# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- WD40 PF00400.32 EJS41220.1 - 5.1e-06 27.1 5.3 0.0039 18.0 0.3 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS41220.1 - 0.00051 20.3 0.0 1.1 9.7 0.0 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3215 PF11503.8 EJS41221.1 - 2.8e-26 91.2 0.0 3.3e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) DUF2004 PF09406.10 EJS41221.1 - 0.055 13.8 0.0 0.09 13.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2004) P34-Arc PF04045.14 EJS41222.1 - 6.9e-92 307.5 1.2 1e-91 306.9 1.2 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Ras PF00071.22 EJS41223.1 - 6.6e-57 191.6 0.3 1.2e-56 190.8 0.3 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS41223.1 - 1.3e-19 70.6 2.4 1.4e-19 70.5 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS41223.1 - 2.3e-10 40.2 0.1 3.9e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EJS41223.1 - 8e-05 22.6 2.2 0.082 12.8 0.1 2.6 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EJS41223.1 - 0.00043 20.4 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EJS41223.1 - 0.059 13.4 0.7 0.2 11.7 0.2 2.0 1 1 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Ras PF00071.22 EJS41224.1 - 1.8e-63 213.0 0.5 2.2e-63 212.7 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS41224.1 - 3.3e-37 127.4 0.3 6e-37 126.5 0.3 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS41224.1 - 4.9e-19 68.4 0.2 6e-19 68.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EJS41224.1 - 9.4e-08 31.7 0.3 1.2e-07 31.4 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EJS41224.1 - 5.7e-07 29.1 0.1 6.6e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJS41224.1 - 1.7e-06 28.1 0.1 2.7e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJS41224.1 - 1.5e-05 25.0 0.7 0.1 12.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EJS41224.1 - 2.4e-05 24.0 0.5 0.00043 19.9 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EJS41224.1 - 0.002 17.7 0.3 0.019 14.5 0.3 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MCM PF00493.23 EJS41224.1 - 0.014 14.5 0.1 0.045 12.8 0.0 1.8 2 1 0 2 2 2 0 MCM P-loop domain AAA_7 PF12775.7 EJS41224.1 - 0.019 14.5 0.1 0.046 13.2 0.1 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 EJS41224.1 - 0.03 14.6 0.1 0.15 12.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 EJS41224.1 - 0.055 13.2 2.0 0.16 11.7 0.8 2.3 1 1 1 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 EJS41224.1 - 0.067 13.6 0.1 0.9 10.0 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJS41224.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF4938 PF16292.5 EJS41224.1 - 0.17 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4938) PWWP PF00855.17 EJS41225.1 - 5.4e-17 62.0 0.6 1.9e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 EJS41225.1 - 0.044 13.8 0.0 0.18 11.8 0.0 2.1 1 0 0 1 1 1 0 TFIIS helical bundle-like domain NBP1 PF08537.10 EJS41226.1 - 2.4e-81 273.8 28.0 5.7e-81 272.6 28.0 1.6 1 1 0 1 1 1 1 Fungal Nap binding protein NBP1 Chibby PF14645.6 EJS41226.1 - 0.52 10.7 7.2 1.1 9.6 2.0 3.2 1 1 2 3 3 3 0 Chibby family TMF_DNA_bd PF12329.8 EJS41226.1 - 1.6 8.8 7.2 0.51 10.4 3.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.14 EJS41226.1 - 2.9 8.2 6.7 1.2 9.5 0.7 2.5 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Occludin_ELL PF07303.13 EJS41226.1 - 4.1 8.2 11.9 1.4 9.7 3.2 2.8 2 1 1 3 3 3 0 Occludin homology domain PIG-U PF06728.13 EJS41227.1 - 2.3e-99 333.0 45.6 2.8e-99 332.7 45.6 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Phosphorylase PF00343.20 EJS41228.1 - 0 1034.8 0.0 0 1034.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.25 EJS41229.1 - 5.5e-79 265.2 0.0 7.1e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41229.1 - 4.1e-31 108.2 0.0 6.4e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJS41229.1 - 1.9e-07 30.4 0.2 3.6e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EJS41229.1 - 0.059 12.4 1.1 0.1 11.7 1.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 ORC4_C PF14629.6 EJS41230.1 - 1.3e-34 119.5 1.2 1.9e-34 118.9 1.2 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EJS41230.1 - 0.00011 22.6 0.1 0.00026 21.4 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJS41230.1 - 0.0026 18.0 0.0 0.01 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EJS41230.1 - 0.065 13.3 0.2 0.43 10.6 0.2 2.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EJS41230.1 - 0.09 13.2 0.1 0.43 11.0 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 EJS41233.1 - 2.1e-55 186.7 0.0 2.6e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS41233.1 - 2.4e-21 76.2 0.0 5.1e-21 75.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS41233.1 - 7e-07 28.9 0.0 9.8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EJS41233.1 - 0.0007 19.2 0.0 0.002 17.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LEA_5 PF00477.17 EJS41233.1 - 0.019 15.4 0.5 0.035 14.6 0.5 1.5 1 0 0 1 1 1 0 Small hydrophilic plant seed protein SRPRB PF09439.10 EJS41233.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EJS41233.1 - 0.098 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S14 PF00253.21 EJS41234.1 - 5.4e-20 70.9 1.4 6e-20 70.8 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e PAPS_reduct PF01507.19 EJS41235.1 - 4.3e-44 150.6 0.0 5.6e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Putative_PNPOx PF01243.20 EJS41237.1 - 1.2e-19 70.3 0.0 2.6e-19 69.2 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EJS41237.1 - 0.0019 17.8 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase like L_biotic_typeA PF04604.13 EJS41237.1 - 0.22 11.4 2.3 0.42 10.5 0.4 2.1 2 0 0 2 2 2 0 Type-A lantibiotic AAA PF00004.29 EJS41238.1 - 1.4e-43 148.5 0.0 2.4e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EJS41238.1 - 4.1e-30 103.6 0.2 1.4e-29 101.9 0.2 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EJS41238.1 - 1.1e-23 83.0 4.5 3.6e-23 81.4 4.5 2.0 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EJS41238.1 - 8.4e-07 28.7 0.0 6.3e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EJS41238.1 - 5e-06 27.0 0.1 0.00012 22.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EJS41238.1 - 8.2e-06 25.7 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EJS41238.1 - 2e-05 24.6 0.0 7.3e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EJS41238.1 - 4.7e-05 23.2 0.0 9.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EJS41238.1 - 5.1e-05 23.6 0.1 0.011 16.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 EJS41238.1 - 0.00011 21.6 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EJS41238.1 - 0.00014 21.9 0.0 0.00041 20.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EJS41238.1 - 0.00018 20.8 0.0 0.00042 19.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EJS41238.1 - 0.00026 21.3 0.2 0.0096 16.3 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_2 PF07724.14 EJS41238.1 - 0.00036 20.7 0.1 0.0013 18.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EJS41238.1 - 0.0007 20.2 0.0 0.0024 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EJS41238.1 - 0.0021 18.2 0.1 0.0053 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 EJS41238.1 - 0.0024 17.6 0.1 0.0083 15.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 EJS41238.1 - 0.007 16.0 0.1 0.2 11.2 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 EJS41238.1 - 0.01 16.3 0.2 0.03 14.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 EJS41238.1 - 0.013 15.0 0.0 0.034 13.7 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 EJS41238.1 - 0.024 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Torsin ATPase PF06745.13 EJS41238.1 - 0.027 13.8 0.1 4 6.7 0.0 2.3 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.21 EJS41238.1 - 0.036 13.4 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EJS41238.1 - 0.07 13.0 0.7 2.3 8.1 0.0 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea PhoH PF02562.16 EJS41238.1 - 0.076 12.5 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Use1 PF09753.9 EJS41238.1 - 0.078 12.7 2.2 0.15 11.8 1.7 1.6 2 0 0 2 2 2 0 Membrane fusion protein Use1 Sigma54_activat PF00158.26 EJS41238.1 - 0.086 12.5 0.0 0.29 10.8 0.0 1.8 1 1 1 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EJS41238.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Vta1 PF04652.16 EJS41238.1 - 0.11 12.5 0.6 0.19 11.7 0.6 1.4 1 0 0 1 1 1 0 Vta1 like NACHT PF05729.12 EJS41238.1 - 0.11 12.4 0.0 0.69 9.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 EJS41238.1 - 0.14 11.4 0.1 1.1 8.5 0.1 2.2 1 1 1 2 2 2 0 Zeta toxin CPT PF07931.12 EJS41238.1 - 0.17 11.8 0.0 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NBP1 PF08537.10 EJS41239.1 - 1e-37 130.3 3.4 1e-37 130.3 3.4 1.7 2 0 0 2 2 2 1 Fungal Nap binding protein NBP1 FapA PF03961.13 EJS41239.1 - 0.18 10.4 0.6 0.22 10.1 0.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A BRE1 PF08647.11 EJS41239.1 - 0.42 10.7 7.5 0.052 13.6 3.2 1.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Prenyltrans PF00432.21 EJS41240.1 - 2.6e-63 209.4 2.9 2e-13 49.8 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EJS41240.1 - 2.5e-05 23.5 0.0 0.00051 19.2 0.0 2.2 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EJS41240.1 - 0.0029 16.8 0.0 3.3 6.7 0.0 3.3 1 1 3 4 4 4 2 Squalene-hopene cyclase N-terminal domain WD40 PF00400.32 EJS41241.1 - 4e-33 112.9 16.7 3.5e-07 30.8 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS41241.1 - 6.4e-09 36.0 2.3 0.039 14.3 0.0 5.3 1 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain HDA2-3 PF11496.8 EJS41242.1 - 6.9e-94 314.3 2.2 6.9e-94 314.3 2.2 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF4407 PF14362.6 EJS41242.1 - 9 5.5 12.3 15 4.8 12.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tox-REase-2 PF15646.6 EJS41242.1 - 9.7 6.4 9.1 1.1 9.4 0.8 3.0 3 1 0 3 3 3 0 Restriction endonuclease fold toxin 2 Sec23_trunk PF04811.15 EJS41243.1 - 3.1e-74 249.6 0.0 4.3e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EJS41243.1 - 7.4e-29 100.3 0.1 1.5e-28 99.3 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EJS41243.1 - 3.8e-27 94.1 0.1 9.5e-27 92.8 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EJS41243.1 - 1.2e-12 47.7 7.6 2.1e-12 46.8 7.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EJS41243.1 - 2.7e-12 46.4 0.0 7.1e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EJS41243.1 - 0.00094 18.5 0.9 0.002 17.5 0.9 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-MIZ PF02891.20 EJS41243.1 - 0.29 10.9 1.8 0.63 9.8 1.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Glycos_transf_2 PF00535.26 EJS41244.1 - 2.2e-30 105.7 0.0 6.9e-30 104.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EJS41244.1 - 3.9e-07 30.2 0.0 6.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EJS41244.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.4 2 0 0 2 2 2 0 Glycosyltransferase like family 2 EF-hand_7 PF13499.6 EJS41245.1 - 1.9e-09 37.8 1.3 8.4e-06 26.2 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EJS41245.1 - 0.00014 21.5 2.8 0.00036 20.2 0.2 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EJS41245.1 - 0.00036 19.9 0.5 0.00036 19.9 0.5 2.7 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EJS41245.1 - 0.0011 18.4 0.6 0.0011 18.4 0.6 2.8 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.9 EJS41245.1 - 0.046 14.0 0.3 0.1 12.9 0.3 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EJS41245.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.6 3 1 1 4 4 4 0 EF-hand domain pair TPR_22 PF18833.1 EJS41246.1 - 9e-37 125.1 0.4 2.9e-36 123.5 0.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJS41246.1 - 1.2e-23 83.3 2.6 6.8e-06 26.5 0.0 8.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJS41246.1 - 7.7e-18 63.1 0.0 0.00041 20.3 0.0 11.2 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 EJS41246.1 - 1.6e-17 62.9 0.0 0.00023 20.8 0.0 9.0 8 1 1 9 9 9 3 TPR repeat TPR_8 PF13181.6 EJS41246.1 - 2.3e-17 61.7 2.7 5.5e-06 26.2 0.0 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJS41246.1 - 5.3e-17 60.9 3.0 2.3e-05 24.0 0.0 10.5 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_14 PF13428.6 EJS41246.1 - 3.8e-16 58.4 0.0 0.031 15.1 0.0 10.2 8 3 2 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EJS41246.1 - 1e-14 54.9 0.0 0.00092 19.8 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EJS41246.1 - 3.8e-10 39.4 0.1 0.1 13.0 0.0 7.8 9 0 0 9 9 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EJS41246.1 - 9e-09 35.4 0.0 0.093 12.9 0.0 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EJS41246.1 - 1.5e-07 31.1 0.0 0.0062 16.2 0.0 3.6 3 0 0 3 3 3 2 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 EJS41246.1 - 7e-07 29.4 4.5 0.29 11.4 0.0 6.2 8 0 0 8 8 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EJS41246.1 - 9.7e-07 29.0 0.1 0.64 10.4 0.0 6.6 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EJS41246.1 - 0.00015 22.2 2.2 24 5.8 0.0 7.0 8 0 0 8 8 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EJS41246.1 - 0.0007 20.1 0.2 0.64 10.5 0.0 3.7 4 0 0 4 4 3 1 Alkyl sulfatase dimerisation TPR_7 PF13176.6 EJS41246.1 - 0.0025 17.7 0.0 2.2 8.5 0.0 4.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 EJS41246.1 - 0.005 17.1 0.5 3 8.2 0.0 4.7 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EJS41246.1 - 0.014 14.8 0.0 2 7.7 0.0 3.4 3 0 0 3 3 3 0 MalT-like TPR region Fis1_TPR_C PF14853.6 EJS41246.1 - 0.054 13.6 0.2 52 4.0 0.0 4.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat CRISPR_Cas2 PF09827.9 EJS41246.1 - 0.07 13.3 0.0 0.96 9.7 0.0 3.0 1 1 1 2 2 2 0 CRISPR associated protein Cas2 TPR_10 PF13374.6 EJS41246.1 - 0.085 12.8 0.0 47 4.0 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M16 PF00675.20 EJS41247.1 - 4.6e-32 111.1 0.0 7.4e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EJS41247.1 - 0.046 13.7 0.2 1 9.3 0.1 2.5 2 1 0 2 2 2 0 Peptidase M16 inactive domain MIP PF00230.20 EJS41248.1 - 9.7e-42 143.2 15.1 1.3e-41 142.8 15.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein MrpF_PhaF PF04066.13 EJS41248.1 - 0.86 10.0 5.7 0.17 12.3 0.8 2.4 2 1 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) DIM1 PF02966.16 EJS41249.1 - 1.8e-67 225.2 1.0 2e-67 225.0 1.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EJS41249.1 - 0.0077 16.2 0.1 0.01 15.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin AAA_14 PF13173.6 EJS41250.1 - 0.041 13.9 0.3 0.12 12.4 0.3 1.8 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EJS41251.1 - 0.0032 17.5 1.0 0.56 10.2 0.0 2.7 3 0 0 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 EJS41251.1 - 0.0081 16.2 0.0 0.71 10.0 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EJS41251.1 - 0.029 14.6 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 EJS41251.1 - 0.038 13.6 0.0 0.88 9.2 0.0 2.3 2 0 0 2 2 2 0 Ras family AAA_16 PF13191.6 EJS41251.1 - 0.039 14.3 0.0 0.091 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain TFIIB PF00382.19 EJS41253.1 - 5.2e-44 148.2 3.3 4.8e-28 97.0 1.2 2.7 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EJS41253.1 - 4.1e-13 48.6 0.7 7.5e-13 47.8 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding DUF1456 PF07308.13 EJS41253.1 - 0.08 13.3 1.0 0.2 12.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) zf-ribbon_3 PF13248.6 EJS41253.1 - 0.11 11.9 0.5 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain SRP54 PF00448.22 EJS41254.1 - 8.7e-79 263.7 3.6 1.4e-78 263.1 0.3 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EJS41254.1 - 1.7e-28 99.2 11.5 1.7e-28 99.2 11.5 4.1 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 EJS41254.1 - 8.9e-14 51.5 2.9 8.9e-14 51.5 2.9 2.1 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 EJS41254.1 - 5.6e-05 23.2 0.0 0.00021 21.4 0.0 2.1 2 1 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EJS41254.1 - 8.6e-05 22.2 2.6 0.00049 19.7 1.1 2.7 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EJS41254.1 - 0.00031 21.2 0.1 0.00031 21.2 0.1 3.0 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EJS41254.1 - 0.00049 20.3 0.0 0.0019 18.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EJS41254.1 - 0.00054 19.3 0.1 0.011 15.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.14 EJS41254.1 - 0.0018 18.2 0.0 0.0064 16.4 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.10 EJS41254.1 - 0.002 17.6 8.4 1.9 7.9 0.1 4.3 4 1 0 4 4 4 2 Signal recognition particle receptor beta subunit MipZ PF09140.11 EJS41254.1 - 0.0088 15.4 0.1 0.15 11.3 0.1 2.4 1 1 0 1 1 1 1 ATPase MipZ AAA_16 PF13191.6 EJS41254.1 - 0.0094 16.4 0.0 0.023 15.1 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_31 PF13614.6 EJS41254.1 - 0.013 15.5 3.2 0.033 14.1 0.3 2.8 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 EJS41254.1 - 0.02 13.9 3.4 0.034 13.1 0.1 2.9 3 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 EJS41254.1 - 0.026 13.8 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 VirC1 protein ATP_bind_1 PF03029.17 EJS41254.1 - 0.026 14.3 0.5 0.091 12.5 0.2 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EJS41254.1 - 0.026 15.1 0.0 0.11 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EJS41254.1 - 0.026 14.8 0.5 0.14 12.5 0.2 2.4 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EJS41254.1 - 0.032 14.1 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 EJS41254.1 - 0.046 13.4 0.3 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EJS41254.1 - 0.056 13.7 0.3 0.79 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EJS41254.1 - 0.092 12.5 2.4 0.18 11.5 0.1 2.5 3 0 0 3 3 3 0 AAA domain CLP1_P PF16575.5 EJS41254.1 - 0.14 12.0 1.1 19 5.0 0.1 2.9 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 EJS41254.1 - 0.5 10.5 3.1 0.76 9.9 0.3 2.8 3 1 0 3 3 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 EJS41254.1 - 0.55 10.1 5.8 4.2 7.2 3.0 2.8 2 1 0 2 2 1 0 NTPase AAA PF00004.29 EJS41254.1 - 2.4 8.6 8.3 0.9 10.0 1.1 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DIL PF01843.19 EJS41255.1 - 7.5e-15 55.1 4.0 2.1e-13 50.4 4.0 2.7 1 1 0 1 1 1 1 DIL domain Ank_5 PF13857.6 EJS41255.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PHF5 PF03660.14 EJS41256.1 - 3.2e-49 165.4 12.7 3.7e-49 165.2 12.7 1.0 1 0 0 1 1 1 1 PHF5-like protein Sec7 PF01369.20 EJS41257.1 - 3.4e-27 95.3 1.2 3.4e-27 95.3 1.2 1.9 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 EJS41257.1 - 0.12 12.9 5.2 3 8.4 0.8 4.2 3 1 0 3 3 3 0 PH domain Glutaredoxin2_C PF04399.13 EJS41257.1 - 0.12 12.2 0.2 9.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain PH_4 PF15404.6 EJS41257.1 - 0.31 10.8 5.9 0.065 13.0 1.2 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3818 PF12825.7 EJS41258.1 - 1.3e-121 405.8 10.5 1.3e-121 405.8 10.5 2.5 2 0 0 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EJS41258.1 - 3.2e-39 133.9 0.8 7.7e-39 132.7 0.8 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EJS41258.1 - 2.7e-13 49.9 1.2 4.4e-12 46.0 1.2 3.0 1 1 0 1 1 1 1 PX domain Peptidase_M35 PF02102.15 EJS41258.1 - 0.017 14.0 0.6 0.032 13.1 0.6 1.4 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Phage_TAC_10 PF10963.8 EJS41258.1 - 0.023 14.9 0.3 0.47 10.7 0.1 2.9 2 0 0 2 2 2 0 Phage tail assembly chaperone L51_S25_CI-B8 PF05047.16 EJS41259.1 - 1.1e-13 50.8 0.0 1.9e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ribosomal_L5_C PF00673.21 EJS41260.1 - 1.6e-22 79.5 0.0 2.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EJS41260.1 - 6.9e-20 71.1 0.1 2.1e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Proteasome PF00227.26 EJS41261.1 - 8e-48 162.4 0.1 9.7e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.25 EJS41262.1 - 4.5e-19 68.9 0.0 6.6e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41262.1 - 8.7e-09 35.0 0.0 3.6e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJS41262.1 - 0.00019 20.3 0.0 0.00023 20.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EJS41262.1 - 0.0033 16.8 0.0 0.0056 16.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJS41262.1 - 0.089 12.7 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-CCCH PF00642.24 EJS41263.1 - 9.3e-16 57.3 26.9 0.00038 20.3 0.4 5.4 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EJS41263.1 - 2e-13 49.9 26.7 6.6e-06 26.0 2.5 5.3 5 0 0 5 5 5 3 Zinc finger domain Torus PF16131.5 EJS41263.1 - 6e-09 36.6 21.7 0.0023 18.6 0.3 5.0 1 1 4 5 5 5 3 Torus domain zf-CCCH_3 PF15663.5 EJS41263.1 - 3.2e-05 24.1 5.7 3.2e-05 24.1 5.7 2.4 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 EJS41263.1 - 0.032 14.0 1.6 0.032 14.0 1.6 3.6 4 1 0 4 4 4 0 CCCH-type zinc finger RPN7 PF10602.9 EJS41264.1 - 2.7e-55 186.8 3.0 2.7e-55 186.8 3.0 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EJS41264.1 - 2e-15 57.2 0.1 1e-14 54.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain TPR_8 PF13181.6 EJS41264.1 - 1.8e-05 24.5 1.5 7.3e-05 22.7 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EJS41264.1 - 0.00035 20.5 1.7 0.0044 17.0 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJS41264.1 - 0.0008 19.6 0.4 0.013 15.8 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJS41264.1 - 0.0016 18.4 0.2 0.16 12.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJS41264.1 - 0.0028 17.4 1.9 0.0035 17.1 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EJS41264.1 - 0.0096 16.7 0.0 2.7 9.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJS41264.1 - 0.011 16.4 0.0 0.35 11.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1897 PF09005.10 EJS41264.1 - 0.019 14.4 3.8 0.57 9.7 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) TPR_10 PF13374.6 EJS41264.1 - 0.023 14.6 0.0 0.66 9.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EJS41264.1 - 0.13 12.7 0.2 0.33 11.4 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5494 PF17598.2 EJS41264.1 - 0.37 10.9 2.4 1.9 8.7 0.2 3.1 2 2 2 4 4 4 0 Family of unknown function (DUF5494) DUF1746 PF08508.10 EJS41265.1 - 4e-05 23.9 1.1 0.044 14.1 0.0 2.7 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1746) RNA_pol_A_bac PF01000.26 EJS41266.1 - 3.8e-29 101.3 0.0 6.7e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EJS41266.1 - 1e-19 69.7 0.0 1.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Prot_ATP_OB_N PF17758.1 EJS41266.1 - 0.028 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Pkinase PF00069.25 EJS41267.1 - 1.4e-55 188.5 0.3 7.5e-55 186.1 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41267.1 - 3.4e-27 95.4 0.2 6.4e-19 68.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EJS41267.1 - 0.00021 21.9 2.4 0.00063 20.4 2.4 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EJS41267.1 - 0.0042 16.1 0.8 0.018 14.0 0.8 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EJS41267.1 - 0.0047 16.3 0.1 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EJS41267.1 - 0.014 14.8 0.0 0.058 12.7 0.0 1.9 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EJS41267.1 - 0.22 11.4 0.6 0.85 9.5 0.0 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family RRM_1 PF00076.22 EJS41268.1 - 1.2e-68 226.8 12.4 3.7e-17 61.9 0.1 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJS41268.1 - 3.5e-08 33.1 0.0 0.0018 17.9 0.0 4.1 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EJS41268.1 - 1.2e-05 25.1 0.0 1.4 8.8 0.0 3.8 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EJS41268.1 - 6.3e-05 23.0 0.5 5.3 7.2 0.0 4.7 4 0 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EJS41268.1 - 0.00034 20.5 0.1 1.5 8.9 0.0 3.9 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EJS41268.1 - 0.0014 18.6 0.6 1.6 8.8 0.0 4.5 4 1 0 4 4 4 1 Limkain b1 PHtD_u1 PF16645.5 EJS41268.1 - 0.084 13.3 0.2 0.25 11.8 0.2 1.8 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein SET_assoc PF11767.8 EJS41268.1 - 0.088 12.5 0.4 47 3.7 0.0 3.8 5 0 0 5 5 5 0 Histone lysine methyltransferase SET associated TRAM_LAG1_CLN8 PF03798.16 EJS41269.1 - 5e-32 111.3 18.3 5e-32 111.3 18.3 1.4 2 0 0 2 2 2 1 TLC domain IF-2B PF01008.17 EJS41270.1 - 5.1e-91 304.8 0.0 6e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyclin_N PF00134.23 EJS41271.1 - 1.6e-40 137.7 0.3 4.6e-40 136.3 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EJS41271.1 - 2.2e-32 111.7 0.0 5.1e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Peptidase_M16 PF00675.20 EJS41272.1 - 4.8e-39 133.7 0.0 4.4e-38 130.6 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EJS41272.1 - 7.8e-15 55.4 5.9 0.00014 22.0 0.0 5.2 4 1 0 4 4 4 4 Peptidase M16 inactive domain LETM1 PF07766.13 EJS41273.1 - 1.2e-89 300.2 3.9 1.2e-89 300.2 3.9 1.4 2 0 0 2 2 2 1 LETM1-like protein GPAT_N PF14829.6 EJS41273.1 - 0.007 16.3 0.8 0.024 14.6 0.0 2.3 3 0 0 3 3 3 1 Glycerol-3-phosphate acyltransferase N-terminal LSM14 PF12701.7 EJS41274.1 - 1.6e-25 89.0 0.0 3.2e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EJS41274.1 - 7.1e-05 23.6 15.3 7.1e-05 23.6 15.3 4.7 4 1 0 4 4 4 1 FDF domain SM-ATX PF14438.6 EJS41274.1 - 0.014 15.6 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain Vac_ImportDeg PF09783.9 EJS41274.1 - 0.017 14.9 0.5 0.032 14.0 0.5 1.4 1 0 0 1 1 1 0 Vacuolar import and degradation protein YdfA_immunity PF12127.8 EJS41274.1 - 0.14 11.2 3.5 0.21 10.6 3.5 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial FAM75 PF14650.6 EJS41274.1 - 0.39 10.2 16.8 0.32 10.5 15.0 1.5 1 1 0 1 1 1 0 FAM75 family Acetyltransf_1 PF00583.25 EJS41275.1 - 1.2e-08 35.2 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EJS41275.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EJS41275.1 - 1.2e-05 25.6 0.0 2.2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJS41275.1 - 4.2e-05 23.5 0.0 6.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EJS41275.1 - 0.077 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tom5 PF10642.9 EJS41276.1 - 3.2e-20 71.9 0.3 3.5e-20 71.8 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Mcl1_mid PF12341.8 EJS41277.1 - 8.7e-84 281.4 0.0 7e-83 278.4 0.0 2.3 2 1 1 3 3 3 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 EJS41277.1 - 2.4e-06 27.7 0.1 0.35 11.2 0.0 4.1 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJS41278.1 - 8.7e-17 61.2 3.6 3.6e-05 24.4 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 EJS41278.1 - 0.013 14.8 0.1 1 8.6 0.0 3.3 4 0 0 4 4 4 0 WD40-like domain Cytochrom_D1 PF02239.16 EJS41278.1 - 0.08 11.5 0.0 0.28 9.7 0.0 1.8 1 1 0 1 1 1 0 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 EJS41278.1 - 0.13 12.6 0.0 1.3 9.3 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Rrn6 PF10214.9 EJS41278.1 - 2.7 6.4 6.3 3.8 5.9 6.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ammonium_transp PF00909.21 EJS41279.1 - 1.2e-122 409.5 26.1 1.3e-122 409.3 26.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 EJS41279.1 - 0.0096 15.9 0.2 0.0096 15.9 0.2 3.4 4 0 0 4 4 4 1 Bacteriophage P21 holin S Acyltransferase PF01553.21 EJS41281.1 - 1.9e-12 46.9 0.0 2.8e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Kinesin PF00225.23 EJS41282.1 - 1.5e-106 356.2 7.5 1.5e-106 356.2 7.5 2.4 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EJS41282.1 - 1.8e-56 190.2 0.5 1.8e-56 190.2 0.5 2.8 3 1 1 4 4 4 1 Microtubule binding Tenui_N PF05733.11 EJS41282.1 - 0.0025 17.4 1.1 0.0025 17.4 1.1 2.3 2 0 0 2 2 2 1 Tenuivirus/Phlebovirus nucleocapsid protein Rrp15p PF07890.12 EJS41283.1 - 5.7e-29 101.2 14.5 5.7e-29 101.2 14.5 2.4 2 1 0 2 2 2 1 Rrp15p Glyco_hydro_63 PF03200.16 EJS41283.1 - 0.038 12.8 0.9 0.051 12.3 0.9 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain Ndc1_Nup PF09531.10 EJS41283.1 - 4.4 5.9 6.8 5 5.7 6.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CBF PF03914.17 EJS41284.1 - 4e-34 118.1 0.8 9.4e-34 116.9 0.8 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Asn_synthase PF00733.21 EJS41285.1 - 3.1e-93 313.2 0.5 3.5e-54 184.8 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EJS41285.1 - 3.1e-33 114.3 0.0 4.9e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EJS41285.1 - 3.1e-25 88.9 0.0 6e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EJS41285.1 - 1.2e-05 24.9 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EJS41285.1 - 0.05 12.7 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase LIDHydrolase PF10230.9 EJS41286.1 - 3.2e-74 249.8 3.7 3.7e-74 249.6 3.7 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 EJS41286.1 - 0.0021 16.8 0.1 0.0035 16.1 0.1 1.4 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.7 EJS41286.1 - 0.0056 17.3 0.0 0.0058 17.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 EJS41286.1 - 0.023 13.8 2.6 0.99 8.4 0.1 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF1749 PF08538.10 EJS41286.1 - 0.043 12.9 0.2 0.084 11.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 EJS41286.1 - 0.051 12.8 0.1 0.075 12.3 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EJS41286.1 - 0.081 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EJS41286.1 - 0.094 12.6 1.6 0.19 11.6 0.2 2.0 2 0 0 2 2 2 0 Lipase (class 3) MARVEL PF01284.23 EJS41287.1 - 2.7e-29 102.0 12.1 3.6e-29 101.6 12.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4956 PF16316.5 EJS41287.1 - 0.18 11.4 2.0 4.1 7.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) SH3_1 PF00018.28 EJS41288.1 - 7.8e-14 51.0 0.0 1.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJS41288.1 - 2e-11 43.6 0.0 3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJS41288.1 - 6.9e-11 41.7 0.0 9.8e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 EJS41288.1 - 0.0026 17.8 9.2 0.0035 17.4 9.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 EJS41288.1 - 0.014 16.0 10.2 0.023 15.3 10.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 EJS41288.1 - 0.053 13.5 1.6 0.056 13.4 1.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MSA-2c PF12238.8 EJS41288.1 - 2.8 7.9 15.1 11 6.0 13.7 2.0 2 0 0 2 2 2 0 Merozoite surface antigen 2c NCA2 PF08637.10 EJS41289.1 - 1.7e-100 336.0 1.3 1.7e-100 336.0 1.3 1.9 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 MitMem_reg PF13012.6 EJS41289.1 - 0.035 14.5 1.6 0.76 10.2 0.0 3.1 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function Terminase_4 PF05119.12 EJS41289.1 - 0.038 14.4 0.0 3 8.3 0.0 3.0 3 0 0 3 3 3 0 Phage terminase, small subunit Med12 PF09497.10 EJS41289.1 - 0.085 13.2 2.6 0.35 11.2 0.4 2.9 3 1 0 4 4 4 0 Transcription mediator complex subunit Med12 mCpol PF18182.1 EJS41289.1 - 7.5 6.9 5.8 7.5 6.9 0.0 3.4 4 1 0 4 4 4 0 minimal CRISPR polymerase domain MFS_1 PF07690.16 EJS41290.1 - 1.8e-31 109.3 32.3 1.8e-31 109.3 32.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Vps62 PF06101.11 EJS41291.1 - 0.00031 19.2 6.3 0.012 13.9 4.1 2.5 2 1 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 SKN1 PF03935.15 EJS41292.1 - 8.1e-255 845.9 5.5 1e-254 845.6 5.5 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SUV3_C PF12513.8 EJS41293.1 - 1e-17 63.8 1.2 2.8e-17 62.4 1.2 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EJS41293.1 - 1.2e-13 51.4 0.0 4.1e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TcpS PF17456.2 EJS41293.1 - 0.046 13.8 1.4 0.24 11.4 0.2 2.4 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S Thiolase_N PF00108.23 EJS41294.1 - 4.7e-95 317.9 2.9 5.9e-95 317.5 2.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EJS41294.1 - 2e-46 156.6 1.2 9.2e-46 154.5 0.2 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EJS41294.1 - 3.9e-06 26.6 1.8 1.1e-05 25.2 1.7 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EJS41294.1 - 0.21 11.4 2.0 6.4 6.7 0.9 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pkinase PF00069.25 EJS41295.1 - 2.8e-44 151.5 3.9 2.9e-38 131.8 0.4 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41295.1 - 3e-19 69.3 0.3 5.7e-18 65.1 0.1 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS41295.1 - 0.00014 21.3 0.0 0.00031 20.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJS41295.1 - 0.018 15.0 0.4 0.04 13.8 0.3 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EJS41295.1 - 0.019 14.6 6.9 0.24 11.0 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EJS41295.1 - 0.051 12.9 0.2 0.09 12.1 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4666 PF15697.5 EJS41295.1 - 0.17 12.6 2.7 0.38 11.5 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) RNA_pol_Rbc25 PF08292.12 EJS41295.1 - 0.17 12.1 4.7 0.34 11.1 4.7 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF4175 PF13779.6 EJS41295.1 - 1.4 6.7 7.3 1.9 6.3 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RMI1_N PF08585.12 EJS41296.1 - 2.6e-17 63.3 0.0 3.1e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein Apis_Csd PF11671.8 EJS41296.1 - 0.021 14.8 0.6 0.033 14.2 0.6 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Spo7_2_N PF15407.6 EJS41296.1 - 0.17 11.6 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 Ribosomal_S16 PF00886.19 EJS41299.1 - 1e-26 92.8 0.1 1.3e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 NUC173 PF08161.12 EJS41300.1 - 7.9e-69 231.4 0.4 1.4e-66 224.1 0.2 3.4 3 0 0 3 3 3 1 NUC173 domain Cnd1 PF12717.7 EJS41300.1 - 0.0033 17.5 0.4 0.0033 17.5 0.4 4.6 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 BEN PF10523.9 EJS41300.1 - 0.023 14.9 0.3 1.4 9.2 0.0 3.9 4 0 0 4 4 4 0 BEN domain Ribonuc_2-5A PF06479.12 EJS41300.1 - 1.6 9.0 4.0 5.6 7.1 0.3 3.3 3 0 0 3 3 3 0 Ribonuclease 2-5A Bromo_TP PF07524.13 EJS41301.1 - 2.5e-08 33.8 0.0 2.4e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Bromodomain associated Tox-HNH-HHH PF15637.6 EJS41301.1 - 0.025 14.7 0.0 0.076 13.2 0.0 1.8 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Josephin PF02099.17 EJS41301.1 - 0.028 14.5 0.0 0.089 12.9 0.0 1.8 1 1 0 1 1 1 0 Josephin Na_trans_assoc PF06512.13 EJS41301.1 - 1.1 9.4 16.8 1.4 9.2 15.8 1.7 1 1 0 1 1 1 0 Sodium ion transport-associated Clat_adaptor_s PF01217.20 EJS41302.1 - 2.8e-18 66.2 0.7 4.1e-18 65.7 0.7 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-TFIIIC PF12660.7 EJS41303.1 - 2.6e-07 30.5 0.0 7.2e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex ANAPC4_WD40 PF12894.7 EJS41303.1 - 0.13 12.6 0.1 1.9 8.8 0.0 2.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain NPC1_N PF16414.5 EJS41304.1 - 2.1e-82 276.3 11.3 3.8e-82 275.5 11.3 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EJS41304.1 - 1.6e-61 208.4 14.8 1.5e-58 198.7 14.8 2.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EJS41304.1 - 2e-40 138.2 6.2 2e-40 138.2 6.2 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 EJS41304.1 - 4.5e-09 34.6 18.2 1.1e-07 30.0 15.5 2.4 2 0 0 2 2 2 2 AcrB/AcrD/AcrF family MMPL PF03176.15 EJS41304.1 - 0.0086 15.0 11.4 0.013 14.4 0.0 2.2 2 0 0 2 2 2 1 MMPL family TMEM18 PF14770.6 EJS41304.1 - 0.45 10.5 0.0 0.45 10.5 0.0 3.9 3 1 0 3 3 3 0 Transmembrane protein 18 Pil1 PF13805.6 EJS41305.1 - 1.6e-125 418.0 0.3 1.8e-125 417.8 0.3 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.10 EJS41305.1 - 0.17 12.1 0.3 0.17 12.1 0.3 2.2 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit ThiF PF00899.21 EJS41306.1 - 0.00026 20.4 0.0 0.012 15.0 0.0 2.3 2 1 0 2 2 2 2 ThiF family EAP30 PF04157.16 EJS41307.1 - 1.4e-53 181.6 0.0 1.5e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Phage_Mu_Gam PF07352.12 EJS41307.1 - 0.099 12.5 1.0 0.91 9.4 0.3 2.4 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein Sulfate_transp PF00916.20 EJS41308.1 - 1.5e-103 346.5 22.1 1.9e-103 346.2 22.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EJS41308.1 - 1.2e-25 89.4 0.2 2.8e-25 88.2 0.2 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EJS41308.1 - 8.2e-05 23.0 6.2 8.2e-05 23.0 6.2 2.9 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily Spore_YabQ PF09578.10 EJS41308.1 - 0.00032 20.9 11.6 0.0023 18.1 3.1 3.2 2 1 1 3 3 3 2 Spore cortex protein YabQ (Spore_YabQ) Gp-FAR-1 PF05823.12 EJS41308.1 - 0.016 15.6 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Cytochrom_B_C PF00032.17 EJS41308.1 - 0.2 12.0 3.7 2.5 8.4 0.7 2.8 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF1072 PF06380.11 EJS41308.1 - 2.2 8.2 8.9 0.33 10.8 2.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) ETF PF01012.21 EJS41309.1 - 6.9e-33 114.1 0.0 1.4e-32 113.1 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EJS41309.1 - 1.7e-31 108.1 0.1 2.9e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SpoVT_C PF15714.5 EJS41310.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor ICL PF00463.21 EJS41311.1 - 1.8e-167 558.0 0.0 2.1e-167 557.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EJS41311.1 - 1.9e-06 27.5 0.0 2.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Rad21_Rec8_N PF04825.13 EJS41312.1 - 8e-16 58.2 0.6 2.9e-15 56.4 0.6 1.9 1 1 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Copper-fist PF00649.18 EJS41313.1 - 1.7e-21 75.4 0.7 3.9e-21 74.3 0.7 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain RNA_pol_Rpb2_6 PF00562.28 EJS41314.1 - 6e-114 381.1 0.0 1.2e-113 380.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EJS41314.1 - 5.4e-52 176.3 0.1 7.6e-52 175.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EJS41314.1 - 1.7e-39 135.4 0.0 5.7e-39 133.7 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 EJS41314.1 - 4.4e-28 97.3 0.0 1.5e-27 95.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 EJS41314.1 - 6.9e-23 80.4 0.0 1.4e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EJS41314.1 - 9.8e-17 61.1 0.0 6.1e-15 55.4 0.0 2.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Mito_carr PF00153.27 EJS41315.1 - 1.1e-73 243.2 1.8 7.1e-27 93.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EJS41315.1 - 3.7e-05 23.0 1.0 0.72 9.0 0.0 3.8 3 1 0 4 4 4 3 Gammaproteobacterial serine protease zf-C2H2 PF00096.26 EJS41316.1 - 1.5e-09 37.8 9.0 0.00038 20.8 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJS41316.1 - 3e-06 27.6 9.6 0.009 16.8 1.0 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 EJS41316.1 - 0.00068 19.9 5.4 0.012 16.0 0.4 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EJS41316.1 - 0.0019 18.6 0.4 0.0019 18.6 0.4 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EJS41316.1 - 0.0075 16.5 3.4 0.52 10.7 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EJS41316.1 - 0.15 12.7 2.5 0.17 12.5 0.2 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 EJS41316.1 - 2.3 8.0 7.6 13 5.6 0.0 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EJS41317.1 - 1.5e-10 40.9 12.2 5.7e-05 23.4 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJS41317.1 - 4.7e-07 30.1 11.1 0.0026 18.5 1.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EJS41317.1 - 0.00037 20.8 1.3 0.00037 20.8 1.3 4.2 5 0 0 5 5 5 1 Zinc-finger double domain zf-met PF12874.7 EJS41317.1 - 0.0018 18.6 6.3 0.0078 16.6 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EJS41317.1 - 0.0098 16.2 6.3 0.7 10.3 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 EJS41317.1 - 0.34 10.9 8.7 2.9 8.0 0.5 2.5 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 EJS41317.1 - 4.9 7.0 15.0 13 5.7 0.1 3.4 3 1 0 3 3 3 0 C2H2-type zinc-finger domain eIF-6 PF01912.18 EJS41318.1 - 4.5e-82 274.2 0.4 5.7e-82 273.9 0.4 1.1 1 0 0 1 1 1 1 eIF-6 family MCM PF00493.23 EJS41319.1 - 1.5e-101 338.2 0.0 2.9e-101 337.2 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EJS41319.1 - 1.4e-36 125.1 0.3 2.6e-36 124.2 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EJS41319.1 - 1.6e-28 98.9 2.5 1.6e-28 98.9 2.5 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EJS41319.1 - 1.5e-18 67.3 5.8 9.4e-18 64.7 5.8 2.5 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 EJS41319.1 - 3.7e-06 27.0 0.0 2.4e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EJS41319.1 - 9.4e-06 25.1 0.0 0.00036 20.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EJS41319.1 - 0.0025 17.7 0.0 0.0092 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJS41319.1 - 0.0049 17.3 1.5 1.4 9.3 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 EJS41319.1 - 0.1 12.3 0.1 4.4 7.0 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain ATP-synt_G PF04718.15 EJS41320.1 - 2.2e-32 111.8 0.4 2.7e-32 111.6 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Fungal_trans PF04082.18 EJS41321.1 - 2.5e-77 259.5 1.7 2.5e-77 259.5 1.7 3.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EJS41321.1 - 7.9e-07 29.2 11.5 0.0017 18.7 4.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJS41321.1 - 1.1e-05 25.8 7.7 0.022 15.6 3.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EJS41321.1 - 0.17 11.9 5.2 1.5 8.9 1.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EJS41321.1 - 0.32 11.3 6.1 0.14 12.5 0.8 2.9 3 1 1 4 4 4 0 C2H2-type zinc ribbon MRG PF05712.13 EJS41322.1 - 5e-44 150.0 0.7 8.8e-44 149.2 0.7 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EJS41322.1 - 5.5e-06 26.2 0.3 1.3e-05 24.9 0.3 1.6 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain NPDC1 PF06809.11 EJS41322.1 - 0.096 11.7 0.2 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Macoilin PF09726.9 EJS41322.1 - 0.31 9.5 3.6 0.4 9.2 3.6 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_M41 PF01434.18 EJS41323.1 - 6.3e-61 205.6 0.1 1.1e-60 204.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EJS41323.1 - 2.4e-40 138.0 0.0 5.4e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS41323.1 - 1.7e-08 34.1 0.0 6.4e-08 32.3 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EJS41323.1 - 1.4e-05 25.6 0.2 6.2e-05 23.4 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EJS41323.1 - 0.00023 20.5 0.0 0.00047 19.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EJS41323.1 - 0.00061 20.1 0.7 0.1 12.9 0.2 3.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 EJS41323.1 - 0.00077 19.2 0.0 0.006 16.3 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EJS41323.1 - 0.0046 17.0 0.1 0.015 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SpoU_sub_bind PF08032.12 EJS41323.1 - 0.012 15.9 0.3 4.5 7.6 0.4 3.4 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding IstB_IS21 PF01695.17 EJS41323.1 - 0.026 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EJS41323.1 - 0.038 14.1 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EJS41323.1 - 0.043 13.2 0.2 0.49 9.7 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 EJS41323.1 - 0.047 13.3 1.0 1.1 8.8 0.4 2.5 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EJS41323.1 - 0.048 13.0 0.2 0.12 11.7 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EJS41323.1 - 0.052 14.1 0.1 0.31 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EJS41323.1 - 0.094 12.2 0.4 0.46 9.9 0.2 2.0 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 EJS41323.1 - 0.098 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 EJS41323.1 - 0.13 12.4 0.0 0.51 10.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Cyclin_C_2 PF16899.5 EJS41324.1 - 5.5e-30 103.8 0.0 2.7e-29 101.6 0.0 2.1 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 EJS41324.1 - 2.1e-10 40.4 0.9 4e-10 39.5 0.9 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 EJS41324.1 - 0.0028 17.7 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Glyco_hydro_65m PF03632.15 EJS41325.1 - 6.4e-32 110.8 4.2 4.6e-30 104.7 1.0 2.5 2 1 1 3 3 3 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 EJS41325.1 - 2.6e-28 99.2 0.0 4.5e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 EJS41325.1 - 0.00011 22.1 0.1 0.00049 20.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.25 EJS41325.1 - 0.12 12.5 0.3 0.44 10.7 0.0 2.0 2 0 0 2 2 2 0 F5/8 type C domain DUF551 PF04448.12 EJS41325.1 - 0.16 13.0 0.0 1.3 10.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF551) Adaptin_N PF01602.20 EJS41327.1 - 9.9e-132 440.1 17.3 1.5e-131 439.6 17.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EJS41327.1 - 4.4e-13 49.5 0.2 9e-13 48.5 0.2 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Arrestin_C PF02752.22 EJS41328.1 - 4.8e-10 40.0 9.6 2.7e-07 31.1 4.8 4.0 2 2 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EJS41328.1 - 0.054 13.6 0.0 0.23 11.5 0.0 2.1 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Nop14 PF04147.12 EJS41328.1 - 0.082 11.1 2.8 0.13 10.5 2.8 1.2 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EJS41328.1 - 1.2 8.9 11.3 0.42 10.4 6.6 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NOA36 PF06524.12 EJS41328.1 - 6.1 6.1 16.8 1.1 8.5 12.5 1.9 2 0 0 2 2 2 0 NOA36 protein Lgl_C PF08596.10 EJS41329.1 - 3.2e-147 490.3 0.4 2.6e-146 487.3 0.0 2.2 2 1 1 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 EJS41329.1 - 3.4e-08 33.7 0.1 0.16 12.3 0.0 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EJS41329.1 - 0.002 17.5 0.4 0.0049 16.2 0.4 1.6 1 0 0 1 1 1 1 WD40-like domain WD40 PF00400.32 EJS41329.1 - 0.087 13.7 0.1 43 5.2 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 EJS41329.1 - 0.1 11.9 1.1 1.7 7.8 0.3 2.6 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus tRNA-synt_His PF13393.6 EJS41330.1 - 1.1e-37 130.0 0.0 9.2e-37 127.0 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EJS41330.1 - 4.6e-14 52.3 0.1 8.8e-14 51.4 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EJS41330.1 - 0.0023 17.5 0.1 0.0063 16.1 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 EJS41330.1 - 0.015 14.4 0.0 0.061 12.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Gln-synt_C PF00120.24 EJS41331.1 - 1.1e-19 70.6 0.0 1.8e-15 56.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EJS41331.1 - 9.5e-14 50.9 0.0 2.4e-13 49.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain V-ATPase_H_N PF03224.14 EJS41332.1 - 5.4e-70 236.2 14.8 5.4e-70 236.2 14.8 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EJS41332.1 - 2.9e-41 140.2 0.1 2.9e-41 140.2 0.1 3.4 3 1 0 4 4 4 1 V-ATPase subunit H RPAP3_C PF13877.6 EJS41332.1 - 0.16 12.5 6.0 0.59 10.7 0.4 3.4 3 2 0 3 3 3 0 Potential Monad-binding region of RPAP3 Evr1_Alr PF04777.13 EJS41334.1 - 2.3e-23 82.6 0.1 3.6e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 EJS41334.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 APOBEC1 TIP41 PF04176.13 EJS41335.1 - 3.1e-64 215.6 3.3 4.8e-64 215.0 3.3 1.3 1 0 0 1 1 1 1 TIP41-like family SAC3_GANP PF03399.16 EJS41336.1 - 1.2e-15 57.7 11.5 1.4e-13 50.9 11.5 2.1 1 1 0 1 1 1 1 SAC3/GANP family PCI PF01399.27 EJS41336.1 - 0.017 15.7 2.0 0.086 13.4 0.4 2.4 2 0 0 2 2 2 0 PCI domain CSN8_PSD8_EIF3K PF10075.9 EJS41336.1 - 0.079 12.9 7.7 0.053 13.5 3.5 2.3 1 1 1 2 2 2 0 CSN8/PSMD8/EIF3K family tRNA-synt_2d PF01409.20 EJS41337.1 - 2.2e-47 161.6 0.2 1.4e-26 93.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EJS41337.1 - 1.6e-27 95.7 0.1 1.5e-26 92.6 0.0 2.5 2 1 0 2 2 2 1 Ferredoxin-fold anticodon binding domain DUF3811 PF11656.8 EJS41337.1 - 0.019 15.3 0.1 0.053 13.9 0.1 1.8 1 0 0 1 1 1 0 YjbD family (DUF3811) FAD_binding_1 PF00667.20 EJS41338.1 - 3.8e-30 105.1 0.0 9e-30 103.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EJS41338.1 - 1.2e-22 80.6 0.0 3.1e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EJS41338.1 - 7.8e-10 39.4 0.0 2.3e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ATG11 PF10377.9 EJS41339.1 - 2e-42 144.3 0.0 2e-42 144.3 0.0 2.4 3 0 0 3 3 3 1 Autophagy-related protein 11 TrbH PF07283.11 EJS41339.1 - 0.013 15.7 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 Conjugal transfer protein TrbH LPP PF04728.13 EJS41339.1 - 0.29 11.6 8.4 28 5.2 0.3 4.7 3 0 0 3 3 3 0 Lipoprotein leucine-zipper YscO PF07321.12 EJS41339.1 - 0.34 10.9 9.2 0.31 11.0 3.2 2.6 2 0 0 2 2 2 0 Type III secretion protein YscO TSC22 PF01166.18 EJS41339.1 - 0.99 9.8 18.8 2.2 8.6 1.3 5.6 4 1 1 5 5 5 0 TSC-22/dip/bun family DUF4140 PF13600.6 EJS41339.1 - 4.9 7.7 10.1 46 4.5 0.4 4.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HMG_box PF00505.19 EJS41340.1 - 6.3e-26 90.6 1.8 6.3e-26 90.6 1.8 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EJS41340.1 - 1e-18 67.7 1.4 1.4e-18 67.2 1.4 1.2 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EJS41340.1 - 0.0032 18.0 1.2 0.0049 17.4 0.0 1.7 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 EJS41340.1 - 0.054 13.5 2.8 0.071 13.1 2.4 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box 5 YABBY PF04690.13 EJS41340.1 - 0.095 13.3 1.4 0.098 13.2 1.0 1.3 1 1 0 1 1 1 0 YABBY protein Pkinase PF00069.25 EJS41341.1 - 3.4e-61 206.9 0.0 4.1e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41341.1 - 1.5e-28 99.8 0.0 2.1e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJS41341.1 - 0.00044 19.3 0.0 0.00074 18.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EJS41341.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SIP1 PF04938.12 EJS41342.1 - 1.4e-12 47.8 0.6 1.6e-10 41.1 0.6 2.2 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3328 PF11807.8 EJS41342.1 - 0.044 13.5 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Mito_carr PF00153.27 EJS41343.1 - 1.8e-60 200.8 1.6 3e-21 75.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CM_2 PF01817.21 EJS41344.1 - 0.00021 21.6 0.0 0.37 11.2 0.1 2.8 2 1 0 2 2 2 2 Chorismate mutase type II HMG_box PF00505.19 EJS41345.1 - 3.4e-17 62.6 1.3 1.1e-16 61.0 1.3 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EJS41345.1 - 8.3e-06 26.3 0.2 8.3e-06 26.3 0.2 1.9 2 0 0 2 2 2 1 HMG-box domain Trypan_PARP PF05887.11 EJS41345.1 - 0.31 11.0 1.9 0.5 10.4 1.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Fe-S_biosyn PF01521.20 EJS41346.1 - 8.7e-14 51.7 0.1 3e-12 46.7 0.1 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Hist_deacetyl PF00850.19 EJS41347.1 - 4.6e-69 233.2 0.0 6.2e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Spermine_synth PF01564.17 EJS41348.1 - 7.2e-76 253.8 0.0 9.7e-76 253.4 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EJS41348.1 - 3.8e-26 90.7 0.1 6.5e-26 90.0 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EJS41348.1 - 0.00027 21.6 0.0 0.00056 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJS41348.1 - 0.0055 17.4 0.1 0.027 15.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain RNase_H2-Ydr279 PF09468.10 EJS41348.1 - 0.056 13.6 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Methyltransf_18 PF12847.7 EJS41348.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Med1 PF10744.9 EJS41349.1 - 1.2e-24 87.1 9.4 9e-22 77.7 4.9 3.2 1 1 1 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 DUF4891 PF16232.5 EJS41349.1 - 0.13 12.8 0.1 0.84 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4891) Not3 PF04065.15 EJS41350.1 - 1.3e-66 224.4 37.2 1e-65 221.4 30.9 2.9 2 1 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EJS41350.1 - 1.2e-36 125.7 2.7 1.2e-36 125.7 2.7 2.6 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family NACHT PF05729.12 EJS41350.1 - 0.29 11.0 2.2 0.44 10.5 1.2 1.7 1 1 0 1 1 1 0 NACHT domain Plasmid_RAQPRD PF09686.10 EJS41350.1 - 1.4 9.2 6.4 0.56 10.5 1.3 2.8 2 1 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF5395 PF17373.2 EJS41350.1 - 1.8 9.3 5.6 1.4 9.6 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5395) LMWPc PF01451.21 EJS41351.1 - 1.2e-51 174.8 0.0 1.4e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Transketolase_N PF00456.21 EJS41352.1 - 2.1e-164 546.4 0.0 4.1e-164 545.4 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EJS41352.1 - 1.7e-47 161.4 0.0 3.2e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EJS41352.1 - 4.9e-16 58.7 0.0 1.2e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EJS41352.1 - 0.0004 19.7 0.0 0.0008 18.7 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EJS41352.1 - 0.0023 17.0 0.0 0.0047 15.9 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component XFP_C PF09363.10 EJS41352.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 XFP C-terminal domain Opy2 PF09463.10 EJS41353.1 - 1.4e-09 38.1 17.4 2.2e-09 37.5 17.4 1.3 1 0 0 1 1 1 1 Opy2 protein LRR19-TM PF15176.6 EJS41353.1 - 0.00015 21.7 1.8 0.017 15.1 0.0 2.6 2 0 0 2 2 2 1 Leucine-rich repeat family 19 TM domain DUF2076 PF09849.9 EJS41353.1 - 0.0061 16.6 2.9 0.0061 16.6 2.9 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) LapA_dom PF06305.11 EJS41353.1 - 0.15 11.9 0.4 0.34 10.8 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2890 PF11081.8 EJS41353.1 - 0.8 9.8 2.9 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Mid2 PF04478.12 EJS41353.1 - 3 7.7 12.0 0.32 10.8 0.8 3.4 2 1 0 3 3 3 0 Mid2 like cell wall stress sensor DUF19 PF01579.18 EJS41354.1 - 0.0083 15.9 0.3 0.016 15.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF19) DUF4116 PF13475.6 EJS41354.1 - 0.18 11.6 0.4 0.48 10.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) CIMR PF00878.18 EJS41355.1 - 1.5e-09 38.0 1.0 5.3e-05 23.3 0.1 3.1 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EJS41355.1 - 1e-06 28.0 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor PRKCSH_1 PF13015.6 EJS41355.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 EJS41355.1 - 4.3e-05 23.5 0.4 9.1e-05 22.4 0.4 1.3 1 1 0 1 1 1 1 Autophagy-related protein 27 SRF-TF PF00319.18 EJS41356.1 - 1.1e-21 76.1 0.1 2e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ceramidase PF05875.12 EJS41357.1 - 3.8e-88 295.3 17.1 4.4e-88 295.1 17.1 1.0 1 0 0 1 1 1 1 Ceramidase DUF2721 PF11026.8 EJS41357.1 - 4.2 7.3 7.5 0.79 9.6 0.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Radical_SAM_C PF16199.5 EJS41358.1 - 5.7e-33 112.8 0.0 1.2e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EJS41358.1 - 4.9e-17 62.8 0.8 1.2e-16 61.5 0.1 2.0 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EJS41358.1 - 4.4e-10 39.8 0.1 7.7e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJS41358.1 - 3.6e-06 26.9 0.0 7.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJS41358.1 - 0.03 14.7 0.1 0.064 13.7 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BRO1 PF03097.18 EJS41359.1 - 6.2e-92 308.4 7.3 9.1e-92 307.8 7.3 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EJS41359.1 - 1.9e-25 89.8 7.9 1.9e-25 89.8 7.9 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV CAP_N PF01213.19 EJS41359.1 - 1.8 8.0 5.3 13 5.1 2.3 2.9 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF3535 PF12054.8 EJS41360.1 - 5.1e-120 401.6 0.2 3.2e-119 399.0 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EJS41360.1 - 1.6e-65 221.1 0.0 3.4e-65 220.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJS41360.1 - 3.1e-19 69.4 0.0 2.5e-18 66.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HEAT PF02985.22 EJS41360.1 - 9.6e-12 44.1 2.5 0.054 13.8 0.0 7.9 8 0 0 8 8 8 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EJS41360.1 - 6.3e-07 29.9 0.2 1 10.0 0.0 6.0 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region ResIII PF04851.15 EJS41360.1 - 1.9e-05 24.8 0.1 9.2e-05 22.5 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HEAT_EZ PF13513.6 EJS41360.1 - 0.00053 20.4 1.8 13 6.4 0.0 5.9 6 0 0 6 6 6 1 HEAT-like repeat TAF6_C PF07571.13 EJS41360.1 - 0.0029 17.9 0.1 11 6.4 0.0 4.5 4 0 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain ERCC3_RAD25_C PF16203.5 EJS41360.1 - 0.018 14.3 0.0 0.046 12.9 0.0 1.7 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase GUN4_N PF16416.5 EJS41360.1 - 0.033 14.2 0.1 0.33 11.0 0.0 2.7 2 0 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal Mt_ATP-synt_B PF05405.14 EJS41361.1 - 5.7e-56 188.6 8.9 7.4e-56 188.3 8.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) APC_u15 PF16636.5 EJS41361.1 - 0.071 13.5 0.5 0.23 11.9 0.2 2.0 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 SapB_1 PF05184.15 EJS41361.1 - 0.097 12.7 0.0 0.39 10.8 0.0 2.1 1 1 0 1 1 1 0 Saposin-like type B, region 1 DUF5315 PF17242.2 EJS41362.1 - 8.3e-23 80.0 0.9 1.4e-22 79.2 0.9 1.4 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) CdvA PF18822.1 EJS41362.1 - 0.0032 17.3 0.6 0.0062 16.4 0.6 1.5 1 0 0 1 1 1 1 CdvA-like coiled-coil domain AAA PF00004.29 EJS41363.1 - 4.8e-41 140.3 0.0 1.2e-40 139.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS41363.1 - 2.3e-08 33.7 0.3 2e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 EJS41363.1 - 1.1e-06 28.5 0.0 3.3e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EJS41363.1 - 5.5e-05 23.0 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EJS41363.1 - 0.00012 22.2 0.8 0.00027 21.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EJS41363.1 - 0.00022 21.5 0.3 0.035 14.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 EJS41363.1 - 0.0008 19.5 0.0 0.011 15.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 EJS41363.1 - 0.00081 18.8 0.1 1.2 8.5 0.0 2.7 1 1 1 2 2 2 2 Bacterial TniB protein AAA_18 PF13238.6 EJS41363.1 - 0.00091 19.8 0.0 0.00091 19.8 0.0 2.9 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 EJS41363.1 - 0.0011 18.2 0.0 0.0011 18.2 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EJS41363.1 - 0.0032 16.9 0.1 0.0086 15.5 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EJS41363.1 - 0.0032 17.4 0.1 0.02 14.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EJS41363.1 - 0.0042 16.8 0.2 0.017 14.8 0.0 2.1 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_16 PF13191.6 EJS41363.1 - 0.0043 17.5 0.0 0.073 13.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EJS41363.1 - 0.0098 15.5 0.0 0.57 9.7 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EJS41363.1 - 0.021 15.0 1.5 0.049 13.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 EJS41363.1 - 0.03 13.8 0.2 0.086 12.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 EJS41363.1 - 0.21 12.0 0.0 0.21 12.0 0.0 2.8 2 0 0 2 2 1 0 AAA domain VPS9 PF02204.18 EJS41365.1 - 2.8e-17 62.8 1.4 6.7e-17 61.6 1.4 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain polyprenyl_synt PF00348.17 EJS41366.1 - 7.3e-58 195.6 0.0 8.6e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3605 PF12239.8 EJS41368.1 - 1.9e-38 132.2 0.1 2.3e-38 131.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Arrestin_C PF02752.22 EJS41369.1 - 0.046 14.2 5.6 0.13 12.7 2.1 2.5 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain VPS28 PF03997.12 EJS41370.1 - 2.2e-72 242.7 4.3 2.5e-72 242.5 4.3 1.0 1 0 0 1 1 1 1 VPS28 protein DUF3114 PF11311.8 EJS41370.1 - 0.01 15.4 2.0 0.39 10.2 2.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3114) DUF3417 PF11897.8 EJS41370.1 - 0.011 16.2 0.2 0.022 15.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) BMFP PF04380.13 EJS41370.1 - 0.099 13.1 0.1 0.36 11.4 0.0 1.9 2 0 0 2 2 2 0 Membrane fusogenic activity Pro_isomerase PF00160.21 EJS41371.1 - 5.5e-08 33.2 0.1 1.1e-07 32.3 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3727 PF12527.8 EJS41371.1 - 5.1 7.4 7.9 0.2 11.9 0.9 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3727) Aldedh PF00171.22 EJS41372.1 - 4e-173 576.2 0.0 4.6e-173 576.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FliD_C PF07195.12 EJS41372.1 - 0.011 15.2 0.1 0.021 14.3 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus ABC2_membrane PF01061.24 EJS41373.1 - 1.8e-64 217.0 49.5 1e-35 123.1 11.6 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EJS41373.1 - 7e-36 123.8 0.0 2.7e-17 63.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EJS41373.1 - 1.3e-34 117.9 5.8 2e-28 98.1 0.1 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EJS41373.1 - 8.2e-10 39.2 0.0 1.7e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EJS41373.1 - 9.9e-07 28.8 0.0 9.2e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EJS41373.1 - 3.9e-05 24.1 0.1 0.0029 18.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EJS41373.1 - 8.8e-05 22.0 0.0 0.71 9.3 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EJS41373.1 - 0.0003 20.9 0.0 0.64 10.1 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 EJS41373.1 - 0.0014 17.8 11.4 0.0014 17.8 11.4 3.4 3 1 0 3 3 3 1 ABC-2 family transporter protein AAA_22 PF13401.6 EJS41373.1 - 0.0017 18.7 0.1 0.073 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EJS41373.1 - 0.0021 17.8 0.2 0.098 12.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EJS41373.1 - 0.0022 17.6 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EJS41373.1 - 0.0023 17.8 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EJS41373.1 - 0.0034 17.9 0.0 0.081 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EJS41373.1 - 0.0048 16.8 0.0 0.09 12.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EJS41373.1 - 0.016 14.9 0.3 0.88 9.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EJS41373.1 - 0.016 14.8 0.2 0.05 13.2 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EJS41373.1 - 0.038 14.4 0.0 2.1 8.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 EJS41373.1 - 0.04 13.2 0.0 0.76 9.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 EJS41373.1 - 0.042 13.9 0.2 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EJS41373.1 - 0.05 13.8 0.1 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EJS41373.1 - 0.11 12.4 0.1 12 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 EJS41373.1 - 0.12 12.2 0.0 14 5.5 0.0 3.3 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 EJS41373.1 - 0.17 12.4 0.0 0.49 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Gly_transf_sug PF04488.15 EJS41374.1 - 5.3e-24 84.7 0.0 1.2e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif zf-H2C2_2 PF13465.6 EJS41374.1 - 0.14 12.6 0.3 0.33 11.5 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger double domain Lge1 PF11488.8 EJS41375.1 - 2.4e-18 66.1 3.7 2.4e-18 66.1 3.7 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 zf-CCCH PF00642.24 EJS41376.1 - 1.3e-11 44.1 10.7 4.8e-06 26.3 3.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EJS41376.1 - 1.7e-11 43.7 18.6 7.3e-06 25.9 3.7 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EJS41376.1 - 4.4e-10 39.1 12.8 7.9e-06 25.6 4.6 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 EJS41376.1 - 4.7e-07 30.5 15.1 9.8e-05 23.0 0.4 3.2 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 EJS41376.1 - 0.00015 22.0 0.6 0.00035 20.7 0.6 1.8 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EJS41376.1 - 0.015 15.8 21.9 0.18 12.3 4.4 3.1 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Glyco_transf_15 PF01793.16 EJS41377.1 - 3e-132 440.8 12.3 3.8e-132 440.5 12.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5100 PF17029.5 EJS41377.1 - 0.12 12.2 1.8 0.85 9.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5100) ODC_AZ PF02100.17 EJS41378.1 - 0.00095 19.1 0.4 0.0016 18.4 0.1 1.5 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme Arf PF00025.21 EJS41379.1 - 6.2e-47 159.3 0.4 7.5e-47 159.0 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EJS41379.1 - 3.4e-15 56.0 0.0 4.2e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EJS41379.1 - 1e-12 47.8 0.1 1.3e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EJS41379.1 - 2.8e-12 46.9 0.0 4.2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EJS41379.1 - 8.1e-11 41.7 0.3 5.9e-06 25.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EJS41379.1 - 8e-08 31.9 0.1 9.9e-08 31.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJS41379.1 - 1.5e-07 31.5 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJS41379.1 - 1.7e-07 31.0 0.1 3.9e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EJS41379.1 - 0.0044 17.6 0.2 0.04 14.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EJS41379.1 - 0.038 14.2 0.0 0.14 12.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain TSNAXIP1_N PF15739.5 EJS41379.1 - 0.066 13.6 0.1 8.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus tRNA_lig_CPD PF08302.11 EJS41379.1 - 0.074 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Thymidylate_kin PF02223.17 EJS41379.1 - 0.092 12.4 0.1 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_23 PF13476.6 EJS41379.1 - 0.19 12.2 1.2 0.67 10.4 1.2 2.0 1 1 0 1 1 1 0 AAA domain CDC45 PF02724.14 EJS41380.1 - 5.1 5.3 13.4 8.6 4.5 0.1 2.3 2 0 0 2 2 2 0 CDC45-like protein EF1G PF00647.19 EJS41381.1 - 1.6e-46 156.7 0.2 2.9e-46 155.9 0.2 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EJS41381.1 - 4.2e-14 52.5 0.0 1.1e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EJS41381.1 - 8.3e-14 51.7 0.2 4.4e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJS41381.1 - 1.5e-05 24.9 0.2 3.1e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EJS41381.1 - 0.0015 18.7 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EJS41381.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Sgf11_N PF18519.1 EJS41382.1 - 4.6e-24 83.7 1.5 7e-24 83.1 1.5 1.3 1 0 0 1 1 1 1 SAGA-associated factor 11 N-terminal domain Sgf11 PF08209.11 EJS41382.1 - 1.2e-15 56.8 3.8 1.6e-15 56.4 3.8 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf_C2H2_13 PF18508.1 EJS41382.1 - 0.00068 19.2 0.8 0.00089 18.8 0.2 1.6 2 0 0 2 2 2 1 Zinc finger domain zf-C2HC_2 PF13913.6 EJS41382.1 - 0.0031 17.4 0.2 0.0041 17.0 0.2 1.2 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.8 EJS41382.1 - 0.0091 15.8 0.0 0.0091 15.8 0.0 1.1 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain zf_Rg PF17915.1 EJS41382.1 - 0.11 12.0 0.3 0.19 11.1 0.3 1.3 1 0 0 1 1 1 0 Reverse gyrase zinc finger Skp1_POZ PF03931.15 EJS41383.1 - 5.6e-18 64.9 0.3 9.2e-18 64.2 0.0 1.5 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Vps16_N PF04841.13 EJS41384.1 - 3.3e-122 408.2 0.3 5.8e-122 407.4 0.3 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EJS41384.1 - 5.2e-121 403.6 13.0 5.9e-121 403.4 12.0 1.6 2 0 0 2 2 2 1 Vps16, C-terminal region HTH_Tnp_IS630 PF01710.16 EJS41384.1 - 0.054 13.5 0.3 0.16 12.0 0.3 1.8 1 0 0 1 1 1 0 Transposase RRM_1 PF00076.22 EJS41385.1 - 6.4e-55 182.9 1.1 8e-19 67.2 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJS41385.1 - 1e-06 28.7 0.3 0.011 15.9 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif RRM_Rrp7 PF17799.1 EJS41385.1 - 0.014 15.2 0.2 3 7.6 0.0 3.1 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain FMN_dh PF01070.18 EJS41385.1 - 0.084 11.9 0.6 2.2 7.2 0.0 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Pkinase PF00069.25 EJS41386.1 - 2.1e-55 187.9 1.1 2e-54 184.7 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41386.1 - 1.8e-24 86.5 0.5 1.2e-23 83.7 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJS41386.1 - 0.027 13.4 0.2 0.042 12.8 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain tRNA-synt_1 PF00133.22 EJS41387.1 - 1.4e-150 502.5 0.1 1.9e-150 502.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EJS41387.1 - 2.5e-20 73.0 0.2 7.3e-20 71.5 0.2 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EJS41387.1 - 2.1e-18 66.3 6.1 1.1e-12 47.4 0.1 4.1 5 0 0 5 5 5 3 tRNA synthetases class I (M) Zn_Tnp_IS91 PF14319.6 EJS41387.1 - 0.28 11.2 1.7 0.69 10.0 1.7 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-C2H2 PF00096.26 EJS41388.1 - 1.2e-08 34.9 7.7 0.00086 19.6 0.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJS41388.1 - 1.1e-06 29.0 6.5 0.0075 17.0 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJS41388.1 - 0.014 15.7 2.2 1.6 9.1 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EJS41388.1 - 0.022 14.5 6.4 1 9.2 0.4 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type C1_4 PF07975.12 EJS41388.1 - 0.027 14.7 2.4 0.064 13.5 1.3 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain zf-H2C2_2 PF13465.6 EJS41388.1 - 0.028 14.8 3.3 0.12 12.8 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 EJS41388.1 - 0.044 14.5 0.8 0.75 10.5 0.2 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_3 PF13878.6 EJS41388.1 - 0.047 13.5 1.7 0.13 12.1 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Zn_ribbon_SprT PF17283.2 EJS41388.1 - 0.13 12.2 2.8 0.1 12.6 0.9 1.8 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 EJS41388.1 - 0.13 12.4 2.1 0.24 11.5 1.1 1.9 1 1 1 2 2 2 0 Zinc ribbon domain HypA PF01155.19 EJS41388.1 - 0.14 12.1 2.1 0.81 9.7 2.1 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-LYAR PF08790.11 EJS41388.1 - 0.16 11.9 2.4 6.6 6.7 0.2 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 EJS41388.1 - 0.18 11.4 2.7 3.9 7.2 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 EJS41388.1 - 0.2 12.4 2.5 0.35 11.7 2.5 1.4 1 0 0 1 1 1 0 zinc-ribbon family zf-C2H2_6 PF13912.6 EJS41388.1 - 0.33 11.0 0.3 0.33 11.0 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.21 EJS41388.1 - 0.48 10.6 6.3 1.6 8.9 6.3 1.8 1 1 0 1 1 1 0 FYVE zinc finger LIM PF00412.22 EJS41388.1 - 0.48 10.7 3.7 6.5 7.1 4.0 2.2 1 1 0 1 1 1 0 LIM domain NAC PF01849.18 EJS41389.1 - 1.3e-16 60.3 0.2 2.5e-16 59.4 0.2 1.5 1 0 0 1 1 1 1 NAC domain Glyco_hydro_20b PF02838.15 EJS41389.1 - 0.033 15.0 0.1 0.15 12.9 0.1 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 adh_short PF00106.25 EJS41390.1 - 2.3e-09 37.0 0.0 3.1e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase RRM_1 PF00076.22 EJS41391.1 - 4.2e-11 42.5 0.0 6.7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox_KN PF05920.11 EJS41392.1 - 6.2e-19 67.6 1.5 1.2e-18 66.7 1.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EJS41392.1 - 1.4e-05 24.8 0.7 3.3e-05 23.7 0.7 1.6 1 0 0 1 1 1 1 Homeodomain TFR_dimer PF04253.15 EJS41393.1 - 2e-23 82.8 0.0 3.5e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 EJS41393.1 - 0.06 13.4 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 PA domain Peptidase_M28 PF04389.17 EJS41393.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 UbiA PF01040.18 EJS41394.1 - 9.8e-49 165.9 9.4 1.5e-48 165.3 9.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Oxidored_FMN PF00724.20 EJS41395.1 - 2.2e-133 444.8 0.0 2.6e-133 444.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cyt-b5 PF00173.28 EJS41396.1 - 4.9e-15 55.4 0.0 6.3e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_9 PF18444.1 EJS41397.1 - 2.3e-32 110.6 0.4 4.7e-32 109.6 0.4 1.6 1 0 0 1 1 1 1 RNA recognition motif TAP_C PF03943.13 EJS41397.1 - 5e-14 51.7 0.2 1.7e-13 50.0 0.2 2.0 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 EJS41397.1 - 6.1e-07 29.1 2.1 1.2e-06 28.1 2.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EJS41397.1 - 4e-06 27.1 12.2 0.0002 21.7 2.2 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) DNA_pol_B PF00136.21 EJS41398.1 - 1.1e-112 377.1 1.9 2.3e-112 376.0 1.9 1.6 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EJS41398.1 - 5.8e-18 65.1 4.8 7.5e-09 35.2 1.2 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EJS41398.1 - 1.4e-10 41.5 9.5 3.9e-10 40.1 9.5 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Spectrin PF00435.21 EJS41398.1 - 0.068 13.7 1.2 0.29 11.6 1.2 2.2 1 0 0 1 1 1 0 Spectrin repeat SET PF00856.28 EJS41399.1 - 1.2e-13 51.7 0.8 7.5e-13 49.2 0.8 2.0 1 1 0 1 1 1 1 SET domain Ribosomal_L40e PF01020.17 EJS41399.1 - 0.02 14.8 2.3 0.051 13.5 2.3 1.7 1 0 0 1 1 1 0 Ribosomal L40e family AbiJ_NTD4 PF18863.1 EJS41399.1 - 0.076 13.5 0.3 0.16 12.4 0.3 1.6 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 YHS PF04945.13 EJS41399.1 - 0.089 12.9 0.4 0.28 11.3 0.4 1.8 1 0 0 1 1 1 0 YHS domain STIMATE PF12400.8 EJS41400.1 - 1.2e-44 151.9 8.2 2.3e-44 150.9 8.2 1.5 1 0 0 1 1 1 1 STIMATE family WRNPLPNID PF15017.6 EJS41401.1 - 0.15 13.0 3.6 0.35 11.8 3.6 1.6 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Cytomega_UL84 PF06284.11 EJS41401.1 - 0.39 9.1 1.2 0.57 8.6 1.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CENP-B_dimeris PF09026.10 EJS41401.1 - 1.9 8.9 6.8 8 6.9 6.5 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain tRNA-synt_1 PF00133.22 EJS41402.1 - 2.6e-42 144.9 0.1 9.8e-34 116.6 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EJS41402.1 - 9.4e-17 60.8 0.8 4.1e-09 35.7 0.0 4.2 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EJS41402.1 - 1.7e-13 50.8 0.0 5.3e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EJS41402.1 - 1.5e-06 27.8 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Methyltransf_15 PF09445.10 EJS41403.1 - 1.4e-66 223.2 0.0 1.9e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EJS41403.1 - 5.5e-07 29.5 0.0 8.3e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 EJS41403.1 - 3.5e-06 26.9 0.0 4.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS41403.1 - 1.4e-05 25.7 0.0 3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EJS41403.1 - 0.002 17.8 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_N4_Mtase PF01555.18 EJS41403.1 - 0.0091 15.7 0.1 0.73 9.5 0.0 2.3 1 1 1 2 2 2 2 DNA methylase MethyltransfD12 PF02086.15 EJS41403.1 - 0.03 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase CMAS PF02353.20 EJS41403.1 - 0.047 13.0 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EJS41403.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EJS41403.1 - 0.17 12.6 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.23 EJS41405.1 - 4.6e-105 351.5 0.0 5.6e-105 351.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EJS41405.1 - 1.2e-16 61.4 1.2 2.5e-14 53.9 1.2 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EJS41405.1 - 0.0026 18.3 0.0 0.77 10.4 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EJS41405.1 - 0.0033 18.0 0.0 0.38 11.3 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Pkinase PF00069.25 EJS41406.1 - 5e-80 268.7 0.0 9.4e-80 267.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41406.1 - 1.8e-37 129.1 0.0 3.6e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EJS41406.1 - 2.2e-28 98.4 1.1 1.2e-15 57.5 0.1 2.8 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 EJS41406.1 - 1.9e-10 40.9 0.0 7e-07 29.5 0.0 2.9 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 EJS41406.1 - 7.2e-07 28.8 0.0 1.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJS41406.1 - 3.6e-05 23.2 0.0 7.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJS41406.1 - 0.00012 22.0 1.5 0.012 15.6 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family FHA_2 PF17913.1 EJS41406.1 - 0.00035 20.8 0.3 4.4 7.6 0.0 3.6 3 0 0 3 3 3 1 FHA domain RIO1 PF01163.22 EJS41406.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family TMEM51 PF15345.6 EJS41406.1 - 0.69 9.7 6.7 26 4.5 5.2 2.5 2 0 0 2 2 2 0 Transmembrane protein 51 CPSF100_C PF13299.6 EJS41406.1 - 2.7 8.2 5.8 0.39 10.9 1.5 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PTPA PF03095.15 EJS41407.1 - 3e-114 381.5 1.0 3.5e-114 381.3 1.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein WD40 PF00400.32 EJS41408.1 - 1e-29 102.1 15.1 2.5e-05 25.0 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 EJS41408.1 - 6.2e-05 21.8 5.0 0.087 11.4 0.0 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EJS41408.1 - 8.4e-05 22.8 0.9 0.27 11.6 0.0 4.3 1 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EJS41408.1 - 0.014 14.1 0.1 1.7 7.3 0.0 3.4 1 1 2 3 3 3 0 Nup133 N terminal like ACPS PF01648.20 EJS41409.1 - 2e-20 73.0 0.0 3.1e-20 72.4 0.0 1.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EJS41409.1 - 0.15 12.2 0.0 0.93 9.7 0.0 2.0 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain ABC_membrane_2 PF06472.15 EJS41410.1 - 5.5e-89 298.1 2.8 5.5e-89 298.1 2.8 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EJS41410.1 - 6.5e-15 55.9 0.0 2.2e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EJS41410.1 - 0.00078 18.9 0.2 0.69 9.3 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EJS41410.1 - 0.037 14.4 0.1 0.098 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EJS41410.1 - 0.18 12.3 10.3 3.5 8.1 10.3 2.5 1 1 0 1 1 1 0 AAA domain Nop53 PF07767.11 EJS41411.1 - 7.8e-96 321.9 41.5 9.8e-96 321.6 41.5 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DivIC PF04977.15 EJS41411.1 - 0.11 12.3 3.1 0.68 9.7 1.7 2.9 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 EJS41411.1 - 0.43 11.2 6.4 5.4 7.7 0.1 3.2 3 0 0 3 3 3 0 SlyX CDC45 PF02724.14 EJS41411.1 - 1 7.6 16.9 1.9 6.7 16.9 1.4 1 0 0 1 1 1 0 CDC45-like protein Oxysterol_BP PF01237.18 EJS41412.1 - 7.1e-61 206.1 3.5 3.3e-58 197.3 3.5 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Pkinase PF00069.25 EJS41413.1 - 1.4e-60 204.9 0.0 2.6e-60 204.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41413.1 - 9.1e-38 130.0 0.0 1.7e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS41413.1 - 1.9e-08 34.0 0.0 4.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJS41413.1 - 0.0091 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EJS41413.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EJS41413.1 - 0.083 12.2 0.2 0.2 11.0 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1819 PF08849.11 EJS41413.1 - 0.14 12.0 0.5 0.64 9.8 0.1 2.1 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) PHD PF00628.29 EJS41414.1 - 4.9e-11 42.4 4.6 4.9e-11 42.4 4.6 2.5 3 0 0 3 3 3 1 PHD-finger DUF1383 PF07134.11 EJS41414.1 - 0.023 13.8 2.0 0.046 12.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1383) CxC6 PF18721.1 EJS41414.1 - 0.14 12.5 0.5 0.14 12.5 0.5 2.7 3 1 0 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases NifU_N PF01592.16 EJS41416.1 - 1.3e-57 193.5 0.0 1.6e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EJS41416.1 - 0.029 14.6 0.1 0.053 13.8 0.1 1.4 1 0 0 1 1 1 0 TSCPD domain Zn_clus PF00172.18 EJS41417.1 - 0.0013 18.8 11.2 0.0031 17.6 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CtaG_Cox11 PF04442.14 EJS41418.1 - 4.3e-61 205.4 0.0 6.9e-61 204.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF1891 PF09004.10 EJS41418.1 - 0.05 13.2 1.4 0.11 12.2 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) Ribosomal_L5e PF17144.4 EJS41419.1 - 1.4e-83 278.8 0.0 2.3e-83 278.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EJS41419.1 - 2.1e-31 108.7 0.9 2.1e-31 108.7 0.9 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 EJS41419.1 - 0.0079 16.6 0.4 0.024 15.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thr_synth_N PF14821.6 EJS41419.1 - 0.013 15.7 0.3 0.94 9.7 0.0 2.9 3 0 0 3 3 3 0 Threonine synthase N terminus NAC PF01849.18 EJS41419.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NAC domain Phage_holin_3_3 PF16083.5 EJS41419.1 - 0.11 12.7 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III DAG_kinase_N PF14513.6 EJS41419.1 - 0.14 12.4 1.0 0.22 11.7 0.1 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus TRF PF08558.10 EJS41421.1 - 4.4e-83 278.5 0.6 6.4e-83 278.0 0.6 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EJS41421.1 - 9.5e-09 35.3 1.6 4.7e-08 33.1 1.3 2.3 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJS41421.1 - 0.011 16.0 0.1 0.037 14.3 0.1 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Linker_histone PF00538.19 EJS41422.1 - 2.4e-47 159.2 11.4 7.5e-26 90.3 0.0 3.5 4 0 0 4 4 4 2 linker histone H1 and H5 family Dicty_REP PF05086.12 EJS41422.1 - 2.4 6.1 13.4 0.042 11.8 3.7 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.32 EJS41423.1 - 1e-06 29.3 5.2 0.004 18.0 0.2 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EJS41423.1 - 0.03 13.3 1.0 2.1 7.3 0.0 3.7 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Spc29 PF17082.5 EJS41424.1 - 1.8e-68 231.0 10.0 2.1e-68 230.8 10.0 1.0 1 0 0 1 1 1 1 Spindle Pole Component 29 Gal4_dimer PF03902.13 EJS41424.1 - 0.11 12.7 0.5 0.93 9.7 0.0 2.5 3 0 0 3 3 3 0 Gal4-like dimerisation domain Fib_alpha PF08702.10 EJS41424.1 - 0.16 12.1 1.7 0.4 10.9 0.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ribonuclease_T2 PF00445.18 EJS41425.1 - 1.5e-43 149.1 2.0 2.1e-43 148.7 2.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Tfb2 PF03849.14 EJS41426.1 - 4.7e-139 463.3 4.3 7.1e-139 462.7 4.3 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EJS41426.1 - 5.1e-22 78.1 0.5 1.9e-21 76.3 0.4 2.1 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EJS41426.1 - 7e-05 23.0 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mei5 PF10376.9 EJS41427.1 - 2.3e-38 132.2 20.1 2.7e-38 131.9 20.1 1.0 1 0 0 1 1 1 1 Double-strand recombination repair protein MafB19-deam PF14437.6 EJS41427.1 - 0.063 13.0 2.0 0.12 12.1 1.9 1.6 1 1 0 1 1 1 0 MafB19-like deaminase VPS38 PF17649.1 EJS41427.1 - 1.8 7.4 16.1 0.75 8.6 12.9 1.7 1 1 1 2 2 2 0 Vacuolar protein sorting 38 APG6 PF04111.12 EJS41428.1 - 2.1e-58 197.2 2.0 5.3e-58 195.9 2.0 1.7 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EJS41428.1 - 2.9e-25 89.3 26.6 2.9e-25 89.3 26.6 2.5 2 0 0 2 2 2 1 Apg6 coiled-coil region Mit_ribos_Mrp51 PF11709.8 EJS41429.1 - 6.7e-65 220.1 1.7 2.8e-62 211.4 1.7 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Csm1_B PF18211.1 EJS41429.1 - 0.068 13.0 0.2 0.15 12.0 0.2 1.6 1 0 0 1 1 1 0 Csm1 subunit domain B NUDIX PF00293.28 EJS41430.1 - 1.3e-31 109.3 0.1 2.3e-31 108.6 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain CymA PF16941.5 EJS41430.1 - 0.036 13.3 0.2 0.07 12.3 0.1 1.4 2 0 0 2 2 2 0 Putative cyclodextrin porin Hist_deacetyl PF00850.19 EJS41431.1 - 2.9e-51 174.8 0.1 5.2e-51 174.0 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain RhoGAP PF00620.27 EJS41432.1 - 2.2e-38 131.5 3.8 1e-37 129.3 0.1 3.0 3 0 0 3 3 3 1 RhoGAP domain PX PF00787.24 EJS41432.1 - 6.5e-09 35.8 0.0 2.3e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 PX domain PH PF00169.29 EJS41432.1 - 1.2e-08 35.4 0.1 3.9e-08 33.8 0.1 1.9 1 0 0 1 1 1 1 PH domain DUF1708 PF08101.11 EJS41432.1 - 0.0092 15.2 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF272 PF03312.15 EJS41432.1 - 0.098 12.9 0.2 0.46 10.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF272) ECH_2 PF16113.5 EJS41432.1 - 0.33 10.4 1.8 0.62 9.5 1.8 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase 2-Hacid_dh_C PF02826.19 EJS41433.1 - 1.5e-33 115.7 0.0 3e-33 114.7 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EJS41433.1 - 0.0042 16.8 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EJS41433.1 - 0.08 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EJS41433.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 EJS41433.1 - 0.16 11.6 0.1 0.38 10.4 0.1 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PEX11 PF05648.14 EJS41434.1 - 1.1e-08 34.8 4.7 2.6e-06 27.1 2.1 2.4 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Arginase PF00491.21 EJS41435.1 - 4.8e-76 255.9 0.0 5.8e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family GDPD PF03009.17 EJS41436.1 - 3.9e-89 298.8 0.1 7.3e-89 297.9 0.1 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EJS41436.1 - 3.9e-24 85.0 0.7 1.6e-09 38.2 0.0 4.4 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) SPX PF03105.19 EJS41436.1 - 2.3e-21 77.2 16.2 3.1e-11 43.8 0.2 3.6 1 1 2 3 3 3 3 SPX domain Ank_4 PF13637.6 EJS41436.1 - 2.5e-16 59.8 0.4 3.9e-06 27.3 0.3 5.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJS41436.1 - 8.6e-14 50.3 7.3 0.094 13.3 0.1 7.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EJS41436.1 - 3.1e-09 36.9 0.7 0.41 11.0 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EJS41436.1 - 4e-09 36.5 1.2 1.8 9.2 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Oxidored-like PF09791.9 EJS41437.1 - 8.6e-26 89.3 2.8 1.6e-25 88.5 2.8 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal HSP70 PF00012.20 EJS41438.1 - 4.9e-200 665.7 3.6 4.9e-200 665.7 3.6 2.2 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EJS41438.1 - 3.9e-11 42.3 0.1 1.6e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EJS41438.1 - 0.0026 18.2 0.4 0.14 12.6 0.3 3.3 2 1 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.16 EJS41438.1 - 0.046 13.4 0.2 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Trans_reg_C PF00486.28 EJS41438.1 - 0.079 13.1 0.0 0.39 10.8 0.0 2.2 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal NLE PF08154.12 EJS41438.1 - 0.14 12.7 0.2 0.56 10.8 0.0 2.2 2 0 0 2 2 2 0 NLE (NUC135) domain GYF PF02213.16 EJS41439.1 - 2.1e-16 59.3 0.0 3.9e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EJS41439.1 - 0.0017 18.1 0.1 0.01 15.6 0.1 2.2 2 0 0 2 2 2 1 GYF domain 2 tRNA-synt_2 PF00152.20 EJS41440.1 - 4.2e-100 334.9 0.3 5.6e-100 334.4 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EJS41440.1 - 7.2e-06 25.9 0.1 1.4e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EJS41440.1 - 0.00076 19.0 0.3 0.016 14.7 0.1 2.7 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) Mis12 PF05859.12 EJS41440.1 - 0.032 14.3 0.1 0.078 13.0 0.1 1.6 1 0 0 1 1 1 0 Mis12 protein tRNA-synt_2b PF00587.25 EJS41440.1 - 0.053 13.5 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Lactamase_B_2 PF12706.7 EJS41441.1 - 8.2e-30 103.8 0.0 1.2e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EJS41441.1 - 3.6e-11 43.2 0.0 7.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PAXNEB PF05625.11 EJS41442.1 - 4.1e-90 302.6 1.6 4.8e-90 302.4 1.6 1.1 1 0 0 1 1 1 1 PAXNEB protein GNAT_acetyltran PF12746.7 EJS41442.1 - 0.094 12.3 0.1 0.23 11.0 0.1 1.6 2 0 0 2 2 2 0 GNAT acetyltransferase CCDC24 PF15669.5 EJS41443.1 - 0.027 14.3 1.8 0.049 13.5 0.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family MCU PF04678.13 EJS41443.1 - 0.04 14.0 0.6 0.088 12.9 0.1 1.7 1 1 1 2 2 2 0 Mitochondrial calcium uniporter BRI3BP PF14965.6 EJS41443.1 - 0.048 13.2 0.0 0.086 12.3 0.0 1.4 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Romo1 PF10247.9 EJS41444.1 - 1.2e-27 96.1 10.0 1.5e-27 95.8 10.0 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 tRNA-synt_1b PF00579.25 EJS41445.1 - 3.9e-83 279.2 0.0 5.1e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EJS41445.1 - 0.0025 17.6 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain PIG-Y PF15159.6 EJS41446.1 - 0.15 13.0 12.1 0.39 11.7 12.1 1.6 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Rad4 PF03835.15 EJS41447.1 - 1.4e-11 44.2 0.1 2.8e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EJS41447.1 - 2.3e-08 34.5 0.0 4.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Desulfoferrod_N PF06397.12 EJS41447.1 - 0.051 13.2 0.6 0.051 13.2 0.6 1.9 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain PAW PF04721.17 EJS41447.1 - 0.19 11.5 1.2 0.32 10.8 1.2 1.4 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW IBR PF01485.21 EJS41447.1 - 4.4 7.6 8.2 0.48 10.7 1.6 2.6 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain Abhydrolase_1 PF00561.20 EJS41448.1 - 4e-25 88.9 0.0 5.2e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJS41448.1 - 1.5e-10 40.8 0.0 1e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJS41448.1 - 9.5e-06 26.4 0.0 1.5e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family ORC3_N PF07034.11 EJS41448.1 - 0.00029 20.0 0.0 0.00043 19.5 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Peptidase_S9 PF00326.21 EJS41448.1 - 0.0059 16.1 0.0 3.6 7.0 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF915 PF06028.11 EJS41448.1 - 0.024 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PAF-AH_p_II PF03403.13 EJS41448.1 - 0.11 10.9 0.1 12 4.3 0.0 2.2 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.14 EJS41448.1 - 0.16 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) NOG1_N PF17835.1 EJS41449.1 - 1.9e-49 167.7 3.2 1.1e-48 165.2 0.1 2.5 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EJS41449.1 - 9.4e-27 92.8 1.7 9.4e-27 92.8 1.7 2.1 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.14 EJS41449.1 - 6.1e-26 90.0 0.2 1.9e-25 88.4 0.2 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EJS41449.1 - 7.1e-16 58.3 0.0 1.8e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJS41449.1 - 1.7e-07 30.9 0.0 3.8e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 EJS41449.1 - 0.0021 17.4 0.1 0.0049 16.2 0.1 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EJS41449.1 - 0.0022 17.9 0.1 2.8 7.8 0.1 3.5 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 EJS41449.1 - 0.011 16.1 0.0 0.36 11.2 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 EJS41449.1 - 0.053 13.7 0.0 0.32 11.2 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EJS41449.1 - 0.27 11.3 4.2 4.4 7.3 0.0 3.3 3 1 1 4 4 4 0 Dynamin family AAA_23 PF13476.6 EJS41449.1 - 1.1 9.7 0.0 1.1 9.7 0.0 3.1 2 1 0 2 2 1 0 AAA domain SLAC1 PF03595.17 EJS41450.1 - 1.1e-74 251.6 31.0 1.3e-74 251.4 31.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Pyr_redox_2 PF07992.14 EJS41451.1 - 1.1e-61 208.6 0.6 1.7e-61 208.1 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EJS41451.1 - 3.8e-35 120.5 0.6 4e-34 117.2 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EJS41451.1 - 1.9e-19 70.0 8.3 1.6e-18 67.0 1.9 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJS41451.1 - 1e-13 51.2 8.3 1.5e-12 47.4 8.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EJS41451.1 - 2.4e-08 33.8 1.0 5.4e-08 32.6 0.0 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EJS41451.1 - 1.9e-06 27.3 0.0 3.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EJS41451.1 - 6.3e-06 25.6 0.4 0.041 13.2 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EJS41451.1 - 2.9e-05 23.0 8.1 0.045 12.5 0.5 3.8 2 1 2 4 4 4 2 HI0933-like protein GIDA PF01134.22 EJS41451.1 - 0.00012 21.4 0.4 0.00012 21.4 0.4 3.2 2 1 1 3 3 3 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 EJS41451.1 - 0.0017 17.7 0.7 1.2 8.4 0.0 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EJS41451.1 - 0.0023 17.8 2.9 0.006 16.5 0.1 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EJS41451.1 - 0.0065 16.9 0.4 2.2 8.7 0.0 2.9 3 1 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EJS41451.1 - 0.0068 15.7 0.7 1.7 7.8 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EJS41451.1 - 0.024 14.2 7.5 0.028 14.0 0.2 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase TPR_22 PF18833.1 EJS41451.1 - 0.042 14.0 0.4 0.087 13.0 0.4 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat NAD_binding_8 PF13450.6 EJS41451.1 - 0.057 13.7 0.9 0.057 13.7 0.9 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EJS41451.1 - 0.063 12.5 1.6 0.12 11.6 0.2 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 EJS41451.1 - 6.5 5.7 12.4 0.042 12.9 2.3 2.4 4 0 0 4 4 4 0 FAD binding domain RIBIOP_C PF04950.12 EJS41452.1 - 3.5e-86 289.2 0.5 3.5e-86 289.2 0.5 2.9 2 1 1 3 3 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EJS41452.1 - 9.7e-29 99.3 0.0 4e-28 97.3 0.0 2.2 2 0 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 EJS41452.1 - 4.7e-06 26.3 1.0 0.0016 18.0 0.0 2.9 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EJS41452.1 - 2e-05 25.0 0.0 5.7e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EJS41452.1 - 2.4e-05 24.5 0.0 0.00013 22.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJS41452.1 - 6.8e-05 23.3 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJS41452.1 - 0.0011 19.2 0.1 0.0038 17.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 EJS41452.1 - 0.0028 17.7 0.2 0.011 15.8 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 EJS41452.1 - 0.0047 16.9 0.3 0.017 15.1 0.3 1.9 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 EJS41452.1 - 0.0048 17.4 0.0 0.0048 17.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 EJS41452.1 - 0.0068 16.8 0.2 0.017 15.5 0.2 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EJS41452.1 - 0.0071 15.6 0.9 0.013 14.7 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.22 EJS41452.1 - 0.0084 16.5 0.0 0.028 14.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 EJS41452.1 - 0.0099 16.1 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EJS41452.1 - 0.01 15.7 0.2 0.01 15.7 0.2 3.8 3 1 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 EJS41452.1 - 0.012 14.9 1.2 0.19 11.0 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.6 EJS41452.1 - 0.013 15.3 1.9 0.014 15.2 0.1 2.0 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 EJS41452.1 - 0.021 15.4 0.0 0.021 15.4 0.0 2.4 3 0 0 3 3 1 0 ABC transporter cobW PF02492.19 EJS41452.1 - 0.021 14.4 0.1 0.048 13.2 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EJS41452.1 - 0.035 14.1 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EJS41452.1 - 0.051 13.1 0.1 0.051 13.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EJS41452.1 - 0.056 13.4 0.4 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 NTPase MobB PF03205.14 EJS41452.1 - 0.059 13.3 1.4 0.11 12.4 0.2 2.1 2 1 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 EJS41452.1 - 0.068 12.9 0.1 1.7 8.4 0.1 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EJS41452.1 - 1.8 8.3 4.3 0.36 10.6 0.1 2.0 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 EJS41452.1 - 1.9 8.9 11.6 0.79 10.1 0.1 4.1 4 0 0 4 4 2 0 AAA domain Ubiq_cyt_C_chap PF03981.12 EJS41453.1 - 2.7e-41 141.0 0.2 4.7e-41 140.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HK PF02110.15 EJS41454.1 - 5.9e-98 327.1 0.1 1.1e-97 326.3 0.1 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EJS41454.1 - 3.4e-58 195.9 0.0 4.9e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase LRR_9 PF14580.6 EJS41455.1 - 1.9e-14 53.5 1.6 1.9e-14 53.5 1.6 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EJS41455.1 - 0.14 12.6 13.5 0.95 10.0 2.7 4.5 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) UPF0113_N PF17833.1 EJS41456.1 - 1.8e-28 98.9 0.0 2.7e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EJS41456.1 - 1.3e-24 86.2 0.0 2.4e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain SRP72 PF08492.12 EJS41457.1 - 1.2e-13 51.3 3.9 1.2e-13 51.3 3.9 2.5 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_12 PF13424.6 EJS41457.1 - 1.3e-06 28.6 3.3 0.0047 17.2 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EJS41457.1 - 2.1e-06 27.7 15.4 1e-05 25.5 6.0 3.9 3 2 1 4 4 4 1 Putative TPR-like repeat TPR_2 PF07719.17 EJS41457.1 - 2.2e-06 27.3 10.4 0.0099 15.9 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJS41457.1 - 0.00022 21.7 1.2 0.028 14.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EJS41457.1 - 0.00034 20.8 4.6 5.1 7.4 0.1 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EJS41457.1 - 0.01 16.6 0.1 16 6.6 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJS41457.1 - 0.014 15.6 7.0 0.19 12.1 0.2 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EJS41457.1 - 0.018 14.9 2.5 1 9.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EJS41457.1 - 0.047 13.1 0.5 0.3 10.4 0.0 2.3 2 0 0 2 2 2 0 MalT-like TPR region Clathrin PF00637.20 EJS41457.1 - 0.087 12.7 12.2 0.63 9.9 0.6 4.3 2 2 2 4 4 4 0 Region in Clathrin and VPS Mad3_BUB1_I PF08311.12 EJS41457.1 - 0.11 12.5 6.6 0.79 9.7 0.0 3.6 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 MIT PF04212.18 EJS41457.1 - 0.17 12.0 7.2 0.56 10.3 0.1 3.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EJS41457.1 - 0.22 11.4 0.2 0.22 11.4 0.2 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EJS41457.1 - 0.69 10.1 5.8 0.65 10.2 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EJS41457.1 - 1.4 9.7 6.1 59 4.6 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat Pkinase PF00069.25 EJS41458.1 - 9.3e-75 251.4 0.1 1.2e-74 251.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41458.1 - 3.6e-46 157.6 0.0 4.7e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS41458.1 - 2.5e-05 23.7 0.0 0.00049 19.5 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EJS41458.1 - 0.0079 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EJS41458.1 - 0.011 15.4 0.3 0.88 9.2 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EJS41458.1 - 0.041 12.6 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SET PF00856.28 EJS41459.1 - 3e-06 27.7 0.0 1.2e-05 25.8 0.0 2.0 1 1 0 1 1 1 1 SET domain Wyosine_form PF08608.12 EJS41460.1 - 6.6e-23 80.8 0.0 1.6e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EJS41460.1 - 1.4e-22 80.8 0.0 3.4e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 EJS41460.1 - 8.8e-17 61.6 0.0 1.7e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin GDPD PF03009.17 EJS41461.1 - 3.1e-41 141.8 0.0 3.7e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EJS41461.1 - 0.053 14.0 0.3 0.28 11.7 0.1 2.4 2 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Pkinase PF00069.25 EJS41462.1 - 1.1e-23 83.9 0.0 1.9e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41462.1 - 1.3e-13 50.9 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJS41462.1 - 3.1e-08 32.8 0.0 3.1e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EJS41462.1 - 0.027 14.4 1.2 0.083 12.8 0.0 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 EJS41463.1 - 3.1e-73 246.4 0.3 4.3e-73 245.9 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41463.1 - 2.6e-40 138.3 0.0 4.3e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS41463.1 - 3.1e-06 26.7 1.5 1.9e-05 24.2 1.5 2.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EJS41463.1 - 0.013 14.4 3.1 0.029 13.3 3.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EJS41463.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 EJS41463.1 - 1.2 8.7 5.5 1.8 8.0 0.0 2.7 1 1 1 3 3 3 0 PhoP regulatory network protein YrbL TFIIA PF03153.13 EJS41463.1 - 2.2 8.2 13.7 2.7 7.9 13.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EJS41463.1 - 2.9 8.5 9.9 1.2 9.8 7.0 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3387 PF11867.8 EJS41465.1 - 0.013 14.9 0.4 0.015 14.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) THP2 PF09432.10 EJS41465.1 - 0.23 11.5 9.4 0.92 9.6 3.6 2.4 1 1 1 2 2 2 0 Tho complex subunit THP2 DUF1771 PF08590.10 EJS41466.1 - 3.1e-18 65.9 7.8 5.1e-18 65.2 7.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EJS41466.1 - 3.4e-12 46.6 1.0 4.9e-12 46.0 0.1 1.7 2 0 0 2 2 2 1 Smr domain TLD PF07534.16 EJS41467.1 - 1.9e-28 99.5 0.0 5.3e-28 98.0 0.0 1.8 1 1 0 1 1 1 1 TLD Rad9 PF04139.13 EJS41468.1 - 1.2e-11 44.6 0.7 3.9e-05 23.2 0.1 2.4 2 0 0 2 2 2 2 Rad9 NUFIP1 PF10453.9 EJS41469.1 - 9.1e-19 67.1 0.4 2.1e-18 65.9 0.4 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) MINDY_DUB PF04424.13 EJS41470.1 - 1.9e-31 108.5 1.5 2.8e-31 107.9 0.5 1.8 2 0 0 2 2 2 1 MINDY deubiquitinase Atg14 PF10186.9 EJS41470.1 - 2.5 7.1 10.1 4.4 6.3 10.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RRM_1 PF00076.22 EJS41471.1 - 1.3e-10 40.9 0.5 3.2e-10 39.7 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJS41471.1 - 0.0018 17.8 0.0 0.0073 15.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MBOAT PF03062.19 EJS41472.1 - 6.6e-83 278.9 24.4 6.6e-83 278.9 24.4 2.2 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family NAD_kinase PF01513.21 EJS41473.1 - 4.1e-51 173.9 0.0 5.3e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EJS41473.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain AMPK1_CBM PF16561.5 EJS41474.1 - 0.011 15.9 0.9 0.011 15.9 0.9 2.5 3 1 0 3 3 3 0 Glycogen recognition site of AMP-activated protein kinase DUF5484 PF17583.2 EJS41474.1 - 0.086 12.5 0.5 0.33 10.6 0.5 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5484) Ribosomal_L36 PF00444.18 EJS41475.1 - 8.1e-20 70.7 8.3 1.1e-19 70.3 8.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.17 EJS41475.1 - 0.053 13.4 1.1 0.075 12.9 1.1 1.2 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family WD40 PF00400.32 EJS41476.1 - 3.2e-14 53.1 24.4 1.1e-06 29.2 0.2 9.1 11 0 0 11 11 11 4 WD domain, G-beta repeat YmzC PF14157.6 EJS41476.1 - 0.035 14.2 0.1 12 6.1 0.1 2.9 2 0 0 2 2 2 0 YmzC-like protein PHD PF00628.29 EJS41477.1 - 5e-12 45.5 8.6 8.8e-12 44.7 8.6 1.4 1 0 0 1 1 1 1 PHD-finger SLBP_RNA_bind PF15247.6 EJS41477.1 - 0.026 14.7 0.4 0.12 12.5 0.4 2.2 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain PHD_2 PF13831.6 EJS41477.1 - 0.78 9.4 4.5 1.2 8.7 4.5 1.3 1 0 0 1 1 1 0 PHD-finger TCO89 PF10452.9 EJS41478.1 - 7.4e-119 398.4 61.1 1.9e-118 397.1 61.1 1.7 1 1 0 1 1 1 1 TORC1 subunit TCO89 Metallophos PF00149.28 EJS41479.1 - 3.4e-38 132.2 0.1 5.8e-38 131.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EJS41479.1 - 1.7e-17 63.6 0.1 3.1e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ank_2 PF12796.7 EJS41480.1 - 1.9e-22 79.6 1.5 3.7e-14 53.1 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJS41480.1 - 1.6e-16 60.4 0.2 1.7e-11 44.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJS41480.1 - 1.3e-13 50.9 0.4 1.1e-07 32.0 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJS41480.1 - 4.1e-11 42.1 0.0 9.8e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EJS41480.1 - 4.4e-11 42.7 0.1 2e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat eIF-5_eIF-2B PF01873.17 EJS41481.1 - 3.3e-38 130.1 0.1 5.7e-38 129.4 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.15 EJS41481.1 - 0.00063 19.5 0.1 0.015 15.1 0.0 2.9 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region TF_Zn_Ribbon PF08271.12 EJS41481.1 - 0.025 14.1 0.2 0.048 13.2 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF35_N PF12172.8 EJS41481.1 - 0.1 12.5 0.2 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pkinase PF00069.25 EJS41482.1 - 4.9e-34 117.9 0.0 5.7e-24 84.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41482.1 - 1.2e-17 64.0 0.0 2.7e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase TIP49 PF06068.13 EJS41483.1 - 4.4e-158 526.1 1.6 6e-158 525.6 1.6 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EJS41483.1 - 7.5e-27 93.3 1.1 2.4e-26 91.7 0.9 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EJS41483.1 - 1.1e-08 35.6 0.7 2.2e-05 24.9 0.1 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EJS41483.1 - 3.3e-07 30.2 0.3 0.0018 18.0 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EJS41483.1 - 3.2e-05 23.4 1.8 3.6e-05 23.2 0.2 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EJS41483.1 - 3.8e-05 24.1 0.2 0.00016 22.1 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJS41483.1 - 0.0023 18.2 0.1 0.3 11.3 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EJS41483.1 - 0.003 17.9 1.9 0.0094 16.3 0.4 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EJS41483.1 - 0.015 15.3 0.2 3.9 7.5 0.0 2.9 2 2 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EJS41483.1 - 0.019 14.3 0.7 0.45 9.9 0.2 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EJS41483.1 - 0.025 14.1 0.9 0.06 12.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EJS41483.1 - 0.046 13.4 0.0 8.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 EJS41483.1 - 0.053 13.8 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 AAA domain CBFD_NFYB_HMF PF00808.23 EJS41483.1 - 0.073 13.4 0.2 0.26 11.6 0.2 2.0 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AAA_7 PF12775.7 EJS41483.1 - 0.22 11.0 0.8 0.79 9.2 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region ATP-synt_C PF00137.21 EJS41484.1 - 1.8e-32 111.5 30.6 1e-18 67.4 7.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Mis14 PF08641.12 EJS41485.1 - 4.3e-39 133.9 8.9 4.3e-39 133.9 8.9 1.9 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Syntaxin PF00804.25 EJS41486.1 - 4.8e-21 75.4 19.2 5e-21 75.3 17.4 1.9 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 EJS41486.1 - 3.2e-15 55.8 1.8 3.2e-15 55.8 1.8 2.2 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.21 EJS41486.1 - 8.1e-05 22.3 1.8 8.1e-05 22.3 1.8 2.4 2 0 0 2 2 2 1 Synaptobrevin DUF2207 PF09972.9 EJS41486.1 - 0.0054 15.6 0.8 0.009 14.8 0.0 1.6 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) Baculo_PEP_C PF04513.12 EJS41486.1 - 0.0066 16.5 3.4 0.2 11.7 0.1 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2277 PF10041.9 EJS41486.1 - 0.0077 16.5 1.0 2.2 8.7 1.1 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2277) AATase PF07247.12 EJS41486.1 - 0.017 13.7 0.9 0.017 13.7 0.9 2.0 1 1 0 2 2 2 0 Alcohol acetyltransferase BLOC1_2 PF10046.9 EJS41486.1 - 0.022 15.0 4.9 2.7 8.4 0.9 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Collectrin PF16959.5 EJS41486.1 - 0.022 14.5 1.0 0.063 13.0 1.0 1.8 1 0 0 1 1 1 0 Renal amino acid transporter T2SSF PF00482.23 EJS41486.1 - 0.084 12.8 1.3 0.28 11.1 1.3 1.9 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Allexi_40kDa PF05549.11 EJS41486.1 - 0.14 11.7 6.7 0.21 11.0 0.7 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein 7tm_7 PF08395.12 EJS41486.1 - 0.28 10.3 1.5 3.8 6.6 0.1 2.7 3 0 0 3 3 3 0 7tm Chemosensory receptor DASH_Dam1 PF08653.10 EJS41486.1 - 0.67 9.8 4.4 2.2 8.2 0.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 PBP1_TM PF14812.6 EJS41486.1 - 2.4 8.6 8.1 0.18 12.2 0.4 2.5 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2116 PF09889.9 EJS41486.1 - 6.4 6.8 5.7 1.4 8.9 1.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SlyX PF04102.12 EJS41486.1 - 6.9 7.4 9.6 0.7 10.6 2.3 2.7 2 1 0 2 2 2 0 SlyX Orf78 PF06024.12 EJS41486.1 - 7.7 6.9 7.6 0.7 10.2 0.4 2.6 2 1 0 2 2 2 0 Orf78 (ac78) Fas_alpha_ACP PF18325.1 EJS41487.1 - 1.4e-71 240.0 0.0 4.2e-71 238.5 0.0 1.9 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 EJS41487.1 - 9e-70 234.4 0.2 2e-69 233.3 0.2 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 EJS41487.1 - 1.8e-20 73.6 0.0 3.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EJS41487.1 - 8.8e-17 61.3 0.0 2.3e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EJS41487.1 - 5.1e-13 49.1 0.0 2.1e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EJS41487.1 - 0.0012 18.7 0.0 0.0036 17.2 0.0 1.8 1 0 0 1 1 1 1 KR domain SPG4 PF17325.2 EJS41487.1 - 0.035 15.2 0.2 0.13 13.3 0.2 1.9 1 0 0 1 1 1 0 Stationary phase protein 4 mRNA_triPase PF02940.15 EJS41489.1 - 5.7e-67 225.6 0.5 5.7e-67 225.6 0.5 1.6 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Glycos_transf_2 PF00535.26 EJS41490.1 - 1.7e-25 89.8 0.0 2.3e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EJS41490.1 - 3.7e-06 26.6 0.0 4.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 EJS41490.1 - 0.00051 20.0 0.0 0.00073 19.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EJS41490.1 - 0.01 16.3 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 ABC_tran PF00005.27 EJS41491.1 - 9.7e-48 162.2 0.0 9.7e-25 87.7 0.0 3.9 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EJS41491.1 - 7.9e-13 48.3 0.0 0.00061 19.3 0.0 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJS41491.1 - 2.7e-12 47.1 6.4 0.012 15.4 0.0 4.6 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system Chromo PF00385.24 EJS41491.1 - 4e-10 39.4 1.3 9.9e-10 38.2 1.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 EJS41491.1 - 9.8e-07 28.4 0.1 0.074 12.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EJS41491.1 - 2e-06 27.8 0.0 0.051 13.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EJS41491.1 - 3.5e-06 27.7 8.5 0.013 16.0 0.0 3.6 4 0 0 4 4 2 2 AAA domain RsgA_GTPase PF03193.16 EJS41491.1 - 3.8e-06 26.9 0.0 0.049 13.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EJS41491.1 - 3.7e-05 24.0 0.0 0.6 10.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EJS41491.1 - 0.00036 20.9 0.1 4.2 7.8 0.0 3.6 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.6 EJS41491.1 - 0.001 19.6 0.4 1.8 9.1 0.0 3.3 4 0 0 4 4 2 1 AAA domain MeaB PF03308.16 EJS41491.1 - 0.0012 17.9 0.6 0.9 8.5 0.0 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EJS41491.1 - 0.0023 18.1 1.2 0.76 9.8 0.1 3.7 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_28 PF13521.6 EJS41491.1 - 0.0028 17.9 0.0 3 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJS41491.1 - 0.003 18.0 0.0 0.63 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EJS41491.1 - 0.0045 16.7 0.2 7.1 6.3 0.3 3.4 3 1 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EJS41491.1 - 0.0046 17.1 0.0 5.2 7.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EJS41491.1 - 0.0066 16.9 0.0 5.7 7.4 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EJS41491.1 - 0.0096 15.7 7.6 1.1 8.8 0.1 3.8 3 1 0 3 3 2 2 AAA ATPase domain AAA_27 PF13514.6 EJS41491.1 - 0.011 15.4 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EJS41491.1 - 0.017 15.1 0.0 2.6 8.0 0.0 3.0 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 EJS41491.1 - 0.057 12.6 0.1 9 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MukB PF04310.12 EJS41491.1 - 0.061 13.1 0.1 7.7 6.3 0.0 2.6 3 0 0 3 3 2 0 MukB N-terminal Dynamin_N PF00350.23 EJS41491.1 - 0.064 13.3 0.0 6.1 6.9 0.0 3.0 2 1 0 2 2 2 0 Dynamin family Roc PF08477.13 EJS41491.1 - 0.069 13.4 0.0 21 5.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EJS41491.1 - 0.072 12.8 0.2 5.7 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain CLP1_P PF16575.5 EJS41491.1 - 0.094 12.5 0.1 7.4 6.3 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Thymidylate_kin PF02223.17 EJS41491.1 - 0.1 12.2 0.3 1.2 8.8 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase AAA_13 PF13166.6 EJS41491.1 - 0.11 11.1 3.4 1.3 7.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EJS41491.1 - 0.12 11.6 0.2 20 4.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin FtsH_ext PF06480.15 EJS41491.1 - 0.17 12.2 4.1 0.48 10.8 4.1 1.7 1 0 0 1 1 1 0 FtsH Extracellular Polysacc_synt_4 PF04669.13 EJS41492.1 - 2.1e-18 66.6 1.7 1e-16 61.0 1.7 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis SPT2 PF08243.11 EJS41493.1 - 5.3 7.6 15.2 8.1 7.0 5.8 2.2 2 0 0 2 2 2 0 SPT2 chromatin protein UPF0061 PF02696.14 EJS41494.1 - 3.5e-163 543.7 0.0 4.4e-163 543.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family SAGA-Tad1 PF12767.7 EJS41495.1 - 1.7e-78 263.6 0.2 3.7e-78 262.5 0.1 1.6 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 EJS41495.1 - 0.00041 20.2 0.0 0.00078 19.3 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF2722 PF10846.8 EJS41495.1 - 0.64 8.9 6.3 1.2 8.0 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Microtub_bd PF16796.5 EJS41496.1 - 6.8e-24 84.5 4.0 6.8e-24 84.5 4.0 3.2 2 2 0 2 2 2 1 Microtubule binding AKNA PF12443.8 EJS41496.1 - 0.0078 16.8 1.1 0.0078 16.8 1.1 3.7 3 1 1 4 4 4 1 AT-hook-containing transcription factor DUF3287 PF11690.8 EJS41496.1 - 0.08 12.7 6.4 1.7 8.4 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) zf-C2H2_9 PF16293.5 EJS41496.1 - 0.12 12.3 0.6 13 5.7 0.0 3.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) PilJ PF13675.6 EJS41496.1 - 0.85 9.7 3.6 12 5.9 1.0 3.0 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Methyltransf_12 PF08242.12 EJS41496.1 - 2.9 8.7 5.6 25 5.7 0.3 3.2 2 1 0 3 3 3 0 Methyltransferase domain DUF1843 PF08898.10 EJS41496.1 - 3.8 8.1 5.8 2.5 8.7 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF4407 PF14362.6 EJS41496.1 - 7.5 5.8 16.5 33 3.7 15.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fungal_trans PF04082.18 EJS41498.1 - 1.3e-19 70.3 8.8 3.5e-19 68.9 8.8 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 EJS41498.1 - 7.6e-11 42.0 1.4 2.2e-10 40.6 1.4 1.8 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.18 EJS41498.1 - 6.5e-08 32.6 18.9 1.1e-07 31.9 18.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 EJS41499.1 - 5.6e-10 39.7 10.8 0.00038 21.2 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Rhomboid PF01694.22 EJS41500.1 - 2.1e-23 83.0 8.5 2.1e-23 83.0 8.5 1.4 2 0 0 2 2 2 1 Rhomboid family DUF2075 PF09848.9 EJS41501.1 - 4e-112 375.0 0.0 4.8e-112 374.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EJS41501.1 - 8.3e-07 29.4 0.0 2.7e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EJS41501.1 - 0.00028 21.3 0.0 0.00056 20.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) VirE PF05272.11 EJS41501.1 - 0.00078 19.2 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Virulence-associated protein E RNA_helicase PF00910.22 EJS41501.1 - 0.0031 17.9 0.2 0.5 10.8 0.0 3.2 2 1 1 3 3 3 1 RNA helicase AAA_30 PF13604.6 EJS41501.1 - 0.0033 17.2 0.0 0.031 14.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EJS41501.1 - 0.0043 17.1 0.0 2.3 8.2 0.1 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EJS41501.1 - 0.0045 17.4 0.0 0.0095 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EJS41501.1 - 0.012 15.9 0.0 0.04 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EJS41501.1 - 0.013 15.6 0.0 0.037 14.1 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF3466 PF11949.8 EJS41501.1 - 0.037 12.6 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) AAA_11 PF13086.6 EJS41501.1 - 0.051 13.4 0.0 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EJS41501.1 - 0.051 12.6 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EJS41501.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EJS41501.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain PIF1 PF05970.14 EJS41501.1 - 0.066 12.4 0.0 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase Bac_DnaA PF00308.18 EJS41501.1 - 0.086 12.7 0.3 2.7 7.8 0.4 2.7 2 0 0 2 2 2 0 Bacterial dnaA protein NB-ARC PF00931.22 EJS41501.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 EJS41501.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EJS41501.1 - 0.12 12.1 0.0 0.38 10.4 0.0 1.9 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UAA PF08449.11 EJS41502.1 - 6e-42 143.9 15.0 6.8e-42 143.7 15.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EJS41502.1 - 3e-08 33.9 22.4 7.6e-07 29.4 9.6 2.9 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EJS41502.1 - 1.1e-06 28.3 16.2 0.0035 16.7 2.9 2.9 2 1 1 3 3 3 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 EJS41502.1 - 0.013 14.7 7.8 0.15 11.2 0.9 2.2 1 1 1 2 2 2 0 Nucleotide-sugar transporter Orf78 PF06024.12 EJS41502.1 - 0.13 12.5 0.8 0.93 9.8 0.0 2.6 2 1 0 2 2 2 0 Orf78 (ac78) DUF2681 PF10883.8 EJS41502.1 - 0.88 10.0 4.3 3.3 8.2 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) DUF2189 PF09955.9 EJS41502.1 - 4.3 7.6 13.3 0.081 13.2 1.0 3.0 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2189) SRP68 PF16969.5 EJS41503.1 - 2.5e-63 214.9 15.1 3.9e-63 214.3 15.1 1.2 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 ATP-synt_Eps PF04627.13 EJS41504.1 - 9.3e-18 64.0 2.9 1.1e-17 63.8 2.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PI-PLC-X PF00388.19 EJS41505.1 - 3.5e-51 172.6 1.5 5e-51 172.1 0.2 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EJS41505.1 - 8.4e-38 129.3 0.1 2.6e-37 127.7 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 EJS41505.1 - 8.3e-06 26.2 0.2 2.2e-05 24.8 0.2 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.6 EJS41505.1 - 6.8e-05 23.2 2.9 0.0091 16.4 0.2 2.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EJS41505.1 - 0.00039 19.8 1.2 0.0047 16.4 0.3 2.8 2 0 0 2 2 2 1 EF hand C2 PF00168.30 EJS41505.1 - 0.0026 18.0 0.0 0.0077 16.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 EJS41505.1 - 0.02 14.8 2.1 0.12 12.3 0.5 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.6 EJS41505.1 - 0.15 11.9 2.4 0.24 11.3 1.3 2.0 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 EJS41505.1 - 0.56 9.8 3.0 0.83 9.3 0.2 2.6 2 0 0 2 2 2 0 EF hand RrnaAD PF00398.20 EJS41507.1 - 3.9e-79 265.5 0.0 4.6e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EJS41507.1 - 2.9e-07 31.1 0.0 6.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJS41507.1 - 1.6e-05 25.5 0.0 3.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EJS41507.1 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 EJS41507.1 - 0.00038 20.3 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.20 EJS41507.1 - 0.0014 18.0 0.0 0.0031 16.8 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EJS41507.1 - 0.0021 17.9 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AAA_lid_4 PF17864.1 EJS41507.1 - 0.0058 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 RuvB AAA lid domain Methyltransf_12 PF08242.12 EJS41507.1 - 0.006 17.3 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EJS41507.1 - 0.0083 16.0 0.1 0.34 10.7 0.0 2.3 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase MTS PF05175.14 EJS41507.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EJS41507.1 - 0.062 13.2 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_28 PF02636.17 EJS41507.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 EJS41507.1 - 0.093 12.0 0.1 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EJS41507.1 - 0.11 11.7 0.1 0.22 10.8 0.0 1.4 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_31 PF13847.6 EJS41507.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AA_permease PF00324.21 EJS41508.1 - 1.3e-124 416.5 42.9 1.6e-124 416.2 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS41508.1 - 1.7e-33 116.1 43.2 2.3e-33 115.6 43.2 1.2 1 0 0 1 1 1 1 Amino acid permease EamA PF00892.20 EJS41509.1 - 5.6e-27 94.6 29.8 1.8e-16 60.5 7.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EJS41509.1 - 2e-05 24.1 4.1 2e-05 24.1 4.1 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family Kelch_4 PF13418.6 EJS41510.1 - 4.5e-31 106.6 2.7 4.5e-07 29.8 0.3 6.7 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EJS41510.1 - 1.7e-30 104.7 1.2 1.5e-08 34.7 0.1 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.6 EJS41510.1 - 8.9e-20 70.6 0.4 8.9e-20 70.6 0.4 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 EJS41510.1 - 2.9e-16 59.1 7.7 4.2e-06 26.9 0.2 6.4 4 2 2 6 6 6 3 Kelch motif Kelch_5 PF13854.6 EJS41510.1 - 7.3e-13 48.2 6.0 0.026 14.5 0.2 6.3 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EJS41510.1 - 1.4e-12 47.0 2.8 7.2e-05 22.3 0.1 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EJS41510.1 - 1.1e-11 44.3 8.6 0.00024 21.0 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Lyase_1 PF00206.20 EJS41511.1 - 1.3e-120 402.6 0.0 2e-120 401.9 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EJS41511.1 - 6.1e-25 87.4 0.1 1.7e-24 86.0 0.1 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.12 EJS41511.1 - 0.04 13.8 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF2408 PF10303.9 EJS41512.1 - 9.1e-67 223.8 25.1 3.7e-47 160.3 3.9 5.1 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) MtrG PF04210.13 EJS41512.1 - 0.02 14.7 1.1 5 7.1 0.0 3.5 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G MLD PF11647.8 EJS41512.1 - 0.3 11.4 7.7 0.23 11.8 0.4 3.9 5 0 0 5 5 5 0 Membrane Localization Domain Adap_comp_sub PF00928.21 EJS41513.1 - 5.1e-93 311.2 1.0 7.3e-93 310.7 1.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EJS41513.1 - 1.7e-08 34.5 0.3 3.2e-08 33.6 0.3 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Phos_pyr_kin PF08543.12 EJS41514.1 - 1.5e-79 266.9 0.6 1.8e-79 266.6 0.6 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EJS41514.1 - 5e-65 219.2 0.1 6.8e-65 218.8 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 EJS41514.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.4 1 1 0 1 1 1 0 pfkB family carbohydrate kinase HK PF02110.15 EJS41514.1 - 0.034 13.5 0.1 0.09 12.2 0.1 1.7 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 EJS41514.1 - 0.072 12.6 0.1 0.14 11.6 0.1 1.6 1 1 0 1 1 1 0 Carbohydrate kinase Synaptobrevin PF00957.21 EJS41516.1 - 1.4e-31 108.1 1.7 1.6e-31 107.9 1.7 1.0 1 0 0 1 1 1 1 Synaptobrevin Prominin PF05478.11 EJS41516.1 - 0.058 11.4 0.1 0.073 11.0 0.1 1.1 1 0 0 1 1 1 0 Prominin ABC2_membrane PF01061.24 EJS41517.1 - 3e-82 275.1 55.3 1.5e-42 145.4 23.9 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EJS41517.1 - 1.6e-36 125.9 0.0 7.6e-18 65.3 0.0 3.0 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EJS41517.1 - 4.8e-29 100.1 10.7 1.3e-27 95.5 0.0 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EJS41517.1 - 1e-13 51.7 0.0 3.7e-13 49.9 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 EJS41517.1 - 1.3e-06 28.1 0.1 0.00016 21.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJS41517.1 - 6.2e-05 23.5 0.2 0.0014 19.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EJS41517.1 - 8.8e-05 23.1 0.7 0.013 16.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EJS41517.1 - 0.00013 22.1 0.0 0.017 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EJS41517.1 - 0.0002 21.3 0.1 0.026 14.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJS41517.1 - 0.00022 20.9 0.4 0.0082 15.9 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJS41517.1 - 0.00033 20.6 0.0 0.0063 16.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EJS41517.1 - 0.00087 19.6 0.3 0.2 11.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EJS41517.1 - 0.0015 19.1 0.0 0.027 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EJS41517.1 - 0.0066 15.9 0.0 0.95 8.9 0.0 2.7 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 EJS41517.1 - 0.012 15.2 1.5 0.97 9.0 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EJS41517.1 - 0.022 14.7 2.2 3.1 7.7 0.2 3.1 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 EJS41517.1 - 0.022 15.0 2.0 0.29 11.4 0.5 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EJS41517.1 - 0.032 14.0 0.7 2.3 7.9 0.4 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EJS41517.1 - 0.11 11.8 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Glu-tRNAGln PF02686.15 EJS41518.1 - 0.036 14.3 0.1 0.092 13.1 0.1 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit vATP-synt_E PF01991.18 EJS41519.1 - 4.1e-68 228.7 16.8 4.8e-68 228.5 16.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phlebovirus_NSM PF07246.11 EJS41519.1 - 0.13 11.6 10.6 0.024 14.0 7.2 1.4 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M UPF0515 PF15135.6 EJS41519.1 - 1.1 8.6 2.6 1.9 7.8 2.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Folliculin PF11704.8 EJS41519.1 - 4 7.3 6.4 5.2 6.9 5.9 1.7 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4162 PF13732.6 EJS41519.1 - 5.2 7.9 7.9 1.1 10.1 2.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) UPF0449 PF15136.6 EJS41520.1 - 0.21 12.0 1.6 0.63 10.6 0.8 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 tRNA-synt_2c PF01411.19 EJS41521.1 - 3e-230 765.4 0.2 5.1e-230 764.7 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EJS41521.1 - 2.1e-18 66.1 0.1 5e-18 64.9 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EJS41521.1 - 2e-15 57.4 2.6 4.4e-15 56.3 2.6 1.6 1 0 0 1 1 1 1 DHHA1 domain Halogen_Hydrol PF10112.9 EJS41521.1 - 0.00095 19.2 2.2 0.026 14.5 0.5 2.3 2 0 0 2 2 2 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein Z1 PF10593.9 EJS41521.1 - 0.075 12.5 0.3 0.17 11.4 0.3 1.5 1 0 0 1 1 1 0 Z1 domain Glyco_transf_24 PF18404.1 EJS41522.1 - 1.7e-34 119.5 0.3 3.5e-34 118.5 0.3 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EJS41522.1 - 2.4e-18 67.0 3.4 1.9e-17 64.1 2.1 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EJS41522.1 - 3.2e-07 30.3 2.3 3.2e-07 30.3 2.3 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Stealth_CR2 PF11380.8 EJS41522.1 - 0.089 13.0 2.6 0.16 12.2 0.2 2.7 3 0 0 3 3 3 0 Stealth protein CR2, conserved region 2 Fungal_trans PF04082.18 EJS41523.1 - 1.7e-37 128.9 5.7 2.3e-37 128.5 3.7 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS41523.1 - 6.3e-08 32.6 8.5 1.1e-07 31.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGAP PF00616.19 EJS41523.1 - 0.017 14.8 0.5 0.056 13.2 0.0 2.2 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Macoilin PF09726.9 EJS41523.1 - 0.19 10.2 3.9 0.31 9.5 3.9 1.2 1 0 0 1 1 1 0 Macoilin family SWIRM PF04433.17 EJS41524.1 - 4.9e-08 33.2 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain UQ_con PF00179.26 EJS41525.1 - 1.8e-50 170.3 0.1 2e-50 170.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EJS41525.1 - 0.0015 18.3 0.4 0.0029 17.4 0.4 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 EJS41525.1 - 0.0029 17.9 0.1 0.0039 17.5 0.1 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EJS41525.1 - 0.003 17.2 0.0 0.0049 16.6 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RPA43_OB PF17875.1 EJS41526.1 - 2.1e-31 109.1 0.1 2.1e-31 109.1 0.1 1.7 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EJS41526.1 - 1.5e-13 50.9 0.0 3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rpb1_5 PF04998.17 EJS41527.1 - 6.2e-99 330.8 5.8 8.8e-98 327.0 2.6 3.1 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EJS41527.1 - 9.7e-71 237.3 0.3 2.2e-70 236.2 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EJS41527.1 - 6.3e-38 130.2 0.0 5.4e-37 127.1 0.0 2.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EJS41527.1 - 4.1e-26 92.1 0.2 4.1e-26 92.1 0.2 3.5 4 1 0 4 4 4 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EJS41527.1 - 1.2e-23 83.1 2.7 3e-23 81.8 0.0 3.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Cwf_Cwc_15 PF04889.12 EJS41527.1 - 0.0056 16.5 19.3 0.0056 16.5 19.3 2.7 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein HLH PF00010.26 EJS41529.1 - 1.1e-20 73.4 0.7 2.4e-20 72.3 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain IMS PF00817.20 EJS41530.1 - 2.2e-27 95.9 0.0 4.5e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 EJS41530.1 - 2.8e-14 53.3 0.0 9.8e-14 51.5 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EJS41530.1 - 1.2e-10 41.6 0.1 5.3e-10 39.5 0.1 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_C PF11799.8 EJS41530.1 - 2.2e-09 38.0 0.0 7.5e-09 36.3 0.0 2.0 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain LIG3_BRCT PF16759.5 EJS41530.1 - 3.7e-06 27.1 0.0 8.8e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 EJS41530.1 - 1e-05 25.4 0.1 2.2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain REV1_C PF16727.5 EJS41530.1 - 0.00015 22.1 0.0 0.00035 20.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain mCpol PF18182.1 EJS41530.1 - 0.00075 19.8 0.0 0.0032 17.8 0.0 2.1 1 0 0 1 1 1 1 minimal CRISPR polymerase domain PK PF00224.21 EJS41531.1 - 8e-156 518.3 0.3 1e-155 517.9 0.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EJS41531.1 - 1.4e-31 109.2 0.0 3e-31 108.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EJS41531.1 - 0.00032 19.9 0.9 0.00063 18.9 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family AA_permease PF00324.21 EJS41532.1 - 2.1e-151 504.8 39.4 2.4e-151 504.6 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS41532.1 - 9.3e-24 84.0 43.9 1.2e-23 83.7 43.9 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 EJS41534.1 - 6.6e-54 183.0 0.0 1.3e-53 182.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41534.1 - 1.1e-29 103.5 0.0 1.7e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EJS41534.1 - 1.6e-15 57.2 0.0 4.8e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 EJS41534.1 - 3e-07 29.6 0.0 6.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EJS41534.1 - 0.00017 21.0 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJS41534.1 - 0.0042 16.4 0.0 0.0095 15.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJS41534.1 - 0.034 14.1 0.1 0.97 9.3 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Yop-YscD_cpl PF16697.5 EJS41534.1 - 0.072 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain TFB6 PF17110.5 EJS41535.1 - 3.6e-28 98.4 0.0 2.7e-27 95.6 0.0 2.1 1 1 1 2 2 2 1 Subunit 11 of the general transcription factor TFIIH SOG2 PF10428.9 EJS41536.1 - 4.3e-151 504.6 17.6 4.3e-151 504.6 17.6 1.5 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.6 EJS41536.1 - 1.9e-19 69.2 26.3 5.2e-11 42.1 2.9 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EJS41536.1 - 1.6e-12 47.4 18.4 4.9e-07 30.0 0.5 4.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EJS41536.1 - 0.0057 17.0 8.5 51 5.0 0.0 6.0 5 0 0 5 5 5 0 Leucine Rich Repeat SpecificRecomb PF10136.9 EJS41536.1 - 0.014 13.8 0.3 0.028 12.7 0.3 1.4 1 0 0 1 1 1 0 Site-specific recombinase Syntaxin_2 PF14523.6 EJS41536.1 - 0.59 10.5 0.1 0.59 10.5 0.1 4.4 4 1 0 4 4 4 0 Syntaxin-like protein LRR_6 PF13516.6 EJS41536.1 - 1.4 9.1 14.2 2.2 8.5 0.0 5.6 5 0 0 5 5 5 0 Leucine Rich repeat ETF_QO PF05187.13 EJS41538.1 - 5.8e-45 151.7 0.1 1.2e-44 150.7 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EJS41538.1 - 7.6e-10 38.9 0.1 1e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EJS41538.1 - 5.3e-08 32.4 0.1 0.00018 20.8 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 EJS41538.1 - 5e-07 29.1 2.3 0.013 14.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EJS41538.1 - 1.9e-06 28.0 0.2 4.6e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EJS41538.1 - 2e-05 24.1 0.1 2.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJS41538.1 - 0.00053 19.3 0.2 0.003 16.9 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJS41538.1 - 0.0036 17.3 0.2 0.0066 16.5 0.2 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_7 PF12838.7 EJS41538.1 - 0.0078 16.8 0.5 0.021 15.4 0.5 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_binding_3 PF01494.19 EJS41538.1 - 0.008 15.5 0.4 0.014 14.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EJS41538.1 - 0.011 15.0 0.3 0.019 14.2 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJS41538.1 - 0.035 12.8 0.6 0.082 11.6 0.3 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EJS41538.1 - 0.075 13.6 1.9 8.6 7.0 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.7 EJS41538.1 - 0.2 11.9 0.5 0.48 10.6 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain Trp_halogenase PF04820.14 EJS41538.1 - 0.55 9.0 1.6 1.3 7.8 0.4 2.0 2 0 0 2 2 2 0 Tryptophan halogenase PX PF00787.24 EJS41539.1 - 2.3e-24 85.6 0.2 2.8e-24 85.3 0.2 1.1 1 0 0 1 1 1 1 PX domain Histone PF00125.24 EJS41540.1 - 6.2e-29 101.0 0.6 1.2e-27 96.8 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EJS41540.1 - 1.5e-19 70.0 2.1 2.6e-19 69.3 2.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RNA_pol_3_Rpc31 PF11705.8 EJS41540.1 - 0.16 12.2 11.3 0.33 11.2 11.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 EJS41540.1 - 0.36 10.5 9.0 0.71 9.6 9.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-X PF09415.10 EJS41540.1 - 0.74 10.2 6.7 0.23 11.8 0.3 2.4 2 0 0 2 2 2 0 CENP-S associating Centromere protein X DNA_pol_phi PF04931.13 EJS41540.1 - 2.1 6.3 10.3 2.5 6.1 10.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi SAM_2 PF07647.17 EJS41541.1 - 1.5e-08 34.6 0.4 4.3e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EJS41541.1 - 0.0021 18.5 0.1 0.0046 17.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Stork_head PF10264.9 EJS41541.1 - 0.079 13.1 0.1 2.2 8.5 0.1 2.6 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain PDEase_I PF00233.19 EJS41542.1 - 5.5e-50 170.3 5.8 9e-50 169.6 5.8 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EJS41542.1 - 0.0059 16.8 0.4 0.016 15.5 0.1 1.9 2 0 0 2 2 2 1 HD domain Proteasome PF00227.26 EJS41543.1 - 8.9e-53 178.6 0.0 1.2e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJS41543.1 - 4.3e-12 45.5 1.0 6.1e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn_clus PF00172.18 EJS41544.1 - 1.1e-09 38.3 9.4 2.7e-09 37.0 9.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COMM_domain PF07258.14 EJS41544.1 - 0.0059 16.7 0.3 0.018 15.1 0.3 1.9 1 0 0 1 1 1 1 COMM domain TRP PF06011.12 EJS41545.1 - 2.8e-129 431.6 43.2 3.5e-129 431.3 43.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EJS41545.1 - 1.2e-35 122.9 0.3 2.1e-35 122.1 0.3 1.4 1 0 0 1 1 1 1 ML-like domain CH PF00307.31 EJS41546.1 - 2.6e-17 63.0 0.0 3.7e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 EJS41546.1 - 0.0076 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin SLED PF12140.8 EJS41546.1 - 0.11 13.1 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 SLED domain Rad1 PF02144.16 EJS41547.1 - 1.3e-69 234.3 2.9 1.7e-69 234.0 2.9 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ribosomal_L7Ae PF01248.26 EJS41548.1 - 1.6e-22 79.0 0.3 2e-22 78.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GDI PF00996.18 EJS41549.1 - 7.5e-47 159.8 0.2 2e-46 158.4 0.0 1.7 2 1 0 2 2 2 1 GDP dissociation inhibitor DUF1749 PF08538.10 EJS41549.1 - 0.15 11.1 0.3 0.25 10.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Kelch_4 PF13418.6 EJS41550.1 - 1.1e-07 31.7 4.9 0.006 16.6 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EJS41550.1 - 2.7e-06 27.2 0.0 1.2 9.2 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EJS41550.1 - 6.4e-06 26.3 1.1 0.02 15.1 0.0 4.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EJS41550.1 - 0.00011 22.0 3.5 1.5 8.9 1.0 5.0 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 EJS41550.1 - 0.0012 18.4 4.7 0.33 10.6 1.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 EJS41550.1 - 0.0039 17.4 4.0 0.14 12.5 0.0 4.5 4 0 0 4 4 4 1 Kelch motif Aldedh PF00171.22 EJS41552.1 - 2.1e-182 606.7 0.3 2.4e-182 606.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EJS41552.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EJS41552.1 - 0.027 13.9 0.1 7.1 6.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ELFV_dehydrog PF00208.21 EJS41553.1 - 3.2e-84 282.5 2.7 3.9e-84 282.2 2.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EJS41553.1 - 8.3e-47 158.3 0.0 1.7e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AATase PF07247.12 EJS41554.1 - 1.3e-195 650.7 0.0 1.5e-195 650.5 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Linker_histone PF00538.19 EJS41554.1 - 0.042 14.2 1.7 0.59 10.5 0.1 2.8 3 0 0 3 3 3 0 linker histone H1 and H5 family Fungal_trans PF04082.18 EJS41555.1 - 2.8e-12 46.2 0.1 4.2e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS41555.1 - 1.9e-08 34.3 6.8 3.5e-08 33.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Titin_Ig-rpts PF06582.12 EJS41555.1 - 0.22 11.5 2.2 11 6.0 0.1 2.7 2 0 0 2 2 2 0 Titin repeat FAD_binding_8 PF08022.12 EJS41556.1 - 2.9e-29 101.4 0.0 6.5e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EJS41556.1 - 6e-28 97.9 0.0 1e-27 97.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EJS41556.1 - 3.3e-25 88.6 17.4 1e-24 87.0 11.8 3.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FIT1_2 PF17357.2 EJS41557.1 - 2.4e-31 107.7 28.2 2.4e-31 107.7 28.2 2.1 2 1 1 3 3 3 1 Facilitor Of iron transport 1 and 2 SR-25 PF10500.9 EJS41557.1 - 0.38 10.3 13.4 0.49 10.0 13.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.19 EJS41557.1 - 1.5 9.5 5.8 0.67 10.6 2.1 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein PAP1 PF08601.10 EJS41557.1 - 3.1 7.4 15.5 3.4 7.3 15.5 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 EJS41557.1 - 5.4 5.5 6.2 5.8 5.3 6.2 1.1 1 0 0 1 1 1 0 Macoilin family FIT1_2 PF17357.2 EJS41558.1 - 1.2e-05 25.3 73.1 0.00093 19.2 35.4 3.3 1 1 2 3 3 3 2 Facilitor Of iron transport 1 and 2 DUF3952 PF13130.6 EJS41558.1 - 0.062 13.5 1.7 3.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) SPX PF03105.19 EJS41558.1 - 4.8 7.0 8.6 6.3 6.6 8.6 1.2 1 0 0 1 1 1 0 SPX domain FAD_binding_8 PF08022.12 EJS41559.1 - 1.9e-28 98.7 0.1 1.9e-28 98.7 0.1 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 EJS41559.1 - 4.2e-25 88.7 0.0 6.8e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EJS41559.1 - 1.1e-20 74.0 16.5 1.1e-20 74.0 16.5 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component HEPN_DZIP3 PF18738.1 EJS41559.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN FAD_binding_7 PF03441.14 EJS41560.1 - 3.5e-63 212.8 3.2 9.3e-63 211.4 1.2 2.4 2 1 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EJS41560.1 - 5.3e-24 85.1 0.0 1.3e-23 83.9 0.0 1.6 1 1 0 1 1 1 1 DNA photolyase MFS_1 PF07690.16 EJS41561.1 - 1e-26 93.7 56.8 2.2e-26 92.6 50.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EJS41561.1 - 3.7e-13 48.8 24.5 5.3e-11 41.6 24.6 2.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2407_C PF13373.6 EJS41562.1 - 1.6e-45 154.7 1.4 2.6e-45 154.0 1.4 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EJS41562.1 - 7.8e-23 81.0 0.0 3e-22 79.2 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Acetyltransf_11 PF13720.6 EJS41562.1 - 0.081 13.4 0.3 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF5592 PF17332.2 EJS41562.1 - 0.2 12.2 0.5 0.39 11.3 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5592) RNA_pol_Rpb8 PF03870.15 EJS41563.1 - 1.1e-45 155.2 0.0 1.3e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EJS41563.1 - 0.00022 21.3 0.1 0.36 10.9 0.0 2.0 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G NifU_N PF01592.16 EJS41564.1 - 1.3e-55 187.0 0.1 1.5e-55 186.8 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EJS41564.1 - 0.0032 17.7 0.2 0.006 16.8 0.2 1.4 1 0 0 1 1 1 1 TSCPD domain DUF1221 PF06760.11 EJS41565.1 - 0.084 12.4 1.0 0.18 11.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) TRSP PF12500.8 EJS41565.1 - 0.13 12.2 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 FdtA PF05523.11 EJS41565.1 - 0.14 11.9 1.2 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 WxcM-like, C-terminal WD40 PF00400.32 EJS41566.1 - 0.00014 22.6 3.9 0.015 16.1 0.3 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat CENP-B_dimeris PF09026.10 EJS41566.1 - 6.5 7.2 12.6 22 5.5 10.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pkinase PF00069.25 EJS41567.1 - 1.6e-73 247.3 0.0 2.3e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41567.1 - 6e-38 130.6 0.0 1.1e-37 129.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS41567.1 - 1.7e-08 34.2 0.0 3.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EJS41567.1 - 2.2e-05 24.2 0.1 0.22 11.1 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EJS41567.1 - 0.00012 21.0 0.0 0.00043 19.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EJS41567.1 - 0.001 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJS41567.1 - 0.0033 17.4 0.0 0.11 12.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EJS41567.1 - 0.022 13.8 0.0 0.063 12.3 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EJS41567.1 - 0.054 12.4 1.4 0.059 12.3 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase PF00069.25 EJS41568.1 - 2.5e-64 217.2 0.0 3.8e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41568.1 - 6e-40 137.2 0.0 9.8e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS41568.1 - 4.3e-10 39.4 0.0 7.1e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJS41568.1 - 0.00049 20.1 0.1 0.0072 16.3 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EJS41568.1 - 0.00063 19.4 0.1 0.0013 18.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EJS41568.1 - 0.0024 17.2 0.1 0.0053 16.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DHFR_1 PF00186.19 EJS41569.1 - 2e-30 105.6 0.0 3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase Oxysterol_BP PF01237.18 EJS41570.1 - 1.6e-58 198.4 7.1 3.1e-56 190.8 7.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF1539 PF07560.11 EJS41570.1 - 0.048 13.7 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) TruD PF01142.18 EJS41573.1 - 3.5e-76 256.7 0.7 4.1e-70 236.7 0.1 3.3 1 1 1 2 2 2 2 tRNA pseudouridine synthase D (TruD) Cucumopine_C PF18631.1 EJS41573.1 - 0.13 12.2 0.1 6.5 6.7 0.0 2.7 3 0 0 3 3 3 0 Cucumopine synthase C-terminal helical bundle domain MOZ_SAS PF01853.18 EJS41574.1 - 8.3e-83 276.4 0.4 1.3e-82 275.8 0.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EJS41574.1 - 2.6e-21 75.0 0.5 6.7e-21 73.6 0.5 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EJS41574.1 - 9e-21 73.5 0.5 1.9e-20 72.5 0.5 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EJS41574.1 - 0.002 18.5 0.0 0.0049 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJS41574.1 - 0.0035 17.6 0.0 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family HTH_Mga PF08280.11 EJS41574.1 - 0.034 14.2 1.4 0.089 12.8 1.4 1.7 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DAGAT PF03982.13 EJS41575.1 - 4.1e-81 272.1 2.1 1.9e-72 243.7 0.0 2.1 1 1 1 2 2 2 2 Diacylglycerol acyltransferase adh_short PF00106.25 EJS41576.1 - 4.4e-22 78.5 0.0 5.6e-17 61.8 0.0 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EJS41576.1 - 2.2e-14 53.6 0.0 3.2e-09 36.7 0.0 3.0 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EJS41576.1 - 0.0037 16.7 0.0 0.009 15.4 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EJS41576.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.4 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 EJS41576.1 - 0.044 13.2 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CLP1_P PF16575.5 EJS41577.1 - 1.1e-31 110.1 0.0 1.5e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EJS41577.1 - 1.2e-25 90.2 0.0 2e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 EJS41577.1 - 5.8e-21 74.5 0.0 1.3e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_7 PF12775.7 EJS41577.1 - 0.00091 18.8 0.1 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region PduV-EutP PF10662.9 EJS41577.1 - 0.0028 17.4 0.0 0.007 16.1 0.0 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EJS41577.1 - 0.0043 17.5 0.0 0.0059 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 EJS41577.1 - 0.0074 16.5 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EJS41577.1 - 0.048 13.4 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EJS41577.1 - 0.1 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EJS41577.1 - 0.1 12.7 0.0 0.37 10.9 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EJS41577.1 - 0.17 12.4 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.23 EJS41577.1 - 0.18 11.8 0.0 0.34 11.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rhodanese PF00581.20 EJS41578.1 - 1.9e-17 63.7 0.0 2.3e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Tma16 PF11176.8 EJS41579.1 - 2.3e-38 131.4 2.3 2.5e-38 131.2 2.3 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Acetyltransf_10 PF13673.7 EJS41580.1 - 2e-08 34.3 0.0 2.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJS41580.1 - 3.4e-06 27.3 0.0 4.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJS41580.1 - 3.7e-06 27.3 0.0 4.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJS41580.1 - 0.072 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DnaJ PF00226.31 EJS41581.1 - 2.3e-17 62.9 0.3 1.7e-16 60.1 0.1 2.7 2 0 0 2 2 2 1 DnaJ domain Sec63 PF02889.16 EJS41581.1 - 0.017 14.3 0.0 0.19 10.9 0.0 2.4 1 1 1 2 2 2 0 Sec63 Brl domain DUF2232 PF09991.9 EJS41581.1 - 0.16 11.1 0.0 0.38 9.9 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) TFR_dimer PF04253.15 EJS41582.1 - 1.9e-32 111.9 0.0 4.1e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EJS41582.1 - 0.00027 20.7 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EJS41582.1 - 0.068 13.2 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 PA domain EF-hand_7 PF13499.6 EJS41583.1 - 6.8e-27 93.7 9.5 9.8e-16 58.0 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EJS41583.1 - 1.3e-23 80.7 14.7 3.4e-08 32.5 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EJS41583.1 - 5.2e-19 66.5 12.1 5.1e-07 29.1 0.2 4.2 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EJS41583.1 - 1.8e-16 59.7 10.9 1.1e-10 41.2 0.4 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EJS41583.1 - 1.4e-13 49.6 6.9 5.2e-05 22.5 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EJS41583.1 - 2.4e-09 37.4 0.5 0.00058 20.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EJS41583.1 - 1.3e-06 28.3 1.3 0.0073 16.2 0.1 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EJS41583.1 - 0.0006 20.1 0.9 0.25 11.7 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EJS41583.1 - 0.013 15.7 0.1 3.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I domain PhetRS_B1 PF18262.1 EJS41583.1 - 0.015 15.5 1.0 0.07 13.4 0.3 2.2 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain EF-hand_14 PF17959.1 EJS41583.1 - 0.056 13.8 0.4 0.36 11.2 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 EJS41583.1 - 0.062 13.2 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 SurA N-terminal domain MgtE_N PF03448.17 EJS41583.1 - 0.098 13.3 3.1 0.11 13.1 0.2 2.3 3 0 0 3 3 3 0 MgtE intracellular N domain DUF1296 PF06972.11 EJS41583.1 - 0.14 12.3 0.6 12 6.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) HTH_40 PF14493.6 EJS41583.1 - 0.17 12.3 0.5 1.3 9.5 0.5 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain Caleosin PF05042.13 EJS41583.1 - 0.18 11.7 1.3 3.9 7.4 0.0 3.0 1 1 3 4 4 4 0 Caleosin related protein EF-hand_11 PF08976.11 EJS41583.1 - 0.18 12.7 0.2 0.75 10.7 0.1 1.9 1 1 1 2 2 2 0 EF-hand domain Staphylokinase PF02821.16 EJS41583.1 - 0.28 11.6 1.7 4.9 7.6 1.4 2.6 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family HIT PF01230.23 EJS41584.1 - 2.8e-21 76.1 0.2 5.1e-21 75.2 0.2 1.4 1 0 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 EJS41584.1 - 1.5e-17 63.8 4.9 1.5e-17 63.8 4.9 2.0 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EJS41584.1 - 1.2e-13 51.5 2.5 6.1e-12 46.0 2.5 2.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.29 EJS41585.1 - 3.6e-42 143.9 0.0 6.7e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS41585.1 - 1.6e-08 34.2 0.1 3.5e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EJS41585.1 - 5.1e-08 32.7 0.3 1.2e-07 31.5 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EJS41585.1 - 4.5e-07 30.4 1.8 9e-05 22.9 0.0 3.1 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EJS41585.1 - 1.2e-06 28.5 0.2 4.2e-05 23.6 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EJS41585.1 - 3.5e-05 24.0 0.0 8.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EJS41585.1 - 6.5e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EJS41585.1 - 0.00019 21.4 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EJS41585.1 - 0.0017 18.6 0.2 0.031 14.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 EJS41585.1 - 0.0023 18.3 0.0 0.005 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EJS41585.1 - 0.0027 17.0 0.1 0.005 16.1 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EJS41585.1 - 0.0062 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EJS41585.1 - 0.008 16.4 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJS41585.1 - 0.008 16.7 0.4 0.033 14.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain Fib_alpha PF08702.10 EJS41585.1 - 0.0096 16.1 3.6 0.022 14.9 3.6 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family AAA_24 PF13479.6 EJS41585.1 - 0.013 15.3 0.1 0.038 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EJS41585.1 - 0.013 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Prot_ATP_OB_N PF17758.1 EJS41585.1 - 0.02 14.5 0.1 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 EJS41585.1 - 0.027 14.7 0.7 0.067 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EJS41585.1 - 0.041 13.7 4.5 0.96 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJS41585.1 - 0.047 13.2 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EJS41585.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EJS41585.1 - 0.053 12.9 1.4 0.11 11.8 0.0 2.2 3 0 0 3 3 3 0 KaiC PhoH PF02562.16 EJS41585.1 - 0.061 12.8 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EJS41585.1 - 0.068 12.7 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EJS41585.1 - 0.078 12.1 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 EJS41585.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EJS41585.1 - 0.16 11.9 0.1 0.51 10.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EJS41585.1 - 1.1 9.7 3.3 2.9 8.4 0.1 2.8 2 1 1 3 3 3 0 ABC transporter NTP_transf_3 PF12804.7 EJS41586.1 - 2.4e-05 24.7 0.0 3.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EJS41586.1 - 0.00055 19.0 0.9 0.0019 17.2 1.0 1.8 1 1 0 1 1 1 1 L-fucokinase Hexapep PF00132.24 EJS41586.1 - 0.004 16.8 3.3 0.18 11.6 0.2 3.3 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EJS41586.1 - 0.011 15.4 0.8 0.075 12.8 0.2 2.6 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 EJS41586.1 - 0.017 15.1 0.0 0.067 13.1 0.0 1.9 2 0 0 2 2 2 0 Cytidylyltransferase DUF4954 PF16314.5 EJS41586.1 - 0.13 10.4 1.4 0.61 8.1 1.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) DUF2547 PF10818.8 EJS41586.1 - 0.41 11.6 3.6 4 8.4 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) ATP_bind_1 PF03029.17 EJS41587.1 - 2.2e-82 276.5 0.1 2.8e-82 276.1 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EJS41587.1 - 0.0047 17.5 1.0 0.35 11.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 EJS41587.1 - 0.046 12.7 0.1 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HUN PF08729.10 EJS41587.1 - 0.048 13.7 0.5 0.13 12.2 0.5 1.8 1 0 0 1 1 1 0 HPC2 and ubinuclein domain AAA_22 PF13401.6 EJS41587.1 - 0.058 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EJS41587.1 - 0.063 13.7 2.6 0.3 11.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EJS41587.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EJS41587.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TBCA PF02970.16 EJS41589.1 - 3.7e-26 91.3 7.8 4.7e-26 90.9 7.8 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A FapA PF03961.13 EJS41589.1 - 0.29 9.7 4.2 0.33 9.5 4.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pkinase PF00069.25 EJS41590.1 - 2.5e-48 164.8 0.4 5.6e-44 150.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41590.1 - 3.7e-19 69.0 0.0 1.1e-18 67.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.32 EJS41591.1 - 4.8e-23 81.0 21.5 1.3e-05 25.8 0.2 7.6 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS41591.1 - 2.3e-05 24.6 0.6 0.24 11.7 0.3 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJS41591.1 - 0.00058 18.6 3.9 0.4 9.3 0.2 3.4 3 1 0 3 3 3 2 Nucleoporin Nup120/160 DivIC PF04977.15 EJS41591.1 - 0.094 12.5 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator MbeD_MobD PF04899.12 EJS41591.1 - 0.098 12.8 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 MbeD/MobD like V_ATPase_I PF01496.19 EJS41592.1 - 0 1029.6 1.5 0 1029.4 1.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PI_PP_I PF18363.1 EJS41592.1 - 0.02 15.0 0.8 0.058 13.6 0.2 2.1 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF2096 PF09869.9 EJS41592.1 - 0.092 12.8 0.4 0.18 11.9 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Mtc PF03820.17 EJS41593.1 - 4.2e-127 423.5 0.0 4.7e-127 423.3 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.32 EJS41594.1 - 1.7e-27 95.1 16.4 1.6e-07 31.8 0.1 6.8 8 0 0 8 8 8 5 WD domain, G-beta repeat NLE PF08154.12 EJS41594.1 - 1.5e-23 83.1 0.0 2.8e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EJS41594.1 - 4e-08 32.4 7.0 0.00041 19.1 0.4 3.6 1 1 2 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EJS41594.1 - 0.00045 20.5 0.2 0.016 15.5 0.0 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EJS41594.1 - 0.075 12.3 3.1 1.2 8.4 0.7 2.8 2 1 0 2 2 2 0 WD40-like domain MFS_1 PF07690.16 EJS41595.1 - 2.6e-25 89.1 33.9 2.6e-25 89.1 33.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EJS41595.1 - 0.0017 17.3 0.7 0.0017 17.3 0.7 3.5 3 1 0 3 3 3 2 Sugar (and other) transporter IPPT PF01715.17 EJS41596.1 - 1.2e-67 228.1 0.3 2e-67 227.4 0.3 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EJS41596.1 - 2.2e-05 24.0 0.1 0.00019 20.9 0.0 2.4 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 EJS41596.1 - 0.00029 21.0 0.0 0.0011 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EJS41596.1 - 0.00065 20.2 0.0 0.017 15.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EJS41596.1 - 0.014 15.8 0.0 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 EJS41596.1 - 0.03 14.2 0.2 0.069 13.0 0.2 1.6 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 EJS41596.1 - 0.056 12.7 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Hpr_kinase_C PF07475.12 EJS41596.1 - 0.079 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain CbiA PF01656.23 EJS41596.1 - 0.088 12.9 0.2 0.33 11.0 0.2 2.0 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cytidylate_kin PF02224.18 EJS41596.1 - 0.093 12.4 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_22 PF13401.6 EJS41596.1 - 0.12 12.6 0.0 1 9.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain ParA PF10609.9 EJS41596.1 - 0.13 11.7 0.2 0.21 11.0 0.2 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase IstB_IS21 PF01695.17 EJS41596.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein dNK PF01712.19 EJS41596.1 - 0.2 11.5 4.5 1.1 9.1 0.0 3.1 3 0 0 3 3 3 0 Deoxynucleoside kinase BRO1 PF03097.18 EJS41597.1 - 1.4e-102 343.4 8.2 1.4e-102 343.4 8.2 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EJS41597.1 - 1.1e-29 103.7 23.2 1.8e-28 99.7 18.8 2.7 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV ArnB_C PF18677.1 EJS41597.1 - 0.0098 16.0 0.7 0.0098 16.0 0.7 3.2 3 1 0 3 3 3 1 Archaellum regulatory network B, C-terminal domain DUF5113 PF17140.4 EJS41597.1 - 0.96 9.2 5.7 3.4 7.5 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5113) CAF20 PF17052.5 EJS41598.1 - 2.8e-54 183.6 0.7 3.1e-54 183.4 0.7 1.0 1 0 0 1 1 1 1 Cap associated factor HEM4 PF02602.15 EJS41599.1 - 1e-48 165.7 0.0 1.2e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD FSH1 PF03959.13 EJS41600.1 - 2.1e-68 230.2 0.0 2.5e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 EJS41600.1 - 0.0043 16.7 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EJS41600.1 - 0.024 13.9 0.0 0.088 12.1 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EJS41600.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Phosducin PF02114.16 EJS41601.1 - 1e-06 27.9 5.5 3.3e-05 23.0 5.5 2.1 1 1 0 1 1 1 1 Phosducin RUN PF02759.19 EJS41601.1 - 0.013 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 RUN domain His_Phos_1 PF00300.22 EJS41602.1 - 9.9e-43 146.1 0.1 1.1e-42 145.9 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rhodanese PF00581.20 EJS41603.1 - 5.9e-17 62.1 0.0 7.7e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 EJS41604.1 - 1.7e-10 41.4 0.0 2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain RRP36 PF06102.12 EJS41605.1 - 2.7e-39 134.8 28.7 2.7e-39 134.8 28.7 2.0 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 Bacillus_HBL PF05791.11 EJS41605.1 - 0.45 10.3 10.5 0.084 12.7 5.8 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SNF2_N PF00176.23 EJS41606.1 - 1.2e-71 241.3 0.5 4.3e-71 239.4 0.5 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJS41606.1 - 4.2e-22 78.6 0.7 2e-19 69.9 0.0 3.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.6 EJS41606.1 - 5.7e-17 62.1 2.8 5.7e-17 62.1 2.8 3.6 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex Bromodomain PF00439.25 EJS41606.1 - 5.9e-15 55.1 0.1 2.6e-14 53.0 0.1 2.2 1 0 0 1 1 1 1 Bromodomain QLQ PF08880.11 EJS41606.1 - 2e-09 37.0 0.5 2e-09 37.0 0.5 3.4 3 0 0 3 3 3 1 QLQ ResIII PF04851.15 EJS41606.1 - 3.2e-08 33.8 0.0 3.2e-08 33.8 0.0 3.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.13 EJS41606.1 - 0.0025 18.1 12.6 0.0025 18.1 12.6 4.2 5 0 0 5 5 5 1 HSA P5-ATPase PF12409.8 EJS41607.1 - 6e-36 123.3 0.2 2.2e-35 121.5 0.0 2.1 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 EJS41607.1 - 2.6e-30 105.3 0.3 7.2e-30 103.9 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EJS41607.1 - 1.6e-14 54.7 0.1 2.4e-07 31.3 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJS41607.1 - 1.9e-06 27.9 0.0 4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EJS41607.1 - 0.0036 17.1 0.1 1.7 8.3 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EJS41607.1 - 0.096 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus CBP_BcsF PF11120.8 EJS41607.1 - 0.21 11.7 1.1 0.82 9.8 1.1 2.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF Mpv17_PMP22 PF04117.12 EJS41608.1 - 2.6e-18 66.0 0.2 2.6e-18 66.0 0.2 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family SLATT_5 PF18160.1 EJS41608.1 - 2.4 7.4 7.8 0.54 9.6 3.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 RRS1 PF04939.12 EJS41609.1 - 1.5e-59 200.5 5.8 1.7e-59 200.3 5.8 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Membr_traf_MHD PF10540.9 EJS41610.1 - 8.2e-42 142.9 1.1 1.2e-40 139.1 0.3 2.8 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EJS41610.1 - 8.3e-11 42.1 0.0 2.9e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 EJS41610.1 - 4.7e-05 22.1 0.1 0.00022 20.0 0.0 2.0 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) CybS PF05328.12 EJS41611.1 - 1.4e-46 157.5 0.0 2.1e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit COX7a PF02238.15 EJS41611.1 - 0.61 10.5 2.5 8.7 6.8 0.1 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII MBF1 PF08523.10 EJS41612.1 - 1e-24 86.8 1.6 1e-24 86.8 1.6 2.0 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EJS41612.1 - 9.4e-13 48.0 0.1 1.4e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EJS41612.1 - 3.5e-05 24.1 0.0 6.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EJS41612.1 - 0.037 14.1 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TRAP-gamma PF07074.12 EJS41612.1 - 0.11 12.1 1.2 0.15 11.7 1.1 1.3 1 1 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) ChAPs PF09295.10 EJS41613.1 - 1.3e-172 574.3 1.3 1.8e-172 573.8 1.3 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 EJS41613.1 - 0.0012 19.0 4.0 0.013 15.7 1.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EJS41613.1 - 0.0031 17.5 0.2 0.82 9.9 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJS41613.1 - 0.035 14.6 0.1 0.58 10.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_A3L PF05288.11 EJS41613.1 - 0.055 13.5 0.6 1.1 9.2 0.5 2.5 2 0 0 2 2 2 0 Poxvirus A3L Protein TPR_8 PF13181.6 EJS41613.1 - 0.089 13.1 0.2 1.1 9.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Leader_CPA1 PF08252.11 EJS41614.1 - 2.3e-16 58.8 7.8 2.4e-16 58.8 7.8 1.0 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide SNF2_N PF00176.23 EJS41615.1 - 1.8e-75 253.8 0.6 4e-75 252.7 0.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EJS41615.1 - 1.5e-38 131.3 3.4 1.5e-38 131.3 3.4 3.9 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 EJS41615.1 - 1.1e-34 119.5 9.4 1.1e-34 119.5 9.4 3.2 2 0 0 2 2 2 1 HAND Helicase_C PF00271.31 EJS41615.1 - 2.8e-21 75.9 0.0 3.5e-19 69.2 0.0 3.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS41615.1 - 4.7e-12 46.2 0.0 4.7e-12 46.2 0.0 4.0 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EJS41615.1 - 7.2e-05 22.6 0.0 0.00023 21.0 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EJS41615.1 - 0.00081 18.7 0.2 0.0024 17.1 0.2 1.8 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_14 PF13173.6 EJS41615.1 - 0.041 13.9 0.5 0.39 10.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain YhzD PF14120.6 EJS41615.1 - 0.13 12.3 2.8 3.7 7.7 0.6 3.5 3 0 0 3 3 3 0 YhzD-like protein DUF2524 PF10732.9 EJS41616.1 - 0.013 15.7 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Med9 PF07544.13 EJS41616.1 - 0.018 15.1 0.4 0.024 14.7 0.4 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 IF2_N PF04760.15 EJS41616.1 - 0.024 14.5 0.2 0.077 12.8 0.1 1.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Baculo_PEP_C PF04513.12 EJS41616.1 - 0.033 14.2 0.4 0.034 14.2 0.4 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PhoU PF01895.19 EJS41616.1 - 0.069 13.6 0.5 0.084 13.4 0.5 1.3 1 0 0 1 1 1 0 PhoU domain TPT PF03151.16 EJS41617.1 - 1e-28 100.6 28.8 1.1e-26 93.9 28.8 3.1 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EJS41617.1 - 5.7e-05 23.3 34.8 0.003 17.7 9.0 4.0 4 0 0 4 4 4 3 EamA-like transporter family Tetraspanin PF00335.20 EJS41617.1 - 0.0085 15.8 0.7 0.0085 15.8 0.7 2.3 3 1 0 3 3 3 1 Tetraspanin family SART-1 PF03343.13 EJS41618.1 - 1.9e-52 178.7 49.7 1.4e-45 156.0 44.1 3.5 2 1 0 2 2 2 2 SART-1 family DUF2986 PF11661.8 EJS41619.1 - 0.26 11.9 1.1 0.56 10.8 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) Cation_efflux PF01545.21 EJS41621.1 - 2.5e-51 174.3 3.8 3.3e-51 173.9 3.8 1.2 1 0 0 1 1 1 1 Cation efflux family RRM_1 PF00076.22 EJS41622.1 - 1.1e-27 95.6 2.9 1.9e-14 53.2 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJS41622.1 - 0.0001 21.9 2.3 0.0059 16.2 0.1 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EJS41622.1 - 0.00051 20.1 0.1 0.11 12.5 0.1 2.5 2 1 0 2 2 2 2 Limkain b1 RRM_7 PF16367.5 EJS41622.1 - 0.0013 18.8 0.4 0.67 10.1 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EJS41622.1 - 0.014 15.2 0.1 0.94 9.4 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 EJS41622.1 - 0.065 13.5 0.2 1.1 9.5 0.0 2.5 1 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Mannosyl_trans3 PF11051.8 EJS41623.1 - 0.0019 17.6 1.8 0.0047 16.3 1.8 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 EJS41623.1 - 0.022 14.3 5.0 0.024 14.2 1.0 2.8 3 1 0 3 3 3 0 Glycosyl transferase family 8 PMT PF02366.18 EJS41624.1 - 1.9e-97 325.7 19.1 3.4e-97 324.8 19.1 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EJS41624.1 - 7.3e-55 185.7 11.0 7.3e-55 185.7 11.0 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EJS41624.1 - 1.5e-22 80.3 0.0 2.6e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 MIR domain LDB19 PF13002.7 EJS41625.1 - 2.2e-99 330.9 1.4 3.3e-99 330.3 1.4 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 EJS41625.1 - 7.7e-06 26.0 0.1 2.2e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain UBM PF14377.6 EJS41625.1 - 0.81 9.2 6.0 1.6 8.3 6.0 1.5 1 0 0 1 1 1 0 Ubiquitin binding region Aldedh PF00171.22 EJS41626.1 - 2e-14 53.0 0.4 1e-08 34.2 0.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 EJS41626.1 - 0.0019 17.4 0.0 0.011 14.8 0.0 2.0 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) Hph PF13694.6 EJS41627.1 - 2.9e-48 164.6 12.8 2.9e-48 164.6 12.8 2.9 2 0 0 2 2 2 1 Sec63/Sec62 complex-interacting family FliJ PF02050.16 EJS41627.1 - 0.0045 17.2 1.5 0.015 15.5 0.7 2.3 1 1 1 2 2 2 1 Flagellar FliJ protein Med15_fungi PF05397.12 EJS41627.1 - 0.0092 16.2 0.2 0.023 15.0 0.2 1.6 1 0 0 1 1 1 1 Mediator complex subunit 15 Myosin_head PF00063.21 EJS41628.1 - 8.9e-285 946.2 14.9 8.9e-285 946.2 14.9 1.8 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.19 EJS41628.1 - 4e-27 94.5 0.9 4e-27 94.5 0.9 3.7 4 0 0 4 4 4 1 DIL domain Myosin_N PF02736.19 EJS41628.1 - 0.00025 20.8 1.1 0.00071 19.4 0.5 2.1 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain NB-ARC PF00931.22 EJS41628.1 - 0.00028 20.1 0.1 0.00028 20.1 0.1 2.6 3 0 0 3 3 3 1 NB-ARC domain AAA_22 PF13401.6 EJS41628.1 - 0.0025 18.1 0.0 0.0025 18.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain RNase_P_Rpp14 PF01900.19 EJS41628.1 - 0.0045 17.2 0.9 0.015 15.5 0.9 2.0 1 0 0 1 1 1 1 Rpp14/Pop5 family AAA_16 PF13191.6 EJS41628.1 - 0.052 13.9 0.2 0.33 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Fungal_trans_2 PF11951.8 EJS41628.1 - 0.12 11.2 2.4 0.26 10.0 0.5 2.4 1 1 1 2 2 2 0 Fungal specific transcription factor domain Sulphotransf PF09037.10 EJS41628.1 - 0.13 11.8 2.1 0.33 10.4 2.1 1.7 1 0 0 1 1 1 0 Stf0 sulphotransferase ABC_tran PF00005.27 EJS41628.1 - 0.33 11.5 0.0 0.33 11.5 0.0 3.1 2 1 0 2 2 2 0 ABC transporter IQ PF00612.27 EJS41628.1 - 0.54 10.2 15.0 3.2 7.8 0.1 5.5 5 0 0 5 5 5 0 IQ calmodulin-binding motif DUF2937 PF11157.8 EJS41628.1 - 2 8.1 5.3 1.6 8.5 1.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) HSF_DNA-bind PF00447.17 EJS41628.1 - 2.2 8.9 6.1 0.44 11.2 0.3 3.0 3 0 0 3 3 2 0 HSF-type DNA-binding Saccharop_dh_N PF04455.12 EJS41628.1 - 3.7 8.0 6.1 1.5 9.3 0.0 3.3 3 0 0 3 3 3 0 LOR/SDH bifunctional enzyme conserved region CbiA PF01656.23 EJS41628.1 - 8.9 6.4 6.9 2.1 8.4 0.0 3.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TetR_C_4 PF08359.11 EJS41629.1 - 0.19 11.9 9.9 0.11 12.7 0.8 3.3 3 0 0 3 3 3 0 YsiA-like protein, C-terminal region Golgin_A5 PF09787.9 EJS41629.1 - 4.7 6.6 34.6 0.84 9.0 21.5 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 ECH_1 PF00378.20 EJS41630.1 - 2.3e-15 56.6 0.0 1.1e-14 54.4 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EJS41630.1 - 2.3e-09 37.2 0.0 3.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SPA PF08616.10 EJS41630.1 - 0.013 15.5 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis Init_tRNA_PT PF04179.12 EJS41630.1 - 0.095 13.0 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain WH1 PF00568.23 EJS41631.1 - 7.5e-37 125.7 0.0 1e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EJS41631.1 - 1.9e-06 27.5 1.5 4.3e-06 26.4 1.5 1.6 1 0 0 1 1 1 1 WH2 motif Aminotran_5 PF00266.19 EJS41632.1 - 2.5e-35 122.2 0.0 3.1e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Ras PF00071.22 EJS41633.1 - 1.6e-51 174.2 0.0 1.9e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS41633.1 - 1.4e-31 109.2 0.1 3.6e-31 107.9 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS41633.1 - 4.9e-12 45.6 0.0 6.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 EJS41633.1 - 0.00029 21.2 0.2 0.0023 18.3 0.2 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 EJS41633.1 - 0.00046 20.3 0.0 0.0009 19.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EJS41633.1 - 0.0013 18.2 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EJS41633.1 - 0.0024 17.4 0.5 0.011 15.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EJS41633.1 - 0.0087 15.3 2.0 1.2 8.2 0.1 2.9 2 1 1 3 3 3 1 G-protein alpha subunit Pox_A32 PF04665.12 EJS41633.1 - 0.0088 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein SRPRB PF09439.10 EJS41633.1 - 0.01 15.2 0.0 0.018 14.5 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EJS41633.1 - 0.02 14.8 0.1 6.8 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 EJS41633.1 - 0.025 13.9 0.2 0.041 13.2 0.2 1.2 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 EJS41633.1 - 0.028 14.0 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ArgoMid PF16487.5 EJS41633.1 - 0.032 14.5 0.1 0.07 13.4 0.1 1.6 1 0 0 1 1 1 0 Mid domain of argonaute AAA_24 PF13479.6 EJS41633.1 - 0.065 12.9 0.3 0.13 12.0 0.3 1.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EJS41633.1 - 0.068 13.2 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EJS41633.1 - 0.092 12.9 0.2 0.23 11.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EJS41633.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 EJS41634.1 - 9.4e-59 198.2 0.2 1.2e-58 197.8 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EJS41634.1 - 8.6e-28 96.9 0.0 1.9e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EJS41634.1 - 1.1e-19 70.5 1.8 2.8e-19 69.3 1.8 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EJS41634.1 - 5.5e-05 23.2 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJS41634.1 - 0.012 15.5 0.2 0.045 13.6 0.1 1.9 1 1 1 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 EJS41634.1 - 0.036 13.8 0.3 11 5.8 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EJS41634.1 - 0.068 12.8 1.4 0.071 12.7 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cellulase PF00150.18 EJS41635.1 - 4.6e-12 46.0 5.6 9.8e-12 44.9 0.0 2.6 2 1 1 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Talin_middle PF09141.10 EJS41635.1 - 0.2 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Talin, middle domain SNF2_N PF00176.23 EJS41636.1 - 4.5e-55 186.8 0.1 4.5e-55 186.8 0.1 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJS41636.1 - 1.6e-16 60.6 2.5 6.5e-16 58.7 0.1 3.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EJS41636.1 - 2.8e-05 24.0 2.3 6.5e-05 22.8 2.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EJS41636.1 - 0.00063 19.7 0.5 0.0015 18.5 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 EJS41636.1 - 0.0025 17.8 0.1 0.0025 17.8 0.1 4.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 EJS41636.1 - 0.0047 16.7 1.3 0.011 15.6 1.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJS41636.1 - 0.0088 15.9 1.1 0.022 14.6 1.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJS41636.1 - 0.01 15.7 2.1 0.024 14.5 2.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EJS41636.1 - 0.014 15.7 3.4 0.032 14.5 3.4 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EJS41636.1 - 0.063 13.1 1.7 0.14 12.0 1.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 EJS41637.1 - 7.6e-46 157.9 24.1 3.8e-25 89.8 16.6 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EJS41637.1 - 2 7.1 5.1 2.6 6.7 5.1 1.1 1 0 0 1 1 1 0 Presenilin Fungal_TACC PF12709.7 EJS41638.1 - 1.1e-31 109.1 16.7 1.1e-31 109.1 16.7 9.5 3 2 5 9 9 9 1 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 EJS41638.1 - 0.14 11.0 114.6 0.017 14.1 14.7 6.2 2 1 4 6 6 6 0 Spc7 kinetochore protein LIAS_N PF16881.5 EJS41639.1 - 4.7e-23 81.7 0.3 1.4e-22 80.2 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EJS41639.1 - 3.7e-14 53.4 0.1 6.2e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.11 EJS41639.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Phyto-Amp PF15438.6 EJS41639.1 - 0.14 12.0 0.5 0.73 9.6 0.2 2.1 2 0 0 2 2 2 0 Antigenic membrane protein of phytoplasma Baculo_PEP_C PF04513.12 EJS41640.1 - 1.6 8.7 29.8 5.8 6.9 4.1 5.1 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLP_protease PF00574.23 EJS41640.1 - 6.4 6.6 10.9 1 9.2 1.6 2.9 2 0 0 2 2 2 0 Clp protease SpoU_methylase PF00588.19 EJS41641.1 - 6.8e-25 87.9 0.0 2.2e-24 86.3 0.0 1.8 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EJS41641.1 - 9.4e-13 48.2 0.0 2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding IGPD PF00475.18 EJS41642.1 - 2.2e-61 206.4 0.6 3.5e-61 205.7 0.6 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DEAD PF00270.29 EJS41643.1 - 1.7e-50 171.2 0.0 4e-50 170.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS41643.1 - 4.1e-33 114.0 0.0 3.9e-32 110.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS41643.1 - 0.0087 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EJS41643.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EJS41643.1 - 0.072 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MMR_HSR1 PF01926.23 EJS41644.1 - 2.9e-09 37.0 0.0 2.6e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJS41644.1 - 3.3e-06 27.1 0.0 8.7e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EJS41644.1 - 0.0011 18.5 0.1 0.0061 16.1 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RNA_helicase PF00910.22 EJS41644.1 - 0.03 14.7 0.3 0.51 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 EJS41644.1 - 0.075 13.6 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 EJS41644.1 - 0.094 12.2 0.2 5.2 6.6 0.1 2.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PHD_2 PF13831.6 EJS41644.1 - 0.095 12.3 0.6 0.96 9.1 0.0 2.4 2 0 0 2 2 2 0 PHD-finger Noc2 PF03715.13 EJS41645.1 - 2.6e-127 424.2 3.7 2.6e-127 424.2 3.7 1.8 2 0 0 2 2 2 1 Noc2p family DUF4048 PF13257.6 EJS41645.1 - 1.9 8.3 14.0 4.3 7.1 14.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) RNA_pol_Rpb2_6 PF00562.28 EJS41646.1 - 3.9e-125 418.0 0.5 7e-125 417.1 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EJS41646.1 - 5e-63 212.3 1.1 8.3e-63 211.6 1.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EJS41646.1 - 4.4e-42 143.9 4.3 6.9e-42 143.2 2.7 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EJS41646.1 - 6.1e-34 116.3 0.2 1.8e-33 114.8 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EJS41646.1 - 3.2e-25 88.2 0.3 1.4e-24 86.1 0.3 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EJS41646.1 - 1.8e-18 66.5 0.0 4.4e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EJS41646.1 - 4.1e-10 40.1 1.4 2e-09 37.8 1.4 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NAPRTase PF04095.16 EJS41647.1 - 1.6e-78 263.6 0.0 2.2e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EJS41647.1 - 4.1e-36 124.1 0.5 7e-36 123.4 0.5 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain RNA_pol_N PF01194.17 EJS41648.1 - 8.5e-30 102.8 0.3 9.7e-30 102.7 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EJS41648.1 - 0.036 14.3 0.2 0.048 13.9 0.2 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Dynamin_N PF00350.23 EJS41649.1 - 3.4e-43 147.6 0.2 3.4e-43 147.6 0.2 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EJS41649.1 - 9.3e-06 25.7 0.1 6.2e-05 23.1 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF1140 PF06600.11 EJS41649.1 - 0.012 16.0 2.9 3.6 8.1 0.0 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1140) CENP-B_dimeris PF09026.10 EJS41649.1 - 0.02 15.2 5.7 0.054 13.9 5.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AAA_16 PF13191.6 EJS41649.1 - 0.041 14.2 0.2 0.15 12.4 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_M PF01031.20 EJS41649.1 - 0.049 12.8 7.7 0.22 10.7 0.0 3.6 3 0 0 3 3 3 0 Dynamin central region AKAP7_RIRII_bdg PF10470.9 EJS41649.1 - 0.069 13.2 0.1 0.48 10.5 0.0 2.4 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Roc PF08477.13 EJS41649.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase EntA_Immun PF08951.10 EJS41649.1 - 0.16 12.3 3.7 0.3 11.5 1.7 2.5 2 0 0 2 2 2 0 Enterocin A Immunity DUF3245 PF11595.8 EJS41649.1 - 2.2 8.7 7.4 4.6 7.7 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Cwf_Cwc_15 PF04889.12 EJS41649.1 - 4.2 7.0 12.6 8.2 6.1 12.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EJS41649.1 - 8 5.7 15.4 15 4.7 15.4 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 EJS41649.1 - 8.9 5.3 14.0 14 4.6 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YqeY PF09424.10 EJS41651.1 - 3.8e-20 72.4 6.0 5.2e-20 72.0 6.0 1.3 1 0 0 1 1 1 1 Yqey-like protein DUF3502 PF12010.8 EJS41651.1 - 0.0036 17.9 1.3 0.0055 17.3 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3502) tRNA_NucTran2_2 PF13735.6 EJS41651.1 - 0.014 15.3 2.7 0.02 14.8 2.7 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DUF5108 PF17133.4 EJS41651.1 - 0.051 13.6 0.2 0.074 13.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5108) Pox_A3L PF05288.11 EJS41651.1 - 0.074 13.1 0.2 0.074 13.1 0.2 2.1 3 0 0 3 3 3 0 Poxvirus A3L Protein MmgE_PrpD PF03972.14 EJS41651.1 - 0.13 10.8 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 MmgE/PrpD family GRAB PF10375.9 EJS41652.1 - 4e-07 29.7 1.6 1.3e-06 28.0 1.6 2.0 1 0 0 1 1 1 1 GRIP-related Arf-binding domain DUF3584 PF12128.8 EJS41652.1 - 0.00049 17.8 31.9 0.00049 17.8 31.9 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3584) GAS PF13851.6 EJS41652.1 - 0.00068 19.1 67.1 0.13 11.6 21.8 4.4 1 1 3 4 4 4 4 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EJS41652.1 - 0.0028 16.6 25.4 0.0028 16.6 25.4 3.8 1 1 4 5 5 5 3 Spc7 kinetochore protein ATG16 PF08614.11 EJS41652.1 - 0.011 15.9 18.4 0.011 15.9 18.4 4.6 1 1 3 4 4 3 0 Autophagy protein 16 (ATG16) DUF1192 PF06698.11 EJS41652.1 - 0.013 15.6 1.7 0.013 15.6 1.7 5.1 5 1 1 6 6 6 0 Protein of unknown function (DUF1192) DUF641 PF04859.12 EJS41652.1 - 0.026 14.9 9.9 0.026 14.9 9.9 5.1 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 EJS41652.1 - 0.054 13.5 38.7 0.11 12.5 5.9 4.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 EJS41652.1 - 0.057 13.5 61.8 0.73 9.9 7.5 5.4 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 EJS41652.1 - 0.9 9.1 61.3 0.056 13.0 21.8 3.8 1 1 3 4 4 4 0 Intermediate filament protein Lebercilin PF15619.6 EJS41652.1 - 0.94 9.1 63.4 0.053 13.2 23.9 3.8 2 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DUF4407 PF14362.6 EJS41652.1 - 1.3 8.3 34.0 0.96 8.7 15.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MbeD_MobD PF04899.12 EJS41652.1 - 2.4 8.3 15.2 1.4 9.1 1.5 4.6 3 1 2 5 5 5 0 MbeD/MobD like Golgin_A5 PF09787.9 EJS41652.1 - 6.6 6.1 63.5 1.5 8.2 21.4 3.8 1 1 3 4 4 4 0 Golgin subfamily A member 5 HIP1_clath_bdg PF16515.5 EJS41652.1 - 8 7.1 61.2 0.094 13.3 16.7 5.6 2 2 4 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc29 PF17082.5 EJS41652.1 - 8.5 6.1 37.7 0.15 11.8 15.5 3.8 1 1 2 3 3 3 0 Spindle Pole Component 29 CENP-F_leu_zip PF10473.9 EJS41652.1 - 8.8 6.4 76.5 0.12 12.4 23.1 4.5 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RFC1 PF08519.12 EJS41653.1 - 1.9e-58 197.1 0.0 1.7e-57 194.0 0.0 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 EJS41653.1 - 1.7e-13 51.2 0.0 3.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 EJS41653.1 - 5.4e-11 42.7 0.2 4.3e-10 39.8 0.0 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 EJS41653.1 - 1.7e-05 24.9 0.0 4.3e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 EJS41653.1 - 1.8e-05 24.5 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EJS41653.1 - 0.00039 20.7 0.0 0.0023 18.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJS41653.1 - 0.00051 20.5 0.0 0.0021 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EJS41653.1 - 0.00069 19.8 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EJS41653.1 - 0.0011 19.3 0.0 0.0036 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_18 PF13238.6 EJS41653.1 - 0.0037 17.8 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EJS41653.1 - 0.0059 17.0 0.0 0.019 15.4 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.6 EJS41653.1 - 0.0063 16.9 0.5 0.022 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EJS41653.1 - 0.0069 16.4 0.0 0.044 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EJS41653.1 - 0.023 14.4 0.0 0.071 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EJS41653.1 - 0.031 14.3 0.0 0.28 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mito_carr PF00153.27 EJS41655.1 - 2.5e-66 219.6 2.3 2.6e-24 85.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EJS41655.1 - 0.44 9.6 3.9 6.2 5.9 0.0 3.6 2 2 2 4 4 4 0 Gammaproteobacterial serine protease Tim17 PF02466.19 EJS41655.1 - 0.69 10.3 3.2 2.5 8.5 3.2 2.3 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Sad1_UNC PF07738.13 EJS41656.1 - 2.2e-31 108.6 0.1 4.6e-31 107.6 0.1 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal PhaP_Bmeg PF09602.10 EJS41656.1 - 0.013 15.4 1.4 0.013 15.4 1.4 2.8 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ISN1 PF06437.11 EJS41657.1 - 5.9e-179 595.2 0.0 6.7e-179 595.1 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Proteasome PF00227.26 EJS41658.1 - 5.4e-49 166.3 0.1 7.7e-49 165.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EJS41658.1 - 2.8e-14 52.2 0.0 2.8e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Xpo1 PF08389.12 EJS41659.1 - 3.2e-26 92.2 4.9 3.2e-26 92.2 4.9 3.8 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 EJS41659.1 - 0.00032 20.5 6.1 0.00045 20.1 2.0 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Choline_transpo PF04515.12 EJS41660.1 - 3.4e-79 266.4 21.5 3.4e-79 266.4 21.5 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF410 PF04190.13 EJS41661.1 - 4.7e-78 262.5 1.4 6.1e-78 262.1 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF2802 PF10975.8 EJS41661.1 - 0.033 14.3 0.3 0.066 13.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) RRM_7 PF16367.5 EJS41661.1 - 0.17 12.0 0.1 0.45 10.7 0.1 1.7 1 0 0 1 1 1 0 RNA recognition motif RHD3 PF05879.12 EJS41662.1 - 1.5e-283 942.5 15.1 1.7e-283 942.4 15.1 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EJS41662.1 - 2.7e-05 23.6 3.8 5e-05 22.7 0.1 2.6 2 1 1 3 3 3 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EJS41662.1 - 2.7e-05 24.3 0.0 0.0001 22.4 0.0 2.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EJS41662.1 - 6e-05 23.1 0.1 0.0002 21.4 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EJS41662.1 - 0.029 14.9 0.2 0.24 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter PIN_4 PF13638.6 EJS41663.1 - 1e-32 113.1 0.3 2.5e-32 111.9 0.3 1.7 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 EJS41663.1 - 0.019 15.3 0.2 0.64 10.3 0.0 2.6 3 0 0 3 3 3 0 PIN like domain Ribosomal_S28e PF01200.18 EJS41664.1 - 1.1e-32 111.8 2.7 1.2e-32 111.7 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.12 EJS41664.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region tRNA-synt_1c PF00749.21 EJS41665.1 - 1.4e-117 392.1 0.0 2.3e-117 391.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 EJS41665.1 - 2e-51 174.2 2.3 3.5e-51 173.4 2.3 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 EJS41665.1 - 4.1e-33 114.7 0.1 1.3e-31 109.8 0.1 2.5 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 EJS41665.1 - 5.6e-16 59.2 4.1 1.4e-15 57.9 4.1 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DAGK_cat PF00781.24 EJS41666.1 - 3.9e-26 91.1 0.0 6.7e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Med4 PF10018.9 EJS41667.1 - 5.7e-35 120.8 2.2 1.9e-34 119.0 1.7 1.9 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DASH_Dad3 PF08656.10 EJS41667.1 - 0.092 12.8 1.9 0.21 11.7 1.4 1.9 1 1 0 1 1 1 0 DASH complex subunit Dad3 MBOAT PF03062.19 EJS41668.1 - 1.1e-83 281.5 8.8 2.1e-83 280.6 8.8 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ferrochelatase PF00762.19 EJS41669.1 - 1e-96 323.8 0.0 1.2e-96 323.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Iso_dh PF00180.20 EJS41670.1 - 5.2e-105 351.4 0.0 6.4e-105 351.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metallophos PF00149.28 EJS41671.1 - 1.7e-12 48.3 0.0 4.3e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UBA PF00627.31 EJS41672.1 - 2.2e-08 33.8 0.0 4.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 EJS41672.1 - 0.00038 20.2 0.0 0.00096 18.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 EJS41672.1 - 0.022 14.5 0.2 0.26 11.0 0.0 2.9 3 1 0 3 3 3 0 CUE domain Sporozoite_P67 PF05642.11 EJS41672.1 - 0.073 11.1 1.8 0.12 10.5 1.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_Rpb4 PF03874.16 EJS41672.1 - 1.6 9.1 5.6 0.26 11.6 0.4 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 Actin PF00022.19 EJS41673.1 - 8.2e-27 93.8 0.0 4e-20 71.8 0.0 3.2 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 EJS41673.1 - 1e-13 51.3 1.8 3.6e-06 26.4 0.3 2.5 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 EJS41673.1 - 0.0006 18.7 0.0 0.014 14.2 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein CoA_binding PF02629.19 EJS41674.1 - 2e-27 95.7 2.6 2.5e-27 95.4 0.7 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EJS41674.1 - 3.7e-23 82.0 0.7 6e-23 81.3 0.7 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EJS41674.1 - 1.9e-07 30.9 0.8 2.8e-07 30.4 0.1 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EJS41674.1 - 3.5e-06 27.5 0.0 7.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain TPK_catalytic PF04263.16 EJS41675.1 - 9.3e-31 106.4 0.3 4.3e-30 104.2 0.3 1.9 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EJS41675.1 - 2.6e-13 49.5 1.9 4.3e-13 48.8 0.2 2.1 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain WTF PF03303.13 EJS41675.1 - 0.005 16.6 0.1 0.01 15.6 0.0 1.5 1 1 0 1 1 1 1 WTF protein LYTB PF02401.18 EJS41675.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 LytB protein KH_8 PF17903.1 EJS41676.1 - 1.1e-06 28.6 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EJS41676.1 - 0.081 12.8 0.2 0.25 11.2 0.2 1.8 1 0 0 1 1 1 0 KH domain RNA_pol_Rpb2_6 PF00562.28 EJS41677.1 - 5.3e-127 424.1 0.2 8.9e-127 423.4 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EJS41677.1 - 4.6e-74 248.3 0.1 7.8e-74 247.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EJS41677.1 - 1.4e-51 174.8 0.0 2.8e-51 173.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EJS41677.1 - 9e-34 115.7 0.1 2e-33 114.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EJS41677.1 - 9e-26 90.0 0.3 2e-25 88.8 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EJS41677.1 - 2.5e-24 85.2 0.1 6.4e-24 83.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EJS41677.1 - 8.8e-20 71.0 1.3 8.8e-20 71.0 1.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Secretin_N_2 PF07655.13 EJS41678.1 - 0.075 13.6 3.4 0.15 12.6 3.4 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain DUF676 PF05057.14 EJS41679.1 - 2.3e-59 200.5 0.0 3.2e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EJS41679.1 - 2e-06 27.7 0.0 3.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 EJS41679.1 - 2.9e-06 27.3 0.0 6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase FSH1 PF03959.13 EJS41679.1 - 0.078 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Sld7_N PF18636.1 EJS41680.1 - 1.1e-39 135.6 0.1 1.9e-39 134.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial morphogenesis protein SLD7 N-terminal domain Sld7_C PF18596.1 EJS41680.1 - 9.7e-21 73.7 0.1 2.2e-20 72.6 0.1 1.6 1 0 0 1 1 1 1 Sld7 C-terminal domain DUF642 PF04862.12 EJS41680.1 - 0.1 12.4 0.3 2.4 7.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF642) Pkinase PF00069.25 EJS41681.1 - 9.2e-58 195.7 0.0 1.2e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41681.1 - 1.3e-16 60.7 0.0 1.9e-16 60.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJS41681.1 - 3.3e-07 30.5 0.0 1.1e-06 28.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJS41681.1 - 0.02 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EJS41681.1 - 0.047 12.5 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EJS41681.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L3 PF00297.22 EJS41683.1 - 4.2e-191 634.7 11.1 4.8e-191 634.6 11.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Cytochrom_C1 PF02167.15 EJS41684.1 - 2e-96 321.9 0.0 2.4e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EJS41684.1 - 0.0012 19.2 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EJS41684.1 - 0.0083 17.2 0.2 0.03 15.4 0.2 2.0 2 1 0 2 2 2 1 Cytochrome c Alg6_Alg8 PF03155.15 EJS41686.1 - 6.2e-164 546.5 37.2 7.4e-164 546.3 37.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Vps5 PF09325.10 EJS41687.1 - 2.1e-77 259.9 11.7 2.1e-77 259.9 11.7 1.7 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EJS41687.1 - 1.2e-23 83.2 0.6 5.1e-23 81.2 0.6 2.1 1 0 0 1 1 1 1 PX domain FliJ PF02050.16 EJS41687.1 - 0.087 13.0 3.2 0.21 11.8 1.6 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein YolD PF08863.10 EJS41687.1 - 0.46 10.6 5.7 0.29 11.2 2.7 2.2 2 0 0 2 2 2 0 YolD-like protein RabGAP-TBC PF00566.18 EJS41688.1 - 1.4e-51 175.2 2.8 1.4e-51 175.2 2.8 2.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Pneumovirus_M2 PF06436.11 EJS41688.1 - 0.018 14.5 0.2 0.058 12.9 0.2 1.9 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) SelP_N PF04592.14 EJS41688.1 - 0.58 9.5 7.8 1.2 8.4 7.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Shugoshin_N PF07558.11 EJS41689.1 - 2.1e-16 59.5 4.7 1.1e-15 57.2 4.7 2.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EJS41689.1 - 1.9e-08 34.0 3.6 1.9e-08 34.0 3.6 2.7 2 0 0 2 2 2 1 Shugoshin C terminus TSC22 PF01166.18 EJS41689.1 - 0.03 14.6 0.5 0.14 12.5 0.5 2.2 1 0 0 1 1 1 0 TSC-22/dip/bun family CHZ PF09649.10 EJS41689.1 - 0.16 11.5 0.2 0.16 11.5 0.2 2.1 2 0 0 2 2 2 0 Histone chaperone domain CHZ Syntaxin-18_N PF10496.9 EJS41690.1 - 2.5e-17 62.9 2.3 2.5e-17 62.9 2.3 2.1 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EJS41690.1 - 3.9e-07 29.9 0.2 5.5e-06 26.3 0.1 2.4 2 0 0 2 2 2 1 SNARE domain DUF3292 PF11696.8 EJS41690.1 - 1 7.7 7.5 0.059 11.7 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) GTP_EFTU PF00009.27 EJS41691.1 - 6.4e-27 94.4 0.0 1.2e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EJS41691.1 - 8e-07 29.1 0.1 7.1e-06 26.1 0.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EJS41691.1 - 0.00089 19.4 1.3 0.34 11.0 0.1 3.0 1 1 1 2 2 2 2 Dynamin family MMR_HSR1_Xtn PF16897.5 EJS41691.1 - 2.6 8.1 5.3 1.4 9.0 0.2 3.1 4 0 0 4 4 4 0 C-terminal region of MMR_HSR1 domain Kin17_mid PF10357.9 EJS41692.1 - 6.6e-33 113.3 0.1 9.7e-33 112.8 0.1 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 EJS41692.1 - 1.9e-05 24.8 2.8 4.1e-05 23.7 2.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJS41692.1 - 0.00031 21.0 3.0 0.00059 20.1 3.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EJS41692.1 - 0.054 13.8 2.9 0.063 13.6 0.3 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) TFIID_NTD2 PF04494.15 EJS41692.1 - 0.18 12.0 0.9 0.39 10.9 0.9 1.6 1 1 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain zf_C2H2_ZHX PF18387.1 EJS41692.1 - 1.1 9.0 3.7 1.1 9.0 0.2 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Zip PF02535.22 EJS41693.1 - 5e-55 187.1 10.4 2.9e-53 181.3 10.4 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3139 PF11337.8 EJS41693.1 - 0.27 11.9 1.4 0.97 10.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Fun_ATP-synt_8 PF05933.13 EJS41693.1 - 1.1 9.5 5.8 3.9 7.7 0.0 3.8 4 0 0 4 4 4 0 Fungal ATP synthase protein 8 (A6L) DUF3336 PF11815.8 EJS41694.1 - 3.4e-32 111.1 2.0 6.1e-32 110.2 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EJS41694.1 - 1.8e-21 77.3 0.0 4e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Whi5 PF08528.11 EJS41695.1 - 7.5e-11 41.4 0.2 1.5e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 Whi5 like PBP1_TM PF14812.6 EJS41695.1 - 1 9.8 6.5 2.2 8.7 0.4 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 EJS41695.1 - 1.3 8.7 9.4 1.9 8.1 0.1 2.7 3 0 0 3 3 3 0 FAM176 family DUF4637 PF15470.6 EJS41695.1 - 1.4 8.7 6.9 5.2 6.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) PTPRCAP PF15713.5 EJS41695.1 - 3 8.1 15.0 4.2 7.6 3.2 2.8 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated Abhydrolase_6 PF12697.7 EJS41696.1 - 7.9e-17 62.6 0.0 1.3e-16 61.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJS41696.1 - 0.00023 20.9 0.6 0.0012 18.6 0.3 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJS41696.1 - 0.00032 20.1 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EJS41696.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 EJS41696.1 - 0.007 16.1 0.0 0.021 14.5 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein OST3_OST6 PF04756.13 EJS41697.1 - 3.7e-77 259.6 7.4 4.3e-77 259.3 7.4 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TcpE PF12648.7 EJS41697.1 - 4.4 7.9 16.6 0.27 11.8 4.3 3.0 2 1 0 2 2 2 0 TcpE family C2 PF00168.30 EJS41698.1 - 1.3e-66 221.4 6.5 4.2e-20 71.9 0.0 4.5 4 0 0 4 4 4 4 C2 domain SMP_LBD PF17047.5 EJS41698.1 - 0.04 13.4 0.1 0.079 12.4 0.1 1.5 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain YfmQ PF10787.9 EJS41698.1 - 2.1 8.1 5.5 13 5.5 0.5 2.7 1 1 1 2 2 2 0 Uncharacterised protein from bacillus cereus group Ion_trans PF00520.31 EJS41699.1 - 0.00032 20.0 22.7 0.0032 16.7 22.7 2.3 1 1 0 1 1 1 1 Ion transport protein Carb_bind PF10645.9 EJS41699.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding PKD_channel PF08016.12 EJS41699.1 - 0.47 9.1 14.9 2 7.0 12.8 2.3 2 1 0 2 2 2 0 Polycystin cation channel Ras PF00071.22 EJS41700.1 - 2.3e-60 202.9 0.0 2.8e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS41700.1 - 9.4e-36 122.7 0.0 1.5e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS41700.1 - 1.5e-17 63.6 0.1 1.8e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EJS41700.1 - 7.3e-08 32.1 0.0 9.6e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJS41700.1 - 1.7e-05 24.8 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJS41700.1 - 3.8e-05 23.3 0.0 4.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EJS41700.1 - 0.00029 20.8 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EJS41700.1 - 0.047 14.1 0.0 0.078 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain PP2C PF00481.21 EJS41701.1 - 1.3e-56 192.1 0.0 2.5e-56 191.2 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Mem_trans PF03547.18 EJS41702.1 - 4.2e-26 91.2 0.0 7.3e-26 90.5 0.0 1.4 1 1 0 1 1 1 1 Membrane transport protein AMP-binding PF00501.28 EJS41703.1 - 2.7e-37 128.4 0.0 5.6e-13 48.3 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme DMAP_binding PF06464.11 EJS41703.1 - 1.2e-20 74.3 3.2 4.4e-20 72.6 3.2 2.1 1 0 0 1 1 1 1 DMAP1-binding Domain Arf PF00025.21 EJS41704.1 - 4.3e-72 241.2 0.2 5e-72 241.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EJS41704.1 - 1.3e-15 57.7 0.1 2e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EJS41704.1 - 2.8e-15 56.2 0.0 3.5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EJS41704.1 - 4.4e-14 52.4 2.5 1.3e-09 37.7 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EJS41704.1 - 2.5e-13 50.0 0.0 3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EJS41704.1 - 6.4e-11 42.1 0.0 8.1e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJS41704.1 - 0.00013 22.0 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EJS41704.1 - 0.11 11.8 0.2 0.2 10.9 0.2 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Rib_5-P_isom_A PF06026.14 EJS41705.1 - 2.9e-58 196.3 0.0 3.6e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EJS41705.1 - 0.0021 18.0 0.0 0.13 12.2 0.0 2.2 1 1 0 1 1 1 1 DeoR C terminal sensor domain Fig1 PF12351.8 EJS41706.1 - 0.094 12.6 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 MAP17 PF15807.5 EJS41706.1 - 0.19 11.9 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Glyco_transf_15 PF01793.16 EJS41707.1 - 1.3e-126 422.3 15.0 1.6e-126 422.0 15.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Mito_carr PF00153.27 EJS41708.1 - 1.6e-58 194.7 4.9 1.4e-20 73.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 EJS41709.1 - 1.5e-56 190.5 0.2 2.1e-56 190.0 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS41709.1 - 1.2e-20 73.9 0.0 2.5e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS41709.1 - 1.7e-08 34.1 0.1 2.2e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EJS41709.1 - 0.00039 20.4 1.4 0.76 9.7 0.0 2.7 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 EJS41709.1 - 0.00043 19.9 0.2 0.0033 17.0 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EJS41709.1 - 0.00043 20.3 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJS41709.1 - 0.0074 15.8 0.3 0.018 14.6 0.3 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EJS41709.1 - 0.02 14.9 0.2 0.071 13.1 0.0 1.9 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain SRP-alpha_N PF04086.13 EJS41709.1 - 9.4 6.1 18.0 3.2 7.6 15.1 1.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DAD PF02109.16 EJS41710.1 - 4.3e-36 123.5 6.4 5.2e-36 123.3 6.4 1.1 1 0 0 1 1 1 1 DAD family DUF2207 PF09972.9 EJS41710.1 - 0.24 10.1 1.2 0.28 9.9 1.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SNARE PF05739.19 EJS41712.1 - 9.3e-14 51.2 2.6 1.9e-13 50.2 2.6 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 EJS41712.1 - 1.4e-06 28.6 1.8 1.4e-06 28.6 1.8 4.1 3 1 0 3 3 3 2 Syntaxin-like protein Synaptobrevin PF00957.21 EJS41712.1 - 7.2e-05 22.5 6.8 0.0002 21.1 1.5 2.6 2 0 0 2 2 2 1 Synaptobrevin Myosin_tail_1 PF01576.19 EJS41712.1 - 0.0023 15.9 14.8 0.0023 15.9 14.8 2.0 2 0 0 2 2 2 1 Myosin tail Rx_N PF18052.1 EJS41712.1 - 0.012 15.8 0.2 0.012 15.8 0.2 2.5 4 0 0 4 4 3 0 Rx N-terminal domain Orf78 PF06024.12 EJS41712.1 - 0.039 14.2 1.2 0.039 14.2 1.2 2.7 1 1 1 2 2 2 0 Orf78 (ac78) ETRAMP PF09716.10 EJS41712.1 - 0.089 12.9 0.2 0.23 11.6 0.2 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) T2SSF PF00482.23 EJS41712.1 - 0.11 12.5 1.3 0.37 10.8 0.0 2.4 2 1 0 3 3 3 0 Type II secretion system (T2SS), protein F UPF0258 PF06789.12 EJS41712.1 - 0.24 11.5 6.5 0.087 12.9 1.3 2.5 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0258) Protamine_P2 PF00841.19 EJS41712.1 - 0.56 10.7 6.3 0.37 11.3 2.3 2.5 2 0 0 2 2 2 0 Sperm histone P2 DUF1664 PF07889.12 EJS41712.1 - 1.3 9.1 12.0 1.3 9.1 5.7 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Neur_chan_memb PF02932.16 EJS41712.1 - 2.3 8.2 11.2 1.3 9.1 8.7 1.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Prominin PF05478.11 EJS41712.1 - 2.9 5.7 16.2 2.4 6.0 12.5 2.0 1 1 1 2 2 2 0 Prominin UPF0242 PF06785.11 EJS41712.1 - 3.7 7.6 34.5 9.8 6.2 0.3 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus EIIBC-GUT_N PF03612.14 EJS41712.1 - 4.5 7.0 7.6 1.2 8.8 3.1 2.1 1 1 1 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Phage_GPO PF05929.11 EJS41712.1 - 6.5 6.3 18.0 1.4 8.4 11.5 2.3 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Syja_N PF02383.18 EJS41713.1 - 1.8e-76 257.5 0.5 3.1e-76 256.7 0.5 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EJS41713.1 - 5.2e-13 49.1 0.0 8.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TFIIIC_sub6 PF10419.9 EJS41714.1 - 1.9e-22 78.9 0.1 5.2e-22 77.5 0.1 1.8 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain His_Phos_1 PF00300.22 EJS41714.1 - 1e-18 67.7 0.0 3.5e-17 62.7 0.0 2.8 2 1 1 3 3 3 1 Histidine phosphatase superfamily (branch 1) Cnd1 PF12717.7 EJS41715.1 - 0.023 14.8 0.8 0.22 11.6 0.7 2.3 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EJS41715.1 - 0.027 14.7 0.0 10 6.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat CLASP_N PF12348.8 EJS41715.1 - 0.054 13.1 0.1 0.69 9.4 0.0 2.4 3 0 0 3 3 3 0 CLASP N terminal DFF-C PF09033.10 EJS41715.1 - 0.098 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain zf-C2H2 PF00096.26 EJS41716.1 - 1.3e-19 69.4 24.5 3.7e-05 23.9 0.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJS41716.1 - 2.6e-19 68.7 22.1 2.8e-08 33.8 0.8 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJS41716.1 - 4.2e-12 45.8 21.8 0.006 17.3 0.3 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 EJS41716.1 - 3.4e-05 24.1 13.3 0.0018 18.6 0.3 4.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EJS41716.1 - 4.5e-05 23.3 23.2 0.0027 17.7 0.4 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJS41716.1 - 8.6e-05 22.7 11.7 0.11 12.9 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EJS41716.1 - 0.00058 20.1 7.6 0.005 17.1 0.3 2.7 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 EJS41716.1 - 0.25 11.4 2.5 1.4 9.0 2.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf_UBZ PF18439.1 EJS41716.1 - 1.1 8.9 4.4 28 4.4 0.0 3.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 EJS41716.1 - 1.7 8.7 16.9 3.9 7.6 0.2 4.5 2 1 1 3 3 3 0 BED zinc finger zf-CHCC PF10276.9 EJS41716.1 - 9.7 6.3 12.6 8 6.6 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger domain DUF1911 PF08929.10 EJS41717.1 - 0.55 11.1 5.2 12 6.7 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) DUF3106 PF11304.8 EJS41717.1 - 3.5 8.2 6.6 4 8.0 2.2 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3106) TRAPP PF04051.16 EJS41718.1 - 3.3e-33 114.5 0.0 5.3e-33 113.8 0.0 1.5 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component RcpB PF16971.5 EJS41718.1 - 0.037 13.9 0.4 0.053 13.4 0.4 1.2 1 0 0 1 1 1 0 Rough colony protein B, tight adherence - tad - subunit RNA_pol_Rpb5_C PF01191.19 EJS41718.1 - 0.14 12.0 0.3 7.8 6.4 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb1_5 PF04998.17 EJS41719.1 - 6.3e-83 278.3 0.1 8.9e-83 277.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EJS41719.1 - 1.4e-79 267.7 0.0 3.3e-79 266.4 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EJS41719.1 - 2.5e-76 255.5 0.3 5.6e-76 254.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EJS41719.1 - 2e-38 131.8 0.0 5.3e-38 130.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EJS41719.1 - 5.5e-31 106.7 0.0 1.3e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 AAA PF00004.29 EJS41720.1 - 5.5e-42 143.3 0.0 1.2e-41 142.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EJS41720.1 - 1.9e-19 69.3 0.4 3.8e-19 68.4 0.4 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EJS41720.1 - 6.6e-09 35.4 0.0 1.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EJS41720.1 - 1.4e-05 25.5 0.1 0.017 15.5 0.0 2.6 1 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EJS41720.1 - 2.6e-05 24.2 1.0 8e-05 22.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EJS41720.1 - 2.8e-05 24.3 0.0 0.00016 21.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EJS41720.1 - 0.00073 19.3 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EJS41720.1 - 0.0011 19.1 0.4 0.02 15.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EJS41720.1 - 0.0028 18.0 2.7 0.06 13.6 0.0 2.8 2 1 1 3 3 2 1 AAA domain PhoH PF02562.16 EJS41720.1 - 0.0054 16.2 0.2 0.061 12.8 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 EJS41720.1 - 0.0099 15.1 0.0 0.019 14.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EJS41720.1 - 0.015 14.7 0.1 0.045 13.1 0.1 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EJS41720.1 - 0.028 14.2 0.5 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EJS41720.1 - 0.03 14.0 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EJS41720.1 - 0.041 14.3 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase DUF1192 PF06698.11 EJS41720.1 - 0.07 13.2 0.9 0.2 11.7 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) AAA_19 PF13245.6 EJS41720.1 - 0.091 13.1 0.5 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJS41720.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EJS41720.1 - 0.12 12.1 0.5 0.29 10.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 EJS41720.1 - 0.17 11.2 1.6 0.32 10.3 0.0 2.2 3 0 0 3 3 3 0 KaiC Atg14 PF10186.9 EJS41720.1 - 0.19 10.8 1.7 0.3 10.1 1.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ThylakoidFormat PF11264.8 EJS41720.1 - 0.21 11.3 2.7 0.44 10.2 2.7 1.5 1 0 0 1 1 1 0 Thylakoid formation protein TolA_bind_tri PF16331.5 EJS41720.1 - 0.35 11.0 8.7 0.53 10.4 5.7 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation Fez1 PF06818.15 EJS41720.1 - 3.9 7.9 8.1 4.1 7.8 4.6 2.3 2 1 0 2 2 2 0 Fez1 TLD PF07534.16 EJS41721.1 - 2.6e-28 99.0 0.2 1.2e-27 96.8 0.1 2.1 2 0 0 2 2 2 1 TLD RIO1 PF01163.22 EJS41722.1 - 7.6e-73 244.1 0.2 7.6e-73 244.1 0.2 2.7 3 0 0 3 3 3 1 RIO1 family Aldo_ket_red PF00248.21 EJS41723.1 - 4.9e-52 176.9 0.0 3.2e-50 171.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Leo1 PF04004.13 EJS41724.1 - 5.9e-48 162.8 0.2 5.9e-48 162.8 0.2 3.2 3 1 0 3 3 3 1 Leo1-like protein UCH PF00443.29 EJS41725.1 - 3.3e-55 187.4 3.9 3.3e-55 187.4 3.9 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EJS41725.1 - 5.1e-40 135.2 15.8 1.3e-16 60.2 0.9 4.9 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.6 EJS41725.1 - 0.0011 18.6 13.5 0.0067 16.1 13.5 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DnaJ PF00226.31 EJS41725.1 - 0.32 11.2 2.7 15 5.8 0.1 3.6 4 0 0 4 4 4 0 DnaJ domain COQ7 PF03232.13 EJS41726.1 - 3.3e-74 248.3 0.0 4.1e-74 248.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EJS41726.1 - 0.091 13.2 0.0 0.17 12.2 0.0 1.5 2 0 0 2 2 2 0 Rubrerythrin TAL_FSA PF00923.19 EJS41726.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase Lipase_GDSL_2 PF13472.6 EJS41727.1 - 3.3e-21 76.5 0.0 4.7e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EJS41727.1 - 1.4e-15 57.8 0.0 1.9e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Chlam_OMP PF01308.17 EJS41727.1 - 0.067 12.0 0.0 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 Chlamydia major outer membrane protein RhoGAP PF00620.27 EJS41728.1 - 3.9e-46 156.6 0.6 1.3e-45 155.0 0.1 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EJS41728.1 - 3.7e-10 39.9 30.6 1.6e-05 25.0 12.1 2.7 2 0 0 2 2 2 2 LIM domain TolA_bind_tri PF16331.5 EJS41728.1 - 0.082 13.0 0.9 0.27 11.4 0.9 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation APG6_N PF17675.1 EJS41728.1 - 0.36 11.3 22.3 0.021 15.3 15.6 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Ribosomal_S2 PF00318.20 EJS41728.1 - 9.1 5.4 6.9 1 8.5 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S2 AIRC PF00731.20 EJS41729.1 - 2.9e-62 208.6 1.5 5.3e-62 207.8 1.5 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EJS41729.1 - 4.8e-61 205.3 0.0 9.1e-61 204.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EJS41729.1 - 3.7e-18 65.0 0.0 6.6e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain AlaDh_PNT_C PF01262.21 EJS41729.1 - 0.00023 20.5 0.0 0.00052 19.4 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EJS41729.1 - 0.00032 20.1 0.0 0.00073 18.9 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.17 EJS41729.1 - 0.0036 16.8 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 EJS41729.1 - 0.004 16.7 0.0 0.022 14.3 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 3HCDH_N PF02737.18 EJS41729.1 - 0.077 12.9 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mito_carr PF00153.27 EJS41730.1 - 5.4e-57 189.7 3.8 7.5e-20 70.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.24 EJS41731.1 - 3.2e-11 43.2 0.3 8.9e-11 41.8 0.3 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EJS41731.1 - 0.016 14.7 10.8 0.036 13.6 10.8 1.5 1 0 0 1 1 1 0 Vps5 C terminal like WSC PF01822.19 EJS41732.1 - 1.3e-11 44.5 15.5 1.3e-11 44.5 15.5 3.0 2 1 0 2 2 2 1 WSC domain DUF456 PF04306.13 EJS41732.1 - 0.014 15.7 0.3 0.02 15.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) TFIIA PF03153.13 EJS41732.1 - 0.07 13.1 7.5 0.088 12.8 7.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.13 EJS41732.1 - 0.22 10.0 5.4 0.27 9.8 5.4 1.2 1 0 0 1 1 1 0 Utp14 protein Gly-zipper_Omp PF13488.6 EJS41732.1 - 0.35 10.9 12.0 0.64 10.1 12.0 1.3 1 0 0 1 1 1 0 Glycine zipper Sec3_C PF09763.9 EJS41732.1 - 0.54 8.6 4.2 0.82 8.0 4.2 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 Pacs-1 PF10254.9 EJS41732.1 - 9.9 5.0 12.1 16 4.4 12.1 1.4 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein SRP1_TIP1 PF00660.17 EJS41733.1 - 4.3e-32 110.1 0.2 4.3e-32 110.1 0.2 2.2 2 0 0 2 2 2 1 Seripauperin and TIP1 family DUF963 PF06131.11 EJS41733.1 - 0.00097 18.5 20.7 0.00097 18.5 20.7 9.7 3 2 7 10 10 10 4 Schizosaccharomyces pombe repeat of unknown function (DUF963) C1_1 PF00130.22 EJS41733.1 - 0.29 11.0 3.1 0.42 10.5 2.1 1.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2757 PF10955.8 EJS41733.1 - 0.5 10.7 2.1 25 5.2 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) SRP1_TIP1 PF00660.17 EJS41734.1 - 4.9e-33 113.2 0.1 1.6e-32 111.5 0.1 1.8 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.19 EJS41734.1 - 5e-07 29.1 7.4 5e-07 29.1 7.4 4.2 5 0 0 5 5 5 1 Yeast PIR protein repeat Spc42p PF11544.8 EJS41734.1 - 0.016 15.2 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p Hamartin PF04388.12 EJS41734.1 - 1.9 7.0 11.7 2.1 6.9 11.7 1.1 1 0 0 1 1 1 0 Hamartin protein SOBP PF15279.6 EJS41734.1 - 2.5 8.6 7.1 3.6 8.1 7.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF572 PF04502.13 EJS41734.1 - 2.8 7.5 6.9 3 7.4 6.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RIFIN PF02009.16 EJS41734.1 - 2.8 7.7 14.0 2 8.2 10.7 2.0 2 0 0 2 2 2 0 Rifin Macoilin PF09726.9 EJS41734.1 - 6.1 5.3 15.0 8.9 4.7 15.0 1.2 1 0 0 1 1 1 0 Macoilin family CCDC84 PF14968.6 EJS41734.1 - 8.5 5.9 6.5 11 5.5 6.5 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 ABC2_membrane PF01061.24 EJS41735.1 - 1.2e-63 214.3 54.4 4.5e-35 121.0 26.6 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EJS41735.1 - 1.2e-29 103.5 0.0 4.3e-15 56.4 0.1 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EJS41735.1 - 4e-27 94.0 17.4 3.6e-24 84.5 0.2 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 EJS41735.1 - 7e-11 41.8 44.3 2.8e-05 23.4 21.0 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EJS41735.1 - 4.9e-05 23.3 0.2 0.00011 22.1 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EJS41735.1 - 0.00013 21.9 0.1 0.075 12.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EJS41735.1 - 0.0038 17.7 0.0 0.0092 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJS41735.1 - 0.0089 16.4 0.1 0.022 15.2 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EJS41735.1 - 0.0098 15.3 0.5 0.65 9.4 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EJS41735.1 - 0.017 15.7 0.0 0.04 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EJS41735.1 - 0.057 13.2 0.4 0.14 11.9 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EJS41735.1 - 0.064 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EJS41735.1 - 0.09 12.3 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain SPC25 PF06703.11 EJS41735.1 - 0.091 12.5 0.1 0.091 12.5 0.1 2.8 2 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) MMR_HSR1 PF01926.23 EJS41735.1 - 0.11 12.6 0.2 0.67 10.1 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 EJS41735.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain B56 PF01603.20 EJS41736.1 - 3.5e-174 579.6 9.0 5.7e-174 579.0 9.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cpn10 PF00166.21 EJS41738.1 - 3.2e-27 94.4 0.3 3.6e-27 94.3 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit ATP19 PF11022.8 EJS41739.1 - 5.2e-19 68.4 0.1 6.2e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit K M-inducer_phosp PF06617.13 EJS41739.1 - 0.0047 16.3 0.2 0.0051 16.2 0.2 1.0 1 0 0 1 1 1 1 M-phase inducer phosphatase CLN3 PF02487.17 EJS41739.1 - 0.14 11.2 0.1 0.15 11.1 0.1 1.0 1 0 0 1 1 1 0 CLN3 protein RNA_Me_trans PF04252.13 EJS41740.1 - 2.5e-80 268.8 0.0 2.9e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase WD40 PF00400.32 EJS41741.1 - 7.8e-07 29.7 2.7 0.0022 18.8 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat WD40_like PF17005.5 EJS41741.1 - 2.2e-05 23.9 0.8 0.18 11.1 0.0 2.9 1 1 1 2 2 2 2 WD40-like domain Nucleoporin_N PF08801.11 EJS41741.1 - 0.00017 20.5 0.1 0.52 9.0 0.1 2.4 2 1 0 2 2 2 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 EJS41741.1 - 0.00027 21.2 0.0 0.089 13.1 0.0 3.8 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJS41741.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 EJS41741.1 - 0.026 15.0 0.0 92 3.7 0.0 4.6 4 1 1 5 5 5 0 PQQ-like domain PHTB1_N PF14727.6 EJS41741.1 - 0.027 13.8 0.0 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 PTHB1 N-terminus TPR_1 PF00515.28 EJS41742.1 - 1.5e-47 157.6 20.9 8.1e-08 31.8 0.3 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 EJS41742.1 - 1.1e-34 118.1 16.1 1.5e-18 66.4 5.1 2.8 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 EJS41742.1 - 2.6e-33 111.4 23.0 1.3e-06 28.1 0.3 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 EJS41742.1 - 1.4e-21 76.5 12.5 2.3e-06 27.8 0.6 6.4 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EJS41742.1 - 3.8e-20 70.4 21.4 8.3e-06 25.6 0.2 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EJS41742.1 - 2.5e-18 65.5 28.2 0.005 16.5 0.1 9.1 7 2 2 9 9 9 7 TPR repeat TPR_16 PF13432.6 EJS41742.1 - 9.4e-16 58.2 8.2 0.00015 22.4 0.0 6.4 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EJS41742.1 - 4.8e-14 51.9 7.9 0.29 12.1 0.1 8.3 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EJS41742.1 - 7e-14 51.1 11.5 0.024 15.0 0.1 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 EJS41742.1 - 7.6e-14 50.6 11.4 0.0037 17.2 0.2 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EJS41742.1 - 1.3e-12 48.0 22.0 0.00012 22.5 1.2 6.9 5 3 1 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 EJS41742.1 - 1.4e-09 37.5 7.8 0.051 13.5 0.3 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EJS41742.1 - 1.1e-06 28.6 4.3 0.00094 19.3 0.0 4.7 5 2 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EJS41742.1 - 7.7e-05 22.9 13.4 0.011 16.0 0.2 4.5 3 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.9 EJS41742.1 - 0.00015 20.6 3.6 0.00039 19.3 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_6 PF13174.6 EJS41742.1 - 0.0002 21.8 20.1 2.3 9.0 0.0 8.1 9 0 0 9 9 7 1 Tetratricopeptide repeat Pterin_4a PF01329.19 EJS41742.1 - 0.049 13.8 0.3 11 6.2 0.1 3.3 2 1 1 3 3 3 0 Pterin 4 alpha carbinolamine dehydratase SHNi-TPR PF10516.9 EJS41742.1 - 0.14 11.6 9.2 3 7.4 0.0 5.7 7 0 0 7 7 7 0 SHNi-TPR TPR_20 PF14561.6 EJS41742.1 - 0.22 11.9 13.9 0.31 11.4 0.6 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat XPC-binding PF09280.11 EJS41742.1 - 0.92 9.3 7.8 0.14 12.0 2.6 2.4 3 0 0 3 3 2 0 XPC-binding domain MAS20 PF02064.15 EJS41742.1 - 1.5 9.0 0.0 1.5 9.0 0.0 4.6 4 1 2 6 6 6 0 MAS20 protein import receptor TPR_4 PF07721.14 EJS41742.1 - 2 9.2 6.6 1.9 9.4 0.5 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat bZIP_1 PF00170.21 EJS41743.1 - 7.5e-13 48.4 13.4 1.2e-12 47.7 13.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor Hemagglutinin PF00509.18 EJS41743.1 - 0.024 13.1 0.7 0.032 12.6 0.7 1.2 1 0 0 1 1 1 0 Haemagglutinin HALZ PF02183.18 EJS41743.1 - 0.039 14.2 1.7 0.074 13.3 1.7 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_Maf PF03131.17 EJS41743.1 - 0.49 11.0 8.5 0.95 10.0 8.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 EJS41743.1 - 7.4 6.7 16.4 1.3 9.1 12.6 1.7 2 0 0 2 2 2 0 Basic region leucine zipper PalH PF08733.10 EJS41744.1 - 2.9e-99 332.2 28.2 3.6e-99 331.9 28.2 1.1 1 0 0 1 1 1 1 PalH/RIM21 Metallothi_Euk2 PF12809.7 EJS41745.1 - 1.5e-37 127.7 55.3 1.7e-37 127.5 55.3 1.0 1 0 0 1 1 1 1 Eukaryotic metallothionein HLH PF00010.26 EJS41746.1 - 5.4e-19 67.9 0.3 1.3e-18 66.7 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Syntaxin_2 PF14523.6 EJS41747.1 - 3.5e-25 88.3 11.0 1.8e-22 79.6 5.4 2.3 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 EJS41747.1 - 6.8e-15 54.8 0.3 1.6e-14 53.6 0.3 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EJS41747.1 - 3.3e-05 23.7 17.9 7e-05 22.6 17.9 1.7 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 EJS41747.1 - 0.0022 17.8 2.0 0.0022 17.8 2.0 2.8 4 0 0 4 4 4 1 Synaptobrevin DUF722 PF05263.11 EJS41747.1 - 0.012 15.8 6.0 0.057 13.6 1.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF722) DUF16 PF01519.16 EJS41747.1 - 0.019 15.4 3.5 0.019 15.4 3.5 3.1 2 1 0 2 2 2 0 Protein of unknown function DUF16 Use1 PF09753.9 EJS41747.1 - 0.049 13.4 10.5 0.067 12.9 10.5 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 BLOC1_2 PF10046.9 EJS41747.1 - 0.067 13.5 12.5 0.44 10.9 0.2 3.8 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V-SNARE PF05008.15 EJS41747.1 - 0.067 13.6 6.7 0.41 11.0 0.3 3.0 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus FAM76 PF16046.5 EJS41747.1 - 0.28 10.5 10.1 0.15 11.4 7.9 1.7 1 1 1 2 2 2 0 FAM76 protein CdvA PF18822.1 EJS41747.1 - 0.31 10.9 11.4 1.2 8.9 0.5 3.9 1 1 2 3 3 3 0 CdvA-like coiled-coil domain RNA_pol_Rpb1_5 PF04998.17 EJS41747.1 - 1.8 8.0 6.8 2.5 7.5 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Fib_alpha PF08702.10 EJS41747.1 - 4.2 7.5 18.5 2.7 8.2 0.6 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 EJS41747.1 - 4.6 7.6 14.0 9.6 6.5 0.6 4.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) CEP209_CC5 PF16574.5 EJS41747.1 - 4.9 7.3 11.4 5.5 7.2 7.0 2.9 1 1 1 2 2 2 0 Coiled-coil region of centrosome protein CE290 DUF1664 PF07889.12 EJS41747.1 - 8.3 6.5 13.2 5.8 7.0 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4665 PF15679.5 EJS41747.1 - 9 7.0 9.6 1.8 9.2 3.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) MSC PF09402.10 EJS41747.1 - 9.1 5.6 9.3 53 3.1 9.3 2.0 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain FAD_binding_6 PF00970.24 EJS41748.1 - 1.2e-06 28.8 0.1 1.3e-05 25.4 0.0 2.5 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain CK_II_beta PF01214.18 EJS41749.1 - 1.5e-71 240.0 0.1 1.8e-71 239.8 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HAGH_C PF16123.5 EJS41750.1 - 1.6e-16 60.6 0.0 2.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EJS41750.1 - 2.9e-12 47.0 0.1 5.8e-11 42.8 0.1 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EJS41750.1 - 8.1e-05 22.2 0.1 0.00013 21.6 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CUE PF02845.16 EJS41751.1 - 1.1e-10 41.0 0.0 2.2e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain T4-gp15_tss PF16724.5 EJS41752.1 - 0.04 13.7 0.0 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 T4-like virus Myoviridae tail sheath stabiliser Tom6 PF17112.5 EJS41754.1 - 1.7e-27 94.7 1.7 2.1e-27 94.3 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal DEAD PF00270.29 EJS41755.1 - 2.3e-36 125.2 0.8 3.7e-36 124.5 0.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS41755.1 - 1.5e-28 99.4 0.1 4.7e-28 97.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS41755.1 - 6.2e-07 29.6 0.9 1.6e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EJS41755.1 - 0.0043 16.8 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EJS41755.1 - 0.029 14.6 0.3 0.094 13.0 0.1 1.9 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.6 EJS41755.1 - 2.8 7.2 8.7 0.36 10.1 0.1 2.9 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit STD1 PF17235.2 EJS41756.1 - 4.8e-73 245.2 0.3 4.8e-73 245.2 0.3 1.5 2 0 0 2 2 2 1 STD1/MTH1 XRN_M PF17846.1 EJS41757.1 - 1.8e-130 435.8 1.4 1.2e-96 324.4 0.2 2.8 3 1 1 4 4 4 2 Xrn1 helical domain XRN_N PF03159.18 EJS41757.1 - 1.9e-99 332.0 0.3 1.1e-98 329.5 0.0 2.5 4 0 0 4 4 4 1 XRN 5'-3' exonuclease N-terminus zf-AN1 PF01428.16 EJS41758.1 - 2e-09 37.4 12.3 3.9e-09 36.5 12.3 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EJS41758.1 - 0.016 15.5 7.4 0.029 14.7 7.4 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain CDK2AP PF09806.9 EJS41758.1 - 0.76 9.8 5.0 0.78 9.8 4.4 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PIN_6 PF17146.4 EJS41759.1 - 8.7e-31 106.3 0.1 2.3e-30 105.0 0.1 1.8 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EJS41759.1 - 8.6e-25 86.7 1.5 1.6e-24 85.9 0.7 1.9 1 1 1 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like Nop25 PF09805.9 EJS41759.1 - 0.015 15.7 13.4 0.015 15.7 13.4 2.4 2 1 1 3 3 3 0 Nucleolar protein 12 (25kDa) DUF4407 PF14362.6 EJS41759.1 - 8.4 5.7 8.4 14 4.9 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SGS PF05002.15 EJS41760.1 - 3.6e-30 103.9 0.5 3.6e-30 103.9 0.5 2.3 2 0 0 2 2 2 1 SGS domain CS PF04969.16 EJS41760.1 - 1.1e-11 45.5 0.4 2.7e-11 44.3 0.4 1.7 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 EJS41760.1 - 0.0035 17.3 1.3 0.2 11.8 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat UxaC PF02614.14 EJS41760.1 - 0.026 13.4 0.1 0.039 12.8 0.1 1.2 1 0 0 1 1 1 0 Glucuronate isomerase TPR_1 PF00515.28 EJS41760.1 - 0.043 13.7 1.6 0.37 10.7 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJS41760.1 - 0.14 12.5 0.2 0.43 10.9 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EJS41760.1 - 0.36 11.1 2.7 1.5 9.1 0.4 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MAP65_ASE1 PF03999.12 EJS41761.1 - 5.3e-188 626.5 41.5 8.4e-188 625.8 41.5 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DLP_helical PF18709.1 EJS41761.1 - 8.4e-05 21.9 1.6 8.4e-05 21.9 1.6 2.5 2 1 0 2 2 2 1 Dynamin-like helical domain DHHC PF01529.20 EJS41762.1 - 1.1e-32 112.9 11.2 1.1e-32 112.9 11.2 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase HlyIII PF03006.20 EJS41763.1 - 7.4e-59 199.2 19.3 8.8e-59 198.9 19.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related Cyclin PF08613.11 EJS41764.1 - 3.9e-41 141.1 2.1 3.3e-40 138.1 2.1 2.2 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EJS41764.1 - 0.068 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain DNA_pol_A_exo1 PF01612.20 EJS41765.1 - 9.9e-48 162.2 0.4 2.4e-47 160.9 0.4 1.7 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EJS41765.1 - 1.1e-19 70.8 5.0 7.9e-19 68.1 2.2 2.8 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EJS41765.1 - 1.1e-10 41.4 0.0 2.3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 HRDC domain DUF5085 PF16895.5 EJS41765.1 - 0.071 13.4 0.3 0.15 12.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5085) Alg6_Alg8 PF03155.15 EJS41766.1 - 5e-143 477.6 28.2 6.4e-143 477.2 28.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Peptidase_S8 PF00082.22 EJS41767.1 - 2.7e-31 109.0 6.1 7.6e-31 107.5 6.1 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EJS41767.1 - 6.9e-12 45.9 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DNA_ligase_A_M PF01068.21 EJS41768.1 - 4.6e-54 183.2 0.0 7.7e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EJS41768.1 - 1.1e-22 81.2 0.0 3.2e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 EJS41768.1 - 1.8e-15 57.1 0.5 6.2e-09 36.1 0.1 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EJS41768.1 - 2.4e-13 50.3 0.5 1.2e-06 28.7 0.1 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RNA_ligase PF09414.10 EJS41768.1 - 5.6e-10 39.8 0.0 1.1e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 EJS41768.1 - 0.0017 18.9 0.0 0.0046 17.5 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 EJS41768.1 - 0.0079 16.0 1.4 1.8 8.3 0.0 2.8 3 0 0 3 3 3 2 mRNA capping enzyme, catalytic domain Fve PF09259.11 EJS41768.1 - 0.11 12.6 0.0 0.72 10.0 0.0 2.2 2 0 0 2 2 2 0 Fungal immunomodulatory protein Fve SGTA_dimer PF16546.5 EJS41769.1 - 4.6e-21 74.4 1.5 1.3e-20 73.0 1.5 1.8 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 EJS41769.1 - 9.9e-19 66.3 6.3 1e-06 28.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJS41769.1 - 1.5e-16 59.1 8.3 1.8e-05 24.5 0.2 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EJS41769.1 - 2.9e-14 52.4 9.5 5.2e-05 22.8 2.4 3.5 1 1 2 3 3 3 3 TPR repeat TPR_10 PF13374.6 EJS41769.1 - 3.4e-08 33.1 3.2 0.016 15.1 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJS41769.1 - 5.4e-08 32.4 8.8 0.0057 16.8 0.4 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EJS41769.1 - 6.8e-08 33.0 3.3 5e-05 23.9 0.2 2.6 2 1 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EJS41769.1 - 7e-08 32.6 1.5 6.4e-05 23.2 0.5 3.4 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EJS41769.1 - 1.8e-07 31.4 0.3 0.058 14.2 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EJS41769.1 - 5.4e-07 29.5 2.3 0.0012 19.0 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJS41769.1 - 4.4e-06 27.1 4.1 0.0031 18.0 0.2 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EJS41769.1 - 9e-05 22.2 1.3 5.3 7.3 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EJS41769.1 - 0.00032 21.2 2.3 0.079 13.6 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 EJS41769.1 - 0.00038 20.9 0.2 0.0024 18.3 0.1 2.1 1 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 EJS41769.1 - 0.0015 18.7 0.1 0.19 11.9 0.0 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat STI1 PF17830.1 EJS41769.1 - 0.0095 15.9 13.3 0.17 11.8 12.0 2.6 1 1 1 2 2 2 2 STI1 domain Fis1_TPR_C PF14853.6 EJS41769.1 - 0.015 15.3 1.7 2.9 8.0 0.1 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EJS41769.1 - 0.23 11.6 11.2 0.28 11.3 0.2 3.9 2 2 1 3 3 3 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 EJS41769.1 - 1 9.4 4.6 2.1 8.4 1.3 3.1 2 1 1 3 3 2 0 Domain of Unknown Function (DUF3856) GTP_EFTU PF00009.27 EJS41771.1 - 2.3e-31 108.9 3.3 1e-29 103.5 3.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EJS41771.1 - 1.5e-26 92.6 0.5 4e-26 91.2 0.5 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 EJS41771.1 - 2.5e-09 36.8 0.0 7.7e-09 35.2 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 EJS41771.1 - 7.3e-09 35.7 0.3 2.2e-08 34.2 0.3 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJS41771.1 - 0.00011 22.1 2.5 0.0044 17.0 0.5 2.9 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU_D2 PF03144.25 EJS41771.1 - 0.00072 19.9 0.8 0.22 11.9 0.1 3.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Ras PF00071.22 EJS41771.1 - 0.035 13.7 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Ras family Dynamin_N PF00350.23 EJS41771.1 - 0.036 14.1 4.3 4.4 7.3 0.0 3.6 2 2 1 3 3 3 0 Dynamin family DUF2095 PF09868.9 EJS41771.1 - 0.069 13.1 0.1 0.5 10.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) PDCD2_C PF04194.13 EJS41772.1 - 6.3e-40 137.1 0.2 1.1e-37 129.8 0.0 2.9 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain Rrp44_CSD1 PF17216.3 EJS41773.1 - 2.7e-98 325.7 0.2 6.2e-98 324.5 0.2 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain RNB PF00773.19 EJS41773.1 - 1e-97 327.4 0.0 1.6e-97 326.8 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 EJS41773.1 - 2.2e-29 101.2 1.8 2.8e-29 100.9 0.2 2.0 2 0 0 2 2 2 1 S1 domain OB_Dis3 PF17849.1 EJS41773.1 - 1.3e-16 60.4 0.0 3.3e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EJS41773.1 - 1.9e-15 57.3 0.2 4.7e-15 56.0 0.2 1.6 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 EJS41773.1 - 1.9e-05 24.7 0.0 0.022 14.9 0.0 3.1 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 EJS41773.1 - 0.046 13.4 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease B OB domain Dis3l2_C_term PF17877.1 EJS41773.1 - 0.17 12.2 0.2 0.45 10.9 0.2 1.7 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal AA_permease PF00324.21 EJS41774.1 - 2e-121 405.9 43.2 2.4e-121 405.7 43.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS41774.1 - 9.1e-34 117.0 45.2 1.1e-33 116.7 45.2 1.1 1 0 0 1 1 1 1 Amino acid permease YMF19 PF02326.15 EJS41774.1 - 3.2 8.6 5.7 5.3 7.9 0.1 3.1 3 0 0 3 3 3 0 Plant ATP synthase F0 SUR7 PF06687.12 EJS41775.1 - 1.6e-18 67.1 16.4 2.6e-18 66.4 16.4 1.3 1 0 0 1 1 1 1 SUR7/PalI family EMP70 PF02990.16 EJS41775.1 - 0.077 11.7 6.8 0.15 10.7 6.8 1.4 1 0 0 1 1 1 0 Endomembrane protein 70 PAT1 PF09770.9 EJS41775.1 - 2.6 6.2 19.8 3.3 5.9 19.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Histone PF00125.24 EJS41777.1 - 1.7e-16 60.8 0.0 2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EJS41777.1 - 2.1e-13 49.8 0.3 3.8e-13 48.9 0.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EJS41777.1 - 0.00013 22.1 0.0 0.00018 21.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PLA2_B PF01735.18 EJS41778.1 - 9.6e-230 763.1 1.2 1.2e-229 762.8 1.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 EJS41778.1 - 0.0074 16.5 1.4 0.016 15.4 1.4 1.5 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain RTC PF01137.21 EJS41779.1 - 2.1e-43 148.1 0.0 2.4e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EJS41779.1 - 3e-29 101.5 0.0 5e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CAT_RBD PF03123.15 EJS41779.1 - 0.025 14.5 0.3 0.073 13.0 0.3 1.7 1 0 0 1 1 1 0 CAT RNA binding domain LapA_dom PF06305.11 EJS41780.1 - 0.042 13.7 0.2 0.078 12.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Topoisom_I PF01028.20 EJS41781.1 - 1.1e-97 325.9 1.3 1.1e-97 325.9 1.3 2.8 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EJS41781.1 - 1.4e-96 322.1 0.4 1.4e-96 322.1 0.4 3.6 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EJS41781.1 - 1.8e-33 114.3 0.7 1.8e-33 114.3 0.7 2.6 2 0 0 2 2 2 1 C-terminal topoisomerase domain Zip PF02535.22 EJS41781.1 - 0.87 8.7 6.7 1.8 7.7 6.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_M49 PF03571.15 EJS41782.1 - 1.1e-227 756.8 0.0 1.6e-227 756.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M49 DUF1027 PF06265.11 EJS41782.1 - 0.34 10.9 2.2 0.84 9.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1027) His_Phos_1 PF00300.22 EJS41783.1 - 1.2e-31 110.0 0.0 8.2e-18 64.8 0.2 3.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF3530 PF12048.8 EJS41783.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) zf-C3HC4_4 PF15227.6 EJS41784.1 - 1.6e-09 37.8 10.7 1.6e-09 37.8 10.7 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EJS41784.1 - 2.4e-08 33.7 5.5 2.4e-08 33.7 5.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJS41784.1 - 2.7e-08 33.5 9.5 2.7e-08 33.5 9.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJS41784.1 - 4.5e-08 33.0 6.6 4.5e-08 33.0 6.6 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EJS41784.1 - 3.2e-07 30.6 8.6 3.2e-07 30.6 8.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJS41784.1 - 2.1e-06 27.4 9.6 2.1e-06 27.4 9.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJS41784.1 - 1.9e-05 24.6 8.3 1.9e-05 24.6 8.3 2.6 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EJS41784.1 - 7.6e-05 22.5 6.2 7.6e-05 22.5 6.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zinc_ribbon_2 PF13240.6 EJS41784.1 - 0.0012 18.5 1.3 0.05 13.3 0.3 3.1 2 1 0 2 2 2 1 zinc-ribbon domain HypA PF01155.19 EJS41784.1 - 0.0028 17.6 5.8 0.095 12.7 0.1 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ANAPC11 PF12861.7 EJS41784.1 - 0.036 14.1 1.9 0.036 14.1 1.9 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EJS41784.1 - 0.037 14.3 6.5 0.037 14.3 6.5 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zinc-ribbons_6 PF07191.12 EJS41784.1 - 0.039 13.9 6.4 2.6 8.1 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 EJS41784.1 - 0.12 12.4 12.1 0.81 9.8 0.9 2.7 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 EJS41784.1 - 0.93 9.8 17.7 0.2 11.9 2.3 3.5 3 1 0 3 3 2 0 zinc-ribbon zf-3CxxC_2 PF17180.4 EJS41784.1 - 2 9.2 7.0 1.6 9.5 2.5 2.9 2 0 0 2 2 2 0 Zinc-binding domain Cytochrome_C7 PF14522.6 EJS41784.1 - 2.9 7.9 9.6 5.4 7.1 0.4 2.9 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c Zn-ribbon_8 PF09723.10 EJS41784.1 - 3 8.1 10.3 12 6.1 1.1 3.0 2 1 0 2 2 2 0 Zinc ribbon domain zf-RING_4 PF14570.6 EJS41784.1 - 3.7 7.4 17.6 1.2 9.0 7.1 3.1 2 2 0 2 2 2 0 RING/Ubox like zinc-binding domain Cytochrom_c3_2 PF14537.6 EJS41784.1 - 3.7 8.1 8.6 3.2 8.3 0.2 3.4 2 1 0 2 2 2 0 Cytochrome c3 zf-ribbon_3 PF13248.6 EJS41784.1 - 5.8 6.5 9.6 21 4.7 5.3 3.3 2 1 0 2 2 2 0 zinc-ribbon domain RNHCP PF12647.7 EJS41784.1 - 7.3 6.6 8.2 7.4 6.6 0.2 2.7 2 1 0 2 2 2 0 RNHCP domain YjbE PF11106.8 EJS41785.1 - 0.18 12.1 6.9 0.19 11.9 6.9 1.0 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE SAM_decarbox PF01536.16 EJS41786.1 - 3.7e-126 420.9 4.6 4.3e-126 420.7 4.6 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Tfb5 PF06331.12 EJS41786.1 - 0.033 14.2 0.4 0.39 10.7 0.1 2.5 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 Gal11_ABD1 PF18535.1 EJS41787.1 - 5.6e-39 132.1 19.6 5.6e-39 132.1 19.6 8.2 4 2 1 5 5 5 1 Gal11 activator-binding domain (ABD1) Med15_fungi PF05397.12 EJS41787.1 - 2.9e-32 111.2 5.1 2.9e-32 111.2 5.1 7.6 5 3 2 7 7 7 1 Mediator complex subunit 15 KIX_2 PF16987.5 EJS41787.1 - 9.8e-18 63.9 0.8 9.8e-18 63.9 0.8 6.6 6 2 1 7 7 7 1 KIX domain GSH_synth_ATP PF03917.17 EJS41788.1 - 5.5e-126 420.3 0.1 6.3e-126 420.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EJS41788.1 - 1.1e-31 109.3 0.2 2.4e-31 108.2 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase CppA_C PF14507.6 EJS41788.1 - 0.072 13.8 0.4 0.22 12.3 0.4 1.8 1 0 0 1 1 1 0 CppA C-terminal Pkinase PF00069.25 EJS41789.1 - 2.6e-61 207.3 0.3 4.4e-61 206.6 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41789.1 - 2.8e-23 82.6 0.0 4.6e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS41789.1 - 3.1e-09 36.5 0.0 6.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EJS41789.1 - 0.0075 15.1 0.8 0.015 14.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EJS41789.1 - 0.0079 15.6 0.2 0.014 14.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.25 EJS41789.1 - 0.028 14.4 0.0 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 PAS fold APH PF01636.23 EJS41789.1 - 0.032 14.2 0.2 0.065 13.1 0.3 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EJS41789.1 - 0.22 11.1 1.0 0.33 10.5 0.1 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-NOSIP PF15906.5 EJS41790.1 - 0.14 12.4 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein HhH-GPD PF00730.25 EJS41791.1 - 1.2e-21 77.2 0.0 2.2e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EJS41791.1 - 4e-05 23.3 0.0 0.00062 19.5 0.0 3.0 4 0 0 4 4 4 1 Helix-hairpin-helix motif Exo_endo_phos PF03372.23 EJS41792.1 - 5.9e-13 48.9 0.4 1.5e-12 47.6 0.4 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 EJS41793.1 - 1.2e-17 63.5 1.7 2.4e-14 52.9 0.1 4.3 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJS41793.1 - 0.00027 21.0 0.4 0.27 11.4 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EJS41793.1 - 0.013 15.5 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ribosomal_S19 PF00203.21 EJS41794.1 - 1.2e-32 111.7 0.2 6.4e-32 109.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 EJS41795.1 - 1.9e-25 89.3 12.7 2.2e-25 89.0 12.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Proteasome PF00227.26 EJS41796.1 - 5.5e-57 192.3 0.0 7.3e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJS41796.1 - 2.2e-13 49.6 0.2 5.9e-13 48.2 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RT_RNaseH PF17917.1 EJS41797.1 - 0.25 11.7 1.3 1.2 9.4 0.0 2.6 2 1 1 3 3 3 0 RNase H-like domain found in reverse transcriptase DUF775 PF05603.12 EJS41798.1 - 3.3e-63 212.8 0.1 3.8e-63 212.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) SIL1 PF16782.5 EJS41799.1 - 2.4e-103 345.4 12.4 2.9e-103 345.1 12.4 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 SYF2 PF08231.12 EJS41799.1 - 0.13 12.6 4.1 0.049 14.0 1.0 1.8 2 0 0 2 2 2 0 SYF2 splicing factor Glyco_hydro_72 PF03198.14 EJS41800.1 - 4.7e-147 489.3 10.6 7e-147 488.7 10.6 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EJS41800.1 - 7.1e-05 22.4 0.3 0.00092 18.7 0.3 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EJS41800.1 - 0.0015 17.7 2.0 0.0038 16.4 2.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Nop14 PF04147.12 EJS41800.1 - 0.017 13.4 7.4 0.023 13.0 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family SOG2 PF10428.9 EJS41800.1 - 0.13 11.4 14.8 0.17 11.0 14.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein BUD22 PF09073.10 EJS41800.1 - 0.29 10.4 19.1 0.41 9.9 19.1 1.2 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 EJS41800.1 - 0.43 9.1 18.1 0.56 8.7 18.1 1.2 1 0 0 1 1 1 0 Macoilin family SDA1 PF05285.12 EJS41800.1 - 0.44 9.9 10.5 0.56 9.6 10.5 1.1 1 0 0 1 1 1 0 SDA1 SPX PF03105.19 EJS41800.1 - 0.58 10.0 17.8 0.88 9.4 17.8 1.2 1 0 0 1 1 1 0 SPX domain Striatin PF08232.12 EJS41800.1 - 1.1 9.9 3.2 1.9 9.0 3.2 1.4 1 0 0 1 1 1 0 Striatin family Apt1 PF10351.9 EJS41800.1 - 1.8 7.4 24.1 2.6 6.8 24.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 EJS41800.1 - 1.9 6.7 10.6 2.9 6.1 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.13 EJS41800.1 - 4.1 5.7 9.7 5.5 5.2 9.7 1.1 1 0 0 1 1 1 0 Menin SpoIIIAH PF12685.7 EJS41800.1 - 4.3 7.1 15.3 6.8 6.5 15.3 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Tmemb_cc2 PF10267.9 EJS41800.1 - 5.6 6.0 10.0 7.8 5.5 10.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Hid1 PF12722.7 EJS41800.1 - 6.8 4.7 10.7 9.5 4.2 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 EJS41800.1 - 7.2 5.3 11.5 11 4.7 11.5 1.2 1 0 0 1 1 1 0 Presenilin LETM1 PF07766.13 EJS41801.1 - 2.6e-99 331.9 6.3 2.6e-99 331.9 6.3 1.5 2 0 0 2 2 2 1 LETM1-like protein TOM13 PF08219.11 EJS41802.1 - 2.6e-24 85.0 0.0 3.1e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 HRXXH PF13933.6 EJS41803.1 - 3.1e-84 282.4 0.6 3.8e-84 282.1 0.6 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 EJS41803.1 - 3.6e-07 30.8 0.3 9.1e-07 29.5 0.1 1.8 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase 3Beta_HSD PF01073.19 EJS41804.1 - 8.6e-14 51.2 0.1 1.1e-13 50.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EJS41804.1 - 6.2e-13 48.8 0.0 1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJS41804.1 - 4.2e-06 26.8 0.0 7.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EJS41804.1 - 4.8e-05 22.9 0.0 9.4e-05 22.0 0.0 1.7 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EJS41804.1 - 7.2e-05 22.1 0.0 0.0012 18.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EJS41804.1 - 0.00065 18.9 0.1 0.0019 17.4 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EJS41804.1 - 0.0013 18.2 0.0 0.0038 16.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EJS41804.1 - 0.046 12.8 0.0 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 EJS41804.1 - 0.049 13.2 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family RbpA PF13397.6 EJS41804.1 - 0.11 13.1 0.1 0.25 12.0 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase-binding protein Spt20 PF12090.8 EJS41805.1 - 3e-70 236.4 10.7 3e-70 236.4 10.7 3.5 3 0 0 3 3 3 2 Spt20 family DUF4598 PF15370.6 EJS41805.1 - 0.022 15.2 0.0 0.022 15.2 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4598) RskA PF10099.9 EJS41805.1 - 0.45 10.8 4.7 0.11 12.8 1.1 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PEX11 PF05648.14 EJS41806.1 - 4e-65 219.4 4.8 4.5e-65 219.2 4.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sld5 PF05916.11 EJS41807.1 - 5.2e-21 75.2 0.1 6.6e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 GINS complex protein RRM_1 PF00076.22 EJS41808.1 - 0.00054 19.7 3.2 0.0013 18.5 1.7 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VASt PF16016.5 EJS41808.1 - 0.012 16.0 0.8 0.037 14.4 0.8 1.8 1 0 0 1 1 1 0 VAD1 Analog of StAR-related lipid transfer domain DMRL_synthase PF00885.19 EJS41809.1 - 1.4e-50 170.8 0.2 1.6e-50 170.6 0.2 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase KH_6 PF15985.5 EJS41810.1 - 2.7e-14 53.2 0.0 4.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 EJS41810.1 - 1.4e-13 50.6 0.1 2.4e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain E1_UFD PF09358.10 EJS41810.1 - 0.0018 18.9 0.0 0.0034 18.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fold domain LCM PF04072.14 EJS41811.1 - 1.1e-32 113.5 0.0 2e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 EJS41811.1 - 1e-16 60.6 5.3 1e-09 38.2 0.0 5.6 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EJS41811.1 - 1.2e-11 44.5 5.3 0.0029 17.8 0.0 6.5 6 1 1 7 7 7 4 Kelch motif Kelch_5 PF13854.6 EJS41811.1 - 3.2e-09 36.6 0.2 0.32 11.0 0.0 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 EJS41811.1 - 5.7e-09 35.4 4.3 0.004 16.7 0.0 6.3 6 0 0 6 6 6 1 Kelch motif Kelch_2 PF07646.15 EJS41811.1 - 2.6e-08 33.5 1.3 0.038 14.0 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EJS41811.1 - 2.9e-07 30.6 0.9 0.45 10.9 0.0 4.4 5 0 0 5 5 5 3 Galactose oxidase, central domain PGM1_C PF18105.1 EJS41811.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 PGM1 C-terminal domain Aminotran_3 PF00202.21 EJS41812.1 - 1.3e-136 455.5 0.1 1.6e-136 455.2 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PucR PF07905.11 EJS41812.1 - 0.032 14.5 0.1 2.7 8.3 0.0 3.0 3 0 0 3 3 3 0 Purine catabolism regulatory protein-like family Aminotran_5 PF00266.19 EJS41812.1 - 0.042 12.8 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V IF4E PF01652.18 EJS41813.1 - 8.4e-54 181.7 0.2 1e-53 181.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MFS_1 PF07690.16 EJS41814.1 - 1.3e-23 83.6 39.1 1.2e-20 73.8 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 6PF2K PF01591.18 EJS41815.1 - 1e-77 260.4 3.9 1.5e-77 259.9 3.9 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.6 EJS41815.1 - 0.00015 22.3 0.0 0.00041 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EJS41815.1 - 0.00061 19.3 0.0 0.00099 18.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EJS41815.1 - 0.0011 19.1 0.0 0.0023 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain C5-epim_C PF06662.13 EJS41815.1 - 0.0026 17.3 0.0 0.0092 15.5 0.0 2.0 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Ploopntkinase3 PF18751.1 EJS41815.1 - 0.021 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 zf-rbx1 PF12678.7 EJS41816.1 - 1.5e-23 82.8 13.3 2.6e-23 82.1 13.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EJS41816.1 - 7.2e-17 61.2 10.1 1e-16 60.7 10.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EJS41816.1 - 1.2e-05 25.5 14.1 0.00059 20.1 14.1 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJS41816.1 - 0.00029 20.6 1.7 0.00029 20.6 1.7 2.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJS41816.1 - 0.0023 17.7 11.9 0.023 14.5 11.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EJS41816.1 - 0.0047 16.6 1.3 0.0047 16.6 1.3 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 EJS41816.1 - 0.15 12.3 6.7 0.28 11.4 0.4 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EJS41816.1 - 1 9.3 10.8 3 7.8 4.5 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EJS41816.1 - 1.4 8.6 14.7 64 3.3 14.7 2.4 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EJS41816.1 - 1.8 8.8 9.9 10 6.4 10.2 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 EJS41816.1 - 2.1 8.5 9.5 8 6.6 9.5 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EJS41816.1 - 2.7 8.0 10.0 14 5.7 10.0 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 EJS41816.1 - 4.7 7.6 11.5 43 4.5 11.5 2.3 1 1 0 1 1 1 0 RING-like domain Glyco_hydro_72 PF03198.14 EJS41817.1 - 8.7e-141 468.7 3.9 1.1e-140 468.4 3.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EJS41817.1 - 0.00017 21.1 0.4 0.0019 17.7 0.1 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) KGK PF08872.10 EJS41817.1 - 0.27 11.7 4.5 0.82 10.2 4.5 1.8 1 1 0 1 1 1 0 KGK domain CorA PF01544.18 EJS41819.1 - 3.9e-39 134.7 1.5 8.4e-23 81.1 0.0 2.2 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein UPF0220 PF05255.11 EJS41820.1 - 2.9e-71 238.4 1.6 3.4e-71 238.2 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pkinase PF00069.25 EJS41821.1 - 1.7e-52 178.4 0.0 2.4e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41821.1 - 3e-24 85.7 0.0 4.1e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS41821.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJS41821.1 - 0.0029 17.0 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJS41821.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNaseH_C PF09293.10 EJS41821.1 - 0.049 14.0 0.5 2 8.8 0.0 2.5 2 0 0 2 2 2 0 T4 RNase H, C terminal TRM13 PF05206.14 EJS41822.1 - 2.3e-78 263.4 1.7 3.4e-78 262.8 1.7 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 EJS41822.1 - 8.8e-13 47.8 3.5 2e-12 46.6 3.5 1.6 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 EJS41822.1 - 2.1e-10 40.3 1.1 4.8e-10 39.1 1.1 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger UPF0020 PF01170.18 EJS41823.1 - 2.3e-11 43.7 0.0 4.1e-10 39.7 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EJS41823.1 - 0.0061 16.3 0.0 0.25 11.0 0.0 2.4 2 1 0 2 2 2 1 DNA methylase MethyltransfD12 PF02086.15 EJS41823.1 - 0.011 15.4 2.2 1.7 8.2 0.0 3.2 2 1 0 3 3 3 0 D12 class N6 adenine-specific DNA methyltransferase N6_Mtase PF02384.16 EJS41823.1 - 0.045 13.0 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 N-6 DNA Methylase RRM_1 PF00076.22 EJS41824.1 - 5.6e-34 115.8 0.2 7.4e-17 60.9 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJS41824.1 - 4.9e-13 49.0 1.3 4.4e-07 29.9 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif OB_RNB PF08206.11 EJS41824.1 - 0.029 14.0 0.2 8.3 6.2 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain Glyco_H_20C_C PF18088.1 EJS41824.1 - 0.07 13.0 4.2 0.13 12.1 4.2 1.3 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain CCDC84 PF14968.6 EJS41824.1 - 1.1 8.8 23.2 0.13 11.9 11.1 2.1 2 0 0 2 2 2 0 Coiled coil protein 84 CDK2AP PF09806.9 EJS41824.1 - 2.3 8.2 24.3 1.2 9.1 6.5 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Nramp PF01566.18 EJS41825.1 - 3e-90 302.8 20.7 1.1e-89 300.9 17.4 2.3 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein DUF5488 PF17590.2 EJS41825.1 - 0.27 11.0 2.7 0.29 10.9 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5488) MFS_1 PF07690.16 EJS41826.1 - 4.1e-27 95.0 35.6 4.1e-27 95.0 35.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GCR1_C PF12550.8 EJS41827.1 - 3.4e-23 81.8 0.5 7.6e-23 80.6 0.5 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TRAF_BIRC3_bd PF16673.5 EJS41827.1 - 0.11 12.3 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain NTP_transf_2 PF01909.23 EJS41828.1 - 8.6e-19 67.6 1.1 3.5e-18 65.7 0.0 2.6 3 0 0 3 3 3 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EJS41828.1 - 4e-14 52.6 0.2 2.1e-13 50.3 0.0 2.4 2 1 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 EJS41828.1 - 0.0011 19.0 0.6 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 EJS41828.1 - 0.0039 17.4 0.0 0.0099 16.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm Pkinase PF00069.25 EJS41829.1 - 2.6e-60 204.0 0.5 1.5e-59 201.6 0.2 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41829.1 - 1.5e-50 171.9 0.1 2.4e-50 171.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EJS41829.1 - 2.7e-23 82.1 1.2 4.8e-23 81.3 0.1 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.29 EJS41829.1 - 5.2e-12 46.2 0.3 1.2e-11 45.0 0.3 1.7 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 EJS41829.1 - 3.4e-06 26.1 0.6 1.9e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase PH_11 PF15413.6 EJS41829.1 - 2.6e-05 24.6 0.3 2.6e-05 24.6 0.3 2.4 3 1 0 3 3 3 1 Pleckstrin homology domain Kinase-like PF14531.6 EJS41829.1 - 5e-05 22.8 0.0 9.1e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Get5_bdg PF16843.5 EJS41830.1 - 8.7e-23 79.6 0.9 8.7e-23 79.6 0.9 2.2 3 0 0 3 3 3 1 Binding domain to Get4 on Get5, Golgi to ER traffic protein Get5_C PF18514.1 EJS41830.1 - 5.8e-21 73.9 2.9 1.9e-20 72.3 0.4 2.5 2 0 0 2 2 2 1 Get5 C-terminal domain ubiquitin PF00240.23 EJS41830.1 - 2.1e-13 49.8 0.3 4.4e-13 48.8 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 EJS41830.1 - 2.7e-05 24.2 0.3 6.2e-05 23.1 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 EJS41830.1 - 0.0057 16.5 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EJS41830.1 - 0.08 13.5 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Erf4 PF10256.9 EJS41831.1 - 8.7e-22 77.4 0.0 1.2e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Apolipoprotein PF01442.18 EJS41832.1 - 0.011 15.7 18.0 0.035 14.0 18.0 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EJS41832.1 - 0.014 16.0 13.3 0.031 14.9 12.5 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) GLYCAM-1 PF05242.11 EJS41832.1 - 0.23 11.6 12.1 2.1 8.5 12.1 2.0 1 1 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) GldM_N PF12081.8 EJS41832.1 - 0.28 11.2 16.0 0.38 10.8 16.0 1.2 1 0 0 1 1 1 0 GldM N-terminal domain Spc7 PF08317.11 EJS41832.1 - 0.35 9.7 19.9 0.39 9.6 19.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EJS41832.1 - 0.56 9.7 11.3 0.61 9.6 11.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit GPHR_N PF12537.8 EJS41832.1 - 0.73 10.0 3.7 0.23 11.5 0.8 1.7 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Prominin PF05478.11 EJS41832.1 - 0.9 7.4 6.8 1 7.2 6.8 1.2 1 0 0 1 1 1 0 Prominin TMPIT PF07851.13 EJS41832.1 - 0.94 8.7 13.0 1.1 8.4 13.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein ATP11 PF06644.11 EJS41832.1 - 1.2 8.9 16.8 0.96 9.2 16.1 1.3 1 1 0 1 1 1 0 ATP11 protein Ycf1 PF05758.12 EJS41832.1 - 1.9 6.2 12.2 2.1 6.1 12.2 1.0 1 0 0 1 1 1 0 Ycf1 Mitofilin PF09731.9 EJS41832.1 - 2 7.2 23.2 2.3 7.0 23.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3584 PF12128.8 EJS41832.1 - 2.7 5.4 19.2 3 5.2 19.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1043 PF06295.12 EJS41832.1 - 4.4 7.3 15.0 5.5 7.0 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Red1 PF07964.11 EJS41832.1 - 6.1 5.0 20.6 7.2 4.7 20.6 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Borrelia_P83 PF05262.11 EJS41832.1 - 7.5 4.9 23.2 8.9 4.7 23.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 EJS41832.1 - 8.8 6.1 18.6 10 5.8 18.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP70 PF00012.20 EJS41832.1 - 10 4.2 17.5 11 4.0 17.5 1.1 1 0 0 1 1 1 0 Hsp70 protein WSC PF01822.19 EJS41833.1 - 1.7e-09 37.7 11.1 1.7e-09 37.7 11.1 3.2 2 1 0 2 2 2 1 WSC domain Syndecan PF01034.20 EJS41833.1 - 3.8e-06 26.7 0.0 9.9e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.10 EJS41833.1 - 2e-05 23.9 0.9 2e-05 23.9 0.9 2.9 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.18 EJS41833.1 - 0.00069 19.8 0.1 0.00069 19.8 0.1 5.0 2 1 1 3 3 3 1 Glycophorin A Podoplanin PF05808.11 EJS41833.1 - 0.01 15.9 10.5 0.01 15.9 10.5 3.4 1 1 1 2 2 2 0 Podoplanin EphA2_TM PF14575.6 EJS41833.1 - 0.013 16.4 0.2 0.066 14.1 0.0 2.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 EJS41833.1 - 0.026 14.3 0.1 0.026 14.3 0.1 2.1 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Ni_hydr_CYTB PF01292.20 EJS41833.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4064 PF13273.6 EJS41833.1 - 0.24 11.7 0.0 0.24 11.7 0.0 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Sugar_tr PF00083.24 EJS41835.1 - 4.6e-138 460.9 29.2 5.6e-138 460.6 29.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS41835.1 - 2.3e-28 99.1 33.8 1e-27 97.0 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EJS41835.1 - 3.8e-06 25.6 2.2 3.8e-06 25.6 2.2 2.0 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EJS41835.1 - 0.0017 16.9 0.4 0.0017 16.9 0.4 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector DUF4637 PF15470.6 EJS41835.1 - 0.02 14.6 0.1 0.033 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2530 PF10745.9 EJS41835.1 - 6.3 7.1 6.5 1.5 9.1 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) PTS_2-RNA PF01885.16 EJS41836.1 - 1.4e-57 194.7 0.5 1.7e-57 194.4 0.5 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PARP PF00644.20 EJS41836.1 - 0.047 13.3 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain HlyIII PF03006.20 EJS41837.1 - 1.7e-14 54.1 19.7 2.3e-14 53.7 19.7 1.2 1 0 0 1 1 1 1 Haemolysin-III related Methyltransf_23 PF13489.6 EJS41838.1 - 2.2e-22 79.7 0.0 3.1e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJS41838.1 - 7.3e-13 49.0 0.0 1.4e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS41838.1 - 9.8e-13 48.6 0.0 2.7e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJS41838.1 - 1e-10 42.2 0.0 2.8e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJS41838.1 - 1.3e-09 38.1 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EJS41838.1 - 2.1e-07 30.6 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 EJS41838.1 - 2.1e-06 27.5 0.0 3.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EJS41838.1 - 4e-06 26.5 0.0 6.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EJS41838.1 - 8e-06 25.4 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EJS41838.1 - 0.00049 20.1 0.0 0.00092 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EJS41838.1 - 0.00055 19.6 0.1 0.0017 18.0 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 EJS41838.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 EJS41838.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.18 EJS41838.1 - 0.029 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EJS41838.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UvrD-helicase PF00580.21 EJS41839.1 - 1.1e-38 133.5 5.5 1.3e-19 70.8 3.3 2.9 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EJS41839.1 - 3.1e-29 102.2 0.1 7.7e-29 100.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 EJS41839.1 - 3e-26 92.6 0.1 2.9e-25 89.4 0.0 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EJS41839.1 - 7.2e-14 51.3 0.0 1.4e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EJS41839.1 - 1.8e-11 44.3 0.2 9.6e-05 22.2 0.1 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EJS41839.1 - 3.6e-08 33.5 0.1 1.5e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EJS41839.1 - 0.0068 16.1 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EJS41839.1 - 0.048 13.9 0.0 18 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EJS41839.1 - 0.072 12.3 4.6 4.9 6.3 0.0 3.5 4 1 1 5 5 5 0 Uncharacterized conserved protein (DUF2075) RWD PF05773.22 EJS41839.1 - 0.1 12.9 0.5 0.39 11.0 0.5 2.1 1 0 0 1 1 1 0 RWD domain Muted PF14942.6 EJS41839.1 - 0.53 10.6 5.7 0.24 11.8 0.6 2.5 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Rep_fac_C PF08542.11 EJS41840.1 - 5.6e-21 74.7 0.6 1.9e-20 73.0 0.1 2.1 2 1 1 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EJS41840.1 - 2e-14 53.7 0.1 1.1e-10 41.6 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EJS41840.1 - 5.2e-13 49.6 0.0 1e-12 48.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJS41840.1 - 9e-08 32.7 0.0 3.7e-05 24.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EJS41840.1 - 3e-07 30.5 0.0 3e-06 27.3 0.0 2.2 1 1 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 EJS41840.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EJS41840.1 - 1.3e-05 25.5 0.3 0.012 15.9 0.1 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 EJS41840.1 - 3.5e-05 23.6 0.0 0.00011 21.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EJS41840.1 - 0.0001 22.1 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EJS41840.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase TniB PF05621.11 EJS41840.1 - 0.00016 21.1 0.2 0.55 9.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein Mg_chelatase PF01078.21 EJS41840.1 - 0.0017 17.8 0.1 0.026 13.9 0.1 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 EJS41840.1 - 0.0028 17.6 0.1 0.029 14.3 0.0 2.2 1 1 0 2 2 2 1 NTPase AAA_assoc_2 PF16193.5 EJS41840.1 - 0.0058 16.9 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_24 PF13479.6 EJS41840.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EJS41840.1 - 0.018 14.0 0.0 0.12 11.3 0.0 2.2 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DNA_pol3_delta PF06144.13 EJS41840.1 - 0.02 14.7 0.6 0.034 13.9 0.6 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 EJS41840.1 - 0.028 14.8 0.6 0.37 11.1 0.1 2.4 2 1 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EJS41840.1 - 0.034 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.22 EJS41840.1 - 0.034 13.3 0.0 0.063 12.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 EJS41840.1 - 0.045 13.5 0.3 0.058 13.2 0.3 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EJS41840.1 - 0.094 12.4 0.1 0.27 10.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EJS41840.1 - 0.11 12.4 0.1 0.41 10.5 0.1 1.9 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EJS41840.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EJS41840.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.7 1 1 0 1 1 1 0 RNA helicase PQ-loop PF04193.14 EJS41841.1 - 6.9e-41 137.8 14.5 9.4e-21 73.3 2.9 2.7 2 0 0 2 2 2 2 PQ loop repeat UPF0242 PF06785.11 EJS41842.1 - 0.0017 18.5 1.5 0.0017 18.5 1.5 3.4 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus BLOC1_2 PF10046.9 EJS41842.1 - 4.9 7.5 28.7 9.1 6.7 4.2 5.0 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 EJS41842.1 - 5.3 7.7 7.3 16 6.2 0.0 4.1 2 1 3 5 5 5 0 SlyX MutS_V PF00488.21 EJS41843.1 - 2.8e-85 285.1 0.2 6.6e-85 283.9 0.2 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EJS41843.1 - 3.6e-33 115.4 3.9 3.7e-33 115.3 0.2 2.4 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EJS41843.1 - 3.3e-25 88.9 2.3 3.6e-25 88.8 0.2 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EJS41843.1 - 1.8e-19 69.9 0.8 6.3e-19 68.1 0.8 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 EJS41843.1 - 5.7e-10 39.4 0.1 3.5e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 MutS domain I DNA_ligase_A_N PF04675.14 EJS41843.1 - 0.058 13.7 1.0 0.25 11.6 1.0 2.3 1 1 0 1 1 1 0 DNA ligase N terminus AAA_27 PF13514.6 EJS41843.1 - 0.081 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DASH_Duo1 PF08651.10 EJS41843.1 - 0.2 11.4 2.5 0.73 9.6 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 Fungal_trans PF04082.18 EJS41844.1 - 1.8e-39 135.4 4.4 1.8e-39 135.4 4.4 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS41844.1 - 6.6e-09 35.8 13.3 1.3e-08 34.8 13.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2935 PF11155.8 EJS41844.1 - 0.17 12.2 2.0 0.91 9.9 0.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Thioredoxin PF00085.20 EJS41845.1 - 2.9e-11 43.3 0.3 7.5e-11 41.9 0.2 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EJS41845.1 - 0.021 15.2 0.3 0.07 13.5 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like DUF3337 PF11816.8 EJS41846.1 - 2.4e-31 108.9 1.6 6.4e-30 104.3 1.6 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EJS41846.1 - 0.00013 22.7 1.4 5.3 8.1 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat RAWUL PF16207.5 EJS41846.1 - 0.004 17.8 0.3 0.072 13.8 0.0 2.7 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like ADH_N PF08240.12 EJS41847.1 - 2.9e-29 101.1 0.4 8.1e-29 99.7 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJS41847.1 - 3.5e-25 88.5 2.0 5.5e-25 87.8 2.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJS41847.1 - 1.5e-05 26.1 0.1 2.5e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ATG19_autophagy PF12744.7 EJS41848.1 - 3.5e-94 314.6 0.8 6e-94 313.9 0.4 1.6 2 0 0 2 2 2 1 Autophagy protein Atg19, Atg8-binding Sugarporin_N PF11471.8 EJS41848.1 - 0.023 14.6 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension CRISPR_Cse1 PF09481.10 EJS41848.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) RasGAP PF00616.19 EJS41849.1 - 7.7e-27 94.4 8.7 1.6e-18 67.2 0.4 4.2 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase RNase_T PF00929.24 EJS41850.1 - 4e-17 63.2 0.0 6.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EJS41850.1 - 0.011 15.4 0.0 0.044 13.5 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease ATP19 PF11022.8 EJS41851.1 - 6.1e-23 81.0 0.0 6.9e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K Brix PF04427.18 EJS41852.1 - 2.3e-41 142.0 0.1 3.4e-41 141.5 0.1 1.2 1 0 0 1 1 1 1 Brix domain NatB_MDM20 PF09797.9 EJS41853.1 - 2.8e-52 178.0 13.5 6.9e-52 176.6 13.5 1.7 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit GP40 PF11025.8 EJS41853.1 - 0.19 11.5 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium DUF5600 PF18150.1 EJS41853.1 - 7.7 7.1 7.0 5.5 7.6 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF5600) ABC_tran PF00005.27 EJS41854.1 - 6.5e-51 172.4 0.5 2.3e-24 86.5 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EJS41854.1 - 1e-40 139.4 34.3 4.5e-25 88.3 14.1 2.5 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 EJS41854.1 - 4.3e-12 46.5 9.8 0.00015 21.7 0.1 4.4 2 2 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EJS41854.1 - 5.2e-10 39.5 3.0 8.8e-05 22.5 0.1 2.8 2 1 1 3 3 3 2 RsgA GTPase SMC_N PF02463.19 EJS41854.1 - 2.3e-09 37.0 3.6 6.3e-06 25.8 0.1 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EJS41854.1 - 3.6e-07 30.5 0.1 0.0055 17.0 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.6 EJS41854.1 - 5.3e-07 30.2 0.0 0.024 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EJS41854.1 - 1.8e-06 27.6 2.2 0.061 13.1 0.0 3.1 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EJS41854.1 - 3.1e-05 23.9 0.0 0.03 14.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 EJS41854.1 - 6.9e-05 23.4 0.1 0.52 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EJS41854.1 - 0.00012 22.6 7.7 0.075 13.5 0.1 4.0 3 1 1 4 4 3 2 AAA domain AAA_28 PF13521.6 EJS41854.1 - 0.00013 22.2 0.2 0.028 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EJS41854.1 - 0.00014 21.5 0.1 0.022 14.3 0.0 3.2 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 EJS41854.1 - 0.00057 20.2 1.3 1.8 9.0 0.0 3.6 3 0 0 3 3 3 1 RNA helicase MMR_HSR1 PF01926.23 EJS41854.1 - 0.00088 19.3 3.6 0.12 12.4 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 EJS41854.1 - 0.001 18.2 1.1 0.13 11.3 0.3 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 EJS41854.1 - 0.0014 18.4 0.4 0.61 9.8 0.2 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 EJS41854.1 - 0.0026 17.0 0.1 1.2 8.3 0.0 2.4 2 0 0 2 2 2 1 KAP family P-loop domain ATPase_2 PF01637.18 EJS41854.1 - 0.0041 17.1 0.0 1 9.2 0.0 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 EJS41854.1 - 0.0048 17.3 0.1 4.7 7.6 0.0 3.5 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EJS41854.1 - 0.0054 16.7 0.3 1.6 8.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EJS41854.1 - 0.0066 16.9 0.1 1.7 9.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EJS41854.1 - 0.008 16.1 0.3 13 5.6 0.1 3.3 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 EJS41854.1 - 0.0081 15.4 0.6 0.82 8.8 0.1 2.6 2 0 0 2 2 2 1 NB-ARC domain Cytidylate_kin PF02224.18 EJS41854.1 - 0.014 15.2 1.8 0.44 10.2 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase AAA_24 PF13479.6 EJS41854.1 - 0.017 14.9 1.3 4.9 6.8 0.5 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EJS41854.1 - 0.025 14.9 0.2 0.51 10.7 0.2 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 EJS41854.1 - 0.026 14.0 1.6 0.19 11.2 0.4 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Adeno_IVa2 PF02456.15 EJS41854.1 - 0.033 13.0 0.4 0.066 12.0 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.6 EJS41854.1 - 0.037 14.0 0.0 7.3 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EJS41854.1 - 0.042 14.1 0.7 22 5.4 0.0 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EJS41854.1 - 0.062 13.5 0.0 5.8 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EJS41854.1 - 0.064 12.6 1.6 0.76 9.1 0.4 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 EJS41854.1 - 0.085 12.4 2.6 3.4 7.2 0.9 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 EJS41854.1 - 0.088 12.5 2.3 5.9 6.6 0.2 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 EJS41854.1 - 0.12 12.5 8.3 0.73 9.9 0.0 3.4 4 1 0 4 4 3 0 Helicase HerA, central domain Zeta_toxin PF06414.12 EJS41854.1 - 0.24 10.6 0.8 5.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.6 EJS41854.1 - 0.64 8.6 3.9 6 5.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.17 EJS41854.1 - 0.84 9.4 3.2 14 5.3 0.8 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EJS41854.1 - 1.8 8.0 5.1 8.2 5.9 0.1 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EJS41854.1 - 1.8 8.6 6.6 5.8 6.9 0.9 2.8 2 0 0 2 2 2 0 Dynamin family PCI PF01399.27 EJS41856.1 - 1.1e-18 67.7 0.3 4.9e-18 65.6 0.1 2.3 2 0 0 2 2 2 1 PCI domain HTH_IclR PF09339.10 EJS41856.1 - 0.11 12.3 0.0 17 5.3 0.0 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain Nuf2 PF03800.14 EJS41857.1 - 2e-44 151.1 2.3 2e-44 151.1 2.3 2.0 2 0 0 2 2 2 1 Nuf2 family PspB PF06667.12 EJS41857.1 - 0.79 9.8 4.7 12 6.1 0.2 2.9 2 0 0 2 2 2 0 Phage shock protein B HLH PF00010.26 EJS41858.1 - 4.6e-17 61.7 0.0 6.3e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MbeD_MobD PF04899.12 EJS41858.1 - 0.096 12.8 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 MbeD/MobD like Exo_endo_phos PF03372.23 EJS41859.1 - 2.3e-10 40.4 0.0 3.5e-10 39.8 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Inositol_P PF00459.25 EJS41860.1 - 3.5e-66 223.5 0.1 8.6e-65 218.9 0.1 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family Adap_comp_sub PF00928.21 EJS41861.1 - 6.4e-78 261.8 1.0 6.4e-78 261.8 1.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EJS41861.1 - 0.0007 19.5 0.1 0.0025 17.8 0.0 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain DUF5484 PF17583.2 EJS41861.1 - 0.071 12.8 0.2 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5484) Pribosyl_synth PF14572.6 EJS41862.1 - 7.2e-42 143.5 1.5 5.3e-41 140.7 1.5 2.1 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EJS41862.1 - 8.1e-34 116.1 0.0 2.2e-33 114.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EJS41862.1 - 3.8e-13 49.2 0.4 1.9e-07 30.7 0.2 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.6 EJS41862.1 - 0.11 11.9 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase NAD_Gly3P_dh_N PF01210.23 EJS41863.1 - 5e-53 179.3 0.0 7.6e-53 178.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EJS41863.1 - 9.8e-41 139.4 0.2 1.5e-40 138.7 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EJS41863.1 - 0.034 14.7 0.1 0.86 10.2 0.1 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EJS41863.1 - 0.12 12.2 0.1 4.9 7.0 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Arginosuc_synth PF00764.19 EJS41864.1 - 1.8e-166 554.2 0.0 2.1e-166 554.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EJS41864.1 - 3.4e-05 23.4 0.0 8.6e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EJS41864.1 - 0.00087 18.2 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Pyr_redox_2 PF07992.14 EJS41865.1 - 1.8e-28 99.6 0.0 2.4e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJS41865.1 - 1.8e-17 63.6 0.0 6.7e-13 49.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJS41865.1 - 0.00025 21.1 0.2 0.45 10.5 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EJS41865.1 - 0.00078 19.1 0.6 0.017 14.8 0.8 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EJS41865.1 - 0.025 13.7 0.0 2.5 7.2 0.1 2.8 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EJS41865.1 - 0.12 12.4 0.2 0.61 10.1 0.1 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 EJS41865.1 - 0.15 10.9 1.0 0.73 8.6 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD-oxidase_C PF02913.19 EJS41866.1 - 2.4e-52 178.1 0.0 3.1e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EJS41866.1 - 4.5e-35 120.4 0.0 8.4e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Ribosom_S12_S23 PF00164.25 EJS41868.1 - 2.1e-33 114.3 1.0 2.7e-33 114.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S19 PF00203.21 EJS41869.1 - 2.6e-27 94.5 0.0 3.2e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Cation_efflux PF01545.21 EJS41870.1 - 0.047 13.4 13.4 0.14 11.9 13.4 1.7 1 1 0 1 1 1 0 Cation efflux family UbiA PF01040.18 EJS41871.1 - 1.4e-47 162.1 13.8 2.4e-47 161.3 13.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family MDD_C PF18376.1 EJS41872.1 - 3.9e-66 222.4 0.1 5.5e-66 221.9 0.1 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EJS41872.1 - 1.9e-09 37.6 1.6 6.7e-09 35.9 1.8 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain Trm112p PF03966.16 EJS41874.1 - 1.7e-21 76.6 0.0 2.1e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein CDC50 PF03381.15 EJS41875.1 - 1.3e-85 287.3 0.1 1.7e-85 286.9 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family BSMAP PF12280.8 EJS41875.1 - 0.084 13.1 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein Mso1_Sec1_bdg PF14475.6 EJS41876.1 - 3e-17 61.9 0.0 5.5e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Sacchrp_dh_C PF16653.5 EJS41877.1 - 8.6e-92 308.0 0.0 1.2e-91 307.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EJS41877.1 - 3.1e-24 85.7 0.2 4.4e-24 85.2 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EJS41877.1 - 2.9e-08 33.8 0.5 6.8e-08 32.6 0.2 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 EJS41877.1 - 3.4e-08 33.6 0.1 6.2e-08 32.8 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 EJS41877.1 - 0.02 15.6 0.2 0.037 14.7 0.2 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain IlvN PF07991.12 EJS41877.1 - 0.031 13.9 0.2 0.086 12.4 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Semialdhyde_dh PF01118.24 EJS41877.1 - 0.058 13.8 0.1 0.15 12.5 0.1 1.6 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EJS41877.1 - 0.059 12.4 0.1 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.21 EJS41877.1 - 0.13 11.6 0.2 0.23 10.7 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 EJS41877.1 - 0.13 11.8 0.2 0.2 11.2 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family adh_short_C2 PF13561.6 EJS41877.1 - 0.18 11.3 0.6 0.33 10.5 0.6 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NTF2 PF02136.20 EJS41878.1 - 2.9e-25 89.2 0.2 5.6e-25 88.2 0.2 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EJS41878.1 - 0.0028 17.4 0.1 0.0069 16.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF1 PF04857.20 EJS41879.1 - 3.8e-15 55.9 8.3 8.6e-10 38.3 0.0 3.1 2 1 1 3 3 3 2 CAF1 family ribonuclease Mob1_phocein PF03637.17 EJS41879.1 - 0.0065 16.5 0.3 0.016 15.2 0.2 1.7 2 0 0 2 2 2 1 Mob1/phocein family RRM_1 PF00076.22 EJS41880.1 - 0.0022 17.8 0.1 0.32 10.8 0.1 2.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trypan_PARP PF05887.11 EJS41880.1 - 0.3 11.1 7.3 0.68 9.9 7.3 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.12 EJS41880.1 - 3.1 7.5 19.5 0.71 9.7 10.5 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4637 PF15470.6 EJS41880.1 - 3.8 7.2 13.9 0.14 11.9 4.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) MFS_1 PF07690.16 EJS41881.1 - 5.3e-32 111.1 20.1 5.3e-32 111.1 20.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Aminotran_3 PF00202.21 EJS41882.1 - 3.7e-99 332.1 0.0 8.8e-99 330.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EJS41882.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Mannosyl_trans3 PF11051.8 EJS41883.1 - 5.1e-64 216.3 0.5 7.1e-64 215.8 0.5 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative XET_C PF06955.12 EJS41883.1 - 0.0083 15.9 1.6 0.029 14.2 1.6 1.9 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus DUF5562 PF17717.1 EJS41883.1 - 0.12 12.4 0.0 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5562) Glyco_hydro81C PF17652.1 EJS41884.1 - 4.9e-148 493.0 11.0 7.2e-148 492.5 11.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EJS41884.1 - 8.4e-96 320.9 11.5 8.4e-96 320.9 11.5 2.9 4 0 0 4 4 4 1 Glycosyl hydrolase family 81 N-terminal domain Aldose_epim PF01263.20 EJS41885.1 - 7e-77 258.7 0.9 7.9e-77 258.5 0.9 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Gpr1_Fun34_YaaH PF01184.19 EJS41886.1 - 2.7e-92 308.1 20.9 3.1e-92 307.9 20.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family RNA_pol_Rpc34 PF05158.12 EJS41887.1 - 4.5e-115 384.6 1.0 5.3e-115 384.4 1.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.20 EJS41887.1 - 0.0061 16.9 0.9 0.022 15.1 0.1 2.1 2 0 0 2 2 2 1 Transcriptional regulator CDC13_N PF16853.5 EJS41887.1 - 0.03 13.8 0.8 0.076 12.5 0.0 2.0 2 0 0 2 2 2 0 Cell division control protein 13 N-terminus HTH_36 PF13730.6 EJS41887.1 - 0.037 14.0 0.6 1.1 9.3 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain B-block_TFIIIC PF04182.12 EJS41887.1 - 0.041 14.0 2.5 2.1 8.6 0.1 2.5 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC RPA_C PF08784.11 EJS41887.1 - 0.11 13.2 0.6 0.65 10.7 0.0 2.4 2 1 1 3 3 3 0 Replication protein A C terminal TFIIE_alpha PF02002.17 EJS41887.1 - 0.13 12.1 1.5 2.5 8.0 0.1 2.7 3 0 0 3 3 3 0 TFIIE alpha subunit HTH_46 PF15977.5 EJS41887.1 - 0.15 12.1 0.7 0.43 10.6 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding Swm2 PF17083.5 EJS41888.1 - 3.4e-56 188.8 0.1 3.8e-56 188.7 0.1 1.0 1 0 0 1 1 1 1 Nucleolar protein Swm2 VHS PF00790.19 EJS41889.1 - 2.7e-41 140.7 0.1 6.3e-41 139.5 0.1 1.6 1 0 0 1 1 1 1 VHS domain FYVE PF01363.21 EJS41889.1 - 8e-19 67.6 3.3 1.9e-18 66.3 3.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EJS41889.1 - 0.0003 20.5 13.6 0.029 14.3 1.5 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 EJS41889.1 - 0.0061 16.8 2.4 0.0061 16.8 2.4 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger GAT PF03127.14 EJS41889.1 - 0.52 10.6 6.6 0.15 12.4 2.6 2.2 2 0 0 2 2 2 0 GAT domain zf-AN1 PF01428.16 EJS41889.1 - 1.3 9.3 13.9 0.068 13.3 8.3 1.8 2 0 0 2 2 2 0 AN1-like Zinc finger RAP80_UIM PF18282.1 EJS41889.1 - 2.8 7.8 6.4 0.21 11.4 0.3 2.3 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif Autophagy_N PF03986.13 EJS41890.1 - 2.7e-44 150.4 0.2 2.7e-44 150.4 0.2 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EJS41890.1 - 9.3e-14 51.8 0.0 2e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EJS41890.1 - 1e-13 50.5 2.8 1.9e-13 49.7 2.8 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal LCAT PF02450.15 EJS41891.1 - 7e-148 493.0 0.7 9.5e-148 492.5 0.2 1.4 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 EJS41891.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 EJS41891.1 - 0.049 14.2 0.0 0.093 13.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 EJS41891.1 - 0.096 12.2 0.0 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 EJS41891.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Whi5 PF08528.11 EJS41892.1 - 6.7e-10 38.4 2.7 1.2e-09 37.6 2.7 1.4 1 0 0 1 1 1 1 Whi5 like Med9 PF07544.13 EJS41893.1 - 2.9e-26 91.4 1.9 5.5e-26 90.5 1.9 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Wx5_PLAF3D7 PF09688.10 EJS41893.1 - 0.035 14.1 0.4 0.035 14.1 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) HA2 PF04408.23 EJS41894.1 - 3.2e-17 62.8 1.4 1.1e-16 61.0 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EJS41894.1 - 4.5e-15 55.9 0.1 2.6e-14 53.5 0.0 2.4 2 0 0 2 2 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EJS41894.1 - 7.8e-15 55.0 0.0 2.2e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EJS41894.1 - 6.5e-08 32.5 0.3 2.2e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EJS41894.1 - 0.0003 21.1 0.0 0.00076 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJS41894.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJS41894.1 - 0.0034 17.7 0.1 0.0079 16.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EJS41894.1 - 0.0075 16.3 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SSE PF00437.20 EJS41894.1 - 0.011 14.8 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 EJS41894.1 - 0.046 13.1 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 EJS41894.1 - 0.049 14.2 0.2 0.049 14.2 0.2 2.4 2 1 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 EJS41894.1 - 0.061 13.2 0.2 0.33 10.8 0.0 2.3 3 0 0 3 3 3 0 RsgA GTPase PhoH PF02562.16 EJS41894.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Microtub_bd PF16796.5 EJS41894.1 - 0.33 10.9 2.8 7.9 6.4 0.0 3.6 3 1 1 4 4 4 0 Microtubule binding AAA_14 PF13173.6 EJS41894.1 - 0.38 10.8 2.9 6.6 6.8 0.2 3.6 3 1 0 3 3 3 0 AAA domain PRK PF00485.18 EJS41895.1 - 9.1e-69 231.1 0.0 1.3e-68 230.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EJS41895.1 - 3.8e-33 114.7 0.0 5.7e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 EJS41895.1 - 8e-05 23.2 0.1 0.00049 20.7 0.0 2.3 2 1 2 4 4 4 1 AAA domain AAA_17 PF13207.6 EJS41895.1 - 0.0011 19.4 0.4 0.041 14.3 0.4 2.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EJS41895.1 - 0.006 15.9 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.12 EJS41895.1 - 0.015 15.1 0.0 0.049 13.5 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EJS41895.1 - 0.047 13.8 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Gp_dh_C PF02800.20 EJS41895.1 - 0.097 12.3 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Cytidylate_kin PF02224.18 EJS41895.1 - 1 9.1 3.0 4.4 7.0 0.0 2.4 3 0 0 3 3 3 0 Cytidylate kinase SPX PF03105.19 EJS41896.1 - 1.6e-38 133.6 28.5 1e-25 91.5 11.3 3.1 2 1 1 3 3 3 2 SPX domain Na_sulph_symp PF00939.19 EJS41896.1 - 1.3e-24 87.2 41.9 1.8e-24 86.7 41.9 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EJS41896.1 - 3.8e-23 82.1 69.8 8.3e-21 74.5 43.1 2.3 2 1 1 3 3 3 2 Citrate transporter DUF4667 PF15700.5 EJS41897.1 - 5.9e-47 160.8 20.3 9e-46 156.9 20.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4667) RNA_pol_Rpo13 PF12136.8 EJS41897.1 - 0.015 15.1 1.2 0.024 14.5 1.2 1.3 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain DUF4698 PF15769.5 EJS41897.1 - 1.2 8.1 7.2 0.29 10.2 4.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4698) ACC_central PF08326.12 EJS41898.1 - 3.2e-263 875.3 0.0 4e-263 875.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EJS41898.1 - 3.6e-190 632.8 0.0 4.9e-190 632.4 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EJS41898.1 - 1.3e-50 171.9 0.0 2.6e-50 170.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EJS41898.1 - 9.6e-30 103.4 0.1 2e-29 102.3 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EJS41898.1 - 4.1e-21 75.1 0.0 1.5e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EJS41898.1 - 6.7e-18 64.3 0.3 1.7e-17 63.0 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EJS41898.1 - 0.0032 17.6 0.0 0.022 14.8 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EJS41898.1 - 0.0089 15.6 0.0 0.032 13.8 0.0 1.9 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EJS41898.1 - 0.028 14.2 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon HIG_1_N PF04588.13 EJS41899.1 - 3.7e-05 23.9 0.1 7.5e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MBOAT PF03062.19 EJS41900.1 - 1.5e-115 386.2 36.9 2e-115 385.9 36.9 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EJS41900.1 - 0.00034 20.8 5.3 0.001 19.3 5.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family EssA PF10661.9 EJS41900.1 - 0.16 11.8 1.1 13 5.6 0.5 2.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA DUF3439 PF11921.8 EJS41900.1 - 0.4 10.6 10.2 0.081 12.9 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FtsH_ext PF06480.15 EJS41900.1 - 0.67 10.3 3.7 14 6.1 0.2 2.5 2 0 0 2 2 2 0 FtsH Extracellular DUF1682 PF07946.14 EJS41901.1 - 7.8e-72 242.2 9.2 9.1e-72 242.0 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Smac_DIABLO PF09057.10 EJS41901.1 - 2.6 7.3 7.4 6.1 6.1 7.4 1.6 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Ribosomal_L9_N PF01281.19 EJS41902.1 - 0.0019 17.7 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DUF5383 PF17355.2 EJS41902.1 - 0.24 11.8 4.4 0.35 11.3 4.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) SWIB PF02201.18 EJS41903.1 - 0.0082 16.0 0.0 0.071 13.0 0.0 2.5 2 0 0 2 2 2 1 SWIB/MDM2 domain ANAPC4_WD40 PF12894.7 EJS41904.1 - 0.0051 17.1 0.0 1.1 9.6 0.0 2.8 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJS41904.1 - 0.12 13.3 3.4 4.7 8.2 0.0 4.3 5 1 0 5 5 5 0 WD domain, G-beta repeat Phos_pyr_kin PF08543.12 EJS41905.1 - 5.9e-10 38.9 0.0 7.6e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EJS41905.1 - 0.0017 17.7 0.0 0.0038 16.6 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Pro_isomerase PF00160.21 EJS41906.1 - 2.4e-12 47.4 0.0 4.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD cobW PF02492.19 EJS41907.1 - 5.2e-45 153.2 0.0 7.8e-45 152.6 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EJS41907.1 - 2.5e-07 30.5 0.0 4.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 EJS41907.1 - 0.0054 17.0 0.1 1.1 9.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EJS41907.1 - 0.0086 15.8 0.2 0.042 13.6 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJS41907.1 - 0.017 15.0 0.3 0.97 9.3 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 EJS41907.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.27 EJS41907.1 - 0.025 14.1 0.6 0.32 10.5 0.3 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DAP3 PF10236.9 EJS41907.1 - 0.03 13.5 0.1 0.052 12.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Bromo_TP_like PF17027.5 EJS41907.1 - 0.044 13.9 0.6 0.15 12.2 0.1 2.0 2 0 0 2 2 2 0 Histone-fold protein AAA_16 PF13191.6 EJS41907.1 - 0.044 14.1 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EJS41907.1 - 0.052 14.0 0.8 0.18 12.3 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EJS41907.1 - 0.08 13.5 0.0 0.25 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EJS41907.1 - 0.099 11.9 0.2 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 EJS41907.1 - 0.12 12.2 2.9 0.22 11.4 0.2 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Glyco_transf_22 PF03901.17 EJS41908.1 - 8.1e-35 120.8 24.2 1.1e-34 120.4 24.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family S1FA PF04689.13 EJS41908.1 - 0.14 12.3 1.4 0.56 10.4 0.0 2.6 1 1 1 2 2 2 0 DNA binding protein S1FA CPP1-like PF11833.8 EJS41908.1 - 8.6 6.0 6.7 2.3 7.8 0.9 2.4 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Pkinase PF00069.25 EJS41909.1 - 5.2e-63 212.9 0.0 1.7e-62 211.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41909.1 - 2e-34 119.1 0.1 1e-24 87.3 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EJS41909.1 - 3.2e-05 23.4 0.4 0.001 18.4 0.0 3.2 4 0 0 4 4 4 1 Kinase-like APH PF01636.23 EJS41909.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Metallophos PF00149.28 EJS41910.1 - 2.1e-34 119.8 0.7 3.6e-34 119.1 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ubiquitin PF00240.23 EJS41911.1 - 2.7e-07 30.2 0.3 3.1e-07 30.0 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EJS41911.1 - 0.0013 18.5 0.2 0.0014 18.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EJS41911.1 - 0.0067 16.9 0.3 0.044 14.2 0.3 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain CC2D2AN-C2 PF15625.6 EJS41911.1 - 0.082 12.6 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain Chorismate_bind PF00425.18 EJS41912.1 - 2.6e-66 223.8 0.0 3.6e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EJS41912.1 - 2.9e-30 105.5 0.0 4.6e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EJS41912.1 - 6.1e-19 68.6 0.0 2.8e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EJS41912.1 - 3.4e-05 23.7 0.0 7.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 Pax7 PF12360.8 EJS41912.1 - 0.14 12.4 0.2 0.6 10.4 0.0 2.2 2 0 0 2 2 2 0 Paired box protein 7 Glucosamine_iso PF01182.20 EJS41913.1 - 5.9e-53 180.0 0.0 1.7e-52 178.6 0.0 1.6 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PurS PF02700.14 EJS41914.1 - 0.037 14.2 0.3 0.075 13.2 0.3 1.6 1 1 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase UPF0052 PF01933.18 EJS41915.1 - 2.7e-69 233.6 0.1 3.3e-69 233.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF3842 PF12953.7 EJS41915.1 - 0.029 14.8 0.2 0.06 13.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) HAD PF12710.7 EJS41916.1 - 1.3e-25 90.9 0.0 1.7e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EJS41916.1 - 1.6e-07 31.0 0.0 2.4e-07 30.4 0.0 1.3 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 EJS41916.1 - 4.4e-05 23.1 0.0 9.3e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EJS41916.1 - 0.0038 17.6 0.0 0.4 10.9 0.0 2.8 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EJS41916.1 - 0.022 14.9 0.4 1.2 9.2 0.3 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.12 EJS41916.1 - 0.047 14.0 0.0 0.96 9.8 0.0 2.6 2 1 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Iso_dh PF00180.20 EJS41917.1 - 8.4e-73 245.5 0.1 9.7e-73 245.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DnaJ_C PF01556.18 EJS41918.1 - 4.1e-37 127.5 0.1 5.3e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EJS41918.1 - 2e-22 79.1 0.5 3.5e-22 78.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 EJS41919.1 - 1.9e-42 142.4 18.2 1.3e-10 41.7 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS41919.1 - 9.4e-15 54.7 2.0 0.046 14.0 0.0 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJS41919.1 - 6.1e-11 41.7 10.9 0.0084 14.8 0.1 4.8 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EJS41919.1 - 2.8e-07 29.8 1.4 0.48 9.3 0.0 4.8 1 1 4 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EJS41919.1 - 1.6e-06 27.2 1.4 0.14 10.9 0.0 3.8 1 1 3 4 4 4 2 Nup133 N terminal like Hira PF07569.11 EJS41919.1 - 9.1e-05 22.3 0.6 0.66 9.7 0.0 4.4 3 1 2 5 5 5 1 TUP1-like enhancer of split Nbas_N PF15492.6 EJS41919.1 - 0.00064 19.1 0.6 1.3 8.3 0.2 3.0 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 EJS41919.1 - 0.0015 16.9 0.0 0.013 13.9 0.0 2.1 1 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 EJS41919.1 - 0.0022 16.6 0.0 0.058 11.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 EJS41919.1 - 0.003 16.6 2.9 0.0075 15.2 0.0 2.7 3 1 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Ribosomal_L27_C PF18471.1 EJS41920.1 - 5.3e-91 304.3 25.5 6.3e-91 304.1 25.5 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Ribosomal_L27 PF01016.19 EJS41920.1 - 2.1e-32 111.0 0.1 3.9e-32 110.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein Mito_carr PF00153.27 EJS41921.1 - 8.5e-51 169.9 6.1 1.3e-20 73.0 0.2 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EJS41921.1 - 0.044 12.9 1.7 0.78 8.8 1.7 2.6 1 1 0 1 1 1 0 Gammaproteobacterial serine protease Ribosomal_L30 PF00327.20 EJS41922.1 - 1.2e-10 41.0 1.0 1.2e-10 41.0 1.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e eRF1_2 PF03464.15 EJS41923.1 - 2.8e-31 108.6 0.2 5.2e-31 107.7 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EJS41923.1 - 3.5e-24 85.4 1.2 6.2e-24 84.7 0.1 2.0 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 EJS41923.1 - 2.4e-22 79.3 0.1 3.8e-22 78.7 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 SNF2_N PF00176.23 EJS41923.1 - 0.09 11.5 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain NdhM PF10664.9 EJS41923.1 - 0.44 10.8 2.5 1.2 9.5 0.1 2.8 3 1 1 4 4 4 0 Cyanobacterial and plastid NDH-1 subunit M Citrate_synt PF00285.21 EJS41924.1 - 1.2e-100 337.1 0.0 1.5e-100 336.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF2795 PF11387.8 EJS41924.1 - 0.72 10.1 2.7 1.2 9.4 0.1 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2795) DUF4293 PF14126.6 EJS41926.1 - 0.27 11.5 2.3 0.4 10.9 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) O-ag_pol_Wzy PF14296.6 EJS41926.1 - 1.4 7.4 5.5 0.99 8.0 0.1 2.1 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy Y_phosphatase2 PF03162.13 EJS41927.1 - 1.2e-67 226.6 0.3 1.9e-67 225.9 0.1 1.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EJS41927.1 - 5.7e-07 29.7 0.0 9.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EJS41927.1 - 0.0014 18.5 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EJS41927.1 - 0.0037 16.9 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Syntaxin_2 PF14523.6 EJS41927.1 - 0.072 13.5 0.2 0.15 12.4 0.2 1.5 1 0 0 1 1 1 0 Syntaxin-like protein TMEM192 PF14802.6 EJS41927.1 - 0.09 11.9 0.3 9.2 5.3 0.1 2.3 2 0 0 2 2 2 0 TMEM192 family Histone PF00125.24 EJS41928.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EJS41928.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EJS41928.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EJS41928.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EJS41928.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EJS41928.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EJS41929.1 - 2.7e-09 37.1 0.1 3.2e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EJS41929.1 - 5.5e-05 23.2 0.1 7.8e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EJS41929.1 - 0.00014 22.3 0.1 0.00016 22.1 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EJS41929.1 - 0.00021 21.5 0.1 0.00036 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EJS41929.1 - 0.00029 21.2 0.1 0.00039 20.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EJS41929.1 - 0.0089 16.1 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EJS41929.1 - 0.04 13.9 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 EJS41929.1 - 0.073 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Glyco_transf_15 PF01793.16 EJS41930.1 - 2.4e-90 303.1 14.9 6.7e-58 196.5 5.7 2.2 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Bac_surface_Ag PF01103.23 EJS41931.1 - 6.4e-49 167.2 0.6 8.7e-49 166.7 0.6 1.1 1 0 0 1 1 1 1 Surface antigen Cyclin_N PF00134.23 EJS41932.1 - 3.9e-17 62.2 0.6 3.9e-16 58.9 0.3 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EJS41932.1 - 0.00017 21.9 0.1 0.00047 20.5 0.1 1.9 1 1 0 1 1 1 1 Cyclin C-terminal domain DUF1242 PF06842.12 EJS41933.1 - 1.1e-15 57.1 0.2 1.6e-15 56.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Pkinase PF00069.25 EJS41934.1 - 7.2e-37 127.2 0.0 1.2e-36 126.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41934.1 - 6e-27 94.5 0.0 9e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS41934.1 - 0.0027 17.1 0.0 0.0056 16.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EJS41934.1 - 0.019 14.9 0.0 2 8.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family C2 PF00168.30 EJS41935.1 - 2.6e-55 185.1 8.7 1.5e-18 67.0 0.0 5.3 5 0 0 5 5 5 4 C2 domain SMP_LBD PF17047.5 EJS41935.1 - 0.0043 16.5 0.6 0.019 14.4 0.6 2.0 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Snapin_Pallidin PF14712.6 EJS41936.1 - 7.9e-09 35.8 0.5 9.7e-09 35.5 0.5 1.0 1 0 0 1 1 1 1 Snapin/Pallidin FlaC_arch PF05377.11 EJS41936.1 - 0.047 14.1 0.6 0.36 11.3 0.2 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YscO PF07321.12 EJS41936.1 - 0.071 13.1 0.1 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Type III secretion protein YscO EF-hand_4 PF12763.7 EJS41937.1 - 3.8e-52 174.6 3.9 8.1e-49 163.9 2.3 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 EJS41937.1 - 2.2e-29 103.1 12.9 5.2e-15 56.2 0.2 2.3 1 1 1 2 2 2 2 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.32 EJS41937.1 - 0.0012 18.2 3.3 0.017 14.6 1.7 2.6 2 0 0 2 2 2 1 EF hand HMMR_N PF15905.5 EJS41937.1 - 0.0022 17.5 8.8 0.0033 17.0 8.8 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Erp_C PF06780.11 EJS41937.1 - 0.11 12.5 11.6 1.3 9.0 11.9 2.3 1 1 0 1 1 1 0 Erp protein C-terminus DUF2335 PF10097.9 EJS41937.1 - 0.12 12.4 0.1 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) CorA PF01544.18 EJS41937.1 - 0.17 11.2 7.4 2.8 7.2 7.5 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein EF-hand_6 PF13405.6 EJS41937.1 - 0.21 11.6 2.3 2.7 8.2 0.8 2.7 2 0 0 2 2 2 0 EF-hand domain LMBR1 PF04791.16 EJS41937.1 - 1.8 7.4 4.0 2 7.3 4.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc24 PF08286.11 EJS41937.1 - 3.6 7.9 12.4 3.6 7.9 1.5 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Mito_carr PF00153.27 EJS41938.1 - 1.5e-59 197.9 4.0 5.2e-19 68.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EJS41938.1 - 1.8e-13 50.7 4.1 7.5e-09 35.9 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EJS41938.1 - 2.1e-13 49.0 2.3 0.0038 17.0 0.2 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EJS41938.1 - 1.5e-11 43.0 5.0 0.0094 15.4 0.1 4.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EJS41938.1 - 6.6e-08 32.3 3.9 0.00028 20.7 0.3 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EJS41938.1 - 2.7e-06 26.6 0.6 0.0038 16.7 0.1 3.6 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 EJS41938.1 - 0.00099 19.4 0.0 0.026 14.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EJS41938.1 - 0.0097 16.2 0.9 5 7.5 0.1 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DNA_mis_repair PF01119.19 EJS41939.1 - 2.9e-24 85.0 0.3 7.5e-24 83.7 0.3 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EJS41939.1 - 1.9e-23 82.9 0.0 6.4e-23 81.1 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EJS41939.1 - 5.8e-10 39.1 0.0 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EJS41939.1 - 3.6e-07 30.7 0.0 9.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GlcNAc-1_reg PF18440.1 EJS41939.1 - 0.0062 16.7 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 Putative GlcNAc-1 phosphotransferase regulatory domain DUF2773 PF10971.8 EJS41939.1 - 0.17 12.1 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) Ribosomal_S13 PF00416.22 EJS41940.1 - 3.7e-18 66.2 0.0 5.4e-16 59.1 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EJS41940.1 - 0.0079 15.0 0.0 0.0079 15.0 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.8 EJS41940.1 - 0.019 15.3 0.1 0.079 13.3 0.0 2.0 2 0 0 2 2 2 0 IMS family HHH motif EOS1 PF12326.8 EJS41941.1 - 1.8e-61 207.1 0.9 1.8e-61 207.1 0.9 1.6 2 0 0 2 2 2 1 N-glycosylation protein Tropomyosin_1 PF12718.7 EJS41942.1 - 3.9e-56 189.2 59.7 1.1e-39 135.8 38.3 2.0 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 EJS41942.1 - 8.6e-10 38.4 52.2 4.5e-05 22.9 25.0 2.0 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.9 EJS41942.1 - 1.8e-05 24.9 42.4 0.06 13.6 13.9 3.1 1 1 2 3 3 3 3 Predicted coiled-coil domain-containing protein CENP-F_leu_zip PF10473.9 EJS41942.1 - 4.4e-05 23.5 12.9 4.4e-05 23.5 12.9 3.6 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 EJS41942.1 - 0.0011 18.8 40.7 0.073 12.9 18.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF724) DUF4201 PF13870.6 EJS41942.1 - 0.0019 17.9 45.4 0.066 12.9 26.8 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4201) ATG16 PF08614.11 EJS41942.1 - 0.0029 17.9 52.8 0.63 10.2 6.5 3.0 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 EJS41942.1 - 0.0033 17.4 64.9 0.17 11.9 9.1 4.1 1 1 3 4 4 4 3 TATA element modulatory factor 1 DNA binding IFP_35_N PF07334.13 EJS41942.1 - 0.0059 16.7 3.3 0.0059 16.7 3.3 4.6 3 2 2 5 5 4 2 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3450 PF11932.8 EJS41942.1 - 0.0067 15.8 45.6 0.17 11.2 13.8 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 EJS41942.1 - 0.0067 16.5 51.0 0.37 10.9 3.6 5.7 1 1 4 5 5 5 3 bZIP transcription factor GAS PF13851.6 EJS41942.1 - 0.013 14.8 53.6 0.15 11.4 26.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EJS41942.1 - 0.013 15.1 45.1 0.016 14.8 45.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein DivIC PF04977.15 EJS41942.1 - 0.014 15.1 53.0 0.1 12.4 7.9 5.2 1 1 4 5 5 5 0 Septum formation initiator Spc7 PF08317.11 EJS41942.1 - 0.019 13.9 52.1 0.079 11.8 16.7 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Rootletin PF15035.6 EJS41942.1 - 0.072 13.1 50.7 0.6 10.1 12.0 3.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4200 PF13863.6 EJS41942.1 - 0.073 13.5 56.3 11 6.5 27.7 4.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ERM PF00769.19 EJS41942.1 - 0.076 12.8 54.0 1 9.1 29.8 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CEP63 PF17045.5 EJS41942.1 - 0.082 12.8 44.9 0.14 12.0 32.4 2.1 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa HMMR_C PF15908.5 EJS41942.1 - 0.16 12.2 36.8 2.3 8.5 24.1 3.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal TPR_MLP1_2 PF07926.12 EJS41942.1 - 0.17 12.0 58.6 0.79 9.8 33.0 3.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.12 EJS41942.1 - 0.18 11.8 34.2 0.75 9.8 10.4 3.1 1 1 2 3 3 3 0 Laminin Domain II Cast PF10174.9 EJS41942.1 - 0.25 9.5 44.8 0.41 8.8 44.8 1.4 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ADIP PF11559.8 EJS41942.1 - 0.27 11.3 49.1 0.83 9.7 10.0 3.8 1 1 2 3 3 2 0 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 EJS41942.1 - 0.28 11.5 58.1 0.62 10.4 22.3 3.0 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region bZIP_2 PF07716.15 EJS41942.1 - 0.39 10.8 51.5 0.31 11.1 4.4 5.8 3 2 2 5 5 5 0 Basic region leucine zipper Yuri_gagarin PF15934.5 EJS41942.1 - 0.42 10.4 29.6 0.42 10.4 20.0 2.2 1 1 1 2 2 2 0 Yuri gagarin DUF3584 PF12128.8 EJS41942.1 - 0.51 7.8 42.3 0.56 7.7 42.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 EJS41942.1 - 0.51 10.9 65.0 4 8.0 31.4 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region ZapB PF06005.12 EJS41942.1 - 0.52 10.8 63.4 25 5.4 9.7 4.9 1 1 1 3 3 2 0 Cell division protein ZapB Ax_dynein_light PF10211.9 EJS41942.1 - 0.54 10.2 53.7 2.5 8.0 9.0 3.6 1 1 2 4 4 4 0 Axonemal dynein light chain Jnk-SapK_ap_N PF09744.9 EJS41942.1 - 0.6 10.3 55.7 2.9 8.1 35.0 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 FPP PF05911.11 EJS41942.1 - 0.86 7.7 49.0 0.99 7.5 24.2 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 EJS41942.1 - 0.88 10.0 45.8 0.25 11.8 24.2 2.1 1 1 1 2 2 2 0 Fez1 WXG100 PF06013.12 EJS41942.1 - 0.99 9.7 20.6 0.88 9.8 0.6 4.5 2 1 2 4 4 4 0 Proteins of 100 residues with WXG BLOC1_2 PF10046.9 EJS41942.1 - 1.3 9.4 41.9 5.3 7.4 8.7 4.1 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.12 EJS41942.1 - 1.5 6.9 42.4 0.39 8.8 9.0 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TMPIT PF07851.13 EJS41942.1 - 1.5 8.0 38.5 0.86 8.8 14.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein KASH_CCD PF14662.6 EJS41942.1 - 1.7 8.4 55.7 3.6 7.4 32.1 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DHR10 PF18595.1 EJS41942.1 - 1.9 8.5 55.5 7 6.7 15.9 3.3 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Swi5 PF07061.11 EJS41942.1 - 2.4 8.3 46.4 2.1 8.5 3.0 5.1 1 1 4 5 5 5 0 Swi5 DUF4446 PF14584.6 EJS41942.1 - 2.9 7.9 32.2 0.35 10.8 5.5 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF4446) DUF4164 PF13747.6 EJS41942.1 - 3.8 7.9 35.7 0.033 14.5 7.8 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) HMMR_N PF15905.5 EJS41942.1 - 4.6 6.6 54.0 14 5.0 27.6 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FUSC PF04632.12 EJS41942.1 - 4.7 5.6 6.0 5.1 5.5 6.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 EJS41942.1 - 7.9 6.5 28.7 5.3 7.1 11.1 3.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EJS41942.1 - 9.5 6.8 40.0 1.2 9.7 10.2 3.2 1 1 2 3 3 3 0 Protein of unknown function DUF16 DnaJ_C PF01556.18 EJS41943.1 - 3.2e-27 95.4 0.3 5e-27 94.8 0.3 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EJS41943.1 - 7.6e-23 80.4 2.3 1.5e-22 79.5 2.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EJS41943.1 - 4.5e-12 46.2 16.7 1.1e-11 44.9 16.7 1.7 1 0 0 1 1 1 1 DnaJ central domain ARL2_Bind_BART PF11527.8 EJS41943.1 - 0.12 12.5 1.6 0.25 11.5 1.6 1.5 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART HypA PF01155.19 EJS41943.1 - 0.26 11.3 5.3 6.2 6.9 0.6 2.8 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1752 PF08550.10 EJS41944.1 - 2.7e-08 33.5 0.1 8.4e-08 31.9 0.1 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Brix PF04427.18 EJS41945.1 - 3.3e-29 102.4 0.1 4.3e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 Brix domain tRNA-synt_2 PF00152.20 EJS41946.1 - 1.2e-58 198.7 0.1 1.6e-58 198.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EJS41946.1 - 7.2e-08 32.3 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EJS41946.1 - 2.1e-07 30.7 0.2 8.3e-05 22.2 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) DUF3231 PF11553.8 EJS41946.1 - 0.14 11.8 0.1 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3231) RNase_HII PF01351.18 EJS41947.1 - 3.4e-71 239.2 0.0 5e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII 2-oxoacid_dh PF00198.23 EJS41948.1 - 5e-74 248.7 1.2 6.7e-74 248.2 1.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EJS41948.1 - 3.6e-17 62.0 0.1 6.8e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EJS41948.1 - 4.2e-15 55.8 0.4 1.4e-14 54.1 0.4 2.0 1 0 0 1 1 1 1 e3 binding domain Tom7 PF08038.12 EJS41949.1 - 6.8e-18 64.0 0.1 9.1e-18 63.6 0.1 1.2 1 0 0 1 1 1 1 TOM7 family Forkhead PF00250.18 EJS41950.1 - 3.5e-34 116.9 0.4 1.2e-33 115.2 0.4 1.9 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 EJS41950.1 - 2.8e-12 46.8 0.1 9e-12 45.2 0.1 2.0 1 1 1 2 2 2 1 FHA domain Linker_histone PF00538.19 EJS41950.1 - 0.00089 19.6 0.3 0.0047 17.3 0.1 2.4 2 0 0 2 2 2 1 linker histone H1 and H5 family Ribosomal_L6 PF00347.23 EJS41951.1 - 3.3e-31 107.8 10.7 2.3e-16 60.2 4.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF2096 PF09869.9 EJS41951.1 - 0.0083 16.2 0.3 0.013 15.6 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2096) UAF_Rrn10 PF05234.11 EJS41951.1 - 0.19 12.0 1.2 0.25 11.6 0.3 1.7 2 0 0 2 2 2 0 UAF complex subunit Rrn10 SUN PF03856.13 EJS41952.1 - 1e-98 329.7 11.3 1.6e-98 329.1 11.3 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Macoilin PF09726.9 EJS41952.1 - 1.1 7.8 6.9 1.4 7.4 6.9 1.1 1 0 0 1 1 1 0 Macoilin family SWI-SNF_Ssr4 PF08549.10 EJS41952.1 - 1.3 7.5 4.4 1.8 7.1 4.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Apt1 PF10351.9 EJS41952.1 - 9.3 5.0 8.0 12 4.6 8.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DnaJ_C PF01556.18 EJS41953.1 - 1.2e-39 135.7 0.3 1.6e-39 135.3 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EJS41953.1 - 4.8e-26 90.7 1.4 8e-26 90.0 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EJS41953.1 - 3e-16 59.5 18.0 5.3e-16 58.7 18.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EJS41953.1 - 0.42 10.7 11.2 3.5 7.7 1.8 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EJS41953.1 - 1.1 9.3 17.1 0.24 11.4 2.6 2.8 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_C7 PF14522.6 EJS41953.1 - 8.3 6.5 8.6 5.2 7.1 4.7 2.2 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Gcd10p PF04189.13 EJS41954.1 - 7.3e-103 343.8 5.9 9.4e-103 343.4 5.9 1.1 1 0 0 1 1 1 1 Gcd10p family Mrr_N PF14338.6 EJS41954.1 - 0.0018 18.4 1.1 0.015 15.4 0.1 2.3 2 0 0 2 2 2 1 Mrr N-terminal domain CNP_C_terminal PF17839.1 EJS41954.1 - 0.22 12.2 3.2 0.4 11.4 0.0 2.5 2 1 0 2 2 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase Methyltr_RsmB-F PF01189.17 EJS41955.1 - 1.9e-82 275.8 0.0 3.9e-82 274.7 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EJS41955.1 - 2.9e-08 34.1 0.0 2e-07 31.4 0.0 2.5 2 1 1 3 3 3 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EJS41955.1 - 0.027 14.6 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase Actin PF00022.19 EJS41956.1 - 3.6e-56 190.5 0.0 5.3e-32 110.9 0.0 2.8 2 1 0 2 2 2 2 Actin Porin_3 PF01459.22 EJS41958.1 - 8.4e-69 232.0 1.1 9.4e-69 231.9 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Vac7 PF12751.7 EJS41959.1 - 3.7e-25 89.2 26.1 1.8e-20 73.8 5.7 5.5 2 1 3 6 6 6 2 Vacuolar segregation subunit 7 DUF3493 PF11998.8 EJS41959.1 - 0.013 15.6 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 DSPc PF00782.20 EJS41960.1 - 5.5e-38 129.8 0.1 1.1e-37 128.8 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EJS41960.1 - 7.1e-05 22.5 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EJS41960.1 - 0.077 13.1 0.3 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate MatP_C PF17414.2 EJS41960.1 - 0.098 12.9 0.3 0.29 11.3 0.3 1.8 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain PMSI1 PF15322.6 EJS41960.1 - 0.11 12.0 4.3 0.26 10.7 4.3 1.6 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative COX4 PF02936.14 EJS41961.1 - 3.8e-33 114.4 0.2 4.3e-33 114.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1289 PF06945.13 EJS41961.1 - 0.0084 15.9 0.7 2.5 8.0 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1289) N1221 PF07923.13 EJS41961.1 - 0.019 14.1 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 N1221-like protein Sec23_trunk PF04811.15 EJS41962.1 - 4e-66 223.0 0.1 1.7e-65 221.0 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EJS41962.1 - 7.2e-21 74.0 0.3 2e-20 72.5 0.3 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EJS41962.1 - 1.1e-15 58.1 0.5 2.7e-15 56.9 0.0 1.9 2 0 0 2 2 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EJS41962.1 - 2.2e-15 56.4 7.6 5e-15 55.3 7.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EJS41962.1 - 4.3e-07 29.7 0.0 9.3e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EJS41962.1 - 0.0023 17.3 1.4 0.0038 16.6 0.2 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain CDC45 PF02724.14 EJS41962.1 - 0.007 14.7 6.7 0.01 14.2 6.7 1.1 1 0 0 1 1 1 1 CDC45-like protein CobT PF06213.12 EJS41962.1 - 0.033 13.6 6.7 0.054 12.9 5.9 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.11 EJS41962.1 - 0.045 13.8 6.5 0.097 12.7 6.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 EJS41962.1 - 0.069 12.5 22.5 0.13 11.6 22.5 1.3 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 EJS41962.1 - 0.097 12.4 4.3 0.18 11.6 4.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.13 EJS41962.1 - 0.18 11.6 11.1 0.41 10.5 11.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 EJS41962.1 - 0.68 8.4 11.5 0.29 9.6 8.9 1.6 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CNDH2_C PF16858.5 EJS41962.1 - 0.96 9.3 4.8 1.6 8.5 4.8 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term PPP4R2 PF09184.11 EJS41962.1 - 1.3 8.6 14.0 3 7.4 13.6 1.7 2 0 0 2 2 2 0 PPP4R2 SDA1 PF05285.12 EJS41962.1 - 2 7.8 15.2 3 7.2 15.2 1.1 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 EJS41962.1 - 2.5 7.8 7.9 5.2 6.7 7.9 1.5 1 0 0 1 1 1 0 FAM176 family MRNIP PF15749.5 EJS41962.1 - 3.1 8.6 7.7 0.97 10.2 0.3 2.4 2 0 0 2 2 2 0 MRN-interacting protein SGT1 PF07093.11 EJS41962.1 - 4.5 5.6 9.5 7.3 4.9 9.5 1.2 1 0 0 1 1 1 0 SGT1 protein TFB6 PF17110.5 EJS41962.1 - 6.5 6.5 7.3 12 5.6 7.3 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH ALG11_N PF15924.5 EJS41963.1 - 2.1e-76 256.6 0.4 3.3e-76 256.0 0.4 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EJS41963.1 - 3.9e-22 78.6 0.0 6.7e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EJS41963.1 - 3.3e-06 27.6 0.0 6.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EJS41963.1 - 0.00019 21.5 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_28 PF03033.20 EJS41963.1 - 0.033 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Peptidase_M1 PF01433.20 EJS41965.1 - 5.3e-52 176.5 1.1 9.5e-52 175.7 1.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EJS41965.1 - 2.8e-36 125.5 0.3 4.5e-36 124.8 0.3 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Leuk-A4-hydro_C PF09127.11 EJS41965.1 - 1.8e-34 118.2 0.2 5.4e-34 116.7 0.2 1.9 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.6 EJS41965.1 - 0.14 11.8 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily DUF2722 PF10846.8 EJS41966.1 - 6.8e-58 196.8 25.7 9.3e-58 196.3 25.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) COG6 PF06419.11 EJS41967.1 - 8.6e-157 523.1 23.7 8.6e-157 523.1 23.7 1.9 1 1 0 2 2 2 1 Conserved oligomeric complex COG6 zf-AD PF07776.15 EJS41967.1 - 0.021 15.1 0.2 0.34 11.2 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) CdAMP_rec PF06153.11 EJS41967.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Cyclic-di-AMP receptor Pro_CA PF00484.19 EJS41968.1 - 1.5e-39 135.8 0.6 1.9e-39 135.5 0.6 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Iso_dh PF00180.20 EJS41969.1 - 3.3e-75 253.4 0.2 3.8e-75 253.2 0.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase tRNA_SAD PF07973.14 EJS41970.1 - 5.4e-09 36.0 0.2 1.6e-08 34.5 0.2 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 EJS41970.1 - 0.00019 20.1 0.0 0.00047 18.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (A) FERM_N PF09379.10 EJS41970.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 FERM N-terminal domain Mem_trans PF03547.18 EJS41971.1 - 5.4e-30 104.0 0.0 2.9e-29 101.7 0.0 1.9 1 1 0 1 1 1 1 Membrane transport protein DUF2183 PF09949.9 EJS41972.1 - 1.7e-30 105.2 0.1 5.1e-30 103.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EJS41972.1 - 0.0013 18.2 0.1 0.0044 16.5 0.0 1.8 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Mif2_N PF15624.6 EJS41972.1 - 0.87 10.3 4.1 2.6 8.8 4.1 1.7 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Ras PF00071.22 EJS41973.1 - 1.7e-55 187.1 0.1 2e-55 186.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS41973.1 - 1.5e-35 122.0 0.0 2.3e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS41973.1 - 4.9e-18 65.2 0.0 6.2e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EJS41973.1 - 1.1e-06 28.2 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EJS41973.1 - 1.7e-06 27.7 0.1 2.8e-06 27.0 0.1 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EJS41973.1 - 3.5e-06 27.0 0.5 0.059 13.3 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EJS41973.1 - 9.8e-06 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EJS41973.1 - 0.0042 17.5 0.0 0.0055 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NST1 PF13945.6 EJS41974.1 - 4e-14 53.2 4.8 4e-14 53.2 4.8 5.9 5 2 1 6 6 6 1 Salt tolerance down-regulator Ras PF00071.22 EJS41975.1 - 2.4e-50 170.3 0.0 2.8e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS41975.1 - 5.7e-22 78.2 0.0 7.7e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS41975.1 - 6.6e-09 35.5 0.0 1e-08 34.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EJS41975.1 - 0.0012 18.6 0.0 0.83 9.4 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EJS41975.1 - 0.044 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 EJS41975.1 - 0.066 13.0 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4930 PF16284.5 EJS41975.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4930) DNA_topoisoIV PF00521.20 EJS41976.1 - 2.8e-123 412.0 0.4 2.8e-123 412.0 0.4 2.1 3 0 0 3 3 3 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EJS41976.1 - 4.1e-49 166.1 4.4 2e-48 163.9 4.4 2.3 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EJS41976.1 - 7.4e-25 87.4 1.9 1.8e-24 86.2 1.9 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EJS41976.1 - 4.1e-14 53.1 0.1 2.5e-13 50.5 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EJS41976.1 - 2.5e-07 30.9 0.0 1.2e-06 28.6 0.0 2.2 1 0 0 1 1 1 1 Toprim domain Arm PF00514.23 EJS41977.1 - 3e-89 290.7 14.1 1.9e-12 46.7 0.2 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EJS41977.1 - 4.7e-28 97.5 7.2 1.2e-27 96.1 6.9 1.9 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 EJS41977.1 - 3.8e-22 77.6 3.7 2.4e-21 75.0 4.0 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 EJS41977.1 - 1.1e-19 70.6 3.5 8.9e-05 22.9 0.0 7.5 4 3 4 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 EJS41977.1 - 1.1e-13 51.4 0.6 0.0032 17.8 0.0 5.3 1 1 6 7 7 7 6 HEAT repeats HEAT PF02985.22 EJS41977.1 - 1.8e-11 43.3 0.0 1.6 9.2 0.0 7.6 7 0 0 7 7 7 2 HEAT repeat Arm_2 PF04826.13 EJS41977.1 - 1.1e-06 28.3 0.3 0.039 13.4 0.0 3.4 3 1 0 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.8 EJS41977.1 - 2.2e-06 27.8 0.6 0.1 12.7 0.0 4.3 3 3 1 4 4 4 3 V-ATPase subunit H Adaptin_N PF01602.20 EJS41977.1 - 7.1e-06 24.9 1.0 0.0024 16.5 0.0 3.5 1 1 0 1 1 1 1 Adaptin N terminal region RICTOR_V PF14668.6 EJS41977.1 - 2.5e-05 24.4 1.3 0.53 10.6 0.0 4.9 3 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.9 EJS41977.1 - 3e-05 24.0 0.5 0.055 13.5 0.0 4.2 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 EJS41977.1 - 0.019 15.6 0.8 56 4.8 0.1 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat FAST_1 PF06743.15 EJS41977.1 - 0.091 12.7 0.5 1 9.3 0.0 2.8 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 PUL PF08324.11 EJS41977.1 - 0.098 11.9 4.9 0.76 9.0 0.1 3.0 1 1 1 2 2 2 0 PUL domain NOPS PF08075.11 EJS41978.1 - 0.057 13.6 0.2 0.3 11.3 0.2 2.3 1 0 0 1 1 1 0 NOPS (NUC059) domain Lactonase PF10282.9 EJS41979.1 - 0.077 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Qn_am_d_aII PF14930.6 EJS41979.1 - 0.12 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II UCH PF00443.29 EJS41980.1 - 3.8e-52 177.3 3.3 1.1e-51 175.9 3.3 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJS41980.1 - 3.8e-15 56.3 12.4 4.5e-15 56.1 6.3 3.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L11 PF00298.19 EJS41981.1 - 3e-26 91.7 0.3 4.7e-26 91.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EJS41981.1 - 4.6e-25 87.2 0.5 7.4e-25 86.6 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain ANAPC4_WD40 PF12894.7 EJS41982.1 - 5.9e-06 26.5 0.2 0.0063 16.8 0.0 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJS41982.1 - 0.00035 21.3 1.0 1.5 9.8 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat HPS3_N PF14761.6 EJS41982.1 - 0.0035 16.9 1.7 0.037 13.6 0.3 3.0 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3 CBM_19 PF03427.13 EJS41982.1 - 0.0041 17.1 2.7 0.055 13.5 0.4 2.6 2 0 0 2 2 2 1 Carbohydrate binding domain (family 19) DUF812 PF05667.11 EJS41982.1 - 0.0042 16.0 2.3 0.006 15.5 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AP1AR PF15745.5 EJS41982.1 - 0.021 14.5 0.1 0.041 13.5 0.1 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein MRP-L28 PF09812.9 EJS41982.1 - 0.046 13.9 0.8 0.18 12.0 0.3 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 SKA2 PF16740.5 EJS41982.1 - 0.077 12.8 0.8 0.18 11.6 0.8 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Sec34 PF04136.15 EJS41982.1 - 0.16 11.9 2.5 0.42 10.5 2.5 1.7 1 0 0 1 1 1 0 Sec34-like family Ras PF00071.22 EJS41983.1 - 4.2e-44 150.0 0.0 1.4e-29 102.8 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EJS41983.1 - 3.6e-17 62.7 2.3 1.4e-08 34.9 0.0 3.8 4 1 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS41983.1 - 3.6e-06 26.5 0.0 0.018 14.5 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Macoilin PF09726.9 EJS41983.1 - 5.2 5.5 17.1 6.4 5.2 17.1 1.1 1 0 0 1 1 1 0 Macoilin family Ribosomal_S3_C PF00189.20 EJS41984.1 - 3.9e-23 81.8 0.4 2e-22 79.5 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EJS41984.1 - 5.3e-12 45.4 0.0 2.8e-11 43.1 0.1 2.1 2 0 0 2 2 2 1 KH domain Syndecan PF01034.20 EJS41985.1 - 0.12 12.3 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain RRM_1 PF00076.22 EJS41986.1 - 1.8e-25 88.5 0.6 1e-16 60.5 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJS41986.1 - 4.9e-05 23.4 0.2 0.12 12.5 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif AMPK1_CBM PF16561.5 EJS41987.1 - 7.6e-14 51.7 0.1 1.7e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Med8 PF10232.9 EJS41987.1 - 0.94 9.0 11.5 0.4 10.2 9.0 1.7 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 CDC45 PF02724.14 EJS41987.1 - 4 5.6 11.0 4.8 5.3 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein PS_Dcarbxylase PF02666.15 EJS41988.1 - 2.9e-69 232.6 0.0 3.9e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 EJS41988.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 MNLL subunit Peptidase_M23 PF01551.22 EJS41988.1 - 0.017 15.3 0.3 0.8 9.9 0.1 2.7 2 0 0 2 2 2 0 Peptidase family M23 FAA_hydrolase PF01557.18 EJS41989.1 - 2.1e-48 164.9 0.0 2.6e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family bZIP_1 PF00170.21 EJS41990.1 - 2.7e-07 30.6 2.7 2.7e-07 30.6 2.7 2.2 2 0 0 2 2 2 1 bZIP transcription factor Aft1_OSA PF11785.8 EJS41990.1 - 1.1e-05 25.8 0.5 1.1e-05 25.8 0.5 2.5 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 EJS41990.1 - 8.9e-05 22.5 5.4 8.9e-05 22.5 5.4 2.1 2 0 0 2 2 2 1 Basic region leucine zipper Aft1_HRA PF11786.8 EJS41990.1 - 0.017 15.4 8.0 0.017 15.4 8.0 4.0 3 2 2 5 5 5 0 Aft1 HRA domain DUF1043 PF06295.12 EJS41990.1 - 8.8 6.4 7.4 19 5.3 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Med21 PF11221.8 EJS41991.1 - 3 8.1 9.8 3.9 7.7 3.4 2.9 2 1 0 2 2 2 0 Subunit 21 of Mediator complex HtaA PF04213.13 EJS41993.1 - 0.17 12.4 0.0 0.43 11.0 0.0 1.6 1 1 0 1 1 1 0 Htaa GTP_EFTU PF00009.27 EJS41994.1 - 7.2e-58 195.3 0.0 1.1e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EJS41994.1 - 7.8e-14 51.5 0.0 2e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EJS41994.1 - 1.1e-10 41.7 0.0 2.7e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EJS41994.1 - 6.1e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EJS41994.1 - 0.00037 20.3 0.0 0.0024 17.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EJS41994.1 - 0.007 16.4 0.0 0.026 14.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Pkinase PF00069.25 EJS41995.1 - 2.5e-59 200.8 12.9 9.5e-42 143.2 0.2 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJS41995.1 - 1.7e-24 86.5 0.4 1.1e-20 74.0 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EJS41995.1 - 0.035 14.0 8.1 0.8 9.6 0.1 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EJS41995.1 - 0.053 12.6 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RR_TM4-6 PF06459.12 EJS41995.1 - 1.5 8.6 21.2 4.4 7.0 21.2 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 EJS41995.1 - 1.6 8.1 11.1 3.5 7.0 11.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CPSF100_C PF13299.6 EJS41995.1 - 5.2 7.2 14.6 21 5.3 14.6 2.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal LMBR1 PF04791.16 EJS41995.1 - 6.1 5.6 8.6 9.4 5.0 8.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 EJS41995.1 - 6.9 5.9 24.2 8.5 5.6 21.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AIF_C PF14721.6 EJS41995.1 - 8.1 6.8 12.6 35 4.8 12.6 2.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Asparaginase PF00710.20 EJS41996.1 - 0.00023 20.7 3.0 0.00052 19.6 1.1 2.4 2 1 0 2 2 2 1 Asparaginase, N-terminal Endosulfine PF04667.17 EJS41998.1 - 2.1e-29 101.5 0.6 3.2e-29 100.9 0.6 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region INSIG PF07281.12 EJS41999.1 - 1.3e-19 70.7 4.8 2.3e-18 66.6 1.4 2.2 1 1 1 2 2 2 2 Insulin-induced protein (INSIG) zf-AN1 PF01428.16 EJS42000.1 - 4.6e-11 42.7 12.9 7.7e-11 42.0 12.9 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger RE_NgoBV PF09564.10 EJS42000.1 - 7.7e-05 22.2 0.6 0.00011 21.7 0.6 1.1 1 0 0 1 1 1 1 NgoBV restriction endonuclease CEL_III_C PF18054.1 EJS42000.1 - 0.0015 18.6 0.2 0.0036 17.4 0.2 1.6 1 0 0 1 1 1 1 CEL-III C-terminal PSI_integrin PF17205.3 EJS42000.1 - 0.24 11.2 7.1 3.2 7.6 7.1 2.6 1 1 0 1 1 1 0 Integrin plexin domain Pkinase PF00069.25 EJS42001.1 - 1.9e-24 86.4 0.0 1.9e-24 86.4 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42001.1 - 1.9e-12 47.1 0.1 4.8e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJS42001.1 - 2e-09 36.8 0.0 2e-09 36.8 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase DUF737 PF05300.11 EJS42001.1 - 0.00021 21.7 14.0 0.0003 21.2 14.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF737) ERM PF00769.19 EJS42001.1 - 0.9 9.3 32.6 1.6 8.5 32.6 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Prefoldin_2 PF01920.20 EJS42002.1 - 1.5e-21 76.3 7.9 1.8e-21 76.1 7.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit UPF0054 PF02130.17 EJS42002.1 - 0.0095 15.7 0.3 0.012 15.4 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 PGA2 PF07543.12 EJS42003.1 - 1.3e-11 44.6 8.5 1.1e-06 28.6 0.8 2.1 1 1 1 2 2 2 2 Protein trafficking PGA2 MscS_TM PF12794.7 EJS42003.1 - 0.7 8.7 2.3 0.41 9.5 0.2 1.5 1 1 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 VPS11_C PF12451.8 EJS42003.1 - 2.7 8.3 6.5 0.3 11.4 1.7 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal CAP_GLY PF01302.25 EJS42004.1 - 2.3e-15 56.4 0.1 4.4e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EJS42004.1 - 3.7e-07 30.5 0.0 5.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain TcpE PF12648.7 EJS42005.1 - 0.071 13.7 0.1 0.071 13.7 0.1 1.9 2 0 0 2 2 2 0 TcpE family MFA1_2 PF17317.2 EJS42006.1 - 5e-23 80.6 0.6 5.5e-23 80.4 0.6 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 LOR PF04525.12 EJS42006.1 - 0.029 13.9 0.0 0.029 13.9 0.0 1.0 1 0 0 1 1 1 0 LURP-one-related Ammonium_transp PF00909.21 EJS42007.1 - 2.2e-130 434.9 29.2 2.6e-130 434.7 29.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family A_deaminase PF00962.22 EJS42008.1 - 2.7e-101 339.2 0.0 3e-101 339.0 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase THOC2_N PF16134.5 EJS42009.1 - 8.6e-179 596.2 11.4 1.5e-178 595.4 11.4 1.4 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EJS42009.1 - 1e-41 143.1 20.5 1.1e-41 143.0 7.9 3.7 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EJS42009.1 - 2e-23 82.2 0.3 5.7e-23 80.8 0.3 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit CAP_N PF01213.19 EJS42010.1 - 2.3e-111 372.3 0.5 2.3e-111 372.3 0.5 1.6 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EJS42010.1 - 1.1e-60 203.8 1.0 2.7e-60 202.5 0.8 1.7 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal Mito_fiss_reg PF05308.11 EJS42010.1 - 0.25 11.4 7.2 2.6 8.0 3.4 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Dscam_C PF12355.8 EJS42010.1 - 3.1 8.8 7.8 0.14 13.2 1.6 2.0 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal S4 PF01479.25 EJS42011.1 - 2.3e-17 62.4 0.0 4.9e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EJS42011.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 S4 domain Eaf7 PF07904.13 EJS42012.1 - 2.2e-35 121.2 1.0 2.2e-35 121.2 1.0 5.0 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 FKBP_C PF00254.28 EJS42013.1 - 1.4e-33 115.0 0.0 1.7e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GNAT_acetyltr_2 PF13718.6 EJS42014.1 - 2.1e-99 331.6 3.4 2.4e-99 331.4 0.0 2.7 3 0 0 3 3 3 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EJS42014.1 - 1.1e-91 306.7 11.6 2.4e-91 305.6 11.6 1.6 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EJS42014.1 - 7.7e-66 221.3 0.0 3.9e-65 219.0 0.0 2.3 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.11 EJS42014.1 - 5.8e-34 115.9 0.3 2e-33 114.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 EJS42014.1 - 0.0072 16.6 0.0 0.77 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 EJS42014.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase L1R_F9L PF02442.17 EJS42014.1 - 0.13 12.1 1.2 0.29 11.0 1.2 1.5 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Tom22 PF04281.13 EJS42015.1 - 3.5e-48 162.9 2.0 3.9e-48 162.7 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 AAA_18 PF13238.6 EJS42016.1 - 1.7e-07 31.8 0.2 9.9e-07 29.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 EJS42016.1 - 2e-06 27.7 0.1 3.7e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 EJS42016.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase CPT PF07931.12 EJS42016.1 - 0.0049 16.7 0.0 0.06 13.2 0.0 2.4 2 1 1 3 3 3 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EJS42016.1 - 0.017 15.3 0.1 0.049 13.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EJS42016.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain GCP_N_terminal PF17681.1 EJS42017.1 - 3.6e-32 112.2 4.5 3.6e-32 112.2 4.5 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EJS42017.1 - 2e-30 106.3 0.9 2e-30 106.3 0.9 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal DUF4100 PF13352.6 EJS42017.1 - 0.16 11.8 0.2 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) TetR_C_8 PF14278.6 EJS42017.1 - 8.8 6.5 9.6 11 6.2 2.3 3.5 2 1 0 2 2 2 0 Transcriptional regulator C-terminal region MFS_1 PF07690.16 EJS42018.1 - 3.1e-29 102.0 52.8 4.5e-22 78.5 40.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EJS42018.1 - 0.00029 19.8 12.4 0.037 12.9 1.3 2.4 2 1 0 2 2 2 2 MFS_1 like family Vma12 PF11712.8 EJS42018.1 - 7.1 6.7 6.2 3.6 7.7 2.3 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PDZ_1 PF12812.7 EJS42019.1 - 1.2e-51 172.7 0.8 1.5e-35 121.1 0.0 3.5 4 0 0 4 4 4 2 PDZ-like domain Trypsin_2 PF13365.6 EJS42019.1 - 1.7e-23 84.2 0.0 2.7e-19 70.5 0.0 2.6 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ PF00595.24 EJS42019.1 - 8.1e-14 51.7 0.2 2.3e-09 37.5 0.0 2.9 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EJS42019.1 - 7e-12 45.0 1.9 8.3e-05 22.4 0.2 4.1 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 EJS42019.1 - 3.4e-11 43.3 1.0 0.00043 20.6 0.1 3.7 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 EJS42019.1 - 3.3e-05 23.8 0.5 0.28 11.2 0.1 3.2 3 0 0 3 3 3 2 Tricorn protease PDZ domain Trypsin PF00089.26 EJS42019.1 - 0.0024 17.7 0.0 0.0061 16.4 0.0 1.6 1 1 0 1 1 1 1 Trypsin DUF31 PF01732.16 EJS42019.1 - 0.018 14.6 0.2 0.03 13.9 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) DDE_5 PF13546.6 EJS42019.1 - 0.14 11.5 0.0 0.37 10.1 0.0 1.6 2 0 0 2 2 2 0 DDE superfamily endonuclease Peptidase_S7 PF00949.21 EJS42019.1 - 0.17 11.7 0.1 0.38 10.6 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease TPR_2 PF07719.17 EJS42020.1 - 2.3e-28 96.0 20.8 9.3e-05 22.3 0.0 11.5 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 EJS42020.1 - 1.1e-27 94.7 26.7 1.2e-06 28.1 2.5 11.0 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 EJS42020.1 - 2.7e-23 82.3 0.0 0.00056 20.5 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EJS42020.1 - 4.7e-18 63.8 20.9 0.00094 19.2 0.0 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EJS42020.1 - 1.3e-16 59.8 4.8 0.17 12.8 0.0 9.6 6 3 5 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EJS42020.1 - 6.3e-16 58.4 8.3 0.0073 16.6 0.3 7.7 7 4 1 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 EJS42020.1 - 5.4e-15 55.7 8.1 8.6e-05 23.0 0.6 7.1 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EJS42020.1 - 6.7e-15 54.5 17.0 0.0084 15.8 0.1 7.6 5 2 2 7 7 7 4 TPR repeat TPR_17 PF13431.6 EJS42020.1 - 7.5e-11 41.6 8.2 0.0015 18.8 0.2 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EJS42020.1 - 1.3e-08 34.9 6.3 0.0059 16.8 0.0 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EJS42020.1 - 1.9e-08 33.7 4.3 0.7 10.1 0.1 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 EJS42020.1 - 4.7e-07 29.9 0.0 0.3 11.3 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EJS42020.1 - 1.1e-05 25.1 0.0 0.11 11.8 1.1 3.5 2 1 2 4 4 4 2 MalT-like TPR region HrpB1_HrpK PF09613.10 EJS42020.1 - 9.7e-05 22.0 0.1 0.22 11.2 0.2 3.4 4 0 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) Glyco_trans_A_1 PF09318.10 EJS42020.1 - 0.0042 16.8 1.6 0.0091 15.7 1.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 1 domain A MIT PF04212.18 EJS42020.1 - 0.0056 16.7 9.9 2.6 8.2 0.0 5.6 4 2 1 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 EJS42020.1 - 0.0084 15.8 13.7 0.12 12.1 0.4 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat-like domain Exonuc_VII_S PF02609.16 EJS42020.1 - 0.013 15.5 2.7 0.033 14.2 0.7 2.7 2 0 0 2 2 2 0 Exonuclease VII small subunit TPR_10 PF13374.6 EJS42020.1 - 0.018 14.9 5.6 9.9 6.2 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 EJS42020.1 - 0.022 15.0 3.4 1.7e+02 2.8 0.1 6.1 6 0 0 6 6 5 0 PPR repeat PTS_IIA PF02255.16 EJS42020.1 - 0.078 13.0 4.1 54 3.9 0.0 4.0 4 0 0 4 4 3 0 PTS system, Lactose/Cellobiose specific IIA subunit PPTA PF01239.22 EJS42020.1 - 0.11 12.3 0.3 1.9 8.4 0.3 2.8 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat SHNi-TPR PF10516.9 EJS42020.1 - 0.12 11.8 3.9 8.1 6.0 0.1 4.2 3 0 0 3 3 3 0 SHNi-TPR DUF3808 PF10300.9 EJS42020.1 - 0.14 10.9 6.5 0.41 9.3 0.2 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF3808) TPR_6 PF13174.6 EJS42020.1 - 0.34 11.6 15.9 35 5.3 0.1 7.7 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF2225 PF09986.9 EJS42020.1 - 0.79 9.4 7.8 1.5 8.5 0.3 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) PPR_2 PF13041.6 EJS42020.1 - 0.83 9.9 3.0 79 3.6 0.1 4.6 4 0 0 4 4 4 0 PPR repeat family DUF2681 PF10883.8 EJS42020.1 - 2.2 8.7 5.3 0.33 11.4 0.6 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) CTU2 PF10288.9 EJS42021.1 - 6.3e-22 77.9 0.4 1.5e-21 76.7 0.4 1.7 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 DCP2 PF05026.13 EJS42022.1 - 9.7e-27 93.1 1.1 2.3e-26 91.9 1.1 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EJS42022.1 - 3.2e-13 49.8 0.0 7.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Malate_synthase PF01274.22 EJS42023.1 - 3.4e-228 758.2 0.0 3.9e-228 758.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase FHA PF00498.26 EJS42024.1 - 2e-15 56.9 0.1 5.6e-15 55.5 0.1 1.8 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EJS42024.1 - 9.6e-10 38.0 10.9 1.8e-09 37.2 10.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EJS42024.1 - 1.5e-05 25.2 13.4 2.6e-05 24.5 13.4 1.4 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EJS42024.1 - 0.00075 19.8 0.0 0.0025 18.1 0.0 1.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 EJS42024.1 - 0.014 15.3 10.7 0.023 14.6 10.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EJS42024.1 - 0.043 13.7 12.5 0.076 12.9 12.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EJS42024.1 - 0.061 13.4 4.6 0.13 12.4 4.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sec_GG PF07549.14 EJS42024.1 - 0.097 12.2 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-rbx1 PF12678.7 EJS42024.1 - 0.18 12.2 8.4 0.39 11.0 8.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EJS42024.1 - 0.48 10.3 12.6 0.81 9.6 12.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJS42024.1 - 6.2 6.9 11.2 12 6.0 11.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF2417 PF10329.9 EJS42025.1 - 2.2e-82 276.0 8.2 3e-82 275.6 8.2 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 EJS42025.1 - 1.2e-25 90.6 0.0 1.8e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJS42025.1 - 0.0052 17.4 0.0 0.0076 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family RNA_pol_L_2 PF13656.6 EJS42026.1 - 4.4e-34 116.1 0.0 7.2e-34 115.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EJS42026.1 - 2.3e-15 55.8 0.0 3.5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cyt-b5 PF00173.28 EJS42027.1 - 8.9e-24 83.4 0.2 1.1e-23 83.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.22 EJS42028.1 - 6.5e-18 64.3 0.0 1.5e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2129 PF09902.9 EJS42028.1 - 0.11 12.6 3.5 1.3 9.2 0.1 3.3 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2129) CDC45 PF02724.14 EJS42028.1 - 0.31 9.3 8.5 0.31 9.3 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EJS42028.1 - 2.8 6.8 6.5 4.2 6.3 6.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EJS42028.1 - 4.3 6.0 8.1 4.8 5.8 8.1 1.2 1 0 0 1 1 1 0 Presenilin His_Phos_1 PF00300.22 EJS42029.1 - 8.4e-18 64.8 0.0 1.2e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) YEATS PF03366.16 EJS42030.1 - 3.7e-35 119.7 0.3 5.9e-35 119.1 0.3 1.3 1 0 0 1 1 1 1 YEATS family GPS2_interact PF15784.5 EJS42030.1 - 0.015 15.7 0.6 0.031 14.7 0.6 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Osmo_CC PF08946.10 EJS42030.1 - 0.073 13.3 7.0 0.15 12.3 7.0 1.5 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF3914 PF13053.6 EJS42030.1 - 0.091 13.1 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) Syja_N PF02383.18 EJS42031.1 - 1.1e-77 261.5 0.5 2e-77 260.7 0.5 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EJS42031.1 - 8.3e-17 61.5 0.1 1.2e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family bZIP_2 PF07716.15 EJS42032.1 - 0.00056 19.9 3.1 0.00056 19.9 3.1 2.4 2 0 0 2 2 2 1 Basic region leucine zipper Spt5_N PF11942.8 EJS42032.1 - 0.013 16.5 6.3 0.013 16.5 6.3 3.4 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal PspB PF06667.12 EJS42032.1 - 0.024 14.7 1.8 0.063 13.3 1.8 1.7 1 0 0 1 1 1 0 Phage shock protein B DNA_pol_B PF00136.21 EJS42033.1 - 3.6e-124 415.0 1.1 5.6e-124 414.3 1.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EJS42033.1 - 1.3e-63 214.1 6.0 2.6e-63 213.1 6.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EJS42033.1 - 3e-57 194.3 0.0 6.7e-57 193.1 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EJS42033.1 - 1e-18 67.1 12.1 1e-18 67.1 12.1 2.2 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Aa_trans PF01490.18 EJS42034.1 - 8.1e-108 360.7 37.0 9.7e-108 360.5 37.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MttA_Hcf106 PF02416.16 EJS42034.1 - 3.4 7.1 4.3 23 4.4 0.1 2.6 2 0 0 2 2 2 0 mttA/Hcf106 family ApoO PF09769.9 EJS42035.1 - 1.6e-05 24.8 1.7 0.96 9.4 0.0 3.5 2 1 1 3 3 3 3 Apolipoprotein O Y_phosphatase2 PF03162.13 EJS42036.1 - 9.8e-60 200.9 0.0 2e-59 199.8 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EJS42036.1 - 2.4e-05 24.4 0.0 5.9e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EJS42036.1 - 0.034 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EJS42036.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Rick_17kDa_Anti PF05433.15 EJS42037.1 - 8.3e-10 38.4 2.4 8.3e-10 38.4 2.4 2.4 3 0 0 3 3 3 1 Glycine zipper 2TM domain RIO1 PF01163.22 EJS42038.1 - 5.2e-42 143.6 0.2 8.2e-42 142.9 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EJS42038.1 - 3.2e-32 110.6 0.1 6.5e-32 109.6 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EJS42038.1 - 5.6e-06 26.5 0.1 0.16 11.9 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EJS42038.1 - 0.00053 19.4 0.1 0.1 11.9 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EJS42038.1 - 0.055 12.2 0.0 0.079 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase ArfGap PF01412.18 EJS42039.1 - 2.5e-21 75.9 0.7 4.8e-21 75.0 0.7 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SMK-1 PF04802.15 EJS42040.1 - 4.8e-60 202.7 4.2 4.8e-60 202.7 4.2 2.6 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 HEAT PF02985.22 EJS42040.1 - 0.061 13.6 0.1 4.6 7.8 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat UCH_C PF18031.1 EJS42040.1 - 0.098 12.6 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases YjeF_N PF03853.15 EJS42041.1 - 7e-35 120.4 0.0 8.3e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus NYD-SP28 PF14772.6 EJS42042.1 - 0.061 13.4 0.2 0.061 13.4 0.2 2.3 2 0 0 2 2 2 0 Sperm tail RRM_1 PF00076.22 EJS42043.1 - 1.2e-18 66.7 0.0 1.1e-16 60.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUR7 PF06687.12 EJS42045.1 - 7.7e-38 130.2 15.8 1e-37 129.9 15.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family MerC PF03203.14 EJS42045.1 - 0.013 16.0 1.9 0.013 16.0 1.9 1.8 2 0 0 2 2 2 0 MerC mercury resistance protein DUF373 PF04123.13 EJS42045.1 - 1.2 8.5 3.6 1.9 7.9 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) SecA_SW PF07516.13 EJS42046.1 - 0.17 11.9 1.0 0.31 11.0 0.4 1.7 2 0 0 2 2 2 0 SecA Wing and Scaffold domain Chitin_synth_1 PF01644.17 EJS42047.1 - 1.1e-68 230.3 0.2 1.9e-68 229.5 0.2 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EJS42047.1 - 8.6e-26 89.7 0.3 1.7e-25 88.7 0.3 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EJS42047.1 - 8.3e-16 57.7 11.2 2.8e-12 46.0 2.5 2.6 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EJS42047.1 - 5.8e-10 39.4 4.7 2.2e-09 37.5 4.7 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EJS42047.1 - 0.016 15.0 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EJS42047.1 - 0.025 14.5 0.0 0.082 12.8 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF3488 PF11992.8 EJS42047.1 - 2 7.3 9.0 3.4 6.5 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) GATase_4 PF13230.6 EJS42048.1 - 4.6e-15 55.2 0.0 2.5e-13 49.6 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 EJS42048.1 - 1e-09 38.7 0.0 1.8e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3251 PF11622.8 EJS42049.1 - 0.076 12.7 0.0 14 5.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3251) OCRE PF17780.1 EJS42049.1 - 0.18 11.8 13.9 16 5.6 0.2 5.1 1 1 4 5 5 5 0 OCRE domain WSC PF01822.19 EJS42050.1 - 2.1e-08 34.2 12.7 2.1e-08 34.2 12.7 3.5 2 1 0 2 2 2 1 WSC domain LRR19-TM PF15176.6 EJS42050.1 - 0.0016 18.4 0.0 0.0073 16.3 0.0 2.1 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain SKG6 PF08693.10 EJS42050.1 - 0.0041 16.5 2.9 0.048 13.1 2.9 3.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 EJS42050.1 - 0.071 14.0 2.4 0.13 13.1 0.0 2.6 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EJS42050.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain TMEM190 PF15431.6 EJS42050.1 - 0.39 10.9 0.0 0.39 10.9 0.0 3.4 4 1 0 4 4 4 0 Transmembrane protein 190 Orf78 PF06024.12 EJS42050.1 - 2.6 8.4 8.2 1.5e+02 2.8 8.2 3.4 1 1 0 1 1 1 0 Orf78 (ac78) Utp14 PF04615.13 EJS42050.1 - 9.8 4.6 25.5 17 3.8 25.5 1.3 1 0 0 1 1 1 0 Utp14 protein Aha1_N PF09229.11 EJS42051.1 - 2.2e-29 102.4 0.0 2.9e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal ERG4_ERG24 PF01222.17 EJS42052.1 - 3.9e-187 622.3 13.1 4.4e-187 622.1 13.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EJS42052.1 - 1.9e-06 27.6 1.0 1.9e-06 27.6 1.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Abhydrolase_1 PF00561.20 EJS42053.1 - 1.3e-81 274.1 0.0 1.5e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJS42053.1 - 0.00022 21.9 0.0 0.00037 21.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJS42053.1 - 0.065 12.5 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Plasmodium_Vir PF05795.11 EJS42053.1 - 0.24 10.8 4.6 0.39 10.1 4.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein HCO3_cotransp PF00955.21 EJS42054.1 - 1.1e-77 262.0 15.1 4.4e-42 144.6 4.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family Sec2p PF06428.11 EJS42055.1 - 1.2e-27 95.7 13.4 1.2e-27 95.7 13.4 4.4 2 1 2 4 4 4 2 GDP/GTP exchange factor Sec2p DUF4073 PF13285.6 EJS42055.1 - 0.024 14.3 0.7 0.08 12.6 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) FH2 PF02181.23 EJS42056.1 - 1e-90 304.6 6.7 1e-90 304.6 6.7 4.1 4 1 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 EJS42056.1 - 1.5e-43 148.7 5.2 1.5e-43 148.7 5.2 4.2 4 1 1 5 5 5 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 EJS42056.1 - 4.3e-25 88.4 1.8 1.7e-19 70.1 0.1 5.9 6 0 0 6 6 6 2 Diaphanous GTPase-binding Domain Sin3_corepress PF08295.12 EJS42056.1 - 0.57 10.3 7.0 0.16 12.1 1.3 3.3 2 1 0 2 2 2 0 Sin3 family co-repressor Dfp1_Him1_M PF08630.10 EJS42056.1 - 6.4 7.0 12.1 1.9 8.7 4.3 3.7 2 0 0 2 2 2 0 Dfp1/Him1, central region AA_permease PF00324.21 EJS42057.1 - 7.1e-146 486.6 44.4 8.1e-146 486.4 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS42057.1 - 1.2e-30 106.7 48.3 1.8e-30 106.1 48.3 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJS42058.1 - 1.2e-137 459.5 47.2 1.4e-137 459.2 47.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS42058.1 - 2.2e-30 105.8 50.8 2.6e-30 105.6 50.8 1.1 1 0 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.8 EJS42058.1 - 0.0034 17.0 4.4 0.2 11.3 0.7 3.1 2 0 0 2 2 2 2 Intrinsic membrane protein PufX PI3_PI4_kinase PF00454.27 EJS42059.1 - 8.4e-32 111.0 0.2 4e-31 108.7 0.2 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 EJS42059.1 - 3.3e-22 78.2 2.4 8.7e-22 76.8 2.4 1.8 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 EJS42059.1 - 3.1e-06 26.7 0.6 9.6e-06 25.1 0.6 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF148 PF02520.17 EJS42059.1 - 0.038 14.1 0.4 0.15 12.2 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF148 Na_Ca_ex_C PF16494.5 EJS42059.1 - 0.11 12.9 1.5 0.36 11.3 0.3 2.4 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain CRAL_TRIO PF00650.20 EJS42060.1 - 4.4e-38 130.5 0.1 6.9e-38 129.9 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJS42060.1 - 7.3e-18 64.5 0.3 1.5e-17 63.5 0.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EJS42060.1 - 0.0029 17.8 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain YIF1 PF03878.15 EJS42061.1 - 4.8e-77 258.7 4.9 7.2e-77 258.1 4.9 1.3 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EJS42061.1 - 7.7e-07 29.0 2.2 1.8e-06 27.8 2.2 1.6 1 0 0 1 1 1 1 Yip1 domain ORC5_C PF14630.6 EJS42062.1 - 4e-62 210.3 0.4 6.6e-62 209.6 0.4 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EJS42062.1 - 3.9e-06 27.3 0.0 8.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EJS42062.1 - 1.4e-05 25.4 0.0 3.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EJS42062.1 - 0.021 14.9 0.1 0.07 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EJS42062.1 - 0.19 11.7 1.6 2.6 7.9 1.6 2.3 1 1 0 1 1 1 0 NACHT domain HMA PF00403.26 EJS42063.1 - 8.7e-08 32.5 0.1 1.1e-07 32.2 0.1 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Dsl1_N PF11988.8 EJS42064.1 - 3.2e-132 440.8 25.9 5.4e-132 440.0 25.9 1.4 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 N terminal Dsl1_C PF11989.8 EJS42064.1 - 2.5e-89 298.2 4.4 2.5e-89 298.2 4.4 2.9 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal TetR_C_4 PF08359.11 EJS42064.1 - 0.039 14.1 0.0 0.15 12.2 0.0 2.0 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region Mating_N PF12731.7 EJS42064.1 - 4.8 7.3 8.0 7.2 6.8 1.2 3.6 2 2 1 3 3 3 0 Mating-type protein beta 1 SDA1 PF05285.12 EJS42064.1 - 7.9 5.8 18.4 12 5.2 18.4 1.2 1 0 0 1 1 1 0 SDA1 Pterin_bind PF00809.22 EJS42065.1 - 8.1e-54 182.9 0.1 2.1e-53 181.5 0.1 1.7 1 1 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 EJS42065.1 - 1.3e-36 125.5 0.1 4.1e-18 66.0 0.2 2.6 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 EJS42065.1 - 1.3e-34 119.1 0.1 1e-33 116.2 0.0 2.4 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PknH_C PF14032.6 EJS42065.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 PknH-like extracellular domain zf-CCHC PF00098.23 EJS42066.1 - 6.4e-54 177.8 56.3 2.2e-08 33.8 1.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EJS42066.1 - 1.6e-13 50.1 43.2 0.0099 15.6 0.4 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 EJS42066.1 - 6.3e-07 29.3 48.1 0.059 13.3 0.7 7.0 1 1 6 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 EJS42066.1 - 1.3e-06 28.0 36.0 0.38 10.5 0.1 7.1 3 3 4 7 7 7 6 GAG-polyprotein viral zinc-finger zf-C2H2_10 PF16588.5 EJS42066.1 - 0.011 15.5 1.7 0.011 15.5 1.7 6.6 6 1 1 7 7 7 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 EJS42066.1 - 2.6 7.9 50.9 0.17 11.7 1.7 6.9 7 0 0 7 7 7 0 Zinc knuckle ANAPC4_WD40 PF12894.7 EJS42067.1 - 2.7e-11 43.6 0.1 0.015 15.5 0.0 5.9 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJS42067.1 - 1.9e-06 28.5 14.3 1.9e-05 25.3 0.4 6.1 8 0 0 8 8 8 1 WD domain, G-beta repeat WD40_like PF17005.5 EJS42067.1 - 3.4e-05 23.3 0.7 0.00012 21.5 0.3 2.1 1 1 1 2 2 2 1 WD40-like domain Coatomer_WDAD PF04053.14 EJS42067.1 - 0.0029 16.7 0.7 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region Hira PF07569.11 EJS42067.1 - 0.0037 17.0 1.2 0.72 9.5 0.4 3.5 2 1 1 3 3 3 1 TUP1-like enhancer of split MRP-L46 PF11788.8 EJS42068.1 - 5.2e-37 127.2 0.2 8.6e-37 126.5 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 DUF3642 PF12182.8 EJS42068.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial lipoprotein AAA_23 PF13476.6 EJS42069.1 - 4.8e-38 131.7 2.2 4.8e-38 131.7 2.2 8.3 1 1 5 6 6 6 1 AAA domain Rad50_zn_hook PF04423.14 EJS42069.1 - 1e-17 63.7 4.3 1e-17 63.7 4.3 5.7 4 0 0 4 4 4 1 Rad50 zinc hook motif SMC_N PF02463.19 EJS42069.1 - 1.7e-07 30.9 0.1 1.7e-07 30.9 0.1 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EJS42069.1 - 2.7e-06 27.5 0.0 6.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EJS42069.1 - 1.3e-05 25.2 10.3 0.0012 18.7 0.1 5.9 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EJS42069.1 - 0.0008 19.1 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EJS42069.1 - 0.0068 16.8 1.6 0.055 13.8 0.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 EJS42069.1 - 0.032 12.9 0.0 0.032 12.9 0.0 7.6 2 1 6 9 9 9 0 AAA domain AAA_22 PF13401.6 EJS42069.1 - 0.24 11.7 0.0 0.24 11.7 0.0 4.7 5 1 0 5 5 5 0 AAA domain FCH PF00611.23 EJS42069.1 - 3.9 7.8 10.0 1.7 9.0 1.4 4.0 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain RNA_pol_I_A49 PF06870.12 EJS42070.1 - 4.9e-126 420.7 0.6 5.6e-126 420.5 0.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor tRNA-synt_1e PF01406.19 EJS42071.1 - 1.3e-146 487.7 0.5 1.3e-146 487.7 0.5 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EJS42071.1 - 6.9e-07 28.4 6.7 1e-05 24.5 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 EJS42071.1 - 0.00044 19.3 0.5 0.00094 18.2 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 EJS42071.1 - 0.00044 18.6 0.0 0.00044 18.6 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) RNA_pol_Rpb1_3 PF04983.18 EJS42071.1 - 0.028 14.3 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 Phage_int_SAM_5 PF13102.6 EJS42071.1 - 0.042 14.2 0.7 0.042 14.2 0.7 3.4 3 0 0 3 3 3 0 Phage integrase SAM-like domain Cir_N PF10197.9 EJS42072.1 - 8.3e-12 45.1 7.6 8.3e-12 45.1 7.6 1.9 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.8 EJS42072.1 - 3.5e-11 43.9 1.2 3.5e-11 43.9 1.2 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing factor DUF680 PF05079.12 EJS42072.1 - 0.0077 16.9 2.8 0.072 13.8 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF680) HlyD_2 PF12700.7 EJS42072.1 - 0.16 10.6 6.6 0.17 10.6 6.6 1.1 1 0 0 1 1 1 0 HlyD family secretion protein FapA PF03961.13 EJS42072.1 - 2.8 6.5 6.5 3.1 6.3 6.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SUI1 PF01253.22 EJS42073.1 - 4.5e-27 94.4 0.4 5.9e-27 94.0 0.4 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Bromo_TP_like PF17027.5 EJS42073.1 - 0.063 13.4 0.1 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 Histone-fold protein ANTH PF07651.16 EJS42074.1 - 4.7e-76 255.4 0.1 4.7e-76 255.4 0.1 3.0 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.17 EJS42074.1 - 2e-49 167.7 6.8 2e-49 167.7 6.8 5.2 4 2 2 6 6 6 1 I/LWEQ domain TFIIA PF03153.13 EJS42074.1 - 3.9 7.4 51.5 0.042 13.8 34.1 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Fe_hyd_lg_C PF02906.14 EJS42075.1 - 4.3e-49 167.4 0.0 6.1e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Peptidase_C1_2 PF03051.15 EJS42076.1 - 8e-179 595.0 0.5 9e-179 594.8 0.5 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EJS42076.1 - 4.8e-06 26.8 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease Ytp1 PF10355.9 EJS42077.1 - 5.6e-57 193.1 21.2 6.7e-55 186.3 21.2 2.5 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) Globin PF00042.22 EJS42078.1 - 2.8e-05 24.6 0.0 5.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Globin EXOSC1 PF10447.9 EJS42080.1 - 8.3e-42 142.2 1.3 9.2e-42 142.1 0.3 1.6 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 FSAP_sig_propep PF03032.15 EJS42080.1 - 1.6 8.9 5.9 2.7 8.1 5.9 1.4 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide CRAL_TRIO PF00650.20 EJS42081.1 - 6.3e-39 133.2 0.0 9.2e-39 132.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJS42081.1 - 1.7e-17 63.3 1.3 3.7e-17 62.3 1.3 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Elongin_A PF06881.11 EJS42082.1 - 1.4e-21 77.0 18.7 1.5e-16 60.8 0.7 3.1 2 1 1 3 3 3 2 RNA polymerase II transcription factor SIII (Elongin) subunit A FolB PF02152.18 EJS42082.1 - 0.15 12.7 0.8 1.6 9.3 0.0 2.6 3 0 0 3 3 3 0 Dihydroneopterin aldolase GST_C PF00043.25 EJS42083.1 - 2.3e-27 95.0 0.0 4.7e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EJS42083.1 - 9.7e-21 73.9 0.5 4.6e-20 71.8 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EJS42083.1 - 1.3e-09 38.3 0.0 3.3e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJS42083.1 - 1.1e-08 35.3 0.0 3.1e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EJS42083.1 - 1.7e-06 28.1 0.0 6.6e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EJS42083.1 - 0.0052 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_C54 PF03416.19 EJS42084.1 - 2.5e-81 273.1 0.0 3.2e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DUF2076 PF09849.9 EJS42084.1 - 0.027 14.5 0.3 0.049 13.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Ssu72 PF04722.13 EJS42085.1 - 7.9e-84 280.0 0.0 8.9e-84 279.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LAP2alpha PF11560.8 EJS42085.1 - 0.06 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha POP1 PF06978.11 EJS42086.1 - 5.1e-74 248.7 12.4 5.1e-74 248.7 12.4 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EJS42086.1 - 2.4e-31 107.9 1.7 6.6e-31 106.5 1.7 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain DASH_Dad4 PF08650.10 EJS42086.1 - 0.0095 15.9 0.1 0.032 14.2 0.1 1.9 1 0 0 1 1 1 1 DASH complex subunit Dad4 DUF4435 PF14491.6 EJS42086.1 - 0.028 14.3 1.0 0.1 12.4 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) Adenylsucc_synt PF00709.21 EJS42087.1 - 2e-177 590.3 0.0 2.3e-177 590.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Glyco_transf_22 PF03901.17 EJS42088.1 - 1.7e-100 337.2 35.5 2.2e-100 336.8 35.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Rap1-DNA-bind PF09197.10 EJS42089.1 - 1.5e-45 154.2 8.4 1.3e-44 151.2 0.5 3.2 4 0 0 4 4 4 2 Rap1, DNA-binding Rap1_C PF11626.8 EJS42089.1 - 2.8e-24 85.0 0.0 2.4e-23 82.0 0.0 2.3 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 EJS42089.1 - 6.5e-19 68.1 0.1 1.7e-17 63.6 0.0 3.0 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-binding PF00249.31 EJS42089.1 - 3.5e-13 49.5 0.8 1.7e-10 40.9 0.0 4.2 4 1 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 EJS42089.1 - 1.9e-09 37.6 0.5 5.1e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_6 PF13921.6 EJS42089.1 - 0.003 17.8 1.1 0.76 10.1 0.0 3.7 5 0 0 5 5 5 1 Myb-like DNA-binding domain SLIDE PF09111.10 EJS42089.1 - 0.21 11.7 0.7 0.82 9.7 0.0 2.4 3 0 0 3 3 3 0 SLIDE LIG3_BRCT PF16759.5 EJS42089.1 - 0.26 11.6 1.3 0.96 9.8 0.0 2.7 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain PAPA-1 PF04795.12 EJS42090.1 - 1.2e-19 70.9 4.4 1.2e-19 70.9 4.4 3.4 3 1 0 3 3 3 1 PAPA-1-like conserved region rve_3 PF13683.6 EJS42091.1 - 0.1 12.4 0.7 0.22 11.3 0.2 1.8 2 0 0 2 2 2 0 Integrase core domain Neugrin PF06413.11 EJS42092.1 - 1.4e-06 28.5 1.0 2.1e-06 27.9 0.3 1.6 1 1 0 1 1 1 1 Neugrin Sigma70_r4 PF04545.16 EJS42092.1 - 0.00031 20.2 0.0 0.00069 19.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 EJS42092.1 - 0.0019 18.1 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EJS42092.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 MarR family MRP-L20 PF12824.7 EJS42092.1 - 0.023 14.9 8.4 0.067 13.4 8.5 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 EJS42092.1 - 0.039 14.6 1.4 0.067 13.8 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 EJS42092.1 - 0.057 13.0 0.1 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 EJS42092.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_7 PF02796.15 EJS42092.1 - 0.074 13.1 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EJS42092.1 - 0.078 12.8 0.3 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain VID27 PF08553.10 EJS42093.1 - 2.6e-155 516.9 1.7 3.6e-155 516.4 1.7 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EJS42093.1 - 7.2e-44 149.7 1.9 7.2e-44 149.7 1.9 2.4 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 EJS42093.1 - 7.3e-31 106.7 0.3 3.1e-29 101.4 0.0 2.8 2 1 1 3 3 3 1 VID27 PH-like domain Pep1_7 PF17232.2 EJS42093.1 - 4.4 7.8 10.5 3.5 8.2 5.6 2.6 2 0 0 2 2 2 0 Elicitor peptide 1-7 DHHC PF01529.20 EJS42094.1 - 2.6e-32 111.7 14.0 2.6e-32 111.7 14.0 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF2481 PF10654.9 EJS42094.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) DUF5345 PF17280.2 EJS42094.1 - 7.2 6.7 7.3 0.39 10.7 1.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Syja_N PF02383.18 EJS42095.1 - 3.5e-76 256.6 0.2 3.5e-76 256.6 0.2 1.9 3 0 0 3 3 3 1 SacI homology domain CDC50 PF03381.15 EJS42096.1 - 1.3e-81 274.2 0.9 1.8e-81 273.8 0.9 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Na_Ca_ex PF01699.24 EJS42097.1 - 1.6e-19 70.3 31.6 5.1e-16 59.0 12.6 3.3 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 EJS42097.1 - 5.9e-13 49.3 6.5 5.9e-13 49.3 6.5 4.6 5 0 0 5 5 5 1 Inner membrane component domain Na_K-ATPase PF00287.18 EJS42097.1 - 0.0024 17.1 0.1 0.01 15.1 0.1 2.0 2 0 0 2 2 2 1 Sodium / potassium ATPase beta chain Hydrolase_4 PF12146.8 EJS42098.1 - 3e-15 56.1 0.0 9e-09 34.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EJS42098.1 - 1.4e-09 38.0 0.0 1.8e-05 24.5 0.1 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EJS42098.1 - 3.3e-05 23.5 0.0 0.00019 21.0 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 EJS42098.1 - 0.0014 18.4 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 EJS42098.1 - 0.0021 18.0 0.0 0.12 12.2 0.0 2.2 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 EJS42098.1 - 0.014 16.0 0.0 0.019 15.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EJS42098.1 - 0.13 12.1 0.0 16 5.2 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 EJS42098.1 - 0.18 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Sugar_tr PF00083.24 EJS42099.1 - 7.6e-114 381.0 32.8 9.1e-114 380.8 32.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS42099.1 - 9.6e-25 87.2 25.9 1.7e-21 76.6 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EJS42099.1 - 0.044 12.1 20.4 0.08 11.2 14.1 3.2 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SPC25 PF06703.11 EJS42099.1 - 0.046 13.5 0.1 0.046 13.5 0.1 3.2 5 0 0 5 5 5 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF932 PF06067.11 EJS42099.1 - 0.059 13.1 0.1 0.088 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF932) WD40 PF00400.32 EJS42100.1 - 1.5e-30 104.8 11.5 1.2e-06 29.1 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS42100.1 - 8.6e-18 64.4 0.2 0.024 14.9 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJS42100.1 - 1.4e-05 25.1 1.6 0.2 11.5 0.1 3.3 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EJS42100.1 - 0.00027 20.0 1.5 3.5 6.5 1.3 4.2 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PDT PF00800.18 EJS42101.1 - 6.5e-56 189.0 0.1 8.1e-56 188.7 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ATP11 PF06644.11 EJS42102.1 - 4.4e-93 312.0 3.1 5.4e-93 311.7 3.1 1.0 1 0 0 1 1 1 1 ATP11 protein Phage_int_SAM_5 PF13102.6 EJS42102.1 - 0.0036 17.6 3.2 0.01 16.1 3.2 1.8 1 1 0 1 1 1 1 Phage integrase SAM-like domain Myb_DNA-bind_5 PF13873.6 EJS42103.1 - 0.002 18.2 0.1 0.002 18.2 0.1 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EJS42103.1 - 0.075 14.0 0.2 0.22 12.5 0.0 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain TPR_8 PF13181.6 EJS42104.1 - 4.1e-07 29.7 7.9 0.014 15.5 0.6 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJS42104.1 - 6.5e-07 29.8 4.3 0.0041 17.6 0.1 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJS42104.1 - 7.2e-06 25.7 4.8 0.0041 17.1 0.3 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EJS42104.1 - 1.4e-05 25.5 2.9 0.7 10.9 0.1 5.8 4 2 2 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJS42104.1 - 2.1e-05 24.2 5.0 0.078 12.8 0.2 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EJS42104.1 - 0.0031 17.8 2.9 0.5 10.7 0.2 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EJS42104.1 - 0.0087 15.3 2.0 0.3 10.3 0.5 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EJS42104.1 - 0.011 16.1 1.0 0.12 12.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EJS42104.1 - 0.012 15.6 4.8 0.25 11.5 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 EJS42104.1 - 0.022 14.9 2.6 0.035 14.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 EJS42104.1 - 0.084 12.6 2.9 0.6 9.8 0.0 3.2 3 0 0 3 3 3 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 EJS42104.1 - 0.16 12.2 4.8 1.9 8.8 1.2 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 EJS42104.1 - 0.19 12.1 2.0 1.5 9.2 0.0 3.4 4 0 0 4 4 3 0 PPR repeat TPR_16 PF13432.6 EJS42104.1 - 0.38 11.4 5.5 5.7 7.7 0.2 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 EJS42106.1 - 4e-59 200.1 0.0 4.7e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42106.1 - 2.7e-29 102.3 0.0 3.6e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS42106.1 - 2.9e-05 23.5 0.0 7.2e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EJS42106.1 - 0.0023 17.9 0.1 0.007 16.3 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EJS42106.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EJS42106.1 - 0.018 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_S11 PF00411.19 EJS42107.1 - 0.00026 21.4 0.0 0.00039 20.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Bax1-I PF01027.20 EJS42108.1 - 4.7e-40 137.6 15.3 7.8e-40 136.9 15.3 1.3 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MerC PF03203.14 EJS42108.1 - 0.0014 19.1 7.0 0.0014 19.1 7.0 2.5 2 1 0 2 2 2 1 MerC mercury resistance protein BaxI_1 PF12811.7 EJS42108.1 - 0.0063 16.1 13.3 0.0064 16.1 10.2 1.9 2 0 0 2 2 2 1 Bax inhibitor 1 like DUF4064 PF13273.6 EJS42108.1 - 1.4 9.2 8.5 12 6.2 2.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4131 PF13567.6 EJS42108.1 - 1.6 8.4 8.2 2 8.0 1.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) MnhB PF04039.13 EJS42108.1 - 1.6 9.1 8.4 0.2 12.0 3.5 2.0 2 1 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Ras PF00071.22 EJS42109.1 - 1.8e-29 102.4 1.8 9.2e-25 87.1 1.7 2.6 2 1 0 2 2 2 2 Ras family Roc PF08477.13 EJS42109.1 - 4.3e-18 65.7 0.4 4.9e-12 46.1 0.2 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS42109.1 - 1.1e-06 28.2 2.1 2.2e-05 24.0 1.2 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EJS42109.1 - 0.0049 16.4 1.3 0.028 14.0 0.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EJS42109.1 - 0.0099 16.0 0.1 6.1 7.0 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase Pkinase PF00069.25 EJS42110.1 - 1.4e-62 211.4 0.1 1.4e-62 211.4 0.1 3.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42110.1 - 1.1e-49 169.1 0.0 1.1e-49 169.1 0.0 1.8 2 0 0 2 2 1 1 Protein tyrosine kinase PBD PF00786.28 EJS42110.1 - 2.3e-23 82.3 0.2 2.3e-23 82.3 0.2 2.9 2 1 0 2 2 1 1 P21-Rho-binding domain PH PF00169.29 EJS42110.1 - 5.7e-14 52.5 0.5 1.3e-13 51.3 0.5 1.7 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 EJS42110.1 - 6.9e-06 25.1 14.5 1.1e-05 24.5 0.0 2.8 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EJS42110.1 - 8.4e-06 25.3 0.0 8.4e-06 25.3 0.0 1.8 2 0 0 2 2 1 1 Kinase-like AAA_23 PF13476.6 EJS42110.1 - 0.0036 17.8 7.9 0.0073 16.8 7.9 1.5 1 0 0 1 1 1 1 AAA domain APH PF01636.23 EJS42110.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF4770 PF15994.5 EJS42110.1 - 3.2 8.0 29.4 0.1 12.9 22.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Exonuc_VII_L PF02601.15 EJS42110.1 - 5 6.6 19.8 11 5.4 19.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EJS42110.1 - 9.8 5.4 17.7 15 4.8 17.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DCB PF16213.5 EJS42111.1 - 3.3e-49 167.0 0.4 3.3e-49 167.0 0.4 3.4 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EJS42111.1 - 6.1e-31 107.5 2.9 6.1e-31 107.5 2.9 5.6 7 0 0 7 7 7 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 EJS42111.1 - 6.4e-13 47.8 6.6 7.5e-10 37.6 0.1 3.5 3 1 1 4 4 4 2 C-terminal region of Mon2 protein Pet20 PF08692.10 EJS42112.1 - 9.4e-35 120.1 0.3 3.1e-34 118.5 0.3 1.9 1 0 0 1 1 1 1 Mitochondrial protein Pet20 PalH PF08733.10 EJS42113.1 - 2.7e-84 283.0 18.4 3.4e-84 282.7 18.4 1.1 1 0 0 1 1 1 1 PalH/RIM21 NOA36 PF06524.12 EJS42113.1 - 2.7 7.2 8.2 4.7 6.4 8.2 1.3 1 0 0 1 1 1 0 NOA36 protein RabGAP-TBC PF00566.18 EJS42114.1 - 9.9e-45 152.8 5.8 1.5e-32 113.0 0.5 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DpnI_C PF17726.1 EJS42114.1 - 0.51 10.5 5.4 2.2 8.5 0.0 3.0 3 0 0 3 3 3 0 Dam-replacing HTH domain TruB_N PF01509.18 EJS42115.1 - 5.2e-41 140.5 0.7 4.2e-39 134.3 0.0 2.7 3 0 0 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EJS42115.1 - 0.0016 18.6 0.0 0.0061 16.7 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Mid1 PF12929.7 EJS42116.1 - 1.8e-129 432.7 22.5 2.1e-129 432.5 22.5 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EJS42116.1 - 0.0031 18.1 6.0 0.19 12.3 6.0 2.9 1 1 0 1 1 1 1 Fz domain Fer2_4 PF13510.6 EJS42116.1 - 0.052 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Cyclin_N PF00134.23 EJS42117.1 - 6.7e-24 84.1 0.0 1.3e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EJS42117.1 - 4.1e-08 33.7 0.0 8.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin Rcd1 PF04078.13 EJS42118.1 - 5.7e-113 376.5 4.0 6.7e-113 376.3 4.0 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Adaptin_N PF01602.20 EJS42119.1 - 2.9e-123 412.2 13.9 3.5e-123 411.9 13.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EJS42119.1 - 3.6e-48 163.5 1.1 9.2e-48 162.2 1.1 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EJS42119.1 - 3.1e-27 95.0 0.1 8.4e-27 93.6 0.1 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EJS42119.1 - 3.2e-13 49.9 0.5 4.5e-07 30.2 0.0 4.5 3 2 2 5 5 5 3 HEAT repeats Cnd1 PF12717.7 EJS42119.1 - 4.8e-06 26.7 12.9 0.0004 20.5 0.4 4.0 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EJS42119.1 - 0.00055 20.0 3.1 3.8 8.0 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat PAH PF02671.21 EJS42119.1 - 0.079 13.1 1.4 5.6 7.2 0.1 3.8 3 0 0 3 3 3 0 Paired amphipathic helix repeat HEAT_EZ PF13513.6 EJS42119.1 - 0.082 13.4 1.5 0.83 10.2 0.1 3.4 2 2 1 3 3 3 0 HEAT-like repeat TPR_20 PF14561.6 EJS42119.1 - 0.41 11.0 2.3 2.9 8.3 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Hist_deacetyl PF00850.19 EJS42120.1 - 1.8e-84 283.8 0.0 2.7e-84 283.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain AAA PF00004.29 EJS42121.1 - 5.3e-57 191.9 0.0 9.2e-46 155.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS42121.1 - 1.6e-09 37.4 0.0 2.5e-06 27.2 0.0 2.8 3 0 0 3 3 3 2 AAA+ lid domain AAA_2 PF07724.14 EJS42121.1 - 2.7e-05 24.3 0.0 0.00032 20.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EJS42121.1 - 0.00018 21.9 0.1 0.048 14.0 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EJS42121.1 - 0.00027 20.7 0.0 0.00093 19.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EJS42121.1 - 0.0005 19.3 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Vps4_C PF09336.10 EJS42121.1 - 0.0022 18.0 0.4 0.0095 15.9 0.1 2.3 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 EJS42121.1 - 0.0027 18.1 0.0 0.014 15.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 EJS42121.1 - 0.0051 16.8 0.0 0.021 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EJS42121.1 - 0.006 16.1 0.0 0.018 14.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 EJS42121.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 EJS42121.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EJS42121.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 EJS42121.1 - 0.018 15.3 0.0 0.097 12.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 EJS42121.1 - 0.021 15.4 0.0 0.17 12.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EJS42121.1 - 0.027 14.5 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EJS42121.1 - 0.029 13.8 0.1 0.054 12.9 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EJS42121.1 - 0.057 13.4 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EJS42121.1 - 0.088 12.4 0.1 0.44 10.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 EJS42121.1 - 0.2 11.1 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DnaJ PF00226.31 EJS42122.1 - 0.00044 20.3 0.1 0.00085 19.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 EJS42122.1 - 0.029 14.4 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Pam16 Osmo_CC PF08946.10 EJS42122.1 - 0.92 9.8 5.2 3.1 8.1 0.5 2.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Sugar_tr PF00083.24 EJS42123.1 - 2.4e-127 425.5 23.4 2.7e-127 425.4 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS42123.1 - 1.4e-25 90.0 24.1 1.4e-21 76.8 7.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OppC_N PF12911.7 EJS42123.1 - 8.4 6.5 13.1 0.14 12.2 0.4 3.4 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Pkinase PF00069.25 EJS42124.1 - 1.9e-70 237.2 0.0 5.9e-70 235.6 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 EJS42124.1 - 9.7e-34 115.6 3.2 3.6e-33 113.8 3.2 2.0 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 EJS42124.1 - 1.8e-33 115.9 0.0 5.7e-33 114.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS42124.1 - 2.4e-06 27.1 0.0 1.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Phage_B PF02304.15 EJS42124.1 - 0.025 14.9 0.4 0.079 13.3 0.4 1.8 1 0 0 1 1 1 0 Scaffold protein B HCO3_cotransp PF00955.21 EJS42124.1 - 0.34 9.7 0.7 0.7 8.7 0.7 1.4 1 0 0 1 1 1 0 HCO3- transporter family APH PF01636.23 EJS42124.1 - 0.48 10.3 0.0 0.48 10.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family AA_permease PF00324.21 EJS42125.1 - 1.9e-131 439.0 33.2 2.1e-131 438.8 33.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS42125.1 - 4e-31 108.3 32.1 5e-31 108.0 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease CCDC106 PF15794.5 EJS42125.1 - 0.018 14.7 0.8 0.032 14.0 0.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4781 PF16013.5 EJS42125.1 - 0.12 11.2 0.1 0.23 10.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Colicin_im PF03857.13 EJS42125.1 - 2 8.4 5.0 0.75 9.8 0.9 2.3 3 0 0 3 3 3 0 Colicin immunity protein Rad60-SLD PF11976.8 EJS42126.1 - 4e-19 68.2 0.5 6.4e-19 67.6 0.3 1.4 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EJS42126.1 - 7.5e-14 51.2 0.0 9.1e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.12 EJS42126.1 - 0.12 12.8 0.1 0.14 12.6 0.1 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Complex1_LYR_2 PF13233.6 EJS42127.1 - 5.3e-18 65.6 0.5 1.1e-17 64.5 0.5 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EJS42127.1 - 4e-12 46.0 0.1 9.2e-12 44.8 0.0 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EJS42127.1 - 0.035 14.7 0.0 0.056 14.1 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like ArnB_C PF18677.1 EJS42127.1 - 0.08 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Glutaredoxin PF00462.24 EJS42128.1 - 6.2e-15 55.2 0.0 9.8e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 EJS42128.1 - 0.007 16.4 0.3 0.045 13.8 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin domain La PF05383.17 EJS42130.1 - 2.7e-18 65.8 0.1 6e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 La domain Phage_Mu_F PF04233.14 EJS42130.1 - 1.4 9.7 7.5 3.5 8.4 7.5 1.7 1 1 0 1 1 1 0 Phage Mu protein F like protein Hexokinase_2 PF03727.16 EJS42131.1 - 6.7e-74 248.3 0.0 9.3e-74 247.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EJS42131.1 - 6.2e-70 235.2 0.0 8.8e-70 234.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Thioredoxin PF00085.20 EJS42132.1 - 2.8e-37 126.8 0.2 1.3e-19 70.1 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 EJS42132.1 - 6.5e-13 49.0 0.9 4e-12 46.4 0.4 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EJS42132.1 - 7.7e-05 22.9 0.1 0.68 10.3 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EJS42132.1 - 0.0015 18.7 0.1 0.7 10.1 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Calsequestrin PF01216.17 EJS42132.1 - 0.0046 16.1 0.7 0.007 15.5 0.1 1.5 2 0 0 2 2 2 1 Calsequestrin Pyr_excise PF03013.14 EJS42132.1 - 0.06 13.3 0.2 0.78 9.7 0.0 2.4 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase FKBP_C PF00254.28 EJS42133.1 - 1.2e-34 118.5 0.0 1.6e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Zn_clus PF00172.18 EJS42134.1 - 1.2e-05 25.3 6.3 2.5e-05 24.3 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LT-IIB PF06453.11 EJS42135.1 - 0.051 13.5 1.3 0.054 13.4 0.9 1.2 1 1 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Ost5 PF05251.12 EJS42135.1 - 0.23 11.7 6.9 0.33 11.3 6.9 1.3 1 1 0 1 1 1 0 Oligosaccharyltransferase subunit 5 Pmp3 PF01679.17 EJS42136.1 - 1e-18 67.2 7.9 1.2e-18 67.0 7.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RPAP1_C PF08620.10 EJS42137.1 - 5.4e-29 100.1 0.1 1.1e-28 99.2 0.1 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EJS42137.1 - 5.4e-16 58.1 2.8 5.4e-16 58.1 2.8 2.0 2 0 0 2 2 2 1 RPAP1-like, N-terminal Arena_ncap_C PF17290.2 EJS42138.1 - 0.013 14.9 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain UCR_14kD PF02271.16 EJS42139.1 - 2.5e-39 133.3 0.1 2.9e-39 133.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Kre28 PF17097.5 EJS42140.1 - 4.9e-125 417.3 34.3 5.5e-125 417.1 34.3 1.0 1 0 0 1 1 1 1 Spindle pole body component DUF1216 PF06746.11 EJS42140.1 - 0.098 12.7 12.8 0.055 13.5 4.7 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1216) HALZ PF02183.18 EJS42140.1 - 0.61 10.4 9.4 0.46 10.8 4.5 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper Occludin_ELL PF07303.13 EJS42140.1 - 1.1 10.1 9.9 6.6 7.5 1.9 3.7 2 1 1 3 3 3 0 Occludin homology domain DUF349 PF03993.12 EJS42140.1 - 2.1 8.7 11.6 3.7 7.9 1.2 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DivIC PF04977.15 EJS42140.1 - 7.9 6.3 12.3 18 5.2 4.6 3.1 2 1 0 2 2 2 0 Septum formation initiator Rpn9_C PF18261.1 EJS42141.1 - 9.8e-18 63.4 1.7 2.1e-17 62.4 1.7 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix PCI PF01399.27 EJS42141.1 - 1.4e-14 54.4 0.7 6.1e-14 52.4 0.7 2.1 1 0 0 1 1 1 1 PCI domain MRP-L46 PF11788.8 EJS42141.1 - 0.093 13.5 0.6 0.59 10.9 0.0 2.2 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 Foie-gras_1 PF11817.8 EJS42141.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 eIF3g PF12353.8 EJS42142.1 - 2.7e-37 128.0 0.5 3.9e-37 127.4 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EJS42142.1 - 3.1e-11 42.9 0.0 5.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EJS42142.1 - 0.039 14.2 1.7 0.28 11.4 0.0 2.3 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter zf-CCCH_7 PF18586.1 EJS42142.1 - 0.04 14.2 1.3 0.19 12.1 0.1 2.5 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 M16C_assoc PF08367.11 EJS42143.1 - 1.2e-71 240.8 0.1 2.2e-71 239.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EJS42143.1 - 3.7e-31 108.5 0.1 4.4e-19 69.2 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EJS42143.1 - 4.9e-06 26.6 0.0 1.9e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RRM_1 PF00076.22 EJS42144.1 - 8.5e-30 102.4 0.1 1.4e-17 63.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EJS42144.1 - 0.0069 16.2 0.0 0.019 14.8 0.0 1.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EJS42144.1 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJS42144.1 - 0.049 13.8 0.1 0.43 10.7 0.1 2.2 1 1 0 1 1 1 0 RNA recognition motif SPX PF03105.19 EJS42144.1 - 1.3 8.8 3.9 1.6 8.5 3.9 1.1 1 0 0 1 1 1 0 SPX domain PIG-S PF10510.9 EJS42145.1 - 7.1e-133 444.1 5.0 8.2e-133 443.9 5.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein LCM PF04072.14 EJS42146.1 - 5.4e-30 104.7 0.0 6.6e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Metallophos PF00149.28 EJS42147.1 - 1.4e-34 120.4 0.1 2.3e-34 119.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EJS42147.1 - 8.7e-19 67.7 0.4 1.8e-18 66.7 0.4 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PIG-P PF08510.12 EJS42148.1 - 1.7e-31 108.7 1.9 1.9e-31 108.5 1.9 1.0 1 0 0 1 1 1 1 PIG-P V_ATPase_I PF01496.19 EJS42148.1 - 0.0022 16.0 0.0 0.0023 16.0 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family LRS4 PF10422.9 EJS42149.1 - 3.7e-58 197.0 17.7 3.7e-58 197.0 17.7 2.0 2 0 0 2 2 2 1 Monopolin complex subunit LRS4 DOT1 PF08123.13 EJS42150.1 - 4.2e-92 307.3 1.1 6.9e-92 306.6 1.1 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 EJS42150.1 - 0.01 15.2 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RTT107_BRCT_6 PF16771.5 EJS42150.1 - 0.11 12.6 3.0 0.2 11.8 0.8 2.3 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Pribosyltran PF00156.27 EJS42151.1 - 1.1e-14 54.2 0.0 1.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EJS42151.1 - 0.0021 17.5 0.0 0.0035 16.8 0.0 1.5 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Med13_N PF11597.8 EJS42152.1 - 3.7e-60 204.0 0.6 3.7e-60 204.0 0.6 2.1 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 EJS42152.1 - 8.8e-21 74.5 9.6 7.3e-15 55.1 0.1 3.8 2 2 1 3 3 3 2 Mediator complex subunit 13 C-terminal domain Phage_Gp15 PF06854.11 EJS42152.1 - 0.019 14.9 1.2 0.092 12.7 0.6 2.4 2 0 0 2 2 2 0 Bacteriophage Gp15 protein ZZ PF00569.17 EJS42153.1 - 5.3e-18 64.5 8.1 9.1e-18 63.8 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 EJS42153.1 - 6.2e-10 39.1 0.3 1.9e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 EJS42153.1 - 6.1e-08 32.9 1.1 7.5e-07 29.4 0.0 2.8 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 EJS42153.1 - 4.2e-05 23.7 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3530 PF12048.8 EJS42153.1 - 0.1 12.0 0.2 6.5 6.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) U3_assoc_6 PF08640.11 EJS42154.1 - 2e-32 111.1 3.8 3e-31 107.3 0.6 3.0 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 EJS42154.1 - 0.00012 21.3 3.3 0.0043 16.2 0.6 2.7 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EJS42154.1 - 0.0019 18.9 0.0 1.5 9.9 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EJS42154.1 - 0.0094 16.3 1.4 4.2 8.0 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2250 PF10007.9 EJS42154.1 - 0.072 13.2 2.0 3.3 7.9 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) Suf PF05843.14 EJS42154.1 - 0.11 12.5 10.1 0.055 13.5 2.3 3.6 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) HAT PF02184.16 EJS42154.1 - 0.12 12.4 0.3 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat Homeodomain PF00046.29 EJS42155.1 - 2e-17 62.8 1.0 3.9e-17 61.8 1.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EJS42155.1 - 0.0018 18.2 0.2 0.015 15.2 0.1 2.3 2 0 0 2 2 2 1 Homeobox KN domain DUF5086 PF16985.5 EJS42155.1 - 0.046 13.6 0.3 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5086) Keratin PF02422.16 EJS42155.1 - 0.07 12.8 3.9 0.75 9.5 0.8 2.4 2 0 0 2 2 2 0 Keratin Metallophos PF00149.28 EJS42156.1 - 3.1e-08 34.4 0.2 7.9e-08 33.0 0.2 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_S49_N PF08496.10 EJS42156.1 - 1.9 8.5 5.4 20 5.2 0.3 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AhpC-TSA PF00578.21 EJS42157.1 - 5.6e-33 113.5 0.0 3.3e-32 111.0 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EJS42157.1 - 4.1e-17 62.2 0.0 8.8e-17 61.2 0.0 1.5 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 EJS42157.1 - 1.2e-08 34.6 0.2 2.2e-08 33.8 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EJS42157.1 - 0.04 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 SCO1/SenC Guanylate_kin PF00625.21 EJS42158.1 - 1.3e-69 233.5 0.0 1.5e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 EJS42158.1 - 1.2e-05 25.5 0.0 3.8e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJS42158.1 - 1.4e-05 25.5 0.0 1.8e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EJS42158.1 - 4.4e-05 23.3 0.1 0.0033 17.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJS42158.1 - 0.00012 22.6 0.2 0.00047 20.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EJS42158.1 - 0.00015 22.1 0.0 0.00054 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EJS42158.1 - 0.00031 20.8 0.0 0.00042 20.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EJS42158.1 - 0.00057 19.7 0.0 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EJS42158.1 - 0.0007 20.1 0.0 0.0011 19.5 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 EJS42158.1 - 0.0013 19.0 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EJS42158.1 - 0.0017 18.1 1.4 0.018 14.8 0.1 2.4 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.6 EJS42158.1 - 0.0017 18.4 0.0 0.0036 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EJS42158.1 - 0.0028 18.0 0.0 0.0056 17.0 0.0 1.7 1 1 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 EJS42158.1 - 0.0042 17.0 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_7 PF12775.7 EJS42158.1 - 0.0049 16.4 0.0 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 EJS42158.1 - 0.0055 16.6 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 EJS42158.1 - 0.0084 16.5 0.0 0.018 15.5 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EJS42158.1 - 0.016 15.5 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EJS42158.1 - 0.017 15.0 0.1 0.03 14.3 0.1 1.4 1 1 0 1 1 1 0 Rad17 P-loop domain Tfb5 PF06331.12 EJS42158.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 DUF2075 PF09848.9 EJS42158.1 - 0.021 14.1 0.0 0.024 13.9 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EJS42158.1 - 0.021 14.7 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 EJS42158.1 - 0.023 13.8 0.2 0.093 11.8 0.1 1.9 1 1 1 2 2 2 0 Type II/IV secretion system protein KRTDAP PF15200.6 EJS42158.1 - 0.029 14.1 0.1 0.055 13.2 0.1 1.5 1 0 0 1 1 1 0 Keratinocyte differentiation-associated ATPase_2 PF01637.18 EJS42158.1 - 0.048 13.6 0.1 0.082 12.8 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 EJS42158.1 - 0.049 13.2 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EJS42158.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.7 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.15 EJS42158.1 - 0.07 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_5 PF07728.14 EJS42158.1 - 0.074 13.1 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EJS42158.1 - 0.085 13.3 0.3 0.27 11.7 0.0 1.9 2 1 1 3 3 2 0 AAA domain Parvo_NS1 PF01057.17 EJS42158.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 dNK PF01712.19 EJS42158.1 - 0.1 12.5 0.2 2.2 8.1 0.0 2.6 2 1 0 2 2 2 0 Deoxynucleoside kinase AAA_23 PF13476.6 EJS42158.1 - 0.18 12.3 2.8 0.4 11.1 2.8 2.0 1 1 0 1 1 1 0 AAA domain Na_H_Exchanger PF00999.21 EJS42159.1 - 4.5e-70 236.4 36.0 6.1e-70 235.9 36.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Wzy_C PF04932.15 EJS42159.1 - 4.3 7.0 0.0 4.3 7.0 0.0 3.7 3 2 0 3 3 3 0 O-Antigen ligase Myc_target_1 PF15179.6 EJS42159.1 - 5.7 6.8 9.8 0.092 12.6 0.7 2.4 3 0 0 3 3 3 0 Myc target protein 1 HECT PF00632.25 EJS42160.1 - 1.6e-89 300.4 2.4 2.1e-89 300.1 0.0 2.5 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 EJS42160.1 - 2.8e-58 198.1 7.3 3.7e-57 194.4 1.2 3.7 3 1 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 EJS42160.1 - 2.4e-51 174.9 6.1 1.7e-50 172.1 0.0 4.7 5 0 0 5 5 5 1 Domain of Unknown Function (DUF913) UBM PF14377.6 EJS42160.1 - 3.3e-13 48.6 4.0 2.2e-08 33.2 0.2 2.8 2 0 0 2 2 2 2 Ubiquitin binding region LRR_5 PF13306.6 EJS42160.1 - 8.9 6.3 9.1 0.68 9.9 0.3 3.5 4 0 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) MSC PF09402.10 EJS42161.1 - 1.2e-89 301.1 4.8 1.2e-89 301.1 4.8 2.3 2 1 0 2 2 2 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EJS42161.1 - 4.8e-16 58.2 0.3 4.8e-16 58.2 0.3 2.6 2 0 0 2 2 2 1 HeH/LEM domain Thymopoietin PF08198.11 EJS42161.1 - 0.059 13.0 0.2 0.15 11.7 0.2 1.7 1 0 0 1 1 1 0 Thymopoietin protein HSM3_N PF18795.1 EJS42161.1 - 0.068 12.6 2.0 0.14 11.6 2.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain MAT1 PF06391.13 EJS42162.1 - 4.5e-65 219.3 26.7 6e-65 218.9 26.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EJS42162.1 - 3.1e-27 94.2 8.0 3.1e-27 94.2 8.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJS42162.1 - 0.00049 20.4 6.5 0.00088 19.6 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EJS42162.1 - 0.00051 19.8 6.2 0.001 18.9 6.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJS42162.1 - 0.00094 19.0 6.6 0.002 17.9 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJS42162.1 - 0.017 15.0 6.5 0.07 13.0 6.6 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJS42162.1 - 0.018 15.1 6.6 0.036 14.1 6.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EJS42162.1 - 0.073 13.0 9.1 1 9.4 9.3 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Perilipin PF03036.16 EJS42162.1 - 0.082 11.9 5.5 0.11 11.5 5.5 1.1 1 0 0 1 1 1 0 Perilipin family FliS PF02561.14 EJS42162.1 - 0.14 12.5 8.0 0.088 13.1 0.9 2.3 1 1 1 2 2 2 0 Flagellar protein FliS zf-RING_4 PF14570.6 EJS42162.1 - 0.55 10.1 9.0 7 6.5 9.0 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Exonuc_VII_L PF02601.15 EJS42162.1 - 0.57 9.7 4.9 0.76 9.3 4.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prok-RING_4 PF14447.6 EJS42162.1 - 1.5 8.7 9.1 4.2 7.3 3.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Tweety PF04906.13 EJS42162.1 - 3.8 6.1 4.4 1.2 7.8 0.5 1.8 1 1 1 2 2 2 0 Tweety MFA1_2 PF17317.2 EJS42163.1 - 1.2e-20 72.9 0.2 1.4e-20 72.7 0.2 1.1 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 LOR PF04525.12 EJS42163.1 - 0.026 14.1 0.0 0.026 14.1 0.0 1.0 1 0 0 1 1 1 0 LURP-one-related MRP-L28 PF09812.9 EJS42165.1 - 2.6e-37 128.4 2.6 3.2e-37 128.2 2.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF4220 PF13968.6 EJS42165.1 - 0.042 13.2 0.2 0.046 13.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) zf-C2H2_4 PF13894.6 EJS42166.1 - 1.6e-05 25.3 10.2 0.011 16.6 1.0 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EJS42166.1 - 0.00054 20.3 12.3 0.0011 19.3 2.5 3.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJS42166.1 - 0.05 14.1 1.1 0.05 14.1 1.1 3.6 4 0 0 4 4 4 0 Zinc-finger double domain CpXC PF14353.6 EJS42166.1 - 0.12 12.4 0.6 3 7.9 0.0 2.9 3 0 0 3 3 3 0 CpXC protein zf-C2HE PF16278.5 EJS42166.1 - 0.24 11.9 2.2 3.5 8.1 0.0 3.2 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger PriA_CRR PF18319.1 EJS42166.1 - 0.63 10.1 0.1 0.63 10.1 0.1 2.6 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain DUF3020 PF11223.8 EJS42167.1 - 1.6e-16 60.6 29.8 4.5e-16 59.1 7.8 7.3 8 0 0 8 8 8 2 Protein of unknown function (DUF3020) Methyltransf_11 PF08241.12 EJS42168.1 - 0.086 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PAS_4 PF08448.10 EJS42168.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.9 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.25 EJS42169.1 - 1.3e-60 205.0 0.0 2e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42169.1 - 6.3e-28 97.8 0.0 1.9e-27 96.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS42169.1 - 7.8e-08 32.0 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJS42169.1 - 0.0028 17.6 0.3 0.0048 16.8 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 EJS42169.1 - 0.011 15.3 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 FTA2 PF13095.6 EJS42169.1 - 0.015 15.0 0.6 3.1 7.4 0.2 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EJS42169.1 - 0.05 13.2 0.3 0.15 11.7 0.3 1.8 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 EJS42169.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EJS42169.1 - 0.16 10.7 2.0 0.22 10.2 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase SNARE PF05739.19 EJS42170.1 - 3.5e-05 23.7 0.4 3.5e-05 23.7 0.4 2.0 2 0 0 2 2 1 1 SNARE domain Sec3_C PF09763.9 EJS42170.1 - 0.00057 18.4 0.4 0.00089 17.8 0.4 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec3 Syntaxin-6_N PF09177.11 EJS42170.1 - 0.00077 20.0 5.3 0.00077 20.0 5.3 2.8 2 1 1 3 3 3 1 Syntaxin 6, N-terminal Use1 PF09753.9 EJS42170.1 - 0.0012 18.7 5.5 0.0019 18.0 5.5 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 NBD_C PF17042.5 EJS42170.1 - 0.023 15.2 1.6 0.044 14.3 1.6 1.4 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain DUF4848 PF16140.5 EJS42170.1 - 0.026 14.1 0.4 0.061 12.9 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4848) FokI_C PF02980.16 EJS42170.1 - 0.038 14.0 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain DUF2207 PF09972.9 EJS42170.1 - 0.055 12.2 2.1 0.27 10.0 0.0 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) ATG16 PF08614.11 EJS42170.1 - 0.091 13.0 7.1 0.031 14.5 3.5 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GCP_C_terminal PF04130.13 EJS42170.1 - 0.091 12.2 2.4 0.1 12.0 2.2 1.3 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal CHDCT2 PF08074.11 EJS42170.1 - 0.11 12.6 3.8 2.8 8.1 0.1 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF745 PF05335.13 EJS42170.1 - 0.12 12.0 4.4 3.5 7.3 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF1043 PF06295.12 EJS42170.1 - 0.14 12.2 6.9 0.1 12.6 0.5 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1043) Sec20 PF03908.13 EJS42170.1 - 0.18 11.8 1.3 0.59 10.1 0.0 2.3 2 1 2 4 4 4 0 Sec20 CLZ PF16526.5 EJS42170.1 - 0.49 10.8 10.0 0.3 11.5 0.3 3.5 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pex19 PF04614.12 EJS42170.1 - 0.49 10.1 11.5 0.32 10.7 0.2 2.2 1 1 0 2 2 2 0 Pex19 protein family RmuC PF02646.16 EJS42170.1 - 0.55 9.3 7.8 0.9 8.6 0.3 2.7 2 1 1 3 3 3 0 RmuC family Allexi_40kDa PF05549.11 EJS42170.1 - 0.84 9.1 7.9 0.47 9.9 3.4 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF2951 PF11166.8 EJS42170.1 - 0.85 9.9 12.8 0.78 10.0 4.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2951) FAM184 PF15665.5 EJS42170.1 - 1.1 9.0 14.4 7.1 6.3 14.4 2.6 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B HrpB2 PF09487.10 EJS42170.1 - 1.3 9.5 5.5 9.9 6.6 0.0 3.3 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB2) Hrs_helical PF12210.8 EJS42170.1 - 1.6 9.3 13.4 2.9 8.5 5.7 3.0 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate SpmSyn_N PF17950.1 EJS42170.1 - 1.7 8.9 4.5 10 6.4 0.1 3.1 3 1 0 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal CR6_interact PF10147.9 EJS42170.1 - 2.7 7.7 6.2 1.2 8.9 3.5 1.7 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF4407 PF14362.6 EJS42170.1 - 3.2 7.0 6.6 5.7 6.2 6.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PMC2NT PF08066.12 EJS42170.1 - 3.3 8.5 8.5 13 6.5 3.9 2.7 2 1 0 2 2 2 0 PMC2NT (NUC016) domain DUF16 PF01519.16 EJS42170.1 - 4.5 7.8 16.6 31 5.1 7.8 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Spc7 PF08317.11 EJS42170.1 - 4.7 6.0 13.4 1.4 7.7 5.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Phage_GPO PF05929.11 EJS42170.1 - 5.6 6.5 8.3 0.54 9.8 3.4 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Spectrin PF00435.21 EJS42170.1 - 6 7.4 9.5 3.2 8.3 2.9 2.4 2 1 0 2 2 2 0 Spectrin repeat TMPIT PF07851.13 EJS42170.1 - 6.4 5.9 5.6 9.7 5.3 1.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein Fez1 PF06818.15 EJS42170.1 - 9.4 6.6 11.4 5.5 7.4 0.6 2.3 1 1 0 2 2 2 0 Fez1 Mito_carr PF00153.27 EJS42171.1 - 1.7e-11 43.9 0.0 0.0009 19.1 0.0 3.7 3 1 0 3 3 3 2 Mitochondrial carrier protein TRAPP PF04051.16 EJS42172.1 - 9.5e-48 161.6 0.0 1.3e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3399 PF11879.8 EJS42173.1 - 4.9 7.5 0.0 4.9 7.5 0.0 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF3399) Rpr2 PF04032.16 EJS42174.1 - 4.3e-11 42.9 0.6 4.3e-11 42.9 0.6 2.1 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pex24p PF06398.11 EJS42175.1 - 1.2e-86 291.0 11.1 1.5e-86 290.7 11.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Alk_phosphatase PF00245.20 EJS42177.1 - 2.1e-148 494.7 0.5 2.5e-148 494.5 0.5 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EJS42177.1 - 1.7e-05 24.3 0.7 4.4e-05 23.0 0.0 2.0 3 0 0 3 3 3 1 Metalloenzyme superfamily cwf21 PF08312.12 EJS42178.1 - 4.6e-15 55.5 5.1 4.6e-15 55.5 5.1 1.6 2 0 0 2 2 2 1 cwf21 domain Trans_reg_C PF00486.28 EJS42178.1 - 0.0055 16.8 0.2 0.11 12.6 0.1 2.2 1 1 1 2 2 2 1 Transcriptional regulatory protein, C terminal TLE_N PF03920.15 EJS42178.1 - 0.14 12.2 5.9 0.04 14.0 2.3 1.8 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Vps52 PF04129.12 EJS42179.1 - 1.2e-196 654.4 20.0 1.6e-196 654.0 20.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Bacillus_HBL PF05791.11 EJS42179.1 - 0.93 9.3 13.5 0.043 13.7 3.1 2.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) YL1 PF05764.13 EJS42180.1 - 1.3e-48 166.3 43.8 1.3e-48 166.3 43.8 2.9 2 2 1 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 EJS42180.1 - 5.6e-14 51.6 0.4 1.1e-13 50.7 0.4 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Snf7 PF03357.21 EJS42181.1 - 4.9e-40 137.0 25.9 5.8e-40 136.7 25.9 1.1 1 0 0 1 1 1 1 Snf7 SKA1 PF07160.12 EJS42181.1 - 0.0012 18.7 19.2 0.0042 17.0 18.8 1.9 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 Fmp27_WPPW PF10359.9 EJS42181.1 - 0.0014 17.5 14.0 0.0018 17.3 13.8 1.3 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain YlqD PF11068.8 EJS42181.1 - 0.012 16.0 17.4 0.012 16.0 17.4 2.2 1 1 1 2 2 2 0 YlqD protein TMF_TATA_bd PF12325.8 EJS42181.1 - 0.044 14.0 16.5 1.9 8.7 15.8 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TrfA PF07042.11 EJS42181.1 - 0.047 12.7 0.9 0.065 12.3 0.9 1.3 1 0 0 1 1 1 0 TrfA protein AceK PF06315.11 EJS42181.1 - 0.07 11.6 2.9 0.083 11.4 2.9 1.0 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Exonuc_VII_L PF02601.15 EJS42181.1 - 0.11 12.1 12.8 0.15 11.6 12.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 EJS42181.1 - 0.39 10.9 19.4 0.04 14.2 10.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Sec34 PF04136.15 EJS42181.1 - 0.71 9.7 16.3 0.18 11.7 8.7 2.4 1 1 2 3 3 3 0 Sec34-like family V_ATPase_I PF01496.19 EJS42181.1 - 0.89 7.4 11.7 1 7.2 11.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S46 PF10459.9 EJS42181.1 - 1 8.0 11.9 1.2 7.7 11.9 1.1 1 0 0 1 1 1 0 Peptidase S46 BLOC1_2 PF10046.9 EJS42181.1 - 1.1 9.6 20.8 1 9.7 4.4 3.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC-167 PF15188.6 EJS42181.1 - 2.2 8.7 7.3 5.1 7.5 6.5 2.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.12 EJS42181.1 - 2.7 8.0 16.0 0.49 10.4 7.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EJS42181.1 - 4.3 7.8 10.2 3.5 8.1 0.2 3.8 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) RasGAP_C PF03836.15 EJS42181.1 - 4.4 7.4 18.0 1.2 9.3 12.0 2.3 1 1 1 2 2 2 0 RasGAP C-terminus YabA PF06156.13 EJS42181.1 - 5.8 7.6 16.2 47 4.7 11.0 3.0 1 1 1 2 2 2 0 Initiation control protein YabA DHBP_synthase PF00926.19 EJS42182.1 - 7.2e-84 280.1 0.1 8.1e-84 279.9 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase WD40 PF00400.32 EJS42183.1 - 0.00063 20.5 0.1 0.0068 17.2 0.1 2.7 1 1 1 2 2 2 1 WD domain, G-beta repeat SLD5_C PF16922.5 EJS42184.1 - 1.1e-22 80.0 0.0 2.2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EJS42184.1 - 1.2e-08 35.3 1.2 7.3e-08 32.8 0.7 2.2 2 0 0 2 2 2 1 GINS complex protein Pkinase PF00069.25 EJS42185.1 - 2.2e-62 210.9 0.0 3.3e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42185.1 - 1.3e-29 103.3 0.0 2.3e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS42185.1 - 9.3e-07 28.4 0.0 2.3e-05 23.9 0.0 2.7 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EJS42185.1 - 1.4e-05 24.8 0.1 0.015 14.9 0.0 2.6 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EJS42185.1 - 0.00013 20.9 0.1 0.00056 18.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EJS42185.1 - 0.003 17.0 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJS42185.1 - 0.05 13.5 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3409 PF11889.8 EJS42185.1 - 0.095 12.6 5.3 3.3 7.7 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3409) HlyIII PF03006.20 EJS42186.1 - 8.9e-58 195.6 25.1 1.1e-57 195.4 25.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4118 PF13493.6 EJS42186.1 - 0.019 14.7 0.2 0.019 14.7 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4118) CPL PF08144.11 EJS42189.1 - 6.4e-49 166.0 3.5 1.2e-46 158.6 0.0 4.7 5 1 0 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 EJS42189.1 - 6.6e-06 25.5 5.7 0.13 12.0 0.0 6.3 7 0 0 7 7 7 1 Pumilio-family RNA binding repeat SAC3 PF12209.8 EJS42189.1 - 0.093 12.9 1.3 5.9 7.2 0.0 4.2 3 1 1 4 4 4 0 Leucine permease transcriptional regulator helical domain DUF3343 PF11823.8 EJS42189.1 - 0.16 11.4 0.0 0.96 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Sugar_tr PF00083.24 EJS42190.1 - 1.7e-134 449.1 31.5 1.9e-134 448.9 31.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS42190.1 - 8.4e-31 107.2 34.1 1.1e-29 103.5 25.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EJS42190.1 - 4.7e-05 22.0 1.2 4.7e-05 22.0 1.2 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector Herpes_teg_N PF04843.12 EJS42190.1 - 0.096 12.4 0.0 0.41 10.3 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region PIG-P PF08510.12 EJS42190.1 - 0.12 12.3 0.1 3.1 7.7 0.1 2.7 1 1 0 1 1 1 0 PIG-P Sec20 PF03908.13 EJS42191.1 - 4.9e-34 116.1 0.5 1.1e-33 115.0 0.5 1.6 1 0 0 1 1 1 1 Sec20 FHA PF00498.26 EJS42192.1 - 1.3e-06 28.7 0.0 5.6e-06 26.6 0.0 2.1 1 0 0 1 1 1 1 FHA domain S-AdoMet_synt_C PF02773.16 EJS42193.1 - 1.1e-64 216.6 0.1 1.8e-64 215.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 EJS42193.1 - 5.6e-46 155.3 1.5 9.7e-46 154.5 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 EJS42193.1 - 5.2e-45 152.6 0.0 1.1e-44 151.5 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 EJS42193.1 - 0.024 13.4 0.1 0.14 10.9 0.1 1.9 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) PAP2 PF01569.21 EJS42194.1 - 1.5e-24 86.3 2.0 1.5e-24 86.3 2.0 1.8 3 0 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 EJS42194.1 - 8.9e-05 22.3 5.6 0.00026 20.8 4.5 2.2 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EJS42194.1 - 0.0049 17.4 3.9 0.0049 17.4 3.9 2.5 3 0 0 3 3 3 1 PAP2 superfamily C-terminal LtrA PF06772.11 EJS42194.1 - 0.0052 16.1 0.1 0.41 9.8 0.5 2.2 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) PSP1 PF04468.12 EJS42195.1 - 4.5e-42 142.2 0.8 4.5e-42 142.2 0.8 2.2 2 1 0 2 2 2 1 PSP1 C-terminal conserved region Sugar_tr PF00083.24 EJS42196.1 - 2.8e-92 309.9 28.9 2.2e-51 175.1 4.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EJS42196.1 - 2.5e-23 82.6 32.1 4.8e-19 68.5 10.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 EJS42196.1 - 0.32 11.6 7.3 0.34 11.5 4.0 2.6 2 0 0 2 2 2 0 Phage holin family 2 BAR PF03114.18 EJS42197.1 - 4.7e-67 226.1 7.7 5.8e-67 225.8 7.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EJS42197.1 - 8e-15 54.2 0.0 1.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJS42197.1 - 7.3e-12 45.0 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJS42197.1 - 3.9e-07 29.7 0.0 7.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Spectrin PF00435.21 EJS42197.1 - 1 9.9 6.2 6.2 7.4 1.1 2.5 2 0 0 2 2 2 0 Spectrin repeat DUF755 PF05501.11 EJS42197.1 - 1.8 8.9 7.9 0.15 12.3 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) RhoGAP PF00620.27 EJS42198.1 - 2.4e-31 108.6 0.7 2.5e-30 105.3 0.2 2.7 2 1 0 2 2 2 1 RhoGAP domain ThiF PF00899.21 EJS42199.1 - 3.5e-73 246.0 0.0 4.6e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EJS42199.1 - 7.1e-08 32.7 9.9 1.6e-05 25.0 1.4 2.7 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 EJS42199.1 - 0.015 15.4 0.0 0.044 13.8 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 EJS42199.1 - 0.021 15.4 0.2 0.062 13.9 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 EJS42199.1 - 0.031 14.7 0.0 0.26 11.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 EJS42199.1 - 0.092 11.9 0.1 0.49 9.5 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TGT PF01702.18 EJS42199.1 - 0.11 11.7 0.2 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase Utp13 PF08625.11 EJS42199.1 - 0.12 12.3 0.2 0.26 11.2 0.2 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Hormone_2 PF00123.20 EJS42199.1 - 0.16 11.9 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Peptide hormone UBA2_C PF16195.5 EJS42199.1 - 0.27 11.9 3.4 0.63 10.8 3.4 1.5 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus TFIID-18kDa PF02269.16 EJS42200.1 - 5.5e-38 128.9 0.5 6.1e-37 125.5 0.1 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Synaptobrevin PF00957.21 EJS42200.1 - 0.22 11.3 4.6 0.083 12.7 1.5 1.9 2 0 0 2 2 2 0 Synaptobrevin She9_MDM33 PF05546.11 EJS42201.1 - 1.5e-87 292.5 12.7 1.5e-87 292.5 12.7 2.2 2 0 0 2 2 2 2 She9 / Mdm33 family PsbH PF00737.20 EJS42201.1 - 0.15 11.8 0.6 0.32 10.8 0.6 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein AAA PF00004.29 EJS42202.1 - 2.1e-46 157.6 0.1 9.8e-46 155.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EJS42202.1 - 9.2e-09 35.1 0.1 5.8e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EJS42202.1 - 4.2e-08 33.5 0.0 8.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EJS42202.1 - 9.2e-08 32.7 0.0 1.6e-05 25.4 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EJS42202.1 - 4.6e-07 29.9 0.1 1.9e-06 27.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EJS42202.1 - 3.5e-05 24.1 1.0 0.0047 17.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EJS42202.1 - 0.00011 21.4 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EJS42202.1 - 0.00035 20.5 0.2 0.0012 18.8 0.0 2.0 3 0 0 3 3 2 1 NTPase RuvB_N PF05496.12 EJS42202.1 - 0.00035 20.4 0.0 0.001 18.8 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EJS42202.1 - 0.00045 20.0 0.2 0.0012 18.6 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 EJS42202.1 - 0.0012 19.3 0.0 0.012 16.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EJS42202.1 - 0.0014 18.4 0.0 0.0032 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EJS42202.1 - 0.0016 18.4 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EJS42202.1 - 0.0024 18.3 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 EJS42202.1 - 0.003 17.3 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EJS42202.1 - 0.0032 17.5 0.0 0.0073 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EJS42202.1 - 0.0033 17.0 0.0 0.029 13.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 EJS42202.1 - 0.0035 16.6 0.0 0.0062 15.8 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EJS42202.1 - 0.0035 17.5 0.1 0.0095 16.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain TniB PF05621.11 EJS42202.1 - 0.0039 16.6 0.0 0.33 10.3 0.0 2.6 3 0 0 3 3 3 1 Bacterial TniB protein AAA_3 PF07726.11 EJS42202.1 - 0.0055 16.6 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EJS42202.1 - 0.0068 16.1 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EJS42202.1 - 0.007 15.8 0.1 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EJS42202.1 - 0.01 15.8 0.1 0.082 12.8 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.6 EJS42202.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EJS42202.1 - 0.021 14.6 0.1 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EJS42202.1 - 0.023 14.6 0.6 0.28 11.1 0.0 2.5 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EJS42202.1 - 0.028 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EJS42202.1 - 0.11 12.9 0.1 0.31 11.4 0.1 1.8 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 EJS42202.1 - 0.12 12.9 0.1 0.41 11.2 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 EJS42202.1 - 0.2 11.2 2.1 0.5 9.9 0.1 2.3 2 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EJS42202.1 - 0.39 11.2 2.6 18 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EJS42202.1 - 0.57 9.5 3.5 2.5 7.4 0.3 2.7 2 1 0 3 3 3 0 DnaB-like helicase C terminal domain IBN_N PF03810.19 EJS42203.1 - 4.2e-20 71.4 0.6 1.4e-19 69.8 0.1 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 EJS42203.1 - 2.4e-06 26.6 0.5 2.4e-06 26.6 0.5 3.7 4 2 1 5 5 5 1 Cse1 Reticulon PF02453.17 EJS42203.1 - 0.053 13.5 0.3 0.053 13.5 0.3 2.2 2 0 0 2 2 2 0 Reticulon Vac14_Fab1_bd PF12755.7 EJS42203.1 - 1.2 9.8 4.4 1.1 9.9 0.1 3.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region RFC1 PF08519.12 EJS42203.1 - 3.1 8.0 5.3 10 6.2 0.1 3.3 4 0 0 4 4 4 0 Replication factor RFC1 C terminal domain Utp12 PF04003.12 EJS42204.1 - 2.1e-23 82.7 1.6 3.5e-23 81.9 1.6 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Mlh1_C PF16413.5 EJS42204.1 - 0.059 12.7 0.1 6.8 6.0 0.1 2.3 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus ANAPC4_WD40 PF12894.7 EJS42204.1 - 0.07 13.4 0.1 1.6 9.1 0.0 2.9 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJS42204.1 - 0.085 13.8 1.0 4.7 8.3 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat p450 PF00067.22 EJS42205.1 - 6.5e-54 183.4 0.0 8.2e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.12 EJS42206.1 - 2.3e-99 332.3 0.0 3.1e-99 331.9 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein BssC_TutF PF08201.11 EJS42206.1 - 0.02 14.9 0.1 0.06 13.4 0.1 1.8 1 0 0 1 1 1 0 BssC/TutF protein S1 PF00575.23 EJS42207.1 - 4.5e-18 65.4 0.1 6.6e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 EJS42207.1 - 8.9e-17 61.2 0.0 1.8e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 EJS42207.1 - 5.8e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 Ribosomal_L23 PF00276.20 EJS42208.1 - 5.4e-12 45.9 0.0 9.2e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 ABC2_membrane PF01061.24 EJS42209.1 - 1.6e-88 295.6 52.8 3.1e-46 157.4 24.6 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EJS42209.1 - 5.3e-38 130.6 0.0 9.5e-18 65.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EJS42209.1 - 4.7e-31 106.6 13.0 7.4e-31 105.9 0.2 3.5 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EJS42209.1 - 1.7e-19 70.2 0.4 6.4e-19 68.4 0.4 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EJS42209.1 - 1.5e-07 30.9 24.9 7.5e-05 22.0 10.5 2.7 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 EJS42209.1 - 3.2e-06 27.7 0.0 0.001 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EJS42209.1 - 3.9e-06 26.6 0.1 8.6e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EJS42209.1 - 2.8e-05 24.7 0.1 0.014 15.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EJS42209.1 - 0.00012 22.2 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EJS42209.1 - 0.00029 20.5 0.5 0.008 15.9 0.1 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJS42209.1 - 0.00047 20.1 0.1 0.0078 16.1 0.0 2.5 3 0 0 3 3 2 1 RsgA GTPase AAA_22 PF13401.6 EJS42209.1 - 0.00089 19.5 1.2 0.44 10.8 0.1 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 EJS42209.1 - 0.0012 18.5 0.4 1 8.9 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EJS42209.1 - 0.0013 18.2 0.1 0.039 13.4 0.1 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EJS42209.1 - 0.0023 17.8 0.1 0.25 11.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EJS42209.1 - 0.0031 17.4 0.3 3.4 7.6 0.2 2.7 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 EJS42209.1 - 0.0088 16.3 1.0 0.27 11.5 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EJS42209.1 - 0.038 14.5 3.4 0.041 14.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 EJS42209.1 - 0.052 13.3 0.6 4.2 7.0 0.5 2.7 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EJS42209.1 - 0.058 13.2 0.1 8.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA PF00004.29 EJS42209.1 - 0.095 13.1 0.0 17 5.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 EJS42209.1 - 0.097 12.0 0.0 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain OCD_Mu_crystall PF02423.15 EJS42209.1 - 0.14 11.0 0.0 0.49 9.3 0.0 1.8 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family TRAPPC9-Trs120 PF08626.11 EJS42210.1 - 0 1051.1 30.6 0 1050.9 30.6 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ALMT PF11744.8 EJS42210.1 - 0.012 14.5 2.1 0.019 13.8 2.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Formyl_trans_N PF00551.19 EJS42211.1 - 1.7e-59 200.6 0.0 2e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Glyco_trans_4_4 PF13579.6 EJS42211.1 - 0.041 14.3 0.0 0.055 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF3370 PF11850.8 EJS42211.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) PINIT PF14324.6 EJS42212.1 - 6.4e-33 114.1 0.0 6.4e-33 114.1 0.0 3.0 4 0 0 4 4 4 1 PINIT domain zf-MIZ PF02891.20 EJS42212.1 - 6.7e-22 77.0 7.4 1.5e-21 75.8 7.4 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 EJS42212.1 - 5.3e-10 38.8 0.0 8.9e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 EJS42212.1 - 9.3e-05 22.2 1.4 0.00023 20.9 1.4 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EJS42212.1 - 0.013 15.5 3.5 0.031 14.3 3.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EJS42212.1 - 0.11 12.3 4.7 0.24 11.3 4.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJS42212.1 - 1.5 9.2 4.3 2.9 8.3 4.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 EJS42212.1 - 2.2 8.5 4.1 4.3 7.6 4.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TT_ORF1 PF02956.14 EJS42212.1 - 7.6 5.1 12.2 12 4.4 12.2 1.2 1 0 0 1 1 1 0 TT viral orf 1 Nop25 PF09805.9 EJS42213.1 - 5.1e-38 130.6 19.4 5.1e-38 130.6 19.4 2.0 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) EXS PF03124.14 EJS42214.1 - 1.2e-55 189.2 30.5 1.3e-55 189.0 30.5 1.0 1 0 0 1 1 1 1 EXS family Peptidase_M28 PF04389.17 EJS42215.1 - 4.2e-27 95.1 0.0 8.4e-27 94.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 EJS42215.1 - 1.5e-06 28.1 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Pox_E6 PF04656.12 EJS42215.1 - 0.012 14.1 0.3 0.017 13.6 0.3 1.2 1 0 0 1 1 1 0 Pox virus E6 protein Ribosomal_L11_N PF03946.14 EJS42216.1 - 2.6e-21 75.2 0.3 4.6e-21 74.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EJS42216.1 - 6.2e-17 61.9 1.2 1.1e-16 61.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain IMS PF00817.20 EJS42217.1 - 1.2e-45 155.1 0.0 2.2e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 EJS42217.1 - 4.1e-09 35.9 0.5 1.3e-08 34.3 0.5 1.8 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 EJS42217.1 - 2.4e-07 31.5 0.1 7.3e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EJS42217.1 - 0.00049 20.3 0.1 0.0012 19.1 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif Sugar_tr PF00083.24 EJS42218.1 - 1.9e-172 574.2 36.7 2.2e-172 574.0 36.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS42218.1 - 6.2e-31 107.6 35.5 4.5e-28 98.2 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 EJS42218.1 - 5.5 6.5 7.3 9.8 5.7 3.1 3.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Svf1_C PF17187.4 EJS42219.1 - 1.6e-66 223.2 1.1 3.4e-66 222.1 1.1 1.6 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EJS42219.1 - 7.7e-63 211.4 0.0 1.4e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Astro_capsid_p PF12226.8 EJS42219.1 - 0.06 12.5 14.2 0.55 9.3 4.5 2.2 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Nop14 PF04147.12 EJS42219.1 - 0.48 8.6 24.1 0.17 10.0 3.9 2.1 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 EJS42219.1 - 0.79 9.0 20.5 0.48 9.7 6.4 2.1 2 0 0 2 2 2 0 BUD22 RXT2_N PF08595.11 EJS42219.1 - 1.8 8.6 13.0 2.9 7.9 3.6 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF5523 PF17661.1 EJS42219.1 - 2.1 8.0 17.2 2.8 7.6 1.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Prothymosin PF03247.14 EJS42219.1 - 2.8 8.4 40.9 0.39 11.2 18.8 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family Myc_N PF01056.18 EJS42219.1 - 3.4 7.5 13.9 6.7 6.5 1.9 2.2 2 0 0 2 2 2 0 Myc amino-terminal region PPP4R2 PF09184.11 EJS42219.1 - 3.9 7.0 23.9 0.17 11.5 5.9 2.2 2 0 0 2 2 2 0 PPP4R2 Sod_Fe_C PF02777.18 EJS42220.1 - 2.3e-14 53.4 0.3 7.9e-06 26.0 0.0 2.5 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Pal1 PF08316.11 EJS42221.1 - 1.5e-53 181.2 3.1 1.5e-53 181.2 3.1 2.9 4 1 0 4 4 4 1 Pal1 cell morphology protein Asp PF00026.23 EJS42222.1 - 2.5e-22 79.7 1.5 2e-21 76.7 1.5 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EJS42222.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal SBE2 PF17076.5 EJS42223.1 - 5e-255 848.7 35.0 6.5e-255 848.3 35.0 1.1 1 0 0 1 1 1 1 SBE2, cell-wall formation Colipase-like PF15083.6 EJS42223.1 - 0.034 14.3 0.8 0.12 12.5 0.1 2.3 3 0 0 3 3 3 0 Colipase-like Ribosomal_L27A PF00828.19 EJS42223.1 - 0.24 12.1 1.6 0.7 10.6 0.2 2.3 2 0 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PQ-loop PF04193.14 EJS42224.1 - 1.2e-35 121.1 10.5 1.7e-18 66.2 0.9 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EJS42224.1 - 0.011 16.6 1.1 0.1 13.4 0.0 2.8 2 1 1 3 3 3 0 ER lumen protein retaining receptor MtN3_slv PF03083.16 EJS42224.1 - 0.04 13.9 5.1 0.95 9.5 0.2 3.5 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange Pyr_redox_2 PF07992.14 EJS42225.1 - 7.9e-51 173.0 0.1 9.1e-51 172.8 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJS42225.1 - 6.9e-19 68.2 0.3 7.9e-16 58.4 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJS42225.1 - 2.8e-15 56.4 0.1 6.8e-14 51.8 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJS42225.1 - 3.9e-06 26.2 0.4 0.53 9.3 0.1 4.0 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EJS42225.1 - 0.00024 21.5 0.0 0.067 13.6 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EJS42225.1 - 0.00027 21.1 0.0 0.025 14.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJS42225.1 - 0.00082 18.6 0.7 0.41 9.7 0.2 2.6 1 1 1 2 2 2 2 FAD binding domain Thi4 PF01946.17 EJS42225.1 - 0.004 16.4 0.0 0.015 14.6 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EJS42225.1 - 0.011 15.1 0.1 2.5 7.3 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EJS42225.1 - 0.023 14.3 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 EJS42225.1 - 0.033 13.3 0.1 3.2 6.8 0.0 3.3 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EJS42225.1 - 0.039 12.7 0.2 2 7.0 0.1 2.6 2 1 1 3 3 3 0 HI0933-like protein Shikimate_DH PF01488.20 EJS42225.1 - 0.073 13.1 0.3 12 5.9 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 EJS42225.1 - 0.1 11.9 0.1 0.54 9.5 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glycos_transf_3 PF00591.21 EJS42226.1 - 8.2e-88 294.3 0.0 1e-87 293.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EJS42226.1 - 3.2e-08 33.3 0.0 6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Spc110_C PF18520.1 EJS42227.1 - 1.5e-22 78.9 0.4 1.5e-22 78.9 0.4 4.3 4 0 0 4 4 4 1 Spindle pole body component 110 C-terminal domain Spc7 PF08317.11 EJS42227.1 - 2.6e-05 23.3 150.8 7.9e-05 21.7 23.3 6.2 1 1 5 6 6 6 3 Spc7 kinetochore protein Filament PF00038.21 EJS42227.1 - 0.0024 17.5 60.1 0.0024 17.5 60.1 6.3 1 1 4 5 5 5 2 Intermediate filament protein TPR_MLP1_2 PF07926.12 EJS42227.1 - 0.011 15.8 20.8 0.011 15.8 20.8 7.8 1 1 6 8 8 8 0 TPR/MLP1/MLP2-like protein Surfac_D-trimer PF09006.11 EJS42227.1 - 0.096 12.6 0.1 2.4 8.1 0.0 2.9 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation ATG16 PF08614.11 EJS42227.1 - 0.32 11.2 138.6 0.62 10.3 12.8 7.0 2 1 4 6 6 6 0 Autophagy protein 16 (ATG16) DUF4686 PF15742.5 EJS42227.1 - 0.58 9.2 154.2 4.6 6.3 42.1 5.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4686) DUF3584 PF12128.8 EJS42227.1 - 1.2 6.5 128.9 0.11 10.0 41.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) MtrG PF04210.13 EJS42227.1 - 3.6 7.5 4.9 17 5.4 0.0 4.1 2 1 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4407 PF14362.6 EJS42227.1 - 6.8 6.0 97.3 3.5 6.9 15.0 5.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) VHS PF00790.19 EJS42228.1 - 1.3e-48 164.4 0.0 4e-48 162.9 0.0 1.8 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EJS42228.1 - 1.7e-18 66.7 2.0 1.7e-18 66.7 2.0 3.7 3 1 0 3 3 3 1 GAT domain Alpha_adaptinC2 PF02883.20 EJS42228.1 - 2.4e-16 60.0 0.2 4.9e-16 59.0 0.2 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 EJS42228.1 - 7.4e-08 31.9 0.2 7.4e-08 31.9 0.2 3.2 3 0 0 3 3 3 1 GGA N-GAT domain BCIP PF13862.6 EJS42229.1 - 8.4e-49 166.2 0.9 8.4e-49 166.2 0.9 1.9 2 0 0 2 2 2 1 p21-C-terminal region-binding protein YL1 PF05764.13 EJS42230.1 - 0.0033 17.6 4.4 0.0049 17.0 4.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DSS1_SEM1 PF05160.13 EJS42231.1 - 1.8e-20 72.7 14.4 2.5e-20 72.3 14.4 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family WD40 PF00400.32 EJS42232.1 - 2.8e-29 100.7 10.5 2.3e-07 31.4 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS42232.1 - 2.2e-08 34.3 0.1 0.039 14.3 0.0 3.9 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain FRG1 PF06229.12 EJS42232.1 - 0.063 13.0 1.8 0.2 11.3 1.8 1.8 1 0 0 1 1 1 0 FRG1-like domain NUC153 PF08159.12 EJS42233.1 - 7.3e-15 54.5 9.6 1.8e-14 53.2 1.8 2.9 3 0 0 3 3 3 2 NUC153 domain Aldo_ket_red PF00248.21 EJS42234.1 - 5.3e-47 160.4 0.0 4.1e-45 154.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SpoU_sub_bind PF08032.12 EJS42234.1 - 0.01 16.1 0.1 0.2 11.9 0.0 2.7 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding GPP34 PF05719.11 EJS42235.1 - 4.9e-66 222.6 0.0 6.3e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) EF-hand_1 PF00036.32 EJS42236.1 - 5.9e-26 88.1 5.2 9.3e-08 31.1 0.3 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EJS42236.1 - 6.2e-23 78.7 4.6 2.1e-06 27.2 0.2 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 EJS42236.1 - 2.2e-22 79.3 6.1 6.2e-16 58.6 0.3 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EJS42236.1 - 2e-17 61.8 1.8 2.8e-05 23.4 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EJS42236.1 - 2.5e-16 59.3 8.9 2.1e-07 30.7 1.6 3.7 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 EJS42236.1 - 3.6e-05 23.7 3.3 0.63 10.0 0.0 3.4 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EJS42236.1 - 4.2e-05 23.8 0.1 0.0063 16.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EJS42236.1 - 6.9e-05 23.1 0.7 0.0062 16.8 0.4 2.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region AAA_34 PF13872.6 EJS42236.1 - 0.015 14.2 0.1 1.4 7.7 0.0 2.1 1 1 1 2 2 2 0 P-loop containing NTP hydrolase pore-1 PHB_acc_N PF07879.11 EJS42236.1 - 0.041 14.0 0.1 3.1 8.0 0.1 2.6 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain S10_plectin PF03501.15 EJS42236.1 - 0.056 13.5 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_13 PF17958.1 EJS42236.1 - 0.061 13.1 0.0 1.9 8.4 0.0 3.0 4 1 0 4 4 4 0 EF-hand domain DUF1707 PF08044.11 EJS42236.1 - 0.15 12.2 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) YTH PF04146.15 EJS42237.1 - 9.5e-35 120.0 0.5 2e-34 119.0 0.5 1.5 1 0 0 1 1 1 1 YT521-B-like domain Importin_rep_6 PF18829.1 EJS42238.1 - 0.11 12.7 0.1 0.26 11.4 0.1 1.4 1 1 1 2 2 2 0 Importin repeat 6 BCS1_N PF08740.11 EJS42239.1 - 1e-46 159.3 0.0 1.4e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EJS42239.1 - 2.9e-23 82.7 0.0 5.1e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EJS42239.1 - 0.00089 18.8 0.0 0.0095 15.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RuvB_N PF05496.12 EJS42239.1 - 0.0011 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EJS42239.1 - 0.0025 17.0 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EJS42239.1 - 0.0029 17.8 0.0 0.0069 16.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EJS42239.1 - 0.0031 17.9 0.0 0.013 15.9 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EJS42239.1 - 0.004 17.2 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EJS42239.1 - 0.0054 17.3 0.0 0.016 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EJS42239.1 - 0.009 15.9 0.0 0.33 10.9 0.0 2.7 2 1 1 3 3 3 1 NACHT domain ABC_tran PF00005.27 EJS42239.1 - 0.012 16.1 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EJS42239.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EJS42239.1 - 0.02 14.6 0.0 0.067 13.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase PF06745.13 EJS42239.1 - 0.035 13.5 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.22 EJS42239.1 - 0.035 14.5 0.0 0.09 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_21 PF13304.6 EJS42239.1 - 0.048 13.5 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EJS42239.1 - 0.049 13.6 0.0 0.65 9.9 0.0 2.2 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 EJS42239.1 - 0.062 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RcnB PF11776.8 EJS42239.1 - 0.068 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator ATPase_2 PF01637.18 EJS42239.1 - 0.084 12.8 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EJS42239.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gram_pos_anchor PF00746.21 EJS42239.1 - 0.28 11.2 0.8 0.58 10.1 0.8 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif F1F0-ATPsyn_F PF10791.9 EJS42240.1 - 1.7e-41 140.6 0.2 1.9e-41 140.4 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 EJS42240.1 - 0.013 15.8 0.0 0.017 15.5 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f RhoGAP PF00620.27 EJS42241.1 - 2e-45 154.4 0.7 4e-45 153.3 0.7 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EJS42241.1 - 1.4e-15 57.2 28.7 6.9e-10 39.0 7.6 2.6 2 0 0 2 2 2 2 LIM domain zinc_ribbon_2 PF13240.6 EJS42241.1 - 0.069 12.9 0.2 0.069 12.9 0.2 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Complex1_LYR PF05347.15 EJS42242.1 - 6.8e-13 48.4 0.1 7.8e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) TPP_enzyme_N PF02776.18 EJS42243.1 - 1e-26 93.6 0.0 1.7e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EJS42243.1 - 1.4e-22 79.9 0.0 2.4e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EJS42243.1 - 4.4e-16 59.0 0.0 1.1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ribosomal_60s PF00428.19 EJS42244.1 - 8.6e-23 80.7 14.3 1.1e-22 80.5 14.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein FTA4 PF13093.6 EJS42245.1 - 0.00083 19.3 3.3 0.0011 18.9 3.3 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Snapin_Pallidin PF14712.6 EJS42245.1 - 0.025 15.0 1.8 4.2 7.9 0.1 2.7 2 0 0 2 2 2 0 Snapin/Pallidin WXG100 PF06013.12 EJS42245.1 - 0.089 13.0 0.0 2.3 8.5 0.1 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Gpr1_Fun34_YaaH PF01184.19 EJS42246.1 - 3.7e-72 242.3 14.4 4.5e-72 242.0 14.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ApbA_C PF08546.11 EJS42247.1 - 9.9e-05 22.5 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal GIT_CC PF16559.5 EJS42247.1 - 0.00034 20.4 1.1 0.0013 18.5 1.1 2.0 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor Tropomyosin_1 PF12718.7 EJS42247.1 - 0.24 11.5 11.8 0.051 13.7 2.4 2.4 2 0 0 2 2 2 0 Tropomyosin like NAC PF01849.18 EJS42248.1 - 2.8e-14 52.8 0.0 6.6e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 NAC domain Ribosomal_L18 PF17135.4 EJS42248.1 - 0.031 13.6 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e CENP-N PF05238.13 EJS42249.1 - 1.3e-102 344.2 0.0 1.8e-102 343.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like CLTH PF10607.9 EJS42250.1 - 1.8e-10 40.9 0.4 1.8e-10 40.9 0.4 2.8 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EJS42250.1 - 6.4e-05 22.9 0.4 0.0002 21.3 0.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger DUF3631 PF12307.8 EJS42250.1 - 0.024 14.9 0.4 3.8 7.7 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3631) zf-RING_5 PF14634.6 EJS42250.1 - 0.028 14.4 0.5 0.097 12.7 0.5 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EJS42250.1 - 0.047 14.0 0.8 0.14 12.5 0.8 1.9 1 0 0 1 1 1 0 Ring finger domain DUF1729 PF08354.10 EJS42250.1 - 0.15 10.9 1.2 0.3 9.9 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) zf-RING_7 PF02591.15 EJS42250.1 - 0.2 11.9 0.1 0.58 10.4 0.1 1.8 1 0 0 1 1 1 0 C4-type zinc ribbon domain Ku_PK_bind PF08785.11 EJS42250.1 - 0.23 11.6 6.7 1.1 9.5 4.1 2.4 2 0 0 2 2 2 0 Ku C terminal domain like MRP-L51 PF10244.9 EJS42250.1 - 0.35 11.1 4.4 1.2 9.4 4.4 2.0 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit Tmemb_9 PF05434.11 EJS42250.1 - 0.43 10.5 10.8 0.6 10.0 6.3 2.4 2 0 0 2 2 2 0 TMEM9 SET PF00856.28 EJS42251.1 - 2.4e-20 73.6 0.0 5.4e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 SET domain AAA_2 PF07724.14 EJS42252.1 - 3e-51 174.0 0.1 4.6e-49 166.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EJS42252.1 - 3.4e-36 123.3 6.4 9.2e-36 121.9 0.5 2.8 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EJS42252.1 - 9.2e-26 89.7 0.6 3.5e-25 87.9 0.6 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EJS42252.1 - 1.7e-21 77.0 0.1 6.6e-11 42.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EJS42252.1 - 3.3e-15 56.3 0.2 1.2e-10 41.6 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EJS42252.1 - 1.9e-10 41.4 5.4 0.00049 20.5 0.1 4.4 3 2 0 4 4 3 2 AAA ATPase domain ATPase_2 PF01637.18 EJS42252.1 - 3.6e-08 33.6 0.5 0.088 12.7 0.0 4.0 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea TniB PF05621.11 EJS42252.1 - 2.9e-07 30.1 0.1 0.00022 20.7 0.0 4.0 3 1 0 3 3 3 1 Bacterial TniB protein AAA_22 PF13401.6 EJS42252.1 - 3.8e-07 30.5 0.1 0.037 14.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EJS42252.1 - 6.2e-07 29.3 0.1 2.7e-05 24.0 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 EJS42252.1 - 1.2e-06 28.5 0.0 0.021 14.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EJS42252.1 - 3.7e-06 26.8 0.1 0.041 13.6 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_7 PF12775.7 EJS42252.1 - 4.2e-06 26.4 0.1 0.019 14.5 0.0 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 EJS42252.1 - 0.00013 21.9 0.0 0.13 12.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 EJS42252.1 - 0.00022 21.2 0.0 1.1 9.3 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EJS42252.1 - 0.00025 21.6 0.2 0.12 12.8 0.0 3.0 3 0 0 3 3 2 1 ABC transporter RsgA_GTPase PF03193.16 EJS42252.1 - 0.00055 19.9 0.0 0.4 10.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EJS42252.1 - 0.0006 20.4 5.3 0.46 11.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 EJS42252.1 - 0.0007 18.9 0.0 0.017 14.4 0.0 3.0 2 1 1 3 3 3 1 Zeta toxin AAA_30 PF13604.6 EJS42252.1 - 0.0012 18.7 0.8 1.9 8.2 0.0 3.2 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 EJS42252.1 - 0.0012 19.2 0.0 1.8 9.0 0.0 3.1 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 EJS42252.1 - 0.0014 18.4 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EJS42252.1 - 0.0022 18.2 0.0 0.46 10.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_6 PF12774.7 EJS42252.1 - 0.0023 16.9 0.0 0.15 11.0 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_21 PF13304.6 EJS42252.1 - 0.0026 17.6 0.2 4.3 7.0 0.0 3.7 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 EJS42252.1 - 0.0027 17.4 0.1 0.43 10.3 0.0 2.9 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EJS42252.1 - 0.0063 16.7 0.0 4.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EJS42252.1 - 0.0068 15.6 0.9 4.1 6.5 0.2 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 EJS42252.1 - 0.012 15.2 0.1 0.63 9.6 0.0 3.0 4 0 0 4 4 3 0 AAA domain SRP54 PF00448.22 EJS42252.1 - 0.013 15.1 0.0 1.9 8.1 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Torsin PF06309.11 EJS42252.1 - 0.014 15.5 0.0 0.091 12.9 0.0 2.2 2 0 0 2 2 2 0 Torsin T2SSE PF00437.20 EJS42252.1 - 0.016 14.3 0.4 0.11 11.5 0.1 2.5 2 1 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 EJS42252.1 - 0.02 14.2 0.0 1.5 8.1 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 EJS42252.1 - 0.028 14.5 0.4 1.7 8.7 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_24 PF13479.6 EJS42252.1 - 0.034 13.8 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EJS42252.1 - 0.064 13.4 0.0 6.9 6.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EJS42252.1 - 0.065 12.7 0.0 3.6 7.0 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 EJS42252.1 - 0.096 12.5 0.0 1.8 8.4 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EJS42252.1 - 0.12 12.4 0.0 9.8 6.3 0.1 3.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase CENP-F_leu_zip PF10473.9 EJS42252.1 - 0.48 10.4 12.3 0.33 11.0 4.0 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cob_adeno_trans PF01923.18 EJS42252.1 - 0.64 10.2 2.8 3.3 7.8 1.3 2.4 2 0 0 2 2 2 0 Cobalamin adenosyltransferase AAA_23 PF13476.6 EJS42252.1 - 2 8.9 21.1 9.8 6.6 0.6 3.7 2 2 0 2 2 2 0 AAA domain Prefoldin PF02996.17 EJS42252.1 - 2.4 8.1 7.2 23 4.9 0.2 3.9 4 1 0 4 4 3 0 Prefoldin subunit Apc13p PF05839.11 EJS42253.1 - 1e-27 96.1 0.2 1.7e-27 95.4 0.2 1.3 1 0 0 1 1 1 1 Apc13p protein Pex2_Pex12 PF04757.14 EJS42254.1 - 9.5e-32 110.4 5.3 2.1e-31 109.3 5.3 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 EJS42254.1 - 1.7e-08 34.7 17.5 3e-08 33.8 17.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EJS42254.1 - 1.7e-07 31.0 17.0 2.8e-07 30.3 17.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJS42254.1 - 3.8e-06 26.7 16.1 7.4e-06 25.7 16.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJS42254.1 - 4.7e-06 26.4 16.1 8.4e-06 25.6 16.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EJS42254.1 - 1.8e-05 24.6 10.3 1.8e-05 24.6 10.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EJS42254.1 - 2.6e-05 23.9 17.8 5e-05 23.0 17.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EJS42254.1 - 0.00061 20.0 12.1 0.0016 18.7 12.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EJS42254.1 - 0.0016 18.3 11.9 0.0033 17.3 11.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EJS42254.1 - 0.011 15.9 16.8 0.024 14.8 16.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EJS42254.1 - 1.4 8.8 8.8 2.7 7.9 8.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.21 EJS42254.1 - 6.1 7.1 14.8 5.2 7.4 12.6 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 EJS42255.1 - 7.1e-08 32.2 9.6 7.1e-08 32.2 9.6 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 EJS42255.1 - 0.24 12.3 0.3 0.24 12.3 0.3 6.9 7 2 1 8 8 8 0 C2H2-type zinc finger Ribosomal_L18_c PF14204.6 EJS42255.1 - 1.7 9.6 5.6 0.29 12.1 0.8 2.3 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region tRNA-synt_1b PF00579.25 EJS42256.1 - 1.3e-83 280.8 0.0 1.7e-83 280.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HAGH_C PF16123.5 EJS42257.1 - 2.2e-19 69.7 0.1 3.8e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EJS42257.1 - 2.2e-10 40.9 0.1 8.2e-09 35.7 0.1 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EJS42257.1 - 0.0005 19.6 0.4 0.002 17.6 0.4 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EJS42257.1 - 0.065 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Gp-FAR-1 PF05823.12 EJS42257.1 - 0.09 13.1 0.2 0.17 12.3 0.2 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Pmp3 PF01679.17 EJS42258.1 - 2.3e-17 62.9 8.4 2.4e-17 62.8 8.4 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator STD1 PF17235.2 EJS42259.1 - 4.5e-75 251.8 0.7 4.5e-75 251.8 0.7 1.6 2 0 0 2 2 2 1 STD1/MTH1 DUF915 PF06028.11 EJS42259.1 - 0.015 14.6 0.5 0.027 13.8 0.5 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DNA_pol_B_thumb PF14791.6 EJS42259.1 - 0.12 12.5 0.2 0.46 10.7 0.2 2.0 1 1 0 1 1 1 0 DNA polymerase beta thumb Tir_receptor_C PF07489.11 EJS42259.1 - 0.38 10.7 5.0 0.67 9.9 5.0 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus RNase_H2-Ydr279 PF09468.10 EJS42260.1 - 9.9e-18 64.8 0.4 4.9e-17 62.6 0.0 2.3 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EJS42260.1 - 8.8e-13 48.3 0.2 1.6e-12 47.5 0.2 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain HGTP_anticodon2 PF12745.7 EJS42261.1 - 1.4e-90 303.3 4.3 1.4e-90 303.3 4.3 2.6 4 0 0 4 4 4 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 EJS42261.1 - 9.2e-73 244.8 12.1 5.4e-43 147.3 0.2 3.9 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42261.1 - 3e-39 134.9 0.2 3.3e-24 85.6 0.0 3.7 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EJS42261.1 - 5.1e-16 59.0 2.1 5.1e-16 59.0 2.1 2.6 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 EJS42261.1 - 8.6e-15 54.8 0.0 1.9e-14 53.6 0.0 1.6 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 EJS42261.1 - 0.0073 15.7 0.0 0.92 8.8 0.0 2.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EJS42261.1 - 0.0078 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EJS42261.1 - 0.029 13.7 0.3 0.37 10.1 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EJS42261.1 - 0.22 11.1 7.4 1.8 8.1 0.1 3.7 4 0 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 TPR_MLP1_2 PF07926.12 EJS42262.1 - 0.00021 21.4 24.9 0.00021 21.4 24.9 7.1 3 2 3 7 7 7 3 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 EJS42262.1 - 0.0018 18.7 0.3 0.0018 18.7 0.3 4.4 4 1 0 4 4 4 2 Bacterial type III secretion protein (HrpB7) Phg_2220_C PF09524.10 EJS42262.1 - 0.96 9.6 7.0 0.88 9.7 2.3 3.4 2 1 1 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) Inositol_P PF00459.25 EJS42263.1 - 2e-70 237.4 0.0 2.3e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MAGE PF01454.19 EJS42264.1 - 2.3e-45 155.0 0.1 3e-45 154.6 0.1 1.2 1 0 0 1 1 1 1 MAGE family SMC_ScpB PF04079.16 EJS42264.1 - 0.065 12.9 0.3 0.99 9.0 0.1 2.4 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB RNA_pol_Rpb5_C PF01191.19 EJS42264.1 - 0.11 12.4 0.3 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain SRX PF09201.10 EJS42265.1 - 1.1e-66 223.2 6.7 2.8e-66 221.9 6.7 1.7 1 0 0 1 1 1 1 SRX, signal recognition particle receptor alpha subunit SRP54 PF00448.22 EJS42265.1 - 1e-46 159.1 0.1 2.9e-44 151.1 0.1 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EJS42265.1 - 1.6e-06 28.3 0.2 5.7e-06 26.5 0.2 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EJS42265.1 - 0.0011 18.0 0.0 0.0024 16.9 0.0 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EJS42265.1 - 0.0015 18.5 0.0 0.0042 17.1 0.0 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EJS42265.1 - 0.0018 18.2 0.1 0.017 15.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EJS42265.1 - 0.0037 16.5 0.0 0.31 10.2 0.0 2.4 2 0 0 2 2 2 1 Anion-transporting ATPase cobW PF02492.19 EJS42265.1 - 0.004 16.7 0.0 0.0088 15.6 0.0 1.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Fer4_NifH PF00142.18 EJS42265.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.6 EJS42265.1 - 0.033 13.9 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EJS42265.1 - 0.083 13.2 0.0 0.34 11.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EJS42265.1 - 1.1 9.3 8.7 1 9.4 0.2 3.7 4 0 0 4 4 4 0 Helicase HerA, central domain Pyridoxal_deC PF00282.19 EJS42266.1 - 6.3e-23 81.1 0.0 9.1e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EJS42266.1 - 1.4e-07 30.8 0.0 1.1e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EJS42266.1 - 2.1e-07 30.6 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EJS42266.1 - 0.17 10.4 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SepSecS PF05889.13 EJS42266.1 - 0.18 10.5 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS HDA2-3 PF11496.8 EJS42267.1 - 1.1e-67 228.3 5.4 1.1e-67 228.3 5.4 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Mod_r PF07200.13 EJS42267.1 - 0.0041 17.2 12.4 0.0041 17.2 12.4 2.7 2 1 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein rve_2 PF13333.6 EJS42267.1 - 0.019 15.1 0.5 0.1 12.8 0.5 2.3 1 0 0 1 1 1 0 Integrase core domain DUF2205 PF10224.9 EJS42267.1 - 0.026 14.5 0.4 0.026 14.5 0.4 3.3 2 1 1 3 3 3 0 Short coiled-coil protein CorA PF01544.18 EJS42267.1 - 0.81 9.0 4.4 2 7.7 4.4 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF812 PF05667.11 EJS42267.1 - 1.9 7.3 22.7 0.58 9.0 15.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TSC22 PF01166.18 EJS42267.1 - 3.9 7.8 10.7 2.7 8.4 2.1 3.4 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.21 EJS42267.1 - 5.8 7.1 17.1 0.85 9.8 1.3 3.9 1 1 2 3 3 3 0 bZIP transcription factor DivIC PF04977.15 EJS42267.1 - 7.1 6.5 15.6 1.1 9.1 0.1 3.5 2 1 2 4 4 4 0 Septum formation initiator Mhr1 PF12829.7 EJS42268.1 - 1.2e-25 89.4 2.1 2.2e-25 88.6 2.1 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination FA_hydroxylase PF04116.13 EJS42269.1 - 3e-23 82.6 19.5 8.8e-23 81.1 11.6 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily OSCP PF00213.18 EJS42270.1 - 6.3e-43 146.9 1.2 7.4e-43 146.6 1.2 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit dCache_1 PF02743.18 EJS42270.1 - 0.018 14.9 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Cache domain SKIP_SNW PF02731.15 EJS42270.1 - 0.037 13.7 0.1 0.11 12.2 0.0 1.7 1 1 1 2 2 2 0 SKIP/SNW domain AATF-Che1 PF13339.6 EJS42271.1 - 5.4e-25 88.7 4.9 5.4e-25 88.7 4.9 3.5 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 EJS42271.1 - 6.3e-24 84.3 0.3 6.3e-24 84.3 0.3 3.9 3 1 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal Cas_Cas6 PF01881.16 EJS42271.1 - 4.8 7.7 6.6 2.2 8.9 0.4 2.7 2 1 0 2 2 2 0 CRISPR associated protein Cas6 AA_kinase PF00696.28 EJS42272.1 - 3e-35 121.9 0.8 9.2e-35 120.4 0.3 1.9 2 1 1 3 3 3 1 Amino acid kinase family PUA PF01472.20 EJS42272.1 - 8.1e-24 83.4 0.0 1.6e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 PUA domain CPSF_A PF03178.15 EJS42273.1 - 5.4e-91 305.3 0.0 1.5e-90 303.8 0.0 1.8 1 0 0 1 1 1 1 CPSF A subunit region PIG-F PF06699.11 EJS42274.1 - 9.6e-25 87.8 23.2 1.7e-23 83.7 23.2 2.1 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Uroplakin_II PF07353.12 EJS42274.1 - 0.033 13.7 0.1 0.063 12.8 0.0 1.5 1 1 0 1 1 1 0 Uroplakin II TauE PF01925.19 EJS42274.1 - 0.19 11.3 9.0 0.96 9.0 8.7 2.2 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF2070 PF09843.9 EJS42274.1 - 0.89 7.8 8.8 0.97 7.6 8.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Zn_clus PF00172.18 EJS42275.1 - 2e-08 34.2 6.5 4.1e-08 33.2 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EST1 PF10374.9 EJS42275.1 - 7.5 7.2 7.9 0.6 10.7 0.6 2.9 3 0 0 3 3 3 0 Telomerase activating protein Est1 Pro_isomerase PF00160.21 EJS42276.1 - 1.3e-45 155.5 0.2 1.8e-45 155.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.7 EJS42277.1 - 0.012 15.4 0.3 0.049 13.5 0.0 2.2 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EJS42277.1 - 0.11 12.4 1.7 21 5.1 0.0 3.9 4 0 0 4 4 4 0 F-box domain LRR_5 PF13306.6 EJS42277.1 - 0.22 11.5 10.0 0.2 11.6 1.3 3.5 1 1 2 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Med21 PF11221.8 EJS42278.1 - 7.6e-46 156.0 5.2 9.1e-46 155.7 5.2 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 EJS42278.1 - 0.00072 19.6 3.4 0.0051 16.9 3.2 2.2 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF2200 PF09966.9 EJS42278.1 - 0.037 14.2 1.0 0.84 9.8 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) Spore_III_AB PF09548.10 EJS42278.1 - 0.12 12.5 1.2 0.17 12.0 1.2 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) STAT_alpha PF01017.20 EJS42278.1 - 0.34 10.8 4.7 1.5 8.7 4.7 1.9 1 1 0 1 1 1 0 STAT protein, all-alpha domain betaPIX_CC PF16523.5 EJS42279.1 - 6.4 6.7 13.0 0.46 10.4 4.4 2.8 2 0 0 2 2 2 0 betaPIX coiled coil FYVE PF01363.21 EJS42280.1 - 4e-20 71.7 14.3 4e-20 71.7 14.3 3.4 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.6 EJS42280.1 - 3.6e-07 30.4 5.5 3.6e-07 30.4 5.5 4.8 5 1 1 6 6 6 1 Ring finger domain zf-RING_11 PF17123.5 EJS42280.1 - 7.6e-06 25.6 4.5 7.6e-06 25.6 4.5 3.5 4 0 0 4 4 4 1 RING-like zinc finger RNF220 PF15926.5 EJS42280.1 - 4.6e-05 23.2 4.1 4.6e-05 23.2 4.1 2.1 2 1 1 3 3 3 1 E3 ubiquitin-protein ligase RNF220 zf-RING_UBOX PF13445.6 EJS42280.1 - 0.00074 19.5 4.4 0.00074 19.5 4.4 4.9 5 1 1 6 6 6 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EJS42280.1 - 0.0036 17.1 6.0 0.0036 17.1 6.0 5.2 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJS42280.1 - 0.011 15.6 6.1 0.011 15.6 6.1 4.9 4 2 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJS42280.1 - 0.031 14.2 32.0 0.15 12.0 6.1 5.3 5 0 0 5 5 5 0 zinc-RING finger domain Dmrt1 PF12374.8 EJS42280.1 - 0.069 13.6 0.2 0.17 12.4 0.2 1.6 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 zf-C3HC4_4 PF15227.6 EJS42280.1 - 1.2 9.3 25.6 0.61 10.3 2.9 5.0 4 2 0 4 4 4 0 zinc finger of C3HC4-type, RING BHD_3 PF10405.9 EJS42281.1 - 2.1e-14 53.7 0.1 4.5e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EJS42281.1 - 4.8e-10 39.1 0.0 2.1e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.15 EJS42281.1 - 0.00075 19.2 0.7 0.0033 17.1 0.7 2.2 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 EJS42281.1 - 0.0072 17.3 1.6 0.011 16.7 0.1 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Corona_5a PF06336.11 EJS42281.1 - 0.074 13.0 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 Coronavirus 5a protein Ins_P5_2-kin PF06090.12 EJS42282.1 - 7.4e-17 61.8 1.3 6.1e-15 55.5 1.3 2.1 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Methyltransf_23 PF13489.6 EJS42283.1 - 1.6e-22 80.1 0.1 2.7e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJS42283.1 - 3.8e-15 56.4 0.1 2.9e-14 53.6 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS42283.1 - 4e-12 46.7 0.0 1.3e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJS42283.1 - 1.3e-10 41.0 0.5 1.1e-08 34.7 0.1 2.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EJS42283.1 - 2.9e-09 37.4 0.0 1.6e-08 35.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJS42283.1 - 1.3e-08 34.8 0.4 4.9e-08 32.9 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain YrhC PF14143.6 EJS42283.1 - 0.081 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 YrhC-like protein COX16 PF14138.6 EJS42283.1 - 2 9.0 9.3 1 9.9 4.5 3.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein COX16 HIM1 PF08732.10 EJS42284.1 - 9.1e-69 230.3 0.0 1.6e-68 229.5 0.0 1.4 1 0 0 1 1 1 1 HIM1 Scs3p PF10261.9 EJS42285.1 - 9.2e-15 54.8 23.1 1.9e-11 44.0 23.0 2.8 1 1 1 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 EJS42285.1 - 8.1e-06 25.6 6.6 7.4e-05 22.5 4.9 2.4 2 1 0 2 2 2 1 PAP2 superfamily Ubiq-assoc PF09145.10 EJS42286.1 - 1.7e-21 75.9 2.4 4.2e-21 74.7 2.4 1.7 1 0 0 1 1 1 1 Ubiquitin-associated TPR_2 PF07719.17 EJS42286.1 - 8.4e-06 25.5 0.0 0.69 10.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJS42286.1 - 7.8e-05 22.3 0.0 2 8.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJS42286.1 - 0.0031 17.8 0.1 15 6.0 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat Apis_Csd PF11671.8 EJS42286.1 - 0.014 15.5 0.1 0.038 14.0 0.1 1.7 1 0 0 1 1 1 0 Complementary sex determiner protein DnaJ PF00226.31 EJS42286.1 - 0.038 14.1 0.4 0.24 11.6 0.0 2.5 2 0 0 2 2 2 0 DnaJ domain TPR_6 PF13174.6 EJS42286.1 - 0.061 14.0 0.0 0.72 10.6 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJS42286.1 - 0.16 12.3 0.1 41 4.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DASH_Dad4 PF08650.10 EJS42287.1 - 1.6e-33 114.4 4.4 1.8e-33 114.3 4.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 NPV_P10 PF05531.12 EJS42287.1 - 0.032 14.7 0.4 0.035 14.6 0.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Img2 PF05046.14 EJS42287.1 - 0.096 13.0 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Asparaginase PF00710.20 EJS42288.1 - 3.5e-55 186.5 0.0 6.8e-55 185.6 0.0 1.5 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EJS42288.1 - 3.4e-18 65.9 0.0 7e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ribosomal_L19 PF01245.20 EJS42288.1 - 0.012 15.5 0.0 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 Ribosomal protein L19 PBP PF01161.20 EJS42289.1 - 5.4e-07 30.0 0.0 1.2e-06 28.8 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein Mob1_phocein PF03637.17 EJS42289.1 - 0.032 14.3 0.3 0.052 13.6 0.3 1.3 1 0 0 1 1 1 0 Mob1/phocein family ATP-synt_E PF05680.12 EJS42290.1 - 1.2e-17 64.0 0.0 1.3e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain FYVE PF01363.21 EJS42291.1 - 1.1e-17 64.0 23.7 5.2e-15 55.3 2.4 3.2 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EJS42291.1 - 9.5e-13 47.7 2.1 5.5e-12 45.2 0.1 3.1 3 0 0 3 3 3 1 Rabenosyn Rab binding domain zf-C2H2_6 PF13912.6 EJS42291.1 - 0.019 14.9 0.0 0.019 14.9 0.0 3.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf-Di19 PF05605.12 EJS42291.1 - 0.04 14.2 0.1 0.04 14.2 0.1 2.9 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 EJS42291.1 - 0.051 13.4 0.1 0.23 11.4 0.1 2.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 EJS42291.1 - 0.14 13.0 0.1 0.14 13.0 0.1 5.9 7 1 1 8 8 8 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EJS42291.1 - 0.6 10.7 0.1 0.6 10.7 0.1 5.3 5 1 1 6 6 6 0 Zinc finger, C2H2 type CorA PF01544.18 EJS42291.1 - 1.1 8.5 4.1 1.4 8.2 1.3 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein HypA PF01155.19 EJS42291.1 - 1.7 8.7 12.4 4.1 7.5 4.2 3.3 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Siva PF05458.12 EJS42291.1 - 1.8 8.2 9.7 2 8.1 0.5 2.5 2 0 0 2 2 2 0 Cd27 binding protein (Siva) VASt PF16016.5 EJS42292.1 - 2.3e-73 245.7 4.6 1.1e-35 123.4 0.1 2.9 2 0 0 2 2 2 2 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EJS42292.1 - 1.3e-25 89.5 0.1 3.5e-25 88.1 0.1 1.8 1 0 0 1 1 1 1 GRAM domain Skp1 PF01466.19 EJS42293.1 - 9.1e-25 86.5 0.1 1.5e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EJS42293.1 - 1.3e-15 57.3 0.1 1.5e-07 31.4 0.1 2.5 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain rRNA_processing PF08524.11 EJS42293.1 - 0.15 12.1 0.9 0.28 11.2 0.9 1.4 1 1 0 1 1 1 0 rRNA processing RRN3 PF05327.11 EJS42293.1 - 1.7 7.1 5.9 2 6.9 5.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 EJS42293.1 - 4 7.9 27.0 0.14 12.5 15.6 2.3 1 1 1 2 2 2 0 Centromere protein B dimerisation domain Peptidase_C13 PF01650.18 EJS42294.1 - 4.3e-46 157.5 1.3 5.8e-46 157.1 1.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.22 EJS42294.1 - 0.0013 18.8 2.0 0.0038 17.2 2.0 1.7 1 1 0 1 1 1 1 Caspase domain ResIII PF04851.15 EJS42295.1 - 1.3e-26 93.6 1.5 6.4e-26 91.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EJS42295.1 - 1.5e-15 57.4 0.1 2.7e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS42295.1 - 3.7e-15 56.2 1.5 3.2e-13 50.0 0.1 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EJS42295.1 - 2.1e-08 34.1 0.5 2.1e-08 34.1 0.5 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EJS42295.1 - 2.7e-06 27.7 0.0 8.9e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 EJS42295.1 - 0.0026 17.0 0.1 0.0059 15.8 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 EJS42295.1 - 0.0043 16.3 0.0 0.0087 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EJS42295.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SNF2_N PF00176.23 EJS42296.1 - 1.2e-66 224.8 0.3 2.6e-66 223.7 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJS42296.1 - 7.6e-19 68.1 0.1 2.2e-17 63.4 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 EJS42296.1 - 7.2e-15 55.1 10.1 7.2e-15 55.1 10.1 3.6 2 1 1 3 3 3 1 HSA ResIII PF04851.15 EJS42296.1 - 2.5e-12 47.1 0.0 2.5e-12 47.1 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EJS42296.1 - 4.1e-06 26.7 0.0 1.2e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Top6b_C PF18000.1 EJS42297.1 - 0.0078 16.4 0.0 0.95 9.7 0.0 2.6 2 0 0 2 2 2 1 Type 2 DNA topoisomerase 6 subunit B C-terminal domain IBN_N PF03810.19 EJS42297.1 - 0.011 15.6 0.2 0.14 12.1 0.0 3.1 2 0 0 2 2 2 0 Importin-beta N-terminal domain Orbi_VP6 PF01516.16 EJS42297.1 - 0.06 12.9 0.5 0.094 12.2 0.5 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 Ribosomal_S15 PF00312.22 EJS42298.1 - 3e-29 101.1 0.3 3e-29 101.1 0.3 2.1 3 0 0 3 3 3 1 Ribosomal protein S15 DUF3487 PF11990.8 EJS42298.1 - 0.058 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) MatE PF01554.18 EJS42299.1 - 3.2e-62 208.9 34.1 7.2e-42 142.8 7.7 2.8 3 0 0 3 3 3 2 MatE Nucleo_P87 PF07267.11 EJS42299.1 - 0.19 10.5 0.9 0.28 10.0 0.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Fcf1 PF04900.12 EJS42300.1 - 1.1e-34 118.7 0.2 1.9e-34 118.0 0.2 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EJS42300.1 - 2.7e-14 53.5 0.0 4.3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 EJS42300.1 - 0.018 15.4 0.2 0.037 14.3 0.0 1.6 2 0 0 2 2 2 0 NTF2 fold immunity protein tRNA-synt_1d PF00750.19 EJS42301.1 - 1.1e-122 409.3 6.8 1.4e-122 409.0 6.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EJS42301.1 - 4.8e-30 104.2 0.1 1.2e-28 99.7 0.0 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EJS42301.1 - 8e-11 42.4 0.0 4.7e-10 39.9 0.0 2.3 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF4393 PF14337.6 EJS42301.1 - 0.17 11.7 1.1 0.65 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) Amidase PF01425.21 EJS42302.1 - 1.4e-102 344.0 0.0 1.8e-102 343.7 0.0 1.1 1 0 0 1 1 1 1 Amidase SLX9 PF15341.6 EJS42302.1 - 0.56 10.6 3.4 0.96 9.8 3.4 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DEAD PF00270.29 EJS42303.1 - 3e-46 157.4 0.3 4.8e-45 153.5 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS42303.1 - 1.3e-30 106.0 0.1 5.8e-30 103.9 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS42303.1 - 2.6e-06 27.6 0.0 7.4e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EJS42303.1 - 0.026 13.7 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase TPR_1 PF00515.28 EJS42304.1 - 8.6e-21 72.8 2.7 1.3e-06 28.0 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EJS42304.1 - 7.8e-19 66.2 1.4 4.3e-05 23.3 0.1 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EJS42304.1 - 1.7e-16 59.6 0.1 2.2e-06 27.3 0.1 4.9 3 1 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 EJS42304.1 - 3.5e-16 58.5 0.5 0.0006 20.4 0.2 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EJS42304.1 - 9.2e-14 50.4 2.4 0.0082 16.3 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EJS42304.1 - 1e-12 48.5 0.5 0.00018 22.1 0.2 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EJS42304.1 - 5.5e-12 45.2 3.7 0.0078 16.5 0.1 5.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EJS42304.1 - 6.3e-11 42.6 1.3 0.031 14.8 0.1 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 EJS42304.1 - 5.8e-10 39.2 0.0 0.001 19.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 EJS42304.1 - 1e-06 28.9 0.1 0.7 10.3 0.0 4.1 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EJS42304.1 - 2.9e-06 27.6 0.1 3.6 8.4 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJS42304.1 - 0.00011 22.4 1.1 0.05 13.9 0.2 3.7 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EJS42304.1 - 0.00087 18.6 0.4 0.28 10.3 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 EJS42304.1 - 0.01 16.3 0.3 0.1 13.1 0.0 2.5 2 1 1 3 3 3 0 Bacterial transcriptional activator domain DUF2989 PF11207.8 EJS42304.1 - 0.013 15.3 0.1 0.033 13.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) TPR_7 PF13176.6 EJS42304.1 - 0.054 13.6 0.0 3.7 7.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_4 PF12763.7 EJS42304.1 - 0.078 12.9 0.2 0.53 10.3 0.1 2.4 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Glyco_transf_34 PF05637.12 EJS42305.1 - 2e-80 270.0 0.1 2.5e-80 269.6 0.1 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 EJS42305.1 - 0.007 16.4 0.2 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Sybindin PF04099.12 EJS42306.1 - 7.5e-35 119.9 3.8 1.3e-13 51.1 0.4 3.1 3 0 0 3 3 3 3 Sybindin-like family Sedlin_N PF04628.13 EJS42306.1 - 3.4e-06 27.2 1.7 6.5e-06 26.3 1.7 1.7 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region TraU PF06834.11 EJS42306.1 - 0.13 11.5 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 TraU protein Pkinase PF00069.25 EJS42307.1 - 7.9e-47 159.8 1.5 1e-40 139.8 0.3 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42307.1 - 2.3e-21 76.3 0.1 1.4e-19 70.4 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EJS42307.1 - 2e-07 30.6 0.0 3.9e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EJS42307.1 - 0.008 16.1 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Aha1_N PF09229.11 EJS42308.1 - 9.1e-36 123.1 0.6 2.2e-35 121.8 0.1 1.9 2 1 1 3 3 3 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EJS42308.1 - 5.2e-11 42.9 0.1 8.6e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF515 PF04415.12 EJS42308.1 - 0.021 13.2 3.2 0.031 12.7 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CRC_subunit PF08624.10 EJS42308.1 - 0.066 13.6 0.0 0.7 10.3 0.0 2.2 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit zf-C2H2 PF00096.26 EJS42309.1 - 1.1e-10 41.4 10.6 2.9e-05 24.3 2.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJS42309.1 - 1e-05 25.7 10.6 5.3e-05 23.4 6.8 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJS42309.1 - 1.3e-05 25.6 9.7 0.013 16.3 2.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EJS42309.1 - 3.5e-05 24.0 3.3 0.017 15.5 0.7 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Transmemb_17 PF09799.9 EJS42309.1 - 0.076 13.6 0.2 0.18 12.4 0.2 1.6 1 0 0 1 1 1 0 Predicted membrane protein DrsE_2 PF13686.6 EJS42309.1 - 0.14 12.0 0.0 0.55 10.1 0.0 1.9 1 1 0 1 1 1 0 DsrE/DsrF/DrsH-like family zf-C2H2_jaz PF12171.8 EJS42309.1 - 0.56 10.6 4.3 0.21 11.9 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 EJS42309.1 - 1 9.0 5.9 1.7 8.3 0.3 2.6 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain F-box PF00646.33 EJS42310.1 - 5.7e-07 29.3 0.2 1.5e-06 27.9 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EJS42310.1 - 6.1e-06 26.0 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EJS42310.1 - 0.0027 17.6 0.1 0.0047 16.8 0.1 1.4 1 0 0 1 1 1 1 F-box MPDZ_u10 PF16667.5 EJS42310.1 - 2.9 8.9 5.4 2.7 9.0 1.7 2.9 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein Svf1 PF08622.10 EJS42311.1 - 2.9e-41 141.3 0.1 4.7e-41 140.6 0.1 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 EJS42311.1 - 1.1e-39 135.9 1.0 5.7e-39 133.6 1.0 2.1 1 1 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain HNH PF01844.23 EJS42311.1 - 0.0023 18.1 0.0 0.0069 16.5 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Histone PF00125.24 EJS42312.1 - 4.3e-19 69.2 3.8 6.1e-19 68.7 3.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EJS42312.1 - 7.8e-06 26.1 0.1 1.6e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EJS42312.1 - 0.0016 18.9 0.0 0.0027 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 EJS42312.1 - 0.025 14.8 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein YscO-like PF16789.5 EJS42312.1 - 0.036 14.1 0.5 0.043 13.8 0.5 1.1 1 0 0 1 1 1 0 YscO-like protein DUF1018 PF06252.12 EJS42312.1 - 0.1 13.6 1.3 0.15 13.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Histone_H2A_C PF16211.5 EJS42313.1 - 5.5e-21 74.0 1.3 8.9e-21 73.3 1.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EJS42313.1 - 1.2e-17 64.5 0.0 1.7e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EJS42313.1 - 7.4e-06 26.2 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 EJS42313.1 - 0.053 13.5 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 LcrG protein ADK PF00406.22 EJS42314.1 - 8.2e-61 204.5 0.0 9.9e-61 204.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EJS42314.1 - 6.5e-23 81.7 0.2 1.9e-22 80.1 0.0 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 EJS42314.1 - 5.7e-17 61.4 0.0 1.3e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 EJS42314.1 - 3.7e-07 30.4 0.0 8.8e-07 29.2 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EJS42314.1 - 2.3e-06 28.2 0.0 4.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EJS42314.1 - 0.011 16.1 0.0 0.034 14.4 0.0 1.8 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 EJS42314.1 - 0.041 13.6 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_22 PF13401.6 EJS42314.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain MalF_P2 PF14785.6 EJS42315.1 - 0.035 14.1 0.3 0.079 13.0 0.3 1.5 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain BMFP PF04380.13 EJS42315.1 - 0.14 12.7 3.2 0.23 12.0 1.6 2.2 2 1 0 2 2 2 0 Membrane fusogenic activity DUF3767 PF12597.8 EJS42316.1 - 4.4e-36 122.8 0.1 4.4e-36 122.8 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3767) SOSSC PF15925.5 EJS42316.1 - 3.9 8.8 8.9 21 6.5 0.3 2.3 2 0 0 2 2 2 0 SOSS complex subunit C Aminotran_1_2 PF00155.21 EJS42317.1 - 3.2e-73 247.0 0.3 1.5e-72 244.8 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EJS42317.1 - 2.5e-08 32.9 0.0 2.5e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EJS42317.1 - 0.00014 21.0 0.0 0.00032 19.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EJS42317.1 - 0.001 18.5 0.9 0.014 14.8 0.9 2.2 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_60s PF00428.19 EJS42317.1 - 1.5 9.5 9.3 3.9 8.1 9.3 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Aconitase PF00330.20 EJS42318.1 - 2.4e-111 373.0 0.1 2.3e-110 369.7 0.1 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EJS42318.1 - 4.1e-38 130.7 0.1 1e-37 129.4 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain Ribosomal_S17 PF00366.20 EJS42318.1 - 0.098 12.8 1.8 4.9 7.3 0.1 2.7 3 0 0 3 3 3 0 Ribosomal protein S17 DUF1667 PF07892.11 EJS42318.1 - 0.12 12.5 0.2 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1667) Flavokinase PF01687.17 EJS42319.1 - 1.3e-26 93.1 0.0 1.8e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_L5_C PF00673.21 EJS42320.1 - 1e-29 102.6 0.1 4.3e-29 100.5 0.0 2.0 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EJS42320.1 - 4.7e-11 42.8 0.0 9.2e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Adaptin_N PF01602.20 EJS42321.1 - 2e-119 399.6 11.2 3.2e-119 398.9 11.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EJS42321.1 - 9.8e-54 180.8 0.1 3.7e-53 178.9 0.0 2.1 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EJS42321.1 - 1.4e-52 177.4 1.9 1.8e-52 177.0 0.2 2.1 2 0 0 2 2 2 1 Coatomer beta C-terminal region Cnd1 PF12717.7 EJS42321.1 - 4.1e-05 23.7 0.7 4.1e-05 23.7 0.7 4.0 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EJS42321.1 - 0.0032 17.8 3.7 2.1 8.8 0.0 4.7 2 1 2 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EJS42321.1 - 0.011 16.4 0.1 0.061 13.9 0.1 2.3 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region DUF5578 PF17741.1 EJS42321.1 - 0.039 13.4 8.8 2 7.8 0.1 3.5 2 2 1 4 4 4 0 Family of unknown function (DUF5578) FANCI_S2 PF14676.6 EJS42321.1 - 1.7 8.9 5.2 1.1 9.6 0.3 3.0 3 0 0 3 3 3 0 FANCI solenoid 2 Swi5 PF07061.11 EJS42322.1 - 0.0072 16.4 0.6 0.025 14.7 0.1 2.1 2 0 0 2 2 2 1 Swi5 zf-CCCH PF00642.24 EJS42323.1 - 2.5e-17 62.3 16.2 1.5e-08 34.3 6.6 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EJS42323.1 - 0.00036 20.5 19.3 0.036 14.1 3.3 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EJS42323.1 - 0.036 13.9 13.8 0.19 11.6 1.1 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 EJS42323.1 - 0.046 14.4 10.2 1.7 9.4 2.2 3.0 1 1 1 2 2 2 0 Torus domain SUR7 PF06687.12 EJS42323.1 - 0.062 12.9 0.2 0.08 12.6 0.2 1.5 1 1 0 1 1 1 0 SUR7/PalI family Defensin_int PF17858.1 EJS42323.1 - 0.23 11.4 0.7 0.49 10.4 0.7 1.5 1 0 0 1 1 1 0 Platypus intermediate defensin-like peptide zf-CCCH_2 PF14608.6 EJS42323.1 - 5 7.7 14.9 9 6.9 6.8 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RWD PF05773.22 EJS42324.1 - 6.2e-25 87.7 3.2 1.2e-24 86.8 3.2 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EJS42324.1 - 3.1e-05 24.4 4.8 3.1e-05 24.4 4.8 2.7 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 DUF4207 PF13904.6 EJS42324.1 - 0.0014 18.4 3.3 0.002 17.9 3.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) CENP-B_dimeris PF09026.10 EJS42324.1 - 1.3 9.4 7.5 0.21 12.0 2.1 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ENTH PF01417.20 EJS42325.1 - 1.7e-31 108.8 0.1 3.2e-31 108.0 0.1 1.5 1 0 0 1 1 1 1 ENTH domain Cas_Csy4 PF09618.10 EJS42325.1 - 0.00093 19.4 1.0 0.002 18.3 1.0 1.4 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csy4) SUIM_assoc PF16619.5 EJS42325.1 - 0.012 15.7 6.1 0.012 15.7 6.1 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2756 PF10956.8 EJS42325.1 - 0.22 12.0 5.9 0.62 10.6 5.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) PEHE PF15275.6 EJS42325.1 - 0.36 11.5 7.9 0.15 12.7 4.9 1.9 2 0 0 2 2 2 0 PEHE domain Spt5_N PF11942.8 EJS42325.1 - 1.7 9.7 22.9 1.9 9.5 7.6 2.9 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal BPL_N PF09825.9 EJS42325.1 - 3.2 6.7 5.8 5.1 6.1 5.8 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF3246 PF11596.8 EJS42325.1 - 7.2 6.0 23.4 9.2 5.6 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Pro_isomerase PF00160.21 EJS42326.1 - 6.8e-47 159.7 0.0 7.6e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 EJS42326.1 - 0.098 12.7 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Semialdhyde_dhC PF02774.18 EJS42327.1 - 4.4e-44 150.8 0.0 6.4e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EJS42327.1 - 3.2e-33 114.7 0.0 5.3e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 EJS42327.1 - 0.03 15.0 0.0 0.072 13.8 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 EJS42327.1 - 0.034 14.4 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AA_permease PF00324.21 EJS42328.1 - 2.7e-74 250.5 44.9 6.2e-73 246.0 44.9 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS42328.1 - 7.7e-30 104.1 40.5 9.1e-29 100.5 40.4 2.1 1 1 0 1 1 1 1 Amino acid permease Cytochrom_B_C PF00032.17 EJS42328.1 - 0.044 14.1 0.5 0.19 12.1 0.5 2.1 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD TPR_2 PF07719.17 EJS42329.1 - 2.1e-05 24.3 2.0 0.75 10.1 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJS42329.1 - 3.3e-05 23.5 0.2 0.56 10.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EJS42329.1 - 4.6e-05 23.0 1.5 1 9.1 0.1 3.5 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 EJS42329.1 - 0.00024 21.1 0.0 0.37 11.1 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EJS42329.1 - 0.002 18.3 0.3 0.12 12.7 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EJS42329.1 - 0.0027 18.2 0.8 0.58 10.7 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EJS42329.1 - 0.0038 17.9 0.0 3.7 8.6 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat SH3_1 PF00018.28 EJS42330.1 - 2.9e-13 49.2 0.0 6.5e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJS42330.1 - 2.5e-11 43.3 0.0 7.6e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJS42330.1 - 9.3e-06 25.2 0.0 2.6e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain DUF5599 PF18141.1 EJS42330.1 - 0.01 16.1 0.1 0.023 14.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5599) VEFS-Box PF09733.9 EJS42330.1 - 0.12 12.2 3.6 0.3 10.9 3.6 1.8 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Cwf_Cwc_15 PF04889.12 EJS42331.1 - 1e-15 58.2 18.8 2.1e-08 34.2 2.1 3.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein Sec1 PF00995.23 EJS42332.1 - 2.1e-98 331.0 6.5 2.5e-98 330.8 6.5 1.0 1 0 0 1 1 1 1 Sec1 family WD40 PF00400.32 EJS42333.1 - 1.2e-05 25.9 2.4 0.47 11.4 1.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.15 EJS42333.1 - 5e-05 22.8 0.5 0.0015 17.9 0.0 2.7 2 1 1 3 3 3 1 CPSF A subunit region Pro_isomerase PF00160.21 EJS42333.1 - 0.031 14.5 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sec5 PF15469.6 EJS42334.1 - 2.9e-50 170.7 15.4 9.7e-50 169.0 15.4 2.0 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 EJS42334.1 - 0.00049 20.1 3.9 0.00049 20.1 3.9 3.1 2 1 1 3 3 3 1 Vps51/Vps67 DUF2982 PF11201.8 EJS42334.1 - 0.034 13.7 0.0 0.12 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) COG2 PF06148.11 EJS42334.1 - 0.33 11.0 6.0 0.44 10.6 4.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TFIID_30kDa PF03540.13 EJS42335.1 - 6e-25 87.0 0.1 9.4e-25 86.3 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit GCP_N_terminal PF17681.1 EJS42335.1 - 0.088 12.4 0.2 0.11 12.0 0.2 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal CDC37_N PF03234.14 EJS42336.1 - 1e-42 146.1 7.7 1e-42 146.1 7.7 3.6 3 2 1 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EJS42336.1 - 8.6e-40 135.3 4.1 8.6e-40 135.3 4.1 2.3 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EJS42336.1 - 7e-26 90.3 6.4 7e-26 90.3 6.4 2.8 2 0 0 2 2 2 1 Cdc37 C terminal domain Endotoxin_N PF03945.14 EJS42336.1 - 0.0014 18.4 2.8 0.076 12.7 0.4 2.8 2 0 0 2 2 2 2 delta endotoxin, N-terminal domain Stb3 PF10330.9 EJS42337.1 - 2.1e-31 107.8 0.0 4.2e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Putative Sin3 binding protein IPK PF03770.16 EJS42338.1 - 7.2e-55 185.9 0.2 9e-55 185.6 0.2 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Bd3614-deam PF14439.6 EJS42338.1 - 1.1 9.3 3.1 2.2 8.3 3.1 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase HMG_box PF00505.19 EJS42339.1 - 2.9e-11 43.6 3.5 2.9e-11 43.6 3.5 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EJS42339.1 - 1.7e-08 34.9 2.4 1.7e-08 34.9 2.4 1.7 2 0 0 2 2 2 1 HMG-box domain Transketolase_N PF00456.21 EJS42339.1 - 0.014 14.4 0.5 0.019 13.9 0.5 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Protamine_like PF06382.11 EJS42339.1 - 0.02 15.1 0.1 0.02 15.1 0.1 1.4 2 0 0 2 2 2 0 Protamine and protamine like Alpha_adaptin_C PF02296.16 EJS42339.1 - 0.04 14.1 0.5 0.62 10.3 0.0 2.2 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain Ada3 PF10198.9 EJS42340.1 - 1.4e-43 148.2 3.7 1.4e-43 148.2 3.7 2.5 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 UQ_con PF00179.26 EJS42341.1 - 8.3e-45 151.9 0.0 1.1e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EJS42341.1 - 2.2e-30 104.2 1.3 3.6e-30 103.6 1.3 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain GGA_N-GAT PF18308.1 EJS42341.1 - 0.00054 19.5 3.3 0.081 12.6 0.2 2.4 2 0 0 2 2 2 2 GGA N-GAT domain Calsarcin PF05556.11 EJS42341.1 - 0.0067 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) RGS12_usC PF16612.5 EJS42341.1 - 0.027 14.9 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 DUF1421 PF07223.11 EJS42341.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) CybS PF05328.12 EJS42342.1 - 1.8e-50 170.1 0.0 2.2e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit BAH PF01426.18 EJS42343.1 - 0.035 14.0 0.5 0.045 13.6 0.5 1.3 1 0 0 1 1 1 0 BAH domain PXA PF02194.15 EJS42344.1 - 1.5e-12 47.9 0.3 3.6e-11 43.4 0.3 2.6 1 1 0 1 1 1 1 PXA domain Nipped-B_C PF12830.7 EJS42345.1 - 8.7e-31 107.3 1.4 8.7e-31 107.3 1.4 4.5 5 0 0 5 5 5 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EJS42345.1 - 1.3e-14 54.2 4.3 2.5e-14 53.2 1.2 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EJS42345.1 - 0.0024 18.0 2.7 42 4.8 0.1 5.6 5 0 0 5 5 5 0 HEAT repeat HHH_7 PF14635.6 EJS42345.1 - 0.0053 17.1 0.3 0.027 14.8 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif MetOD1 PF18546.1 EJS42345.1 - 0.023 14.7 4.1 11 5.9 0.1 4.1 3 0 0 3 3 3 0 Metanogen output domain 1 SAS4 PF15460.6 EJS42346.1 - 9.6e-29 99.4 6.8 9.6e-29 99.4 6.8 3.1 3 1 0 3 3 3 1 Something about silencing, SAS, complex subunit 4 PI3K_1B_p101 PF10486.9 EJS42346.1 - 0.066 11.0 10.2 0.003 15.4 3.8 1.7 1 1 1 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Metallophos PF00149.28 EJS42347.1 - 1.5e-11 45.1 0.9 2.7e-11 44.4 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Orf78 PF06024.12 EJS42347.1 - 0.0094 16.2 0.6 3.1 8.1 0.1 2.4 2 0 0 2 2 2 2 Orf78 (ac78) SARAF PF06682.12 EJS42347.1 - 0.098 12.3 1.0 0.56 9.8 0.1 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CrgA PF06781.12 EJS42347.1 - 0.11 12.6 6.6 0.58 10.2 1.3 3.0 3 0 0 3 3 3 0 Cell division protein CrgA DUF2956 PF11169.8 EJS42347.1 - 0.32 11.2 3.7 1.7 8.8 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) GWT1 PF06423.12 EJS42347.1 - 8 6.6 7.0 3.7 7.7 0.4 2.7 2 1 0 2 2 2 0 GWT1 PRELI PF04707.14 EJS42348.1 - 3.1e-56 189.5 0.4 3.8e-56 189.3 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family Cpn60_TCP1 PF00118.24 EJS42350.1 - 5.4e-160 533.2 0.9 6.1e-160 533.1 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sec1 PF00995.23 EJS42351.1 - 4.6e-120 402.6 10.4 6.6e-120 402.0 10.4 1.2 1 0 0 1 1 1 1 Sec1 family TIP49 PF06068.13 EJS42352.1 - 5.7e-169 561.9 0.6 7.1e-169 561.6 0.6 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EJS42352.1 - 9.5e-24 83.3 0.4 2.6e-23 81.9 0.4 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EJS42352.1 - 2.5e-08 34.4 1.1 8.5e-05 23.0 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EJS42352.1 - 2.4e-07 30.7 0.2 9.7e-05 22.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EJS42352.1 - 0.0011 19.3 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJS42352.1 - 0.013 15.9 2.5 3.7 7.9 0.2 2.6 2 1 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EJS42352.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_5 PF07728.14 EJS42352.1 - 0.021 14.8 0.2 0.82 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EJS42352.1 - 0.024 14.0 0.1 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EJS42352.1 - 0.04 14.3 0.7 0.15 12.4 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain CPT PF07931.12 EJS42352.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 EJS42352.1 - 0.071 12.4 0.1 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 EJS42352.1 - 0.12 12.1 0.0 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Nucleoporin_FG PF13634.6 EJS42353.1 - 0.095 13.6 139.9 0.25 12.2 30.4 6.1 1 1 4 5 5 5 0 Nucleoporin FG repeat region DEAD PF00270.29 EJS42354.1 - 6.3e-44 149.8 0.4 1.8e-41 141.8 0.1 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS42354.1 - 9.8e-26 90.3 1.5 7.9e-25 87.4 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS42354.1 - 1.3e-06 28.5 1.6 3.2e-06 27.2 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF2201 PF09967.9 EJS42354.1 - 0.0025 17.9 0.0 0.028 14.6 0.0 2.3 2 0 0 2 2 2 1 VWA-like domain (DUF2201) AAA_30 PF13604.6 EJS42354.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dockerin_1 PF00404.18 EJS42355.1 - 0.25 11.6 2.3 2.7 8.2 0.1 3.5 4 0 0 4 4 4 0 Dockerin type I domain CoaE PF01121.20 EJS42356.1 - 1.2e-66 223.8 0.0 1.4e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EJS42356.1 - 0.00015 22.3 0.1 0.00047 20.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EJS42356.1 - 0.0005 20.5 0.1 0.0056 17.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain SKI PF01202.22 EJS42356.1 - 0.0017 18.5 0.1 0.03 14.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 EJS42356.1 - 0.0019 18.4 0.1 0.016 15.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EJS42356.1 - 0.0023 18.2 0.0 0.0047 17.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EJS42356.1 - 0.0067 15.7 0.7 2.7 7.2 0.1 2.3 2 1 0 2 2 2 2 Zeta toxin Cytidylate_kin2 PF13189.6 EJS42356.1 - 0.013 15.6 0.1 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family PRK PF00485.18 EJS42356.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Abi_2 PF07751.11 EJS42356.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Abi-like protein Cytidylate_kin PF02224.18 EJS42356.1 - 0.11 12.2 0.1 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase ApbA_C PF08546.11 EJS42357.1 - 1.1e-19 70.8 0.0 2.1e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal FHA PF00498.26 EJS42358.1 - 4.6e-17 62.1 0.7 4.6e-17 62.1 0.7 3.3 3 1 1 4 4 4 1 FHA domain Yop-YscD_cpl PF16697.5 EJS42358.1 - 4.7e-05 23.6 0.9 0.00017 21.9 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FUSC PF04632.12 EJS42358.1 - 0.12 10.9 0.6 0.17 10.4 0.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EJS42358.1 - 8.1 5.9 15.1 1.7 8.1 11.2 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit DASH_Spc19 PF08287.11 EJS42359.1 - 1.1e-35 122.9 8.4 1.2e-35 122.7 8.4 1.0 1 0 0 1 1 1 1 Spc19 GP41 PF00517.17 EJS42359.1 - 0.087 12.7 1.4 0.81 9.6 0.1 2.3 2 1 0 2 2 2 0 Retroviral envelope protein Noelin-1 PF12308.8 EJS42359.1 - 0.18 11.8 3.6 5.1 7.1 0.2 2.9 2 1 0 2 2 2 0 Neurogenesis glycoprotein BLOC1_2 PF10046.9 EJS42359.1 - 0.36 11.1 9.7 12 6.3 0.1 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad2 PF08654.10 EJS42359.1 - 0.62 10.5 12.2 5.3 7.5 2.8 3.3 3 0 0 3 3 3 0 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 EJS42359.1 - 0.68 9.8 8.2 5.2 6.9 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 Laminin_II PF06009.12 EJS42359.1 - 5.7 7.0 8.8 2.1 8.4 0.2 2.9 2 1 0 2 2 2 0 Laminin Domain II Fib_alpha PF08702.10 EJS42359.1 - 9.5 6.4 10.0 22 5.2 5.4 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Rogdi_lz PF10259.9 EJS42360.1 - 1.7e-61 208.0 2.9 2e-61 207.8 2.9 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Cation_efflux PF01545.21 EJS42361.1 - 1.9e-43 148.5 13.1 1.9e-43 148.5 13.1 2.7 3 1 0 3 3 3 1 Cation efflux family DUF1772 PF08592.11 EJS42361.1 - 0.016 15.5 2.8 1.1 9.5 1.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) UreE_C PF05194.12 EJS42361.1 - 2.9 8.4 14.7 5.6 7.5 5.6 2.5 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain EST1_DNA_bind PF10373.9 EJS42362.1 - 1.7e-39 136.0 1.6 1.7e-39 136.0 1.6 1.9 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EJS42362.1 - 1.2e-18 68.1 0.1 4.3e-18 66.3 0.1 2.0 1 0 0 1 1 1 1 Telomerase activating protein Est1 Zn_clus PF00172.18 EJS42363.1 - 5.3e-09 36.0 8.5 1e-08 35.2 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1067 PF06362.11 EJS42363.1 - 1.6 9.5 11.7 1.7 9.5 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1067) PIP5K PF01504.18 EJS42364.1 - 8.3e-94 313.8 2.1 8.3e-94 313.8 2.1 2.2 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase CYSTM PF12734.7 EJS42365.1 - 1.2e-07 32.0 63.5 0.46 10.8 49.7 4.5 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Pro-rich PF15240.6 EJS42365.1 - 0.27 11.5 19.7 0.34 11.2 19.7 1.2 1 0 0 1 1 1 0 Proline-rich W2 PF02020.18 EJS42366.1 - 1.7e-15 56.9 2.6 4.3e-15 55.6 2.6 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EJS42366.1 - 4.2e-11 42.1 16.4 0.00064 19.4 0.8 3.8 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EJS42366.1 - 5.6e-09 36.0 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 EJS42366.1 - 4.4e-07 28.5 1.3 7.3e-07 27.7 0.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 EJS42366.1 - 0.0091 16.4 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EJS42366.1 - 0.018 14.0 2.7 0.045 12.7 2.7 1.6 1 1 0 1 1 1 0 L-fucokinase CTP_transf_3 PF02348.19 EJS42366.1 - 0.14 12.0 1.7 1.2 9.0 0.0 2.5 2 1 0 2 2 2 0 Cytidylyltransferase Hexapep_2 PF14602.6 EJS42366.1 - 4.8 7.0 17.0 3 7.7 3.4 4.1 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase Cpn60_TCP1 PF00118.24 EJS42367.1 - 5.1e-152 506.9 12.9 5.8e-152 506.7 12.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 EJS42367.1 - 0.074 12.5 0.1 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Telomere recombination Fungal_trans_2 PF11951.8 EJS42368.1 - 2.4e-12 46.4 0.3 2.4e-12 46.4 0.3 2.8 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS42368.1 - 4.4e-08 33.1 10.5 7.2e-08 32.4 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cg6151-P PF10233.9 EJS42369.1 - 1.4e-38 131.7 15.4 1.8e-38 131.4 15.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P ATG22 PF11700.8 EJS42369.1 - 0.0077 14.9 7.4 0.0093 14.6 7.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Gaa1 PF04114.14 EJS42369.1 - 0.0083 15.2 0.2 0.012 14.6 0.2 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Colicin PF01024.19 EJS42369.1 - 3.4 7.5 7.5 0.69 9.8 1.8 2.0 1 1 1 2 2 2 0 Colicin pore forming domain IncE PF17627.2 EJS42369.1 - 5.2 7.1 9.6 0.74 9.8 2.5 2.1 2 0 0 2 2 2 0 Inclusion membrane protein E HMG_box PF00505.19 EJS42370.1 - 2.1e-36 124.1 7.8 4.9e-21 74.9 1.2 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EJS42370.1 - 8.5e-17 61.5 4.4 5e-11 43.0 0.7 2.2 2 0 0 2 2 2 2 HMG-box domain Protamine_like PF06382.11 EJS42370.1 - 0.011 15.9 1.0 0.26 11.5 1.1 2.1 1 1 0 1 1 1 0 Protamine and protamine like PilJ_C PF18223.1 EJS42370.1 - 0.021 15.3 2.6 0.9 10.1 0.1 2.3 1 1 0 2 2 2 0 Pili PilJ C-terminal domain CHDNT PF08073.12 EJS42370.1 - 0.055 13.4 0.2 6.8 6.7 0.0 2.7 3 0 0 3 3 3 0 CHDNT (NUC034) domain Syntaxin_2 PF14523.6 EJS42370.1 - 0.21 12.0 2.3 14 6.1 0.2 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Cyt-b5 PF00173.28 EJS42371.1 - 2.8e-16 59.4 0.0 4.1e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain dsDNA_bind PF01984.20 EJS42372.1 - 1.7e-22 79.8 0.5 2e-22 79.5 0.5 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.9 EJS42372.1 - 0.46 11.0 0.1 0.46 11.0 0.1 3.3 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Cnd1 PF12717.7 EJS42373.1 - 1.5e-06 28.3 9.3 0.00035 20.7 2.0 5.2 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 SAM_KSR1 PF13543.6 EJS42373.1 - 0.14 12.3 1.9 6.4 6.9 0.0 3.4 3 0 0 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 Snf7 PF03357.21 EJS42374.1 - 9.1e-41 139.3 11.4 1.2e-40 138.9 11.4 1.1 1 0 0 1 1 1 1 Snf7 SlyX PF04102.12 EJS42374.1 - 0.083 13.5 0.7 0.083 13.5 0.7 3.0 4 0 0 4 4 4 0 SlyX T2SSS_2 PF16549.5 EJS42374.1 - 0.087 12.8 0.4 0.19 11.8 0.3 1.6 1 1 0 1 1 1 0 Type II secretion system (T2SS) pilotin, S protein HHH_2 PF12826.7 EJS42374.1 - 0.13 12.4 0.4 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4407 PF14362.6 EJS42374.1 - 0.37 10.1 3.3 0.38 10.0 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TSNAXIP1_N PF15739.5 EJS42374.1 - 0.48 10.8 7.2 0.36 11.2 3.4 2.4 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus Fib_alpha PF08702.10 EJS42374.1 - 0.59 10.3 15.5 1.5 9.0 4.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SKA1 PF07160.12 EJS42374.1 - 0.7 9.7 10.8 0.088 12.6 4.5 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF948 PF06103.11 EJS42374.1 - 0.81 10.0 5.9 0.67 10.3 1.4 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) BORCS7 PF16088.5 EJS42374.1 - 3.2 8.1 7.1 28 5.0 0.4 2.8 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 BRE1 PF08647.11 EJS42374.1 - 4.9 7.3 15.8 2.7 8.1 0.7 3.5 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase AAA PF00004.29 EJS42375.1 - 4.2e-11 43.4 0.0 1.7e-10 41.4 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EJS42375.1 - 2e-06 27.8 2.7 5.9e-05 23.1 0.3 3.0 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EJS42375.1 - 0.00037 20.9 0.0 0.0009 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EJS42375.1 - 0.0004 20.2 0.0 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EJS42375.1 - 0.0021 18.3 0.0 0.056 13.7 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EJS42375.1 - 0.0035 17.6 0.0 0.012 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 EJS42375.1 - 0.0054 16.8 0.4 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EJS42375.1 - 0.029 14.5 0.0 0.078 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EJS42375.1 - 0.031 14.1 3.8 0.055 13.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EJS42375.1 - 0.06 13.3 0.1 0.5 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EJS42375.1 - 0.11 12.9 0.4 0.88 10.0 0.0 2.7 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.6 EJS42375.1 - 0.12 12.7 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EJS42375.1 - 4.4 7.8 6.8 7.7 7.0 0.0 4.0 5 0 0 5 5 5 0 ABC transporter UPF1_Zn_bind PF09416.10 EJS42376.1 - 2.4e-64 215.9 7.8 2.4e-64 215.9 7.8 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EJS42376.1 - 4e-57 193.1 0.0 7.5e-57 192.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EJS42376.1 - 1.3e-47 162.8 8.8 1.3e-26 94.0 0.4 2.6 2 1 1 3 3 3 2 AAA domain DUF5599 PF18141.1 EJS42376.1 - 3.4e-27 94.5 0.0 7.2e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EJS42376.1 - 2.4e-17 63.3 0.1 4.5e-15 55.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJS42376.1 - 3.3e-13 50.2 0.1 6.5e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EJS42376.1 - 4.8e-05 22.8 0.1 0.0024 17.2 0.0 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EJS42376.1 - 5.6e-05 23.0 0.0 0.63 9.7 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EJS42376.1 - 0.00017 21.7 1.1 0.00034 20.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EJS42376.1 - 0.004 17.0 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 EJS42376.1 - 0.0058 15.9 0.0 0.74 8.9 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase PhoH PF02562.16 EJS42376.1 - 0.011 15.2 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 EJS42376.1 - 0.057 12.5 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein HEM4 PF02602.15 EJS42376.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD AAA_22 PF13401.6 EJS42376.1 - 0.093 13.0 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EJS42376.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-ribbon_3 PF13248.6 EJS42376.1 - 3.3 7.2 7.8 0.8 9.2 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain MBR1 PF17058.5 EJS42377.1 - 5.2e-50 170.7 8.7 5.2e-50 170.7 8.7 2.5 2 1 0 2 2 2 1 Mitochondrial biogenesis regulation protein 1 ADH_N PF08240.12 EJS42378.1 - 1.5e-30 105.3 0.3 2.6e-30 104.5 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJS42378.1 - 1.1e-24 86.8 0.1 1.8e-24 86.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJS42378.1 - 3.4e-06 28.2 0.0 5.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Rotamase PF00639.21 EJS42379.1 - 0.028 15.4 0.1 0.23 12.4 0.1 2.7 1 0 0 1 1 1 0 PPIC-type PPIASE domain EF-hand_14 PF17959.1 EJS42379.1 - 0.068 13.5 0.0 0.27 11.6 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Peptidase_M41 PF01434.18 EJS42380.1 - 3e-67 226.2 0.8 7e-67 225.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 EJS42380.1 - 4.1e-42 143.7 0.0 1.3e-41 142.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS42380.1 - 2.9e-15 55.8 0.2 2.1e-14 53.0 0.1 2.5 3 0 0 3 3 3 1 AAA+ lid domain FtsH_ext PF06480.15 EJS42380.1 - 4.5e-09 36.6 2.1 6.9e-09 36.0 0.5 2.2 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 EJS42380.1 - 0.0018 18.3 0.0 0.007 16.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EJS42380.1 - 0.0018 18.7 0.3 0.0093 16.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EJS42380.1 - 0.0018 18.0 0.0 0.0048 16.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EJS42380.1 - 0.0035 16.6 0.0 0.008 15.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EJS42380.1 - 0.0042 17.5 1.6 0.053 13.9 0.1 3.1 3 1 1 4 4 4 1 AAA ATPase domain AAA_2 PF07724.14 EJS42380.1 - 0.0046 17.1 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF2407_C PF13373.6 EJS42380.1 - 0.0046 17.1 0.2 0.011 15.9 0.2 1.6 1 0 0 1 1 1 1 DUF2407 C-terminal domain AAA_22 PF13401.6 EJS42380.1 - 0.027 14.7 0.1 0.68 10.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EJS42380.1 - 0.035 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EJS42380.1 - 0.1 12.8 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain RP-C_C PF11800.8 EJS42380.1 - 0.11 12.6 1.5 0.29 11.2 1.5 1.7 1 0 0 1 1 1 0 Replication protein C C-terminal region Neurochondrin PF05536.11 EJS42380.1 - 0.14 10.5 0.2 0.24 9.7 0.2 1.3 1 0 0 1 1 1 0 Neurochondrin SMBP PF16785.5 EJS42380.1 - 0.15 12.3 1.6 0.25 11.6 0.4 1.9 2 0 0 2 2 1 0 Small metal-binding protein DUF5100 PF17029.5 EJS42380.1 - 0.21 11.4 3.6 0.8 9.6 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5100) NAD_binding_10 PF13460.6 EJS42381.1 - 1.2e-46 158.9 0.0 1.4e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EJS42381.1 - 8.8e-09 34.8 0.7 1.3e-08 34.2 0.7 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EJS42381.1 - 1.3e-08 34.6 0.0 2.6e-08 33.6 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EJS42381.1 - 2.5e-08 33.8 0.1 5.1e-08 32.8 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EJS42381.1 - 2.2e-06 28.1 0.1 3.2e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EJS42381.1 - 2.4e-05 24.4 0.1 4.3e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 EJS42381.1 - 0.00026 21.1 0.4 0.00038 20.6 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EJS42381.1 - 0.0015 18.8 0.1 0.003 17.8 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 EJS42381.1 - 0.0077 15.7 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 EJS42381.1 - 0.011 15.7 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 EJS42381.1 - 0.016 14.3 0.1 0.03 13.4 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EJS42381.1 - 0.059 12.5 0.3 0.17 11.0 0.3 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein WD40 PF00400.32 EJS42382.1 - 4.1e-14 52.7 20.5 0.32 12.0 0.1 10.3 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS42382.1 - 8.7e-09 35.6 1.1 3.4 8.0 0.1 7.2 3 3 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJS42382.1 - 1e-06 28.8 0.4 0.32 10.8 0.0 4.0 3 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EJS42382.1 - 0.0024 17.3 1.3 0.013 14.9 0.8 2.2 1 1 1 2 2 2 1 WD40-like domain RAB3GAP2_N PF14655.6 EJS42382.1 - 0.0067 15.7 0.0 0.069 12.4 0.0 2.6 2 1 2 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus UTP15_C PF09384.10 EJS42383.1 - 2e-44 150.9 0.3 3.4e-44 150.1 0.3 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EJS42383.1 - 2.9e-17 62.7 5.0 0.031 15.2 0.2 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS42383.1 - 6e-07 29.7 0.0 0.12 12.7 0.0 5.1 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain FUR PF01475.19 EJS42384.1 - 0.017 15.3 1.4 5.7 7.1 0.0 3.1 3 0 0 3 3 3 0 Ferric uptake regulator family NOA36 PF06524.12 EJS42384.1 - 0.034 13.5 1.4 0.061 12.6 1.4 1.3 1 0 0 1 1 1 0 NOA36 protein SOR_SNZ PF01680.17 EJS42385.1 - 2.5e-106 354.1 5.6 3.2e-106 353.7 5.6 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EJS42385.1 - 1.1e-07 31.4 4.8 3.4e-07 29.8 0.2 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 EJS42385.1 - 0.0041 16.3 1.7 0.053 12.7 0.1 2.6 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.17 EJS42385.1 - 0.0044 16.2 1.8 0.43 9.6 0.0 2.9 2 2 1 3 3 3 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EJS42385.1 - 0.01 15.3 0.1 0.048 13.1 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein TMP-TENI PF02581.17 EJS42385.1 - 0.017 14.4 1.0 0.49 9.7 0.1 2.7 2 1 1 3 3 3 0 Thiamine monophosphate synthase TetR_C_27 PF17935.1 EJS42385.1 - 0.017 15.1 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain 1-cysPrx_C PF10417.9 EJS42385.1 - 0.055 13.3 0.6 2 8.3 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin IGPS PF00218.21 EJS42385.1 - 0.068 12.3 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.15 EJS42385.1 - 0.19 11.0 3.4 0.26 10.6 0.2 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase MMR_HSR1 PF01926.23 EJS42386.1 - 1.8e-14 53.8 0.1 7.6e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJS42386.1 - 2.9e-05 24.0 2.9 0.00079 19.4 2.9 2.2 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 EJS42386.1 - 0.00029 20.5 0.2 0.0006 19.4 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 EJS42386.1 - 0.00076 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 EJS42386.1 - 0.00081 19.3 0.1 0.0042 17.0 0.1 2.0 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 EJS42386.1 - 0.0059 16.9 0.6 0.18 12.0 0.0 3.0 4 0 0 4 4 3 1 AAA domain FeoB_N PF02421.18 EJS42386.1 - 0.0059 16.1 0.8 0.082 12.4 0.2 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_24 PF13479.6 EJS42386.1 - 0.0082 15.9 0.1 0.029 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EJS42386.1 - 0.0086 16.1 0.4 2.2 8.3 0.0 2.8 2 1 1 3 3 3 1 Dynamin family Septin PF00735.18 EJS42386.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_18 PF13238.6 EJS42386.1 - 0.012 16.2 0.5 0.051 14.1 0.1 2.2 3 0 0 3 3 3 0 AAA domain KTI12 PF08433.10 EJS42386.1 - 0.012 15.1 0.0 0.042 13.3 0.0 1.8 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AIG1 PF04548.16 EJS42386.1 - 0.019 14.3 0.1 0.31 10.3 0.0 2.3 2 0 0 2 2 2 0 AIG1 family MeaB PF03308.16 EJS42386.1 - 0.025 13.6 0.1 0.19 10.7 0.0 2.0 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 EJS42386.1 - 0.039 13.7 0.0 1.1 9.0 0.0 2.5 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 EJS42386.1 - 0.047 14.2 1.2 0.061 13.8 0.5 1.7 1 1 0 1 1 1 0 AAA domain IIGP PF05049.13 EJS42386.1 - 0.057 12.5 1.4 0.07 12.2 0.1 1.7 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_25 PF13481.6 EJS42386.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EJS42386.1 - 0.18 12.2 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Aldose_epim PF01263.20 EJS42387.1 - 1.6e-54 185.3 0.4 1.9e-54 185.0 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase BsuPI PF12690.7 EJS42387.1 - 0.052 13.6 0.2 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Intracellular proteinase inhibitor zf-MYND PF01753.18 EJS42388.1 - 8.4e-08 32.2 18.2 8.4e-08 32.2 18.2 1.9 2 1 0 2 2 2 1 MYND finger Arm PF00514.23 EJS42388.1 - 0.17 12.0 0.0 8.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Prenyltransf PF01255.19 EJS42389.1 - 2.3e-65 220.3 0.1 3e-65 219.9 0.1 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase KMP11 PF03037.16 EJS42389.1 - 0.084 13.7 0.0 0.28 12.0 0.0 1.9 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 WD40 PF00400.32 EJS42390.1 - 4.1e-18 65.4 14.0 9.7e-05 23.1 0.0 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS42390.1 - 7.6e-07 29.4 0.1 0.35 11.2 0.0 4.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJS42390.1 - 0.012 14.7 0.0 0.056 12.4 0.0 2.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TF_Zn_Ribbon PF08271.12 EJS42390.1 - 0.074 12.6 1.6 0.2 11.2 1.6 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding PGM_PMM_I PF02878.16 EJS42391.1 - 2.5e-37 127.6 0.1 4.4e-37 126.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EJS42391.1 - 5e-27 94.4 0.0 8.3e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EJS42391.1 - 9.2e-14 51.9 0.0 2.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EJS42391.1 - 2e-05 24.7 0.0 4.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.25 EJS42392.1 - 6.9e-68 228.9 4.8 5.1e-66 222.7 2.6 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42392.1 - 1.7e-41 142.2 0.6 8.8e-40 136.6 0.6 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EJS42392.1 - 5.6e-18 64.5 0.0 1.1e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 EJS42392.1 - 4.6e-07 29.4 0.0 8.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EJS42392.1 - 8.3e-05 21.7 1.4 0.0057 15.7 0.1 2.5 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 EJS42392.1 - 0.0004 20.4 0.0 0.18 11.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EJS42392.1 - 0.00071 19.0 0.2 0.0014 18.0 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EJS42392.1 - 0.0015 17.4 2.2 0.0044 15.9 0.0 2.5 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EJS42392.1 - 0.069 12.7 0.3 0.21 11.2 0.3 1.8 1 0 0 1 1 1 0 RIO1 family HLH PF00010.26 EJS42393.1 - 0.027 14.4 0.5 0.047 13.7 0.5 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain EPSP_synthase PF00275.20 EJS42394.1 - 3.1e-149 497.2 0.0 5e-149 496.5 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EJS42394.1 - 2.8e-98 328.2 0.1 4.9e-98 327.5 0.1 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EJS42394.1 - 3.5e-58 197.6 0.0 1.2e-57 195.8 0.0 1.9 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 EJS42394.1 - 1e-36 126.5 0.1 3.3e-36 124.8 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EJS42394.1 - 1.9e-22 79.3 0.0 6e-22 77.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EJS42394.1 - 4.4e-10 39.2 0.3 8.4e-10 38.3 0.3 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EJS42394.1 - 1.2e-07 31.9 0.0 4.4e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 EJS42394.1 - 5e-06 26.4 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.6 EJS42394.1 - 0.0002 21.5 0.0 0.00097 19.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EJS42394.1 - 0.014 15.4 0.0 0.046 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain THF_DHG_CYH PF00763.23 EJS42394.1 - 0.048 13.9 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Sacchrp_dh_NADP PF03435.18 EJS42394.1 - 0.061 13.6 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 6PF2K PF01591.18 EJS42394.1 - 0.063 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase FIN1 PF17300.2 EJS42395.1 - 1.6e-100 335.6 15.9 1.8e-100 335.4 15.9 1.0 1 0 0 1 1 1 1 Filaments in between nuclei protein-1 BTB_2 PF02214.22 EJS42396.1 - 1.7e-08 34.7 0.2 6.8e-05 23.1 0.1 3.0 2 1 0 2 2 2 2 BTB/POZ domain Rgp1 PF08737.10 EJS42397.1 - 2.6e-107 359.6 6.8 2.6e-107 359.6 6.8 1.9 2 0 0 2 2 2 1 Rgp1 IATP PF04568.12 EJS42397.1 - 0.24 11.9 1.7 0.42 11.1 0.8 1.9 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP MTS PF05175.14 EJS42398.1 - 8.7e-09 35.1 0.0 7.3e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EJS42398.1 - 0.0012 18.3 0.1 0.0027 17.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EJS42398.1 - 0.0026 17.6 0.0 0.04 13.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJS42398.1 - 0.0037 17.9 0.0 0.14 12.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EJS42398.1 - 0.0044 17.0 0.0 0.73 9.7 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain UPF0020 PF01170.18 EJS42398.1 - 0.12 12.1 0.0 1.8 8.2 0.0 2.0 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 EJS42398.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein PRMT5 PF05185.16 EJS42398.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Dopey_N PF04118.14 EJS42399.1 - 9.4e-113 376.4 0.9 9.4e-113 376.4 0.9 3.1 3 0 0 3 3 3 1 Dopey, N-terminal Choline_kinase PF01633.20 EJS42400.1 - 2.9e-61 206.7 1.7 4.1e-61 206.3 1.7 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EJS42400.1 - 3.7e-14 52.1 0.1 7.8e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EJS42400.1 - 1.9e-11 44.3 0.2 4.4e-11 43.2 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EJS42400.1 - 3.5e-08 33.1 1.1 5.3e-08 32.5 1.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EJS42400.1 - 0.00022 20.2 0.1 0.00034 19.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) 2-oxoacid_dh PF00198.23 EJS42401.1 - 5.3e-80 268.2 0.0 7.3e-80 267.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EJS42401.1 - 2.2e-15 56.2 0.3 4e-15 55.4 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 EJS42401.1 - 0.00034 21.3 0.1 0.0022 18.7 0.1 2.1 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.19 EJS42401.1 - 0.00099 19.0 0.1 0.0032 17.3 0.1 1.8 1 1 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 EJS42401.1 - 0.0012 18.7 0.0 0.059 13.2 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 EJS42401.1 - 0.041 13.9 0.0 0.17 11.9 0.0 2.0 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Mitofilin PF09731.9 EJS42401.1 - 4 6.2 15.6 5.2 5.8 15.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PriC PF07445.12 EJS42402.1 - 0.0014 18.6 9.2 0.011 15.6 1.1 2.2 1 1 1 2 2 2 2 Primosomal replication protein priC Mad3_BUB1_II PF08171.11 EJS42402.1 - 0.0046 17.1 1.6 0.033 14.4 0.2 2.5 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Med30 PF11315.8 EJS42402.1 - 0.017 15.3 0.5 0.017 15.3 0.5 1.9 2 1 0 2 2 2 0 Mediator complex subunit 30 CDC37_N PF03234.14 EJS42402.1 - 0.024 15.5 3.3 0.077 13.9 0.2 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding LRRC37AB_C PF14914.6 EJS42402.1 - 0.047 13.6 0.3 0.047 13.6 0.3 1.9 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Sporozoite_P67 PF05642.11 EJS42402.1 - 0.46 8.5 1.7 0.55 8.3 0.7 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen RecG_N PF17190.4 EJS42402.1 - 0.66 10.7 9.7 0.17 12.6 2.3 2.8 1 1 1 3 3 3 0 RecG N-terminal helical domain CENP-H PF05837.12 EJS42402.1 - 1.1 9.7 4.9 1.7 9.1 1.1 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 EJS42402.1 - 1.4 9.4 12.7 0.21 12.1 1.9 3.2 4 0 0 4 4 4 0 Cell division protein ZapB Bul1_C PF04426.12 EJS42403.1 - 0.26 10.6 3.9 0.53 9.7 0.9 2.3 2 0 0 2 2 2 0 Bul1 C terminus V_ATPase_I PF01496.19 EJS42404.1 - 2.8e-299 994.7 6.0 3.5e-299 994.4 6.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CLZ PF16526.5 EJS42404.1 - 0.0041 17.4 5.3 0.1 13.0 0.9 2.6 2 0 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snapin_Pallidin PF14712.6 EJS42404.1 - 0.0059 17.0 7.2 0.64 10.5 0.8 3.4 4 0 0 4 4 4 2 Snapin/Pallidin DUF1043 PF06295.12 EJS42404.1 - 0.083 12.9 0.2 0.21 11.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Bcr-Abl_Oligo PF09036.10 EJS42404.1 - 0.18 11.9 0.8 0.65 10.0 0.8 2.0 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Spc24 PF08286.11 EJS42404.1 - 0.32 11.2 2.6 1.6 9.0 0.2 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CdvA PF18822.1 EJS42404.1 - 0.54 10.1 3.3 0.69 9.8 0.3 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF948 PF06103.11 EJS42404.1 - 0.72 10.1 5.0 3.8 7.9 0.6 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GCN5L1 PF06320.13 EJS42404.1 - 0.78 9.9 3.2 16 5.7 0.2 2.6 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Prefoldin_2 PF01920.20 EJS42404.1 - 7.3 6.6 9.5 9.7 6.2 0.3 3.8 4 0 0 4 4 4 0 Prefoldin subunit RabGAP-TBC PF00566.18 EJS42405.1 - 1.3e-38 132.8 1.5 1.7e-38 132.5 1.5 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mito_carr PF00153.27 EJS42406.1 - 6.3e-68 224.8 4.8 9.9e-24 83.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 EJS42406.1 - 0.068 12.3 0.2 0.3 10.3 0.1 1.9 2 0 0 2 2 2 0 Fuseless Cu-oxidase_2 PF07731.14 EJS42407.1 - 2.7e-47 159.9 11.1 1e-41 141.9 0.8 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EJS42407.1 - 2.2e-42 143.8 7.2 2.6e-39 133.9 0.8 3.7 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 EJS42407.1 - 5.1e-36 124.2 10.8 4.3e-32 111.4 2.6 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EJS42407.1 - 0.13 12.4 0.0 14 5.8 0.0 3.3 3 0 0 3 3 3 0 Cupredoxin-like domain Tom37_C PF11801.8 EJS42408.1 - 1.3e-51 174.5 3.4 1.4e-51 174.3 1.9 1.7 2 0 0 2 2 2 1 Tom37 C-terminal domain Tom37 PF10568.9 EJS42408.1 - 3.5e-35 121.0 0.0 5.8e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EJS42408.1 - 0.0044 17.7 0.0 0.015 16.0 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain NinG PF05766.12 EJS42408.1 - 0.053 13.5 0.9 0.11 12.5 0.9 1.5 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein GST_N_2 PF13409.6 EJS42408.1 - 0.062 13.6 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EJS42408.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Suf PF05843.14 EJS42409.1 - 4e-66 224.0 21.1 1.4e-60 205.8 10.7 3.7 2 2 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_17 PF13431.6 EJS42409.1 - 0.079 13.4 0.5 1.5e+02 3.1 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ArgJ PF01960.18 EJS42410.1 - 7.5e-142 472.5 6.3 8.5e-142 472.3 6.3 1.0 1 0 0 1 1 1 1 ArgJ family SUR7 PF06687.12 EJS42411.1 - 9.7e-20 71.1 15.7 1.2e-19 70.8 15.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family Phage_holin_3_6 PF07332.11 EJS42411.1 - 0.0049 16.9 0.8 0.0049 16.9 0.8 1.9 3 0 0 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III ABC2_membrane PF01061.24 EJS42411.1 - 0.98 8.8 13.7 0.061 12.7 8.1 1.8 2 0 0 2 2 2 0 ABC-2 type transporter PPR_long PF17177.4 EJS42412.1 - 0.07 12.5 0.3 2.2 7.6 0.1 2.3 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP TUG-UBL1 PF11470.8 EJS42413.1 - 1.7e-21 76.2 2.9 2.5e-21 75.6 1.5 2.1 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EJS42413.1 - 6.8e-18 64.6 0.1 2.5e-17 62.9 0.1 2.0 1 0 0 1 1 1 1 UBX domain Type2_restr_D3 PF16902.5 EJS42413.1 - 0.68 9.9 2.8 45 4.1 0.1 3.2 3 0 0 3 3 3 0 Type-2 restriction enzyme D3 domain TAFII28 PF04719.14 EJS42414.1 - 6.9e-27 93.4 2.2 1.1e-23 83.1 0.8 2.8 2 0 0 2 2 2 2 hTAFII28-like protein conserved region ABC_membrane_2 PF06472.15 EJS42414.1 - 0.1 12.0 0.2 0.1 12.0 0.2 1.8 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 PBP1_TM PF14812.6 EJS42414.1 - 0.19 12.1 11.3 0.97 9.8 0.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_11 PF08241.12 EJS42415.1 - 4.3e-12 46.5 0.0 7.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS42415.1 - 1.1e-10 42.0 0.0 2.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJS42415.1 - 4.8e-06 27.2 0.0 1.1e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJS42415.1 - 9e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJS42415.1 - 5.6e-05 23.0 0.1 0.00018 21.3 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain EMP24_GP25L PF01105.24 EJS42416.1 - 1.4e-41 142.5 0.0 1.6e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TMEM191C PF15194.6 EJS42416.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 TMEM191C family Rad33 PF08730.10 EJS42417.1 - 4e-11 43.2 2.5 0.00013 22.0 0.1 2.1 1 1 1 2 2 2 2 Rad33 Spt5-NGN PF03439.13 EJS42418.1 - 1.3e-21 76.2 0.0 3.5e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EJS42418.1 - 1.9e-20 73.7 13.1 1.9e-20 73.7 13.1 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EJS42418.1 - 2.1e-15 56.0 8.3 0.00037 20.3 0.4 4.7 4 0 0 4 4 4 4 KOW motif CTD PF12815.7 EJS42418.1 - 0.00041 20.9 24.6 0.00041 20.9 24.6 3.6 2 2 0 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3912 PF13051.6 EJS42418.1 - 0.001 19.3 0.5 0.38 11.1 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) Nucleo_P87 PF07267.11 EJS42418.1 - 1.5 7.6 24.1 2.9 6.6 24.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_L33 PF00471.20 EJS42419.1 - 0.0002 21.7 0.1 0.00041 20.7 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L33 Sterol_MT_C PF08498.10 EJS42420.1 - 1.6e-26 92.4 2.0 2.6e-26 91.7 2.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EJS42420.1 - 1.1e-19 70.9 0.0 2.4e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS42420.1 - 7.4e-18 65.0 0.0 1.7e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJS42420.1 - 5.9e-16 58.6 0.1 1e-15 57.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EJS42420.1 - 2.8e-12 46.5 0.2 4e-12 46.0 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EJS42420.1 - 4.2e-12 46.2 0.0 6.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJS42420.1 - 1.5e-11 44.9 0.2 5e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJS42420.1 - 1.2e-08 34.6 0.0 1.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 EJS42420.1 - 3.1e-06 26.9 0.4 7.5e-06 25.6 0.4 1.6 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EJS42420.1 - 0.005 16.3 0.1 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EJS42420.1 - 0.01 15.1 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 EJS42420.1 - 0.022 14.8 0.3 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain N6_N4_Mtase PF01555.18 EJS42420.1 - 0.026 14.3 0.1 6.1 6.5 0.0 2.2 2 0 0 2 2 2 0 DNA methylase DOT1 PF08123.13 EJS42420.1 - 0.029 13.9 0.1 0.075 12.5 0.0 1.8 2 0 0 2 2 2 0 Histone methylation protein DOT1 PCMT PF01135.19 EJS42420.1 - 0.039 13.7 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EJS42420.1 - 0.095 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PAP1 PF08601.10 EJS42421.1 - 4.1e-20 72.8 3.4 4.1e-20 72.8 3.4 4.5 1 1 3 4 4 4 1 Transcription factor PAP1 bZIP_1 PF00170.21 EJS42421.1 - 1.1e-07 31.9 7.5 3e-07 30.4 7.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EJS42421.1 - 0.016 15.3 12.3 0.016 15.3 12.3 2.5 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 EJS42421.1 - 1.9 9.1 11.8 2.2 8.9 8.3 2.6 2 0 0 2 2 2 0 bZIP Maf transcription factor Glyoxalase PF00903.25 EJS42423.1 - 7.7e-37 126.3 0.0 7.8e-21 74.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EJS42423.1 - 6.6e-12 45.7 0.0 2.9e-06 27.5 0.0 3.6 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 EJS42423.1 - 4.2e-05 23.6 0.1 0.057 13.5 0.1 2.4 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_6 PF18029.1 EJS42423.1 - 0.00014 22.6 0.0 0.32 11.8 0.0 3.0 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EJS42423.1 - 0.00086 19.5 0.0 0.24 11.5 0.0 3.5 3 1 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EJS42423.1 - 0.0014 18.6 0.6 5.3 7.0 0.0 3.9 4 1 0 4 4 4 2 Glyoxalase-like domain ThiD2 PF17792.1 EJS42423.1 - 0.0045 17.4 0.0 0.87 10.1 0.0 2.2 2 0 0 2 2 2 1 ThiD2 family VPS9 PF02204.18 EJS42424.1 - 1.6e-09 37.9 0.2 5e-09 36.3 0.2 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EJS42424.1 - 1.3e-05 25.3 0.1 0.61 10.5 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJS42424.1 - 3.4e-05 24.3 0.4 0.094 13.3 0.0 3.7 1 1 3 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJS42424.1 - 0.066 13.8 0.3 8.6 7.3 0.1 4.1 4 0 0 4 4 4 0 Ankyrin repeat Ras PF00071.22 EJS42425.1 - 1.3e-56 190.6 0.3 1.6e-56 190.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS42425.1 - 3.5e-34 117.6 0.1 6.2e-34 116.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS42425.1 - 4.1e-15 55.7 0.0 4.7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EJS42425.1 - 2.4e-08 33.6 0.1 2.9e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EJS42425.1 - 9.5e-07 28.5 0.3 5.3e-05 22.8 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EJS42425.1 - 1.5e-06 28.3 0.0 3.7e-06 27.0 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EJS42425.1 - 6.1e-05 22.5 0.1 8.2e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EJS42425.1 - 0.00027 20.9 0.2 0.031 14.2 0.0 2.3 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EJS42425.1 - 0.0027 18.0 0.0 0.0043 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 EJS42425.1 - 0.0052 16.4 0.1 0.018 14.7 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EJS42425.1 - 0.011 16.1 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EJS42425.1 - 0.012 15.6 0.2 0.024 14.6 0.0 1.6 2 0 0 2 2 2 0 NTPase TniB PF05621.11 EJS42425.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 EJS42425.1 - 0.019 14.7 0.3 0.076 12.8 0.1 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EJS42425.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 EJS42425.1 - 0.029 13.9 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EJS42425.1 - 0.037 13.7 0.0 0.086 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EJS42425.1 - 0.073 13.2 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EJS42425.1 - 0.087 12.1 0.2 0.35 10.1 0.0 2.0 2 0 0 2 2 2 0 Septin Pkinase PF00069.25 EJS42426.1 - 1.7e-75 253.8 0.0 2.7e-75 253.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42426.1 - 4.1e-40 137.7 0.0 6.9e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EJS42426.1 - 1.9e-29 101.6 0.0 3.5e-16 59.1 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EJS42426.1 - 2e-07 30.6 0.0 1.5e-05 24.5 0.0 2.7 3 0 0 3 3 3 1 Kinase-like SH3_3 PF08239.11 EJS42426.1 - 0.0015 18.8 0.1 0.0043 17.3 0.1 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain Kdo PF06293.14 EJS42426.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EJS42426.1 - 0.069 12.1 0.0 0.069 12.1 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain DUF2076 PF09849.9 EJS42427.1 - 1.5e-06 28.5 7.8 1.8e-06 28.2 7.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EJS42427.1 - 9.3e-05 22.5 4.6 0.00014 21.9 4.6 1.3 1 0 0 1 1 1 1 CHCH domain TMEM65 PF10507.9 EJS42427.1 - 0.011 15.6 1.2 0.019 14.9 1.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 65 CX9C PF16860.5 EJS42427.1 - 2.9 8.0 7.7 0.15 12.1 2.4 1.6 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, SAP PF02037.27 EJS42428.1 - 1.9e-12 46.6 0.7 4.8e-12 45.3 0.6 1.7 2 0 0 2 2 2 1 SAP domain DsrH PF04077.12 EJS42428.1 - 0.081 13.1 0.0 3.4 7.9 0.0 2.6 2 1 0 2 2 2 0 DsrH like protein PX PF00787.24 EJS42429.1 - 2.3e-22 79.1 0.9 5.4e-22 77.9 0.1 2.0 2 0 0 2 2 2 1 PX domain IL5 PF02025.15 EJS42429.1 - 0.0084 16.4 0.0 0.15 12.4 0.1 2.6 2 0 0 2 2 2 1 Interleukin 5 TAF4 PF05236.14 EJS42430.1 - 1.5e-58 198.7 3.4 1.5e-58 198.7 3.4 1.8 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family TFIID_30kDa PF03540.13 EJS42430.1 - 0.015 15.3 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit DUF4590 PF15257.6 EJS42430.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) PLA2_B PF01735.18 EJS42431.1 - 1.5e-224 745.9 4.6 1.5e-224 745.9 4.6 1.4 2 0 0 2 2 2 1 Lysophospholipase catalytic domain IBR PF01485.21 EJS42431.1 - 0.016 15.4 0.7 0.032 14.4 0.7 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Apt1 PF10351.9 EJS42431.1 - 0.098 11.5 8.5 0.15 10.9 8.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PLA2_B PF01735.18 EJS42432.1 - 6.7e-231 766.9 4.2 8.2e-231 766.6 4.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 EJS42432.1 - 0.03 14.6 1.4 0.058 13.6 1.4 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain SR-25 PF10500.9 EJS42432.1 - 3.2 7.3 7.7 6.2 6.4 7.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ARD PF03079.14 EJS42433.1 - 1.5e-52 178.0 0.1 1.7e-52 177.8 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EJS42433.1 - 2.5e-10 39.9 0.0 4.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EJS42433.1 - 5.4e-08 32.8 0.0 8.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EJS42433.1 - 0.0088 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 EJS42433.1 - 0.026 14.2 0.0 0.084 12.6 0.0 1.7 1 1 1 2 2 2 0 Cupin-like domain SEO_N PF14576.6 EJS42434.1 - 0.083 12.0 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Sieve element occlusion N-terminus BUD22 PF09073.10 EJS42435.1 - 9.6e-84 282.2 36.9 1.5e-83 281.6 36.9 1.3 1 0 0 1 1 1 1 BUD22 p450 PF00067.22 EJS42436.1 - 7.1e-56 189.9 0.1 8.9e-56 189.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5314 PF17241.2 EJS42436.1 - 0.08 12.6 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5314) DHNA PF04038.12 EJS42436.1 - 0.083 13.4 0.2 9.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Dihydroneopterin aldolase KilA-N PF04383.13 EJS42437.1 - 7.4e-05 22.6 0.1 0.00087 19.1 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain Fungal_trans PF04082.18 EJS42438.1 - 3.5e-24 85.3 13.0 3.5e-24 85.3 13.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS42438.1 - 1.3e-08 34.9 15.2 1.3e-08 34.9 15.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.24 EJS42439.1 - 2.1e-77 261.3 0.0 2.6e-77 261.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJS42439.1 - 2.5e-13 50.0 0.3 5.2e-13 49.0 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJS42439.1 - 4e-06 26.2 1.8 5.5e-06 25.7 1.8 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EJS42439.1 - 4.2e-06 26.2 0.0 0.00052 19.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJS42439.1 - 2.8e-05 23.5 1.6 0.0013 18.1 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EJS42439.1 - 0.0001 21.7 0.3 0.00016 21.1 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJS42439.1 - 0.00096 18.8 0.6 0.0015 18.2 0.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EJS42439.1 - 0.0013 18.0 0.2 0.0023 17.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EJS42439.1 - 0.0019 17.0 1.8 0.021 13.6 0.5 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EJS42439.1 - 0.0024 17.0 1.9 0.0098 15.0 0.8 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EJS42439.1 - 0.0047 16.0 0.0 0.46 9.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EJS42439.1 - 0.0062 15.9 0.1 0.0095 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EJS42439.1 - 0.02 14.2 0.3 0.038 13.3 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EJS42439.1 - 0.02 15.5 1.5 0.047 14.2 0.4 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJS42439.1 - 0.073 13.1 0.6 14 5.7 0.2 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EJS42439.1 - 0.08 13.0 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pdase_C33_assoc PF14756.6 EJS42439.1 - 0.15 12.0 0.1 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Peptidase_C33-associated domain Copper-fist PF00649.18 EJS42440.1 - 8.5e-20 70.0 4.3 2.2e-19 68.6 4.3 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain UQ_con PF00179.26 EJS42441.1 - 4.3e-49 165.8 0.0 4.8e-49 165.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EJS42441.1 - 0.059 13.7 2.1 0.2 12.0 1.2 2.2 2 1 0 2 2 2 0 RWD domain MnmE_helical PF12631.7 EJS42442.1 - 5.6e-43 147.5 1.9 7.4e-43 147.1 1.9 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EJS42442.1 - 8.1e-34 116.4 0.0 5.5e-33 113.7 0.0 2.2 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EJS42442.1 - 2.5e-24 85.6 1.1 3.9e-24 84.9 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJS42442.1 - 1.4e-15 57.2 0.4 2.8e-15 56.2 0.4 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EJS42442.1 - 2e-09 37.6 0.3 0.0006 19.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Ras PF00071.22 EJS42442.1 - 3.4e-08 33.2 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 EJS42442.1 - 2.5e-07 30.5 0.4 4.4e-06 26.4 0.2 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 EJS42442.1 - 9.5e-06 25.2 0.4 5.6e-05 22.7 0.4 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EJS42442.1 - 6.9e-05 23.1 0.0 0.00058 20.1 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EJS42442.1 - 0.00015 21.5 0.0 0.0066 16.2 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 EJS42442.1 - 0.00047 20.1 0.1 0.0018 18.3 0.1 2.0 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 EJS42442.1 - 0.01 15.9 0.1 0.044 13.8 0.1 2.1 1 0 0 1 1 1 0 Dynamin family NOG1 PF06858.14 EJS42442.1 - 0.018 14.8 0.3 0.063 13.1 0.3 2.0 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) AIG1 PF04548.16 EJS42442.1 - 0.036 13.4 1.3 0.3 10.4 0.2 2.4 2 0 0 2 2 2 0 AIG1 family AAA_28 PF13521.6 EJS42442.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pex2_Pex12 PF04757.14 EJS42444.1 - 7e-41 140.3 14.8 9e-41 139.9 14.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EJS42444.1 - 8.3e-06 25.6 2.8 1.4e-05 24.8 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJS42444.1 - 0.0019 18.0 3.9 0.0032 17.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EJS42444.1 - 0.02 15.0 7.5 0.037 14.2 7.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TMEM234 PF10639.9 EJS42444.1 - 0.068 13.2 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Putative transmembrane family 234 zf-C3HC4 PF00097.25 EJS42444.1 - 0.27 11.1 5.0 0.5 10.3 5.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJS42444.1 - 0.83 9.7 6.2 1.9 8.6 6.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger TAP42 PF04177.12 EJS42445.1 - 1.7e-81 273.8 13.8 2e-81 273.6 13.8 1.0 1 0 0 1 1 1 1 TAP42-like family Eisosome1 PF12757.7 EJS42446.1 - 7.6e-32 110.2 1.4 7.6e-32 110.2 1.4 5.1 4 1 0 4 4 4 1 Eisosome protein 1 FCH PF00611.23 EJS42447.1 - 8.2e-16 58.1 0.0 1.9e-14 53.7 0.0 2.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EJS42447.1 - 0.00057 19.4 0.0 0.0016 18.0 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EJS42447.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Cytochrom_B562 PF07361.11 EJS42447.1 - 4.2 8.1 19.6 3.5 8.3 2.9 4.1 4 1 0 4 4 4 0 Cytochrome b562 Peptidase_S24 PF00717.23 EJS42448.1 - 3e-08 33.5 0.0 1e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EJS42448.1 - 0.00071 19.4 0.0 0.0033 17.2 0.0 1.9 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Rhodanese PF00581.20 EJS42449.1 - 1.8e-11 44.5 0.0 3.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain 3H PF02829.14 EJS42449.1 - 0.17 12.2 0.6 0.71 10.2 0.0 2.1 2 0 0 2 2 2 0 3H domain zf-C2H2 PF00096.26 EJS42450.1 - 1.3e-11 44.3 18.2 6.6e-06 26.3 2.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJS42450.1 - 4.8e-07 29.9 20.4 1.6e-05 25.1 3.5 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EJS42450.1 - 3.3e-06 27.2 16.2 0.0022 18.2 5.6 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EJS42450.1 - 6.8e-06 26.5 24.7 0.00048 20.7 2.0 3.0 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 EJS42450.1 - 0.0018 18.6 11.3 0.027 14.9 2.8 3.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 EJS42450.1 - 0.011 15.5 2.7 1.3 8.9 0.4 2.6 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.7 EJS42450.1 - 0.038 14.4 20.0 0.084 13.3 2.2 3.2 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 EJS42450.1 - 0.061 13.6 8.5 0.15 12.4 8.5 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 EJS42450.1 - 0.14 12.1 16.2 0.21 11.6 4.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.12 EJS42450.1 - 3.3 6.1 12.9 2.6 6.5 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-H2C2_5 PF13909.6 EJS42450.1 - 3.6 7.4 14.2 2.4 8.0 1.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain HMA PF00403.26 EJS42451.1 - 2.9e-13 50.0 0.1 1.5e-12 47.8 0.0 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain Sod_Cu PF00080.20 EJS42451.1 - 2.1e-08 34.4 0.0 4.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PC4 PF02229.16 EJS42452.1 - 5.5e-22 77.1 0.1 9.7e-22 76.4 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Transglut_i_TM PF14400.6 EJS42452.1 - 4.7 7.2 11.1 15 5.7 11.1 2.0 1 1 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices DUF1773 PF08593.10 EJS42452.1 - 8.3 7.5 8.3 5 8.2 3.6 2.7 2 1 0 2 2 2 0 Domain of unknown function SRF-TF PF00319.18 EJS42453.1 - 4.3e-21 74.1 0.2 6.4e-21 73.6 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) RR_TM4-6 PF06459.12 EJS42453.1 - 0.24 11.2 23.3 0.44 10.3 23.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 EJS42453.1 - 0.31 10.7 14.9 0.054 13.1 1.4 2.4 2 0 0 2 2 2 0 FAM176 family CAC1F_C PF16885.5 EJS42453.1 - 0.51 9.9 22.6 0.72 9.5 22.6 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term SUIM_assoc PF16619.5 EJS42453.1 - 0.55 10.3 0.0 0.55 10.3 0.0 5.7 3 2 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 GREB1 PF15782.5 EJS42453.1 - 1 6.4 26.8 1.3 6.1 26.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FYDLN_acid PF09538.10 EJS42453.1 - 2.4 8.9 15.6 1.8 9.3 3.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2981 PF11200.8 EJS42453.1 - 2.8 7.6 10.6 3.6 7.2 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) GOLD_2 PF13897.6 EJS42453.1 - 6.3 7.3 11.0 0.94 10.0 2.5 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking PWWP PF00855.17 EJS42454.1 - 2.2e-19 69.6 4.4 2.4e-19 69.5 0.5 3.0 2 1 0 2 2 2 1 PWWP domain Swi3 PF07962.12 EJS42455.1 - 1.3e-26 92.4 0.7 2e-26 91.8 0.1 1.7 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 BOP1NT PF08145.12 EJS42456.1 - 1.1e-103 346.7 6.9 2e-103 345.8 6.9 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EJS42456.1 - 5e-24 84.1 7.8 2.9e-09 37.4 0.2 6.8 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS42456.1 - 1.7e-08 34.6 0.5 0.0012 19.1 0.0 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF-3c_N PF05470.12 EJS42456.1 - 0.0036 15.7 1.0 1e+02 1.0 0.0 2.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NESP55 PF06390.12 EJS42456.1 - 4 7.0 15.1 7.7 6.0 15.1 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) TPT PF03151.16 EJS42457.1 - 7.9e-17 61.5 15.1 1.4e-09 37.7 6.4 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family PUNUT PF16913.5 EJS42457.1 - 6.4e-10 38.8 4.0 6.4e-10 38.8 4.0 2.1 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport EamA PF00892.20 EJS42457.1 - 4.2e-09 36.7 28.2 4.4e-05 23.7 8.1 3.6 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 EJS42457.1 - 6.6e-09 35.4 1.3 6.6e-09 35.4 1.3 2.2 2 0 0 2 2 2 1 UAA transporter family SLC35F PF06027.12 EJS42457.1 - 4.6e-06 26.4 2.2 4.6e-06 26.4 2.2 1.9 2 0 0 2 2 2 1 Solute carrier family 35 TMEM234 PF10639.9 EJS42457.1 - 0.0046 17.0 9.0 0.29 11.2 1.0 2.8 3 0 0 3 3 3 2 Putative transmembrane family 234 A_deaminase PF00962.22 EJS42458.1 - 1.2e-133 445.5 0.0 1.8e-133 445.0 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase ubiquitin PF00240.23 EJS42459.1 - 0.00012 21.8 0.1 0.00073 19.2 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EJS42459.1 - 0.00047 19.9 0.0 0.0047 16.7 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EJS42459.1 - 0.0019 18.3 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EJS42459.1 - 0.0047 17.5 0.0 0.015 15.9 0.0 1.9 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain AhpC-TSA PF00578.21 EJS42460.1 - 1.8e-35 121.6 0.0 1.8e-34 118.3 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EJS42460.1 - 2.5e-18 66.2 0.0 5.4e-18 65.1 0.0 1.5 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 EJS42460.1 - 5.3e-09 35.8 0.3 1e-08 34.9 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EJS42460.1 - 0.0077 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC Homeodomain PF00046.29 EJS42461.1 - 3.1e-17 62.1 2.6 7.2e-17 61.0 2.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EJS42461.1 - 0.0002 21.2 0.5 0.0017 18.2 0.1 2.4 2 0 0 2 2 2 1 Homeobox KN domain Pribosyltran PF00156.27 EJS42462.1 - 1.1e-14 54.2 0.0 1.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EJS42462.1 - 0.043 13.2 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase OST3_OST6 PF04756.13 EJS42464.1 - 1.2e-70 238.2 5.9 1.4e-70 237.9 5.9 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EJS42464.1 - 0.035 14.1 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Virul_fac_BrkB PF03631.15 EJS42464.1 - 0.3 10.6 7.0 0.16 11.6 4.1 1.9 1 1 1 2 2 2 0 Virulence factor BrkB DUF3522 PF12036.8 EJS42464.1 - 6.5 7.0 10.1 0.47 10.7 1.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3522) EamA PF00892.20 EJS42465.1 - 8.7e-11 42.1 30.4 3.7e-06 27.1 3.0 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 EJS42465.1 - 0.0072 16.1 3.4 0.0072 16.1 3.4 4.7 5 0 0 5 5 5 1 Protein of unknown function (DUF3955) Macoilin PF09726.9 EJS42466.1 - 0.38 9.3 5.8 0.42 9.1 5.8 1.0 1 0 0 1 1 1 0 Macoilin family SUR7 PF06687.12 EJS42467.1 - 3e-40 138.1 9.9 4.2e-40 137.6 9.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EJS42467.1 - 2.7e-06 27.4 3.9 5.7e-06 26.4 3.9 1.5 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF805 PF05656.14 EJS42467.1 - 9.6 6.7 10.9 1.2 9.6 5.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) GFO_IDH_MocA PF01408.22 EJS42468.1 - 5e-08 33.8 0.0 7.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EJS42468.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Suc_Fer-like PF06999.12 EJS42469.1 - 4.1e-29 101.8 0.0 5e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like WSN PF02206.18 EJS42469.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function Gsf2 PF11055.8 EJS42470.1 - 1.2e-175 583.7 0.1 1.5e-175 583.4 0.1 1.1 1 0 0 1 1 1 1 Glucose signalling factor 2 Kin17_mid PF10357.9 EJS42471.1 - 0.00012 22.0 2.5 0.00036 20.4 0.2 2.9 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein Mad3_BUB1_I PF08311.12 EJS42471.1 - 2.7 8.0 10.9 0.29 11.1 0.1 4.3 4 2 1 5 5 5 0 Mad3/BUB1 homology region 1 RNA_pol_I_TF PF04090.12 EJS42472.1 - 6.9e-76 254.2 2.4 1.6e-75 253.0 2.4 1.7 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor Fzo_mitofusin PF04799.13 EJS42472.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 fzo-like conserved region Carn_acyltransf PF00755.20 EJS42473.1 - 7.5e-178 592.8 0.1 8.7e-178 592.6 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-HIT PF04438.16 EJS42474.1 - 0.016 15.0 9.9 0.029 14.3 9.9 1.4 1 0 0 1 1 1 0 HIT zinc finger NRDD PF13597.6 EJS42474.1 - 0.16 10.7 2.0 0.24 10.1 2.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase ADH_N_2 PF16884.5 EJS42475.1 - 7.3e-23 80.5 0.0 1.4e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EJS42475.1 - 1.8e-16 60.3 0.9 2.8e-16 59.7 0.9 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJS42475.1 - 0.00023 22.2 0.0 0.00052 21.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LAB_N PF07578.11 EJS42475.1 - 0.032 14.3 0.3 0.081 13.0 0.3 1.6 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain DUF2855 PF11017.8 EJS42475.1 - 0.047 13.4 0.1 0.24 11.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) ERO1 PF04137.15 EJS42476.1 - 6.8e-115 384.0 1.4 6.8e-115 384.0 1.4 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF2718 PF10918.8 EJS42476.1 - 0.016 15.7 2.4 0.14 12.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) COX14 PF14880.6 EJS42477.1 - 1.8e-24 85.3 2.5 2.2e-24 85.0 2.5 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Ish1 PF10281.9 EJS42478.1 - 5.5e-50 167.4 53.2 1.6e-12 47.5 0.3 7.6 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EJS42478.1 - 2.7e-05 23.8 0.1 7.6 6.4 0.0 5.9 7 0 0 7 7 7 1 SAP domain DUF3892 PF13031.6 EJS42478.1 - 5.3e-05 23.8 10.5 0.93 10.2 0.0 5.7 4 2 0 4 4 4 2 Protein of unknown function (DUF3892) ICEA PF05315.11 EJS42478.1 - 0.0017 17.9 0.8 0.0017 17.9 0.8 2.7 4 0 0 4 4 4 1 ICEA Protein YtxH PF12732.7 EJS42478.1 - 0.0076 16.8 18.2 2.7 8.6 0.0 5.7 4 2 1 5 5 5 1 YtxH-like protein BRCT PF00533.26 EJS42478.1 - 0.077 13.4 4.1 10 6.5 0.2 3.7 3 2 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Slx4 PF09494.10 EJS42478.1 - 0.12 12.4 2.3 1.2e+02 2.7 0.0 5.0 6 0 0 6 6 6 0 Slx4 endonuclease DUF4286 PF14114.6 EJS42478.1 - 0.19 12.2 9.5 6.6 7.3 0.3 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4286) DUF4230 PF14014.6 EJS42478.1 - 0.23 11.7 12.4 15 5.9 0.5 5.1 3 2 2 5 5 5 0 Protein of unknown function (DUF4230) SAM_2 PF07647.17 EJS42478.1 - 0.32 11.1 14.8 22 5.2 0.0 6.1 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) DUF2795 PF11387.8 EJS42478.1 - 0.52 10.6 2.0 1.4e+02 2.7 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2795) SAM_1 PF00536.30 EJS42478.1 - 0.66 10.5 9.9 92 3.6 0.2 5.4 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) GP52 PF17468.2 EJS42478.1 - 3.1 8.0 7.5 9.9 6.4 0.0 4.0 4 0 0 4 4 4 0 Phage gene product 52 NYD-SP28 PF14772.6 EJS42478.1 - 7.5 6.7 11.2 24 5.1 0.2 3.6 2 1 1 3 3 3 0 Sperm tail FAD_binding_6 PF00970.24 EJS42480.1 - 8.1e-32 109.5 0.0 3.4e-31 107.5 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EJS42480.1 - 5.4e-26 91.4 0.0 8.1e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EJS42480.1 - 0.00035 20.7 0.0 0.0023 18.1 0.0 2.0 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Sugar_tr PF00083.24 EJS42481.1 - 1.7e-51 175.5 10.8 2.2e-51 175.1 10.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS42481.1 - 1.4e-27 96.6 13.7 2e-22 79.6 8.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAM178 PF14816.6 EJS42481.1 - 0.083 11.9 0.2 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function, FAM178 Gtr1_RagA PF04670.12 EJS42482.1 - 5.1e-94 314.0 1.2 6.6e-94 313.6 1.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EJS42482.1 - 2e-09 37.2 0.3 8.4e-09 35.2 0.1 1.9 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EJS42482.1 - 2.1e-08 34.4 0.0 4.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS42482.1 - 1.1e-07 31.5 0.1 2.2e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EJS42482.1 - 2.1e-07 31.0 0.0 4.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EJS42482.1 - 0.0088 16.6 0.1 0.021 15.4 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AIG1 PF04548.16 EJS42482.1 - 0.036 13.4 0.6 0.37 10.1 0.1 2.4 1 1 0 2 2 2 0 AIG1 family DUF815 PF05673.13 EJS42482.1 - 0.041 13.0 0.0 0.1 11.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 EJS42482.1 - 0.048 13.3 1.1 0.17 11.6 0.3 2.2 2 1 0 2 2 2 0 Guanylate kinase AAA_29 PF13555.6 EJS42482.1 - 0.05 13.3 0.3 0.1 12.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJS42482.1 - 0.058 13.3 0.6 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase Pyr_redox_2 PF07992.14 EJS42483.1 - 1.8e-49 168.6 0.0 2.2e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJS42483.1 - 3e-13 50.1 0.1 5.6e-11 42.8 0.3 3.2 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJS42483.1 - 1.8e-05 24.2 1.0 0.78 8.9 0.1 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJS42483.1 - 0.1 11.2 0.2 12 4.4 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein Anp1 PF03452.14 EJS42484.1 - 1.2e-120 401.9 0.0 1.7e-120 401.3 0.0 1.3 1 0 0 1 1 1 1 Anp1 Plasmodium_Vir PF05795.11 EJS42484.1 - 0.022 14.2 7.1 0.013 14.9 2.9 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein TAF8_C PF10406.9 EJS42485.1 - 7.8e-18 64.8 0.1 7.8e-18 64.8 0.1 2.8 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term MEKHLA PF08670.11 EJS42485.1 - 0.62 9.9 2.6 2.8 7.8 0.1 2.3 1 1 1 2 2 2 0 MEKHLA domain CTK3_C PF12350.8 EJS42487.1 - 4.8e-17 61.9 0.5 9.9e-17 60.9 0.5 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 EJS42487.1 - 0.0066 16.4 1.7 0.41 10.6 0.1 2.7 2 1 0 2 2 2 2 CTD kinase subunit gamma CTK3 V-set_2 PF15910.5 EJS42487.1 - 0.0072 16.4 1.1 0.017 15.2 0.3 2.0 1 1 1 2 2 2 1 ICOS V-set domain Bul1_N PF04425.12 EJS42488.1 - 5.7e-171 569.2 4.7 5.7e-171 569.2 4.7 2.1 2 1 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.12 EJS42488.1 - 6.6e-112 373.4 11.1 6.6e-112 373.4 11.1 2.3 2 0 0 2 2 2 1 Bul1 C terminus SurA_N_2 PF13623.6 EJS42488.1 - 0.11 12.3 0.3 0.26 11.2 0.3 1.5 1 0 0 1 1 1 0 SurA N-terminal domain Ubie_methyltran PF01209.18 EJS42489.1 - 5.6e-105 349.8 0.1 6.5e-105 349.6 0.1 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EJS42489.1 - 3.8e-11 43.5 0.0 7.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJS42489.1 - 9.3e-09 35.2 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJS42489.1 - 1.6e-08 35.1 0.0 3.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJS42489.1 - 3e-07 31.1 0.0 5.1e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJS42489.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EJS42489.1 - 0.023 14.5 0.0 0.27 11.1 0.0 2.2 1 1 1 2 2 2 0 Hypothetical methyltransferase ADH_zinc_N PF00107.26 EJS42489.1 - 0.17 11.8 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1892 PF08987.10 EJS42490.1 - 4.7e-48 161.9 6.6 5.2e-48 161.8 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) zf-C3HC PF07967.13 EJS42491.1 - 3.1e-11 43.4 5.0 1.1e-09 38.4 2.3 2.5 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EJS42491.1 - 0.00021 21.4 3.5 0.009 16.1 0.7 2.6 2 0 0 2 2 2 2 Rsm1-like Pribosyltran PF00156.27 EJS42492.1 - 3.5e-16 59.1 0.2 5.2e-16 58.6 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SRP19 PF01922.17 EJS42493.1 - 2.7e-29 101.9 0.0 4.8e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Nup188 PF10487.9 EJS42494.1 - 2.8e-242 806.6 61.5 2.8e-242 806.6 61.5 2.6 2 1 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 EJS42494.1 - 4e-20 72.0 3.9 1.5e-19 70.1 3.9 2.0 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain CUE PF02845.16 EJS42495.1 - 7.3e-08 32.0 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 CUE domain DUF3391 PF11871.8 EJS42495.1 - 0.011 16.3 0.7 0.012 16.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) COX2_TM PF02790.15 EJS42495.1 - 0.047 13.8 0.1 4.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Shisa PF13908.6 EJS42495.1 - 0.64 10.2 4.1 0.78 10.0 4.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Glyco_transf_20 PF00982.21 EJS42496.1 - 5e-172 572.8 0.4 8e-172 572.2 0.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EJS42496.1 - 1.8e-51 174.5 0.1 4.3e-51 173.3 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_trans_1_4 PF13692.6 EJS42496.1 - 0.02 15.3 0.0 0.049 14.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 IL34 PF15036.6 EJS42496.1 - 0.062 13.3 0.6 0.74 9.8 0.0 2.7 3 0 0 3 3 3 0 Interleukin 34 Fungal_trans_2 PF11951.8 EJS42497.1 - 5.3e-111 371.1 1.5 7.4e-111 370.7 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS42497.1 - 9.3e-13 48.1 7.4 2.6e-12 46.7 7.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CNOT11 PF10155.9 EJS42497.1 - 0.043 14.0 0.5 3.8 7.7 0.0 2.3 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 TFIID-18kDa PF02269.16 EJS42498.1 - 3.1e-36 123.3 0.0 4.6e-36 122.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.15 EJS42498.1 - 0.025 14.6 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EJS42498.1 - 0.038 14.4 0.0 0.038 14.4 0.0 2.4 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EJS42498.1 - 0.046 13.9 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) VPS9 PF02204.18 EJS42499.1 - 2.2e-30 104.9 0.1 6.4e-30 103.4 0.1 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EJS42499.1 - 5.5e-12 45.8 0.2 5.5e-12 45.8 0.2 2.8 3 1 1 4 4 4 1 Domain of unknown function (DUF5601) CUE PF02845.16 EJS42499.1 - 1.9e-11 43.4 0.0 3.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain Rad10 PF03834.14 EJS42500.1 - 1.2e-36 125.1 1.5 1.2e-36 125.1 1.5 1.5 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) TORC_N PF12884.7 EJS42500.1 - 0.084 13.7 0.7 0.18 12.6 0.4 1.7 1 1 0 1 1 1 0 Transducer of regulated CREB activity, N terminus Utp14 PF04615.13 EJS42501.1 - 4.3e-203 677.0 86.6 4.3e-203 677.0 86.6 2.0 1 1 1 2 2 2 1 Utp14 protein Proteasome PF00227.26 EJS42502.1 - 2.3e-58 196.8 0.0 3e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJS42502.1 - 1.4e-09 37.5 0.2 4.7e-09 35.8 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD_binding_6 PF00970.24 EJS42503.1 - 2.4e-31 108.0 0.0 3.8e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EJS42503.1 - 8.4e-26 90.8 0.0 1.2e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EJS42503.1 - 1.4e-05 25.2 0.0 0.0012 19.0 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Cys_Met_Meta_PP PF01053.20 EJS42505.1 - 1.1e-20 73.5 0.0 2.5e-20 72.4 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ATP-synt_J PF04911.12 EJS42506.1 - 2.9e-29 100.4 1.1 3.2e-29 100.3 1.1 1.0 1 0 0 1 1 1 1 ATP synthase j chain zf-C2H2 PF00096.26 EJS42507.1 - 5.8e-06 26.5 15.6 0.00036 20.8 3.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJS42507.1 - 0.00027 21.2 9.0 0.00062 20.1 4.4 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJS42507.1 - 0.0031 18.2 15.0 0.023 15.5 3.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger Dus PF01207.17 EJS42508.1 - 1.1e-88 297.4 0.0 1.4e-88 297.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Cupin_5 PF06172.11 EJS42509.1 - 1.3e-44 151.7 0.0 1.6e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Pro_isomerase PF00160.21 EJS42510.1 - 2.9e-48 164.1 0.0 3.6e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sybindin PF04099.12 EJS42511.1 - 9.8e-20 70.9 0.3 1.2e-19 70.6 0.3 1.1 1 0 0 1 1 1 1 Sybindin-like family LptD PF04453.14 EJS42511.1 - 0.0027 17.0 0.1 0.0033 16.7 0.1 1.2 1 0 0 1 1 1 1 LPS transport system D Sedlin_N PF04628.13 EJS42511.1 - 0.0087 16.2 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Zn_clus PF00172.18 EJS42512.1 - 0.015 15.4 15.0 0.033 14.3 15.0 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HMG-CoA_red PF00368.18 EJS42513.1 - 4.1e-144 480.1 0.8 7.4e-144 479.3 0.8 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 EJS42513.1 - 1.3e-44 151.7 1.7 1.3e-44 151.7 1.7 2.1 2 0 0 2 2 2 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 EJS42513.1 - 2e-07 31.0 5.8 2e-07 31.0 5.8 1.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation FKBP_C PF00254.28 EJS42514.1 - 1e-29 102.7 0.0 3.2e-28 97.9 0.0 2.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EJS42514.1 - 4.9e-23 81.7 1.7 4.9e-23 81.7 1.7 2.7 2 1 0 2 2 2 1 Nucleoplasmin-like domain Presenilin PF01080.17 EJS42514.1 - 0.69 8.6 18.7 0.38 9.5 8.1 2.1 2 0 0 2 2 2 0 Presenilin FAM60A PF15396.6 EJS42514.1 - 2.8 7.9 17.7 3.3 7.7 2.3 2.2 2 0 0 2 2 2 0 Protein Family FAM60A TFIIF_alpha PF05793.12 EJS42514.1 - 3.5 6.1 68.9 3.3 6.2 23.9 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CCSAP PF15748.5 EJS42514.1 - 5.1 7.2 26.7 2.8 8.1 14.6 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Neur_chan_memb PF02932.16 EJS42514.1 - 6.1 6.8 9.1 9.2 6.2 4.4 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region C2 PF00168.30 EJS42515.1 - 3.8e-55 184.5 2.4 3.1e-18 66.0 0.1 5.7 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EJS42515.1 - 0.0072 15.8 0.3 0.42 10.1 0.0 2.3 2 0 0 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain OmpH PF03938.14 EJS42515.1 - 3.3 8.1 10.0 8.2 6.8 10.0 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Dor1 PF04124.12 EJS42516.1 - 8.1e-72 241.7 6.6 4.5e-71 239.3 5.5 2.0 2 0 0 2 2 2 1 Dor1-like family Hid1 PF12722.7 EJS42516.1 - 1.7e-05 23.3 6.1 2.9e-05 22.4 6.1 1.4 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein TPR_7 PF13176.6 EJS42516.1 - 0.057 13.5 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Neur_chan_memb PF02932.16 EJS42516.1 - 3.1 7.8 8.9 6.4 6.8 8.9 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dak1 PF02733.17 EJS42517.1 - 5.7e-109 363.8 0.3 8.1e-109 363.3 0.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EJS42517.1 - 3.2e-46 157.4 2.7 3.3e-46 157.3 1.1 1.8 2 0 0 2 2 2 1 DAK2 domain SSrecog PF03531.14 EJS42518.1 - 4.9e-30 103.2 0.9 4.6e-28 96.9 0.0 3.5 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EJS42518.1 - 2.8e-28 98.1 0.1 4.2e-25 88.0 0.0 3.2 3 0 0 3 3 3 1 Histone chaperone Rttp106-like POB3_N PF17292.2 EJS42518.1 - 5.1e-28 97.3 0.3 7.4e-26 90.4 0.1 2.7 2 0 0 2 2 2 1 POB3-like N-terminal PH domain IBR PF01485.21 EJS42519.1 - 1.1e-13 51.1 28.0 7.2e-10 38.9 1.9 4.8 4 2 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EJS42519.1 - 0.0056 17.0 9.4 0.0056 17.0 9.4 5.2 4 2 1 5 5 5 2 Ring finger domain Fig1 PF12351.8 EJS42520.1 - 1.8 8.4 6.9 6.6 6.6 0.0 2.9 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 AAA_lid_10 PF17872.1 EJS42521.1 - 1.7e-43 146.8 0.0 8e-43 144.6 0.0 2.3 1 0 0 1 1 1 1 AAA lid domain BAH PF01426.18 EJS42521.1 - 1.5e-21 76.5 0.1 4.7e-21 74.9 0.1 1.9 1 0 0 1 1 1 1 BAH domain AAA PF00004.29 EJS42521.1 - 8.2e-20 71.6 0.0 2.9e-19 69.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EJS42521.1 - 2.6e-08 34.2 0.0 2.4e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJS42521.1 - 5.4e-07 30.1 0.3 6.7e-05 23.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 EJS42521.1 - 0.0019 18.2 0.5 0.0019 18.2 0.5 4.1 4 1 0 4 4 4 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EJS42521.1 - 0.0027 18.0 0.4 0.0027 18.0 0.4 2.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EJS42521.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EJS42521.1 - 0.068 13.7 0.0 0.068 13.7 0.0 3.2 3 0 0 3 3 2 0 AAA domain Nop14 PF04147.12 EJS42521.1 - 0.11 10.7 30.3 0.05 11.8 22.8 2.2 2 0 0 2 2 2 0 Nop14-like family UCR_TM PF02921.14 EJS42521.1 - 0.13 12.8 1.8 4.6 7.8 0.1 3.0 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region CDC45 PF02724.14 EJS42521.1 - 0.71 8.1 26.1 0.017 13.4 15.7 2.3 2 0 0 2 2 2 0 CDC45-like protein AAA_11 PF13086.6 EJS42521.1 - 0.82 9.4 0.0 0.82 9.4 0.0 3.3 2 1 0 2 2 1 0 AAA domain RNA_pol_3_Rpc31 PF11705.8 EJS42521.1 - 0.9 9.8 34.3 0.38 11.0 18.9 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 EJS42521.1 - 2.7 7.2 35.8 0.63 9.3 27.9 2.3 2 0 0 2 2 2 0 BUD22 NOA36 PF06524.12 EJS42521.1 - 5 6.4 31.4 3.3 6.9 16.4 2.2 2 0 0 2 2 2 0 NOA36 protein TFIIF_alpha PF05793.12 EJS42521.1 - 6.7 5.2 38.1 0.095 11.3 27.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ras PF00071.22 EJS42522.1 - 5.4e-30 104.1 0.1 6.6e-30 103.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS42522.1 - 1.5e-20 73.6 0.0 2.6e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EJS42522.1 - 2.9e-06 26.8 0.1 3.8e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EJS42522.1 - 7.1e-05 22.3 0.1 9e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DLIC PF05783.11 EJS42522.1 - 0.001 18.0 0.2 0.11 11.3 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) AAA_7 PF12775.7 EJS42522.1 - 0.0023 17.4 0.7 0.0064 16.0 0.1 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EJS42522.1 - 0.0087 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_S3Ae PF01015.18 EJS42523.1 - 2.4e-86 288.5 5.0 2.8e-86 288.2 5.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 EJS42523.1 - 0.038 13.6 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region HhH-GPD PF00730.25 EJS42524.1 - 1.4e-23 83.4 0.0 3.5e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.12 EJS42524.1 - 6.2e-22 77.9 0.2 1.4e-21 76.9 0.2 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain Maf PF02545.14 EJS42524.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Maf-like protein cNMP_binding PF00027.29 EJS42525.1 - 1e-28 99.2 0.6 1.3e-14 54.0 0.0 5.7 5 1 0 5 5 5 2 Cyclic nucleotide-binding domain Patatin PF01734.22 EJS42525.1 - 4.3e-19 69.5 2.5 1.5e-12 48.1 0.6 3.7 4 0 0 4 4 4 2 Patatin-like phospholipase Big_1 PF02369.16 EJS42525.1 - 0.1 12.6 0.6 0.32 11.0 0.6 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) TspO_MBR PF03073.15 EJS42525.1 - 0.12 12.4 9.4 0.31 11.1 9.4 1.6 1 0 0 1 1 1 0 TspO/MBR family CCDC32 PF14989.6 EJS42525.1 - 0.29 11.1 4.7 0.073 13.1 0.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing 32 SPC25 PF06703.11 EJS42527.1 - 8.9e-36 123.1 1.8 1e-35 123.0 1.8 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) YesK PF14150.6 EJS42527.1 - 0.1 12.8 0.4 0.18 12.0 0.4 1.3 1 0 0 1 1 1 0 YesK-like protein Pkinase PF00069.25 EJS42528.1 - 6.5e-57 192.9 0.0 3.9e-56 190.4 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42528.1 - 1.3e-21 77.0 0.0 2.5e-20 72.9 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS42528.1 - 0.00016 21.1 0.0 0.34 10.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EJS42528.1 - 0.00019 20.9 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 EJS42529.1 - 8.1e-43 146.2 0.4 4.1e-21 75.9 0.0 4.8 4 2 0 4 4 2 2 ABC transporter 4HB PF17947.1 EJS42529.1 - 9.5e-29 99.3 0.9 2.4e-28 98.0 0.1 2.2 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 EJS42529.1 - 1.7e-16 60.9 1.5 0.0047 16.8 0.0 4.8 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJS42529.1 - 5.1e-16 58.8 0.1 3.1e-06 26.8 0.0 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EJS42529.1 - 1.2e-10 42.3 4.4 0.0005 20.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EJS42529.1 - 5.1e-08 33.0 0.0 0.00034 20.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 EJS42529.1 - 5.2e-08 33.3 0.0 0.012 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EJS42529.1 - 5.6e-08 33.2 0.0 0.0051 17.1 0.0 4.0 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.6 EJS42529.1 - 7.8e-08 31.9 0.0 0.013 15.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EJS42529.1 - 4e-07 30.1 0.0 0.0029 17.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 EJS42529.1 - 1.7e-06 28.5 0.0 0.13 12.6 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EJS42529.1 - 1.9e-06 28.2 0.0 0.13 12.7 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 EJS42529.1 - 7.4e-06 26.0 0.0 0.078 12.9 0.0 3.1 3 0 0 3 3 3 2 Rad17 P-loop domain Dynamin_N PF00350.23 EJS42529.1 - 7.5e-06 26.1 0.0 0.00012 22.1 0.0 2.6 2 0 0 2 2 2 1 Dynamin family MeaB PF03308.16 EJS42529.1 - 1.5e-05 24.1 0.0 0.12 11.3 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EJS42529.1 - 1.5e-05 25.5 0.1 0.18 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain ParcG PF10274.9 EJS42529.1 - 2.9e-05 24.3 0.6 0.52 10.4 0.0 3.2 2 1 1 3 3 3 1 Parkin co-regulated protein AAA_16 PF13191.6 EJS42529.1 - 0.00014 22.3 0.0 0.48 10.8 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 EJS42529.1 - 0.00017 21.8 0.0 0.65 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EJS42529.1 - 0.00029 20.8 0.0 0.089 12.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 EJS42529.1 - 0.00032 20.7 0.1 0.24 11.3 0.0 3.1 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 EJS42529.1 - 0.00032 20.9 2.0 0.4 10.7 0.0 4.2 5 0 0 5 5 3 1 Helicase HerA, central domain AAA_27 PF13514.6 EJS42529.1 - 0.00044 19.9 0.0 0.56 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EJS42529.1 - 0.00058 19.9 0.0 1.3 9.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 EJS42529.1 - 0.00084 19.1 0.0 0.28 10.9 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation HEAT_EZ PF13513.6 EJS42529.1 - 0.0012 19.3 0.4 0.38 11.3 0.1 3.7 4 0 0 4 4 2 1 HEAT-like repeat AAA_15 PF13175.6 EJS42529.1 - 0.0015 18.3 9.1 0.22 11.2 0.0 3.9 5 0 0 5 5 3 2 AAA ATPase domain UME PF08064.13 EJS42529.1 - 0.0016 18.3 1.2 0.11 12.5 0.8 3.0 2 1 1 3 3 3 1 UME (NUC010) domain SbcCD_C PF13558.6 EJS42529.1 - 0.0021 18.3 0.0 0.81 10.0 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EJS42529.1 - 0.0023 17.7 0.1 1.7 8.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain HEAT_2 PF13646.6 EJS42529.1 - 0.0077 16.6 0.1 0.094 13.1 0.0 2.7 2 1 1 3 3 2 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EJS42529.1 - 0.0082 16.7 0.4 9.1 7.0 0.0 3.9 2 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region AAA_30 PF13604.6 EJS42529.1 - 0.0087 15.8 0.1 11 5.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 EJS42529.1 - 0.016 15.2 0.1 8.8 6.2 0.0 3.0 2 0 0 2 2 2 0 NTPase Adeno_IVa2 PF02456.15 EJS42529.1 - 0.016 14.0 0.0 2.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein MutS_V PF00488.21 EJS42529.1 - 0.023 14.7 0.1 11 6.0 0.1 2.6 2 0 0 2 2 2 0 MutS domain V G-alpha PF00503.20 EJS42529.1 - 0.025 13.7 0.0 4.8 6.2 0.0 2.6 2 0 0 2 2 2 0 G-protein alpha subunit Tricho_coat PF05892.11 EJS42529.1 - 0.028 14.2 0.0 0.097 12.4 0.0 1.8 2 0 0 2 2 1 0 Trichovirus coat protein Mg_chelatase PF01078.21 EJS42529.1 - 0.03 13.7 0.2 1.1 8.6 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI CLP1_P PF16575.5 EJS42529.1 - 0.034 14.0 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop cobW PF02492.19 EJS42529.1 - 0.036 13.7 0.0 14 5.3 0.0 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EJS42529.1 - 0.039 14.2 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RE_HindVP PF09519.10 EJS42529.1 - 0.046 12.7 0.6 0.077 12.0 0.6 1.3 1 0 0 1 1 1 0 HindVP restriction endonuclease Cytidylate_kin PF02224.18 EJS42529.1 - 0.049 13.4 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 EJS42529.1 - 0.051 12.7 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 EJS42529.1 - 0.059 13.1 0.0 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.17 EJS42529.1 - 0.06 13.1 0.0 10 5.8 0.0 2.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 EJS42529.1 - 0.066 12.7 0.0 14 5.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF5584 PF17822.1 EJS42529.1 - 0.076 12.5 0.1 1.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5584) FeoB_N PF02421.18 EJS42529.1 - 0.079 12.5 0.5 1.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP-synt_ab PF00006.25 EJS42529.1 - 0.088 12.5 0.3 2.7 7.6 0.0 3.2 2 2 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 EJS42529.1 - 0.088 12.1 0.0 4.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Septin CLASP_N PF12348.8 EJS42529.1 - 0.098 12.2 1.7 8.6 5.8 0.3 2.5 1 1 1 2 2 2 0 CLASP N terminal AAA_5 PF07728.14 EJS42529.1 - 0.16 12.0 0.0 30 4.6 0.0 3.4 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EJS42529.1 - 0.29 10.9 2.4 7.8 6.2 0.0 2.9 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 EJS42529.1 - 0.29 11.5 2.1 26 5.2 0.3 3.6 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EJS42529.1 - 4.1 5.9 11.8 6.4 5.3 0.0 4.2 5 0 0 5 5 5 0 AAA domain EF-hand_7 PF13499.6 EJS42530.1 - 3.3e-05 24.2 0.6 3.3e-05 24.2 0.6 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EJS42530.1 - 6.6e-05 22.5 1.5 0.077 13.0 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EJS42530.1 - 7.6e-05 22.0 0.5 0.068 12.7 0.1 2.7 2 0 0 2 2 2 2 EF hand Mpv17_PMP22 PF04117.12 EJS42531.1 - 1.7e-25 89.0 3.3 2.7e-25 88.3 3.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ABC1 PF03109.16 EJS42532.1 - 1.8e-34 118.5 0.0 4e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EJS42532.1 - 0.0013 18.3 0.0 0.0084 15.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family bZIP_2 PF07716.15 EJS42533.1 - 0.00012 22.0 4.5 0.00012 22.0 4.5 3.6 3 1 0 3 3 3 1 Basic region leucine zipper TPR_MLP1_2 PF07926.12 EJS42533.1 - 0.0002 21.4 8.7 0.0002 21.4 8.7 2.3 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 EJS42533.1 - 0.0019 18.2 3.2 0.0019 18.2 3.2 3.2 3 1 1 4 4 3 1 bZIP transcription factor Lebercilin PF15619.6 EJS42533.1 - 0.0085 15.8 17.3 0.017 14.8 17.0 1.6 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease TSC22 PF01166.18 EJS42533.1 - 0.013 15.8 1.7 0.013 15.8 1.7 2.9 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF1664 PF07889.12 EJS42533.1 - 0.014 15.4 3.3 0.028 14.5 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 EJS42533.1 - 0.019 15.2 12.5 0.1 12.9 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) FUSC PF04632.12 EJS42533.1 - 0.023 13.3 0.5 0.025 13.1 0.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 EJS42533.1 - 0.1 12.8 14.6 0.035 14.3 11.3 1.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EJS42533.1 - 0.1 11.9 7.2 0.13 11.6 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 EJS42533.1 - 0.12 13.0 20.3 0.1 13.2 17.1 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 EJS42533.1 - 0.14 12.6 13.1 0.18 12.2 13.1 1.2 1 0 0 1 1 1 0 Fez1 AAA_13 PF13166.6 EJS42533.1 - 0.18 10.4 12.6 0.068 11.8 9.7 1.6 1 1 0 1 1 1 0 AAA domain LPP PF04728.13 EJS42533.1 - 0.23 11.9 4.5 3.4 8.1 0.7 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Spc7 PF08317.11 EJS42533.1 - 0.31 9.9 17.2 0.26 10.1 15.2 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein JIP_LZII PF16471.5 EJS42533.1 - 0.36 11.0 15.6 0.15 12.3 4.5 3.9 1 1 3 4 4 4 0 JNK-interacting protein leucine zipper II V_ATPase_I PF01496.19 EJS42533.1 - 0.39 8.6 8.9 0.47 8.3 8.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.11 EJS42533.1 - 0.5 10.6 17.1 2.2 8.6 9.4 3.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.8 EJS42533.1 - 0.62 10.1 20.6 1.2 9.3 9.4 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 EJS42533.1 - 0.62 9.9 13.0 0.77 9.6 12.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Bacillus_HBL PF05791.11 EJS42533.1 - 0.71 9.7 8.4 1.1 9.1 4.0 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TolA_bind_tri PF16331.5 EJS42533.1 - 0.75 9.9 11.8 54 4.0 11.3 2.5 1 1 0 1 1 1 0 TolA binding protein trimerisation YabA PF06156.13 EJS42533.1 - 0.87 10.3 13.4 2.9 8.6 9.4 2.5 1 1 1 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 EJS42533.1 - 1.3 9.0 20.2 0.18 11.8 5.1 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2730 PF10805.8 EJS42533.1 - 1.6 8.9 7.7 6 7.0 1.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Jnk-SapK_ap_N PF09744.9 EJS42533.1 - 1.9 8.7 17.5 1.5 9.0 12.0 2.1 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 BRE1 PF08647.11 EJS42533.1 - 2.5 8.3 14.3 1.1 9.3 8.7 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 EJS42533.1 - 2.6 7.9 12.6 0.19 11.6 3.7 2.9 2 1 1 3 3 3 0 Septum formation initiator SlyX PF04102.12 EJS42533.1 - 2.8 8.6 9.6 15 6.3 3.5 3.1 1 1 1 2 2 2 0 SlyX FlaC_arch PF05377.11 EJS42533.1 - 3.9 7.9 10.9 3.3 8.2 0.7 3.0 2 1 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 EJS42533.1 - 5.5 6.2 12.9 4 6.7 5.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Swi5 PF07061.11 EJS42533.1 - 6.8 6.9 15.4 5.5 7.1 3.1 3.2 2 1 2 4 4 3 0 Swi5 Cnn_1N PF07989.11 EJS42533.1 - 6.8 6.9 18.7 7.3 6.8 1.7 3.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 EJS42533.1 - 7 6.7 20.2 0.87 9.6 5.9 3.1 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding HAUS-augmin3 PF14932.6 EJS42533.1 - 7.7 6.0 16.0 5.1 6.6 11.4 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 UPF0242 PF06785.11 EJS42533.1 - 8.4 6.4 16.8 45 4.1 16.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Glycogen_syn PF05693.13 EJS42534.1 - 0 1101.7 0.0 0 1101.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 EJS42534.1 - 7.1e-10 38.7 0.0 7e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EJS42534.1 - 3.4e-07 30.8 0.0 0.00084 19.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EJS42534.1 - 1.5e-05 25.1 0.1 3.4e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EJS42534.1 - 6.3e-05 23.5 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EJS42534.1 - 0.00055 19.7 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Cpn60_TCP1 PF00118.24 EJS42535.1 - 2.5e-83 280.4 9.0 6.2e-83 279.1 9.0 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DAGK_cat PF00781.24 EJS42536.1 - 6.1e-28 97.0 0.0 1e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ras PF00071.22 EJS42537.1 - 1.4e-57 193.8 0.4 1.7e-57 193.6 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS42537.1 - 9.7e-38 129.1 0.1 1.6e-37 128.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS42537.1 - 4.2e-16 58.9 0.4 4.7e-16 58.7 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EJS42537.1 - 1.5e-05 25.1 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJS42537.1 - 1.6e-05 24.9 0.1 0.079 12.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EJS42537.1 - 2.4e-05 23.8 0.0 4.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EJS42537.1 - 3.8e-05 23.1 0.2 4.9e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EJS42537.1 - 0.00032 20.3 0.0 0.0091 15.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 EJS42537.1 - 0.00086 19.3 0.5 0.0031 17.5 0.1 1.8 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 EJS42537.1 - 0.0036 17.1 0.8 0.03 14.1 0.8 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EJS42537.1 - 0.0054 16.3 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 EJS42537.1 - 0.015 15.1 0.2 0.021 14.6 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EJS42537.1 - 0.021 15.1 0.0 0.065 13.5 0.0 1.8 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EJS42537.1 - 0.032 14.6 0.0 0.062 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 EJS42537.1 - 0.055 12.3 0.2 0.1 11.4 0.1 1.4 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) ResIII PF04851.15 EJS42537.1 - 0.072 13.1 0.2 0.1 12.6 0.2 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 EJS42537.1 - 0.079 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 EJS42537.1 - 0.19 11.4 7.1 4.8 6.8 0.1 2.1 1 1 0 2 2 2 0 AAA ATPase domain TMA7 PF09072.10 EJS42538.1 - 2.3e-24 86.0 19.4 2.5e-24 85.9 19.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF5633 PF18656.1 EJS42538.1 - 0.083 12.8 1.5 0.12 12.3 1.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5633) Ribosomal_S28e PF01200.18 EJS42539.1 - 1.1e-32 111.8 2.7 1.2e-32 111.7 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.12 EJS42539.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region XLF PF09302.11 EJS42540.1 - 8.6e-13 48.8 1.1 1.4e-12 48.2 1.1 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Zein PF01559.16 EJS42541.1 - 0.001 18.7 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 Zein seed storage protein Longin PF13774.6 EJS42542.1 - 7.7e-19 67.5 0.6 2.4e-18 66.0 0.5 1.8 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EJS42542.1 - 2.1e-16 59.5 0.2 4.2e-16 58.5 0.2 1.5 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.12 EJS42542.1 - 0.00027 21.0 0.1 0.00046 20.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Phi-29_GP16_7 PF06720.11 EJS42542.1 - 0.083 12.7 0.7 0.13 12.1 0.7 1.3 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 TBPIP PF07106.13 EJS42542.1 - 0.086 12.8 0.6 0.3 11.1 0.5 2.0 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain DcpS PF05652.12 EJS42543.1 - 1e-35 122.7 0.0 1.6e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EJS42543.1 - 3.7e-34 117.6 0.3 1e-33 116.2 0.1 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Cnd1 PF12717.7 EJS42544.1 - 6.6e-50 169.3 17.2 5.7e-43 146.8 0.1 5.4 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EJS42544.1 - 9.5e-50 168.7 1.5 9.5e-50 168.7 1.5 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 EJS42544.1 - 2e-12 46.2 5.1 0.078 13.3 0.0 6.4 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 EJS42544.1 - 2.9e-10 40.4 0.0 0.0032 17.8 0.0 4.2 3 1 0 3 3 3 2 HEAT repeats Cnd3 PF12719.7 EJS42544.1 - 3.8e-08 32.9 3.5 0.00011 21.5 0.1 3.2 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 EJS42544.1 - 3.9e-06 27.2 0.8 2 9.0 0.0 4.9 4 0 0 4 4 4 2 HEAT-like repeat RTP1_C1 PF10363.9 EJS42544.1 - 0.00017 21.7 1.8 0.064 13.4 0.0 4.2 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 MCM PF00493.23 EJS42545.1 - 1.5e-104 348.0 0.0 3e-104 347.0 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EJS42545.1 - 2.2e-37 127.7 0.1 4.4e-37 126.7 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EJS42545.1 - 6.5e-28 97.0 1.4 2e-27 95.4 1.4 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EJS42545.1 - 7e-17 61.9 0.2 2e-16 60.5 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 EJS42545.1 - 3.6e-06 27.0 0.0 1.3e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EJS42545.1 - 3.9e-06 26.4 0.0 0.00069 19.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EJS42545.1 - 0.00041 20.2 0.1 0.0028 17.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EJS42545.1 - 0.029 14.1 0.0 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA PF00004.29 EJS42545.1 - 0.077 13.4 0.0 0.77 10.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EJS42546.1 - 1.7e-41 141.9 0.6 3.2e-41 141.0 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS42546.1 - 6.9e-30 103.7 0.5 4.6e-29 101.0 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS42546.1 - 1.2e-05 25.4 0.7 8.9e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DnaI_N PF07319.11 EJS42546.1 - 0.013 16.1 4.2 1.3 9.7 0.2 3.2 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus CMS1 PF14617.6 EJS42546.1 - 0.024 14.0 0.1 0.07 12.5 0.1 1.8 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit CFIA_Pcf11 PF11526.8 EJS42546.1 - 0.1 13.1 2.6 0.19 12.2 0.9 2.1 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Microtub_bind PF13931.6 EJS42546.1 - 0.14 12.5 6.1 0.45 10.9 0.5 2.6 2 1 0 2 2 2 0 Kinesin-associated microtubule-binding SecA_DEAD PF07517.14 EJS42546.1 - 0.93 8.7 4.5 9.9 5.3 0.0 2.7 3 0 0 3 3 3 0 SecA DEAD-like domain CPSF73-100_C PF11718.8 EJS42547.1 - 7.9e-53 179.2 1.8 1.3e-52 178.5 1.8 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EJS42547.1 - 1.8e-28 99.0 0.0 4.2e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 EJS42547.1 - 3.9e-24 85.8 0.2 7.5e-24 84.8 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EJS42547.1 - 1.3e-19 70.4 0.0 2.7e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EJS42547.1 - 3.1e-19 68.7 0.0 6.6e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EJS42547.1 - 7.4e-07 28.9 0.0 1.7e-05 24.5 0.1 2.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EJS42547.1 - 2.7e-05 24.1 0.1 0.00014 21.8 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EJS42547.1 - 0.057 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative beta-lactamase-like family Fungal_trans PF04082.18 EJS42548.1 - 8.9e-23 80.7 7.1 8.9e-23 80.7 7.1 2.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS42548.1 - 1.7e-06 28.0 10.6 4.1e-06 26.8 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RF-1 PF00472.20 EJS42549.1 - 1.1e-18 67.3 4.1 1.8e-18 66.6 4.1 1.4 1 1 0 1 1 1 1 RF-1 domain Tautomerase_2 PF14552.6 EJS42549.1 - 0.16 12.0 2.3 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme DUF1640 PF07798.11 EJS42550.1 - 1.4e-21 77.3 5.6 2.5e-21 76.5 5.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) OAD_gamma PF04277.13 EJS42550.1 - 0.055 14.1 0.7 1.8 9.2 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S49_N PF08496.10 EJS42550.1 - 7 6.7 7.5 28 4.7 0.4 3.1 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Methyltransf_16 PF10294.9 EJS42551.1 - 8.6e-13 48.4 0.0 1.2e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EJS42551.1 - 9.4e-05 22.3 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS42551.1 - 0.034 14.8 0.1 0.7 10.6 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EJS42551.1 - 0.077 13.7 0.0 1.7 9.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Hus1 PF04005.12 EJS42552.1 - 1.5e-21 76.8 0.2 6.3e-15 55.1 0.0 2.3 2 0 0 2 2 2 2 Hus1-like protein GTP_EFTU PF00009.27 EJS42553.1 - 3.8e-52 176.7 0.1 2.8e-51 173.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EJS42553.1 - 2.2e-42 143.5 6.9 6.3e-42 142.1 6.9 1.8 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EJS42553.1 - 4.2e-18 65.2 0.0 1.1e-17 63.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EJS42553.1 - 1.3e-08 35.1 1.7 3e-08 33.9 1.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EJS42553.1 - 2.6e-05 24.3 0.6 9.4e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EJS42553.1 - 0.012 15.0 0.0 0.26 10.7 0.0 2.4 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit RF3_C PF16658.5 EJS42553.1 - 0.015 15.2 0.1 0.058 13.2 0.0 2.0 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain Epimerase PF01370.21 EJS42554.1 - 2.6e-06 27.1 0.0 5.6e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EJS42554.1 - 9e-06 25.7 0.0 3.6e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EJS42554.1 - 2.1e-05 23.7 0.0 3.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EJS42554.1 - 0.00015 21.3 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EJS42554.1 - 0.0012 18.0 0.0 0.066 12.4 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 EJS42554.1 - 0.006 16.5 0.0 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 KR domain SMRP1 PF15181.6 EJS42554.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 RmlD_sub_bind PF04321.17 EJS42554.1 - 0.029 13.5 0.0 0.11 11.5 0.0 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain Choline_kin_N PF04428.14 EJS42554.1 - 0.072 12.8 0.1 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Choline kinase N terminus GDP_Man_Dehyd PF16363.5 EJS42554.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EJS42554.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family IF-2B PF01008.17 EJS42555.1 - 3.5e-93 311.9 0.1 4.4e-93 311.5 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1804 PF08822.11 EJS42555.1 - 0.0015 18.5 0.0 0.0044 17.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1804) TPR_2 PF07719.17 EJS42556.1 - 5.1e-08 32.5 0.3 2.4e-05 24.1 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EJS42556.1 - 2.4e-07 30.3 0.2 7.5e-05 22.4 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJS42556.1 - 1.6e-05 25.3 2.1 2.2e-05 24.9 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJS42556.1 - 2.5e-05 24.5 0.7 0.0034 17.6 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EJS42556.1 - 0.00013 22.5 0.9 0.00033 21.2 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EJS42556.1 - 0.0023 18.0 0.2 0.037 14.2 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJS42556.1 - 0.011 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_15 PF13429.6 EJS42556.1 - 0.012 14.8 0.1 0.023 13.9 0.0 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EJS42556.1 - 0.018 15.2 0.2 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EJS42556.1 - 0.061 14.0 0.2 0.14 12.9 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EJS42556.1 - 0.089 12.9 0.7 0.74 9.9 0.1 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EJS42556.1 - 0.1 13.3 0.2 0.43 11.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_6 PF12774.7 EJS42556.1 - 0.13 11.2 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TPR_9 PF13371.6 EJS42556.1 - 0.18 11.9 1.3 0.66 10.2 0.2 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Ras PF00071.22 EJS42557.1 - 1.5e-51 174.2 0.0 1.9e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS42557.1 - 1.3e-31 109.3 0.1 3.6e-31 107.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS42557.1 - 5e-12 45.6 0.0 7e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 EJS42557.1 - 0.00028 21.3 0.2 0.0023 18.3 0.2 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 EJS42557.1 - 0.00039 20.5 0.0 0.00089 19.3 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EJS42557.1 - 0.0012 18.3 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EJS42557.1 - 0.0017 17.9 0.4 0.0073 15.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EJS42557.1 - 0.01 15.3 0.0 0.017 14.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EJS42557.1 - 0.016 14.4 2.6 1.4 8.0 0.1 2.9 2 1 1 3 3 3 0 G-protein alpha subunit ATPase PF06745.13 EJS42557.1 - 0.019 14.3 0.2 0.031 13.6 0.2 1.3 1 0 0 1 1 1 0 KaiC Pox_A32 PF04665.12 EJS42557.1 - 0.02 14.4 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 EJS42557.1 - 0.021 14.8 0.1 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EJS42557.1 - 0.03 13.9 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ArgoMid PF16487.5 EJS42557.1 - 0.046 14.0 0.7 0.069 13.4 0.1 1.7 2 0 0 2 2 1 0 Mid domain of argonaute AAA_24 PF13479.6 EJS42557.1 - 0.066 12.9 0.3 0.1 12.3 0.3 1.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EJS42557.1 - 0.082 12.9 0.1 0.22 11.6 0.1 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EJS42557.1 - 0.1 12.8 0.6 0.22 11.7 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EJS42557.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EJS42557.1 - 0.14 11.4 0.3 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Septin ATP_sub_h PF10775.9 EJS42558.1 - 2e-23 82.1 0.4 2.7e-23 81.7 0.4 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h zf-U1 PF06220.12 EJS42559.1 - 1.2e-18 66.5 5.6 1.2e-18 66.5 5.6 1.8 2 0 0 2 2 2 1 U1 zinc finger G_glu_transpept PF01019.21 EJS42560.1 - 2.2e-150 501.8 0.0 2.6e-150 501.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cellulase PF00150.18 EJS42561.1 - 1.1e-13 51.2 0.3 2.6e-13 50.1 0.1 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HRI1 PF16815.5 EJS42562.1 - 1.4e-43 149.2 0.0 1.6e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 PQ-loop PF04193.14 EJS42562.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 PQ loop repeat Cys_Met_Meta_PP PF01053.20 EJS42563.1 - 1.2e-150 501.3 0.0 1.4e-150 501.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EJS42563.1 - 1.9e-09 37.2 0.0 2.6e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EJS42563.1 - 2.2e-08 33.5 0.1 3.6e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EJS42563.1 - 8.2e-08 31.9 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EJS42563.1 - 1.8e-07 30.7 0.0 3.6e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EJS42563.1 - 0.00016 20.3 0.1 0.00027 19.6 0.1 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 EJS42563.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Asparaginase_C PF17763.1 EJS42563.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Aconitase PF00330.20 EJS42564.1 - 1.4e-151 505.6 0.0 1.8e-151 505.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EJS42564.1 - 7.3e-49 165.4 0.0 1.3e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain PI3_PI4_kinase PF00454.27 EJS42565.1 - 2.3e-43 148.8 0.0 5.1e-41 141.1 0.0 2.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EJS42565.1 - 1.3e-39 135.6 0.1 2.7e-39 134.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) GRIP PF01465.20 EJS42567.1 - 2.4e-13 49.8 0.4 8e-13 48.1 0.4 2.0 1 0 0 1 1 1 1 GRIP domain MscS_porin PF12795.7 EJS42567.1 - 0.00018 21.1 23.5 0.00018 21.1 23.5 7.2 3 3 3 7 7 7 3 Mechanosensitive ion channel porin domain Spc7 PF08317.11 EJS42567.1 - 0.022 13.7 152.5 0.046 12.6 15.1 7.6 1 1 5 7 7 7 0 Spc7 kinetochore protein ATG16 PF08614.11 EJS42567.1 - 0.099 12.9 136.5 0.037 14.3 25.8 7.6 1 1 6 7 7 7 0 Autophagy protein 16 (ATG16) Septin PF00735.18 EJS42569.1 - 1.1e-119 398.9 4.2 1.1e-119 398.9 4.2 2.0 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.27 EJS42569.1 - 7.6e-05 22.3 5.3 0.00035 20.2 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EJS42569.1 - 0.0013 19.2 0.0 0.0013 19.2 0.0 2.7 3 0 0 3 3 2 1 ABC transporter AAA_22 PF13401.6 EJS42569.1 - 0.0013 19.0 0.1 0.0064 16.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EJS42569.1 - 0.0034 17.6 0.0 0.085 13.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EJS42569.1 - 0.02 15.2 0.3 0.069 13.4 0.0 2.0 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 EJS42569.1 - 0.02 15.3 0.0 0.065 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EJS42569.1 - 0.028 14.3 3.1 0.41 10.5 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase RNA_helicase PF00910.22 EJS42569.1 - 0.033 14.6 0.2 0.66 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Nas2_N PF18265.1 EJS42569.1 - 0.069 13.1 4.2 0.91 9.5 0.0 3.4 2 1 2 4 4 4 0 Nas2 N_terminal domain AAA PF00004.29 EJS42569.1 - 0.1 13.0 0.1 0.7 10.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EJS42569.1 - 0.13 12.3 2.9 0.53 10.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 EJS42569.1 - 0.2 11.2 7.4 0.41 10.2 7.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMR_HSR1 PF01926.23 EJS42569.1 - 0.28 11.3 4.2 0.14 12.2 0.3 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 EJS42569.1 - 3.7 7.8 5.4 2.2 8.5 0.7 2.8 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 EJS42569.1 - 5.7 6.6 9.5 0.26 11.1 1.8 2.6 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SNF5 PF04855.12 EJS42570.1 - 2.5e-46 158.4 3.2 2.3e-25 89.8 0.2 2.4 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 FXR_C3 PF16097.5 EJS42570.1 - 0.079 13.7 6.5 11 6.7 0.3 3.5 3 0 0 3 3 3 0 Fragile X-related 1 protein C-terminal region 3 DUF4296 PF14129.6 EJS42570.1 - 9.7 6.9 7.9 1.9 9.2 1.6 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4296) zf-CCCH PF00642.24 EJS42571.1 - 2.7e-10 39.9 3.3 6.1e-10 38.8 3.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EJS42571.1 - 1.3e-08 34.5 7.0 2.5e-08 33.6 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJS42571.1 - 4.3e-08 32.9 7.2 7.7e-08 32.1 7.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EJS42571.1 - 8.7e-08 31.9 8.0 8.7e-08 31.9 8.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJS42571.1 - 4.6e-07 29.7 10.8 8.5e-07 28.8 10.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 EJS42571.1 - 7e-06 25.9 5.6 7e-06 25.9 5.6 2.3 2 0 0 2 2 2 1 Zinc finger domain zf-C3HC4 PF00097.25 EJS42571.1 - 2.5e-05 24.0 7.7 4.8e-05 23.2 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJS42571.1 - 0.00012 22.4 8.5 0.00026 21.2 8.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EJS42571.1 - 0.00016 21.6 9.1 0.00037 20.4 9.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH_4 PF18044.1 EJS42571.1 - 0.00053 19.7 2.2 0.00053 19.7 2.2 2.6 2 0 0 2 2 2 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 EJS42571.1 - 0.0053 16.9 8.6 0.011 15.8 8.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EJS42571.1 - 0.013 15.6 6.1 0.031 14.4 6.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-CCCH_2 PF14608.6 EJS42571.1 - 0.096 13.2 1.9 0.096 13.2 1.9 1.8 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger zf-P11 PF03854.14 EJS42571.1 - 0.82 9.4 5.1 1.8 8.3 5.1 1.5 1 0 0 1 1 1 0 P-11 zinc finger Pex24p PF06398.11 EJS42572.1 - 5.2e-92 308.6 10.3 8.2e-92 308.0 10.3 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribosomal_L38e PF01781.18 EJS42573.1 - 8.5e-27 93.1 2.5 9.4e-27 92.9 2.5 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family HABP4_PAI-RBP1 PF04774.15 EJS42574.1 - 0.00053 20.8 1.0 0.00062 20.6 1.0 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family CTP_transf_like PF01467.26 EJS42575.1 - 1.5e-32 112.8 0.0 2.1e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Mid2 PF04478.12 EJS42576.1 - 2.8e-69 231.7 2.0 2.8e-69 231.7 2.0 3.4 2 1 2 4 4 4 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 EJS42576.1 - 0.0079 15.6 2.4 0.0079 15.6 2.4 2.9 2 1 0 2 2 2 1 Transmembrane alpha-helix domain LAP1C PF05609.12 EJS42576.1 - 0.012 14.8 15.3 0.022 13.9 15.3 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MRAP PF15183.6 EJS42576.1 - 0.03 14.3 0.0 0.098 12.6 0.0 1.9 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Ribosomal_S25 PF03297.15 EJS42577.1 - 8.5e-39 131.8 6.1 9.5e-39 131.7 6.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 EJS42577.1 - 0.0002 21.1 0.1 0.00029 20.5 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain EAP30 PF04157.16 EJS42577.1 - 0.035 13.4 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_CodY PF08222.11 EJS42577.1 - 0.052 13.1 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain Ribosomal_L10 PF00466.20 EJS42578.1 - 3e-24 85.0 0.2 5.5e-24 84.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 EJS42578.1 - 1.1e-20 74.0 2.5 1.1e-20 74.0 2.5 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 EJS42578.1 - 5e-20 71.3 0.0 7.9e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Glucan_synthase PF02364.15 EJS42579.1 - 0 1352.5 0.0 0 1351.7 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EJS42579.1 - 2.4e-43 147.5 0.3 8e-43 145.9 0.3 2.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.14 EJS42580.1 - 6e-139 462.7 1.0 7.8e-139 462.3 1.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EJS42580.1 - 5e-17 62.4 0.8 1.2e-16 61.1 0.8 1.7 1 0 0 1 1 1 1 X8 domain HEAT PF02985.22 EJS42582.1 - 2.8e-15 55.1 15.6 0.00032 20.7 0.0 10.6 12 0 0 12 12 11 3 HEAT repeat IBN_N PF03810.19 EJS42582.1 - 9.3e-13 47.9 3.1 3e-10 39.9 1.9 4.2 3 1 1 4 4 4 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 EJS42582.1 - 2.5e-12 47.0 13.4 1.9e-08 34.6 0.0 9.1 9 2 2 11 11 11 1 HEAT-like repeat Cnd1 PF12717.7 EJS42582.1 - 1.1e-07 32.0 4.3 0.011 15.8 0.0 5.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EJS42582.1 - 3e-07 30.7 5.0 0.034 14.5 0.0 6.7 5 2 3 8 8 8 2 HEAT repeats DUF3385 PF11865.8 EJS42582.1 - 6.2e-06 26.2 3.9 0.41 10.6 0.0 5.2 2 2 3 6 6 6 2 Domain of unknown function (DUF3385) CLASP_N PF12348.8 EJS42582.1 - 0.0016 18.0 2.4 1.1 8.8 0.0 4.5 4 1 1 5 5 5 1 CLASP N terminal Arm PF00514.23 EJS42582.1 - 0.0019 18.2 5.9 0.053 13.6 0.0 5.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 EJS42582.1 - 0.0043 16.8 0.5 3.4 7.4 0.0 4.3 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EJS42582.1 - 0.031 14.9 1.4 14 6.3 0.0 4.4 4 0 0 4 4 3 0 Vacuolar 14 Fab1-binding region Sec7_N PF12783.7 EJS42582.1 - 0.036 14.0 0.5 3.2 7.6 0.1 3.1 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TIP120 PF08623.10 EJS42582.1 - 0.09 12.5 0.0 5.2 6.8 0.0 3.0 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) Mito_carr PF00153.27 EJS42583.1 - 2.3e-55 184.5 1.3 2.3e-19 69.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CN_hydrolase PF00795.22 EJS42584.1 - 9.8e-68 228.3 0.0 1.1e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1415 PF07209.12 EJS42584.1 - 0.046 13.5 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) LRR_4 PF12799.7 EJS42585.1 - 2.5e-05 24.5 10.5 0.015 15.7 0.3 4.9 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EJS42585.1 - 0.0053 16.6 1.4 4 7.4 0.0 3.0 3 0 0 3 3 3 2 F-box-like LRR_8 PF13855.6 EJS42585.1 - 0.0067 16.2 5.0 0.36 10.6 0.2 4.5 3 1 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 EJS42585.1 - 0.053 13.6 6.9 49 4.3 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich repeat GPS2_interact PF15784.5 EJS42585.1 - 0.38 11.2 2.3 0.6 10.6 0.6 2.1 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain LRR_1 PF00560.33 EJS42585.1 - 0.73 10.6 8.2 1.8e+02 3.3 0.4 6.2 4 2 1 5 5 5 0 Leucine Rich Repeat TAL_FSA PF00923.19 EJS42587.1 - 2.1e-99 332.5 0.0 2.4e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase YajC PF02699.15 EJS42587.1 - 0.051 13.4 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Preprotein translocase subunit IlvN PF07991.12 EJS42588.1 - 6.7e-46 155.9 0.0 9.2e-46 155.4 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EJS42588.1 - 1.3e-40 139.0 0.0 2.1e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Bromodomain PF00439.25 EJS42590.1 - 2.1e-25 88.6 4.3 7.2e-12 45.2 0.2 3.1 3 0 0 3 3 3 2 Bromodomain BAH PF01426.18 EJS42590.1 - 2.6e-25 88.6 0.2 1.2e-24 86.4 0.0 2.2 2 0 0 2 2 2 1 BAH domain Lyase_1 PF00206.20 EJS42591.1 - 7.6e-25 87.9 0.0 1.6e-24 86.9 0.0 1.5 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 EJS42591.1 - 5.5e-17 62.1 0.0 2.3e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 EJS42591.1 - 0.071 12.8 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) VPS38 PF17649.1 EJS42592.1 - 1.8e-176 587.2 22.1 2.1e-176 587.0 22.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 38 Atg14 PF10186.9 EJS42592.1 - 0.0053 15.9 0.7 0.0053 15.9 0.7 2.2 1 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 EJS42592.1 - 0.01 15.8 1.5 0.014 15.4 0.1 1.9 2 0 0 2 2 2 0 Apg6 BARA domain TBD PF12845.7 EJS42592.1 - 0.01 15.7 0.0 7.9 6.5 0.0 3.2 3 0 0 3 3 3 0 TBD domain DUF2408 PF10303.9 EJS42592.1 - 0.037 14.6 4.1 0.11 13.1 4.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PIN_4 PF13638.6 EJS42594.1 - 0.0028 18.0 0.0 0.0074 16.6 0.0 1.7 2 1 0 2 2 2 1 PIN domain DUF2462 PF09495.10 EJS42595.1 - 7.5e-15 55.4 12.7 1.1e-14 54.9 12.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Glutaredoxin PF00462.24 EJS42596.1 - 4.9e-05 23.5 0.0 7.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 EJS42596.1 - 0.0079 16.0 0.0 0.0095 15.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 EJS42596.1 - 0.019 14.6 0.5 0.025 14.2 0.5 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) F-box-like PF12937.7 EJS42597.1 - 0.00021 21.1 0.9 0.00064 19.6 0.9 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJS42597.1 - 0.0024 17.7 0.9 0.005 16.7 0.9 1.6 1 0 0 1 1 1 1 F-box domain HSR PF03172.13 EJS42597.1 - 0.082 13.1 0.9 2 8.6 0.0 3.5 4 0 0 4 4 4 0 HSR domain P21-Arc PF04062.14 EJS42598.1 - 3.1e-74 248.7 0.1 3.5e-74 248.6 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CNH PF00780.22 EJS42599.1 - 3e-81 273.1 1.2 3.9e-81 272.7 0.3 1.7 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EJS42599.1 - 9.8e-40 135.8 0.0 9.8e-40 135.8 0.0 3.2 2 1 1 3 3 3 1 Pleckstrin homology domain RhoGEF PF00621.20 EJS42599.1 - 3.1e-30 105.8 0.0 3.1e-30 105.8 0.0 2.8 4 0 0 4 4 4 1 RhoGEF domain DEP PF00610.21 EJS42599.1 - 7.9e-15 54.7 0.0 1.9e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ELO PF01151.18 EJS42600.1 - 1.2e-62 211.8 27.3 1.5e-62 211.4 27.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family zf-BED PF02892.15 EJS42601.1 - 0.098 12.7 0.3 0.23 11.5 0.3 1.7 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.6 EJS42602.1 - 9.6e-06 26.0 27.9 0.00039 21.0 2.6 4.9 5 0 0 5 5 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJS42602.1 - 0.00051 20.3 2.6 0.045 14.0 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EJS42602.1 - 0.00095 19.1 1.4 0.00095 19.1 1.4 3.6 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 EJS42602.1 - 0.0016 18.8 4.3 0.0016 18.8 4.3 4.9 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-SNAP50_C PF12251.8 EJS42602.1 - 0.008 15.9 6.4 0.023 14.4 0.7 2.2 2 0 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal Zn-C2H2_12 PF18112.1 EJS42602.1 - 0.013 16.0 0.3 7.2 7.2 0.1 3.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_3 PF13920.6 EJS42602.1 - 0.016 15.0 5.9 1.6 8.7 0.3 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_2 PF13465.6 EJS42602.1 - 0.035 14.6 4.0 0.035 14.6 4.0 5.0 4 1 1 5 5 5 0 Zinc-finger double domain zf-DBF PF07535.12 EJS42602.1 - 0.16 12.1 1.5 7.1 6.8 0.2 3.2 3 0 0 3 3 3 0 DBF zinc finger zf-RING_5 PF14634.6 EJS42602.1 - 0.34 10.9 5.9 9.1 6.3 0.3 3.4 3 0 0 3 3 3 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EJS42602.1 - 0.35 10.8 5.4 4.1 7.3 0.2 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 EJS42602.1 - 0.36 10.7 2.7 1.7 8.6 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_9 PF14369.6 EJS42602.1 - 0.62 10.4 4.2 1.6 9.0 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon Prok-RING_1 PF14446.6 EJS42602.1 - 0.69 9.9 5.1 5.2 7.1 0.0 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 EJS42602.1 - 0.71 10.3 7.6 20 5.6 0.7 3.6 3 0 0 3 3 3 0 Ring finger domain zf-C2HC_2 PF13913.6 EJS42602.1 - 0.73 9.8 11.6 2.1 8.3 0.9 3.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 EJS42602.1 - 0.82 10.0 12.0 0.2 12.0 4.5 3.5 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 EJS42602.1 - 2.1 8.6 7.1 36 4.6 0.4 3.6 3 0 0 3 3 3 0 Zinc ribbon domain PSY3 PF16836.5 EJS42603.1 - 4.1e-75 252.1 1.4 4.7e-75 251.9 1.4 1.0 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description FBPase PF00316.20 EJS42604.1 - 2.3e-86 288.1 0.1 3e-86 287.7 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain SecY PF00344.20 EJS42605.1 - 2.6e-62 210.8 15.9 3.5e-62 210.4 15.9 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EJS42605.1 - 7.8e-18 64.0 0.2 5.5e-17 61.3 0.2 2.6 1 0 0 1 1 1 1 Plug domain of Sec61p SdpI PF13630.6 EJS42605.1 - 0.21 11.7 0.2 0.21 11.7 0.2 2.8 3 0 0 3 3 3 0 SdpI/YhfL protein family Cation_ATPase_C PF00689.21 EJS42605.1 - 3.3 7.4 12.5 1.5 8.5 0.5 3.3 2 1 0 3 3 3 0 Cation transporting ATPase, C-terminus CRAL_TRIO PF00650.20 EJS42606.1 - 2.7e-43 147.4 0.1 4.7e-43 146.6 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJS42606.1 - 1.3e-09 38.1 0.1 3.5e-09 36.7 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EJS42606.1 - 7.8e-05 22.9 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Chlorophyllase2 PF12740.7 EJS42606.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme tRNA-synt_1 PF00133.22 EJS42608.1 - 3.9e-55 187.2 1.0 1.2e-32 113.0 4.8 6.4 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EJS42608.1 - 1.9e-40 138.4 0.0 3.1e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EJS42608.1 - 1.2e-31 109.9 0.3 2.6e-21 75.9 0.0 5.0 4 1 1 5 5 5 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EJS42608.1 - 0.00012 22.1 0.3 0.00027 20.9 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EJS42608.1 - 0.00039 19.9 0.0 0.13 11.6 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 EJS42608.1 - 0.0021 17.0 0.0 0.0048 15.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (R) DNA_ligase_ZBD PF03119.16 EJS42608.1 - 0.04 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.6 EJS42608.1 - 0.11 12.0 4.1 1.2 8.6 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EJS42608.1 - 0.28 11.3 0.9 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain AAA_23 PF13476.6 EJS42609.1 - 9.9e-20 71.9 7.3 9.9e-20 71.9 7.3 5.6 3 2 3 6 6 6 1 AAA domain SMC_N PF02463.19 EJS42609.1 - 3e-17 62.8 38.3 1.2e-16 60.8 38.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EJS42609.1 - 6e-10 39.4 30.1 6e-10 39.4 30.1 4.3 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 EJS42609.1 - 1.9e-06 27.9 17.5 0.001 19.0 0.3 3.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system KxDL PF10241.9 EJS42609.1 - 0.00056 20.1 1.0 0.00056 20.1 1.0 8.3 7 1 0 8 8 8 3 Uncharacterized conserved protein AAA_29 PF13555.6 EJS42609.1 - 0.00066 19.4 0.1 0.0023 17.6 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 EJS42609.1 - 0.035 14.0 0.7 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF1664 PF07889.12 EJS42609.1 - 0.1 12.6 52.8 0.3 11.1 3.1 6.8 3 2 4 8 8 8 0 Protein of unknown function (DUF1664) Filament PF00038.21 EJS42609.1 - 0.52 9.8 81.2 0.02 14.5 32.8 3.8 3 1 0 3 3 3 0 Intermediate filament protein Mac PF12464.8 EJS42609.1 - 5.2 7.4 7.6 2 8.7 1.4 3.3 2 0 0 2 2 2 0 Maltose acetyltransferase Vac14_Fig4_bd PF11916.8 EJS42610.1 - 2e-66 223.0 5.5 5e-66 221.8 5.5 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EJS42610.1 - 2.6e-46 156.1 0.3 3.9e-38 130.0 0.1 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EJS42610.1 - 7.1e-10 38.3 5.0 0.0014 18.8 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 EJS42610.1 - 1.9e-08 34.6 0.2 0.16 12.5 0.0 6.0 6 0 0 6 6 6 2 HEAT-like repeat CLASP_N PF12348.8 EJS42610.1 - 4.5e-06 26.4 3.9 0.12 11.9 1.9 4.4 4 0 0 4 4 4 2 CLASP N terminal RIX1 PF08167.12 EJS42610.1 - 0.00085 19.1 3.9 0.033 13.9 0.1 4.0 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis ParcG PF10274.9 EJS42610.1 - 0.02 15.0 5.2 0.76 9.9 0.4 3.5 4 0 0 4 4 4 0 Parkin co-regulated protein Arm PF00514.23 EJS42610.1 - 0.044 13.8 4.7 3.3 7.9 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EJS42610.1 - 0.24 11.6 5.4 6.3 7.0 0.3 4.1 3 3 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-C2H2_2 PF12756.7 EJS42611.1 - 2.6e-31 108.0 6.9 2.3e-29 101.7 2.1 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) DUF2024 PF09630.10 EJS42611.1 - 0.11 12.4 0.3 0.44 10.5 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Ribosomal_S14 PF00253.21 EJS42612.1 - 8.7e-15 54.2 3.6 9.5e-15 54.1 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 EJS42612.1 - 0.048 13.6 0.2 0.054 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Prim_Zn_Ribbon PF08273.12 EJS42612.1 - 0.057 13.7 2.3 1 9.7 0.3 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase CFEM PF05730.11 EJS42613.1 - 2.6e-09 37.0 13.6 7.1e-09 35.6 13.6 1.8 1 0 0 1 1 1 1 CFEM domain GREB1 PF15782.5 EJS42613.1 - 1.8 5.6 29.7 1.8 5.6 29.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOBP PF15279.6 EJS42613.1 - 7.7 7.0 24.7 11 6.5 24.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Arrestin_N PF00339.29 EJS42614.1 - 7.8e-05 22.8 0.1 0.00029 20.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ATP-synt_10 PF05176.14 EJS42615.1 - 1e-93 313.3 1.1 1.1e-93 313.1 1.1 1.0 1 0 0 1 1 1 1 ATP10 protein COX7C PF02935.16 EJS42616.1 - 5.7e-24 84.2 1.2 6.8e-24 83.9 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Sec1 PF00995.23 EJS42617.1 - 4.8e-82 277.0 11.2 5.4e-82 276.9 11.2 1.0 1 0 0 1 1 1 1 Sec1 family AAA PF00004.29 EJS42618.1 - 3.4e-90 299.3 0.0 1.3e-43 148.6 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS42618.1 - 4.5e-27 93.6 0.4 2.2e-14 53.0 0.2 2.5 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EJS42618.1 - 1.9e-13 50.4 0.0 1.2e-05 25.2 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EJS42618.1 - 7.1e-12 46.0 0.3 1.8e-05 25.2 0.0 4.0 3 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EJS42618.1 - 2.9e-11 43.5 0.2 4.3e-05 23.5 0.0 3.8 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EJS42618.1 - 9.7e-10 38.8 0.0 0.00011 22.4 0.0 2.9 2 2 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EJS42618.1 - 3e-08 34.0 1.0 0.0027 18.0 0.0 4.2 2 2 2 4 4 4 1 AAA domain AAA_33 PF13671.6 EJS42618.1 - 1.1e-07 32.0 0.0 0.00099 19.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EJS42618.1 - 3.5e-07 30.3 0.0 0.001 19.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EJS42618.1 - 2.2e-06 27.1 0.0 0.0067 15.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Rad17 PF03215.15 EJS42618.1 - 5.7e-06 26.4 0.0 0.0094 15.9 0.0 2.7 2 1 0 2 2 2 2 Rad17 P-loop domain RNA_helicase PF00910.22 EJS42618.1 - 9.1e-06 26.0 0.0 0.16 12.4 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 EJS42618.1 - 3.8e-05 23.4 4.7 0.3 10.6 0.1 4.0 2 2 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EJS42618.1 - 5.9e-05 22.5 0.1 0.16 11.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EJS42618.1 - 8.4e-05 22.9 0.0 0.4 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EJS42618.1 - 0.00025 21.0 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EJS42618.1 - 0.00038 20.3 0.0 0.066 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EJS42618.1 - 0.00054 19.5 0.0 1.1 8.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region Bac_DnaA PF00308.18 EJS42618.1 - 0.002 18.0 0.0 0.07 13.0 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_30 PF13604.6 EJS42618.1 - 0.0021 17.8 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EJS42618.1 - 0.0023 17.8 0.0 2.8 7.8 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EJS42618.1 - 0.0033 18.0 0.0 0.42 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 EJS42618.1 - 0.0035 17.5 0.0 0.52 10.4 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain CDC48_N PF02359.18 EJS42618.1 - 0.0049 17.0 0.0 0.028 14.6 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain NACHT PF05729.12 EJS42618.1 - 0.0054 16.7 0.4 0.11 12.4 0.0 3.0 3 0 0 3 3 3 1 NACHT domain ABC_tran PF00005.27 EJS42618.1 - 0.006 17.1 0.1 0.19 12.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 EJS42618.1 - 0.0067 16.2 0.0 4.2 7.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 EJS42618.1 - 0.01 15.2 0.4 13 5.0 0.0 3.4 2 1 0 3 3 3 0 KaiC T2SSE PF00437.20 EJS42618.1 - 0.011 14.8 0.4 3.6 6.6 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 EJS42618.1 - 0.015 15.1 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 EJS42618.1 - 0.015 15.0 0.1 9.1 6.0 0.0 3.9 4 1 0 4 4 3 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EJS42618.1 - 0.015 15.2 0.0 7.4 6.4 0.0 3.2 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EJS42618.1 - 0.016 15.0 0.0 0.83 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EJS42618.1 - 0.027 13.7 0.2 3 7.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 EJS42618.1 - 0.045 12.9 0.0 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 EJS42618.1 - 0.1 13.0 1.5 1 9.7 0.1 2.7 2 1 0 2 2 2 0 AAA domain Desmo_N PF06771.11 EJS42618.1 - 0.11 12.9 0.1 21 5.5 0.0 2.8 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus AFG1_ATPase PF03969.16 EJS42618.1 - 0.16 10.9 0.0 0.35 9.7 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase DSHCT PF08148.12 EJS42619.1 - 3.9e-46 156.7 0.2 3.9e-46 156.7 0.2 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EJS42619.1 - 5.9e-40 136.2 0.1 1.5e-39 134.9 0.1 1.6 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 EJS42619.1 - 1.3e-20 74.0 0.1 2.6e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 EJS42619.1 - 1.3e-17 64.6 5.1 4.9e-17 62.7 5.1 2.0 1 0 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.15 EJS42619.1 - 1.3e-07 31.8 0.0 3.6e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EJS42619.1 - 4.4e-07 30.2 0.0 2.7e-06 27.7 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EJS42619.1 - 0.027 14.8 0.0 0.54 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pox_RNA_Pol_19 PF05320.12 EJS42619.1 - 0.25 11.3 0.0 0.25 11.3 0.0 2.8 3 0 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Bromodomain PF00439.25 EJS42620.1 - 3.8e-38 129.4 0.9 1.1e-19 70.3 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EJS42620.1 - 3.1e-20 72.1 1.3 3.1e-20 72.1 1.3 2.3 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation zf-C2H2 PF00096.26 EJS42621.1 - 0.00056 20.2 16.2 0.039 14.4 1.0 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EJS42621.1 - 0.0037 17.4 0.2 0.0037 17.4 0.2 3.8 5 0 0 5 5 5 2 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 EJS42621.1 - 0.033 14.5 3.6 3.2 8.2 0.1 3.1 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EJS42621.1 - 0.047 14.1 16.5 0.17 12.3 1.0 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJS42621.1 - 0.058 14.3 0.6 0.058 14.3 0.6 4.3 5 0 0 5 5 5 0 C2H2-type zinc finger DNA_pol_phi PF04931.13 EJS42621.1 - 0.63 8.1 13.7 1.1 7.3 13.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi Utp21 PF04192.12 EJS42622.1 - 1.8e-78 263.3 1.8 2.6e-78 262.7 1.8 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EJS42622.1 - 1.8e-17 63.4 0.0 0.00024 21.4 0.0 5.9 3 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJS42622.1 - 3.5e-13 49.8 17.2 7.3e-07 29.8 0.3 8.3 8 0 0 8 8 8 3 WD domain, G-beta repeat eIF2A PF08662.11 EJS42622.1 - 0.0001 22.2 0.1 1.2 9.0 0.0 3.5 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 EJS42622.1 - 0.0003 20.4 0.0 0.011 15.3 0.0 3.1 2 1 2 4 4 4 1 PQQ-like domain SGL PF08450.12 EJS42622.1 - 0.0035 16.9 0.4 13 5.3 0.0 4.4 4 1 1 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region Cytochrom_D1 PF02239.16 EJS42622.1 - 0.042 12.4 0.0 0.33 9.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ctr PF04145.15 EJS42623.1 - 9.8e-36 123.6 0.4 1.8e-35 122.8 0.4 1.4 1 1 0 1 1 1 1 Ctr copper transporter family DUF3010 PF11215.8 EJS42623.1 - 0.17 12.2 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) SRR1 PF07985.12 EJS42624.1 - 5.9e-16 58.2 0.0 9.4e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 SRR1 SUR7 PF06687.12 EJS42625.1 - 5.3e-10 39.3 25.8 1.5e-08 34.6 25.8 3.0 1 1 0 1 1 1 1 SUR7/PalI family EF-G-binding_N PF07299.11 EJS42625.1 - 6.1 7.4 5.9 3.5 8.2 1.1 3.0 2 1 1 3 3 3 0 Elongation factor G-binding protein, N-terminal Goodbye PF17109.5 EJS42625.1 - 7.2 7.1 8.1 4.7 7.7 0.2 3.3 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain SUR7 PF06687.12 EJS42626.1 - 1.6e-43 148.8 15.2 1.9e-43 148.6 15.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF4231 PF14015.6 EJS42626.1 - 0.98 9.9 4.5 0.68 10.4 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Fig1 PF12351.8 EJS42626.1 - 1.2 9.0 12.1 0.35 10.8 8.5 1.9 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Cation_ATPase_C PF00689.21 EJS42626.1 - 1.9 8.2 10.7 0.16 11.6 4.7 2.1 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus DUF3021 PF11457.8 EJS42626.1 - 7.2 7.0 16.7 0.51 10.7 8.9 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3021) CDC73_C PF05179.14 EJS42627.1 - 2.5e-56 189.7 2.0 3.7e-56 189.2 2.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Ntox46 PF15538.6 EJS42627.1 - 0.018 15.0 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 46 OB_NTP_bind PF07717.16 EJS42628.1 - 5.9e-18 65.0 0.0 1.5e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EJS42628.1 - 9.8e-16 58.1 0.1 4e-15 56.1 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 EJS42628.1 - 4.1e-11 43.2 1.0 2.1e-10 40.9 1.0 2.3 1 1 0 1 1 1 1 RWD domain DEAD PF00270.29 EJS42628.1 - 5.5e-10 39.3 1.1 1.3e-09 38.0 0.9 1.8 2 0 0 2 2 1 1 DEAD/DEAH box helicase HA2 PF04408.23 EJS42628.1 - 1.4e-07 31.7 0.1 1e-06 29.0 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) AAA_19 PF13245.6 EJS42628.1 - 0.00012 22.4 0.4 0.00036 20.9 0.4 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EJS42628.1 - 0.00029 20.4 1.4 0.00091 18.7 1.4 1.8 1 1 0 1 1 1 1 PhoH-like protein AAA_23 PF13476.6 EJS42628.1 - 0.0013 19.3 0.1 0.0013 19.3 0.1 4.0 2 1 1 3 3 2 1 AAA domain AAA_29 PF13555.6 EJS42628.1 - 0.0025 17.5 0.0 0.0077 16.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EJS42628.1 - 0.0029 17.9 1.2 0.027 14.7 0.7 2.8 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EJS42628.1 - 0.0032 16.6 0.0 0.0087 15.1 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EJS42628.1 - 0.0047 16.7 0.1 0.0093 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EJS42628.1 - 0.0082 15.7 0.0 0.019 14.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EJS42628.1 - 0.0087 16.0 0.6 0.041 13.8 0.1 2.4 2 0 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.18 EJS42628.1 - 0.016 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EJS42628.1 - 0.055 13.0 0.0 0.19 11.2 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EJS42628.1 - 0.064 12.6 0.1 0.064 12.6 0.1 2.7 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.27 EJS42628.1 - 0.15 12.6 0.8 0.78 10.3 0.0 2.7 2 1 0 2 2 2 0 ABC transporter APG17 PF04108.12 EJS42629.1 - 2e-84 284.0 18.8 2.3e-84 283.8 18.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Lip_prot_lig_C PF10437.9 EJS42629.1 - 0.0084 16.1 0.1 0.05 13.6 0.1 2.5 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus FTO_CTD PF12934.7 EJS42629.1 - 0.13 12.1 2.7 0.48 10.2 0.1 2.6 2 1 0 2 2 2 0 FTO C-terminal domain DUF948 PF06103.11 EJS42629.1 - 0.25 11.6 21.5 2.4 8.5 0.6 5.8 4 1 2 6 6 6 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 EJS42629.1 - 0.9 9.8 3.6 60 4.0 0.1 4.4 4 1 1 5 5 5 0 Proteins of 100 residues with WXG DUF3970 PF13113.6 EJS42629.1 - 1 9.6 4.0 4 7.7 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3970) PhageMin_Tail PF10145.9 EJS42629.1 - 3.1 7.6 4.3 26 4.6 0.1 3.0 3 1 0 3 3 3 0 Phage-related minor tail protein KxDL PF10241.9 EJS42629.1 - 4.2 7.7 16.2 0.45 10.8 1.1 4.7 3 2 1 4 4 4 0 Uncharacterized conserved protein PMC2NT PF08066.12 EJS42629.1 - 4.7 8.0 9.1 5.2 7.8 2.3 3.4 2 1 1 3 3 3 0 PMC2NT (NUC016) domain DUF1899 PF08953.11 EJS42630.1 - 6e-32 109.3 0.4 1.2e-31 108.4 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EJS42630.1 - 1.3e-19 69.7 1.0 3.3e-19 68.5 0.6 1.9 2 0 0 2 2 2 1 Type of WD40 repeat WD40 PF00400.32 EJS42630.1 - 9.2e-16 58.0 6.0 0.00048 20.9 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 EJS42630.1 - 3.3e-06 26.1 0.1 0.00022 20.0 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EJS42630.1 - 2.4e-05 24.3 0.1 0.023 14.6 0.0 2.6 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EJS42630.1 - 2.8e-05 24.3 0.3 0.084 13.2 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJS42630.1 - 0.041 12.8 0.0 1 8.2 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3759 PF12585.8 EJS42630.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3759) Ribosomal_L29 PF00831.23 EJS42631.1 - 1.7 8.7 7.5 9.2 6.3 0.4 4.2 4 0 0 4 4 4 0 Ribosomal L29 protein zf-RING_9 PF13901.6 EJS42631.1 - 2.3 8.1 6.3 1.1 9.2 0.6 2.9 2 2 1 3 3 3 0 Putative zinc-RING and/or ribbon DUF760 PF05542.11 EJS42631.1 - 2.6 8.5 8.5 4.4 7.7 3.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF760) DUF1664 PF07889.12 EJS42631.1 - 4 7.5 17.9 1.4 8.9 4.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) IMPDH PF00478.25 EJS42632.1 - 6e-133 443.1 2.6 7.3e-133 442.8 2.6 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EJS42632.1 - 2.8e-15 56.5 0.0 7.5e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EJS42632.1 - 1.2e-06 27.8 1.7 2.5e-06 26.7 1.7 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EJS42632.1 - 1.2e-05 24.8 6.0 0.0087 15.5 4.1 2.9 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 EJS42632.1 - 0.0002 20.9 0.8 0.0081 15.6 0.8 2.4 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EJS42632.1 - 0.11 11.7 1.6 0.12 11.6 0.3 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG WGG PF10273.9 EJS42633.1 - 4.9e-28 97.6 0.9 4.9e-28 97.6 0.9 2.1 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 DUF2457 PF10446.9 EJS42633.1 - 0.0015 17.8 13.3 0.002 17.3 13.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Vfa1 PF08432.10 EJS42633.1 - 0.0054 17.1 1.4 0.0054 17.1 1.4 1.4 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 R3H-assoc PF13902.6 EJS42633.1 - 0.047 14.1 0.1 0.11 12.9 0.1 1.6 1 1 0 1 1 1 0 R3H-associated N-terminal domain PBP1_TM PF14812.6 EJS42633.1 - 0.19 12.1 13.8 0.47 10.9 13.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 EJS42633.1 - 0.31 9.3 5.9 0.31 9.3 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 EJS42633.1 - 0.44 10.2 11.2 0.74 9.5 11.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 EJS42633.1 - 0.49 10.4 7.4 0.88 9.6 7.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.11 EJS42633.1 - 1.3 7.5 7.0 1.6 7.2 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 EJS42633.1 - 1.3 8.6 6.5 2.9 7.6 6.5 1.5 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EJS42633.1 - 1.4 8.2 15.8 1.9 7.7 15.8 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EJS42633.1 - 1.4 9.1 15.3 2 8.6 15.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 EJS42633.1 - 2.3 7.6 12.0 3.4 7.0 12.0 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EJS42633.1 - 5.3 5.0 16.4 7.4 4.5 16.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 EJS42634.1 - 3.3e-31 108.3 47.9 2.1e-18 65.9 13.9 4.5 2 2 0 2 2 2 2 High-temperature-induced dauer-formation protein Aminotran_3 PF00202.21 EJS42635.1 - 4.8e-124 414.1 0.0 5.5e-124 413.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EJS42635.1 - 0.0012 18.2 0.0 0.0035 16.7 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EJS42635.1 - 0.094 11.9 0.0 0.17 11.1 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class I and II LSM PF01423.22 EJS42636.1 - 1.6e-20 72.6 0.2 1.8e-20 72.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EJS42636.1 - 0.082 13.1 0.0 0.32 11.2 0.0 1.8 1 1 1 2 2 2 0 RimP C-terminal SH3 domain SH3_9 PF14604.6 EJS42636.1 - 0.15 11.9 0.2 3.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain MRP-L47 PF06984.13 EJS42637.1 - 1.1e-26 92.8 0.8 3.1e-26 91.3 0.2 2.1 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Sec39 PF08314.11 EJS42638.1 - 2.6e-128 429.6 16.6 9.4e-127 424.5 16.6 2.0 1 1 0 1 1 1 1 Secretory pathway protein Sec39 Ribosomal_S3Ae PF01015.18 EJS42639.1 - 3.3e-86 288.0 5.2 3.8e-86 287.8 5.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 EJS42639.1 - 0.048 13.2 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region SpoVIF PF14069.6 EJS42639.1 - 0.48 10.2 4.6 4.1 7.3 1.3 2.6 2 0 0 2 2 2 0 Stage VI sporulation protein F AAA_lid_10 PF17872.1 EJS42640.1 - 3.5e-39 132.9 6.1 7.7e-39 131.8 3.8 2.6 2 0 0 2 2 2 1 AAA lid domain BAH PF01426.18 EJS42640.1 - 4.6e-18 65.2 0.5 1.1e-17 64.0 0.5 1.7 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.6 EJS42640.1 - 0.035 14.4 0.5 0.27 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain SUR7 PF06687.12 EJS42641.1 - 1.4e-10 41.2 8.3 1.9e-10 40.7 8.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family Orf78 PF06024.12 EJS42641.1 - 0.07 13.4 0.4 0.22 11.9 0.4 1.8 1 0 0 1 1 1 0 Orf78 (ac78) vATP-synt_AC39 PF01992.16 EJS42642.1 - 4.9e-110 368.2 1.9 5.5e-110 368.0 1.9 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit FKBP_C PF00254.28 EJS42643.1 - 5.9e-28 97.0 0.1 2.4e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EJS42643.1 - 6.9e-24 84.4 0.6 6.9e-24 84.4 0.6 3.0 2 2 0 2 2 2 1 Nucleoplasmin-like domain SDA1 PF05285.12 EJS42643.1 - 7.1 6.0 63.7 1.4 8.3 44.2 2.1 2 0 0 2 2 2 0 SDA1 Zn_clus PF00172.18 EJS42644.1 - 2.5e-08 33.9 11.1 4.6e-08 33.1 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BSP_II PF05432.11 EJS42644.1 - 0.0054 16.5 8.5 0.01 15.6 8.5 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Sigma70_ner PF04546.13 EJS42644.1 - 0.0088 15.9 5.9 0.0088 15.9 5.9 1.9 2 0 0 2 2 2 1 Sigma-70, non-essential region CDC45 PF02724.14 EJS42644.1 - 0.015 13.7 2.2 0.027 12.8 2.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Radial_spoke PF04712.12 EJS42644.1 - 0.044 12.7 8.2 0.1 11.5 8.2 1.5 1 0 0 1 1 1 0 Radial spokehead-like protein BTD PF09270.10 EJS42644.1 - 0.044 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain FAM176 PF14851.6 EJS42644.1 - 0.1 12.2 6.5 0.32 10.6 6.5 1.8 1 0 0 1 1 1 0 FAM176 family DNA_PPF PF02916.15 EJS42644.1 - 0.16 12.4 1.4 1.9 8.9 0.2 2.9 3 0 0 3 3 3 0 DNA polymerase processivity factor DNA_pol_phi PF04931.13 EJS42644.1 - 1.3 7.0 10.5 2.5 6.1 10.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 EJS42644.1 - 1.5 8.8 10.6 1.3 9.1 4.5 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal MPP6 PF10175.9 EJS42644.1 - 1.5 9.3 9.2 1.3 9.6 3.2 2.5 2 0 0 2 2 2 0 M-phase phosphoprotein 6 PBP1_TM PF14812.6 EJS42644.1 - 2.9 8.3 5.2 7.3 7.0 5.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 EJS42644.1 - 7.7 7.0 11.5 16 5.9 11.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RGS PF00615.19 EJS42645.1 - 9.8e-19 67.8 0.4 5.6e-12 46.0 0.0 2.6 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.21 EJS42645.1 - 2.5e-13 49.9 0.0 2.1e-11 43.7 0.0 2.6 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TLD PF07534.16 EJS42645.1 - 0.024 14.8 3.0 0.29 11.4 0.4 2.7 2 0 0 2 2 2 0 TLD DUF1902 PF08972.11 EJS42645.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Peptidase_M16 PF00675.20 EJS42646.1 - 2.6e-52 176.7 0.0 4.9e-52 175.9 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EJS42646.1 - 5.8e-37 127.5 0.0 6.5e-36 124.1 0.0 2.4 2 1 1 3 3 3 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 EJS42646.1 - 0.043 12.9 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase M16C associated Sec10 PF07393.11 EJS42647.1 - 3.4e-207 690.2 34.3 4.4e-207 689.8 34.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 RTBV_P12 PF06361.11 EJS42647.1 - 0.032 14.6 0.5 0.032 14.6 0.5 2.9 2 1 1 3 3 3 0 Rice tungro bacilliform virus P12 protein ubiquitin PF00240.23 EJS42648.1 - 4.5e-34 116.0 0.6 7.7e-34 115.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EJS42648.1 - 1.6e-24 85.8 2.3 3.9e-24 84.6 2.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EJS42648.1 - 2.3e-16 59.4 0.9 4.7e-16 58.4 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EJS42648.1 - 2.4e-05 24.7 0.1 0.00012 22.4 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EJS42648.1 - 0.0014 18.7 0.4 0.0031 17.6 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EJS42648.1 - 0.0036 17.6 0.3 0.0076 16.6 0.1 1.6 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EJS42648.1 - 0.0052 16.7 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EJS42648.1 - 0.016 15.8 0.5 0.021 15.4 0.5 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EJS42648.1 - 0.02 15.0 1.0 5.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 EJS42648.1 - 0.02 15.1 0.2 0.037 14.3 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Fer2_3 PF13085.6 EJS42648.1 - 0.087 12.8 0.2 0.15 12.1 0.2 1.5 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain PRELI PF04707.14 EJS42649.1 - 3.4e-61 205.7 0.4 4.7e-61 205.2 0.4 1.2 1 0 0 1 1 1 1 PRELI-like family DUF3081 PF11280.8 EJS42649.1 - 0.056 13.3 0.1 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Clat_adaptor_s PF01217.20 EJS42650.1 - 1.7e-58 196.6 1.7 1.9e-58 196.4 1.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.20 EJS42651.1 - 1.2e-25 90.8 0.0 1.7e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.6 EJS42651.1 - 0.13 12.3 0.1 0.32 11.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) Iso_dh PF00180.20 EJS42653.1 - 2.4e-71 240.7 0.0 2.8e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YfmQ PF10787.9 EJS42653.1 - 0.027 14.2 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group DKCLD PF08068.12 EJS42654.1 - 1.8e-32 111.1 0.2 2e-31 107.8 0.3 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EJS42654.1 - 4e-23 81.3 0.3 8.6e-23 80.3 0.3 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EJS42654.1 - 2e-20 73.6 6.4 3.5e-19 69.6 0.1 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EJS42654.1 - 3.2e-19 68.7 1.0 6.3e-19 67.7 1.0 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EJS42654.1 - 0.029 14.6 0.0 0.078 13.2 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain GAGA_bind PF06217.12 EJS42654.1 - 0.54 10.5 21.7 0.76 10.0 21.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4746 PF15928.5 EJS42654.1 - 5 6.5 30.7 7.7 5.8 30.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PBP PF01161.20 EJS42655.1 - 3.3e-22 79.2 0.1 3.9e-22 79.0 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.20 EJS42656.1 - 8.2e-18 65.0 0.0 9.8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein S-AdoMet_synt_C PF02773.16 EJS42657.1 - 6.2e-65 217.4 0.0 1.1e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 EJS42657.1 - 1.6e-45 153.8 1.0 2.3e-45 153.3 0.2 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 EJS42657.1 - 2.4e-45 153.6 0.0 4.8e-45 152.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 EJS42657.1 - 0.036 12.8 0.4 0.16 10.7 0.2 1.9 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Swi6_N PF18530.1 EJS42658.1 - 3.1e-38 130.2 0.3 3.1e-38 130.2 0.3 3.3 3 0 0 3 3 2 1 Swi6 N-terminal domain Ank_2 PF12796.7 EJS42658.1 - 3.6e-10 40.3 1.5 0.002 18.7 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJS42658.1 - 2.9e-09 36.4 1.5 0.0004 20.6 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EJS42658.1 - 1.8e-08 34.5 1.8 0.0063 16.9 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EJS42658.1 - 4.4e-06 27.1 2.0 0.011 16.3 0.5 4.0 3 1 1 4 4 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJS42658.1 - 5.7e-06 26.5 14.1 1.5e-05 25.1 0.1 3.5 3 0 0 3 3 2 2 Ankyrin repeats (many copies) ATP-cone PF03477.16 EJS42658.1 - 0.001 19.6 0.7 1.4 9.5 0.1 2.8 2 0 0 2 2 2 2 ATP cone domain Phage_GPO PF05929.11 EJS42658.1 - 0.0037 16.9 5.4 0.0094 15.6 5.4 1.6 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase FAP206 PF12018.8 EJS42658.1 - 0.015 14.8 8.0 0.028 13.9 4.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF3287 PF11690.8 EJS42658.1 - 0.038 13.7 0.1 0.089 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) IMS PF00817.20 EJS42658.1 - 0.064 13.2 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 impB/mucB/samB family DUF2935 PF11155.8 EJS42658.1 - 0.39 11.1 4.0 1.2 9.5 4.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) TMPIT PF07851.13 EJS42658.1 - 2.4 7.3 6.9 5.8 6.1 6.9 1.6 1 0 0 1 1 1 0 TMPIT-like protein Med9 PF07544.13 EJS42658.1 - 2.7 8.1 10.0 1.7 8.8 5.4 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 betaPIX_CC PF16523.5 EJS42658.1 - 3.4 7.6 10.0 5.3 6.9 2.2 2.8 2 1 0 2 2 2 0 betaPIX coiled coil EMG1 PF03587.14 EJS42659.1 - 4.1e-78 261.5 0.0 4.9e-78 261.2 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PH PF00169.29 EJS42660.1 - 3.5e-06 27.5 0.3 6e-05 23.5 0.0 2.7 2 0 0 2 2 2 1 PH domain PPV_E1_N PF00524.18 EJS42660.1 - 0.034 14.6 0.1 0.034 14.6 0.1 2.6 3 0 0 3 3 3 0 E1 Protein, N terminal domain ABC_membrane PF00664.23 EJS42661.1 - 8e-64 215.9 5.3 1e-63 215.5 5.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EJS42661.1 - 4.1e-30 105.1 0.0 1.3e-29 103.5 0.0 1.9 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 EJS42661.1 - 2.5e-06 27.1 0.4 0.00024 20.6 0.4 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EJS42661.1 - 0.00097 19.4 0.1 0.015 15.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJS42661.1 - 0.001 19.5 0.1 0.005 17.2 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EJS42661.1 - 0.0022 18.4 0.0 0.031 14.7 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EJS42661.1 - 0.0051 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EJS42661.1 - 0.015 15.1 0.0 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_21 PF13304.6 EJS42661.1 - 0.015 15.2 0.6 0.26 11.1 0.1 2.7 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 EJS42661.1 - 0.022 14.8 0.1 0.3 11.1 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EJS42661.1 - 0.047 13.9 0.0 0.29 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EJS42661.1 - 0.055 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EJS42661.1 - 0.056 13.4 0.0 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EJS42661.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EJS42661.1 - 0.067 13.7 0.0 0.82 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EJS42661.1 - 0.079 12.7 0.0 0.38 10.5 0.0 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase Phage_int_SAM_1 PF02899.17 EJS42661.1 - 0.11 12.9 0.2 0.4 11.0 0.2 2.0 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain SbcCD_C PF13558.6 EJS42661.1 - 0.11 12.7 0.7 1.2 9.4 0.7 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Glyco_transf_28 PF03033.20 EJS42662.1 - 3.1e-37 127.7 0.0 7.2e-37 126.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 EJS42662.1 - 2.1e-27 95.3 8.7 1.6e-24 86.0 0.4 3.8 3 1 0 3 3 3 2 GRAM domain UDPGT PF00201.18 EJS42662.1 - 7.1e-10 38.3 0.0 1.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 EJS42662.1 - 8.4e-10 39.1 1.3 7.9e-09 36.0 0.8 2.8 2 0 0 2 2 2 1 PH domain Glyco_transf_4 PF13439.6 EJS42662.1 - 0.2 11.6 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EJS42662.1 - 0.26 11.7 0.0 0.73 10.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain PH_11 PF15413.6 EJS42662.1 - 0.48 10.9 7.5 0.064 13.7 0.5 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain MMR1 PF08505.10 EJS42663.1 - 1.3e-71 242.0 11.3 1.3e-71 242.0 11.3 2.4 2 0 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein Myb_DNA-bind_4 PF13837.6 EJS42663.1 - 0.1 13.0 1.6 0.71 10.3 0.4 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Med9 PF07544.13 EJS42663.1 - 0.11 12.6 0.3 0.11 12.6 0.3 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Allexi_40kDa PF05549.11 EJS42663.1 - 2.6 7.5 12.0 5.8 6.4 2.6 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein eIF3_subunit PF08597.10 EJS42664.1 - 8.2e-52 176.5 19.4 1.8e-51 175.4 19.4 1.5 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit PRELI PF04707.14 EJS42665.1 - 2e-50 170.7 0.2 2.4e-50 170.4 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family NMT_C PF02799.15 EJS42667.1 - 4.5e-80 268.1 0.8 7.5e-80 267.4 0.8 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EJS42667.1 - 1.1e-74 249.6 0.1 2.1e-74 248.7 0.1 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EJS42667.1 - 9.1e-07 29.0 0.0 0.0003 20.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EJS42667.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family WD40 PF00400.32 EJS42668.1 - 7.5e-07 29.8 7.9 0.0075 17.1 0.7 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.8 EJS42668.1 - 3.8e-05 22.5 2.7 0.00046 19.0 2.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 SUKH_6 PF14568.6 EJS42668.1 - 0.008 16.6 2.4 0.023 15.1 0.0 2.9 3 1 0 3 3 3 1 SMI1-KNR4 cell-wall WD40_like PF17005.5 EJS42668.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain ANAPC4_WD40 PF12894.7 EJS42668.1 - 0.13 12.5 0.9 7.9 6.9 0.2 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EJS42668.1 - 0.14 12.6 0.8 1.6 9.3 0.0 3.1 5 0 0 5 5 5 0 PQQ-like domain Nop PF01798.18 EJS42669.1 - 7.1e-85 284.1 0.1 7.1e-85 284.1 0.1 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EJS42669.1 - 3e-20 72.4 0.4 3e-20 72.4 0.4 2.6 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.12 EJS42669.1 - 0.24 11.7 14.5 0.38 11.0 14.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.11 EJS42669.1 - 0.77 9.8 44.8 1.2 9.2 44.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 EJS42669.1 - 1.9 8.2 23.9 3.1 7.5 23.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EJS42669.1 - 5.3 5.7 12.0 6.5 5.4 12.0 1.2 1 0 0 1 1 1 0 Presenilin Prefoldin_2 PF01920.20 EJS42670.1 - 3.5e-25 88.0 11.6 3.8e-25 87.9 11.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit MIP-T3_C PF17749.1 EJS42670.1 - 0.0049 16.8 1.6 0.0049 16.8 1.6 1.9 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region DUF4201 PF13870.6 EJS42670.1 - 0.011 15.5 7.3 0.012 15.3 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Sec2p PF06428.11 EJS42670.1 - 0.065 13.2 9.1 0.093 12.7 0.6 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Bcr-Abl_Oligo PF09036.10 EJS42670.1 - 0.069 13.2 0.3 0.069 13.2 0.3 2.1 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF1192 PF06698.11 EJS42670.1 - 0.072 13.1 1.6 0.072 13.1 1.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) UPF0242 PF06785.11 EJS42670.1 - 0.095 12.8 10.1 0.11 12.5 10.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin PF02996.17 EJS42670.1 - 0.096 12.6 6.1 0.18 11.7 6.1 1.6 1 1 0 1 1 1 0 Prefoldin subunit NBP1 PF08537.10 EJS42670.1 - 0.14 11.5 5.1 0.15 11.4 5.1 1.0 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Spc24 PF08286.11 EJS42670.1 - 0.22 11.8 9.9 0.58 10.4 1.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Uso1_p115_C PF04871.13 EJS42670.1 - 0.24 11.8 10.6 0.28 11.6 2.1 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 EJS42670.1 - 0.3 11.5 10.3 0.088 13.3 2.2 2.0 1 1 1 2 2 2 0 Fez1 DUF641 PF04859.12 EJS42670.1 - 0.39 11.0 8.4 2.8 8.3 8.4 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 EJS42670.1 - 0.43 9.8 2.2 0.38 10.0 1.3 1.3 1 1 0 1 1 1 0 TMPIT-like protein DMPK_coil PF08826.10 EJS42670.1 - 0.47 10.6 10.9 0.47 10.6 2.5 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Jnk-SapK_ap_N PF09744.9 EJS42670.1 - 0.81 9.9 15.4 4.1 7.6 15.4 1.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 EJS42670.1 - 1.1 9.5 7.7 2.9 8.1 6.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 EJS42670.1 - 1.2 9.5 8.7 30 4.9 8.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) PEP-utilisers_N PF05524.13 EJS42670.1 - 2.1 8.6 5.7 5.8 7.1 0.4 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal NuA4 PF09340.10 EJS42670.1 - 2.7 7.9 7.3 2.5 8.0 0.9 2.3 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 FlaC_arch PF05377.11 EJS42670.1 - 6.8 7.2 10.1 0.54 10.7 1.1 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 EJS42670.1 - 7.9 7.0 16.7 80 3.8 16.7 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region COQ9 PF08511.11 EJS42671.1 - 3.7e-22 77.9 1.2 8.9e-22 76.7 0.4 1.9 2 0 0 2 2 2 1 COQ9 DUF1447 PF07288.11 EJS42671.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) zf-Mss51 PF13824.6 EJS42672.1 - 1.9e-16 59.9 1.0 3.8e-16 58.9 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.11 EJS42672.1 - 0.02 14.6 0.6 0.055 13.2 0.6 1.8 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain DUF1713 PF08213.11 EJS42673.1 - 3.2e-11 43.0 24.6 4.7e-11 42.4 24.6 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) IZUMO PF15005.6 EJS42673.1 - 0.023 15.2 0.3 0.029 14.9 0.3 1.1 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated FAM199X PF15814.5 EJS42673.1 - 0.058 12.4 1.7 0.066 12.3 1.7 1.1 1 0 0 1 1 1 0 Protein family FAM199X Heme_oxygenase PF01126.20 EJS42674.1 - 2.3e-11 43.9 0.3 8e-11 42.1 0.3 1.9 1 1 0 1 1 1 1 Heme oxygenase Sel1 PF08238.12 EJS42675.1 - 9.8e-21 73.7 5.5 0.00016 22.3 0.0 8.5 8 0 0 8 8 8 3 Sel1 repeat TPR_1 PF00515.28 EJS42675.1 - 2.5e-05 23.9 14.1 0.36 10.7 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EJS42675.1 - 8.7e-05 22.9 2.3 6.3 7.7 0.3 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJS42675.1 - 0.0001 22.5 5.9 0.064 13.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJS42675.1 - 0.00018 21.4 14.5 0.22 11.7 1.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJS42675.1 - 0.0023 17.9 11.1 0.69 10.1 0.3 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EJS42675.1 - 0.0059 16.3 7.0 0.085 12.6 1.9 3.0 2 0 0 2 2 2 1 TPR repeat Lipoprotein_Ltp PF07553.11 EJS42675.1 - 0.03 14.6 0.1 0.14 12.4 0.1 2.2 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein SURF2 PF05477.11 EJS42675.1 - 0.052 13.2 1.4 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) TPR_8 PF13181.6 EJS42675.1 - 0.064 13.5 15.6 0.78 10.1 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EJS42675.1 - 0.33 10.9 4.4 47 4.0 0.3 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EJS42675.1 - 1.8 9.1 7.4 2.5 8.7 0.1 4.2 6 0 0 6 6 5 0 Tetratricopeptide repeat WD40 PF00400.32 EJS42676.1 - 3.2e-20 72.1 18.1 3.4e-05 24.5 0.6 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS42676.1 - 6.5e-07 29.6 5.4 0.1 12.9 0.1 4.6 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJS42676.1 - 0.018 14.0 0.3 7.1 5.5 0.0 3.8 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PNP_UDP_1 PF01048.20 EJS42677.1 - 2e-44 151.6 0.0 2.4e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Cyclin_N PF00134.23 EJS42678.1 - 2.8e-42 143.5 0.3 5.4e-42 142.5 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EJS42678.1 - 1.8e-29 102.3 0.1 5.8e-29 100.6 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Tubulin PF00091.25 EJS42679.1 - 9.4e-66 221.8 0.0 1.5e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EJS42679.1 - 2.2e-30 105.4 0.8 7.9e-30 103.6 0.4 2.0 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EJS42679.1 - 0.00016 22.0 0.0 0.00031 21.0 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EJS42679.1 - 0.0013 18.4 0.0 0.0045 16.7 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain Tubulin_2 PF13809.6 EJS42679.1 - 0.014 14.7 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Ferric_reduct PF01794.19 EJS42680.1 - 2e-25 89.3 9.2 2e-25 89.3 9.2 3.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EJS42680.1 - 2.2e-25 88.9 0.1 4.8e-25 87.8 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EJS42680.1 - 8.5e-22 78.0 0.0 1.7e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain CFEM PF05730.11 EJS42680.1 - 0.018 15.1 3.5 0.034 14.2 3.5 1.3 1 0 0 1 1 1 0 CFEM domain Pro_isomerase PF00160.21 EJS42681.1 - 3e-44 151.1 0.1 5.7e-44 150.2 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 EJS42681.1 - 1.7e-06 27.6 1.9 9e-06 25.3 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EJS42681.1 - 0.00027 20.8 2.8 0.0016 18.4 0.1 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EJS42681.1 - 0.16 12.7 3.1 0.41 11.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJS42681.1 - 0.51 10.7 0.1 0.51 10.7 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat VIT1 PF01988.19 EJS42682.1 - 2.9e-62 210.3 0.2 3.5e-62 210.1 0.2 1.1 1 0 0 1 1 1 1 VIT family T3RM_EcoP15I_C PF18273.1 EJS42682.1 - 0.053 13.8 0.1 0.095 13.0 0.1 1.4 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain CsgG PF03783.14 EJS42682.1 - 0.15 11.3 2.0 0.21 10.9 0.3 2.1 2 1 1 3 3 3 0 Curli production assembly/transport component CsgG Rsa3 PF14615.6 EJS42683.1 - 1.2e-17 63.1 0.1 2e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 SR-25 PF10500.9 EJS42683.1 - 0.087 12.4 18.6 0.12 11.9 18.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 EJS42683.1 - 0.13 10.3 19.0 0.15 10.1 19.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IMUP PF15761.5 EJS42683.1 - 0.9 10.3 15.7 0.93 10.2 14.7 1.5 1 1 0 1 1 1 0 Immortalisation up-regulated protein DUF3827 PF12877.7 EJS42683.1 - 3.3 6.0 15.2 4.3 5.6 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) AC_N PF16214.5 EJS42683.1 - 9.2 5.3 7.3 11 5.0 7.3 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Utp13 PF08625.11 EJS42684.1 - 4.9e-50 169.1 1.6 8.4e-50 168.4 1.6 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 EJS42684.1 - 3.3e-44 148.0 14.4 2.7e-06 28.0 0.0 10.8 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS42684.1 - 1.8e-21 76.2 4.5 0.0007 19.8 0.1 7.4 5 2 3 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EJS42684.1 - 1.6e-06 27.6 8.5 0.015 14.6 0.1 4.7 3 2 2 5 5 5 3 WD40-like domain Nup160 PF11715.8 EJS42684.1 - 7.6e-06 24.8 8.0 1.2 7.7 0.4 5.9 2 2 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EJS42684.1 - 5e-05 22.2 1.6 0.33 9.6 0.2 3.2 1 1 1 3 3 3 2 Nup133 N terminal like Svf1_C PF17187.4 EJS42686.1 - 2e-39 135.0 0.9 9.4e-39 132.9 0.9 2.0 1 1 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EJS42686.1 - 2.6e-39 134.9 0.0 4.6e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain FAD_binding_6 PF00970.24 EJS42686.1 - 0.049 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Ras PF00071.22 EJS42688.1 - 7.6e-51 171.9 0.0 8.8e-51 171.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS42688.1 - 1.8e-18 66.9 0.0 2.5e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS42688.1 - 7.2e-07 28.8 0.0 9.6e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.5 EJS42688.1 - 0.16 12.2 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Aminotran_5 PF00266.19 EJS42689.1 - 2.1e-13 50.0 0.0 4.8e-13 48.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Topoisom_bac PF01131.20 EJS42690.1 - 8.9e-100 334.6 0.0 1.5e-99 333.8 0.0 1.4 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 EJS42690.1 - 1.8e-22 79.5 0.0 5.6e-22 77.9 0.0 1.9 2 0 0 2 2 2 1 Toprim domain FHA PF00498.26 EJS42691.1 - 1.4e-18 67.0 1.0 5.4e-17 61.9 0.4 3.0 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EJS42691.1 - 1.7e-05 25.0 0.0 8.9e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Exonuc_VII_L PF02601.15 EJS42691.1 - 0.23 11.0 7.4 0.4 10.2 7.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit BPL_LplA_LipB PF03099.19 EJS42692.1 - 2.9e-26 91.9 0.1 4.4e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PI3Ka PF00613.20 EJS42693.1 - 3e-77 258.2 3.5 4.8e-77 257.5 3.5 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EJS42693.1 - 2.5e-52 178.2 0.1 3.2e-49 168.0 0.0 3.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EJS42693.1 - 2.5e-31 108.5 0.8 7.2e-31 107.0 0.4 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 TFA2_Winged_2 PF18121.1 EJS42693.1 - 0.079 12.7 0.3 0.22 11.2 0.3 1.8 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 AlcCBM31 PF11606.8 EJS42693.1 - 0.13 12.4 0.0 0.47 10.7 0.0 1.9 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein RSN1_7TM PF02714.15 EJS42694.1 - 2.4e-82 276.3 25.9 5.5e-82 275.1 25.9 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EJS42694.1 - 2.7e-44 150.7 1.7 2.7e-44 150.7 1.7 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EJS42694.1 - 4.1e-33 115.1 0.0 6e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Arv1 PF04161.13 EJS42695.1 - 6.4e-64 216.0 9.6 6.4e-64 216.0 9.6 1.4 2 0 0 2 2 2 1 Arv1-like family Prok-RING_4 PF14447.6 EJS42695.1 - 0.44 10.4 1.7 1.2 9.0 1.7 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 ATP_bind_1 PF03029.17 EJS42696.1 - 1.8e-89 299.6 0.0 2.1e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EJS42696.1 - 0.00044 19.3 0.1 0.001 18.1 0.0 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 EJS42696.1 - 0.0016 18.3 0.0 0.011 15.5 0.0 2.2 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 EJS42696.1 - 0.002 18.2 0.0 0.0054 16.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.7 EJS42696.1 - 0.0027 16.7 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.27 EJS42696.1 - 0.0027 18.2 0.0 0.0053 17.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter KAP_NTPase PF07693.14 EJS42696.1 - 0.0036 16.6 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_24 PF13479.6 EJS42696.1 - 0.0046 16.7 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EJS42696.1 - 0.0052 17.2 0.0 0.017 15.5 0.0 1.9 2 0 0 2 2 1 1 RNA helicase RsgA_GTPase PF03193.16 EJS42696.1 - 0.0057 16.6 0.2 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Fer4_NifH PF00142.18 EJS42696.1 - 0.0087 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 EJS42696.1 - 0.012 14.8 0.3 0.069 12.3 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 EJS42696.1 - 0.013 16.1 0.0 0.034 14.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EJS42696.1 - 0.022 14.8 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_7 PF12775.7 EJS42696.1 - 0.028 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EJS42696.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EJS42696.1 - 0.037 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_31 PF13614.6 EJS42696.1 - 0.037 13.9 0.0 1.2 9.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EJS42696.1 - 0.039 14.2 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EJS42696.1 - 0.041 13.6 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EJS42696.1 - 0.056 13.8 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EJS42696.1 - 0.062 12.8 0.1 0.49 9.9 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain NACHT PF05729.12 EJS42696.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 EJS42696.1 - 0.09 12.8 0.0 0.12 12.5 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TrwB_AAD_bind PF10412.9 EJS42696.1 - 0.099 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 EJS42696.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 EJS42696.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EJS42696.1 - 0.15 12.1 0.0 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 EJS42696.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EJS42696.1 - 0.24 11.6 0.0 0.41 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_M24 PF00557.24 EJS42697.1 - 3.4e-54 183.7 0.5 9.8e-54 182.2 0.0 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EJS42697.1 - 3.7e-15 56.0 6.1 3.7e-15 56.0 6.1 1.8 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding DHHC PF01529.20 EJS42698.1 - 1.2e-31 109.6 10.1 1.2e-31 109.6 10.1 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase SDF PF00375.18 EJS42698.1 - 0.0065 15.5 0.1 0.0065 15.5 0.1 2.1 3 0 0 3 3 3 1 Sodium:dicarboxylate symporter family DUF4149 PF13664.6 EJS42698.1 - 0.13 12.6 3.4 1.4 9.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Pro_dh PF01619.18 EJS42700.1 - 1.2e-61 208.8 0.0 1.5e-61 208.5 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Diphthami_syn_2 PF01902.17 EJS42701.1 - 1.4e-35 122.8 0.0 1.7e-34 119.2 0.0 2.5 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EJS42701.1 - 2e-17 63.3 0.0 4.4e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP Dabb PF07876.12 EJS42701.1 - 0.02 15.5 0.1 2.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Stress responsive A/B Barrel Domain Glyco_hydro81C PF17652.1 EJS42702.1 - 1.3e-148 494.9 7.4 2.1e-148 494.2 7.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EJS42702.1 - 1.7e-93 313.3 0.1 2.7e-93 312.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain HisKA_7TM PF16927.5 EJS42702.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase Spermine_synth PF01564.17 EJS42704.1 - 2.2e-71 239.2 0.0 5.6e-71 237.8 0.0 1.6 1 1 1 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EJS42704.1 - 2.4e-24 85.0 0.1 4.6e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_23 PF13489.6 EJS42704.1 - 0.00014 21.8 0.0 0.00045 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJS42704.1 - 0.0003 20.6 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJS42704.1 - 0.0018 19.0 0.0 0.004 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EJS42704.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_25 PF13649.6 EJS42704.1 - 0.097 13.4 0.0 0.24 12.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Pep3_Vps18 PF05131.14 EJS42705.1 - 3.9e-42 143.6 0.4 1.2e-41 142.0 0.4 1.9 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EJS42705.1 - 1.1e-17 64.2 5.8 1.1e-17 64.2 5.8 4.1 5 0 0 5 5 5 2 Region in Clathrin and VPS Vps39_2 PF10367.9 EJS42705.1 - 2.6e-05 24.6 3.4 4e-05 24.0 0.3 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 EJS42705.1 - 0.0041 16.8 2.5 0.0099 15.6 2.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EJS42705.1 - 0.0051 16.8 1.9 0.013 15.5 1.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EJS42705.1 - 0.0059 16.9 3.7 0.0059 16.9 3.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EJS42705.1 - 0.019 14.9 5.5 0.039 13.9 5.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EJS42705.1 - 0.068 13.0 2.6 0.17 11.8 2.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNHCP PF12647.7 EJS42705.1 - 0.16 12.0 1.1 0.32 11.0 1.1 1.4 1 0 0 1 1 1 0 RNHCP domain zf-C3HC4 PF00097.25 EJS42705.1 - 0.48 10.3 2.3 1.2 9.0 2.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2415 PF10313.9 EJS42706.1 - 4.6e-21 74.5 1.1 9.6e-21 73.4 1.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Str_synth PF03088.16 EJS42706.1 - 0.049 13.7 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Strictosidine synthase POLO_box PF00659.18 EJS42706.1 - 0.098 12.9 4.7 5.7 7.2 0.1 3.7 3 0 0 3 3 3 0 POLO box duplicated region Stm1_N PF09598.10 EJS42707.1 - 8.5e-08 32.9 4.7 8.5e-08 32.9 4.7 4.1 1 1 1 3 3 3 1 Stm1 UPF0225 PF17775.1 EJS42707.1 - 0.46 11.3 5.6 0.14 13.0 2.1 1.9 1 1 1 2 2 2 0 UPF0225 domain Mem_trans PF03547.18 EJS42708.1 - 1.5e-27 96.0 6.6 1e-17 63.6 2.4 2.1 2 0 0 2 2 2 2 Membrane transport protein TcpE PF12648.7 EJS42708.1 - 0.047 14.2 0.0 0.047 14.2 0.0 3.9 3 2 1 4 4 4 0 TcpE family AMP-binding PF00501.28 EJS42709.1 - 1.9e-83 280.4 0.1 2.6e-83 280.0 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJS42709.1 - 4.1e-23 82.2 0.0 9.9e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EJS42709.1 - 5.7e-21 74.2 0.8 1.4e-20 72.9 0.8 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus BTB_2 PF02214.22 EJS42711.1 - 5e-07 30.0 2.4 0.005 17.2 0.1 2.9 2 1 0 2 2 2 2 BTB/POZ domain Redoxin PF08534.10 EJS42712.1 - 4.1e-32 110.9 0.2 4.4e-32 110.8 0.2 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EJS42712.1 - 4.2e-06 26.7 0.0 5.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Alkyl_sulf_C PF14864.6 EJS42712.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Flocculin_t3 PF13928.6 EJS42713.1 - 1.3e-15 57.6 18.9 1.3e-15 57.6 18.9 3.2 3 0 0 3 3 3 1 Flocculin type 3 repeat MF_alpha_N PF05436.11 EJS42713.1 - 4.6 7.2 7.2 7.9 6.5 1.8 2.4 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus Pkinase PF00069.25 EJS42714.1 - 7.4e-67 225.5 0.0 1.2e-66 224.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42714.1 - 6.9e-31 107.5 0.0 9.8e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJS42714.1 - 2.3e-06 26.8 0.1 3e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EJS42714.1 - 7.1e-05 22.2 0.2 0.00025 20.5 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJS42714.1 - 0.00087 19.3 0.8 0.0022 17.9 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 EJS42714.1 - 0.033 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EJS42714.1 - 0.036 13.4 0.0 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 EJS42714.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Lactamase_B_6 PF16661.5 EJS42715.1 - 5.8e-79 264.0 0.0 1.2e-78 263.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EJS42715.1 - 5.6e-20 72.2 15.2 1.3e-19 71.0 0.5 3.8 3 2 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Rep_fac-A_3 PF08661.11 EJS42715.1 - 0.016 15.6 0.1 0.061 13.7 0.1 2.0 1 0 0 1 1 1 0 Replication factor A protein 3 HAT PF02184.16 EJS42716.1 - 2.8e-22 78.4 27.9 1.2e-08 34.7 0.1 8.8 8 0 0 8 8 8 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EJS42716.1 - 3.7e-18 64.7 0.2 0.033 15.0 0.0 8.1 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EJS42716.1 - 3.2e-08 34.0 0.0 0.039 14.5 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EJS42716.1 - 2.9e-06 27.3 0.8 0.0024 18.1 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Suf PF05843.14 EJS42716.1 - 6.1e-05 23.2 20.3 0.023 14.7 0.5 5.5 3 2 1 4 4 4 3 Suppressor of forked protein (Suf) U3_assoc_6 PF08640.11 EJS42716.1 - 0.02 14.9 21.2 0.036 14.1 2.1 6.2 4 2 2 6 6 6 0 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.17 EJS42716.1 - 0.07 13.3 19.8 1.7 9.0 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat Gal11_ABD1 PF18535.1 EJS42716.1 - 0.084 13.0 0.3 0.72 10.0 0.0 2.8 3 0 0 3 3 3 0 Gal11 activator-binding domain (ABD1) SNAP-25 PF00835.19 EJS42716.1 - 0.12 12.6 0.0 0.4 11.0 0.0 1.9 1 0 0 1 1 1 0 SNAP-25 family TPR_8 PF13181.6 EJS42716.1 - 1.7 9.0 14.5 27 5.3 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat GATase PF00117.28 EJS42717.1 - 2e-14 53.8 0.1 2.4e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EJS42717.1 - 0.0095 15.7 0.1 0.058 13.1 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 STb_secrete PF09075.10 EJS42717.1 - 0.026 14.6 0.1 0.054 13.6 0.1 1.5 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory WD40 PF00400.32 EJS42718.1 - 3.1e-48 160.7 36.1 9e-07 29.5 0.2 10.7 10 0 0 10 10 10 10 WD domain, G-beta repeat Utp12 PF04003.12 EJS42718.1 - 9.5e-18 64.5 0.3 1.7e-17 63.6 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EJS42718.1 - 1.7e-17 63.4 6.8 0.0052 17.1 0.0 8.0 2 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJS42718.1 - 1.6e-09 37.0 4.8 0.017 13.8 0.0 5.0 4 1 0 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EJS42718.1 - 2e-09 37.2 4.5 0.00056 19.3 0.1 4.7 4 1 1 5 5 5 2 WD40-like domain Hira PF07569.11 EJS42718.1 - 2.5e-06 27.4 2.8 1 9.0 0.0 5.2 5 0 0 5 5 5 3 TUP1-like enhancer of split eIF2A PF08662.11 EJS42718.1 - 0.0052 16.7 1.6 0.33 10.8 0.0 4.2 4 2 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EJS42718.1 - 0.0052 15.8 8.8 7.4 5.4 0.0 6.3 2 2 5 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 EJS42718.1 - 0.018 14.0 11.5 1.8 7.4 0.1 5.0 4 1 1 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Ets PF00178.22 EJS42718.1 - 0.1 13.1 0.2 0.49 10.9 0.2 2.2 1 0 0 1 1 1 0 Ets-domain ELYS-bb PF16687.5 EJS42718.1 - 0.13 10.8 0.0 4.9 5.7 0.0 2.4 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin tRNA_SAD PF07973.14 EJS42718.1 - 0.38 10.9 1.1 20 5.3 0.2 2.5 2 0 0 2 2 2 0 Threonyl and Alanyl tRNA synthetase second additional domain Zip PF02535.22 EJS42719.1 - 3.6e-86 289.4 1.9 4.3e-86 289.2 1.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.13 EJS42719.1 - 0.0075 15.9 3.5 0.0088 15.6 0.8 2.1 2 0 0 2 2 2 1 UNC-50 family Cation_ATPase_C PF00689.21 EJS42719.1 - 2.6 7.7 8.7 8.3 6.1 2.7 2.5 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus zf-C2H2 PF00096.26 EJS42720.1 - 7.9e-11 41.8 13.9 0.0002 21.6 0.9 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJS42720.1 - 1.5e-05 25.4 9.4 0.15 13.0 0.5 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EJS42720.1 - 0.01 15.8 2.0 4.7 7.3 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EJS42720.1 - 0.019 15.4 0.1 0.019 15.4 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain FOXP-CC PF16159.5 EJS42720.1 - 7.7 7.2 12.0 5.8 7.6 0.1 3.7 3 1 1 4 4 4 0 FOXP coiled-coil domain HVSL PF09749.9 EJS42721.1 - 1.4e-27 96.7 0.3 1.7e-27 96.4 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Choline_kinase PF01633.20 EJS42722.1 - 1.2e-70 237.4 0.2 1.6e-70 237.0 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EJS42722.1 - 1.9e-15 56.3 0.1 3.7e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EJS42722.1 - 8.9e-07 29.1 0.3 0.00018 21.5 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family TPP_enzyme_N PF02776.18 EJS42723.1 - 3.9e-32 111.2 0.0 6.3e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EJS42723.1 - 2.5e-29 101.8 0.0 1.4e-28 99.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EJS42723.1 - 1.7e-14 53.8 0.0 3.4e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF362 PF04015.12 EJS42723.1 - 0.003 17.8 0.0 0.0067 16.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF362) CO_dh PF02552.16 EJS42723.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit OCC1 PF15506.6 EJS42723.1 - 0.18 12.0 0.2 5.8 7.1 0.1 2.5 2 0 0 2 2 2 0 OCC1 family Slx4 PF09494.10 EJS42724.1 - 1.1e-14 54.1 0.6 3.3e-14 52.6 0.1 2.1 2 0 0 2 2 2 1 Slx4 endonuclease zf-CCCH PF00642.24 EJS42725.1 - 5.9e-16 57.9 17.9 1.8e-09 37.3 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EJS42725.1 - 6.9e-06 25.9 1.4 6.9e-06 25.9 1.4 3.0 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 EJS42725.1 - 0.00023 20.9 15.6 0.00051 19.8 0.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Defensin_int PF17858.1 EJS42725.1 - 0.00097 19.1 3.5 0.14 12.2 1.4 2.5 2 0 0 2 2 2 2 Platypus intermediate defensin-like peptide Torus PF16131.5 EJS42725.1 - 0.016 15.9 1.1 0.016 15.9 1.1 3.0 3 1 1 4 4 4 0 Torus domain Methyltransf_16 PF10294.9 EJS42726.1 - 1.2e-06 28.3 0.1 0.0043 16.8 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase PRIMA1 PF16101.5 EJS42726.1 - 0.022 14.8 6.7 0.046 13.8 6.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 EJS42726.1 - 0.031 14.4 2.6 0.05 13.7 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EJS42726.1 - 0.52 9.8 3.8 0.81 9.1 3.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Na_H_Exchanger PF00999.21 EJS42727.1 - 2.1e-90 303.3 26.1 2.6e-90 303.0 26.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 EJS42727.1 - 5.4e-82 276.5 46.7 1.7e-71 241.9 32.3 2.1 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus SLS PF14611.6 EJS42728.1 - 5e-32 111.5 0.2 1.1e-31 110.4 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator DUF4461 PF14688.6 EJS42728.1 - 0.029 14.1 0.5 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) DUF3437 PF11919.8 EJS42728.1 - 0.12 12.3 0.3 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Gaa1 PF04114.14 EJS42730.1 - 7.5e-132 440.9 9.7 9.6e-132 440.5 9.7 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PHO4 PF01384.20 EJS42730.1 - 0.38 9.7 3.1 0.81 8.7 3.1 1.5 1 0 0 1 1 1 0 Phosphate transporter family Aminotran_1_2 PF00155.21 EJS42731.1 - 5.2e-36 124.6 0.0 8.3e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EJS42731.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DnaJ_C PF01556.18 EJS42732.1 - 4.4e-27 95.0 0.0 6.2e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EJS42732.1 - 3.9e-24 84.6 2.9 6.9e-24 83.7 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EJS42732.1 - 6.2e-11 42.5 10.8 2.2e-10 40.7 11.0 1.8 1 1 1 2 2 2 2 DnaJ central domain NOB1_Zn_bind PF08772.11 EJS42732.1 - 0.0033 17.5 0.3 0.011 15.9 0.3 1.8 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Anti-TRAP PF15777.5 EJS42732.1 - 0.018 15.0 12.7 0.16 11.9 2.7 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 EJS42732.1 - 0.088 13.2 5.0 0.52 10.7 0.8 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar Cytochrome_C554 PF13435.6 EJS42732.1 - 0.27 12.2 5.1 0.85 10.6 0.3 3.1 3 0 0 3 3 3 0 Cytochrome c554 and c-prime DUF4460 PF14687.6 EJS42732.1 - 0.36 10.9 2.4 0.54 10.3 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4460) Stap_Strp_tox_C PF02876.17 EJS42732.1 - 0.41 11.0 6.3 0.48 10.7 2.6 2.5 1 1 1 2 2 2 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Cytochrom_c3_2 PF14537.6 EJS42732.1 - 1.4 9.4 7.4 2.2 8.8 3.4 2.5 1 1 1 2 2 2 0 Cytochrome c3 Sulfate_transp PF00916.20 EJS42733.1 - 1.8e-129 431.8 9.7 2.3e-129 431.5 9.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EJS42733.1 - 0.00017 21.2 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EJS42733.1 - 0.032 14.6 0.0 0.09 13.1 0.0 1.7 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 EJS42733.1 - 2.9 8.3 9.8 0.073 13.5 0.9 2.5 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily RPM2 PF08579.11 EJS42734.1 - 0.098 13.1 0.6 0.34 11.3 0.2 2.0 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) Pkinase PF00069.25 EJS42735.1 - 4.2e-68 229.6 3.0 4.1e-66 223.0 3.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42735.1 - 4.9e-39 134.2 0.5 5.7e-38 130.7 0.5 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EJS42735.1 - 3e-17 62.1 0.0 6e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 EJS42735.1 - 2.1e-06 27.3 0.0 3.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJS42735.1 - 0.0001 21.7 0.1 0.00024 20.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJS42735.1 - 0.0036 17.3 0.0 0.045 13.7 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EJS42735.1 - 0.011 14.5 0.0 0.011 14.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EJS42735.1 - 0.11 12.0 3.2 0.077 12.5 0.4 2.2 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Abhydrolase_1 PF00561.20 EJS42736.1 - 5.3e-22 78.7 0.0 4.3e-21 75.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJS42736.1 - 5.7e-13 50.0 0.0 8.7e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EJS42736.1 - 6.9e-11 41.9 0.0 6.6e-09 35.4 0.0 2.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 DUF915 PF06028.11 EJS42736.1 - 1.2e-07 31.3 0.1 0.0017 17.8 0.1 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 EJS42736.1 - 1.9e-05 23.5 0.0 0.0051 15.6 0.0 2.5 2 1 0 2 2 2 2 Ndr family Abhydrolase_3 PF07859.13 EJS42736.1 - 3.5e-05 23.8 0.0 0.059 13.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EJS42736.1 - 9.7e-05 22.0 0.0 0.00017 21.3 0.0 1.5 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase BAAT_C PF08840.11 EJS42736.1 - 0.00015 21.8 0.0 0.071 13.0 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 EJS42736.1 - 0.00061 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 EJS42736.1 - 0.0037 17.0 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 EJS42736.1 - 0.0059 15.5 0.0 0.018 13.9 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Thioesterase PF00975.20 EJS42736.1 - 0.0065 16.6 0.0 0.31 11.1 0.0 2.7 3 0 0 3 3 3 1 Thioesterase domain Palm_thioest PF02089.15 EJS42736.1 - 0.0099 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 EJS42736.1 - 0.013 15.0 0.1 6.1 6.3 0.0 2.6 3 0 0 3 3 3 0 Lipase (class 2) DUF676 PF05057.14 EJS42736.1 - 0.028 14.0 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DLH PF01738.18 EJS42736.1 - 0.044 13.3 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.25 EJS42736.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.11 EJS42736.1 - 0.057 12.4 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_5 PF12695.7 EJS42736.1 - 0.069 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.25 EJS42737.1 - 1.5e-12 47.4 0.1 1.8e-11 43.9 0.1 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJS42737.1 - 0.0065 16.0 0.0 0.13 11.8 0.0 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF948 PF06103.11 EJS42737.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CDC45 PF02724.14 EJS42738.1 - 3.6e-216 719.4 1.5 4.1e-216 719.2 1.5 1.0 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 EJS42738.1 - 0.0091 16.1 5.4 0.0091 16.1 5.4 1.9 2 0 0 2 2 2 1 YL1 nuclear protein Sigma70_ner PF04546.13 EJS42738.1 - 1.1 9.1 11.1 1.7 8.5 5.1 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF1840 PF08895.11 EJS42738.1 - 1.9 8.9 3.5 3.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) tRNA_int_endo PF01974.17 EJS42739.1 - 5.8e-22 77.6 0.6 1.2e-21 76.6 0.6 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain LRIF1 PF15741.5 EJS42739.1 - 0.062 11.8 4.1 0.083 11.4 4.1 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 AAA_5 PF07728.14 EJS42740.1 - 5.2e-122 402.3 0.1 1.1e-20 74.1 0.0 9.7 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EJS42740.1 - 1.8e-52 176.0 1.0 2e-19 69.7 0.0 5.1 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 EJS42740.1 - 1.3e-32 112.0 0.4 1.1e-29 102.6 0.0 4.5 4 0 0 4 4 2 1 Midasin AAA lid domain AAA_3 PF07726.11 EJS42740.1 - 1.8e-32 112.0 0.0 2.9e-10 40.1 0.0 8.3 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EJS42740.1 - 6.1e-29 100.8 9.5 1.6e-06 27.8 1.2 6.9 7 0 0 7 7 6 5 P-loop containing dynein motor region AAA PF00004.29 EJS42740.1 - 1.8e-26 93.1 2.8 0.00026 21.4 0.1 7.9 8 0 0 8 8 7 5 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 EJS42740.1 - 7.7e-24 84.2 1.6 0.0012 17.9 0.2 10.2 10 1 0 10 10 10 4 Hydrolytic ATP binding site of dynein motor region Dynein_heavy PF03028.15 EJS42740.1 - 2.8e-22 79.0 0.2 6.5e-06 26.2 0.0 9.0 9 1 1 10 10 7 3 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 EJS42740.1 - 1e-20 74.8 7.3 0.0039 17.6 0.7 8.8 7 2 0 8 8 7 5 AAA ATPase domain Sigma54_activat PF00158.26 EJS42740.1 - 5.8e-18 65.1 0.4 0.0025 17.6 0.0 5.8 5 0 0 5 5 5 4 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EJS42740.1 - 1.3e-17 64.2 0.2 0.00046 20.3 0.0 6.7 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_22 PF13401.6 EJS42740.1 - 3.4e-16 59.8 1.2 0.03 14.6 0.0 8.0 7 0 0 7 7 6 3 AAA domain TsaE PF02367.17 EJS42740.1 - 7.3e-16 58.3 3.5 0.032 14.2 0.1 6.7 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EJS42740.1 - 8.4e-16 58.3 0.1 0.043 13.5 0.0 7.4 9 0 0 9 9 6 3 AAA domain AAA_18 PF13238.6 EJS42740.1 - 9.3e-16 58.6 14.7 0.02 15.4 0.1 8.8 8 1 0 8 8 6 4 AAA domain AAA_14 PF13173.6 EJS42740.1 - 1.7e-13 50.7 8.6 0.0048 16.9 0.0 9.0 9 0 0 9 9 7 1 AAA domain RNA_helicase PF00910.22 EJS42740.1 - 5.6e-13 49.2 1.1 0.065 13.6 0.0 7.2 7 0 0 7 7 6 2 RNA helicase AAA_33 PF13671.6 EJS42740.1 - 1.4e-12 48.0 1.2 0.0015 18.7 0.2 6.8 6 0 0 6 6 6 1 AAA domain T2SSE PF00437.20 EJS42740.1 - 2.3e-12 46.6 6.3 0.0061 15.7 0.0 6.1 6 0 0 6 6 6 3 Type II/IV secretion system protein Rad17 PF03215.15 EJS42740.1 - 1.4e-11 44.6 2.9 0.61 10.0 0.1 7.1 6 0 0 6 6 6 2 Rad17 P-loop domain Zeta_toxin PF06414.12 EJS42740.1 - 7.5e-11 41.7 0.3 0.79 9.0 0.0 7.1 8 0 0 8 8 7 2 Zeta toxin AAA_19 PF13245.6 EJS42740.1 - 1.3e-10 41.8 0.4 0.22 11.9 0.0 6.8 6 0 0 6 6 6 1 AAA domain ABC_tran PF00005.27 EJS42740.1 - 2.4e-10 41.1 33.7 0.0003 21.3 0.0 7.9 8 1 1 9 9 6 4 ABC transporter RsgA_GTPase PF03193.16 EJS42740.1 - 4e-10 39.9 8.6 0.051 13.5 0.5 5.8 6 0 0 6 6 5 3 RsgA GTPase Mg_chelatase PF01078.21 EJS42740.1 - 4.2e-10 39.4 0.8 2.2 7.6 0.0 8.3 10 0 0 10 10 9 1 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 EJS42740.1 - 4.4e-09 36.2 5.1 0.029 14.1 0.1 5.8 6 0 0 6 6 5 2 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 EJS42740.1 - 7.3e-09 35.6 0.4 2.9 7.6 0.1 5.6 6 0 0 6 6 5 2 IstB-like ATP binding protein NACHT PF05729.12 EJS42740.1 - 2e-08 34.3 8.6 0.2 11.6 0.2 6.1 6 0 0 6 6 5 2 NACHT domain AAA_25 PF13481.6 EJS42740.1 - 2.3e-08 33.8 2.5 0.16 11.5 0.0 5.2 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 EJS42740.1 - 6.1e-08 32.3 2.1 2.9 7.7 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain RuvB_N PF05496.12 EJS42740.1 - 6.8e-08 32.4 2.4 0.089 12.5 0.0 5.6 6 0 0 6 6 5 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EJS42740.1 - 2.1e-07 31.3 6.7 6.7 6.9 0.4 6.6 6 0 0 6 6 6 0 AAA domain DUF815 PF05673.13 EJS42740.1 - 2.6e-07 30.0 1.1 0.13 11.4 0.1 5.2 5 0 0 5 5 5 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 EJS42740.1 - 3e-07 30.5 2.3 12 6.0 0.1 7.1 6 0 0 6 6 6 0 50S ribosome-binding GTPase TniB PF05621.11 EJS42740.1 - 4.4e-07 29.5 0.7 1.9 7.9 0.0 5.9 6 0 0 6 6 5 1 Bacterial TniB protein SRP54 PF00448.22 EJS42740.1 - 1e-06 28.5 7.4 0.17 11.5 0.6 5.6 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain KAP_NTPase PF07693.14 EJS42740.1 - 1.7e-06 27.5 2.6 0.065 12.5 0.0 5.6 5 0 0 5 5 5 1 KAP family P-loop domain Roc PF08477.13 EJS42740.1 - 8.1e-06 26.1 8.2 4.4 7.6 0.2 6.6 7 0 0 7 7 6 0 Ras of Complex, Roc, domain of DAPkinase VWA PF00092.28 EJS42740.1 - 9.4e-06 26.0 0.7 3.7e-05 24.1 0.3 2.4 2 0 0 2 2 1 1 von Willebrand factor type A domain AAA_8 PF12780.7 EJS42740.1 - 2e-05 24.0 1.4 7.8 5.7 0.0 6.1 6 0 0 6 6 5 0 P-loop containing dynein motor region D4 PhoH PF02562.16 EJS42740.1 - 4.9e-05 22.9 0.6 6.9 6.1 0.0 4.9 5 0 0 5 5 4 0 PhoH-like protein ResIII PF04851.15 EJS42740.1 - 6.8e-05 22.9 5.4 1.3 9.0 0.3 6.0 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.25 EJS42740.1 - 8.3e-05 22.3 0.0 4.9 6.8 0.1 3.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 EJS42740.1 - 0.00019 21.3 6.7 8.6 6.1 0.0 5.7 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein CPT PF07931.12 EJS42740.1 - 0.00051 19.9 0.4 10 5.9 0.0 5.7 4 1 0 4 4 4 0 Chloramphenicol phosphotransferase-like protein CbiA PF01656.23 EJS42740.1 - 0.0019 18.2 5.0 1.6 8.8 0.0 5.4 5 0 0 5 5 5 1 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.14 EJS42740.1 - 0.0032 16.7 1.8 3 6.9 0.0 4.6 4 0 0 4 4 4 1 PIF1-like helicase dNK PF01712.19 EJS42740.1 - 0.0035 17.2 6.1 15 5.3 0.0 5.9 5 0 0 5 5 5 0 Deoxynucleoside kinase SRPRB PF09439.10 EJS42740.1 - 0.004 16.6 11.2 6.4 6.2 0.2 6.6 7 0 0 7 7 6 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 EJS42740.1 - 0.1 12.5 12.2 3.3 7.6 0.8 5.8 7 0 0 7 7 5 0 NTPase Ago_PAZ PF18309.1 EJS42740.1 - 0.11 13.2 1.8 0.44 11.2 1.8 2.1 1 0 0 1 1 1 0 Argonaute PAZ domain Complex1_LYR_2 PF13233.6 EJS42740.1 - 0.13 13.1 0.6 2.8 8.8 0.6 3.5 1 1 0 1 1 1 0 Complex1_LYR-like T2SSF PF00482.23 EJS42740.1 - 0.15 12.0 0.0 7.3 6.6 0.0 3.3 3 0 0 3 3 2 0 Type II secretion system (T2SS), protein F FtsK_SpoIIIE PF01580.18 EJS42740.1 - 0.25 10.6 7.1 2.9 7.2 0.1 4.9 6 0 0 6 6 5 0 FtsK/SpoIIIE family MobB PF03205.14 EJS42740.1 - 0.26 11.2 8.4 12 5.8 0.4 5.5 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase PF06745.13 EJS42740.1 - 0.72 9.1 10.3 5.4 6.3 0.2 4.5 5 0 0 5 5 4 0 KaiC Pkinase PF00069.25 EJS42741.1 - 1.1e-41 143.0 0.0 1.2e-40 139.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42741.1 - 6.9e-16 58.3 0.0 1.5e-15 57.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJS42741.1 - 0.00048 19.0 0.0 0.00079 18.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EJS42741.1 - 0.051 12.9 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_2 PF00152.20 EJS42742.1 - 2.4e-75 253.6 0.2 4e-75 252.8 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EJS42742.1 - 2.1e-07 30.8 0.2 4.6e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NARP1 PF12569.8 EJS42742.1 - 0.6 8.9 9.7 0.87 8.4 9.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rab5ip PF07019.12 EJS42743.1 - 3.9e-19 69.0 5.8 4.6e-19 68.8 5.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Abhydro_lipase PF04083.16 EJS42744.1 - 6.4e-18 64.1 0.1 1.1e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EJS42744.1 - 2.4e-05 24.1 0.0 4.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tetraspanin PF00335.20 EJS42744.1 - 0.09 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family Preseq_ALAS PF09029.10 EJS42744.1 - 0.21 12.1 0.0 0.43 11.1 0.0 1.4 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence NIF PF03031.18 EJS42745.1 - 2.2e-52 177.0 0.2 5.5e-52 175.7 0.2 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EJS42745.1 - 0.035 14.5 0.1 0.08 13.3 0.1 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DNA_gyraseA_C PF03989.13 EJS42745.1 - 0.057 12.9 0.0 5.5 6.5 0.0 2.5 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller RskA PF10099.9 EJS42745.1 - 0.086 13.1 4.3 0.17 12.2 4.2 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4045 PF13254.6 EJS42745.1 - 0.72 9.4 32.5 0.93 9.1 32.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF4303 PF14136.6 EJS42745.1 - 4.9 6.9 10.1 1.4 8.7 5.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4303) COX17 PF05051.13 EJS42746.1 - 8.1e-23 80.5 8.7 1.1e-22 80.1 8.7 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 EJS42746.1 - 0.00018 21.6 4.6 0.00028 20.9 4.6 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 EJS42746.1 - 0.0004 20.3 4.2 0.001 19.0 0.3 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like DEAD PF00270.29 EJS42747.1 - 1.4e-43 148.7 0.0 3e-43 147.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS42747.1 - 2.3e-27 95.5 0.0 1.8e-26 92.6 0.0 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain PH_12 PF16457.5 EJS42748.1 - 2.8e-08 34.4 0.0 5.9e-07 30.1 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Sfi1 PF08457.10 EJS42749.1 - 1.5e-138 462.9 74.3 5.3e-137 457.7 67.4 3.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Sfi1_C PF10638.9 EJS42749.1 - 7.6e-39 132.7 3.1 3.5e-38 130.6 3.1 2.3 1 0 0 1 1 1 1 Spindle body associated protein C-terminus Dynamin_M PF01031.20 EJS42750.1 - 3.6e-109 364.4 0.0 6.8e-109 363.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EJS42750.1 - 1.6e-55 187.7 0.0 4.9e-55 186.1 0.0 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EJS42750.1 - 1.5e-28 98.7 1.8 4.3e-28 97.3 1.8 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EJS42750.1 - 9.3e-05 22.5 0.8 0.00054 20.0 0.2 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EJS42750.1 - 0.048 13.4 5.5 0.75 9.4 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain CSRNP_N PF16019.5 EJS42750.1 - 0.11 12.4 1.0 0.19 11.6 1.0 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus NOC3p PF07540.11 EJS42751.1 - 1.9e-28 98.7 0.2 1.9e-28 98.7 0.2 3.1 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 EJS42751.1 - 1.5e-24 86.9 0.1 1.5e-24 86.9 0.1 3.3 4 0 0 4 4 4 1 CBF/Mak21 family Focal_AT PF03623.13 EJS42751.1 - 0.14 12.1 3.9 0.077 13.0 0.8 2.2 2 0 0 2 2 2 0 Focal adhesion targeting region 60KD_IMP PF02096.20 EJS42751.1 - 0.42 10.5 1.7 0.54 10.1 0.3 1.9 2 0 0 2 2 2 0 60Kd inner membrane protein DUF5308 PF17233.2 EJS42751.1 - 0.44 10.8 2.6 2.7 8.2 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5308) RR_TM4-6 PF06459.12 EJS42751.1 - 8.7 6.1 27.6 6 6.6 16.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Response_reg PF00072.24 EJS42752.1 - 4.1e-19 68.8 0.1 3.3e-13 49.8 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain SMC_Nse1 PF07574.13 EJS42753.1 - 2.8e-55 187.2 0.1 3.8e-55 186.8 0.1 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EJS42753.1 - 6.7e-14 51.9 10.3 1.1e-13 51.2 10.3 1.4 1 0 0 1 1 1 1 RING-like domain Rpr2 PF04032.16 EJS42753.1 - 3.2 8.1 6.5 14 6.0 6.7 1.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pam16 PF03656.13 EJS42754.1 - 0.00019 21.4 0.0 0.00026 21.0 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EJS42754.1 - 0.00058 19.9 0.0 0.00094 19.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L24e PF01246.20 EJS42755.1 - 8.8e-32 109.1 4.7 8.8e-32 109.1 4.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e TFIIF_alpha PF05793.12 EJS42755.1 - 0.19 10.3 17.9 0.27 9.8 17.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4746 PF15928.5 EJS42755.1 - 0.59 9.5 10.8 0.72 9.2 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AAA_23 PF13476.6 EJS42755.1 - 0.73 10.3 13.4 0.85 10.1 13.4 1.1 1 0 0 1 1 1 0 AAA domain DUF3629 PF12302.8 EJS42755.1 - 1.6 8.1 9.2 0.95 8.9 7.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3629) GATA PF00320.27 EJS42758.1 - 3.3e-15 55.4 0.2 7.4e-15 54.3 0.2 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-ribbon_3 PF13248.6 EJS42758.1 - 0.082 12.3 2.2 4.5 6.8 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain FHA PF00498.26 EJS42759.1 - 2.9e-12 46.7 0.0 4.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain PNP_UDP_1 PF01048.20 EJS42760.1 - 3e-34 118.3 0.0 3.6e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily NPCC PF08058.11 EJS42761.1 - 4.5e-36 123.8 1.5 7e-36 123.1 1.5 1.3 1 0 0 1 1 1 1 Nuclear pore complex component NIF PF03031.18 EJS42762.1 - 1.1e-54 184.4 0.2 1.9e-54 183.7 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Abhydro_lipase PF04083.16 EJS42763.1 - 5e-16 58.0 0.0 9.9e-16 57.1 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EJS42763.1 - 1.6e-05 24.7 0.5 1.6e-05 24.7 0.5 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJS42763.1 - 0.00039 19.7 0.0 0.00073 18.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJS42763.1 - 0.013 16.1 0.0 0.017 15.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family POC3_POC4 PF10448.9 EJS42764.1 - 7.4e-41 139.5 0.2 8.4e-41 139.4 0.2 1.0 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 SBDS PF01172.18 EJS42765.1 - 7.1e-33 112.6 2.5 1.3e-32 111.8 2.5 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EJS42765.1 - 6.7e-29 100.3 2.1 6.7e-29 100.3 2.1 2.1 2 0 0 2 2 2 1 SBDS protein C-terminal domain HlyIII PF03006.20 EJS42766.1 - 3.8e-82 275.4 18.2 4.9e-82 275.0 18.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related zf-UBR PF02207.20 EJS42767.1 - 2.7e-12 46.7 7.6 2.7e-12 46.7 7.6 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-rbx1 PF12678.7 EJS42767.1 - 0.14 12.4 3.2 0.19 12.0 0.3 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain Snf7 PF03357.21 EJS42768.1 - 2e-54 183.8 18.9 2e-54 183.8 18.9 2.0 2 0 0 2 2 2 1 Snf7 DASH_Dad4 PF08650.10 EJS42768.1 - 0.019 14.9 0.6 0.019 14.9 0.6 2.4 3 0 0 3 3 3 0 DASH complex subunit Dad4 CHASE3 PF05227.13 EJS42768.1 - 0.04 13.8 6.7 0.073 13.0 6.1 1.9 1 1 0 1 1 1 0 CHASE3 domain mCpol PF18182.1 EJS42768.1 - 0.33 11.3 4.3 0.39 11.1 1.0 2.3 2 0 0 2 2 2 0 minimal CRISPR polymerase domain Misat_Tub_SegII PF10644.9 EJS42768.1 - 1.3 9.3 5.1 0.31 11.4 0.3 2.2 2 1 0 2 2 2 0 Misato Segment II tubulin-like domain Snapin_Pallidin PF14712.6 EJS42768.1 - 3.6 8.1 17.4 0.4 11.1 7.9 3.4 2 1 2 4 4 4 0 Snapin/Pallidin SNARE PF05739.19 EJS42769.1 - 2.2e-16 59.6 0.6 6.5e-16 58.1 0.6 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EJS42769.1 - 1.2e-06 27.5 0.0 3.3e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 EJS42769.1 - 6.9e-05 23.0 4.4 6.9e-05 23.0 4.4 2.8 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Syntaxin PF00804.25 EJS42769.1 - 0.0002 21.1 1.3 0.0002 21.1 1.3 3.6 1 1 0 3 3 3 1 Syntaxin DUF16 PF01519.16 EJS42769.1 - 0.033 14.7 1.1 0.033 14.7 1.1 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF16 MCPsignal PF00015.21 EJS42769.1 - 0.08 12.8 0.3 0.08 12.8 0.3 3.0 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF745 PF05335.13 EJS42769.1 - 4.7 6.9 18.2 0.99 9.1 5.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Aminotran_1_2 PF00155.21 EJS42770.1 - 2.5e-80 270.4 0.0 2.8e-80 270.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AICARFT_IMPCHas PF01808.18 EJS42771.1 - 4.5e-93 311.9 0.0 7.1e-93 311.3 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EJS42771.1 - 3.7e-26 91.2 0.3 1.2e-25 89.5 0.0 1.9 2 0 0 2 2 2 1 MGS-like domain DKCLD PF08068.12 EJS42771.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 DKCLD (NUC011) domain Ribosomal_L15e PF00827.17 EJS42772.1 - 6.5e-90 300.0 13.0 8.1e-90 299.7 13.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 SNF2_N PF00176.23 EJS42773.1 - 7.8e-67 225.4 0.1 1.3e-66 224.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EJS42773.1 - 9.5e-16 57.5 0.0 6.4e-15 54.9 0.0 2.4 3 0 0 3 3 3 1 HIRAN domain Helicase_C PF00271.31 EJS42773.1 - 7.8e-15 55.2 0.0 1.4e-13 51.1 0.0 2.9 4 0 0 4 4 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 EJS42773.1 - 2.4e-08 34.1 5.9 5.2e-08 33.1 5.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EJS42773.1 - 7.6e-08 32.1 3.2 1.4e-07 31.3 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJS42773.1 - 1.2e-07 31.4 7.2 2.5e-07 30.5 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJS42773.1 - 1.1e-06 28.6 4.8 2.4e-06 27.4 4.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EJS42773.1 - 2.2e-06 27.5 6.7 4.8e-06 26.4 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 EJS42773.1 - 2.1e-05 24.6 0.0 0.00069 19.7 0.0 2.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EJS42773.1 - 0.0018 18.0 6.6 0.004 17.0 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EJS42773.1 - 0.0022 18.1 7.5 0.0055 16.8 7.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EJS42773.1 - 0.014 15.3 4.5 0.027 14.3 4.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EJS42773.1 - 0.019 14.7 6.3 0.04 13.7 6.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EJS42773.1 - 0.02 14.9 1.0 0.046 13.8 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EJS42773.1 - 0.03 14.1 4.9 0.073 12.8 4.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 EJS42773.1 - 0.066 13.5 3.0 0.18 12.1 3.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 EJS42773.1 - 0.17 12.1 3.9 0.51 10.5 3.9 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain Bromodomain PF00439.25 EJS42774.1 - 5.1e-07 29.7 0.1 1.4e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Bromodomain DUF2457 PF10446.9 EJS42774.1 - 0.14 11.3 10.1 0.28 10.3 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nramp PF01566.18 EJS42775.1 - 1.4e-96 323.6 14.0 1.8e-96 323.2 14.0 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein HATPase_c_3 PF13589.6 EJS42776.1 - 5.3e-11 42.5 0.1 2e-10 40.6 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EJS42776.1 - 2.7e-10 39.9 0.3 6e-10 38.8 0.3 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EJS42776.1 - 4.1e-05 24.1 0.1 8.9e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase L1R_F9L PF02442.17 EJS42776.1 - 0.16 11.8 3.6 0.55 10.0 3.6 1.9 1 1 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses COX6B PF02297.17 EJS42777.1 - 8.4e-20 70.8 5.4 9.7e-20 70.6 5.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EJS42777.1 - 0.044 13.8 2.4 0.072 13.1 2.4 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 EJS42777.1 - 0.062 13.3 0.5 0.091 12.7 0.5 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain MYT1 PF08474.11 EJS42777.1 - 0.064 13.2 0.1 0.064 13.2 0.1 1.1 1 0 0 1 1 1 0 Myelin transcription factor 1 Thioredoxin PF00085.20 EJS42778.1 - 1.3e-32 111.9 0.2 1.4e-32 111.7 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EJS42778.1 - 7.4e-08 32.2 0.1 7.9e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EJS42778.1 - 1.9e-07 31.5 0.3 3.9e-06 27.3 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EJS42778.1 - 4e-07 30.3 0.0 0.00012 22.3 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EJS42778.1 - 1.3e-05 25.1 0.1 1.6e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EJS42778.1 - 2.8e-05 23.9 0.1 0.00013 21.7 0.0 1.8 1 1 1 2 2 2 1 Redoxin DIM1 PF02966.16 EJS42778.1 - 0.0019 18.0 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_7 PF13899.6 EJS42778.1 - 0.0061 16.7 0.1 0.0099 16.0 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 EJS42778.1 - 0.0062 16.4 0.1 0.012 15.5 0.1 1.4 1 1 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 EJS42778.1 - 0.026 13.9 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HyaE PF07449.11 EJS42778.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TPP_enzyme_N PF02776.18 EJS42779.1 - 1.6e-32 112.4 0.0 2.8e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EJS42779.1 - 8.3e-28 96.8 0.0 8.8e-27 93.5 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EJS42779.1 - 2.4e-14 53.4 0.0 5.4e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.6 EJS42779.1 - 0.056 13.6 0.2 4 7.6 0.1 2.8 2 0 0 2 2 2 0 OCC1 family HEAT PF02985.22 EJS42780.1 - 0.064 13.5 0.2 11 6.6 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat Cnd3 PF12719.7 EJS42780.1 - 0.071 12.3 6.0 0.31 10.2 0.1 3.0 3 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Phage_GPO PF05929.11 EJS42780.1 - 0.089 12.4 5.2 0.27 10.8 5.2 1.8 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase NeuB PF03102.14 EJS42780.1 - 0.12 11.8 1.9 1.4 8.3 1.7 2.2 2 0 0 2 2 2 0 NeuB family BLOC1_2 PF10046.9 EJS42780.1 - 1.3 9.4 22.4 0.063 13.6 12.1 3.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2781 PF10914.8 EJS42781.1 - 2.7e-40 138.2 9.3 3e-40 138.0 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) WD40 PF00400.32 EJS42783.1 - 7.5e-08 32.9 5.6 16 6.6 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat FA_hydroxylase PF04116.13 EJS42784.1 - 8.2e-22 78.0 17.0 8.2e-22 78.0 17.0 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_hydro_47 PF01532.20 EJS42785.1 - 4.9e-67 226.8 0.0 9.8e-67 225.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 SHMT PF00464.19 EJS42786.1 - 1.8e-211 701.9 0.0 2.1e-211 701.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EJS42786.1 - 6e-08 32.2 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EJS42786.1 - 6.9e-05 22.0 0.0 9.6e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EJS42786.1 - 0.00041 19.7 0.0 0.00091 18.6 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase RNase_T PF00929.24 EJS42787.1 - 2.1e-39 135.7 0.0 2.7e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease tRNA_synthFbeta PF17759.1 EJS42788.1 - 6.8e-40 136.8 0.0 1.3e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EJS42788.1 - 3.4e-31 107.3 1.4 1.9e-27 95.3 0.4 2.4 2 0 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EJS42788.1 - 6.4e-27 94.3 0.1 1.2e-26 93.5 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EJS42788.1 - 1.8e-16 60.2 0.1 1.4e-15 57.3 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase B5 domain LapA_dom PF06305.11 EJS42789.1 - 0.035 13.9 2.5 1.4 8.7 0.3 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain TMEM208_SND2 PF05620.11 EJS42790.1 - 6.5e-44 149.7 1.6 7.3e-44 149.5 1.6 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 SPC22 PF04573.12 EJS42791.1 - 2.5e-55 186.6 6.6 2.9e-55 186.4 6.6 1.0 1 0 0 1 1 1 1 Signal peptidase subunit HIM1 PF08732.10 EJS42791.1 - 0.023 14.2 0.7 0.028 13.9 0.7 1.2 1 0 0 1 1 1 0 HIM1 PPR PF01535.20 EJS42792.1 - 4.2e-10 39.2 3.3 0.83 10.0 0.0 9.6 11 0 0 11 11 11 2 PPR repeat PPR_long PF17177.4 EJS42792.1 - 6.8e-09 35.4 0.7 4.4e-05 22.9 0.0 3.2 2 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 EJS42792.1 - 3.2e-06 27.2 19.2 0.0051 17.0 0.0 8.5 7 2 3 10 10 10 2 PPR repeat family TPR_14 PF13428.6 EJS42792.1 - 0.0019 18.9 0.0 38 5.5 0.0 4.9 3 1 2 5 5 4 0 Tetratricopeptide repeat PPR_3 PF13812.6 EJS42792.1 - 0.0048 16.9 2.2 3.4 7.8 0.0 4.9 4 1 1 5 5 5 1 Pentatricopeptide repeat domain Swm2 PF17083.5 EJS42792.1 - 0.0048 16.9 0.9 0.016 15.2 0.2 2.3 2 0 0 2 2 2 1 Nucleolar protein Swm2 TPR_19 PF14559.6 EJS42792.1 - 0.018 15.5 0.0 5.5 7.6 0.0 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EJS42792.1 - 0.082 13.6 0.2 46 5.0 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat Ribonuc_red_lgN PF00317.21 EJS42792.1 - 0.083 12.9 4.6 6.8 6.8 0.0 4.6 5 0 0 5 5 5 0 Ribonucleotide reductase, all-alpha domain TPR_8 PF13181.6 EJS42792.1 - 0.16 12.2 2.6 6.3 7.3 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat RPM2 PF08579.11 EJS42792.1 - 0.26 11.7 9.0 0.82 10.1 0.8 3.8 4 0 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) VASt PF16016.5 EJS42793.1 - 3.4e-32 112.0 1.1 5.2e-32 111.4 0.5 1.7 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EJS42793.1 - 1e-25 89.8 0.8 2.1e-25 88.8 0.8 1.6 1 0 0 1 1 1 1 GRAM domain Syntaphilin PF15290.6 EJS42793.1 - 0.0098 15.6 3.2 0.023 14.3 3.2 1.6 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp DUF2919 PF11143.8 EJS42793.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) USP8_dimer PF08969.11 EJS42794.1 - 0.00054 20.1 0.0 0.0011 19.1 0.0 1.7 1 1 0 1 1 1 1 USP8 dimerisation domain Ribosomal_L16 PF00252.18 EJS42795.1 - 1.9e-41 141.2 0.0 2.4e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rax2 PF12768.7 EJS42798.1 - 1.7e-57 194.3 1.5 1.7e-57 194.3 1.5 5.8 4 3 2 6 6 6 3 Cortical protein marker for cell polarity Actin PF00022.19 EJS42799.1 - 2.6e-52 177.8 0.0 2.6e-51 174.5 0.0 1.9 1 1 0 1 1 1 1 Actin HSP70 PF00012.20 EJS42800.1 - 1.1e-263 876.0 8.4 1.2e-263 875.8 8.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJS42800.1 - 1.5e-17 63.4 0.0 1.6e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EJS42800.1 - 0.0013 18.5 0.0 0.0048 16.6 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EJS42800.1 - 0.0068 15.4 0.3 0.1 11.5 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 EJS42800.1 - 0.012 16.1 1.3 20 5.7 0.0 3.7 3 1 0 3 3 3 0 Cell division protein FtsA PilM_2 PF11104.8 EJS42800.1 - 0.02 13.9 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; BcrAD_BadFG PF01869.20 EJS42800.1 - 0.038 13.5 0.0 5.9 6.3 0.0 2.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 EJS42800.1 - 0.44 9.8 2.7 0.22 10.7 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF1542 PF07564.11 EJS42800.1 - 0.79 9.9 8.3 0.049 13.7 2.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) MutS_III PF05192.18 EJS42800.1 - 2.5 8.3 7.2 6.6 6.9 1.7 2.4 2 1 0 2 2 2 0 MutS domain III ENTH PF01417.20 EJS42801.1 - 2.3e-36 124.6 2.0 3.4e-36 124.0 2.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EJS42801.1 - 2.3e-05 23.5 0.3 3.2e-05 23.1 0.3 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 EJS42801.1 - 0.0079 16.1 0.7 0.014 15.3 0.7 1.4 1 0 0 1 1 1 1 VHS domain Prp19 PF08606.11 EJS42802.1 - 8.1e-26 89.8 0.1 2e-25 88.6 0.1 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.15 EJS42802.1 - 0.00051 20.2 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain RcbX PF02341.15 EJS42802.1 - 0.08 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 RbcX protein CLP1_P PF16575.5 EJS42803.1 - 7.4e-31 107.4 0.0 1.1e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop G-alpha PF00503.20 EJS42803.1 - 0.0097 15.1 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EJS42803.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EJS42803.1 - 0.04 13.3 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.6 EJS42803.1 - 0.12 12.4 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 EJS42803.1 - 0.18 11.3 0.1 0.37 10.2 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.29 EJS42804.1 - 3.6e-94 312.2 0.0 2.1e-47 160.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS42804.1 - 6.3e-24 83.5 0.4 1.3e-10 40.9 0.0 2.9 2 1 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EJS42804.1 - 7e-15 55.1 0.0 2.4e-07 30.6 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EJS42804.1 - 2.3e-14 54.1 0.3 2.9e-05 24.5 0.0 3.9 3 2 0 3 3 2 2 AAA ATPase domain AAA_2 PF07724.14 EJS42804.1 - 2.6e-11 43.9 0.0 0.00025 21.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EJS42804.1 - 3.6e-10 40.2 1.0 0.014 15.7 0.0 4.9 2 2 3 5 5 5 2 AAA domain AAA_33 PF13671.6 EJS42804.1 - 3.6e-10 40.1 0.0 0.00029 21.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EJS42804.1 - 1.7e-09 37.8 0.2 0.0019 18.2 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 EJS42804.1 - 2.4e-09 37.0 0.1 4.8e-05 23.3 0.0 3.1 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 EJS42804.1 - 2e-08 34.9 0.0 0.00084 19.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.13 EJS42804.1 - 3.2e-08 33.2 1.1 0.00039 19.7 0.0 2.7 3 0 0 3 3 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 EJS42804.1 - 2.1e-07 31.3 0.0 0.015 15.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 EJS42804.1 - 2.3e-07 31.4 0.3 0.019 15.5 0.0 3.5 4 0 0 4 4 2 2 ABC transporter AAA_14 PF13173.6 EJS42804.1 - 2.5e-07 30.8 0.0 0.033 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EJS42804.1 - 3e-06 26.8 0.4 0.031 13.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EJS42804.1 - 3.8e-06 27.0 0.0 0.022 14.7 0.0 2.9 3 0 0 3 3 2 2 Rad17 P-loop domain Zeta_toxin PF06414.12 EJS42804.1 - 4.7e-06 26.0 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 EJS42804.1 - 6.3e-06 26.5 0.0 0.077 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EJS42804.1 - 6.9e-06 25.9 0.1 0.094 12.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_3 PF07726.11 EJS42804.1 - 1.9e-05 24.6 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EJS42804.1 - 2.4e-05 24.8 0.2 0.14 12.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain Cytidylate_kin2 PF13189.6 EJS42804.1 - 2.7e-05 24.4 0.0 0.0019 18.4 0.0 2.9 3 0 0 3 3 2 1 Cytidylate kinase-like family AAA_7 PF12775.7 EJS42804.1 - 4.8e-05 22.9 0.0 0.24 10.9 0.0 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region NACHT PF05729.12 EJS42804.1 - 8e-05 22.6 0.1 0.49 10.3 0.0 3.0 3 0 0 3 3 2 2 NACHT domain TsaE PF02367.17 EJS42804.1 - 0.00011 22.2 0.0 0.71 9.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EJS42804.1 - 0.00011 21.8 0.1 1.3 8.5 0.0 4.0 4 1 1 5 5 4 1 AAA domain SKI PF01202.22 EJS42804.1 - 0.00015 22.0 0.0 0.24 11.5 0.0 3.0 2 0 0 2 2 2 1 Shikimate kinase Viral_helicase1 PF01443.18 EJS42804.1 - 0.00017 21.4 0.0 0.62 9.8 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 EJS42804.1 - 0.00067 18.9 0.0 0.25 10.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EJS42804.1 - 0.00082 19.1 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain CPT PF07931.12 EJS42804.1 - 0.00093 19.1 0.0 0.022 14.6 0.0 2.5 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.26 EJS42804.1 - 0.0013 18.5 0.0 0.84 9.3 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 EJS42804.1 - 0.0013 18.0 0.1 1.1 8.4 0.0 2.9 2 0 0 2 2 2 1 NB-ARC domain SRPRB PF09439.10 EJS42804.1 - 0.002 17.6 0.0 1.1 8.6 0.0 3.4 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit ATPase_2 PF01637.18 EJS42804.1 - 0.0021 18.0 0.1 2.2 8.2 0.0 3.4 3 1 1 4 4 3 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 EJS42804.1 - 0.0021 17.2 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase PF06745.13 EJS42804.1 - 0.0028 17.0 0.1 3.4 7.0 0.0 3.3 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.6 EJS42804.1 - 0.0041 17.2 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin PF02224.18 EJS42804.1 - 0.011 15.5 0.1 1 9.1 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_11 PF13086.6 EJS42804.1 - 0.014 15.2 9.9 0.64 9.8 0.0 3.8 3 1 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 EJS42804.1 - 0.018 14.8 0.0 7.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 EJS42804.1 - 0.023 14.2 0.9 3.2 7.2 0.0 2.8 3 0 0 3 3 2 0 PhoH-like protein AAA_19 PF13245.6 EJS42804.1 - 0.03 14.7 0.1 8.9 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EJS42804.1 - 0.035 14.0 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 NTPase Hydin_ADK PF17213.3 EJS42804.1 - 0.042 14.1 4.1 0.9 9.8 0.0 3.6 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain AFG1_ATPase PF03969.16 EJS42804.1 - 0.046 12.6 0.1 9.9 4.9 0.0 2.6 3 0 0 3 3 2 0 AFG1-like ATPase RsgA_GTPase PF03193.16 EJS42804.1 - 0.083 12.8 0.9 1 9.2 0.0 2.8 3 0 0 3 3 2 0 RsgA GTPase ADK PF00406.22 EJS42804.1 - 0.092 12.8 1.1 26 4.9 0.1 3.3 3 0 0 3 3 3 0 Adenylate kinase FeoB_N PF02421.18 EJS42804.1 - 0.096 12.2 0.1 2.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 EJS42804.1 - 0.14 11.9 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EJS42804.1 - 0.17 12.0 2.2 2.9 8.0 0.1 3.4 4 0 0 4 4 2 0 50S ribosome-binding GTPase MPM1 PF17234.2 EJS42804.1 - 0.18 12.0 4.9 0.64 10.3 4.9 1.9 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 AAA_23 PF13476.6 EJS42804.1 - 1.2 9.6 0.0 1.2 9.6 0.0 4.5 4 1 0 4 4 3 0 AAA domain MEA1 PF06910.11 EJS42804.1 - 6.2 7.5 8.6 0.5 11.0 1.7 2.6 3 0 0 3 3 1 0 Male enhanced antigen 1 (MEA1) KH_1 PF00013.29 EJS42806.1 - 1.1e-06 28.4 6.1 0.011 15.6 0.1 4.4 5 0 0 5 5 5 3 KH domain Phosphodiest PF01663.22 EJS42807.1 - 2.5e-13 50.3 0.9 3.8e-13 49.7 0.9 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EJS42807.1 - 0.0027 17.1 0.4 0.0027 17.1 0.4 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF3557 PF12078.8 EJS42807.1 - 0.2 11.6 2.8 2.4 8.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3557) Saf_2TM PF18303.1 EJS42807.1 - 5 6.7 10.5 9.2 5.8 0.0 4.9 5 0 0 5 5 5 0 SAVED-fused 2TM effector domain Creatinase_N_2 PF16189.5 EJS42808.1 - 6.6e-43 146.6 0.1 7.9e-42 143.1 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EJS42808.1 - 2.5e-39 135.1 0.0 8.4e-39 133.4 0.0 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EJS42808.1 - 2.8e-22 78.5 0.9 1.2e-21 76.5 0.5 2.3 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EJS42808.1 - 5.8e-10 39.9 0.0 6.2e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Fe-S_biosyn PF01521.20 EJS42809.1 - 3.1e-19 69.2 0.0 7.2e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.7 EJS42809.1 - 0.061 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) AAA_2 PF07724.14 EJS42810.1 - 1e-46 159.2 0.0 2.5e-45 154.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EJS42810.1 - 1.1e-27 96.0 0.4 1.1e-27 96.0 0.4 3.2 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 EJS42810.1 - 2.9e-24 86.0 0.2 2.1e-14 54.1 0.1 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EJS42810.1 - 8.8e-24 83.4 1.3 3.4e-23 81.5 1.3 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 EJS42810.1 - 3.6e-15 55.8 7.1 2e-10 40.7 1.3 3.5 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 EJS42810.1 - 1.1e-14 54.6 0.0 2.1e-07 31.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EJS42810.1 - 1.9e-11 44.0 0.2 3.8e-08 33.2 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 EJS42810.1 - 5.6e-08 33.3 8.5 9.1e-05 22.9 0.0 4.9 5 1 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 EJS42810.1 - 2.1e-06 28.1 0.4 0.094 13.0 0.1 4.1 2 2 0 2 2 2 2 AAA domain TniB PF05621.11 EJS42810.1 - 7e-06 25.6 0.1 0.0047 16.4 0.0 4.1 2 1 1 3 3 3 1 Bacterial TniB protein TIP49 PF06068.13 EJS42810.1 - 4.9e-05 22.7 4.0 0.13 11.5 0.0 3.9 4 0 0 4 4 4 2 TIP49 P-loop domain AAA_24 PF13479.6 EJS42810.1 - 0.00015 21.6 0.0 0.13 12.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EJS42810.1 - 0.00052 19.6 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EJS42810.1 - 0.00079 18.9 0.0 2.1 7.7 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EJS42810.1 - 0.0019 18.4 0.1 0.23 11.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EJS42810.1 - 0.003 16.9 0.5 0.42 9.9 0.0 3.5 3 1 0 3 3 3 1 Zeta toxin NACHT PF05729.12 EJS42810.1 - 0.0033 17.4 0.0 1.3 8.9 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_3 PF07726.11 EJS42810.1 - 0.0042 17.0 0.0 0.76 9.6 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 EJS42810.1 - 0.0047 17.0 0.0 0.017 15.2 0.0 1.9 2 0 0 2 2 1 1 Torsin ATPase_2 PF01637.18 EJS42810.1 - 0.012 15.6 6.8 2.5 8.0 0.1 4.4 3 1 0 4 4 4 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EJS42810.1 - 0.014 15.2 0.0 0.83 9.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 EJS42810.1 - 0.027 14.8 0.1 0.93 9.8 0.2 3.1 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 EJS42810.1 - 0.031 14.3 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PEPCK_ATP PF01293.20 EJS42810.1 - 0.033 12.9 0.0 0.069 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Roc PF08477.13 EJS42810.1 - 0.038 14.2 0.0 10 6.4 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EJS42810.1 - 0.056 13.4 0.0 5.1 7.0 0.0 3.1 3 0 0 3 3 2 0 NTPase ABC_tran PF00005.27 EJS42810.1 - 0.2 12.2 3.5 8.6 6.9 0.0 3.8 4 0 0 4 4 3 0 ABC transporter AcylCoA_dehyd_C PF12186.8 EJS42810.1 - 0.86 9.7 4.2 9.9 6.3 0.1 2.6 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal Atg14 PF10186.9 EJS42810.1 - 8.9 5.3 10.2 20 4.2 10.2 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MIP PF00230.20 EJS42811.1 - 4.8e-85 284.9 9.5 6.4e-85 284.5 9.5 1.2 1 0 0 1 1 1 1 Major intrinsic protein AGH PF17558.2 EJS42811.1 - 0.017 15.3 0.4 0.035 14.3 0.4 1.4 1 0 0 1 1 1 0 Androgenic gland hormone Fer2_3 PF13085.6 EJS42812.1 - 2.9e-34 117.3 0.1 5.5e-34 116.4 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EJS42812.1 - 3.4e-09 37.1 8.0 3.4e-09 37.1 8.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EJS42812.1 - 9.9e-08 32.3 9.0 9.9e-08 32.3 9.0 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EJS42812.1 - 1.2e-07 31.7 4.2 1.2e-07 31.7 4.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EJS42812.1 - 0.00048 20.0 4.0 0.0043 17.0 1.1 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 EJS42812.1 - 0.0012 19.4 6.5 0.0012 19.4 6.5 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EJS42812.1 - 0.11 12.7 14.4 0.034 14.3 9.1 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain SHR-BD PF06650.12 EJS42813.1 - 1.9e-92 309.5 10.5 9e-90 300.7 3.8 3.0 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 EJS42813.1 - 2.3e-80 269.4 21.1 2.7e-78 262.7 0.5 6.9 4 1 2 6 6 6 3 Repeating coiled region of VPS13 VPS13 PF16908.5 EJS42813.1 - 1.4e-76 257.4 6.5 4.6e-73 245.9 0.5 4.6 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EJS42813.1 - 3.6e-70 235.3 5.2 4.1e-65 218.9 0.2 3.4 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EJS42813.1 - 8e-39 132.4 0.1 4.7e-38 129.9 0.1 2.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EJS42813.1 - 0.00031 21.0 0.1 0.00083 19.7 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain MIP PF00230.20 EJS42814.1 - 1.7e-23 83.5 6.5 2e-23 83.3 6.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein ABC2_membrane_3 PF12698.7 EJS42814.1 - 0.93 8.5 7.3 1.1 8.3 7.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein FAD_binding_8 PF08022.12 EJS42815.1 - 1.2e-28 99.3 0.0 3.2e-28 98.0 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EJS42815.1 - 6.5e-24 84.4 14.5 6.5e-24 84.4 14.5 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EJS42815.1 - 1.5e-22 80.4 0.0 3.7e-22 79.1 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EJS42815.1 - 0.14 12.8 0.0 2.3 8.9 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain TMIE PF16038.5 EJS42815.1 - 3.5 7.5 5.3 19 5.2 0.0 3.5 2 1 1 3 3 3 0 TMIE protein ATS3 PF06232.11 EJS42816.1 - 0.03 14.2 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 Embryo-specific protein 3, (ATS3) Defb50 PF17546.2 EJS42816.1 - 0.16 11.9 1.5 0.2 11.6 0.5 1.7 2 0 0 2 2 2 0 Beta defensin 50 DUF3323 PF11796.8 EJS42816.1 - 0.21 11.5 0.0 0.28 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) ABC_membrane PF00664.23 EJS42817.1 - 5.9e-57 193.4 54.9 3e-38 132.1 12.9 4.3 5 0 0 5 5 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EJS42817.1 - 8.5e-56 188.3 0.5 4.3e-33 114.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.6 EJS42817.1 - 7.7e-11 42.9 3.1 4.4e-05 24.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EJS42817.1 - 4.8e-10 39.7 3.8 0.0053 16.6 0.2 3.6 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJS42817.1 - 3.3e-09 36.5 5.9 0.00039 19.9 2.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJS42817.1 - 2.4e-07 30.4 0.5 0.0048 16.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EJS42817.1 - 1.3e-06 28.4 0.0 0.021 14.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EJS42817.1 - 1.5e-06 28.3 0.1 0.0064 16.6 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 EJS42817.1 - 3.4e-05 23.1 0.0 0.038 13.0 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_15 PF13175.6 EJS42817.1 - 4.5e-05 23.3 13.6 0.0052 16.5 0.2 3.5 4 0 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 EJS42817.1 - 4.6e-05 23.7 0.3 0.55 10.5 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EJS42817.1 - 5.1e-05 23.7 0.1 0.82 10.0 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain Dynamin_N PF00350.23 EJS42817.1 - 0.00032 20.8 0.1 0.13 12.3 0.1 2.8 2 0 0 2 2 2 1 Dynamin family ATP_bind_1 PF03029.17 EJS42817.1 - 0.00066 19.5 0.0 4.3 7.0 0.0 3.5 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein DUF87 PF01935.17 EJS42817.1 - 0.00092 19.4 4.4 0.31 11.1 0.0 3.1 3 0 0 3 3 2 2 Helicase HerA, central domain AAA_30 PF13604.6 EJS42817.1 - 0.0017 18.1 0.1 2.2 8.0 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EJS42817.1 - 0.0021 17.6 0.2 0.8 9.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EJS42817.1 - 0.0026 17.3 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EJS42817.1 - 0.0037 17.7 0.9 4.5 7.7 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 EJS42817.1 - 0.0057 16.0 0.1 3.9 6.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EJS42817.1 - 0.011 15.1 0.0 3.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.15 EJS42817.1 - 0.015 15.3 0.5 5 7.1 0.0 3.5 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 EJS42817.1 - 0.03 14.5 0.0 3.2 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EJS42817.1 - 0.031 13.9 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EJS42817.1 - 0.032 13.8 2.0 1.5 8.4 0.1 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 EJS42817.1 - 0.034 13.0 0.0 1.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein IstB_IS21 PF01695.17 EJS42817.1 - 0.037 13.7 0.7 7.9 6.2 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_24 PF13479.6 EJS42817.1 - 0.042 13.6 0.1 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EJS42817.1 - 0.043 14.0 0.3 18 5.6 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 EJS42817.1 - 0.061 12.2 0.0 6.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.16 EJS42817.1 - 0.1 12.1 1.0 1.1 8.7 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein AAA_18 PF13238.6 EJS42817.1 - 0.11 13.0 0.4 24 5.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 EJS42817.1 - 0.11 11.4 0.1 0.24 10.3 0.0 1.5 2 0 0 2 2 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RRM_1 PF00076.22 EJS42818.1 - 4.8e-19 67.9 4.8 3.7e-16 58.7 0.3 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EJS42818.1 - 0.0021 17.9 2.7 0.64 9.8 0.4 2.3 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain PNMA PF14893.6 EJS42818.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 PNMA TauD PF02668.16 EJS42819.1 - 5.6e-52 177.2 1.3 6.9e-52 176.9 1.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Epimerase PF01370.21 EJS42820.1 - 2.1e-15 56.8 0.0 1.7e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EJS42820.1 - 2.3e-10 39.9 0.1 6.9e-10 38.4 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EJS42820.1 - 4.2e-09 36.5 0.0 5.8e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EJS42820.1 - 1.9e-08 34.1 0.0 5.7e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EJS42820.1 - 3.2e-05 23.5 0.1 6.9e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EJS42820.1 - 4.1e-05 22.8 0.0 0.00015 21.0 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EJS42820.1 - 0.00054 19.2 0.0 0.00089 18.5 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EJS42820.1 - 0.00085 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 EJS42820.1 - 0.0063 17.1 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EJS42820.1 - 0.023 13.8 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 EJS42820.1 - 0.024 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 EJS42820.1 - 0.026 14.8 0.1 0.053 13.8 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain MFS_1 PF07690.16 EJS42821.1 - 6.6e-18 64.8 37.3 6.6e-18 64.8 37.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EJS42821.1 - 1.4e-06 27.9 2.4 1.4e-06 27.9 2.4 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CPP1-like PF11833.8 EJS42821.1 - 0.14 11.8 8.8 0.019 14.6 3.5 2.3 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Myb_DNA-binding PF00249.31 EJS42822.1 - 1.4e-29 102.0 9.2 4.1e-13 49.3 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJS42822.1 - 1.8e-27 95.4 2.2 6.6e-10 39.1 0.0 3.8 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EJS42822.1 - 0.0022 18.0 0.2 4.4 7.4 0.0 3.6 2 1 1 3 3 3 1 SLIDE Rap1_C PF11626.8 EJS42822.1 - 0.022 14.8 1.3 3 8.0 0.1 2.8 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 EJS42822.1 - 0.056 13.6 0.5 10 6.4 0.1 3.6 3 1 1 4 4 4 0 SANT/Myb-like domain of DAMP1 DUF1831 PF08866.10 EJS42822.1 - 0.084 13.3 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Putative amino acid metabolism Myb_DNA-bind_5 PF13873.6 EJS42822.1 - 0.25 11.5 3.8 0.93 9.6 0.5 3.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain SKG6 PF08693.10 EJS42823.1 - 3.1e-05 23.3 4.5 7.1e-05 22.1 4.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LapA_dom PF06305.11 EJS42823.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Vpu PF00558.19 EJS42823.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 Vpu protein TMEM51 PF15345.6 EJS42823.1 - 1.4 8.7 11.7 0.042 13.7 3.6 2.5 3 0 0 3 3 3 0 Transmembrane protein 51 Ribosomal_L1 PF00687.21 EJS42824.1 - 2.6e-43 148.2 0.5 3.2e-43 147.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Glyco_transf_15 PF01793.16 EJS42825.1 - 9.5e-104 347.1 16.1 1.2e-103 346.8 16.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TFA2_Winged_2 PF18121.1 EJS42826.1 - 3.3e-21 74.8 0.9 8.5e-21 73.4 0.1 2.1 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EJS42826.1 - 8.3e-17 61.2 0.4 1.8e-16 60.1 0.4 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain HTH_15 PF12324.8 EJS42826.1 - 0.028 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Las1 PF04031.13 EJS42827.1 - 2e-48 164.4 0.4 5.6e-48 162.9 0.4 1.8 1 0 0 1 1 1 1 Las1-like Secretin_N_2 PF07655.13 EJS42827.1 - 0.12 12.9 2.6 0.16 12.5 0.6 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Zn_clus PF00172.18 EJS42828.1 - 2.1e-08 34.1 7.5 5.4e-08 32.8 7.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pam17 PF08566.10 EJS42829.1 - 2.3e-66 222.7 0.0 3.2e-66 222.3 0.0 1.2 1 1 0 1 1 1 1 Mitochondrial import protein Pam17 peroxidase PF00141.23 EJS42830.1 - 2.8e-41 141.7 0.0 4.7e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Mad3_BUB1_I PF08311.12 EJS42830.1 - 0.12 12.4 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 Acyltransferase PF01553.21 EJS42831.1 - 3.1e-06 26.8 0.0 2.5e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase TRAPP PF04051.16 EJS42832.1 - 4.3e-32 110.8 0.0 6.1e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Hydrolase_like PF13242.6 EJS42833.1 - 2.4e-27 94.8 0.0 4.6e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EJS42833.1 - 9.6e-25 86.6 0.0 1.7e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EJS42833.1 - 0.0026 17.9 0.0 0.084 13.0 0.0 2.9 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJS42833.1 - 0.03 14.6 0.0 5.7 7.2 0.0 2.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase CIAPIN1 PF05093.13 EJS42834.1 - 2.4e-38 130.7 5.2 2.4e-38 130.7 5.2 2.0 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EJS42834.1 - 2.2e-31 108.9 0.1 3.7e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus GAIN_A PF18619.1 EJS42834.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A zf-CSL PF05207.13 EJS42834.1 - 0.45 10.3 5.6 1.9 8.3 4.6 2.5 1 1 0 1 1 1 0 CSL zinc finger ATP19 PF11022.8 EJS42834.1 - 1.1 9.7 5.4 36 4.8 0.9 3.5 3 0 0 3 3 3 0 ATP synthase subunit K DUF2340 PF10209.9 EJS42835.1 - 1.9e-53 180.0 2.4 2.4e-53 179.7 2.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Peptidase_C13 PF01650.18 EJS42835.1 - 0.0055 16.3 1.4 0.027 14.0 0.6 1.9 1 1 1 2 2 2 1 Peptidase C13 family GST_N_2 PF13409.6 EJS42837.1 - 9.9e-24 83.4 0.0 3.6e-23 81.6 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJS42837.1 - 1.6e-12 47.3 0.0 3.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EJS42837.1 - 0.0079 16.6 0.0 0.85 10.1 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EJS42837.1 - 0.071 13.3 0.1 0.24 11.6 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_63N PF16923.5 EJS42838.1 - 0.068 13.2 0.5 0.11 12.6 0.1 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 63 N-terminal domain Lactamase_B_4 PF13691.6 EJS42839.1 - 2.6e-27 94.3 0.0 6.5e-27 93.0 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EJS42839.1 - 3.4e-11 43.0 0.0 0.00028 20.5 0.0 2.7 3 0 0 3 3 3 2 Beta-lactamase superfamily domain THF_DHG_CYH PF00763.23 EJS42840.1 - 2.2e-22 79.5 0.0 5e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EJS42840.1 - 8e-18 64.3 0.0 1.1e-10 41.0 0.0 2.5 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CdiI_N PF18228.1 EJS42840.1 - 0.025 14.4 0.1 3.7 7.4 0.1 2.3 2 0 0 2 2 2 0 CdiI N-terminal domain Brix PF04427.18 EJS42841.1 - 3.3e-39 135.0 1.1 4.6e-39 134.5 1.1 1.2 1 0 0 1 1 1 1 Brix domain Nucleoporin_N PF08801.11 EJS42842.1 - 6.3e-67 226.2 7.8 9.6e-67 225.6 7.8 1.2 1 0 0 1 1 1 1 Nup133 N terminal like HsdM_N PF12161.8 EJS42842.1 - 0.035 14.7 1.9 0.074 13.7 0.6 2.3 2 0 0 2 2 2 0 HsdM N-terminal domain CHAP PF05257.16 EJS42842.1 - 0.18 12.4 0.0 0.75 10.4 0.0 2.1 1 0 0 1 1 1 0 CHAP domain DASH_Dad2 PF08654.10 EJS42843.1 - 2.3e-28 98.5 3.1 4e-28 97.7 3.1 1.4 1 1 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 EJS42843.1 - 0.00022 20.9 2.5 0.00036 20.2 2.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 Ran-binding PF05508.11 EJS42843.1 - 0.018 14.0 0.5 0.024 13.6 0.5 1.1 1 0 0 1 1 1 0 RanGTP-binding protein DUF1664 PF07889.12 EJS42843.1 - 0.048 13.7 1.6 0.067 13.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Vps51 PF08700.11 EJS42843.1 - 0.079 13.1 0.8 0.22 11.6 0.8 1.8 1 1 0 1 1 1 0 Vps51/Vps67 GTP_EFTU PF00009.27 EJS42844.1 - 6.3e-43 146.6 0.0 1.1e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EJS42844.1 - 2.2e-13 50.3 2.9 5.3e-13 49.1 2.9 1.6 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 EJS42844.1 - 1e-08 35.2 0.0 0.00012 22.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 EJS42844.1 - 2.5e-08 34.2 0.0 2.2e-07 31.2 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu C-terminal domain Roc PF08477.13 EJS42844.1 - 0.0005 20.3 0.1 0.097 12.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 EJS42844.1 - 0.002 18.5 0.0 0.0047 17.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 EJS42844.1 - 0.0035 16.9 0.3 0.054 13.1 0.0 2.5 3 0 0 3 3 3 1 Ras family RsgA_GTPase PF03193.16 EJS42844.1 - 0.0042 17.0 0.5 0.35 10.8 0.0 3.1 3 1 0 3 3 3 1 RsgA GTPase SRPRB PF09439.10 EJS42844.1 - 0.019 14.4 0.1 1.6 8.2 0.1 2.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EJS42844.1 - 0.023 14.7 0.3 4.7 7.2 0.0 2.8 2 1 1 3 3 3 0 Dynamin family FeoB_N PF02421.18 EJS42844.1 - 0.034 13.7 0.3 0.57 9.7 0.1 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 EJS42844.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Septin MRP-L20 PF12824.7 EJS42845.1 - 2.5e-44 151.4 2.8 2.9e-44 151.1 2.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 SNARE_assoc PF09335.11 EJS42846.1 - 3.8e-15 56.4 5.5 3.8e-15 56.4 5.5 2.8 2 1 1 3 3 3 1 SNARE associated Golgi protein TctB PF07331.11 EJS42846.1 - 8e-05 22.9 10.1 8e-05 22.9 10.1 2.1 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family DUF3856 PF12968.7 EJS42846.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) SWI-SNF_Ssr4 PF08549.10 EJS42846.1 - 0.24 10.0 0.1 0.32 9.6 0.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Tetraspanin PF00335.20 EJS42846.1 - 0.29 10.8 6.9 3.7 7.2 4.7 2.3 2 0 0 2 2 2 0 Tetraspanin family DUF3040 PF11239.8 EJS42846.1 - 0.85 9.9 3.4 0.83 10.0 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF2976 PF11190.8 EJS42846.1 - 0.95 9.3 4.8 1.7 8.5 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF3810 PF12725.7 EJS42846.1 - 4.9 6.4 6.3 3.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) LIM PF00412.22 EJS42847.1 - 1.1e-11 44.8 25.2 1e-06 28.8 12.1 2.4 2 0 0 2 2 2 2 LIM domain Mfa1 PF17445.2 EJS42848.1 - 0.059 13.4 0.1 3.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Mating factor A1 PTR2 PF00854.21 EJS42849.1 - 1.2e-110 370.1 15.8 1.2e-110 370.1 15.8 1.8 2 1 0 2 2 2 1 POT family DUF3043 PF11241.8 EJS42849.1 - 0.26 11.3 0.1 0.75 9.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PIN_4 PF13638.6 EJS42850.1 - 1.8e-11 44.4 0.3 1.8e-11 44.4 0.3 3.0 3 0 0 3 3 3 1 PIN domain Glyc_hyd_38C_2 PF18230.1 EJS42850.1 - 0.093 12.8 0.1 1.2 9.3 0.0 2.8 4 0 0 4 4 4 0 Glycosyl hydrolases family 38 C-terminal sub-domain Acetyltransf_11 PF13720.6 EJS42850.1 - 0.12 12.8 0.2 0.39 11.2 0.2 1.8 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PHD PF00628.29 EJS42851.1 - 1.5e-10 40.8 8.9 3.1e-10 39.8 8.9 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 EJS42851.1 - 5e-07 30.3 1.7 5e-07 30.3 1.7 3.0 2 1 1 3 3 3 1 SET domain PHD_2 PF13831.6 EJS42851.1 - 0.00014 21.3 2.7 0.00028 20.4 2.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EJS42851.1 - 0.1 12.6 3.5 0.26 11.3 3.5 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger UNC-50 PF05216.13 EJS42852.1 - 1.9e-84 282.7 22.4 2.2e-84 282.4 22.4 1.0 1 0 0 1 1 1 1 UNC-50 family Snf7 PF03357.21 EJS42853.1 - 1.9e-09 37.3 18.9 2.9e-09 36.7 18.9 1.3 1 0 0 1 1 1 1 Snf7 T7SS_ESX_EspC PF10824.8 EJS42853.1 - 0.043 14.3 1.6 0.069 13.6 0.1 2.2 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm ECH_2 PF16113.5 EJS42853.1 - 0.14 11.6 4.7 0.16 11.4 4.7 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF948 PF06103.11 EJS42853.1 - 0.56 10.5 9.6 0.64 10.3 0.8 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) GrpE PF01025.19 EJS42853.1 - 1.2 8.8 12.9 0.43 10.2 9.8 1.7 1 1 1 2 2 2 0 GrpE SHE3 PF17078.5 EJS42853.1 - 2.1 8.0 17.2 4.2 7.0 17.1 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Peptidase_M22 PF00814.25 EJS42854.1 - 6.1e-87 291.8 0.0 7.4e-87 291.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EJS42854.1 - 0.04 13.6 0.1 0.065 12.9 0.1 1.3 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus AA_permease PF00324.21 EJS42855.1 - 3.4e-157 523.9 37.0 3.9e-157 523.7 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS42855.1 - 5.9e-41 140.7 36.6 8e-41 140.2 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease His_Phos_1 PF00300.22 EJS42856.1 - 1.2e-33 116.4 0.2 1.6e-33 116.0 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lectin_leg-like PF03388.13 EJS42857.1 - 1.8e-15 57.0 0.0 9.9e-07 28.3 0.0 2.2 2 0 0 2 2 2 2 Legume-like lectin family Bact_lectin PF18483.1 EJS42857.1 - 4e-05 23.7 0.5 5.6e-05 23.2 0.5 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EJS42857.1 - 0.00017 21.2 0.2 0.00033 20.3 0.2 1.7 1 1 0 1 1 1 1 Legume lectin domain PET10 PF17316.2 EJS42859.1 - 1e-108 362.6 0.4 1.2e-108 362.4 0.4 1.0 1 0 0 1 1 1 1 Petite colonies protein 10 NAP PF00956.18 EJS42860.1 - 8.8e-85 284.1 7.3 8.8e-85 284.1 7.3 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF349 PF03993.12 EJS42860.1 - 3.9 7.8 7.5 3.8 7.9 0.1 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) DUF2457 PF10446.9 EJS42860.1 - 9.8 5.2 23.3 21 4.1 23.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1687 PF07955.11 EJS42861.1 - 1.2e-26 93.7 0.5 1.5e-26 93.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) TrkH PF02386.16 EJS42862.1 - 5e-188 625.6 2.9 1e-186 621.3 0.1 2.1 2 0 0 2 2 2 2 Cation transport protein PBP1_TM PF14812.6 EJS42862.1 - 0.021 15.2 0.8 0.72 10.3 0.0 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_carr PF00153.27 EJS42863.1 - 1.9e-60 200.8 2.0 1.6e-20 72.8 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein PAP2 PF01569.21 EJS42864.1 - 1e-14 54.5 3.6 2.1e-14 53.4 3.6 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EJS42864.1 - 0.0045 16.7 1.2 0.011 15.4 1.2 1.7 1 0 0 1 1 1 1 PAP2 superfamily Fer4_5 PF12801.7 EJS42864.1 - 0.0077 16.2 1.8 0.039 13.9 1.8 2.3 1 0 0 1 1 1 1 4Fe-4S binding domain AAA_6 PF12774.7 EJS42865.1 - 4.8e-102 341.3 0.0 1.5e-99 333.1 0.0 3.4 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EJS42865.1 - 1.5e-84 284.4 14.6 1.5e-84 284.4 14.6 5.1 7 0 0 7 7 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EJS42865.1 - 4.7e-53 179.6 1.7 4.7e-53 179.6 1.7 4.2 6 0 0 6 6 4 1 ATP-binding dynein motor region DHC_N1 PF08385.12 EJS42865.1 - 4.6e-49 167.5 17.4 4.6e-49 167.5 17.4 4.7 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 EJS42865.1 - 3.1e-42 144.7 0.2 2.4e-41 141.8 0.1 2.8 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EJS42865.1 - 8.9e-39 132.9 0.3 1.2e-31 109.7 0.0 4.9 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_5 PF07728.14 EJS42865.1 - 4.3e-29 101.3 0.2 2.7e-10 40.4 0.0 6.7 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) MT PF12777.7 EJS42865.1 - 6e-25 88.0 8.2 1.1e-24 87.1 8.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA PF00004.29 EJS42865.1 - 1.1e-17 64.6 2.7 0.00028 21.3 0.0 7.4 7 0 0 7 7 6 4 ATPase family associated with various cellular activities (AAA) AAA_lid_11 PF18198.1 EJS42865.1 - 1.3e-16 60.9 0.0 6.2e-16 58.6 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EJS42865.1 - 2.2e-14 53.6 0.0 1.9e-11 44.1 0.0 3.4 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 EJS42865.1 - 4.7e-14 52.8 13.0 0.00043 20.6 0.0 7.6 6 1 0 7 7 6 4 AAA domain AAA_16 PF13191.6 EJS42865.1 - 6.8e-11 42.8 1.8 0.45 10.9 0.0 6.1 5 1 0 5 5 4 3 AAA ATPase domain AAA_18 PF13238.6 EJS42865.1 - 1.3e-08 35.4 1.5 0.78 10.3 0.0 5.7 6 0 0 6 6 4 2 AAA domain AAA_30 PF13604.6 EJS42865.1 - 8.7e-08 32.1 0.6 0.56 9.9 0.0 4.5 4 0 0 4 4 4 2 AAA domain AAA_lid_1 PF17857.1 EJS42865.1 - 1e-06 28.9 0.0 5.4e-05 23.3 0.0 3.7 3 0 0 3 3 2 1 AAA+ lid domain RNA_helicase PF00910.22 EJS42865.1 - 4.2e-06 27.1 0.2 5.9 7.3 0.0 5.3 4 0 0 4 4 4 0 RNA helicase AAA_33 PF13671.6 EJS42865.1 - 4.6e-06 26.9 0.1 0.82 9.8 0.0 4.8 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.12 EJS42865.1 - 5.2e-06 25.9 0.0 1.2 8.4 0.0 4.5 4 0 0 4 4 4 2 Zeta toxin AAA_19 PF13245.6 EJS42865.1 - 1e-05 25.9 6.6 2.1 8.7 0.1 6.1 5 1 0 5 5 5 2 AAA domain AAA_24 PF13479.6 EJS42865.1 - 1.7e-05 24.6 4.2 0.44 10.2 0.0 5.5 5 0 0 5 5 5 1 AAA domain IstB_IS21 PF01695.17 EJS42865.1 - 2e-05 24.4 0.1 0.088 12.5 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 EJS42865.1 - 0.00041 19.8 0.2 2.3 7.5 0.0 4.3 4 1 0 4 4 4 1 FtsK/SpoIIIE family TsaE PF02367.17 EJS42865.1 - 0.00052 20.0 0.5 17 5.4 0.0 4.6 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EJS42865.1 - 0.0012 19.4 0.2 7.6 7.0 0.0 4.8 4 0 0 4 4 3 0 ABC transporter AAA_28 PF13521.6 EJS42865.1 - 0.0026 18.0 0.2 27 5.0 0.0 4.0 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 EJS42865.1 - 0.0059 16.8 0.6 14 5.9 0.0 4.1 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 EJS42865.1 - 0.0059 16.0 1.0 0.81 9.0 0.0 3.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EJS42865.1 - 0.0094 15.7 0.1 45 3.9 0.0 4.0 4 0 0 4 4 3 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EJS42865.1 - 0.014 15.0 0.8 2.5 7.7 0.0 3.9 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 EJS42865.1 - 0.022 14.7 9.3 2 8.3 0.0 5.3 6 0 0 6 6 5 0 NACHT domain PduV-EutP PF10662.9 EJS42865.1 - 0.041 13.6 0.3 9.4 6.0 0.0 3.7 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EJS42865.1 - 0.043 13.4 0.0 0.49 10.0 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3137 PF11335.8 EJS42865.1 - 0.047 13.6 2.8 0.5 10.3 0.0 3.9 3 0 0 3 3 2 0 Protein of unknown function (DUF3137) T2SSE PF00437.20 EJS42865.1 - 0.065 12.3 7.5 0.36 9.8 0.0 4.4 6 0 0 6 6 4 0 Type II/IV secretion system protein RuvB_N PF05496.12 EJS42865.1 - 0.1 12.3 0.0 6.2 6.6 0.0 2.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 EJS42865.1 - 0.15 12.0 13.7 0.57 10.2 0.0 5.8 6 1 0 6 6 4 0 Type III restriction enzyme, res subunit DASH_Dad1 PF08649.10 EJS42865.1 - 0.97 9.7 8.6 11 6.3 0.0 4.6 4 0 0 4 4 2 0 DASH complex subunit Dad1 Ras PF00071.22 EJS42866.1 - 1.2e-50 171.3 0.0 1.5e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS42866.1 - 2e-24 86.1 0.0 2.9e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS42866.1 - 7.2e-06 25.6 0.0 1.3e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Glyco_transf_8 PF01501.20 EJS42867.1 - 1.9e-30 106.3 0.0 1.9e-30 106.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 NDK PF00334.19 EJS42868.1 - 2.1e-55 186.4 0.0 2.5e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Bap31 PF05529.12 EJS42870.1 - 3.1e-26 91.8 4.4 3.1e-26 91.8 4.4 1.4 1 1 0 1 1 1 1 Bap31/Bap29 transmembrane region TACC_C PF05010.14 EJS42870.1 - 0.00041 20.2 3.7 0.00056 19.7 3.7 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BLOC1_2 PF10046.9 EJS42870.1 - 0.01 16.1 3.7 0.016 15.5 3.7 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MscS_TM PF12794.7 EJS42870.1 - 0.015 14.1 2.4 0.84 8.4 0.3 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF4298 PF14131.6 EJS42870.1 - 0.032 14.2 1.8 0.055 13.4 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) Sec2p PF06428.11 EJS42870.1 - 0.033 14.1 5.4 0.061 13.3 5.4 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Rpp20 PF12328.8 EJS42870.1 - 0.034 14.1 3.3 0.052 13.5 3.3 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF2203 PF09969.9 EJS42870.1 - 0.12 13.1 2.9 0.68 10.7 2.3 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Oxidored_q4 PF00507.19 EJS42870.1 - 0.32 11.2 2.5 0.75 10.0 2.5 1.6 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF4407 PF14362.6 EJS42870.1 - 0.32 10.3 7.4 0.016 14.6 2.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CHD5 PF04420.14 EJS42870.1 - 0.36 10.7 4.0 0.23 11.3 1.9 1.8 2 0 0 2 2 2 0 CHD5-like protein UPF0242 PF06785.11 EJS42870.1 - 1.5 8.9 9.3 2.5 8.2 9.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Presenilin PF01080.17 EJS42871.1 - 0.64 8.7 5.9 0.81 8.4 5.9 1.2 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 EJS42871.1 - 7.4 5.8 11.6 9.3 5.5 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2 PF00096.26 EJS42872.1 - 7.4e-09 35.6 21.0 1.1e-06 28.7 2.7 3.5 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJS42872.1 - 1e-06 28.9 19.0 4.5e-06 26.8 3.0 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJS42872.1 - 3.3e-06 27.5 19.1 0.0021 18.8 1.9 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HE PF16278.5 EJS42872.1 - 0.00059 20.2 8.7 0.0032 17.9 0.6 2.7 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 EJS42872.1 - 0.0062 16.5 16.0 0.012 15.7 0.4 3.1 3 0 0 3 3 2 2 BED zinc finger zf-C2H2_jaz PF12171.8 EJS42872.1 - 0.01 16.1 17.0 0.057 13.7 2.9 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJS42872.1 - 0.019 15.4 5.8 1.6 9.2 1.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type GAGA PF09237.11 EJS42872.1 - 0.11 12.3 2.5 7.9 6.4 0.1 3.1 2 1 1 3 3 3 0 GAGA factor zf-LYAR PF08790.11 EJS42872.1 - 0.17 11.8 3.6 5.8 6.9 0.2 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 EJS42872.1 - 0.69 9.6 6.1 4.3 7.1 0.5 2.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain PyrI_C PF02748.15 EJS42872.1 - 1.4 8.9 4.6 3.3 7.7 0.3 2.7 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.6 EJS42872.1 - 2.6 8.2 12.4 0.75 9.9 4.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EJS42872.1 - 6.4 7.5 8.9 1.4 9.6 1.4 3.5 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 EJS42872.1 - 6.6 5.1 8.8 6.9 5.1 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF629) BLI1 PF17324.2 EJS42873.1 - 4.4e-34 117.5 10.7 4.8e-34 117.3 10.7 1.0 1 0 0 1 1 1 1 BLOC-1 interactor 1 PHA_gran_rgn PF09650.10 EJS42873.1 - 0.00059 20.1 0.2 0.016 15.5 0.2 2.1 1 1 1 2 2 2 1 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) FliD_N PF02465.18 EJS42873.1 - 0.2 12.3 3.2 2 9.2 0.2 2.1 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus F_bP_aldolase PF01116.20 EJS42874.1 - 3.6e-86 289.1 0.0 4e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DWNN PF08783.11 EJS42875.1 - 8.4e-31 106.1 2.2 1.1e-30 105.7 0.1 2.2 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 EJS42875.1 - 2.2e-06 27.4 7.0 2.2e-06 27.4 7.0 1.8 2 0 0 2 2 2 1 Zinc knuckle U-box PF04564.15 EJS42875.1 - 0.00059 20.0 0.2 0.0015 18.7 0.0 1.8 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 EJS42875.1 - 0.00085 19.1 0.3 0.0021 17.8 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CCHC PF00098.23 EJS42875.1 - 0.00085 19.3 3.3 0.0021 18.1 3.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Rubredoxin PF00301.20 EJS42875.1 - 0.018 15.0 4.2 0.56 10.3 0.0 3.1 3 0 0 3 3 3 0 Rubredoxin zf-CCHC_5 PF14787.6 EJS42875.1 - 0.018 14.7 0.5 0.047 13.4 0.5 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 EJS42875.1 - 0.044 13.7 0.1 0.09 12.8 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-DNL PF05180.12 EJS42875.1 - 0.049 13.6 1.2 0.066 13.2 0.2 1.8 2 0 0 2 2 2 0 DNL zinc finger TF_Zn_Ribbon PF08271.12 EJS42875.1 - 4.7 6.8 6.5 0.81 9.3 0.7 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding TFIIA_gamma_C PF02751.14 EJS42876.1 - 8.3e-24 83.5 0.4 1.4e-23 82.8 0.4 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EJS42876.1 - 1.5e-22 79.3 0.2 2e-22 78.9 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Transketolase_C PF02780.20 EJS42876.1 - 0.039 13.8 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Transketolase, C-terminal domain TCTP PF00838.17 EJS42878.1 - 3.5e-72 242.2 3.3 3.9e-72 242.0 3.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein RcbX PF02341.15 EJS42878.1 - 0.053 13.8 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 RbcX protein CUE PF02845.16 EJS42879.1 - 1.5e-05 24.6 0.0 3.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 CUE domain UPF0203 PF05254.12 EJS42880.1 - 1.2e-27 95.9 3.3 1.4e-27 95.7 3.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 EJS42880.1 - 0.0011 19.1 0.2 0.0017 18.5 0.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 EJS42880.1 - 0.0088 16.0 1.4 0.3 11.1 0.6 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like PaREP1 PF05942.11 EJS42880.1 - 0.039 13.9 0.3 0.046 13.7 0.3 1.1 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family PAZ_siRNAbind PF12212.8 EJS42880.1 - 0.085 12.7 0.1 0.096 12.5 0.1 1.3 1 0 0 1 1 1 0 PAZ domain Pet191_N PF10203.9 EJS42880.1 - 0.19 12.0 2.3 5.5 7.4 0.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DASH_Ask1 PF08655.10 EJS42881.1 - 2.6e-27 94.5 0.2 4.8e-27 93.6 0.2 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 CPSF73-100_C PF11718.8 EJS42881.1 - 0.047 13.2 0.2 0.08 12.5 0.2 1.5 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term FRG2 PF15315.6 EJS42881.1 - 0.061 13.5 4.1 0.098 12.9 3.6 1.6 1 1 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Frag1 PF10277.9 EJS42882.1 - 1.3e-85 286.4 26.1 1.5e-85 286.2 26.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Eisosome1 PF12757.7 EJS42883.1 - 4.5e-26 91.6 0.3 4.5e-26 91.6 0.3 2.9 3 1 0 3 3 3 1 Eisosome protein 1 Histone PF00125.24 EJS42884.1 - 5.6e-40 136.7 5.6 5.6e-40 136.7 5.6 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EJS42884.1 - 0.0047 17.3 0.1 0.0099 16.2 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EJS42884.1 - 0.0057 16.8 2.0 0.01 16.0 0.2 2.1 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Borrelia_REV PF03978.13 EJS42884.1 - 0.083 12.8 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DUF2347 PF09804.9 EJS42885.1 - 1.9e-78 263.9 1.0 2.9e-78 263.3 1.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EJS42885.1 - 1.7e-09 38.1 1.3 7.4e-06 26.2 0.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) Avl9 PF09794.9 EJS42885.1 - 2.2e-08 33.2 0.3 5.2e-07 28.7 0.3 2.5 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 EJS42885.1 - 5e-07 29.7 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Glyco_hydro_76 PF03663.14 EJS42886.1 - 4.2e-160 533.2 26.1 4.8e-160 533.0 26.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DNA_primase_lrg PF04104.14 EJS42887.1 - 1.5e-90 303.2 0.1 2.6e-90 302.4 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Cbl_N2 PF02761.14 EJS42887.1 - 0.053 14.2 0.0 6 7.7 0.0 3.2 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain KilA-N PF04383.13 EJS42888.1 - 3.9e-05 23.5 0.2 0.00014 21.7 0.2 2.0 1 1 0 1 1 1 1 KilA-N domain Spc42p PF11544.8 EJS42889.1 - 7.5e-24 83.5 13.2 7.5e-24 83.5 13.2 3.1 2 1 0 2 2 2 1 Spindle pole body component Spc42p DUF4116 PF13475.6 EJS42889.1 - 0.0089 15.7 1.4 0.015 15.1 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) UPF0242 PF06785.11 EJS42889.1 - 0.0098 16.0 5.2 0.0098 16.0 5.2 2.6 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 EJS42889.1 - 0.18 11.7 17.5 2.7 7.9 3.5 4.3 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Snf7 PF03357.21 EJS42890.1 - 2.1e-36 125.1 14.7 2.1e-36 125.1 14.7 1.6 1 1 1 2 2 2 1 Snf7 PAS_7 PF12860.7 EJS42890.1 - 0.0038 17.4 3.3 1.1 9.4 0.1 3.2 1 1 2 3 3 3 2 PAS fold Eno-Rase_FAD_bd PF07055.12 EJS42890.1 - 0.053 13.9 1.8 0.16 12.4 0.3 2.6 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain EMP70 PF02990.16 EJS42890.1 - 0.23 10.1 0.2 0.18 10.4 0.2 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Peptidase_S46 PF10459.9 EJS42890.1 - 2.3 6.8 10.7 2.8 6.5 10.7 1.0 1 0 0 1 1 1 0 Peptidase S46 Zn_clus PF00172.18 EJS42891.1 - 9.2e-10 38.5 13.0 1.6e-09 37.7 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rep_fac-A_C PF08646.10 EJS42891.1 - 0.27 10.9 4.2 0.61 9.8 4.2 1.6 1 0 0 1 1 1 0 Replication factor-A C terminal domain UDPGP PF01704.18 EJS42892.1 - 1.3e-184 613.6 0.0 1.6e-184 613.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 EJS42892.1 - 0.0047 15.8 1.0 0.045 12.6 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4301) Arg_decarbox_C PF17944.1 EJS42892.1 - 0.16 12.6 0.1 0.44 11.1 0.1 1.8 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension zf-rbx1 PF12678.7 EJS42893.1 - 5.2e-09 36.3 5.9 8.7e-09 35.5 5.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EJS42893.1 - 6.5e-08 32.8 9.3 1.7e-07 31.4 9.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJS42893.1 - 5.9e-07 29.2 3.5 5.9e-07 29.2 3.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJS42893.1 - 9e-06 25.6 4.5 1.5e-05 24.9 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EJS42893.1 - 3.4e-05 23.6 6.8 6.8e-05 22.7 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJS42893.1 - 4.7e-05 23.3 1.3 4.7e-05 23.3 1.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EJS42893.1 - 0.00028 20.7 5.2 0.00051 19.8 5.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EJS42893.1 - 0.00047 19.7 4.1 0.0012 18.4 4.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EJS42893.1 - 0.00074 19.2 8.4 0.0046 16.7 1.9 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_3 PF13920.6 EJS42893.1 - 0.0011 18.8 5.9 0.0028 17.5 5.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EJS42893.1 - 0.0011 18.9 1.5 0.0023 18.0 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EJS42893.1 - 0.034 14.3 4.5 0.1 12.8 4.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EJS42893.1 - 2.7 8.2 7.4 0.54 10.4 3.5 1.8 2 0 0 2 2 2 0 RING-variant domain zf-P11 PF03854.14 EJS42893.1 - 2.8 7.7 6.7 0.89 9.3 3.4 1.8 2 0 0 2 2 2 0 P-11 zinc finger HAD_2 PF13419.6 EJS42894.1 - 9.1e-26 91.0 0.0 1.4e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJS42894.1 - 3.8e-14 53.5 0.0 5.3e-10 39.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EJS42894.1 - 0.00028 20.9 0.0 0.088 12.9 0.0 2.6 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EJS42894.1 - 0.071 13.5 0.0 0.25 11.7 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase YonK PF09642.10 EJS42894.1 - 0.2 11.8 1.0 3.9 7.7 0.1 2.6 3 0 0 3 3 3 0 YonK protein HMG_box PF00505.19 EJS42895.1 - 7.9e-34 115.9 8.3 1.2e-17 64.0 2.0 3.4 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EJS42895.1 - 2e-15 57.1 4.5 4e-10 40.1 1.5 3.9 3 1 0 3 3 3 2 HMG-box domain CHDNT PF08073.12 EJS42895.1 - 3e-09 36.7 0.0 0.001 19.0 0.0 2.7 2 0 0 2 2 2 2 CHDNT (NUC034) domain SUIM_assoc PF16619.5 EJS42895.1 - 0.0078 16.3 0.3 0.0078 16.3 0.3 9.3 4 2 1 5 5 5 1 Unstructured region C-term to UIM in Ataxin3 Malic_M PF03949.15 EJS42896.1 - 7.3e-85 284.3 0.0 9.8e-85 283.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EJS42896.1 - 2.8e-63 213.0 0.1 9.6e-63 211.3 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain ThiF PF00899.21 EJS42897.1 - 4.1e-40 137.7 0.0 6.4e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EJS42897.1 - 8.6e-05 22.8 0.6 0.0032 17.7 0.6 2.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EJS42897.1 - 0.0007 19.7 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EJS42897.1 - 0.0043 17.3 0.2 0.011 16.0 0.1 1.7 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 EJS42897.1 - 0.012 16.1 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EJS42897.1 - 0.032 13.8 0.1 0.07 12.7 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EJS42897.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pan3_PK PF18101.1 EJS42898.1 - 1.7e-52 177.0 0.4 2.7e-52 176.4 0.4 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain HIGH_NTase1 PF05636.11 EJS42898.1 - 0.045 13.0 0.1 0.072 12.3 0.1 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase ADK PF00406.22 EJS42899.1 - 1.8e-49 167.7 0.0 2.3e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EJS42899.1 - 4.5e-37 127.5 0.0 7.2e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EJS42899.1 - 4.1e-09 37.1 0.0 6.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EJS42899.1 - 2.6e-06 27.7 0.0 5.9e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EJS42899.1 - 3e-06 27.0 0.2 0.046 13.4 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.12 EJS42899.1 - 0.0012 18.2 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 EJS42899.1 - 0.13 12.6 0.2 0.63 10.5 0.1 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) CPSase_L_D3 PF02787.19 EJS42899.1 - 0.15 12.5 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain PPTA PF01239.22 EJS42900.1 - 3.2e-39 131.5 13.7 8.4e-08 31.7 0.8 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF1748 PF08520.10 EJS42901.1 - 5.7e-13 48.6 0.2 7.2e-13 48.2 0.2 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WD40 PF00400.32 EJS42902.1 - 2.4e-16 59.8 0.3 0.00019 22.1 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS42902.1 - 2.3e-09 37.4 0.0 0.00093 19.5 0.0 4.1 2 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_12 PF13087.6 EJS42903.1 - 1e-57 195.0 0.0 1e-57 195.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EJS42903.1 - 2.2e-54 185.0 3.0 5.9e-54 183.6 0.3 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EJS42903.1 - 1.3e-12 48.0 0.2 0.002 17.9 0.0 3.6 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EJS42903.1 - 3.6e-12 46.8 0.0 2.1e-11 44.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EJS42903.1 - 4.5e-11 42.8 0.0 1.9e-09 37.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EJS42903.1 - 3.6e-08 33.6 0.0 3.2e-07 30.5 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EJS42903.1 - 3.9e-07 29.7 0.0 0.00013 21.4 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 EJS42903.1 - 3.2e-05 23.8 0.6 0.00022 21.1 0.6 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 EJS42903.1 - 0.00012 21.7 0.6 0.00012 21.7 0.6 3.3 3 1 1 4 4 4 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EJS42903.1 - 0.00013 22.3 0.0 0.001 19.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EJS42903.1 - 0.0014 19.1 0.3 0.0014 19.1 0.3 3.5 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.6 EJS42903.1 - 0.002 18.2 0.5 0.46 10.5 0.0 3.1 3 1 0 3 3 2 1 AAA domain UvrD_C_2 PF13538.6 EJS42903.1 - 0.0023 17.7 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 EJS42903.1 - 0.0033 17.3 0.0 0.015 15.2 0.0 2.3 2 1 0 2 2 2 1 Helicase DUF2075 PF09848.9 EJS42903.1 - 0.0033 16.7 4.8 0.012 14.9 1.3 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Adeno_IVa2 PF02456.15 EJS42903.1 - 0.0048 15.8 0.3 0.01 14.7 0.3 1.6 1 1 0 1 1 1 1 Adenovirus IVa2 protein AAA_25 PF13481.6 EJS42903.1 - 0.0087 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EJS42903.1 - 0.018 15.4 0.1 0.06 13.8 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJS42903.1 - 0.027 14.9 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EJS42903.1 - 0.03 14.5 0.0 0.085 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 EJS42903.1 - 0.035 14.5 0.2 0.25 11.8 0.0 2.6 3 0 0 3 3 2 0 RNA helicase T2SSE PF00437.20 EJS42903.1 - 0.039 13.0 0.0 0.079 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein HeLo PF14479.6 EJS42903.1 - 0.047 13.5 0.3 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Prion-inhibition and propagation Zot PF05707.12 EJS42903.1 - 0.053 13.2 0.0 0.84 9.3 0.0 2.3 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) FtsK_SpoIIIE PF01580.18 EJS42903.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EJS42903.1 - 0.13 12.0 1.5 2.5 7.8 1.5 2.7 1 1 0 1 1 1 0 AAA domain GTP_EFTU_D2 PF03144.25 EJS42903.1 - 0.25 11.7 1.2 1.4 9.4 0.2 2.7 3 0 0 3 3 2 0 Elongation factor Tu domain 2 Mt_ATP-synt_D PF05873.12 EJS42904.1 - 7.5e-19 68.1 5.0 9.9e-19 67.7 5.0 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) CEP19 PF14933.6 EJS42904.1 - 0.012 15.9 3.5 0.015 15.6 3.5 1.1 1 0 0 1 1 1 0 CEP19-like protein T5orf172 PF10544.9 EJS42904.1 - 0.085 13.4 0.5 0.15 12.6 0.5 1.6 1 1 0 1 1 1 0 T5orf172 domain SRI PF08236.11 EJS42904.1 - 0.17 12.1 3.6 3.7 7.8 0.4 2.4 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain FlxA PF14282.6 EJS42904.1 - 6 6.9 9.2 4.7 7.2 2.4 2.2 1 1 1 2 2 2 0 FlxA-like protein Fungal_trans PF04082.18 EJS42905.1 - 2.3e-17 62.9 2.6 2.3e-17 62.9 2.6 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS42905.1 - 7.1e-10 38.8 7.3 1.2e-09 38.1 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Npa1 PF11707.8 EJS42906.1 - 3e-93 312.9 8.8 3e-93 312.9 8.8 2.6 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EJS42906.1 - 1.1e-47 162.2 0.1 1.1e-47 162.2 0.1 4.4 4 1 1 5 5 5 1 Nucleolar pre-ribosomal-associated protein 1 Thg1 PF04446.12 EJS42906.1 - 0.016 15.2 1.7 0.036 14.1 0.2 2.3 2 0 0 2 2 2 0 tRNAHis guanylyltransferase DUF2184 PF09950.9 EJS42906.1 - 0.029 13.7 0.2 0.065 12.6 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) V-ATPase_H_C PF11698.8 EJS42906.1 - 0.14 12.2 3.0 0.36 11.0 1.0 2.9 2 0 0 2 2 2 0 V-ATPase subunit H ARPC4 PF05856.12 EJS42907.1 - 1.2e-72 243.0 4.1 1.3e-72 242.8 4.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FF PF01846.19 EJS42908.1 - 2.9e-39 133.0 31.7 7.4e-13 48.5 1.3 7.3 9 0 0 9 9 9 4 FF domain WW PF00397.26 EJS42908.1 - 4.4e-19 68.2 13.0 6.3e-11 42.2 1.4 2.8 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 EJS42908.1 - 0.0017 18.7 7.5 0.3 11.4 0.3 3.2 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain CARD PF00619.21 EJS42908.1 - 0.049 13.7 0.8 3.4 7.7 0.1 3.6 3 0 0 3 3 3 0 Caspase recruitment domain SATase_N PF06426.14 EJS42908.1 - 0.41 11.1 6.5 4.5 7.7 0.3 3.5 3 1 1 4 4 4 0 Serine acetyltransferase, N-terminal Ydc2-catalyt PF09159.10 EJS42909.1 - 6.5e-51 173.7 4.2 9.8e-51 173.1 4.2 1.3 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 EJS42909.1 - 0.00045 20.4 0.1 0.44 10.7 0.0 2.7 2 1 0 2 2 2 2 Poxvirus A22 protein HECT PF00632.25 EJS42910.1 - 1.8e-69 234.6 0.1 3.1e-69 233.8 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Rep_fac-A_3 PF08661.11 EJS42910.1 - 0.03 14.6 0.0 2.1 8.8 0.0 3.0 2 0 0 2 2 2 0 Replication factor A protein 3 Ribosomal_L10 PF00466.20 EJS42911.1 - 1.3e-20 73.3 0.0 2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 EJS42911.1 - 3.2e-16 59.1 0.0 5.3e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P TRAM_LAG1_CLN8 PF03798.16 EJS42912.1 - 2e-36 125.6 26.5 2e-36 125.6 26.5 2.2 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EJS42912.1 - 1.1e-22 79.4 1.6 1.1e-22 79.4 1.6 2.1 2 0 0 2 2 2 1 TRAM1-like protein F-actin_cap_A PF01267.17 EJS42913.1 - 1.1e-79 267.7 0.4 1.2e-79 267.5 0.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CdiI_2 PF18593.1 EJS42913.1 - 0.024 15.3 0.1 0.094 13.4 0.0 2.0 2 0 0 2 2 2 0 CdiI immunity protein PAP2_3 PF14378.6 EJS42914.1 - 4.9e-24 85.1 11.3 4.9e-24 85.1 11.3 1.8 2 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EJS42914.1 - 1.6e-10 40.9 6.1 1.6e-10 40.9 6.1 2.3 2 1 0 2 2 2 1 PAP2 superfamily Ribosomal_S6 PF01250.17 EJS42915.1 - 5.8e-24 84.2 0.1 7.6e-24 83.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 APS_kinase PF01583.20 EJS42916.1 - 4.4e-75 250.9 0.0 5.3e-75 250.6 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EJS42916.1 - 1.7e-06 28.3 0.0 4.4e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EJS42916.1 - 0.00023 20.7 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EJS42916.1 - 0.00046 20.7 0.0 0.00075 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EJS42916.1 - 0.00066 19.4 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain CPT PF07931.12 EJS42916.1 - 0.0063 16.4 0.3 0.31 10.9 0.3 2.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein CbiA PF01656.23 EJS42916.1 - 0.036 14.1 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 EJS42916.1 - 0.039 13.2 0.0 0.12 11.7 0.0 1.7 1 1 1 2 2 2 0 Zeta toxin AAA_16 PF13191.6 EJS42916.1 - 0.043 14.2 0.0 0.044 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 EJS42916.1 - 0.086 12.0 0.1 0.15 11.2 0.1 1.3 1 1 0 1 1 1 0 G-protein alpha subunit PRK PF00485.18 EJS42916.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 EJS42916.1 - 0.1 13.1 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Dynamin_M PF01031.20 EJS42917.1 - 3.5e-102 341.5 0.6 7.5e-102 340.4 0.1 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EJS42917.1 - 2.5e-58 196.8 0.2 8.1e-58 195.2 0.2 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EJS42917.1 - 3.8e-28 97.5 5.5 9.9e-28 96.1 5.5 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EJS42917.1 - 0.00062 19.8 1.2 0.0029 17.7 1.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EJS42917.1 - 0.14 12.6 0.4 1.3 9.6 0.1 2.5 2 1 1 3 3 3 0 ABC transporter PAP_central PF04928.17 EJS42918.1 - 7.8e-110 365.7 0.0 3.9e-109 363.4 0.0 1.8 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EJS42918.1 - 5e-51 172.7 0.3 5e-51 172.7 0.3 1.7 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EJS42918.1 - 1.2e-14 54.4 0.0 4.1e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EJS42918.1 - 0.02 15.0 0.2 0.13 12.4 0.0 2.4 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Ribosomal_L50 PF10501.9 EJS42920.1 - 1.5e-17 63.7 0.5 1.5e-17 63.7 0.5 1.8 2 0 0 2 2 2 1 Ribosomal subunit 39S DUF3520 PF12034.8 EJS42920.1 - 0.024 14.8 0.1 0.053 13.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3520) CRA PF06589.11 EJS42920.1 - 0.67 10.1 4.5 0.32 11.1 1.0 2.1 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) LAMTOR PF15454.6 EJS42921.1 - 5.8e-21 74.9 3.3 5.8e-21 74.9 3.3 2.0 2 1 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Bromodomain PF00439.25 EJS42922.1 - 1.4e-29 101.9 7.5 2.2e-19 69.3 0.5 2.8 2 0 0 2 2 2 2 Bromodomain CHIP_TPR_N PF18391.1 EJS42922.1 - 2.6 8.9 6.5 6.8 7.5 1.1 3.3 3 0 0 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain adh_short PF00106.25 EJS42923.1 - 2.4e-84 281.7 8.4 6.4e-43 146.5 0.3 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EJS42923.1 - 3e-67 226.6 2.7 3.5e-35 121.7 0.1 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EJS42923.1 - 8.6e-36 122.2 0.0 1.7e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EJS42923.1 - 8.2e-34 117.1 2.2 1.8e-16 60.6 0.0 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 EJS42923.1 - 0.011 15.9 0.0 0.67 10.1 0.0 2.6 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase PglL_A PF15864.5 EJS42923.1 - 2.1 8.1 8.0 5.4 6.8 1.0 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase 3HCDH_N PF02737.18 EJS42923.1 - 2.8 7.8 5.9 5.2 6.9 0.0 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ERM PF00769.19 EJS42924.1 - 0.012 15.5 0.1 0.012 15.5 0.1 2.0 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Ndr PF03096.14 EJS42924.1 - 0.1 11.3 1.2 0.17 10.5 1.2 1.4 1 0 0 1 1 1 0 Ndr family CAP PF00188.26 EJS42925.1 - 4.7e-15 56.5 2.4 1.4e-14 55.0 2.4 1.8 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF3306 PF11748.8 EJS42925.1 - 0.38 11.6 11.0 3.6 8.5 11.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) Ras PF00071.22 EJS42926.1 - 4.1e-54 182.6 0.1 5.4e-54 182.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS42926.1 - 3.4e-35 120.9 0.0 5.3e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS42926.1 - 2.9e-12 46.4 0.1 5.7e-12 45.4 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EJS42926.1 - 2.6e-05 24.3 0.0 4.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJS42926.1 - 0.00018 21.1 0.1 0.00029 20.4 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EJS42926.1 - 0.00078 18.9 0.0 0.0013 18.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EJS42926.1 - 0.011 15.6 0.3 0.84 9.5 0.0 2.8 2 1 0 2 2 2 0 RsgA GTPase Raptor_N PF14538.6 EJS42926.1 - 0.028 14.4 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain TniB PF05621.11 EJS42926.1 - 0.041 13.3 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 EJS42926.1 - 0.08 13.3 0.1 0.12 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF3808 PF10300.9 EJS42928.1 - 2e-180 600.6 0.6 2.4e-180 600.4 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.6 EJS42928.1 - 0.0075 16.9 2.7 1.7 9.4 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EJS42928.1 - 0.14 12.3 2.6 20 5.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EJS42928.1 - 1.5 9.4 12.8 1.2 9.7 0.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EJS42928.1 - 6.3 7.7 6.5 14 6.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_4 PF12763.7 EJS42929.1 - 0.005 16.8 0.0 0.023 14.6 0.0 2.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Vps51 PF08700.11 EJS42930.1 - 1.3e-11 44.4 3.1 2.5e-11 43.5 2.7 1.7 1 1 0 1 1 1 1 Vps51/Vps67 DUF4050 PF13259.6 EJS42930.1 - 0.0035 17.7 0.5 0.0043 17.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) HBS1_N PF08938.10 EJS42930.1 - 0.02 15.2 3.1 0.043 14.1 3.1 1.8 1 1 0 1 1 1 0 HBS1 N-terminus Histone PF00125.24 EJS42930.1 - 0.052 13.9 1.7 0.072 13.5 0.6 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF2810 PF10928.8 EJS42930.1 - 0.16 12.0 0.2 3.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2810) Arrestin_C PF02752.22 EJS42931.1 - 1e-16 61.6 0.3 2.2e-14 54.1 0.0 2.9 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EJS42931.1 - 1.2e-06 28.6 0.3 0.00024 21.2 0.1 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain NTR2 PF15458.6 EJS42932.1 - 1.3e-143 478.2 22.5 1.5e-143 478.0 22.5 1.0 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DEAD PF00270.29 EJS42933.1 - 4.9e-42 143.7 0.0 8.5e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EJS42933.1 - 1.1e-19 70.4 0.1 3.4e-19 68.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EJS42933.1 - 5.6e-17 62.1 0.0 1.5e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS42933.1 - 1.7e-07 31.4 0.0 3.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3450 PF11932.8 EJS42933.1 - 0.056 12.7 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ERCC3_RAD25_C PF16203.5 EJS42933.1 - 0.091 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase IF-2B PF01008.17 EJS42934.1 - 1.2e-81 274.0 0.0 1.4e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 EJS42934.1 - 0.085 12.8 0.1 6 6.8 0.0 2.5 2 0 0 2 2 2 0 DeoR C terminal sensor domain HisKA PF00512.25 EJS42934.1 - 0.18 11.8 0.2 0.63 10.1 0.1 1.9 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EJS42935.1 - 1.1e-07 32.3 0.0 1.6e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EJS42935.1 - 2.9e-05 24.7 0.0 3.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EJS42935.1 - 0.049 14.0 0.0 0.14 12.5 0.0 1.7 1 1 0 1 1 1 0 GAF domain DBR1 PF05011.13 EJS42937.1 - 1.9e-10 41.3 0.4 9.3e-10 39.1 0.1 2.1 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EJS42937.1 - 5.1e-08 33.7 3.8 5.1e-08 33.7 3.8 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Usg PF06233.12 EJS42937.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Usg-like family FAD_binding_2 PF00890.24 EJS42938.1 - 7.2e-124 414.0 2.3 9.3e-124 413.7 2.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EJS42938.1 - 3.8e-44 149.8 0.8 3.8e-44 149.8 0.8 1.6 2 0 0 2 2 2 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EJS42938.1 - 1.1e-06 28.0 0.5 0.00043 19.5 0.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EJS42938.1 - 1.3e-05 24.5 0.8 3.6e-05 23.1 0.8 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJS42938.1 - 0.00049 19.4 0.3 0.02 14.2 0.1 2.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EJS42938.1 - 0.003 17.2 3.3 0.0094 15.6 3.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EJS42938.1 - 0.0085 15.4 1.6 0.013 14.8 0.1 2.1 3 0 0 3 3 3 1 FAD binding domain BNIP2 PF12496.8 EJS42938.1 - 0.0097 16.4 1.4 0.018 15.5 1.4 1.4 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 HI0933_like PF03486.14 EJS42938.1 - 0.015 14.0 1.2 0.054 12.2 0.2 2.3 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 EJS42938.1 - 0.89 8.8 4.0 5.2 6.2 1.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aa_trans PF01490.18 EJS42939.1 - 3.4e-104 348.8 30.2 4e-104 348.6 30.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA PF00004.29 EJS42940.1 - 4.4e-40 137.1 0.0 7.9e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS42940.1 - 1.1e-06 28.4 0.0 2.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EJS42940.1 - 7.3e-05 22.8 0.0 0.00023 21.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EJS42940.1 - 0.00011 22.5 0.0 0.0029 17.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EJS42940.1 - 0.00023 21.6 0.1 0.0041 17.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EJS42940.1 - 0.00031 20.9 0.0 0.00069 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EJS42940.1 - 0.001 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EJS42940.1 - 0.0033 17.2 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EJS42940.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EJS42940.1 - 0.026 14.2 0.0 0.078 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EJS42940.1 - 0.028 14.6 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EJS42940.1 - 0.029 14.8 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EJS42940.1 - 0.033 14.7 0.0 0.08 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EJS42940.1 - 0.033 13.7 0.0 0.083 12.4 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 EJS42940.1 - 0.05 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EJS42940.1 - 0.054 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EJS42940.1 - 0.056 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 EJS42940.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EJS42940.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_pol_Rbc25 PF08292.12 EJS42941.1 - 6.5e-51 171.9 0.2 8.3e-51 171.6 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EJS42941.1 - 4.8e-20 71.7 0.0 7.5e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 LTV PF04180.14 EJS42942.1 - 4.6e-111 372.2 32.1 5.6e-111 372.0 32.1 1.0 1 0 0 1 1 1 1 Low temperature viability protein DUF3294 PF07957.11 EJS42943.1 - 9.1e-92 306.6 3.7 1e-91 306.5 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Tricorn_C1 PF14684.6 EJS42943.1 - 0.06 13.4 0.1 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 Tricorn protease C1 domain ANAPC2 PF08672.11 EJS42943.1 - 0.077 13.5 0.9 0.27 11.8 0.0 2.4 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 MCPVI PF02993.14 EJS42943.1 - 0.13 12.1 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Minor capsid protein VI ABC_tran_CTD PF16326.5 EJS42943.1 - 7.1 7.0 7.4 3.5 7.9 0.7 3.0 2 1 1 3 3 3 0 ABC transporter C-terminal domain Sdh_cyt PF01127.22 EJS42944.1 - 9.2e-23 80.6 4.2 1.2e-22 80.2 4.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit APC_r PF05923.12 EJS42944.1 - 0.16 11.7 0.7 0.34 10.7 0.7 1.6 1 0 0 1 1 1 0 APC repeat Abhydrolase_1 PF00561.20 EJS42945.1 - 4.2e-42 144.6 0.1 5.6e-42 144.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EJS42945.1 - 8.4e-22 76.5 0.1 1.5e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EJS42945.1 - 0.00029 20.2 0.0 0.033 13.4 0.0 2.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EJS42945.1 - 0.00045 19.9 0.6 0.012 15.3 0.1 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EJS42945.1 - 0.0018 18.1 0.0 0.61 9.9 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Ndr PF03096.14 EJS42945.1 - 0.0018 17.0 0.1 0.12 11.0 0.0 2.2 2 0 0 2 2 2 2 Ndr family L31 PF09784.9 EJS42946.1 - 7e-41 138.8 7.5 2.1e-40 137.3 7.5 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L31 WBS_methylT PF12589.8 EJS42946.1 - 0.3 11.9 7.1 0.61 10.9 7.1 1.7 1 1 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Cmc1 PF08583.10 EJS42947.1 - 1.3e-19 69.9 4.5 1.7e-19 69.6 4.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 EJS42947.1 - 0.0053 16.5 1.8 0.0074 16.0 1.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Acetyltransf_CG PF14542.6 EJS42947.1 - 0.015 15.4 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CHCH PF06747.13 EJS42947.1 - 0.15 12.2 5.0 0.65 10.2 4.7 1.9 1 1 1 2 2 2 0 CHCH domain COX17 PF05051.13 EJS42947.1 - 0.17 12.2 4.1 1.1 9.7 0.2 2.5 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) Adaptin_N PF01602.20 EJS42948.1 - 4.2e-133 444.7 22.5 5.1e-133 444.4 22.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EJS42948.1 - 1.1e-54 184.9 15.1 1.4e-52 178.0 7.1 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EJS42948.1 - 1.2e-10 41.6 1.8 0.00079 19.8 0.1 5.0 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 EJS42948.1 - 3.6e-07 29.9 1.1 0.27 11.6 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat DUF5388 PF17363.2 EJS42948.1 - 0.01 16.1 0.3 0.055 13.7 0.0 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5388) HEAT_EZ PF13513.6 EJS42948.1 - 0.011 16.3 0.6 11 6.7 0.0 4.5 4 1 1 5 5 5 0 HEAT-like repeat Arm PF00514.23 EJS42948.1 - 0.3 11.2 4.9 0.63 10.2 0.5 3.7 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat She2p PF11435.8 EJS42949.1 - 4.5e-90 300.7 4.9 5.4e-90 300.5 4.9 1.1 1 0 0 1 1 1 1 RNA binding protein She2p Myosin_head PF00063.21 EJS42950.1 - 8.5e-228 757.9 10.5 1.1e-227 757.6 10.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EJS42950.1 - 1.3e-45 155.4 0.8 3.6e-45 154.0 0.8 1.9 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EJS42950.1 - 9.3e-11 41.2 0.0 1.8e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJS42950.1 - 1.9e-05 24.4 0.0 4.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJS42950.1 - 0.0026 17.4 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.6 EJS42950.1 - 0.048 13.9 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EJS42950.1 - 0.054 13.9 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 EJS42950.1 - 0.059 12.9 0.2 9.2 5.8 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 EJS42950.1 - 0.06 13.7 0.0 0.48 10.8 0.0 2.7 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 EJS42950.1 - 0.061 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EJS42950.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 EJS42950.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IQ PF00612.27 EJS42950.1 - 8.2 6.5 14.6 17 5.6 1.3 2.9 1 1 1 2 2 2 0 IQ calmodulin-binding motif His_Phos_1 PF00300.22 EJS42951.1 - 4.3e-06 26.6 0.1 0.026 14.2 0.1 3.0 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) PGM_PMM_I PF02878.16 EJS42952.1 - 4.2e-35 120.5 0.4 7.8e-35 119.6 0.1 1.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EJS42952.1 - 9.3e-27 93.5 0.0 1.8e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EJS42952.1 - 3.7e-11 43.5 0.0 7.5e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EJS42952.1 - 2.7e-05 24.2 0.0 6.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.25 EJS42953.1 - 4.2e-67 226.3 0.0 6.1e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42953.1 - 7.3e-31 107.4 0.0 1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EJS42953.1 - 1.5e-11 44.8 0.6 4.6e-11 43.2 0.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EJS42953.1 - 0.00031 19.8 0.0 0.00061 18.8 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EJS42953.1 - 0.0052 16.2 0.0 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EJS42953.1 - 0.012 15.2 0.1 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 FOXO_KIX_bdg PF16675.5 EJS42953.1 - 0.025 14.9 0.0 0.08 13.3 0.0 1.9 1 0 0 1 1 1 0 KIX-binding domain of forkhead box O, CR2 Kdo PF06293.14 EJS42953.1 - 0.044 13.1 0.3 0.091 12.1 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJS42953.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRN3 PF05327.11 EJS42954.1 - 9.7e-185 615.3 7.2 1.2e-184 615.0 7.2 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EJS42954.1 - 0.0009 17.6 0.7 0.0016 16.8 0.7 1.4 1 0 0 1 1 1 1 Nop14-like family IFT57 PF10498.9 EJS42954.1 - 0.037 13.0 3.2 0.077 12.0 3.2 1.6 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 WD40 PF00400.32 EJS42955.1 - 7.8e-12 45.5 12.1 0.0043 17.9 0.1 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS42955.1 - 0.00012 22.3 0.0 2 8.8 0.0 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJS42955.1 - 0.0014 17.4 0.4 0.048 12.3 0.0 2.7 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EJS42955.1 - 0.15 11.0 0.0 0.94 8.4 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mito_carr PF00153.27 EJS42956.1 - 1.2e-54 182.2 6.6 1.1e-17 63.7 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EJS42956.1 - 0.007 16.6 0.1 0.72 10.1 0.1 2.8 3 0 0 3 3 3 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Vma12 PF11712.8 EJS42957.1 - 4.6e-37 127.2 1.3 7.6e-37 126.5 1.3 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3169 PF11368.8 EJS42957.1 - 0.0083 15.7 1.0 0.012 15.1 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) MscS_TM PF12794.7 EJS42957.1 - 0.065 12.1 0.8 0.092 11.6 0.2 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 LapA_dom PF06305.11 EJS42957.1 - 0.075 12.9 0.4 0.44 10.4 0.2 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MMgT PF10270.9 EJS42957.1 - 0.094 13.1 0.2 0.32 11.4 0.1 2.0 1 1 0 1 1 1 0 Membrane magnesium transporter DUF1461 PF07314.11 EJS42957.1 - 0.11 12.4 0.3 0.11 12.4 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1461) XPG_N PF00752.17 EJS42958.1 - 7.5e-40 135.5 0.0 1.7e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EJS42958.1 - 6.1e-29 100.2 0.0 6.1e-29 100.2 0.0 2.0 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 EJS42958.1 - 2.3e-05 24.9 1.1 0.00012 22.6 0.0 2.6 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EJS42958.1 - 0.011 16.4 0.0 0.036 14.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain 5_3_exonuc_N PF02739.16 EJS42958.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.6 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain HHH_2 PF12826.7 EJS42958.1 - 0.018 15.1 0.1 0.061 13.4 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF2229 PF09989.9 EJS42958.1 - 0.029 14.0 1.1 0.44 10.2 0.1 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) CDKN3 PF05706.12 EJS42958.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) MRPL52 PF18699.1 EJS42958.1 - 2.3 8.5 9.6 0.17 12.1 0.6 2.6 2 0 0 2 2 2 0 Mitoribosomal protein mL52 BAF1_ABF1 PF04684.13 EJS42959.1 - 3.7e-190 633.7 90.2 1e-187 625.6 90.2 2.1 1 1 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.15 EJS42959.1 - 0.004 17.1 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 MuDR family transposase KTI12 PF08433.10 EJS42960.1 - 2.8e-97 325.4 0.0 3.2e-97 325.2 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EJS42960.1 - 9.2e-05 22.6 0.0 0.00026 21.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EJS42960.1 - 0.00031 21.3 0.0 0.00064 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EJS42960.1 - 0.0049 16.8 0.0 0.0083 16.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.6 EJS42960.1 - 0.0085 16.5 0.0 0.048 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EJS42960.1 - 0.014 14.9 0.1 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EJS42960.1 - 0.043 14.1 0.0 0.16 12.2 0.0 2.0 3 0 0 3 3 3 0 AAA domain 6PF2K PF01591.18 EJS42960.1 - 0.055 12.8 1.0 0.52 9.6 0.0 2.4 2 1 0 2 2 2 0 6-phosphofructo-2-kinase AAA_16 PF13191.6 EJS42960.1 - 0.065 13.6 0.1 0.13 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EJS42960.1 - 0.077 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EJS42960.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hap4_Hap_bind PF10297.9 EJS42961.1 - 6.9e-07 29.2 5.9 6.9e-07 29.2 5.9 2.1 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Drc1-Sld2 PF11719.8 EJS42962.1 - 1.5e-44 153.4 26.2 2.1e-27 96.8 14.1 2.1 1 1 1 2 2 2 2 DNA replication and checkpoint protein LRAT PF04970.13 EJS42962.1 - 0.0017 18.6 0.8 0.0042 17.4 0.1 2.0 2 0 0 2 2 2 1 Lecithin retinol acyltransferase Imm-NTF2 PF15655.6 EJS42962.1 - 0.088 13.1 1.5 0.21 11.9 1.5 1.6 1 0 0 1 1 1 0 NTF2 fold immunity protein Aminotran_1_2 PF00155.21 EJS42963.1 - 5.3e-100 335.1 0.0 6e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SIS PF01380.22 EJS42964.1 - 1.2e-67 225.7 0.1 1.6e-33 115.3 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EJS42964.1 - 7.5e-17 61.8 0.0 1.6e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EJS42964.1 - 3.4e-10 39.9 0.0 7.1e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EJS42964.1 - 1.4e-05 24.2 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 EJS42964.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 SIS domain Peptidase_M18 PF02127.15 EJS42965.1 - 1.2e-160 535.0 0.0 1.5e-160 534.7 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Pkinase PF00069.25 EJS42966.1 - 2.5e-70 236.9 0.2 6.2e-64 215.9 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJS42966.1 - 1.9e-34 119.1 0.0 5e-33 114.5 0.0 2.3 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EJS42966.1 - 0.0019 17.6 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1199 PF06712.11 EJS42966.1 - 0.0021 18.0 1.6 0.018 15.1 1.6 2.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1199) Choline_kinase PF01633.20 EJS42966.1 - 0.0099 15.5 0.0 0.0099 15.5 0.0 3.6 4 0 0 4 4 4 1 Choline/ethanolamine kinase APH PF01636.23 EJS42966.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_A22B PF04258.13 EJS42967.1 - 4.5e-102 341.4 14.0 7.4e-102 340.7 14.0 1.3 1 0 0 1 1 1 1 Signal peptide peptidase RHH_7 PF16777.5 EJS42968.1 - 0.17 12.3 0.4 0.5 10.8 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator, RHH-like, CopG PIR PF00399.19 EJS42969.1 - 1.9e-08 33.6 9.9 1.9e-08 33.6 9.9 3.4 2 1 1 3 3 3 1 Yeast PIR protein repeat Shisa PF13908.6 EJS42969.1 - 0.14 12.4 2.5 0.16 12.2 2.5 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PIR PF00399.19 EJS42970.1 - 2.5e-07 30.1 3.1 8.8e-07 28.3 3.1 2.1 1 0 0 1 1 1 1 Yeast PIR protein repeat DUF1189 PF06691.11 EJS42970.1 - 0.13 11.9 0.1 0.19 11.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) Apt1 PF10351.9 EJS42970.1 - 5.3 5.8 9.1 6.3 5.5 9.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.13 EJS42971.1 - 2.9e-45 155.3 18.5 7.8e-45 153.9 18.5 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF572) Mut7-C PF01927.16 EJS42971.1 - 0.018 15.1 0.2 0.018 15.1 0.2 2.2 2 1 0 2 2 2 0 Mut7-C RNAse domain Iron_permease PF04120.12 EJS42971.1 - 0.07 12.9 3.0 0.17 11.7 3.0 1.6 1 0 0 1 1 1 0 Low affinity iron permease DUF4291 PF14124.6 EJS42971.1 - 0.12 12.2 5.1 0.2 11.5 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) zf_UBZ PF18439.1 EJS42971.1 - 0.26 10.9 1.7 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Cytochrom_C552 PF02335.15 EJS42971.1 - 0.69 8.8 6.4 0.41 9.5 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c552 E7 PF00527.18 EJS42971.1 - 1.8 8.8 0.0 1.8 8.8 0.0 2.9 2 1 0 2 2 1 0 E7 protein, Early protein RRN3 PF05327.11 EJS42971.1 - 1.8 7.0 12.6 2.5 6.6 12.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TadF PF16964.5 EJS42971.1 - 3.9 7.2 10.3 0.85 9.3 5.3 1.9 2 0 0 2 2 2 0 Putative tight adherence pilin protein F DUF4407 PF14362.6 EJS42971.1 - 4.1 6.7 5.9 6.5 6.0 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EJS42971.1 - 9.1 6.3 12.7 1.8 8.6 9.2 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MBR1 PF17058.5 EJS42972.1 - 2.6e-57 194.5 9.2 2.6e-57 194.5 9.2 1.8 2 0 0 2 2 2 1 Mitochondrial biogenesis regulation protein 1 MMTV_SAg PF01054.17 EJS42972.1 - 0.097 12.2 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen CRAL_TRIO PF00650.20 EJS42973.1 - 4.7e-34 117.4 0.2 6.9e-34 116.9 0.2 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJS42973.1 - 2.5e-08 34.0 0.1 6.2e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EJS42973.1 - 3.4e-06 27.2 0.1 5.8e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CUE PF02845.16 EJS42974.1 - 6e-19 67.4 1.8 2.5e-09 36.7 0.1 3.2 3 0 0 3 3 3 2 CUE domain Smr PF01713.21 EJS42974.1 - 0.0042 17.4 0.0 0.0095 16.3 0.0 1.6 1 0 0 1 1 1 1 Smr domain DMA PF03474.14 EJS42974.1 - 0.18 11.4 0.2 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 DMRTA motif CENP-C_C PF11699.8 EJS42975.1 - 1.2e-31 108.7 1.6 2.5e-31 107.7 1.6 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 EJS42975.1 - 1.1e-05 26.1 7.1 1.1e-05 26.1 7.1 3.1 2 2 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 EJS42975.1 - 0.0048 16.6 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AT_hook PF02178.19 EJS42975.1 - 0.13 12.2 5.4 0.39 10.8 5.4 1.9 1 0 0 1 1 1 0 AT hook motif TarS_C1 PF18674.1 EJS42975.1 - 0.77 9.7 5.1 0.32 10.9 0.1 2.6 3 0 0 3 3 3 0 TarS beta-glycosyltransferase C-terminal domain 1 Cyto_heme_lyase PF01265.17 EJS42976.1 - 8.1e-38 130.7 11.6 2.5e-36 125.8 11.6 2.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase ParBc PF02195.18 EJS42977.1 - 1.2e-23 83.2 0.0 1.4e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Ldh_1_C PF02866.18 EJS42978.1 - 1.5e-56 190.9 0.0 3.6e-56 189.7 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EJS42978.1 - 3.9e-44 150.2 0.1 6.2e-44 149.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EJS42978.1 - 0.00033 19.7 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family zf-CHY PF05495.12 EJS42979.1 - 5.3e-13 49.3 12.4 8.1e-13 48.7 12.4 1.3 1 0 0 1 1 1 1 CHY zinc finger zf-RING_4 PF14570.6 EJS42979.1 - 6.5e-05 22.6 0.4 6.5e-05 22.6 0.4 2.9 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain A2L_zn_ribbon PF08792.10 EJS42979.1 - 0.0046 16.6 2.8 0.0046 16.6 2.8 2.4 2 1 0 2 2 2 1 A2L zinc ribbon domain Zn_ribbon_recom PF13408.6 EJS42979.1 - 0.013 16.0 3.0 0.013 16.0 3.0 2.8 2 2 0 2 2 2 0 Recombinase zinc beta ribbon domain DZR PF12773.7 EJS42979.1 - 0.025 14.6 9.1 0.32 11.0 9.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 EJS42979.1 - 0.035 14.2 6.3 1.7 8.8 0.8 2.6 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Tmemb_55A PF09788.9 EJS42979.1 - 0.052 12.6 4.9 0.057 12.5 4.9 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A Zn-ribbon_8 PF09723.10 EJS42979.1 - 0.055 13.6 1.1 0.055 13.6 1.1 2.5 1 1 1 2 2 2 0 Zinc ribbon domain Trm112p PF03966.16 EJS42979.1 - 0.059 13.9 3.6 0.22 12.1 3.6 2.2 1 1 0 1 1 1 0 Trm112p-like protein DUF2318 PF10080.9 EJS42979.1 - 0.074 13.2 0.8 0.074 13.2 0.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) HypA PF01155.19 EJS42979.1 - 0.087 12.9 5.8 0.29 11.2 5.8 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_3 PF13920.6 EJS42979.1 - 0.23 11.3 11.9 0.2 11.5 0.9 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.12 EJS42979.1 - 0.28 10.7 8.7 0.28 10.7 5.4 2.4 1 1 1 2 2 2 0 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 EJS42979.1 - 0.3 11.4 9.5 1.3 9.3 3.0 2.6 1 1 1 2 2 2 0 zinc-ribbon PhnA_Zn_Ribbon PF08274.12 EJS42979.1 - 0.31 11.0 10.3 0.68 9.9 0.2 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon IBR PF01485.21 EJS42979.1 - 8.7 6.7 17.4 2e+03 -0.9 17.4 2.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain SURF6 PF04935.12 EJS42980.1 - 2e-48 164.9 45.9 2e-48 164.9 45.9 3.2 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 EJS42980.1 - 2.7e-12 47.1 2.6 2.7e-12 47.1 2.6 7.5 5 3 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 V-ATPase_C PF03223.15 EJS42981.1 - 2.3e-120 402.4 1.1 2.6e-120 402.3 1.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NUC130_3NT PF08158.12 EJS42981.1 - 0.0052 17.1 0.1 6 7.3 0.1 2.6 2 0 0 2 2 2 2 NUC130/3NT domain LMBR1 PF04791.16 EJS42981.1 - 0.082 11.8 0.6 0.1 11.5 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HA2 PF04408.23 EJS42982.1 - 8.1e-20 71.1 0.0 1.7e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EJS42982.1 - 4.3e-14 52.6 0.0 1.2e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EJS42982.1 - 1.8e-09 37.6 0.2 3.2e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS42982.1 - 1.8e-08 34.7 0.0 5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EJS42982.1 - 2.9e-06 27.6 0.1 6.5e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJS42982.1 - 0.00011 22.6 0.1 0.00019 21.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJS42982.1 - 0.00016 21.5 0.2 0.00074 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EJS42982.1 - 0.0021 18.6 0.2 0.1 13.1 0.1 2.8 2 1 1 3 3 3 1 ABC transporter AAA_14 PF13173.6 EJS42982.1 - 0.0098 15.9 0.1 0.22 11.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EJS42982.1 - 0.013 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Helicase SRP54 PF00448.22 EJS42982.1 - 0.017 14.7 0.2 0.092 12.4 0.2 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EJS42982.1 - 0.017 14.8 0.6 0.035 13.8 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EJS42982.1 - 0.022 15.3 0.9 0.039 14.4 0.1 1.8 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EJS42982.1 - 0.068 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EJS42982.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 EJS42982.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain HSP70 PF00012.20 EJS42984.1 - 1.8e-51 175.1 1.9 1.8e-51 175.1 1.9 2.0 2 1 1 3 3 3 1 Hsp70 protein Swi3 PF07962.12 EJS42984.1 - 0.044 13.8 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 DUF1189 PF06691.11 EJS42984.1 - 1.4 8.4 5.5 0.22 11.1 0.7 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1189) Methyltransf_28 PF02636.17 EJS42985.1 - 4.1e-16 59.4 0.0 5.5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Elf1 PF05129.13 EJS42986.1 - 2.6e-31 107.5 2.8 3.4e-31 107.1 2.8 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Mpp10 PF04006.12 EJS42986.1 - 0.033 12.6 7.9 0.048 12.1 7.9 1.2 1 0 0 1 1 1 0 Mpp10 protein NOA36 PF06524.12 EJS42986.1 - 0.093 12.0 10.4 0.13 11.5 10.4 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EJS42986.1 - 0.097 10.8 8.7 0.082 11.0 8.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L37ae PF01780.19 EJS42986.1 - 0.12 12.4 1.5 0.21 11.7 1.5 1.3 1 0 0 1 1 1 0 Ribosomal L37ae protein family GCIP PF13324.6 EJS42986.1 - 0.22 11.1 5.0 0.29 10.7 5.0 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 EJS42986.1 - 0.29 9.3 7.3 0.24 9.6 7.3 1.2 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 EJS42986.1 - 0.36 8.9 5.9 0.4 8.7 5.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 EJS42986.1 - 2.9 6.1 9.6 3.6 5.8 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Rsm22 PF09243.10 EJS42987.1 - 1.9e-29 102.8 0.3 6.3e-10 38.8 0.1 4.3 3 1 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 EJS42987.1 - 1.4e-05 25.0 0.0 3.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain VWA_N PF08399.11 EJS42987.1 - 0.11 13.0 0.3 0.11 13.0 0.3 2.7 3 0 0 3 3 3 0 VWA N-terminal SRPRB PF09439.10 EJS42988.1 - 8.8e-68 227.3 0.2 1.5e-67 226.6 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EJS42988.1 - 9e-11 41.5 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EJS42988.1 - 2.5e-06 27.5 0.2 6.7e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJS42988.1 - 0.001 18.6 0.1 0.0018 17.8 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_15 PF13175.6 EJS42988.1 - 0.0024 17.7 3.7 0.52 10.0 0.1 2.1 2 0 0 2 2 2 2 AAA ATPase domain DUF2570 PF10828.8 EJS42988.1 - 0.02 14.7 0.3 0.034 14.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Dynamin_N PF00350.23 EJS42988.1 - 0.022 14.8 4.1 1.7 8.7 4.1 3.2 1 1 0 1 1 1 0 Dynamin family DUF4974 PF16344.5 EJS42988.1 - 0.036 14.1 0.1 0.12 12.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) AAA_23 PF13476.6 EJS42988.1 - 0.063 13.8 4.9 1.4 9.4 0.4 2.1 2 0 0 2 2 2 0 AAA domain T3SS_basalb_I PF17001.5 EJS42988.1 - 0.077 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI AAA_22 PF13401.6 EJS42988.1 - 0.1 12.9 0.0 2.5 8.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain DUF1870 PF08965.10 EJS42988.1 - 0.17 11.9 0.9 0.42 10.7 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1870) ATPase_2 PF01637.18 EJS42988.1 - 0.21 11.5 4.5 1.3 8.9 0.0 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea His_Phos_1 PF00300.22 EJS42989.1 - 7e-38 130.3 0.0 2e-30 106.0 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Tnp_22_dsRBD PF17490.2 EJS42989.1 - 0.055 13.5 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain Synaptobrevin PF00957.21 EJS42990.1 - 3.2e-15 55.7 1.1 5.1e-15 55.0 1.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EJS42990.1 - 2.4e-12 46.7 0.0 3.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain tRNA-synt_2b PF00587.25 EJS42991.1 - 6.5e-51 172.8 0.0 9.9e-51 172.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EJS42991.1 - 2.4e-19 69.3 0.2 3.8e-19 68.6 0.2 1.3 1 0 0 1 1 1 1 Anticodon binding domain PP-binding PF00550.25 EJS42992.1 - 2.5e-13 50.2 0.2 3.4e-13 49.7 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EJS42992.1 - 3.2e-07 30.5 0.4 4.2e-07 30.1 0.4 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.12 EJS42992.1 - 0.0097 16.4 0.5 0.014 15.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Diphthamide_syn PF01866.17 EJS42993.1 - 2.6e-67 227.4 0.0 6e-67 226.2 0.0 1.6 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Mo25 PF08569.11 EJS42994.1 - 6.6e-113 377.4 9.4 7.6e-113 377.2 9.4 1.0 1 0 0 1 1 1 1 Mo25-like YqbF PF14553.6 EJS42994.1 - 0.13 12.1 0.0 0.78 9.7 0.0 2.2 2 0 0 2 2 2 0 YqbF, hypothetical protein domain GATA PF00320.27 EJS42995.1 - 1.7e-10 40.3 7.8 3.9e-10 39.2 7.8 1.7 1 0 0 1 1 1 1 GATA zinc finger RXT2_N PF08595.11 EJS42995.1 - 0.069 13.2 0.5 0.069 13.2 0.5 2.9 3 0 0 3 3 3 0 RXT2-like, N-terminal DUF1729 PF08354.10 EJS42996.1 - 1.2e-152 507.9 0.0 1.8e-152 507.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EJS42996.1 - 4.3e-115 384.6 0.0 5.7e-114 380.9 0.0 2.8 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 EJS42996.1 - 1.1e-48 164.7 0.0 2.7e-48 163.5 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 EJS42996.1 - 1.8e-41 142.5 0.0 4.9e-41 141.0 0.0 1.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EJS42996.1 - 4.3e-38 129.6 0.0 8.7e-38 128.6 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 EJS42996.1 - 4.5e-38 130.2 0.0 1e-37 129.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 EJS42996.1 - 1.5e-16 60.7 0.0 4.1e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 EJS42996.1 - 0.032 13.6 0.0 0.11 11.9 0.0 1.9 1 0 0 1 1 1 0 Nitronate monooxygenase Pribosyltran_N PF13793.6 EJS42997.1 - 2.7e-40 136.9 0.0 1.1e-39 135.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EJS42997.1 - 1.6e-39 135.8 1.0 8.4e-32 110.7 0.2 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EJS42997.1 - 1.1e-07 31.5 0.1 0.00019 21.0 0.1 2.2 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Zip PF02535.22 EJS42998.1 - 6.4e-23 81.5 16.5 1.4e-21 77.1 16.5 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3899 PF13038.6 EJS42998.1 - 0.24 11.9 0.0 0.24 11.9 0.0 3.1 3 2 0 3 3 3 0 Domain of unknown function (DUF3899) Virul_fac_BrkB PF03631.15 EJS42998.1 - 2.9 7.4 8.1 0.16 11.6 1.6 2.0 2 1 1 3 3 3 0 Virulence factor BrkB AA_permease PF00324.21 EJS42999.1 - 3.8e-100 335.8 44.8 4.7e-100 335.5 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS42999.1 - 2e-34 119.1 48.1 2.7e-34 118.8 48.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3810 PF12725.7 EJS42999.1 - 0.054 12.8 0.1 0.054 12.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Ebp2 PF05890.12 EJS43000.1 - 6.2e-85 285.0 26.5 6.2e-85 285.0 26.5 2.5 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 Ribosomal_L14 PF00238.19 EJS43001.1 - 2.1e-38 131.1 3.4 2.3e-38 131.0 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.25 EJS43002.1 - 1e-73 248.0 0.0 1.2e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43002.1 - 5e-41 140.7 0.0 6.8e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43002.1 - 0.0002 20.8 0.0 0.00044 19.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EJS43002.1 - 0.0062 16.2 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EJS43002.1 - 0.018 14.0 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Nucleoporin_N PF08801.11 EJS43002.1 - 0.041 12.6 0.1 0.061 12.1 0.1 1.1 1 0 0 1 1 1 0 Nup133 N terminal like APH PF01636.23 EJS43002.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EJS43002.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EJS43002.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PigN PF04987.14 EJS43003.1 - 9.8e-132 440.0 48.0 1.3e-131 439.6 48.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EJS43003.1 - 2.6e-11 43.7 1.7 6.4e-09 35.9 0.2 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EJS43003.1 - 1.6e-09 37.6 0.1 2.6e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EJS43003.1 - 0.00013 21.4 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF1319 PF07028.11 EJS43003.1 - 0.12 12.6 0.3 0.25 11.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) DUF4083 PF13314.6 EJS43003.1 - 3 7.9 6.8 0.42 10.6 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) AAA PF00004.29 EJS43004.1 - 2.1e-50 170.5 0.0 5.2e-43 146.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EJS43004.1 - 3.9e-20 72.0 0.8 1.1e-19 70.7 0.1 2.2 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 EJS43004.1 - 2.5e-10 41.0 0.0 0.0018 18.7 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 EJS43004.1 - 3.4e-10 39.5 0.0 5.2e-07 29.4 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_14 PF13173.6 EJS43004.1 - 8.9e-07 29.0 0.0 0.0085 16.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EJS43004.1 - 1.2e-06 28.6 0.5 0.0057 16.6 0.0 3.3 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.6 EJS43004.1 - 2.3e-05 24.7 0.1 1.1 9.6 0.1 4.1 2 2 1 3 3 3 2 AAA domain RNA_helicase PF00910.22 EJS43004.1 - 0.0001 22.6 0.1 1.4 9.3 0.0 3.7 3 0 0 3 3 3 1 RNA helicase RuvB_N PF05496.12 EJS43004.1 - 0.00066 19.5 0.0 0.0058 16.4 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EJS43004.1 - 0.0011 19.2 0.0 0.016 15.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EJS43004.1 - 0.0011 19.0 0.0 0.62 10.1 0.0 3.3 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EJS43004.1 - 0.0016 18.0 0.0 0.72 9.4 0.1 3.9 2 2 1 4 4 4 1 AAA domain AAA_33 PF13671.6 EJS43004.1 - 0.0018 18.4 0.0 0.018 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EJS43004.1 - 0.0018 18.3 0.0 0.64 10.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EJS43004.1 - 0.0052 16.5 0.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 EJS43004.1 - 0.011 15.5 0.1 1.4 8.6 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 EJS43004.1 - 0.014 14.6 0.9 0.12 11.5 0.0 2.7 3 1 1 4 4 4 0 TIP49 P-loop domain Zeta_toxin PF06414.12 EJS43004.1 - 0.02 14.2 0.0 3.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Vps4_C PF09336.10 EJS43004.1 - 0.021 14.8 0.1 0.085 12.9 0.2 2.1 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 EJS43004.1 - 0.024 15.2 0.0 0.14 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EJS43004.1 - 0.031 13.5 0.1 0.13 11.5 0.0 2.0 3 0 0 3 3 3 0 KAP family P-loop domain ORF45 PF17620.2 EJS43004.1 - 0.04 14.0 0.5 0.55 10.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function Sigma54_activat PF00158.26 EJS43004.1 - 0.041 13.6 0.0 11 5.7 0.0 3.0 3 1 0 3 3 3 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EJS43004.1 - 0.045 13.6 4.8 1.4 8.8 0.0 3.7 4 1 0 4 4 3 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EJS43004.1 - 0.052 14.0 0.0 0.38 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EJS43004.1 - 0.072 12.8 0.0 6.4 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EJS43004.1 - 0.097 12.5 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DHO_dh PF01180.21 EJS43005.1 - 5.2e-98 327.9 0.0 5.8e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EJS43005.1 - 2.6e-05 23.4 0.1 0.00078 18.6 0.0 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Polysacc_deac_1 PF01522.21 EJS43005.1 - 0.01 15.7 0.0 0.16 11.9 0.0 2.2 1 1 1 2 2 2 0 Polysaccharide deacetylase Glu_synthase PF01645.17 EJS43005.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase IMPDH PF00478.25 EJS43005.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain FoP_duplication PF13865.6 EJS43006.1 - 2.5e-07 31.1 4.8 4.7e-07 30.3 4.8 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 EJS43006.1 - 3.3e-05 23.6 0.0 5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Syja_N PF02383.18 EJS43007.1 - 4.5e-82 275.9 2.7 6.2e-82 275.5 2.7 1.2 1 0 0 1 1 1 1 SacI homology domain IGPS PF00218.21 EJS43008.1 - 1.5e-96 322.5 0.0 1.9e-96 322.1 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 EJS43008.1 - 1.6e-51 174.8 0.0 2.7e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EJS43008.1 - 6.1e-09 35.9 0.5 1.9e-08 34.3 0.3 1.9 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.19 EJS43008.1 - 0.0001 22.1 0.1 0.00022 21.0 0.1 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain LDcluster4 PF18306.1 EJS43008.1 - 0.013 15.1 0.1 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 SLOG cluster4 family His_biosynth PF00977.21 EJS43008.1 - 0.049 13.1 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.14 EJS43008.1 - 0.17 11.0 0.0 0.36 10.0 0.0 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase PAC2 PF09754.9 EJS43009.1 - 3.5e-17 63.1 0.0 3.9e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 PAC2 family MOZART2 PF12926.7 EJS43009.1 - 0.094 12.3 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated FAT PF02259.23 EJS43011.1 - 1.1e-135 452.3 2.3 1.1e-135 452.3 2.3 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EJS43011.1 - 1.7e-74 250.8 0.3 2e-73 247.3 0.1 2.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EJS43011.1 - 1.4e-67 226.6 10.6 5.3e-62 208.5 0.1 5.4 4 2 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EJS43011.1 - 4.7e-42 142.4 5.3 1.4e-41 140.9 0.6 3.2 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 EJS43011.1 - 1.6e-18 66.2 0.3 4.4e-18 64.8 0.3 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 EJS43011.1 - 4e-12 46.4 5.4 0.011 16.1 0.0 8.9 8 1 2 10 10 10 2 HEAT repeats HEAT PF02985.22 EJS43011.1 - 5.2e-09 35.6 1.7 0.037 14.3 0.0 8.4 10 0 0 10 10 8 1 HEAT repeat HEAT_EZ PF13513.6 EJS43011.1 - 3e-08 34.0 3.0 0.52 10.9 0.0 9.5 10 1 1 11 11 10 1 HEAT-like repeat IFRD PF05004.13 EJS43011.1 - 0.00038 19.7 2.2 0.048 12.8 0.1 4.1 4 1 1 5 5 5 1 Interferon-related developmental regulator (IFRD) TPR_19 PF14559.6 EJS43011.1 - 0.0021 18.5 1.0 0.048 14.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat RTP1_C1 PF10363.9 EJS43011.1 - 0.0071 16.5 0.1 11 6.3 0.0 4.2 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 EJS43011.1 - 0.0086 16.6 1.5 0.51 11.0 0.0 4.3 4 0 0 4 4 3 1 Vacuolar 14 Fab1-binding region MOR2-PAG1_C PF14225.6 EJS43011.1 - 0.069 13.0 3.6 7.8 6.3 0.1 3.9 4 0 0 4 4 4 0 Cell morphogenesis C-terminal ATP13 PF12921.7 EJS43011.1 - 0.072 13.0 0.2 0.37 10.7 0.1 2.3 2 0 0 2 2 1 0 Mitochondrial ATPase expression TPR_12 PF13424.6 EJS43011.1 - 0.68 10.3 2.7 25 5.3 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 EJS43012.1 - 1.8e-31 109.4 24.1 1.8e-31 109.4 24.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.12 EJS43012.1 - 3.6 7.8 9.6 2 8.6 1.2 3.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Glyco_hydro_28 PF00295.17 EJS43013.1 - 2.3e-110 368.7 25.1 2.6e-110 368.5 25.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EJS43013.1 - 4.5e-06 26.6 24.5 4.5e-06 26.6 24.5 2.5 3 0 0 3 3 3 1 Right handed beta helix region PUF PF00806.19 EJS43014.1 - 4.1e-33 111.2 10.5 0.00031 20.2 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat FANCI_S1-cap PF14674.6 EJS43014.1 - 0.065 13.3 0.1 0.29 11.2 0.1 2.3 1 0 0 1 1 1 0 FANCI solenoid 1 cap Cpn60_TCP1 PF00118.24 EJS43015.1 - 5.6e-153 510.1 9.2 6.4e-153 509.9 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 EJS43015.1 - 0.023 15.0 0.1 0.18 12.2 0.0 2.5 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Cyclin_N PF00134.23 EJS43016.1 - 1.3e-07 31.4 2.1 2.8e-07 30.3 1.6 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain SYS1 PF09801.9 EJS43017.1 - 8.5e-51 171.9 12.9 1e-50 171.7 12.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX16 PF14138.6 EJS43018.1 - 4.7e-30 103.9 0.1 8.2e-30 103.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 VIT1 PF01988.19 EJS43018.1 - 0.18 11.6 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 VIT family Aa_trans PF01490.18 EJS43019.1 - 2.2e-89 300.0 22.8 2.6e-89 299.8 22.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mpp10 PF04006.12 EJS43020.1 - 1.7e-147 492.6 54.6 2.1e-147 492.2 54.6 1.0 1 0 0 1 1 1 1 Mpp10 protein Adaptin_N PF01602.20 EJS43021.1 - 1.4e-112 377.0 16.6 1.7e-112 376.7 16.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EJS43021.1 - 4.8e-13 49.5 1.1 4.8e-13 49.5 1.1 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 EJS43021.1 - 0.78 9.6 10.5 0.12 12.2 1.1 3.3 4 1 1 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RTP1_C1 PF10363.9 EJS43021.1 - 1.3 9.2 5.4 0.71 10.1 1.2 2.7 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DNA_pol_E_B PF04042.16 EJS43023.1 - 1.5e-51 174.8 0.1 2e-51 174.3 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EJS43023.1 - 8.8e-38 129.4 0.0 1.5e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain EIF_2_alpha PF07541.12 EJS43024.1 - 6.4e-39 132.6 0.1 1.4e-38 131.6 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EJS43024.1 - 2.4e-14 53.4 0.7 2.4e-14 53.4 0.7 1.9 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.9 EJS43024.1 - 0.049 14.2 1.4 0.19 12.4 0.2 2.2 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 LZ3wCH PF18517.1 EJS43024.1 - 0.33 11.1 2.5 0.71 10.0 0.0 2.8 4 1 1 5 5 5 0 Leucine zipper with capping helix domain Gp_dh_C PF02800.20 EJS43025.1 - 3.4e-72 241.2 0.0 5.9e-72 240.4 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EJS43025.1 - 1.9e-38 130.9 0.0 4e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EJS43025.1 - 0.01 15.9 1.9 0.016 15.3 0.4 2.3 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EJS43025.1 - 0.079 12.3 0.1 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-sulfurylase PF01747.17 EJS43026.1 - 2.3e-86 288.7 0.0 2.9e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EJS43026.1 - 1.7e-48 164.3 0.0 2.9e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain CTP_transf_like PF01467.26 EJS43026.1 - 0.045 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Cytidylyltransferase-like SPC12 PF06645.13 EJS43027.1 - 3.7e-24 84.6 0.2 4.4e-24 84.3 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Mannosyl_trans PF05007.13 EJS43028.1 - 4.4e-102 341.4 21.4 4.4e-102 341.4 21.4 1.9 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EJS43028.1 - 1.1e-13 51.0 9.9 1.1e-13 51.0 9.9 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EJS43028.1 - 1.7e-07 31.3 5.7 1.7e-07 31.3 5.7 2.1 1 1 1 2 2 2 1 Glycosyltransferase family 87 PMT_2 PF13231.6 EJS43028.1 - 1.3e-05 25.5 9.2 1.3e-05 25.5 9.2 2.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase ILVD_EDD PF00920.21 EJS43029.1 - 9.6e-210 697.6 0.1 1.1e-209 697.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Rotamase PF00639.21 EJS43030.1 - 1.5e-25 90.0 0.0 2e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EJS43030.1 - 1.4e-20 74.0 0.0 2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EJS43030.1 - 8.7e-08 32.1 2.7 1.4e-07 31.4 2.7 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 EJS43030.1 - 4.1e-06 27.6 0.0 5.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Acyl_CoA_thio PF02551.15 EJS43031.1 - 9.3e-60 200.2 5.1 6.2e-45 152.3 2.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.6 EJS43031.1 - 2.6e-32 113.1 0.0 7.4e-32 111.6 0.0 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily 3-HAO PF06052.12 EJS43032.1 - 3e-73 244.4 0.1 3.6e-73 244.2 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EJS43032.1 - 2.1e-05 24.1 0.0 3.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EJS43032.1 - 0.0026 17.4 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 Cupin zinc_ribbon_10 PF10058.9 EJS43032.1 - 0.029 14.1 1.6 0.33 10.7 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein AraC_binding PF02311.19 EJS43032.1 - 0.099 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Pro_isomerase PF00160.21 EJS43033.1 - 2e-42 145.2 0.0 3.3e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EJS43033.1 - 2.1e-10 39.9 6.5 6.8e-06 25.8 1.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJS43033.1 - 8.7e-08 31.7 7.7 9.4e-07 28.4 1.7 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EJS43033.1 - 1.2e-05 25.1 5.5 0.035 14.3 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EJS43033.1 - 1.8e-05 25.0 0.1 0.00047 20.4 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJS43033.1 - 0.0099 16.5 0.0 0.13 13.0 0.0 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EJS43033.1 - 0.25 11.0 1.1 3.6 7.4 0.1 3.0 2 1 1 3 3 3 0 TPR repeat DUF357 PF04010.13 EJS43033.1 - 0.41 10.8 1.7 2.5 8.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Pet191_N PF10203.9 EJS43034.1 - 5.7e-23 81.0 3.3 8.9e-23 80.4 3.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 EJS43034.1 - 0.021 14.8 1.1 7 6.8 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 EJS43034.1 - 0.26 11.5 4.7 0.61 10.3 0.3 2.8 3 0 0 3 3 3 0 CHCH domain CX9C PF16860.5 EJS43034.1 - 1 9.5 7.0 2.4 8.3 0.5 3.1 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, HECT PF00632.25 EJS43035.1 - 1.1e-78 264.8 3.7 2.3e-78 263.8 3.7 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Voltage_CLC PF00654.20 EJS43036.1 - 1.4e-77 261.4 23.5 1.4e-77 261.4 23.5 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EJS43036.1 - 1.5e-16 60.6 0.0 2.4e-07 31.1 0.0 3.4 3 0 0 3 3 3 2 CBS domain Urb2 PF10441.9 EJS43037.1 - 3.7e-53 180.5 2.1 3.7e-53 180.5 2.1 2.8 4 0 0 4 4 4 1 Urb2/Npa2 family MucB_RseB PF03888.14 EJS43037.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 MucB/RseB N-terminal domain Nucleopor_Nup85 PF07575.13 EJS43038.1 - 7.3e-185 615.8 1.1 8.4e-185 615.6 1.1 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin CDC27 PF09507.10 EJS43039.1 - 0.055 12.9 36.1 0.031 13.7 32.8 2.1 2 1 0 2 2 2 0 DNA polymerase subunit Cdc27 SseC PF04888.12 EJS43039.1 - 0.75 9.3 6.2 1.1 8.8 6.2 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Vps55 PF04133.14 EJS43040.1 - 5.2e-42 142.5 8.0 5.9e-42 142.3 8.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 eIF-5a PF01287.20 EJS43041.1 - 4.2e-30 103.7 0.5 6e-30 103.2 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EJS43041.1 - 0.0037 17.3 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Cytochrom_C PF00034.21 EJS43042.1 - 7.1e-12 46.3 0.2 1.3e-11 45.4 0.2 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EJS43042.1 - 2.8e-07 30.8 1.5 2.3e-06 27.8 1.5 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EJS43042.1 - 0.044 13.5 0.4 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 Cytochrome c-550 domain NAD_kinase PF01513.21 EJS43043.1 - 2.4e-94 315.8 0.0 3.8e-94 315.1 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EJS43043.1 - 0.0019 17.8 0.0 0.018 14.6 0.0 2.5 3 0 0 3 3 3 1 Diacylglycerol kinase catalytic domain zf-CpG_bind_C PF12269.8 EJS43043.1 - 3.1 7.5 7.7 1.8 8.3 2.8 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Isy1 PF06246.12 EJS43044.1 - 4.8e-53 180.3 17.6 6.9e-52 176.5 17.6 1.9 1 1 0 1 1 1 1 Isy1-like splicing family HD_6 PF18019.1 EJS43044.1 - 0.076 13.1 0.2 0.076 13.1 0.2 1.9 2 0 0 2 2 2 0 HD domain FAD_binding_2 PF00890.24 EJS43045.1 - 7.8e-71 239.3 0.0 8.9e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJS43045.1 - 5.9e-08 32.7 0.0 9.4e-06 25.4 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJS43045.1 - 2.1e-06 27.8 0.1 7.5e-06 26.1 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EJS43045.1 - 0.00014 21.2 0.4 0.0085 15.3 0.1 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EJS43045.1 - 0.00024 19.9 0.3 0.39 9.3 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 EJS43045.1 - 0.00037 19.8 0.6 0.0033 16.7 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EJS43045.1 - 0.0071 15.4 0.0 0.063 12.3 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EJS43045.1 - 0.064 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EJS43045.1 - 0.17 11.9 0.1 3 7.8 0.1 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 EJS43045.1 - 0.18 11.1 0.9 12 5.2 0.0 2.9 3 0 0 3 3 3 0 GMC oxidoreductase LRR_6 PF13516.6 EJS43046.1 - 0.0071 16.3 2.7 3 8.1 0.0 5.7 7 0 0 7 7 7 1 Leucine Rich repeat DUF3683 PF12447.8 EJS43046.1 - 1.4 9.1 3.9 98 3.1 1.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3683) FSAP_sig_propep PF03032.15 EJS43047.1 - 5.4 7.1 16.5 15 5.7 16.5 1.8 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide KCH PF16944.5 EJS43048.1 - 7.5e-94 314.2 18.2 9.7e-94 313.8 18.2 1.1 1 0 0 1 1 1 1 Fungal potassium channel Hit1_C PF18268.1 EJS43049.1 - 5.8e-41 138.5 1.8 5.8e-41 138.5 1.8 1.6 2 0 0 2 2 2 1 Hit1 C-terminal zf-HIT PF04438.16 EJS43049.1 - 1.8e-12 46.9 11.4 4e-12 45.8 11.4 1.6 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 EJS43049.1 - 0.0017 18.1 0.0 0.0041 16.9 0.0 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-Mss51 PF13824.6 EJS43049.1 - 0.2 11.7 4.7 0.56 10.4 4.7 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EJS43049.1 - 1.5 8.9 13.9 0.25 11.5 10.0 1.7 2 0 0 2 2 2 0 MYND finger Clat_adaptor_s PF01217.20 EJS43050.1 - 3.6e-57 192.3 1.5 4.1e-57 192.1 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Endothelin PF00322.17 EJS43050.1 - 0.21 11.2 2.0 0.64 9.7 0.7 2.1 2 0 0 2 2 2 0 Endothelin family Pkinase PF00069.25 EJS43051.1 - 2.5e-35 122.1 0.0 4.2e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43051.1 - 1.6e-14 53.8 0.0 2.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJS43051.1 - 0.003 16.9 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EJS43051.1 - 0.17 11.1 0.0 0.6 9.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like LicD PF04991.13 EJS43052.1 - 2.7e-51 174.9 3.8 2.7e-51 174.9 3.8 3.0 3 1 1 4 4 4 1 LicD family Lipase_chap PF03280.14 EJS43052.1 - 0.025 14.5 0.3 0.38 10.7 0.0 2.4 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein Retrotrans_gag PF03732.17 EJS43052.1 - 0.073 13.4 0.5 7.3 6.9 0.1 3.1 2 0 0 2 2 2 0 Retrotransposon gag protein TFIIS_C PF01096.18 EJS43053.1 - 3e-17 62.2 1.6 3e-17 62.2 1.6 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EJS43053.1 - 3.4e-17 62.0 9.6 2.6e-14 52.8 0.5 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 EJS43053.1 - 6.9e-06 26.0 5.7 0.025 14.6 0.1 2.9 2 1 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 EJS43053.1 - 0.0013 18.2 6.1 0.081 12.5 2.4 2.9 2 1 0 2 2 2 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 EJS43053.1 - 0.0022 17.4 12.8 0.78 9.2 0.5 4.2 4 0 0 4 4 4 2 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 EJS43053.1 - 0.0051 16.8 3.3 0.016 15.1 0.3 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain IBR PF01485.21 EJS43053.1 - 0.0053 17.0 5.3 1.1 9.5 1.8 2.5 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain zinc_ribbon_4 PF13717.6 EJS43053.1 - 0.0076 16.1 7.0 5.4 7.0 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon domain C1_1 PF00130.22 EJS43053.1 - 0.0093 15.8 1.9 1.5 8.8 0.1 2.5 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TackOD1 PF18551.1 EJS43053.1 - 0.011 15.4 5.2 1 9.0 0.7 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-H2C2_2 PF13465.6 EJS43053.1 - 0.014 15.8 3.0 0.35 11.4 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zinc_ribbon_2 PF13240.6 EJS43053.1 - 0.016 14.9 11.7 0.41 10.4 0.3 4.0 3 2 0 3 3 3 0 zinc-ribbon domain zf-RING_7 PF02591.15 EJS43053.1 - 0.032 14.4 6.2 2.9 8.1 0.1 4.2 5 0 0 5 5 4 0 C4-type zinc ribbon domain HypA PF01155.19 EJS43053.1 - 0.055 13.5 6.9 7.3 6.6 0.3 3.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA tRNA-synt_1f PF01921.18 EJS43053.1 - 0.074 12.0 0.1 0.086 11.7 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF2072 PF09845.9 EJS43053.1 - 0.1 12.9 5.6 0.16 12.2 0.1 2.8 1 1 2 3 3 3 0 Zn-ribbon containing protein GATA PF00320.27 EJS43053.1 - 0.13 11.9 0.5 0.13 11.9 0.5 2.9 3 1 0 3 3 3 0 GATA zinc finger Nop10p PF04135.12 EJS43053.1 - 0.13 12.3 1.0 0.36 10.9 0.1 2.2 1 1 1 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family DUF3797 PF12677.7 EJS43053.1 - 0.16 11.9 3.5 0.62 10.0 1.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) DUF3268 PF11672.8 EJS43053.1 - 0.18 12.1 2.0 0.38 11.1 1.1 1.9 2 0 0 2 2 2 0 zinc-finger-containing domain CpXC PF14353.6 EJS43053.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.9 1 1 2 3 3 3 0 CpXC protein zinc-ribbons_6 PF07191.12 EJS43053.1 - 0.19 11.8 7.0 4.3 7.4 0.2 2.7 2 1 0 2 2 2 0 zinc-ribbons Terminase_GpA PF05876.12 EJS43053.1 - 0.25 9.8 1.5 0.37 9.3 0.6 1.6 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) Rubredoxin PF00301.20 EJS43053.1 - 0.28 11.2 4.9 32 4.6 0.3 3.3 3 0 0 3 3 3 0 Rubredoxin Nudix_N_2 PF14803.6 EJS43053.1 - 0.33 10.9 9.7 1.8 8.6 2.0 3.8 3 1 0 3 3 3 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 EJS43053.1 - 0.34 11.1 11.6 5.4 7.2 0.1 3.5 3 1 0 3 3 3 0 Zinc ribbon domain zf-RING_5 PF14634.6 EJS43053.1 - 0.47 10.5 6.1 3.2 7.8 0.6 2.9 3 0 0 3 3 3 0 zinc-RING finger domain zf-RRN7 PF11781.8 EJS43053.1 - 0.48 10.2 0.1 0.48 10.2 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-CSL PF05207.13 EJS43053.1 - 0.77 9.5 5.2 0.69 9.7 0.2 2.3 2 0 0 2 2 2 0 CSL zinc finger DpnI PF06044.12 EJS43053.1 - 0.81 9.3 3.6 6.2 6.4 0.4 2.1 1 1 0 2 2 2 0 Dam-replacing family Stc1 PF12898.7 EJS43053.1 - 0.85 10.2 7.5 1.5 9.4 0.6 2.3 1 1 1 2 2 2 0 Stc1 domain Ogr_Delta PF04606.12 EJS43053.1 - 0.87 9.6 9.8 0.35 10.9 5.3 2.4 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger zf-NADH-PPase PF09297.11 EJS43053.1 - 1.1 9.0 0.1 1.1 9.0 0.1 3.2 4 0 0 4 4 3 0 NADH pyrophosphatase zinc ribbon domain Baculo_LEF5_C PF11792.8 EJS43053.1 - 1.4 8.6 6.7 0.15 11.7 0.8 2.4 2 1 0 2 2 1 0 Baculoviridae late expression factor 5 C-terminal domain OrfB_Zn_ribbon PF07282.11 EJS43053.1 - 1.6 8.7 7.2 21 5.1 2.6 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-TFIIB PF13453.6 EJS43053.1 - 2 7.8 6.5 0.34 10.3 0.7 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger PADR1 PF08063.12 EJS43053.1 - 2.5 8.0 9.8 22 4.9 0.0 3.4 3 1 0 3 3 3 0 PADR1 (NUC008) domain zf-AN1 PF01428.16 EJS43053.1 - 3.8 7.7 9.0 17 5.7 0.2 3.4 3 1 0 3 3 3 0 AN1-like Zinc finger zinc_ribbon_15 PF17032.5 EJS43053.1 - 5.2 7.9 11.7 27 5.6 7.5 3.1 1 1 0 2 2 2 0 zinc-ribbon family Zn_Tnp_IS91 PF14319.6 EJS43053.1 - 5.3 7.2 7.5 6.3 6.9 2.0 2.8 1 1 0 2 2 2 0 Transposase zinc-binding domain zf-C2H2_4 PF13894.6 EJS43053.1 - 5.8 8.0 11.6 31 5.8 1.1 3.8 4 0 0 4 4 3 0 C2H2-type zinc finger Cpn60_TCP1 PF00118.24 EJS43054.1 - 1.1e-151 505.8 2.3 1.3e-151 505.6 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.21 EJS43054.1 - 0.11 12.5 0.4 4.8 7.3 0.1 2.4 2 0 0 2 2 2 0 Resolvase, N terminal domain Actin PF00022.19 EJS43055.1 - 7.4e-90 301.5 0.0 1.8e-87 293.6 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EJS43055.1 - 4.5e-05 22.4 0.0 0.013 14.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EJS43055.1 - 0.0023 18.3 0.0 0.009 16.4 0.0 2.0 2 1 0 2 2 2 1 Cell division protein FtsA FAT PF02259.23 EJS43056.1 - 2.1e-130 435.0 0.2 2.1e-130 435.0 0.2 2.1 2 1 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EJS43056.1 - 2.4e-73 247.0 0.0 5.8e-73 245.8 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EJS43056.1 - 1.5e-64 216.8 20.2 1.1e-60 204.2 2.0 5.8 5 2 0 5 5 5 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EJS43056.1 - 5.2e-41 139.1 0.7 5.2e-41 139.1 0.7 2.8 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 EJS43056.1 - 4.1e-17 61.7 0.2 1.5e-16 59.9 0.2 2.1 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 EJS43056.1 - 6.2e-15 55.4 2.4 0.025 15.0 0.0 8.5 7 2 0 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 EJS43056.1 - 4.1e-13 49.5 0.9 0.02 15.4 0.0 10.0 8 1 2 10 10 10 3 HEAT-like repeat HEAT PF02985.22 EJS43056.1 - 1.3e-08 34.3 10.4 0.0067 16.6 0.0 8.5 10 0 0 10 10 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EJS43056.1 - 0.00013 22.5 5.9 0.24 12.0 0.0 5.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EJS43056.1 - 0.0017 18.0 14.0 3.7 7.0 0.0 6.1 5 1 1 6 6 6 2 CLASP N terminal HrpB1_HrpK PF09613.10 EJS43056.1 - 0.0025 17.5 0.0 0.37 10.4 0.0 3.2 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) DUF3437 PF11919.8 EJS43056.1 - 0.0059 16.5 0.1 0.33 10.9 0.0 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) TPR_19 PF14559.6 EJS43056.1 - 0.015 15.8 0.3 2.8 8.5 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat Telomere_reg-2 PF10193.9 EJS43056.1 - 9.3 6.8 9.4 27 5.2 0.0 5.8 6 0 0 6 6 6 0 Telomere length regulation protein Rep_fac_C PF08542.11 EJS43057.1 - 5.7e-19 68.3 0.0 1.2e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EJS43057.1 - 5.3e-16 59.2 0.0 1.2e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EJS43057.1 - 6.8e-13 48.7 0.0 2.8e-11 43.5 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EJS43057.1 - 3.7e-07 30.3 0.0 6.4e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EJS43057.1 - 2.4e-05 24.6 0.0 0.00028 21.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EJS43057.1 - 2.6e-05 24.0 0.0 6.6e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EJS43057.1 - 4e-05 23.5 0.0 7.4e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJS43057.1 - 0.0001 22.7 0.0 0.0066 16.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EJS43057.1 - 0.0002 21.4 0.0 0.0024 17.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EJS43057.1 - 0.00023 21.5 0.0 0.00062 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 EJS43057.1 - 0.00037 20.0 0.0 0.0091 15.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 EJS43057.1 - 0.0012 18.9 0.2 0.0098 15.9 0.0 2.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DUF815 PF05673.13 EJS43057.1 - 0.0023 17.1 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EJS43057.1 - 0.0033 16.9 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 EJS43057.1 - 0.0044 17.4 0.0 0.02 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJS43057.1 - 0.0051 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EJS43057.1 - 0.012 15.4 0.0 0.032 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EJS43057.1 - 0.014 15.9 0.0 0.024 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.8 EJS43057.1 - 0.024 14.6 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III AAA_5 PF07728.14 EJS43057.1 - 0.042 13.8 0.1 0.37 10.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EJS43057.1 - 0.047 12.9 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_3 PF07726.11 EJS43057.1 - 0.077 12.9 0.0 0.57 10.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EJS43057.1 - 0.08 12.2 0.0 0.21 10.8 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) YAF2_RYBP PF17219.3 EJS43057.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif AAA_18 PF13238.6 EJS43057.1 - 0.095 13.2 0.1 0.34 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EJS43057.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ham1p_like PF01725.16 EJS43058.1 - 7e-52 176.1 0.1 7.8e-52 175.9 0.1 1.0 1 0 0 1 1 1 1 Ham1 family ATP_bind_1 PF03029.17 EJS43059.1 - 1.9e-82 276.7 0.1 3.2e-82 275.9 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EJS43059.1 - 2e-07 30.7 0.1 5.7e-06 26.0 0.1 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EJS43059.1 - 6.5e-05 22.7 0.0 0.00023 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EJS43059.1 - 6.8e-05 23.0 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EJS43059.1 - 0.0004 20.5 0.0 0.0063 16.6 0.0 2.5 2 1 0 2 2 1 1 50S ribosome-binding GTPase NACHT PF05729.12 EJS43059.1 - 0.00044 20.2 0.0 0.0016 18.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 EJS43059.1 - 0.00056 19.7 0.0 0.062 13.0 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EJS43059.1 - 0.00075 19.4 0.1 1.5 8.7 0.0 3.3 2 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EJS43059.1 - 0.001 19.3 0.0 0.0039 17.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain MeaB PF03308.16 EJS43059.1 - 0.0027 16.7 0.0 0.4 9.6 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EJS43059.1 - 0.0031 17.1 0.0 0.071 12.6 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B SRP54 PF00448.22 EJS43059.1 - 0.0076 15.9 0.0 0.039 13.6 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain KTI12 PF08433.10 EJS43059.1 - 0.0094 15.4 0.3 0.19 11.1 0.0 2.2 2 0 0 2 2 2 1 Chromatin associated protein KTI12 PRK PF00485.18 EJS43059.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Arf PF00025.21 EJS43059.1 - 0.012 15.1 0.0 0.76 9.2 0.0 3.0 3 1 1 4 4 4 0 ADP-ribosylation factor family SRPRB PF09439.10 EJS43059.1 - 0.012 15.0 0.2 0.94 8.9 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 EJS43059.1 - 0.013 15.7 0.0 0.91 9.8 0.0 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EJS43059.1 - 0.014 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 EJS43059.1 - 0.016 14.8 0.2 0.2 11.3 0.2 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EJS43059.1 - 0.016 15.8 0.6 0.044 14.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EJS43059.1 - 0.02 15.3 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EJS43059.1 - 0.02 14.1 0.1 0.076 12.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 EJS43059.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EJS43059.1 - 0.023 14.5 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Microtub_bd PF16796.5 EJS43059.1 - 0.038 13.9 0.0 4.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Microtubule binding G-alpha PF00503.20 EJS43059.1 - 1.1 8.4 6.0 2.7 7.1 0.0 3.2 3 1 1 4 4 4 0 G-protein alpha subunit Gly_transf_sug PF04488.15 EJS43060.1 - 2.3e-17 63.4 0.1 1.2e-16 61.1 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif AI-2E_transport PF01594.16 EJS43060.1 - 0.013 14.7 0.7 0.021 14.0 0.7 1.3 1 0 0 1 1 1 0 AI-2E family transporter DUF3450 PF11932.8 EJS43060.1 - 0.023 14.0 4.6 0.034 13.4 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TrbL PF04610.14 EJS43060.1 - 0.16 11.7 0.7 0.24 11.1 0.0 1.5 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Septin PF00735.18 EJS43061.1 - 1.8e-110 368.7 0.1 2.9e-110 368.0 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EJS43061.1 - 1.3e-08 34.9 0.0 3.2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EJS43061.1 - 5.5e-05 23.7 0.9 0.00016 22.2 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 EJS43061.1 - 6.9e-05 22.3 0.1 6.9e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 EJS43061.1 - 7.1e-05 22.9 7.9 0.001 19.1 0.4 3.0 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EJS43061.1 - 0.00024 21.0 1.8 0.00024 21.0 1.8 3.6 3 1 0 3 3 3 1 RsgA GTPase IIGP PF05049.13 EJS43061.1 - 0.003 16.7 0.1 0.0056 15.8 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 EJS43061.1 - 0.0063 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EJS43061.1 - 0.025 14.3 0.1 0.072 12.8 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EJS43061.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EJS43061.1 - 0.073 12.7 0.2 0.2 11.2 0.2 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 EJS43061.1 - 0.1 12.1 2.3 0.46 10.0 0.5 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 EJS43061.1 - 0.13 11.4 0.1 0.13 11.4 0.1 2.6 2 1 0 3 3 3 0 G-protein alpha subunit PduV-EutP PF10662.9 EJS43061.1 - 0.13 12.0 0.7 3.6 7.3 0.2 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 EJS43061.1 - 0.54 10.7 15.4 4 7.9 7.1 2.7 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.27 EJS43062.1 - 1.9e-44 149.5 8.0 7.7e-18 64.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AIM24 PF01987.17 EJS43063.1 - 5e-32 111.3 0.0 6.6e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 NuA4 PF09340.10 EJS43064.1 - 7e-22 77.1 6.0 1.2e-21 76.4 6.0 1.4 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Tmemb_cc2 PF10267.9 EJS43065.1 - 2.5e-06 26.9 11.5 4.2e-06 26.2 11.5 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Tropomyosin_1 PF12718.7 EJS43065.1 - 4.7e-05 23.6 5.4 4.7e-05 23.6 5.4 2.0 2 0 0 2 2 2 1 Tropomyosin like Lge1 PF11488.8 EJS43065.1 - 0.0079 16.3 3.7 0.026 14.7 3.7 1.9 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 CALCOCO1 PF07888.11 EJS43065.1 - 0.024 13.5 6.4 0.042 12.7 6.4 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IZUMO PF15005.6 EJS43065.1 - 0.037 14.5 1.4 0.037 14.5 1.4 1.9 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated SesA PF17107.5 EJS43065.1 - 0.19 11.9 2.8 0.17 12.1 1.4 1.6 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Occludin_ELL PF07303.13 EJS43065.1 - 0.68 10.7 9.7 0.11 13.2 3.5 2.5 2 0 0 2 2 2 0 Occludin homology domain DUF2203 PF09969.9 EJS43065.1 - 1.8 9.3 4.2 1 10.1 1.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Stevor PF17410.2 EJS43065.1 - 2.5 7.6 9.2 0.13 11.8 3.5 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Inhibitor_I10 PF12559.8 EJS43065.1 - 3.2 8.1 8.1 2.1 8.7 0.2 2.8 3 0 0 3 3 3 0 Serine endopeptidase inhibitors PCI PF01399.27 EJS43066.1 - 2.7e-12 47.1 0.0 7.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain Tmemb_14 PF03647.13 EJS43067.1 - 4.1e-21 75.5 7.8 4.5e-21 75.4 7.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 EJS43067.1 - 0.027 14.7 1.4 0.062 13.6 1.4 1.6 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 BIV_Env PF05858.12 EJS43067.1 - 0.14 10.3 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) G-gamma PF00631.22 EJS43068.1 - 1.9e-27 95.1 0.3 3.8e-27 94.1 0.3 1.5 1 1 0 1 1 1 1 GGL domain FYVE_2 PF02318.16 EJS43068.1 - 0.063 13.5 0.3 0.063 13.5 0.3 1.5 2 0 0 2 2 2 0 FYVE-type zinc finger TPR_2 PF07719.17 EJS43069.1 - 7.1e-07 28.9 1.8 0.00055 19.9 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EJS43069.1 - 0.001 19.6 2.2 1.1 10.0 0.0 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJS43069.1 - 0.0014 19.3 0.0 5.6 8.1 0.0 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJS43069.1 - 0.0028 17.4 0.4 0.14 12.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Cucumopine_C PF18631.1 EJS43069.1 - 0.0033 17.4 0.1 0.27 11.2 0.1 2.4 2 0 0 2 2 2 1 Cucumopine synthase C-terminal helical bundle domain TPR_9 PF13371.6 EJS43069.1 - 0.0045 17.1 0.0 0.034 14.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJS43069.1 - 0.0061 16.8 0.2 1.8 8.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EJS43069.1 - 0.0078 16.3 2.7 0.88 9.9 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EJS43069.1 - 0.025 14.3 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 EJS43069.1 - 0.026 14.6 0.1 6.7 7.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EJS43069.1 - 0.063 13.9 0.0 0.53 11.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EJS43069.1 - 0.097 13.2 0.0 2.6 8.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.7 EJS43070.1 - 4.1e-06 27.0 18.3 2.6 8.6 0.2 8.5 4 1 3 8 8 8 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EJS43070.1 - 1e-05 25.3 0.3 2.5e-05 24.1 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJS43070.1 - 0.0011 18.8 0.1 0.0038 17.1 0.1 2.1 1 0 0 1 1 1 1 F-box domain PUF PF00806.19 EJS43071.1 - 6.9e-33 110.5 0.2 2.3e-06 27.0 0.1 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EJS43071.1 - 1.4e-07 31.2 0.0 3.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 EJS43073.1 - 4.3e-74 244.5 0.6 1.1e-23 83.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.21 EJS43074.1 - 2.7e-40 138.4 0.0 6.2e-38 130.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Peptidase_C12 PF01088.21 EJS43075.1 - 1.8e-43 148.8 0.0 2e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Sod_Fe_C PF02777.18 EJS43076.1 - 1.2e-15 57.5 1.6 7.8e-13 48.5 1.6 2.7 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Pik1 PF11522.8 EJS43076.1 - 0.0048 16.8 0.7 0.012 15.5 0.3 1.9 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 ESCRT-II PF05871.12 EJS43077.1 - 2e-46 157.7 0.9 2.5e-46 157.4 0.9 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Sod_Cu PF00080.20 EJS43078.1 - 1e-47 161.9 1.1 1.2e-47 161.7 1.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PfkB PF00294.24 EJS43079.1 - 3e-80 269.8 1.2 3.3e-80 269.6 1.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EJS43079.1 - 1.8e-06 27.5 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Na_Ca_ex PF01699.24 EJS43080.1 - 3e-59 199.3 32.2 9.1e-33 113.3 12.1 3.4 3 1 0 3 3 3 2 Sodium/calcium exchanger protein CPSase_L_D2 PF02786.17 EJS43081.1 - 2.7e-108 360.3 0.0 1.7e-82 276.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EJS43081.1 - 1.4e-38 132.0 0.2 3.1e-38 130.9 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EJS43081.1 - 1.2e-16 60.8 0.0 4.7e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EJS43081.1 - 2.6e-15 56.5 0.3 9.1e-07 28.6 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EJS43081.1 - 6.9e-15 55.0 0.0 9.4e-08 31.9 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 EJS43081.1 - 0.00024 21.2 0.0 0.00098 19.3 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain ATP-grasp_5 PF13549.6 EJS43081.1 - 0.0012 18.3 0.0 0.066 12.7 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EJS43081.1 - 0.0019 18.0 0.1 0.78 9.5 0.0 2.8 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.6 EJS43081.1 - 0.0019 17.8 0.1 0.061 12.9 0.1 2.8 2 1 0 2 2 2 1 ATP-grasp domain eIF2A PF08662.11 EJS43081.1 - 0.088 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A LAMTOR5 PF16672.5 EJS43081.1 - 0.11 12.4 1.5 12 5.9 0.0 2.8 3 0 0 3 3 2 0 Ragulator complex protein LAMTOR5 GDP_Man_Dehyd PF16363.5 EJS43081.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase UBA_6 PF18039.1 EJS43081.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Myotub-related PF06602.14 EJS43082.1 - 1.7e-133 444.9 1.4 2.2e-133 444.5 1.4 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 EJS43082.1 - 0.0014 18.5 0.0 0.0052 16.6 0.0 2.0 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 EJS43082.1 - 0.0085 15.7 0.5 0.016 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 EJS43082.1 - 0.015 15.1 0.1 0.096 12.5 0.0 2.3 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EJS43082.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family HTH_29 PF13551.6 EJS43082.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix CMD PF02627.20 EJS43083.1 - 3.1e-07 30.4 0.0 2.3e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Nnf1 PF03980.14 EJS43084.1 - 3.9e-29 101.2 9.2 7.2e-29 100.4 9.2 1.5 1 0 0 1 1 1 1 Nnf1 DUF4795 PF16043.5 EJS43084.1 - 0.0048 16.5 8.2 0.063 12.9 2.5 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF4795) Ta0938 PF11494.8 EJS43084.1 - 0.021 15.1 0.1 0.051 13.9 0.1 1.6 1 1 0 1 1 1 0 Ta0938 OmpH PF03938.14 EJS43084.1 - 0.041 14.2 1.6 0.041 14.2 1.6 2.3 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF948 PF06103.11 EJS43084.1 - 0.074 13.3 0.6 1.6 9.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Jnk-SapK_ap_N PF09744.9 EJS43084.1 - 0.079 13.2 10.2 0.14 12.4 10.2 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc29 PF17082.5 EJS43084.1 - 0.13 12.1 4.0 0.34 10.7 3.9 1.8 1 1 0 1 1 1 0 Spindle Pole Component 29 Cdh1_DBD_1 PF18196.1 EJS43084.1 - 0.17 12.2 6.0 0.42 10.9 0.3 2.2 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 V-SNARE PF05008.15 EJS43084.1 - 0.24 11.8 8.8 0.34 11.3 1.8 2.8 3 0 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus DUF4407 PF14362.6 EJS43084.1 - 0.31 10.3 5.4 0.65 9.3 4.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 EJS43084.1 - 0.64 10.2 7.6 0.45 10.7 4.7 2.1 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 EJS43084.1 - 1.1 9.8 10.5 0.83 10.2 6.9 2.3 1 1 1 2 2 2 0 Spectrin repeat Fungal_TACC PF12709.7 EJS43084.1 - 1.2 9.6 7.6 0.12 12.9 1.5 2.4 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1664 PF07889.12 EJS43084.1 - 1.5 8.8 7.0 2 8.5 0.9 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PNPase PF03726.14 EJS43084.1 - 3.6 8.2 10.6 2.2 8.9 3.4 2.4 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain PHM7_cyt PF14703.6 EJS43084.1 - 3.9 7.7 8.3 27 4.9 6.7 2.6 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Troponin PF00992.20 EJS43084.1 - 4.9 7.4 14.8 88 3.4 0.8 2.2 1 1 1 2 2 2 0 Troponin DUF16 PF01519.16 EJS43084.1 - 5.8 7.5 9.8 1.1e+02 3.3 9.6 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 Ribosomal_S7 PF00177.21 EJS43085.1 - 1.3e-33 115.8 0.4 1.7e-33 115.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e TRAM_LAG1_CLN8 PF03798.16 EJS43086.1 - 1.4e-32 113.0 20.8 1.4e-32 113.0 20.8 1.4 2 0 0 2 2 2 1 TLC domain Peptidase_M48_N PF16491.5 EJS43087.1 - 2.4e-60 203.5 10.3 2.4e-60 203.5 10.3 2.2 2 0 0 2 2 2 2 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EJS43087.1 - 2.2e-45 154.9 0.0 4e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EJS43087.1 - 0.0027 17.0 0.2 0.0057 15.9 0.2 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2268 PF10026.9 EJS43087.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.9 EJS43087.1 - 0.024 14.5 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 SprT-like family DUF4157 PF13699.6 EJS43087.1 - 0.047 13.9 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) JmjC PF02373.22 EJS43088.1 - 4.4e-40 136.6 0.4 1e-39 135.5 0.4 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EJS43088.1 - 2.8e-12 46.3 4.5 2.8e-12 46.3 4.5 2.4 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.17 EJS43088.1 - 3.9e-11 42.7 0.3 1e-10 41.4 0.3 1.8 1 0 0 1 1 1 1 jmjN domain Zf_RING PF16744.5 EJS43088.1 - 0.073 13.2 1.8 0.29 11.3 1.8 2.0 1 0 0 1 1 1 0 KIAA1045 RING finger zf-HC5HC2H PF13771.6 EJS43088.1 - 0.23 11.8 2.8 0.24 11.7 0.0 2.4 3 0 0 3 3 3 0 PHD-like zinc-binding domain Prim_Zn_Ribbon PF08273.12 EJS43088.1 - 2.7 8.3 6.1 2.8 8.3 0.1 2.9 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase PHD_2 PF13831.6 EJS43088.1 - 2.8 7.6 6.9 0.52 9.9 0.6 2.6 2 0 0 2 2 2 0 PHD-finger zf-rbx1 PF12678.7 EJS43088.1 - 2.9 8.2 6.5 0.59 10.5 2.3 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain Spt5_N PF11942.8 EJS43088.1 - 3.4 8.7 6.4 55 4.8 0.0 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ATP-synt_ab PF00006.25 EJS43089.1 - 3e-62 210.1 0.0 4.8e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EJS43089.1 - 5.4e-24 84.5 0.8 1.5e-23 83.0 0.8 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 EJS43089.1 - 0.0017 17.7 0.2 0.0028 17.0 0.2 1.4 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.22 EJS43089.1 - 0.011 15.0 0.8 0.078 12.2 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain T3SS_ATPase_C PF18269.1 EJS43089.1 - 0.02 14.7 0.5 0.12 12.2 0.5 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RsgA_GTPase PF03193.16 EJS43089.1 - 0.038 13.9 0.1 0.088 12.7 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EJS43089.1 - 0.043 13.7 0.2 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EJS43089.1 - 0.044 14.2 0.1 0.63 10.5 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJS43089.1 - 0.075 13.4 0.1 0.28 11.6 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EJS43089.1 - 0.088 13.1 1.0 0.49 10.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EJS43089.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase CSD2 PF17876.1 EJS43089.1 - 0.17 12.1 0.2 3.3 7.9 0.1 2.7 2 0 0 2 2 2 0 Cold shock domain Ribosomal_S7 PF00177.21 EJS43090.1 - 2.1e-37 128.1 2.3 3e-37 127.5 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MFS_1 PF07690.16 EJS43091.1 - 1.5e-22 80.0 24.2 1.4e-16 60.4 20.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EJS43091.1 - 0.00041 19.3 10.9 0.00041 19.3 10.9 2.5 2 1 1 3 3 3 2 MFS_1 like family OATP PF03137.20 EJS43091.1 - 0.0005 18.5 15.0 0.0043 15.4 2.1 3.2 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EJS43091.1 - 0.02 13.8 22.7 0.03 13.2 9.9 3.2 3 1 0 3 3 3 0 Sugar (and other) transporter ENTH PF01417.20 EJS43092.1 - 6.5e-44 149.0 0.1 1.1e-43 148.3 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EJS43092.1 - 0.00043 19.4 0.0 0.00062 18.8 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 EJS43092.1 - 0.0015 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 VHS domain Cys_Met_Meta_PP PF01053.20 EJS43093.1 - 2e-24 85.8 0.0 4.5e-24 84.7 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EJS43093.1 - 0.0039 16.4 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II PDE6_gamma PF04868.12 EJS43093.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit IBN_N PF03810.19 EJS43094.1 - 5.9e-17 61.3 0.0 1.2e-14 54.0 0.0 3.7 3 0 0 3 3 3 2 Importin-beta N-terminal domain Pribosyltran PF00156.27 EJS43095.1 - 1.8e-10 40.6 0.0 2.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TMF_TATA_bd PF12325.8 EJS43096.1 - 2.7e-32 111.4 20.8 2.7e-32 111.4 20.8 6.0 2 1 3 6 6 5 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EJS43096.1 - 6.7e-16 58.0 7.9 6.7e-16 58.0 7.9 9.3 5 3 5 10 10 9 1 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 EJS43096.1 - 0.0015 18.2 21.8 0.0015 18.2 21.8 4.6 3 1 1 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 EJS43096.1 - 0.0065 16.5 10.0 0.0065 16.5 10.0 7.3 2 2 5 8 8 8 1 Protein of unknown function (DUF1664) FadA PF09403.10 EJS43096.1 - 0.0073 16.8 8.5 0.0073 16.8 8.5 8.0 4 2 2 7 7 7 1 Adhesion protein FadA EzrA PF06160.12 EJS43096.1 - 0.015 13.5 71.7 0.041 12.1 13.9 3.2 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA DUF3584 PF12128.8 EJS43096.1 - 0.17 9.4 64.2 0.13 9.7 41.9 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) HMMR_N PF15905.5 EJS43096.1 - 0.8 9.1 82.0 0.026 14.0 28.7 4.2 3 1 1 4 4 4 0 Hyaluronan mediated motility receptor N-terminal DUF812 PF05667.11 EJS43096.1 - 2.3 7.0 75.5 0.012 14.5 27.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 EJS43096.1 - 3.5 6.9 49.9 2.6 7.3 8.5 4.8 2 1 3 5 5 5 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 EJS43096.1 - 6.2 6.9 77.3 0.098 12.7 19.9 5.9 2 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein DUF3294 PF07957.11 EJS43097.1 - 0.016 15.0 1.1 0.17 11.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3294) 7TMR-HDED PF07697.11 EJS43097.1 - 0.028 14.5 0.5 0.043 13.9 0.5 1.2 1 0 0 1 1 1 0 7TM-HD extracellular DUF5082 PF16888.5 EJS43097.1 - 0.36 11.1 4.4 6.2 7.1 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) zf-Tim10_DDP PF02953.15 EJS43098.1 - 5.6e-21 74.0 1.8 7.1e-21 73.6 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tti2 PF10521.9 EJS43099.1 - 2.1e-64 217.8 1.3 2.8e-64 217.4 1.3 1.2 1 0 0 1 1 1 1 Tti2 family NIR_SIR PF01077.22 EJS43100.1 - 5.6e-60 201.4 0.0 2.8e-57 192.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 EJS43100.1 - 1.9e-29 102.7 0.0 4e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 EJS43100.1 - 3e-27 94.2 0.1 4.4e-13 48.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain 2H-phosphodiest PF08975.10 EJS43100.1 - 0.07 13.1 0.0 1.9 8.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1868) IML1 PF12257.8 EJS43101.1 - 1.6e-105 352.3 1.1 2.7e-105 351.6 1.1 1.4 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EJS43101.1 - 1.4e-25 89.1 0.7 3.8e-25 87.7 0.7 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Homoserine_dh PF00742.19 EJS43102.1 - 3.5e-52 176.8 0.1 4.9e-52 176.4 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EJS43102.1 - 7.5e-30 104.0 0.0 2.2e-29 102.5 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain DUF5101 PF17031.5 EJS43102.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) DUF4743 PF15916.5 EJS43104.1 - 2.6e-08 33.9 0.1 3.9e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EJS43104.1 - 4.2e-06 26.8 0.0 9.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain PMT PF02366.18 EJS43105.1 - 1.3e-86 290.2 22.5 2.6e-86 289.2 22.5 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EJS43105.1 - 2.4e-63 213.4 8.1 2.4e-63 213.4 8.1 3.8 3 1 0 3 3 3 2 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EJS43105.1 - 1e-21 77.6 0.4 1.9e-21 76.8 0.4 1.4 1 0 0 1 1 1 1 MIR domain PHO4 PF01384.20 EJS43105.1 - 0.025 13.6 0.8 0.11 11.5 0.1 2.1 2 0 0 2 2 2 0 Phosphate transporter family Mgm101p PF06420.12 EJS43106.1 - 9.2e-87 288.9 0.0 1.2e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 HSF_DNA-bind PF00447.17 EJS43107.1 - 2.9e-18 66.3 0.7 2.9e-18 66.3 0.7 2.3 2 1 0 2 2 2 1 HSF-type DNA-binding XhlA PF10779.9 EJS43107.1 - 0.024 14.9 0.3 0.043 14.0 0.3 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Cortex-I_coil PF09304.10 EJS43107.1 - 0.1 12.8 0.5 0.18 12.0 0.2 1.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil P4Ha_N PF08336.11 EJS43107.1 - 0.19 11.8 2.6 0.33 11.0 2.6 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TFIIA PF03153.13 EJS43107.1 - 0.21 11.5 8.9 0.28 11.1 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EJS43107.1 - 0.32 11.6 6.6 0.73 10.5 6.6 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 EJS43107.1 - 2 8.4 8.3 3.1 7.8 8.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MgsA_C PF12002.8 EJS43107.1 - 2.7 7.9 5.0 4.7 7.1 5.0 1.4 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Aminotran_4 PF01063.19 EJS43108.1 - 6.4e-35 121.0 0.0 7.9e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV SRP1_TIP1 PF00660.17 EJS43109.1 - 3.1e-25 88.1 0.0 9.8e-25 86.5 0.0 1.9 1 0 0 1 1 1 1 Seripauperin and TIP1 family SOG2 PF10428.9 EJS43109.1 - 0.09 12.0 25.4 0.12 11.6 25.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Plasmodium_Vir PF05795.11 EJS43109.1 - 3.7 6.9 9.7 5 6.4 9.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DHHW PF14286.6 EJS43109.1 - 6.8 5.9 13.7 11 5.2 13.7 1.4 1 0 0 1 1 1 0 DHHW protein FAD_binding_2 PF00890.24 EJS43110.1 - 2.6e-121 405.6 3.0 3.1e-121 405.3 3.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EJS43110.1 - 1.8e-44 150.8 0.5 2.7e-44 150.2 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EJS43110.1 - 1e-05 24.8 0.3 0.0032 16.6 0.3 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EJS43110.1 - 0.00015 21.1 0.0 0.00057 19.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJS43110.1 - 0.00056 19.2 0.1 0.057 12.6 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EJS43110.1 - 0.0032 16.8 0.1 0.0087 15.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EJS43110.1 - 0.02 14.5 1.3 0.078 12.6 1.2 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EJS43110.1 - 0.054 12.2 0.1 0.26 10.0 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein Eaf7 PF07904.13 EJS43111.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 Nup192 PF11894.8 EJS43112.1 - 0 1691.2 50.7 0 1691.0 50.7 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF2508 PF10704.9 EJS43112.1 - 0.065 13.4 0.2 0.41 10.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DUF1344 PF07076.11 EJS43112.1 - 0.076 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DUF4114 PF13448.6 EJS43112.1 - 0.12 13.2 0.6 0.59 11.0 0.6 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) RPM2 PF08579.11 EJS43112.1 - 2.5 8.5 6.7 1.1 9.7 1.5 3.1 2 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) L31 PF09784.9 EJS43113.1 - 0.01 16.2 1.2 0.031 14.7 0.4 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 PAH PF02671.21 EJS43113.1 - 0.11 12.6 0.1 0.44 10.7 0.1 1.9 2 0 0 2 2 2 0 Paired amphipathic helix repeat GHL13 PF14883.6 EJS43113.1 - 0.14 11.2 0.1 0.21 10.6 0.0 1.3 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 Drf_GBD PF06371.13 EJS43114.1 - 0.003 17.1 0.6 0.0047 16.5 0.6 1.3 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF2207 PF09972.9 EJS43114.1 - 0.015 14.1 0.3 0.02 13.7 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PX PF00787.24 EJS43115.1 - 6.9e-26 90.5 0.2 2.1e-25 88.9 0.2 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EJS43115.1 - 4.1e-05 23.2 13.4 0.0001 22.0 2.2 2.2 2 0 0 2 2 2 2 Vps5 C terminal like ATG16 PF08614.11 EJS43115.1 - 0.016 15.5 3.8 0.92 9.7 0.8 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 EJS43115.1 - 0.031 14.3 1.7 0.36 10.9 0.1 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RPW8 PF05659.11 EJS43115.1 - 0.037 13.7 1.0 0.037 13.7 1.0 3.2 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DASH_Dam1 PF08653.10 EJS43115.1 - 0.052 13.4 0.7 12 5.8 0.1 3.4 1 1 1 2 2 2 0 DASH complex subunit Dam1 DUF1664 PF07889.12 EJS43115.1 - 0.11 12.5 7.8 0.19 11.8 2.9 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EJS43115.1 - 0.12 12.8 4.3 9.6 6.8 2.4 3.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EJS43115.1 - 0.19 12.2 5.8 9.7 6.7 0.5 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 EJS43115.1 - 0.34 10.8 3.0 0.31 10.9 0.7 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ABC_tran_CTD PF16326.5 EJS43115.1 - 0.39 11.0 4.8 16 5.9 0.5 3.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF4407 PF14362.6 EJS43115.1 - 0.41 9.9 2.5 7.4 5.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4391 PF14335.6 EJS43115.1 - 0.47 10.1 8.0 0.067 12.9 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) TMPIT PF07851.13 EJS43115.1 - 0.67 9.1 9.2 0.14 11.4 2.5 2.3 1 1 0 2 2 2 0 TMPIT-like protein ING PF12998.7 EJS43115.1 - 0.67 10.6 7.1 0.18 12.4 1.9 2.5 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding T3SSipB PF16535.5 EJS43115.1 - 0.77 10.2 4.3 0.61 10.6 0.6 2.3 2 1 0 2 2 2 0 Type III cell invasion protein SipB BRE1 PF08647.11 EJS43115.1 - 0.9 9.7 15.0 0.82 9.8 5.1 3.4 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase TMF_TATA_bd PF12325.8 EJS43115.1 - 0.92 9.7 11.9 1 9.6 0.7 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sec34 PF04136.15 EJS43115.1 - 1.7 8.5 10.4 0.29 11.0 4.6 2.3 2 1 0 2 2 2 0 Sec34-like family PhoU PF01895.19 EJS43115.1 - 2 8.9 7.4 0.65 10.5 0.4 3.1 2 1 1 3 3 3 0 PhoU domain DUF4618 PF15397.6 EJS43115.1 - 2.2 7.6 18.7 0.076 12.4 5.9 3.1 2 2 2 4 4 4 0 Domain of unknown function (DUF4618) DUF948 PF06103.11 EJS43115.1 - 3.3 8.0 7.2 3 8.2 1.0 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) GreA_GreB_N PF03449.15 EJS43115.1 - 3.6 7.8 6.1 19 5.5 0.3 4.2 5 0 0 5 5 5 0 Transcription elongation factor, N-terminal DUF3552 PF12072.8 EJS43115.1 - 4 6.8 9.8 0.97 8.8 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) bZIP_1 PF00170.21 EJS43115.1 - 4.3 7.5 9.7 27 4.9 0.7 3.6 2 1 1 3 3 3 0 bZIP transcription factor BST2 PF16716.5 EJS43115.1 - 8.4 7.1 9.6 3.5 8.3 0.4 3.4 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 dCMP_cyt_deam_1 PF00383.23 EJS43116.1 - 1.7e-22 79.2 0.2 2.3e-22 78.8 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EJS43116.1 - 1.6e-15 57.1 0.0 2.3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EJS43116.1 - 0.00052 20.1 0.4 0.057 13.5 0.4 2.3 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.11 EJS43116.1 - 0.00097 19.1 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 EJS43116.1 - 0.002 18.3 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 SNAD4 PF18750.1 EJS43116.1 - 0.0057 16.8 0.0 0.0098 16.0 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EJS43116.1 - 0.023 14.7 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 APOBEC2 APOBEC3 PF18771.1 EJS43116.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 DUF3525 PF12039.8 EJS43116.1 - 0.16 10.7 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) HSP70 PF00012.20 EJS43117.1 - 3.2e-261 867.8 12.4 3.6e-261 867.6 12.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJS43117.1 - 3.4e-18 65.6 1.7 7.9e-17 61.1 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EJS43117.1 - 0.0012 19.2 4.9 1.2 9.5 0.2 3.8 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 EJS43117.1 - 0.0052 16.1 2.5 0.15 11.3 0.0 3.3 2 1 0 3 3 3 1 Hydantoinase/oxoprolinase Radial_spoke_3 PF06098.11 EJS43117.1 - 0.0072 15.6 0.9 0.014 14.7 0.9 1.4 1 0 0 1 1 1 1 Radial spoke protein 3 BcrAD_BadFG PF01869.20 EJS43117.1 - 0.018 14.5 0.4 1.4 8.4 0.1 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DEAD PF00270.29 EJS43118.1 - 2e-47 161.2 0.2 7.1e-47 159.4 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS43118.1 - 1.3e-25 89.9 0.0 5.3e-25 87.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EJS43118.1 - 2.5e-20 72.4 0.0 5.4e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EJS43118.1 - 2.1e-08 34.4 0.0 2.1e-08 34.4 0.0 2.5 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EJS43118.1 - 0.026 13.9 0.1 0.026 13.9 0.1 3.3 3 1 1 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit HORMA PF02301.18 EJS43119.1 - 9.3e-23 80.9 0.1 1.8e-22 80.0 0.1 1.4 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EJS43119.1 - 0.0033 17.4 0.2 0.024 14.6 0.2 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 bacHORMA_2 PF18173.1 EJS43119.1 - 0.0093 15.8 0.3 0.042 13.7 0.0 2.1 2 1 0 2 2 2 1 Bacterial HORMA domain 2 ATG13 PF10033.9 EJS43119.1 - 0.029 14.1 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 13 V-set_CD47 PF08204.11 EJS43119.1 - 0.091 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Vps53_N PF04100.12 EJS43120.1 - 1.5e-112 376.3 15.0 2.5e-112 375.6 15.0 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 EJS43120.1 - 1.2e-84 283.3 1.2 2.3e-84 282.3 1.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 53 C-terminus DivIVA PF05103.13 EJS43120.1 - 0.024 14.7 0.8 2.6 8.1 0.2 2.9 2 0 0 2 2 2 0 DivIVA protein SSFA2_C PF14723.6 EJS43120.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF2383 PF09537.10 EJS43120.1 - 0.064 13.6 0.0 2.3 8.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) DUF1664 PF07889.12 EJS43120.1 - 0.2 11.7 0.6 0.85 9.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribonuc_red_sm PF00268.21 EJS43121.1 - 5.3e-115 383.7 1.6 8.3e-115 383.0 1.6 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.10 EJS43121.1 - 0.026 13.8 0.4 5.4 6.2 0.0 2.2 2 0 0 2 2 2 0 XcyI restriction endonuclease Exonuc_VII_L PF02601.15 EJS43121.1 - 0.055 13.0 1.1 0.072 12.6 1.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4744 PF15918.5 EJS43121.1 - 0.085 13.7 0.0 0.2 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) GIDA_assoc PF13932.6 EJS43121.1 - 0.94 9.6 6.2 1.6 8.9 6.2 1.3 1 0 0 1 1 1 0 GidA associated domain YtxH PF12732.7 EJS43121.1 - 1.2 9.8 3.3 2.7 8.6 3.3 1.6 1 0 0 1 1 1 0 YtxH-like protein zf-RRN7 PF11781.8 EJS43122.1 - 6.8e-10 38.5 0.5 1.3e-09 37.6 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF5083 PF16890.5 EJS43122.1 - 0.082 12.6 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) Lipoprotein_10 PF03202.13 EJS43122.1 - 0.35 11.3 8.1 0.18 12.2 2.4 2.9 3 0 0 3 3 3 0 Putative mycoplasma lipoprotein, C-terminal region SH3_1 PF00018.28 EJS43123.1 - 6.1e-08 32.1 0.4 1.7e-07 30.7 0.4 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EJS43123.1 - 5.2e-07 29.2 0.0 1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EJS43123.1 - 0.003 17.4 0.2 0.0064 16.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain Sad1_UNC PF07738.13 EJS43124.1 - 3.8e-05 23.7 7.8 0.0001 22.3 0.2 3.7 4 1 0 4 4 4 1 Sad1 / UNC-like C-terminal DUF1664 PF07889.12 EJS43124.1 - 0.0094 16.0 7.4 0.3 11.1 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Myb_DNA-bind_5 PF13873.6 EJS43124.1 - 0.25 11.4 2.5 1.7 8.8 0.7 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SAPIS-gp6 PF16722.5 EJS43124.1 - 0.79 10.2 10.4 0.085 13.3 5.1 2.1 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus YabA PF06156.13 EJS43124.1 - 1.6 9.4 12.9 0.35 11.5 0.9 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 EJS43124.1 - 2.4 8.2 9.0 0.16 12.0 3.4 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.6 EJS43124.1 - 6.6 6.8 32.1 0.11 12.5 3.9 3.5 3 0 0 3 3 3 0 FlxA-like protein Pollen_Ole_e_I PF01190.17 EJS43125.1 - 0.056 13.8 0.2 0.18 12.2 0.2 1.9 1 0 0 1 1 1 0 Pollen proteins Ole e I like Mad3_BUB1_I PF08311.12 EJS43126.1 - 7.3e-38 129.3 0.3 1.2e-37 128.7 0.3 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 EJS43126.1 - 6.6e-27 93.5 0.3 2.5e-26 91.6 0.0 2.2 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 EJS43126.1 - 2.2e-06 27.8 1.4 5.1e-06 26.6 1.4 1.6 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein VTC PF09359.10 EJS43127.1 - 1.8e-101 339.1 1.0 2e-101 339.0 0.2 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 EJS43127.1 - 4.7e-11 43.2 13.2 4.9e-06 26.7 0.6 3.9 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 EJS43127.1 - 5.2e-09 36.4 3.9 5.4e-09 36.4 2.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TFIIF_alpha PF05793.12 EJS43127.1 - 0.041 12.5 0.8 0.076 11.6 0.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_Rpb4 PF03874.16 EJS43128.1 - 2.9e-33 114.8 4.4 3.3e-33 114.6 4.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1980 PF09323.10 EJS43128.1 - 0.1 12.5 1.6 0.14 12.0 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Smoothelin PF12510.8 EJS43128.1 - 0.12 12.5 0.9 0.26 11.4 0.1 2.1 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein RET_CLD3 PF17812.1 EJS43129.1 - 0.0043 17.3 0.1 0.023 15.0 0.1 2.3 1 0 0 1 1 1 1 RET Cadherin like domain 3 Mdv1 PF11542.8 EJS43130.1 - 2.4e-34 117.0 0.9 2.4e-34 117.0 0.9 2.1 2 0 0 2 2 2 1 Mitochondrial division protein 1 WD40 PF00400.32 EJS43130.1 - 2.6e-33 113.5 7.9 1.4e-07 32.0 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 EJS43130.1 - 4.4e-10 38.8 7.7 0.0003 19.6 0.4 5.2 1 1 4 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EJS43130.1 - 5.6e-10 39.4 0.0 0.012 15.9 0.0 4.6 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EJS43130.1 - 0.00036 20.0 0.0 0.017 14.5 0.0 3.1 1 1 2 3 3 3 1 WD40-like domain PQQ_2 PF13360.6 EJS43130.1 - 0.022 14.3 0.2 0.053 13.1 0.1 1.7 2 0 0 2 2 2 0 PQQ-like domain SOAR PF16533.5 EJS43130.1 - 0.031 14.2 0.2 0.13 12.3 0.2 2.0 1 0 0 1 1 1 0 STIM1 Orai1-activating region DUF16 PF01519.16 EJS43130.1 - 0.049 14.1 0.8 0.11 12.9 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 EJS43130.1 - 0.12 12.4 0.6 0.3 11.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 EJS43130.1 - 0.57 10.7 8.6 1.4 9.4 8.6 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region BP28CT PF08146.12 EJS43131.1 - 1.1e-35 122.8 2.4 1.1e-35 122.8 2.4 3.6 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EJS43131.1 - 1.3e-20 73.9 3.0 1.3e-20 73.9 3.0 5.5 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 EJS43131.1 - 0.0039 17.5 0.6 10 6.6 0.0 5.5 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.22 EJS43131.1 - 0.045 14.0 0.4 21 5.7 0.1 4.7 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.6 EJS43131.1 - 0.055 14.0 1.2 25 5.5 0.3 3.7 3 0 0 3 3 3 0 HEAT-like repeat IFT20 PF14931.6 EJS43131.1 - 0.14 12.3 0.1 0.14 12.3 0.1 3.5 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 ThrE PF06738.12 EJS43132.1 - 2.1e-54 184.5 14.3 2.6e-49 167.8 3.0 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EJS43132.1 - 1.5e-11 44.5 28.4 2.8e-11 43.7 9.3 2.1 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Peptidase_A8 PF01252.18 EJS43132.1 - 0.33 11.2 4.8 0.1 12.9 0.5 2.2 2 1 2 4 4 4 0 Signal peptidase (SPase) II DUF2530 PF10745.9 EJS43132.1 - 1.4 9.2 4.6 8.6 6.7 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Pkinase PF00069.25 EJS43133.1 - 6.3e-54 183.1 0.2 4.4e-52 177.0 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43133.1 - 2.6e-27 95.8 0.5 2.1e-25 89.5 0.1 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EJS43133.1 - 1.3e-05 24.4 2.6 1.4e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 EJS43133.1 - 0.07 12.5 0.2 0.15 11.4 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pam16 PF03656.13 EJS43134.1 - 9.8e-57 190.5 0.9 1.1e-56 190.2 0.9 1.0 1 0 0 1 1 1 1 Pam16 Zn_clus PF00172.18 EJS43135.1 - 4.1e-07 30.0 13.4 8.6e-07 29.0 13.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EJS43135.1 - 0.064 13.3 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 PAS fold GTP_EFTU PF00009.27 EJS43136.1 - 1.2e-59 201.2 0.1 1.9e-59 200.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EJS43136.1 - 1e-26 92.8 0.0 2.3e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EJS43136.1 - 1.5e-16 60.2 0.0 5.9e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EJS43136.1 - 1e-10 41.8 0.1 2.4e-10 40.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EJS43136.1 - 2.9e-05 23.9 0.0 5.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EJS43136.1 - 0.0088 16.1 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase VWA_N2 PF16164.5 EJS43136.1 - 0.073 13.2 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 VWA N-terminal PI3_PI4_kinase PF00454.27 EJS43137.1 - 1.3e-74 251.2 0.0 1.9e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ChAPs PF09295.10 EJS43138.1 - 1.1e-46 159.7 4.1 2.8e-38 132.0 1.5 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 EJS43138.1 - 9.4e-07 29.0 1.5 1e-05 25.7 0.3 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EJS43138.1 - 4.6e-05 23.2 0.4 0.079 13.1 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EJS43138.1 - 0.0017 18.1 0.7 0.011 15.5 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJS43138.1 - 0.0071 16.8 0.0 0.038 14.5 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EJS43138.1 - 0.2 11.8 0.0 0.77 9.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EJS43138.1 - 0.72 10.2 4.7 0.54 10.6 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SAPS PF04499.15 EJS43139.1 - 3.2e-176 586.9 12.2 3.2e-176 586.9 12.2 3.4 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Ribosomal_L21p PF00829.21 EJS43140.1 - 4.2e-11 43.0 0.1 5.5e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ion_trans_2 PF07885.16 EJS43141.1 - 5.7e-28 96.7 34.6 7.1e-18 64.4 7.5 3.8 4 0 0 4 4 4 2 Ion channel Ion_trans PF00520.31 EJS43141.1 - 0.099 11.8 28.2 0.54 9.5 4.1 3.4 2 1 0 2 2 2 0 Ion transport protein GWT1 PF06423.12 EJS43142.1 - 1e-39 136.1 2.7 1e-39 136.1 2.7 2.5 3 1 1 4 4 4 1 GWT1 DUF4818 PF16089.5 EJS43142.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4818) BRCT PF00533.26 EJS43143.1 - 8.6e-24 83.7 12.7 4.5e-11 43.0 0.2 5.1 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EJS43143.1 - 1.4e-20 73.5 7.6 2.2e-09 37.6 0.1 4.1 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EJS43143.1 - 7.7e-10 38.6 0.2 7.8e-06 25.7 0.0 4.3 5 0 0 5 5 5 2 twin BRCT domain T6SS_VasJ PF16989.5 EJS43143.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ RTT107_BRCT_5 PF16770.5 EJS43143.1 - 0.27 11.1 2.6 3.3 7.6 0.3 3.9 5 0 0 5 5 5 0 Regulator of Ty1 transposition protein 107 BRCT domain Zn_clus PF00172.18 EJS43144.1 - 3.9e-11 42.9 11.1 6.1e-11 42.3 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_lig_T4_1 PF09511.10 EJS43145.1 - 1.5e-79 266.9 0.6 4.1e-79 265.5 0.0 2.1 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.11 EJS43145.1 - 1.2e-74 250.0 0.4 1.2e-74 250.0 0.4 2.4 3 0 0 3 3 3 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 EJS43145.1 - 1.8e-60 204.5 2.0 2.5e-60 204.1 2.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain ABC_tran PF00005.27 EJS43145.1 - 0.038 14.5 0.1 0.12 12.9 0.1 1.9 1 0 0 1 1 1 0 ABC transporter Exo70 PF03081.15 EJS43146.1 - 1.8e-86 290.6 9.0 1.8e-86 290.6 9.0 2.2 2 0 0 2 2 2 2 Exo70 exocyst complex subunit FEZ PF07763.13 EJS43146.1 - 0.034 13.9 2.3 0.035 13.8 0.7 1.8 2 0 0 2 2 2 0 FEZ-like protein Arrestin_C PF02752.22 EJS43147.1 - 1.1e-14 55.0 4.2 1.7e-14 54.4 0.1 2.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EJS43147.1 - 1.3e-07 31.8 6.1 1.1e-06 28.8 0.1 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain EF-hand_4 PF12763.7 EJS43148.1 - 0.0007 19.5 0.1 0.0018 18.2 0.1 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF3808 PF10300.9 EJS43149.1 - 1.5e-163 545.0 0.0 1.8e-163 544.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Parathyroid PF01279.17 EJS43149.1 - 0.037 14.6 0.1 2.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Parathyroid hormone family Actin PF00022.19 EJS43150.1 - 1.3e-97 327.0 0.0 1.6e-96 323.4 0.0 1.9 1 1 0 1 1 1 1 Actin KH_1 PF00013.29 EJS43151.1 - 8.9e-85 278.5 37.4 2.5e-13 49.6 1.4 12.5 12 0 0 12 12 12 9 KH domain KH_2 PF07650.17 EJS43151.1 - 1.4e-12 47.2 22.8 0.00013 21.7 0.7 7.1 5 1 1 6 6 6 4 KH domain KH_4 PF13083.6 EJS43151.1 - 2e-07 30.8 4.0 0.69 9.8 0.0 6.2 4 1 0 4 4 4 3 KH domain SLS PF14611.6 EJS43151.1 - 0.00012 22.0 25.2 0.048 13.5 0.1 7.5 4 3 2 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 EJS43151.1 - 0.00073 19.6 19.4 0.88 9.7 0.1 7.4 7 0 0 7 7 7 2 NusA-like KH domain EMP24_GP25L PF01105.24 EJS43151.1 - 0.2 11.6 0.0 0.2 11.6 0.0 3.2 4 1 0 4 4 4 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.12 EJS43151.1 - 4.3 7.4 10.2 12 6.0 0.2 4.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) CAP PF00188.26 EJS43152.1 - 1.3e-19 71.2 1.2 1.3e-19 71.2 1.2 2.4 2 0 0 2 2 2 1 Cysteine-rich secretory protein family BNIP3 PF06553.12 EJS43152.1 - 0.019 14.7 5.2 0.024 14.3 5.2 1.1 1 0 0 1 1 1 0 BNIP3 DUF3306 PF11748.8 EJS43152.1 - 0.19 12.6 7.2 0.4 11.6 7.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) DUF5427 PF10310.9 EJS43152.1 - 0.24 10.3 6.7 0.31 10.0 6.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Dicty_REP PF05086.12 EJS43152.1 - 0.68 7.8 6.3 0.87 7.5 6.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SWI-SNF_Ssr4 PF08549.10 EJS43152.1 - 1.1 7.8 8.2 1.4 7.5 8.2 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SMYLE_N PF18615.1 EJS43152.1 - 1.9 8.0 8.2 2.6 7.5 8.2 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Hamartin PF04388.12 EJS43152.1 - 2.6 6.6 10.5 3 6.4 10.5 1.0 1 0 0 1 1 1 0 Hamartin protein FAM199X PF15814.5 EJS43152.1 - 9 5.3 13.2 13 4.7 13.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X CAP PF00188.26 EJS43153.1 - 1.3e-19 71.3 2.4 1.3e-19 71.3 2.4 4.5 6 0 0 6 6 6 1 Cysteine-rich secretory protein family Cytokin_check_N PF10407.9 EJS43154.1 - 2.3e-31 107.6 3.0 5.8e-31 106.3 3.0 1.8 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus SMC_N PF02463.19 EJS43155.1 - 5.3e-54 183.0 56.9 3.9e-53 180.1 56.9 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EJS43155.1 - 1.3e-28 99.6 0.0 6.5e-28 97.4 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EJS43155.1 - 1.4e-15 57.9 11.6 9.5e-10 38.8 0.6 3.6 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EJS43155.1 - 1.1e-12 48.4 18.3 1.1e-12 48.4 18.3 4.6 2 2 3 5 5 5 2 AAA ATPase domain AAA_29 PF13555.6 EJS43155.1 - 0.0066 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3869 PF12985.7 EJS43155.1 - 0.29 11.5 2.5 0.55 10.6 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3869) AAA_23 PF13476.6 EJS43155.1 - 0.43 11.1 133.6 0.74 10.3 62.5 7.8 1 1 2 3 3 3 0 AAA domain DnaJ PF00226.31 EJS43156.1 - 3.7e-21 75.0 5.0 1e-20 73.6 5.0 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_8 PF13181.6 EJS43156.1 - 0.022 14.9 0.0 0.38 11.1 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIA PF03153.13 EJS43156.1 - 0.088 12.8 12.3 0.13 12.3 12.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sld5 PF05916.11 EJS43157.1 - 2e-19 70.1 1.7 4.1e-19 69.1 1.7 1.5 1 0 0 1 1 1 1 GINS complex protein A_deaminase PF00962.22 EJS43158.1 - 1.1e-27 97.3 0.0 6.4e-14 52.0 0.0 3.8 4 1 0 4 4 4 3 Adenosine/AMP deaminase DUF1419 PF07215.11 EJS43158.1 - 0.066 13.3 0.0 16 5.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) WD40 PF00400.32 EJS43159.1 - 1.3e-14 54.4 0.1 6.6e-05 23.6 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS43159.1 - 6.5e-10 39.2 0.0 0.023 15.0 0.0 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Esterase PF00756.20 EJS43160.1 - 6.7e-70 235.6 0.2 7.6e-70 235.4 0.2 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EJS43160.1 - 0.0024 17.4 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family MPM1 PF17234.2 EJS43161.1 - 9.4e-37 126.9 0.0 1.4e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 CBFD_NFYB_HMF PF00808.23 EJS43162.1 - 6e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2920 PF11144.8 EJS43162.1 - 0.076 12.2 0.1 0.096 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Mrpl_C PF18502.1 EJS43163.1 - 3.5e-34 117.4 0.2 7.7e-34 116.3 0.2 1.6 1 0 0 1 1 1 1 54S ribosomal protein L8 C-terminal domain Ribosomal_L17 PF01196.19 EJS43163.1 - 1.6e-29 102.6 0.1 6.2e-29 100.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 mIF3 PF14877.6 EJS43163.1 - 0.047 13.4 0.2 0.092 12.4 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Phosphodiest PF01663.22 EJS43165.1 - 4.7e-12 46.2 5.3 1.5e-09 38.0 5.3 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EJS43165.1 - 0.00031 20.2 0.1 0.00056 19.4 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EJS43165.1 - 0.02 14.3 0.4 0.037 13.4 0.4 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily SLATT_1 PF18181.1 EJS43165.1 - 1.6 8.6 3.8 0.65 9.9 0.4 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Aminotran_1_2 PF00155.21 EJS43166.1 - 7e-92 308.4 0.0 8.2e-92 308.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EJS43166.1 - 3.9e-05 23.1 0.0 7.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EJS43166.1 - 0.00024 19.8 0.3 0.0009 17.9 0.3 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EJS43166.1 - 0.00071 18.6 0.1 0.003 16.6 0.1 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.21 EJS43166.1 - 0.0017 17.1 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III DUF2240 PF09999.9 EJS43166.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) Beta_elim_lyase PF01212.21 EJS43166.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase CLN3 PF02487.17 EJS43167.1 - 4.9e-145 483.6 16.0 6e-145 483.3 16.0 1.1 1 0 0 1 1 1 1 CLN3 protein PrgI PF12666.7 EJS43167.1 - 0.033 14.9 0.1 0.033 14.9 0.1 3.1 4 0 0 4 4 4 0 PrgI family protein Pex24p PF06398.11 EJS43167.1 - 1 8.3 5.0 0.1 11.6 0.4 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin HbrB PF08539.11 EJS43168.1 - 7.2e-33 114.0 0.2 7.2e-33 114.0 0.2 1.9 2 0 0 2 2 2 1 HbrB-like Imm48 PF15574.6 EJS43168.1 - 0.046 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 48 Pkinase PF00069.25 EJS43169.1 - 6.6e-32 110.9 0.0 4e-31 108.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43169.1 - 1.7e-18 66.9 0.0 1.2e-17 64.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJS43169.1 - 0.0034 16.2 0.0 0.0051 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EJS43169.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EJS43169.1 - 0.031 13.9 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-C2H2 PF00096.26 EJS43170.1 - 2.4e-21 74.9 76.0 1.4e-05 25.2 1.0 9.4 11 0 0 11 11 9 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EJS43170.1 - 5.8e-21 73.9 52.0 1.3e-07 31.7 0.3 8.4 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJS43170.1 - 3e-15 55.6 67.6 0.00017 22.1 0.9 9.7 9 0 0 9 9 9 7 C2H2-type zinc finger Zap1_zf2 PF18217.1 EJS43170.1 - 2.1e-10 40.4 8.1 2.1e-10 40.4 8.1 4.8 4 0 0 4 4 4 1 Zap1 zinc finger 2 FOXP-CC PF16159.5 EJS43170.1 - 2.2e-06 28.2 35.0 0.00071 20.2 0.7 7.0 5 2 3 8 8 8 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EJS43170.1 - 0.00028 21.1 47.3 0.02 15.2 2.0 7.3 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EJS43170.1 - 0.00028 20.8 46.1 0.11 12.5 1.8 7.1 6 1 1 7 7 7 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EJS43170.1 - 0.012 15.4 0.9 0.012 15.4 0.9 5.5 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 EJS43170.1 - 0.14 12.1 0.2 0.14 12.1 0.2 6.0 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-met PF12874.7 EJS43170.1 - 0.83 10.1 50.8 0.2 12.1 3.2 7.9 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 EJS43170.1 - 2.9 7.6 18.9 2 8.1 0.1 5.5 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger Phage_Orf51 PF06194.11 EJS43170.1 - 3.3 7.8 4.7 49 4.0 0.0 3.1 3 0 0 3 3 3 0 Phage Conserved Open Reading Frame 51 Vps26 PF03643.15 EJS43171.1 - 4.7e-123 409.6 0.3 5.5e-123 409.3 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EJS43171.1 - 0.0018 18.4 0.5 0.014 15.5 0.2 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EJS43171.1 - 0.0036 17.7 0.3 0.015 15.7 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Gp_dh_C PF02800.20 EJS43172.1 - 1.1e-71 239.5 0.0 1.7e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EJS43172.1 - 3.3e-39 133.3 0.1 7.3e-39 132.2 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EJS43172.1 - 0.0042 17.2 0.3 0.024 14.8 0.3 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RTX_C PF08339.10 EJS43172.1 - 0.092 12.8 0.0 0.65 10.0 0.0 2.1 2 0 0 2 2 2 0 RTX C-terminal domain PAP2 PF01569.21 EJS43173.1 - 1.4e-17 63.7 3.3 3.3e-17 62.5 3.3 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EJS43173.1 - 0.00011 22.0 4.2 0.00025 20.8 4.2 1.7 1 0 0 1 1 1 1 PAP2 superfamily Mito_carr PF00153.27 EJS43175.1 - 7.8e-62 205.2 3.6 9.7e-23 79.9 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein mIF3 PF14877.6 EJS43176.1 - 1.8e-64 216.7 13.2 1.8e-64 216.7 13.2 1.8 2 0 0 2 2 2 1 Mitochondrial translation initiation factor CPSase_L_D2 PF02786.17 EJS43177.1 - 2.5e-114 380.1 0.9 4e-83 278.1 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EJS43177.1 - 6.9e-49 164.9 0.0 1.9e-48 163.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EJS43177.1 - 1.1e-45 155.7 0.0 2.6e-45 154.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EJS43177.1 - 5.8e-45 152.9 0.7 1.7e-44 151.4 0.0 2.2 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EJS43177.1 - 5.5e-40 136.5 0.2 1.6e-39 135.0 0.2 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EJS43177.1 - 4.6e-30 104.8 0.0 3.6e-29 101.9 0.0 2.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EJS43177.1 - 4.5e-22 78.1 0.0 2.5e-21 75.7 0.0 2.4 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EJS43177.1 - 2.5e-18 66.3 3.7 8.9e-11 41.7 0.4 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EJS43177.1 - 2.8e-15 56.3 0.8 4.7e-07 29.5 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EJS43177.1 - 7.9e-12 45.1 0.1 1.5e-06 28.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EJS43177.1 - 1.7e-05 25.0 1.6 0.02 14.9 0.2 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EJS43177.1 - 0.0001 22.1 0.0 0.0095 15.7 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.11 EJS43177.1 - 0.00048 19.8 0.3 0.061 12.9 0.1 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.24 EJS43177.1 - 0.003 17.4 0.2 0.61 9.9 0.0 4.2 5 0 0 5 5 5 1 DJ-1/PfpI family GARS_A PF01071.19 EJS43177.1 - 0.014 15.2 0.7 3.3 7.4 0.0 3.0 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NBD_C PF17042.5 EJS43177.1 - 0.097 13.2 0.1 38 4.7 0.0 3.4 2 1 1 3 3 3 0 Nucleotide-binding C-terminal domain TrkA_N PF02254.18 EJS43177.1 - 0.13 12.5 3.7 0.32 11.2 0.1 3.1 4 0 0 4 4 2 0 TrkA-N domain Pkinase PF00069.25 EJS43178.1 - 2.9e-60 203.9 0.0 4e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43178.1 - 4.7e-36 124.4 0.0 6.8e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43178.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EJS43178.1 - 0.00077 18.6 0.1 0.0013 17.9 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EJS43178.1 - 0.016 14.0 0.0 0.016 14.0 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Hep_59 PF07052.11 EJS43178.1 - 3.2 8.6 7.6 1.4 9.7 0.1 3.0 2 1 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 DUF5310 PF17237.2 EJS43179.1 - 1.1e-23 82.9 2.4 1.2e-23 82.7 2.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) zf-H2C2 PF09337.10 EJS43180.1 - 1e-16 60.8 1.5 1.8e-16 60.0 1.5 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EJS43180.1 - 1.7e-09 37.6 0.8 4.9e-09 36.2 0.8 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 EJS43180.1 - 7.4e-06 26.2 0.0 2.6e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family zf-C2H2_3 PF13878.6 EJS43180.1 - 5.4 6.9 7.9 3.2 7.6 0.3 2.6 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO CN_hydrolase PF00795.22 EJS43181.1 - 6.2e-60 202.7 0.0 7e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GCD14 PF08704.10 EJS43182.1 - 4.1e-83 278.8 0.3 3.1e-82 276.0 0.3 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 EJS43182.1 - 0.0016 18.2 0.0 0.0028 17.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 EJS43182.1 - 0.0023 17.7 0.0 0.0075 16.1 0.0 1.9 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Gcd10p PF04189.13 EJS43182.1 - 0.0036 16.4 0.1 0.0087 15.2 0.0 1.6 2 0 0 2 2 2 1 Gcd10p family RrnaAD PF00398.20 EJS43182.1 - 0.0073 15.4 0.0 0.018 14.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EJS43182.1 - 0.016 15.9 0.0 0.044 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EJS43182.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HTH_Crp_2 PF13545.6 EJS43182.1 - 0.12 12.3 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain LSM PF01423.22 EJS43183.1 - 3.1e-16 58.8 0.1 5.9e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 LSM domain Alb1 PF09135.11 EJS43184.1 - 6.1e-18 65.6 8.3 6.1e-18 65.6 8.3 1.9 2 1 0 2 2 2 1 Alb1 Ribul_P_3_epim PF00834.19 EJS43185.1 - 5.1e-68 228.4 0.0 1e-67 227.4 0.0 1.5 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 EJS43185.1 - 0.0055 16.3 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 EJS43185.1 - 0.075 12.8 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 EJS43185.1 - 0.15 11.5 0.0 0.41 10.1 0.0 1.7 1 0 0 1 1 1 0 Histidine biosynthesis protein Pho86 PF11124.8 EJS43186.1 - 9.3e-107 356.8 0.3 1.1e-106 356.6 0.3 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 SUN PF03856.13 EJS43187.1 - 2.3e-100 335.1 13.9 3.2e-100 334.6 13.9 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) ASF1_hist_chap PF04729.13 EJS43188.1 - 8.6e-72 240.1 0.0 1.2e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone BUD22 PF09073.10 EJS43188.1 - 0.3 10.4 38.0 0.33 10.2 38.0 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EJS43188.1 - 0.49 9.8 42.5 0.79 9.1 42.5 1.4 1 0 0 1 1 1 0 SDA1 DUF2201_N PF13203.6 EJS43188.1 - 6.2 6.3 7.9 19 4.8 7.9 1.7 1 1 0 1 1 1 0 Putative metallopeptidase domain DUF2722 PF10846.8 EJS43188.1 - 6.2 5.6 20.5 9.8 5.0 20.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.12 EJS43188.1 - 9.4 4.3 44.2 13 3.8 44.2 1.2 1 0 0 1 1 1 0 Nop14-like family Amidohydro_1 PF01979.20 EJS43189.1 - 2.1e-32 112.8 0.0 2.5e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EJS43189.1 - 5.6e-09 36.0 0.0 9.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family OPT PF03169.15 EJS43190.1 - 1.9e-158 528.9 42.7 2.3e-158 528.6 42.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pex2_Pex12 PF04757.14 EJS43191.1 - 9.1e-19 67.9 0.6 1.3e-18 67.4 0.6 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Fungal_trans PF04082.18 EJS43194.1 - 1.2e-39 136.0 1.3 1.2e-39 136.0 1.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS43194.1 - 4.7e-09 36.2 13.4 8.9e-09 35.3 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 EJS43194.1 - 0.00072 19.6 7.2 0.0016 18.5 7.2 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 POTRA PF07244.15 EJS43194.1 - 0.13 12.9 0.1 0.38 11.4 0.1 1.8 1 0 0 1 1 1 0 Surface antigen variable number repeat TFIIA PF03153.13 EJS43194.1 - 0.28 11.1 12.9 0.56 10.2 12.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec10 PF07393.11 EJS43195.1 - 3.2e-65 220.9 23.4 3.9e-65 220.6 23.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF1981 PF09324.10 EJS43195.1 - 0.027 14.3 2.5 0.11 12.3 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Telomere_reg-2 PF10193.9 EJS43195.1 - 0.066 13.7 2.0 0.24 11.9 2.0 2.0 1 0 0 1 1 1 0 Telomere length regulation protein Surp PF01805.20 EJS43196.1 - 4.9e-16 58.5 0.8 4.5e-08 33.0 0.0 2.9 3 0 0 3 3 3 2 Surp module PRP21_like_P PF12230.8 EJS43196.1 - 0.00023 21.1 10.0 0.00079 19.4 7.0 2.5 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein ECSIT PF06239.11 EJS43196.1 - 0.02 14.0 0.1 0.037 13.2 0.1 1.5 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF3974 PF13120.6 EJS43196.1 - 0.042 14.0 3.9 0.071 13.2 0.1 2.7 2 1 2 4 4 4 0 Domain of unknown function (DUF3974) CRAL_TRIO_2 PF13716.6 EJS43197.1 - 1.4e-29 103.0 0.5 3.3e-29 101.8 0.5 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 EJS43197.1 - 6.8e-09 35.7 0.4 2.3e-08 34.0 0.4 1.8 1 0 0 1 1 1 1 RhoGAP domain DUF3641 PF12345.8 EJS43197.1 - 0.045 13.8 0.2 0.17 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) DUF1140 PF06600.11 EJS43197.1 - 1.7 9.1 8.6 12 6.4 3.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) Aconitase PF00330.20 EJS43198.1 - 5.4e-152 507.0 0.0 6.7e-152 506.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EJS43198.1 - 1.1e-43 148.7 0.0 1.9e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EJS43198.1 - 0.0048 15.7 0.1 0.011 14.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF521) SPX PF03105.19 EJS43199.1 - 9.6e-40 137.7 11.2 3e-20 73.5 2.8 3.0 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 EJS43199.1 - 5.6e-28 98.0 65.8 5.7e-25 88.1 42.1 2.1 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 EJS43199.1 - 2.1e-20 73.2 38.2 2.9e-20 72.8 38.2 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region DctM PF06808.12 EJS43199.1 - 0.00065 18.6 35.7 0.1 11.4 19.4 2.5 1 1 1 2 2 2 2 Tripartite ATP-independent periplasmic transporter, DctM component UCH PF00443.29 EJS43200.1 - 2.2e-84 283.0 0.0 7.4e-83 278.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJS43200.1 - 8.8e-15 55.1 3.3 1.1e-06 28.5 0.1 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EJS43200.1 - 2.8e-07 31.0 0.8 2.3e-06 28.1 0.0 3.1 3 0 0 3 3 3 1 DUSP domain USP7_C2 PF14533.6 EJS43200.1 - 0.05 13.3 0.2 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal zf-RRPl_C4 PF17026.5 EJS43200.1 - 0.1 12.7 0.1 5.9 7.0 0.0 2.7 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF3797 PF12677.7 EJS43200.1 - 0.12 12.3 0.2 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) AAA_22 PF13401.6 EJS43201.1 - 2.7e-11 43.9 0.0 7.5e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EJS43201.1 - 3.3e-10 40.5 0.1 1.8e-09 38.1 0.0 2.2 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJS43201.1 - 3.7e-07 30.7 0.0 6.2e-06 26.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Cdc6_C PF09079.11 EJS43201.1 - 2.6e-06 27.3 0.1 6e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_7 PF12775.7 EJS43201.1 - 0.00062 19.3 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 EJS43201.1 - 0.0008 18.9 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein PIF1 PF05970.14 EJS43201.1 - 0.011 15.0 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase NACHT PF05729.12 EJS43201.1 - 0.014 15.3 0.1 2.5 8.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 EJS43201.1 - 0.02 15.3 0.1 0.05 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 EJS43201.1 - 0.039 12.8 0.0 0.52 9.2 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase EcoR124_C PF12008.8 EJS43201.1 - 0.061 13.0 1.1 0.16 11.6 1.1 1.6 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal AAA_11 PF13086.6 EJS43201.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EJS43201.1 - 0.079 12.1 0.0 0.89 8.7 0.0 2.3 1 1 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 EJS43201.1 - 0.16 11.2 0.0 0.45 9.7 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPT PF03151.16 EJS43202.1 - 7.7e-32 110.8 20.3 1.4e-16 60.7 3.2 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EJS43202.1 - 0.016 15.3 7.3 0.016 15.3 7.3 4.7 3 2 2 5 5 5 0 EamA-like transporter family Ribosomal_S8 PF00410.19 EJS43203.1 - 3.4e-24 85.2 0.1 4.9e-24 84.7 0.1 1.2 1 1 0 1 1 1 1 Ribosomal protein S8 Glyco_transf_34 PF05637.12 EJS43205.1 - 8.8e-67 225.3 0.0 1.2e-66 224.9 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ATP12 PF07542.11 EJS43206.1 - 1.3e-31 109.4 0.0 1.9e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Prefoldin_2 PF01920.20 EJS43207.1 - 1.1e-13 51.1 6.5 1.2e-13 50.9 6.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit PLAC9 PF15205.6 EJS43207.1 - 0.17 12.3 0.1 0.33 11.4 0.0 1.6 2 0 0 2 2 2 0 Placenta-specific protein 9 DUF948 PF06103.11 EJS43207.1 - 0.51 10.6 3.4 1.4 9.3 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ATG27 PF09451.10 EJS43208.1 - 2.1e-53 181.9 1.6 2.4e-53 181.7 1.6 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CrgA PF06781.12 EJS43208.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Cell division protein CrgA m_DGTX_Dc1a_b_c PF17491.2 EJS43208.1 - 0.061 14.0 1.8 8.1 7.2 0.3 2.5 2 0 0 2 2 2 0 Spider Toxins mu-diguetoxin-1 a, b and c SWIRM PF04433.17 EJS43209.1 - 9e-28 96.5 0.3 9e-28 96.5 0.3 2.4 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EJS43209.1 - 4.1e-24 84.4 6.2 1.2e-23 82.8 6.2 1.9 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EJS43209.1 - 4.5e-13 49.2 0.1 1.1e-12 48.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJS43209.1 - 5.2e-09 36.2 0.0 1.9e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EJS43209.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.4 3 0 0 3 3 3 0 Myb DNA-binding like KRE9 PF05390.11 EJS43210.1 - 3.3e-49 165.8 10.8 3.3e-49 165.8 10.8 2.4 2 1 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 EJS43210.1 - 1.1e-12 48.5 1.7 1.1e-12 48.5 1.7 2.9 3 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4124 PF13511.6 EJS43210.1 - 0.12 12.7 5.4 0.52 10.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) PPC PF04151.15 EJS43210.1 - 1.5 9.9 7.4 0.42 11.7 1.8 2.7 2 1 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Rep_fac-A_3 PF08661.11 EJS43211.1 - 2.9e-31 107.9 0.0 3.2e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Peptidase_M20 PF01546.28 EJS43212.1 - 2.4e-42 145.0 0.0 3.4e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJS43212.1 - 3.5e-20 72.0 0.0 6.1e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2401 PF10287.9 EJS43213.1 - 2.3e-85 285.8 2.3 3.9e-85 285.1 2.3 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EJS43213.1 - 2.9e-22 78.9 0.0 7.2e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SRI PF08236.11 EJS43214.1 - 9.5e-23 80.2 5.0 9.5e-23 80.2 5.0 3.0 1 1 1 2 2 2 1 SRI (Set2 Rpb1 interacting) domain WW_1 PF18507.1 EJS43214.1 - 3.3e-18 65.0 3.3 1e-17 63.5 3.3 1.9 1 0 0 1 1 1 1 WW domain SET PF00856.28 EJS43214.1 - 6.2e-18 65.7 0.3 6.2e-18 65.7 0.3 4.0 4 1 0 4 4 4 1 SET domain AWS PF17907.1 EJS43214.1 - 8.4e-16 57.7 10.7 8.4e-16 57.7 10.7 2.0 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 EJS43214.1 - 0.0014 18.6 2.8 0.0018 18.3 0.0 2.7 3 0 0 3 3 3 1 TFIIS helical bundle-like domain TSNR_N PF04705.12 EJS43214.1 - 0.09 12.9 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus Antimicrobial_7 PF08102.11 EJS43214.1 - 0.14 12.5 3.6 11 6.4 0.1 3.2 2 0 0 2 2 2 0 Scorpion antimicrobial peptide WW PF00397.26 EJS43214.1 - 0.17 12.0 0.1 0.37 10.9 0.1 1.5 1 0 0 1 1 1 0 WW domain polyprenyl_synt PF00348.17 EJS43215.1 - 1.2e-97 326.0 0.3 1.5e-97 325.7 0.3 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SHE3 PF17078.5 EJS43215.1 - 0.015 15.0 0.5 0.028 14.2 0.5 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 UcrQ PF02939.16 EJS43216.1 - 6.1e-34 115.8 2.2 7.2e-34 115.6 2.2 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 EJS43216.1 - 0.00042 20.7 0.1 0.00061 20.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Pkinase PF00069.25 EJS43217.1 - 3.3e-39 134.9 0.1 8.6e-38 130.2 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43217.1 - 2.5e-18 66.3 0.0 8.7e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43217.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EJS43217.1 - 0.075 12.4 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJS43217.1 - 0.15 12.0 0.1 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EJS43218.1 - 3e-71 239.9 0.0 3.9e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43218.1 - 3.7e-40 137.8 0.0 5.1e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43218.1 - 7.1e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EJS43218.1 - 0.062 12.9 0.1 2.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EJS43218.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EJS43218.1 - 0.081 12.0 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EJS43218.1 - 0.082 11.8 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF3297 PF11730.8 EJS43218.1 - 0.14 12.0 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Peptidase_C37 PF05416.12 EJS43218.1 - 0.51 8.8 3.8 0.67 8.4 3.8 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase MFS_1 PF07690.16 EJS43219.1 - 2.9e-21 75.8 31.5 1.4e-19 70.2 19.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3099 PF11298.8 EJS43219.1 - 0.11 12.6 0.0 0.71 10.0 0.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) PIR PF00399.19 EJS43221.1 - 9.3e-32 107.9 38.5 4.8e-08 32.4 4.0 4.6 4 0 0 4 4 4 4 Yeast PIR protein repeat SCHIP-1 PF10148.9 EJS43221.1 - 0.14 11.7 0.4 0.64 9.6 0.1 1.9 1 1 1 2 2 2 0 Schwannomin-interacting protein 1 PIR PF00399.19 EJS43222.1 - 1.3e-71 234.8 141.4 1e-08 34.5 7.6 10.0 9 0 0 9 9 9 9 Yeast PIR protein repeat DUF2072 PF09845.9 EJS43222.1 - 0.27 11.5 3.7 0.94 9.7 3.5 2.2 1 1 0 1 1 1 0 Zn-ribbon containing protein KAsynt_C_assoc PF16197.5 EJS43222.1 - 0.58 10.6 3.3 24 5.4 0.9 3.3 1 1 2 3 3 3 0 Ketoacyl-synthetase C-terminal extension DUF421 PF04239.12 EJS43222.1 - 0.86 9.4 2.3 36 4.2 0.3 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF421) TFIIA PF03153.13 EJS43222.1 - 1.2 9.0 27.9 2.1 8.3 27.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIR PF00399.19 EJS43223.1 - 4.7e-06 26.0 9.0 4.7e-06 26.0 9.0 3.3 2 0 0 2 2 2 1 Yeast PIR protein repeat Pol_alpha_B_N PF08418.10 EJS43223.1 - 0.14 12.1 1.8 0.17 11.8 1.8 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PAP1 PF08601.10 EJS43223.1 - 0.32 10.7 9.9 0.4 10.4 9.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 6PF2K PF01591.18 EJS43224.1 - 4.4e-89 297.6 0.2 6.3e-89 297.1 0.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EJS43224.1 - 3e-38 131.5 0.0 4e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EJS43224.1 - 0.00032 20.9 0.0 0.00062 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Vps35 PF03635.17 EJS43225.1 - 3.6e-271 901.9 36.1 4.5e-271 901.6 36.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 NAD_binding_5 PF07994.12 EJS43226.1 - 4.6e-146 486.3 0.0 5.4e-146 486.1 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EJS43226.1 - 1.3e-44 150.9 0.4 2.9e-44 149.8 0.4 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase F-box-like PF12937.7 EJS43227.1 - 7.5e-09 35.4 0.2 2.4e-08 33.7 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJS43227.1 - 0.00029 20.6 0.1 0.0013 18.6 0.1 2.2 1 0 0 1 1 1 1 F-box domain DivIC PF04977.15 EJS43227.1 - 0.11 12.3 0.5 11 5.8 0.1 2.7 2 0 0 2 2 2 0 Septum formation initiator CRAL_TRIO PF00650.20 EJS43230.1 - 1.1e-23 83.7 0.1 3.1e-23 82.3 0.1 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EJS43230.1 - 9.3e-05 22.5 0.3 0.00037 20.6 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Tim17 PF02466.19 EJS43232.1 - 4e-31 107.7 6.0 5e-31 107.3 6.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 EJS43232.1 - 0.03 14.4 7.8 0.14 12.3 1.4 2.5 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III Pkinase PF00069.25 EJS43233.1 - 3e-49 167.8 0.2 1.6e-48 165.4 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43233.1 - 1.4e-20 73.7 0.0 2.3e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EJS43233.1 - 0.0018 17.9 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EJS43233.1 - 0.015 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJS43233.1 - 0.053 13.1 0.0 0.053 13.1 0.0 2.4 2 1 0 3 3 3 0 Choline/ethanolamine kinase RNA_pol_Rpb4 PF03874.16 EJS43234.1 - 2.1e-35 121.7 11.4 1.8e-34 118.7 11.4 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb4 Caldesmon PF02029.15 EJS43234.1 - 0.012 14.4 11.3 0.014 14.2 11.3 1.0 1 0 0 1 1 1 0 Caldesmon Rtf2 PF04641.12 EJS43234.1 - 0.023 14.0 6.7 0.03 13.7 6.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Cellulose_synt PF03552.14 EJS43234.1 - 0.4 9.1 2.0 0.48 8.9 2.0 1.1 1 0 0 1 1 1 0 Cellulose synthase GAGA_bind PF06217.12 EJS43234.1 - 0.47 10.7 6.1 0.62 10.3 6.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family FYDLN_acid PF09538.10 EJS43234.1 - 1.7 9.4 13.1 0.45 11.2 9.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.6 EJS43234.1 - 2.7 7.7 9.1 0.16 11.6 4.1 1.6 2 0 0 2 2 2 0 FAM176 family DUF1754 PF08555.10 EJS43234.1 - 6.4 7.6 13.8 1.1 10.1 9.9 1.8 1 1 1 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Glyco_transf_15 PF01793.16 EJS43235.1 - 2.6e-106 355.6 9.8 3.1e-106 355.3 9.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase MFS_1 PF07690.16 EJS43236.1 - 1.2e-15 57.4 47.6 6.4e-15 54.9 38.7 3.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EJS43236.1 - 8.5e-07 27.8 21.3 1.2e-06 27.3 21.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ydc2-catalyt PF09159.10 EJS43237.1 - 1.3e-21 77.6 0.0 1.4e-21 77.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Peptidase_S24 PF00717.23 EJS43238.1 - 2e-08 34.1 0.1 3.5e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Peptidase S24-like Rep_fac-A_3 PF08661.11 EJS43238.1 - 0.068 13.5 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Replication factor A protein 3 Fungal_trans PF04082.18 EJS43239.1 - 3.8e-32 111.4 3.3 3.8e-32 111.4 3.3 2.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS43239.1 - 8.8e-07 28.9 7.0 1.9e-06 27.9 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_A_exo1 PF01612.20 EJS43239.1 - 0.2 11.4 2.3 0.35 10.5 2.3 1.3 1 0 0 1 1 1 0 3'-5' exonuclease DUF4175 PF13779.6 EJS43239.1 - 2.4 6.0 13.5 3.8 5.3 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF5321 PF17254.2 EJS43240.1 - 0.0026 17.2 0.2 0.0026 17.2 0.2 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5321) BRCT_3 PF18428.1 EJS43240.1 - 0.026 14.6 0.1 0.071 13.2 0.0 1.7 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF961 PF06125.11 EJS43240.1 - 0.062 13.7 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) Apc15p PF05841.11 EJS43241.1 - 3.7e-36 124.7 0.6 3.7e-36 124.7 0.6 2.2 3 0 0 3 3 3 1 Apc15p protein Transp_cyt_pur PF02133.15 EJS43242.1 - 1.1e-180 601.2 36.3 1.3e-180 600.9 36.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Allantoicase PF03561.15 EJS43243.1 - 3.3e-93 309.3 0.2 2.9e-46 157.0 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Asp_Glu_race PF01177.22 EJS43244.1 - 1.1e-05 25.4 0.0 0.043 13.6 0.0 2.1 2 0 0 2 2 2 2 Asp/Glu/Hydantoin racemase SH3_14 PF18343.1 EJS43244.1 - 0.074 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Dda helicase SH3 domain Malate_synthase PF01274.22 EJS43245.1 - 9.8e-225 746.8 0.0 1.2e-224 746.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF1870 PF08965.10 EJS43245.1 - 0.16 12.0 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) Ank_3 PF13606.6 EJS43246.1 - 1.3e-10 40.6 0.3 6.3e-05 23.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EJS43246.1 - 1.6e-10 41.4 0.2 5.1e-10 39.8 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJS43246.1 - 7.9e-10 39.1 0.1 6.4e-09 36.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJS43246.1 - 4.6e-08 33.2 0.1 2.9e-05 24.2 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.24 EJS43246.1 - 8.8e-08 32.1 0.7 3.8e-07 30.1 0.7 2.2 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.30 EJS43246.1 - 1.3e-07 31.7 0.5 0.0058 17.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat RHD_dimer PF16179.5 EJS43246.1 - 0.1 12.6 0.0 0.36 10.9 0.0 2.0 1 0 0 1 1 1 0 Rel homology dimerisation domain AlaDh_PNT_N PF05222.15 EJS43247.1 - 6.5e-31 107.4 0.0 9.5e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EJS43247.1 - 0.042 13.1 0.0 0.25 10.6 0.0 2.1 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EJS43248.1 - 1.2e-49 168.4 0.7 1.4e-49 168.2 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJS43248.1 - 3.2e-30 105.4 0.1 3.9e-30 105.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJS43248.1 - 1.8e-07 31.2 0.0 2.4e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 EJS43248.1 - 0.0098 16.1 0.1 0.022 15.0 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 EJS43248.1 - 0.033 13.7 0.2 0.097 12.1 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EJS43248.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GSHPx PF00255.19 EJS43249.1 - 4.5e-51 171.0 0.2 5.9e-51 170.6 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EJS43249.1 - 2.6e-05 24.1 0.1 0.00013 21.9 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EJS43249.1 - 0.00012 21.8 0.0 0.00046 19.9 0.0 1.9 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.6 EJS43249.1 - 0.19 12.2 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) GST_N PF02798.20 EJS43250.1 - 2.2e-21 76.0 0.1 3.4e-21 75.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EJS43250.1 - 2.2e-16 59.8 0.0 5e-16 58.7 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EJS43250.1 - 1.6e-08 34.8 0.0 3.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EJS43250.1 - 2.3e-07 31.0 0.0 5.4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EJS43250.1 - 0.00064 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EJS43250.1 - 0.029 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AhpC-TSA PF00578.21 EJS43251.1 - 6.4e-26 90.7 0.0 9.3e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EJS43251.1 - 3.6e-19 68.9 0.0 4.6e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EJS43251.1 - 0.042 14.0 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF1644 PF07800.12 EJS43251.1 - 0.054 13.6 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) AMP-binding PF00501.28 EJS43252.1 - 1.1e-77 261.4 0.0 1.6e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJS43252.1 - 0.0024 18.8 0.1 0.0093 16.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Urm1 PF09138.11 EJS43253.1 - 5.7e-35 119.6 0.5 6.3e-35 119.4 0.5 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EJS43253.1 - 0.00037 21.1 0.0 0.00052 20.6 0.0 1.3 1 0 0 1 1 1 1 ThiS family YchF-GTPase_C PF06071.13 EJS43253.1 - 0.14 12.4 0.1 0.33 11.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF933) Nas2_N PF18265.1 EJS43254.1 - 2e-23 82.1 0.1 3.5e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ PF00595.24 EJS43254.1 - 3.6e-11 43.3 0.1 6.7e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EJS43254.1 - 4.5e-08 32.8 0.0 8.5e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EJS43254.1 - 6.6e-05 23.1 0.1 0.00013 22.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EJS43254.1 - 0.004 17.5 0.0 0.0077 16.6 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Mito_carr PF00153.27 EJS43255.1 - 5.1e-69 228.3 0.5 2.7e-24 84.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Thioredoxin PF00085.20 EJS43256.1 - 3.5e-29 100.8 1.1 8.5e-23 80.3 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin OST3_OST6 PF04756.13 EJS43256.1 - 1.6e-05 24.4 7.7 0.005 16.2 0.1 4.3 4 0 0 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 EJS43256.1 - 8.8e-05 22.5 6.2 0.00084 19.3 0.7 3.4 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EJS43256.1 - 0.002 18.5 4.7 0.21 12.1 0.1 3.8 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_4 PF13462.6 EJS43256.1 - 0.43 10.7 2.1 4.5 7.4 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin FlaC_arch PF05377.11 EJS43257.1 - 0.018 15.4 1.1 0.022 15.1 0.2 1.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HR1 PF02185.16 EJS43257.1 - 0.029 14.5 0.3 0.037 14.1 0.3 1.2 1 0 0 1 1 1 0 Hr1 repeat XhlA PF10779.9 EJS43257.1 - 0.13 12.5 0.7 0.16 12.2 0.7 1.2 1 0 0 1 1 1 0 Haemolysin XhlA Syja_N PF02383.18 EJS43258.1 - 2.9e-45 155.0 0.1 2.9e-45 155.0 0.1 1.6 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 EJS43258.1 - 1.8e-14 53.9 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BTB PF00651.31 EJS43259.1 - 2e-27 95.6 1.4 8.5e-19 67.8 0.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 EJS43259.1 - 3e-07 30.9 0.0 9.8e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJS43259.1 - 2.8e-06 27.8 0.0 1.1e-05 25.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EJS43259.1 - 0.00019 21.8 0.1 0.0065 16.9 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EJS43259.1 - 0.0023 18.2 0.0 0.007 16.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJS43259.1 - 0.0033 17.8 0.0 0.061 13.9 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Spuma_A9PTase PF03539.14 EJS43259.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) ResIII PF04851.15 EJS43260.1 - 1.9e-21 76.8 1.4 5.7e-20 72.0 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EJS43260.1 - 8.9e-20 71.1 3.3 4.7e-18 65.5 0.1 3.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJS43260.1 - 4.3e-17 62.4 0.0 3.7e-16 59.4 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EJS43260.1 - 0.0018 18.5 0.0 0.61 10.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 EJS43260.1 - 0.042 13.3 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein EF-hand_4 PF12763.7 EJS43261.1 - 2.2e-27 95.1 0.0 5.2e-14 52.1 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 EJS43261.1 - 2.4e-19 69.5 241.2 6.9e-08 32.8 16.6 11.2 4 2 7 11 11 11 8 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 EJS43261.1 - 1.5e-06 27.4 0.0 0.0033 16.9 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EJS43261.1 - 1.3e-05 24.8 0.2 1.4 9.0 0.0 4.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 EJS43261.1 - 4e-05 24.0 0.0 0.062 13.8 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair MIS13 PF08202.11 EJS43262.1 - 1.6e-95 319.9 19.7 1.6e-95 319.9 19.7 1.7 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Cut8 PF08559.10 EJS43263.1 - 1.3e-73 247.6 6.4 1.7e-73 247.2 6.4 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein ANAPC4_WD40 PF12894.7 EJS43264.1 - 3.2e-07 30.6 0.6 0.00071 19.8 0.0 4.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EJS43264.1 - 0.00059 19.3 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain PQQ_2 PF13360.6 EJS43264.1 - 0.0018 17.9 0.1 5.3 6.5 0.0 3.1 1 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 EJS43264.1 - 0.12 12.3 0.3 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat Lactonase PF10282.9 EJS43264.1 - 0.17 11.1 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller WD40 PF00400.32 EJS43264.1 - 0.26 12.2 10.2 7.9 7.5 1.2 4.6 5 1 0 5 5 5 0 WD domain, G-beta repeat GATA PF00320.27 EJS43265.1 - 1.5e-14 53.2 2.8 2.4e-14 52.6 2.8 1.3 1 0 0 1 1 1 1 GATA zinc finger VWD PF00094.25 EJS43265.1 - 0.023 14.9 0.0 0.03 14.6 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type D domain bZIP_1 PF00170.21 EJS43266.1 - 3.2e-05 23.9 10.0 3.2e-05 23.9 10.0 2.3 1 1 1 2 2 2 1 bZIP transcription factor MAD PF05557.13 EJS43266.1 - 0.0029 16.0 8.5 0.0039 15.6 8.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF641 PF04859.12 EJS43266.1 - 0.016 15.6 7.4 0.031 14.6 7.4 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Glutaredoxin2_C PF04399.13 EJS43266.1 - 0.026 14.4 1.3 0.047 13.5 1.3 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Bunya_RdRp PF04196.12 EJS43266.1 - 0.083 11.2 3.2 0.11 10.9 3.2 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Ribosomal_L20 PF00453.18 EJS43266.1 - 0.11 12.6 4.7 0.18 11.9 4.7 1.2 1 0 0 1 1 1 0 Ribosomal protein L20 GvpL_GvpF PF06386.11 EJS43266.1 - 0.18 11.7 2.4 0.26 11.2 2.4 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.15 EJS43266.1 - 0.29 11.3 13.0 0.22 11.7 9.5 2.4 2 1 0 2 2 2 0 Basic region leucine zipper Spc7 PF08317.11 EJS43266.1 - 0.67 8.8 11.5 0.94 8.3 11.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 EJS43266.1 - 3 6.4 7.4 4.2 5.9 7.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A BAG PF02179.16 EJS43267.1 - 4.3e-15 55.9 1.7 6.3e-15 55.4 1.7 1.3 1 0 0 1 1 1 1 BAG domain Aa_trans PF01490.18 EJS43268.1 - 2e-135 451.7 14.7 2.3e-135 451.5 14.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aim19 PF10315.9 EJS43269.1 - 5.8e-37 126.5 2.1 7.3e-37 126.2 2.1 1.1 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Glyco_transf_15 PF01793.16 EJS43270.1 - 2.7e-85 286.5 21.0 1.5e-56 192.0 9.5 2.2 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Glyco_hydro_59 PF02057.15 EJS43270.1 - 0.31 10.2 2.1 0.24 10.6 0.4 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 Sds3 PF08598.11 EJS43271.1 - 3e-76 256.2 10.0 3.5e-76 256.0 10.0 1.0 1 0 0 1 1 1 1 Sds3-like Tim44 PF04280.15 EJS43271.1 - 0.029 14.5 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Tim44-like domain zf-CCHC PF00098.23 EJS43272.1 - 2.9e-10 39.7 26.5 2.9e-06 27.1 3.1 5.0 5 1 0 5 5 5 3 Zinc knuckle zf-ribbon_3 PF13248.6 EJS43272.1 - 0.27 10.7 0.1 0.27 10.7 0.1 5.2 4 2 0 4 4 4 0 zinc-ribbon domain zf-CCHC_2 PF13696.6 EJS43272.1 - 1.1 9.2 45.0 0.14 12.0 3.9 5.4 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC_4 PF14392.6 EJS43272.1 - 3 7.7 33.3 2 8.2 0.8 5.2 4 1 1 5 5 5 0 Zinc knuckle DUF1689 PF07954.11 EJS43273.1 - 1.4e-57 194.2 0.2 1.9e-57 193.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) RPN2_C PF18004.1 EJS43274.1 - 1.1e-51 174.9 15.4 1.7e-51 174.3 15.4 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EJS43274.1 - 4.7e-37 124.6 36.4 1.5e-06 28.3 0.0 10.1 11 1 1 12 12 10 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EJS43274.1 - 2.9e-15 56.4 5.8 4.6e-14 52.6 0.2 4.4 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 EJS43274.1 - 1.8e-08 34.7 1.3 0.46 11.0 0.1 5.0 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 EJS43274.1 - 2.2e-07 30.5 2.6 0.71 10.3 0.1 4.6 4 0 0 4 4 4 3 HEAT repeat efThoc1 PF11957.8 EJS43274.1 - 0.00084 18.1 1.5 0.0013 17.5 1.5 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Cnd1 PF12717.7 EJS43274.1 - 0.0081 16.2 4.6 1.8 8.6 0.1 3.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 EJS43274.1 - 0.06 13.6 0.0 0.49 10.7 0.0 2.7 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 EJS43274.1 - 0.12 13.2 5.2 30 5.7 0.0 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat NARP1 PF12569.8 EJS43274.1 - 0.13 11.1 15.2 0.27 10.1 15.2 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4775 PF16001.5 EJS43274.1 - 0.14 11.6 17.0 0.2 11.0 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Vac14_Fab1_bd PF12755.7 EJS43274.1 - 0.38 11.4 1.8 19 5.9 0.0 4.0 4 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region Striatin PF08232.12 EJS43274.1 - 0.5 11.0 11.7 0.97 10.0 11.7 1.4 1 0 0 1 1 1 0 Striatin family FAM176 PF14851.6 EJS43274.1 - 4.6 6.9 7.1 9.6 5.9 7.1 1.4 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.10 EJS43274.1 - 4.7 7.5 18.6 9.5 6.5 18.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MRNIP PF15749.5 EJS43274.1 - 4.8 7.9 10.2 9.8 6.9 10.2 1.4 1 0 0 1 1 1 0 MRN-interacting protein Pox_Ag35 PF03286.14 EJS43274.1 - 8 6.2 15.6 16 5.2 15.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_Rpc4 PF05132.14 EJS43274.1 - 9.5 6.6 9.4 17 5.8 9.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 2-Hacid_dh_C PF02826.19 EJS43275.1 - 4.6e-53 179.2 0.0 6.8e-53 178.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EJS43275.1 - 6.9e-39 132.6 0.0 9.2e-39 132.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EJS43275.1 - 4.7e-06 26.8 0.2 1.2e-05 25.5 0.2 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EJS43275.1 - 0.00017 21.7 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 EJS43275.1 - 0.0022 17.7 0.0 0.0073 16.1 0.0 1.9 1 0 0 1 1 1 1 ACT domain XdhC_C PF13478.6 EJS43275.1 - 0.069 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Acetyltransf_1 PF00583.25 EJS43275.1 - 0.087 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HORMA PF02301.18 EJS43276.1 - 4.2e-56 189.9 0.8 7.9e-56 189.0 0.8 1.5 1 0 0 1 1 1 1 HORMA domain MAM33 PF02330.16 EJS43277.1 - 4.5e-61 206.5 6.2 5.2e-61 206.3 6.2 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Rota_NSP3 PF01665.16 EJS43277.1 - 0.0095 15.1 0.0 0.3 10.2 0.0 2.2 2 0 0 2 2 2 2 Rotavirus non-structural protein NSP3 LCCL PF03815.19 EJS43278.1 - 3.1e-08 33.6 0.1 7.1e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 LCCL domain Ribonuc_red_lgC PF02867.15 EJS43279.1 - 1.6e-180 601.1 0.0 2.1e-180 600.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EJS43279.1 - 2.7e-23 81.8 0.0 8.9e-23 80.1 0.0 2.0 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EJS43279.1 - 6.5e-17 61.9 0.0 2e-16 60.4 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Fis1_TPR_C PF14853.6 EJS43280.1 - 3.5e-24 84.6 0.6 5.5e-24 84.0 0.6 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EJS43280.1 - 3.9e-14 52.0 0.0 6e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat DNA_Packaging_2 PF11123.8 EJS43280.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 DNA packaging protein TPR_19 PF14559.6 EJS43280.1 - 0.13 12.8 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Ran_BP1 PF00638.18 EJS43281.1 - 5.1e-43 146.2 0.6 1.2e-42 145.1 0.6 1.6 1 0 0 1 1 1 1 RanBP1 domain P16-Arc PF04699.14 EJS43282.1 - 1.4e-43 149.0 0.0 1.5e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 EJS43282.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.6 2 0 0 2 2 2 0 Dip2/Utp12 Family U1snRNP70_N PF12220.8 EJS43283.1 - 1.3e-22 80.2 2.4 2.7e-22 79.2 2.4 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EJS43283.1 - 2.3e-15 56.2 0.2 1e-14 54.0 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJS43283.1 - 1.1e-05 25.5 0.1 3.1e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif RGI1 PF10843.8 EJS43284.1 - 3.5e-35 121.4 10.1 6.5e-35 120.5 10.1 1.4 1 1 0 1 1 1 1 Respiratory growth induced protein 1 Vhr1 PF04001.13 EJS43285.1 - 3e-46 155.7 3.6 7.8e-46 154.3 3.6 1.8 1 0 0 1 1 1 1 Transcription factor Vhr1 Codanin-1_C PF15296.6 EJS43285.1 - 0.062 13.4 0.0 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 Codanin-1 C-terminus Plus-3 PF03126.18 EJS43285.1 - 0.2 12.2 1.1 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Plus-3 domain K_channel_TID PF07941.11 EJS43286.1 - 6.2 7.4 13.4 0.039 14.4 3.1 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain HAD_2 PF13419.6 EJS43287.1 - 5.2e-16 59.2 0.0 7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJS43287.1 - 3.6e-12 47.0 0.0 4.7e-08 33.6 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJS43287.1 - 0.0012 18.9 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EJS43287.1 - 0.0037 17.7 0.0 0.0049 17.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rap1-DNA-bind PF09197.10 EJS43287.1 - 0.13 12.9 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 Rap1, DNA-binding ADH_zinc_N PF00107.26 EJS43287.1 - 0.18 11.8 0.3 0.48 10.4 0.1 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Ribonuc_L-PSP PF01042.21 EJS43288.1 - 1.9e-42 144.1 0.9 2.2e-42 143.9 0.9 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cyclin PF08613.11 EJS43289.1 - 3.7e-54 183.5 0.0 6.2e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin Steroid_dh PF02544.16 EJS43290.1 - 2.7e-09 37.2 7.8 5.6e-09 36.1 7.1 1.9 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PhoLip_ATPase_C PF16212.5 EJS43291.1 - 1.1e-49 169.4 18.5 1.1e-49 169.4 18.5 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EJS43291.1 - 9.4e-19 66.9 1.1 2.9e-18 65.3 1.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EJS43291.1 - 4.7e-15 55.6 0.0 1.6e-14 53.9 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EJS43291.1 - 6.3e-11 43.0 0.8 8.8e-06 26.1 0.4 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJS43291.1 - 8.5e-10 38.6 0.0 1.2e-08 35.0 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EJS43291.1 - 0.0011 18.8 2.5 0.0038 17.0 0.0 2.9 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Prot_ATP_ID_OB PF16450.5 EJS43291.1 - 0.12 12.4 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain EXS PF03124.14 EJS43292.1 - 1e-88 297.8 27.1 1.5e-88 297.3 27.1 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EJS43292.1 - 4.4e-38 132.2 0.3 2.4e-24 87.0 0.0 2.4 1 1 1 2 2 2 2 SPX domain RrnaAD PF00398.20 EJS43292.1 - 0.18 10.8 3.0 1.3 8.0 0.3 2.1 1 1 1 2 2 2 0 Ribosomal RNA adenine dimethylase Phage_Mu_Gam PF07352.12 EJS43292.1 - 0.19 11.6 0.5 0.39 10.6 0.5 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein CBM_21 PF03370.13 EJS43293.1 - 2.1e-30 105.2 2.2 4.2e-30 104.2 2.2 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EJS43293.1 - 3.2e-08 34.1 3.9 7.6e-08 32.8 3.9 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DUF1589 PF07628.11 EJS43293.1 - 0.0089 16.2 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1589) ArfGap PF01412.18 EJS43294.1 - 1.4e-37 128.3 0.6 1.4e-37 128.3 0.6 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BCDHK_Adom3 PF10436.9 EJS43295.1 - 3.7e-22 78.9 0.3 6.2e-22 78.2 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EJS43295.1 - 1.1e-14 54.8 0.0 2.1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EJS43295.1 - 0.00047 20.0 0.0 0.00077 19.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BAR_2 PF10455.9 EJS43296.1 - 2.9e-92 308.9 10.4 2.9e-92 308.9 10.4 1.8 1 1 1 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EJS43296.1 - 4.3e-12 46.2 5.3 4.3e-12 46.2 5.3 2.1 2 1 1 3 3 3 1 BAR domain LKAAEAR PF15478.6 EJS43296.1 - 0.0057 16.9 3.0 0.0075 16.5 0.6 2.3 2 0 0 2 2 2 1 Family of unknown function with LKAAEAR motif ApoC-I PF04691.12 EJS43296.1 - 0.079 12.9 2.9 4.9 7.2 0.0 4.2 4 1 0 4 4 4 0 Apolipoprotein C-I (ApoC-1) APG6_N PF17675.1 EJS43296.1 - 0.13 12.8 0.4 0.13 12.8 0.4 3.2 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 EJS43296.1 - 2.8 8.0 6.0 0.56 10.2 0.1 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Apq12 PF12716.7 EJS43297.1 - 8.3e-07 28.9 6.8 1.7e-06 27.8 6.8 1.6 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Metallophos PF00149.28 EJS43298.1 - 3.4e-08 34.3 7.2 2.3e-07 31.5 7.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CreA PF05981.12 EJS43298.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 CreA protein Not3 PF04065.15 EJS43299.1 - 4.4e-80 268.4 28.4 4.4e-80 268.4 28.4 2.9 2 1 1 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EJS43299.1 - 7e-19 68.2 0.3 7e-19 68.2 0.3 3.5 4 0 0 4 4 4 1 NOT2 / NOT3 / NOT5 family PAP1 PF08601.10 EJS43299.1 - 3.9 7.1 35.1 1.7 8.3 14.2 2.5 2 0 0 2 2 2 0 Transcription factor PAP1 Pkinase PF00069.25 EJS43301.1 - 1.1e-57 195.4 5.2 1.2e-50 172.4 0.6 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43301.1 - 1.4e-17 63.8 1.9 2.4e-12 46.7 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EJS43301.1 - 2e-05 24.6 0.0 5.4e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJS43301.1 - 0.011 15.3 0.4 0.04 13.5 0.1 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EJS43301.1 - 0.016 14.0 1.2 0.019 13.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EJS43301.1 - 0.031 13.6 0.3 0.079 12.3 0.4 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family F_actin_cap_B PF01115.17 EJS43302.1 - 6.7e-96 320.5 0.2 7.7e-96 320.3 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit cNMP_binding PF00027.29 EJS43303.1 - 7.4e-43 144.5 0.0 3.6e-21 75.0 0.0 2.5 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RIIa PF02197.17 EJS43303.1 - 5.2e-14 51.6 2.0 1.5e-13 50.2 2.0 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Hydin_ADK PF17213.3 EJS43303.1 - 0.016 15.5 1.2 0.026 14.8 1.2 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Ribosomal_L27 PF01016.19 EJS43303.1 - 0.16 12.0 0.1 0.68 10.0 0.1 2.0 1 1 0 1 1 1 0 Ribosomal L27 protein RINGv PF12906.7 EJS43304.1 - 3.1e-16 59.2 5.1 5.6e-16 58.4 5.1 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EJS43304.1 - 0.13 12.7 5.6 0.38 11.1 5.7 1.8 1 1 0 1 1 1 0 Ring finger domain MMgT PF10270.9 EJS43305.1 - 2.3e-26 92.0 0.1 8.5e-26 90.2 0.1 1.8 1 1 0 1 1 1 1 Membrane magnesium transporter STAG PF08514.11 EJS43306.1 - 5.6e-26 90.7 2.2 5.6e-26 90.7 2.2 3.3 3 0 0 3 3 3 1 STAG domain AMPK1_CBM PF16561.5 EJS43307.1 - 1.1e-06 28.8 1.2 2.2e-06 27.8 1.2 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Zip PF02535.22 EJS43308.1 - 1.2e-59 202.2 16.9 2.3e-44 152.0 5.8 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter LapA_dom PF06305.11 EJS43308.1 - 4.9 7.0 7.4 18 5.2 0.0 3.7 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Tim44 PF04280.15 EJS43309.1 - 5.6e-39 133.6 0.5 1.2e-38 132.5 0.1 1.8 2 0 0 2 2 2 1 Tim44-like domain DUF2228 PF10228.9 EJS43309.1 - 0.008 16.0 0.3 0.017 14.9 0.3 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) Halogen_Hydrol PF10112.9 EJS43309.1 - 0.12 12.4 2.2 4.6 7.2 0.1 3.0 2 1 1 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein RNA_pol_A_bac PF01000.26 EJS43310.1 - 3.9e-31 107.7 0.1 7.9e-31 106.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EJS43310.1 - 1.3e-18 66.1 0.0 1.8e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF4602 PF15375.6 EJS43311.1 - 0.015 15.6 2.0 0.015 15.6 2.0 3.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4602) CDC45 PF02724.14 EJS43311.1 - 0.91 7.7 13.8 1.6 7.0 13.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Complex1_LYR_2 PF13233.6 EJS43312.1 - 5.2e-15 56.0 0.5 1.8e-14 54.2 0.5 1.9 1 1 0 1 1 1 1 Complex1_LYR-like Tam41_Mmp37 PF09139.11 EJS43312.1 - 0.068 12.6 0.3 0.075 12.5 0.3 1.1 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial CLTH PF10607.9 EJS43313.1 - 7e-32 110.4 24.7 2e-31 108.9 9.8 3.3 3 1 0 3 3 3 2 CTLH/CRA C-terminal to LisH motif domain Zn-C2H2_12 PF18112.1 EJS43313.1 - 0.00074 19.9 1.3 0.0025 18.2 1.3 2.0 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain U-box PF04564.15 EJS43313.1 - 0.021 15.0 0.0 0.08 13.1 0.0 2.1 1 0 0 1 1 1 0 U-box domain DUF3922 PF13059.6 EJS43313.1 - 0.024 15.1 0.2 0.12 12.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3992) DUF2431 PF10354.9 EJS43314.1 - 1.2e-50 172.0 0.9 1.2e-50 172.0 0.9 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) Pkinase PF00069.25 EJS43315.1 - 5.2e-37 127.6 0.0 8.5e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43315.1 - 1.5e-29 103.0 0.0 4.4e-29 101.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43315.1 - 0.014 14.7 0.0 0.035 13.4 0.0 1.6 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 EJS43315.1 - 0.25 11.2 0.0 2.4 8.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Iso_dh PF00180.20 EJS43316.1 - 5.8e-115 384.2 0.0 6.8e-115 383.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MRP-S25 PF13741.6 EJS43317.1 - 9.2e-93 310.0 1.1 1.1e-92 309.8 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EJS43317.1 - 0.00018 21.8 1.3 0.048 13.9 1.3 2.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 UTP25 PF06862.12 EJS43318.1 - 8.1e-203 674.4 13.4 9.9e-203 674.2 13.4 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EJS43318.1 - 0.00041 20.2 1.2 0.96 9.2 0.1 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase DUF2538 PF10804.8 EJS43318.1 - 0.075 12.8 0.3 0.6 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2538) ICE2 PF08426.10 EJS43319.1 - 1.7e-162 541.2 22.6 2e-162 541.0 22.6 1.0 1 0 0 1 1 1 1 ICE2 DUF4668 PF15701.5 EJS43320.1 - 5.7e-64 214.8 1.1 6.6e-64 214.6 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4668) Ank_2 PF12796.7 EJS43321.1 - 7.2e-30 103.4 0.0 5.8e-13 49.2 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJS43321.1 - 9.6e-29 99.1 0.1 3.4e-08 33.6 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EJS43321.1 - 3.5e-27 94.4 0.1 1.5e-09 38.1 0.1 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EJS43321.1 - 3e-22 78.0 0.3 2.9e-06 27.5 0.1 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EJS43321.1 - 1.2e-20 71.3 0.0 5.2e-07 29.5 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Imm74 PF15603.6 EJS43321.1 - 0.018 15.2 0.8 0.33 11.2 0.1 2.8 2 0 0 2 2 2 0 Immunity protein 74 DUF249 PF03158.13 EJS43321.1 - 0.04 13.6 0.0 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 Multigene family 530 protein Sec23_trunk PF04811.15 EJS43322.1 - 8.5e-75 251.5 0.0 2.1e-74 250.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EJS43322.1 - 6.7e-20 70.8 0.2 1.8e-19 69.4 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EJS43322.1 - 4.3e-16 58.7 5.5 8.2e-16 57.8 5.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EJS43322.1 - 2.2e-14 54.0 0.2 2.2e-14 54.0 0.2 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 EJS43322.1 - 3.3e-11 42.9 0.0 8.4e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat 6PF2K PF01591.18 EJS43323.1 - 3.1e-86 288.3 0.0 5.6e-86 287.4 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EJS43323.1 - 3e-30 105.4 0.0 1.6e-25 89.9 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EJS43323.1 - 1.1e-06 28.8 0.0 3.2e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EJS43323.1 - 0.00047 20.7 0.0 0.0013 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EJS43323.1 - 0.041 13.8 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 EJS43323.1 - 0.056 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PH PF00169.29 EJS43324.1 - 4.4e-10 40.0 0.2 1e-09 38.8 0.2 1.7 1 0 0 1 1 1 1 PH domain RTT107_BRCT_5 PF16770.5 EJS43324.1 - 0.037 13.9 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain DPM2 PF07297.12 EJS43325.1 - 5.2e-07 29.9 1.2 6.4e-07 29.6 1.2 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EJS43325.1 - 0.4 10.6 2.8 0.51 10.3 2.8 1.2 1 0 0 1 1 1 0 PIG-P LapA_dom PF06305.11 EJS43325.1 - 4.1 7.3 5.5 0.37 10.6 0.7 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CN_hydrolase PF00795.22 EJS43326.1 - 6.8e-07 28.9 0.0 8.4e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_32N PF00251.20 EJS43327.1 - 8e-90 301.5 13.4 1.2e-89 300.9 13.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EJS43327.1 - 6.4e-15 55.5 0.2 1.2e-14 54.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Rio2_N PF09202.11 EJS43328.1 - 0.0042 17.3 0.1 5.4 7.3 0.0 3.0 3 0 0 3 3 3 2 Rio2, N-terminal RWD PF05773.22 EJS43328.1 - 0.051 13.9 0.2 0.075 13.3 0.2 1.3 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.11 EJS43328.1 - 0.098 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Dsh_C PF12316.8 EJS43328.1 - 0.65 10.4 6.9 0.86 10.0 6.9 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Presenilin PF01080.17 EJS43328.1 - 1.1 7.9 7.4 1.2 7.8 7.4 1.1 1 0 0 1 1 1 0 Presenilin Thiolase_N PF00108.23 EJS43329.1 - 5.7e-82 275.0 0.0 7.7e-82 274.5 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EJS43329.1 - 2.3e-50 169.3 0.3 4.1e-50 168.5 0.3 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EJS43329.1 - 0.00037 20.1 0.7 0.00081 19.0 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain FH2 PF02181.23 EJS43330.1 - 1.3e-78 264.7 16.6 1.3e-78 264.7 16.6 2.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EJS43330.1 - 1.6e-06 27.9 1.1 1.6e-06 27.9 1.1 3.8 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Tox-MPTase3 PF15639.6 EJS43330.1 - 0.065 13.1 0.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Metallopeptidase toxin 3 Coa1 PF08695.10 EJS43331.1 - 8.8e-39 131.9 0.0 1.2e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 UCH PF00443.29 EJS43332.1 - 4.1e-64 216.6 3.6 1e-63 215.2 3.6 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJS43332.1 - 6.8e-20 71.9 1.9 5.6e-19 68.9 1.9 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EJS43332.1 - 0.0024 18.3 0.0 0.0067 16.9 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain CpXC PF14353.6 EJS43332.1 - 0.12 12.4 0.7 5.7 7.0 0.0 3.0 3 0 0 3 3 3 0 CpXC protein DAO PF01266.24 EJS43333.1 - 1.4e-57 195.9 0.0 2.3e-57 195.2 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EJS43333.1 - 8.7e-39 132.3 0.0 1.8e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EJS43333.1 - 5e-13 48.9 2.5 2.2e-07 30.3 1.1 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EJS43333.1 - 8.7e-09 35.2 0.3 1.6e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EJS43333.1 - 2.1e-06 27.2 0.2 4.9e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJS43333.1 - 5.1e-06 25.8 1.8 0.0041 16.3 0.7 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 EJS43333.1 - 0.00021 20.1 0.6 0.00037 19.3 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EJS43333.1 - 0.00023 21.3 0.7 0.00081 19.6 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EJS43333.1 - 0.00038 19.8 1.2 0.0058 15.9 1.2 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EJS43333.1 - 0.00072 18.9 0.3 0.0071 15.6 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJS43333.1 - 0.006 15.8 0.4 0.042 13.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family GMC_oxred_N PF00732.19 EJS43333.1 - 0.0093 15.4 0.1 0.034 13.5 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EJS43333.1 - 0.022 13.8 0.8 0.33 10.0 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 EJS43333.1 - 0.15 12.0 1.1 0.46 10.3 0.6 2.0 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DNA_pol_phi PF04931.13 EJS43334.1 - 0.1 10.7 16.0 0.14 10.3 16.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi MIF4G_like_2 PF09090.11 EJS43334.1 - 0.14 11.6 0.3 0.21 11.0 0.3 1.3 1 0 0 1 1 1 0 MIF4G like RRN3 PF05327.11 EJS43334.1 - 0.19 10.2 3.0 0.21 10.1 3.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2722 PF10846.8 EJS43334.1 - 0.33 9.9 4.8 0.43 9.5 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF5523 PF17661.1 EJS43334.1 - 1.1 8.9 8.8 1.5 8.5 8.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Cwf_Cwc_15 PF04889.12 EJS43334.1 - 4.3 7.0 15.7 6.5 6.4 15.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 EJS43334.1 - 5.6 6.8 11.6 60 3.4 12.4 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region CAF1A PF12253.8 EJS43334.1 - 8.1 6.7 14.6 7.6 6.8 13.1 1.8 1 1 0 1 1 1 0 Chromatin assembly factor 1 subunit A PTPA PF03095.15 EJS43335.1 - 3.1e-100 335.5 0.0 3.6e-100 335.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PIN_4 PF13638.6 EJS43337.1 - 2.5e-11 44.0 2.7 5.1e-11 43.0 2.7 1.5 1 0 0 1 1 1 1 PIN domain zf-primase PF09329.11 EJS43338.1 - 1.9e-13 50.0 4.3 4.5e-13 48.8 4.3 1.7 1 0 0 1 1 1 1 Primase zinc finger DUF5088 PF17008.5 EJS43338.1 - 0.016 14.9 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5088) tRNA_anti-codon PF01336.25 EJS43338.1 - 0.021 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain CALCOCO1 PF07888.11 EJS43339.1 - 0.00048 19.1 41.4 0.00048 19.1 41.4 8.4 2 2 5 8 8 8 1 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 EJS43339.1 - 0.0025 17.9 22.5 0.0025 17.9 22.5 15.3 5 3 7 14 14 14 3 TPR/MLP1/MLP2-like protein Apo-CIII PF05778.12 EJS43339.1 - 0.015 14.9 0.5 1.6 8.4 0.1 3.8 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Response_reg PF00072.24 EJS43340.1 - 1.3e-28 99.4 0.2 5.9e-28 97.3 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EJS43340.1 - 5.8e-27 94.4 3.4 5.8e-20 71.9 0.1 3.4 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EJS43340.1 - 1.7e-11 44.0 0.2 5.5e-11 42.3 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EJS43340.1 - 0.0027 18.0 0.9 0.26 11.7 0.1 2.7 2 0 0 2 2 2 1 HAMP domain CTNNB1_binding PF08347.11 EJS43340.1 - 0.52 10.5 4.4 1.5 9.0 4.4 1.7 1 0 0 1 1 1 0 N-terminal CTNNB1 binding ATG27 PF09451.10 EJS43341.1 - 0.011 15.6 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 SWC7 PF17330.2 EJS43341.1 - 0.03 14.4 0.1 0.072 13.2 0.1 1.6 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Pex2_Pex12 PF04757.14 EJS43341.1 - 0.066 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region ArsP_1 PF03773.13 EJS43341.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted permease Pantoate_ligase PF02569.15 EJS43342.1 - 9.8e-92 306.9 0.0 1.1e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ERCC3_RAD25_C PF16203.5 EJS43343.1 - 2e-125 417.0 0.4 3.5e-125 416.2 0.4 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EJS43343.1 - 1e-35 122.7 0.0 2.5e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS43343.1 - 3.8e-16 59.6 0.0 7.6e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EJS43343.1 - 6.1e-12 45.9 0.1 1.4e-11 44.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EJS43343.1 - 4.1e-09 35.6 0.0 4.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EJS43343.1 - 2.4e-05 24.2 0.0 6.5e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.6 EJS43343.1 - 0.034 13.6 0.0 0.099 12.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Nbs1_C PF08599.10 EJS43343.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 Cas_Csm6 PF09659.10 EJS43343.1 - 0.16 10.7 1.4 3 6.5 0.7 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csm6) Cpn60_TCP1 PF00118.24 EJS43344.1 - 3.1e-145 484.6 10.5 3.5e-145 484.4 10.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EJS43344.1 - 0.17 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat SKG6 PF08693.10 EJS43345.1 - 1.6e-17 62.6 2.1 3.9e-17 61.4 2.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain He_PIG PF05345.12 EJS43345.1 - 2.4e-11 43.7 4.5 5.1e-05 23.4 0.0 4.6 4 0 0 4 4 4 2 Putative Ig domain RIFIN PF02009.16 EJS43345.1 - 3.6e-06 27.1 0.7 5.9e-06 26.4 0.7 1.2 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 EJS43345.1 - 1.3e-05 25.1 4.1 3.4e-05 23.8 3.1 2.2 2 0 0 2 2 2 1 TMEM154 protein family Adeno_E3_CR2 PF02439.15 EJS43345.1 - 0.00018 21.2 3.2 0.00034 20.3 3.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Stevor PF17410.2 EJS43345.1 - 0.0002 21.0 0.4 0.00034 20.2 0.4 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF4448 PF14610.6 EJS43345.1 - 0.0019 18.0 0.2 0.0056 16.5 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 EJS43345.1 - 0.0074 16.4 5.9 0.02 15.0 5.9 1.7 1 0 0 1 1 1 1 Podoplanin Amnionless PF14828.6 EJS43345.1 - 0.011 14.6 0.0 0.025 13.4 0.1 1.5 2 0 0 2 2 2 0 Amnionless DUF5305 PF17231.2 EJS43345.1 - 0.025 14.0 1.9 0.057 12.8 1.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Orf78 PF06024.12 EJS43345.1 - 0.042 14.1 1.0 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) DUF4711 PF15829.5 EJS43345.1 - 0.42 10.5 4.9 0.89 9.5 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) Mid2 PF04478.12 EJS43345.1 - 2 8.2 8.9 0.73 9.7 5.4 2.1 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Mucin PF01456.17 EJS43345.1 - 3.2 7.7 26.0 0.33 10.9 20.5 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein HORMA PF02301.18 EJS43346.1 - 9.7e-10 38.4 0.4 2e-09 37.4 0.4 1.4 1 1 0 1 1 1 1 HORMA domain Tropomyosin_1 PF12718.7 EJS43347.1 - 1.6e-47 161.2 41.8 1.9e-47 161.0 41.8 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EJS43347.1 - 2.8e-07 30.2 39.0 0.00052 19.4 16.2 2.1 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.9 EJS43347.1 - 5.9e-05 23.2 29.2 0.014 15.6 13.3 2.1 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein TelA PF05816.11 EJS43347.1 - 0.00034 19.8 3.5 0.00034 19.8 3.5 2.1 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) ATG16 PF08614.11 EJS43347.1 - 0.00042 20.6 35.0 0.033 14.4 15.0 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) ERM PF00769.19 EJS43347.1 - 0.00054 19.9 39.0 0.0046 16.8 19.5 2.0 1 1 1 2 2 2 1 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.8 EJS43347.1 - 0.00059 19.8 46.1 0.0036 17.3 18.7 3.1 2 1 1 3 3 3 2 TATA element modulatory factor 1 DNA binding GAS PF13851.6 EJS43347.1 - 0.00084 18.7 38.7 0.012 15.0 32.7 3.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Uso1_p115_C PF04871.13 EJS43347.1 - 0.00097 19.5 42.1 0.047 14.1 17.4 2.1 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.9 EJS43347.1 - 0.0012 18.1 10.4 0.0012 18.1 10.4 2.0 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 WXG100 PF06013.12 EJS43347.1 - 0.002 18.4 15.9 0.36 11.1 0.1 3.8 2 1 1 3 3 3 1 Proteins of 100 residues with WXG Spc7 PF08317.11 EJS43347.1 - 0.0021 17.0 38.8 0.075 11.9 15.2 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein APG6_N PF17675.1 EJS43347.1 - 0.0022 18.5 47.6 0.47 11.0 22.9 2.1 1 1 1 2 2 2 2 Apg6 coiled-coil region BLOC1_2 PF10046.9 EJS43347.1 - 0.0023 18.2 31.4 0.17 12.2 9.8 3.4 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 EJS43347.1 - 0.0026 17.9 34.3 0.032 14.3 13.1 2.6 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.22 EJS43347.1 - 0.0029 17.8 31.9 0.053 13.7 4.7 2.7 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Taxilin PF09728.9 EJS43347.1 - 0.003 16.8 13.7 0.003 16.8 13.7 2.6 1 1 1 2 2 2 1 Myosin-like coiled-coil protein FlaC_arch PF05377.11 EJS43347.1 - 0.004 17.5 30.7 0.18 12.2 4.6 4.3 1 1 3 4 4 4 3 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 EJS43347.1 - 0.0043 17.1 23.8 0.008 16.2 11.2 2.6 1 1 1 2 2 2 1 Laminin Domain II CENP-F_leu_zip PF10473.9 EJS43347.1 - 0.0055 16.7 42.9 0.08 13.0 10.9 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EJS43347.1 - 0.0063 16.6 18.8 0.036 14.1 5.4 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) EzrA PF06160.12 EJS43347.1 - 0.0094 14.2 33.3 0.18 10.0 18.6 2.1 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA DUF3450 PF11932.8 EJS43347.1 - 0.022 14.1 33.3 0.073 12.4 13.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) MbeD_MobD PF04899.12 EJS43347.1 - 0.026 14.6 2.2 0.026 14.6 2.2 3.1 1 1 1 3 3 3 0 MbeD/MobD like DUF3584 PF12128.8 EJS43347.1 - 0.026 12.1 32.0 0.03 11.8 32.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF724 PF05266.14 EJS43347.1 - 0.028 14.3 31.3 0.33 10.8 12.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 EJS43347.1 - 0.031 14.7 33.2 0.17 12.3 33.2 1.9 1 1 0 1 1 1 0 Fez1 DUF2353 PF09789.9 EJS43347.1 - 0.032 13.6 30.9 0.044 13.1 30.9 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) TPR_MLP1_2 PF07926.12 EJS43347.1 - 0.043 13.9 44.0 7.3 6.7 24.6 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IFT57 PF10498.9 EJS43347.1 - 0.045 12.7 30.3 0.029 13.4 11.1 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 EJS43347.1 - 0.062 13.5 25.9 0.92 9.7 16.0 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family THOC7 PF05615.13 EJS43347.1 - 0.064 13.5 33.3 2.1 8.7 12.6 3.0 1 1 2 3 3 3 0 Tho complex subunit 7 Filament PF00038.21 EJS43347.1 - 0.077 12.6 32.6 0.14 11.7 14.6 2.0 1 1 1 2 2 2 0 Intermediate filament protein Ax_dynein_light PF10211.9 EJS43347.1 - 0.089 12.7 39.0 0.3 11.0 6.1 3.2 1 1 2 3 3 3 0 Axonemal dynein light chain DUF4200 PF13863.6 EJS43347.1 - 0.11 12.8 40.8 1.1 9.6 19.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Lectin_N PF03954.14 EJS43347.1 - 0.12 12.1 17.1 1.2 8.9 5.9 3.0 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF4795 PF16043.5 EJS43347.1 - 0.12 11.9 33.8 0.45 10.1 7.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Uds1 PF15456.6 EJS43347.1 - 0.18 12.0 28.0 0.28 11.4 19.6 2.9 1 1 1 2 2 2 0 Up-regulated During Septation Lebercilin PF15619.6 EJS43347.1 - 0.24 11.0 37.0 2.3 7.8 37.0 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease NPV_P10 PF05531.12 EJS43347.1 - 0.24 11.9 16.9 16 6.0 3.0 4.0 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_S PF02609.16 EJS43347.1 - 0.25 11.4 22.2 0.99 9.5 0.7 4.5 4 0 0 4 4 4 0 Exonuclease VII small subunit MscS_porin PF12795.7 EJS43347.1 - 0.25 10.8 34.5 1.6 8.2 16.6 2.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain OmpH PF03938.14 EJS43347.1 - 0.27 11.5 36.5 0.13 12.6 17.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Sec34 PF04136.15 EJS43347.1 - 0.28 11.1 24.8 0.65 9.9 5.5 2.6 1 1 1 2 2 2 0 Sec34-like family HIP1_clath_bdg PF16515.5 EJS43347.1 - 0.34 11.6 37.3 0.18 12.4 16.4 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 T2SSM PF04612.12 EJS43347.1 - 0.35 10.9 15.1 0.27 11.3 3.4 3.1 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M Vps5 PF09325.10 EJS43347.1 - 0.36 10.3 24.7 0.056 13.0 7.3 2.7 1 1 2 3 3 3 0 Vps5 C terminal like SHE3 PF17078.5 EJS43347.1 - 0.41 10.3 34.2 0.57 9.8 17.0 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DHR10 PF18595.1 EJS43347.1 - 0.44 10.6 38.0 1.5 8.9 16.3 2.7 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain BBP1_C PF15272.6 EJS43347.1 - 0.47 10.3 32.7 0.56 10.0 4.2 3.3 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal HOOK PF05622.12 EJS43347.1 - 0.49 8.5 37.4 0.088 10.9 27.1 2.0 1 1 1 2 2 2 0 HOOK protein DUF4201 PF13870.6 EJS43347.1 - 0.55 9.9 33.5 20 4.9 20.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4107 PF13389.6 EJS43347.1 - 0.55 10.4 7.8 0.62 10.2 6.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) FliD_C PF07195.12 EJS43347.1 - 0.56 9.6 22.8 2.4 7.5 0.4 3.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Spc24 PF08286.11 EJS43347.1 - 0.58 10.4 39.2 3.3 8.0 6.2 4.0 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 MIS13 PF08202.11 EJS43347.1 - 0.69 9.1 31.1 5.8 6.1 11.2 2.2 1 1 1 2 2 2 0 Mis12-Mtw1 protein family CC2-LZ PF16516.5 EJS43347.1 - 0.75 10.2 28.8 0.65 10.4 18.0 2.7 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SLATT_fungal PF18142.1 EJS43347.1 - 0.8 9.7 10.9 0.6 10.1 2.9 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain ZapB PF06005.12 EJS43347.1 - 0.89 10.0 47.1 0.59 10.6 17.5 4.1 2 1 1 3 3 3 0 Cell division protein ZapB HMMR_C PF15908.5 EJS43347.1 - 0.91 9.8 27.3 0.28 11.4 8.4 3.4 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor C-terminal Cortex-I_coil PF09304.10 EJS43347.1 - 0.95 9.7 31.0 1.8 8.8 1.1 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil Muted PF14942.6 EJS43347.1 - 0.96 9.8 35.2 0.18 12.1 16.9 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein AAA_13 PF13166.6 EJS43347.1 - 0.98 8.0 30.2 0.069 11.8 11.5 2.0 1 1 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.8 EJS43347.1 - 1.1 9.5 38.5 1.2 9.3 19.5 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FemAB PF02388.16 EJS43347.1 - 1.1 8.1 26.2 0.39 9.5 8.9 2.0 2 0 0 2 2 2 0 FemAB family Swi5 PF07061.11 EJS43347.1 - 1.1 9.4 33.4 2 8.6 1.5 4.1 1 1 3 4 4 4 0 Swi5 Mod_r PF07200.13 EJS43347.1 - 1.2 9.3 38.1 4.9 7.3 37.9 2.1 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Wtap PF17098.5 EJS43347.1 - 1.3 9.0 30.3 0.21 11.5 21.5 2.4 2 0 0 2 2 2 0 WTAP/Mum2p family DUF16 PF01519.16 EJS43347.1 - 1.6 9.2 27.0 2.9 8.4 9.2 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 FPP PF05911.11 EJS43347.1 - 1.7 6.8 37.9 4.2 5.4 37.9 1.6 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4407 PF14362.6 EJS43347.1 - 1.9 7.8 24.8 3.7 6.8 24.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YtxH PF12732.7 EJS43347.1 - 2 9.0 15.8 1.8e+04 -4.0 15.8 3.2 1 1 0 1 1 0 0 YtxH-like protein DivIC PF04977.15 EJS43347.1 - 2 8.2 38.0 0.1 12.4 8.0 4.1 1 1 3 4 4 4 0 Septum formation initiator FTA4 PF13093.6 EJS43347.1 - 2.4 8.0 24.5 3.4 7.5 16.0 2.4 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Phage_GP20 PF06810.11 EJS43347.1 - 2.7 7.8 34.9 1.3 8.9 13.0 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 Prefoldin_2 PF01920.20 EJS43347.1 - 2.9 7.9 43.6 6.2 6.8 7.5 4.1 1 1 2 4 4 4 0 Prefoldin subunit GCN5L1 PF06320.13 EJS43347.1 - 3.1 8.0 23.8 3.7 7.7 9.8 3.0 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) TMPIT PF07851.13 EJS43347.1 - 3.2 6.9 28.4 1.4 8.1 12.3 2.0 1 1 1 2 2 2 0 TMPIT-like protein CALCOCO1 PF07888.11 EJS43347.1 - 3.4 6.4 34.8 8.5 5.1 34.8 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Jnk-SapK_ap_N PF09744.9 EJS43347.1 - 3.6 7.8 41.9 1.8e+04 -5.8 41.5 2.8 1 1 0 1 1 0 0 JNK_SAPK-associated protein-1 DUF812 PF05667.11 EJS43347.1 - 3.6 6.4 36.7 12 4.7 36.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF745 PF05335.13 EJS43347.1 - 3.7 7.2 22.7 3.5 7.3 6.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF745) MHB PF16525.5 EJS43347.1 - 3.7 7.9 6.1 55 4.1 0.5 3.0 2 1 1 3 3 3 0 Haemophore, haem-binding Tweety PF04906.13 EJS43347.1 - 3.8 6.1 7.7 5.6 5.5 5.9 2.0 1 1 1 2 2 2 0 Tweety bZIP_2 PF07716.15 EJS43347.1 - 3.8 7.7 33.9 0.11 12.6 3.6 4.6 3 1 1 4 4 4 0 Basic region leucine zipper Nup54 PF13874.6 EJS43347.1 - 3.9 7.6 22.2 7.6 6.6 10.1 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 YscO PF07321.12 EJS43347.1 - 3.9 7.4 31.5 3.6 7.5 1.8 3.4 1 1 2 3 3 3 0 Type III secretion protein YscO Noelin-1 PF12308.8 EJS43347.1 - 4 7.5 10.5 1.6 8.8 4.2 2.5 1 1 1 2 2 2 0 Neurogenesis glycoprotein RPW8 PF05659.11 EJS43347.1 - 4.1 7.1 16.6 0.27 10.9 5.6 3.1 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PRKG1_interact PF15898.5 EJS43347.1 - 4.6 8.2 37.5 3.3 8.7 12.9 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain KELK PF15796.5 EJS43347.1 - 4.7 7.7 39.0 0.33 11.4 4.2 4.1 1 1 2 3 3 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fmp27_WPPW PF10359.9 EJS43347.1 - 4.7 5.9 27.7 1.5e+02 1.0 27.7 2.0 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain bZIP_1 PF00170.21 EJS43347.1 - 4.8 7.4 38.6 5.3 7.2 10.7 4.7 1 1 3 4 4 4 0 bZIP transcription factor XhlA PF10779.9 EJS43347.1 - 4.9 7.4 32.3 2.5 8.3 1.5 4.2 1 1 3 5 5 5 0 Haemolysin XhlA MctB PF11382.8 EJS43347.1 - 6.1 6.5 19.1 7.1 6.2 6.2 2.5 1 1 2 3 3 3 0 Copper transport outer membrane protein, MctB UPF0242 PF06785.11 EJS43347.1 - 6.3 6.9 41.5 14 5.7 16.5 2.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus T3SS_basalb_I PF17001.5 EJS43347.1 - 6.9 7.3 13.3 13 6.4 3.2 2.8 1 1 2 3 3 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI KfrA_N PF11740.8 EJS43347.1 - 7 7.4 25.7 10 6.9 3.5 3.6 1 1 3 4 4 4 0 Plasmid replication region DNA-binding N-term Cnn_1N PF07989.11 EJS43347.1 - 7 6.9 38.0 13 6.0 7.6 3.8 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 Phage_GPO PF05929.11 EJS43347.1 - 7.3 6.1 23.0 4.4 6.8 17.0 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4446 PF14584.6 EJS43347.1 - 7.3 6.6 23.6 0.64 10.0 5.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) FapA PF03961.13 EJS43347.1 - 7.4 5.1 32.4 5 5.6 15.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A RmuC PF02646.16 EJS43347.1 - 7.6 5.6 26.2 6.8 5.7 0.7 3.4 1 1 2 3 3 3 0 RmuC family Sec2p PF06428.11 EJS43347.1 - 7.6 6.6 36.7 2 8.4 18.7 3.7 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p PI3K_P85_iSH2 PF16454.5 EJS43347.1 - 8.5 6.0 32.6 1.9 8.0 11.0 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HemX PF04375.14 EJS43347.1 - 9.1 5.5 27.6 24 4.1 8.9 2.3 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase ABC_tran_CTD PF16326.5 EJS43347.1 - 9.6 6.5 42.3 5.2 7.4 5.9 4.2 1 1 3 4 4 4 0 ABC transporter C-terminal domain Peptidase_M1 PF01433.20 EJS43348.1 - 5.2e-62 209.2 3.9 1.3e-61 208.0 3.9 1.7 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EJS43348.1 - 6.6e-40 137.3 0.6 6.6e-40 137.3 0.6 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 EJS43348.1 - 1.4e-36 126.6 0.1 2.2e-36 126.0 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Aminopep PF10023.9 EJS43348.1 - 0.04 13.3 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 Putative aminopeptidase IFT20 PF14931.6 EJS43349.1 - 0.28 11.4 5.4 0.34 11.1 1.2 2.9 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF148 PF02520.17 EJS43349.1 - 0.28 11.3 6.4 0.15 12.2 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF1079 PF06435.11 EJS43349.1 - 2 8.7 8.8 1.3 9.4 0.5 3.1 3 0 0 3 3 3 0 Repeat of unknown function (DUF1079) CSM2 PF16834.5 EJS43350.1 - 1.3e-73 246.9 0.6 1.5e-73 246.7 0.6 1.0 1 0 0 1 1 1 1 Shu complex component Csm2, DNA-binding Fungal_trans PF04082.18 EJS43351.1 - 7.8e-41 139.9 2.3 7.8e-41 139.9 2.3 2.9 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS43351.1 - 7e-11 42.1 12.8 1.2e-10 41.3 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SMC_hinge PF06470.13 EJS43351.1 - 0.04 14.2 0.1 4.4 7.7 0.0 3.0 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain MOR2-PAG1_N PF14222.6 EJS43352.1 - 3.9e-179 597.2 8.1 7.6e-179 596.2 8.1 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EJS43352.1 - 3.9e-89 298.9 4.1 9.8e-89 297.5 0.3 3.7 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EJS43352.1 - 8.7e-22 76.7 18.8 1.6e-10 39.4 0.6 3.9 3 1 0 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.7 EJS43352.1 - 0.039 14.0 2.4 0.2 11.7 0.2 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EJS43353.1 - 2.9e-96 323.2 20.5 2.9e-96 323.2 20.5 3.4 3 1 0 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 EJS43353.1 - 1.8e-83 280.2 15.1 1.5e-79 267.3 5.1 3.6 3 0 0 3 3 3 3 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 EJS43353.1 - 0.00078 19.6 8.6 0.0031 17.7 0.8 3.9 3 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EJS43353.1 - 0.0012 19.3 1.1 1.4 9.5 0.1 4.0 3 1 1 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.6 EJS43353.1 - 0.0028 18.0 0.1 0.039 14.3 0.0 2.9 2 1 0 2 2 2 1 HEAT repeats IBN_N PF03810.19 EJS43353.1 - 0.0038 17.1 1.8 1.1 9.2 0.1 3.9 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.22 EJS43353.1 - 0.004 17.3 0.3 1.2 9.6 0.0 4.5 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EJS43353.1 - 0.014 16.0 4.2 0.48 11.1 0.0 4.5 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region TMCCDC2 PF15844.5 EJS43353.1 - 0.11 12.4 0.0 0.11 12.4 0.0 4.1 4 1 0 4 4 4 0 Transmembrane and coiled-coil domain-containing protein 2 RRT14 PF17075.5 EJS43354.1 - 3e-60 203.7 14.8 3.5e-60 203.5 14.8 1.0 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 FapA PF03961.13 EJS43354.1 - 0.72 8.4 9.4 0.83 8.2 9.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A SpoU_sub_bind PF08032.12 EJS43354.1 - 0.83 10.0 4.6 0.54 10.6 2.6 1.9 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF4065 PF13274.6 EJS43354.1 - 4.7 8.1 8.5 1.5 9.8 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) Transket_pyr PF02779.24 EJS43355.1 - 2.6e-65 219.4 0.0 4.6e-65 218.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EJS43355.1 - 8.9e-58 195.6 0.0 1.3e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EJS43355.1 - 2.5e-49 166.9 0.0 3.9e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EJS43355.1 - 1.2e-19 69.5 2.1 2.9e-19 68.4 2.1 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Cdh1_DBD_1 PF18196.1 EJS43355.1 - 0.036 14.4 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 adh_short PF00106.25 EJS43356.1 - 2.1e-50 170.9 0.0 2.6e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJS43356.1 - 3.8e-29 101.9 0.0 4.6e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJS43356.1 - 2e-07 31.1 0.0 3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EJS43356.1 - 9.9e-06 25.2 0.0 3.4e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EJS43356.1 - 0.00013 21.2 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EJS43356.1 - 0.00038 20.4 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EJS43356.1 - 0.0015 18.0 0.0 1 8.7 0.0 2.6 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 EJS43356.1 - 0.0021 18.3 0.0 0.0041 17.4 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FrhB_FdhB_N PF04422.13 EJS43356.1 - 0.027 14.6 0.1 0.071 13.3 0.0 1.7 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term GDP_Man_Dehyd PF16363.5 EJS43356.1 - 0.066 12.6 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EJS43356.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.17 EJS43356.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rhabdo_M1 PF03342.13 EJS43357.1 - 0.089 12.1 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Myb_DNA-bind_4 PF13837.6 EJS43358.1 - 4e-05 23.9 2.5 4e-05 23.9 2.5 3.3 3 2 0 3 3 3 1 Myb/SANT-like DNA-binding domain Thiolase_N PF00108.23 EJS43358.1 - 0.28 10.5 1.5 0.48 9.7 1.5 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ras PF00071.22 EJS43359.1 - 2.8e-59 199.4 0.0 3.3e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS43359.1 - 5.2e-23 81.5 0.0 7.3e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS43359.1 - 1.7e-09 37.4 0.0 2.5e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EJS43359.1 - 0.00075 18.8 0.0 0.00085 18.6 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 EJS43359.1 - 0.0014 18.0 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EJS43359.1 - 0.0034 16.8 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EJS43359.1 - 0.0046 17.0 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EJS43359.1 - 0.062 13.8 0.0 0.099 13.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EJS43359.1 - 0.13 12.6 0.0 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Raptor_N PF14538.6 EJS43360.1 - 1.7e-66 222.7 0.0 1.7e-66 222.7 0.0 2.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain BBS2_Mid PF14783.6 EJS43360.1 - 3.6e-06 27.0 0.3 0.00096 19.2 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 EJS43360.1 - 4.5e-06 26.5 0.0 0.025 14.8 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat WD40 PF00400.32 EJS43360.1 - 5.1e-06 27.1 2.7 0.26 12.2 0.0 6.0 5 1 1 6 6 6 1 WD domain, G-beta repeat HEAT_2 PF13646.6 EJS43360.1 - 0.011 16.1 0.0 0.1 13.0 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats Mu-like_Pro PF10123.9 EJS43360.1 - 2.7 7.4 9.7 0.39 10.2 0.1 3.1 3 0 0 3 3 3 0 Mu-like prophage I protein Elong_Iki1 PF10483.9 EJS43361.1 - 4.4e-75 252.9 0.2 5.1e-75 252.7 0.2 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DDE_3 PF13358.6 EJS43361.1 - 0.066 13.0 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Pept_tRNA_hydro PF01195.19 EJS43362.1 - 3.4e-34 118.2 0.0 4.1e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase SQS_PSY PF00494.19 EJS43363.1 - 3.1e-39 135.1 0.0 3.8e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase PAS_12 PF18095.1 EJS43363.1 - 0.05 13.2 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain Ctf8 PF09696.10 EJS43364.1 - 6.7e-22 78.4 1.8 1.3e-19 71.0 1.8 2.3 1 1 0 1 1 1 1 Ctf8 DUF5432 PF17497.2 EJS43364.1 - 0.041 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5432) NAC PF01849.18 EJS43365.1 - 4.2e-20 71.5 1.0 2e-19 69.3 0.2 2.1 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.6 EJS43365.1 - 0.00025 20.8 0.5 0.0006 19.6 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain HOIP-UBA PF16678.5 EJS43365.1 - 0.49 10.4 4.8 0.21 11.6 1.9 1.9 2 1 0 2 2 2 0 HOIP UBA domain pair ATP-synt_B PF00430.18 EJS43365.1 - 0.69 10.0 6.6 0.91 9.6 5.7 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) TMF_DNA_bd PF12329.8 EJS43365.1 - 0.69 9.9 0.1 0.69 9.9 0.1 3.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding MDM31_MDM32 PF08118.11 EJS43366.1 - 1.9e-218 726.4 7.4 5.2e-218 725.0 7.4 1.6 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Presenilin PF01080.17 EJS43367.1 - 6.2 5.5 5.2 8.7 5.0 5.2 1.1 1 0 0 1 1 1 0 Presenilin Utp12 PF04003.12 EJS43368.1 - 3.7e-05 24.0 0.4 6.4e-05 23.2 0.4 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family PD40 PF07676.12 EJS43368.1 - 0.00061 19.6 0.5 13 5.9 0.0 3.6 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Chalcone_2 PF16035.5 EJS43369.1 - 2.1e-48 164.9 0.0 2.6e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase like RNase_HII PF01351.18 EJS43369.1 - 0.18 11.6 0.2 1.7 8.4 0.1 2.0 2 0 0 2 2 2 0 Ribonuclease HII VWA_2 PF13519.6 EJS43370.1 - 4.4e-20 72.3 0.7 1.5e-19 70.6 0.0 2.2 2 1 1 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 EJS43370.1 - 1.5e-05 24.9 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 EJS43370.1 - 8.8e-05 22.8 0.2 0.00012 22.3 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_hydro_47 PF01532.20 EJS43372.1 - 5.8e-107 358.4 0.0 7.4e-107 358.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Aminotran_1_2 PF00155.21 EJS43373.1 - 3.7e-15 56.0 0.0 4.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Chs7 PF12271.8 EJS43376.1 - 1.4e-114 382.3 20.5 1.6e-114 382.1 20.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DNA_RNApol_7kD PF03604.13 EJS43378.1 - 5e-16 58.1 2.0 6.6e-16 57.7 2.0 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_SprT PF17283.2 EJS43378.1 - 0.002 18.0 1.1 0.003 17.4 1.1 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain zf_UBZ PF18439.1 EJS43378.1 - 0.0029 17.1 0.6 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger HypA PF01155.19 EJS43378.1 - 0.0051 16.8 0.2 0.0052 16.8 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIS_C PF01096.18 EJS43378.1 - 0.0062 16.4 0.7 2.5 8.0 0.1 2.3 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) zinc-ribbons_6 PF07191.12 EJS43378.1 - 0.012 15.6 0.3 0.015 15.2 0.3 1.2 1 0 0 1 1 1 0 zinc-ribbons UPF0547 PF10571.9 EJS43378.1 - 0.012 15.7 0.4 0.047 13.8 0.4 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Prok-RING_1 PF14446.6 EJS43378.1 - 0.016 15.1 0.4 0.022 14.7 0.4 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DZR PF12773.7 EJS43378.1 - 0.017 15.2 1.0 0.025 14.6 1.0 1.4 1 1 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.22 EJS43378.1 - 0.026 14.4 0.7 0.036 13.9 0.7 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_10 PF10058.9 EJS43378.1 - 0.058 13.1 0.2 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2318 PF10080.9 EJS43378.1 - 0.066 13.3 0.1 0.072 13.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Ribosomal_L40e PF01020.17 EJS43378.1 - 0.1 12.5 3.5 0.13 12.1 3.5 1.2 1 0 0 1 1 1 0 Ribosomal L40e family DUF4428 PF14471.6 EJS43378.1 - 0.11 12.5 1.7 2.5 8.1 1.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) DUF2197 PF09963.9 EJS43378.1 - 0.11 12.8 2.4 6.6 7.1 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF951 PF06107.11 EJS43378.1 - 0.11 12.4 1.1 2.2 8.3 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) TF_Zn_Ribbon PF08271.12 EJS43378.1 - 0.13 11.8 1.6 0.84 9.2 1.9 1.9 1 1 1 2 2 2 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.6 EJS43378.1 - 0.18 12.4 3.0 2.3 8.8 0.6 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 EJS43378.1 - 0.25 11.5 3.2 4.2 7.6 0.4 2.0 1 1 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 EJS43378.1 - 0.33 10.9 3.9 1.8 8.5 3.9 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 EJS43378.1 - 0.53 10.1 2.7 9.7 6.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain dCMP_cyt_deam_1 PF00383.23 EJS43379.1 - 9.5e-28 96.0 2.7 2.7e-27 94.6 2.4 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EJS43379.1 - 5.5e-15 55.3 0.2 9.2e-15 54.6 0.2 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EJS43379.1 - 0.013 15.6 1.3 0.098 12.8 0.9 2.4 2 1 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Holin_BhlA PF10960.8 EJS43379.1 - 0.097 12.6 0.3 0.22 11.5 0.3 1.5 1 0 0 1 1 1 0 BhlA holin family APOBEC_N PF08210.11 EJS43379.1 - 0.2 11.5 4.6 0.34 10.8 2.1 2.4 2 1 0 2 2 2 0 APOBEC-like N-terminal domain AMPK1_CBM PF16561.5 EJS43380.1 - 1.9e-14 53.7 0.1 3.9e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Ribosomal_L6 PF00347.23 EJS43381.1 - 1.1e-26 93.3 2.5 5.1e-16 59.1 0.4 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 DUF4426 PF14467.6 EJS43381.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) S4 PF01479.25 EJS43382.1 - 3.3e-12 45.9 0.0 6.8e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EJS43382.1 - 5.1e-12 46.5 2.2 8e-12 45.9 1.9 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Herpes_LAMP2 PF06126.11 EJS43382.1 - 0.0015 17.3 0.1 0.0017 17.1 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus Latent membrane protein 2 Baculo_gp41 PF04700.12 EJS43382.1 - 0.021 14.6 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region SKG6 PF08693.10 EJS43383.1 - 4.2e-17 61.3 5.9 8e-17 60.4 5.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 EJS43383.1 - 0.00048 19.8 1.9 0.00079 19.1 1.9 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4448 PF14610.6 EJS43383.1 - 0.00098 18.9 0.0 0.00098 18.9 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 EJS43383.1 - 0.0014 18.5 1.1 0.0061 16.5 0.0 2.6 2 0 0 2 2 2 1 TMEM154 protein family Chordopox_A13L PF05961.11 EJS43383.1 - 0.011 16.0 0.2 0.48 10.7 0.0 2.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Orf78 PF06024.12 EJS43383.1 - 0.025 14.8 0.0 0.025 14.8 0.0 2.9 3 0 0 3 3 3 0 Orf78 (ac78) EphA2_TM PF14575.6 EJS43383.1 - 0.11 13.4 0.1 0.88 10.5 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EJS43383.1 - 0.25 11.3 0.5 0.65 10.0 0.5 1.6 1 0 0 1 1 1 0 Syndecan domain HSM3_N PF18795.1 EJS43384.1 - 0.02 14.3 1.8 0.032 13.6 1.8 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain Spo12 PF05032.12 EJS43385.1 - 3.6e-15 55.5 1.0 3.6e-15 55.5 1.0 2.3 2 0 0 2 2 2 1 Spo12 family LMBR1 PF04791.16 EJS43385.1 - 4 6.2 5.5 4.8 6.0 5.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein VASt PF16016.5 EJS43387.1 - 2.1e-12 47.7 3.5 3.5e-12 47.0 2.2 2.1 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain PH PF00169.29 EJS43387.1 - 2.5e-11 44.0 0.5 2.5e-11 44.0 0.5 3.0 3 0 0 3 3 3 1 PH domain BAR_3 PF16746.5 EJS43387.1 - 9.3e-07 28.8 2.2 7.8e-06 25.8 0.1 2.8 2 0 0 2 2 2 1 BAR domain of APPL family FAS_N PF17828.1 EJS43387.1 - 0.022 14.7 1.9 0.044 13.8 0.4 2.3 2 0 0 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta TBCC_N PF16752.5 EJS43387.1 - 0.063 13.7 2.6 0.28 11.7 0.2 3.2 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain E2F_CC-MB PF16421.5 EJS43387.1 - 0.17 12.2 1.7 3.5 8.1 0.1 3.2 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF2614 PF11023.8 EJS43387.1 - 7.2 6.7 6.7 16 5.6 6.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain REC104 PF17378.2 EJS43388.1 - 7.7e-113 374.6 2.8 8.5e-113 374.4 2.8 1.0 1 0 0 1 1 1 1 Meiotic recombination protein REC104 Kelch_5 PF13854.6 EJS43389.1 - 2.4e-32 110.4 5.4 2.6e-06 27.3 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EJS43389.1 - 4.4e-30 103.4 0.5 2.8e-05 24.3 0.0 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 EJS43389.1 - 2e-28 98.1 8.6 5.6e-05 23.1 0.1 6.7 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EJS43389.1 - 3.3e-25 87.5 5.5 0.0002 21.5 0.1 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EJS43389.1 - 5.5e-20 70.7 2.0 0.00057 19.4 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EJS43389.1 - 7.3e-14 51.1 8.6 0.003 17.5 0.0 6.8 6 1 0 6 6 6 4 Kelch motif Coiled PF05710.12 EJS43389.1 - 1.4 9.8 5.3 0.32 11.9 1.0 2.3 2 0 0 2 2 2 0 Coiled coil HALZ PF02183.18 EJS43389.1 - 8.4 6.7 37.9 0.65 10.3 0.7 6.6 6 0 0 6 6 6 0 Homeobox associated leucine zipper ANTH PF07651.16 EJS43390.1 - 1.6e-71 240.6 0.3 1.6e-71 240.6 0.3 1.6 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 EJS43390.1 - 1.3e-07 31.7 0.1 1.3e-07 31.7 0.1 2.1 2 0 0 2 2 2 1 ENTH domain Nrf1_DNA-bind PF10491.9 EJS43390.1 - 1.5 8.5 7.2 0.21 11.2 2.8 1.8 2 0 0 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 R3H-assoc PF13902.6 EJS43390.1 - 1.6 9.1 9.3 0.41 11.0 5.2 2.0 2 0 0 2 2 2 0 R3H-associated N-terminal domain MPC PF03650.13 EJS43391.1 - 8.5e-47 157.9 0.1 1e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 EJS43391.1 - 0.012 15.6 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Dna2 PF08696.11 EJS43392.1 - 7.6e-56 189.1 0.1 7.6e-56 189.1 0.1 2.6 3 0 0 3 3 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 EJS43392.1 - 3.7e-49 167.1 0.2 3.7e-49 167.1 0.2 1.9 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 EJS43392.1 - 3.7e-27 95.8 23.4 4.3e-15 56.2 0.0 4.2 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 EJS43392.1 - 5.4e-14 52.4 0.0 1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJS43392.1 - 2.4e-11 44.2 0.0 5.9e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 EJS43392.1 - 7.3e-06 26.1 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily PIF1 PF05970.14 EJS43392.1 - 0.0004 19.7 0.0 0.0004 19.7 0.0 2.3 3 1 0 3 3 2 1 PIF1-like helicase Cas_Cas4 PF01930.17 EJS43392.1 - 0.00067 19.8 0.0 0.0035 17.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 EJS43392.1 - 0.0011 18.7 3.6 0.44 10.3 0.2 4.3 3 1 1 4 4 4 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EJS43392.1 - 0.0015 18.5 0.7 0.0032 17.3 0.0 2.0 2 0 0 2 2 1 1 Helicase SRP54 PF00448.22 EJS43392.1 - 0.0021 17.7 0.0 0.0054 16.4 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 EJS43392.1 - 0.0049 16.9 0.3 0.0049 16.9 0.3 3.5 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EJS43392.1 - 0.0088 16.4 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 EJS43392.1 - 0.017 14.6 0.0 0.14 11.6 0.0 2.4 1 1 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.15 EJS43392.1 - 0.022 14.7 0.1 0.07 13.0 0.0 2.0 2 0 0 2 2 1 0 NTPase cobW PF02492.19 EJS43392.1 - 0.037 13.6 0.2 0.21 11.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EJS43392.1 - 0.043 13.3 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD_C_2 PF13538.6 EJS43392.1 - 0.058 13.2 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 EJS43392.1 - 0.075 13.0 0.3 0.76 9.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 EJS43392.1 - 0.085 12.9 0.0 0.39 10.8 0.0 2.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 EJS43392.1 - 0.09 13.2 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EJS43392.1 - 0.11 13.0 0.0 0.11 13.0 0.0 2.7 2 1 0 2 2 1 0 AAA domain MobB PF03205.14 EJS43392.1 - 0.12 12.2 0.2 0.29 11.0 0.2 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 EJS43392.1 - 0.26 10.2 1.8 0.33 9.9 0.0 2.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EJS43392.1 - 0.28 11.7 3.3 2.1 8.8 0.0 2.9 2 0 0 2 2 2 0 ABC transporter ANAPC8 PF04049.13 EJS43393.1 - 2e-37 128.4 1.3 3.4e-37 127.6 0.1 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EJS43393.1 - 2.7e-27 93.4 12.5 0.00014 21.5 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 EJS43393.1 - 5.4e-25 85.5 19.8 7.7e-05 22.6 0.1 8.6 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EJS43393.1 - 1.3e-21 74.9 11.0 0.021 14.9 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 EJS43393.1 - 4.2e-15 55.2 0.0 0.00046 20.8 0.0 8.0 6 2 3 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EJS43393.1 - 4.8e-15 55.0 3.8 5.7e-08 32.3 0.0 5.0 3 2 2 5 5 5 2 TPR repeat TPR_12 PF13424.6 EJS43393.1 - 9.9e-12 45.0 10.4 0.00038 20.7 0.0 6.2 2 1 5 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EJS43393.1 - 4.9e-10 39.1 8.4 0.0072 16.6 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EJS43393.1 - 2.1e-09 37.9 0.4 0.0008 20.0 0.0 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EJS43393.1 - 2.2e-09 36.7 0.7 0.2 11.8 0.1 5.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJS43393.1 - 8.2e-09 35.8 1.2 0.11 13.1 0.0 6.5 8 1 1 9 9 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EJS43393.1 - 1.6e-06 28.3 19.4 0.073 13.3 0.0 6.1 5 1 3 8 8 7 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 EJS43393.1 - 5e-06 25.8 0.0 3.1e-05 23.2 0.0 2.1 1 1 2 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.9 EJS43393.1 - 3e-05 23.8 7.2 5.6e-05 22.9 0.1 3.5 4 0 0 4 4 4 1 26S proteasome subunit RPN7 TPR_15 PF13429.6 EJS43393.1 - 0.00012 21.4 1.1 0.27 10.4 0.1 3.7 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EJS43393.1 - 0.00023 21.6 14.1 3.7 8.4 0.1 8.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 EJS43393.1 - 0.0014 18.4 1.6 3.9 7.5 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.17 EJS43393.1 - 0.015 15.8 0.0 0.072 13.5 0.0 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 EJS43393.1 - 0.034 14.3 0.1 0.34 11.1 0.0 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EJS43393.1 - 0.21 11.7 4.9 18 5.5 0.2 4.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain THP2 PF09432.10 EJS43394.1 - 8.8e-54 181.0 2.3 8.8e-54 181.0 2.3 1.6 2 0 0 2 2 2 1 Tho complex subunit THP2 DivIVA PF05103.13 EJS43394.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.6 2 2 0 2 2 2 0 DivIVA protein TFIIE_beta PF02186.15 EJS43394.1 - 0.24 11.7 1.8 0.6 10.4 0.4 2.3 2 0 0 2 2 2 0 TFIIE beta subunit core domain K-box PF01486.17 EJS43394.1 - 1.6 8.9 10.4 7.1 6.9 2.7 3.1 3 0 0 3 3 3 0 K-box region FapA PF03961.13 EJS43394.1 - 2.1 6.9 6.0 8.3 4.9 0.8 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A NMD3 PF04981.13 EJS43395.1 - 5.1e-82 275.0 1.4 5.1e-82 275.0 1.4 1.5 2 0 0 2 2 2 1 NMD3 family DZR PF12773.7 EJS43395.1 - 0.044 13.8 5.5 5 7.2 5.5 2.8 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 EJS43395.1 - 1.6 8.8 6.1 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYVE PF01363.21 EJS43395.1 - 9.4 6.5 7.2 9.9 6.4 3.9 2.5 2 1 0 2 2 2 0 FYVE zinc finger ATG7_N PF16420.5 EJS43396.1 - 7.6e-52 176.8 1.5 3.1e-51 174.8 1.5 1.9 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EJS43396.1 - 2.9e-46 157.8 0.0 4.2e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EJS43396.1 - 0.0069 16.4 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GCP_N_terminal PF17681.1 EJS43397.1 - 1.8e-26 93.5 4.0 8.9e-26 91.2 2.0 2.3 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EJS43397.1 - 1.3e-18 67.5 3.8 2.8e-18 66.4 3.8 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Carot_N PF09150.10 EJS43397.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal DivIVA PF05103.13 EJS43397.1 - 1.5 8.9 6.3 0.69 10.0 0.3 2.9 2 0 0 2 2 2 0 DivIVA protein Enolase_C PF00113.22 EJS43398.1 - 1.3e-149 497.4 0.0 2e-149 496.7 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EJS43398.1 - 1.6e-55 186.9 0.9 2.7e-55 186.1 0.9 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EJS43398.1 - 7.9e-07 28.9 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EJS43398.1 - 0.015 14.5 0.2 0.049 12.8 0.0 1.8 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus FMO-like PF00743.19 EJS43399.1 - 1.1e-40 139.6 1.3 3.5e-33 114.9 0.1 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EJS43399.1 - 1.7e-18 66.9 0.2 2e-15 56.9 0.2 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EJS43399.1 - 9.1e-14 51.4 0.0 3.6e-13 49.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJS43399.1 - 4.3e-10 39.8 0.1 1.4e-07 31.6 0.0 3.7 3 2 1 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EJS43399.1 - 3.4e-08 33.0 1.9 3.1e-06 26.6 0.1 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EJS43399.1 - 1.4e-05 24.5 0.0 0.0037 16.6 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 EJS43399.1 - 0.00037 20.7 0.0 0.00099 19.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EJS43399.1 - 0.0015 17.3 0.3 0.89 8.2 0.0 2.5 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 EJS43399.1 - 0.0031 17.2 0.3 0.61 9.6 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJS43399.1 - 0.12 12.9 0.6 29 5.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 EJS43399.1 - 0.31 10.6 2.5 19 4.8 0.5 3.1 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Fungal_trans PF04082.18 EJS43400.1 - 1.1e-26 93.5 0.2 5.1e-26 91.3 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS43400.1 - 3.6e-07 30.2 12.3 6.5e-07 29.4 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Menin PF05053.13 EJS43400.1 - 0.18 10.1 3.3 0.31 9.4 3.3 1.2 1 0 0 1 1 1 0 Menin Oxidored_FMN PF00724.20 EJS43401.1 - 1.5e-146 488.0 0.0 1.7e-146 487.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ribosomal_L30_N PF08079.12 EJS43401.1 - 0.11 12.8 2.0 0.23 11.7 2.0 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Erv26 PF04148.13 EJS43402.1 - 8.5e-85 283.8 4.5 9.6e-85 283.6 4.5 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 HOASN PF14515.6 EJS43402.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices DUF996 PF06195.13 EJS43402.1 - 0.24 11.7 7.0 0.048 13.9 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF996) RhoGAP PF00620.27 EJS43403.1 - 9.6e-05 22.3 1.0 0.001 18.9 0.1 2.8 2 1 0 2 2 2 1 RhoGAP domain Med9 PF07544.13 EJS43403.1 - 2 8.6 5.9 3.9 7.6 0.1 3.8 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 6PGD PF00393.19 EJS43404.1 - 1.6e-123 411.8 0.0 2e-123 411.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EJS43404.1 - 2.7e-51 173.9 0.0 3.9e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EJS43404.1 - 0.025 15.2 0.1 0.05 14.2 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 EJS43404.1 - 0.072 13.3 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 EJS43404.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RPN1_RPN2_N PF17781.1 EJS43406.1 - 8.5e-114 380.1 0.2 1.9e-113 379.0 0.1 1.6 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EJS43406.1 - 3.2e-28 97.5 0.0 5.9e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EJS43406.1 - 5e-25 86.6 15.9 3.6e-07 30.3 0.2 7.8 8 0 0 8 8 8 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EJS43406.1 - 1.7e-05 25.1 0.9 0.52 10.7 0.0 4.7 4 1 1 5 5 5 2 HEAT repeats Ish1 PF10281.9 EJS43406.1 - 0.048 14.0 0.7 0.12 12.7 0.7 1.7 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF572 PF04502.13 EJS43406.1 - 0.14 11.8 19.0 0.019 14.6 6.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4175 PF13779.6 EJS43406.1 - 0.75 7.6 3.8 7.8 4.3 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DPPIV_N PF00930.21 EJS43407.1 - 1.1e-108 363.2 7.4 1.5e-108 362.8 7.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EJS43407.1 - 1.2e-52 178.4 1.2 2.1e-52 177.7 1.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EJS43407.1 - 6.1e-05 23.7 0.0 0.0028 18.3 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJS43407.1 - 0.048 13.3 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EJS43407.1 - 0.1 12.4 0.1 13 5.5 0.1 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase VCBS PF13517.6 EJS43407.1 - 4.7 7.9 8.0 1.3 9.7 0.2 4.2 3 3 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PhzC-PhzF PF02567.16 EJS43408.1 - 6.4e-80 268.6 0.1 7.2e-80 268.5 0.1 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DAP_epimerase PF01678.19 EJS43408.1 - 0.01 16.0 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 0 Diaminopimelate epimerase ArsD PF06953.11 EJS43408.1 - 0.028 14.7 0.0 0.4 11.0 0.0 2.4 2 1 0 2 2 2 0 Arsenical resistance operon trans-acting repressor ArsD Pkinase PF00069.25 EJS43409.1 - 1.4e-64 218.0 0.2 2.9e-64 217.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43409.1 - 2.1e-31 109.2 0.0 4e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJS43409.1 - 0.00099 18.1 2.0 0.0079 15.2 0.0 2.4 2 1 0 2 2 2 1 Haspin like kinase domain WD40 PF00400.32 EJS43409.1 - 0.054 14.4 0.0 0.32 11.9 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat APH PF01636.23 EJS43409.1 - 0.097 12.6 1.1 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Spt20 PF12090.8 EJS43409.1 - 0.77 9.3 13.8 1.4 8.4 13.8 1.4 1 0 0 1 1 1 0 Spt20 family PIF1 PF05970.14 EJS43410.1 - 1.2e-52 179.3 4.4 5.8e-46 157.3 1.8 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EJS43410.1 - 8.4e-23 81.1 0.0 1.5e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EJS43410.1 - 2.4e-10 40.9 0.1 6.1e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EJS43410.1 - 4e-06 26.5 0.2 1e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EJS43410.1 - 3.9e-05 23.9 1.2 0.00018 21.8 0.3 2.6 3 1 0 3 3 2 1 AAA domain Herpes_Helicase PF02689.14 EJS43410.1 - 4.8e-05 21.5 0.1 0.004 15.2 0.0 2.2 2 0 0 2 2 2 1 Helicase AAA PF00004.29 EJS43410.1 - 0.00032 21.1 0.2 0.00095 19.6 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EJS43410.1 - 0.0009 18.4 0.2 0.0016 17.5 0.2 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SH3_13 PF18335.1 EJS43410.1 - 0.0026 17.5 0.0 0.0097 15.7 0.0 2.0 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain Viral_helicase1 PF01443.18 EJS43410.1 - 0.0035 17.1 0.9 0.43 10.3 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EJS43410.1 - 0.0039 17.1 0.2 0.013 15.4 0.2 1.9 1 1 0 1 1 1 1 Helicase DUF2075 PF09848.9 EJS43410.1 - 0.013 14.8 0.1 0.028 13.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EJS43410.1 - 0.013 14.9 0.1 0.036 13.5 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 EJS43410.1 - 0.017 14.5 0.2 0.042 13.2 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EJS43410.1 - 0.038 14.0 0.3 0.16 12.0 0.3 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 EJS43410.1 - 0.059 12.7 0.2 0.19 11.0 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EJS43410.1 - 0.09 13.3 0.9 0.3 11.6 0.4 2.0 1 1 0 1 1 1 0 ABC transporter UvrD_C_2 PF13538.6 EJS43410.1 - 0.092 12.6 0.7 0.59 10.0 0.7 2.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain RNA_helicase PF00910.22 EJS43410.1 - 0.2 12.0 1.2 1.1 9.7 0.3 2.5 2 1 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 EJS43410.1 - 1.9 8.2 4.6 6.2 6.5 0.1 2.9 3 1 0 3 3 3 0 AAA domain AA_kinase PF00696.28 EJS43411.1 - 2e-36 125.8 0.1 3.3e-36 125.1 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EJS43411.1 - 5.6e-20 71.1 0.0 1.1e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 PUA domain PIH1 PF08190.12 EJS43412.1 - 5.1e-20 71.6 0.3 5.1e-20 71.6 0.3 1.8 2 0 0 2 2 2 1 PIH1 N-terminal domain Pih1_fungal_CS PF18482.1 EJS43412.1 - 3.9e-19 69.0 0.3 8.8e-19 67.8 0.3 1.6 1 0 0 1 1 1 1 Fungal Pih1 CS domain Brr6_like_C_C PF10104.9 EJS43413.1 - 2.2e-42 144.0 4.0 3.2e-42 143.5 4.0 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain RAI16-like PF10257.9 EJS43413.1 - 0.042 12.7 0.0 0.092 11.6 0.0 1.5 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein Aldedh PF00171.22 EJS43414.1 - 1.8e-100 336.7 0.0 2.1e-100 336.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.19 EJS43415.1 - 1.8e-35 122.3 3.3 1.8e-35 122.3 3.3 1.5 2 0 0 2 2 2 1 Ribosome recycling factor Cor1 PF04803.12 EJS43415.1 - 0.00012 22.2 11.1 0.00045 20.4 1.3 2.8 2 1 0 2 2 2 2 Cor1/Xlr/Xmr conserved region Pox_polyA_pol_N PF12630.7 EJS43415.1 - 0.021 15.2 1.3 0.033 14.5 0.4 2.0 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain FGase PF05013.12 EJS43415.1 - 0.17 12.1 0.0 0.6 10.3 0.0 1.8 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase Wx5_PLAF3D7 PF09688.10 EJS43415.1 - 0.18 11.8 3.5 0.15 12.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) DUF5344 PF17279.2 EJS43415.1 - 0.22 12.1 5.0 6.2 7.5 0.4 3.4 2 1 0 3 3 3 0 Family of unknown function (DUF5344) DUF1664 PF07889.12 EJS43415.1 - 0.31 11.1 3.9 7.8 6.6 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ACCA PF03255.14 EJS43415.1 - 0.53 10.2 6.1 2.2 8.2 0.4 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FliD_C PF07195.12 EJS43415.1 - 1.6 8.1 8.8 0.39 10.1 2.2 2.3 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Aldedh PF00171.22 EJS43416.1 - 1.2e-128 429.6 0.0 1.4e-128 429.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_1 PF00667.20 EJS43417.1 - 6.5e-77 258.0 0.0 9.4e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EJS43417.1 - 1.3e-31 109.7 1.0 2.3e-31 109.0 1.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EJS43417.1 - 1.4e-21 77.2 0.0 2.9e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EJS43417.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Spore_IV_A PF09547.10 EJS43417.1 - 0.21 10.5 0.2 0.37 9.7 0.2 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) HAD_2 PF13419.6 EJS43418.1 - 2.1e-15 57.2 0.0 3.5e-15 56.5 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJS43418.1 - 4.7e-08 33.6 0.1 1.9e-06 28.3 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJS43418.1 - 0.015 15.3 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Lipid_DES PF08557.10 EJS43418.1 - 0.18 11.3 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Inositol_P PF00459.25 EJS43420.1 - 1.1e-70 238.3 0.0 1.2e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FSH1 PF03959.13 EJS43421.1 - 8.2e-64 215.1 0.0 9.3e-64 215.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 EJS43421.1 - 0.004 17.1 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 EJS43421.1 - 0.0044 16.8 0.6 1.7 8.4 0.0 2.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase COX5A PF02284.16 EJS43422.1 - 8.2e-40 135.0 1.1 1.1e-39 134.6 1.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Nterm_IS4 PF13006.7 EJS43422.1 - 0.085 13.1 0.1 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal Ribosomal_L1 PF00687.21 EJS43423.1 - 2.1e-34 119.1 9.2 2.1e-34 119.1 9.2 1.6 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Zn_clus PF00172.18 EJS43424.1 - 6.5e-08 32.6 8.8 1.1e-07 31.8 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4680 PF15730.5 EJS43424.1 - 0.033 14.5 0.6 0.08 13.3 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Pro_isomerase PF00160.21 EJS43425.1 - 2.8e-46 157.7 0.6 3.2e-46 157.5 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med6 PF04934.14 EJS43426.1 - 1.4e-49 167.3 1.0 1.9e-49 166.9 1.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.10 EJS43427.1 - 8.5e-25 86.6 0.3 1.2e-24 86.1 0.3 1.3 1 0 0 1 1 1 1 IGR protein motif zf_C2H2_10 PF18414.1 EJS43427.1 - 0.043 13.4 0.1 0.085 12.4 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger RNase_P_p30 PF01876.16 EJS43429.1 - 2.3e-73 246.2 0.0 2.9e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 ApbA PF02558.16 EJS43430.1 - 1.2e-34 119.1 0.0 1.8e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EJS43430.1 - 6.9e-24 84.4 0.0 1.2e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF3862 PF12978.7 EJS43430.1 - 0.14 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3862) HSP70 PF00012.20 EJS43431.1 - 1.3e-75 254.9 3.5 7.5e-75 252.3 1.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EJS43431.1 - 2.4e-11 43.0 0.0 3.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DEAD PF00270.29 EJS43432.1 - 2.9e-49 167.2 0.0 5e-49 166.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS43432.1 - 1.6e-29 102.5 0.1 7.8e-29 100.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS43432.1 - 7.2e-07 29.4 0.0 3.8e-06 27.0 0.0 2.2 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EJS43432.1 - 0.0031 17.3 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EJS43432.1 - 0.0065 16.8 0.0 0.073 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain PIEZO PF15917.5 EJS43432.1 - 0.86 9.0 5.5 1.4 8.4 5.5 1.3 1 0 0 1 1 1 0 Piezo DTHCT PF08070.11 EJS43432.1 - 1.5 9.6 11.7 4.2 8.2 11.7 1.7 1 0 0 1 1 1 0 DTHCT (NUC029) region SpoVIF PF14069.6 EJS43432.1 - 2.2 8.1 8.0 16 5.3 4.0 2.7 2 0 0 2 2 2 0 Stage VI sporulation protein F ATP11 PF06644.11 EJS43432.1 - 8.2 6.1 8.0 12 5.6 8.0 1.2 1 0 0 1 1 1 0 ATP11 protein Brix PF04427.18 EJS43433.1 - 4.1e-50 170.6 3.2 7.7e-50 169.7 3.2 1.4 1 0 0 1 1 1 1 Brix domain DUF2514 PF10721.9 EJS43433.1 - 0.044 13.8 5.6 0.093 12.7 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) MaoC_dehydratas PF01575.19 EJS43434.1 - 0.0011 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain DS PF01916.17 EJS43435.1 - 7e-129 429.2 0.0 8e-129 429.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Met_10 PF02475.16 EJS43436.1 - 1.7e-79 266.2 0.0 2.7e-79 265.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 EJS43436.1 - 0.0023 17.6 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.16 EJS43436.1 - 0.0029 16.8 0.0 0.0055 15.9 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase SUIM_assoc PF16619.5 EJS43436.1 - 0.016 15.3 2.3 0.033 14.2 2.3 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PrmA PF06325.13 EJS43436.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cyclin_N PF00134.23 EJS43437.1 - 3.2e-09 36.6 0.3 4.5e-09 36.1 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EJS43437.1 - 0.0047 17.3 0.6 0.0062 16.9 0.6 1.1 1 0 0 1 1 1 1 Cyclin Nop10p PF04135.12 EJS43438.1 - 1.4e-21 76.3 0.2 1.5e-21 76.1 0.2 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family CN_hydrolase PF00795.22 EJS43439.1 - 1e-44 152.9 0.0 1.3e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EJS43439.1 - 8.8e-22 77.4 0.0 2.2e-21 76.1 0.0 1.6 1 1 0 1 1 1 1 NAD synthase SpoIIE PF07228.12 EJS43440.1 - 1.4e-38 132.8 0.0 2.2e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EJS43440.1 - 1.1e-06 28.5 0.1 0.0025 17.5 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EJS43440.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C ABA_GPCR PF12430.8 EJS43441.1 - 2.3e-60 203.5 3.1 2.3e-60 203.5 3.1 2.1 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EJS43441.1 - 3.3e-16 59.1 0.1 3.3e-16 59.1 0.1 2.3 3 0 0 3 3 3 1 The Golgi pH Regulator (GPHR) Family N-terminal Pkinase PF00069.25 EJS43442.1 - 1e-43 149.7 0.0 2e-41 142.1 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 EJS43442.1 - 3e-42 143.8 0.1 1.3e-41 141.7 0.1 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EJS43442.1 - 6.4e-23 81.3 0.0 9.5e-22 77.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EJS43442.1 - 0.00024 20.5 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ PF01011.21 EJS43442.1 - 0.0033 17.3 0.2 0.11 12.4 0.0 3.3 4 0 0 4 4 4 1 PQQ enzyme repeat Pkinase_fungal PF17667.1 EJS43442.1 - 0.044 12.5 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EJS43442.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQQ_2 PF13360.6 EJS43442.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 PQQ-like domain Sas10_Utp3 PF04000.15 EJS43443.1 - 1.8e-08 34.9 3.3 1.8e-08 34.9 3.3 2.1 2 1 0 2 2 2 1 Sas10/Utp3/C1D family ZapB PF06005.12 EJS43443.1 - 0.034 14.6 1.6 0.35 11.4 0.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB FlgN PF05130.12 EJS43443.1 - 0.1 13.1 2.8 0.29 11.6 1.8 2.2 1 1 0 1 1 1 0 FlgN protein DUF1664 PF07889.12 EJS43443.1 - 0.2 11.7 4.2 0.57 10.2 0.7 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) XRN_M PF17846.1 EJS43443.1 - 0.57 9.1 6.0 0.69 8.8 6.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Complex1_LYR_2 PF13233.6 EJS43443.1 - 0.62 10.8 4.3 6.7 7.5 4.3 2.5 1 1 0 1 1 1 0 Complex1_LYR-like TssO PF17561.2 EJS43443.1 - 1.1 9.3 9.6 2.1 8.5 1.7 2.7 2 1 1 3 3 3 0 Type VI secretion system, TssO DUF3776 PF12618.8 EJS43443.1 - 2.1 8.9 15.3 0.44 11.1 11.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3776) Presenilin PF01080.17 EJS43443.1 - 2.3 6.9 5.0 2.9 6.6 5.0 1.1 1 0 0 1 1 1 0 Presenilin Snapin_Pallidin PF14712.6 EJS43443.1 - 5.4 7.5 8.8 3.6 8.1 1.5 2.8 2 1 1 3 3 3 0 Snapin/Pallidin XhlA PF10779.9 EJS43443.1 - 5.5 7.3 9.9 18 5.6 1.8 3.1 3 0 0 3 3 3 0 Haemolysin XhlA Pkinase PF00069.25 EJS43444.1 - 1.2e-41 142.9 3.9 2.7e-38 131.8 0.7 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43444.1 - 1.8e-19 70.1 1.8 3.9e-19 68.9 0.1 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43444.1 - 0.00016 21.1 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EJS43444.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Inhibitor_I53 PF11714.8 EJS43444.1 - 8 6.7 7.0 26 5.1 3.8 3.1 2 0 0 2 2 2 0 Thrombin inhibitor Madanin SAM35 PF10806.8 EJS43445.1 - 2.1e-43 147.6 0.6 4.3e-43 146.6 0.0 1.8 2 0 0 2 2 2 1 SAM35, subunit of SAM coomplex GST_C_6 PF17171.4 EJS43445.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain STE PF02200.16 EJS43446.1 - 7.2e-59 197.0 2.4 1.1e-58 196.4 2.4 1.3 1 0 0 1 1 1 1 STE like transcription factor Ipi1_N PF12333.8 EJS43447.1 - 2.6e-25 88.9 0.3 7.5e-25 87.5 0.3 1.8 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.6 EJS43447.1 - 0.087 13.2 0.0 11 6.5 0.0 3.0 2 2 0 2 2 2 0 HEAT repeats RRM_1 PF00076.22 EJS43448.1 - 6.5e-43 144.4 0.0 7.5e-17 60.9 0.1 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJS43448.1 - 3.5e-05 23.8 0.0 0.055 13.6 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EJS43448.1 - 0.019 14.9 0.0 0.062 13.3 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EJS43448.1 - 0.085 12.9 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif Brix PF04427.18 EJS43449.1 - 9.3e-25 87.9 0.5 1.5e-24 87.2 0.5 1.3 1 0 0 1 1 1 1 Brix domain Gar1 PF04410.14 EJS43450.1 - 1.6e-39 135.1 0.0 2e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region ING PF12998.7 EJS43451.1 - 1.4e-21 77.0 5.0 1.4e-21 77.0 5.0 2.1 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EJS43451.1 - 4.7e-07 29.6 8.2 1.1e-06 28.4 8.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EJS43451.1 - 0.082 13.2 4.6 0.051 13.8 2.2 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain tRNA-synt_1d PF00750.19 EJS43452.1 - 1.9e-138 461.2 6.4 2.4e-138 460.9 6.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EJS43452.1 - 1.2e-24 86.7 0.1 1.7e-23 83.1 0.0 2.6 2 1 1 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EJS43452.1 - 0.0001 22.8 0.0 0.00026 21.5 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain POT1 PF02765.17 EJS43452.1 - 0.034 14.0 0.1 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 Sugar_tr PF00083.24 EJS43453.1 - 1.5e-172 574.5 36.1 1.8e-172 574.3 36.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS43453.1 - 1e-31 110.2 32.7 1.9e-30 106.0 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec23_trunk PF04811.15 EJS43454.1 - 1.6e-65 221.1 0.0 3.3e-65 220.0 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EJS43454.1 - 9.1e-18 64.0 0.1 2.7e-17 62.5 0.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EJS43454.1 - 2.4e-14 53.8 0.0 5.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EJS43454.1 - 1.9e-10 40.6 2.2 4.1e-10 39.5 2.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EJS43454.1 - 3.8e-09 36.3 0.0 1.7e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat FAT PF02259.23 EJS43455.1 - 1.6e-70 238.0 9.3 3.8e-70 236.8 9.3 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EJS43455.1 - 1.1e-61 208.9 1.7 1.1e-61 208.9 1.7 2.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EJS43455.1 - 0.00019 21.2 0.0 0.00051 19.8 0.0 1.8 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 EJS43455.1 - 0.18 12.0 0.3 32 5.0 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat PXA PF02194.15 EJS43455.1 - 0.43 10.5 5.3 3.4 7.6 0.0 3.9 3 0 0 3 3 3 0 PXA domain Condensin2nSMC PF12422.8 EJS43455.1 - 0.5 10.5 5.0 9.6 6.4 0.2 4.4 2 1 1 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit PGP_phosphatase PF09419.10 EJS43456.1 - 1.1e-71 239.9 0.0 1.2e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EJS43456.1 - 3.2e-06 27.1 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Pkinase PF00069.25 EJS43457.1 - 1.2e-70 237.9 0.0 1.9e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43457.1 - 5.3e-50 170.1 0.0 8.4e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJS43457.1 - 7.7e-06 24.9 3.6 3.6e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EJS43457.1 - 0.00038 19.9 0.1 0.008 15.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Tox-GHH2 PF15635.6 EJS43457.1 - 0.79 10.3 4.2 0.23 12.0 0.2 2.2 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 Haspin_kinase PF12330.8 EJS43457.1 - 3.1 6.6 7.0 0.41 9.5 0.0 2.6 3 0 0 3 3 3 0 Haspin like kinase domain SBE2 PF17076.5 EJS43458.1 - 0 1286.6 38.9 0 1286.3 38.9 1.0 1 0 0 1 1 1 1 SBE2, cell-wall formation Aldo_ket_red PF00248.21 EJS43459.1 - 3.8e-43 147.8 0.0 5.3e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MinC_N PF05209.13 EJS43459.1 - 0.17 11.9 0.0 8.4 6.4 0.0 2.9 1 1 2 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain Pyr_redox_2 PF07992.14 EJS43460.1 - 5.2e-49 167.1 0.1 6e-49 166.9 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJS43460.1 - 1.8e-18 66.9 0.2 2.8e-15 56.6 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJS43460.1 - 1.1e-14 54.4 0.0 5.4e-13 48.9 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EJS43460.1 - 6.3e-05 22.2 1.1 0.62 9.1 0.2 4.1 3 1 1 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EJS43460.1 - 0.00015 22.1 0.0 0.088 13.3 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EJS43460.1 - 0.00031 20.9 0.0 0.04 14.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EJS43460.1 - 0.0011 18.3 0.1 0.0056 16.0 0.1 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EJS43460.1 - 0.0063 15.3 0.5 1.1 7.9 0.1 2.8 2 1 1 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 EJS43460.1 - 0.021 14.0 0.0 1.9 7.5 0.0 3.1 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EJS43460.1 - 0.035 13.7 0.0 2.3 7.7 0.0 2.4 1 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EJS43460.1 - 0.054 12.7 0.0 5.6 6.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 EJS43460.1 - 0.086 11.9 1.9 1.4 7.9 0.1 2.7 2 2 0 3 3 3 0 FAD binding domain Septin PF00735.18 EJS43461.1 - 3.9e-120 400.4 0.1 5.9e-120 399.8 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EJS43461.1 - 1.2e-07 31.8 0.0 2.6e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJS43461.1 - 8.6e-06 25.8 3.5 6.6e-05 22.9 0.1 2.8 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EJS43461.1 - 0.00017 21.2 0.4 0.049 13.2 0.0 2.7 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EJS43461.1 - 0.0016 18.7 0.3 0.0049 17.1 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJS43461.1 - 0.0045 17.4 0.1 0.0098 16.3 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.16 EJS43461.1 - 0.0058 16.0 0.1 0.018 14.3 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 EJS43461.1 - 0.0073 16.5 0.3 0.022 15.0 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EJS43461.1 - 0.01 15.5 0.2 0.029 14.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EJS43461.1 - 0.012 16.0 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EJS43461.1 - 0.017 15.6 0.1 0.057 13.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Pox_A32 PF04665.12 EJS43461.1 - 0.018 14.5 0.1 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein KAP_NTPase PF07693.14 EJS43461.1 - 0.027 13.7 0.0 0.038 13.2 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain IIGP PF05049.13 EJS43461.1 - 0.027 13.5 0.0 0.066 12.3 0.0 1.7 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) NACHT PF05729.12 EJS43461.1 - 0.028 14.3 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 EJS43461.1 - 0.052 13.0 0.1 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EJS43461.1 - 0.055 13.5 4.3 18 5.4 0.0 3.3 2 1 1 3 3 3 0 Dynamin family Sigma54_activat PF00158.26 EJS43461.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Gtr1_RagA PF04670.12 EJS43461.1 - 0.061 12.7 0.1 0.42 9.9 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 EJS43461.1 - 0.081 13.1 0.1 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain PGBA_C PF15437.6 EJS43461.1 - 0.35 11.2 4.9 1.2 9.5 4.9 2.0 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal DUF3970 PF13113.6 EJS43461.1 - 0.92 9.8 3.8 11 6.4 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) VHS PF00790.19 EJS43462.1 - 1.5e-49 167.5 0.1 6.2e-49 165.5 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 EJS43462.1 - 2e-26 92.5 1.4 2e-26 92.5 1.4 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 EJS43462.1 - 1.8e-18 66.6 3.6 6.5e-18 64.8 3.6 2.1 1 0 0 1 1 1 1 GAT domain GGA_N-GAT PF18308.1 EJS43462.1 - 6.3e-06 25.7 2.6 9.2e-06 25.2 0.3 2.4 2 0 0 2 2 2 1 GGA N-GAT domain EMP24_GP25L PF01105.24 EJS43464.1 - 8e-49 166.0 1.5 9.1e-49 165.9 1.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 EJS43464.1 - 0.0088 16.3 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 SdrD B-like domain ThiF PF00899.21 EJS43465.1 - 1e-61 208.4 0.0 1.6e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EJS43465.1 - 5.4e-12 46.2 0.1 1.3e-11 44.9 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 EJS43465.1 - 0.0039 17.2 0.1 0.0081 16.2 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Cys_Met_Meta_PP PF01053.20 EJS43466.1 - 5.7e-66 222.6 0.1 1.7e-65 221.1 0.1 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EJS43466.1 - 0.00025 20.1 0.0 0.00041 19.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EJS43466.1 - 0.0048 16.1 0.0 0.0099 15.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.13 EJS43466.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Peptidase_M18 PF02127.15 EJS43467.1 - 8.6e-186 617.9 0.0 9.8e-186 617.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EJS43467.1 - 1.6e-07 30.6 0.0 0.00012 21.2 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase SH3_1 PF00018.28 EJS43468.1 - 2.3e-25 87.9 0.5 2e-11 43.3 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EJS43468.1 - 4.7e-25 87.2 0.4 5.7e-14 51.7 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 EJS43468.1 - 1.3e-18 67.1 0.1 4.7e-18 65.2 0.1 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 EJS43468.1 - 2.1e-13 49.7 0.1 4.1e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 EJS43468.1 - 0.069 13.4 0.6 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial SH3 domain SH3BP5 PF05276.14 EJS43468.1 - 0.2 11.4 13.1 0.019 14.8 2.5 3.1 3 0 0 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) DUF4407 PF14362.6 EJS43468.1 - 0.25 10.7 8.4 2.6 7.3 2.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) FHA PF00498.26 EJS43469.1 - 6.5e-16 58.4 0.4 1.1e-15 57.7 0.4 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EJS43469.1 - 5.5e-11 42.0 9.8 9.8e-11 41.2 9.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EJS43469.1 - 4.6e-07 30.1 11.1 7.6e-07 29.4 11.1 1.4 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EJS43469.1 - 0.00012 22.3 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Mucin PF01456.17 EJS43469.1 - 0.003 17.6 7.7 0.0055 16.7 7.7 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein zf-ANAPC11 PF12861.7 EJS43469.1 - 0.0062 16.6 4.8 0.012 15.6 4.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EJS43469.1 - 0.0074 16.1 11.1 0.013 15.3 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJS43469.1 - 0.0082 16.1 8.7 0.014 15.4 8.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EJS43469.1 - 0.028 14.3 11.2 0.049 13.5 11.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EJS43469.1 - 0.037 14.3 10.4 0.1 12.9 10.4 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain SSP160 PF06933.11 EJS43469.1 - 0.078 11.2 11.4 0.12 10.5 11.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sec_GG PF07549.14 EJS43469.1 - 0.1 12.1 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-HC5HC2H PF13771.6 EJS43469.1 - 0.13 12.5 4.8 0.26 11.6 4.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_3 PF13920.6 EJS43469.1 - 0.23 11.3 11.1 0.37 10.7 11.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3439 PF11921.8 EJS43469.1 - 0.28 11.2 7.1 0.75 9.8 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FSA_C PF10479.9 EJS43469.1 - 0.6 8.2 4.6 0.94 7.5 4.6 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus zf-RING_UBOX PF13445.6 EJS43469.1 - 1.6 8.8 9.1 3.4 7.8 9.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger TPR_1 PF00515.28 EJS43470.1 - 8.1e-36 120.4 17.1 2.3e-07 30.3 0.5 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 EJS43470.1 - 4.7e-34 113.8 14.4 6.2e-06 25.9 0.1 10.8 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 EJS43470.1 - 4e-28 95.2 11.7 1e-05 25.4 0.0 9.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 EJS43470.1 - 7.3e-23 80.9 16.5 2e-06 28.2 1.2 7.5 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EJS43470.1 - 8.9e-20 70.1 17.7 2.5e-05 23.9 0.2 7.3 5 3 3 8 8 8 5 TPR repeat TPR_17 PF13431.6 EJS43470.1 - 6e-18 63.9 5.2 0.0055 17.0 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EJS43470.1 - 7.8e-16 58.5 0.2 0.0059 17.2 0.0 6.7 5 3 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EJS43470.1 - 8e-16 57.4 2.9 0.21 12.5 0.0 9.7 5 3 6 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EJS43470.1 - 2.7e-14 53.2 9.3 0.0015 18.8 0.0 7.3 7 2 1 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EJS43470.1 - 1.7e-11 44.2 11.2 0.00044 20.4 0.0 5.6 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EJS43470.1 - 4.1e-11 42.9 0.0 0.0026 17.9 0.0 5.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJS43470.1 - 4.5e-08 32.6 6.4 0.41 10.8 0.0 7.8 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 EJS43470.1 - 0.00027 20.7 6.7 0.089 12.7 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 EJS43470.1 - 0.00067 19.4 11.8 0.45 10.2 0.1 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat-like domain Sel1 PF08238.12 EJS43470.1 - 0.00081 20.0 0.3 8.4 7.2 0.0 5.1 6 0 0 6 6 4 1 Sel1 repeat TPR_6 PF13174.6 EJS43470.1 - 0.002 18.6 15.2 21 6.0 0.1 7.5 8 0 0 8 8 6 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EJS43470.1 - 0.012 15.2 0.6 7.1 6.3 0.2 3.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 EJS43470.1 - 0.023 15.0 1.0 2 8.8 0.4 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EJS43470.1 - 0.045 13.7 21.1 0.12 12.4 0.3 5.9 8 0 0 8 8 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EJS43470.1 - 0.38 10.2 2.8 1.1 8.8 0.0 3.3 4 0 0 4 4 4 0 SHNi-TPR Exonuc_VII_S PF02609.16 EJS43470.1 - 0.44 10.7 4.3 2.1 8.5 0.2 3.6 3 0 0 3 3 3 0 Exonuclease VII small subunit ORC6 PF05460.13 EJS43471.1 - 2.7e-103 346.0 4.0 3.2e-103 345.8 4.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) CDC45 PF02724.14 EJS43471.1 - 0.11 10.7 9.4 0.16 10.2 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PGA2 PF07543.12 EJS43471.1 - 9.3 6.2 15.3 27 4.7 15.2 1.8 1 1 0 1 1 1 0 Protein trafficking PGA2 N-SET PF11764.8 EJS43472.1 - 8.7e-48 162.7 2.8 8.7e-48 162.7 2.8 4.2 5 1 0 5 5 5 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 EJS43472.1 - 1e-17 65.0 0.1 1e-17 65.0 0.1 4.9 2 2 0 2 2 2 1 SET domain SET_assoc PF11767.8 EJS43472.1 - 2.6e-17 62.2 0.6 2.6e-17 62.2 0.6 2.2 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated Endonuc-PvuII PF09225.10 EJS43472.1 - 0.015 15.1 0.6 0.033 14.0 0.6 1.5 1 0 0 1 1 1 0 Restriction endonuclease PvuII MutS_V PF00488.21 EJS43473.1 - 2.7e-67 226.5 0.0 4.8e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EJS43473.1 - 1.5e-31 110.1 6.7 2.9e-31 109.2 5.4 2.2 2 2 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EJS43473.1 - 2.3e-29 101.9 0.1 5.2e-29 100.8 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EJS43473.1 - 2.7e-10 40.7 0.4 1.6e-09 38.2 0.0 2.4 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.6 EJS43473.1 - 0.078 12.7 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EJS43473.1 - 0.21 12.1 0.0 0.21 12.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain AD PF09793.9 EJS43474.1 - 9.1e-25 86.6 0.3 1.4e-24 86.0 0.3 1.3 1 0 0 1 1 1 1 Anticodon-binding domain FeS_assembly_P PF01883.19 EJS43475.1 - 1.4e-08 34.8 0.0 2.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein NDT80_PhoG PF05224.12 EJS43476.1 - 4e-69 232.6 0.1 7.8e-69 231.6 0.1 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family PIR PF00399.19 EJS43477.1 - 1.5e-06 27.6 9.7 3.3e-06 26.5 9.7 1.6 1 0 0 1 1 1 1 Yeast PIR protein repeat RRM_1 PF00076.22 EJS43478.1 - 0.037 13.9 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPR3 PF03666.13 EJS43478.1 - 2.2 7.0 5.9 3.5 6.3 5.7 1.4 1 1 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 UPRTase PF14681.6 EJS43479.1 - 1.2e-76 256.8 0.0 1.4e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EJS43479.1 - 0.0086 15.6 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 EJS43479.1 - 0.18 11.8 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.19 EJS43480.1 - 1.7e-109 366.1 0.0 1e-108 363.5 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EJS43480.1 - 0.089 11.6 0.0 3.5 6.4 0.0 2.5 2 1 0 2 2 2 0 MreB/Mbl protein Peptidase_M14 PF00246.24 EJS43481.1 - 1.1e-78 265.0 0.0 1.3e-78 264.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Endosulfine PF04667.17 EJS43482.1 - 4.1e-33 113.3 0.3 5.6e-33 112.9 0.3 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region INSIG PF07281.12 EJS43483.1 - 4.8e-22 78.7 4.4 1e-20 74.3 4.4 2.1 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) Ninjurin PF04923.12 EJS43483.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Ninjurin Thia_YuaJ PF09515.10 EJS43483.1 - 0.17 11.9 6.8 0.56 10.2 2.7 2.3 2 0 0 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) MNHE PF01899.16 EJS43483.1 - 0.39 10.5 4.7 0.2 11.4 2.3 1.7 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit WLM PF08325.10 EJS43484.1 - 2.2e-64 217.0 0.0 2.7e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EJS43484.1 - 0.0045 17.1 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Pkinase PF00069.25 EJS43485.1 - 3.4e-26 92.2 0.0 3.4e-26 92.2 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43485.1 - 5.2e-13 48.9 0.1 1.2e-12 47.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJS43485.1 - 3.9e-09 35.8 0.0 3.9e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase FAM60A PF15396.6 EJS43485.1 - 9.8 6.1 13.8 9.9 6.1 11.9 2.0 2 0 0 2 2 2 0 Protein Family FAM60A RRM_1 PF00076.22 EJS43486.1 - 2.3e-36 123.5 9.3 6.9e-14 51.4 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EJS43486.1 - 0.0037 17.3 0.4 8.6 6.5 0.0 4.1 3 1 0 3 3 3 1 Limkain b1 RRM_5 PF13893.6 EJS43486.1 - 0.0058 16.2 2.1 1.6 8.3 0.1 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EJS43486.1 - 0.008 16.1 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 RL domain RRM_occluded PF16842.5 EJS43486.1 - 0.0083 16.0 0.0 0.09 12.7 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif Radical_SAM PF04055.21 EJS43486.1 - 0.13 12.6 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 Radical SAM superfamily Lyase_1 PF00206.20 EJS43487.1 - 5.3e-97 325.0 0.0 7.3e-97 324.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EJS43487.1 - 1.1e-22 80.6 0.0 2.4e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal tRNA-synt_2 PF00152.20 EJS43488.1 - 3e-90 302.5 0.0 4.3e-90 302.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EJS43488.1 - 1.9e-13 50.2 0.1 4.3e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.11 EJS43488.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain ProRS-C_1 PF09180.11 EJS43489.1 - 7.9e-26 90.1 1.6 1.7e-25 89.0 1.6 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EJS43489.1 - 1.1e-18 67.2 0.1 2.6e-18 66.0 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EJS43489.1 - 5.2e-15 55.9 0.0 1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_M16_C PF05193.21 EJS43490.1 - 4.8e-48 163.6 0.0 1.1e-47 162.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EJS43490.1 - 3.9e-45 153.5 0.0 1.9e-42 144.8 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) DUF3945 PF13101.6 EJS43490.1 - 0.15 11.8 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) ATP-synt_C PF00137.21 EJS43491.1 - 3.4e-23 81.8 40.1 5.4e-17 61.9 12.3 2.8 3 0 0 3 3 3 2 ATP synthase subunit C DUF3671 PF12420.8 EJS43491.1 - 0.89 9.7 7.7 0.48 10.5 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function Form_Nir_trans PF01226.17 EJS43492.1 - 5.8e-61 205.8 22.7 7.5e-61 205.5 22.7 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Pkinase PF00069.25 EJS43493.1 - 1.9e-74 250.3 0.0 3.1e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43493.1 - 9.6e-48 162.7 0.0 1.8e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EJS43493.1 - 6e-23 81.0 0.1 2.9e-22 78.8 0.1 2.3 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EJS43493.1 - 5.1e-05 22.2 0.0 5.1e-05 22.2 0.0 3.3 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EJS43493.1 - 0.00011 21.6 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ANAPC15 PF15243.6 EJS43493.1 - 0.004 17.5 5.9 0.0053 17.1 3.7 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 15 APH PF01636.23 EJS43493.1 - 0.19 11.6 0.0 2.1 8.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S2 PF00318.20 EJS43494.1 - 1.3e-67 227.1 0.0 6.8e-67 224.8 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 TRAM_LAG1_CLN8 PF03798.16 EJS43495.1 - 3.6e-38 131.3 26.1 3.6e-38 131.3 26.1 2.7 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EJS43495.1 - 8.2e-22 76.6 4.0 8.2e-22 76.6 4.0 2.3 2 0 0 2 2 2 1 TRAM1-like protein Oxysterol_BP PF01237.18 EJS43496.1 - 1.2e-84 284.3 0.1 1.1e-82 277.9 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein ThiF PF00899.21 EJS43497.1 - 4.6e-44 150.6 0.0 6.9e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EJS43497.1 - 7.5e-05 22.8 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EJS43497.1 - 0.00022 21.5 0.0 0.00093 19.5 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EJS43497.1 - 0.0017 18.6 0.0 0.0042 17.3 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 EJS43497.1 - 0.0054 17.1 0.0 0.021 15.2 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding ApbA PF02558.16 EJS43497.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PglD_N PF17836.1 EJS43497.1 - 0.033 14.8 0.1 0.42 11.3 0.0 2.6 2 0 0 2 2 2 0 PglD N-terminal domain UDPG_MGDP_dh_N PF03721.14 EJS43497.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NIF PF03031.18 EJS43498.1 - 1.3e-49 168.0 0.0 2e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NGP1NT PF08153.12 EJS43498.1 - 0.29 11.3 1.9 2.5 8.2 0.1 2.6 2 1 1 3 3 3 0 NGP1NT (NUC091) domain G-alpha PF00503.20 EJS43499.1 - 4e-113 378.2 7.2 4.9e-113 377.9 7.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EJS43499.1 - 6e-16 58.4 0.6 1.1e-10 41.2 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EJS43499.1 - 0.0016 17.9 0.5 0.13 11.5 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region PPO1_KFDV PF12143.8 EJS43499.1 - 0.018 15.1 0.1 0.035 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) FtsK_SpoIIIE PF01580.18 EJS43499.1 - 0.02 14.2 0.8 0.25 10.7 0.0 2.5 2 1 1 3 3 3 0 FtsK/SpoIIIE family Drf_GBD PF06371.13 EJS43499.1 - 0.021 14.4 0.5 1.9 8.0 0.1 2.5 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain TniB PF05621.11 EJS43499.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EJS43499.1 - 0.13 12.5 0.5 3.8 7.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain zf-Tim10_DDP PF02953.15 EJS43500.1 - 1.4e-20 72.7 3.4 1.8e-20 72.3 3.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger zf-C2H2_4 PF13894.6 EJS43501.1 - 8.3e-06 26.2 8.7 0.022 15.6 1.2 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EJS43501.1 - 0.00018 21.8 12.9 0.00081 19.7 2.9 3.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EJS43501.1 - 0.17 12.6 0.6 1.5 9.5 0.0 2.8 4 0 0 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 EJS43501.1 - 0.3 11.6 9.6 0.53 10.8 1.0 3.7 3 0 0 3 3 3 0 Zinc-finger double domain PriA_CRR PF18319.1 EJS43501.1 - 0.78 9.8 4.4 1.3 9.1 0.4 3.0 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain p450 PF00067.22 EJS43502.1 - 2.7e-114 382.5 0.0 3.1e-114 382.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol_B_palm PF14792.6 EJS43502.1 - 0.17 12.1 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm Sod_Fe_C PF02777.18 EJS43503.1 - 1.8e-33 114.7 0.9 4e-33 113.6 0.2 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EJS43503.1 - 8.7e-25 87.0 0.6 1.8e-24 86.0 0.6 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.7 EJS43503.1 - 0.1 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DAO PF01266.24 EJS43504.1 - 4.4e-90 302.8 0.0 5.7e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EJS43504.1 - 9e-07 29.0 0.1 2.2e-06 27.8 0.1 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EJS43504.1 - 0.00065 18.7 0.1 0.017 14.0 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 EJS43504.1 - 0.0015 17.8 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJS43504.1 - 0.0023 17.2 0.2 0.005 16.1 0.1 1.5 2 0 0 2 2 2 1 Thi4 family MCRA PF06100.11 EJS43504.1 - 0.003 16.4 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 MCRA family Pyr_redox PF00070.27 EJS43504.1 - 0.0085 16.6 0.0 0.024 15.2 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCM_bind PF09739.9 EJS43504.1 - 0.036 12.5 0.1 0.054 11.9 0.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NAD_binding_9 PF13454.6 EJS43504.1 - 0.059 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EJS43504.1 - 0.064 13.5 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain tRNA-synt_2b PF00587.25 EJS43505.1 - 4.3e-23 82.2 0.0 8.8e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EJS43505.1 - 1.2e-06 28.7 6.2 2.7e-06 27.6 6.2 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.14 EJS43505.1 - 0.00022 21.1 2.3 0.00047 20.0 2.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF724) UPF0242 PF06785.11 EJS43505.1 - 0.00047 20.3 7.9 0.00087 19.4 7.9 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus FmiP_Thoc5 PF09766.9 EJS43505.1 - 0.00081 18.8 5.3 0.0013 18.1 5.3 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Atg14 PF10186.9 EJS43505.1 - 0.0047 16.1 2.4 0.0073 15.4 2.4 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 HOOK PF05622.12 EJS43505.1 - 0.0051 15.0 4.4 0.0066 14.7 4.4 1.1 1 0 0 1 1 1 1 HOOK protein DUF641 PF04859.12 EJS43505.1 - 0.006 16.9 2.7 0.013 15.9 2.7 1.6 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Spc7 PF08317.11 EJS43505.1 - 0.021 13.7 5.5 0.034 13.0 5.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PhaP_Bmeg PF09602.10 EJS43505.1 - 0.024 14.6 2.1 0.053 13.4 2.1 1.5 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CENP-K PF11802.8 EJS43505.1 - 0.034 13.7 4.5 0.058 13.0 4.5 1.3 1 0 0 1 1 1 0 Centromere-associated protein K TMPIT PF07851.13 EJS43505.1 - 0.076 12.3 1.8 0.12 11.6 1.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein ADIP PF11559.8 EJS43505.1 - 0.078 13.1 6.0 0.15 12.1 6.0 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 EJS43505.1 - 0.089 12.8 2.4 0.07 13.2 0.6 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EJS43505.1 - 0.13 12.3 2.3 0.37 10.8 2.5 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EJS43505.1 - 0.18 12.0 5.7 0.39 10.9 5.7 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 EJS43505.1 - 0.23 12.0 3.9 0.6 10.6 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 FliD_C PF07195.12 EJS43505.1 - 0.25 10.7 3.2 0.42 10.0 3.2 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF4407 PF14362.6 EJS43505.1 - 0.29 10.5 2.6 1.8 7.9 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 EJS43505.1 - 0.38 10.6 5.5 13 5.6 3.1 2.8 2 0 0 2 2 2 0 Septum formation initiator Mod_r PF07200.13 EJS43505.1 - 1.1 9.4 8.1 3.2 7.8 8.1 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein AAA_23 PF13476.6 EJS43505.1 - 2.8 8.4 9.6 5.6 7.4 9.6 1.4 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 EJS43506.1 - 2.4e-13 50.3 0.0 3.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJS43506.1 - 1.4e-07 31.5 0.0 2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJS43506.1 - 2.8e-05 24.0 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EJS43506.1 - 0.00026 21.3 0.0 0.00044 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJS43506.1 - 0.017 15.2 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EJS43506.1 - 0.032 13.7 1.0 0.052 13.0 0.9 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 EJS43506.1 - 0.045 14.4 0.0 0.059 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain V-SNARE_C PF12352.8 EJS43508.1 - 9.4e-20 70.7 1.7 9.4e-20 70.7 1.7 2.3 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus U3snoRNP10 PF12397.8 EJS43508.1 - 0.036 14.4 1.8 0.42 11.0 0.1 2.4 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Sec20 PF03908.13 EJS43508.1 - 0.055 13.4 0.5 0.055 13.4 0.5 2.9 2 1 1 3 3 3 0 Sec20 UXS1_N PF11803.8 EJS43508.1 - 0.056 13.8 0.5 2.3 8.7 0.0 3.0 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal Arteri_nucleo PF01481.16 EJS43508.1 - 0.07 13.4 2.3 1.3 9.3 0.0 2.7 3 1 0 3 3 3 0 Arterivirus nucleocapsid protein PMC2NT PF08066.12 EJS43508.1 - 0.3 11.8 8.2 2.6 8.8 0.4 3.0 1 1 1 3 3 3 0 PMC2NT (NUC016) domain Muted PF14942.6 EJS43508.1 - 0.38 11.1 9.1 0.48 10.8 2.9 2.3 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein SYCE1 PF15233.6 EJS43508.1 - 1.2 9.2 8.6 10 6.2 0.4 2.6 1 1 1 3 3 3 0 Synaptonemal complex central element protein 1 Ecm29 PF13001.7 EJS43509.1 - 2.1e-142 475.3 7.8 2.1e-142 475.3 7.8 3.7 4 0 0 4 4 4 1 Proteasome stabiliser HEAT PF02985.22 EJS43509.1 - 4.6e-11 42.0 8.0 0.13 12.6 0.0 8.5 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EJS43509.1 - 2.4e-06 28.0 1.9 0.024 15.2 0.0 6.9 7 2 2 9 9 9 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EJS43509.1 - 2.7e-05 24.6 0.2 0.98 10.0 0.0 5.9 6 0 0 6 6 6 1 HEAT-like repeat FliH PF02108.16 EJS43509.1 - 0.084 12.9 2.3 3.9 7.5 0.0 4.0 3 0 0 3 3 3 0 Flagellar assembly protein FliH zf-C2H2 PF00096.26 EJS43510.1 - 2e-07 31.1 21.8 0.00041 20.6 1.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EJS43510.1 - 0.0047 16.9 1.5 0.01 15.8 1.5 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EJS43510.1 - 0.012 15.9 0.1 0.012 15.9 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EJS43510.1 - 0.013 15.9 2.7 0.013 15.9 2.7 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJS43510.1 - 0.013 16.3 1.3 0.013 16.3 1.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EJS43510.1 - 0.022 15.1 5.3 0.078 13.3 5.3 2.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-met PF12874.7 EJS43510.1 - 0.032 14.6 0.3 0.032 14.6 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 EJS43510.1 - 1.7 9.1 10.2 12 6.5 10.1 2.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger FOXP-CC PF16159.5 EJS43510.1 - 3 8.5 14.2 3.6 8.3 2.3 3.3 2 1 1 3 3 3 0 FOXP coiled-coil domain Ago_PAZ PF18309.1 EJS43511.1 - 0.06 14.0 0.6 0.14 12.8 0.1 1.9 2 0 0 2 2 2 0 Argonaute PAZ domain RRM_1 PF00076.22 EJS43512.1 - 2.2e-27 94.6 1.9 2.2e-14 53.0 0.2 4.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EJS43512.1 - 5.6e-05 23.1 0.2 0.0099 15.9 0.2 2.5 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 EJS43512.1 - 0.0088 15.6 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF386 PF04074.12 EJS43512.1 - 0.0095 15.9 1.5 0.02 14.8 1.5 1.5 1 0 0 1 1 1 1 YhcH/YjgK/YiaL RRM_occluded PF16842.5 EJS43512.1 - 0.074 12.9 0.1 22 5.0 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EJS43512.1 - 0.1 12.6 0.1 7.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif IF2_N PF04760.15 EJS43512.1 - 0.14 12.0 0.4 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region NPR3 PF03666.13 EJS43513.1 - 1.4e-172 574.7 6.8 1.4e-172 574.7 6.8 3.6 3 1 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 TauD PF02668.16 EJS43514.1 - 9.1e-43 147.0 0.0 1.4e-42 146.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EJS43514.1 - 0.0015 19.1 0.0 0.095 13.4 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF971) Adap_comp_sub PF00928.21 EJS43515.1 - 1e-77 261.1 4.7 1e-77 261.1 4.7 1.8 2 0 0 2 2 2 1 Adaptor complexes medium subunit family SR-25 PF10500.9 EJS43515.1 - 0.42 10.2 13.3 0.9 9.1 13.3 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Coilin_N PF15862.5 EJS43515.1 - 0.7 9.7 11.5 0.06 13.2 3.5 2.9 3 0 0 3 3 3 0 Coilin N-terminus Lung_7-TM_R PF06814.13 EJS43516.1 - 1.9e-89 299.8 32.5 2.3e-89 299.6 32.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SCF PF02404.15 EJS43516.1 - 1.4 8.2 5.5 2.7 7.3 0.5 2.9 2 1 1 3 3 3 0 Stem cell factor SSF PF00474.17 EJS43517.1 - 1.2e-17 63.9 29.3 2e-17 63.2 29.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2207 PF09972.9 EJS43517.1 - 0.65 8.7 0.0 0.65 8.7 0.0 4.5 2 1 2 4 4 4 0 Predicted membrane protein (DUF2207) Ribosomal_S10 PF00338.22 EJS43518.1 - 8.4e-25 86.9 1.1 1e-24 86.6 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Phage_Gp19 PF09355.10 EJS43518.1 - 0.024 15.0 0.3 0.027 14.9 0.3 1.2 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 OTU PF02338.19 EJS43519.1 - 7.6e-31 107.2 0.1 7.6e-31 107.2 0.1 1.8 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EJS43519.1 - 0.00023 20.7 8.0 0.00036 20.1 0.0 3.2 1 1 3 4 4 4 2 Peptidase C65 Otubain Pribosyl_synth PF14572.6 EJS43520.1 - 7.3e-42 143.5 2.9 3.8e-36 124.9 2.3 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EJS43520.1 - 5e-38 129.6 0.3 1.7e-37 127.9 0.0 2.0 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EJS43520.1 - 1.2e-16 60.6 1.2 2.5e-16 59.6 0.8 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EJS43520.1 - 0.032 13.7 0.2 0.052 13.0 0.2 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase BRAP2 PF07576.12 EJS43521.1 - 2.2e-32 111.2 3.2 1e-31 109.1 0.6 2.4 2 0 0 2 2 2 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EJS43521.1 - 1e-21 77.0 6.3 1e-21 77.0 6.3 1.8 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EJS43521.1 - 4.1e-09 36.6 11.3 4.1e-09 36.6 11.3 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJS43521.1 - 1.5e-06 28.0 11.1 1.5e-06 28.0 11.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EJS43521.1 - 1.9e-06 27.5 4.8 7.2e-06 25.6 4.8 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EJS43521.1 - 4.5e-06 26.6 7.0 2.7e-05 24.1 7.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EJS43521.1 - 9.9e-06 25.8 8.1 3.3e-05 24.1 8.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EJS43521.1 - 6.1e-05 22.8 10.8 0.00017 21.4 10.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJS43521.1 - 6.1e-05 22.8 8.6 6.1e-05 22.8 8.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJS43521.1 - 8.1e-05 22.5 11.0 8.1e-05 22.5 11.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 EJS43521.1 - 0.0011 18.7 8.0 0.0028 17.4 8.0 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EJS43521.1 - 0.002 18.1 4.6 0.0056 16.7 4.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UBP_var PF17807.1 EJS43521.1 - 0.019 14.7 1.1 0.05 13.4 1.1 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger zinc_ribbon_5 PF13719.6 EJS43521.1 - 0.11 12.3 0.9 0.6 9.9 0.9 2.3 1 0 0 1 1 1 0 zinc-ribbon domain Rad50_zn_hook PF04423.14 EJS43521.1 - 0.12 12.3 1.5 21 5.0 0.2 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 EJS43521.1 - 0.17 11.8 23.4 0.021 14.7 13.5 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Gmx_para_CXXCG PF09535.10 EJS43521.1 - 1.1 8.4 5.1 0.81 8.9 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) bZIP_1 PF00170.21 EJS43522.1 - 3.5e-05 23.8 17.3 3.5e-05 23.8 17.3 2.2 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 EJS43522.1 - 0.17 12.0 16.9 0.41 10.8 15.3 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DUF349 PF03993.12 EJS43522.1 - 0.22 11.9 9.8 0.52 10.7 9.8 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) WDCP PF15390.6 EJS43522.1 - 1.1 7.5 5.9 1.3 7.4 5.9 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Holin_BhlA PF10960.8 EJS43522.1 - 2 8.4 4.7 12 5.9 0.0 2.5 2 0 0 2 2 2 0 BhlA holin family IATP PF04568.12 EJS43522.1 - 3.9 8.0 8.7 0.89 10.0 5.4 1.7 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP SET PF00856.28 EJS43523.1 - 4.7e-05 23.8 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 SET domain DUF507 PF04368.13 EJS43523.1 - 0.0012 18.8 1.7 0.0022 17.9 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF507) RRM_1 PF00076.22 EJS43525.1 - 1.6e-19 69.5 5.8 2.7e-13 49.5 0.1 3.5 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EJS43525.1 - 0.0028 17.5 0.4 1.3 8.8 0.0 3.1 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EJS43525.1 - 0.0048 17.0 0.1 0.92 9.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif HTH_Crp_2 PF13545.6 EJS43525.1 - 0.21 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUP PF00674.18 EJS43526.1 - 1.4e-29 102.2 1.4 2e-29 101.7 1.4 1.2 1 0 0 1 1 1 1 DUP family Epimerase PF01370.21 EJS43527.1 - 2.3e-15 56.7 0.1 8e-15 55.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EJS43527.1 - 1.4e-09 37.4 0.1 1.8e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EJS43527.1 - 1.1e-06 28.1 0.1 1.5e-05 24.3 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EJS43527.1 - 6.7e-06 26.1 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EJS43527.1 - 1e-05 25.1 0.0 4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EJS43527.1 - 1.3e-05 24.8 0.1 2.2e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EJS43527.1 - 0.00019 21.1 0.0 0.00084 19.0 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EJS43527.1 - 0.00059 19.1 0.0 0.0013 17.9 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EJS43527.1 - 0.0012 18.8 0.0 0.0032 17.4 0.0 1.7 2 0 0 2 2 2 1 KR domain PRiA4_ORF3 PF07929.11 EJS43527.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein DUF1507 PF07408.11 EJS43527.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) Pkinase PF00069.25 EJS43528.1 - 7.8e-68 228.7 0.1 2.2e-67 227.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43528.1 - 2e-30 105.9 0.0 3e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43528.1 - 6e-10 38.9 0.0 5.1e-09 35.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_C PF00433.24 EJS43528.1 - 1.9e-09 38.1 2.2 1.9e-09 38.1 2.2 2.7 2 1 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 EJS43528.1 - 9.5e-09 35.5 0.0 0.0022 18.2 0.0 2.7 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 EJS43528.1 - 0.0036 16.3 0.1 0.0036 16.3 0.1 2.8 3 1 0 3 3 3 1 Haspin like kinase domain FTA2 PF13095.6 EJS43528.1 - 0.0066 16.1 0.2 0.39 10.3 0.1 2.5 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Adeno_E3_15_3 PF03307.14 EJS43528.1 - 0.041 13.8 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region SET PF00856.28 EJS43529.1 - 3.3e-15 56.9 6.5 5.6e-14 52.9 6.5 2.7 1 1 0 1 1 1 1 SET domain Myticin-prepro PF10690.9 EJS43529.1 - 6.2 7.1 9.3 9.9 6.5 0.0 3.3 2 1 0 3 3 3 0 Myticin pre-proprotein from the mussel Aminotran_4 PF01063.19 EJS43530.1 - 5.1e-34 118.1 0.0 6.5e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Methyltransf_11 PF08241.12 EJS43531.1 - 5.2e-17 62.3 0.0 9.1e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS43531.1 - 4.9e-16 59.2 0.0 1.1e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJS43531.1 - 3.9e-12 46.8 0.0 1.1e-11 45.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJS43531.1 - 2.4e-09 37.3 0.0 6.2e-09 35.9 0.0 1.6 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJS43531.1 - 2.7e-09 37.0 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EJS43531.1 - 3.3e-06 26.6 0.0 5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EJS43531.1 - 0.002 17.5 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 EJS43531.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 EJS43531.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EJS43531.1 - 0.052 13.5 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EJS43531.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain SKN1 PF03935.15 EJS43532.1 - 3e-254 844.0 6.1 4.1e-254 843.6 6.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) NUC153 PF08159.12 EJS43533.1 - 1.7e-11 43.7 5.2 3.6e-11 42.7 5.2 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EJS43533.1 - 0.21 12.5 1.0 1.2e+02 3.8 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF1279 PF06916.13 EJS43534.1 - 1.2e-20 73.8 0.1 3.4e-20 72.4 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1279) InvH PF04741.12 EJS43534.1 - 0.077 12.9 0.1 0.76 9.7 0.0 2.3 2 1 0 2 2 2 0 InvH outer membrane lipoprotein Ribosomal_L24e PF01246.20 EJS43535.1 - 2.3e-28 98.2 0.2 2.3e-28 98.2 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2838 PF10998.8 EJS43536.1 - 2.7e-42 143.5 16.2 2.7e-42 143.5 16.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) HU-CCDC81_bac_2 PF18175.1 EJS43536.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 PPR_2 PF13041.6 EJS43537.1 - 5.8e-14 52.0 0.8 2.1e-08 34.2 0.0 3.3 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 EJS43537.1 - 2.6e-09 36.7 0.0 1.1e-05 25.3 0.0 3.9 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 EJS43537.1 - 3.5e-06 26.5 0.2 4.5e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EJS43537.1 - 0.00061 19.8 0.5 0.017 15.2 0.1 3.1 1 1 1 2 2 2 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EJS43537.1 - 0.00084 19.0 0.0 0.03 14.0 0.0 2.6 2 0 0 2 2 2 1 PPR repeat TPR_12 PF13424.6 EJS43537.1 - 0.07 13.4 0.0 0.99 9.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Tnp_22_dsRBD PF17490.2 EJS43537.1 - 0.12 12.3 0.1 0.75 9.8 0.0 2.4 2 0 0 2 2 2 0 L1 transposable element dsRBD-like domain Ras PF00071.22 EJS43538.1 - 1.2e-50 171.3 0.0 1.8e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS43538.1 - 1.2e-16 61.1 0.0 2.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS43538.1 - 8.4e-08 31.9 0.1 1.1e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EJS43538.1 - 8.8e-06 25.4 0.1 2e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EJS43538.1 - 0.00047 20.1 0.1 1.6 8.6 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 EJS43538.1 - 0.0037 17.3 0.0 0.0082 16.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4884 PF16225.5 EJS43539.1 - 0.018 15.1 0.1 0.038 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4884) GST_N_2 PF13409.6 EJS43540.1 - 1.4e-16 60.5 0.0 5.5e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EJS43540.1 - 2e-08 34.1 0.0 6.3e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EJS43540.1 - 0.033 14.6 0.0 2.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain PALP PF00291.25 EJS43541.1 - 1.3e-60 205.4 0.0 1.6e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EJS43541.1 - 3.5e-19 69.0 0.1 5.5e-11 42.7 0.1 2.6 2 0 0 2 2 2 2 CBS domain GHMP_kinases_C PF08544.13 EJS43541.1 - 0.014 15.7 0.0 0.67 10.4 0.0 2.8 3 0 0 3 3 3 0 GHMP kinases C terminal CSTF2_hinge PF14327.6 EJS43542.1 - 8.2e-24 83.9 1.7 8.2e-24 83.9 1.7 2.8 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 EJS43542.1 - 4.8e-05 22.9 5.0 4.8e-05 22.9 5.0 3.0 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.22 EJS43542.1 - 0.019 14.8 0.0 0.07 13.0 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MarR PF01047.22 EJS43542.1 - 0.042 13.8 0.1 0.094 12.7 0.1 1.6 1 0 0 1 1 1 0 MarR family PEMT PF04191.13 EJS43543.1 - 8.5e-57 190.1 8.2 1.5e-34 118.6 1.3 4.4 5 1 1 6 6 6 2 Phospholipid methyltransferase SKICH PF17751.1 EJS43543.1 - 0.0081 16.7 1.4 0.18 12.4 1.4 2.6 1 1 0 1 1 1 1 SKICH domain HECW_N PF16562.5 EJS43543.1 - 0.075 12.8 0.1 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 DUF2046 PF09755.9 EJS43544.1 - 0.0019 17.5 0.4 0.0028 16.9 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) CCDC92 PF14916.6 EJS43544.1 - 0.028 14.2 0.6 0.076 12.8 0.4 1.8 2 0 0 2 2 2 0 Coiled-coil domain of unknown function PRKG1_interact PF15898.5 EJS43544.1 - 0.029 15.3 1.6 0.057 14.3 1.6 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain MerR_2 PF13591.6 EJS43544.1 - 0.079 12.8 0.6 0.14 12.0 0.6 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein Sas6_CC PF18594.1 EJS43544.1 - 0.16 11.8 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain MCM3AP_GANP PF16769.5 EJS43544.1 - 0.19 9.9 1.3 0.22 9.8 1.3 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP MIF4G PF02854.19 EJS43546.1 - 2.9e-50 170.9 0.1 4.9e-50 170.1 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EJS43546.1 - 4.3e-25 87.7 0.1 1.2e-24 86.3 0.1 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Fucose_iso_N2 PF07882.12 EJS43546.1 - 0.0078 15.8 0.1 0.028 14.0 0.1 1.9 1 0 0 1 1 1 1 L-fucose isomerase, second N-terminal domain Gtr1_RagA PF04670.12 EJS43547.1 - 3.7e-68 229.3 1.4 4.8e-68 229.0 1.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 EJS43547.1 - 0.00034 20.7 0.0 0.0008 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EJS43547.1 - 0.0096 15.1 0.0 0.027 13.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SRPRB PF09439.10 EJS43547.1 - 0.037 13.5 0.1 0.095 12.1 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EJS43547.1 - 0.066 13.6 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 EJS43547.1 - 0.077 12.4 0.1 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Bot1p PF12298.8 EJS43548.1 - 6.1e-59 199.0 0.1 8.3e-59 198.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Trs65 PF12735.7 EJS43549.1 - 6.6e-50 170.3 1.2 6.6e-50 170.3 1.2 1.6 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 Clathrin_lg_ch PF01086.17 EJS43550.1 - 2.4e-53 181.6 22.9 2.9e-53 181.3 22.9 1.1 1 0 0 1 1 1 1 Clathrin light chain PseudoU_synth_2 PF00849.22 EJS43551.1 - 3.7e-25 88.9 0.0 6.2e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase partial_CstF PF15861.5 EJS43551.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain F-protein PF00469.20 EJS43552.1 - 1.4 8.5 10.7 1.6 8.3 10.7 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef PS_Dcarbxylase PF02666.15 EJS43553.1 - 1.4e-53 181.5 0.0 2.4e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EJS43553.1 - 1.6e-18 66.9 1.6 1.3e-11 44.7 0.1 3.1 3 0 0 3 3 3 2 C2 domain Sif PF06767.11 EJS43553.1 - 0.067 12.2 0.1 1.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Sif protein Yip1 PF04893.17 EJS43554.1 - 1.1e-12 48.0 15.1 1.6e-12 47.5 15.1 1.3 1 0 0 1 1 1 1 Yip1 domain MMR_HSR1_Xtn PF16897.5 EJS43555.1 - 3.8e-36 123.3 0.8 7.3e-36 122.4 0.8 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EJS43555.1 - 1.4e-21 76.7 0.1 3.2e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EJS43555.1 - 1e-18 67.1 0.1 2.8e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 EJS43555.1 - 2.6e-13 49.8 0.0 4.4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EJS43555.1 - 0.00029 20.9 0.4 0.088 12.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 EJS43555.1 - 0.0014 18.0 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 EJS43555.1 - 0.01 15.3 0.7 0.036 13.5 0.1 2.1 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 EJS43555.1 - 0.02 15.1 0.8 0.13 12.5 0.1 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EJS43555.1 - 0.044 13.4 0.6 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Ras family MCM PF00493.23 EJS43555.1 - 0.048 12.8 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain RHH_3 PF12651.7 EJS43555.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain AAA_16 PF13191.6 EJS43555.1 - 0.059 13.8 0.2 0.11 12.9 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain SE PF08491.10 EJS43556.1 - 6.1e-125 415.8 0.0 7.8e-125 415.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EJS43556.1 - 1.8e-14 53.7 0.0 2.4e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJS43556.1 - 1.1e-06 28.5 0.2 0.00014 21.6 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJS43556.1 - 0.0018 18.8 0.4 0.0059 17.1 0.1 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EJS43556.1 - 0.0072 15.4 1.2 0.015 14.4 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EJS43556.1 - 0.0083 16.3 0.1 0.019 15.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EJS43556.1 - 0.014 14.7 0.5 0.055 12.7 0.2 2.0 1 1 2 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EJS43556.1 - 0.025 14.5 0.2 0.041 13.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EJS43556.1 - 0.031 14.3 0.1 0.056 13.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EJS43556.1 - 0.04 13.1 0.4 0.14 11.3 0.1 1.9 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 EJS43556.1 - 0.042 13.2 0.3 0.078 12.3 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GDI PF00996.18 EJS43556.1 - 0.13 10.8 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor UDPG_MGDP_dh_N PF03721.14 EJS43556.1 - 0.16 11.5 0.3 0.46 10.0 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EJS43556.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 EJS43556.1 - 0.18 10.5 0.6 0.73 8.5 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Sacchrp_dh_NADP PF03435.18 EJS43556.1 - 0.34 11.2 1.8 0.42 10.9 0.1 2.0 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain LsmAD PF06741.13 EJS43557.1 - 3e-29 101.4 0.1 3e-29 101.4 0.1 2.2 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 EJS43557.1 - 2.6e-14 53.1 0.1 6.6e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EJS43557.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 Scd6-like Sm domain Ribonuc_red_sm PF00268.21 EJS43558.1 - 1.4e-86 290.4 4.0 1.7e-86 290.2 4.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain zf-Tim10_DDP PF02953.15 EJS43559.1 - 4.5e-19 67.9 0.5 6.6e-19 67.3 0.5 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger zf-UBR PF02207.20 EJS43560.1 - 3.5e-14 52.7 16.3 3.5e-14 52.7 16.3 2.7 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EJS43560.1 - 0.00018 21.2 0.0 0.00053 19.7 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 EJS43560.1 - 0.0019 18.5 4.6 0.0019 18.5 4.6 3.1 3 0 0 3 3 3 1 Ring finger domain tRNA-synt_1b PF00579.25 EJS43561.1 - 7.2e-78 261.9 0.0 9.1e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Mad3_BUB1_I PF08311.12 EJS43562.1 - 1.6e-32 112.1 1.2 4e-32 110.8 1.2 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 EJS43562.1 - 4.9e-27 93.9 0.6 3e-25 88.2 0.0 2.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 EJS43562.1 - 9.1e-15 54.7 0.0 1.7e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43562.1 - 0.0048 16.2 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_16 PF00722.21 EJS43563.1 - 1.2e-45 155.1 2.6 1.2e-45 155.1 2.6 3.5 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 AA_permease PF00324.21 EJS43564.1 - 1.4e-138 462.5 34.9 1.6e-138 462.3 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS43564.1 - 2.5e-36 125.5 36.5 2.9e-36 125.2 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 EJS43564.1 - 0.018 15.5 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 Pet100 Gp_dh_C PF02800.20 EJS43565.1 - 3.4e-72 241.2 0.0 5.9e-72 240.4 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EJS43565.1 - 1.9e-38 130.9 0.0 4e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EJS43565.1 - 0.01 15.9 1.9 0.016 15.3 0.4 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EJS43565.1 - 0.079 12.3 0.1 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Biotin_lipoyl PF00364.22 EJS43566.1 - 3.8e-20 71.5 0.2 7.6e-20 70.5 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EJS43566.1 - 3e-07 30.7 0.0 6.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EJS43566.1 - 0.053 13.4 0.1 0.56 10.1 0.0 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.6 EJS43566.1 - 0.083 13.6 2.9 1.7 9.4 0.0 3.0 2 1 1 3 3 3 0 HlyD family secretion protein RNase_PH PF01138.21 EJS43567.1 - 1.1e-24 87.4 0.0 1.6e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EJS43567.1 - 1.3e-05 25.1 0.4 4.3e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 WD40 PF00400.32 EJS43568.1 - 2.3e-39 132.7 12.9 3.7e-08 33.9 0.0 10.9 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS43568.1 - 1.1e-15 57.6 4.8 0.19 12.0 0.0 8.7 5 4 4 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EJS43568.1 - 0.001 18.5 0.2 0.031 13.6 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain CTP_transf_like PF01467.26 EJS43569.1 - 5.3e-33 114.2 0.0 1.2e-32 113.1 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like Trefoil PF00088.18 EJS43569.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Trefoil (P-type) domain Rhodanese PF00581.20 EJS43570.1 - 4.9e-11 43.1 0.0 5.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain ELK PF03789.13 EJS43570.1 - 4.5 7.5 8.3 15 5.8 0.1 2.8 2 0 0 2 2 2 0 ELK domain FTHFS PF01268.19 EJS43571.1 - 2.6e-251 834.7 0.7 2.6e-251 834.7 0.7 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EJS43571.1 - 5.4e-60 201.3 2.7 6.4e-60 201.1 0.2 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EJS43571.1 - 6.1e-39 132.9 0.1 3e-38 130.7 0.1 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain RNA_helicase PF00910.22 EJS43572.1 - 0.014 15.8 0.0 0.055 13.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.22 EJS43572.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 EJS43572.1 - 0.027 14.5 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EJS43572.1 - 0.028 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 EJS43572.1 - 0.034 14.0 0.0 0.053 13.4 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EJS43572.1 - 0.038 14.4 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EJS43572.1 - 0.042 14.4 0.0 0.074 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EJS43572.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PIF1 PF05970.14 EJS43572.1 - 0.11 11.6 0.1 0.36 10.0 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 EJS43572.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Phage_XkdX PF09693.10 EJS43572.1 - 0.24 11.4 1.5 3.8 7.6 0.2 2.8 2 1 1 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) Mvb12 PF09452.10 EJS43573.1 - 3.4e-38 129.9 1.1 3.9e-38 129.8 1.1 1.0 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 ETF PF01012.21 EJS43574.1 - 4.8e-42 143.9 0.0 6.4e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Hydrolase PF00702.26 EJS43575.1 - 4.1e-16 59.9 0.1 7.9e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJS43575.1 - 2.3e-12 47.7 0.0 4.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EJS43575.1 - 1.2e-07 31.7 4.3 1.2e-06 28.4 1.2 3.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EJS43575.1 - 4.8e-05 22.9 0.3 4.8e-05 22.9 0.3 1.9 2 1 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.6 EJS43575.1 - 7.1e-05 23.0 4.3 0.00062 19.9 0.5 2.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF4790 PF16037.5 EJS43575.1 - 0.063 13.7 0.2 0.83 10.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) Cdh1_DBD_1 PF18196.1 EJS43575.1 - 0.098 13.0 2.2 0.11 12.9 0.6 1.8 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Thioredoxin PF00085.20 EJS43576.1 - 9.6e-32 109.1 0.1 1.1e-31 108.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EJS43576.1 - 3.6e-08 33.8 0.3 3.7e-07 30.5 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EJS43576.1 - 8.8e-07 28.7 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EJS43576.1 - 2.6e-06 27.7 0.0 0.00015 22.0 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EJS43576.1 - 3.1e-06 27.1 0.0 3.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.16 EJS43576.1 - 2.2e-05 24.3 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.10 EJS43576.1 - 8.9e-05 22.2 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 EJS43576.1 - 0.00022 20.7 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EJS43576.1 - 0.0094 16.1 0.2 0.023 14.9 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 EJS43576.1 - 0.018 15.1 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin domain TraF PF13728.6 EJS43576.1 - 0.023 14.5 0.1 0.04 13.7 0.1 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein DUF4290 PF14123.6 EJS43576.1 - 0.044 13.3 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) HyaE PF07449.11 EJS43576.1 - 0.05 13.6 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE MMR_HSR1_C PF08438.10 EJS43577.1 - 3.4e-34 117.8 0.0 5.1e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EJS43577.1 - 2.3e-20 72.8 0.0 4.4e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJS43577.1 - 1.2e-06 28.2 0.3 1.3e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EJS43577.1 - 0.0066 16.0 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EJS43577.1 - 0.011 15.8 0.1 0.047 13.7 0.1 2.1 2 0 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 EJS43577.1 - 0.063 13.2 0.8 1.7 8.5 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase KTI12 PF08433.10 EJS43577.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.18 EJS43577.1 - 0.14 11.5 0.3 0.54 9.6 0.2 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 EJS43577.1 - 0.18 11.6 0.4 12 5.6 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein zf-ZPR1 PF03367.13 EJS43578.1 - 7.3e-118 389.9 7.1 8.8e-59 197.9 1.8 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 EJS43578.1 - 0.00028 20.9 5.0 0.22 11.6 0.5 2.5 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 EJS43578.1 - 4.4 7.4 10.3 0.21 11.6 1.8 2.6 2 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_2 PF13240.6 EJS43578.1 - 7.5 6.4 17.4 4.3 7.2 0.2 4.2 4 0 0 4 4 4 0 zinc-ribbon domain Gpi1 PF05024.15 EJS43579.1 - 1.2e-59 201.6 16.3 1.2e-59 201.6 16.3 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) CRM1_C PF08767.11 EJS43580.1 - 9.9e-131 435.7 7.1 9.9e-131 435.7 7.1 3.1 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 EJS43580.1 - 8.3e-38 129.8 7.1 8.3e-38 129.8 7.1 3.8 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EJS43580.1 - 2.4e-31 107.2 3.5 6.6e-31 105.8 3.5 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EJS43580.1 - 1.9e-27 95.1 0.5 6.2e-26 90.3 0.3 3.6 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EJS43580.1 - 1.5e-16 59.6 0.6 1.5e-16 59.6 0.6 3.1 3 0 0 3 3 3 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EJS43580.1 - 7e-16 57.9 1.5 2.9e-15 55.9 0.1 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF507 PF04368.13 EJS43580.1 - 0.41 10.6 5.2 2.7 7.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF507) V-ATPase_H_C PF11698.8 EJS43580.1 - 1 9.5 8.0 0.65 10.1 0.1 3.9 5 0 0 5 5 5 0 V-ATPase subunit H Ribosomal_L3 PF00297.22 EJS43581.1 - 1.9e-19 69.9 1.8 1.7e-16 60.2 1.8 2.2 1 1 0 1 1 1 1 Ribosomal protein L3 Pyr_redox PF00070.27 EJS43581.1 - 0.12 12.9 0.1 0.32 11.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ge1_WD40 PF16529.5 EJS43583.1 - 0.006 15.6 2.0 0.011 14.7 0.1 2.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EJS43583.1 - 0.013 15.8 0.1 0.62 10.4 0.0 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EJS43583.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.4 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 EJS43583.1 - 0.064 14.2 0.0 4.1 8.4 0.0 3.1 1 1 1 2 2 2 0 WD domain, G-beta repeat DIE2_ALG10 PF04922.12 EJS43584.1 - 5.8e-110 368.3 34.7 9e-110 367.6 34.7 1.3 1 0 0 1 1 1 1 DIE2/ALG10 family SMI1_KNR4 PF09346.10 EJS43585.1 - 4.9e-33 114.3 1.3 2.6e-32 112.0 0.0 2.7 2 1 1 3 3 3 1 SMI1 / KNR4 family (SUKH-1) Band_7 PF01145.25 EJS43586.1 - 1.4e-21 77.3 1.5 2.1e-21 76.7 1.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ank_2 PF12796.7 EJS43587.1 - 8.4e-37 125.6 0.0 7.9e-14 52.0 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJS43587.1 - 1.6e-26 92.3 5.2 2.9e-07 30.9 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJS43587.1 - 7e-24 81.3 0.0 0.00094 19.5 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EJS43587.1 - 9.7e-22 76.8 0.0 0.00013 22.2 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EJS43587.1 - 1e-18 66.8 0.0 0.0074 16.7 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat SCAB-PH PF17684.1 EJS43587.1 - 0.006 16.8 0.0 0.0094 16.2 0.0 1.4 1 0 0 1 1 1 1 PH domain of plant-specific actin-binding protein NMT1_2 PF13379.6 EJS43587.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family ApoO PF09769.9 EJS43588.1 - 1.8e-30 105.5 0.0 3.8e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Apolipoprotein O GCN5L1 PF06320.13 EJS43588.1 - 0.02 15.0 0.1 0.066 13.4 0.0 1.8 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) PFK PF00365.20 EJS43591.1 - 2.2e-184 611.3 1.7 8.6e-105 350.1 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 EJS43591.1 - 2.6e-27 95.1 0.1 6.8e-27 93.8 0.1 1.8 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 EJS43591.1 - 0.015 14.9 0.1 0.08 12.6 0.1 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain ANTH PF07651.16 EJS43592.1 - 1.8e-70 237.1 3.0 1.8e-70 237.1 3.0 1.6 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 EJS43592.1 - 1.9e-08 34.4 0.2 1.9e-08 34.4 0.2 2.1 3 0 0 3 3 3 1 ENTH domain MPC PF03650.13 EJS43593.1 - 3.1e-48 162.5 0.1 3.9e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers ATP-grasp_2 PF08442.10 EJS43594.1 - 2.4e-79 265.6 0.3 4.1e-79 264.9 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EJS43594.1 - 2.7e-27 95.4 0.3 7.6e-27 94.0 0.1 1.9 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 EJS43594.1 - 9.1e-08 31.8 0.1 1.5e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EJS43594.1 - 0.0009 19.1 0.0 0.0057 16.5 0.0 2.0 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SDA1 PF05285.12 EJS43595.1 - 7.2e-93 311.8 36.6 7.2e-93 311.8 36.6 2.0 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 EJS43595.1 - 8.4e-21 74.0 2.8 8.8e-21 74.0 0.7 2.2 2 0 0 2 2 2 1 NUC130/3NT domain EF-hand_14 PF17959.1 EJS43595.1 - 0.05 13.9 0.0 0.22 11.9 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain CPDase PF07823.11 EJS43596.1 - 5e-90 300.5 0.1 5.7e-90 300.4 0.1 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EJS43596.1 - 0.0013 18.7 0.0 0.0027 17.6 0.0 1.5 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Glucosamine_iso PF01182.20 EJS43597.1 - 2.5e-57 194.4 0.0 2.8e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RRM_1 PF00076.22 EJS43598.1 - 1.1e-32 111.7 0.2 2.4e-12 46.5 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOP19 PF10863.8 EJS43599.1 - 2.6e-60 202.4 9.3 4.2e-60 201.7 9.3 1.3 1 0 0 1 1 1 1 Nucleolar protein 19 Dishevelled PF02377.15 EJS43599.1 - 0.08 13.4 4.9 0.16 12.5 4.9 1.5 1 1 0 1 1 1 0 Dishevelled specific domain Bromodomain PF00439.25 EJS43600.1 - 9.4e-28 96.1 2.9 2e-27 95.0 2.9 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EJS43600.1 - 1.5e-09 38.1 0.0 3.1e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJS43600.1 - 3.5e-06 27.0 0.0 7.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJS43600.1 - 0.00031 21.1 0.1 0.00065 20.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Proteasome PF00227.26 EJS43601.1 - 1.4e-53 181.2 0.0 1.8e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJS43601.1 - 1.9e-12 46.6 0.0 5.3e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Enolase_C PF00113.22 EJS43602.1 - 7e-150 498.2 0.0 1.1e-149 497.6 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EJS43602.1 - 1.3e-55 187.1 0.3 2.3e-55 186.3 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EJS43602.1 - 1.3e-06 28.2 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EJS43602.1 - 0.01 15.0 0.6 0.056 12.6 0.1 2.0 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus FAD_binding_3 PF01494.19 EJS43603.1 - 2.8e-18 66.3 0.4 2.9e-12 46.5 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EJS43603.1 - 2.9e-05 23.4 0.0 0.0011 18.3 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EJS43603.1 - 0.00028 20.0 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 EJS43603.1 - 0.0014 17.8 0.0 0.0064 15.6 0.0 2.0 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 EJS43603.1 - 0.0037 16.5 0.0 0.007 15.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EJS43603.1 - 0.019 14.2 0.0 0.33 10.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJS43603.1 - 0.028 14.7 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EJS43603.1 - 0.032 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EJS43603.1 - 0.075 11.9 0.0 0.64 8.8 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 EJS43603.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein HU-HIG PF18291.1 EJS43603.1 - 0.14 12.3 0.1 12 6.0 0.0 2.3 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Pyr_redox PF00070.27 EJS43603.1 - 0.15 12.6 0.0 3.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Endopep_inhib PF16800.5 EJS43603.1 - 0.17 11.8 1.2 0.29 11.1 0.1 1.9 2 0 0 2 2 2 0 IseA DL-endopeptidase inhibitor NAD_binding_9 PF13454.6 EJS43603.1 - 0.18 11.8 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 EJS43603.1 - 0.18 11.3 0.0 0.8 9.2 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase 6PGD PF00393.19 EJS43604.1 - 9.7e-124 412.4 0.0 1.2e-123 412.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EJS43604.1 - 1.1e-50 171.9 0.0 1.6e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EJS43604.1 - 0.11 11.8 0.1 0.26 10.6 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 EJS43604.1 - 0.16 12.2 0.0 0.44 10.8 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 EJS43604.1 - 0.22 11.4 0.1 0.54 10.1 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XPG_N PF00752.17 EJS43605.1 - 2.2e-36 124.3 0.2 6e-36 123.0 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 EJS43605.1 - 9.8e-27 93.2 0.0 4.5e-26 91.0 0.0 2.3 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EJS43605.1 - 0.0007 19.1 0.0 0.002 17.6 0.0 1.8 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EJS43605.1 - 0.0033 18.0 0.0 0.013 16.0 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold KilA-N PF04383.13 EJS43605.1 - 0.091 12.6 1.0 3.1 7.7 0.1 2.8 2 0 0 2 2 2 0 KilA-N domain DUF5511 PF17630.2 EJS43605.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5511) MFS_1 PF07690.16 EJS43606.1 - 2.9e-33 115.3 25.1 3.6e-33 115.0 24.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Kdo PF06293.14 EJS43607.1 - 2.9e-08 33.3 0.0 4.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EJS43607.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EJS43607.1 - 0.0017 18.3 0.1 0.28 11.1 0.2 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EJS43607.1 - 0.04 13.2 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Say1_Mug180 PF10340.9 EJS43608.1 - 1.5e-156 521.0 2.0 1.7e-156 520.8 2.0 1.0 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EJS43608.1 - 2.2e-14 53.8 0.0 3.1e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold VMA21 PF09446.10 EJS43608.1 - 0.15 12.2 0.7 1.2 9.3 0.2 2.4 2 0 0 2 2 2 0 VMA21-like domain tRNA-synt_1g PF09334.11 EJS43609.1 - 1.7e-157 524.2 0.5 2.3e-157 523.7 0.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.10 EJS43609.1 - 6.5e-52 175.2 2.9 6.5e-52 175.2 2.9 1.8 2 0 0 2 2 2 1 MetRS-N binding domain tRNA-synt_1 PF00133.22 EJS43609.1 - 2.6e-09 35.9 0.6 0.00065 18.1 0.4 2.5 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Sigma54_CBD PF04963.13 EJS43609.1 - 0.028 14.3 0.5 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain GTP_cyclohydroI PF01227.22 EJS43610.1 - 4.8e-75 250.9 0.1 5.8e-75 250.6 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EJS43610.1 - 1.8e-05 24.8 0.0 6.1e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein OmpH PF03938.14 EJS43610.1 - 0.021 15.2 0.8 3.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DnaJ_CXXCXGXG PF00684.19 EJS43611.1 - 2.8e-07 30.8 3.6 0.0059 16.9 0.2 2.3 2 0 0 2 2 2 2 DnaJ central domain DZR PF12773.7 EJS43611.1 - 0.042 13.9 3.3 0.69 10.0 0.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 EJS43611.1 - 0.056 13.5 2.3 0.74 9.9 0.4 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2318 PF10080.9 EJS43611.1 - 0.85 9.8 2.8 0.44 10.7 0.3 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) zf-RING_5 PF14634.6 EJS43611.1 - 2.2 8.3 7.1 17 5.5 0.2 2.7 2 1 1 3 3 3 0 zinc-RING finger domain SCIMP PF15050.6 EJS43611.1 - 2.3 8.7 3.7 3.6 8.1 3.7 1.2 1 0 0 1 1 1 0 SCIMP protein DUF2406 PF10295.9 EJS43612.1 - 9.2e-25 87.1 0.5 1.9e-24 86.1 0.5 1.6 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) UN_NPL4 PF11543.8 EJS43612.1 - 0.093 13.2 0.1 0.36 11.3 0.0 1.9 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Rtt102p PF09510.10 EJS43613.1 - 2.2e-47 160.5 1.2 2.7e-47 160.3 1.2 1.1 1 0 0 1 1 1 1 Rtt102p-like transcription regulator protein MA3 PF02847.17 EJS43614.1 - 4.6e-23 81.4 0.5 4.6e-23 81.4 0.5 2.8 3 0 0 3 3 3 1 MA3 domain G2F PF07474.12 EJS43614.1 - 0.093 12.5 0.5 0.49 10.1 0.3 2.1 2 0 0 2 2 2 0 G2F domain Glyco_hydro_17 PF00332.18 EJS43615.1 - 2.7e-11 43.7 3.4 2.1e-10 40.7 3.4 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 RAP1 PF07218.11 EJS43615.1 - 4.9 5.3 7.9 6 5.0 7.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAP1 PF08601.10 EJS43615.1 - 8.6 6.0 15.2 14 5.3 13.7 1.9 2 0 0 2 2 2 0 Transcription factor PAP1 G-patch PF01585.23 EJS43616.1 - 2.1e-11 43.5 0.0 4.6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EJS43616.1 - 0.0045 17.1 0.0 0.0045 17.1 0.0 3.3 2 1 0 2 2 1 1 G-patch domain Neur_chan_memb PF02932.16 EJS43616.1 - 0.062 13.4 10.0 0.069 13.2 10.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 EJS43616.1 - 0.1 10.9 20.6 0.12 10.7 20.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 EJS43616.1 - 0.57 8.9 17.6 0.84 8.4 17.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GREB1 PF15782.5 EJS43616.1 - 0.65 7.0 11.4 0.72 6.9 11.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 EJS43616.1 - 2.3 6.9 12.9 2.9 6.6 12.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter NPR3 PF03666.13 EJS43616.1 - 3.6 6.3 20.7 4.9 5.8 20.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PPL5 PF18168.1 EJS43616.1 - 4.1 6.6 12.8 7 5.8 12.8 1.5 1 0 0 1 1 1 0 Prim-pol family 5 VIR_N PF15912.5 EJS43616.1 - 4.2 6.9 12.4 6.2 6.3 12.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal SLC12 PF03522.15 EJS43616.1 - 4.4 6.2 19.3 5.6 5.9 19.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Cellulose_synt PF03552.14 EJS43616.1 - 5.2 5.4 7.0 6.2 5.2 7.0 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF913 PF06025.12 EJS43616.1 - 6.1 5.7 9.9 7.9 5.3 9.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.7 EJS43616.1 - 6.4 4.8 18.5 7.4 4.6 18.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein O-antigen_lig PF13425.6 EJS43616.1 - 7.4 5.2 8.1 8.9 5.0 8.1 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Hydin_ADK PF17213.3 EJS43616.1 - 9.1 6.5 10.9 15 5.8 10.9 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Zip PF02535.22 EJS43616.1 - 10 5.3 17.9 14 4.7 17.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_17 PF00332.18 EJS43617.1 - 4.3e-100 335.3 4.8 5e-100 335.1 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Methyltrn_RNA_3 PF02598.17 EJS43618.1 - 1.1e-59 202.3 0.0 1.3e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SURF4 PF02077.15 EJS43619.1 - 4.5e-109 364.2 12.0 5.2e-109 364.0 12.0 1.0 1 0 0 1 1 1 1 SURF4 family RAC_head PF16717.5 EJS43620.1 - 1.7e-22 80.2 7.2 1.7e-22 80.2 7.2 3.9 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 EJS43620.1 - 5.9e-16 58.4 0.1 2.1e-15 56.6 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain BATS PF06968.13 EJS43621.1 - 1.5e-23 82.8 0.0 3.9e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EJS43621.1 - 4.6e-16 59.6 0.4 1.6e-15 57.9 0.2 1.8 2 0 0 2 2 2 1 Radical SAM superfamily INPP5B_PH PF16776.5 EJS43621.1 - 0.04 13.6 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain DegV PF02645.16 EJS43621.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 Band_3_cyto PF07565.13 EJS43621.1 - 0.28 10.9 2.5 22 4.7 0.1 2.9 2 1 1 3 3 3 0 Band 3 cytoplasmic domain Cyclin_N PF00134.23 EJS43622.1 - 1.4e-39 134.7 0.2 5e-39 132.9 0.2 2.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EJS43622.1 - 2.4e-29 101.8 0.0 5.8e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain TLD PF07534.16 EJS43623.1 - 0.035 14.3 0.3 0.13 12.5 0.1 2.0 2 0 0 2 2 2 0 TLD SURF1 PF02104.15 EJS43624.1 - 2.1e-43 148.6 0.0 2.8e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family DUF5634 PF18681.1 EJS43624.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5634) Reovirus_Mu2 PF07781.11 EJS43624.1 - 0.14 10.5 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus minor core protein Mu-2 YqgF PF14639.6 EJS43625.1 - 3.6e-69 231.3 0.0 1.2e-68 229.7 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SH2_2 PF14633.6 EJS43625.1 - 1.2e-68 230.7 1.9 3e-68 229.5 1.9 1.7 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 EJS43625.1 - 1.2e-49 166.9 0.2 4.1e-49 165.3 0.2 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 EJS43625.1 - 3.8e-36 124.0 2.0 3.8e-36 124.0 2.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 EJS43625.1 - 7.7e-20 71.3 20.3 7.7e-20 71.3 20.3 5.6 5 1 1 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.24 EJS43625.1 - 5e-14 52.1 0.1 2.1e-13 50.1 0.1 2.2 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 EJS43625.1 - 0.00068 20.5 0.8 0.00068 20.5 0.8 4.0 4 1 0 4 4 4 1 HHH domain DUF3417 PF11897.8 EJS43625.1 - 0.21 12.1 5.0 5.1 7.6 0.2 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) Nup54 PF13874.6 EJS43626.1 - 1.2e-35 122.7 5.1 1.2e-35 122.7 5.1 2.7 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 EJS43626.1 - 8.6e-23 81.0 141.6 1.9e-10 41.4 24.5 4.8 1 1 4 5 5 5 5 Nucleoporin FG repeat region COG2 PF06148.11 EJS43627.1 - 7.7e-10 39.0 7.6 7.9e-10 38.9 5.7 2.1 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin_2 PF14523.6 EJS43627.1 - 0.011 16.1 4.9 3 8.3 2.4 3.0 2 1 1 3 3 3 0 Syntaxin-like protein DHR10 PF18595.1 EJS43627.1 - 0.028 14.5 1.0 0.064 13.3 1.0 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Csm2_III-A PF03750.13 EJS43627.1 - 0.03 15.1 0.3 0.068 14.0 0.3 1.5 1 0 0 1 1 1 0 Csm2 Type III-A LOH1CR12 PF10158.9 EJS43627.1 - 0.055 13.5 2.6 0.16 12.0 0.9 2.3 1 1 2 3 3 3 0 Tumour suppressor protein Fib_alpha PF08702.10 EJS43627.1 - 0.5 10.5 4.1 0.33 11.2 2.0 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5355 PF17306.2 EJS43628.1 - 9.6e-109 363.4 7.1 1.2e-108 363.0 7.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5355) Metallophos PF00149.28 EJS43629.1 - 1.8e-33 116.7 0.1 2.9e-33 116.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EJS43629.1 - 5e-24 84.4 0.2 7.7e-23 80.6 0.0 2.4 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_2 PF07719.17 EJS43629.1 - 3.8e-15 54.7 3.3 5.9e-05 22.9 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EJS43629.1 - 1.4e-12 46.8 5.5 5.5e-06 26.0 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EJS43629.1 - 6.1e-09 35.4 0.0 0.00038 20.1 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 EJS43629.1 - 1.5e-05 25.0 0.0 0.0079 16.3 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EJS43629.1 - 3e-05 24.1 1.1 0.45 11.0 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EJS43629.1 - 0.00011 22.2 0.1 0.12 12.5 0.0 2.8 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 EJS43629.1 - 0.00039 20.4 2.8 2.2 8.7 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EJS43629.1 - 0.0014 19.0 4.3 0.0019 18.7 0.8 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EJS43629.1 - 0.023 15.5 0.3 5.8 8.0 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Asn_synthase PF00733.21 EJS43630.1 - 1.1e-94 318.0 0.5 1.3e-54 186.3 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EJS43630.1 - 1.3e-33 115.5 0.0 2.1e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EJS43630.1 - 1.5e-26 93.2 0.0 4.7e-26 91.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EJS43630.1 - 2.3e-07 30.5 0.0 4.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EJS43630.1 - 0.0033 16.6 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD synthase Sulfate_transp PF00916.20 EJS43631.1 - 2.3e-92 309.7 24.2 3.6e-92 309.1 24.2 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EJS43631.1 - 8.1e-17 60.9 1.2 1.6e-16 59.9 1.2 1.6 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 EJS43631.1 - 0.00023 21.2 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Utp8 PF10395.9 EJS43633.1 - 3.6e-237 789.2 32.3 4.3e-237 789.0 32.3 1.0 1 0 0 1 1 1 1 Utp8 family SYF2 PF08231.12 EJS43634.1 - 2.9e-12 47.3 17.4 2.9e-12 47.3 17.4 1.4 2 0 0 2 2 2 1 SYF2 splicing factor Poxvirus PF06227.12 EJS43634.1 - 0.025 14.4 4.1 0.042 13.6 4.1 1.4 1 0 0 1 1 1 0 dsDNA Poxvirus Chordopox_G3 PF06129.12 EJS43634.1 - 0.038 14.7 1.6 0.052 14.3 0.5 1.8 2 0 0 2 2 2 0 Chordopoxvirus G3 protein SNAD2 PF18745.1 EJS43634.1 - 0.11 12.2 2.9 0.076 12.7 0.8 1.7 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 DUF1525 PF07511.11 EJS43634.1 - 0.24 11.5 2.1 0.35 11.0 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1525) MARVEL PF01284.23 EJS43636.1 - 1.7e-28 99.5 11.7 2e-28 99.2 11.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF1218 PF06749.12 EJS43636.1 - 0.0065 17.0 1.7 0.0065 17.0 1.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1218) DUF3844 PF12955.7 EJS43636.1 - 0.13 12.4 1.1 0.19 11.9 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) Band_7 PF01145.25 EJS43637.1 - 5.4e-24 85.2 5.1 1e-23 84.2 5.1 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EJS43637.1 - 0.0014 17.8 1.1 0.0018 17.4 1.1 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 EJS43637.1 - 0.0064 16.2 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Pinin_SDK_memA PF04696.13 EJS43637.1 - 0.045 13.8 0.4 0.078 13.0 0.1 1.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Proteasome PF00227.26 EJS43639.1 - 7.5e-58 195.2 0.6 9.2e-58 194.9 0.6 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJS43639.1 - 4.7e-12 45.4 1.2 8.4e-12 44.5 0.2 2.1 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature SH3_1 PF00018.28 EJS43640.1 - 5.1e-17 61.2 0.0 1e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJS43640.1 - 3.8e-13 49.1 0.0 6.2e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJS43640.1 - 1.5e-10 40.6 0.0 2.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Suf PF05843.14 EJS43640.1 - 0.19 11.6 3.3 0.2 11.6 3.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 EJS43640.1 - 0.69 9.8 7.3 0.75 9.7 7.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit G_path_suppress PF15991.5 EJS43640.1 - 0.92 9.6 15.2 1.1 9.3 15.2 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor PRCC PF10253.9 EJS43640.1 - 1.1 10.0 13.3 1.9 9.2 13.3 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MFS_1 PF07690.16 EJS43641.1 - 6.4e-32 110.8 31.9 6.4e-32 110.8 31.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GAGA_bind PF06217.12 EJS43642.1 - 0.56 10.4 13.2 0.16 12.2 10.0 1.8 2 0 0 2 2 2 0 GAGA binding protein-like family Draxin PF15550.6 EJS43642.1 - 1.6 8.5 19.7 0.37 10.6 16.2 1.6 2 0 0 2 2 2 0 Draxin KaiA PF07688.12 EJS43642.1 - 5.7 7.1 9.6 0.081 13.1 1.4 2.1 2 0 0 2 2 2 0 KaiA C-terminal domain Pkinase PF00069.25 EJS43643.1 - 1.1e-67 228.1 0.0 1.4e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43643.1 - 9.9e-33 113.5 0.0 1.7e-32 112.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43643.1 - 1.8e-05 24.2 0.1 3.6e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EJS43643.1 - 0.00056 19.3 0.1 0.00091 18.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EJS43643.1 - 0.015 15.2 0.2 0.057 13.3 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EJS43643.1 - 0.042 13.5 0.2 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2439 PF10382.9 EJS43645.1 - 6.5e-22 77.7 0.5 1.2e-21 76.8 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Tam41_Mmp37 PF09139.11 EJS43646.1 - 1.4e-90 304.0 9.4 9.6e-84 281.6 2.2 2.1 1 1 1 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial UFD1 PF03152.14 EJS43647.1 - 6.9e-70 234.0 0.0 9.9e-70 233.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Pkinase PF00069.25 EJS43649.1 - 7.7e-47 159.9 0.0 1.2e-46 159.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43649.1 - 2.2e-25 89.4 0.0 3.4e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43649.1 - 1.3e-05 24.7 0.0 2.9e-05 23.5 0.0 1.5 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EJS43649.1 - 0.0029 17.5 0.0 2 8.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family WYL_3 PF18488.1 EJS43649.1 - 0.1 13.0 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 WYL domain eIF2A PF08662.11 EJS43650.1 - 1.3e-75 253.5 0.1 5.4e-75 251.5 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EJS43650.1 - 0.0015 19.4 3.0 3 8.9 0.1 4.7 3 2 1 4 4 4 1 WD domain, G-beta repeat ORC6 PF05460.13 EJS43650.1 - 2 7.6 7.0 3.1 7.0 7.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) EF-hand_7 PF13499.6 EJS43651.1 - 1.2e-10 41.7 0.6 2.3e-05 24.7 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EJS43651.1 - 3.7e-08 32.7 1.7 0.016 15.1 0.1 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EJS43651.1 - 0.00016 21.0 0.1 5.7 6.7 0.0 4.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EJS43651.1 - 0.00094 19.0 0.1 4.9 7.1 0.0 3.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EJS43651.1 - 0.0056 16.1 0.7 9 6.0 0.0 3.8 4 0 0 4 4 4 2 EF hand Septin PF00735.18 EJS43652.1 - 3.1e-101 338.4 1.4 3.1e-101 338.4 1.4 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EJS43652.1 - 3.4e-05 23.9 0.1 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJS43652.1 - 6.6e-05 22.9 4.8 0.0024 17.8 0.3 3.3 3 1 0 3 3 3 2 RsgA GTPase AIG1 PF04548.16 EJS43652.1 - 0.00098 18.5 1.2 0.0037 16.6 0.0 2.4 2 0 0 2 2 2 1 AIG1 family CCDC92 PF14916.6 EJS43652.1 - 0.0034 17.1 1.3 0.014 15.2 1.3 2.1 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Gtr1_RagA PF04670.12 EJS43652.1 - 0.007 15.7 0.7 0.027 13.8 0.1 2.3 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region YxiJ PF14176.6 EJS43652.1 - 0.0071 16.8 0.6 0.0071 16.8 0.6 2.3 2 0 0 2 2 2 1 YxiJ-like protein AAA_24 PF13479.6 EJS43652.1 - 0.037 13.7 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glyco_hydro_77 PF02446.17 EJS43652.1 - 1.8 7.3 7.1 2.6 6.8 7.1 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase FA_hydroxylase PF04116.13 EJS43653.1 - 1.1e-26 93.7 18.8 1.1e-26 93.7 18.8 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily GATase_5 PF13507.6 EJS43654.1 - 1.3e-100 335.8 0.0 2e-100 335.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EJS43654.1 - 1.3e-43 148.8 0.2 9.2e-31 107.1 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EJS43654.1 - 1.2e-27 96.2 0.0 2.2e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EJS43654.1 - 3.9e-22 78.5 0.2 1.7e-21 76.4 0.1 2.3 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain 60KD_IMP PF02096.20 EJS43655.1 - 3.3e-07 30.4 4.7 3.3e-07 30.4 4.7 2.3 2 1 0 2 2 2 2 60Kd inner membrane protein F-box-like_2 PF13013.6 EJS43655.1 - 0.078 13.0 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain Spt4 PF06093.13 EJS43656.1 - 8.1e-29 99.5 0.6 9.5e-29 99.3 0.6 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TackOD1 PF18551.1 EJS43656.1 - 0.062 13.0 1.2 0.084 12.5 1.2 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Vac_ImportDeg PF09783.9 EJS43657.1 - 3.9e-46 156.8 0.2 4.8e-46 156.5 0.2 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Arrestin_C PF02752.22 EJS43658.1 - 8.8e-20 71.5 0.7 1.8e-19 70.6 0.1 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EJS43658.1 - 2.3e-05 24.5 0.2 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain CNH PF00780.22 EJS43659.1 - 3.1e-55 187.7 0.3 5.5e-55 186.9 0.3 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 EJS43659.1 - 4.7e-37 127.1 0.2 4.7e-37 127.1 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.20 EJS43659.1 - 5.5e-27 95.2 0.2 5.5e-27 95.2 0.2 2.6 3 0 0 3 3 3 1 RhoGEF domain DEP PF00610.21 EJS43659.1 - 3.2e-09 36.7 0.0 8.9e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1327 PF07041.11 EJS43659.1 - 0.019 15.0 0.0 0.057 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) Smg4_UPF3 PF03467.15 EJS43660.1 - 7.8e-34 117.2 3.0 7.8e-34 117.2 3.0 3.2 2 2 1 3 3 3 1 Smg-4/UPF3 family Dsh_C PF12316.8 EJS43660.1 - 9.2 6.6 18.2 5.2 7.4 4.7 2.3 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal LSM PF01423.22 EJS43661.1 - 1.1e-25 89.0 0.2 1.6e-25 88.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EJS43661.1 - 0.0024 18.0 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF148 PF02520.17 EJS43661.1 - 0.022 14.8 0.1 0.037 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 Mitoc_mL59 PF18126.1 EJS43662.1 - 7.4e-27 94.2 0.1 9.5e-27 93.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Prefoldin PF02996.17 EJS43664.1 - 3.7e-37 126.9 0.1 5.3e-37 126.4 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EJS43664.1 - 0.0028 17.6 2.2 0.28 11.2 0.0 2.4 2 0 0 2 2 2 2 Prefoldin subunit Pox_A_type_inc PF04508.12 EJS43664.1 - 0.048 13.5 0.5 0.15 11.9 0.5 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SNAD4 PF18750.1 EJS43664.1 - 0.1 12.7 0.1 0.38 10.9 0.0 1.9 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 CENP-F_leu_zip PF10473.9 EJS43664.1 - 0.18 11.8 4.7 3.7 7.6 0.9 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 EJS43664.1 - 0.34 11.3 2.5 4.8 7.6 0.5 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family Csm1_N PF18504.1 EJS43664.1 - 0.69 10.3 3.4 2.6 8.4 0.2 2.7 2 1 1 3 3 3 0 Csm1 N-terminal domain Cofilin_ADF PF00241.20 EJS43665.1 - 3.7e-27 94.5 0.0 2.9e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein SLX9 PF15341.6 EJS43666.1 - 6.5e-24 84.8 7.8 1.1e-23 84.0 7.8 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 NinG PF05766.12 EJS43666.1 - 0.12 12.3 0.2 0.12 12.3 0.2 1.8 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein MAS20 PF02064.15 EJS43667.1 - 5.5e-39 133.2 1.0 6.9e-39 132.9 1.0 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor T3SS_ATPase_C PF18269.1 EJS43667.1 - 0.14 12.0 0.8 3.8 7.4 0.2 2.3 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain ImpA_N PF06812.12 EJS43667.1 - 0.24 11.5 1.1 1.5 8.9 1.1 1.9 1 1 0 1 1 1 0 ImpA, N-terminal, type VI secretion system IF-2B PF01008.17 EJS43668.1 - 1.1e-109 366.0 0.1 1.1e-109 366.0 0.1 2.0 2 0 0 2 2 2 1 Initiation factor 2 subunit family DeoRC PF00455.22 EJS43668.1 - 0.049 13.6 5.3 0.16 11.9 0.9 2.8 2 1 0 2 2 2 0 DeoR C terminal sensor domain Atg14 PF10186.9 EJS43668.1 - 2.7 7.0 15.9 5.4 6.0 15.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GREB1 PF15782.5 EJS43668.1 - 8 3.4 15.1 9.8 3.1 15.1 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ribosomal_L5_C PF00673.21 EJS43669.1 - 1.6e-22 79.5 0.0 2.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EJS43669.1 - 6.9e-20 71.1 0.1 2.1e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Pil1 PF13805.6 EJS43670.1 - 1.7e-123 411.3 0.0 2.2e-123 410.9 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 SLT_beta PF02258.16 EJS43670.1 - 0.21 11.7 0.0 0.54 10.3 0.0 1.6 1 0 0 1 1 1 0 Shiga-like toxin beta subunit TPP_enzyme_N PF02776.18 EJS43671.1 - 1.6e-30 105.9 0.0 2.8e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EJS43671.1 - 3.3e-25 88.4 0.0 2.9e-24 85.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EJS43671.1 - 7.8e-13 48.5 0.0 1.7e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain LRR_3 PF07725.12 EJS43671.1 - 0.47 10.4 2.0 0.7 9.8 0.2 2.2 2 0 0 2 2 2 0 Leucine Rich Repeat DivIC PF04977.15 EJS43672.1 - 0.0087 15.8 4.7 0.0087 15.8 4.7 4.8 5 0 0 5 5 5 1 Septum formation initiator Laminin_II PF06009.12 EJS43672.1 - 0.069 13.2 22.5 3.7 7.5 7.2 2.9 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 EJS43672.1 - 0.18 11.8 18.3 0.35 10.9 7.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 EJS43672.1 - 0.2 9.1 26.0 0.3 8.5 26.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RasGAP_C PF03836.15 EJS43672.1 - 1.4 9.1 34.1 0.019 15.1 10.4 3.7 2 1 2 4 4 4 0 RasGAP C-terminus DUF3450 PF11932.8 EJS43672.1 - 7.6 5.8 22.7 1.7 7.9 4.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SpecificRecomb PF10136.9 EJS43672.1 - 7.8 4.7 7.3 21 3.3 6.8 1.8 1 1 0 1 1 1 0 Site-specific recombinase Nrap_D5 PF17406.2 EJS43673.1 - 6.1e-52 175.7 0.0 1.4e-51 174.5 0.0 1.7 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 EJS43673.1 - 3.3e-50 169.8 1.4 1.2e-48 164.7 0.8 2.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 EJS43673.1 - 9.8e-49 165.6 0.1 1.8e-48 164.7 0.1 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 EJS43673.1 - 2.2e-44 151.1 3.9 5e-44 150.0 3.9 1.6 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 EJS43673.1 - 1.3e-40 139.1 0.5 2.8e-40 138.0 0.0 1.8 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EJS43673.1 - 3e-27 95.5 0.1 8e-27 94.1 0.1 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 Dynactin_p22 PF07426.11 EJS43673.1 - 2.5 7.9 8.8 8.9 6.1 0.2 3.9 4 0 0 4 4 4 0 Dynactin subunit p22 Pkinase PF00069.25 EJS43674.1 - 2e-57 194.6 0.0 1.1e-56 192.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43674.1 - 1.2e-28 100.1 0.5 4.9e-20 71.9 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EJS43674.1 - 0.00016 22.3 2.0 0.00059 20.5 2.0 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EJS43674.1 - 0.0019 17.2 0.8 0.0051 15.8 0.8 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EJS43674.1 - 0.0045 16.4 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EJS43674.1 - 0.0098 15.2 0.0 0.077 12.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EJS43674.1 - 0.12 12.3 0.0 0.73 9.7 0.0 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family CwfJ_C_1 PF04677.15 EJS43675.1 - 1.5e-40 137.8 0.4 3.9e-40 136.5 0.4 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EJS43675.1 - 1.1e-15 58.3 0.2 2.9e-15 56.9 0.2 1.9 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.23 EJS43675.1 - 0.047 14.4 0.0 0.15 12.8 0.0 1.9 1 0 0 1 1 1 0 HIT domain DUF2226 PF09987.9 EJS43675.1 - 0.064 12.6 0.4 0.78 9.0 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) tRNA-synt_1 PF00133.22 EJS43676.1 - 6.5e-240 797.5 0.2 8.1e-239 793.9 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EJS43676.1 - 3.7e-32 111.4 2.7 1.1e-31 109.8 2.7 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EJS43676.1 - 1.2e-15 57.2 0.4 4.8e-09 35.4 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EJS43676.1 - 1.9e-07 30.8 12.6 1.5e-06 27.8 0.0 3.7 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 EJS43676.1 - 3.5e-05 24.0 6.5 3.5e-05 24.0 6.5 2.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 EJS43676.1 - 0.0031 16.9 0.0 1 8.6 0.0 3.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF3450 PF11932.8 EJS43676.1 - 0.17 11.2 7.8 3.6 6.8 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) tRNA-synt_1c PF00749.21 EJS43676.1 - 2.5 6.9 6.0 0.95 8.3 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain Seryl_tRNA_N PF02403.22 EJS43676.1 - 3.7 7.8 16.4 0.32 11.2 6.3 3.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain tRNA-synt_1b PF00579.25 EJS43676.1 - 4.6 6.5 6.4 0.98 8.7 0.0 2.8 4 0 0 4 4 4 0 tRNA synthetases class I (W and Y) RNase_PH PF01138.21 EJS43677.1 - 1.3e-16 61.3 0.0 2.4e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EJS43677.1 - 1.3e-09 37.9 0.4 2.7e-09 36.9 0.3 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 AAA_lid_5 PF17865.1 EJS43677.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Midasin AAA lid domain Mito_carr PF00153.27 EJS43678.1 - 1.3e-62 207.7 4.9 1.4e-21 76.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EJS43678.1 - 3.7e-05 23.0 0.5 0.11 11.7 0.0 3.3 3 0 0 3 3 3 3 Gammaproteobacterial serine protease PH PF00169.29 EJS43679.1 - 0.02 15.4 0.2 0.79 10.3 0.1 3.0 2 1 0 2 2 2 0 PH domain Peptidase_C50 PF03568.17 EJS43680.1 - 4.6e-133 444.2 0.1 9.6e-133 443.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase family C50 Telomere_reg-2 PF10193.9 EJS43681.1 - 1e-20 74.2 1.2 2.7e-20 72.8 0.2 2.2 2 0 0 2 2 2 1 Telomere length regulation protein NOA36 PF06524.12 EJS43681.1 - 2.5 7.4 5.2 4 6.7 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein RabGAP-TBC PF00566.18 EJS43682.1 - 2.5e-52 177.6 0.7 2.5e-52 177.6 0.7 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 EJS43682.1 - 3.9e-19 68.6 0.2 9.2e-19 67.4 0.2 1.7 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 EJS43682.1 - 6.4e-06 25.7 1.1 0.0011 18.7 0.1 3.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EJS43682.1 - 3.8e-05 24.1 0.7 0.0011 19.4 0.4 3.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 EJS43682.1 - 0.037 13.6 0.1 0.13 11.9 0.1 2.0 1 0 0 1 1 1 0 EF hand Vps36_ESCRT-II PF11605.8 EJS43682.1 - 0.081 13.1 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DUF2252 PF10009.9 EJS43682.1 - 0.18 10.9 2.2 0.47 9.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) Rhomboid PF01694.22 EJS43683.1 - 1.2e-31 109.8 16.4 1.2e-31 109.8 16.4 1.7 2 0 0 2 2 2 1 Rhomboid family Pescadillo_N PF06732.11 EJS43685.1 - 1.9e-123 411.3 0.9 1.9e-123 411.3 0.9 2.6 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT_2 PF16589.5 EJS43685.1 - 9.1e-11 42.0 0.0 3.9e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EJS43685.1 - 0.00053 20.3 0.4 0.0018 18.6 0.0 2.2 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EJS43685.1 - 0.023 15.0 0.1 0.16 12.3 0.0 2.5 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Med18 PF09637.10 EJS43686.1 - 7.1e-49 166.9 0.0 7.1e-48 163.6 0.0 1.9 1 1 0 1 1 1 1 Med18 protein VMA21 PF09446.10 EJS43687.1 - 6.7e-10 38.9 17.2 5.6e-09 36.0 17.2 1.9 1 1 0 1 1 1 1 VMA21-like domain DAD PF02109.16 EJS43687.1 - 0.01 16.1 0.2 0.012 15.9 0.2 1.0 1 0 0 1 1 1 0 DAD family DUF3397 PF11877.8 EJS43688.1 - 0.093 12.9 3.9 0.26 11.5 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) ATP-synt_S1 PF05827.12 EJS43688.1 - 0.44 10.4 9.1 0.051 13.4 3.2 2.2 2 1 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Thg1 PF04446.12 EJS43689.1 - 1.1e-47 161.1 0.2 1.5e-47 160.7 0.2 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EJS43689.1 - 1.2e-37 128.7 0.2 2.2e-37 127.9 0.2 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain Ribosomal_S25 PF03297.15 EJS43691.1 - 8.4e-39 131.8 6.1 9.5e-39 131.7 6.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 EJS43691.1 - 0.0002 21.1 0.1 0.00029 20.5 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain EAP30 PF04157.16 EJS43691.1 - 0.035 13.4 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_CodY PF08222.11 EJS43691.1 - 0.057 13.0 0.2 0.09 12.3 0.2 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain AAA PF00004.29 EJS43692.1 - 2.4e-39 134.8 0.0 3.9e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS43692.1 - 1.5e-11 43.9 0.1 3.4e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 EJS43692.1 - 1e-06 28.8 0.0 2.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJS43692.1 - 2.7e-06 27.9 0.1 0.00023 21.6 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EJS43692.1 - 2.9e-06 27.1 0.0 7.9e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EJS43692.1 - 3.1e-06 27.2 0.2 5.7e-05 23.1 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EJS43692.1 - 4.8e-06 26.8 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EJS43692.1 - 1.4e-05 25.4 0.3 0.003 17.8 0.0 3.1 1 1 2 3 3 3 1 AAA domain AAA_18 PF13238.6 EJS43692.1 - 8.7e-05 23.1 0.0 0.00018 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EJS43692.1 - 0.00026 21.2 0.0 0.00082 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EJS43692.1 - 0.00041 19.8 0.0 0.97 8.8 0.0 2.3 1 1 1 2 2 2 2 Bacterial TniB protein Sigma54_activ_2 PF14532.6 EJS43692.1 - 0.00053 20.1 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 EJS43692.1 - 0.00059 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EJS43692.1 - 0.00068 19.1 0.2 0.0018 17.7 0.2 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EJS43692.1 - 0.00071 19.9 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.13 EJS43692.1 - 0.00084 18.6 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Rad17 PF03215.15 EJS43692.1 - 0.0012 18.8 0.1 0.0044 17.0 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain Bac_DnaA PF00308.18 EJS43692.1 - 0.0019 18.1 0.0 0.0044 16.9 0.0 1.5 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_24 PF13479.6 EJS43692.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EJS43692.1 - 0.0053 16.7 0.1 0.015 15.2 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 EJS43692.1 - 0.0069 15.9 0.0 0.027 14.0 0.0 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 EJS43692.1 - 0.0075 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EJS43692.1 - 0.0076 16.8 0.0 0.022 15.3 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_17 PF13207.6 EJS43692.1 - 0.0081 16.6 0.0 0.021 15.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 EJS43692.1 - 0.0091 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.13 EJS43692.1 - 0.0093 15.2 0.1 0.025 13.8 0.1 1.6 1 1 1 2 2 2 1 TIP49 P-loop domain Hydin_ADK PF17213.3 EJS43692.1 - 0.011 16.1 0.1 0.91 9.8 0.0 2.6 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain AAA_25 PF13481.6 EJS43692.1 - 0.013 15.0 0.1 0.06 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EJS43692.1 - 0.014 14.7 0.4 2 7.6 0.0 2.7 2 1 1 3 3 3 0 KAP family P-loop domain Sigma54_activat PF00158.26 EJS43692.1 - 0.014 15.1 0.0 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EJS43692.1 - 0.026 14.4 0.0 0.16 11.9 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 EJS43692.1 - 0.028 14.3 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EJS43692.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EJS43692.1 - 0.039 13.7 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 EJS43692.1 - 0.043 12.9 0.1 0.087 11.9 0.0 1.5 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 IPT PF01745.16 EJS43692.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase Alba PF01918.21 EJS43693.1 - 2.7e-12 46.3 0.1 4.3e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Alba Glucan_synthase PF02364.15 EJS43694.1 - 0 1344.8 0.0 0 1344.2 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EJS43694.1 - 3.5e-43 147.0 0.2 1.4e-42 145.1 0.2 2.1 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TIM21 PF08294.11 EJS43695.1 - 2.9e-58 195.9 0.1 4.1e-58 195.4 0.1 1.2 1 0 0 1 1 1 1 TIM21 Otopetrin PF03189.13 EJS43695.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Otopetrin KASH PF10541.9 EJS43696.1 - 0.095 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear envelope localisation domain PAP2 PF01569.21 EJS43697.1 - 1.6e-19 70.0 0.7 1.6e-19 70.0 0.7 1.5 2 0 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EJS43697.1 - 0.11 12.7 0.2 0.88 9.7 0.0 2.1 2 0 0 2 2 2 0 Divergent PAP2 family ACBP PF00887.19 EJS43698.1 - 3.2e-29 101.0 0.7 3.5e-29 100.8 0.7 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 EJS43698.1 - 0.082 13.3 0.1 2.3 8.6 0.0 2.0 1 1 1 2 2 2 0 FERM central domain ORMDL PF04061.14 EJS43699.1 - 4e-56 188.6 3.8 4.8e-56 188.3 3.8 1.1 1 0 0 1 1 1 1 ORMDL family DUF3498 PF12004.8 EJS43699.1 - 0.025 13.8 0.3 0.032 13.4 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) PI3K_C2 PF00792.24 EJS43699.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Pyridox_oxase_2 PF12766.7 EJS43701.1 - 9.2e-32 109.6 0.2 1.7e-31 108.8 0.2 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PdaC PF13739.6 EJS43701.1 - 0.036 15.0 1.9 0.076 14.0 0.8 2.0 2 1 0 2 2 2 0 Deacetylase PdaC Aminotran_3 PF00202.21 EJS43702.1 - 2.3e-102 342.7 0.0 2.7e-102 342.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ATP-synt_F PF01990.17 EJS43703.1 - 2.5e-32 111.1 0.2 2.8e-32 110.9 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit RRP7 PF12923.7 EJS43703.1 - 0.12 12.5 1.5 0.2 11.8 1.4 1.4 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Mid2 PF04478.12 EJS43704.1 - 8.4e-66 220.4 2.3 8.4e-66 220.4 2.3 3.7 3 2 1 4 4 4 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 EJS43704.1 - 0.0062 15.9 3.9 0.04 13.3 3.9 2.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain HSCB_C PF07743.13 EJS43705.1 - 2.2e-17 63.3 3.6 1.7e-15 57.3 0.6 2.2 2 0 0 2 2 2 2 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EJS43705.1 - 2.1e-09 37.4 0.3 6e-09 35.9 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain M157 PF11624.8 EJS43705.1 - 0.066 12.6 0.2 0.071 12.4 0.2 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 FAM167 PF11652.8 EJS43705.1 - 0.081 13.4 0.4 0.081 13.4 0.4 2.0 2 0 0 2 2 2 0 FAM167 Cortex-I_coil PF09304.10 EJS43705.1 - 0.15 12.3 3.5 0.11 12.7 1.3 1.8 1 1 1 2 2 2 0 Cortexillin I, coiled coil CSRNP_N PF16019.5 EJS43705.1 - 1.5 8.6 4.5 2.4 8.0 4.5 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Exonuc_VII_L PF02601.15 EJS43705.1 - 3.7 7.0 8.0 4.9 6.6 8.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATE_C PF04377.15 EJS43706.1 - 5.2e-45 153.4 0.9 9.7e-45 152.5 0.9 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EJS43706.1 - 2.2e-23 82.4 0.6 4.4e-23 81.5 0.6 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus PHA_synth_III_E PF09712.10 EJS43707.1 - 0.039 13.1 0.0 0.38 9.8 0.1 2.3 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) IBN_N PF03810.19 EJS43707.1 - 0.46 10.4 3.8 0.66 9.9 0.1 3.2 3 0 0 3 3 3 0 Importin-beta N-terminal domain PUF PF00806.19 EJS43708.1 - 8.4e-67 217.3 18.8 8.1e-10 37.9 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Virul_Fac PF10139.9 EJS43708.1 - 0.0041 15.4 0.6 0.0061 14.8 0.6 1.1 1 0 0 1 1 1 1 Putative bacterial virulence factor CPL PF08144.11 EJS43708.1 - 0.018 15.4 0.3 3.7 7.9 0.1 3.9 2 2 0 2 2 2 0 CPL (NUC119) domain V_ATPase_I PF01496.19 EJS43708.1 - 0.26 9.2 5.4 0.43 8.4 5.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SARAF PF06682.12 EJS43708.1 - 2.3 7.8 11.2 4.7 6.8 11.2 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis ERG4_ERG24 PF01222.17 EJS43709.1 - 4.6e-190 631.9 31.7 5.2e-190 631.8 31.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Proteasome PF00227.26 EJS43710.1 - 9.7e-48 162.2 0.0 1.5e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJS43710.1 - 2.1e-15 56.1 0.1 3.8e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF962 PF06127.11 EJS43711.1 - 3.7e-28 97.5 5.1 1.1e-27 95.9 5.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) EMP70 PF02990.16 EJS43711.1 - 0.004 15.9 4.8 0.0051 15.5 4.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Aconitase PF00330.20 EJS43712.1 - 7.9e-158 526.2 0.1 9.6e-158 526.0 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EJS43712.1 - 4.2e-47 159.7 0.0 8.2e-47 158.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain E1-E2_ATPase PF00122.20 EJS43713.1 - 3.7e-49 166.7 4.5 1.1e-48 165.2 3.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EJS43713.1 - 9e-19 68.6 0.1 2.8e-18 67.0 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EJS43713.1 - 2e-11 43.4 0.0 5e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJS43713.1 - 0.0021 17.9 0.1 0.0043 16.8 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJS43713.1 - 0.0042 17.2 0.0 0.0079 16.3 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 EJS43714.1 - 8.6e-43 146.2 8.4 8.6e-43 146.2 8.4 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EJS43714.1 - 1.9e-37 128.6 0.2 1.9e-37 128.6 0.2 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EJS43714.1 - 7.7e-18 65.5 0.1 1.7e-14 54.6 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJS43714.1 - 1.2e-16 60.5 0.1 3.2e-16 59.2 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EJS43714.1 - 3.3e-10 39.5 0.0 1.1e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJS43714.1 - 0.00033 20.5 5.2 0.0009 19.1 0.3 3.1 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJS43714.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 EJS43714.1 - 0.34 9.6 4.3 2 7.1 0.3 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Med11 PF10280.9 EJS43715.1 - 0.0013 19.2 1.7 0.0013 19.2 1.7 1.9 2 1 0 2 2 2 1 Mediator complex protein COG5 PF10392.9 EJS43715.1 - 0.0091 16.2 0.6 0.0091 16.2 0.6 3.1 1 1 2 3 3 3 2 Golgi transport complex subunit 5 CorA PF01544.18 EJS43715.1 - 0.015 14.6 7.4 0.026 13.8 2.8 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Peptidase_M19 PF01244.21 EJS43715.1 - 0.048 12.8 0.1 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) MA3 PF02847.17 EJS43715.1 - 0.14 12.1 1.7 0.71 9.9 0.0 2.7 4 0 0 4 4 4 0 MA3 domain DUF919 PF06034.11 EJS43715.1 - 0.2 11.5 4.1 0.17 11.7 1.7 2.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Laminin_II PF06009.12 EJS43715.1 - 0.24 11.4 8.0 0.13 12.2 4.5 2.3 1 1 1 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.11 EJS43715.1 - 0.6 10.7 12.4 33 5.1 7.1 3.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal WD40 PF00400.32 EJS43716.1 - 5.2e-19 68.2 12.0 0.0015 19.3 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS43716.1 - 7.6e-15 55.0 6.2 1.5e-07 31.6 0.1 4.1 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJS43716.1 - 1.3e-07 31.8 0.6 0.0021 18.0 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EJS43716.1 - 0.071 12.1 0.1 0.99 8.3 0.0 2.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein EMP24_GP25L PF01105.24 EJS43717.1 - 8.6e-49 165.9 0.0 9.9e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CarboxypepD_reg PF13620.6 EJS43717.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain 3Beta_HSD PF01073.19 EJS43718.1 - 5.9e-102 340.4 0.0 7e-102 340.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EJS43718.1 - 4e-33 114.9 0.0 5.3e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EJS43718.1 - 9.6e-23 81.1 0.0 2.8e-22 79.6 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EJS43718.1 - 9.9e-15 54.4 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EJS43718.1 - 1e-12 47.8 0.0 1.7e-11 43.8 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EJS43718.1 - 1.1e-11 45.0 0.0 1.6e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EJS43718.1 - 5.6e-10 38.8 0.0 9.8e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EJS43718.1 - 0.00013 21.9 0.0 0.00041 20.3 0.0 1.8 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EJS43718.1 - 0.0021 17.7 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EJS43718.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SANT_DAMP1_like PF16282.5 EJS43719.1 - 1.3e-26 92.5 5.5 3.5e-26 91.2 5.5 1.8 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1_like PF17024.5 EJS43719.1 - 0.0049 17.0 2.5 0.024 14.8 0.2 2.5 2 0 0 2 2 2 1 Putative DMAP1-like Myb_DNA-binding PF00249.31 EJS43719.1 - 0.021 15.0 0.1 0.07 13.3 0.1 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJS43719.1 - 0.87 9.9 5.8 0.14 12.4 0.6 2.5 2 1 0 3 3 3 0 Myb-like DNA-binding domain FapA PF03961.13 EJS43719.1 - 3.5 6.1 7.8 5.7 5.4 7.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pex24p PF06398.11 EJS43720.1 - 7.3e-86 288.4 13.2 9.5e-86 288.1 13.2 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin B12D PF06522.11 EJS43720.1 - 0.37 10.6 3.1 2 8.3 0.5 2.5 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PhoR PF11808.8 EJS43720.1 - 3.1 8.3 7.5 5 7.6 1.1 2.4 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR TFIIF_beta_N PF17683.1 EJS43721.1 - 2.5e-36 125.3 10.3 2.5e-36 125.3 10.3 2.3 2 1 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EJS43721.1 - 1.9e-27 95.2 0.7 4.3e-27 94.0 0.7 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 EJS43721.1 - 0.005 17.6 1.3 0.005 17.6 1.3 2.3 1 1 1 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain YqaH PF17448.2 EJS43721.1 - 0.17 12.2 0.9 22 5.4 0.1 2.7 1 1 1 2 2 2 0 Uncharacterized YqaH-like GAGA_bind PF06217.12 EJS43721.1 - 0.97 9.7 12.5 1.5 9.0 6.7 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Prp18 PF02840.15 EJS43722.1 - 1e-36 126.1 0.1 1.9e-36 125.3 0.1 1.5 1 0 0 1 1 1 1 Prp18 domain CTP_transf_like PF01467.26 EJS43723.1 - 1.3e-33 116.1 0.2 2.5e-24 86.1 0.1 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EJS43723.1 - 0.026 14.4 2.4 7.5 6.4 0.3 3.1 3 1 0 3 3 3 0 FAD synthetase HABP4_PAI-RBP1 PF04774.15 EJS43724.1 - 0.00089 20.1 1.2 0.00095 20.0 0.7 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family CTP_transf_like PF01467.26 EJS43726.1 - 3.8e-32 111.5 0.0 5.9e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like PALP PF00291.25 EJS43727.1 - 9.5e-66 222.2 0.8 1.1e-65 222.0 0.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FOP_dimer PF09398.10 EJS43728.1 - 0.028 14.7 1.5 0.049 13.9 0.1 2.2 2 0 0 2 2 2 0 FOP N terminal dimerisation domain pXO2-72 PF17443.2 EJS43728.1 - 0.087 13.1 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein pXO2-72 Epimerase PF01370.21 EJS43729.1 - 2.6e-12 46.7 0.0 4.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EJS43729.1 - 6.7e-11 41.7 0.0 8.4e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EJS43729.1 - 8.5e-10 38.2 0.4 9.4e-09 34.8 0.4 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EJS43729.1 - 1.3e-07 31.3 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EJS43729.1 - 1e-05 25.5 0.1 1.9e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EJS43729.1 - 2.1e-05 24.5 0.0 2.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EJS43729.1 - 7.6e-05 22.2 0.4 0.00053 19.5 0.1 2.4 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EJS43729.1 - 0.0016 17.7 0.2 0.0024 17.1 0.2 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KN17_SH3 PF18131.1 EJS43729.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 KN17 SH3-like C-terminal domain Isochorismatase PF00857.20 EJS43730.1 - 3e-25 89.4 0.0 5e-25 88.7 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family DUF771 PF05595.11 EJS43730.1 - 0.054 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF771) zf-H2C2_2 PF13465.6 EJS43731.1 - 1.3e-06 28.6 15.1 5.9e-05 23.3 1.9 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EJS43731.1 - 1.7e-06 28.1 13.6 0.0035 17.7 1.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJS43731.1 - 0.0015 19.2 11.1 0.28 12.2 3.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger SUIM_assoc PF16619.5 EJS43731.1 - 0.078 13.0 8.0 1.9 8.6 0.2 3.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AGA2 PF17366.2 EJS43732.1 - 2.9e-27 94.2 6.5 3.4e-27 93.9 6.5 1.1 1 0 0 1 1 1 1 A-agglutinin-binding subunit Aga2 Ribosomal_L24e PF01246.20 EJS43733.1 - 2.3e-28 98.2 0.2 2.3e-28 98.2 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e Cgr1 PF03879.14 EJS43734.1 - 6.4e-34 116.6 30.4 7.4e-34 116.4 30.4 1.0 1 0 0 1 1 1 1 Cgr1 family DUF2048 PF09752.9 EJS43734.1 - 0.03 13.4 4.6 0.036 13.2 4.6 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Ly49 PF08391.10 EJS43734.1 - 6.4 7.2 7.2 5.5 7.4 6.1 1.5 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region TFIIA PF03153.13 EJS43735.1 - 0.35 10.8 22.8 0.49 10.3 22.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 EJS43735.1 - 0.37 9.4 38.7 0.5 9.0 38.7 1.1 1 0 0 1 1 1 0 Hamartin protein AF-4 PF05110.13 EJS43735.1 - 3.8 5.5 43.4 5 5.1 43.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Glyco_hydro_63 PF03200.16 EJS43736.1 - 5.3e-184 612.6 1.2 1.7e-183 610.9 1.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EJS43736.1 - 7.5e-64 215.9 0.0 1.5e-63 214.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain FlaE PF07559.14 EJS43736.1 - 0.00089 19.8 0.0 0.0027 18.3 0.0 1.9 1 1 0 1 1 1 1 Flagellar basal body protein FlaE Med3 PF11593.8 EJS43737.1 - 1.2e-182 607.6 56.3 1.4e-182 607.5 56.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal CorA PF01544.18 EJS43737.1 - 0.0057 16.0 0.8 0.0098 15.2 0.8 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FYVE PF01363.21 EJS43738.1 - 7.5e-15 54.8 6.0 1.6e-14 53.7 6.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 EJS43738.1 - 2.6 8.3 12.5 12 6.2 12.5 2.1 1 1 1 2 2 2 0 AN1-like Zinc finger STT3 PF02516.14 EJS43739.1 - 3.8e-161 537.3 48.8 6e-159 530.1 45.2 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit CK_II_beta PF01214.18 EJS43740.1 - 1.9e-69 233.1 0.7 4.5e-69 231.9 0.7 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Use1 PF09753.9 EJS43741.1 - 1.4e-11 44.6 2.4 1.8e-11 44.2 2.4 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 RCC1 PF00415.18 EJS43742.1 - 3.4e-63 210.1 0.1 2.7e-08 34.3 0.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EJS43742.1 - 2.6e-38 129.0 21.8 5.4e-08 32.4 0.0 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Sec1 PF00995.23 EJS43743.1 - 8.1e-124 414.9 19.4 9.2e-124 414.8 19.4 1.0 1 0 0 1 1 1 1 Sec1 family GBR2_CC PF18455.1 EJS43743.1 - 0.13 12.4 1.5 12 6.1 0.1 2.8 2 0 0 2 2 2 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain Prp18 PF02840.15 EJS43743.1 - 5.9 6.9 6.2 12 6.0 0.2 3.4 3 1 1 4 4 4 0 Prp18 domain ParA PF10609.9 EJS43744.1 - 1.1e-92 310.0 0.0 1.3e-92 309.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EJS43744.1 - 2.2e-10 40.7 0.0 4e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EJS43744.1 - 1.1e-06 28.6 0.6 1.6e-05 24.9 0.6 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EJS43744.1 - 8.4e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EJS43744.1 - 9.7e-05 21.7 1.5 0.003 16.8 0.6 2.4 1 1 1 2 2 2 1 Anion-transporting ATPase RsgA_GTPase PF03193.16 EJS43744.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase CBP_BcsQ PF06564.12 EJS43744.1 - 0.026 14.0 0.1 0.052 13.0 0.1 1.6 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 EJS43744.1 - 0.026 14.3 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EJS43744.1 - 0.039 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EJS43744.1 - 0.066 13.0 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ABC_tran PF00005.27 EJS43744.1 - 0.069 13.7 0.1 0.42 11.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_15 PF13175.6 EJS43744.1 - 0.09 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EJS43744.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EJS43744.1 - 0.12 11.5 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 EJS43744.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 EJS43744.1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EJS43744.1 - 0.28 11.6 0.1 0.62 10.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain SNase PF00565.17 EJS43745.1 - 1.6e-27 96.1 0.0 2.7e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MBOAT PF03062.19 EJS43746.1 - 1.7e-82 277.6 28.1 2.9e-82 276.8 28.1 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.25 EJS43747.1 - 2.6e-22 79.5 0.1 7.9e-22 77.9 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43747.1 - 1.1e-11 44.5 0.0 2.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 EJS43747.1 - 0.0002 21.1 1.6 0.00054 19.7 1.6 1.7 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 NOC3p PF07540.11 EJS43747.1 - 0.0069 16.8 2.2 0.059 13.8 0.3 3.0 3 0 0 3 3 3 1 Nucleolar complex-associated protein MINDY_DUB PF04424.13 EJS43748.1 - 2.4e-29 101.7 0.1 4.6e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase FHA PF00498.26 EJS43749.1 - 1.6e-09 38.0 0.0 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF4530 PF15039.6 EJS43749.1 - 0.3 11.3 6.4 0.48 10.6 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) NOA36 PF06524.12 EJS43749.1 - 0.78 9.0 6.0 1.1 8.5 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 EJS43749.1 - 1.3 8.2 4.9 2.4 7.3 4.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4746 PF15928.5 EJS43749.1 - 1.4 8.2 8.3 2.1 7.7 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3682 PF12446.8 EJS43749.1 - 3.7 8.0 9.4 6.7 7.2 9.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) PAC1 PF16094.5 EJS43749.1 - 6 5.9 6.7 9.5 5.3 6.7 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 DEAD PF00270.29 EJS43750.1 - 4.2e-54 183.0 0.0 5.4e-53 179.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS43750.1 - 4.3e-37 126.9 0.2 3.4e-31 107.9 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EJS43750.1 - 7.7e-09 35.8 0.0 7.7e-09 35.8 0.0 2.7 2 1 1 3 3 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EJS43750.1 - 4.6e-05 22.8 0.0 4.6e-05 22.8 0.0 2.5 3 0 0 3 3 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EJS43750.1 - 0.00075 18.9 13.0 0.0027 17.1 0.0 2.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 EJS43750.1 - 0.002 17.8 0.0 0.065 12.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain UTP25 PF06862.12 EJS43750.1 - 0.014 14.2 0.1 0.014 14.2 0.1 3.1 3 1 1 4 4 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 EJS43750.1 - 0.024 15.0 0.0 0.52 10.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EJS43750.1 - 0.24 11.6 1.2 2 8.7 1.2 2.5 1 1 0 1 1 1 0 AAA domain AP3D1 PF06375.11 EJS43750.1 - 2.8 8.2 19.4 5.9 7.1 19.4 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DDRGK PF09756.9 EJS43750.1 - 7.1 6.2 21.4 16 5.0 21.4 1.6 1 0 0 1 1 1 0 DDRGK domain SR-25 PF10500.9 EJS43750.1 - 7.3 6.1 21.4 16 5.1 21.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HSF_DNA-bind PF00447.17 EJS43751.1 - 5.2e-32 110.3 2.5 1.5e-31 108.9 2.5 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding AFT PF08731.11 EJS43752.1 - 1.3e-48 164.0 1.8 1.3e-48 164.0 1.8 2.3 3 0 0 3 3 3 1 Transcription factor AFT DBD_Tnp_Mut PF03108.15 EJS43752.1 - 0.072 13.1 1.4 5.1 7.2 0.7 2.7 2 0 0 2 2 2 0 MuDR family transposase Hanta_G1 PF01567.16 EJS43752.1 - 0.11 11.2 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 RNA_POL_M_15KD PF02150.16 EJS43753.1 - 1.4e-17 63.3 4.4 1.4e-17 63.3 4.4 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 EJS43753.1 - 1.5e-14 53.6 2.3 1.5e-14 53.6 2.3 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-UBP PF02148.19 EJS43753.1 - 0.025 14.9 4.7 0.3 11.5 0.5 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Zn_Tnp_IS1595 PF12760.7 EJS43753.1 - 0.026 14.5 10.6 0.19 11.7 2.6 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF2387 PF09526.10 EJS43753.1 - 0.031 14.4 4.9 1.2 9.3 0.2 2.5 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) DZR PF12773.7 EJS43753.1 - 0.05 13.6 6.9 1.5 8.9 0.4 2.5 2 1 0 2 2 2 0 Double zinc ribbon Lar_restr_allev PF14354.6 EJS43753.1 - 0.14 12.5 0.3 0.14 12.5 0.3 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_10 PF10058.9 EJS43753.1 - 0.28 10.9 7.6 1.3 8.8 0.5 2.5 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Rubredoxin PF00301.20 EJS43753.1 - 0.66 10.1 4.5 35 4.5 0.2 3.3 4 0 0 4 4 4 0 Rubredoxin Nudix_N_2 PF14803.6 EJS43753.1 - 1.2 9.1 10.7 0.89 9.5 1.1 3.2 3 0 0 3 3 3 0 Nudix N-terminal RPA_interact_C PF14768.6 EJS43753.1 - 2.1 9.0 9.0 3.4 8.3 0.8 2.5 2 1 0 2 2 2 0 Replication protein A interacting C-terminal Ribosomal_L12 PF00542.19 EJS43754.1 - 7.7e-24 83.8 13.3 3.5e-23 81.7 10.1 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EJS43754.1 - 2e-12 46.6 11.5 2.5e-11 43.1 7.6 3.1 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 EJS43754.1 - 0.023 15.3 3.2 0.023 15.3 3.2 2.3 1 1 1 2 2 2 0 60s Acidic ribosomal protein NUDIX PF00293.28 EJS43755.1 - 6.3e-15 55.4 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EJS43755.1 - 1.6e-06 27.7 0.1 2.8e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain TGT_C2 PF14810.6 EJS43755.1 - 0.029 14.5 0.0 0.093 12.9 0.0 1.8 2 0 0 2 2 2 0 Patch-forming domain C2 of tRNA-guanine transglycosylase NUDIX-like PF09296.11 EJS43755.1 - 0.044 14.4 0.0 0.075 13.7 0.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain SCA7 PF08313.12 EJS43756.1 - 1.4e-30 105.0 0.8 5.7e-30 103.0 0.8 2.1 1 0 0 1 1 1 1 SCA7, zinc-binding domain zf_C2H2_13 PF18508.1 EJS43756.1 - 3.2e-23 81.1 0.3 6.4e-23 80.1 0.3 1.6 1 0 0 1 1 1 1 Zinc finger domain Glycos_transf_1 PF00534.20 EJS43757.1 - 5.1e-51 172.6 0.0 1.3e-50 171.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EJS43757.1 - 1.5e-15 57.7 0.0 2.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EJS43757.1 - 6.2e-11 42.9 0.0 4.1e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EJS43757.1 - 0.00046 20.7 0.0 0.003 18.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 EJS43757.1 - 0.043 13.9 1.8 13 5.7 0.0 3.1 1 1 1 2 2 2 0 ALG11 mannosyltransferase N-terminus DUF3524 PF12038.8 EJS43757.1 - 0.045 13.6 0.4 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3524) PseudoU_synth_1 PF01416.20 EJS43758.1 - 8.2e-22 77.7 0.0 1.5e-17 64.0 0.1 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase CPSase_L_D2 PF02786.17 EJS43759.1 - 2.5e-85 285.3 0.1 4.7e-85 284.4 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EJS43759.1 - 5.4e-69 231.9 0.0 9.5e-69 231.1 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EJS43759.1 - 7.4e-39 132.7 0.1 1.8e-38 131.5 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EJS43759.1 - 1.7e-30 105.3 0.0 4.5e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EJS43759.1 - 1.1e-27 97.3 0.1 2.4e-27 96.2 0.1 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EJS43759.1 - 2.5e-19 68.9 2.3 2.5e-19 68.9 2.3 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EJS43759.1 - 2.4e-07 30.5 0.0 4.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EJS43759.1 - 6.8e-07 29.0 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EJS43759.1 - 9.3e-06 25.4 5.2 0.019 14.8 0.2 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EJS43759.1 - 3.8e-05 23.8 0.0 0.0001 22.4 0.0 1.8 2 0 0 2 2 1 1 ATP-grasp domain HlyD_D23 PF16576.5 EJS43759.1 - 0.00015 21.1 0.2 0.0064 15.7 0.1 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 EJS43759.1 - 0.0013 18.3 0.0 0.0033 17.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EJS43759.1 - 0.0018 19.0 0.4 0.52 11.0 0.1 3.3 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 EJS43759.1 - 0.011 15.7 1.3 0.13 12.3 0.4 2.8 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.6 EJS43759.1 - 0.014 14.7 0.0 0.038 13.2 0.0 1.7 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp NQRA PF05896.11 EJS43759.1 - 0.055 12.9 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DASH_Duo1 PF08651.10 EJS43760.1 - 2.1e-21 75.5 2.4 2.1e-21 75.5 2.4 2.1 2 0 0 2 2 2 1 DASH complex subunit Duo1 Bac_thur_toxin PF01338.18 EJS43760.1 - 0.049 13.1 1.7 0.069 12.6 1.7 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis toxin Kinetochor_Ybp2 PF08568.10 EJS43761.1 - 1.8e-134 449.6 16.3 2e-134 449.5 16.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin BCDHK_Adom3 PF10436.9 EJS43762.1 - 2.8e-29 102.0 1.8 4.1e-29 101.5 0.9 1.7 1 1 1 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EJS43762.1 - 9.9e-05 22.8 0.0 0.027 15.0 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CBS PF00571.28 EJS43763.1 - 4.7e-20 71.8 2.0 0.00022 21.6 0.0 5.3 5 0 0 5 5 5 5 CBS domain FA_desaturase PF00487.24 EJS43764.1 - 4.3e-18 66.1 19.3 4.3e-18 66.1 19.3 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EJS43764.1 - 7.7e-15 54.8 0.1 2.8e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Cornichon PF03311.14 EJS43765.1 - 4.1e-48 162.7 8.6 4.7e-48 162.5 8.6 1.0 1 0 0 1 1 1 1 Cornichon protein MIF4G PF02854.19 EJS43766.1 - 2.6e-48 164.5 0.1 2.6e-48 164.5 0.1 1.6 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 EJS43766.1 - 1.8e-24 85.7 1.5 7.2e-24 83.8 1.5 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 SUB1_ProdP9 PF18213.1 EJS43766.1 - 0.055 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 AAA PF00004.29 EJS43767.1 - 2.5e-43 147.7 0.0 4.7e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS43767.1 - 3e-14 52.5 0.4 9e-14 51.0 0.0 2.0 3 0 0 3 3 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EJS43767.1 - 3.5e-07 30.1 1.0 8.7e-07 28.8 1.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EJS43767.1 - 6.1e-07 29.7 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EJS43767.1 - 1.7e-06 28.1 0.0 7.3e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EJS43767.1 - 2.4e-05 24.8 0.1 0.00031 21.1 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EJS43767.1 - 2.9e-05 24.4 0.2 0.009 16.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EJS43767.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EJS43767.1 - 0.00097 19.7 0.3 0.021 15.3 0.0 2.8 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EJS43767.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EJS43767.1 - 0.0021 18.2 0.0 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EJS43767.1 - 0.0043 17.3 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EJS43767.1 - 0.0064 16.4 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2072 PF09845.9 EJS43767.1 - 0.0079 16.5 0.8 0.017 15.3 0.8 1.6 1 0 0 1 1 1 1 Zn-ribbon containing protein TIP49 PF06068.13 EJS43767.1 - 0.0091 15.2 0.0 0.028 13.6 0.0 1.8 1 1 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EJS43767.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EJS43767.1 - 0.015 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EJS43767.1 - 0.017 14.6 0.0 0.077 12.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 EJS43767.1 - 0.018 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EJS43767.1 - 0.034 13.9 0.0 0.17 11.6 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EJS43767.1 - 0.039 14.3 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EJS43767.1 - 0.047 13.4 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EJS43767.1 - 0.049 13.2 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EJS43767.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 EJS43767.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 EJS43767.1 - 0.1 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATG16 PF08614.11 EJS43767.1 - 0.13 12.5 1.8 0.22 11.7 1.8 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_30 PF13604.6 EJS43767.1 - 0.15 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EJS43767.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Tropomyosin PF00261.20 EJS43767.1 - 0.18 11.2 2.6 0.26 10.6 0.7 2.0 2 0 0 2 2 2 0 Tropomyosin Glyco_tran_28_C PF04101.16 EJS43768.1 - 2e-33 115.7 0.0 3.9e-33 114.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Arrestin_N PF00339.29 EJS43769.1 - 2e-29 102.6 0.2 4.5e-29 101.4 0.2 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EJS43769.1 - 1.1e-10 42.1 9.1 1e-09 38.9 0.2 3.0 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain RRM_1 PF00076.22 EJS43770.1 - 2.6e-20 72.0 0.0 4.6e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EJS43770.1 - 1.3e-10 40.7 1.0 3.4e-10 39.3 1.0 1.7 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 EJS43770.1 - 0.00033 21.0 0.2 0.00033 21.0 0.2 1.8 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_occluded PF16842.5 EJS43770.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 EJS43770.1 - 0.051 13.7 0.0 0.23 11.6 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif Spt20 PF12090.8 EJS43770.1 - 0.051 13.2 14.5 0.099 12.2 14.5 1.4 1 0 0 1 1 1 0 Spt20 family NDUF_C2 PF06374.11 EJS43770.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Presenilin PF01080.17 EJS43770.1 - 0.18 10.6 2.7 0.2 10.4 2.7 1.2 1 0 0 1 1 1 0 Presenilin NST1 PF13945.6 EJS43770.1 - 0.36 10.9 18.4 0.65 10.1 18.4 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Menin PF05053.13 EJS43770.1 - 0.46 8.8 12.0 0.61 8.4 12.0 1.2 1 0 0 1 1 1 0 Menin TCP PF03634.13 EJS43770.1 - 3.6 8.1 11.4 2.4 8.7 8.1 2.0 2 0 0 2 2 2 0 TCP family transcription factor DUF4834 PF16118.5 EJS43770.1 - 5.7 8.0 9.8 12 6.9 9.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIS_M PF07500.14 EJS43771.1 - 5e-24 84.9 0.4 5e-24 84.9 0.4 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EJS43771.1 - 3.2e-17 62.1 6.4 3.2e-17 62.1 6.4 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EJS43771.1 - 1.9e-10 40.6 0.9 5.2e-10 39.2 0.9 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF4484 PF14831.6 EJS43771.1 - 0.0032 17.5 1.0 0.0045 17.0 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) PIN_4 PF13638.6 EJS43771.1 - 1.5 9.1 6.1 1.2 9.4 3.6 2.2 2 1 0 2 2 2 0 PIN domain ACR_tran PF00873.19 EJS43771.1 - 5.3 4.6 5.0 7.3 4.1 2.1 1.9 1 1 1 2 2 2 0 AcrB/AcrD/AcrF family ALAD PF00490.21 EJS43772.1 - 1.2e-118 396.0 0.0 1.4e-118 395.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase ANAPC4_WD40 PF12894.7 EJS43774.1 - 5e-13 49.2 3.7 0.00021 21.5 0.1 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJS43774.1 - 9.2e-12 45.3 21.8 0.00036 21.3 0.2 6.2 8 0 0 8 8 8 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EJS43774.1 - 1.1e-06 27.9 0.3 9.7e-05 21.5 0.0 3.3 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2790 PF10976.8 EJS43774.1 - 0.12 12.4 0.5 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2790) CBS PF00571.28 EJS43775.1 - 1.4e-25 89.5 4.9 1.3e-11 44.8 0.2 4.3 4 0 0 4 4 4 4 CBS domain OPT PF03169.15 EJS43776.1 - 1.5e-176 588.6 17.8 1.8e-176 588.5 17.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1189 PF06691.11 EJS43776.1 - 0.79 9.2 7.5 0.43 10.1 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) DUF5423 PF17461.2 EJS43776.1 - 0.98 8.2 2.8 0.82 8.5 1.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5423) SLD3 PF08639.10 EJS43777.1 - 1.4e-54 185.8 20.8 2.1e-37 129.1 13.0 2.2 1 1 1 2 2 2 2 DNA replication regulator SLD3 Sld3_N PF18523.1 EJS43777.1 - 1.3e-37 128.5 1.1 5e-37 126.6 1.1 2.1 1 0 0 1 1 1 1 Sld3 N-terminal domain TAF PF02969.17 EJS43778.1 - 5.4e-30 103.4 0.2 1.4e-29 102.1 0.2 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 EJS43778.1 - 1.2e-28 99.2 0.0 3.3e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 EJS43778.1 - 0.00036 20.9 1.3 0.024 15.0 0.1 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.14 EJS43778.1 - 0.0073 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TFIID-31kDa PF02291.15 EJS43778.1 - 0.0088 16.1 0.3 0.024 14.7 0.3 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 EJS43778.1 - 0.012 15.9 1.9 1.2 9.5 0.1 3.3 3 0 0 3 3 3 0 CENP-S protein DUF348 PF03990.14 EJS43778.1 - 0.035 13.9 0.0 0.095 12.5 0.0 1.7 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain CBFD_NFYB_HMF PF00808.23 EJS43778.1 - 0.18 12.1 0.3 0.74 10.1 0.1 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CDC27 PF09507.10 EJS43779.1 - 9.9 5.4 29.2 11 5.2 29.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EF-hand_7 PF13499.6 EJS43780.1 - 1.8e-12 47.5 2.8 8.4e-09 35.8 0.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EJS43780.1 - 4.5e-09 36.0 1.5 4.2e-07 29.7 0.3 3.0 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 EJS43780.1 - 6.6e-09 35.0 4.8 0.00083 19.1 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EJS43780.1 - 1.3e-08 33.7 5.9 0.0012 18.3 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EJS43780.1 - 2.1e-08 34.4 0.1 0.0025 18.1 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 EJS43780.1 - 0.0029 17.9 0.2 0.27 11.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 EJS43780.1 - 0.01 16.7 0.0 0.019 15.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain IreB PF06135.12 EJS43780.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 IreB regulatory phosphoprotein tRNA_bind PF01588.20 EJS43781.1 - 6.5e-28 96.7 0.0 1.1e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GP4 PF03010.14 EJS43781.1 - 0.039 13.9 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 GP4 NARP1 PF12569.8 EJS43781.1 - 0.052 12.5 9.9 0.072 12.0 9.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Viral_protease PF08715.10 EJS43781.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Papain like viral protease RR_TM4-6 PF06459.12 EJS43781.1 - 0.9 9.3 6.1 1.5 8.6 6.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HD_3 PF13023.6 EJS43782.1 - 2.1e-36 125.4 0.2 2.6e-36 125.0 0.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EJS43782.1 - 3e-10 40.2 0.1 3.9e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EJS43782.1 - 5.5e-06 26.6 0.0 9.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 HD domain WD40 PF00400.32 EJS43783.1 - 1.5e-20 73.1 13.1 8.1e-05 23.3 0.6 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS43783.1 - 5.5e-12 45.8 0.6 0.0092 16.3 0.1 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain MMR_HSR1 PF01926.23 EJS43784.1 - 4.8e-16 58.8 0.2 1.3e-14 54.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJS43784.1 - 1.8e-07 30.8 0.1 6.7e-06 25.7 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EJS43784.1 - 7.7e-06 25.9 0.1 0.007 16.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EJS43784.1 - 0.003 16.9 0.1 0.0064 15.9 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EJS43784.1 - 0.75 9.8 5.4 0.17 11.9 0.9 2.4 3 1 0 3 3 3 0 Dynamin family WAC_Acf1_DNA_bd PF10537.9 EJS43785.1 - 9.6e-35 119.2 0.5 3.3e-34 117.4 0.5 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EJS43785.1 - 8.4e-12 45.4 2.4 2.5e-11 43.9 0.0 3.1 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EJS43785.1 - 6.8e-11 42.3 0.1 6.9e-10 39.1 0.0 2.4 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 EJS43785.1 - 0.0012 18.4 0.0 0.0031 17.0 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 mRNA_cap_enzyme PF01331.19 EJS43786.1 - 1.7e-69 233.6 0.0 6.7e-69 231.6 0.0 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EJS43786.1 - 1.1e-32 112.8 0.4 1.9e-32 112.1 0.4 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EJS43786.1 - 2.9e-07 30.4 0.0 9e-05 22.2 0.0 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DUF4420 PF14390.6 EJS43786.1 - 0.05 12.8 0.4 0.094 11.9 0.1 1.5 2 0 0 2 2 2 0 Putative PD-(D/E)XK family member, (DUF4420) DnaJ PF00226.31 EJS43787.1 - 4.9e-19 68.2 0.9 1.1e-18 67.1 0.9 1.7 1 0 0 1 1 1 1 DnaJ domain Scs3p PF10261.9 EJS43788.1 - 4e-68 229.6 8.8 4.8e-68 229.3 8.8 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM MTHFR PF02219.17 EJS43789.1 - 8.2e-125 415.9 0.0 1.2e-124 415.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Mon1 PF03164.14 EJS43790.1 - 1.5e-142 475.5 7.7 1.8e-142 475.2 7.7 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Ribosomal_S5 PF00333.20 EJS43791.1 - 1.5e-26 92.2 3.6 6.2e-26 90.2 2.1 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EJS43791.1 - 2.2e-23 81.5 0.0 3.7e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Nab2 PF11517.8 EJS43792.1 - 5.5e-49 164.7 2.9 8.4e-49 164.1 2.9 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.6 EJS43792.1 - 1.2e-19 70.0 74.6 3.8e-05 24.0 3.8 7.3 7 0 0 7 7 7 5 RNA-binding, Nab2-type zinc finger Nab2p_Zf1 PF18260.1 EJS43792.1 - 8.5e-17 60.7 8.6 8.5e-17 60.7 8.6 3.4 3 0 0 3 3 3 1 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 DUF2722 PF10846.8 EJS43792.1 - 0.00024 20.2 5.5 0.00037 19.6 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 EJS43792.1 - 0.012 15.7 18.8 0.019 15.0 18.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EJS43792.1 - 0.021 15.5 14.3 0.054 14.1 14.3 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roughex PF06020.11 EJS43792.1 - 0.092 11.8 8.2 0.14 11.3 8.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF2391 PF09622.10 EJS43792.1 - 0.092 12.1 1.2 0.13 11.6 1.2 1.1 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) SHOCT PF09851.9 EJS43792.1 - 0.14 11.9 1.0 0.37 10.6 1.0 1.8 1 0 0 1 1 1 0 Short C-terminal domain DUF4834 PF16118.5 EJS43792.1 - 0.32 12.0 2.1 0.73 10.8 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF775 PF05603.12 EJS43792.1 - 0.57 9.7 7.3 0.66 9.5 5.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Het-C PF07217.11 EJS43792.1 - 0.6 8.6 6.2 0.88 8.0 6.2 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF4175 PF13779.6 EJS43792.1 - 1.1 7.1 17.4 1.7 6.5 17.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.17 EJS43792.1 - 2.8 6.6 4.3 4.1 6.1 4.3 1.2 1 0 0 1 1 1 0 Presenilin PKI PF02827.16 EJS43792.1 - 3.2 8.0 7.3 6.8 7.0 7.3 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor EIIBC-GUT_N PF03612.14 EJS43792.1 - 3.5 7.3 6.7 12 5.6 4.7 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Spt20 PF12090.8 EJS43792.1 - 4.9 6.7 22.6 8.1 6.0 22.6 1.3 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 EJS43792.1 - 7.8 6.5 6.1 4.8 7.2 1.9 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FoP_duplication PF13865.6 EJS43792.1 - 8.1 7.1 15.3 4.8 7.8 7.4 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 HA2 PF04408.23 EJS43794.1 - 1.2e-22 80.2 0.0 3.1e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EJS43794.1 - 1.7e-22 79.5 0.0 6.7e-22 77.7 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EJS43794.1 - 7.5e-12 45.6 0.0 2.2e-11 44.1 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJS43794.1 - 6.1e-10 39.1 0.1 1.2e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EJS43794.1 - 1.2e-06 28.8 0.0 4.1e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EJS43794.1 - 0.00017 21.3 0.1 0.00046 19.9 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EJS43794.1 - 0.00041 20.7 0.1 0.00076 19.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJS43794.1 - 0.00084 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EJS43794.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_23 PF13476.6 EJS43794.1 - 0.0025 18.4 0.1 0.016 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EJS43794.1 - 0.0044 17.0 0.2 0.4 10.7 0.2 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EJS43794.1 - 0.023 14.2 0.0 0.08 12.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 EJS43794.1 - 0.056 12.7 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 EJS43794.1 - 0.064 13.0 0.1 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 EJS43794.1 - 0.067 12.2 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein EMP24_GP25L PF01105.24 EJS43795.1 - 2e-44 151.7 0.1 2.3e-44 151.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Lsr2 PF11774.8 EJS43795.1 - 0.0081 16.3 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 1 Lsr2 Yip1 PF04893.17 EJS43796.1 - 3.8e-13 49.5 10.3 5.1e-13 49.1 10.3 1.2 1 0 0 1 1 1 1 Yip1 domain Kelch_4 PF13418.6 EJS43797.1 - 1.3e-14 53.9 4.7 1.4e-05 25.0 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EJS43797.1 - 1.8e-14 53.4 2.9 5.7e-08 32.8 0.0 4.9 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 EJS43797.1 - 2.3e-13 49.5 0.3 0.00017 21.1 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EJS43797.1 - 1e-08 34.8 0.9 1.2e-05 25.1 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 EJS43797.1 - 5.9e-08 32.8 0.8 0.00081 19.6 0.0 5.5 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.6 EJS43797.1 - 4.8e-05 23.2 0.0 0.026 14.5 0.0 3.7 4 0 0 4 4 4 1 Kelch motif UpxZ PF06603.11 EJS43797.1 - 0.15 12.4 1.6 0.41 11.0 1.6 1.7 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists NID PF07292.13 EJS43797.1 - 0.18 12.4 0.4 19 6.0 0.2 2.7 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) D-ser_dehydrat PF14031.6 EJS43798.1 - 2.5e-18 66.5 0.0 4.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EJS43798.1 - 7.9e-11 42.0 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HEAT_EZ PF13513.6 EJS43799.1 - 7.2e-29 99.8 13.5 0.00011 22.6 0.0 15.6 14 4 3 17 17 17 6 HEAT-like repeat HEAT PF02985.22 EJS43799.1 - 1.8e-28 96.2 21.0 0.004 17.3 0.0 18.6 23 0 0 23 23 20 6 HEAT repeat Gcn1_N PF12074.8 EJS43799.1 - 4.1e-26 92.1 0.4 3e-11 43.2 0.0 4.4 3 0 0 3 3 3 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_2 PF13646.6 EJS43799.1 - 2.2e-22 79.2 20.2 0.00015 22.1 0.2 12.4 6 2 6 12 12 12 5 HEAT repeats CLASP_N PF12348.8 EJS43799.1 - 1.3e-14 54.4 8.8 0.0011 18.6 0.0 9.6 10 1 0 11 11 11 2 CLASP N terminal Cnd1 PF12717.7 EJS43799.1 - 4.3e-14 52.9 24.0 0.088 12.8 0.0 13.1 10 3 4 14 14 14 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EJS43799.1 - 4.7e-10 39.9 9.4 0.075 13.6 0.0 10.0 9 2 2 12 12 12 2 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EJS43799.1 - 7.2e-05 22.0 11.7 3.3 6.7 0.1 7.1 8 0 0 8 8 8 3 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 EJS43799.1 - 0.0077 16.1 17.8 66 3.4 0.0 10.5 8 2 3 11 11 11 0 Domain of unknown function (DUF3385) Nipped-B_C PF12830.7 EJS43799.1 - 0.032 14.2 0.5 16 5.3 0.0 4.4 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EJS43799.1 - 0.34 11.2 4.9 24 5.3 0.2 6.0 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 EJS43799.1 - 1.5 9.0 12.2 30 4.8 0.1 7.8 10 0 0 10 10 9 0 Required for nuclear transport of RNA pol II C-terminus 1 Hist_deacetyl PF00850.19 EJS43801.1 - 1.7e-84 283.9 0.0 2.1e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MT-A70 PF05063.14 EJS43802.1 - 3.7e-58 196.2 0.2 7e-58 195.3 0.2 1.5 1 0 0 1 1 1 1 MT-A70 Blt1_C PF17183.4 EJS43802.1 - 0.09 12.4 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Get5 carboxyl domain COX6A PF02046.15 EJS43803.1 - 2.8e-37 127.6 0.2 3.2e-37 127.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa WD40 PF00400.32 EJS43804.1 - 8e-15 55.0 1.3 0.0042 17.9 0.0 7.1 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS43804.1 - 9.5e-05 22.6 0.1 20 5.5 0.0 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S26e PF01283.19 EJS43805.1 - 3e-51 172.4 9.8 3.5e-51 172.2 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e COX5B PF01215.19 EJS43806.1 - 7.2e-65 216.5 0.0 8.5e-65 216.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb 2-Hacid_dh_C PF02826.19 EJS43807.1 - 1.4e-31 109.2 0.0 2.1e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EJS43807.1 - 1.7e-05 24.5 0.0 0.0011 18.6 0.0 2.6 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EJS43807.1 - 0.00028 21.1 0.0 0.00049 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EJS43807.1 - 0.012 15.3 0.1 0.031 13.9 0.1 1.8 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Cys_Met_Meta_PP PF01053.20 EJS43808.1 - 3.6e-129 430.6 0.0 4.2e-129 430.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme BpuJI_N PF11564.8 EJS43808.1 - 0.033 13.4 0.1 0.06 12.5 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal Met_gamma_lyase PF06838.11 EJS43808.1 - 0.12 10.9 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase DUF3543 PF12063.8 EJS43809.1 - 6.7e-85 284.5 7.1 1.2e-84 283.7 7.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EJS43809.1 - 9.6e-60 202.2 0.0 2e-59 201.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43809.1 - 3.9e-45 154.2 0.0 7.6e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43809.1 - 0.029 13.7 0.0 0.66 9.2 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 EJS43810.1 - 1.7e-60 204.7 0.0 2.2e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43810.1 - 3.5e-31 108.4 0.0 5.5e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43810.1 - 1.5e-07 31.1 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EJS43810.1 - 3e-06 26.3 0.0 4.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EJS43810.1 - 0.0077 15.3 0.1 0.02 13.9 0.0 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 Bud13 PF09736.9 EJS43812.1 - 2.5e-21 76.6 12.2 3.4e-20 72.9 4.0 3.1 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Nucleoporin_FG PF13634.6 EJS43813.1 - 4e-20 72.5 113.1 6.2e-09 36.6 22.8 4.8 2 1 3 5 5 5 4 Nucleoporin FG repeat region DUF1664 PF07889.12 EJS43813.1 - 0.0025 17.8 1.5 0.22 11.5 0.6 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) FAM117 PF15388.6 EJS43813.1 - 0.032 13.7 0.4 0.056 12.9 0.4 1.4 1 0 0 1 1 1 0 Protein Family FAM117 Fibin PF15819.5 EJS43813.1 - 0.12 12.1 6.9 0.098 12.4 0.6 2.6 2 1 1 3 3 3 0 Fin bud initiation factor homologue Lzipper-MIP1 PF14389.6 EJS43813.1 - 1.8 8.9 8.6 1.9 8.8 1.1 2.7 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Sua5_yciO_yrdC PF01300.18 EJS43815.1 - 6.4e-47 159.3 0.0 1.1e-46 158.6 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EJS43815.1 - 2.5e-31 109.0 0.0 3.7e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF928 PF06051.12 EJS43815.1 - 0.095 12.5 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) E1-E2_ATPase PF00122.20 EJS43816.1 - 1.5e-48 164.7 0.2 1.5e-48 164.7 0.2 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EJS43816.1 - 6.6e-47 159.6 1.3 6.6e-47 159.6 1.3 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EJS43816.1 - 7.4e-21 75.4 0.1 4e-20 73.0 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJS43816.1 - 3e-17 62.5 0.1 6.6e-17 61.4 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EJS43816.1 - 6.5e-16 57.8 0.0 1.7e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJS43816.1 - 8.8e-05 22.4 0.3 0.0062 16.3 0.3 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 EJS43816.1 - 0.03 14.5 3.8 1 9.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Copper-fist PF00649.18 EJS43817.1 - 3.2e-20 71.3 2.1 3.2e-20 71.3 2.1 1.9 1 1 1 2 2 2 1 Copper fist DNA binding domain SNF2_N PF00176.23 EJS43818.1 - 1.4e-57 195.0 0.0 2.2e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EJS43818.1 - 1.9e-49 168.3 5.2 4.8e-49 167.0 5.2 1.7 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 EJS43818.1 - 2.3e-16 60.1 0.0 5.4e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS43818.1 - 2e-08 34.5 0.0 5.4e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EJS43818.1 - 2.1e-05 23.8 0.1 2.1e-05 23.8 0.1 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Yip1 PF04893.17 EJS43819.1 - 1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Yip1 domain DUF2427 PF10348.9 EJS43819.1 - 8.1e-05 22.4 0.9 0.00022 21.0 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) OCD_Mu_crystall PF02423.15 EJS43820.1 - 2e-07 30.2 0.0 0.009 15.0 0.0 2.2 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Glyco_hydro_38N PF01074.22 EJS43821.1 - 1.3e-83 280.7 0.3 2e-83 280.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EJS43821.1 - 5e-57 193.4 0.3 1.2e-56 192.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EJS43821.1 - 1.4e-27 95.7 0.0 2.9e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EJS43821.1 - 2.8e-08 33.7 0.1 9.7e-08 32.0 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Med5 PF08689.10 EJS43822.1 - 0 1499.4 60.1 0 1499.2 60.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DUF3272 PF11676.8 EJS43822.1 - 0.02 15.1 0.1 6.7 7.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) SNF2_N PF00176.23 EJS43823.1 - 1.7e-66 224.3 2.2 1.7e-66 224.3 2.2 2.2 1 1 1 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 EJS43823.1 - 7.3e-48 162.3 24.5 7.3e-48 162.3 24.5 4.2 3 1 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 EJS43823.1 - 2.9e-18 66.2 0.0 1.9e-17 63.6 0.0 2.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJS43823.1 - 0.00018 21.4 0.0 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Chorismate_synt PF01264.21 EJS43824.1 - 2.3e-139 463.7 0.0 2.6e-139 463.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ribosomal_L6 PF00347.23 EJS43825.1 - 2e-31 108.5 11.4 9e-17 61.5 5.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF2096 PF09869.9 EJS43825.1 - 0.0059 16.7 0.3 0.009 16.1 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2096) UAF_Rrn10 PF05234.11 EJS43825.1 - 0.096 12.9 0.2 0.21 11.8 0.2 1.6 1 0 0 1 1 1 0 UAF complex subunit Rrn10 PCRF PF03462.18 EJS43826.1 - 1.4e-50 171.8 1.2 3e-50 170.8 0.0 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EJS43826.1 - 8.6e-39 132.1 3.9 1.8e-38 131.0 3.9 1.5 1 0 0 1 1 1 1 RF-1 domain Dynamin_N PF00350.23 EJS43826.1 - 0.033 14.3 0.1 0.073 13.1 0.1 1.6 1 0 0 1 1 1 0 Dynamin family DUF2543 PF10820.8 EJS43826.1 - 1.2 9.4 4.2 0.51 10.5 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2543) HECT PF00632.25 EJS43827.1 - 8.1e-88 294.8 0.2 1.5e-87 294.0 0.2 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ArAE_2_N PF10337.9 EJS43828.1 - 9.1e-106 354.7 2.2 9.1e-106 354.7 2.2 2.5 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EJS43828.1 - 1.8e-14 54.0 13.9 1.8e-14 54.0 13.9 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 EJS43828.1 - 1.7e-07 30.4 5.9 9.3e-06 24.7 2.8 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 EJS43828.1 - 0.0008 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 H2TH PF06831.14 EJS43828.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain ArAE_1 PF06081.11 EJS43828.1 - 1.2 9.3 7.6 0.47 10.6 2.2 2.7 2 1 0 2 2 2 0 Aromatic acid exporter family member 1 TRP PF06011.12 EJS43829.1 - 9.1e-155 515.6 43.6 1.2e-154 515.2 43.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EJS43829.1 - 6.3e-41 140.0 1.0 1.1e-40 139.2 1.0 1.4 1 0 0 1 1 1 1 ML-like domain Aminotran_1_2 PF00155.21 EJS43830.1 - 3.4e-20 72.6 0.0 4.5e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EJS43830.1 - 0.17 11.1 0.1 0.76 9.0 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EJS43830.1 - 0.23 10.7 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase MCM PF00493.23 EJS43831.1 - 2.7e-103 343.9 0.4 4.2e-103 343.2 0.4 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EJS43831.1 - 8.8e-40 135.5 0.1 3.6e-39 133.5 0.0 2.0 2 0 0 2 2 2 1 MCM OB domain MCM6_C PF18263.1 EJS43831.1 - 3.4e-31 107.7 3.5 8.8e-31 106.3 3.5 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EJS43831.1 - 3.6e-26 91.4 2.2 3.6e-26 91.4 2.2 1.9 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 EJS43831.1 - 6.5e-26 90.9 0.1 2.4e-25 89.1 0.1 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EJS43831.1 - 2.9e-07 30.1 0.0 8.3e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EJS43831.1 - 0.0037 17.0 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EJS43831.1 - 0.0085 16.0 0.1 0.031 14.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2004 PF09406.10 EJS43831.1 - 0.057 13.8 0.6 0.22 11.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) AAA_5 PF07728.14 EJS43831.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GIDA_assoc PF13932.6 EJS43831.1 - 0.076 13.2 2.2 0.11 12.7 0.3 2.2 2 0 0 2 2 2 0 GidA associated domain NAM-associated PF14303.6 EJS43831.1 - 0.13 13.0 0.2 0.13 13.0 0.2 2.5 3 0 0 3 3 1 0 No apical meristem-associated C-terminal domain EamA PF00892.20 EJS43832.1 - 1.4e-08 35.0 32.2 0.00016 21.8 10.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family HAD_2 PF13419.6 EJS43833.1 - 3.2e-08 33.9 0.0 5.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJS43833.1 - 1.1e-06 29.1 0.0 7.1e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EJS43833.1 - 0.011 15.5 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 Acid Phosphatase NIF3 PF01784.18 EJS43834.1 - 7.5e-67 225.5 0.2 9e-67 225.3 0.2 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) tRNA-synt_1c_C PF03950.18 EJS43835.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Kinesin PF00225.23 EJS43836.1 - 6.5e-114 380.3 1.0 6.5e-114 380.3 1.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EJS43836.1 - 1.5e-26 93.2 2.3 1.9e-26 92.8 0.1 2.4 2 1 0 2 2 2 1 Microtubule binding AAA_33 PF13671.6 EJS43836.1 - 0.091 12.9 0.0 8 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Cyclin PF08613.11 EJS43837.1 - 0.00047 20.6 0.1 0.00047 20.6 0.1 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EJS43837.1 - 0.061 13.1 0.0 0.061 13.1 0.0 2.4 2 1 0 2 2 2 0 Cyclin, N-terminal domain TFIIA PF03153.13 EJS43837.1 - 0.16 11.9 19.6 0.011 15.8 12.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 EJS43838.1 - 3.6e-12 46.6 16.8 3.9e-06 27.5 1.5 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS43838.1 - 5.2e-09 36.3 0.0 0.003 17.8 0.0 3.0 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EJS43838.1 - 0.0059 15.6 0.1 0.71 8.8 0.0 3.4 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EJS43838.1 - 0.1 12.6 0.0 6.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 EJS43838.1 - 0.1 12.4 0.0 2.4 8.0 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF2415 PF10313.9 EJS43838.1 - 0.19 11.7 0.6 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) ATP_bind_3 PF01171.20 EJS43839.1 - 3.1e-17 62.9 0.0 5.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 EJS43839.1 - 1.5e-15 56.4 5.2 1.5e-15 56.4 5.2 3.2 3 1 1 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 EJS43839.1 - 0.0082 15.0 0.0 0.015 14.1 0.0 1.4 1 1 0 1 1 1 1 tRNA methyl transferase CTU2 PF10288.9 EJS43839.1 - 0.095 12.9 0.3 0.095 12.9 0.3 2.7 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 PAPS_reduct PF01507.19 EJS43839.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family zf-ribbon_3 PF13248.6 EJS43839.1 - 5.1 6.6 9.0 13 5.3 3.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Ras PF00071.22 EJS43840.1 - 1.2e-59 200.5 0.3 1.5e-59 200.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS43840.1 - 1.3e-34 119.0 0.1 1.9e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS43840.1 - 4.1e-13 49.2 0.0 5.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EJS43840.1 - 5e-07 29.8 0.1 7.9e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJS43840.1 - 6.2e-05 22.6 0.2 0.00016 21.3 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.14 EJS43840.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Gtr1_RagA PF04670.12 EJS43840.1 - 0.0013 18.1 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EJS43840.1 - 0.0014 18.5 0.0 0.0091 15.9 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EJS43840.1 - 0.0025 17.3 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EJS43840.1 - 0.018 15.4 0.0 0.027 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 EJS43840.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 EJS43840.1 - 0.033 14.5 0.0 0.086 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EJS43840.1 - 0.037 14.5 0.3 0.061 13.8 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EJS43840.1 - 0.048 13.4 0.1 0.088 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EJS43840.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.9 EJS43840.1 - 0.086 12.6 0.0 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EJS43840.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AMPK1_CBM PF16561.5 EJS43841.1 - 9.6e-30 102.6 0.1 1.8e-29 101.8 0.1 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EJS43841.1 - 3.2e-27 94.6 3.2 3.2e-27 94.6 3.2 2.1 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Bact_transglu_N PF08379.10 EJS43841.1 - 0.078 13.9 0.0 0.38 11.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial transglutaminase-like N-terminal region SPT16 PF08644.11 EJS43842.1 - 5.9e-49 166.1 0.2 5.9e-49 166.1 0.2 2.4 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EJS43842.1 - 1.8e-48 164.4 0.1 1.8e-48 164.4 0.1 3.3 4 0 0 4 4 4 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EJS43842.1 - 1.7e-29 103.1 0.0 3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EJS43842.1 - 2.9e-13 50.0 0.4 1.8e-12 47.5 0.1 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Clathrin PF00637.20 EJS43843.1 - 3.4e-195 639.8 58.1 1.6e-33 115.6 0.2 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EJS43843.1 - 1.9e-26 91.7 1.0 7.7e-26 89.8 0.3 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 EJS43843.1 - 1.2e-25 88.5 5.1 4e-06 26.9 0.3 5.7 5 0 0 5 5 5 5 Clathrin propeller repeat Clathrin-link PF09268.10 EJS43843.1 - 1.5e-08 33.8 0.5 1.5e-08 33.8 0.5 3.2 3 0 0 3 3 3 1 Clathrin, heavy-chain linker TPR_7 PF13176.6 EJS43843.1 - 0.0025 17.7 6.0 17 5.8 0.0 6.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJS43843.1 - 0.063 13.5 5.8 0.47 10.8 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EJS43843.1 - 1 9.7 7.0 1.5 9.2 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ACOX PF01756.19 EJS43844.1 - 2e-42 144.8 0.0 4e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EJS43844.1 - 3e-22 78.6 0.0 5.5e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EJS43844.1 - 5.8e-11 43.0 0.0 2.5e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EJS43844.1 - 0.00066 19.9 0.0 0.011 15.9 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_S10 PF00450.22 EJS43845.1 - 4.6e-111 372.2 0.4 7.1e-111 371.6 0.4 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase BUD22 PF09073.10 EJS43845.1 - 0.031 13.6 40.3 0.062 12.6 40.3 1.4 1 0 0 1 1 1 0 BUD22 SLC12 PF03522.15 EJS43845.1 - 0.3 10.1 12.4 0.56 9.2 12.4 1.4 1 0 0 1 1 1 0 Solute carrier family 12 FeoB_associated PF12669.7 EJS43845.1 - 0.85 10.1 3.2 0.76 10.2 1.4 1.9 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein EphA2_TM PF14575.6 EJS43845.1 - 3.8 8.5 0.0 3.8 8.5 0.0 3.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ORC6 PF05460.13 EJS43845.1 - 6 6.0 11.5 12 5.0 11.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Zip PF02535.22 EJS43846.1 - 2.8e-65 220.7 1.7 3.2e-65 220.6 1.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Hexokinase_2 PF03727.16 EJS43847.1 - 7.1e-77 258.1 0.0 9.8e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EJS43847.1 - 1e-69 234.5 0.0 1.4e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 EJS43847.1 - 0.0043 16.7 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Ppx-GppA PF02541.16 EJS43848.1 - 2.3e-95 319.3 0.0 3e-95 318.9 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family PDEase_II PF02112.15 EJS43849.1 - 1e-115 386.5 0.0 1.2e-115 386.3 0.0 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EJS43849.1 - 0.00069 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EJS43849.1 - 0.16 12.0 1.3 0.33 10.9 1.3 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Herpes_ICP4_N PF03584.15 EJS43849.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.5 1 1 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Brr6_like_C_C PF10104.9 EJS43850.1 - 3.2e-43 146.7 2.0 3.9e-43 146.4 2.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain tRNA-synt_1c PF00749.21 EJS43851.1 - 3.9e-122 407.1 0.1 5.2e-122 406.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EJS43851.1 - 1.1e-38 132.8 0.9 2.9e-38 131.4 0.9 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 EJS43851.1 - 4e-09 36.7 1.7 1.2e-08 35.2 1.7 1.9 1 0 0 1 1 1 1 Glutamate--tRNA ligase N-terminal domain GST_C PF00043.25 EJS43851.1 - 0.14 12.4 0.0 0.45 10.8 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Plus-3 PF03126.18 EJS43852.1 - 1.9e-30 105.6 0.5 5.2e-30 104.2 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain Ank PF00023.30 EJS43853.1 - 9.9e-09 35.3 0.0 0.0052 17.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EJS43853.1 - 1.6e-07 31.1 0.0 0.0016 18.8 0.0 3.5 3 2 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EJS43853.1 - 2.9e-07 31.0 0.0 6.7e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EJS43853.1 - 3.1e-06 27.3 0.3 0.0083 16.4 0.0 4.0 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EJS43853.1 - 0.00019 21.9 0.9 0.037 14.6 0.1 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) IBN_N PF03810.19 EJS43854.1 - 9.5e-09 35.1 4.4 1.9e-08 34.1 0.1 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain DUF592 PF04574.13 EJS43854.1 - 0.33 10.7 4.6 0.14 11.9 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF592) EF-hand_14 PF17959.1 EJS43854.1 - 0.76 10.2 5.5 2.5 8.5 0.1 4.1 4 0 0 4 4 4 0 EF-hand domain ANAPC10 PF03256.16 EJS43855.1 - 1.5e-37 129.1 0.0 1.9e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Cse1 PF08506.10 EJS43856.1 - 6.9e-175 581.2 14.3 1e-174 580.7 13.0 1.9 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 EJS43856.1 - 2.5e-108 362.4 11.1 2.5e-108 362.4 11.1 2.0 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EJS43856.1 - 1.1e-18 66.9 1.3 3.6e-17 62.0 0.0 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EJS43856.1 - 0.0022 18.1 0.3 0.025 14.6 0.0 3.1 2 1 0 2 2 2 1 Exportin 1-like protein CBFB_NFYA PF02045.15 EJS43857.1 - 4.1e-27 94.6 9.0 4.1e-27 94.6 9.0 2.0 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 EJS43857.1 - 0.96 9.4 18.7 1.3 9.0 18.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GIDA PF01134.22 EJS43858.1 - 1.4e-157 524.8 0.0 1.9e-157 524.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EJS43858.1 - 1.7e-66 224.4 0.0 2.5e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 EJS43858.1 - 6.4e-08 32.2 1.2 6.4e-07 28.9 1.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EJS43858.1 - 5.1e-06 26.1 0.6 8.5e-06 25.4 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EJS43858.1 - 0.00037 19.7 0.2 0.0016 17.6 0.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EJS43858.1 - 0.00096 18.3 1.8 0.0046 16.1 1.0 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EJS43858.1 - 0.0022 17.3 0.4 0.0067 15.7 0.3 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EJS43858.1 - 0.0025 17.1 0.1 0.0094 15.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJS43858.1 - 0.0038 17.8 0.1 0.011 16.3 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJS43858.1 - 0.0044 17.0 0.1 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EJS43858.1 - 0.06 12.6 0.3 0.095 11.9 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EJS43858.1 - 0.067 12.8 0.3 5.7 6.4 0.4 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EJS43858.1 - 0.14 12.6 0.1 1.7 9.1 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EJS43858.1 - 0.16 12.2 1.3 0.45 10.8 1.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EJS43858.1 - 0.29 9.8 5.5 0.23 10.1 1.3 2.5 3 0 0 3 3 3 0 HI0933-like protein GARS_A PF01071.19 EJS43859.1 - 1.4e-81 273.0 0.0 2.2e-81 272.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EJS43859.1 - 4.6e-33 114.6 0.0 1e-32 113.5 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EJS43859.1 - 2.5e-31 108.3 0.0 1.3e-30 106.0 0.0 2.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EJS43859.1 - 3.4e-27 94.5 0.3 7.8e-27 93.4 0.3 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EJS43859.1 - 2.6e-16 60.0 1.2 1e-15 58.1 1.2 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_2 PF08442.10 EJS43859.1 - 0.022 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_3 PF02655.14 EJS43859.1 - 0.027 14.5 0.2 0.084 12.9 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp PF02222.22 EJS43859.1 - 0.081 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Sec15 PF04091.12 EJS43860.1 - 8.3e-105 350.7 5.8 8.3e-105 350.7 5.8 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like ApoO PF09769.9 EJS43862.1 - 1.2 9.1 3.8 3.1 7.8 0.3 3.1 4 0 0 4 4 4 0 Apolipoprotein O SPRY PF00622.28 EJS43863.1 - 4.7e-37 126.8 0.2 9e-37 125.9 0.2 1.5 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 EJS43863.1 - 2.9e-12 46.7 2.7 6.2e-12 45.6 2.7 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EJS43863.1 - 0.0025 17.7 0.1 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 LisH Ribosomal_L29e PF01779.17 EJS43864.1 - 6.8e-24 83.9 9.4 8.9e-24 83.5 9.4 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family UCR_hinge PF02320.16 EJS43865.1 - 9.1e-22 77.0 3.2 9.1e-22 77.0 3.2 1.6 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.13 EJS43865.1 - 4.3e-05 23.5 15.1 4.7e-05 23.4 15.1 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region Nop14 PF04147.12 EJS43865.1 - 0.017 13.3 22.7 0.019 13.2 22.7 1.0 1 0 0 1 1 1 0 Nop14-like family RAB3GAP2_C PF14656.6 EJS43865.1 - 0.029 12.6 1.8 0.033 12.4 1.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus UBN_AB PF14075.6 EJS43865.1 - 0.065 12.9 4.4 0.083 12.6 4.4 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Cwf_Cwc_15 PF04889.12 EJS43865.1 - 0.084 12.6 23.5 0.1 12.3 23.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PDDEXK_6 PF04720.12 EJS43865.1 - 0.15 12.0 9.1 0.18 11.8 9.1 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Mpp10 PF04006.12 EJS43865.1 - 0.15 10.4 22.6 0.18 10.2 22.6 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF2428 PF10350.9 EJS43865.1 - 0.31 10.3 2.5 0.33 10.2 2.5 1.2 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) RPN2_C PF18004.1 EJS43865.1 - 0.32 10.9 8.8 0.43 10.5 8.8 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 EJS43865.1 - 0.34 9.0 31.3 0.34 9.0 31.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi MIF4G_like_2 PF09090.11 EJS43865.1 - 0.49 9.8 4.6 0.56 9.6 4.6 1.1 1 0 0 1 1 1 0 MIF4G like DUF4192 PF13830.6 EJS43865.1 - 0.58 10.2 2.8 0.63 10.1 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF913 PF06025.12 EJS43865.1 - 0.69 8.8 4.7 0.7 8.8 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 EJS43865.1 - 0.85 8.9 20.1 0.93 8.8 20.1 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EJS43865.1 - 0.97 7.6 18.2 1 7.6 18.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EJS43865.1 - 1.1 7.7 18.3 1.2 7.7 18.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LegC3_N PF18654.1 EJS43865.1 - 1.9 7.6 12.9 2.2 7.4 12.9 1.1 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain CNDH2_C PF16858.5 EJS43865.1 - 2.2 8.1 15.6 2.5 7.9 15.6 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RNA_pol_Rpc4 PF05132.14 EJS43865.1 - 2.5 8.5 6.8 3.5 8.0 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 TRAP_alpha PF03896.16 EJS43865.1 - 2.9 7.0 13.5 3.3 6.8 13.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.8 EJS43865.1 - 3.1 6.6 9.2 3.4 6.5 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SAPS PF04499.15 EJS43865.1 - 3.9 6.1 8.6 4.1 6.1 8.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.12 EJS43865.1 - 4.3 6.6 21.2 4.9 6.5 21.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Myc_N PF01056.18 EJS43865.1 - 4.9 7.0 11.8 6.1 6.6 11.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NPR3 PF03666.13 EJS43865.1 - 6.4 5.4 7.1 6.8 5.4 7.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 EJS43865.1 - 6.5 6.1 25.1 7.4 5.9 25.1 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EJS43865.1 - 8.1 5.1 6.9 9.1 4.9 6.9 1.0 1 0 0 1 1 1 0 Presenilin HLH PF00010.26 EJS43866.1 - 2.9e-13 49.5 1.7 5.8e-13 48.6 0.4 2.3 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Mucin PF01456.17 EJS43866.1 - 7.9 6.5 23.3 2 8.4 1.4 2.5 3 0 0 3 3 3 0 Mucin-like glycoprotein ANAPC_CDC26 PF10471.9 EJS43867.1 - 3.7e-09 37.3 8.2 1.8e-08 35.1 8.2 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 DUF3295 PF11702.8 EJS43867.1 - 0.12 11.7 13.7 0.14 11.5 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CENP-B_dimeris PF09026.10 EJS43867.1 - 0.2 12.1 13.2 0.33 11.4 13.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 EJS43867.1 - 0.65 9.9 7.5 0.77 9.6 7.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.9 EJS43867.1 - 0.69 9.0 17.9 0.73 8.9 17.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 EJS43867.1 - 0.77 9.0 15.9 0.91 8.8 15.9 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EJS43867.1 - 2.9 6.0 15.0 3.4 5.8 15.0 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EJS43867.1 - 2.9 7.1 12.0 3.5 6.9 12.0 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EJS43867.1 - 3.7 5.5 17.6 4.3 5.3 17.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 EJS43867.1 - 3.8 5.5 9.3 3.8 5.5 9.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.11 EJS43867.1 - 3.8 5.9 11.7 4.2 5.8 11.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SWIRM PF04433.17 EJS43868.1 - 1.3e-28 99.2 0.3 3.9e-28 97.6 0.3 1.9 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.17 EJS43868.1 - 1.2e-17 63.4 3.5 1.9e-17 62.8 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 EJS43868.1 - 8.9e-10 38.6 0.1 1.9e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 EJS43868.1 - 8.8e-08 32.0 8.1 2.4e-07 30.6 8.1 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 EJS43868.1 - 2.7e-07 30.7 2.0 2e-06 27.9 0.1 3.3 4 1 0 4 4 4 1 Myb-like DNA-binding domain zf-UBR PF02207.20 EJS43868.1 - 0.0071 16.5 1.0 0.014 15.6 1.0 1.4 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-CCHC_2 PF13696.6 EJS43868.1 - 0.0091 15.8 2.9 0.55 10.1 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle Elf1 PF05129.13 EJS43868.1 - 0.033 14.2 0.4 0.084 12.9 0.4 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SANT_DAMP1_like PF16282.5 EJS43868.1 - 0.041 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 SNF2_N PF00176.23 EJS43869.1 - 1.5e-68 231.1 0.3 2.6e-68 230.3 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJS43869.1 - 1.1e-19 70.8 0.2 1.7e-18 67.0 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS43869.1 - 1.6e-09 38.0 0.5 1.1e-08 35.3 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EJS43869.1 - 5e-07 29.6 0.0 1.3e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EJS43869.1 - 0.0045 16.2 0.0 0.0045 16.2 0.0 2.4 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase CAMSAP_CKK PF08683.11 EJS43869.1 - 0.07 13.3 0.1 1.7 8.8 0.0 2.9 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated DUF5446 PF17522.2 EJS43870.1 - 0.01 16.0 5.3 0.034 14.3 0.5 3.2 2 1 0 2 2 2 0 Family of unknown function (DUF5446) ING PF12998.7 EJS43870.1 - 0.077 13.6 0.1 0.077 13.6 0.1 3.1 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding VP4_2 PF08935.10 EJS43870.1 - 0.085 13.5 0.0 0.28 11.8 0.0 1.9 1 0 0 1 1 1 0 Viral protein VP4 subunit DUF1351 PF07083.11 EJS43870.1 - 0.15 11.8 8.8 0.018 14.8 3.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1351) SAPS PF04499.15 EJS43871.1 - 8.5e-179 595.4 12.6 8.5e-179 595.4 12.6 4.0 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein DnaJ PF00226.31 EJS43872.1 - 1.7e-13 50.5 2.4 1.7e-13 50.5 2.4 1.8 2 0 0 2 2 2 1 DnaJ domain DUF1512 PF07431.12 EJS43872.1 - 0.07 12.1 0.1 0.15 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DUF4446 PF14584.6 EJS43872.1 - 1.1 9.2 4.7 1.6 8.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Thioredox_DsbH PF03190.15 EJS43873.1 - 0.024 14.6 0.1 0.035 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 PEN-2 PF10251.9 EJS43873.1 - 0.58 10.6 4.3 0.37 11.2 0.7 2.3 2 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Peptidase_M20 PF01546.28 EJS43874.1 - 2.6e-31 108.9 0.0 3.7e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJS43874.1 - 3e-10 40.0 0.0 4.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EJS43874.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Mito_carr PF00153.27 EJS43875.1 - 2.4e-36 123.5 6.4 3.5e-17 62.1 0.7 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Myc_N PF01056.18 EJS43876.1 - 0.23 11.3 9.4 0.33 10.8 9.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region QRPTase_C PF01729.19 EJS43877.1 - 3.8e-61 205.8 0.0 4.7e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EJS43877.1 - 2e-18 66.2 0.0 6.5e-18 64.6 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain IMPDH PF00478.25 EJS43877.1 - 0.096 11.7 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF155 PF02582.14 EJS43878.1 - 3.1e-52 177.2 0.1 6.3e-52 176.2 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 S36_mt PF10937.8 EJS43879.1 - 1e-30 107.7 0.1 1.3e-30 107.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Proteasome PF00227.26 EJS43880.1 - 7.5e-24 84.3 0.0 9.8e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Clat_adaptor_s PF01217.20 EJS43881.1 - 1e-08 35.2 2.9 2.1e-08 34.2 2.9 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.21 EJS43881.1 - 9e-08 31.8 0.1 1.4e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 EJS43881.1 - 0.058 12.8 0.1 0.2 11.1 0.1 1.8 1 1 0 1 1 1 0 Muniscin C-terminal mu homology domain AAA_assoc PF14363.6 EJS43881.1 - 0.072 13.4 0.3 0.31 11.4 0.3 2.2 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA CDC37_N PF03234.14 EJS43881.1 - 0.15 13.0 3.7 0.74 10.7 0.1 2.7 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding CSN8_PSD8_EIF3K PF10075.9 EJS43882.1 - 2.2e-19 69.9 2.4 3.9e-19 69.1 2.4 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EJS43882.1 - 9.9e-05 21.9 0.6 0.00013 21.5 0.6 1.1 1 0 0 1 1 1 1 SAC3/GANP family Hexokinase_2 PF03727.16 EJS43883.1 - 1e-78 264.1 0.0 2.9e-78 262.6 0.0 1.7 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 EJS43883.1 - 2.1e-72 243.2 0.0 3.9e-72 242.3 0.0 1.4 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.21 EJS43883.1 - 0.0049 16.5 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Acetyltransf_13 PF13880.6 EJS43884.1 - 5.1e-21 74.4 0.0 1.4e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EJS43884.1 - 2.6e-10 39.9 0.4 4.6e-10 39.2 0.4 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 EJS43884.1 - 0.0042 17.3 0.0 0.0075 16.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJS43884.1 - 0.013 16.0 0.1 0.038 14.4 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain BIR PF00653.21 EJS43884.1 - 0.13 13.0 0.0 0.24 12.1 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain ECH_1 PF00378.20 EJS43884.1 - 0.17 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DSPn PF14671.6 EJS43885.1 - 2.7e-45 154.3 0.1 7.9e-45 152.8 0.1 1.9 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EJS43885.1 - 2e-25 89.1 0.0 1.2e-24 86.7 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EJS43885.1 - 0.0008 19.1 0.5 0.0019 17.9 0.1 1.8 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 EJS43885.1 - 0.00086 18.9 0.8 0.0013 18.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EJS43885.1 - 0.037 14.1 0.0 0.095 12.8 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Rtf2 PF04641.12 EJS43886.1 - 4.7 6.5 6.4 12 5.2 6.4 1.7 1 1 0 1 1 1 0 Rtf2 RING-finger FAD_binding_1 PF00667.20 EJS43887.1 - 1e-74 250.9 0.0 1.6e-74 250.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EJS43887.1 - 8.2e-08 32.9 0.0 2.7e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain SMC_N PF02463.19 EJS43888.1 - 1.4e-74 250.2 0.0 2.7e-42 144.7 0.0 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EJS43888.1 - 1.7e-23 83.2 0.0 4.7e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 EJS43888.1 - 2.7e-14 53.7 1.8 2.7e-14 53.7 1.8 4.4 2 2 1 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 EJS43888.1 - 5e-07 29.8 17.5 5.8e-05 23.1 0.3 3.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system GAS PF13851.6 EJS43888.1 - 1.7e-06 27.6 24.1 1.5e-05 24.4 3.6 8.1 3 2 4 7 7 7 2 Growth-arrest specific micro-tubule binding AAA_29 PF13555.6 EJS43888.1 - 5.5e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EJS43888.1 - 0.00021 21.8 46.8 0.00021 21.8 46.8 6.8 2 2 1 3 3 3 1 AAA domain Hema_HEFG PF02710.14 EJS43888.1 - 0.0081 16.4 0.2 0.028 14.6 0.0 2.0 2 0 0 2 2 2 1 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein ABC_tran PF00005.27 EJS43888.1 - 0.59 10.6 0.0 0.59 10.6 0.0 6.1 4 2 0 4 4 4 0 ABC transporter HLH PF00010.26 EJS43888.1 - 3 7.9 9.6 7 6.7 0.2 4.1 3 0 0 3 3 3 0 Helix-loop-helix DNA-binding domain Glycogen_syn PF05693.13 EJS43889.1 - 0 1170.8 0.1 0 1170.7 0.1 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 EJS43889.1 - 1.2e-08 34.7 0.0 1.6e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EJS43889.1 - 1.6e-06 28.6 0.0 0.00084 19.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EJS43889.1 - 9.7e-05 22.4 0.2 0.00022 21.2 0.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 EJS43889.1 - 0.00038 20.2 0.1 0.00075 19.3 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 EJS43889.1 - 0.0049 17.3 0.0 0.0094 16.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Pkinase PF00069.25 EJS43890.1 - 5.6e-71 239.0 0.0 9.3e-71 238.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43890.1 - 2.7e-38 131.8 0.0 3.8e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS43890.1 - 2.8e-05 23.6 0.0 0.011 15.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EJS43890.1 - 0.0074 15.1 0.2 0.022 13.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EJS43890.1 - 0.042 13.2 0.1 0.075 12.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1690 PF07956.11 EJS43891.1 - 1.6e-40 138.8 15.8 3e-40 137.9 15.8 1.4 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) STN1_2 PF09170.10 EJS43891.1 - 0.56 10.4 5.7 0.87 9.8 5.6 1.5 1 1 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 UCH PF00443.29 EJS43892.1 - 3.7e-50 170.8 5.4 5.3e-50 170.3 5.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJS43892.1 - 1.3e-11 44.7 13.3 6.7e-10 39.1 13.3 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EJS43892.1 - 0.00015 21.5 0.1 0.001 18.7 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family DUF1700 PF08006.11 EJS43892.1 - 0.17 11.4 0.1 0.52 9.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) ABC_tran PF00005.27 EJS43893.1 - 3.2e-47 160.5 1.5 5.8e-23 81.9 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EJS43893.1 - 6.8e-19 67.7 8.7 6.8e-19 67.7 8.7 2.6 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.6 EJS43893.1 - 7.5e-17 62.1 11.8 3.2e-05 23.9 0.0 5.3 3 2 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJS43893.1 - 6.4e-11 42.1 0.0 0.00094 18.7 0.0 3.6 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EJS43893.1 - 6.5e-07 29.7 1.6 0.049 13.9 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EJS43893.1 - 1.3e-06 28.8 0.3 0.091 13.0 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EJS43893.1 - 2e-06 28.3 2.5 0.16 12.5 0.1 4.5 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.6 EJS43893.1 - 4.4e-06 26.3 0.0 0.13 12.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EJS43893.1 - 4.7e-06 26.6 21.5 0.016 14.9 0.0 4.8 4 1 0 4 4 4 2 AAA ATPase domain AAA_16 PF13191.6 EJS43893.1 - 5.5e-06 26.9 0.2 0.12 12.7 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain NACHT PF05729.12 EJS43893.1 - 1e-05 25.5 0.0 0.068 13.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 EJS43893.1 - 1.8e-05 24.7 0.0 0.076 12.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EJS43893.1 - 2.9e-05 24.1 0.4 0.12 12.5 0.1 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_14 PF13173.6 EJS43893.1 - 4.5e-05 23.5 0.1 0.58 10.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 EJS43893.1 - 5.2e-05 23.7 0.2 0.15 12.5 0.0 3.5 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EJS43893.1 - 8.3e-05 22.8 0.0 0.27 11.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EJS43893.1 - 0.00021 21.1 0.0 0.62 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 EJS43893.1 - 0.00026 20.7 0.0 0.066 12.9 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 EJS43893.1 - 0.00033 21.2 26.6 0.12 12.9 0.0 5.3 5 0 0 5 5 5 2 AAA domain NTPase_1 PF03266.15 EJS43893.1 - 0.00043 20.2 0.0 0.31 10.9 0.0 2.7 2 0 0 2 2 2 1 NTPase PduV-EutP PF10662.9 EJS43893.1 - 0.00043 20.0 0.4 0.45 10.2 0.1 3.0 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 EJS43893.1 - 0.00051 19.8 0.0 0.41 10.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 EJS43893.1 - 0.00052 20.4 0.4 0.79 10.1 0.0 3.2 3 0 0 3 3 2 1 RNA helicase Roc PF08477.13 EJS43893.1 - 0.0019 18.4 0.1 3.2 8.0 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 EJS43893.1 - 0.0019 18.2 1.0 4.3 7.3 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EJS43893.1 - 0.002 17.6 0.0 0.99 8.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MeaB PF03308.16 EJS43893.1 - 0.0021 17.1 0.0 0.28 10.1 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 EJS43893.1 - 0.0029 17.6 0.0 0.72 9.9 0.0 2.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 EJS43893.1 - 0.0049 16.1 3.7 0.46 9.6 0.0 3.0 3 0 0 3 3 3 1 G-protein alpha subunit Zeta_toxin PF06414.12 EJS43893.1 - 0.0071 15.6 0.0 2.2 7.5 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 EJS43893.1 - 0.011 14.9 0.0 4.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 EJS43893.1 - 0.014 14.5 4.7 0.61 9.2 0.0 3.1 3 1 0 3 3 3 0 NB-ARC domain MobB PF03205.14 EJS43893.1 - 0.015 15.2 0.0 0.5 10.3 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.18 EJS43893.1 - 0.017 14.4 0.3 4.1 6.6 0.1 2.8 2 1 0 2 2 2 0 Septin SbcCD_C PF13558.6 EJS43893.1 - 0.019 15.2 0.1 20 5.5 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FeoB_N PF02421.18 EJS43893.1 - 0.019 14.5 0.0 6.7 6.2 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.6 EJS43893.1 - 0.02 14.5 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EJS43893.1 - 0.025 14.6 4.4 0.2 11.7 0.0 3.6 4 1 0 4 4 4 0 Dynamin family SRP54 PF00448.22 EJS43893.1 - 0.028 14.1 0.0 2.5 7.7 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 EJS43893.1 - 0.028 14.3 4.7 2 8.3 0.0 3.2 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 EJS43893.1 - 0.029 14.0 0.7 12 5.4 0.0 3.8 3 1 1 4 4 4 0 AAA domain Pox_A32 PF04665.12 EJS43893.1 - 0.041 13.3 1.0 0.9 8.9 0.0 2.9 3 0 0 3 3 3 0 Poxvirus A32 protein cobW PF02492.19 EJS43893.1 - 0.064 12.8 0.1 7.1 6.2 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 EJS43893.1 - 0.072 12.0 0.3 0.38 9.6 0.0 2.2 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.18 EJS43893.1 - 0.079 12.7 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EJS43893.1 - 0.12 12.8 2.9 19 5.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF2813 PF11398.8 EJS43893.1 - 0.25 10.6 0.0 0.25 10.6 0.0 4.1 4 1 0 5 5 5 0 Protein of unknown function (DUF2813) PIP5K PF01504.18 EJS43894.1 - 5.7e-42 143.8 20.1 3.1e-36 125.0 2.2 4.9 3 1 1 4 4 4 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EJS43894.1 - 9.3e-25 87.2 0.0 2e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EJS43894.1 - 8.6e-17 61.0 10.4 2.6e-16 59.5 10.4 1.9 1 0 0 1 1 1 1 FYVE zinc finger SUIM_assoc PF16619.5 EJS43894.1 - 0.00079 19.4 3.5 0.0037 17.3 3.5 2.2 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF1689 PF07954.11 EJS43894.1 - 0.45 10.9 4.9 20 5.6 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1689) IBR PF01485.21 EJS43894.1 - 1.8 8.8 9.1 0.52 10.6 4.8 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain WD40 PF00400.32 EJS43895.1 - 3.5e-07 30.8 0.0 0.11 13.5 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS43895.1 - 1.3e-05 25.4 0.0 0.053 13.8 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 EJS43895.1 - 0.0058 16.3 0.1 0.059 13.0 0.0 2.3 2 1 0 2 2 2 1 CNH domain Ge1_WD40 PF16529.5 EJS43895.1 - 0.03 13.3 0.5 0.15 11.0 0.1 2.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EJS43895.1 - 0.1 11.9 2.6 0.92 8.8 0.0 3.0 3 0 0 3 3 3 0 WD40-like domain Arrestin_C PF02752.22 EJS43896.1 - 1.5e-23 83.7 0.2 4.5e-23 82.2 0.1 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EJS43896.1 - 3.1e-09 37.0 0.0 5.7e-08 32.9 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EJS43896.1 - 0.0019 17.9 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like RRM_1 PF00076.22 EJS43897.1 - 2.9e-51 171.2 10.3 2e-20 72.4 0.2 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJS43897.1 - 9.9e-06 25.2 0.1 0.2 11.3 0.0 3.6 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EJS43897.1 - 2e-05 24.5 1.2 1.4 9.0 0.0 4.6 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 EJS43897.1 - 6.5e-05 22.8 1.1 0.029 14.4 0.0 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EJS43897.1 - 0.00013 21.8 0.0 1.4 8.8 0.0 3.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EJS43897.1 - 0.00016 21.6 1.6 11 6.2 0.1 5.1 4 2 0 4 4 4 1 Limkain b1 SET_assoc PF11767.8 EJS43897.1 - 0.0033 17.0 1.1 9.8 5.9 0.0 3.5 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated RL PF17797.1 EJS43897.1 - 0.006 16.5 2.8 6.4 6.8 0.0 3.9 4 0 0 4 4 4 1 RL domain RRM_Rrp7 PF17799.1 EJS43897.1 - 0.011 15.6 4.3 0.039 13.7 0.1 3.3 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain NDK PF00334.19 EJS43897.1 - 0.018 15.1 0.1 0.041 13.9 0.1 1.6 1 0 0 1 1 1 0 Nucleoside diphosphate kinase DbpA PF03880.15 EJS43897.1 - 0.041 13.9 0.3 1.5 8.9 0.0 3.2 3 0 0 3 3 3 0 DbpA RNA binding domain HpaB_N PF11794.8 EJS43897.1 - 0.095 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PHP PF02811.19 EJS43898.1 - 1e-10 42.2 0.2 1.9e-10 41.3 0.2 1.4 1 1 0 1 1 1 1 PHP domain Spectrin_like PF18373.1 EJS43898.1 - 0.082 13.0 0.8 0.84 9.7 0.0 2.7 3 1 0 3 3 3 0 Spectrin like domain VTC PF09359.10 EJS43899.1 - 1.1e-96 323.4 0.5 1.1e-96 323.4 0.5 2.0 3 0 0 3 3 3 1 VTC domain DUF202 PF02656.15 EJS43899.1 - 1.8e-11 44.3 2.6 1.9e-11 44.2 0.4 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EJS43899.1 - 3.8e-11 43.5 25.0 0.00079 19.5 2.5 4.5 2 1 2 4 4 4 3 SPX domain MBOAT PF03062.19 EJS43899.1 - 0.00045 19.7 0.5 0.00082 18.8 0.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CPSase_L_D3 PF02787.19 EJS43899.1 - 0.14 12.5 1.2 0.34 11.2 0.1 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GNAT_acetyltran PF12746.7 EJS43899.1 - 1.4 8.4 4.1 0.86 9.1 0.8 2.2 2 0 0 2 2 2 0 GNAT acetyltransferase Cation_efflux PF01545.21 EJS43899.1 - 1.7 8.3 3.7 28 4.4 3.7 2.1 1 1 0 1 1 1 0 Cation efflux family DEAD PF00270.29 EJS43900.1 - 1e-41 142.6 0.0 1.8e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS43900.1 - 1.3e-23 83.4 0.1 6.5e-23 81.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EJS43900.1 - 7.2e-19 67.8 0.1 1.7e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EJS43900.1 - 4.3e-05 23.6 0.7 0.00047 20.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EJS43900.1 - 0.00086 18.6 3.5 0.0011 18.2 0.0 2.7 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase Nic96 PF04097.14 EJS43901.1 - 1.3e-198 661.4 5.7 1.9e-198 660.9 5.7 1.2 1 0 0 1 1 1 1 Nup93/Nic96 HHH_4 PF14490.6 EJS43901.1 - 0.0093 15.9 0.1 0.27 11.2 0.0 3.0 3 0 0 3 3 3 1 Helix-hairpin-helix containing domain JAB PF01398.21 EJS43902.1 - 6.5e-32 110.0 0.2 6.5e-32 110.0 0.2 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EJS43902.1 - 1.5e-10 41.4 1.6 3.5e-10 40.3 1.6 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EJS43902.1 - 2.6e-07 30.4 0.0 4.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-UBP PF02148.19 EJS43903.1 - 8.7e-08 32.4 1.7 2.5e-07 30.9 1.7 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.29 EJS43903.1 - 2.1e-06 27.5 2.0 1.6e-05 24.6 2.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GHD PF17834.1 EJS43903.1 - 0.063 13.3 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase Peptidase_M24 PF00557.24 EJS43904.1 - 1.8e-60 204.3 0.0 2.3e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EJS43904.1 - 2.8e-23 82.0 0.0 6.2e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain AAA_16 PF13191.6 EJS43905.1 - 1.9e-06 28.4 0.0 3.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EJS43905.1 - 8.5e-05 22.7 0.0 0.003 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EJS43905.1 - 8.6e-05 22.6 0.0 0.00036 20.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) PRK PF00485.18 EJS43905.1 - 0.00034 20.4 0.0 0.36 10.5 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family 6PF2K PF01591.18 EJS43905.1 - 0.00062 19.1 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.6 EJS43905.1 - 0.00065 20.2 0.0 0.004 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EJS43905.1 - 0.00094 18.5 0.0 0.0027 17.0 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin KTI12 PF08433.10 EJS43905.1 - 0.002 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 EJS43905.1 - 0.0021 18.3 0.0 0.0081 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EJS43905.1 - 0.0023 18.0 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 EJS43905.1 - 0.0044 17.4 0.0 0.011 16.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EJS43905.1 - 0.0077 16.6 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 EJS43905.1 - 0.0078 15.4 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Mg_chelatase PF01078.21 EJS43905.1 - 0.0082 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 EJS43905.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 EJS43905.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EJS43905.1 - 0.031 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EJS43905.1 - 0.032 14.7 0.2 0.06 13.9 0.2 1.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 EJS43905.1 - 0.038 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Ploopntkinase3 PF18751.1 EJS43905.1 - 0.038 13.9 0.0 0.098 12.6 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 EJS43905.1 - 0.041 13.6 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EJS43905.1 - 0.057 12.9 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EJS43905.1 - 0.075 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.6 EJS43905.1 - 0.094 13.1 0.0 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EJS43905.1 - 0.097 12.6 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 EJS43905.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EJS43905.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EJS43905.1 - 0.1 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EJS43905.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_15 PF13175.6 EJS43905.1 - 0.11 12.1 0.0 1.9 8.1 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain Microtub_bd PF16796.5 EJS43905.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding APS_kinase PF01583.20 EJS43905.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase FAM195 PF14799.6 EJS43906.1 - 0.31 11.4 6.1 2.7 8.4 2.5 2.5 2 1 0 2 2 2 0 FAM195 family GTSE1_N PF15259.6 EJS43906.1 - 0.76 10.0 6.7 0.55 10.4 4.6 1.9 2 1 0 2 2 2 0 G-2 and S-phase expressed 1 Pyr_redox_2 PF07992.14 EJS43907.1 - 2.6e-66 223.8 6.0 2.6e-66 223.8 6.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EJS43907.1 - 5.6e-44 148.9 0.8 1.3e-43 147.7 0.1 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EJS43907.1 - 1.2e-21 77.1 6.8 2e-18 66.7 1.0 3.4 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJS43907.1 - 3.5e-12 46.4 0.8 8.3e-06 26.0 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EJS43907.1 - 1.3e-10 41.0 6.6 8.8e-07 28.5 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EJS43907.1 - 1.9e-10 40.7 8.8 5.5e-10 39.2 0.1 2.9 3 1 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EJS43907.1 - 6.3e-10 38.7 9.7 7.3e-10 38.5 2.6 2.6 2 2 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EJS43907.1 - 2.3e-08 33.6 0.1 2.3e-08 33.6 0.1 2.6 2 1 1 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 EJS43907.1 - 1.2e-07 31.2 1.5 0.0073 15.6 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EJS43907.1 - 1.5e-07 31.0 5.0 0.00079 18.8 0.3 2.9 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EJS43907.1 - 2.7e-06 26.3 14.6 3.2e-05 22.8 0.9 4.5 4 1 1 5 5 5 2 HI0933-like protein Thi4 PF01946.17 EJS43907.1 - 0.0001 21.6 0.6 0.0025 17.1 0.0 2.4 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EJS43907.1 - 0.00032 20.0 1.5 0.92 8.6 0.1 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EJS43907.1 - 0.00056 19.6 17.4 0.13 11.8 3.4 4.3 2 2 2 4 4 4 2 FAD dependent oxidoreductase XdhC_C PF13478.6 EJS43907.1 - 0.011 16.2 0.0 7 7.2 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain THF_DHG_CYH_C PF02882.19 EJS43907.1 - 0.013 14.9 1.6 0.022 14.1 0.4 2.2 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EJS43907.1 - 0.014 15.3 0.5 0.014 15.3 0.5 2.6 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EJS43907.1 - 0.053 12.6 3.2 0.31 10.0 0.2 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EJS43907.1 - 0.083 13.3 1.2 3.4 8.2 0.2 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding AIRC PF00731.20 EJS43907.1 - 0.11 12.0 1.4 0.2 11.2 0.1 2.2 2 1 0 2 2 2 0 AIR carboxylase UDPG_MGDP_dh_N PF03721.14 EJS43907.1 - 0.17 11.5 6.8 0.4 10.2 1.8 2.7 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 EJS43907.1 - 0.34 9.7 5.9 0.12 11.3 0.3 2.3 3 0 0 3 3 3 0 Tryptophan halogenase PTS_IIB PF02302.17 EJS43907.1 - 0.6 10.8 4.9 6.8 7.5 0.4 3.1 3 1 0 3 3 2 0 PTS system, Lactose/Cellobiose specific IIB subunit LSM PF01423.22 EJS43908.1 - 1.7e-17 62.8 0.1 1.9e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EJS43908.1 - 0.09 12.9 0.0 0.099 12.8 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Acetyltransf_1 PF00583.25 EJS43909.1 - 1.4e-16 60.8 0.0 1.8e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJS43909.1 - 2.6e-11 43.8 0.0 3.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EJS43909.1 - 5.4e-09 36.1 0.0 7.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EJS43909.1 - 0.033 14.3 0.5 0.17 12.0 0.5 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJS43909.1 - 0.041 14.0 0.1 0.19 11.8 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaJ_C PF01556.18 EJS43910.1 - 4.6e-27 94.9 0.2 7.7e-27 94.2 0.2 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EJS43910.1 - 6.8e-25 87.0 5.2 1.4e-24 86.0 5.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EJS43910.1 - 9.8e-11 41.9 20.9 1.8e-10 41.0 20.9 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EJS43910.1 - 0.018 15.0 7.6 0.19 11.8 1.9 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 EJS43910.1 - 0.5 10.4 13.6 11 6.2 13.6 2.6 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c DUF2318 PF10080.9 EJS43910.1 - 3.6 7.8 6.9 2.7 8.2 3.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Cytochrome_CBB3 PF13442.6 EJS43910.1 - 4.1 7.8 11.5 6 7.3 1.4 3.0 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III zinc-ribbons_6 PF07191.12 EJS43910.1 - 4.4 7.3 7.2 14 5.8 1.8 1.9 1 1 1 2 2 2 0 zinc-ribbons HSP9_HSP12 PF04119.12 EJS43911.1 - 2e-26 92.2 4.1 3.3e-26 91.4 1.2 2.3 2 1 0 2 2 2 1 Heat shock protein 9/12 DUF357 PF04010.13 EJS43911.1 - 0.048 13.7 0.1 0.82 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF883 PF05957.13 EJS43911.1 - 0.077 13.6 0.7 0.27 11.9 0.7 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EJS43911.1 - 0.41 11.2 6.3 1.1 9.9 0.5 2.2 1 1 1 2 2 2 0 YtxH-like protein DUF2585 PF10755.9 EJS43912.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) Sugar_tr PF00083.24 EJS43913.1 - 7.1e-167 555.8 34.2 8.1e-167 555.6 34.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS43913.1 - 6.9e-38 130.5 43.7 5.9e-31 107.7 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.6 EJS43913.1 - 5.3 7.3 7.3 2.9 8.1 1.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) WW PF00397.26 EJS43914.1 - 2.1e-10 40.5 2.4 2.1e-10 40.5 2.4 2.2 2 0 0 2 2 2 1 WW domain Endostatin PF06482.11 EJS43914.1 - 0.13 11.7 1.4 0.16 11.4 1.4 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Pex14_N PF04695.13 EJS43914.1 - 0.33 11.6 20.5 0.49 11.0 20.3 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 EJS43914.1 - 3.7 7.5 39.0 0.055 13.5 26.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) PAT1 PF09770.9 EJS43914.1 - 6.4 4.9 8.9 6.9 4.8 8.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 EJS43914.1 - 6.5 6.6 14.4 7.2 6.5 14.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 EJS43915.1 - 2.9e-34 116.5 19.6 3e-06 27.9 0.7 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat CDC4_D PF16856.5 EJS43915.1 - 1.4e-20 72.9 0.3 3.6e-20 71.6 0.3 1.7 1 0 0 1 1 1 1 Cell division control protein 4 dimerisation domain F-box-like PF12937.7 EJS43915.1 - 1.1e-07 31.6 0.1 2.3e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EJS43915.1 - 4.4e-06 26.9 1.0 0.58 10.5 0.1 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EJS43915.1 - 0.0017 18.2 0.3 0.0017 18.2 0.3 2.0 2 0 0 2 2 2 1 F-box domain WD40_like PF17005.5 EJS43915.1 - 0.0042 16.4 1.7 13 5.0 0.1 3.8 2 1 2 4 4 4 1 WD40-like domain PQQ_2 PF13360.6 EJS43915.1 - 0.01 15.5 0.0 0.077 12.6 0.0 2.4 3 0 0 3 3 3 0 PQQ-like domain DED PF01335.21 EJS43915.1 - 0.13 12.6 0.5 0.33 11.3 0.5 1.7 1 0 0 1 1 1 0 Death effector domain tRNA-synt_2d PF01409.20 EJS43916.1 - 2e-90 302.5 0.0 2.6e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EJS43916.1 - 2.1e-13 50.3 1.6 3.9e-13 49.5 0.3 2.2 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EJS43916.1 - 6.9e-08 32.2 0.0 4.6e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 EJS43916.1 - 1.5e-07 31.2 1.2 1.5e-07 31.2 1.2 2.2 2 0 0 2 2 2 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 EJS43916.1 - 1.1e-05 25.5 0.0 3.1e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EJS43916.1 - 6e-05 22.3 0.2 0.0014 17.7 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_His PF13393.6 EJS43916.1 - 0.043 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Histidyl-tRNA synthetase HTH_45 PF14947.6 EJS43916.1 - 0.091 12.8 1.3 8.7 6.4 0.1 2.7 2 1 0 2 2 2 0 Winged helix-turn-helix SRP1_TIP1 PF00660.17 EJS43917.1 - 4.5e-27 94.0 0.1 6e-27 93.6 0.1 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family CRC_subunit PF08624.10 EJS43918.1 - 9.8e-38 129.6 1.0 2.5e-37 128.3 1.0 1.7 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF1640 PF07798.11 EJS43919.1 - 2.7e-52 177.3 9.2 3.4e-52 177.0 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3584 PF12128.8 EJS43919.1 - 0.011 13.3 7.9 0.014 13.0 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 EJS43919.1 - 0.013 15.9 2.8 1.8 9.1 0.1 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 EJS43919.1 - 0.032 14.5 8.7 0.75 10.1 8.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) FTA4 PF13093.6 EJS43919.1 - 0.041 13.8 6.1 0.049 13.5 6.1 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sulfatase_C PF14707.6 EJS43919.1 - 0.053 14.3 1.5 4.7 8.0 0.0 2.5 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase ZnuA PF01297.17 EJS43919.1 - 0.093 12.1 2.5 0.31 10.4 2.5 1.8 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic PIN_8 PF18476.1 EJS43919.1 - 0.14 12.0 6.5 0.22 11.4 6.4 1.3 1 1 0 1 1 1 0 PIN like domain DUF4407 PF14362.6 EJS43919.1 - 0.19 11.0 4.5 0.26 10.6 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 EJS43919.1 - 0.27 11.5 0.1 0.27 11.5 0.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Uso1_p115_C PF04871.13 EJS43919.1 - 0.27 11.6 7.5 0.22 11.9 3.2 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Baculo_PEP_C PF04513.12 EJS43919.1 - 0.28 11.2 6.6 1.4 9.0 2.5 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tup_N PF08581.10 EJS43919.1 - 0.35 11.2 9.5 2.4 8.5 1.1 2.7 2 1 0 2 2 2 0 Tup N-terminal HU-CCDC81_bac_2 PF18175.1 EJS43919.1 - 0.36 10.7 5.5 0.82 9.6 0.5 3.2 2 1 2 4 4 4 0 CCDC81-like prokaryotic HU domain 2 Phage_lysis PF03245.13 EJS43919.1 - 0.58 10.3 7.5 0.52 10.4 0.9 2.2 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein Phage_Mu_Gam PF07352.12 EJS43919.1 - 0.73 9.7 8.0 0.18 11.7 0.7 2.3 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Fib_alpha PF08702.10 EJS43919.1 - 1.6 8.9 10.7 0.47 10.6 6.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EJS43919.1 - 2.1 8.4 9.1 6.6 6.8 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PMM PF03332.13 EJS43920.1 - 1.2e-114 381.7 0.3 1.3e-114 381.5 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EJS43920.1 - 3.3e-05 23.8 0.0 0.0016 18.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.13 EJS43920.1 - 0.18 11.0 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein OTU PF02338.19 EJS43921.1 - 1.7e-08 35.0 0.0 2.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EJS43921.1 - 0.037 13.5 0.4 0.11 11.9 0.1 1.9 2 1 0 2 2 2 0 Peptidase C65 Otubain Sugar_tr PF00083.24 EJS43922.1 - 2.3e-61 208.0 25.3 3e-61 207.7 25.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS43922.1 - 3.9e-14 52.3 34.6 3.2e-12 46.0 25.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ras PF00071.22 EJS43923.1 - 2.7e-64 215.7 0.5 3.2e-64 215.4 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS43923.1 - 8.3e-36 122.8 1.1 8.4e-36 122.8 0.2 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS43923.1 - 6.4e-17 61.5 0.4 8.7e-17 61.1 0.3 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EJS43923.1 - 8.6e-06 25.3 0.2 1.3e-05 24.6 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EJS43923.1 - 2.1e-05 24.2 0.3 5.1e-05 22.9 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EJS43923.1 - 0.00016 21.7 0.2 0.00026 21.0 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EJS43923.1 - 0.0026 17.2 0.9 0.0028 17.1 0.1 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EJS43923.1 - 0.0034 17.3 0.7 0.1 12.5 0.1 2.3 1 1 1 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 EJS43923.1 - 0.015 14.8 0.8 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Septin PF00735.18 EJS43923.1 - 0.029 13.7 0.2 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_5 PF07728.14 EJS43923.1 - 0.061 13.3 0.1 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PcfK PF14058.6 EJS43923.1 - 0.062 13.6 0.3 0.09 13.1 0.3 1.2 1 0 0 1 1 1 0 PcfK-like protein ABC_tran PF00005.27 EJS43923.1 - 0.072 13.6 1.0 0.29 11.7 1.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EJS43923.1 - 0.086 13.2 0.0 0.13 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EJS43923.1 - 0.088 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EJS43923.1 - 0.1 13.0 0.1 1 9.8 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EJS43923.1 - 0.13 12.5 0.1 0.39 11.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain Tubulin PF00091.25 EJS43924.1 - 6.7e-69 232.0 0.0 1.2e-68 231.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EJS43924.1 - 4e-42 143.3 0.1 7.6e-42 142.4 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EJS43924.1 - 0.0024 17.6 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EJS43924.1 - 0.0048 16.1 0.1 0.011 15.0 0.0 1.6 2 0 0 2 2 2 1 Tubulin like Misat_Tub_SegII PF10644.9 EJS43924.1 - 0.026 14.8 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain RNA_pol PF00940.19 EJS43925.1 - 2e-177 590.2 0.0 2.9e-177 589.6 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EJS43925.1 - 6.7e-105 351.2 0.3 1.3e-104 350.2 0.3 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DUF726 PF05277.12 EJS43926.1 - 2.4e-142 473.9 2.8 4.1e-142 473.1 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) MerR_2 PF13591.6 EJS43926.1 - 0.089 12.7 0.1 4.3 7.3 0.1 2.6 2 0 0 2 2 2 0 MerR HTH family regulatory protein DUF4710 PF15828.5 EJS43926.1 - 0.52 10.5 2.9 0.81 9.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Aminotran_5 PF00266.19 EJS43927.1 - 1.4e-23 83.5 0.0 1.8e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Pkinase PF00069.25 EJS43928.1 - 8.6e-27 94.1 0.0 9.1e-26 90.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS43928.1 - 7.7e-14 51.6 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJS43928.1 - 1.6e-06 27.1 0.0 2.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EJS43928.1 - 0.0029 17.2 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 EJS43928.1 - 0.0068 16.4 0.0 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family FAM150 PF15129.6 EJS43928.1 - 0.086 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 FAM150 family Lambda_Bor PF06291.11 EJS43928.1 - 0.11 12.6 0.0 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Bor protein Kdo PF06293.14 EJS43928.1 - 0.22 10.9 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 EJS43929.1 - 3.6e-17 63.2 0.0 8.8e-17 61.9 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EJS43929.1 - 6.4e-10 39.3 0.4 0.0012 18.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJS43929.1 - 4.6e-05 23.0 0.0 0.15 11.5 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EJS43929.1 - 0.0041 16.8 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EJS43929.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 EJS43929.1 - 0.03 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_23 PF13476.6 EJS43929.1 - 0.035 14.6 0.0 0.044 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EJS43929.1 - 0.042 13.7 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 EJS43929.1 - 0.052 13.5 1.7 16 5.5 0.0 3.1 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EJS43929.1 - 0.073 13.6 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EJS43929.1 - 0.095 11.7 0.0 0.18 10.7 0.0 1.4 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_10 PF12846.7 EJS43929.1 - 0.11 11.4 0.4 0.39 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.23 EJS43929.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3584 PF12128.8 EJS43929.1 - 0.14 9.7 0.1 0.18 9.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_27 PF13514.6 EJS43929.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.18 EJS43930.1 - 2.1e-09 37.4 6.9 4e-09 36.5 6.7 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain STE2 PF02116.15 EJS43931.1 - 2.3e-87 292.9 25.1 2.7e-87 292.6 25.1 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Mannosyl_trans4 PF15971.5 EJS43931.1 - 0.01 15.7 1.9 0.01 15.7 1.9 2.1 2 0 0 2 2 2 1 DolP-mannose mannosyltransferase DUF2976 PF11190.8 EJS43931.1 - 2.3 8.1 5.7 5.2 6.9 2.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) PGAP1 PF07819.13 EJS43932.1 - 5.1e-96 320.9 0.0 9.5e-96 320.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EJS43932.1 - 0.00018 21.3 0.0 0.00056 19.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EJS43932.1 - 0.00036 21.2 0.0 0.00059 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EJS43932.1 - 0.0028 17.6 0.0 0.0056 16.5 0.0 1.5 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 EJS43932.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EJS43932.1 - 0.031 13.8 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 EJS43932.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family AA_permease PF00324.21 EJS43933.1 - 5.5e-127 424.3 39.3 6.3e-127 424.1 39.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS43933.1 - 1.1e-32 113.4 42.3 1.6e-32 112.9 41.9 1.4 1 1 0 1 1 1 1 Amino acid permease Dak1 PF02733.17 EJS43934.1 - 2.1e-109 365.2 2.2 2.7e-109 364.8 2.2 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EJS43934.1 - 2.3e-44 151.3 2.8 5.2e-44 150.2 2.8 1.6 1 0 0 1 1 1 1 DAK2 domain Sugar_tr PF00083.24 EJS43935.1 - 1.8e-78 264.4 30.0 2.2e-78 264.1 30.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS43935.1 - 4.4e-28 98.2 55.3 9e-20 70.9 32.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DMT_YdcZ PF04657.13 EJS43935.1 - 0.00081 19.7 0.8 0.00081 19.7 0.8 3.6 3 1 0 3 3 3 1 Putative inner membrane exporter, YdcZ BT1 PF03092.16 EJS43935.1 - 0.0027 16.0 4.2 0.016 13.5 0.2 2.2 2 0 0 2 2 2 2 BT1 family MFS_2 PF13347.6 EJS43935.1 - 0.17 10.4 25.6 0.71 8.4 0.2 3.4 2 1 1 3 3 3 0 MFS/sugar transport protein MFS_3 PF05977.13 EJS43935.1 - 0.27 9.6 4.9 0.078 11.4 0.7 2.1 3 0 0 3 3 3 0 Transmembrane secretion effector JSRP PF15312.6 EJS43935.1 - 0.62 10.0 1.7 2.2 8.2 0.8 2.0 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein 5-FTHF_cyc-lig PF01812.20 EJS43936.1 - 3.4e-58 196.6 0.0 4.5e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RRM_1 PF00076.22 EJS43937.1 - 1.3e-85 281.3 4.9 1.5e-21 76.0 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EJS43937.1 - 1.5e-18 66.7 3.2 2.5e-18 66.0 0.2 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EJS43937.1 - 2e-10 40.3 0.0 0.058 13.0 0.0 4.2 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJS43937.1 - 1.4e-06 28.3 0.8 0.053 13.7 0.0 5.0 4 3 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 EJS43937.1 - 1.1e-05 25.4 4.8 0.12 12.4 1.6 4.7 3 1 1 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 EJS43937.1 - 4e-05 23.5 1.3 0.49 10.4 0.0 3.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EJS43937.1 - 0.0001 22.1 0.1 0.17 11.7 0.0 4.1 4 0 0 4 4 4 1 Occluded RNA-recognition motif YflT PF11181.8 EJS43937.1 - 0.0011 19.4 11.2 0.019 15.5 1.0 3.9 3 1 1 4 4 4 1 Heat induced stress protein YflT DUF4523 PF15023.6 EJS43937.1 - 0.01 15.7 0.0 8.4 6.2 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4523) OB_RNB PF08206.11 EJS43937.1 - 0.02 14.6 3.8 8.5 6.2 0.3 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain PolyA_pol PF01743.20 EJS43939.1 - 1.3e-33 116.1 0.0 2.5e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EJS43939.1 - 2.4e-05 24.0 0.0 6.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EJS43939.1 - 0.0037 17.2 0.1 0.014 15.4 0.0 2.0 3 0 0 3 3 3 1 tRNA nucleotidyltransferase domain 2 putative Ldi PF18566.1 EJS43939.1 - 0.044 13.3 0.0 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 Linalool dehydratase/isomerase JmjC PF02373.22 EJS43940.1 - 3.1e-42 143.6 2.5 7.3e-42 142.4 0.8 2.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 EJS43940.1 - 5.9e-14 51.7 3.3 1e-13 51.0 1.9 2.2 2 0 0 2 2 2 1 jmjN domain zf-H2C2_2 PF13465.6 EJS43940.1 - 1.6e-06 28.3 6.7 1.6e-06 28.3 6.7 3.0 3 0 0 3 3 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EJS43940.1 - 5.5e-06 26.5 16.0 0.0083 16.5 2.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJS43940.1 - 6.4e-05 23.5 15.6 0.076 13.9 5.7 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EJS43940.1 - 0.0019 18.3 3.3 0.0057 16.7 3.3 1.8 1 0 0 1 1 1 1 Zinc ribbon domain zf-C2H2_6 PF13912.6 EJS43940.1 - 0.01 15.8 13.8 0.017 15.1 5.3 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-MYST PF17772.1 EJS43940.1 - 0.069 12.8 0.1 0.21 11.2 0.1 1.8 1 0 0 1 1 1 0 MYST family zinc finger domain DZR PF12773.7 EJS43940.1 - 0.1 12.6 0.5 0.34 10.9 0.5 1.9 1 0 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 EJS43940.1 - 0.44 10.2 3.5 8.9 6.0 0.3 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 EJS43940.1 - 0.87 10.1 7.5 12 6.5 0.5 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EJS43940.1 - 6.4 6.6 8.9 0.91 9.3 3.9 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type DEAD_2 PF06733.15 EJS43941.1 - 6.8e-58 195.2 4.4 1.4e-57 194.1 4.4 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EJS43941.1 - 1.1e-44 152.4 3.1 1.7e-40 138.7 1.0 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EJS43941.1 - 1.6e-44 152.1 0.1 5.5e-44 150.3 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 EJS43941.1 - 0.00069 19.7 0.1 0.0094 16.0 0.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EJS43941.1 - 0.013 15.3 0.0 3.1 7.5 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase Sec63 PF02889.16 EJS43942.1 - 2.3e-137 456.3 2.8 2.4e-78 262.8 0.1 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EJS43942.1 - 2.9e-48 163.9 0.0 6.1e-29 101.0 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EJS43942.1 - 1.1e-18 67.8 2.3 1.5e-13 51.1 0.0 3.2 4 0 0 4 4 3 2 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 EJS43942.1 - 1.9e-18 66.6 0.0 7.6e-18 64.7 0.0 2.2 1 0 0 1 1 1 1 N-terminal helicase PWI domain Helicase_C PF00271.31 EJS43942.1 - 2.6e-09 37.4 0.0 3.5e-07 30.6 0.0 3.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EJS43942.1 - 3.5e-07 30.6 0.9 0.005 17.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 EJS43942.1 - 0.0088 15.5 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_16 PF13191.6 EJS43942.1 - 0.011 16.1 0.0 0.94 9.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 EJS43942.1 - 0.022 14.0 0.0 0.17 11.2 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin T2SSE PF00437.20 EJS43942.1 - 0.042 12.9 0.0 5.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 EJS43942.1 - 0.097 12.2 0.0 12 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg296 PF09644.10 EJS43942.1 - 1.5 9.0 5.5 8.5 6.5 0.1 3.9 3 0 0 3 3 3 0 Mg296 protein Rad17 PF03215.15 EJS43943.1 - 4.2e-64 215.9 3.9 5.9e-64 215.4 0.1 2.7 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 EJS43943.1 - 0.00021 21.7 0.0 0.00049 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EJS43943.1 - 0.0003 20.7 0.0 0.00083 19.3 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 EJS43943.1 - 0.0019 18.5 0.0 0.007 16.7 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 EJS43943.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EJS43943.1 - 0.0086 15.8 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EJS43943.1 - 0.035 13.5 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 EJS43943.1 - 0.093 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EJS43943.1 - 0.12 12.9 0.0 0.5 10.9 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EJS43943.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glutaredoxin PF00462.24 EJS43944.1 - 4.8e-20 71.5 0.0 3.5e-17 62.4 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 EJS43944.1 - 4.5e-15 55.5 0.1 1.2e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 EJS43944.1 - 3.4e-05 23.7 0.0 8.2e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EJS43944.1 - 0.00034 20.9 0.9 0.0025 18.1 0.0 2.6 3 1 1 4 4 4 1 Thioredoxin-like TraF PF13728.6 EJS43944.1 - 0.00072 19.4 0.1 0.08 12.8 0.1 2.1 1 1 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EJS43944.1 - 0.00095 19.6 0.3 0.0055 17.1 0.1 2.3 2 2 1 3 3 3 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EJS43944.1 - 0.00099 18.5 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DIM1 PF02966.16 EJS43944.1 - 0.0018 18.0 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_6 PF13848.6 EJS43944.1 - 0.0064 16.4 0.2 0.018 15.0 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 EJS43944.1 - 0.02 14.9 0.3 0.25 11.3 0.0 2.6 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 EJS43944.1 - 0.034 13.9 0.1 3.4 7.4 0.0 2.2 1 1 1 2 2 2 0 Redoxin SH3BGR PF04908.15 EJS43944.1 - 0.083 13.1 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Drf_DAD PF06345.11 EJS43944.1 - 0.37 10.9 1.3 0.75 10.0 1.3 1.5 1 0 0 1 1 1 0 DRF Autoregulatory Domain Methyltransf_31 PF13847.6 EJS43945.1 - 8.2e-13 48.4 0.0 1.4e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS43945.1 - 4.9e-11 43.2 0.0 8.9e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJS43945.1 - 1.5e-09 38.5 0.0 3.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJS43945.1 - 3.1e-09 37.3 0.0 7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJS43945.1 - 3.1e-06 27.1 0.2 9.7e-06 25.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EJS43945.1 - 0.00015 21.2 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EJS43945.1 - 0.00049 19.5 0.0 0.001 18.5 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EJS43945.1 - 0.00063 19.2 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 EJS43945.1 - 0.01 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EJS43945.1 - 0.035 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 EJS43945.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AAA_12 PF13087.6 EJS43946.1 - 3.9e-61 206.2 0.1 1e-60 204.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EJS43946.1 - 4.2e-33 115.2 0.9 8.6e-18 65.0 0.1 4.3 2 2 1 3 3 3 2 AAA domain AAA_19 PF13245.6 EJS43946.1 - 1.8e-11 44.6 0.0 6.7e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EJS43946.1 - 3e-10 40.1 0.0 5.2e-09 36.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EJS43946.1 - 5.6e-07 29.5 1.1 0.013 15.2 0.0 3.9 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EJS43946.1 - 0.0037 17.1 0.0 0.0094 15.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 EJS43946.1 - 0.01 15.3 0.0 0.082 12.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 EJS43946.1 - 0.013 16.0 0.1 0.08 13.4 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EJS43946.1 - 0.022 15.1 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EJS43946.1 - 0.09 13.1 0.0 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain 14-3-3 PF00244.20 EJS43947.1 - 9.9e-106 352.2 6.3 1.4e-105 351.8 6.3 1.2 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 EJS43947.1 - 0.0089 16.0 1.1 0.025 14.6 1.1 1.7 1 0 0 1 1 1 1 Flagellar protein FlaF SUIM_assoc PF16619.5 EJS43947.1 - 0.014 15.4 1.3 0.014 15.4 1.3 2.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 FRG PF08867.11 EJS43947.1 - 0.49 11.4 0.2 0.49 11.4 0.2 2.4 3 1 1 4 4 4 0 FRG domain MCM6_C PF18263.1 EJS43947.1 - 2.4 8.4 12.0 1.3 9.3 0.8 3.2 3 0 0 3 3 3 0 MCM6 C-terminal winged-helix domain E1_dh PF00676.20 EJS43948.1 - 2.4e-123 410.9 0.0 3e-123 410.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EJS43948.1 - 0.0059 15.8 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.6 EJS43948.1 - 0.018 16.0 3.5 0.34 11.9 0.1 3.3 2 2 0 2 2 2 0 KRTAP type 7 family SPT2 PF08243.11 EJS43950.1 - 1.8e-29 102.5 30.4 1.8e-29 102.5 30.4 1.9 2 0 0 2 2 2 1 SPT2 chromatin protein SNF2_N PF00176.23 EJS43951.1 - 5.6e-62 209.5 0.0 9.6e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cdh1_DBD_1 PF18196.1 EJS43951.1 - 2.3e-43 147.3 2.5 2.3e-43 147.3 2.5 3.7 3 0 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 EJS43951.1 - 3.4e-29 101.1 2.1 3.4e-29 101.1 2.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.24 EJS43951.1 - 1.2e-23 82.7 2.7 2.6e-15 56.0 0.1 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EJS43951.1 - 2.6e-20 72.8 0.0 2.7e-19 69.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS43951.1 - 2.5e-08 34.1 0.0 1.4e-07 31.6 0.0 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 EJS43951.1 - 1.5e-05 25.0 0.1 7.1e-05 22.9 0.1 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJS43951.1 - 7.9e-05 22.8 0.0 0.00041 20.5 0.0 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 EJS43951.1 - 0.0012 18.8 0.0 0.0012 18.8 0.0 3.6 4 0 0 4 4 4 1 SLIDE CHDCT2 PF08074.11 EJS43951.1 - 0.0022 18.2 0.0 0.014 15.6 0.0 2.4 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain CDH1_2_SANT_HL1 PF18375.1 EJS43951.1 - 0.76 10.5 5.2 0.74 10.5 0.4 3.3 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 Aminotran_1_2 PF00155.21 EJS43952.1 - 5.1e-20 72.0 0.0 6e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EJS43952.1 - 5.6e-05 22.1 0.0 9.2e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase 60KD_IMP PF02096.20 EJS43953.1 - 2e-22 79.8 0.4 2e-22 79.8 0.4 2.1 2 0 0 2 2 2 1 60Kd inner membrane protein DUF3899 PF13038.6 EJS43953.1 - 1.9 9.0 4.3 1.8 9.1 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) DUF2780 PF11075.8 EJS43953.1 - 6.3 6.9 8.8 0.31 11.2 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) UPF0160 PF03690.13 EJS43954.1 - 2.5e-127 424.9 0.0 2.8e-127 424.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) GDI PF00996.18 EJS43956.1 - 5.6e-232 769.8 0.2 6.5e-232 769.6 0.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EJS43956.1 - 0.0018 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-C2H2_10 PF16588.5 EJS43957.1 - 4.5e-12 45.5 4.5 6.7e-12 44.9 4.5 1.3 1 0 0 1 1 1 1 C2H2 zinc-finger eIF3g PF12353.8 EJS43957.1 - 0.065 13.6 1.3 0.19 12.1 0.3 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G DUF747 PF05346.11 EJS43958.1 - 8.4e-84 281.7 19.8 1.3e-83 281.1 19.8 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family COX15-CtaA PF02628.15 EJS43959.1 - 4.4e-114 380.9 6.4 5.4e-114 380.6 6.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Cytochrom_B561 PF03188.16 EJS43959.1 - 0.0084 16.3 2.1 0.0084 16.3 2.1 2.0 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 HhH-GPD PF00730.25 EJS43960.1 - 7.1e-13 48.9 0.0 1.6e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Asp_protease PF09668.10 EJS43961.1 - 3.8e-50 168.8 0.2 5.8e-50 168.2 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EJS43961.1 - 1.1e-17 64.4 0.1 2e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.31 EJS43961.1 - 1.6e-09 37.4 0.0 4.8e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Asp_protease_2 PF13650.6 EJS43961.1 - 4.3e-08 33.7 0.6 8.3e-08 32.8 0.2 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.20 EJS43961.1 - 0.00012 22.3 0.1 0.00026 21.3 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 EJS43961.1 - 0.0024 17.7 0.0 0.0061 16.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.8 EJS43961.1 - 0.012 16.1 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 UBA_3 PF09288.10 EJS43961.1 - 0.12 12.2 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain UCH PF00443.29 EJS43962.1 - 5.8e-60 203.0 1.3 9.1e-60 202.3 1.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJS43962.1 - 6.1e-23 81.9 2.5 7.5e-22 78.3 2.5 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EJS43962.1 - 9.6e-08 32.5 0.0 2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain FTR1 PF03239.14 EJS43963.1 - 8.4e-107 356.9 7.2 1e-106 356.6 7.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF839 PF05787.13 EJS43963.1 - 0.033 13.3 0.1 0.046 12.9 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) LSM PF01423.22 EJS43964.1 - 1.1e-19 69.9 0.3 1.3e-19 69.7 0.3 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 EJS43964.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain TBP PF00352.21 EJS43965.1 - 8e-68 224.4 0.1 1.1e-32 111.8 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EJS43965.1 - 2.6e-05 24.2 0.1 0.35 11.0 0.0 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EJS43965.1 - 0.063 13.1 0.1 0.51 10.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) CALCOCO1 PF07888.11 EJS43966.1 - 0.0013 17.7 3.5 0.0013 17.7 3.5 1.8 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like NYD-SP28_assoc PF14775.6 EJS43966.1 - 0.028 14.5 3.2 0.043 13.9 1.0 2.5 1 1 1 2 2 2 0 Sperm tail C-terminal domain Fmp27_WPPW PF10359.9 EJS43966.1 - 0.033 13.0 5.7 0.011 14.6 3.0 1.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain ADIP PF11559.8 EJS43966.1 - 0.16 12.1 12.3 0.092 12.8 7.0 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Nup54 PF13874.6 EJS43966.1 - 0.27 11.3 2.6 0.72 10.0 2.6 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4337 PF14235.6 EJS43966.1 - 0.37 10.9 1.6 1 9.4 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CENP-F_leu_zip PF10473.9 EJS43966.1 - 3.2 7.8 15.1 0.4 10.7 7.6 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.11 EJS43966.1 - 5 7.7 12.1 0.72 10.4 3.9 3.2 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Cnn_1N PF07989.11 EJS43966.1 - 8.6 6.6 17.7 0.12 12.6 8.9 2.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 zf-RING_4 PF14570.6 EJS43968.1 - 1.9e-20 72.3 13.5 3.6e-20 71.5 13.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EJS43968.1 - 2.6e-07 30.4 7.8 5.3e-07 29.4 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 EJS43968.1 - 5.2e-06 26.2 0.1 8.9e-05 22.2 0.1 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.12 EJS43968.1 - 8.8e-06 25.3 1.2 8.8e-06 25.3 1.2 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger Baculo_IE-1 PF05290.11 EJS43968.1 - 5.2e-05 23.2 3.0 0.00011 22.1 3.0 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 EJS43968.1 - 0.00074 19.8 10.1 0.0015 18.9 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EJS43968.1 - 0.005 16.7 8.7 0.13 12.2 9.6 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 SET_assoc PF11767.8 EJS43968.1 - 0.0065 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated zf-C3HC4 PF00097.25 EJS43968.1 - 0.0089 15.9 10.9 0.019 14.8 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 EJS43968.1 - 0.13 12.3 5.3 0.3 11.2 5.3 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger PocR PF10114.9 EJS43968.1 - 0.22 11.3 3.5 0.35 10.6 1.8 2.1 2 0 0 2 2 2 0 Sensory domain found in PocR zf-RING_5 PF14634.6 EJS43968.1 - 0.25 11.4 9.7 0.52 10.3 9.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EJS43968.1 - 2.1 8.4 8.9 3.2 7.8 8.0 1.8 1 1 0 1 1 1 0 RING-type zinc-finger Ribonuc_red_lgC PF02867.15 EJS43969.1 - 3.3e-184 613.3 0.0 4.4e-184 612.9 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EJS43969.1 - 1.9e-23 82.3 0.0 5.4e-23 80.8 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EJS43969.1 - 2.1e-16 60.3 0.0 6.4e-16 58.7 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Tctex-1 PF03645.13 EJS43970.1 - 2e-06 28.0 0.1 2.5e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family DRE2_N PF16803.5 EJS43970.1 - 0.1 12.8 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus DUF202 PF02656.15 EJS43971.1 - 2.4e-14 53.5 4.4 3.3e-14 53.1 3.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 EJS43971.1 - 0.33 10.8 2.8 0.86 9.5 2.8 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5337) Aldedh PF00171.22 EJS43972.1 - 1.4e-183 610.6 0.7 1.6e-183 610.5 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Beta_lactamase3 PF17030.5 EJS43972.1 - 0.061 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative beta-lactamase-like family Y_phosphatase PF00102.27 EJS43973.1 - 1.7e-47 162.0 0.1 5.4e-47 160.3 0.1 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EJS43973.1 - 9.3e-09 35.8 0.0 3.4e-08 34.0 0.0 2.1 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 EJS43973.1 - 0.0037 17.1 0.1 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EJS43973.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Peptidase_M24 PF00557.24 EJS43974.1 - 5.7e-52 176.4 0.0 8.5e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EJS43974.1 - 6.7e-37 126.0 0.0 1.4e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain FAM220 PF15487.6 EJS43975.1 - 0.05 13.2 6.3 0.073 12.7 6.3 1.3 1 0 0 1 1 1 0 FAM220 family APH PF01636.23 EJS43976.1 - 2.5e-07 30.9 0.0 1.7e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EJS43976.1 - 0.0031 16.9 0.0 3.2 7.1 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family LidA_Long_CC PF18641.1 EJS43976.1 - 0.0043 17.1 0.4 0.012 15.6 0.4 1.8 1 0 0 1 1 1 1 LidA long coiled-coil domain Choline_kinase PF01633.20 EJS43976.1 - 0.0061 16.2 0.1 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase 2-Hacid_dh_C PF02826.19 EJS43977.1 - 1.3e-53 181.0 0.0 2.2e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EJS43977.1 - 7.5e-40 135.7 0.1 1e-39 135.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EJS43977.1 - 1.6e-05 25.1 1.3 4.7e-05 23.6 0.2 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EJS43977.1 - 0.00013 22.1 0.1 0.00028 21.0 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 EJS43977.1 - 0.038 13.8 0.0 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 ACT domain XdhC_C PF13478.6 EJS43977.1 - 0.069 13.7 0.1 0.27 11.8 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Acetyltransf_1 PF00583.25 EJS43977.1 - 0.073 13.3 0.0 0.22 11.7 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4367 PF14285.6 EJS43977.1 - 0.17 12.3 0.8 0.39 11.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) BING4CT PF08149.11 EJS43978.1 - 4.9e-38 128.8 0.1 5.3e-35 119.1 0.0 4.0 4 0 0 4 4 4 1 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EJS43978.1 - 3.3e-05 24.1 0.1 3 8.2 0.0 5.0 3 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJS43978.1 - 0.00011 22.9 0.2 0.077 13.9 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat GET2 PF08690.10 EJS43979.1 - 1.5e-89 300.7 2.1 1e-63 215.9 0.0 2.0 1 1 1 2 2 2 2 GET complex subunit GET2 PALP PF00291.25 EJS43980.1 - 2.7e-78 263.4 0.2 3.8e-78 262.9 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EJS43980.1 - 1.8e-42 143.0 0.0 1.4e-28 98.5 0.0 2.7 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase tRNA-synt_2b PF00587.25 EJS43981.1 - 9.7e-36 123.4 0.0 1.5e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Sec61_beta PF03911.16 EJS43982.1 - 1.9e-16 59.8 0.9 2.3e-16 59.5 0.9 1.1 1 0 0 1 1 1 1 Sec61beta family Myb_DNA-binding PF00249.31 EJS43983.1 - 1.4e-12 47.5 0.3 1.4e-11 44.4 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJS43983.1 - 4.8e-09 36.3 1.3 9.5e-09 35.4 0.3 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Chorismate_bind PF00425.18 EJS43984.1 - 1.6e-89 299.9 0.0 3e-88 295.7 0.0 2.1 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EJS43984.1 - 8.8e-31 107.0 0.0 1.4e-28 99.9 0.0 3.2 2 1 1 3 3 3 1 Anthranilate synthase component I, N terminal region POR PF01558.18 EJS43984.1 - 0.042 13.9 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Meth_synt_2 PF01717.18 EJS43985.1 - 1.9e-154 513.8 0.0 1.7e-150 500.8 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EJS43985.1 - 8e-124 413.2 0.0 1.5e-115 386.0 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain IES5 PF17335.2 EJS43986.1 - 3.1e-46 156.3 1.9 3.5e-46 156.2 1.9 1.0 1 0 0 1 1 1 1 Ino80 complex subunit 5 RICTOR_N PF14664.6 EJS43987.1 - 2.7e-99 332.7 10.1 6e-99 331.5 10.1 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EJS43987.1 - 4.4e-31 106.7 5.5 1.7e-28 98.5 0.1 5.7 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 EJS43987.1 - 9.9e-31 105.8 0.4 2.4e-29 101.4 0.2 3.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 EJS43987.1 - 1.7e-29 102.3 5.9 2.8e-28 98.4 0.2 4.2 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Enkurin PF13864.6 EJS43987.1 - 0.29 11.6 6.4 1.8 9.1 0.2 3.6 2 2 1 3 3 3 0 Calmodulin-binding Proteasome PF00227.26 EJS43988.1 - 1.2e-41 142.3 0.0 1.5e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Rad51 PF08423.11 EJS43989.1 - 4.2e-127 422.7 0.0 5.2e-127 422.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EJS43989.1 - 1.4e-12 47.7 0.1 2.8e-12 46.7 0.0 1.5 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EJS43989.1 - 1.7e-09 37.5 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 EJS43989.1 - 4.1e-08 33.7 0.3 8.4e-08 32.7 0.3 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 EJS43989.1 - 6.8e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EJS43989.1 - 0.0063 15.9 0.0 0.026 13.9 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 EJS43989.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sel1 PF08238.12 EJS43990.1 - 9.8e-18 64.2 4.5 0.00025 21.6 0.1 4.7 4 0 0 4 4 4 4 Sel1 repeat TPR_11 PF13414.6 EJS43990.1 - 0.27 10.9 2.0 25 4.7 0.1 3.6 4 0 0 4 4 4 0 TPR repeat UCH PF00443.29 EJS43991.1 - 3.1e-70 236.6 8.2 1.1e-69 234.8 8.2 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJS43991.1 - 4.9e-18 65.8 28.4 4.3e-16 59.4 9.0 4.1 4 1 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase Pribosyltran_N PF13793.6 EJS43992.1 - 6.4e-43 145.4 0.1 8.3e-41 138.6 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EJS43992.1 - 4.6e-36 124.6 2.0 2.9e-29 102.4 0.8 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EJS43992.1 - 2.2e-15 56.5 0.5 9.2e-15 54.5 0.3 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EJS43992.1 - 0.0035 16.8 0.1 0.0053 16.2 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UQ_con PF00179.26 EJS43993.1 - 8.6e-22 77.3 0.1 1.3e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EJS43993.1 - 0.13 12.5 0.7 0.26 11.6 0.1 1.7 1 1 0 1 1 1 0 RWD domain ADH_zinc_N_2 PF13602.6 EJS43994.1 - 2.1e-14 54.7 0.0 5.1e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJS43994.1 - 4.9e-05 23.2 0.0 9.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3786 PF12654.7 EJS43994.1 - 0.0034 17.0 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3786) ADH_zinc_N PF00107.26 EJS43994.1 - 0.082 12.9 0.0 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Ribosomal_S8e PF01201.22 EJS43995.1 - 4.7e-57 192.0 2.3 6e-57 191.6 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e HSP70 PF00012.20 EJS43996.1 - 8.8e-260 863.0 8.4 1e-259 862.8 8.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJS43996.1 - 3.4e-17 62.3 0.0 4.1e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EJS43996.1 - 0.0005 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EJS43996.1 - 0.011 15.0 0.1 0.032 13.5 0.1 1.9 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EJS43996.1 - 0.034 13.7 0.0 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 EJS43996.1 - 0.072 12.1 0.1 1.2 8.1 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Golgin_A5 PF09787.9 EJS43996.1 - 1.9 7.9 7.0 1.6 8.1 3.5 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 WD40 PF00400.32 EJS43997.1 - 7e-17 61.5 5.8 0.00013 22.6 0.3 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS43997.1 - 7.3e-07 29.4 0.0 0.27 11.5 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJS43997.1 - 0.0021 16.8 0.0 1.4 7.4 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 LisH PF08513.11 EJS43998.1 - 0.0019 18.1 0.1 0.0031 17.4 0.1 1.4 1 0 0 1 1 1 1 LisH DUF3408 PF11888.8 EJS43998.1 - 0.28 11.3 4.2 1.4 9.0 4.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) IBN_N PF03810.19 EJS43999.1 - 5.5e-17 61.4 3.8 9.7e-14 51.1 0.2 4.1 3 0 0 3 3 3 2 Importin-beta N-terminal domain HEAT_EZ PF13513.6 EJS43999.1 - 4.5e-15 55.8 0.0 0.0049 17.3 0.0 7.9 8 0 0 8 8 7 2 HEAT-like repeat HEAT PF02985.22 EJS43999.1 - 2.5e-11 42.8 0.7 0.21 11.9 0.0 8.0 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 EJS43999.1 - 5.1e-10 39.6 0.3 0.012 16.0 0.0 6.1 5 0 0 5 5 5 2 HEAT repeats RIX1 PF08167.12 EJS43999.1 - 2.2e-05 24.3 0.0 0.081 12.7 0.0 4.7 3 2 1 4 4 4 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 EJS43999.1 - 4.7e-05 23.5 7.6 1.4 8.9 0.6 5.5 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EJS43999.1 - 0.00016 22.2 2.5 34 5.1 0.0 6.5 5 1 2 8 8 7 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EJS43999.1 - 0.00021 20.9 0.7 5 6.6 0.0 4.8 5 1 0 5 5 5 2 CLASP N terminal G-alpha PF00503.20 EJS43999.1 - 0.013 14.7 0.1 0.029 13.5 0.1 1.6 1 0 0 1 1 1 0 G-protein alpha subunit RTP1_C1 PF10363.9 EJS43999.1 - 0.092 12.9 0.6 4.1 7.6 0.1 3.7 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HHV-5_US34A PF17087.5 EJS43999.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus US34A protein family Ank_2 PF12796.7 EJS44000.1 - 2.4e-07 31.2 1.4 0.014 16.0 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJS44000.1 - 8.5e-07 29.4 1.7 0.075 13.6 0.3 3.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EJS44000.1 - 3.8e-06 26.7 3.3 3.8e-06 26.7 3.3 4.3 3 2 0 3 3 3 1 KilA-N domain Ank PF00023.30 EJS44000.1 - 0.00029 21.2 1.9 0.4 11.2 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EJS44000.1 - 0.00057 20.1 1.5 0.1 13.2 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EJS44000.1 - 0.058 13.7 0.3 0.058 13.7 0.3 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) LSM PF01423.22 EJS44001.1 - 4.9e-18 64.6 1.1 8.3e-18 63.8 1.1 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EJS44001.1 - 2.1e-06 27.8 0.3 5.3e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.7 EJS44001.1 - 0.065 13.4 0.3 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain ALMT PF11744.8 EJS44001.1 - 3.8 6.2 7.2 4.1 6.1 7.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PH PF00169.29 EJS44002.1 - 1.1e-18 67.7 0.0 1.1e-18 67.7 0.0 2.7 3 0 0 3 3 3 1 PH domain SH3_1 PF00018.28 EJS44002.1 - 4.4e-14 51.8 0.2 9.5e-14 50.7 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 EJS44002.1 - 5.7e-12 45.6 0.1 1.2e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 EJS44002.1 - 3.1e-06 26.9 0.1 6.5e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.6 EJS44002.1 - 3.6e-05 23.9 0.0 0.0055 17.0 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.30 EJS44002.1 - 0.00075 19.9 0.1 0.0014 19.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 EJS44002.1 - 0.008 16.6 0.0 0.008 16.6 0.0 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain SH3_2 PF07653.17 EJS44002.1 - 0.023 14.3 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain zf-C3HC4 PF00097.25 EJS44004.1 - 4.5e-07 29.6 14.4 8.1e-07 28.8 14.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJS44004.1 - 7.2e-06 25.8 9.1 7.2e-06 25.8 9.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJS44004.1 - 1e-05 25.3 12.0 1.9e-05 24.4 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJS44004.1 - 6.8e-05 23.1 14.8 0.00011 22.4 14.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EJS44004.1 - 0.00012 22.0 12.2 0.00023 21.1 12.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EJS44004.1 - 0.001 19.0 13.6 0.0029 17.5 13.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EJS44004.1 - 0.26 11.5 14.9 0.49 10.6 14.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EJS44004.1 - 0.71 9.8 14.0 3.3 7.7 14.5 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SH3_1 PF00018.28 EJS44005.1 - 2.1e-12 46.5 0.2 3.7e-12 45.7 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJS44005.1 - 6.5e-11 41.9 0.1 1.1e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJS44005.1 - 3.7e-07 29.7 0.0 7.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TctB PF07331.11 EJS44005.1 - 0.0072 16.6 1.9 0.011 16.1 1.9 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family Aa_trans PF01490.18 EJS44006.1 - 5.9e-119 397.4 29.6 6.7e-119 397.2 29.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EJS44006.1 - 1.3e-10 40.9 16.5 1.3e-10 40.9 16.5 1.9 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family Motile_Sperm PF00635.26 EJS44007.1 - 9.5e-27 93.0 0.6 1.8e-26 92.1 0.0 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 EJS44007.1 - 7.1e-05 23.0 0.1 0.00017 21.8 0.1 1.6 1 0 0 1 1 1 1 Transmembrane protein 131-like DUF5001 PF16392.5 EJS44007.1 - 0.021 14.7 0.2 0.082 12.8 0.0 2.0 2 0 0 2 2 2 0 Ig-like domain Big_2 PF02368.18 EJS44007.1 - 0.03 14.2 0.6 1.7 8.6 0.4 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) ArfGap PF01412.18 EJS44008.1 - 9.7e-34 115.9 0.7 9.7e-34 115.9 0.7 2.5 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf TFIID_NTD2 PF04494.15 EJS44008.1 - 6 7.1 7.3 3.2 8.0 1.8 3.1 3 0 0 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain Pkinase PF00069.25 EJS44009.1 - 2e-17 63.4 0.0 1.6e-16 60.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44009.1 - 5.6e-07 29.1 0.0 9.8e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJS44009.1 - 9.8e-06 24.6 0.0 9.8e-06 24.6 0.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase KHA PF11834.8 EJS44009.1 - 0.18 11.9 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel HECT PF00632.25 EJS44011.1 - 1e-94 317.5 0.0 1.4e-94 317.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EJS44011.1 - 4.3e-34 116.3 22.8 4.2e-12 45.9 1.3 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 EJS44011.1 - 1.5e-19 70.2 0.1 4.2e-19 68.7 0.1 1.8 1 0 0 1 1 1 1 C2 domain Macoilin PF09726.9 EJS44011.1 - 2.1 6.8 4.6 2.7 6.4 4.6 1.2 1 0 0 1 1 1 0 Macoilin family Ribosomal_S8e PF01201.22 EJS44012.1 - 6.7e-45 152.6 0.1 1.1e-44 152.0 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e Sas10_Utp3 PF04000.15 EJS44013.1 - 1.6e-10 41.5 0.4 1.6e-10 41.5 0.4 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Imm5 PF14423.6 EJS44013.1 - 0.18 12.0 1.8 0.45 10.7 0.1 2.1 2 0 0 2 2 2 0 Immunity protein Imm5 FERM_M PF00373.18 EJS44013.1 - 1.7 9.0 4.9 3 8.3 4.9 1.6 1 1 0 1 1 1 0 FERM central domain zf-C2H2 PF00096.26 EJS44014.1 - 6.3e-10 39.0 19.9 7.3e-06 26.2 3.4 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJS44014.1 - 1.9e-09 37.5 11.8 9.2e-05 23.0 1.5 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EJS44014.1 - 1.6e-05 25.1 10.3 0.021 15.2 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EJS44014.1 - 1.7e-05 25.0 8.7 0.0016 18.7 1.6 3.5 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EJS44014.1 - 0.0015 18.8 17.9 0.0019 18.6 6.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EJS44014.1 - 0.0025 17.7 1.4 0.0025 17.7 1.4 3.4 4 0 0 4 4 4 1 C2H2-type zinc finger zf-Di19 PF05605.12 EJS44014.1 - 0.025 14.8 7.1 0.044 14.1 7.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 EJS44014.1 - 0.086 12.7 1.1 0.21 11.4 1.1 1.7 1 0 0 1 1 1 0 GAGA factor zf-BED PF02892.15 EJS44014.1 - 0.14 12.2 9.9 0.59 10.2 6.9 2.9 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.7 EJS44014.1 - 0.28 11.6 7.9 6 7.3 1.1 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.13 EJS44014.1 - 0.57 10.3 8.8 1.9 8.6 2.9 2.5 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-H2C2_5 PF13909.6 EJS44014.1 - 2.9 7.7 11.9 3.7 7.4 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 EJS44014.1 - 3.5 8.2 10.0 98 3.5 10.0 2.8 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 EJS44014.1 - 5.3 7.1 8.9 10 6.2 2.8 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Ribosomal_S26e PF01283.19 EJS44015.1 - 3e-51 172.4 9.8 3.5e-51 172.2 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e ICL PF00463.21 EJS44016.1 - 1.6e-300 997.1 0.3 1.8e-300 996.9 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EJS44016.1 - 4.4e-09 36.1 0.0 8e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase HisG PF01634.18 EJS44017.1 - 6.5e-52 175.7 0.5 8.5e-52 175.3 0.5 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EJS44017.1 - 7.4e-27 93.3 0.0 1.3e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain Transp_cyt_pur PF02133.15 EJS44018.1 - 3.6e-117 391.8 40.4 4.2e-117 391.6 40.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ribonuc_L-PSP PF01042.21 EJS44019.1 - 1.2e-42 144.7 1.1 1.4e-42 144.6 1.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PET117 PF15786.5 EJS44020.1 - 7.6e-33 112.6 0.9 1e-32 112.2 0.9 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Phage_cap_E PF03864.15 EJS44020.1 - 0.072 12.3 0.4 0.076 12.2 0.4 1.0 1 0 0 1 1 1 0 Phage major capsid protein E Cyclin PF08613.11 EJS44021.1 - 1.5e-47 162.0 0.2 4e-26 92.3 0.0 2.5 2 0 0 2 2 2 2 Cyclin HAD_2 PF13419.6 EJS44022.1 - 1.7e-15 57.5 0.0 2.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJS44022.1 - 1.7e-12 48.1 0.0 2e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EJS44022.1 - 0.0018 18.7 0.0 0.0031 18.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJS44022.1 - 0.0067 16.5 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Tho1_MOS11_C PF18592.1 EJS44023.1 - 1.2e-25 89.0 0.7 2.4e-25 88.1 0.7 1.5 1 0 0 1 1 1 1 Tho1/MOS11 C-terminal domain SAP PF02037.27 EJS44023.1 - 2.7e-12 46.1 0.6 4.6e-12 45.4 0.6 1.4 1 0 0 1 1 1 1 SAP domain DDOST_48kD PF03345.14 EJS44024.1 - 2.9e-122 408.5 0.4 3.3e-122 408.3 0.4 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Phage_holin_3_3 PF16083.5 EJS44025.1 - 0.095 12.8 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III Nop16 PF09420.10 EJS44026.1 - 1.3e-70 237.7 11.0 1.6e-70 237.4 11.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 HIM1 PF08732.10 EJS44027.1 - 1.6e-09 37.5 0.0 6.7e-09 35.5 0.0 1.8 1 1 1 2 2 2 1 HIM1 NAD_binding_10 PF13460.6 EJS44027.1 - 2.2e-06 27.7 0.0 3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EJS44027.1 - 0.00011 21.8 0.0 0.00062 19.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EJS44027.1 - 0.033 13.8 0.0 0.06 12.9 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.24 EJS44027.1 - 0.11 12.9 0.0 0.5 10.8 0.0 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDA1_CD39 PF01150.17 EJS44028.1 - 8.3e-168 558.4 0.0 4.3e-167 556.1 0.0 1.8 2 0 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family GN3L_Grn1 PF08701.11 EJS44029.1 - 6.8e-22 77.4 19.2 2.5e-21 75.6 19.2 2.0 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EJS44029.1 - 8.5e-19 67.7 0.0 4.6e-14 52.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EJS44029.1 - 2.4e-07 30.4 0.0 3.9e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EJS44029.1 - 2.4e-05 23.8 0.0 0.00013 21.3 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 EJS44029.1 - 3.3e-05 24.0 4.2 0.11 12.5 0.1 3.9 2 2 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EJS44029.1 - 5.7e-05 23.1 0.1 0.0022 17.9 0.1 2.4 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 EJS44029.1 - 0.00014 21.5 0.0 0.15 11.6 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 EJS44029.1 - 0.0033 17.0 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EJS44029.1 - 0.019 15.5 0.0 0.069 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EJS44029.1 - 0.039 12.9 1.2 0.059 12.3 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM6_C PF18263.1 EJS44029.1 - 0.043 14.1 0.4 0.12 12.6 0.2 1.9 1 1 0 1 1 1 0 MCM6 C-terminal winged-helix domain NTF2 PF02136.20 EJS44030.1 - 1e-36 126.1 0.4 1.2e-36 125.9 0.4 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 EJS44030.1 - 0.00029 20.1 0.5 0.0015 17.7 0.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) DUF4440 PF14534.6 EJS44030.1 - 0.17 12.3 0.0 0.19 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) RraA-like PF03737.15 EJS44031.1 - 2.4e-31 108.9 0.0 2.9e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA SRP1_TIP1 PF00660.17 EJS44032.1 - 1.4e-37 127.7 0.5 2.9e-37 126.7 0.5 1.5 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.19 EJS44032.1 - 5.3e-07 29.0 7.3 5.3e-07 29.0 7.3 2.4 2 0 0 2 2 2 1 Yeast PIR protein repeat Spc42p PF11544.8 EJS44032.1 - 0.059 13.4 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p SLD3 PF08639.10 EJS44032.1 - 0.075 11.8 12.6 0.1 11.3 12.6 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Macoilin PF09726.9 EJS44032.1 - 3 6.3 17.6 5.7 5.4 17.6 1.4 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 EJS44032.1 - 3.6 7.1 9.3 3.9 7.0 9.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hamartin PF04388.12 EJS44032.1 - 4.5 5.8 17.5 5.2 5.6 17.5 1.1 1 0 0 1 1 1 0 Hamartin protein Lin-8 PF03353.15 EJS44032.1 - 6.4 6.2 8.4 9.7 5.6 8.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SOBP PF15279.6 EJS44032.1 - 7.1 7.1 14.7 10 6.6 14.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SRP-alpha_N PF04086.13 EJS44032.1 - 9.1 6.1 14.3 12 5.7 14.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CytochromB561_N PF09786.9 EJS44032.1 - 9.7 5.0 23.0 12 4.8 23.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Proteasome PF00227.26 EJS44033.1 - 1e-43 149.0 0.0 1.2e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit HA2 PF04408.23 EJS44034.1 - 5.7e-22 78.0 0.0 5.7e-22 78.0 0.0 2.6 2 1 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EJS44034.1 - 2.1e-18 66.4 0.0 4.8e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EJS44034.1 - 2.1e-13 50.6 0.2 2.1e-12 47.4 0.0 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain S1 PF00575.23 EJS44034.1 - 9.9e-12 45.0 0.4 3.5e-11 43.3 0.2 2.1 2 0 0 2 2 1 1 S1 RNA binding domain DEAD PF00270.29 EJS44034.1 - 2e-05 24.5 0.3 8.2e-05 22.4 0.3 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EJS44034.1 - 0.00013 22.3 0.0 0.00039 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJS44034.1 - 0.00063 19.5 0.1 0.0012 18.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EJS44034.1 - 0.00066 20.2 1.2 0.38 11.3 0.0 4.1 4 0 0 4 4 3 1 ABC transporter PWI PF01480.17 EJS44034.1 - 0.0016 18.7 0.4 0.2 12.0 0.1 2.7 2 0 0 2 2 2 1 PWI domain T2SSE PF00437.20 EJS44034.1 - 0.0018 17.4 0.1 0.01 14.9 0.0 2.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_7 PF12775.7 EJS44034.1 - 0.031 13.8 0.0 0.091 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EJS44034.1 - 0.042 13.9 0.0 0.57 10.2 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EJS44034.1 - 0.088 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EJS44034.1 - 0.094 12.3 0.1 0.23 11.1 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 EJS44034.1 - 0.79 10.2 0.0 0.79 10.2 0.0 3.6 3 1 0 3 3 2 0 AAA domain Amino_oxidase PF01593.24 EJS44035.1 - 3.8e-14 52.8 0.0 5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EJS44035.1 - 1.9e-13 50.4 0.0 4e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJS44035.1 - 1.2e-05 25.7 1.1 0.008 16.7 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EJS44035.1 - 3.5e-05 23.6 0.7 7.4e-05 22.5 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EJS44035.1 - 0.00011 21.5 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EJS44035.1 - 0.00059 19.2 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJS44035.1 - 0.0023 17.9 0.0 0.0056 16.7 0.0 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.15 EJS44035.1 - 0.14 10.7 0.0 0.26 9.8 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) EB1 PF03271.17 EJS44036.1 - 3.6e-16 59.1 0.1 6.8e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EJS44036.1 - 5e-05 23.4 0.1 9.4e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Tmemb_cc2 PF10267.9 EJS44036.1 - 0.02 14.1 0.1 0.024 13.8 0.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein ATG16 PF08614.11 EJS44036.1 - 0.021 15.1 0.1 0.031 14.5 0.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-C4H2 PF10146.9 EJS44036.1 - 0.045 14.1 0.2 0.088 13.1 0.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein DivIC PF04977.15 EJS44036.1 - 0.084 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Sec61_beta PF03911.16 EJS44037.1 - 3.4e-15 55.8 0.5 4.2e-15 55.5 0.5 1.1 1 0 0 1 1 1 1 Sec61beta family G-alpha PF00503.20 EJS44038.1 - 2e-105 352.8 1.1 2.3e-105 352.6 0.7 1.2 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EJS44038.1 - 1.2e-15 57.4 0.9 2.5e-10 40.1 0.2 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EJS44038.1 - 0.00026 20.4 0.2 0.044 13.1 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EJS44038.1 - 0.00096 19.4 3.1 0.57 10.4 0.1 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EJS44038.1 - 0.054 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EJS44038.1 - 0.065 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EJS44038.1 - 0.086 12.6 0.1 0.58 9.9 0.2 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain CPT PF07931.12 EJS44038.1 - 0.13 12.1 0.1 9 6.1 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein CEND1 PF15677.5 EJS44038.1 - 1.6 9.3 7.0 2.6 8.6 7.0 1.3 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 PCI PF01399.27 EJS44039.1 - 2.6e-20 72.9 0.5 2.6e-20 72.9 0.5 2.4 3 0 0 3 3 3 1 PCI domain Rpn3_C PF08375.11 EJS44039.1 - 3.6e-19 68.9 2.9 3.6e-19 68.9 2.9 2.0 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal HTH_27 PF13463.6 EJS44039.1 - 0.08 13.4 0.1 0.22 12.1 0.1 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain TPR_15 PF13429.6 EJS44039.1 - 0.1 11.8 0.6 12 5.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Med17 PF10156.9 EJS44040.1 - 3.1e-180 599.8 19.8 5.5e-180 599.0 19.8 1.3 1 0 0 1 1 1 1 Subunit 17 of Mediator complex P5CR_dimer PF14748.6 EJS44041.1 - 5.9e-33 113.2 0.4 1e-32 112.4 0.4 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EJS44041.1 - 1.6e-10 41.4 0.2 4.2e-10 40.1 0.2 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Carn_acyltransf PF00755.20 EJS44042.1 - 1.7e-114 383.6 0.0 6.3e-114 381.7 0.0 1.7 2 0 0 2 2 2 1 Choline/Carnitine o-acyltransferase Sorting_nexin PF03700.13 EJS44042.1 - 0.093 13.3 3.5 2.2 8.8 0.1 2.6 2 0 0 2 2 2 0 Sorting nexin, N-terminal domain eIF2_C PF09173.11 EJS44043.1 - 1.1e-34 118.5 0.3 2.8e-34 117.2 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EJS44043.1 - 3.8e-23 82.0 0.1 3.5e-22 78.9 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EJS44043.1 - 2.9e-11 43.6 0.5 2.9e-11 43.6 0.5 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EJS44043.1 - 0.003 17.6 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJS44043.1 - 0.0041 17.0 0.1 0.049 13.5 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EJS44043.1 - 0.037 14.0 0.1 0.089 12.8 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain CDP-OH_P_transf PF01066.21 EJS44044.1 - 4.7e-11 43.3 0.3 4.7e-11 43.3 0.3 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CclA_1 PF16942.5 EJS44044.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative cyclic bacteriocin AMPKBI PF04739.15 EJS44045.1 - 2.9e-29 101.1 2.7 1.3e-28 99.0 2.7 2.2 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 EJS44045.1 - 5.4e-29 100.3 0.0 1.2e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Ras PF00071.22 EJS44046.1 - 8.5e-61 204.3 0.1 1e-60 204.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS44046.1 - 2.2e-34 118.3 0.1 3.5e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS44046.1 - 1.5e-13 50.5 0.0 2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EJS44046.1 - 1.2e-06 28.6 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase KAP_NTPase PF07693.14 EJS44046.1 - 0.00077 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain GTP_EFTU PF00009.27 EJS44046.1 - 0.00084 18.9 0.0 0.0067 16.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EJS44046.1 - 0.0014 18.1 0.0 0.002 17.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EJS44046.1 - 0.0022 17.9 0.1 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EJS44046.1 - 0.012 15.9 0.1 0.057 13.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EJS44046.1 - 0.028 14.1 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EJS44046.1 - 0.029 14.1 0.0 0.042 13.6 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EJS44046.1 - 0.033 14.7 0.3 0.054 14.0 0.3 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EJS44046.1 - 0.039 14.4 0.1 0.059 13.8 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EJS44046.1 - 0.046 13.2 0.1 0.16 11.4 0.0 1.8 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.18 EJS44046.1 - 0.053 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 EJS44046.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 EJS44046.1 - 0.09 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 EJS44046.1 - 0.093 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 EJS44046.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 EJS44046.1 - 0.16 11.8 0.6 0.25 11.1 0.6 1.3 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF5364 PF17322.2 EJS44048.1 - 1.4e-65 221.1 15.1 1.6e-65 220.9 15.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5364) Lipoprotein_22 PF17294.2 EJS44048.1 - 0.027 14.1 1.7 0.045 13.4 1.7 1.5 1 0 0 1 1 1 0 Uncharacterised lipoprotein family USP19_linker PF16602.5 EJS44048.1 - 0.43 11.1 3.4 2.1 8.9 0.9 2.2 2 0 0 2 2 2 0 Linker region of USP19 deubiquitinase PNRC PF15365.6 EJS44049.1 - 0.00055 19.7 0.5 0.00055 19.7 0.5 2.8 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif ABC_tran PF00005.27 EJS44050.1 - 1.5e-49 168.0 0.0 1.6e-24 87.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EJS44050.1 - 1.1e-21 76.7 1.8 1.1e-21 76.7 1.8 2.9 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 EJS44050.1 - 1.6e-20 74.1 5.1 5.6e-07 29.7 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJS44050.1 - 4.5e-10 39.3 0.8 0.07 12.6 0.1 4.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EJS44050.1 - 1.1e-07 32.0 0.1 0.00061 19.7 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 EJS44050.1 - 2.2e-07 30.5 0.0 0.009 15.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EJS44050.1 - 2.3e-07 31.5 5.9 0.079 13.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 EJS44050.1 - 1.7e-06 28.6 0.1 0.025 15.2 0.0 3.5 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 EJS44050.1 - 2.3e-06 27.7 0.0 0.0065 16.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EJS44050.1 - 4.4e-06 27.0 0.0 0.059 13.6 0.0 3.0 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 EJS44050.1 - 1.9e-05 25.0 0.0 0.22 11.9 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.6 EJS44050.1 - 1.9e-05 25.1 0.0 0.053 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EJS44050.1 - 2e-05 24.6 0.7 0.3 11.0 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA PF00004.29 EJS44050.1 - 3.5e-05 24.2 0.1 0.25 11.8 0.0 3.4 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EJS44050.1 - 4.2e-05 23.9 0.0 0.17 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EJS44050.1 - 7.9e-05 22.8 0.0 0.16 12.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EJS44050.1 - 0.00012 22.0 10.4 0.059 13.1 0.0 4.1 3 2 0 5 5 5 2 AAA ATPase domain MCM PF00493.23 EJS44050.1 - 0.00012 21.3 0.0 0.23 10.5 0.0 2.6 2 0 0 2 2 2 2 MCM P-loop domain AAA_24 PF13479.6 EJS44050.1 - 0.00013 21.8 0.4 0.25 11.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 EJS44050.1 - 0.00016 21.6 0.0 0.37 10.7 0.0 2.6 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_14 PF13173.6 EJS44050.1 - 0.00053 20.0 0.0 1.3 9.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 EJS44050.1 - 0.0028 17.9 0.0 1.3 9.2 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EJS44050.1 - 0.0036 16.5 0.0 0.5 9.5 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain AAA_5 PF07728.14 EJS44050.1 - 0.0045 17.0 0.0 3.7 7.5 0.1 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EJS44050.1 - 0.0047 16.0 0.0 0.063 12.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 EJS44050.1 - 0.007 16.0 0.1 0.78 9.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain VirE PF05272.11 EJS44050.1 - 0.0074 16.0 0.0 1.4 8.7 0.0 3.0 3 0 0 3 3 3 1 Virulence-associated protein E DUF815 PF05673.13 EJS44050.1 - 0.011 15.0 0.1 4.7 6.3 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 EJS44050.1 - 0.012 15.7 0.2 2.4 8.2 0.0 2.9 2 1 1 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 EJS44050.1 - 0.012 14.6 0.0 1.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 EJS44050.1 - 0.014 14.6 0.2 2.6 7.1 0.0 3.1 3 1 1 4 4 4 0 G-protein alpha subunit AAA_7 PF12775.7 EJS44050.1 - 0.015 14.8 0.1 1.2 8.6 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EJS44050.1 - 0.015 15.0 0.0 0.38 10.5 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.17 EJS44050.1 - 0.015 15.4 0.4 15 5.6 0.0 3.4 3 1 0 3 3 3 0 Helicase HerA, central domain CLP1_P PF16575.5 EJS44050.1 - 0.018 14.8 0.5 20 4.9 0.0 3.4 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Dynamin_N PF00350.23 EJS44050.1 - 0.021 14.9 6.6 3.8 7.5 0.0 4.2 3 1 0 4 4 3 0 Dynamin family DUF2813 PF11398.8 EJS44050.1 - 0.051 12.8 0.1 5.1 6.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) PduV-EutP PF10662.9 EJS44050.1 - 0.058 13.1 0.1 19 5.0 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 EJS44050.1 - 0.058 13.1 0.2 2.6 7.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EJS44050.1 - 0.067 13.1 0.1 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.18 EJS44050.1 - 0.068 12.7 0.0 3.1 7.3 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B dNK PF01712.19 EJS44050.1 - 0.072 12.9 0.1 10 5.9 0.0 2.7 3 0 0 3 3 2 0 Deoxynucleoside kinase AAA_27 PF13514.6 EJS44050.1 - 6.2 6.4 10.7 5.9 6.4 0.0 3.5 4 0 0 4 4 3 0 AAA domain HAD_2 PF13419.6 EJS44051.1 - 3e-08 34.0 0.1 5.6e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EJS44051.1 - 2.7e-06 27.8 0.0 1e-05 26.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Nse5 PF08691.10 EJS44052.1 - 1.3e-59 202.3 24.1 1.7e-59 201.9 24.1 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 DUF226 PF02890.14 EJS44052.1 - 0.023 14.7 1.4 0.023 14.7 1.4 2.4 1 1 1 2 2 2 0 Borrelia family of unknown function DUF226 UAA PF08449.11 EJS44053.1 - 7.4e-07 28.7 13.2 9.6e-07 28.3 13.2 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EJS44053.1 - 1.7e-06 28.2 23.0 3.6e-06 27.2 10.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family TRAP-gamma PF07074.12 EJS44053.1 - 0.3 10.7 4.8 0.092 12.3 0.8 2.1 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) PHO4 PF01384.20 EJS44053.1 - 4 6.4 12.0 0.27 10.2 4.0 2.2 1 1 1 2 2 2 0 Phosphate transporter family DUF4131 PF13567.6 EJS44053.1 - 5.4 6.6 7.7 4.2 7.0 0.3 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) GATA PF00320.27 EJS44054.1 - 5.1e-16 58.0 4.0 1.2e-15 56.8 4.0 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EJS44054.1 - 0.14 11.7 0.6 0.3 10.6 0.6 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding PMSR PF01625.21 EJS44055.1 - 2.2e-50 170.8 0.1 2.7e-50 170.5 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase AdoHcyase PF05221.17 EJS44056.1 - 5.5e-131 436.2 0.0 1.6e-74 250.8 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EJS44056.1 - 5.5e-85 283.4 2.7 9.1e-85 282.7 2.7 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EJS44056.1 - 3.4e-07 29.8 0.1 6.4e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EJS44056.1 - 0.00068 19.9 0.2 0.0013 18.9 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.12 EJS44056.1 - 0.00088 18.9 0.3 0.0016 18.1 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain PALP PF00291.25 EJS44056.1 - 0.12 11.7 1.4 0.32 10.3 0.6 1.9 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme DUF2572 PF10833.8 EJS44056.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Erg28 PF03694.13 EJS44057.1 - 8e-44 148.5 1.9 1e-43 148.2 1.9 1.1 1 0 0 1 1 1 1 Erg28 like protein MtN3_slv PF03083.16 EJS44057.1 - 0.0055 16.7 1.4 0.01 15.8 0.7 1.9 1 1 1 2 2 2 1 Sugar efflux transporter for intercellular exchange AAA PF00004.29 EJS44059.1 - 9.9e-40 136.0 0.0 2.3e-39 134.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS44059.1 - 7.5e-08 32.1 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EJS44059.1 - 2.7e-07 30.5 0.0 1.6e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 EJS44059.1 - 1.5e-05 25.3 0.2 0.00076 19.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EJS44059.1 - 4.1e-05 23.4 0.1 0.00011 22.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EJS44059.1 - 0.00014 22.1 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EJS44059.1 - 0.00024 21.1 0.1 0.012 15.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EJS44059.1 - 0.00064 20.1 0.1 0.0092 16.4 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 EJS44059.1 - 0.00089 18.6 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EJS44059.1 - 0.0011 19.0 0.1 0.0075 16.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EJS44059.1 - 0.0051 16.2 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EJS44059.1 - 0.0056 16.3 0.1 0.37 10.4 0.0 2.4 1 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EJS44059.1 - 0.0056 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 EJS44059.1 - 0.012 14.8 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EJS44059.1 - 0.02 15.0 0.0 0.077 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EJS44059.1 - 0.035 14.3 0.5 0.6 10.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 EJS44059.1 - 0.054 14.0 0.1 0.24 11.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain Chromo PF00385.24 EJS44059.1 - 0.074 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.12 EJS44059.1 - 0.15 12.0 0.0 0.45 10.4 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Complex1_LYR PF05347.15 EJS44060.1 - 2.9e-16 59.2 0.6 3.5e-16 59.0 0.6 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EJS44060.1 - 0.00079 20.1 0.5 0.00089 20.0 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like MIF4G PF02854.19 EJS44060.1 - 0.0045 16.6 0.2 0.0051 16.5 0.2 1.2 1 0 0 1 1 1 1 MIF4G domain Complex1_LYR_1 PF13232.6 EJS44060.1 - 0.0063 17.1 0.1 0.0078 16.8 0.1 1.2 1 1 0 1 1 1 1 Complex1_LYR-like Cupin_8 PF13621.6 EJS44061.1 - 2.9e-06 27.2 4.7 0.00012 21.9 3.8 2.9 1 1 0 2 2 2 1 Cupin-like domain PHD PF00628.29 EJS44061.1 - 0.0013 18.6 8.0 0.0019 18.1 6.8 2.0 1 1 0 1 1 1 1 PHD-finger JmjC PF02373.22 EJS44061.1 - 0.0065 16.9 0.0 0.19 12.2 0.0 2.9 2 1 0 2 2 2 1 JmjC domain, hydroxylase C1_1 PF00130.22 EJS44061.1 - 0.038 13.9 5.4 0.085 12.8 5.4 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) JHD PF17811.1 EJS44061.1 - 0.039 14.5 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Jumonji helical domain Cupin_4 PF08007.12 EJS44061.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_1 PF00190.22 EJS44061.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 EJS44061.1 - 0.16 11.7 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain TAXi_N PF14543.6 EJS44061.1 - 0.17 12.1 0.8 0.3 11.3 0.8 1.3 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Mito_carr PF00153.27 EJS44062.1 - 1.9e-43 146.3 6.0 1.5e-16 60.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ArsP_2 PF11449.8 EJS44062.1 - 0.034 13.4 0.1 0.05 12.8 0.1 1.2 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter Gti1_Pac2 PF09729.9 EJS44064.1 - 7.4e-57 192.4 0.0 7.4e-57 192.4 0.0 4.5 4 1 0 4 4 4 2 Gti1/Pac2 family UAA PF08449.11 EJS44066.1 - 4.2e-100 334.9 13.8 4.7e-100 334.7 13.8 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 EJS44066.1 - 4.3e-06 26.3 2.3 4.3e-06 26.3 2.3 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 EJS44066.1 - 6.6 6.9 22.3 6.9 6.8 8.8 3.1 2 2 0 2 2 2 0 EamA-like transporter family DUF997 PF06196.12 EJS44066.1 - 8.4 6.5 8.3 1.3 9.1 2.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF997) TPP_enzyme_N PF02776.18 EJS44067.1 - 3.9e-43 147.0 0.0 7.9e-41 139.5 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EJS44067.1 - 3.7e-27 94.7 0.0 9.7e-27 93.4 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EJS44067.1 - 1e-19 70.8 0.1 6.6e-19 68.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain zf-Nse PF11789.8 EJS44068.1 - 9e-23 79.9 1.5 1.5e-22 79.2 0.6 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EJS44068.1 - 0.00059 19.8 1.8 0.00059 19.8 1.8 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EJS44068.1 - 0.0016 18.3 1.2 0.0042 16.9 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EJS44068.1 - 0.0081 16.2 0.5 0.018 15.0 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EJS44068.1 - 0.013 15.4 0.4 0.035 14.0 0.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 EJS44068.1 - 0.015 15.1 0.7 0.015 15.1 0.7 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_2 PF13639.6 EJS44068.1 - 0.02 15.2 1.2 0.062 13.6 1.2 1.9 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 EJS44068.1 - 0.025 14.9 0.3 0.077 13.3 0.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Fzo_mitofusin PF04799.13 EJS44068.1 - 0.21 11.2 1.4 1 8.9 0.1 2.0 2 0 0 2 2 2 0 fzo-like conserved region PCI PF01399.27 EJS44069.1 - 0.1 13.1 0.8 0.27 11.8 0.1 2.2 2 1 1 3 3 3 0 PCI domain PMP1_2 PF08114.11 EJS44070.1 - 1.4e-32 111.2 4.3 1.5e-32 111.1 4.3 1.0 1 0 0 1 1 1 1 ATPase proteolipid family Cytochrom_B558a PF05038.13 EJS44070.1 - 0.091 12.3 0.2 0.091 12.3 0.2 1.0 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit CD34_antigen PF06365.12 EJS44070.1 - 0.16 11.6 0.5 0.17 11.5 0.5 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family YjeF_N PF03853.15 EJS44072.1 - 8e-37 126.8 0.0 1.6e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EJS44072.1 - 3.4e-20 72.8 13.6 3.4e-20 72.8 13.6 2.5 2 0 0 2 2 2 1 FDF domain RITA PF17066.5 EJS44072.1 - 0.0041 16.7 1.6 0.008 15.8 1.6 1.5 1 0 0 1 1 1 1 RBPJ-interacting and tubulin associated protein Ripply PF14998.6 EJS44072.1 - 0.43 11.2 5.7 0.49 11.1 0.0 3.1 3 0 0 3 3 3 0 Transcription Regulator Arm PF00514.23 EJS44073.1 - 2.7e-73 240.0 26.3 1.9e-12 46.7 0.0 10.6 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EJS44073.1 - 5.6e-20 71.4 16.4 0.00024 21.6 0.1 8.4 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 EJS44073.1 - 7.3e-18 64.7 9.1 0.00035 20.9 0.0 7.2 3 2 5 8 8 8 5 HEAT repeats Adaptin_N PF01602.20 EJS44073.1 - 1.8e-12 46.6 25.6 6.1e-08 31.7 3.3 3.4 1 1 2 3 3 3 3 Adaptin N terminal region HEAT PF02985.22 EJS44073.1 - 4.1e-11 42.1 29.0 0.063 13.6 0.2 10.3 12 0 0 12 12 11 3 HEAT repeat KAP PF05804.12 EJS44073.1 - 1.7e-10 39.8 0.6 6.1e-10 37.9 0.6 1.8 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.13 EJS44073.1 - 1.9e-08 34.1 11.5 5.1e-07 29.4 2.5 3.1 3 1 0 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 EJS44073.1 - 2.4e-06 27.7 2.4 0.097 12.8 0.1 4.7 3 2 1 5 5 5 2 V-ATPase subunit H DUF3361 PF11841.8 EJS44073.1 - 2.5e-06 27.5 6.3 0.0027 17.7 0.2 4.4 1 1 3 5 5 5 1 Domain of unknown function (DUF3361) Cnd1 PF12717.7 EJS44073.1 - 7.6e-06 26.1 11.5 0.17 11.9 0.3 5.1 1 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EJS44073.1 - 3e-05 24.6 0.3 0.36 11.4 0.0 4.0 3 2 1 4 4 3 2 Vacuolar 14 Fab1-binding region V-ATPase_H_N PF03224.14 EJS44073.1 - 4.6e-05 22.9 5.1 0.0034 16.7 1.8 3.5 1 1 1 2 2 2 1 V-ATPase subunit H Tti2 PF10521.9 EJS44073.1 - 0.00034 20.3 0.0 0.036 13.6 0.0 3.1 3 0 0 3 3 3 1 Tti2 family Proteasom_PSMB PF10508.9 EJS44073.1 - 0.0025 16.4 2.0 4 5.8 0.0 3.3 1 1 2 3 3 3 2 Proteasome non-ATPase 26S subunit RIF5_SNase_1 PF18187.1 EJS44073.1 - 0.02 14.7 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 TbRIF5 SNase domain 1 RasGEF_N_2 PF14663.6 EJS44073.1 - 0.036 14.5 3.5 57 4.2 0.1 4.9 3 2 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF5578 PF17741.1 EJS44073.1 - 0.094 12.1 8.6 2.6 7.4 0.3 3.9 2 2 2 5 5 5 0 Family of unknown function (DUF5578) Alpha-amylase_C PF02806.18 EJS44074.1 - 2.2e-27 95.4 0.4 6.6e-27 93.8 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EJS44074.1 - 1.2e-16 60.8 0.0 3.5e-16 59.3 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EJS44074.1 - 1.2e-13 51.3 0.2 8.9e-13 48.5 0.1 2.3 1 1 1 2 2 2 1 Alpha amylase, catalytic domain Glyco_hydro_66 PF13199.6 EJS44074.1 - 0.031 12.9 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Tenui_N PF05733.11 EJS44074.1 - 0.088 12.3 0.0 15 5.0 0.0 2.1 2 0 0 2 2 2 0 Tenuivirus/Phlebovirus nucleocapsid protein AMPK1_CBM PF16561.5 EJS44074.1 - 0.098 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Acetyltransf_1 PF00583.25 EJS44075.1 - 1.5e-10 41.3 0.1 1.8e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EJS44075.1 - 0.00025 21.4 0.3 0.00042 20.7 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJS44075.1 - 0.00035 20.5 0.0 0.00064 19.6 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EJS44075.1 - 0.0018 18.2 0.1 0.0027 17.6 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EJS44075.1 - 0.0019 18.9 0.1 0.0023 18.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EJS44075.1 - 0.0097 16.0 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 EJS44075.1 - 0.037 13.8 0.0 0.075 12.8 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ MFS_1 PF07690.16 EJS44076.1 - 1.9e-11 43.5 79.7 9.6e-09 34.6 47.4 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EJS44076.1 - 6.4e-05 22.0 9.5 6.4e-05 22.0 9.5 3.0 4 0 0 4 4 4 2 Sugar (and other) transporter Aa_trans PF01490.18 EJS44077.1 - 9.2e-97 324.3 31.6 1e-96 324.1 31.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5392 PF17370.2 EJS44077.1 - 0.085 12.9 0.1 0.26 11.4 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5392) NPR2 PF06218.11 EJS44078.1 - 6.6e-127 423.9 3.0 1.3e-126 423.0 3.0 1.3 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Kinesin PF00225.23 EJS44079.1 - 8.8e-95 317.4 11.2 2e-62 211.1 6.9 4.0 4 1 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 EJS44079.1 - 4.6e-21 75.3 0.0 4.6e-21 75.3 0.0 3.5 4 2 0 4 4 4 1 Microtubule binding Enterotoxin_b PF01376.18 EJS44079.1 - 0.0093 16.1 0.3 0.07 13.3 0.3 2.6 1 0 0 1 1 1 1 Heat-labile enterotoxin beta chain DUF2730 PF10805.8 EJS44079.1 - 3.5 7.8 12.7 0.39 10.8 0.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) HalX PF08663.10 EJS44079.1 - 7.1 7.0 10.9 2.2 8.6 1.8 3.9 2 1 2 4 4 4 0 HalX domain Peptidase_S8 PF00082.22 EJS44080.1 - 4.6e-33 114.7 5.4 4.6e-33 114.7 5.4 2.0 2 1 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 EJS44080.1 - 6.3e-12 46.0 0.3 6.3e-12 46.0 0.3 2.5 3 0 0 3 3 3 1 Peptidase inhibitor I9 Mitochondr_Som1 PF11093.8 EJS44081.1 - 6.4e-12 45.3 0.6 1e-11 44.6 0.6 1.4 1 1 0 1 1 1 1 Mitochondrial export protein Som1 PGM_PMM_I PF02878.16 EJS44082.1 - 1.2e-15 57.5 0.0 4e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EJS44082.1 - 2.9e-10 40.2 0.0 8.8e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 EJS44082.1 - 0.13 12.9 0.1 0.55 10.9 0.1 2.1 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DltD PF04914.12 EJS44083.1 - 0.02 14.3 1.0 0.031 13.7 1.0 1.4 1 1 0 1 1 1 0 DltD protein CAF1C_H4-bd PF12265.8 EJS44084.1 - 3.8e-25 87.9 0.4 3.9e-24 84.7 0.1 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EJS44084.1 - 3.3e-14 53.0 1.3 0.00033 21.4 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Ribosomal_L11_N PF03946.14 EJS44085.1 - 2.6e-21 75.2 0.3 4.6e-21 74.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EJS44085.1 - 6.2e-17 61.9 1.2 1.1e-16 61.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain AFG1_ATPase PF03969.16 EJS44086.1 - 5.9e-72 242.5 0.0 1.7e-65 221.3 0.0 3.5 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EJS44086.1 - 4.5e-06 27.2 0.1 8.7e-05 23.0 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EJS44086.1 - 0.0037 17.7 0.0 0.0078 16.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EJS44086.1 - 0.0052 16.7 0.0 0.0083 16.1 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 EJS44086.1 - 0.0054 16.6 0.1 0.011 15.5 0.1 1.6 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_22 PF13401.6 EJS44086.1 - 0.0088 16.3 0.1 0.024 14.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EJS44086.1 - 0.021 15.2 0.0 0.074 13.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 EJS44086.1 - 0.027 14.4 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EJS44086.1 - 0.043 13.7 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EJS44086.1 - 0.076 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EJS44086.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATP-synt_D PF01813.17 EJS44087.1 - 6.4e-69 231.7 4.0 8.2e-69 231.4 4.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 EJS44087.1 - 0.023 14.2 0.4 0.035 13.6 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) RICH PF05062.12 EJS44087.1 - 0.28 11.6 5.8 0.27 11.6 2.2 2.3 2 0 0 2 2 2 0 RICH domain Ribosomal_L2_C PF03947.18 EJS44088.1 - 3.8e-53 179.0 2.3 3.8e-53 179.0 2.3 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EJS44088.1 - 2.6e-26 91.4 0.1 6.2e-26 90.2 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SRP1_TIP1 PF00660.17 EJS44089.1 - 2.2e-27 95.0 0.0 2.9e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family Sedlin_N PF04628.13 EJS44090.1 - 3.7e-12 46.5 0.1 4.2e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FAD_binding_2 PF00890.24 EJS44091.1 - 3e-72 244.0 0.0 3.4e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJS44091.1 - 1.2e-12 48.1 0.0 7.2e-08 32.4 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EJS44091.1 - 3e-08 33.3 0.0 6.8e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EJS44091.1 - 3.8e-08 33.5 0.0 1.2e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EJS44091.1 - 2.9e-07 29.9 0.0 0.011 14.8 0.1 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EJS44091.1 - 3.9e-07 29.6 1.2 2e-06 27.2 0.9 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJS44091.1 - 3e-06 26.2 1.0 0.018 13.8 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 EJS44091.1 - 1.2e-05 24.7 0.1 0.029 13.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EJS44091.1 - 2.9e-05 23.4 2.0 0.00064 19.0 0.5 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EJS44091.1 - 0.00012 22.5 0.3 0.35 11.5 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJS44091.1 - 0.00048 20.1 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 EJS44091.1 - 0.0013 17.6 0.1 0.22 10.3 0.0 2.1 2 0 0 2 2 2 2 MCRA family Amino_oxidase PF01593.24 EJS44091.1 - 0.004 16.5 0.0 0.65 9.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DUF903 PF06004.12 EJS44091.1 - 0.037 13.9 0.1 0.037 13.9 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) GMC_oxred_N PF00732.19 EJS44091.1 - 0.064 12.6 0.9 4.6 6.5 0.0 2.5 3 0 0 3 3 3 0 GMC oxidoreductase Trp_halogenase PF04820.14 EJS44091.1 - 0.08 11.8 0.0 3.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 EJS44091.1 - 0.11 11.8 0.2 0.34 10.2 0.2 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Beta_elim_lyase PF01212.21 EJS44092.1 - 5.4e-79 265.5 0.0 6.5e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Peptidase_M78 PF06114.13 EJS44092.1 - 0.03 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 IrrE N-terminal-like domain DnaI_N PF07319.11 EJS44093.1 - 0.011 16.4 8.4 0.31 11.7 0.3 3.6 2 1 1 3 3 3 0 Primosomal protein DnaI N-terminus fn3 PF00041.21 EJS44093.1 - 0.032 14.6 0.1 0.32 11.4 0.1 2.6 1 1 0 1 1 1 0 Fibronectin type III domain DUF4041 PF13250.6 EJS44093.1 - 0.54 10.2 3.8 0.42 10.5 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) NAD_kinase PF01513.21 EJS44094.1 - 1.5e-90 303.4 0.0 2e-90 303.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Ivy PF08816.11 EJS44094.1 - 0.076 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Inhibitor of vertebrate lysozyme (Ivy) DAGK_cat PF00781.24 EJS44094.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Glyco_hydro_16 PF00722.21 EJS44095.1 - 4e-41 140.4 4.7 4e-41 140.4 4.7 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 YcgR_2 PF12945.7 EJS44095.1 - 0.0086 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Flagellar protein YcgR Chitin_bind_1 PF00187.19 EJS44095.1 - 0.05 14.1 13.2 0.11 13.0 13.2 1.6 1 0 0 1 1 1 0 Chitin recognition protein SOG2 PF10428.9 EJS44095.1 - 3.6 6.7 22.6 5.2 6.2 22.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cytochrom_C PF00034.21 EJS44096.1 - 2.3e-10 41.5 0.6 4.5e-10 40.5 0.6 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EJS44096.1 - 1.4e-07 31.8 2.0 1.6e-06 28.4 2.0 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EJS44096.1 - 0.006 16.3 0.9 0.015 15.0 0.2 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.14 EJS44096.1 - 0.044 14.4 0.0 0.047 14.3 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrome_P460 PF16694.5 EJS44096.1 - 0.11 12.8 1.0 5.4 7.4 0.1 2.1 2 0 0 2 2 2 0 Cytochrome P460 UBA PF00627.31 EJS44097.1 - 1.7e-30 104.5 3.7 3.6e-16 58.7 0.3 2.4 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EJS44097.1 - 1.8e-18 66.0 0.3 3.6e-18 65.1 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 EJS44097.1 - 2.1e-11 43.4 0.3 4.1e-11 42.4 0.3 1.4 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 EJS44097.1 - 2.5e-06 27.2 0.1 8.5e-06 25.5 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EJS44097.1 - 4.9e-06 26.6 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EJS44097.1 - 2.6e-05 24.5 0.1 4.5e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 EJS44097.1 - 0.0013 19.2 0.1 0.0032 18.0 0.1 1.7 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain CUE PF02845.16 EJS44097.1 - 0.0044 16.7 1.3 2.6 7.9 0.0 4.3 3 2 1 4 4 4 1 CUE domain DUF1421 PF07223.11 EJS44097.1 - 0.028 14.2 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain (DUF1421) RepB PF07506.11 EJS44097.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 RepB plasmid partitioning protein UBA_2 PF08587.11 EJS44097.1 - 0.11 12.6 0.1 0.73 10.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Anp1 PF03452.14 EJS44098.1 - 1.2e-113 378.9 1.1 1.8e-112 375.1 0.0 2.2 2 0 0 2 2 2 1 Anp1 Suf PF05843.14 EJS44098.1 - 0.024 14.6 5.7 0.044 13.8 5.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 EJS44098.1 - 0.078 12.6 29.2 0.2 11.2 28.4 2.0 2 0 0 2 2 2 0 Spt20 family Neur_chan_memb PF02932.16 EJS44098.1 - 0.11 12.5 0.7 0.17 11.9 0.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 EJS44098.1 - 0.17 10.8 11.1 0.64 8.9 11.2 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ALMT PF11744.8 EJS44098.1 - 0.52 9.1 1.9 0.69 8.7 1.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Pex14_N PF04695.13 EJS44098.1 - 0.67 10.6 11.4 1.2 9.8 11.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C PF13299.6 EJS44098.1 - 0.86 9.8 8.4 1.4 9.0 8.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GvpL_GvpF PF06386.11 EJS44098.1 - 0.91 9.4 7.0 2 8.3 6.7 1.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF MAJIN PF15077.6 EJS44098.1 - 1.2 8.9 8.5 2.1 8.1 8.5 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF2722 PF10846.8 EJS44098.1 - 1.3 7.9 25.6 2.3 7.1 25.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CobT PF06213.12 EJS44098.1 - 5.1 6.4 15.3 8.7 5.6 15.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Roughex PF06020.11 EJS44098.1 - 5.4 6.0 15.0 7.9 5.5 15.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein AIF_C PF14721.6 EJS44098.1 - 6.9 7.0 7.9 11 6.3 6.7 1.9 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term eIF-5a PF01287.20 EJS44099.1 - 4.8e-30 103.5 0.5 6.8e-30 103.0 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EJS44099.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain TgMIC1 PF11476.8 EJS44099.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 MCM PF00493.23 EJS44100.1 - 9e-98 325.8 0.4 1.4e-97 325.2 0.4 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EJS44100.1 - 7.4e-33 113.1 0.0 1.5e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EJS44100.1 - 8.1e-25 87.1 1.3 2.1e-24 85.7 1.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EJS44100.1 - 1.3e-07 32.1 0.6 2.1e-06 28.3 0.1 3.0 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EJS44100.1 - 1.5e-07 31.0 0.0 1.8e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EJS44100.1 - 0.0031 17.4 0.4 0.0088 15.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EJS44100.1 - 0.018 14.7 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ORC6 PF05460.13 EJS44100.1 - 0.1 11.8 7.2 0.19 11.0 7.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AAA_5 PF07728.14 EJS44100.1 - 0.13 12.2 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) E1-E2_ATPase PF00122.20 EJS44101.1 - 1.1e-17 64.2 0.2 2.6e-17 62.9 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EJS44101.1 - 3.9e-16 60.0 0.0 2.5e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJS44101.1 - 9.3e-06 25.6 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EJS44101.1 - 0.0041 16.9 0.2 0.023 14.4 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EJS44101.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Perilipin PF03036.16 EJS44101.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Perilipin family Phos_pyr_kin PF08543.12 EJS44102.1 - 3.6e-11 42.9 0.0 4.7e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EJS44102.1 - 6.1e-07 29.0 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ATP-synt_C PF00137.21 EJS44103.1 - 4.6e-34 116.6 30.8 6.4e-22 77.7 12.8 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 EJS44103.1 - 1.8 8.5 9.4 0.87 9.5 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Ribosomal_L7Ae PF01248.26 EJS44104.1 - 1e-27 95.7 0.1 1.2e-27 95.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EJS44104.1 - 0.0019 18.0 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 EJS44104.1 - 0.017 15.2 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 Rieske PF00355.26 EJS44105.1 - 5.5e-11 42.3 0.0 8.9e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EJS44105.1 - 4.2e-09 36.7 0.5 9.1e-09 35.7 0.5 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region DUF2235 PF09994.9 EJS44106.1 - 9.6e-82 274.6 0.0 1.5e-81 273.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) OMPdecase PF00215.24 EJS44107.1 - 9.7e-76 254.3 0.0 1.1e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family zf-Tim10_DDP PF02953.15 EJS44108.1 - 3.6e-20 71.4 7.8 5.4e-20 70.8 7.8 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 EJS44108.1 - 0.031 14.6 0.1 0.36 11.1 0.0 2.0 1 1 1 2 2 2 0 Phasin protein Tam41_Mmp37 PF09139.11 EJS44108.1 - 0.049 13.1 0.5 0.056 12.9 0.5 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Iron_permease PF04120.12 EJS44109.1 - 2.6e-27 95.1 23.3 2.2e-14 53.3 1.3 5.2 5 0 0 5 5 5 5 Low affinity iron permease Shisa PF13908.6 EJS44109.1 - 0.061 13.6 1.6 0.66 10.2 0.0 2.9 4 0 0 4 4 4 0 Wnt and FGF inhibitory regulator Exo_endo_phos PF03372.23 EJS44110.1 - 2e-34 119.1 0.0 2.5e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNB PF00773.19 EJS44111.1 - 6.7e-70 236.0 0.1 1.7e-69 234.7 0.0 1.7 2 0 0 2 2 2 1 RNB domain HECW1_helix PF18436.1 EJS44111.1 - 0.15 12.1 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 DEAD PF00270.29 EJS44112.1 - 3.7e-46 157.1 0.5 9.1e-46 155.8 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS44112.1 - 6.8e-26 90.8 0.1 5.5e-25 87.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EJS44112.1 - 2.5e-19 69.3 0.5 4.7e-19 68.4 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EJS44112.1 - 6.7e-06 26.2 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EJS44112.1 - 4.8e-05 22.7 0.0 0.00014 21.2 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 EJS44112.1 - 0.006 15.9 0.0 0.016 14.5 0.0 1.7 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_30 PF13604.6 EJS44112.1 - 0.16 11.7 0.0 1 9.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EJS44112.1 - 0.25 11.6 2.6 0.65 10.3 1.4 2.4 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 EJS44113.1 - 2.3e-48 164.8 1.8 4.4e-47 160.7 0.8 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44113.1 - 1.8e-23 83.2 0.8 5.3e-21 75.1 0.3 3.1 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJS44113.1 - 0.0015 17.4 0.1 0.0043 15.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EJS44113.1 - 0.0035 16.7 0.5 0.83 8.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Amidase PF01425.21 EJS44114.1 - 5.1e-132 441.0 0.0 5.7e-132 440.9 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF2406 PF10295.9 EJS44115.1 - 9.2e-28 96.7 0.9 1.7e-27 95.9 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) DUF3484 PF11983.8 EJS44115.1 - 0.026 15.6 3.7 0.031 15.4 1.6 2.2 2 1 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Rotamase_3 PF13616.6 EJS44115.1 - 0.081 13.5 1.9 0.098 13.2 0.3 1.8 2 0 0 2 2 2 0 PPIC-type PPIASE domain Aminotran_1_2 PF00155.21 EJS44116.1 - 4.1e-85 286.1 0.1 4.9e-85 285.9 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_S10 PF00450.22 EJS44117.1 - 9.6e-127 423.8 0.3 1.2e-126 423.6 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EJS44117.1 - 2e-21 76.9 4.1 2e-19 70.3 4.1 2.6 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide GATase_6 PF13522.6 EJS44119.1 - 5e-13 49.4 0.0 1.4e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EJS44119.1 - 1.3e-09 38.1 0.0 2.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EJS44119.1 - 2.7e-09 36.7 0.0 5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EJS44119.1 - 2.8e-05 23.2 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II RNA12 PF10443.9 EJS44120.1 - 2.3e-180 600.1 4.7 2.7e-179 596.6 2.5 2.1 2 0 0 2 2 2 2 RNA12 protein RRM_1 PF00076.22 EJS44120.1 - 2.2e-08 33.8 0.0 4.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 EJS44120.1 - 1.7e-05 24.8 0.5 0.00025 21.0 0.1 2.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EJS44120.1 - 0.0061 16.6 0.5 0.038 14.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain CP12 PF02672.15 EJS44120.1 - 0.032 15.0 0.1 0.35 11.6 0.0 2.5 2 0 0 2 2 2 0 CP12 domain Cytochrom_B559a PF00284.20 EJS44120.1 - 0.08 12.7 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit ADH_N PF08240.12 EJS44121.1 - 1.2e-29 102.3 1.9 1.3e-29 102.3 0.2 1.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJS44121.1 - 2.3e-24 85.8 2.2 3.6e-24 85.2 2.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJS44121.1 - 3.6e-06 28.1 0.0 6.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase USP7_C2 PF14533.6 EJS44122.1 - 2.6e-57 193.9 2.9 2.6e-57 193.9 2.9 2.7 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EJS44122.1 - 3.7e-44 151.2 3.1 7e-44 150.2 3.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 EJS44122.1 - 1.2e-33 116.4 7.6 6.7e-33 114.0 0.1 3.2 2 2 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 EJS44122.1 - 2.6e-22 79.8 2.5 6.9e-22 78.5 0.4 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UN_NPL4 PF11543.8 EJS44122.1 - 0.65 10.5 3.4 1.2 9.6 0.3 3.2 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Glucan_synthase PF02364.15 EJS44123.1 - 0 1378.3 0.7 0 1378.3 0.7 2.1 1 1 1 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EJS44123.1 - 9.8e-44 148.8 1.2 4.3e-43 146.7 1.2 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Osmo_CC PF08946.10 EJS44123.1 - 0.12 12.7 0.7 0.6 10.4 0.1 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Glyco_hydro_72 PF03198.14 EJS44124.1 - 8.2e-149 495.1 13.8 1.4e-148 494.3 13.8 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EJS44124.1 - 1.3e-29 102.6 4.9 5.5e-29 100.7 4.9 2.2 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EJS44124.1 - 0.00094 18.7 0.9 0.0066 15.9 0.9 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Corona_nucleoca PF00937.18 EJS44124.1 - 2.2 7.2 12.6 3.8 6.4 12.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Importin_rep_6 PF18829.1 EJS44125.1 - 8.4e-47 157.8 2.6 8.4e-47 157.8 2.6 3.7 3 0 0 3 3 3 1 Importin repeat 6 Importin_rep_4 PF18808.1 EJS44125.1 - 1e-33 115.4 1.1 1e-33 115.4 1.1 3.2 3 0 0 3 3 2 1 Importin repeat HEAT_EZ PF13513.6 EJS44125.1 - 2.8e-22 78.8 4.2 8.6e-11 42.1 0.0 8.3 6 1 2 8 8 7 3 HEAT-like repeat Importin_rep_5 PF18816.1 EJS44125.1 - 9.3e-21 73.9 2.6 3.2e-20 72.2 0.0 3.3 3 0 0 3 3 3 1 Importin repeat HEAT PF02985.22 EJS44125.1 - 7.1e-15 53.8 4.1 0.078 13.3 0.0 10.1 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 EJS44125.1 - 8.1e-14 51.8 0.2 2.6e-05 24.5 0.0 7.0 4 2 2 6 6 6 3 HEAT repeats RIX1 PF08167.12 EJS44125.1 - 1.2e-08 34.9 2.1 0.0027 17.5 0.2 5.6 5 1 1 6 6 6 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 EJS44125.1 - 9.6e-07 28.6 1.3 0.0016 18.0 0.4 3.6 4 0 0 4 4 4 2 CLASP N terminal MMS19_C PF12460.8 EJS44125.1 - 1.1e-06 28.1 6.6 0.00012 21.3 1.6 3.1 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 EJS44125.1 - 5.1e-06 27.0 0.8 1.2 9.8 0.0 6.8 4 2 2 8 8 8 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EJS44125.1 - 0.00025 21.0 6.5 0.21 11.5 0.3 6.3 5 3 0 5 5 5 1 Domain of unknown function (DUF3385) Arm PF00514.23 EJS44125.1 - 0.00037 20.4 2.9 5 7.3 0.1 5.5 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat IFRD PF05004.13 EJS44125.1 - 0.002 17.3 6.0 0.22 10.6 0.5 4.6 4 2 2 6 6 6 1 Interferon-related developmental regulator (IFRD) ParcG PF10274.9 EJS44125.1 - 0.0038 17.4 0.1 0.39 10.8 0.0 3.4 2 1 0 2 2 2 1 Parkin co-regulated protein DNA_alkylation PF08713.11 EJS44125.1 - 0.024 14.3 0.0 0.085 12.6 0.0 2.0 1 0 0 1 1 1 0 DNA alkylation repair enzyme eIF-3c_N PF05470.12 EJS44126.1 - 1.5e-196 654.3 28.0 1.1e-153 512.7 8.0 2.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EJS44126.1 - 6.5e-14 52.3 3.0 1.1e-13 51.6 0.2 2.8 2 1 0 2 2 2 1 PCI domain DUF5045 PF16464.5 EJS44126.1 - 3.1 8.2 6.4 41 4.6 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF5045) Methyltrn_RNA_3 PF02598.17 EJS44127.1 - 7.6e-62 209.4 0.0 9.3e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase RasGEF_N PF00618.20 EJS44128.1 - 9e-06 25.9 1.4 1.9e-05 24.8 1.4 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif ELP6 PF09807.9 EJS44128.1 - 3.1e-05 23.5 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Elongation complex protein 6 KRTAP7 PF15034.6 EJS44128.1 - 0.12 13.4 0.2 4.8 8.2 0.1 2.3 2 0 0 2 2 2 0 KRTAP type 7 family DUF3336 PF11815.8 EJS44129.1 - 2.7e-25 88.7 0.2 5.5e-25 87.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EJS44129.1 - 6.6e-08 33.0 0.0 1.3e-07 32.0 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Proteasome PF00227.26 EJS44130.1 - 1.8e-44 151.6 0.0 2.1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EJS44130.1 - 6.3e-12 44.9 0.1 1.3e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GFO_IDH_MocA PF01408.22 EJS44131.1 - 2.1e-26 93.1 0.2 4.5e-26 92.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EJS44131.1 - 3.3e-13 49.7 0.0 5.6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EJS44131.1 - 0.052 14.2 0.0 0.095 13.4 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Cyt-b5 PF00173.28 EJS44132.1 - 1.4e-20 73.2 0.2 4.8e-20 71.5 0.3 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EJS44132.1 - 6.1e-14 52.5 13.6 6.1e-14 52.5 13.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily CIDE-N PF02017.15 EJS44132.1 - 0.01 15.8 0.1 0.021 14.8 0.1 1.5 1 0 0 1 1 1 0 CIDE-N domain CPBP PF02517.16 EJS44133.1 - 3.4e-14 53.0 6.4 3.4e-14 53.0 6.4 2.2 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Bul1_N PF04425.12 EJS44134.1 - 2.2e-169 564.0 0.6 2.2e-169 564.0 0.6 1.6 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.12 EJS44134.1 - 1e-113 379.3 15.2 1e-113 379.3 15.2 2.3 3 0 0 3 3 3 1 Bul1 C terminus ubiquitin PF00240.23 EJS44135.1 - 3.7e-24 84.3 0.1 5.4e-24 83.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EJS44135.1 - 7e-12 45.0 0.0 1.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EJS44135.1 - 5.7e-06 26.7 0.0 1.2e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EJS44135.1 - 9.9e-06 25.6 0.1 2.7e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 EJS44135.1 - 6.9e-05 22.7 0.3 0.00018 21.4 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain TBK1_ULD PF18396.1 EJS44135.1 - 0.0048 16.8 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain HOIP-UBA PF16678.5 EJS44135.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair GerD PF17898.1 EJS44135.1 - 0.02 14.9 8.0 0.044 13.7 8.0 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain Ubiquitin_4 PF18036.1 EJS44135.1 - 0.029 14.4 0.1 8.5 6.5 0.0 2.2 1 1 1 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EJS44135.1 - 0.035 14.7 0.0 0.073 13.6 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UN_NPL4 PF11543.8 EJS44135.1 - 0.23 12.0 0.1 0.41 11.2 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 PGM_PMM_I PF02878.16 EJS44136.1 - 1.2e-38 132.0 0.0 2.4e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EJS44136.1 - 5.8e-19 68.6 0.0 1.5e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EJS44136.1 - 3.8e-12 46.4 0.0 6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EJS44136.1 - 5.6e-07 29.6 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PIG-L PF02585.17 EJS44137.1 - 4.6e-18 66.1 0.0 7.9e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.7 EJS44138.1 - 1.4e-28 99.0 0.2 1.5e-27 95.7 0.0 2.7 3 0 0 3 3 3 1 Mitochondrial ATPase expression Rit1_C PF17184.4 EJS44139.1 - 1.3e-97 326.5 0.2 7.8e-97 324.0 0.0 1.9 2 0 0 2 2 2 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EJS44139.1 - 6.5e-28 97.2 1.3 1.2e-27 96.4 0.2 2.0 2 0 0 2 2 2 1 Rit1 DUSP-like domain AAA_31 PF13614.6 EJS44139.1 - 0.027 14.4 0.3 0.067 13.1 0.3 1.6 1 0 0 1 1 1 0 AAA domain Pyridoxal_deC PF00282.19 EJS44140.1 - 1.1e-54 185.6 0.0 1.7e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cellulase-like PF12876.7 EJS44142.1 - 0.021 14.2 0.2 0.023 14.1 0.2 1.1 1 0 0 1 1 1 0 Sugar-binding cellulase-like SR-25 PF10500.9 EJS44142.1 - 0.025 14.2 1.7 0.031 13.9 1.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GFD1 PF17331.2 EJS44143.1 - 1.7e-07 31.2 13.6 4.4e-07 29.9 13.6 1.8 1 0 0 1 1 1 1 GFD1 mRNA transport factor PapD_C PF02753.17 EJS44143.1 - 0.026 14.9 0.2 1.4 9.3 0.3 2.5 2 0 0 2 2 2 0 Pili assembly chaperone PapD, C-terminal domain DUF5339 PF17274.2 EJS44143.1 - 4 8.3 15.5 1.8 9.5 0.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) MKRN1_C PF15815.5 EJS44143.1 - 4.3 7.8 7.3 0.22 11.9 1.0 2.0 2 1 1 3 3 3 0 E3 ubiquitin-protein ligase makorin-1, C-terminal DUF4551 PF15087.6 EJS44143.1 - 6.2 5.5 17.4 7.2 5.3 17.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) COX7a PF02238.15 EJS44144.1 - 7e-23 80.8 0.4 7.8e-23 80.6 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII F-box-like PF12937.7 EJS44145.1 - 0.00016 21.5 0.0 0.00043 20.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EJS44145.1 - 0.099 12.5 0.3 0.39 10.7 0.1 2.1 2 0 0 2 2 2 0 F-box domain eIF-1a PF01176.19 EJS44146.1 - 5e-20 71.1 0.0 6.9e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Glyco_transf_20 PF00982.21 EJS44147.1 - 2.7e-178 593.5 2.9 2.7e-178 593.5 2.9 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EJS44147.1 - 3.9e-50 170.2 0.0 6.3e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase VSP PF03302.13 EJS44147.1 - 0.098 11.5 0.1 0.2 10.5 0.1 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein TatD_DNase PF01026.21 EJS44148.1 - 1.7e-44 152.1 0.0 2e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EJS44148.1 - 0.044 13.6 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase Antimicrobial_6 PF08036.11 EJS44148.1 - 0.16 12.1 0.4 0.34 11.0 0.4 1.5 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide SAP30_Sin3_bdg PF13867.6 EJS44149.1 - 8.9e-12 45.2 0.7 7e-08 32.7 0.2 2.4 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Menin PF05053.13 EJS44149.1 - 0.019 13.4 5.9 0.02 13.3 5.9 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 EJS44149.1 - 0.026 13.1 6.2 0.026 13.1 6.2 1.1 1 0 0 1 1 1 0 Macoilin family Secretin_N_2 PF07655.13 EJS44149.1 - 0.11 13.0 20.0 0.26 11.9 20.0 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Presenilin PF01080.17 EJS44149.1 - 3.1 6.5 3.9 3 6.5 3.9 1.2 1 0 0 1 1 1 0 Presenilin Cue1_U7BR PF18499.1 EJS44150.1 - 2.9e-25 88.1 5.2 2.9e-25 88.1 5.2 1.5 2 0 0 2 2 2 1 Ubc7p-binding region of Cue1 CUE PF02845.16 EJS44150.1 - 4.2e-11 42.3 0.0 7.1e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain Pyrophosphatase PF00719.19 EJS44151.1 - 1.6e-51 174.3 0.0 2.2e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase RRM_1 PF00076.22 EJS44152.1 - 1.2e-42 143.5 2.6 1.1e-12 47.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EJS44152.1 - 7.5e-30 102.6 0.3 1.7e-26 91.8 0.1 3.7 4 0 0 4 4 4 1 Occluded RNA-recognition motif Lsm_interact PF05391.11 EJS44152.1 - 1.2e-08 34.2 1.1 3e-08 32.9 1.1 1.8 1 0 0 1 1 1 1 Lsm interaction motif Nup35_RRM_2 PF14605.6 EJS44152.1 - 3.3e-07 30.2 0.1 0.0056 16.7 0.0 2.8 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EJS44152.1 - 0.0054 17.0 2.5 0.29 11.3 0.0 4.1 3 1 1 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter DUF727 PF05303.12 EJS44152.1 - 0.0081 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Pribosyltran PF00156.27 EJS44153.1 - 7.5e-12 45.1 0.3 1e-11 44.6 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ribosomal_S17 PF00366.20 EJS44154.1 - 9.7e-24 83.3 0.4 9.7e-24 83.3 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein S17 RE_TdeIII PF09520.10 EJS44154.1 - 0.59 9.7 6.3 0.27 10.8 1.4 2.3 1 1 1 2 2 2 0 Type II restriction endonuclease, TdeIII GDC-P PF02347.16 EJS44155.1 - 1.3e-208 693.1 0.0 1.3e-196 653.5 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.20 EJS44155.1 - 0.00018 20.1 0.1 0.00064 18.4 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Helicase_Sgs1 PF11408.8 EJS44156.1 - 7.5e-33 112.4 0.1 2.1e-32 111.0 0.1 1.8 1 0 0 1 1 1 1 Sgs1 RecQ helicase RQC PF09382.10 EJS44156.1 - 1.1e-28 99.3 0.1 2.3e-28 98.3 0.1 1.5 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 EJS44156.1 - 5.2e-24 84.7 1.0 4.8e-18 65.5 0.0 3.4 3 1 1 4 4 4 2 Helicase conserved C-terminal domain DEAD PF00270.29 EJS44156.1 - 1e-21 77.5 0.1 5.8e-21 75.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EJS44156.1 - 1e-15 58.2 9.1 3.8e-15 56.4 9.1 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 EJS44156.1 - 7.5e-06 26.0 0.0 7.5e-06 26.0 0.0 4.0 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit Rhodanese PF00581.20 EJS44156.1 - 0.022 15.3 2.5 3.2 8.3 0.1 3.6 2 1 1 3 3 3 0 Rhodanese-like domain HRDC PF00570.23 EJS44156.1 - 0.092 12.8 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 HRDC domain Mitochondr_Som1 PF11093.8 EJS44157.1 - 0.17 11.9 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial export protein Som1 RabGAP-TBC PF00566.18 EJS44158.1 - 1.5e-23 83.6 2.4 1.5e-23 83.6 2.4 3.0 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Peripla_BP_2 PF01497.18 EJS44158.1 - 0.022 14.3 0.1 0.054 13.0 0.1 1.7 1 0 0 1 1 1 0 Periplasmic binding protein Pox_A_type_inc PF04508.12 EJS44158.1 - 0.29 11.1 2.8 3.5 7.6 0.6 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Rootletin PF15035.6 EJS44158.1 - 4.9 7.1 19.6 0.47 10.4 8.3 3.2 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Ribosomal_L28 PF00830.19 EJS44159.1 - 6.9e-19 67.8 1.6 1.5e-18 66.7 1.6 1.6 1 0 0 1 1 1 1 Ribosomal L28 family Apo-CIII PF05778.12 EJS44160.1 - 0.11 12.1 0.5 0.2 11.3 0.5 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Glyco_hydro_63 PF03200.16 EJS44161.1 - 9.8e-06 24.6 10.8 0.00079 18.3 0.3 5.0 4 2 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain CAF1-p150_N PF15557.6 EJS44161.1 - 0.034 14.1 0.4 0.056 13.4 0.4 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to PCNA V-SNARE_C PF12352.8 EJS44162.1 - 3.4e-22 78.5 2.4 3.4e-22 78.5 2.4 2.5 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EJS44162.1 - 7e-20 71.2 5.1 7e-20 71.2 5.1 2.7 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 EJS44162.1 - 0.00084 19.2 1.7 0.00084 19.2 1.7 2.4 2 2 0 2 2 2 1 Sec20 Use1 PF09753.9 EJS44162.1 - 0.01 15.6 8.8 0.018 14.8 8.8 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Fusion_gly PF00523.18 EJS44162.1 - 0.11 10.7 6.4 0.15 10.3 0.9 2.4 2 1 0 2 2 2 0 Fusion glycoprotein F0 Pox_EPC_I2-L1 PF12575.8 EJS44162.1 - 0.14 12.4 2.5 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 LMBR1 PF04791.16 EJS44162.1 - 0.17 10.7 5.0 0.2 10.5 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein VPS53_C PF16854.5 EJS44162.1 - 0.18 11.6 3.8 1.1 9.0 0.3 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus YqjK PF13997.6 EJS44162.1 - 0.5 10.6 0.0 0.5 10.6 0.0 2.5 3 0 0 3 3 2 0 YqjK-like protein Endonuc_Holl PF10107.9 EJS44162.1 - 0.5 10.2 5.5 0.095 12.5 1.2 2.0 2 1 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Nsp1_C PF05064.13 EJS44162.1 - 0.51 10.1 10.3 0.071 12.9 2.5 3.0 1 1 1 3 3 3 0 Nsp1-like C-terminal region Snapin_Pallidin PF14712.6 EJS44162.1 - 0.69 10.4 11.7 0.17 12.3 3.8 2.8 2 2 1 3 3 3 0 Snapin/Pallidin DUF4407 PF14362.6 EJS44162.1 - 1.8 7.8 12.5 3.7 6.8 12.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 EJS44162.1 - 3.1 8.1 9.1 0.62 10.3 4.0 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 EJS44162.1 - 8.6 6.5 11.9 2.6 8.2 3.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4410 PF14366.6 EJS44162.1 - 9.7 6.1 6.5 1.9 8.4 0.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4410) Microtub_bd PF16796.5 EJS44163.1 - 3e-10 40.2 1.3 3e-10 40.2 1.3 3.3 3 2 1 4 4 4 1 Microtubule binding Med9 PF07544.13 EJS44163.1 - 0.0055 16.8 0.7 0.0055 16.8 0.7 3.9 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 RsbU_N PF08673.10 EJS44163.1 - 0.03 14.4 2.2 3.7 7.7 0.1 3.4 3 0 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF2525 PF10733.9 EJS44163.1 - 0.087 13.1 0.3 0.3 11.4 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) Lebercilin PF15619.6 EJS44163.1 - 0.59 9.8 46.5 0.88 9.2 18.3 3.6 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF2730 PF10805.8 EJS44163.1 - 1.3 9.2 13.9 0.57 10.3 2.0 4.5 3 2 2 5 5 5 0 Protein of unknown function (DUF2730) Cytochrom_B562 PF07361.11 EJS44163.1 - 1.4 9.6 18.6 1.3 9.7 7.0 3.1 3 0 0 3 3 3 0 Cytochrome b562 CENP-F_leu_zip PF10473.9 EJS44163.1 - 1.7 8.7 45.0 0.45 10.5 16.7 3.8 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_MT_bd PF06657.13 EJS44163.1 - 1.7 9.1 25.9 0.36 11.3 4.4 4.7 2 1 3 5 5 5 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 EJS44163.1 - 7.9 5.7 24.6 18 4.6 18.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 EJS44163.1 - 8.7 5.7 41.1 1.2 8.6 22.2 2.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 Cyclin_N PF00134.23 EJS44164.1 - 7.9e-40 135.5 0.0 1.5e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Rot1 PF10681.9 EJS44165.1 - 1.5e-97 325.2 1.0 1.7e-97 325.0 1.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF4739 PF15893.5 EJS44165.1 - 0.017 14.7 0.1 0.14 11.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4739) ERG2_Sigma1R PF04622.12 EJS44166.1 - 3e-95 317.5 1.2 3.7e-95 317.2 1.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein NLE PF08154.12 EJS44166.1 - 0.095 13.2 0.0 0.24 12.0 0.0 1.6 2 0 0 2 2 2 0 NLE (NUC135) domain Porin_3 PF01459.22 EJS44167.1 - 1.1e-86 290.6 0.3 1.3e-86 290.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Inp1 PF12634.7 EJS44168.1 - 1.2e-41 142.0 0.2 1.2e-41 142.0 0.2 2.0 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 CENP-K PF11802.8 EJS44168.1 - 0.08 12.5 6.7 0.13 11.8 6.7 1.4 1 0 0 1 1 1 0 Centromere-associated protein K PFK PF00365.20 EJS44169.1 - 1.1e-181 602.5 0.3 5.6e-101 337.6 0.6 2.1 2 0 0 2 2 2 2 Phosphofructokinase GHMP_kinases_N PF00288.26 EJS44170.1 - 1.6e-19 69.9 0.4 3.8e-19 68.7 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EJS44170.1 - 1.7e-05 25.1 0.0 6.4e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal Csm1_B PF18211.1 EJS44170.1 - 0.11 12.3 0.0 0.34 10.8 0.0 1.9 1 1 0 1 1 1 0 Csm1 subunit domain B GalKase_gal_bdg PF10509.9 EJS44170.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Tubulin_3 PF14881.6 EJS44171.1 - 3.5e-24 85.5 0.1 6.3e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EJS44171.1 - 2e-20 73.3 0.9 2e-20 73.3 0.9 2.2 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EJS44171.1 - 0.0022 18.2 0.0 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain DnaJ PF00226.31 EJS44173.1 - 8.4e-26 89.9 3.6 1.3e-25 89.3 3.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EJS44173.1 - 6.6e-23 81.4 0.0 8.6e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EJS44173.1 - 6.8e-15 55.2 16.2 1.3e-14 54.3 16.2 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EJS44173.1 - 1.7e-07 31.1 7.4 1.9e-05 24.5 0.5 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_C7 PF14522.6 EJS44173.1 - 0.059 13.4 10.5 5.8 7.0 10.5 2.5 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Haem_bd PF14376.6 EJS44173.1 - 0.12 12.3 0.3 2.4 8.1 0.1 2.4 2 0 0 2 2 2 0 Haem-binding domain HypA PF01155.19 EJS44173.1 - 0.2 11.7 9.5 1.8 8.6 1.8 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EJS44173.1 - 0.56 9.9 7.9 0.25 11.0 1.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DUF1924 PF09086.11 EJS44173.1 - 0.62 10.5 3.0 2.2 8.7 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Cytochrom_C PF00034.21 EJS44173.1 - 1.3 10.3 5.2 7.1 7.9 0.0 3.0 3 0 0 3 3 3 0 Cytochrome c Cytochrom_C550 PF14495.6 EJS44173.1 - 1.4 8.6 3.9 6.2 6.5 1.3 2.3 2 0 0 2 2 2 0 Cytochrome c-550 domain Paired_CXXCH_1 PF09699.10 EJS44173.1 - 2.4 8.0 8.1 3.4 7.5 0.1 2.7 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-RING_10 PF16685.5 EJS44173.1 - 4.4 7.5 6.3 0.32 11.2 1.1 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 Cytochrome_CBB3 PF13442.6 EJS44173.1 - 9.2 6.7 18.2 0.46 10.8 0.2 3.3 2 1 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III Glyco_hydro_72 PF03198.14 EJS44174.1 - 9.8e-133 442.3 3.7 1.6e-132 441.5 3.7 1.3 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 EJS44174.1 - 0.00031 20.0 0.0 0.00057 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 EJS44174.1 - 0.0072 15.8 0.0 0.03 13.8 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3858 PF12970.7 EJS44174.1 - 0.2 11.7 0.6 0.52 10.3 0.6 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) GMP_synt_C PF00958.22 EJS44175.1 - 1.4e-44 150.1 0.0 2.6e-44 149.2 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EJS44175.1 - 3e-41 141.3 0.0 5e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EJS44175.1 - 1e-08 34.6 0.1 4.5e-05 22.7 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EJS44175.1 - 6.8e-06 26.0 0.0 4.8e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 Arginosuc_synth PF00764.19 EJS44175.1 - 0.0084 15.4 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EJS44175.1 - 0.0084 15.6 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 EJS44175.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 EJS44175.1 - 0.037 13.6 0.0 0.096 12.3 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 EJS44175.1 - 0.061 12.1 0.1 0.13 11.0 0.1 1.6 2 0 0 2 2 2 0 tRNA methyl transferase TRAPPC10 PF12584.8 EJS44176.1 - 4.5e-12 45.9 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 GHMP_kinases_N PF00288.26 EJS44177.1 - 7.1e-17 61.4 0.2 1.7e-16 60.2 0.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EJS44177.1 - 0.00076 19.8 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Uteroglobin PF01099.17 EJS44177.1 - 0.059 13.7 0.0 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 Uteroglobin family MFS_1 PF07690.16 EJS44178.1 - 2.9e-12 46.2 25.2 7.7e-07 28.4 6.8 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily DDDD PF10161.9 EJS44178.1 - 0.21 11.4 0.7 1.3 8.8 0.1 2.7 2 0 0 2 2 2 0 Putative mitochondrial precursor protein UCH PF00443.29 EJS44179.1 - 1.1e-58 198.8 3.5 1.4e-58 198.4 3.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJS44179.1 - 2.2e-21 76.8 4.5 2.2e-21 76.8 4.5 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EJS44179.1 - 4.5e-11 42.9 9.8 4.5e-11 42.9 9.8 3.0 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Cys_rich_KTR PF14205.6 EJS44179.1 - 0.077 12.8 1.7 40 4.1 0.0 3.6 3 0 0 3 3 3 0 Cysteine-rich KTR DNA_RNApol_7kD PF03604.13 EJS44179.1 - 4.1 7.2 7.4 28 4.5 2.4 2.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Mre11_DNA_bind PF04152.14 EJS44180.1 - 8.2e-49 166.2 1.2 2.3e-48 164.7 1.2 1.8 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EJS44180.1 - 8.1e-12 46.1 1.8 1.9e-11 44.9 1.8 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EcoR124_C PF12008.8 EJS44180.1 - 0.0055 16.4 1.5 0.0055 16.4 1.5 2.0 2 0 0 2 2 2 1 Type I restriction and modification enzyme - subunit R C terminal Metallophos_2 PF12850.7 EJS44180.1 - 0.071 13.3 0.0 1 9.5 0.0 2.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain UBA2_C PF16195.5 EJS44180.1 - 0.54 11.0 7.9 2.7 8.7 7.9 2.3 1 1 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus adh_short PF00106.25 EJS44181.1 - 9.8e-53 178.5 0.0 1.3e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJS44181.1 - 1.3e-33 116.5 0.1 1.6e-33 116.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJS44181.1 - 1.1e-10 41.8 0.0 1.4e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EJS44181.1 - 0.01 16.1 0.1 0.018 15.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 EJS44181.1 - 0.024 14.0 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EJS44181.1 - 0.06 12.5 0.1 0.32 10.1 0.1 2.2 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DinI PF06183.13 EJS44181.1 - 0.11 12.9 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 DinI-like family UBA_4 PF14555.6 EJS44181.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain TAFII55_N PF04658.13 EJS44182.1 - 2.4e-51 173.7 0.2 2.4e-51 173.7 0.2 3.0 2 1 0 2 2 2 1 TAFII55 protein conserved region DUF244 PF03112.14 EJS44182.1 - 0.077 12.8 0.1 0.077 12.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF RrnaAD PF00398.20 EJS44183.1 - 1.7e-80 269.9 0.0 1.9e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase S1 PF00575.23 EJS44184.1 - 2.5e-50 168.7 33.3 1.8e-12 47.4 0.6 11.7 12 1 0 12 12 12 8 S1 RNA binding domain Suf PF05843.14 EJS44184.1 - 2.9e-07 30.8 3.9 0.00033 20.7 0.0 4.9 2 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EJS44184.1 - 4.7e-05 23.8 0.0 0.9 10.1 0.0 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 EJS44184.1 - 0.00077 19.4 0.1 0.44 10.5 0.2 3.0 2 0 0 2 2 2 1 RNase II-type exonuclease C-terminal S1 domain S1_2 PF13509.6 EJS44184.1 - 0.0014 18.6 0.4 3.9 7.6 0.0 4.9 3 0 0 3 3 3 1 S1 domain TPR_14 PF13428.6 EJS44184.1 - 0.0016 19.1 0.4 4.3 8.4 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EJS44184.1 - 0.083 12.1 1.5 14 4.8 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat CsrA PF02599.16 EJS44184.1 - 0.14 12.1 1.8 7.5 6.6 0.1 3.8 4 0 0 4 4 4 0 Global regulator protein family VPS11_C PF12451.8 EJS44185.1 - 2e-12 47.1 0.1 5.7e-12 45.7 0.1 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EJS44185.1 - 1.3e-05 25.1 8.1 3.8e-05 23.6 8.1 1.8 1 1 0 1 1 1 1 Zinc-finger zf-RING_UBOX PF13445.6 EJS44185.1 - 2.7e-05 24.1 4.3 2.7e-05 24.1 4.3 2.0 2 0 0 2 2 1 1 RING-type zinc-finger Clathrin PF00637.20 EJS44185.1 - 0.0008 19.3 2.2 0.059 13.2 2.2 3.0 1 1 0 1 1 1 1 Region in Clathrin and VPS zf-RING_2 PF13639.6 EJS44185.1 - 0.0015 18.8 5.9 0.0044 17.3 5.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EJS44185.1 - 0.002 18.4 3.7 0.0048 17.2 3.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EJS44185.1 - 0.0022 17.8 6.6 0.0059 16.4 6.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJS44185.1 - 0.0031 17.4 8.8 0.008 16.1 6.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EJS44185.1 - 0.0038 17.2 1.6 0.008 16.2 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 EJS44185.1 - 0.0082 16.0 4.6 0.0082 16.0 4.6 2.1 2 0 0 2 2 2 1 PHD-finger zf-C3HC4 PF00097.25 EJS44185.1 - 0.012 15.5 7.4 0.035 14.0 7.4 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pellino PF04710.14 EJS44185.1 - 0.012 14.3 0.8 0.021 13.5 0.8 1.2 1 0 0 1 1 1 0 Pellino HPS3_N PF14761.6 EJS44185.1 - 0.021 14.4 0.1 0.09 12.3 0.1 2.2 1 1 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Zn_ribbon_17 PF17120.5 EJS44185.1 - 0.03 13.9 2.3 0.068 12.8 2.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EJS44185.1 - 0.048 13.8 6.2 0.22 11.7 6.2 2.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF5535 PF17687.1 EJS44185.1 - 0.14 12.3 0.0 0.49 10.6 0.0 1.8 2 0 0 2 2 1 0 Family of unknown function (DUF5535) FANCL_C PF11793.8 EJS44185.1 - 0.15 12.2 2.6 0.42 10.8 2.6 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 EJS44185.1 - 0.23 11.4 3.9 0.11 12.5 1.0 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 EJS44185.1 - 0.7 9.8 7.5 0.16 11.9 3.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RhoGEF PF00621.20 EJS44186.1 - 1.4e-12 48.2 8.6 1.4e-12 48.2 8.6 2.8 2 1 0 2 2 2 1 RhoGEF domain PI_PP_I PF18363.1 EJS44186.1 - 5 7.4 8.6 7.7 6.8 0.6 3.7 3 1 1 4 4 4 0 Phosphoinositide phosphatase insertion domain SWIB PF02201.18 EJS44187.1 - 6.8e-31 106.0 0.2 1.5e-30 104.9 0.2 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 EJS44187.1 - 1.8e-10 40.5 0.1 4.6e-09 36.0 0.1 2.7 2 0 0 2 2 2 1 DEK C terminal domain LisH_TPL PF17814.1 EJS44187.1 - 0.15 11.8 0.0 0.49 10.1 0.0 1.8 1 1 1 2 2 2 0 LisH-like dimerisation domain RNase_H PF00075.24 EJS44188.1 - 8.4e-36 123.3 0.0 1.6e-35 122.4 0.0 1.5 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 EJS44188.1 - 1.1e-27 96.0 8.7 7.3e-19 67.8 1.5 2.7 2 0 0 2 2 2 2 Caulimovirus viroplasmin RVT_3 PF13456.6 EJS44188.1 - 0.018 14.9 0.2 0.15 11.9 0.0 2.5 2 1 1 3 3 3 0 Reverse transcriptase-like PilM_2 PF11104.8 EJS44188.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; LRR_4 PF12799.7 EJS44189.1 - 5.8e-07 29.7 15.3 2.7 8.5 0.1 6.9 4 3 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EJS44189.1 - 2e-06 27.4 6.1 2.7 8.3 0.0 7.0 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 EJS44189.1 - 0.025 15.1 7.2 1.3e+02 3.8 0.1 6.3 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 EJS44189.1 - 0.16 11.8 13.7 17 5.3 0.1 6.0 5 2 1 6 6 6 0 Leucine rich repeat NOA36 PF06524.12 EJS44189.1 - 6.2 6.0 6.0 8.6 5.6 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein ChAPs PF09295.10 EJS44190.1 - 1e-173 577.9 4.0 1.3e-173 577.5 4.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 EJS44190.1 - 0.085 13.1 1.8 1.1 9.5 0.2 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_76 PF03663.14 EJS44191.1 - 1.1e-154 515.4 16.2 1.4e-154 515.1 16.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EJS44191.1 - 0.02 14.0 7.8 1.1 8.3 0.4 3.1 1 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 DUF382 PF04037.13 EJS44192.1 - 6.1e-52 175.1 0.0 6.1e-52 175.1 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 EJS44192.1 - 2.6e-22 78.4 1.7 4.5e-22 77.6 1.7 1.4 1 0 0 1 1 1 1 PSP Syntaxin_2 PF14523.6 EJS44192.1 - 0.0044 17.4 2.4 0.0044 17.4 2.4 2.2 2 0 0 2 2 2 1 Syntaxin-like protein PAS_10 PF13596.6 EJS44192.1 - 0.024 15.2 0.6 0.067 13.8 0.6 1.8 1 0 0 1 1 1 0 PAS domain DUF3984 PF13136.6 EJS44192.1 - 0.47 9.8 11.5 0.82 9.0 10.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) Cation_efflux PF01545.21 EJS44193.1 - 3.8e-54 183.5 4.0 5.4e-54 183.0 4.0 1.2 1 0 0 1 1 1 1 Cation efflux family SUN PF03856.13 EJS44194.1 - 2.4e-79 266.3 19.5 3e-79 266.0 19.5 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) zf-RING_2 PF13639.6 EJS44195.1 - 5.8e-07 29.7 7.3 1.3e-06 28.7 7.3 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EJS44195.1 - 1.8e-05 24.8 4.3 5e-05 23.4 4.3 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EJS44195.1 - 0.00028 21.1 6.8 0.00028 21.1 6.8 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EJS44195.1 - 0.00054 19.9 1.7 0.0012 18.9 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EJS44195.1 - 0.015 15.1 7.7 0.035 14.0 7.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJS44195.1 - 0.036 13.9 7.1 0.099 12.5 7.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EJS44195.1 - 0.05 13.9 6.8 0.11 12.8 6.8 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 EJS44195.1 - 0.061 13.2 4.9 2.6 8.0 4.9 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EJS44195.1 - 0.072 13.2 5.7 0.16 12.1 5.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EJS44195.1 - 0.079 12.8 5.5 0.7 9.7 0.9 2.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EJS44195.1 - 0.21 11.2 3.7 0.46 10.2 3.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-UDP PF14569.6 EJS44195.1 - 1.6 8.9 3.2 19 5.4 0.6 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger PHD PF00628.29 EJS44195.1 - 3.8 7.5 5.9 7.5 6.5 5.9 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 EJS44195.1 - 6.4 6.7 7.3 2.3 8.1 0.5 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Inhibitor_I34 PF10466.9 EJS44196.1 - 2.4e-38 130.6 13.8 2.6e-38 130.4 13.8 1.0 1 0 0 1 1 1 1 Saccharopepsin inhibitor I34 ARID PF01388.21 EJS44198.1 - 3.6e-19 69.2 1.0 1.1e-17 64.4 0.0 3.8 5 1 0 5 5 5 1 ARID/BRIGHT DNA binding domain JmjC PF02373.22 EJS44198.1 - 3.6e-08 33.8 0.0 0.00063 20.2 0.0 2.7 2 0 0 2 2 2 2 JmjC domain, hydroxylase PHD PF00628.29 EJS44198.1 - 6.7e-07 29.1 5.6 1.3e-06 28.2 5.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 EJS44198.1 - 1 9.5 7.5 2.2 8.4 7.5 1.6 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 EJS44198.1 - 1.4 8.8 6.6 3.4 7.6 6.6 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 EJS44198.1 - 1.8 8.8 5.5 4.8 7.5 5.5 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain MoCF_biosynth PF00994.24 EJS44199.1 - 3e-37 127.5 0.0 6.2e-37 126.5 0.0 1.5 2 0 0 2 2 2 1 Probable molybdopterin binding domain Rot1 PF10681.9 EJS44200.1 - 0.037 13.6 0.1 0.037 13.6 0.1 2.2 2 0 0 2 2 2 0 Chaperone for protein-folding within the ER, fungal XRN1_D1 PF18332.1 EJS44200.1 - 0.059 13.1 1.6 0.093 12.5 0.2 2.0 2 0 0 2 2 2 0 Exoribonuclease Xrn1 D1 domain mRNA_triPase PF02940.15 EJS44201.1 - 2.9e-41 141.6 4.1 3.9e-41 141.2 4.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Choline_kinase PF01633.20 EJS44201.1 - 0.033 13.8 3.6 3.1 7.3 3.6 2.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase Syntaxin PF00804.25 EJS44202.1 - 2e-21 76.6 19.6 2e-21 76.6 19.6 2.4 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 EJS44202.1 - 2.5e-15 56.2 1.7 2.5e-15 56.2 1.7 2.3 3 0 0 3 3 3 1 SNARE domain Synaptobrevin PF00957.21 EJS44202.1 - 0.00038 20.2 2.0 0.00038 20.2 2.0 1.9 2 0 0 2 2 2 1 Synaptobrevin DUF4085 PF13315.6 EJS44202.1 - 0.01 15.5 1.1 0.01 15.5 1.1 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF4085) DUF948 PF06103.11 EJS44202.1 - 0.012 15.9 3.9 0.012 15.9 3.9 3.7 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) SLATT_5 PF18160.1 EJS44202.1 - 0.03 13.6 0.0 0.03 13.6 0.0 2.2 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2207 PF09972.9 EJS44202.1 - 0.037 12.8 0.0 0.037 12.8 0.0 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Orthopox_B11R PF07033.11 EJS44202.1 - 0.054 13.3 2.2 5 7.0 0.1 2.7 2 0 0 2 2 2 0 Orthopoxvirus B11R protein T2SSF PF00482.23 EJS44202.1 - 0.14 12.1 2.3 0.15 12.1 0.3 2.1 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F RAMP4 PF06624.12 EJS44202.1 - 0.17 12.0 1.2 0.41 10.7 0.4 2.0 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF2277 PF10041.9 EJS44202.1 - 0.45 10.9 3.1 3 8.3 1.6 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) SlyX PF04102.12 EJS44202.1 - 1.4 9.5 13.0 0.53 10.9 3.6 3.0 2 1 1 3 3 3 0 SlyX DUF445 PF04286.12 EJS44202.1 - 4.8 6.9 18.5 7.6 6.2 6.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF445) PBP1_TM PF14812.6 EJS44202.1 - 5 7.6 11.2 0.32 11.4 0.2 2.8 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PTA_PTB PF01515.19 EJS44202.1 - 6.5 6.0 10.2 0.55 9.5 4.9 1.8 2 1 0 2 2 2 0 Phosphate acetyl/butaryl transferase DUF745 PF05335.13 EJS44202.1 - 7 6.3 20.1 0.16 11.7 11.4 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF745) RTP1_C1 PF10363.9 EJS44203.1 - 1.6e-32 112.0 0.2 1.6e-32 112.0 0.2 4.0 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EJS44203.1 - 2.4e-08 33.5 2.1 6.2e-08 32.2 2.1 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 DUF1759 PF03564.15 EJS44203.1 - 0.055 13.4 1.3 0.19 11.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Rsc14 PF08586.10 EJS44203.1 - 0.87 10.4 3.6 30 5.5 0.2 3.5 3 0 0 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit PMC2NT PF08066.12 EJS44203.1 - 1.1 9.9 5.3 1.1 10.0 2.0 3.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DnaJ PF00226.31 EJS44205.1 - 8.2e-26 89.9 1.5 1.6e-25 89.0 1.5 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EJS44205.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein PhoLip_ATPase_C PF16212.5 EJS44206.1 - 7.2e-69 232.3 25.0 7.2e-69 232.3 25.0 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EJS44206.1 - 5.7e-22 77.2 0.6 5.7e-22 77.2 0.6 3.6 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EJS44206.1 - 5.3e-13 49.7 0.1 6.1e-08 33.2 0.0 3.9 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJS44206.1 - 7.7e-11 41.9 0.0 3.8e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EJS44206.1 - 2.8e-10 40.0 0.0 9.2e-10 38.3 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EJS44206.1 - 0.0005 19.9 0.4 0.0059 16.4 0.1 2.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EJS44206.1 - 2 8.5 5.8 2.8 8.0 0.2 3.0 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Sporozoite_P67 PF05642.11 EJS44207.1 - 0.0026 15.9 4.7 0.082 11.0 1.4 2.1 2 0 0 2 2 2 2 Sporozoite P67 surface antigen LEM PF03020.15 EJS44207.1 - 0.016 14.7 0.5 0.25 11.0 0.4 2.5 2 0 0 2 2 2 0 LEM domain LisH PF08513.11 EJS44208.1 - 4.7e-07 29.5 1.2 9.9e-07 28.5 1.2 1.6 1 0 0 1 1 1 1 LisH Trypan_PARP PF05887.11 EJS44208.1 - 1.4 8.9 20.9 0.19 11.7 16.0 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) LNS2 PF08235.13 EJS44209.1 - 4.1e-95 317.6 0.0 5.9e-95 317.0 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EJS44209.1 - 1.6e-42 143.6 0.1 1e-41 141.0 0.0 2.4 3 0 0 3 3 3 1 lipin, N-terminal conserved region Aldedh PF00171.22 EJS44210.1 - 1.1e-168 561.5 0.0 1.3e-168 561.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DNA_ligase_C PF17879.1 EJS44210.1 - 0.12 12.4 0.1 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 DNA ligase C-terminal domain LuxC PF05893.14 EJS44210.1 - 0.15 11.1 0.2 0.61 9.1 0.2 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Aldedh PF00171.22 EJS44211.1 - 6.9e-169 562.2 0.0 7.8e-169 562.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EJS44211.1 - 0.16 11.4 0.0 0.53 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SPRY PF00622.28 EJS44212.1 - 2e-11 44.1 0.1 4.9e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 SPRY domain DUF1201 PF06716.11 EJS44212.1 - 0.27 11.3 1.7 0.3 11.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) COPI_assoc PF08507.10 EJS44213.1 - 1.2e-41 141.8 9.6 1.4e-41 141.6 9.6 1.0 1 0 0 1 1 1 1 COPI associated protein Gpr1_Fun34_YaaH PF01184.19 EJS44213.1 - 0.011 15.4 4.0 0.011 15.4 4.0 1.6 2 0 0 2 2 2 0 GPR1/FUN34/yaaH family Ste5_C PF12194.8 EJS44214.1 - 1.7e-83 279.3 1.4 1.7e-83 279.3 1.4 1.9 2 0 0 2 2 2 1 Protein kinase Fus3-binding Ste5 PF11610.8 EJS44214.1 - 7.6e-22 76.9 3.1 1.4e-21 76.0 3.1 1.5 1 0 0 1 1 1 1 Scaffold protein Ste5, Fus3-binding region zf-RING_2 PF13639.6 EJS44214.1 - 0.0097 16.2 2.4 0.0097 16.2 2.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EJS44214.1 - 0.072 12.8 1.2 0.18 11.5 1.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger DUF1699 PF08004.11 EJS44214.1 - 0.086 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Zn_ribbon_17 PF17120.5 EJS44214.1 - 0.22 11.2 0.8 0.44 10.2 0.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 EJS44214.1 - 0.36 10.8 1.7 0.59 10.1 0.9 1.9 1 1 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 EJS44214.1 - 3.3 7.7 4.9 13 5.9 4.9 2.1 1 1 0 1 1 1 0 zinc-RING finger domain Serinc PF03348.15 EJS44215.1 - 2e-138 462.0 17.9 2.4e-138 461.7 17.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) OCIA PF07051.11 EJS44215.1 - 0.14 12.2 1.3 2.7 8.1 0.0 2.9 2 1 1 3 3 3 0 Ovarian carcinoma immunoreactive antigen (OCIA) TMEM173 PF15009.6 EJS44215.1 - 0.21 10.7 8.0 0.025 13.7 2.5 2.0 2 0 0 2 2 2 0 Transmembrane protein 173 DUF872 PF05915.12 EJS44215.1 - 0.46 10.7 2.8 1.2 9.3 0.3 2.7 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Actin PF00022.19 EJS44216.1 - 5.1e-09 35.2 0.0 2.4e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Actin EMP70 PF02990.16 EJS44217.1 - 4.9e-188 626.0 10.9 4.9e-188 626.0 10.9 1.5 1 1 1 2 2 2 1 Endomembrane protein 70 Aminotran_1_2 PF00155.21 EJS44219.1 - 1.2e-36 126.7 0.0 1.8e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EJS44219.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Ribosomal_L34 PF00468.17 EJS44220.1 - 5.6e-20 71.0 5.3 5.6e-20 71.0 5.3 1.6 1 1 0 1 1 1 1 Ribosomal protein L34 Ribosomal_L1 PF00687.21 EJS44221.1 - 3.4e-25 89.0 0.2 4.1e-25 88.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SPG4 PF17325.2 EJS44222.1 - 2.4e-40 138.0 1.3 2.7e-40 137.9 1.3 1.0 1 0 0 1 1 1 1 Stationary phase protein 4 GEMIN8 PF15348.6 EJS44222.1 - 0.022 15.1 0.5 0.026 14.8 0.5 1.0 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 TPP_enzyme_N PF02776.18 EJS44223.1 - 4.3e-58 195.7 0.1 1.3e-56 191.0 0.1 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EJS44223.1 - 6.9e-52 175.3 0.0 6.6e-51 172.1 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EJS44223.1 - 5.8e-38 129.7 0.2 1.2e-37 128.7 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Indigoidine_A PF04227.12 EJS44223.1 - 0.0012 18.3 0.0 0.3 10.4 0.0 3.1 2 1 1 3 3 3 1 Indigoidine synthase A like protein FbpC_C_terminal PF17845.1 EJS44223.1 - 0.14 12.3 0.4 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 FbpC C-terminal regulatory nucleotide binding domain Myosin_head PF00063.21 EJS44224.1 - 1.1e-232 774.1 10.7 1.3e-232 773.8 10.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EJS44224.1 - 8.8e-50 169.0 0.3 1.9e-49 167.9 0.3 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EJS44224.1 - 7.3e-12 44.7 0.0 1.6e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJS44224.1 - 2.4e-07 30.5 0.0 6.8e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJS44224.1 - 9.4e-07 28.4 0.0 2.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Hpr_kinase_C PF07475.12 EJS44224.1 - 0.0093 15.5 0.2 5 6.6 0.0 2.8 3 0 0 3 3 3 2 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 EJS44224.1 - 0.01 16.2 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain SAP18 PF06487.12 EJS44224.1 - 0.064 13.4 0.2 1 9.5 0.0 2.6 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) AAA_22 PF13401.6 EJS44224.1 - 0.064 13.5 0.0 0.26 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EJS44224.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 EJS44224.1 - 0.086 12.8 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain IQ PF00612.27 EJS44224.1 - 0.99 9.4 14.7 2.3 8.3 6.2 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif Mur_ligase_M PF08245.12 EJS44225.1 - 7.6e-06 26.1 0.0 1.9e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain SRAP PF02586.14 EJS44226.1 - 3.3e-63 213.1 0.6 4.6e-63 212.7 0.6 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Spc24 PF08286.11 EJS44227.1 - 7.4e-23 80.8 1.8 7.4e-23 80.8 1.8 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 HIP1_clath_bdg PF16515.5 EJS44227.1 - 0.0051 17.4 1.7 0.0051 17.4 1.7 1.8 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 GrpE PF01025.19 EJS44227.1 - 0.025 14.2 3.9 0.034 13.8 3.9 1.2 1 0 0 1 1 1 0 GrpE Sdh_cyt PF01127.22 EJS44228.1 - 1.1e-25 90.0 2.7 1.1e-25 89.9 1.2 1.6 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-C3HC4_3 PF13920.6 EJS44229.1 - 3.3e-08 33.3 10.8 6.5e-08 32.3 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AICARFT_IMPCHas PF01808.18 EJS44230.1 - 1.4e-92 310.4 0.0 2.1e-92 309.7 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EJS44230.1 - 9.8e-25 86.6 0.3 2.3e-24 85.4 0.0 1.8 2 0 0 2 2 2 1 MGS-like domain Dis3l2_C_term PF17877.1 EJS44230.1 - 0.069 13.5 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Ribosomal_L15e PF00827.17 EJS44231.1 - 6.3e-90 300.0 12.1 7.8e-90 299.7 12.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 Pkr1 PF08636.10 EJS44232.1 - 3.2e-29 100.9 11.0 4e-29 100.6 11.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Acyltransferase PF01553.21 EJS44232.1 - 0.061 12.9 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase Pep_M12B_propep PF01562.19 EJS44234.1 - 0.02 15.1 0.0 0.047 13.9 0.0 1.5 1 1 0 1 1 1 0 Reprolysin family propeptide MOZ_SAS PF01853.18 EJS44235.1 - 1.5e-56 190.9 1.0 2e-56 190.5 1.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EJS44235.1 - 4.9e-07 29.3 3.4 1.4e-05 24.5 3.4 2.7 1 1 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EJS44235.1 - 0.027 14.9 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HA2 PF04408.23 EJS44236.1 - 4.7e-26 91.2 0.0 4.7e-26 91.2 0.0 2.8 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EJS44236.1 - 1.6e-13 50.8 0.0 4.7e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EJS44236.1 - 9.7e-13 48.4 0.3 1.6e-10 41.3 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJS44236.1 - 2.6e-07 30.6 0.1 7.9e-07 29.0 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EJS44236.1 - 5.3e-06 26.8 0.8 9.9e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain HTH_37 PF13744.6 EJS44236.1 - 0.00098 19.0 2.6 0.0051 16.7 0.6 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain ATPase PF06745.13 EJS44236.1 - 0.0015 18.0 2.8 0.012 15.0 0.0 2.8 3 0 0 3 3 3 1 KaiC AAA_19 PF13245.6 EJS44236.1 - 0.0028 18.0 0.0 0.0077 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EJS44236.1 - 0.0029 17.4 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EJS44236.1 - 0.013 14.9 0.1 0.081 12.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Sigma70_ner PF04546.13 EJS44236.1 - 0.021 14.7 0.2 0.021 14.7 0.2 4.7 4 0 0 4 4 3 0 Sigma-70, non-essential region BSP PF04450.12 EJS44236.1 - 0.023 14.5 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase of plants and bacteria AAA_18 PF13238.6 EJS44236.1 - 0.038 14.5 0.7 0.62 10.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EJS44236.1 - 0.058 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MFMR_assoc PF16596.5 EJS44236.1 - 0.72 10.3 5.3 1.8 9.0 5.3 1.6 1 0 0 1 1 1 0 Disordered region downstream of MFMR Hydrolase PF00702.26 EJS44238.1 - 5.6e-11 43.1 0.0 7.9e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EJS44238.1 - 6e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Abhydro_lipase PF04083.16 EJS44238.1 - 0.042 13.4 0.1 0.08 12.5 0.1 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region CAF1C_H4-bd PF12265.8 EJS44239.1 - 1.8e-15 56.9 0.1 5.1e-15 55.5 0.1 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EJS44239.1 - 2.8e-10 40.6 7.7 0.0015 19.3 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44239.1 - 2.7e-07 30.8 0.6 0.016 15.5 0.2 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ELH PF02323.15 EJS44239.1 - 0.00028 20.4 2.9 0.046 13.1 0.4 2.2 2 0 0 2 2 2 2 Egg-laying hormone precursor CLTH PF10607.9 EJS44241.1 - 5.8e-22 78.2 9.4 5.8e-22 78.2 9.4 2.3 1 1 0 2 2 2 2 CTLH/CRA C-terminal to LisH motif domain GATA PF00320.27 EJS44242.1 - 2.3e-16 59.1 3.8 4.9e-16 58.1 3.8 1.6 1 0 0 1 1 1 1 GATA zinc finger Nudix_N_2 PF14803.6 EJS44242.1 - 0.23 11.4 1.8 0.5 10.3 1.8 1.5 1 0 0 1 1 1 0 Nudix N-terminal DRMBL PF07522.14 EJS44243.1 - 5.8e-24 84.4 0.1 2.9e-23 82.2 0.0 2.1 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 EJS44243.1 - 0.22 11.5 0.0 0.89 9.5 0.0 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Arf PF00025.21 EJS44244.1 - 4.2e-54 182.6 0.2 4.8e-54 182.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EJS44244.1 - 2.4e-12 46.7 2.2 1.6e-07 30.9 0.4 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EJS44244.1 - 4.5e-11 43.0 0.0 6.4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EJS44244.1 - 4.2e-09 36.2 0.0 4.9e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EJS44244.1 - 6.3e-09 35.5 0.0 7.9e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJS44244.1 - 9.8e-07 28.9 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJS44244.1 - 2.3e-06 27.3 0.0 0.0003 20.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EJS44244.1 - 4.1e-06 26.4 0.0 5.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EJS44244.1 - 5.8e-06 26.3 0.1 0.091 12.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EJS44244.1 - 1.1e-05 25.0 0.1 8.3e-05 22.2 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 EJS44244.1 - 0.005 16.4 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EJS44244.1 - 0.0062 15.6 0.0 0.085 11.8 0.0 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 EJS44244.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 EJS44245.1 - 1e-63 215.2 0.0 1.2e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44245.1 - 2.3e-26 92.6 0.0 3.1e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJS44245.1 - 0.0029 17.6 0.1 0.043 13.7 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EJS44245.1 - 0.012 15.2 0.3 0.024 14.2 0.1 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase FAS_meander PF17951.1 EJS44245.1 - 0.035 13.9 1.4 0.06 13.2 0.6 1.6 2 0 0 2 2 2 0 Fatty acid synthase meander beta sheet domain WHIM1 PF15612.6 EJS44245.1 - 0.044 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 RICTOR_M PF14666.6 EJS44245.1 - 0.12 12.2 1.0 0.25 11.1 1.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain DUF2120 PF09893.9 EJS44246.1 - 0.058 13.5 4.4 0.09 12.9 1.1 2.4 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Tap-RNA_bind PF09162.10 EJS44246.1 - 0.089 12.6 1.8 0.5 10.2 1.8 2.2 1 1 0 1 1 1 0 Tap, RNA-binding DUF3552 PF12072.8 EJS44246.1 - 0.19 11.2 9.0 0.31 10.4 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Pyr_redox_2 PF07992.14 EJS44247.1 - 3.2e-50 171.1 0.0 4e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJS44247.1 - 6.5e-13 49.0 0.0 1.4e-11 44.7 0.0 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJS44247.1 - 0.0037 16.6 0.0 3 7.0 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase UVR PF02151.19 EJS44247.1 - 0.064 13.0 0.2 3.5 7.5 0.0 2.7 2 0 0 2 2 2 0 UvrB/uvrC motif WD40 PF00400.32 EJS44248.1 - 1.8e-24 85.6 5.9 5.3e-06 27.1 0.6 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44248.1 - 2.1e-08 34.4 0.0 0.032 14.5 0.0 5.0 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJS44248.1 - 4.3e-07 30.0 0.1 0.039 13.8 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EJS44248.1 - 0.0052 15.5 0.2 1.8 7.1 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EJS44248.1 - 0.027 13.5 0.7 7.2 5.5 0.0 3.3 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Osw5 PF17062.5 EJS44249.1 - 1.5e-29 101.9 15.1 1.9e-29 101.5 15.1 1.2 1 0 0 1 1 1 1 Outer spore wall 5 Ribophorin_II PF05817.14 EJS44250.1 - 5.2e-18 65.0 1.6 6.3e-18 64.7 1.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF2140 PF09911.9 EJS44250.1 - 0.02 14.4 0.1 0.02 14.4 0.1 1.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF4134 PF13572.6 EJS44250.1 - 0.049 13.9 1.5 8.1 6.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) Abhydrolase_9_N PF15420.6 EJS44250.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Peptidase_S24 PF00717.23 EJS44251.1 - 6.6e-06 26.0 0.0 2.1e-05 24.4 0.0 1.8 1 1 1 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.9 EJS44251.1 - 0.00074 19.3 0.0 0.0066 16.2 0.0 2.1 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 ADH_zinc_N_2 PF13602.6 EJS44252.1 - 5.4e-14 53.4 0.0 1.1e-13 52.4 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EJS44252.1 - 5.4e-07 29.6 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJS44252.1 - 0.00016 21.5 0.2 0.00032 20.5 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Nup35_RRM PF05172.13 EJS44253.1 - 5.6e-37 125.8 0.0 1.2e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EJS44253.1 - 0.00068 19.6 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PNK3P PF08645.11 EJS44254.1 - 7.5e-46 155.8 0.7 8.7e-46 155.6 0.7 1.0 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Peroxin-3 PF04882.12 EJS44255.1 - 0.081 11.9 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Peroxin-3 Ribosomal_S8 PF00410.19 EJS44256.1 - 4e-12 46.2 0.0 2.4e-11 43.7 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 E1-E2_ATPase PF00122.20 EJS44257.1 - 1.1e-36 126.1 16.2 3.1e-31 108.3 0.2 3.6 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EJS44257.1 - 3.7e-29 101.7 0.3 3.7e-29 101.7 0.3 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EJS44257.1 - 4.2e-20 72.9 0.0 2e-16 60.9 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJS44257.1 - 1e-19 70.4 0.1 1.9e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EJS44257.1 - 1.3e-14 53.6 0.0 4.5e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EJS44257.1 - 0.0033 17.2 0.6 0.0033 17.2 0.6 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ribosomal_S10 PF00338.22 EJS44258.1 - 1.2e-31 108.9 0.0 1.9e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-H2C2_2 PF13465.6 EJS44259.1 - 0.00052 20.3 5.3 0.00052 20.3 5.3 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EJS44259.1 - 0.0014 18.9 1.2 0.0014 18.9 1.2 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJS44259.1 - 0.049 14.5 15.4 0.63 11.0 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Coprogen_oxidas PF01218.18 EJS44260.1 - 9.7e-135 448.0 0.0 1.1e-134 447.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TFIIS_C PF01096.18 EJS44261.1 - 3.5e-22 78.0 2.2 3.5e-22 78.0 2.2 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EJS44261.1 - 3.6e-18 65.1 1.5 2.6e-17 62.4 0.3 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EJS44261.1 - 0.0087 16.0 4.3 0.41 10.7 0.4 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain IBR PF01485.21 EJS44261.1 - 0.17 12.1 9.5 0.99 9.7 0.2 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Baculo_LEF5_C PF11792.8 EJS44261.1 - 0.37 10.5 0.1 0.37 10.5 0.1 2.1 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-ribbon_3 PF13248.6 EJS44261.1 - 0.64 9.5 0.0 0.64 9.5 0.0 3.8 4 1 0 4 4 4 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 EJS44261.1 - 1.1 9.3 7.5 0.79 9.7 0.2 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zinc_ribbon_10 PF10058.9 EJS44261.1 - 3.2 7.5 6.9 2.9 7.7 0.1 3.1 2 1 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein UPF0547 PF10571.9 EJS44261.1 - 6.3 7.0 13.3 2.4 8.3 0.4 3.4 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 AA_permease PF00324.21 EJS44262.1 - 4.7e-135 450.9 34.4 5.9e-135 450.5 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS44262.1 - 7.8e-34 117.2 32.6 1e-33 116.9 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease TIM PF00121.18 EJS44263.1 - 2.3e-89 298.9 0.0 2.6e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase His_Phos_1 PF00300.22 EJS44264.1 - 7e-25 87.9 0.0 2.5e-14 53.4 0.0 3.1 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Dfp1_Him1_M PF08630.10 EJS44265.1 - 4.4e-43 146.5 0.0 4.4e-43 146.5 0.0 3.2 3 0 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.12 EJS44265.1 - 1e-20 73.5 0.8 2.3e-20 72.4 0.8 1.6 1 0 0 1 1 1 1 DBF zinc finger HHH_8 PF14716.6 EJS44265.1 - 0.0045 17.3 0.0 0.019 15.3 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain partial_CstF PF15861.5 EJS44265.1 - 0.25 11.2 2.3 3 7.7 1.3 2.7 2 1 1 3 3 3 0 Partial cleavage stimulation factor domain UQ_con PF00179.26 EJS44266.1 - 4.9e-45 152.6 0.1 6.5e-45 152.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Recep_L_domain PF01030.24 EJS44267.1 - 4.1e-07 30.1 14.2 0.005 17.0 0.5 4.7 1 1 4 5 5 5 4 Receptor L domain LRR_9 PF14580.6 EJS44267.1 - 0.0065 16.0 1.5 0.012 15.1 0.6 1.9 1 1 0 1 1 1 1 Leucine-rich repeat Macoilin PF09726.9 EJS44267.1 - 0.43 9.1 16.0 0.8 8.2 16.0 1.4 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 EJS44267.1 - 1.8 8.0 4.3 2.8 7.4 4.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PFU PF09070.11 EJS44268.1 - 0.00062 20.0 1.9 0.029 14.6 0.1 2.3 2 0 0 2 2 2 2 PFU (PLAA family ubiquitin binding) DUF1515 PF07439.11 EJS44268.1 - 0.041 13.9 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF3242 PF11586.8 EJS44268.1 - 0.067 12.9 0.5 0.11 12.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Palm_thioest PF02089.15 EJS44269.1 - 3.4e-07 30.4 0.1 2.2e-06 27.7 0.1 2.0 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EJS44269.1 - 6.7e-07 29.2 0.0 2.3e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EJS44269.1 - 1.3e-06 28.3 0.0 3.8e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EJS44269.1 - 5.4e-06 26.1 0.0 3.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF915 PF06028.11 EJS44269.1 - 8.9e-05 21.9 0.1 0.00088 18.7 0.0 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 EJS44269.1 - 0.0025 17.0 0.0 0.004 16.4 0.0 1.5 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EJS44269.1 - 0.0046 17.6 0.0 0.011 16.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 EJS44269.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 EJS44269.1 - 0.13 11.5 0.0 0.56 9.4 0.0 1.9 2 1 1 3 3 3 0 Serine aminopeptidase, S33 CBF PF03914.17 EJS44270.1 - 1.3e-48 165.3 0.3 1.3e-48 165.3 0.3 4.2 4 1 0 4 4 4 1 CBF/Mak21 family FliO PF04347.13 EJS44270.1 - 0.69 10.2 0.0 0.69 10.2 0.0 3.3 3 0 0 3 3 3 0 Flagellar biosynthesis protein, FliO Aminotran_1_2 PF00155.21 EJS44271.1 - 5.9e-74 249.4 0.0 7.1e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EJS44271.1 - 0.0034 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EJS44271.1 - 0.0094 14.7 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DUF3450 PF11932.8 EJS44271.1 - 0.26 10.5 0.0 0.41 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cofilin_ADF PF00241.20 EJS44272.1 - 9.1e-17 61.0 0.1 1.2e-16 60.6 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PUB PF09409.10 EJS44273.1 - 0.014 15.3 0.3 0.041 13.8 0.3 1.8 1 0 0 1 1 1 0 PUB domain RRP36 PF06102.12 EJS44273.1 - 1.4 8.8 9.2 0.66 9.9 0.8 3.0 2 2 0 2 2 2 0 rRNA biogenesis protein RRP36 Y_phosphatase2 PF03162.13 EJS44274.1 - 8e-62 207.7 1.5 1e-61 207.3 1.5 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family dsRBD2 PF17842.1 EJS44274.1 - 0.049 13.8 0.5 0.097 12.9 0.1 1.7 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 UCH PF00443.29 EJS44275.1 - 8.9e-63 212.2 0.3 8.9e-63 212.2 0.3 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJS44275.1 - 2.1e-21 76.8 0.2 2.1e-21 76.8 0.2 3.8 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EJS44275.1 - 9.5e-06 26.1 0.0 2.9e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain DUF4588 PF15251.6 EJS44275.1 - 0.44 10.3 3.0 9.1 6.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4588) Acetyltransf_1 PF00583.25 EJS44277.1 - 6.1e-24 84.5 0.0 7.6e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EJS44277.1 - 4.2e-11 42.9 0.0 5.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EJS44277.1 - 7.6e-07 29.5 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EJS44277.1 - 0.00068 19.7 0.0 0.0051 16.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EJS44277.1 - 0.0018 17.8 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 EJS44277.1 - 0.005 17.0 0.1 0.0078 16.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EJS44277.1 - 0.0083 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein PAP2_3 PF14378.6 EJS44278.1 - 2e-13 50.5 12.8 6.1e-10 39.1 3.7 2.5 2 0 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.21 EJS44278.1 - 6.8e-10 38.8 14.0 1.6e-09 37.7 8.8 3.2 2 1 0 2 2 2 1 PAP2 superfamily DUF3671 PF12420.8 EJS44278.1 - 1 9.4 5.7 0.18 11.9 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function Metallophos PF00149.28 EJS44279.1 - 4.4e-39 135.1 0.1 5.5e-39 134.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EJS44279.1 - 0.007 16.6 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain 8TM_micro PF17028.5 EJS44279.1 - 0.12 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain Glyco_hydro_65N PF03636.15 EJS44279.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Rad51 PF08423.11 EJS44280.1 - 1.8e-07 30.7 0.0 2.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 EJS44280.1 - 3.3e-07 29.9 0.2 1.4e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.6 EJS44280.1 - 0.0012 19.4 0.1 0.0012 19.4 0.1 2.3 2 1 0 3 3 3 1 AAA domain DnaB_C PF03796.15 EJS44280.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.5 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase_2 PF01637.18 EJS44280.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EJS44280.1 - 0.18 11.4 0.0 5.3 6.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain SWIM PF04434.17 EJS44282.1 - 0.0012 18.5 1.3 0.62 9.8 0.0 2.4 2 0 0 2 2 2 2 SWIM zinc finger Tfb5 PF06331.12 EJS44283.1 - 6.1e-26 90.2 0.2 7e-26 90.0 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DDE_1 PF03184.19 EJS44284.1 - 3.6e-71 238.4 3.6 8e-71 237.3 3.6 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EJS44284.1 - 2.7e-15 56.1 0.2 2.7e-15 56.1 0.2 2.5 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 EJS44284.1 - 9.5e-05 22.0 1.5 0.00022 20.9 0.2 2.4 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain DUF846 PF05832.12 EJS44285.1 - 5.4e-46 156.1 9.6 6.6e-46 155.8 9.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Gastrin PF00918.17 EJS44286.1 - 0.94 10.5 4.2 0.6 11.1 1.1 2.3 2 0 0 2 2 2 0 Gastrin/cholecystokinin family SecE PF00584.20 EJS44287.1 - 2.4e-12 46.6 0.1 3.2e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Coiled-coil_56 PF09813.9 EJS44287.1 - 0.006 16.6 0.0 0.007 16.4 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Nop52 PF05997.12 EJS44288.1 - 3.2e-71 239.6 6.0 3.9e-71 239.3 6.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.8 EJS44288.1 - 0.0065 16.6 1.0 0.022 14.9 0.3 2.1 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair DUF4611 PF15387.6 EJS44288.1 - 0.13 12.4 3.9 0.14 12.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) IFRD PF05004.13 EJS44288.1 - 0.39 9.8 0.0 0.39 9.8 0.0 2.3 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Slu7 PF11708.8 EJS44289.1 - 3.7e-15 56.4 20.6 3.7e-15 56.4 20.6 3.0 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 EJS44289.1 - 0.00012 22.0 3.1 0.00019 21.4 3.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EJS44289.1 - 0.012 15.4 1.0 0.023 14.4 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle SPX PF03105.19 EJS44290.1 - 0.031 14.2 0.1 0.031 14.2 0.1 3.3 3 1 0 4 4 4 0 SPX domain Saf_2TM PF18303.1 EJS44290.1 - 0.26 10.9 5.4 0.18 11.4 2.7 2.1 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain PQ-loop PF04193.14 EJS44291.1 - 1.5e-20 72.7 11.4 6e-18 64.4 1.8 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF1664 PF07889.12 EJS44291.1 - 0.26 11.3 1.5 9 6.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ABC2_membrane_5 PF13346.6 EJS44291.1 - 0.51 9.9 22.9 0.096 12.2 6.4 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC_tran PF00005.27 EJS44292.1 - 3.2e-37 128.1 0.0 8.8e-18 65.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 EJS44292.1 - 9.2e-15 54.2 5.3 2.2e-14 53.0 5.3 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 EJS44292.1 - 1.3e-11 44.9 8.1 0.037 13.9 0.1 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EJS44292.1 - 2.8e-09 36.7 3.8 0.015 14.8 0.6 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EJS44292.1 - 2.3e-07 31.3 0.0 0.00074 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Fer4 PF00037.27 EJS44292.1 - 3.4e-07 29.8 3.5 3.4e-07 29.8 3.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 EJS44292.1 - 2.6e-06 27.4 0.0 0.019 14.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EJS44292.1 - 5.6e-06 26.3 1.1 0.1 12.3 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 EJS44292.1 - 5.8e-06 26.8 0.1 0.024 15.1 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EJS44292.1 - 1.3e-05 25.5 0.0 0.0037 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EJS44292.1 - 5.9e-05 22.7 0.4 0.21 11.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 EJS44292.1 - 7e-05 22.8 0.7 0.41 10.6 0.1 2.8 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_30 PF13604.6 EJS44292.1 - 0.00075 19.3 0.3 0.062 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.7 EJS44292.1 - 0.00078 19.4 3.1 0.00078 19.4 3.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 EJS44292.1 - 0.0012 19.4 0.4 0.0012 19.4 0.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_23 PF13476.6 EJS44292.1 - 0.0018 18.8 4.9 0.021 15.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EJS44292.1 - 0.0019 17.4 0.0 0.62 9.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 EJS44292.1 - 0.002 18.3 0.5 0.66 10.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EJS44292.1 - 0.0026 17.5 0.2 1 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 EJS44292.1 - 0.0038 17.3 12.8 0.011 15.9 12.8 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.22 EJS44292.1 - 0.0039 17.6 0.1 1 9.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 EJS44292.1 - 0.0041 17.4 0.3 1.4 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EJS44292.1 - 0.0055 16.4 3.2 0.19 11.3 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 EJS44292.1 - 0.0055 16.6 2.4 0.23 11.4 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Fer4_2 PF12797.7 EJS44292.1 - 0.0056 16.7 0.8 0.0056 16.7 0.8 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 EJS44292.1 - 0.0066 16.5 1.6 0.0066 16.5 1.6 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EJS44292.1 - 0.0077 16.4 11.6 0.017 15.3 11.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_7 PF12775.7 EJS44292.1 - 0.0077 15.8 0.3 0.073 12.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Fer4_16 PF13484.6 EJS44292.1 - 0.012 16.5 0.2 0.012 16.5 0.2 2.7 2 1 1 3 3 1 0 4Fe-4S double cluster binding domain AAA_14 PF13173.6 EJS44292.1 - 0.014 15.4 0.9 4 7.5 0.0 3.1 4 0 0 4 4 2 0 AAA domain AAA_18 PF13238.6 EJS44292.1 - 0.015 15.9 0.0 8.4 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EJS44292.1 - 0.018 15.0 1.7 0.11 12.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EJS44292.1 - 0.025 14.6 0.1 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DLIC PF05783.11 EJS44292.1 - 0.026 13.4 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Thymidylate_kin PF02223.17 EJS44292.1 - 0.027 14.2 1.0 15 5.2 0.1 3.4 3 0 0 3 3 3 0 Thymidylate kinase MMR_HSR1 PF01926.23 EJS44292.1 - 0.029 14.4 0.1 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fer4_17 PF13534.6 EJS44292.1 - 0.054 14.1 0.2 0.054 14.1 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain VirE PF05272.11 EJS44292.1 - 0.087 12.5 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E DUF815 PF05673.13 EJS44292.1 - 0.1 11.7 0.1 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_8 PF13183.6 EJS44292.1 - 0.16 12.5 0.1 0.16 12.5 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_13 PF13166.6 EJS44292.1 - 0.16 10.6 1.0 0.42 9.2 0.0 2.1 3 0 0 3 3 3 0 AAA domain MukB PF04310.12 EJS44292.1 - 0.19 11.5 0.1 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal Zeta_toxin PF06414.12 EJS44292.1 - 0.25 10.6 0.5 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EJS44292.1 - 0.4 10.6 2.8 1.9 8.4 0.1 2.7 3 0 0 3 3 2 0 NTPase MobB PF03205.14 EJS44292.1 - 0.6 10.0 2.2 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Fer4_4 PF12800.7 EJS44292.1 - 0.96 10.1 14.9 0.45 11.2 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain JmjC PF02373.22 EJS44293.1 - 7.9e-32 110.1 1.5 1.2e-31 109.4 0.2 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 EJS44293.1 - 2.6e-08 33.7 2.7 3.4e-08 33.3 1.5 1.9 2 0 0 2 2 2 1 jmjN domain zf-H2C2_2 PF13465.6 EJS44293.1 - 5e-06 26.7 7.5 1.7e-05 25.0 6.2 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EJS44293.1 - 4.4e-05 24.0 14.3 0.025 15.4 4.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EJS44293.1 - 8.6e-05 22.8 15.3 0.025 15.0 2.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EJS44293.1 - 0.00095 19.1 9.7 0.001 19.0 3.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EJS44293.1 - 0.0043 17.1 2.6 0.011 15.8 2.6 1.7 1 0 0 1 1 1 1 Zinc ribbon domain zf_UBZ PF18439.1 EJS44293.1 - 0.28 10.8 3.0 4.2 7.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 EJS44293.1 - 0.3 11.4 9.3 0.54 10.6 4.2 2.6 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJS44293.1 - 3.6 8.1 12.8 0.85 10.1 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type MutS_V PF00488.21 EJS44294.1 - 1.6e-62 210.9 2.1 2.7e-62 210.2 1.0 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EJS44294.1 - 4.9e-35 121.5 0.8 4.9e-35 121.5 0.8 2.1 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EJS44294.1 - 9.8e-34 116.0 0.0 5e-33 113.7 0.0 2.3 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 EJS44294.1 - 5.1e-19 68.4 0.6 1.4e-18 67.0 0.6 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EJS44294.1 - 2.6e-10 40.7 0.0 9.4e-10 38.9 0.0 2.0 1 0 0 1 1 1 1 MutS domain II PRCC PF10253.9 EJS44294.1 - 0.0038 18.0 0.5 0.0038 18.0 0.5 2.4 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting AAA_27 PF13514.6 EJS44294.1 - 0.012 15.2 0.2 0.045 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EJS44294.1 - 0.08 12.7 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAHP_synth_1 PF00793.20 EJS44295.1 - 5.4e-108 360.0 0.0 6.2e-108 359.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family ECH_2 PF16113.5 EJS44296.1 - 4.5e-92 309.1 0.0 6e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EJS44296.1 - 9.9e-29 100.4 0.0 2.1e-28 99.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Sld5 PF05916.11 EJS44297.1 - 1.2e-08 35.4 0.7 2.2e-08 34.5 0.7 1.4 1 1 0 1 1 1 1 GINS complex protein PIF1 PF05970.14 EJS44297.1 - 0.011 14.9 0.1 0.029 13.5 0.0 1.6 1 1 0 2 2 2 0 PIF1-like helicase Occludin_ELL PF07303.13 EJS44297.1 - 0.036 14.8 1.3 0.036 14.8 1.3 2.2 2 1 0 2 2 2 0 Occludin homology domain IPK PF03770.16 EJS44298.1 - 4.2e-50 170.4 0.0 4.2e-50 170.4 0.0 2.2 2 1 0 2 2 2 1 Inositol polyphosphate kinase Swm2 PF17083.5 EJS44298.1 - 0.031 14.3 0.9 8.2 6.4 0.1 3.3 2 0 0 2 2 2 0 Nucleolar protein Swm2 Ribosomal_60s PF00428.19 EJS44298.1 - 0.2 12.3 2.3 0.48 11.0 2.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein FAM176 PF14851.6 EJS44298.1 - 5.2 6.7 7.3 2.8 7.6 2.6 3.0 2 0 0 2 2 2 0 FAM176 family Phage_Gp23 PF10669.9 EJS44298.1 - 8.2 6.8 7.9 33 4.8 7.9 2.0 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) GCV_T PF01571.21 EJS44299.1 - 4.1e-83 278.7 0.0 5e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EJS44299.1 - 6.1e-12 45.3 0.0 1.4e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain PRK PF00485.18 EJS44300.1 - 9.2e-12 45.1 0.3 1.3e-11 44.6 0.3 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family DEAD PF00270.29 EJS44301.1 - 7.6e-44 149.6 2.7 1.4e-43 148.7 2.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS44301.1 - 2.1e-33 115.0 1.2 2.3e-31 108.4 0.1 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS44301.1 - 7.1e-06 26.1 0.1 1.4e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EJS44301.1 - 1.8e-05 24.6 0.3 3.6e-05 23.6 0.1 1.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EJS44301.1 - 0.0002 21.7 0.3 0.0017 18.7 0.3 2.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EJS44301.1 - 0.00062 19.3 4.4 0.0019 17.7 4.4 1.8 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 EJS44301.1 - 0.0016 18.7 0.5 0.0045 17.3 0.5 1.8 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 EJS44301.1 - 0.0035 16.7 0.1 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 EJS44301.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.6 1 1 0 1 1 1 1 Helicase TniB PF05621.11 EJS44301.1 - 0.028 13.8 0.1 0.063 12.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial TniB protein CobA_CobO_BtuR PF02572.15 EJS44301.1 - 0.043 14.1 0.1 0.093 13.0 0.1 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Flavi_DEAD PF07652.14 EJS44301.1 - 0.043 13.8 0.1 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain Atg31 PF09795.9 EJS44302.1 - 1.2e-59 200.9 9.0 1.3e-59 200.7 9.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 31 tRNA-synt_2b PF00587.25 EJS44303.1 - 1.6e-31 109.7 0.0 2.9e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EJS44303.1 - 9.1e-24 83.8 8.7 9.1e-24 83.8 8.7 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain MAP7 PF05672.11 EJS44303.1 - 0.0052 16.5 0.7 0.0091 15.7 0.7 1.3 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family FapA PF03961.13 EJS44303.1 - 0.083 11.5 6.2 0.13 10.8 6.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A GED PF02212.18 EJS44303.1 - 0.45 10.7 2.6 1 9.5 2.6 1.5 1 0 0 1 1 1 0 Dynamin GTPase effector domain Myb_DNA-binding PF00249.31 EJS44304.1 - 7.2e-22 77.3 14.8 3.6e-10 39.9 0.7 4.6 3 2 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJS44304.1 - 8e-18 64.5 9.3 2.8e-12 46.7 1.2 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain DUF1376 PF07120.11 EJS44304.1 - 0.081 13.3 0.2 0.66 10.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1376) Vps54 PF07928.12 EJS44305.1 - 0.0016 18.9 0.4 0.0069 16.8 0.4 2.2 1 0 0 1 1 1 1 Vps54-like protein DUF1759 PF03564.15 EJS44305.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1759) DUF1752 PF08550.10 EJS44306.1 - 2.6e-13 49.5 2.8 6e-13 48.4 2.8 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF5428 PF17493.2 EJS44306.1 - 0.096 13.1 1.0 0.59 10.6 1.0 2.4 1 0 0 1 1 1 0 Family of unknown function (DUF5428) WD40 PF00400.32 EJS44307.1 - 1.6e-13 50.9 7.7 0.0018 19.0 0.1 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44307.1 - 1.4e-06 28.5 0.7 8.9 6.7 0.0 6.0 6 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain CX9C PF16860.5 EJS44308.1 - 3.8e-24 84.4 9.1 9e-17 60.8 0.7 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EJS44308.1 - 1.4e-08 34.6 10.7 6.4e-06 26.2 0.7 3.0 2 1 0 2 2 2 2 CHCH domain GCK PF07802.11 EJS44308.1 - 1.3e-06 28.7 6.2 0.0072 16.7 1.6 2.2 1 1 1 2 2 2 2 GCK domain UPF0203 PF05254.12 EJS44308.1 - 2e-06 27.9 8.4 0.0023 18.1 1.8 3.3 1 1 2 3 3 3 3 Uncharacterised protein family (UPF0203) NDUF_B7 PF05676.13 EJS44308.1 - 0.00036 20.2 8.1 0.024 14.3 0.3 2.9 1 1 2 3 3 3 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UCR_hinge PF02320.16 EJS44308.1 - 0.0054 16.9 1.6 0.0054 16.9 1.6 2.5 1 1 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 EJS44308.1 - 0.0086 16.1 9.6 0.17 11.9 3.0 2.6 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 EJS44308.1 - 0.0097 16.2 11.6 0.028 14.7 3.3 2.9 1 1 2 3 3 3 3 Cytochrome c oxidase assembly protein PET191 Phage_1_1 PF08200.11 EJS44308.1 - 0.012 16.0 0.1 0.065 13.7 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein COX6B PF02297.17 EJS44308.1 - 0.014 15.6 7.5 0.12 12.6 4.7 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF3715 PF12509.8 EJS44308.1 - 0.029 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) DB PF01682.19 EJS44308.1 - 0.6 10.4 7.9 4.7 7.6 7.6 2.0 1 1 0 1 1 1 0 DB module COX17 PF05051.13 EJS44308.1 - 2.6 8.4 10.0 7.9 6.9 2.5 3.0 1 1 3 4 4 4 0 Cytochrome C oxidase copper chaperone (COX17) FMN_red PF03358.15 EJS44309.1 - 3.1e-10 40.0 0.0 4.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EJS44309.1 - 0.00013 21.8 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EJS44309.1 - 0.17 12.1 0.7 1 9.6 0.6 2.2 1 1 1 2 2 2 0 Flavodoxin Fungal_trans_2 PF11951.8 EJS44310.1 - 6.6e-22 77.8 3.0 1.4e-21 76.8 3.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS44310.1 - 9.9e-07 28.8 13.0 2.1e-06 27.8 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 EJS44311.1 - 2.6e-40 137.9 0.0 4.6e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS44311.1 - 2.1e-10 40.3 0.2 3.8e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EJS44311.1 - 7.5e-10 38.6 0.0 1.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EJS44311.1 - 1.3e-05 25.3 0.0 3.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EJS44311.1 - 2.2e-05 23.8 0.0 3.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EJS44311.1 - 2.9e-05 24.4 0.1 0.0094 16.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EJS44311.1 - 0.00022 21.3 0.1 0.001 19.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EJS44311.1 - 0.00057 20.3 0.1 0.0038 17.6 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EJS44311.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EJS44311.1 - 0.0041 17.4 0.4 0.0085 16.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 EJS44311.1 - 0.011 16.3 0.5 0.055 14.0 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EJS44311.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EJS44311.1 - 0.016 15.1 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EJS44311.1 - 0.017 15.2 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EJS44311.1 - 0.018 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EJS44311.1 - 0.028 13.6 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 EJS44311.1 - 0.039 13.5 0.3 0.35 10.4 0.0 2.3 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 EJS44311.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EJS44311.1 - 0.052 13.5 0.1 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 EJS44311.1 - 0.056 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 EJS44311.1 - 0.06 12.5 0.1 0.62 9.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 EJS44311.1 - 0.067 12.5 0.0 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 EJS44311.1 - 0.08 12.4 0.2 0.46 9.9 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 EJS44311.1 - 0.099 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EJS44311.1 - 0.12 12.0 0.8 0.35 10.6 0.1 2.1 3 0 0 3 3 3 0 AAA domain PP2C PF00481.21 EJS44312.1 - 1.6e-77 260.7 0.2 3.3e-77 259.6 0.2 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EJS44312.1 - 0.0091 15.9 0.2 0.065 13.2 0.2 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Med2 PF11214.8 EJS44313.1 - 1.1e-34 118.6 3.3 1.1e-34 118.6 3.3 2.7 1 1 1 2 2 2 1 Mediator complex subunit 2 DUF3395 PF11875.8 EJS44313.1 - 4.5 7.1 13.0 0.11 12.4 5.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) ATP-synt_DE_N PF02823.16 EJS44314.1 - 3.7e-17 62.0 0.0 5.2e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Rad21_Rec8_N PF04825.13 EJS44315.1 - 3.4e-22 78.7 0.6 8.1e-22 77.5 0.3 1.8 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EJS44315.1 - 1.2e-14 53.3 0.0 2.3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein TAF6_C PF07571.13 EJS44315.1 - 0.078 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain DUF155 PF02582.14 EJS44316.1 - 1.5e-56 191.3 1.7 2.4e-56 190.6 1.7 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 EJS44316.1 - 0.027 14.9 0.0 0.072 13.6 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Trehalase PF01204.18 EJS44317.1 - 1.5e-192 641.0 0.1 1.8e-192 640.7 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EJS44317.1 - 1.7e-15 56.4 0.8 3.1e-15 55.6 0.8 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ran_BP1 PF00638.18 EJS44318.1 - 1.4e-56 190.0 2.4 2e-56 189.5 2.4 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EJS44318.1 - 5.7e-05 23.0 1.4 0.00061 19.7 1.4 2.1 1 1 0 1 1 1 1 WH1 domain PRCH PF03967.13 EJS44318.1 - 0.19 12.0 1.4 0.35 11.1 1.4 1.4 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region RCR PF12273.8 EJS44319.1 - 9.7e-30 103.7 0.1 1.4e-29 103.2 0.1 1.4 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SNARE PF05739.19 EJS44319.1 - 0.045 13.7 3.0 0.073 13.1 3.0 1.3 1 0 0 1 1 1 0 SNARE domain Tcp11 PF05794.13 EJS44320.1 - 9.9e-136 453.3 1.3 9.9e-136 453.3 1.3 1.6 2 0 0 2 2 2 1 T-complex protein 11 SRP9-21 PF05486.12 EJS44320.1 - 2.4 8.6 6.5 0.3 11.5 0.5 2.5 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) GalKase_gal_bdg PF10509.9 EJS44321.1 - 2.7e-20 71.6 0.0 5.7e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EJS44321.1 - 2.8e-12 46.7 1.1 6.7e-12 45.5 0.1 2.2 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EJS44321.1 - 2.1e-09 37.6 0.0 6e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DUF1748 PF08520.10 EJS44321.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Git3 PF11710.8 EJS44322.1 - 2e-86 288.9 7.7 3.2e-86 288.3 7.7 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EJS44322.1 - 7.3e-34 115.7 2.4 2e-33 114.3 2.4 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Nop14 PF04147.12 EJS44322.1 - 1 7.5 20.9 1.7 6.7 20.9 1.3 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 EJS44322.1 - 5.9 7.3 7.8 7.2 7.0 6.0 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 DEAD PF00270.29 EJS44323.1 - 2.2e-50 170.9 0.1 8.3e-49 165.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS44323.1 - 8.9e-23 80.7 0.1 2.6e-21 76.0 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EJS44323.1 - 3.5e-19 68.8 6.2 3.5e-19 68.8 6.2 3.7 4 0 0 4 4 4 1 DBP10CT (NUC160) domain DUF3449 PF11931.8 EJS44324.1 - 5.1e-64 215.5 0.1 5.1e-64 215.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) PRP9_N PF16958.5 EJS44324.1 - 1.6e-49 167.8 14.6 1.6e-49 167.8 14.6 2.4 2 0 0 2 2 2 1 Pre-mRNA-splicing factor PRP9 N-terminus SF3A3 PF16837.5 EJS44324.1 - 5.7e-13 49.2 1.9 5.7e-13 49.2 1.9 3.2 3 0 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 EJS44324.1 - 3.2e-10 40.0 0.5 3.1e-05 24.1 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EJS44324.1 - 7.5e-07 29.3 0.5 0.0068 16.8 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EJS44324.1 - 0.00042 20.9 6.1 0.18 12.7 0.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EJS44324.1 - 0.024 15.0 1.3 0.48 10.8 0.1 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.25 EJS44325.1 - 5.3e-52 176.8 0.0 1.2e-51 175.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44325.1 - 3.9e-22 78.8 0.0 1.4e-21 77.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EJS44325.1 - 0.00013 22.0 0.0 0.093 12.6 0.0 2.6 2 1 0 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 EJS44325.1 - 0.00017 21.3 1.5 0.13 11.9 0.0 2.8 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EJS44325.1 - 0.024 14.2 0.1 0.061 12.9 0.1 1.7 1 0 0 1 1 1 0 RIO1 family DUF4549 PF15082.6 EJS44325.1 - 0.11 12.3 0.7 0.65 9.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4549) LPD34 PF18852.1 EJS44325.1 - 0.12 12.0 1.8 0.26 10.9 0.1 2.3 2 0 0 2 2 2 0 Large polyvalent protein associated domain 34 PAP2 PF01569.21 EJS44325.1 - 0.22 11.3 0.6 0.4 10.4 0.6 1.3 1 0 0 1 1 1 0 PAP2 superfamily DUF3262 PF11660.8 EJS44326.1 - 0.096 13.1 0.9 0.21 12.0 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) NAD_Gly3P_dh_N PF01210.23 EJS44327.1 - 5e-54 182.5 0.1 7.3e-54 182.0 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EJS44327.1 - 5.6e-41 140.1 0.0 9.4e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EJS44327.1 - 0.033 14.8 0.0 11 6.7 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent His_Phos_1 PF00300.22 EJS44328.1 - 7.1e-33 113.9 0.0 3.8e-16 59.4 0.0 3.1 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) zf-C2H2 PF00096.26 EJS44329.1 - 0.023 15.1 0.2 0.023 15.1 0.2 4.0 4 1 0 4 4 4 0 Zinc finger, C2H2 type ARS2 PF04959.13 EJS44329.1 - 0.12 12.8 2.8 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Gar1 PF04410.14 EJS44329.1 - 0.3 10.9 4.7 0.9 9.3 4.7 1.8 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region zf-C2H2_6 PF13912.6 EJS44329.1 - 0.92 9.6 9.6 2.5 8.2 0.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EJS44329.1 - 1.6 9.8 0.1 1.6 9.8 0.1 4.1 5 0 0 5 5 5 0 C2H2-type zinc finger Oxysterol_BP PF01237.18 EJS44330.1 - 3.3e-135 450.7 1.0 5.9e-135 449.9 1.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 EJS44330.1 - 8.1e-12 45.6 0.1 2.5e-11 44.0 0.1 1.9 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.6 EJS44330.1 - 5.3e-11 42.5 0.3 1.3e-05 25.4 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJS44330.1 - 5.9e-10 39.6 0.2 0.00027 21.5 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EJS44330.1 - 1.2e-08 35.3 0.1 0.00029 21.3 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJS44330.1 - 3.2e-07 30.1 0.1 0.0018 18.6 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat PH_8 PF15409.6 EJS44330.1 - 4.5e-07 30.1 0.1 1.2e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Ank PF00023.30 EJS44330.1 - 1e-06 28.9 0.0 0.00038 20.8 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat PH_11 PF15413.6 EJS44330.1 - 4.2e-05 23.9 1.9 0.00023 21.5 0.6 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain EMP24_GP25L PF01105.24 EJS44331.1 - 3e-35 121.8 0.2 4e-35 121.4 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 EJS44332.1 - 3.8e-38 131.4 0.0 3.6e-21 75.7 0.0 3.4 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44332.1 - 1.7e-13 50.4 0.0 1.3e-08 34.4 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EJS44332.1 - 0.0039 17.2 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EJS44332.1 - 0.0098 14.7 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EJS44332.1 - 0.012 15.3 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EJS44332.1 - 0.017 14.4 0.0 2.5 7.3 0.0 2.5 3 0 0 3 3 3 0 Kinase-like Steroid_dh PF02544.16 EJS44333.1 - 5.5e-45 153.0 12.4 9.4e-45 152.3 12.4 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Fibrillarin PF01269.17 EJS44334.1 - 2.6e-107 357.1 0.0 3.2e-107 356.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EJS44334.1 - 1.6e-05 24.7 0.1 3e-05 23.8 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 EJS44334.1 - 0.011 15.8 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EJS44334.1 - 0.084 12.5 0.0 0.19 11.4 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EJS44334.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-C3HC4_2 PF13923.6 EJS44335.1 - 0.0062 16.4 0.2 0.016 15.0 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJS44335.1 - 0.012 15.6 0.0 0.012 15.6 0.0 1.8 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EJS44335.1 - 0.012 15.4 0.1 0.03 14.2 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EJS44335.1 - 0.016 15.2 0.3 0.04 14.0 0.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EJS44335.1 - 0.034 14.0 0.1 0.085 12.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJS44335.1 - 0.12 12.2 0.2 0.12 12.2 0.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_10 PF13374.6 EJS44335.1 - 3.8 7.5 6.1 0.62 10.0 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Glutaredoxin PF00462.24 EJS44336.1 - 2.3e-10 40.5 0.0 5.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin ExbD PF02472.16 EJS44336.1 - 0.18 12.0 1.4 0.3 11.3 1.4 1.7 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR zf-ANAPC11 PF12861.7 EJS44337.1 - 5.7e-47 157.7 6.5 7.5e-47 157.3 6.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EJS44337.1 - 9.5e-21 73.8 11.2 1.5e-20 73.2 11.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EJS44337.1 - 1.1e-05 25.6 17.1 0.00016 21.9 17.1 2.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EJS44337.1 - 0.00027 20.7 4.9 0.00027 20.7 4.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EJS44337.1 - 0.0045 16.9 13.2 0.091 12.7 14.1 2.5 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EJS44337.1 - 0.0051 16.8 10.6 0.059 13.4 8.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger DUF4942 PF13708.6 EJS44337.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) zf-C3HC4 PF00097.25 EJS44337.1 - 0.16 11.9 16.0 1.3 9.0 16.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EJS44337.1 - 0.21 11.5 12.7 13 5.8 12.7 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EJS44337.1 - 0.35 10.5 9.5 0.86 9.3 9.5 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EJS44337.1 - 0.46 10.3 15.1 0.15 11.9 2.7 3.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EJS44337.1 - 0.6 10.3 7.4 2.4 8.3 7.4 2.0 1 1 0 1 1 1 0 RING-variant domain zf-HC5HC2H_2 PF13832.6 EJS44337.1 - 1.4 9.1 8.0 0.67 10.1 4.5 2.0 1 1 1 2 2 2 0 PHD-zinc-finger like domain Rubredoxin_2 PF18073.1 EJS44337.1 - 4.1 7.2 7.3 6.5 6.6 2.7 2.7 2 0 0 2 2 2 0 Rubredoxin metal binding domain FANCL_C PF11793.8 EJS44337.1 - 5.9 7.1 16.8 1.2e+02 3.0 16.8 3.1 1 1 0 1 1 1 0 FANCL C-terminal domain IATP PF04568.12 EJS44339.1 - 3.5e-12 46.6 0.4 3.8e-12 46.5 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP TRAF_BIRC3_bd PF16673.5 EJS44339.1 - 0.0062 16.3 2.5 0.012 15.4 2.4 1.6 1 1 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain DUF2730 PF10805.8 EJS44339.1 - 0.043 13.9 1.5 0.055 13.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4140 PF13600.6 EJS44339.1 - 0.088 13.3 0.4 0.1 13.0 0.4 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Na_Ca_ex PF01699.24 EJS44341.1 - 4.1e-50 169.7 35.7 1.1e-26 93.6 8.5 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein AAA PF00004.29 EJS44342.1 - 7.8e-98 324.0 0.0 5.8e-48 162.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS44342.1 - 2.1e-23 81.8 6.3 9.9e-14 50.9 1.3 2.7 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EJS44342.1 - 6.9e-19 67.8 0.4 1.9e-18 66.4 0.4 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EJS44342.1 - 5.6e-14 52.2 0.1 1.2e-05 25.1 0.0 3.1 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EJS44342.1 - 1.1e-13 51.6 0.0 3.3e-07 30.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EJS44342.1 - 6.7e-13 49.4 0.0 8.5e-05 23.0 0.0 4.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EJS44342.1 - 1.4e-11 44.5 0.6 7.9e-06 25.9 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EJS44342.1 - 2e-11 44.2 0.0 1.1e-05 25.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EJS44342.1 - 3.5e-09 36.3 0.0 0.0016 17.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EJS44342.1 - 3.8e-09 36.2 0.0 9.3e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 EJS44342.1 - 1.1e-08 35.5 0.8 0.071 13.4 0.0 4.2 2 2 1 3 3 3 2 AAA domain RNA_helicase PF00910.22 EJS44342.1 - 2.9e-07 30.8 0.0 0.013 15.9 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 EJS44342.1 - 3.2e-07 30.5 0.0 0.026 14.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EJS44342.1 - 5.2e-07 29.2 0.5 0.037 13.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 EJS44342.1 - 6.8e-07 29.2 0.4 5.3e-05 23.1 0.0 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 EJS44342.1 - 9.4e-07 28.7 0.0 0.032 14.0 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 EJS44342.1 - 1.6e-06 27.6 0.9 0.38 10.1 0.0 3.6 2 1 0 3 3 3 2 KaiC AAA_18 PF13238.6 EJS44342.1 - 5.6e-06 26.9 0.0 0.21 12.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EJS44342.1 - 6e-06 26.1 0.1 0.089 12.5 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_7 PF12775.7 EJS44342.1 - 7.8e-06 25.5 0.1 0.071 12.6 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 EJS44342.1 - 1.3e-05 25.7 0.0 0.056 13.9 0.0 3.9 3 1 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.26 EJS44342.1 - 1.8e-05 24.5 0.1 0.21 11.3 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EJS44342.1 - 3.3e-05 23.1 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 EJS44342.1 - 4.4e-05 23.0 0.4 0.19 11.2 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_28 PF13521.6 EJS44342.1 - 5.4e-05 23.5 0.0 0.57 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EJS44342.1 - 5.7e-05 22.8 6.3 0.37 10.4 0.2 4.2 2 2 2 4 4 4 1 AAA domain Bac_DnaA PF00308.18 EJS44342.1 - 6.8e-05 22.8 0.1 0.22 11.3 0.0 3.3 4 0 0 4 4 3 1 Bacterial dnaA protein AAA_17 PF13207.6 EJS44342.1 - 0.00011 22.6 0.0 0.57 10.6 0.0 3.2 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 EJS44342.1 - 0.00015 21.1 0.0 0.14 11.2 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.11 EJS44342.1 - 0.00016 21.5 0.0 0.76 9.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EJS44342.1 - 0.00019 21.3 0.7 0.97 9.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 EJS44342.1 - 0.00034 20.6 0.0 0.6 10.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EJS44342.1 - 0.00041 20.4 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EJS44342.1 - 0.00066 19.0 0.0 1 8.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EJS44342.1 - 0.0013 18.5 0.4 2.1 8.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EJS44342.1 - 0.0014 18.6 0.1 2.2 8.1 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.6 EJS44342.1 - 0.0039 17.5 0.9 3.7 7.9 0.0 3.2 2 1 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 EJS44342.1 - 0.0089 16.0 2.9 3 7.7 0.0 3.8 3 1 0 3 3 2 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 EJS44342.1 - 0.016 15.4 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 EJS44342.1 - 0.017 14.5 0.1 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zeta_toxin PF06414.12 EJS44342.1 - 0.018 14.3 0.1 7.4 5.8 0.0 3.0 2 0 0 2 2 2 0 Zeta toxin UFD1 PF03152.14 EJS44342.1 - 0.028 13.9 0.0 0.08 12.4 0.0 1.7 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 NB-ARC PF00931.22 EJS44342.1 - 0.028 13.6 0.0 5 6.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 EJS44342.1 - 0.03 14.2 1.4 8.3 6.3 0.0 4.2 4 0 0 4 4 4 0 NTPase Zot PF05707.12 EJS44342.1 - 0.037 13.7 0.0 2.8 7.6 0.0 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) eIF-1a PF01176.19 EJS44342.1 - 0.051 13.4 0.5 0.48 10.3 0.2 2.6 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 Cytidylate_kin PF02224.18 EJS44342.1 - 0.056 13.2 0.0 8 6.1 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase KAP_NTPase PF07693.14 EJS44342.1 - 0.056 12.7 0.3 2.2 7.4 0.0 2.7 2 2 1 3 3 3 0 KAP family P-loop domain AAA_6 PF12774.7 EJS44342.1 - 0.11 11.4 0.3 5.3 5.9 0.0 2.4 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region Aldo_ket_red PF00248.21 EJS44343.1 - 1.5e-37 129.4 0.0 2.4e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Pmp3 PF01679.17 EJS44344.1 - 1.8e-21 76.1 5.6 2.5e-21 75.6 5.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Frataxin_Cyay PF01491.16 EJS44346.1 - 5.8e-36 122.8 0.0 9.5e-36 122.2 0.0 1.3 1 1 0 1 1 1 1 Frataxin-like domain Mito_carr PF00153.27 EJS44347.1 - 1.1e-49 166.2 3.1 2.3e-18 65.9 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Iwr1 PF08574.10 EJS44348.1 - 3.5e-15 56.8 11.8 3.5e-15 56.8 11.8 2.5 2 1 0 2 2 2 1 Transcription factor Iwr1 PX PF00787.24 EJS44349.1 - 9.4e-24 83.6 2.5 4.4e-23 81.4 0.0 3.0 3 0 0 3 3 3 1 PX domain HTH_16 PF12645.7 EJS44349.1 - 0.029 14.4 0.1 0.1 12.7 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Syntaxin-6_N PF09177.11 EJS44349.1 - 0.069 13.7 10.5 1 10.0 0.4 3.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF1938 PF09153.10 EJS44349.1 - 0.39 10.8 3.5 1.8 8.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1938) FTCD_C PF04961.12 EJS44349.1 - 0.72 9.6 4.2 0.42 10.4 0.5 2.2 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Lip_prot_lig_C PF10437.9 EJS44349.1 - 0.95 9.5 3.9 32 4.6 0.7 3.4 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Baculo_PEP_C PF04513.12 EJS44349.1 - 1.4 8.9 6.9 4.4 7.3 0.2 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EJS44349.1 - 7.3 7.1 12.1 47 4.5 0.4 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein SpoU_methylase PF00588.19 EJS44350.1 - 3.1e-25 89.0 0.0 6.7e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family RNase_PH PF01138.21 EJS44351.1 - 4.3e-07 30.5 0.2 7.8e-07 29.7 0.2 1.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EJS44351.1 - 4.6e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Use1 PF09753.9 EJS44352.1 - 0.0018 18.0 0.5 0.0028 17.4 0.5 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 Spc7 PF08317.11 EJS44352.1 - 0.0058 15.6 3.5 0.0067 15.3 3.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DivIC PF04977.15 EJS44352.1 - 0.15 11.8 1.5 0.2 11.4 0.2 1.8 2 0 0 2 2 2 0 Septum formation initiator Homeodomain PF00046.29 EJS44353.1 - 1.1e-17 63.6 0.5 2.8e-17 62.3 0.5 1.7 1 0 0 1 1 1 1 Homeodomain UDPGP PF01704.18 EJS44354.1 - 2.8e-45 154.7 0.0 3.6e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EJS44354.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain DNA_pol_B PF00136.21 EJS44355.1 - 6.5e-144 480.1 0.2 9.1e-144 479.6 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EJS44355.1 - 1.6e-93 313.6 1.0 3.1e-93 312.6 1.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EJS44355.1 - 6.4e-17 61.8 5.2 1.3e-16 60.8 5.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EJS44355.1 - 0.00049 19.1 1.9 0.004 16.1 0.1 2.5 1 1 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 EJS44355.1 - 0.00099 18.8 0.2 0.0035 17.1 0.0 2.0 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Pkinase PF00069.25 EJS44356.1 - 1.7e-70 237.4 0.0 2.2e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44356.1 - 3e-36 125.0 0.0 4.4e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EJS44356.1 - 2.8e-18 66.0 0.5 6.9e-18 64.8 0.5 1.7 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 EJS44356.1 - 2.7e-06 26.4 0.0 4.5e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EJS44356.1 - 4.8e-06 26.8 0.0 1.8e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 EJS44356.1 - 0.0032 16.8 5.2 1.2 8.4 0.8 3.4 2 2 1 3 3 3 1 Kinase-like YrbL-PhoP_reg PF10707.9 EJS44356.1 - 0.0051 16.3 1.5 0.014 14.9 1.5 1.7 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 EJS44356.1 - 0.0053 16.1 0.3 0.0082 15.5 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EJS44356.1 - 0.097 12.3 1.8 0.99 9.0 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ArsA_ATPase PF02374.15 EJS44357.1 - 2.9e-120 401.1 0.0 3.3e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EJS44357.1 - 1.1e-09 38.4 0.4 1.4e-08 34.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EJS44357.1 - 7.8e-09 35.7 0.0 2e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EJS44357.1 - 0.00081 18.9 1.2 0.0066 15.9 0.4 2.4 2 1 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EJS44357.1 - 0.0019 17.7 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EJS44357.1 - 0.016 14.8 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EJS44357.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EJS44357.1 - 0.045 13.5 0.1 0.44 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EJS44357.1 - 0.054 13.4 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EJS44357.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TMF_DNA_bd PF12329.8 EJS44358.1 - 0.0022 17.9 16.6 0.0022 17.9 16.6 3.9 3 1 0 3 3 3 1 TATA element modulatory factor 1 DNA binding MscS_porin PF12795.7 EJS44358.1 - 0.0027 17.3 16.3 0.0027 17.3 16.3 2.4 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain DUF3450 PF11932.8 EJS44358.1 - 0.013 14.9 13.8 0.013 14.9 13.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4055 PF13264.6 EJS44358.1 - 0.33 11.1 3.6 0.7 10.1 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Allexi_40kDa PF05549.11 EJS44358.1 - 3.3 7.1 11.9 0.24 10.9 6.4 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein Prominin PF05478.11 EJS44358.1 - 5.7 4.8 7.9 8 4.3 7.9 1.2 1 0 0 1 1 1 0 Prominin TolA_bind_tri PF16331.5 EJS44358.1 - 6.4 6.9 18.5 1.6 8.9 0.4 2.9 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF745 PF05335.13 EJS44358.1 - 7.3 6.3 17.6 0.68 9.6 5.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF4482 PF14818.6 EJS44358.1 - 9 7.2 24.4 0.73 10.7 6.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4482) KxDL PF10241.9 EJS44358.1 - 9.5 6.6 20.4 2.8 8.3 10.3 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein zf-met PF12874.7 EJS44359.1 - 4.2e-06 27.0 0.9 1.1e-05 25.7 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EJS44359.1 - 8.9e-05 22.7 1.0 0.0002 21.6 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EJS44359.1 - 0.035 15.0 0.4 0.14 13.1 0.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.12 EJS44359.1 - 0.09 12.9 0.8 0.09 12.9 0.8 2.6 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2 PF00096.26 EJS44359.1 - 0.12 12.9 1.5 0.29 11.7 1.5 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type SNRNP27 PF08648.12 EJS44359.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.0 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins RPN6_N PF18055.1 EJS44360.1 - 1.2e-36 125.6 1.5 1.2e-36 125.6 1.5 2.8 3 1 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EJS44360.1 - 1.1e-18 67.7 2.0 1.7e-18 67.1 0.0 2.4 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 EJS44360.1 - 4.3e-13 48.7 0.8 2.3e-12 46.4 0.2 2.5 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_15 PF13429.6 EJS44360.1 - 0.00018 20.8 2.5 0.0004 19.7 2.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EJS44360.1 - 0.0012 19.4 0.1 0.6 10.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJS44360.1 - 0.0073 16.6 7.0 0.03 14.6 0.4 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.9 EJS44360.1 - 0.017 14.7 0.2 0.017 14.7 0.2 2.6 2 1 1 3 3 3 0 DDRGK domain ubiquitin PF00240.23 EJS44360.1 - 0.075 12.8 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin family TPR_2 PF07719.17 EJS44360.1 - 1.6 9.0 11.7 22 5.5 0.2 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat FRB_dom PF08771.11 EJS44360.1 - 4.6 7.7 8.4 0.57 10.6 1.0 3.3 3 2 0 3 3 3 0 FKBP12-rapamycin binding domain PMT PF02366.18 EJS44361.1 - 4.9e-91 304.7 19.5 4.9e-91 304.7 19.5 2.9 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EJS44361.1 - 1.7e-63 213.8 18.4 1.7e-63 213.8 18.4 2.1 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EJS44361.1 - 1.5e-50 171.7 0.2 2.9e-50 170.7 0.2 1.4 1 0 0 1 1 1 1 MIR domain DUF5353 PF17304.2 EJS44361.1 - 4.1 7.2 6.1 2 8.2 0.3 3.2 3 1 0 3 3 3 0 Family of unknown function (DUF5353) SRP14 PF02290.15 EJS44362.1 - 1.3e-24 86.4 0.0 2.3e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle 14kD protein UBX PF00789.20 EJS44363.1 - 8.7e-22 77.1 0.0 1.9e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain Neur_chan_memb PF02932.16 EJS44363.1 - 0.49 10.4 2.9 1.7 8.7 1.6 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2418 PF10332.9 EJS44364.1 - 1.3e-19 70.5 1.0 1.3e-19 70.5 1.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Nup35_RRM PF05172.13 EJS44365.1 - 1.9e-40 136.9 0.0 5.3e-40 135.5 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EJS44365.1 - 1.3e-05 25.1 0.4 0.00021 21.2 0.4 2.3 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif LUC7 PF03194.15 EJS44366.1 - 2.4e-58 197.8 7.0 2.8e-58 197.5 7.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF1104 PF06518.11 EJS44366.1 - 0.06 13.7 2.2 1.2 9.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) DLH PF01738.18 EJS44367.1 - 8.8e-23 81.0 0.0 1.1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EJS44367.1 - 0.00043 19.8 0.0 0.009 15.5 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 EJS44367.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase 6PF2K PF01591.18 EJS44367.1 - 0.15 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Chlorophyllase PF07224.11 EJS44367.1 - 0.15 11.0 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.11 EJS44367.1 - 0.24 11.3 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal 4F5 PF04419.14 EJS44368.1 - 1.5e-08 35.4 13.6 1.5e-08 35.4 13.6 2.2 2 1 0 2 2 2 1 4F5 protein family MAJIN PF15077.6 EJS44368.1 - 9.2 6.0 9.2 9.9 5.9 9.2 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Pyr_redox_2 PF07992.14 EJS44369.1 - 2.8e-47 161.3 0.0 3.6e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EJS44369.1 - 8e-11 42.4 0.0 5.7e-09 36.4 0.0 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EJS44369.1 - 0.007 15.7 0.0 1.3 8.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EJS44369.1 - 0.18 11.8 0.0 21 5.1 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding DEAD PF00270.29 EJS44370.1 - 4.6e-35 121.0 0.0 8.8e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS44370.1 - 7.8e-27 93.8 0.3 6.7e-25 87.6 0.3 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EJS44370.1 - 6.6e-08 32.7 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.19 EJS44371.1 - 4.6e-24 84.8 6.4 5.5e-24 84.6 6.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ldh_1_C PF02866.18 EJS44372.1 - 8e-53 178.8 0.0 1.1e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EJS44372.1 - 1e-44 152.1 0.1 1.6e-44 151.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EJS44372.1 - 0.00053 20.4 0.0 0.0014 19.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EJS44372.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Vps39_1 PF10366.9 EJS44373.1 - 4.3e-34 117.0 1.1 4.3e-34 117.0 1.1 3.5 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EJS44373.1 - 1.5e-11 44.7 0.0 5e-11 43.0 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Rxt3 PF08642.10 EJS44374.1 - 2.3e-24 86.6 0.4 2.2e-22 80.2 0.0 2.7 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 BRE1 PF08647.11 EJS44375.1 - 4.7e-26 90.7 9.2 4.7e-26 90.7 9.2 6.2 4 1 2 6 6 6 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EJS44375.1 - 1.2e-07 31.5 11.7 2.2e-07 30.6 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJS44375.1 - 9.4e-07 28.6 10.0 1.8e-06 27.7 10.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EJS44375.1 - 8.2e-06 25.7 13.6 1.7e-05 24.7 13.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EJS44375.1 - 8.9e-06 25.5 12.6 8.9e-06 25.5 12.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJS44375.1 - 0.00013 21.7 14.4 0.00013 21.7 14.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJS44375.1 - 0.0013 19.1 12.2 0.0026 18.0 12.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C2H2 PF00096.26 EJS44375.1 - 0.0034 17.8 0.2 0.0034 17.8 0.2 2.7 3 0 0 3 3 2 1 Zinc finger, C2H2 type zf-RING_UBOX PF13445.6 EJS44375.1 - 0.005 16.8 10.1 0.014 15.4 10.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C2H2_jaz PF12171.8 EJS44375.1 - 0.014 15.6 1.2 0.84 10.0 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RACo_linker PF17650.1 EJS44375.1 - 0.041 13.7 0.4 2.8 7.8 0.0 3.2 2 0 0 2 2 2 0 RACo linker region Uteroglobin PF01099.17 EJS44375.1 - 0.31 11.4 7.5 9.5 6.6 0.0 3.8 3 0 0 3 3 3 0 Uteroglobin family zf-RING_6 PF14835.6 EJS44375.1 - 0.33 10.9 4.7 0.7 9.8 4.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein APG6_N PF17675.1 EJS44375.1 - 0.35 11.4 75.9 2.3 8.8 13.5 6.7 1 1 4 5 5 5 0 Apg6 coiled-coil region FYVE PF01363.21 EJS44375.1 - 3.1 8.0 14.6 50 4.1 14.7 2.5 1 1 0 1 1 1 0 FYVE zinc finger WD40_alt PF14077.6 EJS44375.1 - 3.6 7.5 7.4 2.6 8.0 0.5 3.6 2 1 1 3 3 3 0 Alternative WD40 repeat motif zf-RING_4 PF14570.6 EJS44375.1 - 3.8 7.4 10.9 8.4 6.3 10.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EJS44375.1 - 7 6.9 10.3 21 5.4 10.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1765 PF08578.10 EJS44376.1 - 4.8e-20 72.3 6.6 4.8e-20 72.3 6.6 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1765) FemAB PF02388.16 EJS44376.1 - 0.65 8.8 7.3 1.2 7.9 4.8 2.3 2 0 0 2 2 2 0 FemAB family Bap31 PF05529.12 EJS44377.1 - 4.7e-40 136.6 4.5 6.3e-40 136.2 4.5 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Osmo_CC PF08946.10 EJS44377.1 - 0.043 14.1 1.2 0.078 13.2 1.2 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil FtsX PF02687.21 EJS44377.1 - 7 7.2 7.2 2.5e+02 2.2 7.2 2.2 1 1 0 1 1 1 0 FtsX-like permease family FSH1 PF03959.13 EJS44378.1 - 0.036 13.7 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Iso_dh PF00180.20 EJS44379.1 - 1.2e-70 238.4 0.0 1.4e-70 238.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NTP_transf_6 PF06042.11 EJS44379.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase Pex19 PF04614.12 EJS44380.1 - 2.6e-61 207.5 15.4 4.4e-61 206.8 15.4 1.3 1 0 0 1 1 1 1 Pex19 protein family RsbRD_N PF14361.6 EJS44380.1 - 0.15 12.8 1.7 8.6 7.1 0.1 3.0 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain Myb_DNA-bind_3 PF12776.7 EJS44380.1 - 0.2 12.7 1.3 0.88 10.6 0.3 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4061 PF13270.6 EJS44380.1 - 0.85 10.0 5.2 8.6 6.8 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4061) L27 PF02828.16 EJS44380.1 - 1.2 9.0 4.3 18 5.2 0.3 3.4 3 1 0 3 3 3 0 L27 domain GET2 PF08690.10 EJS44380.1 - 6.9 6.2 19.6 0.8 9.3 2.5 2.5 1 1 1 3 3 3 0 GET complex subunit GET2 Ribosomal_S14 PF00253.21 EJS44381.1 - 3.9e-15 55.4 3.0 4.3e-15 55.2 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.12 EJS44381.1 - 0.083 13.2 2.8 1.9 8.9 0.3 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase RIBIOP_C PF04950.12 EJS44382.1 - 1.5e-108 362.7 0.0 2.9e-108 361.7 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EJS44382.1 - 2.8e-23 81.8 0.0 7.7e-23 80.4 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Hydrolase_4 PF12146.8 EJS44383.1 - 1.6e-08 34.1 0.0 6.9e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EJS44383.1 - 3.6e-05 24.5 0.0 5.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EJS44383.1 - 0.0052 16.4 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold AAA_31 PF13614.6 EJS44383.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_S9 PF00326.21 EJS44383.1 - 0.093 12.2 0.0 0.67 9.4 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EJS44383.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Arylesterase PF01731.20 EJS44383.1 - 0.14 12.3 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Arylesterase Ank_4 PF13637.6 EJS44384.1 - 2.4e-14 53.5 0.3 1.9e-07 31.5 0.0 3.0 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EJS44384.1 - 3.1e-12 46.5 0.1 9.6e-05 22.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJS44384.1 - 5.2e-11 43.0 0.0 0.00027 21.4 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) KilA-N PF04383.13 EJS44384.1 - 1.2e-07 31.6 3.4 2.3e-07 30.7 0.5 3.0 2 1 0 2 2 2 1 KilA-N domain Ank PF00023.30 EJS44384.1 - 2.6e-06 27.6 0.0 0.39 11.2 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EJS44384.1 - 1.4e-05 25.1 0.1 0.067 13.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat NTP_transferase PF00483.23 EJS44385.1 - 5.7e-55 186.6 0.0 7.3e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EJS44385.1 - 3.2e-10 40.6 0.0 4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EJS44385.1 - 1.8e-09 36.9 7.5 1.6e-07 30.8 2.0 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EJS44385.1 - 0.0033 17.1 4.6 0.062 13.1 0.9 3.2 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EJS44385.1 - 0.0041 16.1 0.1 0.071 12.0 0.1 2.1 2 0 0 2 2 2 1 L-fucokinase DUF4954 PF16314.5 EJS44385.1 - 0.017 13.2 1.0 0.026 12.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 EJS44385.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase MFS_1 PF07690.16 EJS44386.1 - 1.7e-14 53.6 27.3 2.6e-14 52.9 27.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Acyltransferase PF01553.21 EJS44387.1 - 1e-33 115.8 0.0 1.5e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase zf-C2H2_4 PF13894.6 EJS44388.1 - 4.9e-08 33.1 20.2 0.00076 20.1 1.1 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EJS44388.1 - 0.00048 20.0 0.4 0.00048 20.0 0.4 4.0 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 EJS44388.1 - 0.0008 19.7 1.9 0.0008 19.7 1.9 5.2 4 1 0 4 4 4 1 Zinc finger, C2H2 type Zn-C2H2_12 PF18112.1 EJS44388.1 - 0.0043 17.5 0.8 1.7 9.2 0.1 3.3 3 0 0 3 3 3 1 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 EJS44388.1 - 0.037 14.5 2.3 0.037 14.5 2.3 4.8 4 1 1 5 5 5 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EJS44388.1 - 0.04 14.2 0.1 0.04 14.2 0.1 3.4 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.14 EJS44388.1 - 0.058 13.2 5.2 0.15 11.9 0.2 3.1 2 1 0 2 2 2 0 Rad50 zinc hook motif zf-Di19 PF05605.12 EJS44388.1 - 0.13 12.5 9.7 0.18 12.1 5.1 3.4 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 EJS44388.1 - 0.15 11.9 4.8 7.5 6.5 0.2 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EJS44388.1 - 0.51 10.3 4.2 14 5.6 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 EJS44388.1 - 0.64 10.0 7.5 4.3 7.3 0.0 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_9 PF14369.6 EJS44388.1 - 1.6 9.1 4.9 8.9 6.7 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon zf-met PF12874.7 EJS44388.1 - 2.3 8.7 5.6 0.68 10.4 0.3 3.0 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 EJS44388.1 - 5.7 7.0 11.2 2.3 8.2 0.1 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Metallophos PF00149.28 EJS44389.1 - 1.4e-38 133.5 0.1 1.8e-38 133.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EJS44389.1 - 0.0008 19.8 0.3 0.0017 18.7 0.3 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EJS44389.1 - 0.04 14.1 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 EJS44389.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain E1_DerP2_DerF2 PF02221.15 EJS44390.1 - 4.6e-29 101.5 0.0 5.3e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 ML domain CHCH PF06747.13 EJS44391.1 - 3.2e-05 23.9 0.1 4.3e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 EJS44391.1 - 0.0003 20.7 0.2 0.00036 20.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like SIR2 PF02146.17 EJS44393.1 - 3.3e-67 225.8 0.0 6.4e-67 224.9 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EJS44393.1 - 1.8e-62 209.7 0.4 3.9e-62 208.6 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EJS44393.1 - 0.0024 17.6 0.0 0.65 9.7 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain NARP1 PF12569.8 EJS44394.1 - 5.7e-114 381.9 22.3 2.7e-78 264.2 1.7 2.8 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EJS44394.1 - 2.5e-10 39.6 7.0 0.17 12.1 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EJS44394.1 - 2.6e-08 34.0 1.0 1.8 9.6 0.0 6.8 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJS44394.1 - 1.9e-07 31.5 2.5 0.26 11.8 0.0 5.7 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EJS44394.1 - 2.3e-07 31.3 0.5 0.12 13.0 0.0 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EJS44394.1 - 3.6e-06 26.7 8.2 0.69 10.3 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EJS44394.1 - 6.2e-06 26.3 7.9 0.023 14.9 0.1 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EJS44394.1 - 4.2e-05 23.6 3.3 1.2 9.7 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EJS44394.1 - 0.12 12.5 8.7 0.72 10.0 0.3 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat FRG2 PF15315.6 EJS44394.1 - 0.57 10.4 5.4 0.55 10.4 4.0 1.6 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 TPR_12 PF13424.6 EJS44394.1 - 4.1 7.8 10.9 8.5 6.7 0.0 4.6 6 2 0 6 6 6 0 Tetratricopeptide repeat DUF3602 PF12223.8 EJS44395.1 - 6.8e-17 61.8 20.4 1.7e-08 34.9 4.1 4.5 3 2 1 4 4 4 4 Protein of unknown function (DUF3602) GATase_2 PF00310.21 EJS44396.1 - 3.6e-169 562.9 0.0 5.3e-169 562.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EJS44396.1 - 4.1e-157 523.0 0.0 1.8e-156 520.9 0.0 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EJS44396.1 - 8.9e-112 373.1 0.0 2.8e-109 364.9 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EJS44396.1 - 1.7e-71 239.7 3.1 3.3e-71 238.8 3.1 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 EJS44396.1 - 1e-22 80.0 0.0 1.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 EJS44396.1 - 1.3e-18 67.3 0.4 1.2e-17 64.1 0.4 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EJS44396.1 - 1.2e-08 35.0 0.0 3.3e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EJS44396.1 - 2.6e-08 34.3 1.6 1.5e-06 28.6 0.1 3.2 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EJS44396.1 - 3.7e-06 26.5 0.1 1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EJS44396.1 - 0.00012 21.5 0.5 0.11 11.7 0.1 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EJS44396.1 - 0.00048 18.9 1.2 0.00062 18.6 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EJS44396.1 - 0.00066 19.1 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EJS44396.1 - 0.001 18.4 0.1 0.0019 17.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EJS44396.1 - 0.0028 17.1 0.0 0.044 13.1 0.0 2.6 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EJS44396.1 - 0.0031 16.6 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EJS44396.1 - 0.0053 16.0 0.1 0.017 14.4 0.1 1.8 1 0 0 1 1 1 1 Thi4 family NAD_Gly3P_dh_N PF01210.23 EJS44396.1 - 0.0074 16.3 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.24 EJS44396.1 - 0.0088 15.7 0.4 0.028 14.0 0.1 2.0 2 0 0 2 2 1 1 FAD dependent oxidoreductase AdoHcyase_NAD PF00670.21 EJS44396.1 - 0.019 15.0 3.5 0.84 9.7 0.1 2.7 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATase_6 PF13522.6 EJS44396.1 - 0.061 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_binding_7 PF13241.6 EJS44396.1 - 0.086 13.3 0.4 29 5.2 0.0 3.0 3 0 0 3 3 2 0 Putative NAD(P)-binding GIDA PF01134.22 EJS44396.1 - 0.093 11.8 1.6 0.22 10.6 0.1 2.0 1 1 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EJS44396.1 - 0.1 11.9 0.2 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Rossmann-like PF10727.9 EJS44396.1 - 0.13 12.1 0.9 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Rossmann-like domain FMN_dh PF01070.18 EJS44396.1 - 0.13 11.3 1.9 0.36 9.8 0.8 2.2 3 0 0 3 3 3 0 FMN-dependent dehydrogenase 3HCDH_N PF02737.18 EJS44396.1 - 0.18 11.7 2.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 EJS44397.1 - 1.9e-64 217.9 1.7 2.3e-64 217.6 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS44397.1 - 1.8e-08 34.3 8.1 3.1e-08 33.6 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 EJS44398.1 - 2.6e-25 88.4 3.2 2.6e-25 88.4 3.2 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJS44398.1 - 6e-23 81.3 0.9 1.2e-22 80.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EJS44398.1 - 0.00014 21.4 0.0 0.001 18.6 0.0 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EJS44398.1 - 0.0002 20.8 0.2 0.00032 20.1 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EJS44398.1 - 0.00048 21.2 0.0 0.00095 20.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EJS44398.1 - 0.0044 16.4 0.1 0.0073 15.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EJS44398.1 - 0.015 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EJS44398.1 - 0.09 12.3 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2249 PF10006.9 EJS44398.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) AAA_18 PF13238.6 EJS44399.1 - 3.5e-30 105.2 0.1 4.9e-30 104.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EJS44399.1 - 3.8e-06 27.4 0.0 1.7e-05 25.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 EJS44399.1 - 0.00018 21.9 0.3 0.00066 20.0 0.1 1.9 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 EJS44399.1 - 0.00078 19.7 0.0 0.0016 18.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EJS44399.1 - 0.0014 18.9 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EJS44399.1 - 0.0019 18.6 0.0 0.0027 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 EJS44399.1 - 0.0036 16.8 0.0 0.035 13.5 0.0 2.0 1 1 1 2 2 2 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EJS44399.1 - 0.0064 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 EJS44399.1 - 0.0066 16.1 0.1 0.88 9.2 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA PF00004.29 EJS44399.1 - 0.0078 16.6 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 EJS44399.1 - 0.014 15.3 0.1 2.5 7.9 0.0 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase NTPase_1 PF03266.15 EJS44399.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.18 EJS44399.1 - 0.092 12.5 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ADK PF00406.22 EJS44399.1 - 0.14 12.3 0.1 5.3 7.1 0.0 2.2 1 1 0 2 2 2 0 Adenylate kinase AAA_5 PF07728.14 EJS44399.1 - 0.14 12.1 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NOT2_3_5 PF04153.18 EJS44400.1 - 1.7e-30 105.8 0.9 2.1e-30 105.5 0.9 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DNA_ligase_A_M PF01068.21 EJS44401.1 - 1.4e-64 217.5 0.3 2.2e-64 216.8 0.3 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EJS44401.1 - 2.9e-45 154.7 0.7 5e-45 153.9 0.2 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EJS44401.1 - 6.5e-26 90.8 0.0 2.1e-25 89.2 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EJS44401.1 - 1.3e-06 28.8 0.1 2.1e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 EJS44401.1 - 0.0059 16.6 0.6 2.4 8.3 0.1 2.7 2 0 0 2 2 2 2 DNA ligase OB-like domain ENTH PF01417.20 EJS44402.1 - 6.3e-41 139.3 0.4 1.5e-40 138.1 0.4 1.7 1 0 0 1 1 1 1 ENTH domain SAM_adeno_trans PF01887.16 EJS44402.1 - 0.096 12.1 0.4 0.35 10.3 0.3 1.9 2 0 0 2 2 2 0 S-adenosyl-l-methionine hydroxide adenosyltransferase SCAPER_N PF16501.5 EJS44402.1 - 5.3 7.1 10.1 0.16 12.0 1.0 2.8 3 0 0 3 3 3 0 S phase cyclin A-associated protein in the endoplasmic reticulum DUF2406 PF10295.9 EJS44402.1 - 9.4 7.0 11.7 4.6 8.0 0.3 3.9 2 1 1 3 3 3 0 Uncharacterised protein (DUF2406) CENP-X PF09415.10 EJS44403.1 - 1.2e-17 63.9 0.0 1.4e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X DEAD PF00270.29 EJS44404.1 - 7.4e-45 152.8 0.1 1.2e-44 152.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EJS44404.1 - 4.2e-30 104.3 0.6 8e-29 100.2 0.4 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Arcadin_1 PF18653.1 EJS44404.1 - 0.093 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Arcadin 1 Phage_integrase PF00589.22 EJS44404.1 - 0.098 12.4 0.1 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 Phage integrase family AAA_30 PF13604.6 EJS44404.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EJS44406.1 - 5.1e-08 33.5 2.4 0.23 12.4 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF870 PF05912.11 EJS44406.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) Cyclin_N PF00134.23 EJS44407.1 - 2.6e-45 153.2 0.0 6.2e-45 152.0 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EJS44407.1 - 4.2e-32 110.7 0.1 7.8e-32 109.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain MutS_V PF00488.21 EJS44408.1 - 6.4e-49 166.5 0.3 1.1e-48 165.7 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EJS44408.1 - 1.2e-16 61.5 1.2 2e-16 60.8 0.2 1.9 2 0 0 2 2 2 1 MutS domain III AAA_29 PF13555.6 EJS44408.1 - 0.053 13.3 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EJS44408.1 - 1.3 9.0 6.6 0.91 9.6 0.1 3.8 5 0 0 5 5 5 0 AAA domain Sas10 PF09368.10 EJS44409.1 - 1.3e-28 99.2 11.6 1.3e-28 99.2 11.6 2.5 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EJS44409.1 - 4.8e-06 27.1 0.0 4.8e-06 27.1 0.0 3.3 4 0 0 4 4 4 1 Sas10/Utp3/C1D family APG9 PF04109.16 EJS44410.1 - 1.2e-195 651.1 20.4 1.4e-195 650.8 20.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Nop14 PF04147.12 EJS44411.1 - 1.6e-174 582.5 69.5 1.2e-100 338.1 13.3 2.1 1 1 1 2 2 2 2 Nop14-like family PCI PF01399.27 EJS44412.1 - 1e-23 83.9 3.7 1.8e-23 83.0 0.3 2.8 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EJS44412.1 - 7.1e-15 54.8 5.1 7.1e-15 54.8 5.1 2.6 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF5099 PF17025.5 EJS44412.1 - 0.16 12.4 4.7 0.19 12.2 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5099) Ribosomal_L3 PF00297.22 EJS44412.1 - 0.32 9.9 2.2 1.2 8.0 1.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L3 DUF2013 PF09431.10 EJS44413.1 - 6.1e-42 143.1 8.5 1.3e-41 142.0 8.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) PAXNEB PF05625.11 EJS44413.1 - 0.44 9.6 3.5 0.33 10.0 0.6 2.1 2 1 1 3 3 3 0 PAXNEB protein Coatomer_WDAD PF04053.14 EJS44414.1 - 1.9e-136 455.7 1.4 2.8e-136 455.1 1.4 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EJS44414.1 - 1.3e-83 281.0 0.0 1.8e-83 280.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EJS44414.1 - 4.3e-40 135.0 15.6 2.3e-07 31.4 0.1 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44414.1 - 4.8e-14 52.4 0.2 8e-06 26.1 0.0 6.5 5 2 2 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJS44414.1 - 2.3e-06 27.6 0.3 0.015 15.2 0.0 3.9 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EJS44414.1 - 7.7e-06 24.8 6.8 0.072 11.7 0.1 4.1 1 1 2 4 4 4 3 Nucleoporin Nup120/160 SH3_10 PF17902.1 EJS44414.1 - 0.15 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 SH3 domain EspB_PE PF18625.1 EJS44414.1 - 0.57 10.7 4.7 2.1 8.9 0.1 3.3 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain ApbA_C PF08546.11 EJS44415.1 - 1.3e-27 96.5 0.0 2.3e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EJS44415.1 - 5.8e-20 71.5 0.0 8.3e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 EJS44415.1 - 0.084 12.4 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EJS44415.1 - 0.14 12.7 0.1 0.66 10.6 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cpn60_TCP1 PF00118.24 EJS44416.1 - 4.9e-145 483.9 11.0 5.5e-145 483.7 11.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BPL_N PF09825.9 EJS44417.1 - 4.5e-124 414.4 0.0 5.6e-124 414.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EJS44417.1 - 5.7e-30 103.9 0.4 4.7e-29 100.9 0.4 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EJS44417.1 - 1.3e-14 53.8 0.0 3.1e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain RNA_pol_Rpb1_1 PF04997.12 EJS44418.1 - 3.4e-114 381.4 0.0 7.1e-114 380.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EJS44418.1 - 4.9e-107 357.3 0.1 7e-107 356.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EJS44418.1 - 3.8e-78 261.4 0.1 2.9e-77 258.6 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EJS44418.1 - 1.5e-61 207.6 0.4 2.6e-61 206.8 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EJS44418.1 - 5e-47 159.7 0.0 1.4e-46 158.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EJS44418.1 - 1.5e-46 157.7 3.1 3.3e-46 156.6 3.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EJS44418.1 - 2.8e-35 120.5 0.1 7.6e-35 119.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EJS44418.1 - 1.5e-17 62.9 296.3 0.037 14.4 12.8 14.7 8 1 1 15 15 15 13 RNA polymerase Rpb1 C-terminal repeat Scm3 PF10384.9 EJS44419.1 - 7.3e-21 73.7 1.2 7.3e-21 73.7 1.2 2.4 2 0 0 2 2 2 1 Centromere protein Scm3 Bac_rhamnosid PF05592.11 EJS44419.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Arf PF00025.21 EJS44420.1 - 4.5e-78 260.7 0.0 5.2e-78 260.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EJS44420.1 - 1.7e-14 54.1 0.1 2.3e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EJS44420.1 - 2.8e-14 53.1 0.0 3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EJS44420.1 - 1.3e-13 50.8 0.0 1.5e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EJS44420.1 - 1.2e-11 44.3 1.1 8.2e-08 31.8 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EJS44420.1 - 5.5e-10 39.0 0.0 6.8e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJS44420.1 - 2e-05 24.6 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 EJS44420.1 - 0.008 15.8 0.2 0.015 14.9 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EJS44420.1 - 0.041 14.4 0.1 0.079 13.5 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EJS44420.1 - 0.045 13.9 0.5 0.09 12.9 0.5 1.8 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 EJS44420.1 - 0.047 13.0 0.2 0.075 12.3 0.2 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 EJS44420.1 - 0.06 12.9 0.1 7.5 6.1 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EJS44420.1 - 0.063 13.2 0.4 5.8 6.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain GTP_EFTU PF00009.27 EJS44420.1 - 0.081 12.5 0.0 0.25 10.8 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EJS44420.1 - 0.083 13.4 0.1 0.13 12.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EJS44420.1 - 0.088 12.7 0.1 13 5.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Rho_GDI PF02115.17 EJS44421.1 - 5.7e-63 212.2 2.8 6.7e-63 212.0 2.8 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.28 EJS44422.1 - 7.5e-34 118.0 0.5 1.3e-33 117.2 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L41 PF05162.13 EJS44423.1 - 1.2e-10 41.2 26.3 1.3e-10 41.2 26.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 Cullin PF00888.22 EJS44424.1 - 5.1e-150 501.1 13.2 6.9e-150 500.6 13.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EJS44424.1 - 4.4e-23 81.1 0.2 4.4e-23 81.1 0.2 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 EJS44424.1 - 0.031 14.6 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 0 Penicillinase repressor HTH_36 PF13730.6 EJS44424.1 - 0.034 14.1 0.1 2.2 8.3 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain IATP PF04568.12 EJS44425.1 - 1.9e-17 63.5 0.3 2.3e-17 63.2 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Fib_alpha PF08702.10 EJS44425.1 - 0.0034 17.6 0.1 0.0036 17.5 0.1 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family TRAF_BIRC3_bd PF16673.5 EJS44425.1 - 0.012 15.3 3.2 0.022 14.5 3.1 1.5 1 1 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain BLOC1_2 PF10046.9 EJS44425.1 - 0.036 14.4 1.9 0.046 14.0 1.9 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.6 EJS44425.1 - 0.04 14.4 0.4 0.05 14.0 0.4 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 EJS44425.1 - 0.052 13.3 3.8 0.075 12.8 3.8 1.3 1 0 0 1 1 1 0 Septum formation initiator PspB PF06667.12 EJS44425.1 - 0.3 11.2 1.4 0.39 10.8 1.4 1.2 1 0 0 1 1 1 0 Phage shock protein B DUF1003 PF06210.11 EJS44425.1 - 0.31 11.2 1.4 0.41 10.8 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) XhlA PF10779.9 EJS44425.1 - 0.47 10.7 4.1 0.62 10.3 4.1 1.2 1 0 0 1 1 1 0 Haemolysin XhlA FAD-oxidase_C PF02913.19 EJS44427.1 - 8.1e-65 218.9 0.0 1.1e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EJS44427.1 - 1.4e-33 115.5 0.1 3e-33 114.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain UPF0029 PF01205.19 EJS44428.1 - 2.4e-33 114.6 0.0 3.4e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 TraH_2 PF06871.11 EJS44428.1 - 0.009 15.7 0.2 1.1 8.9 0.0 2.1 1 1 0 2 2 2 2 TraH_2 zf-CCHC PF00098.23 EJS44430.1 - 5.8e-09 35.6 48.3 7.3e-06 25.8 5.0 5.7 5 1 0 5 5 5 3 Zinc knuckle CPW_WPC PF09717.10 EJS44430.1 - 3.2 8.8 17.0 0.11 13.5 4.9 3.1 1 1 1 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) FAD-oxidase_C PF02913.19 EJS44431.1 - 1.2e-59 202.0 0.3 1.6e-59 201.6 0.3 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EJS44431.1 - 3.9e-35 120.6 0.0 1.4e-34 118.8 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain RRM_1 PF00076.22 EJS44431.1 - 0.11 12.3 0.0 6.4 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hom_end_hint PF05203.16 EJS44432.1 - 2.5e-46 158.5 0.0 3e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.14 EJS44432.1 - 3.6e-45 152.6 0.0 1.3e-38 131.6 0.0 2.4 2 0 0 2 2 2 2 Homing endonuclease LAGLIDADG_3 PF14528.6 EJS44432.1 - 8.5e-08 32.4 0.0 5.1e-05 23.5 0.1 2.7 2 0 0 2 2 2 2 LAGLIDADG-like domain ArfGap PF01412.18 EJS44433.1 - 2.6e-31 108.1 0.0 7.3e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PHA_synth_III_E PF09712.10 EJS44433.1 - 0.03 13.4 1.4 0.045 12.8 1.4 1.2 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Septin PF00735.18 EJS44434.1 - 5.7e-72 242.4 8.9 8.9e-67 225.3 2.6 2.5 3 0 0 3 3 3 2 Septin AAA_33 PF13671.6 EJS44434.1 - 0.0015 18.7 0.0 0.0044 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EJS44434.1 - 0.0038 16.8 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EJS44434.1 - 0.0048 17.2 0.1 0.015 15.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EJS44434.1 - 0.0048 16.0 2.0 0.0093 15.1 0.1 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_24 PF13479.6 EJS44434.1 - 0.017 14.8 0.1 0.18 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Synaptobrevin PF00957.21 EJS44434.1 - 0.024 14.4 1.2 0.085 12.7 1.2 1.9 1 0 0 1 1 1 0 Synaptobrevin AAA PF00004.29 EJS44434.1 - 0.032 14.6 2.2 0.034 14.6 0.0 2.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EJS44434.1 - 0.038 14.4 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 EJS44434.1 - 0.041 13.8 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 EJS44434.1 - 0.049 13.1 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein GTP_EFTU PF00009.27 EJS44434.1 - 0.082 12.4 0.3 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EJS44434.1 - 0.1 13.0 0.1 1.3 9.4 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain PduV-EutP PF10662.9 EJS44434.1 - 0.11 12.2 0.0 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EJS44434.1 - 0.13 12.8 3.0 0.23 12.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EJS44434.1 - 0.2 11.7 0.0 0.2 11.7 0.0 3.4 2 2 0 2 2 1 0 Dynamin family DUF5545 PF17699.1 EJS44434.1 - 0.27 11.0 1.2 8.1 6.2 0.2 3.0 2 1 0 3 3 3 0 Family of unknown function (DUF5545) PRKG1_interact PF15898.5 EJS44434.1 - 1.4 9.9 15.3 8.9 7.3 4.5 2.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain RRM_1 PF00076.22 EJS44435.1 - 1.1e-17 63.6 0.0 6.3e-14 51.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUR7 PF06687.12 EJS44437.1 - 3.3e-45 154.3 9.2 4e-45 154.0 9.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EJS44437.1 - 0.021 14.7 12.4 0.037 13.9 12.4 1.3 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF2207 PF09972.9 EJS44437.1 - 0.68 8.6 7.4 0.094 11.5 3.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MARVEL PF01284.23 EJS44438.1 - 7e-26 91.0 14.8 1.1e-25 90.4 14.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain Penaeidin PF05927.11 EJS44438.1 - 0.014 16.2 0.2 0.028 15.1 0.2 1.6 1 0 0 1 1 1 0 Penaeidin Bunya_G2 PF03563.13 EJS44438.1 - 0.026 13.8 1.8 0.045 13.0 1.8 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 DUF5391 PF17369.2 EJS44438.1 - 0.59 10.2 8.7 0.31 11.1 5.9 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5391) Ly49 PF08391.10 EJS44438.1 - 1.2 9.5 3.7 6.5 7.2 0.0 2.7 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region Tim17 PF02466.19 EJS44439.1 - 5e-35 120.2 11.2 1.1e-34 119.1 11.2 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2613 PF11021.8 EJS44439.1 - 0.3 11.2 4.3 0.72 10.0 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) JAB PF01398.21 EJS44440.1 - 1.1e-30 106.0 0.0 2.4e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EJS44440.1 - 0.0064 16.3 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain ELFV_dehydrog PF00208.21 EJS44441.1 - 6.8e-65 219.2 0.0 1.7e-64 217.9 0.0 1.7 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EJS44441.1 - 3.7e-18 64.5 0.1 2.2e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EJS44441.1 - 0.00084 19.2 0.0 0.0097 15.8 0.0 2.3 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain RRM_1 PF00076.22 EJS44442.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EJS44442.1 - 0.017 15.2 0.0 0.048 13.8 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif SHR3_chaperone PF08229.11 EJS44443.1 - 3.8e-74 247.7 0.2 4.8e-74 247.4 0.2 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 LapA_dom PF06305.11 EJS44443.1 - 0.077 12.8 5.7 0.86 9.5 0.1 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Mucin15 PF15672.5 EJS44444.1 - 0.00016 21.3 10.4 0.0003 20.4 10.4 1.5 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 Romo1 PF10247.9 EJS44444.1 - 0.0076 16.6 0.9 0.014 15.8 0.9 1.4 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DPM2 PF07297.12 EJS44444.1 - 0.038 14.3 0.9 0.074 13.4 0.9 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Amnionless PF14828.6 EJS44444.1 - 0.085 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Amnionless Podoplanin PF05808.11 EJS44444.1 - 1.3 9.2 11.5 0.15 12.2 6.2 2.0 2 1 0 2 2 2 0 Podoplanin AA_permease_2 PF13520.6 EJS44445.1 - 2.4e-67 227.6 41.3 2.9e-67 227.4 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EJS44445.1 - 2.7e-20 72.4 35.8 4.2e-20 71.8 35.8 1.2 1 0 0 1 1 1 1 Amino acid permease Renin_r PF07850.14 EJS44445.1 - 0.22 12.1 1.2 4.8 7.9 0.2 3.2 3 0 0 3 3 3 0 Renin receptor-like protein Shisa PF13908.6 EJS44445.1 - 2.5 8.3 8.5 0.62 10.3 0.9 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Torus PF16131.5 EJS44446.1 - 2.1e-31 108.8 0.0 4.4e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 EJS44446.1 - 3.6e-07 29.9 0.1 7.7e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EJS44446.1 - 0.013 15.6 4.7 0.031 14.3 4.7 1.7 1 0 0 1 1 1 0 Zinc finger domain RRM_3 PF08777.11 EJS44446.1 - 0.014 15.4 0.4 0.03 14.4 0.2 1.7 1 1 1 2 2 2 0 RNA binding motif RRM_occluded PF16842.5 EJS44446.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-CCCH_4 PF18044.1 EJS44446.1 - 0.2 11.5 6.4 0.39 10.6 6.4 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger GLE1 PF07817.13 EJS44447.1 - 7.9e-88 293.9 0.1 7.9e-88 293.9 0.1 2.0 2 0 0 2 2 2 1 GLE1-like protein eIF3_subunit PF08597.10 EJS44447.1 - 0.013 15.4 29.2 0.023 14.6 29.2 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit WDCP PF15390.6 EJS44447.1 - 0.23 9.8 18.6 0.32 9.3 18.6 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF4746 PF15928.5 EJS44447.1 - 2 7.8 20.0 4.1 6.7 20.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Asp-B-Hydro_N PF05279.11 EJS44447.1 - 4.3 7.3 25.7 7.3 6.6 25.7 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Macoilin PF09726.9 EJS44447.1 - 7.5 5.0 30.6 13 4.2 30.6 1.4 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 EJS44447.1 - 9.3 4.9 18.8 14 4.3 18.8 1.2 1 0 0 1 1 1 0 Presenilin Porphobil_deam PF01379.20 EJS44448.1 - 2.2e-74 249.4 0.0 2.9e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EJS44448.1 - 1.1e-23 83.3 1.6 1.9e-23 82.6 1.6 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Reticulon PF02453.17 EJS44449.1 - 3.6e-24 85.5 0.7 5.6e-24 84.9 0.7 1.3 1 0 0 1 1 1 1 Reticulon tRNA_bind_2 PF13725.6 EJS44449.1 - 0.35 10.5 3.2 0.61 9.7 0.3 2.1 2 0 0 2 2 2 0 Possible tRNA binding domain DUF639 PF04842.12 EJS44449.1 - 0.41 10.0 2.8 1.6 8.1 2.8 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF639) Sel1 PF08238.12 EJS44450.1 - 5.3e-29 100.0 26.4 3.3e-05 24.4 0.2 8.0 8 1 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 EJS44450.1 - 0.27 12.0 8.4 49 4.9 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_L10 PF00466.20 EJS44451.1 - 3e-10 40.1 0.0 5.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Methyltransf_4 PF02390.17 EJS44452.1 - 4.7e-62 208.5 0.2 6.3e-62 208.1 0.2 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EJS44452.1 - 0.00017 22.2 0.0 0.00042 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJS44452.1 - 0.00092 19.0 0.0 0.0021 17.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJS44452.1 - 0.0013 18.3 0.0 0.005 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EJS44452.1 - 0.022 14.1 0.0 0.072 12.4 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EJS44452.1 - 0.025 15.3 0.0 0.071 13.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.13 EJS44452.1 - 0.14 11.7 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Histone methylation protein DOT1 Sugar_tr PF00083.24 EJS44453.1 - 3.2e-39 135.1 28.9 4.1e-39 134.7 28.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS44453.1 - 1.3e-10 40.8 33.3 5.4e-10 38.7 28.2 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily Abhydrolase_9_N PF15420.6 EJS44453.1 - 0.55 10.2 3.6 2 8.4 0.0 2.7 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Ac76 PF05814.11 EJS44453.1 - 2.3 8.3 4.9 3.4 7.7 3.1 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) Mito_carr PF00153.27 EJS44454.1 - 2.4e-33 113.9 0.1 9.8e-15 54.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec31 PF11549.8 EJS44455.1 - 6.4e-26 90.0 2.9 6.4e-26 90.0 2.9 2.6 2 0 0 2 2 2 1 Protein transport protein SEC31 WD40 PF00400.32 EJS44455.1 - 1.3e-09 38.5 15.8 0.0039 18.0 0.1 7.1 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44455.1 - 1.9e-08 34.5 5.9 0.29 11.5 0.1 4.9 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.7 EJS44455.1 - 1.5e-07 31.4 1.0 1.3e-06 28.3 0.2 2.4 1 1 1 2 2 2 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 EJS44455.1 - 3.8e-07 30.0 0.0 3.8e-07 30.0 0.0 3.3 2 1 1 3 3 3 1 Steroid receptor RNA activator (SRA1) DUF4394 PF14339.6 EJS44455.1 - 0.027 13.9 0.9 0.061 12.7 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4394) Arf PF00025.21 EJS44456.1 - 1.1e-77 259.4 0.0 1.3e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EJS44456.1 - 2.6e-14 53.5 0.1 3.5e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EJS44456.1 - 3.6e-14 52.7 0.0 4.2e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EJS44456.1 - 3e-13 49.6 0.0 3.6e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EJS44456.1 - 6.5e-12 45.3 0.9 4.2e-08 32.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EJS44456.1 - 3.5e-10 39.6 0.0 4.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJS44456.1 - 1.5e-05 25.0 0.0 2.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 EJS44456.1 - 0.008 15.8 0.2 0.015 14.9 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain cobW PF02492.19 EJS44456.1 - 0.021 14.4 0.0 6.3 6.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EJS44456.1 - 0.035 14.3 0.4 0.078 13.1 0.4 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EJS44456.1 - 0.045 13.7 0.4 4.2 7.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EJS44456.1 - 0.045 14.3 0.1 0.084 13.4 0.1 1.5 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EJS44456.1 - 0.052 13.4 0.0 6.4 6.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase 6PF2K PF01591.18 EJS44456.1 - 0.057 12.7 0.1 0.079 12.3 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.27 EJS44456.1 - 0.07 12.7 0.0 0.24 10.9 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EJS44456.1 - 0.094 13.3 0.1 0.14 12.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EJS44456.1 - 0.29 10.8 1.0 0.97 9.1 0.3 1.9 2 0 0 2 2 2 0 Thymidylate kinase Ufd2P_core PF10408.9 EJS44457.1 - 6e-199 662.7 4.1 6e-199 662.7 4.1 1.5 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 EJS44457.1 - 1e-27 96.1 1.4 3.4e-27 94.4 1.4 2.0 1 0 0 1 1 1 1 U-box domain Metallophos PF00149.28 EJS44458.1 - 7.9e-34 117.9 0.5 1.6e-33 116.9 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SUIM_assoc PF16619.5 EJS44459.1 - 0.014 15.4 3.3 0.014 15.4 3.3 2.3 2 2 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cas9_Topo PF17894.1 EJS44459.1 - 0.04 14.0 0.2 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 DUF2967 PF11179.8 EJS44459.1 - 1.5 6.8 6.0 2.5 6.1 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF5345 PF17280.2 EJS44459.1 - 5.4 7.1 5.2 6.5 6.8 2.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Ribosomal_L41 PF05162.13 EJS44460.1 - 1.2e-10 41.2 26.3 1.3e-10 41.2 26.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 Alpha-amylase PF00128.24 EJS44461.1 - 3.9e-127 424.5 0.4 7.5e-127 423.5 0.0 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EJS44461.1 - 0.00012 22.1 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 EJS44461.1 - 0.009 15.1 0.0 0.041 13.0 0.0 1.8 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase_C PF02806.18 EJS44461.1 - 0.032 14.7 0.2 0.11 13.0 0.1 1.9 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain RhoGAP PF00620.27 EJS44462.1 - 3.1e-36 124.5 0.1 1e-35 122.8 0.1 2.0 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EJS44462.1 - 6e-33 112.9 49.6 1.6e-15 57.0 4.4 4.7 4 0 0 4 4 4 4 LIM domain SID PF11778.8 EJS44463.1 - 2.3e-41 141.0 1.4 1.3e-40 138.6 1.4 2.4 1 0 0 1 1 1 1 Septation initiation 4PPT_N PF17837.1 EJS44464.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Hpt PF01627.23 EJS44465.1 - 7e-11 42.2 0.1 1e-10 41.7 0.1 1.3 1 0 0 1 1 1 1 Hpt domain PHB_acc PF05233.13 EJS44465.1 - 0.062 13.3 0.3 0.2 11.7 0.4 1.9 2 1 0 2 2 2 0 PHB accumulation regulatory domain Kin17_mid PF10357.9 EJS44465.1 - 0.15 12.0 1.3 1.9 8.4 0.0 2.3 2 1 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein RabGAP-TBC PF00566.18 EJS44466.1 - 4.9e-33 114.6 5.6 4.9e-33 114.6 5.6 4.0 4 1 1 5 5 5 2 Rab-GTPase-TBC domain DUF1451 PF07295.11 EJS44466.1 - 0.012 15.7 0.7 0.047 13.7 0.4 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain RESP18 PF14948.6 EJS44466.1 - 0.11 12.8 0.1 0.59 10.5 0.2 2.2 2 0 0 2 2 2 0 RESP18 domain LIM_bind PF01803.16 EJS44467.1 - 2e-57 194.5 0.3 3.2e-57 193.8 0.3 1.3 1 0 0 1 1 1 1 LIM-domain binding protein Ost4 PF10215.9 EJS44468.1 - 6.9e-16 57.8 3.8 7.6e-16 57.6 3.8 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase FUSC_2 PF13515.6 EJS44469.1 - 3e-09 37.1 6.5 3e-09 37.1 6.5 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 EJS44469.1 - 2.9e-05 23.3 25.2 4.7e-05 22.6 3.2 4.3 3 1 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EJS44469.1 - 0.0004 20.3 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC PF04632.12 EJS44469.1 - 0.01 14.4 4.7 0.15 10.6 0.0 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family EF-hand_14 PF17959.1 EJS44469.1 - 0.19 12.1 3.4 13 6.2 0.2 3.1 3 0 0 3 3 3 0 EF-hand domain Y_phosphatase PF00102.27 EJS44470.1 - 1.1e-54 185.6 1.8 3.5e-54 183.9 1.8 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EJS44470.1 - 9.4e-05 22.2 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EJS44470.1 - 0.00073 19.6 0.0 0.00099 19.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EJS44470.1 - 0.0059 16.7 0.0 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Myotub-related PF06602.14 EJS44470.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Mac PF12464.8 EJS44471.1 - 2.5e-14 53.2 0.1 4.5e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 EJS44471.1 - 1e-12 47.2 15.5 1.6e-09 37.1 7.7 3.2 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EJS44471.1 - 4.1e-10 39.2 12.7 1.2e-07 31.3 5.5 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4485 PF14846.6 EJS44471.1 - 0.099 12.7 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) MinC_C PF03775.16 EJS44471.1 - 0.21 11.6 4.1 2.8 8.0 1.6 2.4 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain DUF1349 PF07081.11 EJS44472.1 - 6.4e-63 211.7 0.1 7.2e-63 211.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GH43_C2 PF17851.1 EJS44472.1 - 1e-07 31.9 0.0 1.4e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF866 PF05907.13 EJS44473.1 - 2.7e-44 150.8 2.9 3.6e-44 150.4 2.9 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-FLZ PF04570.14 EJS44473.1 - 0.014 14.8 1.1 0.027 13.9 0.1 1.9 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 zf-PHD-like PF15446.6 EJS44473.1 - 0.37 10.4 3.1 16 5.1 0.0 2.7 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain Pkinase PF00069.25 EJS44474.1 - 8.9e-82 274.4 0.1 1.5e-81 273.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44474.1 - 8e-34 117.1 0.1 6.3e-33 114.1 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS44474.1 - 1.4e-13 50.9 0.1 4.8e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EJS44474.1 - 0.00047 19.0 0.0 0.001 17.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EJS44474.1 - 0.051 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CDC50 PF03381.15 EJS44475.1 - 1e-93 313.9 1.6 1.2e-93 313.6 1.6 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Y_phosphatase2 PF03162.13 EJS44476.1 - 2e-47 160.9 4.4 2.7e-37 127.9 2.9 2.4 1 1 1 2 2 2 2 Tyrosine phosphatase family G10 PF01125.17 EJS44477.1 - 1.3e-62 209.9 8.9 1.5e-62 209.7 8.9 1.0 1 0 0 1 1 1 1 G10 protein DNase_II PF03265.15 EJS44477.1 - 0.007 15.7 0.3 0.0086 15.4 0.3 1.2 1 0 0 1 1 1 1 Deoxyribonuclease II zf-C3HC4_2 PF13923.6 EJS44478.1 - 2e-11 43.5 16.9 4.4e-11 42.4 12.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EJS44478.1 - 2.4e-10 40.1 12.4 2.4e-10 40.1 12.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJS44478.1 - 2.5e-08 33.8 17.6 2e-07 30.9 11.6 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EJS44478.1 - 6.1e-08 32.4 13.1 3.4e-07 30.0 7.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 EJS44478.1 - 2.7e-07 30.2 0.0 7.6e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 SAP domain zf-RING_2 PF13639.6 EJS44478.1 - 1.5e-06 28.4 16.8 4.1e-06 27.0 11.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EJS44478.1 - 2.7e-06 27.2 17.9 2.1e-05 24.4 10.6 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_6 PF14835.6 EJS44478.1 - 3.1e-06 27.0 4.0 6.7e-06 25.9 4.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EJS44478.1 - 4.3e-06 26.8 11.5 4.3e-06 26.8 11.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EJS44478.1 - 6.4e-06 25.9 16.1 3.6e-05 23.5 9.5 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 EJS44478.1 - 0.00053 20.1 0.0 0.0038 17.4 0.0 2.5 3 0 0 3 3 3 1 U-box domain zf-rbx1 PF12678.7 EJS44478.1 - 0.00054 20.2 7.0 0.00054 20.2 7.0 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EJS44478.1 - 0.00072 19.6 4.1 0.00072 19.6 4.1 2.0 2 0 0 2 2 2 1 zinc RING finger of MSL2 Baculo_IE-1 PF05290.11 EJS44478.1 - 0.026 14.5 3.1 0.053 13.5 1.4 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) GAGA PF09237.11 EJS44478.1 - 0.032 14.0 0.7 0.032 14.0 0.7 2.4 2 0 0 2 2 2 0 GAGA factor zf-RING_4 PF14570.6 EJS44478.1 - 0.18 11.6 7.7 0.57 10.0 2.6 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-WRNIP1_ubi PF18279.1 EJS44478.1 - 0.98 10.2 6.9 0.14 12.8 0.9 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-ANAPC11 PF12861.7 EJS44478.1 - 1.8 8.7 5.4 12 6.0 2.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger XAF1_C PF18608.1 EJS44478.1 - 3.7 7.2 8.7 1.7 8.3 0.5 3.0 3 0 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain UBZ_FAAP20 PF15750.5 EJS44478.1 - 6.3 6.8 6.6 18 5.4 1.4 3.0 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Lipase_3 PF01764.25 EJS44479.1 - 2.8e-09 37.0 0.0 5.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EJS44479.1 - 0.0068 17.0 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 EJS44479.1 - 0.036 14.0 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pro_isomerase PF00160.21 EJS44480.1 - 6e-21 75.4 0.0 1.1e-20 74.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Img2 PF05046.14 EJS44481.1 - 1.9e-24 85.7 0.3 2.5e-24 85.3 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 EJS44481.1 - 0.097 13.2 1.1 0.53 10.8 1.1 2.1 1 1 0 1 1 1 0 Translation initiation factor SUI1 WD40 PF00400.32 EJS44482.1 - 2.3e-62 205.4 39.1 2.2e-12 47.3 0.3 9.1 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44482.1 - 3.1e-19 69.0 6.6 3.7e-05 23.9 0.1 5.5 3 3 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJS44482.1 - 1.2e-09 38.4 0.9 0.00014 21.9 0.0 3.7 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 EJS44482.1 - 1.1e-07 32.2 0.0 2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 EJS44482.1 - 2.3e-05 23.6 0.1 0.54 9.2 0.0 4.0 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EJS44482.1 - 3.2e-05 22.8 9.1 2.9 6.4 0.0 5.7 3 1 2 6 6 6 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 EJS44482.1 - 0.0011 18.4 1.1 0.89 8.8 0.2 3.1 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EJS44482.1 - 0.0028 17.6 0.5 3 7.9 0.1 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EJS44482.1 - 0.0037 15.9 0.0 0.23 10.0 0.1 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EJS44482.1 - 0.0063 15.3 1.2 0.86 8.3 0.6 3.5 2 1 0 2 2 2 1 Nup133 N terminal like WD40_like PF17005.5 EJS44482.1 - 0.008 15.5 0.0 3.5 6.9 0.0 3.6 4 1 0 4 4 4 1 WD40-like domain PQ-loop PF04193.14 EJS44483.1 - 1.1e-24 86.0 20.5 3.1e-14 52.5 0.8 3.4 2 1 1 3 3 3 2 PQ loop repeat DUF3215 PF11503.8 EJS44484.1 - 2.1e-25 88.4 0.2 2.4e-25 88.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) PI31_Prot_C PF08577.11 EJS44485.1 - 1.2e-06 29.6 9.2 1.2e-06 29.6 9.2 2.1 2 0 0 2 2 2 1 PI31 proteasome regulator PAT1 PF09770.9 EJS44486.1 - 1.1e-76 258.9 33.2 3.9e-66 224.0 18.2 4.6 1 1 0 2 2 2 2 Topoisomerase II-associated protein PAT1 PP2C PF00481.21 EJS44487.1 - 2.1e-43 148.8 0.0 5e-43 147.6 0.0 1.6 1 1 1 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EJS44487.1 - 8.2e-05 22.3 0.0 0.00082 19.1 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C Med12 PF09497.10 EJS44488.1 - 1.3e-18 67.0 0.1 3.1e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Blo-t-5 PF11642.8 EJS44488.1 - 0.024 14.6 1.3 0.077 13.0 0.2 2.5 2 0 0 2 2 2 0 Mite allergen Blo t 5 YqzH PF14164.6 EJS44488.1 - 0.025 14.6 0.0 0.12 12.4 0.0 2.3 1 0 0 1 1 1 0 YqzH-like protein DUF4646 PF15496.6 EJS44489.1 - 0.023 15.3 0.1 0.036 14.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) RET_CLD3 PF17812.1 EJS44489.1 - 0.033 14.4 0.3 0.048 13.9 0.3 1.4 1 1 0 1 1 1 0 RET Cadherin like domain 3 Thioredoxin PF00085.20 EJS44490.1 - 5e-30 103.5 0.1 6.1e-30 103.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EJS44490.1 - 5.4e-05 23.6 0.2 0.00013 22.3 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EJS44490.1 - 0.00013 22.2 0.0 0.005 17.2 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EJS44490.1 - 0.00065 19.6 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EJS44490.1 - 0.0022 17.7 0.0 0.0025 17.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EJS44490.1 - 0.0052 16.5 0.1 0.017 14.8 0.1 1.6 1 1 1 2 2 2 1 Redoxin Phosducin PF02114.16 EJS44490.1 - 0.0072 15.3 0.0 0.008 15.1 0.0 1.0 1 0 0 1 1 1 1 Phosducin DSBA PF01323.20 EJS44490.1 - 0.011 15.5 0.2 0.23 11.2 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TraF PF13728.6 EJS44490.1 - 0.011 15.6 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EJS44490.1 - 0.025 14.8 0.1 0.037 14.2 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 EJS44490.1 - 0.084 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family WD40 PF00400.32 EJS44491.1 - 5.7e-51 169.4 13.1 1e-08 35.7 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EJS44491.1 - 2.5e-28 98.2 12.0 2.5e-28 98.2 12.0 2.4 2 0 0 2 2 2 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EJS44491.1 - 1.8e-16 60.2 0.1 6.9e-06 26.3 0.0 6.1 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJS44491.1 - 7.7e-05 21.5 7.6 0.14 10.7 0.1 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EJS44491.1 - 0.00011 21.7 0.1 0.32 10.3 0.0 4.3 3 1 2 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 EJS44491.1 - 0.00048 19.2 0.3 0.64 8.9 0.0 3.9 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein FSA_C PF10479.9 EJS44491.1 - 4.7 5.2 11.7 0.058 11.5 3.8 1.7 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Csm1_N PF18504.1 EJS44492.1 - 7.4e-26 90.3 7.0 7.4e-26 90.3 7.0 2.0 2 0 0 2 2 2 1 Csm1 N-terminal domain Csm1 PF12539.8 EJS44492.1 - 1e-21 77.4 0.1 1.6e-21 76.7 0.1 1.3 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 ADIP PF11559.8 EJS44492.1 - 0.00054 20.1 1.3 0.0011 19.0 1.3 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Tmemb_cc2 PF10267.9 EJS44492.1 - 0.00097 18.4 0.9 0.00098 18.4 0.1 1.4 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein DUF4407 PF14362.6 EJS44492.1 - 0.002 17.5 0.4 0.0029 17.0 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 EJS44492.1 - 0.0027 18.0 3.8 0.0091 16.4 3.8 1.9 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) ATG16 PF08614.11 EJS44492.1 - 0.0041 17.4 3.1 0.0041 17.4 3.1 1.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 EJS44492.1 - 0.0072 16.1 3.9 0.0072 16.1 3.9 1.9 2 0 0 2 2 2 1 Phage minor structural protein GP20 DUF4618 PF15397.6 EJS44492.1 - 0.0078 15.7 3.3 0.0078 15.7 3.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) TolA_bind_tri PF16331.5 EJS44492.1 - 0.0094 16.0 3.3 0.013 15.5 1.7 2.0 2 0 0 2 2 2 1 TolA binding protein trimerisation Prefoldin_2 PF01920.20 EJS44492.1 - 0.011 15.6 3.5 0.011 15.6 3.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.19 EJS44492.1 - 0.013 13.5 0.5 0.013 13.4 0.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.6 EJS44492.1 - 0.016 15.2 6.2 0.016 15.2 6.2 1.9 2 0 0 2 2 2 0 FlxA-like protein LPP PF04728.13 EJS44492.1 - 0.023 15.1 4.1 0.078 13.4 3.6 2.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Fib_alpha PF08702.10 EJS44492.1 - 0.035 14.3 6.1 0.035 14.3 6.1 1.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 EJS44492.1 - 0.042 13.1 3.0 0.069 12.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ABC_tran_CTD PF16326.5 EJS44492.1 - 0.047 13.9 0.7 0.047 13.9 0.7 2.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain Seryl_tRNA_N PF02403.22 EJS44492.1 - 0.051 13.8 7.8 0.17 12.2 3.2 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.12 EJS44492.1 - 0.061 13.9 1.9 0.13 12.9 1.9 1.6 1 0 0 1 1 1 0 SlyX Cauli_AT PF03233.13 EJS44492.1 - 0.067 13.1 5.8 0.037 13.9 2.7 1.9 2 0 0 2 2 2 0 Aphid transmission protein DUF16 PF01519.16 EJS44492.1 - 0.085 13.4 6.0 0.041 14.4 3.6 1.7 2 0 0 2 2 1 0 Protein of unknown function DUF16 GIT_CC PF16559.5 EJS44492.1 - 0.099 12.5 7.4 0.19 11.6 5.1 2.4 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor BLOC1_2 PF10046.9 EJS44492.1 - 0.1 12.9 7.2 0.061 13.6 3.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.11 EJS44492.1 - 0.16 12.5 4.7 0.065 13.8 1.7 1.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Spc24 PF08286.11 EJS44492.1 - 0.17 12.2 6.3 0.04 14.1 2.9 1.7 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 BRE1 PF08647.11 EJS44492.1 - 0.18 11.9 12.4 0.027 14.5 7.4 2.1 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 EJS44492.1 - 0.19 11.5 8.8 0.055 13.2 4.4 2.3 2 1 1 3 3 3 0 Septum formation initiator NPV_P10 PF05531.12 EJS44492.1 - 0.19 12.2 6.1 3.3 8.2 5.7 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 EJS44492.1 - 0.82 9.5 7.5 0.12 12.2 3.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Phage_GPO PF05929.11 EJS44492.1 - 0.99 9.0 5.7 0.28 10.8 2.7 1.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Cluap1 PF10234.9 EJS44492.1 - 1.3 8.3 10.0 0.039 13.4 2.1 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 Swi5 PF07061.11 EJS44492.1 - 2.2 8.4 7.4 0.4 10.8 3.2 1.9 2 0 0 2 2 2 0 Swi5 Bap31_Bap29_C PF18035.1 EJS44492.1 - 9.7 6.3 10.8 0.13 12.3 1.9 2.5 3 0 0 3 3 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain zf-LYAR PF08790.11 EJS44493.1 - 1.2e-14 53.9 7.7 2.5e-14 52.9 7.7 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 EJS44493.1 - 0.031 14.6 3.2 0.4 11.0 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 EJS44493.1 - 0.048 13.7 3.1 2 8.5 0.1 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zf_UBZ PF18439.1 EJS44493.1 - 0.054 13.1 1.2 7.9 6.2 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 EJS44493.1 - 0.35 11.8 6.2 1.8 9.6 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 EJS44493.1 - 0.46 11.0 5.0 4.7 7.7 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF4674 PF15719.5 EJS44493.1 - 1 9.3 11.4 0.066 13.3 4.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) zf-C2H2 PF00096.26 EJS44493.1 - 2.1 8.9 5.9 1.2 9.7 1.1 2.5 2 1 0 2 2 2 0 Zinc finger, C2H2 type Cofilin_ADF PF00241.20 EJS44494.1 - 4.4e-22 78.1 0.0 1.3e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 EJS44494.1 - 4.9e-14 51.7 0.9 1.1e-13 50.5 0.9 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EJS44494.1 - 5.8e-13 48.5 0.4 1.6e-12 47.1 0.4 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EJS44494.1 - 1.5e-06 27.8 0.0 3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Flocculin_t3 PF13928.6 EJS44495.1 - 2e-22 79.4 97.4 2.6e-07 31.0 17.1 22.3 18 5 0 18 18 18 5 Flocculin type 3 repeat Peptidase_S8 PF00082.22 EJS44497.1 - 4.3e-27 95.2 0.3 1.5e-26 93.3 0.3 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EJS44497.1 - 0.0035 18.0 0.0 0.0086 16.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ribosomal_L19 PF01245.20 EJS44498.1 - 2.1e-09 37.3 0.1 3.2e-09 36.7 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein L19 DUF3221 PF11518.8 EJS44498.1 - 0.011 16.1 0.1 0.041 14.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) WBS_methylT PF12589.8 EJS44499.1 - 3.2e-13 50.2 5.4 7.4e-13 49.1 5.4 1.6 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EJS44499.1 - 7.1e-12 45.8 0.0 1.2e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS44499.1 - 9e-11 42.3 0.0 2.1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJS44499.1 - 1.8e-06 28.6 0.0 1e-05 26.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EJS44499.1 - 3.1e-05 23.4 0.2 0.0006 19.2 0.0 2.6 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EJS44499.1 - 6.6e-05 22.8 0.0 0.0014 18.4 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EJS44499.1 - 0.00067 19.5 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJS44499.1 - 0.003 17.4 0.0 0.0056 16.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EJS44499.1 - 0.0088 15.5 0.1 0.047 13.1 0.0 2.0 2 1 1 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EJS44499.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.13 EJS44499.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MBOAT PF03062.19 EJS44500.1 - 2e-91 306.9 41.6 2.5e-91 306.6 41.6 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EJS44500.1 - 0.0029 17.8 4.5 0.0082 16.4 4.5 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MMU163 PF17119.5 EJS44500.1 - 0.013 14.7 0.6 0.021 14.0 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Corona_nucleoca PF00937.18 EJS44500.1 - 0.024 13.7 7.8 0.049 12.7 7.8 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RSRP PF17069.5 EJS44500.1 - 0.13 11.8 21.0 0.27 10.8 21.0 1.4 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Transformer PF06495.11 EJS44500.1 - 0.44 10.6 10.1 0.85 9.7 10.1 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein Secretin_N_2 PF07655.13 EJS44500.1 - 1.6 9.3 12.4 3.3 8.3 12.4 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain RAP1 PF07218.11 EJS44500.1 - 6.1 5.0 15.4 9.3 4.4 15.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 EJS44500.1 - 8.3 5.1 10.3 13 4.5 10.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ank_5 PF13857.6 EJS44501.1 - 4.9e-14 52.2 0.2 3.1e-10 40.1 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EJS44501.1 - 8.3e-09 35.8 0.4 9.8e-05 22.8 0.2 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EJS44501.1 - 9.9e-08 32.5 0.1 2.2e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EJS44501.1 - 1.3e-06 28.2 0.1 0.00056 20.2 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EJS44501.1 - 2.7e-05 24.4 0.6 0.024 15.1 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat SWIB PF02201.18 EJS44502.1 - 1.1e-05 25.2 0.0 0.00034 20.4 0.0 2.7 3 0 0 3 3 3 1 SWIB/MDM2 domain Thr_synth_N PF14821.6 EJS44503.1 - 9.4e-29 99.4 0.0 3.6e-28 97.6 0.0 2.1 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EJS44503.1 - 7.8e-11 41.9 0.0 1.6e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Helicase_IV_N PF12462.8 EJS44503.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Atx10homo_assoc PF09759.9 EJS44504.1 - 4.5e-35 119.6 2.3 4.7e-35 119.6 0.3 2.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EJS44504.1 - 0.029 13.8 0.1 0.12 11.8 0.1 2.0 2 0 0 2 2 2 0 Armadillo-like WD40 PF00400.32 EJS44505.1 - 2.8e-46 154.5 15.4 4.1e-09 36.9 0.2 12.5 13 0 0 13 13 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44505.1 - 1.7e-32 111.6 0.0 0.00048 20.4 0.0 9.2 4 2 5 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EJS44505.1 - 1.6e-22 79.9 0.0 2.8e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.11 EJS44505.1 - 8.2e-10 38.9 6.4 0.0013 18.7 0.0 6.6 4 3 1 6 6 6 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EJS44505.1 - 1.1e-07 31.5 1.7 0.33 10.2 0.0 5.0 5 1 2 7 7 7 2 WD40-like domain Ge1_WD40 PF16529.5 EJS44505.1 - 3.5e-07 29.5 6.0 0.14 11.1 0.0 6.7 4 3 3 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EJS44505.1 - 8.8e-06 25.3 0.7 0.24 10.7 0.1 4.2 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EJS44505.1 - 0.00022 20.0 3.6 0.19 10.4 0.0 4.8 3 2 1 5 5 5 1 Nucleoporin Nup120/160 WD40_3 PF15911.5 EJS44505.1 - 0.0011 18.9 0.0 0.0058 16.6 0.0 2.3 1 0 0 1 1 1 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EJS44505.1 - 0.0018 16.8 0.3 0.54 8.7 0.0 3.5 3 1 0 4 4 4 1 Cytochrome D1 heme domain PQQ_2 PF13360.6 EJS44505.1 - 0.0022 17.6 0.2 0.16 11.5 0.1 3.0 1 1 1 2 2 2 1 PQQ-like domain PD40 PF07676.12 EJS44505.1 - 0.011 15.7 0.5 47 4.1 0.0 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 EJS44505.1 - 1.3 8.8 3.8 4.9 6.9 0.0 3.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature UPF0029 PF01205.19 EJS44506.1 - 1.5e-31 108.8 0.1 2.8e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EJS44506.1 - 2.8e-09 37.3 0.1 7.5e-09 35.9 0.1 1.7 1 1 0 1 1 1 1 RWD domain TPR_1 PF00515.28 EJS44507.1 - 6.2e-11 41.6 0.5 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EJS44507.1 - 5e-10 38.7 0.9 0.00051 19.9 0.4 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJS44507.1 - 5.3e-08 33.1 0.5 0.0021 18.7 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EJS44507.1 - 9.1e-08 32.5 1.5 1.3e-07 32.0 1.5 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EJS44507.1 - 2.8e-07 30.2 0.3 0.0036 17.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EJS44507.1 - 3e-07 31.0 1.3 7.6e-07 29.7 0.5 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJS44507.1 - 1.1e-05 25.2 0.2 0.093 12.8 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EJS44507.1 - 1.2e-05 24.9 1.8 0.00014 21.5 0.2 2.3 1 1 1 2 2 2 1 TPR repeat Fis1_TPR_C PF14853.6 EJS44507.1 - 0.00027 20.9 0.2 0.051 13.6 0.1 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 EJS44507.1 - 0.001 19.3 0.8 0.0043 17.3 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EJS44507.1 - 0.0012 19.3 5.9 0.1 13.3 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EJS44507.1 - 0.0017 18.8 0.0 0.87 10.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EJS44507.1 - 0.0023 17.7 2.9 0.37 10.7 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EJS44507.1 - 0.0024 18.0 0.3 0.0041 17.2 0.2 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EJS44507.1 - 0.016 15.5 2.0 0.28 11.5 1.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EJS44507.1 - 0.02 15.1 1.4 0.06 13.6 1.1 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EJS44507.1 - 0.025 14.0 2.4 0.12 11.7 2.4 1.8 1 1 0 1 1 1 0 MalT-like TPR region SRP_TPR_like PF17004.5 EJS44507.1 - 0.054 13.5 0.0 0.072 13.1 0.0 1.3 1 1 0 1 1 1 0 Putative TPR-like repeat Ytp1 PF10355.9 EJS44508.1 - 1.7e-111 371.9 13.6 2.4e-111 371.4 13.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EJS44508.1 - 2.2e-29 101.4 4.5 2.2e-29 101.4 4.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Myb_DNA-binding PF00249.31 EJS44509.1 - 1.5e-16 60.3 0.0 5.2e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJS44509.1 - 5e-06 26.7 0.6 0.014 15.7 0.1 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EJS44509.1 - 0.0067 16.3 0.1 0.0067 16.3 0.1 2.6 3 0 0 3 3 3 1 Myb DNA-binding like ELO PF01151.18 EJS44510.1 - 5.4e-60 203.0 24.3 6.5e-60 202.8 24.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SPX PF03105.19 EJS44511.1 - 2.1e-51 176.1 14.3 2.8e-51 175.6 14.3 1.1 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.16 EJS44511.1 - 6.3e-23 81.4 39.4 6.2e-17 61.8 16.2 2.2 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 EJS44511.1 - 2.4e-20 73.0 29.8 3.7e-20 72.4 29.8 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region RFX_DNA_binding PF02257.15 EJS44511.1 - 0.012 16.2 1.1 2.2 9.0 0.1 2.3 2 0 0 2 2 2 0 RFX DNA-binding domain PfkB PF00294.24 EJS44512.1 - 1.6e-10 40.8 0.0 2.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 EJS44512.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase TENA_THI-4 PF03070.16 EJS44513.1 - 1.3e-12 48.0 1.1 1.8e-12 47.5 1.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family LSM PF01423.22 EJS44514.1 - 2e-12 46.6 0.0 2.2e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain GcpE PF04551.14 EJS44514.1 - 0.021 13.9 0.0 0.025 13.7 0.0 1.0 1 0 0 1 1 1 0 GcpE protein SM-ATX PF14438.6 EJS44514.1 - 0.058 13.5 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Bac_rhodopsin PF01036.18 EJS44515.1 - 4.4e-55 186.7 17.3 5.5e-55 186.4 17.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 EJS44515.1 - 0.053 13.2 9.8 0.18 11.5 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) tRNA-synt_2 PF00152.20 EJS44516.1 - 9.9e-79 264.7 0.0 1.4e-78 264.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EJS44516.1 - 1.3e-08 34.7 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PMP1_2 PF08114.11 EJS44517.1 - 2.4e-29 100.8 3.7 2.6e-29 100.7 3.7 1.0 1 0 0 1 1 1 1 ATPase proteolipid family FeoB_associated PF12669.7 EJS44517.1 - 0.097 13.1 1.4 0.12 12.8 1.4 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Cytochrom_B558a PF05038.13 EJS44517.1 - 0.1 12.2 0.2 0.1 12.2 0.2 1.1 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit CD34_antigen PF06365.12 EJS44517.1 - 0.11 12.1 0.3 0.11 12.1 0.3 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family Phosphodiest PF01663.22 EJS44518.1 - 3.4e-90 303.2 3.2 4.7e-90 302.8 3.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EJS44518.1 - 0.0023 17.4 0.1 0.01 15.2 0.1 2.0 1 1 0 1 1 1 1 Sulfatase LpqV PF17301.2 EJS44518.1 - 0.022 15.0 0.3 0.047 13.9 0.3 1.5 1 0 0 1 1 1 0 Putative lipoprotein LpqV BUD22 PF09073.10 EJS44518.1 - 0.069 12.5 1.8 0.11 11.9 1.8 1.2 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 EJS44518.1 - 0.27 10.5 5.4 0.49 9.7 5.4 1.3 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 EJS44518.1 - 1.3 7.0 3.7 2 6.4 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ras PF00071.22 EJS44519.1 - 2.2e-45 154.2 0.0 2.5e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS44519.1 - 6.1e-15 55.5 0.0 9.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS44519.1 - 4.2e-07 29.6 0.0 5.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EJS44519.1 - 3.7e-05 23.8 0.0 5.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJS44519.1 - 0.0005 19.7 0.1 0.095 12.2 0.0 2.2 1 1 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EJS44519.1 - 0.002 17.6 0.0 0.0024 17.3 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EJS44519.1 - 0.0036 17.4 0.0 0.0094 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 EJS44519.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 EJS44519.1 - 0.04 14.2 0.0 5.3 7.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EJS44519.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain GATA PF00320.27 EJS44520.1 - 3e-11 42.7 4.0 6.7e-11 41.6 4.0 1.6 1 0 0 1 1 1 1 GATA zinc finger ZZ PF00569.17 EJS44520.1 - 0.042 13.7 0.2 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, ZZ type Pkinase PF00069.25 EJS44521.1 - 8.3e-49 166.3 0.0 1.4e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44521.1 - 1.7e-27 96.3 0.0 2.6e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS44521.1 - 0.003 16.9 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJS44521.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EJS44521.1 - 0.022 14.1 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EJS44521.1 - 0.07 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EJS44521.1 - 0.15 11.7 0.3 0.86 9.2 0.0 2.3 3 0 0 3 3 3 0 RIO1 family BAR PF03114.18 EJS44522.1 - 6.1e-57 193.0 1.4 7.2e-57 192.8 1.4 1.0 1 0 0 1 1 1 1 BAR domain DUF1496 PF07383.12 EJS44522.1 - 0.0078 15.8 0.6 0.015 14.9 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1496) BAR_3 PF16746.5 EJS44522.1 - 0.013 15.2 0.6 0.026 14.2 0.6 1.5 1 1 0 1 1 1 0 BAR domain of APPL family HAUS-augmin3 PF14932.6 EJS44522.1 - 0.024 14.2 1.5 0.08 12.5 0.3 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4164 PF13747.6 EJS44522.1 - 0.1 12.9 4.0 0.076 13.3 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Seryl_tRNA_N PF02403.22 EJS44522.1 - 0.1 12.8 3.8 3.7 7.8 0.9 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 EJS44522.1 - 0.11 12.8 5.4 0.083 13.1 2.3 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2313 PF10076.9 EJS44522.1 - 0.11 12.3 0.1 0.35 10.7 0.0 1.8 1 1 1 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) BRE1 PF08647.11 EJS44522.1 - 3.3 7.9 7.4 25 5.0 3.5 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Gpr1_Fun34_YaaH PF01184.19 EJS44523.1 - 7.7e-96 319.6 19.1 9e-96 319.4 19.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ABC2_membrane PF01061.24 EJS44524.1 - 9.2e-39 133.0 19.7 9.2e-39 133.0 19.7 2.2 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 EJS44524.1 - 7.7e-29 100.9 0.1 2e-28 99.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EJS44524.1 - 0.00037 20.4 0.2 0.00084 19.3 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EJS44524.1 - 0.0013 18.6 0.7 0.57 9.9 0.3 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system EGF_2 PF07974.13 EJS44524.1 - 0.012 16.0 25.1 0.023 15.1 6.2 3.7 3 0 0 3 3 3 0 EGF-like domain AAA_29 PF13555.6 EJS44524.1 - 0.018 14.8 0.3 0.04 13.7 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EJS44524.1 - 0.032 14.2 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 EJS44524.1 - 0.089 13.1 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EJS44524.1 - 0.091 13.3 3.4 0.45 11.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EJS44524.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.24 EJS44524.1 - 0.12 12.5 30.6 0.05 13.8 2.1 4.1 4 0 0 4 4 4 0 Laminin EGF domain AAA_28 PF13521.6 EJS44524.1 - 0.14 12.4 0.4 0.24 11.6 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EJS44524.1 - 0.17 12.2 0.2 0.54 10.6 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain PGK PF00162.19 EJS44525.1 - 1.8e-150 501.1 0.3 2e-150 501.0 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Peptidase_S51 PF03575.17 EJS44525.1 - 0.16 11.6 0.3 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S51 Mgr1 PF08602.10 EJS44526.1 - 7.1e-156 518.9 0.9 5e-113 377.8 1.0 2.0 1 1 1 2 2 2 2 Mgr1-like, i-AAA protease complex subunit Thioredoxin PF00085.20 EJS44527.1 - 1.7e-61 204.6 0.8 5.1e-31 106.7 0.4 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EJS44527.1 - 5.9e-23 81.7 4.0 1.2e-16 61.2 1.4 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EJS44527.1 - 1e-07 32.0 0.0 0.0038 17.4 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EJS44527.1 - 3.9e-07 29.7 0.4 0.0018 17.7 0.8 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EJS44527.1 - 6e-07 29.4 0.1 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_2 PF13098.6 EJS44527.1 - 1.2e-06 29.0 0.7 0.013 15.9 0.1 3.2 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EJS44527.1 - 9.2e-06 25.9 0.4 0.098 13.0 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EJS44527.1 - 0.00013 21.7 0.1 0.078 12.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.10 EJS44527.1 - 0.002 17.8 0.1 0.68 9.6 0.0 2.5 2 0 0 2 2 2 2 Redoxin TraF PF13728.6 EJS44527.1 - 0.038 13.8 0.0 0.29 10.9 0.0 2.4 3 0 0 3 3 3 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 EJS44527.1 - 1.3 9.3 3.0 20 5.5 0.0 2.9 2 1 0 2 2 2 0 Glutaredoxin Hexokinase_2 PF03727.16 EJS44528.1 - 6.3e-76 255.0 0.0 8.5e-76 254.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EJS44528.1 - 7.9e-71 238.1 0.0 1.3e-70 237.3 0.0 1.4 1 0 0 1 1 1 1 Hexokinase WD40 PF00400.32 EJS44529.1 - 8.5e-14 51.7 3.4 0.0075 17.1 0.1 6.3 4 1 1 5 5 5 4 WD domain, G-beta repeat DUF4221 PF13970.6 EJS44529.1 - 0.00021 21.0 0.4 0.0011 18.6 0.1 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4221) ANAPC4_WD40 PF12894.7 EJS44529.1 - 0.014 15.7 0.0 2.5 8.4 0.0 3.5 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EJS44529.1 - 0.054 12.7 0.0 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller ATG22 PF11700.8 EJS44530.1 - 4e-153 510.5 27.7 4.7e-153 510.3 27.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EJS44530.1 - 6.7e-06 25.3 40.7 3e-05 23.1 6.6 3.6 1 1 2 3 3 3 2 Major Facilitator Superfamily La PF05383.17 EJS44531.1 - 1e-16 60.7 0.1 2.6e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 La domain Hid1 PF12722.7 EJS44531.1 - 0.17 10.0 12.2 0.29 9.2 12.2 1.6 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glutaredoxin PF00462.24 EJS44532.1 - 8.8e-15 54.7 0.0 1.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 EJS44532.1 - 0.012 15.6 0.1 0.021 14.9 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 EJS44532.1 - 0.042 14.0 0.2 0.11 12.7 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin DSBA PF01323.20 EJS44532.1 - 0.13 12.0 0.5 5.3 6.8 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain GAT PF03127.14 EJS44533.1 - 0.00066 19.9 0.0 0.0017 18.6 0.0 1.8 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 EJS44533.1 - 0.0022 17.8 0.1 0.004 17.0 0.1 1.4 1 0 0 1 1 1 1 VHS domain DUF4218 PF13960.6 EJS44533.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) SelR PF01641.18 EJS44534.1 - 9.3e-46 154.8 0.1 1.2e-45 154.5 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EJS44534.1 - 0.007 16.6 0.5 0.013 15.7 0.5 1.5 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 EJS44534.1 - 0.054 13.5 1.5 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon SAM_Ste50p PF09235.10 EJS44535.1 - 1.6e-36 124.4 4.4 3.5e-36 123.3 4.4 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif RA PF00788.23 EJS44535.1 - 2.2e-15 57.0 0.0 5.6e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RRM_Rrp7 PF17799.1 EJS44536.1 - 3.8e-39 134.1 0.4 8.7e-39 132.9 0.4 1.6 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 EJS44536.1 - 5.7e-26 91.0 7.3 1e-25 90.2 7.3 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Glyoxalase_2 PF12681.7 EJS44536.1 - 0.021 14.7 0.2 0.11 12.5 0.0 2.2 1 1 0 2 2 2 0 Glyoxalase-like domain Histidinol_dh PF00815.20 EJS44537.1 - 6.9e-160 532.5 0.5 6.9e-160 532.5 0.5 1.6 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.18 EJS44537.1 - 1.4e-27 95.3 0.1 2.8e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EJS44537.1 - 1.5e-14 54.1 0.2 6.9e-14 52.0 0.2 2.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase CST-I PF06002.12 EJS44537.1 - 0.042 13.6 0.0 0.68 9.6 0.0 2.4 1 1 1 2 2 2 0 Alpha-2,3-sialyltransferase (CST-I) CAP_GLY PF01302.25 EJS44538.1 - 7.6e-14 51.5 0.1 1.6e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain Lebercilin PF15619.6 EJS44538.1 - 0.0003 20.5 32.5 0.00069 19.3 18.6 2.3 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease ACT_5 PF13710.6 EJS44538.1 - 0.2 11.5 1.0 10 6.1 0.0 3.1 3 0 0 3 3 3 0 ACT domain zf-CCHC PF00098.23 EJS44538.1 - 0.2 11.8 3.9 0.39 10.9 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Tmemb_cc2 PF10267.9 EJS44538.1 - 0.5 9.5 30.4 0.34 10.0 0.6 3.3 1 1 2 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein TMPIT PF07851.13 EJS44538.1 - 1.2 8.3 18.4 0.24 10.6 3.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein CLIP1_ZNF PF16641.5 EJS44538.1 - 1.5 8.8 4.3 4.7 7.2 4.3 1.8 1 0 0 1 1 1 0 CLIP1 zinc knuckle Bap31_Bap29_C PF18035.1 EJS44538.1 - 2.1 8.4 21.2 0.46 10.5 5.8 4.3 3 1 1 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain OmpH PF03938.14 EJS44538.1 - 8.5 6.7 29.1 12 6.2 3.7 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TPR_2 PF07719.17 EJS44539.1 - 0.024 14.7 0.0 0.07 13.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2973 PF11189.8 EJS44539.1 - 7.7 6.7 5.6 29 4.9 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2973) SH3_1 PF00018.28 EJS44540.1 - 5e-06 26.0 0.1 3.7e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EJS44540.1 - 5.5e-05 23.0 0.0 0.00015 21.5 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EJS44540.1 - 0.0043 16.7 0.0 0.0087 15.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Mucin PF01456.17 EJS44540.1 - 0.033 14.2 11.2 0.059 13.4 11.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Nitroreductase PF00881.24 EJS44541.1 - 3.4e-07 30.5 0.0 5.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family DUF1103 PF06513.11 EJS44541.1 - 0.17 11.5 0.1 0.22 11.1 0.1 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Pkinase PF00069.25 EJS44542.1 - 1.6e-70 237.5 0.0 2.9e-70 236.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44542.1 - 6e-35 120.8 0.0 1.1e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 EJS44542.1 - 3.5e-28 97.7 3.4 7e-28 96.7 0.2 2.9 3 0 0 3 3 3 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 EJS44542.1 - 1.2e-05 24.8 0.0 2.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EJS44542.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EJS44542.1 - 0.11 11.9 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Iso_dh PF00180.20 EJS44544.1 - 4.7e-126 420.6 0.0 5.3e-126 420.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_ligase_aden PF01653.18 EJS44544.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Aminotran_5 PF00266.19 EJS44545.1 - 5.7e-103 344.7 0.0 7e-103 344.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EJS44545.1 - 1.5e-08 34.2 0.0 3.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EJS44545.1 - 3.9e-08 32.9 0.0 5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EJS44545.1 - 1e-06 28.3 0.1 2.4e-06 27.1 0.1 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EJS44545.1 - 0.00025 19.9 0.0 0.0004 19.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 EJS44545.1 - 0.0021 16.7 0.2 0.003 16.2 0.2 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Dcc1 PF09724.9 EJS44546.1 - 2.7e-79 266.9 0.1 3.1e-79 266.7 0.1 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Hexose_dehydrat PF03559.14 EJS44546.1 - 0.044 13.2 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase DUF3507 PF12015.8 EJS44547.1 - 4.8e-74 248.0 0.0 9.7e-74 247.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) RhoGEF PF00621.20 EJS44547.1 - 0.0068 16.7 0.6 0.0068 16.7 0.6 2.9 2 1 1 3 3 3 1 RhoGEF domain RRM_1 PF00076.22 EJS44548.1 - 9.9e-60 198.3 0.1 2.5e-19 68.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EJS44548.1 - 0.0026 17.4 0.0 0.42 10.2 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EJS44548.1 - 0.0027 17.5 0.3 1.2 8.9 0.0 2.7 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EJS44548.1 - 0.18 11.7 0.0 2.9 7.8 0.0 2.7 3 1 0 3 3 3 0 Occluded RNA-recognition motif DUF1325 PF07039.11 EJS44549.1 - 1.4e-35 122.3 0.0 3.1e-35 121.1 0.0 1.6 2 0 0 2 2 2 1 SGF29 tudor-like domain Tudor_3 PF18115.1 EJS44549.1 - 4.1e-06 26.5 0.0 9.3e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 EJS44549.1 - 0.0042 17.5 0.1 0.89 10.1 0.1 2.4 2 0 0 2 2 2 2 Agenet domain DUF4537 PF15057.6 EJS44549.1 - 0.026 14.6 0.0 0.091 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) DUF2856 PF11043.8 EJS44549.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) ALS_ss_C PF10369.9 EJS44550.1 - 6.3e-15 55.2 0.0 3.5e-14 52.7 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EJS44550.1 - 1.5e-13 50.3 0.1 2.6e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EJS44550.1 - 5.3e-08 32.6 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain Limkain-b1 PF11608.8 EJS44550.1 - 0.00066 19.7 0.2 0.0049 16.9 0.0 2.4 3 0 0 3 3 3 1 Limkain b1 UEV PF05743.13 EJS44551.1 - 2.4e-26 91.9 0.1 5.2e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EJS44551.1 - 2.7e-23 81.7 0.4 6.3e-23 80.5 0.1 1.8 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 EJS44551.1 - 0.00023 20.8 1.2 0.00051 19.7 1.2 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rer1 PF03248.13 EJS44553.1 - 8e-75 250.3 4.3 9.3e-75 250.1 4.3 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 EJS44553.1 - 0.27 10.8 5.7 0.049 13.2 2.1 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Septin PF00735.18 EJS44554.1 - 9.1e-107 356.5 1.0 1.1e-106 356.3 1.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EJS44554.1 - 6.8e-10 39.0 0.1 1.3e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EJS44554.1 - 1e-07 32.0 0.3 5.1e-07 29.7 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EJS44554.1 - 2.3e-07 30.6 0.2 2.8e-05 23.7 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EJS44554.1 - 8.8e-07 28.5 0.2 2.7e-06 26.9 0.2 1.8 1 1 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EJS44554.1 - 0.00032 20.8 1.0 0.2 11.7 0.2 2.6 1 1 0 2 2 2 2 Dynamin family NB-ARC PF00931.22 EJS44554.1 - 0.00033 19.9 0.1 0.00051 19.3 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EJS44554.1 - 0.0014 19.0 0.1 0.0027 18.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EJS44554.1 - 0.0017 17.8 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 EJS44554.1 - 0.002 18.4 0.1 0.0052 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 EJS44554.1 - 0.0021 17.4 0.3 0.016 14.6 0.3 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 EJS44554.1 - 0.0062 17.1 1.1 0.017 15.6 0.6 2.0 2 1 0 2 2 2 1 ABC transporter AAA_14 PF13173.6 EJS44554.1 - 0.0088 16.1 0.1 0.053 13.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain IIGP PF05049.13 EJS44554.1 - 0.0091 15.1 0.2 0.018 14.1 0.2 1.6 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 EJS44554.1 - 0.01 15.3 0.1 1 8.9 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 EJS44554.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EJS44554.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EJS44554.1 - 0.02 14.6 0.8 0.051 13.3 0.3 1.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EJS44554.1 - 0.041 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EJS44554.1 - 0.045 13.5 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Reprolysin_3 PF13582.6 EJS44554.1 - 0.094 13.2 0.1 0.23 12.0 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Ribosomal_L32p PF01783.23 EJS44555.1 - 5.4e-12 45.8 5.5 8.4e-12 45.2 5.5 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 EJS44555.1 - 0.042 13.3 1.9 0.077 12.4 1.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain RecR PF02132.15 EJS44555.1 - 0.22 11.1 0.8 0.37 10.4 0.8 1.4 1 0 0 1 1 1 0 RecR protein FMN_red PF03358.15 EJS44556.1 - 6.3e-08 32.5 0.4 9.1e-08 32.0 0.0 1.4 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 EJS44556.1 - 5e-05 23.5 0.0 9.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 EJS44556.1 - 9.3e-05 22.2 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold Citrate_synt PF00285.21 EJS44557.1 - 2.9e-103 345.7 0.0 3.6e-103 345.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain MATalpha_HMGbox PF04769.12 EJS44558.1 - 3.1e-15 56.0 0.2 4.2e-15 55.6 0.2 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box PALP PF00291.25 EJS44559.1 - 1.6e-60 205.1 0.0 1.8e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Asparaginase_C PF17763.1 EJS44559.1 - 0.025 14.8 0.1 1.9 8.8 0.0 2.7 3 0 0 3 3 3 0 Glutaminase/Asparaginase C-terminal domain DAGK_cat PF00781.24 EJS44559.1 - 0.089 12.4 0.1 0.69 9.5 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Vac17 PF17321.2 EJS44560.1 - 3.9e-140 468.2 26.4 4.8e-140 467.9 26.4 1.1 1 0 0 1 1 1 1 Vacuole-related protein 17 Enkurin PF13864.6 EJS44560.1 - 0.43 11.0 7.3 0.26 11.7 2.0 2.8 2 1 1 3 3 3 0 Calmodulin-binding KH_8 PF17903.1 EJS44561.1 - 4.7e-31 106.7 1.9 6.3e-31 106.3 0.0 2.1 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 EJS44561.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 KH domain Spore_GerAC PF05504.11 EJS44561.1 - 0.15 12.2 2.6 5.2 7.3 1.6 2.4 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal LMBR1 PF04791.16 EJS44562.1 - 1.4 7.8 3.5 1.4 7.7 3.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_M3 PF01432.20 EJS44563.1 - 2.3e-157 525.0 0.2 3.1e-157 524.5 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M3 MT-A70 PF05063.14 EJS44565.1 - 2.2e-13 50.5 0.1 3.2e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 MT-A70 PIG-X PF08320.12 EJS44566.1 - 1e-28 100.7 0.0 1.4e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 ATP_transf PF09830.9 EJS44568.1 - 3.3e-19 68.8 0.0 6.4e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 EJS44568.1 - 3e-05 23.5 0.0 7.7e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4931) DUF4922 PF16269.5 EJS44568.1 - 0.00025 20.9 0.3 0.0059 16.4 0.3 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) HIT PF01230.23 EJS44568.1 - 0.0034 18.1 0.0 0.007 17.1 0.0 1.5 1 0 0 1 1 1 1 HIT domain Recep_L_domain PF01030.24 EJS44570.1 - 1.1e-08 35.2 14.6 0.00056 20.0 0.7 4.8 1 1 2 4 4 4 4 Receptor L domain LRR_5 PF13306.6 EJS44570.1 - 0.016 15.2 0.6 0.016 15.2 0.6 2.8 1 1 2 3 3 3 0 BspA type Leucine rich repeat region (6 copies) PGG PF13962.6 EJS44570.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function LRR_9 PF14580.6 EJS44570.1 - 2 7.9 6.6 1.2 8.6 2.6 2.5 1 1 1 2 2 2 0 Leucine-rich repeat CTP_transf_like PF01467.26 EJS44571.1 - 1.6e-06 28.4 0.0 4.3e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 EJS44571.1 - 0.078 12.4 0.1 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 ATP-sulfurylase EMC1_C PF07774.13 EJS44572.1 - 2.2e-64 217.0 0.1 3.6e-64 216.4 0.1 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal Rrn6 PF10214.9 EJS44573.1 - 2e-159 532.9 28.6 2.6e-159 532.4 28.6 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF5102 PF17104.5 EJS44574.1 - 3e-08 34.1 9.9 0.00036 20.7 2.8 3.3 2 1 0 2 2 2 2 Domain of unknown function (DUF5102) Haspin_kinase PF12330.8 EJS44575.1 - 4.9e-138 460.1 14.7 4.9e-138 460.1 14.7 1.8 2 1 0 2 2 2 1 Haspin like kinase domain WD40 PF00400.32 EJS44576.1 - 1.1e-31 108.3 13.2 1.6e-08 35.0 0.1 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44576.1 - 9e-15 54.8 0.0 0.0052 17.1 0.0 5.9 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EJS44576.1 - 1.6e-08 34.2 0.3 0.31 11.0 0.0 5.1 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat HIRA_B PF09453.10 EJS44576.1 - 1.2e-07 31.3 0.5 3.6e-07 29.9 0.5 1.9 1 0 0 1 1 1 1 HIRA B motif Hira PF07569.11 EJS44576.1 - 2.3e-06 27.5 0.0 1.1e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 TUP1-like enhancer of split Ge1_WD40 PF16529.5 EJS44576.1 - 7.3e-06 25.2 0.0 1.8 7.4 0.0 3.8 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EJS44576.1 - 0.0059 16.0 0.0 0.15 11.4 0.0 2.7 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EJS44576.1 - 0.056 12.8 0.0 0.56 9.5 0.0 2.6 4 0 0 4 4 4 0 WD40-like domain IKI3 PF04762.12 EJS44576.1 - 0.089 10.8 0.1 8.3 4.3 0.0 2.7 2 1 1 3 3 3 0 IKI3 family Histone_H2A_C PF16211.5 EJS44577.1 - 7e-21 73.7 1.5 1.2e-20 73.0 1.5 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EJS44577.1 - 1.6e-17 64.0 0.0 2.3e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EJS44577.1 - 7.8e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 EJS44577.1 - 0.055 13.4 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 LcrG protein Histone PF00125.24 EJS44578.1 - 1.5e-19 70.6 2.6 2e-19 70.3 2.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EJS44578.1 - 8e-06 26.1 0.1 1.6e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EJS44578.1 - 0.0016 18.9 0.0 0.0027 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 EJS44578.1 - 0.0063 16.7 0.0 0.0098 16.1 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein YscO-like PF16789.5 EJS44578.1 - 0.08 13.0 0.2 0.095 12.7 0.2 1.2 1 0 0 1 1 1 0 YscO-like protein Thiamine_BP PF01910.17 EJS44579.1 - 3.2e-29 100.7 0.1 3.6e-29 100.5 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Prenyltransf PF01255.19 EJS44580.1 - 8.1e-73 244.6 0.0 1e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase polyprenyl_synt PF00348.17 EJS44581.1 - 1.1e-67 227.8 0.0 1.8e-65 220.6 0.0 2.9 1 1 0 1 1 1 1 Polyprenyl synthetase DUF2990 PF11693.8 EJS44581.1 - 0.091 12.9 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) Mannosyl_trans2 PF04188.13 EJS44582.1 - 7.6e-152 506.7 41.3 1.4e-150 502.5 41.3 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) DUF2304 PF10066.9 EJS44582.1 - 0.032 14.5 0.5 0.032 14.5 0.5 4.0 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2304) Aldedh PF00171.22 EJS44583.1 - 1.9e-157 524.5 0.0 2.2e-157 524.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EJS44583.1 - 0.046 13.2 0.1 0.1 12.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) CENP-T_C PF15511.6 EJS44584.1 - 2.7e-09 37.1 0.1 3.2e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EJS44584.1 - 5.5e-05 23.2 0.1 7.8e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EJS44584.1 - 0.00014 22.3 0.1 0.00016 22.1 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EJS44584.1 - 0.00021 21.5 0.1 0.00036 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EJS44584.1 - 0.00029 21.2 0.1 0.00039 20.7 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EJS44584.1 - 0.0089 16.1 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EJS44584.1 - 0.04 13.9 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 EJS44584.1 - 0.073 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 EJS44585.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EJS44585.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EJS44585.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EJS44585.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EJS44585.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EJS44585.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Pyrophosphatase PF00719.19 EJS44586.1 - 1e-58 197.7 0.3 1.3e-58 197.3 0.3 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Glutaredoxin PF00462.24 EJS44587.1 - 2.9e-14 53.0 0.0 6.1e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin DUF3848 PF12959.7 EJS44587.1 - 0.022 14.8 1.4 0.043 13.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) Mannosyl_trans3 PF11051.8 EJS44588.1 - 1.2e-83 280.6 0.0 2.5e-83 279.6 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative DUF3724 PF12521.8 EJS44588.1 - 0.063 13.2 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) RB_B PF01857.20 EJS44588.1 - 0.14 12.2 0.3 0.34 10.9 0.3 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain CYSTM PF12734.7 EJS44589.1 - 5.5e-16 58.6 9.5 5.5e-16 58.6 9.5 5.2 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance HEAT PF02985.22 EJS44590.1 - 3.8e-22 76.5 4.4 0.0008 19.5 0.0 9.1 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 EJS44590.1 - 3.3e-20 72.2 1.0 6.1e-12 45.8 0.0 7.8 8 0 0 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.6 EJS44590.1 - 1e-12 48.3 0.0 0.0002 21.7 0.0 6.5 4 3 2 6 6 6 3 HEAT repeats Cnd1 PF12717.7 EJS44590.1 - 5.3e-09 36.3 5.1 0.0059 16.7 0.0 4.5 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EJS44590.1 - 2.1e-05 23.3 3.1 0.073 11.6 0.0 3.7 3 2 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EJS44590.1 - 9.6e-05 22.9 0.0 1.9 9.2 0.0 4.5 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 EJS44590.1 - 0.00022 21.1 1.6 0.014 15.3 0.2 3.5 3 1 0 3 3 3 1 Importin-beta N-terminal domain UNC45-central PF11701.8 EJS44590.1 - 0.3 11.0 1.6 0.5 10.3 0.2 2.1 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central GalP_UDP_tr_C PF02744.17 EJS44591.1 - 4.4e-67 225.0 0.6 7.9e-67 224.1 0.1 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 EJS44591.1 - 7.4e-67 225.3 0.1 1e-66 224.9 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4921 PF16268.5 EJS44591.1 - 0.027 13.3 0.1 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) WG_beta_rep PF14903.6 EJS44591.1 - 0.11 12.8 0.3 0.34 11.3 0.1 2.0 2 0 0 2 2 2 0 WG containing repeat DUF3288 PF11691.8 EJS44591.1 - 0.13 12.3 0.1 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) DUF3721 PF12518.8 EJS44591.1 - 0.43 10.5 1.6 0.9 9.4 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function Aldose_epim PF01263.20 EJS44592.1 - 3.2e-83 279.5 0.6 4.2e-83 279.1 0.6 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase GDP_Man_Dehyd PF16363.5 EJS44592.1 - 4.3e-57 194.0 0.0 6.4e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EJS44592.1 - 3.5e-53 180.5 0.0 8.6e-53 179.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EJS44592.1 - 1.1e-18 67.5 0.0 8e-17 61.3 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EJS44592.1 - 4.4e-15 55.4 0.0 2e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EJS44592.1 - 6.6e-10 38.5 0.0 1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EJS44592.1 - 7.6e-08 32.5 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EJS44592.1 - 5.8e-07 29.2 0.0 9.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EJS44592.1 - 7e-06 25.4 0.0 0.001 18.3 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EJS44592.1 - 8.7e-05 22.5 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding TadF PF16964.5 EJS44592.1 - 0.18 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative tight adherence pilin protein F GalKase_gal_bdg PF10509.9 EJS44593.1 - 3.2e-22 77.8 0.0 7.4e-22 76.7 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EJS44593.1 - 1.1e-16 60.8 0.7 3.7e-16 59.1 0.5 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EJS44593.1 - 2.1e-12 47.2 0.0 4.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Transp_cyt_pur PF02133.15 EJS44594.1 - 5.6e-182 605.4 36.6 6.6e-182 605.2 36.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Macro PF01661.21 EJS44595.1 - 7.9e-29 100.1 0.0 9.4e-29 99.9 0.0 1.1 1 0 0 1 1 1 1 Macro domain Macin PF14865.6 EJS44595.1 - 0.033 14.7 0.2 0.075 13.6 0.2 1.7 1 1 0 1 1 1 0 Macin Chitin_synth_2 PF03142.15 EJS44596.1 - 1.1e-287 954.9 0.2 1.1e-287 954.9 0.2 1.6 2 0 0 2 2 2 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 EJS44596.1 - 1.2e-11 45.0 0.0 5.8e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EJS44596.1 - 1.4e-09 38.2 5.5 5.9e-09 36.1 5.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EJS44596.1 - 0.0013 18.2 0.1 0.0057 16.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Reticulon PF02453.17 EJS44596.1 - 0.15 12.0 7.0 0.18 11.7 1.0 3.1 3 0 0 3 3 3 0 Reticulon DUF3139 PF11337.8 EJS44596.1 - 0.31 11.7 1.1 2 9.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) SCO1-SenC PF02630.14 EJS44597.1 - 3.3e-47 159.8 0.0 4.5e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EJS44597.1 - 7.3e-06 25.9 0.0 1.7e-05 24.7 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EJS44597.1 - 0.015 15.6 0.1 0.069 13.5 0.0 2.1 2 1 0 2 2 2 0 Thioredoxin-like YchF-GTPase_C PF06071.13 EJS44598.1 - 5.6e-36 122.6 0.1 1.8e-35 121.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EJS44598.1 - 9.1e-18 64.4 0.0 1e-16 61.0 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJS44598.1 - 0.0037 16.8 0.0 0.0081 15.7 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EJS44598.1 - 0.0091 16.0 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 TGS domain ADH_zinc_N PF00107.26 EJS44599.1 - 2e-09 37.5 0.0 3.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FIBP PF05427.11 EJS44599.1 - 0.0061 15.9 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) DUF4974 PF16344.5 EJS44599.1 - 0.1 12.6 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) CwfJ_C_2 PF04676.14 EJS44599.1 - 0.13 13.2 0.0 0.27 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.25 EJS44600.1 - 1.3e-62 211.6 0.2 5e-61 206.4 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44600.1 - 1.8e-33 115.9 0.0 2.7e-32 112.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EJS44600.1 - 6.5e-06 26.8 0.9 2.1e-05 25.1 0.9 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EJS44600.1 - 0.00041 19.8 0.0 0.011 15.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like TPR_3 PF07720.12 EJS44600.1 - 1.6 8.8 4.9 11 6.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CTP_transf_1 PF01148.20 EJS44601.1 - 2.1e-82 276.9 16.6 2.6e-82 276.6 16.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family SET PF00856.28 EJS44602.1 - 5.2e-08 33.4 0.3 0.00023 21.6 0.0 2.8 3 0 0 3 3 3 2 SET domain Nop14 PF04147.12 EJS44602.1 - 0.015 13.6 5.6 0.024 12.9 5.6 1.3 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 EJS44602.1 - 0.038 14.4 0.0 0.038 14.4 0.0 3.2 2 1 1 3 3 3 0 Centromere protein B dimerisation domain LAT PF15234.6 EJS44602.1 - 0.23 11.2 2.4 0.45 10.2 2.4 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells ATP-synt_ab PF00006.25 EJS44603.1 - 2.1e-72 243.2 0.0 3.2e-72 242.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EJS44603.1 - 1.2e-46 158.1 0.7 2.2e-46 157.3 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EJS44603.1 - 4.3e-16 59.2 1.4 1.2e-15 57.8 1.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Tex_N PF09371.10 EJS44603.1 - 0.051 13.2 0.4 0.61 9.7 0.0 2.3 2 0 0 2 2 2 0 Tex-like protein N-terminal domain FAD_binding_3 PF01494.19 EJS44604.1 - 4.2e-19 69.0 0.0 1.1e-18 67.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EJS44604.1 - 6.6e-07 29.2 0.0 0.00024 20.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 EJS44604.1 - 1.5e-05 24.3 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EJS44604.1 - 1.9e-05 25.1 0.0 0.00054 20.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EJS44604.1 - 6.5e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EJS44604.1 - 7.8e-05 22.8 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 EJS44604.1 - 0.00011 21.4 0.0 0.0014 17.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 EJS44604.1 - 0.00046 19.5 0.0 0.004 16.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EJS44604.1 - 0.0024 17.5 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EJS44604.1 - 0.0048 16.5 0.0 0.0098 15.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 EJS44604.1 - 0.064 12.3 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EJS44604.1 - 0.08 11.6 0.0 0.21 10.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EJS44604.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 EJS44604.1 - 0.21 11.7 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 4HBT PF03061.22 EJS44605.1 - 3.2e-05 24.2 0.0 5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Rox3 PF08633.10 EJS44606.1 - 3.2e-38 132.1 0.3 3.7e-38 131.9 0.3 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit Ribosomal_L32e PF01655.18 EJS44607.1 - 3e-46 156.3 2.3 3.5e-46 156.1 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Peptidase_M24 PF00557.24 EJS44608.1 - 3.5e-53 180.4 0.1 4.5e-53 180.1 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF612 PF04747.12 EJS44608.1 - 0.0022 17.2 3.1 0.003 16.8 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF612 MiaE_2 PF13794.6 EJS44608.1 - 0.16 11.6 0.0 2 8.1 0.0 2.2 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Ribosomal_S21 PF01165.20 EJS44609.1 - 2.2e-10 40.1 2.8 3.3e-10 39.5 1.4 2.0 2 0 0 2 2 2 1 Ribosomal protein S21 Aa_trans PF01490.18 EJS44610.1 - 3.2e-123 411.5 15.3 3.6e-123 411.3 15.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EJS44610.1 - 1.7e-06 27.4 6.8 1.7e-06 27.4 6.8 2.0 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF4228 PF14009.6 EJS44610.1 - 0.25 11.7 0.0 0.39 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF1129 PF06570.11 EJS44610.1 - 5.1 6.5 11.8 8.3 5.8 0.0 4.2 3 3 1 4 4 4 0 Protein of unknown function (DUF1129) NT-C2 PF10358.9 EJS44611.1 - 1.1e-49 167.9 1.4 2e-49 167.1 1.4 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins PH PF00169.29 EJS44612.1 - 4.9e-18 65.6 0.0 4.9e-18 65.6 0.0 3.1 4 0 0 4 4 4 1 PH domain SH3_1 PF00018.28 EJS44612.1 - 8e-13 47.8 0.2 1.5e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 EJS44612.1 - 8.3e-12 45.0 0.0 2.3e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 EJS44612.1 - 5.5e-08 32.5 0.1 1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.6 EJS44612.1 - 8.8e-06 25.9 0.0 0.00039 20.6 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.17 EJS44612.1 - 0.025 14.3 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain SAM_1 PF00536.30 EJS44612.1 - 0.057 13.9 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TPR_2 PF07719.17 EJS44613.1 - 5.7e-38 126.0 8.1 9.2e-07 28.5 0.2 8.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 EJS44613.1 - 1.6e-32 110.0 12.5 7e-09 35.1 0.0 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 EJS44613.1 - 5.1e-31 104.3 12.7 3.3e-05 23.8 0.0 9.3 9 0 0 9 9 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EJS44613.1 - 5.3e-25 87.5 23.7 1.6e-14 53.9 4.2 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EJS44613.1 - 2.5e-22 78.3 14.9 5.9e-06 25.9 0.0 8.6 4 2 5 9 9 9 4 TPR repeat TPR_17 PF13431.6 EJS44613.1 - 2.4e-19 68.3 9.4 9.1e-06 25.7 0.4 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 EJS44613.1 - 1.9e-18 66.8 0.0 1e-07 32.5 0.0 3.8 3 1 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EJS44613.1 - 4.7e-14 51.9 0.0 0.0036 18.0 0.0 6.8 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EJS44613.1 - 1e-13 51.5 2.8 0.0002 21.8 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EJS44613.1 - 5.3e-13 49.1 7.7 0.001 19.3 0.0 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 EJS44613.1 - 8.4e-12 44.9 6.8 0.05 14.3 0.0 6.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EJS44613.1 - 4.1e-09 36.5 0.0 0.0018 18.4 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EJS44613.1 - 2.9e-08 33.2 4.0 1.9 8.7 0.2 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EJS44613.1 - 3.4e-05 23.2 0.0 0.014 14.7 0.0 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 EJS44613.1 - 0.00025 21.3 0.0 0.18 12.1 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EJS44613.1 - 0.0013 18.6 1.5 4.5 7.3 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 EJS44613.1 - 0.0042 17.2 0.0 2.1 8.4 0.0 3.4 3 1 0 3 3 3 1 Domain of Unknown Function (DUF3856) BTAD PF03704.17 EJS44613.1 - 0.074 13.5 0.3 21 5.6 0.2 2.6 1 1 0 2 2 2 0 Bacterial transcriptional activator domain Sel1 PF08238.12 EJS44613.1 - 0.17 12.6 2.5 33 5.4 0.0 4.3 4 0 0 4 4 3 0 Sel1 repeat SRP_TPR_like PF17004.5 EJS44613.1 - 0.53 10.3 3.8 0.28 11.2 0.6 2.3 2 0 0 2 2 2 0 Putative TPR-like repeat Fis1_TPR_C PF14853.6 EJS44613.1 - 4.2 7.5 8.6 5 7.3 0.1 4.6 5 1 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat DUF5349 PF17298.2 EJS44614.1 - 1.9e-142 475.4 70.9 2.2e-142 475.1 70.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5349) DUF5580 PF17743.1 EJS44614.1 - 0.53 8.8 9.1 0.81 8.1 9.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Folate_carrier PF01770.18 EJS44614.1 - 1.3 7.6 3.1 2 7.1 3.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier GatB_N PF02934.15 EJS44615.1 - 7.9e-91 304.2 0.0 9.9e-91 303.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EJS44615.1 - 3.3e-30 104.9 0.0 5.1e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 GatB domain SieB PF14163.6 EJS44615.1 - 0.091 12.3 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B Nucleoporin_N PF08801.11 EJS44616.1 - 6.2e-138 460.2 12.7 1e-137 459.5 12.7 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EJS44616.1 - 1.4e-121 407.1 11.6 6.6e-121 404.9 11.6 1.9 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Atg8 PF02991.16 EJS44617.1 - 9.4e-51 170.3 0.1 1.1e-50 170.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EJS44617.1 - 8.8e-07 29.3 0.0 1.1e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA-synt_1 PF00133.22 EJS44618.1 - 4.6e-247 821.1 0.6 1.7e-246 819.2 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EJS44618.1 - 3.1e-26 92.1 0.0 9.9e-26 90.5 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EJS44618.1 - 3.5e-16 59.0 2.4 1.8e-05 23.7 0.3 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EJS44618.1 - 0.00024 20.6 0.0 0.00078 18.9 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain HSP70 PF00012.20 EJS44619.1 - 2.9e-259 861.3 7.1 3.3e-259 861.1 7.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJS44619.1 - 1.7e-16 59.9 0.1 2e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EJS44619.1 - 0.00039 20.2 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EJS44619.1 - 0.029 13.4 0.4 0.72 8.8 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 EJS44619.1 - 0.034 13.6 0.0 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family PEARLI-4 PF05278.12 EJS44619.1 - 0.035 13.7 2.4 0.051 13.2 0.0 2.0 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) SWI-SNF_Ssr4 PF08549.10 EJS44619.1 - 0.14 10.8 3.8 0.25 9.9 0.1 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Golgin_A5 PF09787.9 EJS44619.1 - 2.3 7.6 7.0 0.97 8.8 2.4 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 Ribosomal_S8e PF01201.22 EJS44620.1 - 4.7e-57 192.0 2.3 6e-57 191.6 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-CSL PF05207.13 EJS44621.1 - 6.1e-22 77.1 0.6 7.9e-22 76.7 0.6 1.2 1 0 0 1 1 1 1 CSL zinc finger ADH_zinc_N_2 PF13602.6 EJS44622.1 - 9.1e-15 55.9 0.0 1.9e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJS44622.1 - 2.1e-05 24.4 0.1 3.9e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJS44622.1 - 0.04 13.9 0.0 0.15 12.1 0.0 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pribosyltran_N PF13793.6 EJS44623.1 - 3.1e-42 143.2 0.2 9.1e-41 138.5 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EJS44623.1 - 2.2e-33 115.8 2.2 5.7e-28 98.2 0.3 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EJS44623.1 - 2.2e-16 59.8 0.7 5.3e-16 58.5 0.7 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EJS44623.1 - 0.00044 19.7 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UCH PF00443.29 EJS44624.1 - 5.2e-63 212.9 0.0 1.2e-62 211.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EJS44624.1 - 3.9e-22 79.3 8.5 3.1e-19 69.7 0.6 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Fungal_trans PF04082.18 EJS44625.1 - 1.6e-24 86.4 2.8 1.6e-24 86.4 2.8 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EJS44625.1 - 4.8e-11 42.6 10.4 8.1e-11 41.9 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.21 EJS44626.1 - 1.7e-31 108.7 0.1 2.8e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 EJS44626.1 - 1e-14 54.1 0.1 1.8e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EJS44626.1 - 9e-11 41.7 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin Cadherin_pro PF08758.11 EJS44626.1 - 0.083 13.1 0.1 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Cadherin prodomain like Kinesin PF00225.23 EJS44627.1 - 4.5e-109 364.4 9.6 4.5e-109 364.4 9.6 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EJS44627.1 - 2.6e-27 95.6 0.4 2.6e-27 95.6 0.4 4.5 3 1 1 4 4 4 1 Microtubule binding Apolipoprotein PF01442.18 EJS44627.1 - 0.0054 16.6 8.1 0.0099 15.8 1.0 3.4 1 1 2 3 3 3 1 Apolipoprotein A1/A4/E domain Prismane PF03063.20 EJS44627.1 - 0.54 8.9 7.9 0.98 8.0 1.7 2.7 2 1 0 3 3 3 0 Prismane/CO dehydrogenase family Sel1 PF08238.12 EJS44628.1 - 7.8e-46 153.5 17.3 9.8e-09 35.6 0.3 7.5 7 0 0 7 7 7 7 Sel1 repeat SEP PF08059.13 EJS44629.1 - 1.3e-22 80.2 0.1 3.5e-22 78.7 0.1 1.8 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EJS44629.1 - 3.6e-17 62.3 0.1 8.9e-17 61.1 0.1 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EJS44629.1 - 2e-09 37.1 1.1 3.8e-09 36.2 1.1 1.5 1 0 0 1 1 1 1 UBA-like domain PP2C PF00481.21 EJS44630.1 - 2.9e-86 289.3 0.0 4.6e-86 288.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-binding PF00249.31 EJS44631.1 - 8.1e-12 45.2 1.3 9.8e-11 41.7 0.1 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EJS44631.1 - 7.6e-09 35.7 4.5 5.2e-08 33.0 0.4 2.9 2 1 0 2 2 2 1 Myb-like DNA-binding domain RRM_1 PF00076.22 EJS44632.1 - 8.4e-07 28.7 0.0 2.2e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 EJS44632.1 - 0.023 14.9 0.1 0.05 13.8 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 DUF3465 PF11948.8 EJS44632.1 - 0.04 13.8 0.1 0.14 12.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) Yippee-Mis18 PF03226.14 EJS44633.1 - 4.9e-16 58.8 4.0 6.2e-16 58.5 4.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EJS44633.1 - 0.0099 16.1 0.7 0.013 15.7 0.7 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I VWA_3_C PF18571.1 EJS44633.1 - 0.18 11.7 0.2 0.25 11.2 0.2 1.2 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain EF-hand_4 PF12763.7 EJS44634.1 - 2.2e-32 111.1 0.0 6.7e-09 35.6 0.1 4.2 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 EJS44634.1 - 3.9e-10 39.4 0.0 1.2e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 EJS44634.1 - 1.4e-08 33.7 0.7 0.0025 17.2 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EJS44634.1 - 5.4e-07 30.0 0.0 0.11 13.0 0.0 4.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EJS44634.1 - 9.4e-07 28.3 0.1 0.34 11.0 0.0 4.5 4 0 0 4 4 4 2 EF-hand domain UBA_4 PF14555.6 EJS44634.1 - 4.3e-05 23.2 0.3 0.00016 21.4 0.3 2.0 1 0 0 1 1 1 1 UBA-like domain TPR_MLP1_2 PF07926.12 EJS44634.1 - 0.011 15.8 64.9 0.095 12.8 24.5 3.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein EF-hand_8 PF13833.6 EJS44634.1 - 0.2 11.5 0.6 16 5.4 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair Atg14 PF10186.9 EJS44634.1 - 0.31 10.1 53.6 0.0052 15.9 17.7 3.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 EJS44634.1 - 1.6 9.2 61.2 0.67 10.5 17.4 4.3 1 1 2 3 3 3 0 Apg6 coiled-coil region Ago_PAZ PF18309.1 EJS44634.1 - 2 9.2 7.2 1.8 9.3 2.5 3.3 2 0 0 2 2 2 0 Argonaute PAZ domain PPP4R2 PF09184.11 EJS44635.1 - 9.9e-76 255.1 11.6 9.9e-76 255.1 11.6 2.0 2 0 0 2 2 2 1 PPP4R2 Peptidase_M16 PF00675.20 EJS44636.1 - 8.7e-31 106.9 0.3 4.2e-30 104.7 0.2 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EJS44636.1 - 2.5e-25 89.5 0.1 7.8e-25 87.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain SDA1 PF05285.12 EJS44637.1 - 0.9 8.9 11.3 1.4 8.3 11.3 1.3 1 0 0 1 1 1 0 SDA1 Proteasome PF00227.26 EJS44638.1 - 2.3e-35 121.8 0.1 1.6e-34 119.0 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit Gemini_AL3 PF01407.17 EJS44638.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Geminivirus AL3 protein CTP_synth_N PF06418.14 EJS44640.1 - 5e-124 412.9 0.2 6.6e-124 412.5 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EJS44640.1 - 8.3e-58 195.3 0.0 1.3e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EJS44640.1 - 0.033 13.9 0.3 0.5 10.1 0.1 2.7 1 1 1 2 2 2 0 Peptidase C26 Ribosomal_L16 PF00252.18 EJS44641.1 - 2.5e-36 124.6 0.1 3.5e-36 124.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Adaptin_N PF01602.20 EJS44642.1 - 1.1e-133 446.5 21.2 1.4e-133 446.2 21.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EJS44642.1 - 1.7e-05 24.9 0.0 5.4e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EJS44642.1 - 0.00016 22.0 0.2 0.00045 20.5 0.2 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain YgbB PF02542.16 EJS44642.1 - 0.13 12.5 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 YgbB family Ala_racemase_N PF01168.20 EJS44643.1 - 8e-18 64.9 0.0 9.6e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Pol_alpha_B_N PF08418.10 EJS44644.1 - 1.4e-67 228.3 8.6 2.5e-67 227.4 8.6 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EJS44644.1 - 8.4e-59 198.4 0.3 1.4e-58 197.7 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B A1_Propeptide PF07966.12 EJS44644.1 - 0.033 14.0 0.3 0.46 10.4 0.0 2.5 2 0 0 2 2 2 0 A1 Propeptide Msap1 PF17077.5 EJS44645.1 - 5.4e-34 117.8 29.4 1.2e-33 116.7 29.4 1.5 1 1 0 1 1 1 1 Mitotic spindle associated protein SHE1 DUF3268 PF11672.8 EJS44645.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 zinc-finger-containing domain Mito_carr PF00153.27 EJS44646.1 - 4.5e-69 228.4 6.1 2.1e-25 88.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zinc_ribbon_15 PF17032.5 EJS44647.1 - 8.9e-06 26.4 0.6 1.3e-05 25.9 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbon family zf-LITAF-like PF10601.9 EJS44647.1 - 0.00076 19.7 0.9 0.0017 18.6 0.9 1.7 1 1 0 1 1 1 1 LITAF-like zinc ribbon domain Rep_1 PF01446.17 EJS44647.1 - 0.014 14.9 0.4 0.018 14.5 0.4 1.2 1 0 0 1 1 1 0 Replication protein RecR PF02132.15 EJS44647.1 - 0.033 13.7 1.1 1 9.0 0.1 2.2 2 0 0 2 2 2 0 RecR protein Zn_Tnp_IS1595 PF12760.7 EJS44647.1 - 0.046 13.7 2.6 0.87 9.6 0.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-Mss51 PF13824.6 EJS44647.1 - 0.057 13.5 2.4 1.6 8.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.6 EJS44647.1 - 3.6 7.1 7.1 5.7 6.5 0.5 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Menin PF05053.13 EJS44648.1 - 4.5 5.5 9.1 0.38 9.1 1.7 2.0 2 0 0 2 2 2 0 Menin Pheromone PF08015.11 EJS44648.1 - 9.1 7.4 22.5 0.27 12.3 2.8 3.1 3 1 0 3 3 3 0 Fungal mating-type pheromone DUF2423 PF10338.9 EJS44649.1 - 1.5e-19 69.9 4.8 1.5e-19 69.9 4.8 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) DUF4241 PF14025.6 EJS44649.1 - 0.0036 17.6 0.0 0.0044 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4241) UAF_Rrn10 PF05234.11 EJS44650.1 - 5.5e-66 220.3 0.3 6.5e-66 220.0 0.3 1.0 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Methyltr_RsmB-F PF01189.17 EJS44651.1 - 7.8e-42 143.2 1.5 2.1e-41 141.8 0.1 2.4 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EJS44651.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase LicD PF04991.13 EJS44651.1 - 0.21 11.7 1.5 0.35 11.0 0.3 2.1 2 0 0 2 2 2 0 LicD family MCM PF00493.23 EJS44652.1 - 2.8e-102 340.5 0.0 4.8e-102 339.8 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EJS44652.1 - 3.8e-36 123.7 0.0 7.1e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EJS44652.1 - 1.6e-26 92.5 0.4 4.2e-26 91.2 0.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 EJS44652.1 - 2e-24 86.6 33.4 2e-24 86.6 33.4 3.9 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 EJS44652.1 - 1.8e-12 47.7 0.1 7e-12 45.9 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EJS44652.1 - 2.6e-09 36.8 0.0 2.9e-07 30.1 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EJS44652.1 - 1.5e-07 31.5 0.0 4.1e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EJS44652.1 - 0.00025 20.9 0.0 0.0016 18.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EJS44652.1 - 0.002 17.9 0.1 0.012 15.3 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 EJS44652.1 - 0.014 15.8 0.0 0.054 13.9 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) SelR PF01641.18 EJS44652.1 - 0.031 14.4 1.7 0.89 9.6 0.1 2.6 3 0 0 3 3 3 0 SelR domain AAA_30 PF13604.6 EJS44652.1 - 0.045 13.5 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain Lon_C PF05362.13 EJS44653.1 - 1.6e-66 223.8 0.0 7.2e-66 221.6 0.0 2.2 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EJS44653.1 - 4.8e-35 121.3 9.1 4.8e-35 121.3 9.1 2.4 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EJS44653.1 - 3.7e-22 79.2 0.0 9.6e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EJS44653.1 - 3.2e-08 33.9 0.0 3.3e-07 30.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EJS44653.1 - 5.8e-07 29.6 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EJS44653.1 - 5.3e-06 26.3 0.1 1.9e-05 24.5 0.0 2.1 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 EJS44653.1 - 0.00025 21.3 0.0 0.0044 17.3 0.0 2.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EJS44653.1 - 0.0018 18.6 0.0 0.083 13.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EJS44653.1 - 0.0023 18.5 0.7 0.014 15.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EJS44653.1 - 0.0025 18.2 0.0 0.014 15.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.11 EJS44653.1 - 0.0027 16.7 0.0 0.0058 15.6 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_14 PF13173.6 EJS44653.1 - 0.0045 17.0 0.1 0.038 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EJS44653.1 - 0.007 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 EJS44653.1 - 0.0099 15.6 0.0 0.044 13.5 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain SKI PF01202.22 EJS44653.1 - 0.028 14.6 0.0 0.1 12.7 0.0 2.1 1 0 0 1 1 1 0 Shikimate kinase RsgA_GTPase PF03193.16 EJS44653.1 - 0.042 13.7 0.0 0.2 11.5 0.0 2.2 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 EJS44653.1 - 0.047 13.6 0.8 1.1 9.1 0.1 3.0 2 1 1 3 3 3 0 NTPase TsaE PF02367.17 EJS44653.1 - 0.065 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EJS44653.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EJS44653.1 - 0.15 11.5 0.3 0.42 10.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EJS44653.1 - 1.7 9.2 4.7 1.8 9.1 0.0 3.1 3 1 0 3 3 3 0 ABC transporter CBFD_NFYB_HMF PF00808.23 EJS44654.1 - 6e-25 87.3 0.0 8.6e-25 86.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EJS44654.1 - 0.00017 21.9 0.0 0.00023 21.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Rft-1 PF04506.13 EJS44655.1 - 2.8e-215 715.9 34.6 3.1e-215 715.7 34.6 1.0 1 0 0 1 1 1 1 Rft protein Exo_endo_phos PF03372.23 EJS44656.1 - 3.8e-13 49.5 0.0 7.5e-13 48.5 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EJS44656.1 - 4.4e-11 42.7 2.8 9.2e-11 41.7 2.8 1.6 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 EJS44656.1 - 1.6e-06 27.9 0.0 0.033 14.0 0.0 2.7 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase RNA_pol_Rpb1_6 PF04992.14 EJS44656.1 - 0.13 12.1 1.2 0.33 10.8 0.8 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 6 Sortilin-Vps10 PF15902.5 EJS44657.1 - 5.1e-213 707.8 25.4 1.5e-143 478.8 5.8 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EJS44657.1 - 3.8e-72 242.2 24.0 3.7e-40 138.1 3.7 3.2 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EJS44657.1 - 1.3e-14 51.7 48.5 0.12 12.4 0.3 14.2 14 0 0 14 14 14 9 BNR/Asp-box repeat PSII_BNR PF14870.6 EJS44657.1 - 0.00029 20.2 0.8 1 8.6 0.1 4.5 4 1 0 4 4 4 2 Photosynthesis system II assembly factor YCF48 CHB_HEX_C PF03174.13 EJS44657.1 - 0.00039 20.3 4.2 2.5 8.2 0.1 5.1 5 0 0 5 5 5 2 Chitobiase/beta-hexosaminidase C-terminal domain Mo-co_dimer PF03404.16 EJS44657.1 - 0.18 11.8 6.4 7.8 6.5 0.0 5.4 6 1 0 6 6 6 0 Mo-co oxidoreductase dimerisation domain Pkinase PF00069.25 EJS44658.1 - 2.8e-68 230.2 0.0 3.3e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44658.1 - 5.2e-31 107.9 0.0 7.2e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EJS44658.1 - 0.0043 16.1 1.6 0.012 14.6 1.5 1.5 1 1 1 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EJS44658.1 - 0.017 14.5 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EJS44658.1 - 0.026 13.8 0.0 0.064 12.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EJS44658.1 - 0.09 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AcetylCoA_hydro PF02550.15 EJS44659.1 - 4.3e-78 261.8 0.1 1.3e-77 260.2 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EJS44659.1 - 6.4e-40 136.6 0.0 9.6e-40 136.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.12 EJS44659.1 - 0.0052 15.7 0.1 0.012 14.5 0.1 1.5 1 1 0 1 1 1 1 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.23 EJS44659.1 - 0.053 12.9 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Coenzyme A transferase Cid2 PF09774.9 EJS44660.1 - 4e-41 141.1 5.6 5.2e-41 140.7 5.6 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Lgl_C PF08596.10 EJS44661.1 - 9.7e-146 485.5 0.7 9e-145 482.3 0.0 2.5 2 1 1 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 EJS44661.1 - 3.5e-09 36.8 1.2 0.0047 17.2 0.0 5.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EJS44661.1 - 1.1e-06 29.2 0.5 1.4 9.9 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40_like PF17005.5 EJS44661.1 - 0.00028 20.3 3.0 0.00047 19.6 1.1 2.1 2 0 0 2 2 2 1 WD40-like domain Pkinase PF00069.25 EJS44662.1 - 1.1e-61 208.5 0.1 2.6e-60 204.0 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44662.1 - 4.6e-36 124.4 0.0 1.1e-35 123.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EJS44662.1 - 3.8e-20 71.5 36.7 1.7e-11 43.8 15.1 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 EJS44662.1 - 8.3e-19 67.5 24.3 6.5e-11 42.2 7.3 3.6 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 EJS44662.1 - 6.4e-13 49.2 2.9 6.4e-13 49.2 2.9 3.5 4 0 0 4 4 3 1 Protein kinase C terminal domain C2 PF00168.30 EJS44662.1 - 2.4e-05 24.5 0.0 7.7e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EJS44662.1 - 0.00027 20.4 1.5 0.00077 18.9 0.0 2.5 2 1 1 3 3 3 1 Kinase-like Uds1 PF15456.6 EJS44662.1 - 0.0075 16.4 0.5 0.0075 16.4 0.5 4.2 4 0 0 4 4 4 2 Up-regulated During Septation FliC PF12445.8 EJS44662.1 - 0.017 15.5 4.2 0.61 10.4 0.5 2.7 2 0 0 2 2 2 0 Flagellin protein B2-adapt-app_C PF09066.10 EJS44662.1 - 0.05 13.7 0.0 0.18 11.9 0.0 2.0 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain zf-RING_9 PF13901.6 EJS44662.1 - 0.47 10.4 31.2 0.64 10.0 7.6 3.5 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon zinc_ribbon_16 PF17034.5 EJS44663.1 - 6.8e-26 90.9 6.6 6.8e-26 90.9 6.6 2.4 3 0 0 3 3 3 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EJS44663.1 - 3.7e-06 26.5 6.6 3.7e-06 26.5 6.6 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Occludin_ELL PF07303.13 EJS44663.1 - 0.0069 17.1 0.0 0.1 13.3 0.0 2.7 2 0 0 2 2 2 1 Occludin homology domain WD40 PF00400.32 EJS44663.1 - 0.021 15.7 0.6 4.3 8.4 0.1 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat HLH PF00010.26 EJS44664.1 - 1.6e-13 50.4 0.4 3.4e-13 49.3 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DASH_Dad3 PF08656.10 EJS44664.1 - 0.032 14.3 0.4 0.11 12.6 0.4 1.9 1 0 0 1 1 1 0 DASH complex subunit Dad3 3H PF02829.14 EJS44664.1 - 0.1 12.9 0.3 0.3 11.4 0.3 1.7 1 0 0 1 1 1 0 3H domain YebO PF13974.6 EJS44664.1 - 0.2 11.8 1.7 1.2 9.2 0.3 2.5 2 0 0 2 2 2 0 YebO-like protein Got1 PF04178.12 EJS44665.1 - 1.2e-31 109.5 18.5 1.2e-31 109.5 18.5 1.4 2 0 0 2 2 2 1 Got1/Sft2-like family ABC2_membrane_3 PF12698.7 EJS44665.1 - 0.021 14.0 9.9 0.024 13.8 9.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2207 PF09972.9 EJS44665.1 - 2.7 6.7 9.4 61 2.2 9.4 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2070 PF09843.9 EJS44665.1 - 9 4.4 10.2 11 4.1 10.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Arrestin_C PF02752.22 EJS44666.1 - 4e-06 27.3 10.2 6.8e-06 26.6 5.1 3.4 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain MFS_1 PF07690.16 EJS44667.1 - 1.6e-29 102.9 15.3 2.3e-29 102.4 15.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cornichon PF03311.14 EJS44668.1 - 7.9e-42 142.4 9.5 9.4e-42 142.2 9.5 1.0 1 0 0 1 1 1 1 Cornichon protein APG6_N PF17675.1 EJS44669.1 - 0.13 12.8 5.0 0.072 13.6 2.9 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region Med8 PF10232.9 EJS44669.1 - 0.14 11.7 2.4 0.31 10.6 2.4 1.5 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 FAM167 PF11652.8 EJS44669.1 - 0.17 12.3 2.3 0.26 11.8 0.9 2.0 1 1 1 2 2 2 0 FAM167 DivIC PF04977.15 EJS44669.1 - 8.6 6.2 8.3 0.85 9.4 3.1 2.0 2 1 0 2 2 2 0 Septum formation initiator NAD_binding_7 PF13241.6 EJS44670.1 - 1.6e-26 92.7 0.0 3e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EJS44670.1 - 2.7e-17 62.1 0.0 5.6e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EJS44670.1 - 7.8e-11 41.2 0.0 1.5e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central HU-CCDC81_bac_1 PF18174.1 EJS44670.1 - 0.016 15.1 0.0 0.057 13.3 0.0 1.8 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 1 MUG113 PF13455.6 EJS44670.1 - 0.053 14.2 0.3 4.2 8.1 0.0 3.0 2 1 1 3 3 3 0 Meiotically up-regulated gene 113 Shikimate_DH PF01488.20 EJS44670.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 EJS44670.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EJS44670.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CBS PF00571.28 EJS44671.1 - 1.7e-20 73.2 1.8 8.5e-07 29.3 0.0 5.3 5 0 0 5 5 5 5 CBS domain Kinetochor_Ybp2 PF08568.10 EJS44672.1 - 5.5e-152 507.5 11.6 6.6e-152 507.2 11.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin APG12 PF04110.13 EJS44673.1 - 2.5e-35 120.7 0.5 6.3e-35 119.4 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 DUF2575 PF10837.8 EJS44673.1 - 0.069 13.5 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) Glyco_transf_7N PF13733.6 EJS44673.1 - 0.071 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 CPSase_L_D2 PF02786.17 EJS44674.1 - 7.4e-84 280.5 0.1 1.4e-83 279.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EJS44674.1 - 4.3e-69 232.2 0.0 6.8e-69 231.6 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EJS44674.1 - 5.6e-39 133.1 0.0 1.4e-38 131.9 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EJS44674.1 - 4.2e-31 107.2 0.0 1.1e-30 105.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EJS44674.1 - 6.6e-27 94.7 0.1 1.5e-26 93.6 0.1 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EJS44674.1 - 3.9e-19 68.3 5.3 3.9e-19 68.3 5.3 2.7 3 0 0 3 3 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EJS44674.1 - 8.3e-07 28.7 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EJS44674.1 - 1.6e-06 27.8 6.6 0.013 15.3 0.1 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 EJS44674.1 - 6.1e-06 25.9 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EJS44674.1 - 2.9e-05 24.1 0.0 7.8e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 EJS44674.1 - 0.00031 20.0 0.6 0.0043 16.3 0.2 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 EJS44674.1 - 0.0032 17.1 0.0 0.0069 16.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EJS44674.1 - 0.012 14.9 0.0 0.028 13.6 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 EJS44674.1 - 0.031 15.0 2.3 13 6.5 0.0 3.6 3 0 0 3 3 3 0 HlyD family secretion protein RnfC_N PF13375.6 EJS44674.1 - 0.075 13.0 4.8 0.36 10.8 1.9 2.8 3 0 0 3 3 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EJS44674.1 - 0.16 11.9 0.5 0.38 10.6 0.5 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein Acatn PF13000.7 EJS44675.1 - 1.1e-282 938.5 13.3 1.2e-282 938.3 13.3 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Transket_pyr PF02779.24 EJS44676.1 - 4.4e-47 160.0 0.0 1.2e-46 158.6 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EJS44676.1 - 3.1e-37 127.2 0.1 5.7e-37 126.3 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EJS44676.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II AMP-binding PF00501.28 EJS44677.1 - 2.2e-71 240.7 0.0 3.3e-71 240.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJS44677.1 - 8.4e-20 71.5 0.3 5.7e-19 68.9 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NSP11 PF06471.12 EJS44677.1 - 0.093 11.2 0.0 0.16 10.4 0.0 1.4 1 0 0 1 1 1 0 NSP11 Tyr-DNA_phospho PF06087.12 EJS44678.1 - 8.6e-96 321.4 0.0 1.1e-95 321.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EJS44678.1 - 0.015 15.2 0.0 0.7 9.8 0.0 2.4 2 0 0 2 2 2 0 PLD-like domain Methyltransf_11 PF08241.12 EJS44679.1 - 0.0054 17.3 0.0 0.023 15.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS44679.1 - 0.069 13.9 0.0 4.6 8.0 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain GIY-YIG PF01541.24 EJS44680.1 - 4e-14 52.7 0.0 9.9e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 EJS44680.1 - 8.4e-06 25.9 4.2 2.7e-05 24.2 4.2 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EJS44680.1 - 0.038 14.3 4.9 0.13 12.6 4.9 2.0 1 1 0 1 1 1 0 Ring finger domain YacG PF03884.14 EJS44680.1 - 0.13 12.0 2.6 8.1 6.3 0.2 2.6 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-RING-like PF08746.11 EJS44680.1 - 0.33 11.3 9.1 3.8 7.9 9.1 2.5 1 1 0 1 1 1 0 RING-like domain Glyco_hydro_31 PF01055.26 EJS44681.1 - 4.8e-132 441.3 1.9 1e-131 440.2 1.9 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EJS44681.1 - 3.4e-22 78.5 0.5 1.8e-21 76.2 0.2 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EJS44681.1 - 2.5e-07 30.9 0.0 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) KH_1 PF00013.29 EJS44683.1 - 4.7e-39 132.0 3.5 9.4e-13 47.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EJS44683.1 - 1e-09 38.1 0.3 0.035 13.9 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EJS44683.1 - 5.1e-07 29.5 0.3 0.046 13.6 0.0 3.2 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 EJS44683.1 - 0.003 17.6 1.5 8.9 6.5 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain DUF3464 PF11947.8 EJS44683.1 - 0.11 12.2 0.0 8.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 WD40 PF00400.32 EJS44684.1 - 2.2e-10 41.0 6.2 0.005 17.7 0.2 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44684.1 - 3.8e-08 33.5 0.0 0.026 14.8 0.0 4.5 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EJS44684.1 - 0.012 15.5 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A AA_permease PF00324.21 EJS44685.1 - 1e-45 156.3 40.0 1.6e-45 155.6 40.0 1.3 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EJS44685.1 - 4.6e-17 62.2 3.4 5.5e-08 32.3 0.0 3.3 2 1 1 3 3 3 3 Solute carrier family 12 Menin PF05053.13 EJS44686.1 - 0.083 11.2 4.9 0.17 10.2 4.9 1.4 1 0 0 1 1 1 0 Menin Zip PF02535.22 EJS44686.1 - 0.23 10.6 9.7 0.35 10.0 9.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 EJS44686.1 - 4.3 7.3 6.4 0.73 9.9 2.6 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 EJS44686.1 - 8.9 4.7 12.2 14 4.0 12.2 1.3 1 0 0 1 1 1 0 Macoilin family PAS PF00989.25 EJS44687.1 - 4.4e-18 65.3 0.0 7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 EJS44687.1 - 2e-05 24.6 11.0 4e-05 23.6 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.10 EJS44687.1 - 0.19 12.0 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 PAS fold Zn_clus PF00172.18 EJS44688.1 - 2.4e-11 43.6 6.0 2.4e-11 43.6 6.0 2.7 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YjbE PF11106.8 EJS44688.1 - 2 8.7 9.3 3.3 8.0 9.3 1.3 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Sugar_tr PF00083.24 EJS44689.1 - 5.2e-116 388.2 23.5 6.1e-116 387.9 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EJS44689.1 - 8.5e-28 97.3 34.8 1e-27 97.0 28.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glycos_transf_4 PF00953.21 EJS44690.1 - 6.2e-34 117.3 9.0 6.2e-34 117.3 9.0 2.3 3 1 0 3 3 3 1 Glycosyl transferase family 4 GSHPx PF00255.19 EJS44691.1 - 7.9e-51 170.2 2.5 1.1e-50 169.8 2.5 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EJS44691.1 - 3.1e-06 27.1 0.5 1.3e-05 25.1 0.5 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EJS44691.1 - 9.1e-05 22.2 0.1 0.0004 20.1 0.1 1.9 1 1 0 1 1 1 1 Redoxin WD40 PF00400.32 EJS44692.1 - 0.0069 17.2 4.5 31 5.7 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Cyclase PF04199.13 EJS44692.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.8 1 1 0 1 1 1 0 Putative cyclase DUF2415 PF10313.9 EJS44692.1 - 0.17 11.8 0.0 0.76 9.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Bystin PF05291.11 EJS44693.1 - 1.2e-120 402.3 0.0 1.7e-120 401.7 0.0 1.2 1 0 0 1 1 1 1 Bystin DAHP_synth_1 PF00793.20 EJS44694.1 - 1e-110 369.0 0.0 1.2e-110 368.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_S5_C PF03719.15 EJS44695.1 - 2.8e-22 77.9 0.0 4.7e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EJS44695.1 - 4.6e-22 77.8 0.2 9.8e-22 76.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain dUTPase PF00692.19 EJS44696.1 - 3.6e-46 156.0 0.1 4.1e-46 155.8 0.1 1.0 1 0 0 1 1 1 1 dUTPase FtsZ_C PF12327.8 EJS44696.1 - 0.067 13.5 0.1 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 FtsZ family, C-terminal domain Med22 PF06179.12 EJS44697.1 - 1.9e-20 73.0 6.6 2.2e-20 72.8 6.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex GCIP PF13324.6 EJS44697.1 - 0.022 14.4 2.5 0.025 14.2 2.5 1.0 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Sedlin_N PF04628.13 EJS44698.1 - 2.1e-53 179.9 0.0 2.5e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EJS44698.1 - 2.7e-07 30.6 0.2 4.8e-07 29.8 0.2 1.7 1 1 0 1 1 1 1 Sybindin-like family Lum_binding PF00677.17 EJS44700.1 - 5.8e-43 144.8 2.4 5e-21 74.5 1.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain UPF0086 PF01868.16 EJS44701.1 - 8.5e-23 80.1 0.0 1.4e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 F_actin_bind PF08919.10 EJS44701.1 - 0.27 11.3 3.8 0.81 9.8 3.8 1.9 1 1 0 1 1 1 0 F-actin binding Methyltransf_PK PF05891.12 EJS44703.1 - 3.3e-99 330.8 0.0 3.7e-99 330.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EJS44703.1 - 6.1e-07 30.1 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJS44703.1 - 3.2e-06 27.1 0.0 6.9e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EJS44703.1 - 0.0047 16.2 0.1 0.009 15.3 0.1 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 EJS44703.1 - 0.0088 16.7 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EJS44703.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Secretin_N_2 PF07655.13 EJS44703.1 - 0.14 12.7 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Methyltransf_12 PF08242.12 EJS44703.1 - 0.16 12.8 0.0 0.35 11.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain AIM5 PF17050.5 EJS44704.1 - 3.4e-06 27.8 0.2 4.7e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 SHMT PF00464.19 EJS44705.1 - 5.6e-209 693.7 0.0 6.5e-209 693.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EJS44705.1 - 0.019 14.1 0.0 0.042 13.0 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class I and II Arnt_C PF18583.1 EJS44705.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain Ras PF00071.22 EJS44706.1 - 8.7e-40 136.0 0.0 1e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EJS44706.1 - 2.9e-33 114.6 0.0 4.1e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EJS44706.1 - 1.1e-10 41.2 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EJS44706.1 - 6.6e-07 29.1 0.2 4.3e-06 26.4 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EJS44706.1 - 7.9e-07 28.7 0.0 2.1e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EJS44706.1 - 8.8e-05 22.5 0.3 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EJS44706.1 - 0.00093 19.3 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EJS44706.1 - 0.011 14.9 0.1 0.97 8.5 0.1 2.6 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 EJS44706.1 - 0.024 14.7 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EJS44706.1 - 0.054 13.0 0.0 1 8.9 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 EJS44706.1 - 0.061 13.7 0.2 0.15 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EJS44706.1 - 0.068 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit adh_short PF00106.25 EJS44707.1 - 1.9e-21 76.4 0.0 5.9e-13 48.7 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 EJS44707.1 - 1.1e-09 38.4 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EJS44707.1 - 1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 EJS44707.1 - 0.001 18.3 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1788 PF08747.11 EJS44707.1 - 0.036 14.1 0.0 0.15 12.1 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1788) zf-C2H2_2 PF12756.7 EJS44708.1 - 1.1e-32 112.4 6.8 2.2e-31 108.2 1.5 2.6 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) PP_kinase_C PF13090.6 EJS44708.1 - 0.045 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 DUF2024 PF09630.10 EJS44708.1 - 0.1 12.5 0.1 0.33 10.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) NOA36 PF06524.12 EJS44708.1 - 0.45 9.8 9.7 1.5 8.1 0.3 2.3 2 0 0 2 2 2 0 NOA36 protein FRG1 PF06229.12 EJS44708.1 - 1.2 8.8 9.0 1.9 8.2 7.6 2.0 2 0 0 2 2 2 0 FRG1-like domain Presenilin PF01080.17 EJS44708.1 - 1.4 7.6 2.5 1.9 7.2 2.5 1.2 1 0 0 1 1 1 0 Presenilin Ribosomal_L37 PF08561.10 EJS44709.1 - 5e-20 72.2 10.7 4.3e-16 59.5 0.6 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 DUF1674 PF07896.12 EJS44710.1 - 1.1e-18 67.5 1.4 1.9e-18 66.6 1.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) HbrB PF08539.11 EJS44711.1 - 1.9e-33 115.9 2.3 1.6e-32 112.9 2.3 2.3 1 1 0 1 1 1 1 HbrB-like DED PF01335.21 EJS44711.1 - 0.17 12.2 0.5 3.9 7.8 0.0 3.1 4 0 0 4 4 4 0 Death effector domain Methyltransf_16 PF10294.9 EJS44712.1 - 3.5e-25 88.7 0.0 5e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EJS44712.1 - 4.1e-07 30.0 0.0 3.5e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJS44712.1 - 9e-07 28.8 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS44712.1 - 0.0015 19.2 0.0 0.0033 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EJS44712.1 - 0.003 18.3 0.0 0.0092 16.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EJS44712.1 - 0.0031 17.2 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TRM PF02005.16 EJS44712.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DREV PF05219.12 EJS44712.1 - 0.034 13.3 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 EJS44712.1 - 0.034 13.7 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 EJS44712.1 - 0.062 14.0 0.0 0.15 12.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 EJS44713.1 - 1.1e-61 208.5 0.0 1.4e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44713.1 - 1.6e-34 119.4 0.0 2.3e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS44713.1 - 1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EJS44713.1 - 2.2e-05 23.4 0.0 3.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EJS44713.1 - 0.0043 16.0 0.0 0.0062 15.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EJS44713.1 - 0.0063 15.6 0.1 0.018 14.1 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Choline_kinase PF01633.20 EJS44713.1 - 0.031 13.8 0.1 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 EJS44713.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSPc PF00782.20 EJS44714.1 - 5.2e-26 91.0 0.0 2.9e-21 75.7 0.1 3.6 2 1 1 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EJS44714.1 - 0.00013 21.7 0.1 0.00057 19.5 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EJS44714.1 - 0.033 14.3 0.3 0.092 12.9 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 EJS44714.1 - 0.045 14.0 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Rit1 DUSP-like domain RCC1_2 PF13540.6 EJS44715.1 - 1e-19 69.8 12.8 1.3e-10 40.8 1.9 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EJS44715.1 - 1.1e-16 61.1 6.6 1.5e-05 25.5 0.3 6.1 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 EJS44715.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 F-box-like Peptidase_M20 PF01546.28 EJS44716.1 - 1.7e-19 70.4 0.0 2.9e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EJS44716.1 - 2.1e-14 53.4 0.0 3.7e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 EJS44716.1 - 2.2e-12 47.3 1.8 0.0038 18.0 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44716.1 - 0.0015 18.8 0.0 2.9 8.2 0.0 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain MRP-L27 PF09809.9 EJS44717.1 - 1.1e-32 112.2 0.2 1.5e-32 111.7 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SecY PF00344.20 EJS44718.1 - 3.8e-42 144.6 21.5 5.1e-42 144.2 21.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EJS44718.1 - 1.1e-09 38.0 0.1 1.1e-09 38.0 0.1 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p DUF99 PF01949.16 EJS44718.1 - 0.12 11.7 0.2 0.23 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 Cas_Csn2 PF09711.10 EJS44718.1 - 0.16 11.6 0.4 0.27 10.8 0.4 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) A_deaminase PF00962.22 EJS44719.1 - 7.4e-28 97.8 0.0 3.5e-26 92.3 0.0 2.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Peptidase_M28 PF04389.17 EJS44721.1 - 2.3e-41 141.7 0.2 3.4e-41 141.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EJS44721.1 - 1.2e-08 34.9 0.0 2.9e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EJS44721.1 - 0.003 17.3 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EJS44721.1 - 0.034 13.2 0.0 0.068 12.2 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Mem_trans PF03547.18 EJS44722.1 - 7.5e-76 255.0 11.9 1.4e-75 254.1 11.9 1.4 1 1 0 1 1 1 1 Membrane transport protein FixS PF03597.15 EJS44722.1 - 0.18 11.5 5.5 5.2 6.9 0.3 3.6 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Adap_comp_sub PF00928.21 EJS44723.1 - 3e-44 151.4 0.1 4.3e-44 150.9 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF3947 PF13135.6 EJS44723.1 - 0.094 12.9 2.3 0.19 12.0 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Mito_carr PF00153.27 EJS44724.1 - 2.7e-63 209.9 1.6 4.5e-21 74.6 0.5 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EJS44724.1 - 0.007 15.5 1.6 3.5 6.7 0.0 3.0 2 1 0 3 3 3 2 Gammaproteobacterial serine protease Tim17 PF02466.19 EJS44724.1 - 0.068 13.6 3.3 9.2 6.7 0.8 3.5 1 1 3 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family PHO4 PF01384.20 EJS44725.1 - 1.7e-117 392.2 17.3 2.1e-117 392.0 17.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family Tautomerase PF01361.21 EJS44725.1 - 0.0049 16.8 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 Tautomerase enzyme SRF-TF PF00319.18 EJS44726.1 - 1.2e-21 75.9 0.1 2.2e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FAM199X PF15814.5 EJS44726.1 - 0.085 11.9 1.4 0.13 11.3 1.4 1.3 1 0 0 1 1 1 0 Protein family FAM199X MBA1 PF07961.11 EJS44727.1 - 7.6e-109 362.3 1.0 9.2e-109 362.0 1.0 1.0 1 0 0 1 1 1 1 MBA1-like protein UPF0016 PF01169.19 EJS44728.1 - 2.7e-38 130.1 31.9 2.4e-20 72.6 9.1 2.7 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 DUF2448 PF10476.9 EJS44728.1 - 1.6 8.6 4.7 3 7.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) cwf18 PF08315.12 EJS44729.1 - 0.00046 20.9 11.1 0.0097 16.6 11.1 2.1 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor MRP-S22 PF10245.9 EJS44729.1 - 0.23 11.2 5.2 0.044 13.5 2.1 1.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S22 Mito_carr PF00153.27 EJS44730.1 - 1e-74 246.6 3.2 5e-28 96.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PGI PF00342.19 EJS44731.1 - 4e-248 823.9 2.8 4.7e-248 823.6 2.8 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase WD40 PF00400.32 EJS44732.1 - 5e-51 169.6 20.6 1.2e-09 38.7 0.3 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EJS44732.1 - 2.5e-42 144.2 1.9 4.9e-42 143.2 1.9 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EJS44732.1 - 7.7e-13 48.6 0.0 0.13 12.5 0.0 6.1 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EJS44732.1 - 8.2e-07 28.8 0.1 2.1e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 EJS44732.1 - 4.5e-06 26.2 0.0 0.76 9.0 0.0 3.4 3 0 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 EJS44732.1 - 2e-05 23.7 0.0 0.23 10.4 0.0 3.6 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EJS44732.1 - 0.00011 21.0 0.3 0.0088 14.8 0.3 2.9 1 1 0 1 1 1 1 Nup133 N terminal like Nup160 PF11715.8 EJS44732.1 - 0.002 16.9 5.3 0.39 9.3 0.1 3.9 3 2 0 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EJS44732.1 - 0.0039 15.8 0.1 0.17 10.4 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 EJS44732.1 - 0.024 14.6 0.0 3.5 7.7 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 EJS44732.1 - 0.13 12.1 0.0 11 6.0 0.0 3.3 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat Glyco_transf_15 PF01793.16 EJS44733.1 - 4e-106 354.9 14.6 5.2e-106 354.6 14.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SH3_1 PF00018.28 EJS44734.1 - 1.1e-25 89.0 0.0 4.6e-12 45.3 0.0 2.6 2 0 0 2 2 2 2 SH3 domain PX PF00787.24 EJS44734.1 - 3.5e-18 65.6 0.0 6.6e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.6 EJS44734.1 - 1.7e-14 53.4 0.4 1.2e-10 41.0 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 EJS44734.1 - 1.4e-07 31.0 0.0 6.9e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain PB1 PF00564.24 EJS44734.1 - 0.00079 19.3 0.0 0.0024 17.8 0.0 1.8 1 0 0 1 1 1 1 PB1 domain DER1 PF04511.15 EJS44735.1 - 9.3e-52 175.7 9.2 1.1e-51 175.6 9.2 1.0 1 0 0 1 1 1 1 Der1-like family MCM PF00493.23 EJS44737.1 - 6e-103 342.8 0.0 9e-103 342.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EJS44737.1 - 2e-31 108.4 0.7 3.6e-31 107.6 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EJS44737.1 - 1.2e-21 76.9 2.5 1.3e-21 76.7 0.4 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EJS44737.1 - 6e-13 49.3 6.9 3.2e-12 46.9 6.9 2.3 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EJS44737.1 - 9.2e-08 31.7 0.0 1.1e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EJS44737.1 - 1.3e-06 28.5 0.0 5.7e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EJS44737.1 - 0.0023 17.7 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase_C PF13335.6 EJS44737.1 - 0.0082 16.8 2.1 0.022 15.4 0.2 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 EJS44737.1 - 0.045 13.6 0.0 0.15 12.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EJS44737.1 - 0.056 13.1 0.0 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 EJS44737.1 - 0.12 12.8 0.2 3.7 7.9 0.0 3.0 1 1 0 2 2 2 0 AAA ATPase domain FTR1 PF03239.14 EJS44738.1 - 4.9e-113 377.3 3.3 5.7e-113 377.1 3.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Amidase_5 PF05382.13 EJS44738.1 - 0.018 15.0 1.4 0.023 14.6 0.3 1.7 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase S_2TMBeta PF18153.1 EJS44738.1 - 0.035 13.9 2.7 0.06 13.1 0.8 2.2 2 0 0 2 2 2 0 SMODS-associating 2TM, beta-strand rich effector domain DUF3149 PF11346.8 EJS44738.1 - 0.57 9.8 6.8 0.14 11.8 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) CASP_C PF08172.12 EJS44738.1 - 1.5 8.1 4.2 3.3 7.0 4.2 1.5 1 0 0 1 1 1 0 CASP C terminal Amidase PF01425.21 EJS44739.1 - 1.2e-103 347.6 0.0 1.6e-103 347.1 0.0 1.2 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 EJS44739.1 - 2.6e-86 289.5 0.0 5.1e-86 288.6 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 EJS44739.1 - 4.3e-63 212.6 0.0 8.2e-63 211.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 EJS44739.1 - 1.3e-42 145.9 0.0 2.4e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 EJS44739.1 - 2.3e-41 140.8 0.0 5.6e-41 139.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EJS44739.1 - 8.4e-32 109.5 0.0 2.4e-31 108.0 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EJS44739.1 - 1.1e-18 66.9 0.6 3.1e-18 65.4 0.6 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EJS44739.1 - 6e-12 45.5 0.0 1.4e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EJS44739.1 - 1e-05 25.2 0.0 2.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EJS44739.1 - 0.00033 20.7 0.0 0.00064 19.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 EJS44739.1 - 0.007 15.8 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 EJS44739.1 - 0.021 14.8 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 EJS44739.1 - 0.09 12.6 0.4 0.86 9.5 0.0 2.6 1 1 1 2 2 2 0 Biotin-lipoyl like RimK PF08443.11 EJS44739.1 - 0.11 12.1 0.0 0.41 10.2 0.0 1.9 1 1 0 1 1 1 0 RimK-like ATP-grasp domain DUF1351 PF07083.11 EJS44740.1 - 0.029 14.2 0.1 0.037 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Ribosomal_L31 PF01197.18 EJS44741.1 - 0.0056 16.9 0.0 0.0096 16.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 YqzE PF14038.6 EJS44741.1 - 0.077 13.0 0.1 0.077 13.0 0.1 1.9 3 0 0 3 3 3 0 YqzE-like protein PP2C PF00481.21 EJS44742.1 - 6.3e-73 245.6 0.0 2.4e-69 233.8 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EJS44742.1 - 0.041 13.5 0.0 0.16 11.6 0.0 2.1 1 1 0 1 1 1 0 Protein phosphatase 2C Glyco_transf_20 PF00982.21 EJS44743.1 - 7.3e-203 674.5 0.1 8.3e-203 674.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 EJS44743.1 - 0.0004 20.0 0.4 0.053 13.1 0.1 3.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EJS44743.1 - 0.00097 19.6 0.0 0.0025 18.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 ATP-synt_ab PF00006.25 EJS44744.1 - 2e-66 223.7 0.0 3.1e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EJS44744.1 - 4.6e-16 59.1 1.1 9.6e-16 58.1 1.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Atg14 PF10186.9 EJS44745.1 - 3.3e-29 102.0 3.5 6.9e-29 100.9 3.5 1.4 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Leu_zip PF15294.6 EJS44745.1 - 0.00018 21.2 5.6 0.00025 20.7 5.6 1.1 1 0 0 1 1 1 1 Leucine zipper Not3 PF04065.15 EJS44745.1 - 0.0044 16.5 3.8 0.0062 16.0 3.8 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Phage_HK97_TLTM PF06120.11 EJS44745.1 - 0.02 14.1 4.4 0.036 13.3 3.5 1.6 1 1 0 1 1 1 0 Tail length tape measure protein Laminin_II PF06009.12 EJS44745.1 - 0.41 10.7 5.2 0.39 10.7 3.6 1.7 1 1 0 1 1 1 0 Laminin Domain II DUF3896 PF13035.6 EJS44745.1 - 0.45 10.7 6.1 12 6.1 2.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3896) zf-C4pol PF14260.6 EJS44745.1 - 1.7 9.2 5.4 5 7.7 0.4 2.9 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta FlaC_arch PF05377.11 EJS44745.1 - 3.8 8.0 7.3 4.9 7.6 0.5 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 EJS44745.1 - 7.9 6.7 9.0 20 5.4 1.0 2.7 2 0 0 2 2 2 0 Basic region leucine zipper PH PF00169.29 EJS44746.1 - 5.1e-10 39.8 6.5 3.2e-07 30.8 0.9 2.6 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 EJS44746.1 - 0.012 16.0 8.8 0.75 10.2 0.2 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain Receptor_2B4 PF11465.8 EJS44746.1 - 0.46 10.7 3.1 2.7 8.2 1.7 2.3 1 1 1 2 2 2 0 Natural killer cell receptor 2B4 DUF1712 PF08217.11 EJS44747.1 - 5.9e-200 665.8 26.4 6.7e-200 665.6 26.4 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) AA_permease PF00324.21 EJS44748.1 - 7.4e-138 460.1 24.3 8.5e-138 459.9 24.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS44748.1 - 5.1e-26 91.5 27.7 6e-26 91.2 27.7 1.1 1 0 0 1 1 1 1 Amino acid permease PRMT5_TIM PF17285.2 EJS44749.1 - 4.1e-73 245.8 0.1 7.2e-73 244.9 0.1 1.4 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 EJS44749.1 - 2.7e-64 216.3 0.4 5.5e-64 215.3 0.4 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5 PF05185.16 EJS44749.1 - 1.3e-58 197.7 0.0 2.1e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CKS PF01111.19 EJS44750.1 - 4.5e-35 119.7 0.2 7.4e-35 119.1 0.2 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit SUIM_assoc PF16619.5 EJS44750.1 - 0.07 13.2 18.2 2.9 8.0 18.2 2.2 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 EJS44750.1 - 0.76 8.5 4.1 0.94 8.2 4.1 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 EJS44750.1 - 0.91 9.1 23.1 1.3 8.6 23.1 1.2 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 EJS44750.1 - 1.3 10.1 7.1 2.2 9.3 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 EJS44750.1 - 2.1 8.3 18.2 2.4 8.1 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3464 PF11947.8 EJS44750.1 - 2.2 8.0 8.0 3.2 7.5 8.0 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 PI3_PI4_kinase PF00454.27 EJS44751.1 - 1.1e-59 202.3 0.4 7.5e-59 199.6 0.1 2.6 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 EJS44751.1 - 5.2e-28 97.0 0.1 4e-27 94.1 0.1 2.8 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 EJS44751.1 - 2.3e-14 52.9 0.1 4.6e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EJS44751.1 - 2.3e-06 27.1 8.1 6e-06 25.7 5.6 2.7 2 0 0 2 2 2 1 FAT domain TPR_19 PF14559.6 EJS44751.1 - 0.062 13.8 0.0 0.24 11.9 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Lyase_8_N PF08124.11 EJS44751.1 - 0.13 11.2 6.2 3.9 6.3 0.1 4.2 4 0 0 4 4 4 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Haem_degrading PF03928.14 EJS44752.1 - 2.9e-27 95.1 0.0 3.7e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading RasGAP PF00616.19 EJS44753.1 - 2.4e-22 79.7 0.8 2e-10 40.7 0.1 3.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase Bmt2 PF11968.8 EJS44754.1 - 2.3e-75 253.2 0.0 3.1e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EJS44754.1 - 0.00013 21.9 0.1 0.0011 18.9 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EJS44754.1 - 0.015 16.0 0.0 0.038 14.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EJS44754.1 - 0.015 15.9 0.0 0.039 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 EJS44754.1 - 0.052 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase CheR PF01739.18 EJS44754.1 - 0.099 12.1 0.2 0.62 9.5 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain NodS PF05401.11 EJS44754.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) eRF1_2 PF03464.15 EJS44755.1 - 8.1e-46 155.6 0.0 1.6e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EJS44755.1 - 3.5e-38 130.6 0.2 8e-38 129.4 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EJS44755.1 - 4.8e-19 68.6 0.0 7.9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 EJS44755.1 - 2.6e-10 40.7 0.0 4.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 EJS44755.1 - 1.8e-08 34.8 0.0 2.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 ADH_N PF08240.12 EJS44756.1 - 1.5e-29 102.1 0.7 1.5e-29 102.1 0.7 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EJS44756.1 - 3.8e-26 91.6 0.4 5.6e-26 91.1 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJS44756.1 - 3e-05 25.1 0.0 4.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EJS44756.1 - 0.012 15.2 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EJS44756.1 - 0.043 13.1 0.1 0.065 12.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EJS44756.1 - 0.096 12.1 0.3 0.16 11.4 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NqrM PF04400.13 EJS44756.1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.2 2 0 0 2 2 2 0 (Na+)-NQR maturation NqrM Ribosomal_S9 PF00380.19 EJS44757.1 - 7.4e-42 142.7 0.2 1.2e-41 142.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2277 PF10041.9 EJS44757.1 - 0.16 12.3 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) PQ-loop PF04193.14 EJS44758.1 - 3e-40 135.8 11.2 9.3e-23 79.8 2.9 3.2 5 0 0 5 5 5 2 PQ loop repeat Steroid_dh PF02544.16 EJS44758.1 - 0.16 11.9 1.6 0.3 11.0 0.2 2.1 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Aldo_ket_red PF00248.21 EJS44759.1 - 1e-35 123.4 0.0 4.1e-34 118.1 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Suc_Fer-like PF06999.12 EJS44760.1 - 1.2e-46 159.1 0.0 1.4e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like MFAP1 PF06991.11 EJS44761.1 - 2.6e-07 30.7 22.2 2.6e-07 30.7 22.2 2.5 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing APC_u15 PF16636.5 EJS44761.1 - 0.022 15.2 8.0 0.022 15.2 8.0 3.9 2 2 2 4 4 4 0 Unstructured region on APC between APC_crr regions 5 and 6 RNA_pol_Rpb5_C PF01191.19 EJS44762.1 - 1.2e-31 108.4 0.3 2.6e-31 107.3 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EJS44762.1 - 1.8e-29 102.2 0.2 3.1e-29 101.4 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EJS44762.1 - 0.024 14.6 0.0 0.08 13.0 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease Sof1 PF04158.14 EJS44762.1 - 0.063 13.5 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Sof1-like domain SH3_2 PF07653.17 EJS44762.1 - 0.16 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Gly_transf_sug PF04488.15 EJS44764.1 - 1.3e-21 77.0 0.0 3.8e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF2401 PF10287.9 EJS44765.1 - 4.8e-94 314.2 1.8 4.8e-94 314.2 1.8 1.8 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EJS44765.1 - 4.8e-27 94.2 0.2 1.9e-26 92.3 0.0 2.1 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) GREB1 PF15782.5 EJS44765.1 - 2 5.4 8.3 2.3 5.2 8.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NUDE_C PF04880.13 EJS44765.1 - 2.8 8.4 12.0 4.4 7.7 12.0 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Macoilin PF09726.9 EJS44765.1 - 4.4 5.7 12.7 5.8 5.3 12.7 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EJS44765.1 - 8.1 5.2 9.1 10 4.9 9.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAMP4 PF06624.12 EJS44766.1 - 9.6e-12 44.8 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Arf PF00025.21 EJS44767.1 - 8.8e-77 256.5 0.1 1e-76 256.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EJS44767.1 - 9.6e-16 58.1 0.0 1.3e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EJS44767.1 - 2.3e-11 43.5 0.0 2.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EJS44767.1 - 4e-11 42.8 0.0 4.5e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EJS44767.1 - 2.8e-10 39.9 0.3 3.8e-06 26.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EJS44767.1 - 6.1e-10 38.8 0.0 7.7e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EJS44767.1 - 7.8e-05 22.7 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJS44767.1 - 0.00017 21.2 0.2 0.0014 18.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EJS44767.1 - 0.00056 20.4 0.4 0.0022 18.5 0.4 1.7 1 1 0 1 1 1 1 ABC transporter MeaB PF03308.16 EJS44767.1 - 0.0032 16.5 0.6 0.17 10.9 0.2 2.7 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EJS44767.1 - 0.042 14.4 0.1 0.096 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EJS44767.1 - 0.097 12.3 1.0 9 5.8 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EJS44767.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EJS44767.1 - 0.15 11.7 0.4 0.69 9.5 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF5423 PF17461.2 EJS44768.1 - 0.049 12.5 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Rpp20 PF12328.8 EJS44769.1 - 1.5e-28 99.4 4.0 3.5e-26 91.8 4.0 2.2 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EJS44769.1 - 1e-10 41.2 0.3 1.8e-10 40.5 0.3 1.3 1 0 0 1 1 1 1 Alba Pex24p PF06398.11 EJS44770.1 - 1.8e-62 211.5 15.7 2e-62 211.3 15.7 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HSP70 PF00012.20 EJS44771.1 - 2e-188 627.4 0.2 2e-188 627.4 0.2 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJS44771.1 - 1.4e-11 43.8 0.1 4.4e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EJS44771.1 - 0.00027 21.3 0.4 0.0093 16.4 0.0 2.9 2 1 0 2 2 2 1 Cell division protein FtsA CT_C_D PF02682.16 EJS44771.1 - 0.041 13.6 0.3 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D NLE PF08154.12 EJS44771.1 - 0.091 13.3 0.1 0.35 11.4 0.1 2.0 1 0 0 1 1 1 0 NLE (NUC135) domain FGGY_C PF02782.16 EJS44771.1 - 0.11 12.2 0.1 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain NPL4 PF05021.15 EJS44772.1 - 3.1e-141 470.1 0.2 4.1e-141 469.7 0.2 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EJS44772.1 - 1.7e-70 235.8 2.0 2.6e-70 235.2 2.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EJS44772.1 - 1.3e-06 28.7 0.1 5.3e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 EJS44773.1 - 9.5e-70 233.8 1.2 1.1e-69 233.6 1.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 GYF PF02213.16 EJS44774.1 - 1.5e-14 53.4 0.0 3.9e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 GYF domain UMP1 PF05348.11 EJS44775.1 - 1.7e-42 144.4 0.2 2e-42 144.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 WD40 PF00400.32 EJS44776.1 - 4.3e-24 84.3 11.4 1.1e-06 29.2 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44776.1 - 6e-19 68.1 0.0 0.0026 18.0 0.0 5.7 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EJS44776.1 - 8.9e-06 24.6 0.1 0.043 12.5 0.1 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EJS44776.1 - 3.4e-05 22.6 0.0 0.0072 14.9 0.0 2.7 2 1 1 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.12 EJS44776.1 - 0.0014 18.5 0.0 0.73 9.8 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EJS44776.1 - 0.0041 16.1 0.3 1.6 7.6 0.0 3.7 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EJS44776.1 - 0.0093 15.3 0.9 1.1 8.5 0.1 2.7 2 1 0 2 2 2 2 WD40-like domain DPPIV_N PF00930.21 EJS44776.1 - 0.012 14.4 0.0 0.63 8.7 0.0 2.4 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_1 PF00561.20 EJS44777.1 - 1.6e-35 123.0 0.0 2.7e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EJS44777.1 - 4.7e-13 49.0 0.0 8.8e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EJS44777.1 - 0.00096 18.7 0.0 0.063 12.8 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EJS44777.1 - 0.0014 19.3 0.0 0.0021 18.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family ORC3_N PF07034.11 EJS44777.1 - 0.0035 16.5 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Palm_thioest PF02089.15 EJS44777.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Dynamin_N PF00350.23 EJS44778.1 - 3.3e-14 53.3 2.1 3.7e-14 53.1 0.3 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EJS44778.1 - 1.1e-09 38.3 0.1 8.7e-09 35.5 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EJS44778.1 - 4.4e-08 32.9 0.4 3.2e-05 23.6 0.3 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EJS44778.1 - 0.013 15.3 0.2 8.9 6.1 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EJS44778.1 - 0.33 10.5 2.9 0.75 9.4 0.3 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Gemini_AL1 PF00799.20 EJS44778.1 - 0.52 10.7 4.0 0.35 11.3 0.8 2.3 2 0 0 2 2 2 0 Geminivirus Rep catalytic domain TTL PF03133.15 EJS44779.1 - 2.5e-93 312.4 4.5 3.6e-93 311.9 4.5 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EJS44779.1 - 1.3e-43 149.0 0.0 2.1e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EJS44779.1 - 0.00019 20.8 0.0 0.0065 15.8 0.0 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp Nro1 PF12753.7 EJS44779.1 - 0.028 13.4 3.2 0.051 12.5 3.2 1.4 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Herpes_BLLF1 PF05109.13 EJS44779.1 - 0.047 11.7 0.1 0.067 11.2 0.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) ATPgrasp_ST PF14397.6 EJS44779.1 - 0.1 11.8 0.0 3.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RXT2_N PF08595.11 EJS44780.1 - 3.6e-43 147.3 0.8 3.6e-43 147.3 0.8 2.7 3 1 0 3 3 3 1 RXT2-like, N-terminal IclR PF01614.18 EJS44780.1 - 0.085 12.7 0.3 6.8 6.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial transcriptional regulator 4HBT_2 PF13279.6 EJS44781.1 - 1.7e-08 35.0 0.0 2.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.25 EJS44782.1 - 2.3e-25 89.5 0.0 6e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44782.1 - 3.6e-13 49.4 0.0 6.9e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 EJS44782.1 - 8.4e-06 25.6 1.0 3.1 8.3 0.0 6.1 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 EJS44782.1 - 0.00041 20.4 7.6 0.061 13.4 0.3 3.6 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 EJS44782.1 - 0.0059 16.0 0.1 0.029 13.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like WD40 PF00400.32 EJS44782.1 - 0.014 16.3 1.1 0.62 11.0 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat HEAT_2 PF13646.6 EJS44782.1 - 0.018 15.4 0.0 0.13 12.7 0.0 2.4 3 0 0 3 3 3 0 HEAT repeats RTP1_C1 PF10363.9 EJS44782.1 - 0.15 12.3 2.8 1.8 8.8 0.5 2.9 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 ANAPC4_WD40 PF12894.7 EJS44782.1 - 0.16 12.3 0.0 16 5.8 0.0 2.7 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ERCC4 PF02732.15 EJS44783.1 - 2.5e-19 70.0 3.3 2.5e-19 70.0 3.3 1.9 1 1 1 2 2 2 1 ERCC4 domain RSRP PF17069.5 EJS44783.1 - 0.24 10.9 7.1 0.38 10.3 4.1 2.3 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 Fes1 PF08609.10 EJS44784.1 - 3e-23 82.5 0.5 1.8e-22 80.0 0.1 2.4 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 IBN_N PF03810.19 EJS44784.1 - 0.00028 20.8 0.5 0.24 11.3 0.1 2.9 1 1 1 2 2 2 2 Importin-beta N-terminal domain HEAT_2 PF13646.6 EJS44784.1 - 0.00046 20.5 0.1 0.0039 17.6 0.0 2.5 2 1 0 2 2 2 1 HEAT repeats TAF1_subA PF14929.6 EJS44784.1 - 0.026 14.0 0.1 0.044 13.2 0.1 1.5 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A HEAT_EZ PF13513.6 EJS44784.1 - 0.043 14.3 0.5 0.54 10.8 0.5 2.6 1 1 0 1 1 1 0 HEAT-like repeat Atx10homo_assoc PF09759.9 EJS44784.1 - 0.048 13.7 0.9 1.6 8.8 0.0 2.6 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.8 EJS44784.1 - 0.084 13.0 1.8 0.31 11.1 0.4 2.5 2 1 2 4 4 4 0 V-ATPase subunit H Exo84_C PF16528.5 EJS44785.1 - 1.3e-73 247.2 3.2 1.3e-73 247.2 3.2 2.1 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EJS44785.1 - 3.2e-08 33.5 2.1 3.2e-08 33.5 2.1 2.4 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.11 EJS44785.1 - 0.049 13.7 8.2 0.032 14.3 2.6 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Fzo_mitofusin PF04799.13 EJS44785.1 - 0.82 9.2 7.7 0.17 11.4 2.7 2.3 2 0 0 2 2 2 0 fzo-like conserved region Phage_GP20 PF06810.11 EJS44785.1 - 0.83 9.5 8.5 0.58 9.9 4.3 2.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 WD40 PF00400.32 EJS44786.1 - 3.3e-20 72.0 16.1 1.6e-06 28.7 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EJS44786.1 - 1.8e-13 50.6 7.5 0.0038 17.5 0.1 6.8 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EJS44786.1 - 1.3e-06 28.1 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 EJS44786.1 - 2.9e-06 26.8 0.3 0.068 12.5 0.1 3.3 1 1 2 3 3 3 3 WD40-like domain RAB3GAP2_N PF14655.6 EJS44786.1 - 0.0039 16.5 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 EJS44786.1 - 0.062 12.3 0.0 9.4 5.1 0.0 3.2 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mito_carr PF00153.27 EJS44787.1 - 1.1e-60 201.6 1.6 6.7e-22 77.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein P5CR_dimer PF14748.6 EJS44787.1 - 0.13 12.5 0.2 3.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation Vac_ImportDeg PF09783.9 EJS44788.1 - 6e-58 195.2 1.6 9.8e-58 194.5 1.6 1.3 1 0 0 1 1 1 1 Vacuolar import and degradation protein Pho88 PF10032.9 EJS44789.1 - 1.3e-82 275.5 0.6 1.4e-82 275.3 0.6 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) CENP-L PF13092.6 EJS44790.1 - 0.0019 18.4 0.0 0.0048 17.1 0.0 1.7 1 1 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 EF-hand_1 PF00036.32 EJS44791.1 - 6.7e-31 103.5 4.1 1.4e-08 33.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EJS44791.1 - 5.9e-27 93.9 0.3 2.7e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EJS44791.1 - 2.5e-26 89.3 3.7 5.5e-08 32.1 0.0 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EJS44791.1 - 5.2e-18 63.7 4.2 4.9e-07 29.0 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EJS44791.1 - 2.5e-16 59.2 5.3 2.8e-08 33.5 0.1 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EJS44791.1 - 5.7e-13 49.0 0.0 5.6e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EJS44791.1 - 1.3e-06 28.7 0.1 0.00093 19.5 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 EJS44791.1 - 1.9e-05 24.9 0.1 0.25 11.7 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 EJS44791.1 - 5.1e-05 23.2 0.0 0.015 15.3 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 EJS44791.1 - 0.0013 18.8 0.7 0.5 10.6 0.2 2.5 1 1 1 2 2 2 2 Dockerin type I domain Caleosin PF05042.13 EJS44791.1 - 0.002 18.1 0.0 1.2 9.0 0.0 3.0 1 1 2 3 3 3 1 Caleosin related protein EF-hand_4 PF12763.7 EJS44791.1 - 0.0031 17.5 0.4 0.0085 16.0 0.1 1.7 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 EJS44791.1 - 0.0031 17.5 0.1 0.066 13.2 0.0 2.2 2 1 0 2 2 2 1 Tellurite resistance protein TerB DUF853 PF05872.12 EJS44791.1 - 0.0044 15.7 0.3 0.11 11.1 0.1 2.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) SurA_N_3 PF13624.6 EJS44791.1 - 0.019 14.8 0.5 0.62 9.8 0.3 2.0 1 1 1 2 2 2 0 SurA N-terminal domain GPHH PF16905.5 EJS44791.1 - 0.075 12.8 0.0 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated RNA_pol_Rpb4 PF03874.16 EJS44791.1 - 0.088 13.1 1.0 1.7 9.0 0.1 2.5 2 1 0 2 2 2 0 RNA polymerase Rpb4 Glycos_trans_3N PF02885.17 EJS44791.1 - 0.093 12.6 2.9 3.2 7.7 0.1 3.4 1 1 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Glycos_transf_1 PF00534.20 EJS44792.1 - 3.8e-12 46.1 0.0 6.9e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EJS44792.1 - 9.9e-06 26.0 0.0 2.2e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EJS44792.1 - 2.4e-05 24.4 0.0 6.1e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EJS44792.1 - 0.0023 18.3 0.0 0.0046 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EJS44792.1 - 0.031 14.7 0.0 0.042 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain SNF2_N PF00176.23 EJS44793.1 - 4.5e-54 183.5 0.1 1.5e-53 181.7 0.1 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJS44793.1 - 1.7e-14 54.1 0.0 8.3e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EJS44793.1 - 2.6e-09 37.1 0.0 5.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EJS44793.1 - 6.8e-09 35.9 0.0 1.9e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EJS44793.1 - 7.1e-08 32.2 11.3 7.1e-08 32.2 11.3 2.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EJS44793.1 - 0.00044 20.0 9.1 0.00044 20.0 9.1 2.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EJS44793.1 - 0.00054 19.9 5.7 0.00054 19.9 5.7 2.2 2 1 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EJS44793.1 - 0.0022 17.8 8.3 0.0022 17.8 8.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EJS44793.1 - 0.0032 17.8 9.5 0.0032 17.8 9.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 EJS44793.1 - 0.0051 16.9 9.8 0.0051 16.9 9.8 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING MH2 PF03166.14 EJS44793.1 - 0.013 15.7 0.0 0.045 14.0 0.0 1.9 1 1 1 2 2 2 0 MH2 domain zf-Nse PF11789.8 EJS44793.1 - 0.16 11.8 6.5 0.44 10.4 6.5 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS91 PF14319.6 EJS44793.1 - 1.1 9.4 14.5 0.062 13.3 3.0 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_10 PF16685.5 EJS44793.1 - 5.4 7.2 12.6 0.035 14.3 3.3 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 NAD_binding_4 PF07993.12 EJS44794.1 - 2.5e-71 239.9 0.0 4.2e-71 239.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EJS44794.1 - 2.7e-67 227.2 0.0 3.6e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EJS44794.1 - 1.1e-14 54.5 0.0 2.3e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EJS44794.1 - 9.1e-09 35.1 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EJS44794.1 - 1.4e-05 25.9 0.0 5e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 EJS44794.1 - 4e-05 22.8 0.0 0.00013 21.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.20 EJS44794.1 - 0.00062 18.6 3.4 0.0045 15.7 1.6 2.1 2 0 0 2 2 2 1 Condensation domain GDP_Man_Dehyd PF16363.5 EJS44794.1 - 0.0021 17.5 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Transketolase_N PF00456.21 EJS44795.1 - 1.4e-159 530.5 0.0 1.8e-159 530.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EJS44795.1 - 3.6e-49 166.8 0.0 6e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EJS44795.1 - 5.5e-12 45.7 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EJS44795.1 - 4.5e-05 22.8 0.0 0.00018 20.8 0.0 1.8 1 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EJS44795.1 - 0.0012 18.7 0.2 1.9 8.2 0.1 2.5 1 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EJS44795.1 - 0.012 14.6 0.0 0.031 13.2 0.0 1.6 2 0 0 2 2 2 0 Dehydrogenase E1 component ThiP_synth PF10120.9 EJS44795.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Thiamine-phosphate synthase Lant_dehydr_C PF14028.6 EJS44795.1 - 0.19 11.2 0.1 0.29 10.6 0.1 1.2 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term FtsJ PF01728.19 EJS44796.1 - 9.6e-66 221.2 0.0 1.2e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF268 PF03269.14 EJS44796.1 - 0.2 11.5 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 AP3D1 PF06375.11 EJS44797.1 - 0.72 10.1 8.3 0.74 10.0 3.8 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 zf-C2H2 PF00096.26 EJS44798.1 - 0.0007 19.9 20.0 0.014 15.8 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EJS44798.1 - 0.0018 18.9 15.4 0.19 12.6 2.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EJS44798.1 - 0.0022 18.4 2.5 0.0022 18.4 2.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 EJS44798.1 - 1.4 9.4 8.3 0.3 11.5 1.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type AA_permease PF00324.21 EJS44799.1 - 5.5e-140 467.1 37.9 6.9e-140 466.8 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS44799.1 - 1.8e-34 119.3 34.7 2.4e-34 118.9 34.7 1.1 1 0 0 1 1 1 1 Amino acid permease Synaptobrevin PF00957.21 EJS44799.1 - 0.36 10.7 0.0 0.36 10.7 0.0 3.5 5 0 0 5 5 5 0 Synaptobrevin AA_permease PF00324.21 EJS44800.1 - 7.5e-129 430.4 38.3 8.6e-129 430.2 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EJS44800.1 - 1.5e-40 139.4 36.9 1.9e-40 139.0 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 EJS44800.1 - 0.037 14.5 0.8 0.11 13.1 0.8 1.7 1 0 0 1 1 1 0 Pet100 ROK PF00480.20 EJS44800.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 ROK family PB1-F2 PF11986.8 EJS44800.1 - 1.3 9.3 3.6 1.3 9.3 0.0 2.6 3 0 0 3 3 3 0 Influenza A Proapoptotic protein Alg14 PF08660.11 EJS44801.1 - 1.1e-55 188.3 0.1 1.6e-55 187.8 0.1 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Rad33 PF08730.10 EJS44801.1 - 0.061 13.3 0.2 0.085 12.8 0.2 1.2 1 0 0 1 1 1 0 Rad33 HSP20 PF00011.21 EJS44803.1 - 4e-26 91.1 2.8 5.3e-26 90.7 2.8 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EJS44803.1 - 2e-06 27.2 0.0 3.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Ntox50 PF15542.6 EJS44803.1 - 0.028 15.2 0.8 0.064 14.1 0.8 1.7 2 0 0 2 2 2 0 Bacterial toxin 50 Pih1_fungal_CS PF18482.1 EJS44803.1 - 0.031 14.8 1.3 0.061 13.9 0.8 1.9 1 1 0 1 1 1 0 Fungal Pih1 CS domain Peptidase_M28 PF04389.17 EJS44804.1 - 4.8e-41 140.6 0.0 8e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EJS44804.1 - 0.00073 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EJS44804.1 - 0.007 15.4 0.0 0.03 13.3 0.0 1.8 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase SLM4 PF16818.5 EJS44805.1 - 1.1e-62 210.8 2.1 1.2e-62 210.6 2.1 1.0 1 0 0 1 1 1 1 Protein SLM4 PCI PF01399.27 EJS44806.1 - 1.4e-06 28.7 7.9 2.4e-06 28.0 0.3 4.0 3 1 1 4 4 4 1 PCI domain MIP-T3 PF10243.9 EJS44806.1 - 2.8 8.0 8.2 3.4 7.7 0.9 3.0 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 CH-like domain AAA PF00004.29 EJS44807.1 - 3.2e-51 173.2 0.0 2.3e-38 131.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EJS44807.1 - 3e-10 39.8 0.1 8e-10 38.4 0.1 1.8 1 1 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 EJS44807.1 - 7.2e-10 38.5 0.8 3e-09 36.5 0.1 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 EJS44807.1 - 1.9e-09 37.9 0.4 0.00042 20.6 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EJS44807.1 - 2.2e-09 37.9 0.1 0.00096 19.6 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain CDC48_N PF02359.18 EJS44807.1 - 5.4e-07 29.7 0.0 2.1e-06 27.8 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.6 EJS44807.1 - 7.3e-07 29.4 0.0 0.0068 16.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EJS44807.1 - 8.5e-07 28.5 0.1 0.035 13.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 EJS44807.1 - 1e-06 28.8 0.2 0.0026 17.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EJS44807.1 - 1.5e-06 27.7 0.1 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EJS44807.1 - 9.1e-06 25.5 0.1 0.091 12.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 EJS44807.1 - 1.1e-05 25.5 2.8 0.023 14.6 0.1 3.7 4 0 0 4 4 3 2 NACHT domain RuvB_N PF05496.12 EJS44807.1 - 2.1e-05 24.3 0.6 0.07 12.9 0.1 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EJS44807.1 - 2.2e-05 24.8 0.1 0.13 12.7 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.6 EJS44807.1 - 2.3e-05 25.0 0.0 0.48 11.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain PhoH PF02562.16 EJS44807.1 - 3.7e-05 23.3 0.0 0.042 13.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.22 EJS44807.1 - 3.8e-05 23.0 0.1 0.024 13.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_2 PF07724.14 EJS44807.1 - 4.7e-05 23.6 0.0 0.0018 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 EJS44807.1 - 6e-05 23.0 0.0 0.55 10.2 0.0 3.1 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EJS44807.1 - 0.00029 20.6 0.0 0.78 9.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EJS44807.1 - 0.00031 21.3 0.7 0.035 14.6 0.1 2.5 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 EJS44807.1 - 0.00032 20.3 0.1 0.07 12.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 EJS44807.1 - 0.00038 20.2 0.0 0.26 11.0 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF2075 PF09848.9 EJS44807.1 - 0.00045 19.6 0.0 0.63 9.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EJS44807.1 - 0.00059 19.6 0.1 0.87 9.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EJS44807.1 - 0.00085 19.4 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 EJS44807.1 - 0.0016 18.4 0.3 0.98 9.3 0.0 3.2 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EJS44807.1 - 0.0018 18.1 0.1 0.56 10.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EJS44807.1 - 0.0019 18.2 0.0 3.1 7.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EJS44807.1 - 0.0022 17.4 0.4 0.28 10.5 0.1 2.6 2 0 0 2 2 2 1 KaiC TniB PF05621.11 EJS44807.1 - 0.0025 17.2 0.1 3.6 6.9 0.0 3.2 2 1 0 2 2 2 1 Bacterial TniB protein AAA_23 PF13476.6 EJS44807.1 - 0.0047 17.5 2.0 6.2 7.3 0.2 3.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EJS44807.1 - 0.008 15.8 0.9 4.4 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EJS44807.1 - 0.01 16.2 0.1 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 EJS44807.1 - 0.017 14.5 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase Rad17 PF03215.15 EJS44807.1 - 0.019 14.9 0.1 5.3 6.9 0.0 2.8 2 1 0 2 2 2 0 Rad17 P-loop domain AAA_17 PF13207.6 EJS44807.1 - 0.02 15.3 0.1 4.7 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EJS44807.1 - 0.023 14.5 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 EJS44807.1 - 0.026 14.8 0.0 5.6 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EJS44807.1 - 0.036 13.9 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EJS44807.1 - 0.038 13.1 0.0 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 EJS44807.1 - 0.055 13.3 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein T2SSE PF00437.20 EJS44807.1 - 0.062 12.4 0.0 8.3 5.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 EJS44807.1 - 0.064 13.0 0.1 5.4 6.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain TEA PF01285.18 EJS44808.1 - 1.4e-24 86.0 0.2 3.1e-24 84.8 0.2 1.6 1 0 0 1 1 1 1 TEA/ATTS domain MCM6_C PF18263.1 EJS44808.1 - 0.0068 16.6 0.5 0.0068 16.6 0.5 1.9 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain FTHFS PF01268.19 EJS44809.1 - 3.4e-252 837.6 0.8 4.5e-252 837.2 0.8 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EJS44809.1 - 7.4e-70 233.4 0.5 7.4e-70 233.4 0.5 2.6 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EJS44809.1 - 2.6e-36 124.4 1.0 5.9e-36 123.3 0.5 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EJS44809.1 - 0.019 13.9 0.4 0.019 13.9 0.4 1.9 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Mito_carr PF00153.27 EJS44810.1 - 5.4e-68 225.0 7.8 1.4e-24 85.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 EJS44810.1 - 0.11 11.7 0.1 0.52 9.5 0.1 1.8 2 0 0 2 2 2 0 Fuseless Spt5-NGN PF03439.13 EJS44811.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Anoctamin PF04547.12 EJS44812.1 - 1.7e-40 139.2 25.2 2.9e-40 138.4 25.2 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel DNA_pol3_delta2 PF13177.6 EJS44813.1 - 2e-10 40.7 0.3 1.9e-09 37.5 0.3 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EJS44813.1 - 1.8e-08 34.9 0.0 5.1e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EJS44813.1 - 0.00028 20.7 2.4 0.00033 20.5 0.4 2.2 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 EJS44813.1 - 0.0057 17.0 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EJS44813.1 - 0.0079 16.1 0.0 0.017 15.1 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain Rep_fac_C PF08542.11 EJS44813.1 - 0.011 16.2 0.7 0.058 13.8 0.1 2.4 2 1 0 2 2 2 0 Replication factor C C-terminal domain AAA_assoc_2 PF16193.5 EJS44813.1 - 0.019 15.3 0.1 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA C-terminal domain RuvB_N PF05496.12 EJS44813.1 - 0.03 14.0 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EJS44813.1 - 0.052 13.8 0.9 0.32 11.3 0.3 2.6 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EJS44813.1 - 0.11 12.5 0.2 0.4 10.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EJS44813.1 - 0.19 11.5 0.2 0.57 9.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain PCNA_C PF02747.15 EJS44814.1 - 3.3e-55 185.7 0.1 8.9e-55 184.3 0.1 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 EJS44814.1 - 6.5e-55 184.3 1.3 6.5e-55 184.3 1.3 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 EJS44814.1 - 0.00058 19.0 0.7 0.0042 16.2 0.7 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EJS44814.1 - 0.0019 17.7 0.1 0.0024 17.4 0.1 1.2 1 0 0 1 1 1 1 Rad9 Histone PF00125.24 EJS44814.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 HMG_box PF00505.19 EJS44815.1 - 7.8e-24 83.9 0.2 1.3e-23 83.2 0.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EJS44815.1 - 2.2e-17 63.4 0.2 3.4e-17 62.8 0.2 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 EJS44815.1 - 0.023 14.6 0.2 0.023 14.6 0.2 1.6 2 0 0 2 2 2 0 HMG (high mobility group) box 5 CHDNT PF08073.12 EJS44815.1 - 0.023 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain PrmA PF06325.13 EJS44816.1 - 3.2e-12 46.5 0.0 1.6e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EJS44816.1 - 9.8e-12 45.4 0.0 2.5e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EJS44816.1 - 5.2e-09 36.1 0.0 1.2e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EJS44816.1 - 1.1e-08 35.6 0.0 3.3e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EJS44816.1 - 3.7e-07 30.1 0.0 6.1e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EJS44816.1 - 9.6e-06 24.7 0.1 1.4e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EJS44816.1 - 4.2e-05 23.0 0.0 5.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EJS44816.1 - 4.4e-05 23.1 0.0 8.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EJS44816.1 - 0.00014 21.8 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EJS44816.1 - 0.00039 20.2 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 EJS44816.1 - 0.00046 19.5 0.0 0.00074 18.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 EJS44816.1 - 0.00047 20.9 0.0 0.0012 19.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EJS44816.1 - 0.0046 17.1 0.0 0.013 15.6 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EJS44816.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EJS44816.1 - 0.017 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 EJS44816.1 - 0.063 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DOT1 PF08123.13 EJS44816.1 - 0.082 12.4 0.2 0.2 11.2 0.1 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 Cons_hypoth95 PF03602.15 EJS44816.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRMT5 PF05185.16 EJS44816.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PNP_phzG_C PF10590.9 EJS44817.1 - 4.2e-21 74.7 2.8 1e-20 73.5 2.8 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EJS44817.1 - 1.9e-14 53.6 0.0 2.8e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EJS44817.1 - 0.015 15.9 0.1 0.026 15.1 0.1 1.5 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase KdpC PF02669.15 EJS44817.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain CSG2 PF16965.5 EJS44818.1 - 1.5e-182 606.9 10.3 1.7e-182 606.8 10.3 1.0 1 0 0 1 1 1 1 Ceramide synthase regulator Chitin_synth_1 PF01644.17 EJS44819.1 - 2.9e-69 232.2 0.3 4.5e-69 231.6 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 EJS44819.1 - 4e-23 81.8 5.2 1.2e-18 67.1 0.0 3.0 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 EJS44819.1 - 1.2e-21 76.4 0.1 3.6e-21 74.9 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.6 EJS44819.1 - 9.2e-08 32.3 0.0 4e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EJS44819.1 - 2e-07 31.1 1.1 2e-07 31.1 1.1 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Ant_C PF05586.11 EJS44819.1 - 0.15 12.7 1.0 1.5 9.4 1.0 2.4 1 1 0 1 1 1 0 Anthrax receptor C-terminus region ATP-synt PF00231.19 EJS44820.1 - 1.6e-73 247.9 4.8 1.8e-73 247.7 4.8 1.0 1 0 0 1 1 1 1 ATP synthase MecA_N PF05223.11 EJS44820.1 - 0.0091 16.3 3.3 0.022 15.0 3.3 1.7 1 0 0 1 1 1 1 NTF2-like N-terminal transpeptidase domain Fig1 PF12351.8 EJS44821.1 - 9.2e-59 198.5 5.7 9.2e-59 198.5 5.7 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EJS44821.1 - 0.0002 21.1 13.9 0.00028 20.6 13.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family OST3_OST6 PF04756.13 EJS44821.1 - 1.8 7.9 10.7 0.03 13.7 2.5 2.0 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family PIG-P PF08510.12 EJS44821.1 - 3.4 7.6 8.3 1.6 8.6 4.0 2.2 2 0 0 2 2 2 0 PIG-P AMP-binding PF00501.28 EJS44822.1 - 4.8e-55 186.9 0.0 6e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJS44822.1 - 0.0006 20.7 0.0 0.0011 19.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.26 EJS44823.1 - 1.2e-23 83.5 0.0 2.1e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EJS44823.1 - 5.1e-14 53.5 0.0 1.7e-13 51.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EJS44823.1 - 2.8e-08 33.6 0.0 7.8e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain SH3_12 PF18129.1 EJS44823.1 - 0.1 12.7 0.0 0.34 11.0 0.0 1.9 2 0 0 2 2 2 0 Xrn1 SH3-like domain FMP23 PF17315.2 EJS44824.1 - 7.6e-67 224.2 3.2 9.3e-67 223.9 3.2 1.1 1 0 0 1 1 1 1 Found in mitochondrial proteome 5_3_exonuc_N PF02739.16 EJS44825.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain SGL PF08450.12 EJS44826.1 - 4.4e-49 167.3 0.0 5.7e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EJS44826.1 - 0.00033 20.8 0.0 0.85 9.9 0.0 2.4 2 0 0 2 2 2 2 Arylesterase Bac_rhodopsin PF01036.18 EJS44827.1 - 9.2e-41 139.9 18.0 1.2e-40 139.4 18.0 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PIRT PF15099.6 EJS44827.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.4 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Phage_holin_1 PF04531.13 EJS44827.1 - 0.18 12.3 1.0 0.38 11.3 0.2 2.0 2 0 0 2 2 2 0 Bacteriophage holin SR-25 PF10500.9 EJS44827.1 - 0.48 10.0 18.2 0.61 9.6 18.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GpcrRhopsn4 PF10192.9 EJS44827.1 - 1.3 8.4 18.5 0.17 11.2 6.7 2.2 1 1 1 2 2 2 0 Rhodopsin-like GPCR transmembrane domain Med19 PF10278.9 EJS44827.1 - 2.3 8.1 14.7 3.5 7.5 14.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 AP3D1 PF06375.11 EJS44827.1 - 3.5 7.8 14.6 4.8 7.4 14.6 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF3969 PF13108.6 EJS44828.1 - 0.081 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) Wtap PF17098.5 EJS44830.1 - 4.5e-08 33.2 19.2 3.1e-07 30.5 18.6 2.2 1 1 0 1 1 1 1 WTAP/Mum2p family DUF4407 PF14362.6 EJS44830.1 - 1.6 8.0 6.7 3.8 6.8 6.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) EMP24_GP25L PF01105.24 EJS44830.1 - 3.5 7.5 8.6 0.31 11.0 1.7 2.5 2 1 0 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.6 EJS44830.1 - 5.4 7.5 8.3 20 5.7 0.1 3.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF641 PF04859.12 EJS44830.1 - 5.7 7.3 17.0 0.39 11.1 1.0 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) UCH PF00443.29 EJS44831.1 - 1.7e-43 149.0 0.3 1.7e-43 149.0 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EJS44831.1 - 1.2e-18 67.2 8.9 1.2e-18 67.2 8.9 3.1 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EJS44831.1 - 1.2e-15 57.9 0.7 1.2e-15 57.9 0.7 3.3 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EJS44831.1 - 3.7e-15 55.5 0.0 6.9e-09 35.4 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 EJS44831.1 - 1e-09 38.0 5.0 1e-09 38.0 5.0 3.0 2 1 0 2 2 2 1 Variant UBP zinc finger LMBR1 PF04791.16 EJS44831.1 - 0.04 12.8 1.4 0.051 12.5 1.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TFIIS_C PF01096.18 EJS44831.1 - 7.6 6.5 7.5 21 5.1 0.1 3.9 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Pkinase PF00069.25 EJS44833.1 - 4.1e-35 121.4 0.1 4.1e-35 121.4 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44833.1 - 1e-22 80.7 0.0 1e-22 80.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EJS44833.1 - 0.021 14.7 0.0 2.4 8.0 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3811 PF11656.8 EJS44833.1 - 0.98 9.9 8.6 0.84 10.1 0.2 3.5 3 0 0 3 3 3 0 YjbD family (DUF3811) ORC2 PF04084.14 EJS44834.1 - 3.3e-109 364.8 0.5 4.5e-109 364.4 0.5 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.19 EJS44834.1 - 0.1 12.6 3.8 0.35 10.9 3.8 2.0 1 0 0 1 1 1 0 AT hook motif adh_short PF00106.25 EJS44835.1 - 9.4e-26 90.5 0.0 1.2e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EJS44835.1 - 8.6e-25 87.7 0.0 1e-24 87.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EJS44835.1 - 1.7e-08 34.6 0.0 3.5e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 EJS44835.1 - 0.0051 16.3 0.2 0.0076 15.7 0.2 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RRM_Rrp7 PF17799.1 EJS44835.1 - 0.09 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain ENT PF03735.14 EJS44835.1 - 0.15 12.1 0.4 30 4.8 0.0 2.6 2 2 0 2 2 2 0 ENT domain Carn_acyltransf PF00755.20 EJS44836.1 - 3.2e-202 673.3 0.2 3.6e-202 673.1 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-rbx1 PF12678.7 EJS44836.1 - 0.19 12.0 0.8 0.45 10.8 0.3 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain Oxysterol_BP PF01237.18 EJS44837.1 - 1.2e-129 432.4 0.0 2.2e-129 431.5 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 EJS44837.1 - 4.6e-11 42.8 0.2 0.00035 20.8 0.0 3.4 3 0 0 3 3 2 2 Ankyrin repeats (many copies) PH PF00169.29 EJS44837.1 - 1.5e-10 41.5 0.2 4.9e-10 39.9 0.2 2.0 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EJS44837.1 - 3.7e-10 40.1 0.1 0.00029 21.3 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EJS44837.1 - 5.1e-09 35.7 0.1 0.023 15.2 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EJS44837.1 - 6e-09 36.4 0.0 0.00082 19.9 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) PH_8 PF15409.6 EJS44837.1 - 1.2e-07 31.9 1.0 2.7e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Ank PF00023.30 EJS44837.1 - 6.5e-07 29.5 0.0 0.016 15.6 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat PH_11 PF15413.6 EJS44837.1 - 0.45 11.0 7.9 0.079 13.4 1.1 3.3 3 2 1 4 4 4 0 Pleckstrin homology domain CREPT PF16566.5 EJS44837.1 - 0.62 10.2 9.9 1.5 9.0 8.5 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ALMT PF11744.8 EJS44837.1 - 2.1 7.1 10.4 3.4 6.4 10.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Kelch_4 PF13418.6 EJS44838.1 - 7e-12 45.2 1.2 7.5e-05 22.7 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EJS44838.1 - 1.1e-10 41.2 1.1 0.004 17.1 0.0 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EJS44838.1 - 2.4e-09 36.6 1.9 0.0012 18.3 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EJS44838.1 - 1e-06 28.8 0.3 0.28 11.5 0.0 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EJS44838.1 - 5.8e-06 26.1 8.1 0.095 12.7 0.1 5.8 7 0 0 7 7 7 2 Kelch motif Kelch_6 PF13964.6 EJS44838.1 - 1.8e-05 24.9 0.7 6.8 7.1 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Peroxin-22 PF12827.7 EJS44839.1 - 1.9e-27 95.4 0.0 2.3e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family AMP-binding PF00501.28 EJS44840.1 - 1.2e-85 287.6 0.0 1.6e-85 287.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EJS44840.1 - 1.2e-24 87.1 0.1 2.1e-23 83.1 0.0 2.8 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EJS44840.1 - 1.3e-17 63.4 0.4 3.3e-17 62.1 0.4 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus LAMTOR PF15454.6 EJS44840.1 - 0.56 10.9 3.3 2.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator TRP PF06011.12 EJS44841.1 - 1.6e-152 508.1 35.3 2.2e-152 507.7 35.3 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EJS44841.1 - 1.4e-41 142.1 1.0 2.5e-41 141.3 1.0 1.4 1 0 0 1 1 1 1 ML-like domain TMEM132D_C PF15706.5 EJS44841.1 - 0.74 9.6 3.2 5.7 6.8 0.0 3.0 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Zn_clus PF00172.18 EJS44842.1 - 8.5e-12 45.0 10.5 1.5e-11 44.2 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EF_assoc_2 PF08356.12 EJS44843.1 - 3.5e-27 94.2 0.1 5.5e-26 90.4 0.0 2.4 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.12 EJS44843.1 - 2.1e-25 88.1 1.9 3.5e-25 87.4 1.3 1.7 2 0 0 2 2 1 1 EF hand associated Ras PF00071.22 EJS44843.1 - 4e-25 88.3 0.0 1.6e-13 50.6 0.0 3.0 2 1 0 2 2 2 2 Ras family Roc PF08477.13 EJS44843.1 - 1.1e-13 51.4 0.0 9.8e-06 25.8 0.0 3.3 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EJS44843.1 - 1.3e-06 28.5 0.0 0.043 13.9 0.0 3.1 2 2 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 EJS44843.1 - 2.2e-06 26.8 1.9 0.001 18.4 0.4 3.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EJS44843.1 - 3.4e-05 24.2 1.0 0.15 12.5 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair Dynamin_N PF00350.23 EJS44843.1 - 5.7e-05 23.2 0.1 0.13 12.4 0.0 2.4 2 0 0 2 2 2 2 Dynamin family EF-hand_6 PF13405.6 EJS44843.1 - 0.00024 20.8 2.5 0.029 14.3 0.2 3.3 2 0 0 2 2 2 1 EF-hand domain Arf PF00025.21 EJS44843.1 - 0.00025 20.6 0.0 0.0058 16.1 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 EJS44843.1 - 0.00059 20.3 0.0 0.9 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EJS44843.1 - 0.00074 19.5 2.8 0.21 11.5 0.0 4.1 4 1 2 6 6 5 1 RsgA GTPase AAA_28 PF13521.6 EJS44843.1 - 0.0023 18.2 0.0 2.9 8.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EJS44843.1 - 0.0038 17.7 0.0 3 8.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter EF-hand_5 PF13202.6 EJS44843.1 - 0.0039 16.6 0.8 0.025 14.1 0.8 2.6 1 0 0 1 1 1 1 EF hand AAA_29 PF13555.6 EJS44843.1 - 0.012 15.3 0.0 3.6 7.4 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EJS44843.1 - 0.015 15.9 0.0 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EJS44843.1 - 0.016 15.5 0.0 4.3 7.6 0.0 3.1 2 1 1 3 3 3 0 AAA domain AAA_15 PF13175.6 EJS44843.1 - 0.021 14.6 0.0 4.6 6.9 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EJS44843.1 - 0.028 14.6 0.0 10 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain MCM PF00493.23 EJS44843.1 - 0.037 13.1 0.0 3.6 6.6 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain FeoB_N PF02421.18 EJS44843.1 - 0.041 13.4 0.0 6.9 6.2 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF815 PF05673.13 EJS44843.1 - 0.055 12.6 0.0 3.7 6.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Septin PF00735.18 EJS44843.1 - 0.059 12.6 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Septin EF-hand_8 PF13833.6 EJS44843.1 - 0.059 13.2 1.6 0.39 10.6 0.3 2.7 2 0 0 2 2 2 0 EF-hand domain pair AAA_24 PF13479.6 EJS44843.1 - 0.072 12.8 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EJS44843.1 - 0.14 12.6 0.0 6.1 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 EJS44843.1 - 0.17 11.6 0.0 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein BolA PF01722.18 EJS44844.1 - 1.1e-26 92.9 0.1 1.4e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein GCV_H PF01597.19 EJS44845.1 - 4.9e-48 162.0 1.0 6e-48 161.8 1.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EJS44845.1 - 0.00014 21.6 1.6 0.00044 20.0 0.3 2.1 1 1 1 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 EJS44845.1 - 0.019 14.9 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF3453 PF11935.8 EJS44846.1 - 3.5e-59 200.2 1.2 1.2e-58 198.5 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Raftlin PF15250.6 EJS44846.1 - 0.23 10.2 3.3 0.33 9.7 3.3 1.2 1 0 0 1 1 1 0 Raftlin BSP_II PF05432.11 EJS44846.1 - 0.3 10.7 16.6 0.48 10.1 16.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Cwf_Cwc_15 PF04889.12 EJS44846.1 - 0.92 9.2 15.7 1.6 8.4 15.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 EJS44846.1 - 0.99 8.8 15.0 1.5 8.1 15.0 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EJS44846.1 - 2.9 7.1 15.1 4.6 6.5 15.1 1.2 1 0 0 1 1 1 0 BUD22 CCSAP PF15748.5 EJS44846.1 - 3.4 7.8 11.3 6.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 EJS44846.1 - 6.4 4.9 11.8 10 4.3 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 EJS44846.1 - 6.9 5.9 16.2 12 5.2 16.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 COPIIcoated_ERV PF07970.12 EJS44847.1 - 5.3e-74 248.8 0.1 6.4e-74 248.5 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EJS44847.1 - 1.9e-29 101.8 0.2 4.9e-29 100.5 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CDC24 PF06395.11 EJS44848.1 - 7.3e-36 122.3 1.0 1.1e-34 118.5 0.6 2.7 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 EJS44848.1 - 4.3e-31 108.6 5.4 4.3e-31 108.6 5.4 3.3 3 1 0 3 3 3 1 RhoGEF domain PH_10 PF15411.6 EJS44848.1 - 7.3e-26 90.8 9.9 4.8e-25 88.2 5.3 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PB1 PF00564.24 EJS44848.1 - 1.2e-05 25.1 0.0 6.3e-05 22.8 0.0 2.3 1 1 1 2 2 2 1 PB1 domain Sulfotransfer_4 PF17784.1 EJS44848.1 - 0.22 11.3 1.7 2.9 7.7 0.3 2.3 2 0 0 2 2 2 0 Sulfotransferase domain PH PF00169.29 EJS44848.1 - 0.3 11.6 4.7 0.37 11.3 0.1 3.0 2 1 0 2 2 2 0 PH domain Cyclin_N PF00134.23 EJS44849.1 - 3.3e-24 85.0 2.0 5.7e-24 84.3 2.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain RAMP PF04901.13 EJS44849.1 - 0.018 15.0 1.0 0.32 11.0 0.2 2.8 2 0 0 2 2 2 0 Receptor activity modifying family PK PF00224.21 EJS44850.1 - 1.7e-169 563.2 1.7 2.1e-169 562.9 1.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EJS44850.1 - 2.6e-32 111.5 0.0 7.9e-32 109.9 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EJS44850.1 - 9.3e-06 24.9 0.3 2.3e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Mtd_N PF18454.1 EJS44850.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain MMR_HSR1_Xtn PF16897.5 EJS44851.1 - 5.8e-37 125.9 0.0 1.2e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EJS44851.1 - 6.1e-22 77.4 0.1 1.1e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EJS44851.1 - 1.5e-19 70.2 0.0 3.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EJS44851.1 - 4.7e-10 39.2 0.0 1.4e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EJS44851.1 - 0.016 14.2 0.1 0.029 13.3 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EJS44851.1 - 0.016 15.3 0.4 4.2 7.4 0.3 2.4 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 EJS44851.1 - 0.056 13.7 0.1 9.3 6.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 EJS44852.1 - 8.6e-33 113.5 0.0 8.6e-33 113.5 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EJS44852.1 - 7.3e-22 77.5 0.0 2.6e-21 75.7 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EJS44852.1 - 1.3e-15 57.5 1.3 1.8e-09 37.9 0.0 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EJS44852.1 - 9.9e-08 32.1 0.2 2.8e-06 27.4 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EJS44852.1 - 1.5e-06 28.0 0.1 5.6e-06 26.2 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 EJS44852.1 - 0.00055 20.1 0.0 0.00055 20.1 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EJS44852.1 - 0.023 14.2 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Mis12 PF05859.12 EJS44853.1 - 6.5e-41 139.6 6.1 6.5e-41 139.6 6.1 2.2 1 1 1 2 2 2 1 Mis12 protein DUF1189 PF06691.11 EJS44853.1 - 0.18 11.3 1.2 0.25 10.9 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) BLOC1_2 PF10046.9 EJS44853.1 - 0.97 9.8 10.8 0.11 12.8 3.4 3.0 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HeLo PF14479.6 EJS44853.1 - 1.2 8.9 7.4 2.3 8.0 3.8 2.7 1 1 1 2 2 2 0 Prion-inhibition and propagation RRF_GI PF12614.8 EJS44853.1 - 5.3 7.2 7.4 12 6.1 1.1 2.9 2 1 1 3 3 3 0 Ribosome recycling factor SWIRM PF04433.17 EJS44854.1 - 3.1e-09 37.0 0.0 7.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain PhoLip_ATPase_C PF16212.5 EJS44856.1 - 1.4e-83 280.5 27.4 1.4e-83 280.5 27.4 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EJS44856.1 - 9.3e-24 82.9 5.5 2.5e-23 81.5 5.5 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EJS44856.1 - 1.2e-10 42.1 0.1 4.7e-05 23.8 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EJS44856.1 - 3.4e-09 36.7 0.0 1.1e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EJS44856.1 - 1.1e-06 28.4 0.1 2.9e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EJS44856.1 - 0.0017 18.1 0.5 0.013 15.2 0.4 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2204 PF09970.9 EJS44856.1 - 0.022 14.4 0.0 0.071 12.8 0.0 1.9 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Ribosomal_L28e PF01778.17 EJS44857.1 - 1.1e-39 135.8 2.2 1.1e-39 135.8 2.2 2.1 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 EJS44857.1 - 1.1e-30 106.2 14.7 1.1e-30 106.2 14.7 2.6 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EJS44857.1 - 0.0011 18.4 20.9 0.0014 18.1 20.9 1.2 1 0 0 1 1 1 1 BUD22 IMUP PF15761.5 EJS44857.1 - 0.0027 18.4 8.6 0.0027 18.4 8.6 2.1 2 0 0 2 2 2 1 Immortalisation up-regulated protein Ribosomal_L24e PF01246.20 EJS44857.1 - 0.037 14.3 2.3 0.21 11.8 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L24e DUF4611 PF15387.6 EJS44857.1 - 4.6 7.5 18.7 1.9 8.7 6.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RasGEF PF00617.19 EJS44858.1 - 2.6e-40 138.5 0.9 2.6e-40 138.5 0.9 2.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EJS44858.1 - 3.7e-13 49.6 7.1 2e-12 47.3 0.2 3.8 3 0 0 3 3 3 2 RasGEF N-terminal motif PMT PF02366.18 EJS44859.1 - 1.1e-98 329.7 21.6 1.1e-98 329.7 21.6 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EJS44859.1 - 6.5e-62 208.7 13.7 6.5e-62 208.7 13.7 2.6 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EJS44859.1 - 3.1e-24 85.8 1.4 3.3e-24 85.8 0.1 1.5 2 0 0 2 2 2 1 MIR domain Nucleoside_tran PF01733.18 EJS44860.1 - 4.3e-95 318.7 7.0 4.3e-95 318.7 7.0 1.6 2 0 0 2 2 2 1 Nucleoside transporter DUF5383 PF17355.2 EJS44860.1 - 3.2 8.2 4.9 1.3 9.4 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Exo_endo_phos PF03372.23 EJS44861.1 - 3.4e-23 82.4 0.8 2.2e-22 79.7 0.1 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EJS44861.1 - 6.5e-12 45.0 13.8 3e-07 30.1 6.9 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EJS44861.1 - 2.2e-10 40.6 3.8 7.9e-07 29.3 1.8 4.6 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EJS44861.1 - 7.9e-05 22.7 9.1 0.22 12.2 0.1 6.3 5 0 0 5 5 5 2 Leucine Rich Repeat RCC1 PF00415.18 EJS44862.1 - 3.6e-23 81.9 15.8 2.7e-11 43.9 0.3 4.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EJS44862.1 - 1.8e-18 65.8 27.7 5.6e-09 35.6 1.2 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat PAS PF00989.25 EJS44862.1 - 0.086 12.9 0.0 4.3 7.4 0.0 2.5 2 0 0 2 2 2 0 PAS fold SNF2_N PF00176.23 EJS44863.1 - 4.9e-61 206.4 0.4 9.5e-61 205.4 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EJS44863.1 - 6e-21 74.9 0.1 5.3e-17 62.2 0.1 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EJS44863.1 - 1.9e-12 47.5 0.0 6.9e-12 45.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EJS44863.1 - 5.8e-07 29.4 0.1 4.2e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Collagen PF01391.18 EJS44863.1 - 0.016 14.9 6.5 0.028 14.2 6.5 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) HhH-GPD PF00730.25 EJS44864.1 - 4.2e-23 81.9 0.0 8.6e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EJS44864.1 - 4e-08 32.7 0.0 1.7e-07 30.7 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EJS44864.1 - 0.08 13.6 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain SNARE PF05739.19 EJS44865.1 - 0.001 19.0 0.6 0.0024 17.9 0.6 1.6 1 0 0 1 1 1 1 SNARE domain Cys_Met_Meta_PP PF01053.20 EJS44866.1 - 1e-143 478.5 0.0 1.1e-143 478.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EJS44866.1 - 0.00015 21.0 0.1 0.00032 20.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EJS44866.1 - 0.0049 15.9 0.1 0.011 14.7 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V LMBR1 PF04791.16 EJS44867.1 - 1.8 7.4 6.9 2.7 6.8 6.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein MDM10 PF12519.8 EJS44868.1 - 1.8e-150 501.9 14.7 2.1e-150 501.7 14.7 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 SIR2_2 PF13289.6 EJS44868.1 - 0.037 14.2 0.1 0.077 13.1 0.1 1.5 1 0 0 1 1 1 0 SIR2-like domain Spo7 PF03907.13 EJS44869.1 - 1.8e-72 243.4 5.4 2.3e-72 243.0 5.4 1.1 1 0 0 1 1 1 1 Spo7-like protein FUN14 PF04930.15 EJS44870.1 - 3.3e-06 27.4 1.3 6.9e-06 26.4 1.3 1.5 1 0 0 1 1 1 1 FUN14 family EMP24_GP25L PF01105.24 EJS44871.1 - 1.8e-34 119.3 0.1 2.1e-34 119.1 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Fusion_gly PF00523.18 EJS44871.1 - 0.012 13.9 3.0 0.017 13.4 3.0 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF2673 PF10880.8 EJS44871.1 - 0.14 12.3 0.5 0.46 10.6 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) DUF2207 PF09972.9 EJS44871.1 - 3.4 6.3 7.3 0.12 11.2 0.5 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) HSP70 PF00012.20 EJS44872.1 - 2.3e-263 874.9 8.5 2.6e-263 874.7 8.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EJS44872.1 - 8.2e-18 64.3 0.0 1.6e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EJS44872.1 - 0.0017 18.1 0.0 0.0048 16.6 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EJS44872.1 - 0.0067 15.5 0.3 0.1 11.5 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 EJS44872.1 - 0.011 16.2 1.1 20 5.7 0.0 3.6 3 1 0 3 3 3 0 Cell division protein FtsA PilM_2 PF11104.8 EJS44872.1 - 0.021 13.9 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; BcrAD_BadFG PF01869.20 EJS44872.1 - 0.076 12.5 0.0 10 5.5 0.0 2.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 EJS44872.1 - 0.29 10.3 2.5 0.17 11.2 0.1 1.8 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase EMP24_GP25L PF01105.24 EJS44873.1 - 2.5e-47 161.2 0.0 3e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_UL73 PF03554.13 EJS44873.1 - 0.5 10.4 0.1 0.5 10.4 0.1 1.9 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein Rep_fac-A_C PF08646.10 EJS44874.1 - 2e-61 206.0 2.8 5.8e-59 198.0 1.2 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EJS44874.1 - 1.9e-33 114.3 0.9 6.2e-30 103.0 0.0 4.0 4 0 0 4 4 4 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 EJS44874.1 - 5.5e-14 51.9 0.7 1.9e-08 34.2 0.0 4.3 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EJS44874.1 - 6.8e-06 26.0 0.1 0.0011 18.8 0.0 3.4 3 1 0 3 3 3 1 Cell division control protein 24, OB domain 3 Rep-A_N PF04057.12 EJS44874.1 - 2.4e-05 24.3 0.1 6.7e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain IL12 PF03039.14 EJS44874.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Interleukin-12 alpha subunit DUF223 PF02721.14 EJS44874.1 - 0.0025 18.1 0.3 0.0025 18.1 0.3 2.4 3 0 0 3 3 3 1 Domain of unknown function DUF223 BRCA-2_OB1 PF09103.10 EJS44874.1 - 0.014 15.3 0.0 0.05 13.6 0.0 1.9 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 SAICAR_synt PF01259.18 EJS44875.1 - 1.7e-101 339.1 0.0 1.9e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase UPF0086 PF01868.16 EJS44875.1 - 0.045 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function UPF0086 Pkinase PF00069.25 EJS44876.1 - 1.4e-53 182.0 0.9 2.6e-52 177.8 0.9 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44876.1 - 6.8e-31 107.5 0.1 1.9e-29 102.8 0.1 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EJS44876.1 - 0.016 14.0 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase PPP5 PF08321.12 EJS44876.1 - 0.033 14.5 0.5 0.13 12.5 0.1 2.2 2 0 0 2 2 2 0 PPP5 TPR repeat region Kinase-like PF14531.6 EJS44876.1 - 0.047 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 EJS44877.1 - 4.8e-74 249.1 0.1 8.2e-74 248.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EJS44877.1 - 2.5e-52 177.7 0.0 3.8e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EJS44877.1 - 0.00046 19.6 0.2 0.012 14.9 0.0 2.7 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EJS44877.1 - 0.0042 15.9 0.1 0.0079 15.0 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase DUF4301 PF14134.6 EJS44877.1 - 0.05 12.4 0.8 0.093 11.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) ELFV_dehydrog PF00208.21 EJS44878.1 - 6.4e-82 274.9 2.9 7.9e-82 274.6 2.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EJS44878.1 - 5.8e-48 162.1 0.0 1.1e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Saccharomyces_arboricola_H-6-SacArb1.0/GCA_000292725.1_SacArb1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Saccharomyces_arboricola_H-6-SacArb1.0/GCA_000292725.1_SacArb1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Saccharomyces_arboricola_H-6-SacArb1.0/GCA_000292725.1_SacArb1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Saccharomyces_arboricola_H-6-SacArb1.0/GCA_000292725.1_SacArb1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 04:26:37 2019 # [ok]