# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- WD40 PF00400.27 EJS41220.1 - 3.4e-11 42.5 0.7 1.1e-05 25.1 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF3215 PF11503.3 EJS41221.1 - 1.3e-32 111.1 0.0 1.4e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) P34-Arc PF04045.9 EJS41222.1 - 4.4e-96 320.8 0.9 6.5e-96 320.2 0.6 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Ras PF00071.17 EJS41223.1 - 3.1e-56 189.2 0.3 3.1e-56 189.2 0.2 1.4 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EJS41223.1 - 4.9e-19 68.9 0.1 9.8e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS41223.1 - 1.9e-10 40.2 0.1 3.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EJS41223.1 - 4.9e-07 29.3 0.3 2.1e-06 27.2 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EJS41223.1 - 2e-05 24.5 0.1 4.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EJS41224.1 - 1.4e-63 213.1 0.5 1.7e-63 212.8 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS41224.1 - 2e-19 70.2 0.1 2.9e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS41224.1 - 3.9e-19 68.5 0.2 4.8e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EJS41224.1 - 8e-08 31.7 0.3 1e-07 31.3 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EJS41224.1 - 1.6e-07 30.7 0.1 1.8e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EJS41224.1 - 6.5e-06 25.6 0.6 8e-05 22.1 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EJS41224.1 - 8e-06 25.7 0.2 1.3e-05 25.1 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EJS41224.1 - 0.0019 17.4 0.3 0.028 13.6 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 EJS41224.1 - 0.0033 17.5 0.1 0.011 15.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EJS41224.1 - 0.0035 17.3 0.2 0.012 15.5 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EJS41224.1 - 0.0092 15.1 0.1 0.023 13.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MCM PF00493.18 EJS41224.1 - 0.023 13.5 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_29 PF13555.1 EJS41224.1 - 0.034 13.6 1.7 0.097 12.2 0.4 2.3 2 1 1 3 3 3 0 P-loop containing region of AAA domain AAA PF00004.24 EJS41224.1 - 0.042 14.0 0.1 0.64 10.2 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EJS41224.1 - 0.06 12.0 0.8 0.99 8.0 0.0 2.4 1 1 1 2 2 2 0 G-protein alpha subunit DUF815 PF05673.8 EJS41224.1 - 0.087 11.7 0.0 0.22 10.4 0.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF815) PWWP PF00855.12 EJS41225.1 - 5.8e-16 58.4 2.0 7.3e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 PWWP domain Ycf54 PF10674.4 EJS41225.1 - 0.026 14.6 0.1 0.067 13.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) NBP1 PF08537.5 EJS41226.1 - 1.6e-101 339.7 22.5 1.8e-101 339.6 15.6 1.0 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 Spore_III_AB PF09548.5 EJS41226.1 - 0.16 11.6 1.1 0.33 10.6 0.2 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) GAS PF13851.1 EJS41226.1 - 1.2 8.2 14.7 0.17 11.0 7.1 2.0 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.1 EJS41226.1 - 1.3 9.4 4.9 0.42 11.0 0.5 2.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.6 EJS41226.1 - 2.4 7.9 12.7 1.2 8.9 5.8 2.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) PIG-U PF06728.8 EJS41227.1 - 3.2e-100 335.6 46.4 3.9e-100 335.3 32.2 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Phosphorylase PF00343.15 EJS41228.1 - 0 1031.3 0.7 0 1031.0 0.5 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.20 EJS41229.1 - 1e-77 260.8 0.0 1.4e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41229.1 - 4.3e-32 111.2 0.0 6.4e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EJS41229.1 - 0.049 12.4 1.1 0.083 11.7 0.7 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 ORC4_C PF14629.1 EJS41230.1 - 3e-36 124.7 1.1 4.3e-36 124.2 0.8 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EJS41230.1 - 1.6e-06 28.2 0.0 4.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EJS41230.1 - 0.00024 20.8 0.6 0.00043 20.0 0.4 1.5 1 0 0 1 1 1 1 Archaeal ATPase DUF288 PF03385.12 EJS41230.1 - 0.023 13.1 0.0 0.042 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF288 Ins_allergen_rp PF06757.8 EJS41230.1 - 0.05 13.0 0.5 0.5 9.8 0.0 2.8 3 1 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification AAA_14 PF13173.1 EJS41230.1 - 0.055 13.3 0.3 0.37 10.7 0.2 2.6 1 1 0 1 1 1 0 AAA domain RRM_6 PF14259.1 EJS41231.1 - 6.1e-10 38.9 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS41231.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMS1_N PF10433.4 EJS41232.1 - 3.6e-46 157.3 8.6 3.3e-44 150.9 6.0 2.8 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ras PF00071.17 EJS41233.1 - 2.5e-55 186.2 0.0 3e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS41233.1 - 5.2e-16 59.2 0.0 9.1e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS41233.1 - 5.7e-07 28.9 0.0 8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EJS41233.1 - 0.00051 19.5 0.0 0.0024 17.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EJS41233.1 - 0.015 14.4 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region LEA_5 PF00477.12 EJS41233.1 - 0.027 14.7 1.2 0.052 13.8 0.8 1.5 1 0 0 1 1 1 0 Small hydrophilic plant seed protein SRPRB PF09439.5 EJS41233.1 - 0.065 12.4 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_S14 PF00253.16 EJS41234.1 - 1.3e-16 59.6 0.3 1.3e-16 59.6 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e PAPS_reduct PF01507.14 EJS41235.1 - 3.5e-44 150.6 0.0 4.7e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Cadherin_C PF01049.12 EJS41235.1 - 0.0077 16.2 0.1 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic region BCL9 PF11502.3 EJS41235.1 - 0.15 11.6 0.2 0.29 10.7 0.2 1.4 1 0 0 1 1 1 0 B-cell lymphoma 9 protein Pyridox_oxidase PF01243.15 EJS41237.1 - 3.2e-19 68.7 0.0 7.7e-19 67.4 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase L_biotic_typeA PF04604.8 EJS41237.1 - 0.18 11.4 2.3 0.35 10.5 0.3 2.1 2 0 0 2 2 2 0 Type-A lantibiotic AAA PF00004.24 EJS41238.1 - 7.4e-44 149.1 0.0 1.3e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EJS41238.1 - 2.6e-30 104.0 0.1 1.7e-29 101.4 0.1 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EJS41238.1 - 1.8e-23 82.1 3.2 1.5e-22 79.2 1.9 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EJS41238.1 - 4.4e-06 27.4 0.1 3.2e-05 24.7 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EJS41238.1 - 7.6e-06 26.1 0.4 0.00076 19.6 0.1 2.8 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EJS41238.1 - 9.3e-06 25.4 0.0 4.2e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EJS41238.1 - 1.3e-05 24.3 0.0 2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EJS41238.1 - 1.7e-05 24.3 0.0 4.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EJS41238.1 - 2e-05 24.4 0.0 6.3e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EJS41238.1 - 4.9e-05 22.8 0.1 0.02 14.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EJS41238.1 - 6.5e-05 22.9 0.0 0.00033 20.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 EJS41238.1 - 0.00011 21.0 0.0 0.00019 20.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EJS41238.1 - 0.00016 20.6 0.0 0.00037 19.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EJS41238.1 - 0.00022 21.3 0.2 0.0079 16.3 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_2 PF07724.9 EJS41238.1 - 0.00023 21.0 0.0 0.00092 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EJS41238.1 - 0.00044 20.1 0.1 0.0012 18.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EJS41238.1 - 0.0089 15.1 0.1 0.23 10.5 0.0 2.4 1 1 1 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EJS41238.1 - 0.0093 16.2 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EJS41238.1 - 0.014 15.1 0.3 0.46 10.1 0.0 2.6 2 1 1 3 3 2 0 Archaeal ATPase AAA_24 PF13479.1 EJS41238.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EJS41238.1 - 0.019 14.7 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EJS41238.1 - 0.02 14.0 0.1 3.4 6.7 0.0 2.3 1 1 1 2 2 2 0 KaiC Use1 PF09753.4 EJS41238.1 - 0.02 14.3 0.4 0.037 13.4 0.3 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 Torsin PF06309.6 EJS41238.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Torsin Mg_chelatase PF01078.16 EJS41238.1 - 0.028 13.5 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EJS41238.1 - 0.031 14.1 0.2 0.15 11.8 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EJS41238.1 - 0.035 13.3 0.0 0.081 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EJS41238.1 - 0.062 12.9 0.0 0.6 9.7 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 EJS41238.1 - 0.076 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EJS41238.1 - 0.078 12.4 0.0 0.23 10.8 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EJS41238.1 - 0.098 12.6 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EJS41238.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain CPT PF07931.7 EJS41238.1 - 0.14 11.8 0.0 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NBP1 PF08537.5 EJS41239.1 - 3e-55 187.7 17.4 4.3e-55 187.1 5.9 2.1 1 1 1 2 2 2 2 Fungal Nap binding protein NBP1 IncA PF04156.9 EJS41239.1 - 0.14 11.6 2.7 0.2 11.2 1.9 1.2 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EJS41239.1 - 0.19 10.1 0.6 0.23 9.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Prenyltrans PF00432.16 EJS41240.1 - 7e-63 207.8 2.8 2.8e-13 49.1 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EJS41240.1 - 1.3e-25 89.9 0.0 1.6e-12 47.8 0.0 3.8 1 1 3 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EJS41240.1 - 1.1e-06 28.5 0.0 3.8e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 Prenyltransferase-like WD40 PF00400.27 EJS41241.1 - 5.8e-52 171.8 14.2 3.9e-10 39.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nbas_N PF15492.1 EJS41241.1 - 0.021 13.9 0.1 1.6 7.7 0.0 2.6 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal HDA2-3 PF11496.3 EJS41242.1 - 3.8e-88 295.1 1.8 3.8e-88 295.1 1.3 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Sec23_trunk PF04811.10 EJS41243.1 - 2.4e-74 249.7 0.0 3.3e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EJS41243.1 - 1.5e-35 120.7 0.1 3.2e-35 119.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EJS41243.1 - 9.6e-29 99.7 0.1 2e-28 98.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EJS41243.1 - 1.1e-14 53.6 9.1 1.9e-14 52.8 6.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EJS41243.1 - 6.6e-12 44.9 0.0 1.7e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Glycos_transf_2 PF00535.21 EJS41244.1 - 6.8e-28 97.4 0.0 1.5e-27 96.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EJS41244.1 - 5.6e-07 29.6 0.0 7.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EJS41244.1 - 2.8e-06 26.6 0.0 4.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 EF-hand_7 PF13499.1 EJS41245.1 - 9e-07 28.9 0.2 0.0008 19.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EJS41245.1 - 0.00012 21.1 0.5 0.00012 21.1 0.4 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EJS41245.1 - 0.00014 21.4 4.1 0.00035 20.1 0.1 2.9 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.1 EJS41245.1 - 0.00035 19.7 0.7 0.00035 19.7 0.5 2.9 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 EJS41245.1 - 0.04 13.5 0.1 0.04 13.5 0.1 2.8 3 1 1 4 4 4 0 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EJS41245.1 - 0.13 12.3 1.2 0.17 11.9 0.2 1.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TPR_11 PF13414.1 EJS41246.1 - 3.5e-34 116.2 1.3 2.6e-06 26.9 0.0 10.1 7 3 4 11 11 11 8 TPR repeat TPR_19 PF14559.1 EJS41246.1 - 9.2e-24 83.5 3.1 5.4e-06 26.6 0.0 8.3 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EJS41246.1 - 8.2e-19 66.4 0.0 0.039 14.5 0.0 10.6 8 3 3 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 EJS41246.1 - 4.7e-18 65.3 0.0 0.0091 16.6 0.0 7.9 10 0 0 10 10 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EJS41246.1 - 7.3e-18 62.9 0.0 0.00035 20.2 0.0 11.1 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_1 PF00515.23 EJS41246.1 - 3.4e-17 61.2 2.8 2e-05 23.9 0.0 10.5 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_17 PF13431.1 EJS41246.1 - 8.2e-16 56.8 0.1 0.032 14.4 0.0 9.1 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EJS41246.1 - 3.1e-12 45.3 0.1 0.0019 17.8 0.0 7.8 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EJS41246.1 - 9.5e-09 35.0 2.0 0.054 13.4 0.0 7.1 6 3 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EJS41246.1 - 1.1e-08 34.8 0.0 0.011 15.5 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EJS41246.1 - 3.8e-06 26.9 0.7 45 4.8 0.0 8.1 9 0 0 9 9 7 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EJS41246.1 - 0.00082 19.6 0.1 0.4 10.8 0.0 3.9 4 0 0 4 4 4 1 Alkyl sulfatase dimerisation TPR_7 PF13176.1 EJS41246.1 - 0.001 18.7 0.0 0.61 10.0 0.0 5.0 4 0 0 4 4 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 EJS41246.1 - 0.0027 17.2 0.0 0.074 12.5 0.0 2.6 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.1 EJS41246.1 - 0.0028 17.7 1.1 0.84 9.7 0.0 4.5 6 0 0 6 6 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EJS41246.1 - 0.024 14.5 0.2 28 4.6 0.0 4.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Peptidase_M16 PF00675.15 EJS41247.1 - 2.8e-31 108.2 0.0 5e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EJS41247.1 - 2.5e-05 24.0 0.1 0.00024 20.8 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain MIP PF00230.15 EJS41248.1 - 2.3e-42 145.0 15.3 2.9e-42 144.6 10.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein DIM1 PF02966.11 EJS41249.1 - 6.4e-68 226.3 1.0 7.3e-68 226.1 0.7 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EJS41249.1 - 0.012 15.2 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin Dynamin_N PF00350.18 EJS41251.1 - 0.00063 19.6 0.8 0.28 10.9 0.0 2.7 3 0 0 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 EJS41251.1 - 0.001 19.0 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EJS41251.1 - 0.008 16.6 0.0 0.047 14.1 0.0 2.3 3 0 0 3 3 3 1 Miro-like protein AAA_28 PF13521.1 EJS41251.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 EJS41251.1 - 0.026 13.9 0.0 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 Ras family TFIIB PF00382.14 EJS41253.1 - 7.5e-44 147.4 3.0 7.2e-28 96.2 0.9 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EJS41253.1 - 2.8e-13 48.9 0.6 5.1e-13 48.1 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding SRP54 PF00448.17 EJS41254.1 - 7.9e-80 266.9 4.0 8.8e-80 266.7 0.2 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EJS41254.1 - 1.4e-24 86.3 13.0 1.4e-24 86.3 9.0 4.7 4 1 1 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 EJS41254.1 - 1.5e-16 60.2 3.0 5.6e-16 58.3 2.1 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_31 PF13614.1 EJS41254.1 - 4.6e-06 26.6 0.0 0.035 14.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain cobW PF02492.14 EJS41254.1 - 9e-06 25.2 2.2 4.3e-05 23.0 0.5 2.6 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EJS41254.1 - 9.6e-06 25.1 1.2 3.6e-05 23.2 0.1 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EJS41254.1 - 2e-05 24.2 0.1 7.5e-05 22.4 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EJS41254.1 - 2.9e-05 23.9 0.0 0.00011 22.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EJS41254.1 - 0.00062 20.5 0.0 0.0012 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 EJS41254.1 - 0.0017 17.6 8.5 1.5 7.9 0.0 4.3 4 1 0 4 4 4 2 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EJS41254.1 - 0.0029 17.0 0.3 0.0053 16.2 0.2 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EJS41254.1 - 0.0033 17.5 0.0 0.022 14.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EJS41254.1 - 0.0042 16.1 0.1 0.019 14.0 0.0 2.1 3 0 0 3 3 3 1 Zeta toxin MipZ PF09140.6 EJS41254.1 - 0.012 14.7 0.1 0.25 10.4 0.1 2.6 1 1 0 1 1 1 0 ATPase MipZ APS_kinase PF01583.15 EJS41254.1 - 0.018 14.7 0.0 0.046 13.3 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 EJS41254.1 - 0.018 15.3 0.0 0.084 13.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EJS41254.1 - 0.02 14.8 0.2 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EJS41254.1 - 0.022 13.5 3.5 0.025 13.3 0.1 2.7 3 1 0 3 3 3 0 ArgK protein VirE PF05272.6 EJS41254.1 - 0.037 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E AAA_23 PF13476.1 EJS41254.1 - 0.049 13.9 3.0 0.044 14.1 0.5 2.1 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EJS41254.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EJS41254.1 - 0.085 12.2 0.0 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.10 EJS41254.1 - 0.73 8.8 15.4 0.24 10.3 0.1 4.3 4 0 0 4 4 4 0 Anion-transporting ATPase AAA PF00004.24 EJS41254.1 - 1.7 8.8 8.1 0.79 9.9 0.6 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DIL PF01843.14 EJS41255.1 - 1.5e-08 34.4 5.6 0.00039 20.2 0.3 2.9 2 1 0 2 2 2 2 DIL domain Ank_5 PF13857.1 EJS41255.1 - 0.023 14.9 0.0 0.088 13.0 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Linker_histone PF00538.14 EJS41255.1 - 0.38 10.8 2.9 0.32 11.1 0.5 2.0 2 0 0 2 2 2 0 linker histone H1 and H5 family DUF2457 PF10446.4 EJS41255.1 - 0.69 8.5 12.4 1.3 7.6 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PHF5 PF03660.9 EJS41256.1 - 3.8e-50 168.4 12.5 4.1e-50 168.3 8.7 1.0 1 0 0 1 1 1 1 PHF5-like protein gag_pre-integrs PF13976.1 EJS41256.1 - 0.23 11.0 0.3 0.23 11.0 0.2 2.8 2 2 1 3 3 3 0 GAG-pre-integrase domain Prok-RING_1 PF14446.1 EJS41256.1 - 3.6 7.3 18.2 8.4 6.2 5.6 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Sec7 PF01369.15 EJS41257.1 - 5.3e-34 117.5 3.3 5.3e-34 117.5 2.3 2.3 3 0 0 3 3 3 1 Sec7 domain DUF3818 PF12825.2 EJS41258.1 - 2.7e-130 434.0 12.8 2.7e-130 434.0 8.9 2.3 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EJS41258.1 - 1e-46 157.9 1.0 3.1e-46 156.3 0.7 1.9 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EJS41258.1 - 3e-14 52.7 1.0 4.4e-13 49.0 0.7 3.0 1 1 0 1 1 1 1 PX domain Peptidase_M35 PF02102.10 EJS41258.1 - 0.014 14.0 0.6 0.027 13.1 0.4 1.4 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family L51_S25_CI-B8 PF05047.11 EJS41259.1 - 2.6e-13 49.4 0.0 4.4e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain KID PF02524.9 EJS41259.1 - 0.19 11.9 1.8 17 6.1 0.1 2.9 2 0 0 2 2 2 0 KID repeat Ribosomal_L5_C PF00673.16 EJS41260.1 - 5.8e-23 80.4 0.0 8.7e-23 79.8 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EJS41260.1 - 1.3e-20 72.9 0.1 3.4e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Proteasome PF00227.21 EJS41261.1 - 2.6e-49 167.0 0.1 3.2e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.20 EJS41262.1 - 5.6e-21 74.8 0.0 8.3e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41262.1 - 4.5e-09 35.7 0.0 1.6e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS41262.1 - 0.00053 19.0 0.0 0.00084 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EJS41262.1 - 0.021 14.5 0.0 0.086 12.5 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family EcKinase PF02958.15 EJS41262.1 - 0.17 10.9 0.8 0.38 9.8 0.1 1.8 2 0 0 2 2 2 0 Ecdysteroid kinase zf-CCCH PF00642.19 EJS41263.1 - 3.9e-14 51.9 26.6 0.0002 20.9 0.2 5.5 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RPN7 PF10602.4 EJS41264.1 - 9.7e-54 181.4 3.2 9.7e-54 181.4 2.2 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EJS41264.1 - 2.9e-15 56.4 0.1 1.4e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_8 PF13181.1 EJS41264.1 - 6.8e-06 25.4 0.5 2.4e-05 23.7 0.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EJS41264.1 - 9.2e-06 25.5 1.0 0.00043 20.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EJS41264.1 - 0.0002 21.0 1.3 0.0032 17.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EJS41264.1 - 0.00024 20.6 0.2 0.035 13.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EJS41264.1 - 0.002 18.5 0.0 0.17 12.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EJS41264.1 - 0.0024 17.3 1.9 0.0031 17.0 0.2 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EJS41264.1 - 0.015 14.9 0.2 0.049 13.2 0.1 1.8 1 0 0 1 1 1 0 TPR repeat TPR_21 PF09976.4 EJS41264.1 - 0.031 14.2 0.1 0.078 12.9 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1897 PF09005.5 EJS41264.1 - 0.031 13.7 1.0 0.18 11.3 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) Ank_2 PF12796.2 EJS41264.1 - 0.053 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) TPR_19 PF14559.1 EJS41264.1 - 0.087 13.1 3.9 0.11 12.8 0.2 2.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EJS41264.1 - 0.094 13.4 0.1 0.68 10.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EJS41264.1 - 0.096 12.9 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EJS41264.1 - 0.14 12.1 0.1 0.91 9.5 0.0 2.4 3 0 0 3 3 2 0 Tetratricopeptide repeat ASD2 PF08687.6 EJS41264.1 - 0.35 10.1 4.1 0.94 8.7 2.8 1.7 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 DUF1746 PF08508.5 EJS41265.1 - 0.00037 20.4 0.6 2.6 8.0 0.0 3.1 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1746) RNA_pol_A_bac PF01000.21 EJS41266.1 - 3.1e-29 101.3 0.0 5.6e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EJS41266.1 - 4.4e-15 54.5 0.0 5.9e-15 54.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Hormone_4 PF00220.12 EJS41266.1 - 1 9.2 3.0 21 5.1 0.3 2.8 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain Pkinase PF00069.20 EJS41267.1 - 1.5e-53 181.5 0.4 1.6e-52 178.2 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41267.1 - 3.7e-27 95.0 0.1 4.3e-19 68.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EJS41267.1 - 1.4e-05 25.4 2.1 4.3e-05 23.9 1.4 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EJS41267.1 - 0.004 16.1 0.0 0.04 12.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EJS41267.1 - 0.041 12.9 0.0 0.08 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS41267.1 - 0.13 11.9 0.3 0.57 9.8 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family RRM_1 PF00076.17 EJS41268.1 - 8.6e-69 227.1 13.0 6.5e-17 60.9 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS41268.1 - 1e-63 211.2 4.0 1.1e-15 57.2 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS41268.1 - 6.9e-38 128.2 0.1 1.6e-09 37.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EJS41268.1 - 0.00049 19.8 0.0 2.7 7.8 0.0 3.6 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EJS41268.1 - 0.001 18.7 1.0 3.1 7.6 0.0 4.0 4 0 0 4 4 4 2 Limkain b1 SVS_QK PF10578.4 EJS41268.1 - 5.1 7.6 5.5 5 7.7 0.1 3.2 3 0 0 3 3 3 0 Seminal vesicle protein repeat TRAM_LAG1_CLN8 PF03798.11 EJS41269.1 - 2.2e-30 105.6 17.9 2.2e-30 105.6 12.4 1.4 2 0 0 2 2 2 1 TLC domain IF-2B PF01008.12 EJS41270.1 - 4.2e-91 304.8 0.0 4.9e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyclin_N PF00134.18 EJS41271.1 - 1.1e-40 138.1 0.5 3.1e-40 136.6 0.2 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EJS41271.1 - 9.1e-31 106.2 0.0 2.3e-30 104.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zot PF05707.7 EJS41271.1 - 0.052 13.0 0.2 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Peptidase_M16 PF00675.15 EJS41272.1 - 6.3e-39 133.1 0.0 1.4e-37 128.7 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EJS41272.1 - 1.3e-15 57.5 4.5 1.5e-05 24.7 0.0 5.2 4 2 0 4 4 4 3 Peptidase M16 inactive domain DUF2807 PF10988.3 EJS41272.1 - 0.047 13.2 1.1 0.075 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2807) LETM1 PF07766.8 EJS41273.1 - 2.1e-90 302.4 3.4 3.7e-90 301.6 2.4 1.3 1 0 0 1 1 1 1 LETM1-like protein GPAT_N PF14829.1 EJS41273.1 - 0.0034 17.0 0.1 0.084 12.5 0.0 2.5 2 0 0 2 2 2 1 Glycerol-3-phosphate acyltransferase N-terminal RNA_pol_3_Rpc31 PF11705.3 EJS41273.1 - 1.2 9.0 10.1 3.3 7.5 0.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 LSM14 PF12701.2 EJS41274.1 - 4.3e-25 87.3 0.1 1.5e-24 85.6 0.0 2.0 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EJS41274.1 - 1.2e-12 48.2 15.7 1.2e-12 48.2 10.9 4.0 4 1 0 4 4 4 1 FDF domain SM-ATX PF14438.1 EJS41274.1 - 0.028 14.3 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 Ataxin 2 SM domain Rotamase_2 PF13145.1 EJS41274.1 - 1.9 9.1 11.0 0.24 12.0 1.7 2.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain Pox_Ag35 PF03286.9 EJS41274.1 - 5.5 6.4 17.7 1.6 8.2 8.2 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Acetyltransf_1 PF00583.19 EJS41275.1 - 1.1e-10 41.3 0.0 1.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EJS41275.1 - 9.8e-06 25.2 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EJS41275.1 - 0.00012 22.1 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EJS41275.1 - 0.0043 17.1 0.0 0.0066 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EJS41275.1 - 0.044 13.6 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tom5 PF10642.4 EJS41276.1 - 1.7e-26 91.5 1.0 1.8e-26 91.4 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase DUF3639 PF12341.3 EJS41277.1 - 2.8e-10 39.9 0.5 5.7e-10 39.0 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) Apc4_WD40 PF12894.2 EJS41277.1 - 0.054 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EJS41278.1 - 3.8e-23 80.4 5.8 2.5e-07 30.3 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Ammonium_transp PF00909.16 EJS41279.1 - 9.7e-123 409.5 26.1 1.1e-122 409.3 18.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Colicin PF01024.14 EJS41279.1 - 0.12 11.9 1.3 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Colicin pore forming domain Acyltransferase PF01553.16 EJS41281.1 - 4.8e-11 42.2 0.0 7.3e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Kinesin PF00225.18 EJS41282.1 - 1.3e-105 352.8 7.6 1.3e-105 352.8 5.3 2.5 2 1 1 3 3 3 1 Kinesin motor domain Rrp15p PF07890.7 EJS41283.1 - 5.7e-32 110.5 14.5 5.7e-32 110.5 10.0 2.4 2 1 0 2 2 2 1 Rrp15p Trypan_PARP PF05887.6 EJS41283.1 - 0.51 10.1 7.2 0.84 9.4 5.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CBF PF03914.12 EJS41284.1 - 9.4e-46 155.2 0.4 2e-45 154.2 0.3 1.6 1 0 0 1 1 1 1 CBF/Mak21 family BID PF06393.6 EJS41284.1 - 0.13 11.5 0.1 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) Asn_synthase PF00733.16 EJS41285.1 - 1.1e-69 234.7 0.0 1.5e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EJS41285.1 - 4.3e-33 113.6 0.0 6.9e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EJS41285.1 - 8.8e-26 90.4 0.0 2e-25 89.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EJS41285.1 - 1.1e-06 28.0 0.0 1.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EJS41285.1 - 4.2e-06 25.7 0.0 0.027 13.1 0.0 2.9 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EJS41285.1 - 0.031 13.1 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase DUF2305 PF10230.4 EJS41286.1 - 1.8e-72 243.9 4.0 2e-72 243.7 2.8 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EJS41286.1 - 1.3e-08 35.0 0.0 1.6e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EJS41286.1 - 0.0017 16.8 0.1 0.0029 16.1 0.0 1.4 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.2 EJS41286.1 - 0.0031 17.2 0.0 0.0048 16.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 EJS41286.1 - 0.019 13.8 2.6 0.82 8.4 0.1 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF1749 PF08538.5 EJS41286.1 - 0.051 12.4 0.3 0.099 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.8 EJS41286.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EJS41286.1 - 0.093 12.3 1.0 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 Lipase (class 3) MARVEL PF01284.18 EJS41287.1 - 2.8e-29 101.8 12.0 3.7e-29 101.4 8.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Fer4_5 PF12801.2 EJS41287.1 - 0.044 13.5 1.2 0.044 13.5 0.8 2.3 1 1 1 2 2 2 0 4Fe-4S binding domain SH3_1 PF00018.23 EJS41288.1 - 5.3e-14 51.3 0.0 9.7e-14 50.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EJS41288.1 - 3.8e-12 45.6 0.0 5.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EJS41288.1 - 3.9e-12 45.4 0.0 5.5e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.4 EJS41288.1 - 0.0032 17.5 4.8 0.0043 17.1 3.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF605 PF04652.11 EJS41288.1 - 0.0083 15.5 12.9 0.0087 15.5 9.0 1.2 1 0 0 1 1 1 1 Vta1 like Pex14_N PF04695.8 EJS41288.1 - 0.012 15.6 8.1 0.024 14.6 5.6 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 EJS41288.1 - 0.022 13.0 13.9 0.023 12.9 9.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NCA2 PF08637.5 EJS41289.1 - 3.9e-108 360.7 4.2 3.9e-108 360.7 2.9 2.0 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Med12 PF09497.5 EJS41289.1 - 0.072 13.0 2.6 1.3 9.0 0.2 3.3 3 1 1 4 4 4 0 Transcription mediator complex subunit Med12 MFS_1 PF07690.11 EJS41290.1 - 2.8e-31 108.5 32.3 2.8e-31 108.5 22.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF946 PF06101.6 EJS41291.1 - 2.5e-05 22.4 3.5 0.00073 17.6 1.2 2.2 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) SKN1 PF03935.10 EJS41292.1 - 3e-257 853.7 5.2 3.6e-257 853.4 3.6 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SUV3_C PF12513.3 EJS41293.1 - 5.3e-18 64.2 1.9 2.2e-17 62.2 1.3 2.2 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EJS41293.1 - 3.1e-14 52.5 0.0 6.7e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Thiolase_N PF00108.18 EJS41294.1 - 6.5e-102 340.0 3.2 8.6e-102 339.6 2.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EJS41294.1 - 2.6e-46 156.0 1.3 9.7e-46 154.1 0.2 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EJS41294.1 - 3.8e-06 26.5 1.6 9.9e-06 25.2 1.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Pkinase PF00069.20 EJS41295.1 - 4.7e-47 160.3 1.1 4.7e-47 160.3 0.8 2.9 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41295.1 - 5e-20 71.6 0.2 1.3e-18 67.0 0.1 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS41295.1 - 3.6e-05 22.8 0.0 0.0001 21.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EJS41295.1 - 0.019 14.7 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family TMEM51 PF15345.1 EJS41295.1 - 4.6 6.8 7.7 7.9 6.0 5.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Apis_Csd PF11671.3 EJS41296.1 - 0.018 14.8 0.6 0.027 14.2 0.4 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Spo7_2_N PF15407.1 EJS41296.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 ABC2_membrane_3 PF12698.2 EJS41296.1 - 0.14 11.1 1.0 0.17 10.9 0.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ATP-synt_E_2 PF08112.6 EJS41296.1 - 0.15 12.1 4.0 5.6 7.1 0.0 2.7 1 1 1 2 2 2 0 ATP synthase epsilon subunit Defensin_3 PF08131.6 EJS41296.1 - 0.57 10.2 2.6 18 5.4 0.2 2.7 2 0 0 2 2 2 0 Defensin-like peptide family Ribosomal_S16 PF00886.14 EJS41299.1 - 9.2e-27 92.5 0.2 1.2e-26 92.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 NUC173 PF08161.7 EJS41300.1 - 7.2e-73 244.1 0.1 7.7e-71 237.5 0.2 3.1 2 0 0 2 2 2 2 NUC173 domain HEAT PF02985.17 EJS41300.1 - 0.0041 17.0 0.2 10 6.4 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat Bromo_TP PF07524.8 EJS41301.1 - 1.3e-08 34.3 0.1 1.1e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated XAP5 PF04921.9 EJS41301.1 - 9.5 5.7 13.7 1.4 8.3 6.9 1.6 2 0 0 2 2 2 0 XAP5, circadian clock regulator Clat_adaptor_s PF01217.15 EJS41302.1 - 2.3e-18 66.2 0.7 3.4e-18 65.7 0.5 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CHASE4 PF05228.8 EJS41302.1 - 0.094 12.2 0.1 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 CHASE4 domain zf-TFIIIC PF12660.2 EJS41303.1 - 2.4e-08 33.7 0.0 5.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Patched PF02460.13 EJS41304.1 - 1.4e-59 201.8 22.6 5.8e-57 193.2 15.7 2.7 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EJS41304.1 - 8.3e-39 132.4 5.5 8.3e-39 132.4 3.8 3.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EJS41304.1 - 3.9e-08 31.2 21.4 1.1e-07 29.7 10.9 2.6 3 0 0 3 3 3 2 AcrB/AcrD/AcrF family RLL PF10036.4 EJS41304.1 - 0.33 10.3 0.8 0.64 9.3 0.0 1.7 2 0 0 2 2 2 0 Putative carnitine deficiency-associated protein Pil1 PF13805.1 EJS41305.1 - 5.1e-152 504.6 0.6 5.9e-152 504.4 0.4 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.5 EJS41305.1 - 0.022 14.5 0.1 0.14 12.0 0.1 2.3 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit EAP30 PF04157.11 EJS41307.1 - 3.5e-49 166.9 0.1 3.9e-49 166.8 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Sulfate_transp PF00916.15 EJS41308.1 - 2.1e-66 223.8 9.5 3.6e-66 223.0 6.6 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EJS41308.1 - 2.4e-27 94.4 3.7 2.4e-27 94.4 2.6 2.6 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EJS41308.1 - 9.9e-26 89.4 0.2 2.3e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 STAS domain Spore_YabQ PF09578.5 EJS41308.1 - 6.6e-05 22.7 6.2 0.0038 17.1 1.6 2.9 2 0 0 2 2 2 2 Spore cortex protein YabQ (Spore_YabQ) DUF1072 PF06380.6 EJS41308.1 - 1.8 8.2 8.9 0.28 10.8 1.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) ETF_alpha PF00766.14 EJS41309.1 - 1.7e-33 114.0 0.1 3.2e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EJS41309.1 - 1e-30 106.5 0.0 2.5e-30 105.3 0.0 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ICL PF00463.16 EJS41311.1 - 1e-169 565.1 0.0 1.2e-169 564.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EJS41311.1 - 7.3e-08 31.9 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Rad21_Rec8_N PF04825.8 EJS41312.1 - 5.2e-18 65.0 0.9 9e-17 61.0 0.6 2.4 1 1 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Copper-fist PF00649.13 EJS41313.1 - 3e-22 77.5 1.1 8.2e-22 76.1 0.8 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain RNA_pol_Rpb2_6 PF00562.23 EJS41314.1 - 1.5e-114 382.7 0.0 2.1e-114 382.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EJS41314.1 - 2.5e-55 186.5 0.1 3.5e-55 186.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EJS41314.1 - 1.4e-39 135.4 0.0 4.7e-39 133.7 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EJS41314.1 - 7.7e-25 86.4 0.0 5.7e-24 83.6 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EJS41314.1 - 1.1e-22 79.7 0.0 2.2e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EJS41314.1 - 2.8e-16 59.5 0.0 3.4e-15 56.0 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EJS41314.1 - 5.8e-06 26.1 0.1 1.3e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Mito_carr PF00153.22 EJS41315.1 - 2.3e-75 248.3 1.0 4.5e-27 93.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1478 PF07349.6 EJS41315.1 - 0.07 12.4 0.4 2.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1478) zf-C2H2 PF00096.21 EJS41316.1 - 1.8e-09 37.3 9.1 0.00026 21.1 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS41316.1 - 4.4e-06 26.6 6.5 0.0066 16.7 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EJS41316.1 - 0.00052 20.1 5.7 0.0056 16.8 0.3 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EJS41316.1 - 0.0018 18.4 0.3 0.0018 18.4 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EJS41316.1 - 0.015 15.3 2.8 0.42 10.8 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EJS41316.1 - 0.084 13.1 6.0 2.2 8.6 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.10 EJS41316.1 - 0.11 12.2 7.3 0.18 11.6 1.3 2.4 1 1 1 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 EJS41317.1 - 2.7e-10 39.9 12.0 4.3e-05 23.5 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EJS41317.1 - 0.00012 22.1 1.0 0.00012 22.1 0.7 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EJS41317.1 - 0.0002 21.4 18.3 0.00062 19.9 0.8 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EJS41317.1 - 0.0012 19.0 6.6 0.0031 17.6 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EJS41317.1 - 0.016 15.3 5.5 0.44 10.7 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EJS41317.1 - 0.17 11.6 9.5 1.1 9.0 0.5 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 EJS41317.1 - 2.5 7.8 6.3 19 5.0 1.1 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 EJS41317.1 - 8.8 6.7 15.1 7.2 7.0 1.9 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain eIF-6 PF01912.13 EJS41318.1 - 2.6e-85 284.5 0.5 3.3e-85 284.2 0.3 1.1 1 0 0 1 1 1 1 eIF-6 family MCM PF00493.18 EJS41319.1 - 6.1e-140 465.7 0.1 9.1e-140 465.1 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EJS41319.1 - 1.7e-22 80.1 1.8 1.7e-22 80.1 1.3 2.7 3 1 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 EJS41319.1 - 4.5e-06 26.4 0.0 2.8e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EJS41319.1 - 8.8e-06 25.0 0.0 0.00036 19.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EJS41319.1 - 0.0036 16.9 0.0 0.012 15.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EJS41319.1 - 0.08 12.4 0.1 5 6.5 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain ATP-synt_G PF04718.10 EJS41320.1 - 1.5e-32 112.3 0.4 1.7e-32 112.1 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DUF2743 PF10899.3 EJS41320.1 - 0.043 13.2 0.9 0.069 12.5 0.5 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2743) Fungal_trans PF04082.13 EJS41321.1 - 4.6e-74 248.5 2.1 4.6e-74 248.5 1.5 2.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EJS41321.1 - 3.1e-07 30.2 9.6 0.00087 19.4 3.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EJS41321.1 - 5.4e-07 29.5 11.5 0.0012 19.0 3.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type GTPase_binding PF09027.5 EJS41321.1 - 0.023 14.2 0.3 0.15 11.6 0.1 2.4 2 0 0 2 2 2 0 GTPase binding zf-C2H2_6 PF13912.1 EJS41321.1 - 0.13 12.2 1.2 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger MRG PF05712.8 EJS41322.1 - 1.5e-52 177.3 0.4 2.4e-52 176.7 0.3 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EJS41322.1 - 3.9e-06 26.4 0.6 9.5e-06 25.2 0.4 1.7 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Macoilin PF09726.4 EJS41322.1 - 0.019 13.3 5.2 0.022 13.0 3.6 1.1 1 0 0 1 1 1 0 Transmembrane protein NPDC1 PF06809.6 EJS41322.1 - 0.048 12.4 0.2 0.075 11.8 0.1 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Peptidase_M41 PF01434.13 EJS41323.1 - 1.5e-71 240.2 0.3 2.5e-71 239.5 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EJS41323.1 - 1.6e-40 138.3 0.0 3.6e-40 137.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EJS41323.1 - 3.7e-05 23.7 0.4 0.00014 21.8 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EJS41323.1 - 0.00011 22.3 0.6 0.034 14.2 0.1 3.1 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EJS41323.1 - 0.00021 20.1 0.0 0.00039 19.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EJS41323.1 - 0.00052 20.8 0.0 0.0021 18.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EJS41323.1 - 0.00073 18.6 0.0 0.0031 16.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EJS41323.1 - 0.0014 18.3 1.5 0.004 16.8 1.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EJS41323.1 - 0.0033 17.1 0.1 0.011 15.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EJS41323.1 - 0.0048 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EJS41323.1 - 0.0049 16.2 1.5 0.14 11.5 0.4 2.4 1 1 1 2 2 2 1 AAA domain SpoU_sub_bind PF08032.7 EJS41323.1 - 0.013 15.6 0.2 4.6 7.4 0.3 3.4 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding AAA_18 PF13238.1 EJS41323.1 - 0.015 15.5 0.2 0.065 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EJS41323.1 - 0.017 14.2 0.0 0.04 13.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 EJS41323.1 - 0.025 14.4 0.0 0.097 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EJS41323.1 - 0.035 13.9 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EJS41323.1 - 0.04 13.0 0.0 0.42 9.6 0.0 2.3 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.16 EJS41323.1 - 0.04 13.0 0.2 0.1 11.7 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EJS41323.1 - 0.083 12.1 0.6 0.3 10.2 0.2 1.9 2 0 0 2 2 2 0 PhoH-like protein Cyclin_N PF00134.18 EJS41324.1 - 3.2e-11 42.8 1.5 6e-11 42.0 0.7 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 EJS41324.1 - 0.0017 18.0 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat MRP-L28 PF09812.4 EJS41324.1 - 0.0094 15.7 1.1 0.018 14.9 0.8 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 GvpK PF05121.7 EJS41324.1 - 0.083 12.7 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Gas vesicle protein K Glyco_hydro_65m PF03632.10 EJS41325.1 - 7.5e-105 350.6 2.1 3.2e-104 348.5 1.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EJS41325.1 - 2.8e-66 223.4 0.0 7.3e-66 222.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 EJS41325.1 - 5.6e-13 48.7 0.6 1.1e-12 47.7 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain DUF551 PF04448.7 EJS41325.1 - 0.11 13.2 0.0 1.5 9.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF551) DUF1304 PF06993.7 EJS41326.1 - 0.036 13.7 0.1 0.062 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Adaptin_N PF01602.15 EJS41327.1 - 7.7e-131 436.9 17.4 7.7e-131 436.9 12.0 1.4 1 1 1 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EJS41327.1 - 4.2e-14 52.8 0.2 9e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Arrestin_C PF02752.17 EJS41328.1 - 4.9e-15 55.8 1.6 4.9e-15 55.8 1.1 4.2 2 2 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EJS41328.1 - 0.00036 20.3 0.0 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain NOA36 PF06524.7 EJS41328.1 - 4.3 6.5 12.9 9.5 5.3 9.0 1.5 1 0 0 1 1 1 0 NOA36 protein Lgl_C PF08596.5 EJS41329.1 - 1.4e-147 491.3 0.3 1.8e-146 487.6 0.0 2.3 2 1 1 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal tRNA-synt_His PF13393.1 EJS41330.1 - 3.8e-40 137.8 0.0 4.4e-39 134.3 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EJS41330.1 - 2.7e-19 69.4 0.0 1.5e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EJS41330.1 - 3.3e-12 46.1 0.1 6.5e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EJS41330.1 - 0.00017 20.4 0.1 0.0033 16.2 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EJS41330.1 - 0.023 13.9 0.0 0.051 12.7 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Gln-synt_C PF00120.19 EJS41331.1 - 3e-64 216.6 0.0 3.7e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EJS41331.1 - 4.2e-20 71.0 0.0 1.4e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain V-ATPase_H_N PF03224.9 EJS41332.1 - 4.2e-64 216.6 14.8 4.2e-64 216.6 10.2 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EJS41332.1 - 3e-41 140.0 0.2 3e-41 140.0 0.1 3.1 3 1 2 5 5 5 1 V-ATPase subunit H HEAT_2 PF13646.1 EJS41332.1 - 0.035 14.3 0.1 21 5.4 0.0 3.7 3 1 1 4 4 4 0 HEAT repeats Y_phosphatase3 PF13350.1 EJS41332.1 - 0.05 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family CAP-ZIP_m PF15255.1 EJS41333.1 - 0.22 11.4 1.7 0.3 11.0 0.7 1.5 1 1 1 2 2 2 0 WASH complex subunit CAP-Z interacting, central region Evr1_Alr PF04777.8 EJS41334.1 - 1.3e-24 85.8 0.1 2e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Toxin-deaminase PF14424.1 EJS41334.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases TIP41 PF04176.8 EJS41335.1 - 9.6e-72 240.0 4.6 1.4e-71 239.4 3.2 1.2 1 0 0 1 1 1 1 TIP41-like family SAC3_GANP PF03399.11 EJS41336.1 - 4.3e-49 166.8 7.6 5.8e-49 166.4 5.3 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 EJS41336.1 - 0.026 14.8 2.0 0.12 12.6 0.3 2.4 2 0 0 2 2 2 0 PCI domain PCI_Csn8 PF10075.4 EJS41336.1 - 0.044 13.5 7.4 0.025 14.3 2.7 2.1 1 1 1 2 2 2 0 COP9 signalosome, subunit CSN8 tRNA-synt_2d PF01409.15 EJS41337.1 - 2.9e-47 160.9 0.1 2e-26 92.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EJS41337.1 - 1.2e-26 92.6 0.1 8.2e-26 90.0 0.0 2.4 2 1 1 3 3 3 1 Ferredoxin-fold anticodon binding domain DUF3811 PF11656.3 EJS41337.1 - 0.02 14.9 0.6 0.061 13.3 0.0 2.1 2 0 0 2 2 2 0 YjbD family (DUF3811) FAD_binding_1 PF00667.15 EJS41338.1 - 1.8e-31 109.3 0.0 4.5e-31 107.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EJS41338.1 - 4.3e-22 78.6 0.0 1.2e-21 77.1 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EJS41338.1 - 1e-12 48.5 0.0 3.1e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 EJS41338.1 - 0.049 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 NrdI Flavodoxin like ATG11 PF10377.4 EJS41339.1 - 1.2e-40 138.3 1.3 1.9e-40 137.7 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein 11 HMG_box PF00505.14 EJS41340.1 - 5.3e-26 90.6 1.8 5.3e-26 90.6 1.3 1.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EJS41340.1 - 1.4e-19 70.1 1.5 2e-19 69.7 1.0 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EJS41340.1 - 0.00047 19.8 1.2 0.00063 19.4 0.1 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box 5 YABBY PF04690.8 EJS41340.1 - 0.11 12.7 0.4 0.13 12.5 0.2 1.2 1 1 0 1 1 1 0 YABBY protein Pkinase PF00069.20 EJS41341.1 - 6.4e-60 202.4 0.0 8e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41341.1 - 1.1e-29 103.3 0.0 1.5e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EJS41341.1 - 0.084 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SIP1 PF04938.7 EJS41342.1 - 5.5e-08 32.4 1.8 9.1e-06 25.1 1.3 2.6 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Mito_carr PF00153.22 EJS41343.1 - 3.5e-60 199.7 1.6 3.8e-21 74.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CM_2 PF01817.16 EJS41344.1 - 7.5e-13 48.3 0.0 8.3e-08 32.2 0.0 3.2 2 1 0 2 2 2 2 Chorismate mutase type II Baculo_FP PF03258.9 EJS41344.1 - 0.013 14.5 1.6 0.013 14.5 1.1 2.1 2 0 0 2 2 2 0 Baculovirus FP protein HMG_box PF00505.14 EJS41345.1 - 9.8e-18 64.1 1.4 2.8e-17 62.7 0.9 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EJS41345.1 - 2.6e-06 27.7 0.2 7.2e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain Trypan_PARP PF05887.6 EJS41345.1 - 0.28 10.9 2.3 0.46 10.2 1.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BAF1_ABF1 PF04684.8 EJS41345.1 - 7.6 5.2 11.4 11 4.7 7.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NARP1 PF12569.3 EJS41345.1 - 9.4 4.8 11.9 7.2 5.2 7.3 1.5 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Fe-S_biosyn PF01521.15 EJS41346.1 - 2e-13 50.2 0.1 5.8e-12 45.5 0.1 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Hist_deacetyl PF00850.14 EJS41347.1 - 3.2e-64 217.1 0.2 5.8e-64 216.3 0.2 1.4 1 1 0 1 1 1 1 Histone deacetylase domain Spermine_synth PF01564.12 EJS41348.1 - 1.1e-101 338.9 0.1 1.4e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EJS41348.1 - 0.00098 18.7 0.0 0.0016 18.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EJS41348.1 - 0.01 16.3 0.1 0.056 13.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EJS41348.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EJS41348.1 - 0.027 15.0 0.0 0.05 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNase_H2-Ydr279 PF09468.5 EJS41348.1 - 0.042 13.0 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF226 PF02890.9 EJS41348.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 Methyltransf_30 PF05430.6 EJS41348.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Med1 PF10744.4 EJS41349.1 - 1.8e-78 264.0 18.1 7.4e-78 262.0 12.5 1.9 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Not3 PF04065.10 EJS41350.1 - 2.5e-80 269.1 39.0 2.1e-79 266.1 23.1 2.8 2 1 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EJS41350.1 - 4.7e-26 91.2 8.9 4.7e-26 91.2 6.1 3.8 4 1 0 4 4 4 1 NOT2 / NOT3 / NOT5 family NACHT PF05729.7 EJS41350.1 - 0.41 10.2 2.6 0.57 9.8 1.0 1.7 1 1 0 1 1 1 0 NACHT domain Ish1 PF10281.4 EJS41350.1 - 0.89 9.6 11.0 6.1 7.0 0.0 4.2 4 0 0 4 4 4 0 Putative stress-responsive nuclear envelope protein LMWPc PF01451.16 EJS41351.1 - 1.6e-44 151.6 0.0 1.8e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Transketolase_N PF00456.16 EJS41352.1 - 3.1e-158 525.9 0.0 7e-158 524.7 0.0 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EJS41352.1 - 4.6e-47 159.7 0.0 8.4e-47 158.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EJS41352.1 - 4.2e-15 55.7 0.0 1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EJS41352.1 - 3.2e-05 23.0 0.0 0.00033 19.6 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EJS41352.1 - 0.002 16.8 0.0 0.0045 15.7 0.0 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component Opy2 PF09463.5 EJS41353.1 - 1e-10 41.4 18.1 1.6e-10 40.8 12.5 1.3 1 0 0 1 1 1 1 Opy2 protein DUF2076 PF09849.4 EJS41353.1 - 0.00048 20.2 4.6 0.00048 20.2 3.2 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) LRR19-TM PF15176.1 EJS41353.1 - 0.004 16.8 3.3 0.051 13.2 0.1 2.8 2 1 0 2 2 2 1 Leucine-rich repeat family 19 TM domain DUF1510 PF07423.6 EJS41353.1 - 0.0063 15.9 0.0 0.0063 15.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Mid2 PF04478.7 EJS41353.1 - 0.022 14.1 7.5 0.048 13.0 0.1 3.4 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor DUF1049 PF06305.6 EJS41353.1 - 0.16 11.4 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) CENP-T PF15511.1 EJS41353.1 - 5.7 6.0 14.3 0.13 11.4 2.7 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T DUF619 PF04768.8 EJS41354.1 - 0.05 13.0 0.2 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF619) Syntaxin-6_N PF09177.6 EJS41354.1 - 0.1 12.9 1.3 1.1 9.7 0.4 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF2200 PF09966.4 EJS41354.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) CIMR PF00878.13 EJS41355.1 - 1.2e-09 38.0 0.9 5.8e-05 22.8 0.1 3.0 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 EJS41355.1 - 1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Man-6-P_recep PF02157.10 EJS41355.1 - 0.04 12.9 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor SRF-TF PF00319.13 EJS41356.1 - 8.4e-25 85.7 0.1 1.7e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ceramidase PF05875.7 EJS41357.1 - 6.1e-98 327.1 17.6 6.9e-98 326.9 12.2 1.0 1 0 0 1 1 1 1 Ceramidase DUF4231 PF14015.1 EJS41357.1 - 0.013 15.4 1.4 0.023 14.6 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2721 PF11026.3 EJS41357.1 - 2.3 7.8 6.0 4.4 6.9 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Radical_SAM PF04055.16 EJS41358.1 - 3.4e-15 56.6 0.5 8.4e-15 55.3 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EJS41358.1 - 1.4e-11 44.2 0.0 4.5e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family BRO1 PF03097.13 EJS41359.1 - 1.2e-97 327.0 9.3 2.7e-97 325.8 6.4 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EJS41359.1 - 6.5e-42 143.5 15.7 5.2e-41 140.5 10.9 2.3 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF2458 PF10454.4 EJS41359.1 - 0.33 10.8 7.7 1.2 9.0 5.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF3535 PF12054.3 EJS41360.1 - 3.4e-154 513.6 0.1 1.1e-153 512.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EJS41360.1 - 2.5e-78 262.9 0.0 4.3e-78 262.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EJS41360.1 - 9e-14 51.0 0.0 2.6e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EJS41360.1 - 7.7e-13 47.3 4.5 0.052 13.6 0.0 8.3 8 0 0 8 8 8 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EJS41360.1 - 2.7e-07 30.8 0.3 1.1 9.6 0.0 6.0 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EJS41360.1 - 0.0001 22.6 2.2 42 4.8 0.0 7.1 7 0 0 7 7 7 0 HEAT-like repeat Mt_ATP-synt_B PF05405.9 EJS41361.1 - 7.9e-56 188.0 8.8 1e-55 187.6 6.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SRX PF09201.5 EJS41361.1 - 0.003 17.2 1.3 0.0045 16.6 0.9 1.3 1 0 0 1 1 1 1 SRX AAA PF00004.24 EJS41363.1 - 3.6e-41 140.4 0.0 9.1e-41 139.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EJS41363.1 - 4.6e-05 23.5 0.4 0.0021 18.1 0.3 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EJS41363.1 - 4.8e-05 22.5 0.0 9.7e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EJS41363.1 - 0.00011 22.2 0.9 0.00024 21.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.5 EJS41363.1 - 0.00022 21.0 0.0 0.00074 19.3 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.1 EJS41363.1 - 0.00083 19.2 0.0 0.0052 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EJS41363.1 - 0.00092 19.5 6.3 0.0015 18.7 0.0 3.3 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 EJS41363.1 - 0.001 17.8 0.0 0.001 17.8 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 EJS41363.1 - 0.0019 17.6 0.2 0.0064 15.9 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 EJS41363.1 - 0.002 18.9 6.8 0.011 16.5 0.0 3.6 4 1 0 4 4 3 1 AAA domain AAA_5 PF07728.9 EJS41363.1 - 0.0026 17.5 0.0 0.015 15.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EJS41363.1 - 0.0027 16.8 0.1 0.0072 15.5 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EJS41363.1 - 0.0047 16.8 0.2 0.024 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EJS41363.1 - 0.0072 16.0 0.0 0.026 14.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EJS41363.1 - 0.0073 15.7 0.3 0.26 10.6 0.1 2.4 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EJS41363.1 - 0.0093 15.9 0.0 0.1 12.5 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 EJS41363.1 - 0.043 13.3 0.0 0.043 13.3 0.0 3.3 2 1 1 3 3 2 0 AAA domain VPS9 PF02204.13 EJS41365.1 - 4.2e-17 62.0 1.4 1.1e-16 60.7 1.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain polyprenyl_synt PF00348.12 EJS41366.1 - 5.2e-45 153.3 0.0 6.5e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3605 PF12239.3 EJS41368.1 - 2.3e-47 160.8 0.1 2.7e-47 160.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Arrestin_C PF02752.17 EJS41369.1 - 0.2 11.7 9.3 0.039 14.0 1.2 2.5 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain VPS28 PF03997.7 EJS41370.1 - 7.9e-79 263.6 3.3 9.3e-79 263.4 2.3 1.1 1 0 0 1 1 1 1 VPS28 protein DUF3114 PF11311.3 EJS41370.1 - 0.0015 17.9 0.6 0.024 14.0 0.2 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3114) DUF3417 PF11897.3 EJS41370.1 - 0.011 15.7 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) MipZ PF09140.6 EJS41370.1 - 0.061 12.3 0.2 0.11 11.5 0.1 1.5 1 1 0 1 1 1 0 ATPase MipZ DUF1759 PF03564.10 EJS41370.1 - 0.068 12.9 0.3 0.068 12.9 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) Pro_isomerase PF00160.16 EJS41371.1 - 3.9e-10 40.1 0.1 7.2e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aldedh PF00171.17 EJS41372.1 - 9.5e-173 574.7 0.0 1.1e-172 574.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FliD_C PF07195.7 EJS41372.1 - 0.024 13.9 0.1 0.049 12.9 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus ABC2_membrane PF01061.19 EJS41373.1 - 6.8e-69 231.2 50.1 2.2e-37 128.3 8.0 3.0 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EJS41373.1 - 1.7e-37 127.2 2.2 4.9e-30 103.2 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EJS41373.1 - 5.8e-36 123.8 0.0 2.3e-17 63.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EJS41373.1 - 2e-10 40.6 0.0 4.3e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EJS41373.1 - 3.3e-06 26.3 0.0 0.00025 20.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EJS41373.1 - 1.6e-05 24.4 0.0 0.016 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EJS41373.1 - 6.3e-05 22.3 0.0 0.39 9.9 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 EJS41373.1 - 9.1e-05 21.6 7.1 9.1e-05 21.6 4.9 3.0 2 2 0 2 2 2 1 ABC-2 family transporter protein cobW PF02492.14 EJS41373.1 - 0.00027 20.4 0.1 0.0011 18.3 0.1 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EJS41373.1 - 0.00031 20.2 0.2 0.015 14.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EJS41373.1 - 0.00073 20.3 0.0 0.017 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EJS41373.1 - 0.00089 19.4 0.0 0.037 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EJS41373.1 - 0.0018 17.9 0.7 0.017 14.7 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EJS41373.1 - 0.0019 18.2 1.6 0.0089 16.0 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain NACHT PF05729.7 EJS41373.1 - 0.0028 17.3 0.0 0.062 12.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 EJS41373.1 - 0.0032 17.7 0.0 0.15 12.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EJS41373.1 - 0.0049 16.8 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EJS41373.1 - 0.0052 16.7 0.0 0.078 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EJS41373.1 - 0.014 15.1 0.1 0.18 11.5 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 EJS41373.1 - 0.028 13.5 0.0 0.78 8.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 EJS41373.1 - 0.032 14.4 0.0 1.7 8.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 EJS41373.1 - 0.041 13.7 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EJS41373.1 - 0.066 13.7 0.0 18 5.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein SbcCD_C PF13558.1 EJS41373.1 - 0.076 12.9 0.1 3.3 7.7 0.0 3.2 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 EJS41373.1 - 0.098 12.3 0.0 14 5.3 0.0 3.2 3 0 0 3 3 3 0 NTPase Retinin_C PF04527.7 EJS41373.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Drosophila Retinin like protein AAA_10 PF12846.2 EJS41373.1 - 0.15 11.4 1.0 4.8 6.5 0.3 2.6 3 0 0 3 3 3 0 AAA-like domain AAA_30 PF13604.1 EJS41373.1 - 0.19 11.3 0.2 2.5 7.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EJS41373.1 - 0.22 11.0 0.4 1.2 8.6 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EJS41373.1 - 0.33 10.7 0.6 17 5.2 0.0 3.1 3 0 0 3 3 3 0 Dynamin family Gly_transf_sug PF04488.10 EJS41374.1 - 5.1e-23 81.4 0.0 1.2e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EJS41374.1 - 0.0041 15.6 5.1 0.099 11.1 0.4 2.9 3 0 0 3 3 3 2 TcdA/TcdB catalytic glycosyltransferase domain Lge1 PF11488.3 EJS41375.1 - 3.4e-17 62.4 1.1 7.5e-17 61.3 0.7 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 zf-CCCH PF00642.19 EJS41376.1 - 2.2e-11 43.1 10.4 6.3e-06 25.7 2.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EJS41376.1 - 0.00065 19.5 16.4 0.063 13.3 2.8 2.9 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type LRV_FeS PF05484.6 EJS41376.1 - 0.13 11.8 0.8 6.3 6.4 0.1 2.4 2 0 0 2 2 2 0 LRV protein FeS4 cluster Glyco_transf_15 PF01793.11 EJS41377.1 - 1.1e-103 346.7 10.9 1.3e-103 346.4 7.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ODC_AZ PF02100.12 EJS41378.1 - 0.00065 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Arf PF00025.16 EJS41379.1 - 5.2e-47 159.3 0.4 6.3e-47 159.0 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EJS41379.1 - 1.9e-15 56.6 0.0 2.3e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EJS41379.1 - 7.4e-13 48.0 0.1 9e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EJS41379.1 - 5.8e-12 46.1 0.0 8.9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EJS41379.1 - 1.3e-09 37.7 0.0 5.6e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EJS41379.1 - 4.7e-09 35.4 1.0 7.4e-05 21.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EJS41379.1 - 1.4e-07 30.8 0.1 1.8e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EJS41379.1 - 4.1e-07 29.9 0.0 6.4e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EJS41379.1 - 0.026 14.6 0.0 0.083 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EJS41379.1 - 0.041 14.1 0.8 0.13 12.6 0.5 1.9 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EJS41379.1 - 0.065 12.6 0.1 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_18 PF13238.1 EJS41379.1 - 0.075 13.3 0.7 0.41 10.9 0.5 2.1 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EJS41379.1 - 0.13 11.6 0.1 1.9 7.9 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EF1G PF00647.14 EJS41381.1 - 9.4e-48 160.3 0.2 1.7e-47 159.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EJS41381.1 - 5.5e-12 45.5 0.0 1.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EJS41381.1 - 2e-11 43.8 0.1 6.1e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EJS41381.1 - 1.5e-07 31.2 0.1 3.1e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sgf11 PF08209.6 EJS41382.1 - 8.3e-16 57.0 3.8 1.1e-15 56.6 2.7 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EJS41382.1 - 0.00056 19.4 0.2 0.00076 19.0 0.2 1.2 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.3 EJS41382.1 - 0.084 12.3 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Skp1_POZ PF03931.10 EJS41383.1 - 1.8e-16 59.9 0.2 3.4e-16 59.0 0.0 1.5 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EJS41383.1 - 0.001 19.0 0.1 0.0036 17.2 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain Vps16_N PF04841.8 EJS41384.1 - 2.7e-122 408.2 0.3 4.8e-122 407.4 0.2 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EJS41384.1 - 2.8e-110 368.2 11.0 5e-110 367.3 7.6 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region RRM_1 PF00076.17 EJS41385.1 - 2.5e-55 184.0 1.1 1e-18 66.7 0.2 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS41385.1 - 1.4e-44 149.8 0.5 3.1e-12 46.2 0.1 5.1 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS41385.1 - 5.7e-18 64.5 1.1 2.3e-07 30.5 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 EJS41385.1 - 0.0015 16.7 1.1 0.0015 16.7 0.8 2.7 3 0 0 3 3 3 1 CDC45-like protein HIF-1a_CTAD PF08778.5 EJS41385.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Pkinase PF00069.20 EJS41386.1 - 2.8e-53 180.7 1.5 2e-51 174.6 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41386.1 - 1.5e-24 86.4 0.4 1.1e-23 83.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase tRNA-synt_1 PF00133.17 EJS41387.1 - 4.5e-153 510.4 0.1 6.2e-153 509.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EJS41387.1 - 8.4e-23 80.6 4.1 2.5e-13 49.4 0.0 4.3 5 0 0 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EJS41387.1 - 4.9e-21 75.0 1.0 9.7e-21 74.1 0.2 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 EJS41387.1 - 0.012 15.1 2.8 0.03 13.9 1.9 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-C2H2 PF00096.21 EJS41388.1 - 6.8e-09 35.5 10.5 0.00043 20.4 0.9 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS41388.1 - 3.1e-08 33.3 4.8 0.0026 17.9 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger C1_4 PF07975.7 EJS41388.1 - 0.00013 21.8 0.8 0.0064 16.4 0.0 2.2 2 0 0 2 2 2 1 TFIIH C1-like domain zf-H2C2_2 PF13465.1 EJS41388.1 - 0.00021 21.3 3.1 0.0028 17.8 0.1 2.8 3 0 0 3 3 3 1 Zinc-finger double domain SprT-like PF10263.4 EJS41388.1 - 0.041 13.5 1.5 0.056 13.0 1.0 1.4 1 1 0 1 1 1 0 SprT-like family zf-H2C2_5 PF13909.1 EJS41388.1 - 0.046 13.9 1.4 0.046 13.9 0.9 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EJS41388.1 - 0.12 12.5 3.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.16 EJS41388.1 - 0.32 10.9 6.9 1.1 9.1 4.8 1.8 1 1 0 1 1 1 0 FYVE zinc finger HypA PF01155.14 EJS41388.1 - 0.39 10.4 2.4 0.66 9.6 0.1 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C2H2_3 PF13878.1 EJS41388.1 - 0.43 10.1 5.3 0.19 11.3 0.5 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_6 PF13912.1 EJS41388.1 - 0.46 10.4 7.8 4.4 7.3 0.9 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger RIG-I_C-RD PF11648.3 EJS41388.1 - 0.55 10.1 3.0 2.9 7.7 2.1 2.1 1 1 2 3 3 3 0 C-terminal domain of RIG-I LIM PF00412.17 EJS41388.1 - 0.67 10.0 3.6 5.6 7.1 0.2 2.3 1 1 0 2 2 2 0 LIM domain OrfB_Zn_ribbon PF07282.6 EJS41388.1 - 1.3 8.7 4.4 19 4.9 0.6 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_ribbon_recom PF13408.1 EJS41388.1 - 3.2 8.0 6.7 3.1 8.1 1.1 2.4 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain BCMA-Tall_bind PF09257.5 EJS41388.1 - 4.7 7.2 5.6 4.8 7.2 0.1 3.0 4 0 0 4 4 4 0 BCMA, TALL-1 binding NAC PF01849.13 EJS41389.1 - 5.4e-17 61.0 0.1 1e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 NAC domain Ribosomal_60s PF00428.14 EJS41389.1 - 0.016 15.5 2.6 0.19 12.1 0.2 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_hydro_20b PF02838.10 EJS41389.1 - 0.028 14.9 0.2 0.073 13.6 0.1 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 RNA_GG_bind PF10258.4 EJS41389.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 PHAX RNA-binding domain adh_short PF00106.20 EJS41390.1 - 0.097 12.5 0.0 0.35 10.7 0.0 1.8 1 1 0 1 1 1 0 short chain dehydrogenase RRM_6 PF14259.1 EJS41391.1 - 3.4e-12 46.1 0.0 5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EJS41391.1 - 1.8e-11 43.5 0.0 2.8e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS41391.1 - 2.3e-10 40.1 0.0 3.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox_KN PF05920.6 EJS41392.1 - 2.5e-18 65.4 1.0 5.9e-18 64.2 0.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EJS41392.1 - 5.9e-06 25.8 0.8 1.3e-05 24.6 0.5 1.6 1 0 0 1 1 1 1 Homeobox domain TFR_dimer PF04253.10 EJS41393.1 - 2.5e-26 91.7 0.0 5e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EJS41393.1 - 0.00034 20.2 0.0 0.0081 15.8 0.0 2.4 2 0 0 2 2 2 1 PA domain UbiA PF01040.13 EJS41394.1 - 1.5e-21 76.7 12.6 2e-21 76.3 8.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Oxidored_FMN PF00724.15 EJS41395.1 - 1.3e-126 422.2 0.0 1.5e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2414 PF10309.4 EJS41395.1 - 0.034 13.8 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Cyt-b5 PF00173.23 EJS41396.1 - 1.2e-14 53.8 0.0 1.8e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TAP_C PF03943.8 EJS41397.1 - 3.7e-20 71.0 0.4 1.1e-19 69.5 0.0 2.0 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.2 EJS41397.1 - 1.3e-06 27.8 10.7 1.3e-05 24.6 0.9 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EJS41397.1 - 1.6e-05 24.5 0.6 2.9e-05 23.6 0.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 EJS41397.1 - 0.0044 16.9 3.4 0.87 9.8 0.1 3.9 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.28 EJS41397.1 - 0.89 9.8 7.6 1.2e+02 3.3 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat DNA_pol_B PF00136.16 EJS41398.1 - 1.1e-97 327.7 1.0 2.2e-97 326.7 0.7 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EJS41398.1 - 1.8e-18 66.5 4.3 3.4e-09 35.9 0.8 2.7 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EJS41398.1 - 6.6e-13 48.4 9.2 1.8e-12 47.1 6.3 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Spectrin PF00435.16 EJS41398.1 - 0.029 14.6 1.2 0.13 12.5 0.8 2.1 1 0 0 1 1 1 0 Spectrin repeat SET PF00856.23 EJS41399.1 - 8.2e-11 42.4 0.1 3.8e-09 37.0 0.1 2.2 2 0 0 2 2 2 2 SET domain DUF3661 PF12400.3 EJS41400.1 - 6.1e-45 152.4 7.6 1.1e-44 151.6 5.3 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein Ribosomal_60s PF00428.14 EJS41401.1 - 0.029 14.7 0.2 0.062 13.6 0.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein tRNA-synt_1 PF00133.17 EJS41402.1 - 1.1e-42 145.8 0.0 2.1e-34 118.5 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EJS41402.1 - 4.3e-20 71.7 0.8 2e-10 39.8 0.0 4.2 4 0 0 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EJS41402.1 - 2.2e-13 50.2 0.0 6.8e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EJS41402.1 - 1.1e-06 27.9 0.0 2.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Methyltransf_15 PF09445.5 EJS41403.1 - 1.4e-62 210.0 0.0 2.1e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EJS41403.1 - 4.5e-10 39.3 0.0 6.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EJS41403.1 - 1.4e-09 38.0 0.0 2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EJS41403.1 - 1.2e-07 31.3 0.0 1.9e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS41403.1 - 2.4e-07 31.3 0.0 4.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EJS41403.1 - 3.9e-05 23.9 0.0 7.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EJS41403.1 - 0.0076 15.7 0.1 0.61 9.5 0.0 2.3 1 1 1 2 2 2 2 DNA methylase Cons_hypoth95 PF03602.10 EJS41403.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MethyltransfD12 PF02086.10 EJS41403.1 - 0.025 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_23 PF13489.1 EJS41403.1 - 0.026 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EJS41403.1 - 0.057 12.4 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF4640 PF15480.1 EJS41404.1 - 0.2 11.1 2.8 0.12 11.9 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4640) Asp PF00026.18 EJS41405.1 - 1.1e-106 356.6 0.0 1.3e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EJS41405.1 - 6.6e-11 42.4 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EJS41405.1 - 4.8e-05 23.7 0.0 0.024 15.1 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EJS41405.1 - 0.034 13.6 0.0 0.21 11.1 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Pkinase PF00069.20 EJS41406.1 - 1.9e-79 266.5 0.0 3.7e-79 265.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41406.1 - 7.5e-38 130.0 0.0 1.5e-37 129.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EJS41406.1 - 2.7e-28 97.8 1.0 9.9e-16 57.6 0.1 2.8 2 0 0 2 2 2 2 FHA domain Kinase-like PF14531.1 EJS41406.1 - 2.4e-07 30.0 0.0 4.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EJS41406.1 - 3.7e-05 22.8 0.0 8e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS41406.1 - 0.00041 20.1 0.0 0.016 14.9 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EJS41406.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family PTPA PF03095.10 EJS41407.1 - 8.1e-116 386.3 0.5 9.3e-116 386.1 0.4 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein WD40 PF00400.27 EJS41408.1 - 1e-46 155.1 17.3 4e-08 32.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EJS41408.1 - 5.3e-06 24.8 5.9 0.055 11.6 0.0 4.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EJS41408.1 - 0.0016 17.9 0.3 1.2 8.5 0.1 2.6 2 0 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EJS41408.1 - 0.0033 16.2 0.8 2.7 6.6 0.1 4.0 1 1 3 4 4 4 2 Nup133 N terminal like ACPS PF01648.15 EJS41409.1 - 3.2e-18 65.6 0.0 5.3e-18 64.9 0.0 1.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ABC_membrane_2 PF06472.10 EJS41410.1 - 2.7e-93 312.1 5.0 2.7e-93 312.1 3.5 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EJS41410.1 - 5.4e-15 55.9 0.0 1.8e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EJS41410.1 - 0.00052 19.3 0.2 0.53 9.4 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EJS41410.1 - 0.0084 16.1 0.2 0.031 14.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 EJS41410.1 - 2.5 8.3 13.7 2.2 8.5 6.6 2.7 2 1 0 2 2 2 0 AAA domain Nop53 PF07767.6 EJS41411.1 - 4.7e-82 276.0 42.5 6.3e-82 275.6 29.5 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) SlyX PF04102.7 EJS41411.1 - 0.57 10.5 5.5 16 5.9 0.7 3.3 3 0 0 3 3 3 0 SlyX Oxysterol_BP PF01237.13 EJS41412.1 - 1.1e-93 313.5 1.0 1.3e-93 313.3 0.7 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Pkinase PF00069.20 EJS41413.1 - 1.2e-65 221.3 0.0 4.2e-65 219.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41413.1 - 2.4e-37 128.3 0.0 4.4e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS41413.1 - 1.6e-07 30.6 0.0 3.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EJS41413.1 - 0.009 15.3 0.1 0.023 14.0 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EJS41413.1 - 0.0097 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EJS41413.1 - 0.029 13.4 0.1 0.08 11.9 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.24 EJS41414.1 - 1.3e-11 43.9 5.0 1.3e-11 43.9 3.4 2.6 3 0 0 3 3 3 1 PHD-finger DUF1383 PF07134.6 EJS41414.1 - 0.019 13.8 2.0 0.038 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1383) DUF4047 PF13256.1 EJS41414.1 - 1.2 9.0 5.9 0.36 10.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Sds3 PF08598.6 EJS41414.1 - 9.4 5.7 9.6 0.13 11.8 0.3 2.3 2 1 0 3 3 3 0 Sds3-like LRR_4 PF12799.2 EJS41415.1 - 0.0062 16.1 19.9 0.74 9.5 0.1 5.3 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EJS41415.1 - 4.4 7.6 12.4 45 4.5 0.0 5.6 5 0 0 5 5 5 0 Leucine Rich repeat NifU_N PF01592.11 EJS41416.1 - 1.3e-54 183.5 0.0 1.6e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Zn_clus PF00172.13 EJS41417.1 - 0.0011 18.8 11.2 0.0026 17.6 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CtaG_Cox11 PF04442.9 EJS41418.1 - 1.7e-58 196.7 0.0 2.7e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF1891 PF09004.5 EJS41418.1 - 0.041 13.2 1.4 0.088 12.2 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) Ribosomal_L18p PF00861.17 EJS41419.1 - 2.6e-46 156.7 0.0 2.6e-46 156.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EJS41419.1 - 2.3e-32 111.3 1.3 2.3e-32 111.3 0.9 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EJS41419.1 - 0.016 15.2 0.3 0.97 9.5 0.0 2.8 3 0 0 3 3 3 0 Threonine synthase N terminus Imm24 PF15570.1 EJS41420.1 - 0.025 14.3 4.7 0.045 13.4 3.2 1.4 1 1 0 1 1 1 0 Immunity protein 24 TRF PF08558.5 EJS41421.1 - 4e-83 278.4 0.4 5.8e-83 277.8 0.3 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EJS41421.1 - 1.5e-08 34.5 0.4 3.3e-08 33.4 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EJS41421.1 - 0.001 19.1 0.1 0.0031 17.5 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Linker_histone PF00538.14 EJS41422.1 - 3.1e-47 158.5 13.5 1.2e-24 86.2 0.1 3.4 4 0 0 4 4 4 2 linker histone H1 and H5 family Dicty_REP PF05086.7 EJS41422.1 - 2 6.1 13.4 0.035 11.8 2.6 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 EJS41423.1 - 6.8e-08 32.1 6.8 0.00011 21.8 0.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Fib_alpha PF08702.5 EJS41424.1 - 0.19 11.8 1.0 0.77 9.8 0.0 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ribonuclease_T2 PF00445.13 EJS41425.1 - 9.8e-43 145.9 1.1 1.6e-42 145.3 0.7 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Tfb2 PF03849.9 EJS41426.1 - 1.2e-156 520.9 3.4 1.2e-156 520.9 2.4 1.5 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EJS41426.1 - 1.8e-05 24.5 0.1 7.3e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Mei5 PF10376.4 EJS41427.1 - 4.8e-49 166.8 20.8 5.5e-49 166.6 14.4 1.0 1 0 0 1 1 1 1 Double-strand recombination repair protein Cortex-I_coil PF09304.5 EJS41427.1 - 0.41 10.7 24.2 0.03 14.3 5.0 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil Mt_ATP-synt_D PF05873.7 EJS41427.1 - 1.3 8.6 5.6 0.21 11.1 0.7 1.8 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) APG6 PF04111.7 EJS41428.1 - 8e-101 337.2 18.5 8e-101 337.2 12.8 2.2 2 0 0 2 2 2 1 Autophagy protein Apg6 Mit_ribos_Mrp51 PF11709.3 EJS41429.1 - 1.1e-92 310.5 0.2 1.3e-92 310.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Borrelia_lipo_1 PF05714.6 EJS41429.1 - 0.019 14.1 2.0 0.062 12.3 1.4 1.8 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein NUDIX PF00293.23 EJS41430.1 - 5.9e-29 100.4 0.0 8.7e-29 99.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Hist_deacetyl PF00850.14 EJS41431.1 - 6.6e-63 212.8 0.1 1.2e-62 212.0 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RhoGAP PF00620.22 EJS41432.1 - 3.7e-37 127.2 3.7 9.7e-37 125.9 0.1 2.8 3 0 0 3 3 3 1 RhoGAP domain PX PF00787.19 EJS41432.1 - 2.7e-09 36.8 0.0 9.1e-09 35.1 0.0 2.0 1 0 0 1 1 1 1 PX domain PH PF00169.24 EJS41432.1 - 8.8e-07 29.0 1.1 2e-06 27.9 0.1 2.3 2 0 0 2 2 2 1 PH domain DUF1708 PF08101.6 EJS41432.1 - 0.0013 17.6 0.0 0.0025 16.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) 2-Hacid_dh_C PF02826.14 EJS41433.1 - 6.7e-34 116.5 0.0 1.3e-33 115.6 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EJS41433.1 - 0.0036 16.7 0.0 0.0087 15.5 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EJS41433.1 - 0.029 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EJS41433.1 - 0.068 12.6 0.1 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 EJS41433.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain PEX11 PF05648.9 EJS41434.1 - 1.5e-08 34.2 4.6 2e-06 27.2 1.6 2.4 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) IFN-gamma PF00714.12 EJS41434.1 - 0.022 14.5 2.8 0.078 12.8 1.9 2.0 1 1 0 1 1 1 0 Interferon gamma Arginase PF00491.16 EJS41435.1 - 2.5e-74 250.0 0.0 2.9e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family GDPD PF03009.12 EJS41436.1 - 3.5e-88 295.4 0.1 6.4e-88 294.5 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EJS41436.1 - 5.4e-35 119.5 7.1 6.5e-12 45.6 0.1 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) SPX PF03105.14 EJS41436.1 - 3.7e-31 108.9 9.2 3.7e-31 108.9 6.4 2.6 2 1 0 2 2 2 1 SPX domain Ank PF00023.25 EJS41436.1 - 1.3e-19 68.8 1.2 0.0031 17.2 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EJS41436.1 - 5.1e-18 65.0 2.6 1.9e-06 28.2 0.2 5.6 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EJS41436.1 - 4.9e-11 42.4 0.5 0.032 14.4 0.0 5.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EJS41436.1 - 4.8e-10 38.6 9.4 2.3 8.7 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Oxidored-like PF09791.4 EJS41437.1 - 7.3e-27 92.5 3.7 1.4e-26 91.6 2.5 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal ATPase-cat_bd PF12156.3 EJS41437.1 - 0.079 13.4 0.2 0.2 12.2 0.0 1.8 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase HSP70 PF00012.15 EJS41438.1 - 3.5e-197 656.0 3.8 3.5e-197 656.0 2.7 2.2 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EJS41438.1 - 3.2e-11 42.3 0.1 1.3e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EJS41438.1 - 2.6e-05 24.0 2.8 0.00098 18.9 0.5 3.7 2 2 0 2 2 2 1 Cell division protein FtsA Trans_reg_C PF00486.23 EJS41438.1 - 0.054 13.4 0.3 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal GYF PF02213.11 EJS41439.1 - 3e-20 71.5 0.2 6.7e-20 70.4 0.1 1.6 1 0 0 1 1 1 1 GYF domain DUF4339 PF14237.1 EJS41439.1 - 0.022 14.3 0.2 0.07 12.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) tRNA-synt_2 PF00152.15 EJS41440.1 - 1.7e-115 385.4 0.3 2.2e-115 385.0 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EJS41440.1 - 7.9e-06 25.6 0.1 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EJS41440.1 - 5.4e-05 22.8 0.0 0.007 15.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EJS41440.1 - 0.0014 17.8 0.4 0.026 13.6 0.1 2.7 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) Lactamase_B_2 PF12706.2 EJS41441.1 - 1e-32 113.2 0.0 1.5e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EJS41441.1 - 2.4e-11 43.6 0.0 7.9e-11 41.9 0.0 1.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain PAXNEB PF05625.6 EJS41442.1 - 2.6e-109 365.4 2.0 3.2e-109 365.1 1.4 1.0 1 0 0 1 1 1 1 PAXNEB protein SieB PF14163.1 EJS41443.1 - 0.0018 17.8 0.6 0.071 12.6 0.0 2.2 2 0 0 2 2 2 2 Superinfection exclusion protein B DUF607 PF04678.8 EJS41443.1 - 0.11 12.4 0.5 0.23 11.3 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Romo1 PF10247.4 EJS41444.1 - 6.5e-28 96.7 7.9 8.2e-28 96.4 5.5 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 tRNA-synt_1b PF00579.20 EJS41445.1 - 1.3e-81 273.9 0.0 1.6e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PgaD PF13994.1 EJS41446.1 - 0.097 12.1 2.7 0.12 11.8 1.9 1.3 1 1 0 1 1 1 0 PgaD-like protein PrgI PF12666.2 EJS41446.1 - 0.19 11.8 0.8 0.2 11.8 0.6 1.0 1 0 0 1 1 1 0 PrgI family protein Pkr1 PF08636.5 EJS41446.1 - 0.51 10.4 5.8 0.6 10.2 4.0 1.2 1 0 0 1 1 1 0 ER protein Pkr1 Rad4 PF03835.10 EJS41447.1 - 3.3e-12 46.0 0.3 6.9e-12 44.9 0.2 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EJS41447.1 - 1e-08 35.3 0.0 2.4e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Desulfoferrod_N PF06397.7 EJS41447.1 - 0.04 13.2 0.6 0.04 13.2 0.4 1.9 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Zn_Tnp_IS1595 PF12760.2 EJS41447.1 - 1.1 9.1 6.1 3 7.7 4.3 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Abhydrolase_1 PF00561.15 EJS41448.1 - 2.1e-27 96.1 0.0 2.9e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EJS41448.1 - 4.1e-15 56.2 0.0 6.7e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EJS41448.1 - 5.9e-10 39.0 0.0 3.2e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EJS41448.1 - 0.0062 15.7 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF915 PF06028.6 EJS41448.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) ORC3_N PF07034.6 EJS41448.1 - 0.088 11.7 0.0 0.19 10.6 0.0 1.5 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus PAF-AH_p_II PF03403.8 EJS41448.1 - 0.095 10.9 0.1 9.5 4.3 0.0 2.2 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.9 EJS41448.1 - 0.13 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) NOG1 PF06858.9 EJS41449.1 - 1.9e-27 94.8 0.4 4.7e-27 93.6 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EJS41449.1 - 1.9e-27 94.7 1.3 1.9e-27 94.7 0.9 1.8 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EJS41449.1 - 1e-15 57.6 0.0 2.8e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EJS41449.1 - 1.3e-07 30.9 0.0 3e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EJS41449.1 - 0.00029 20.0 0.1 0.00073 18.7 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EJS41449.1 - 0.0046 17.4 0.1 0.018 15.5 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EJS41449.1 - 0.017 14.9 0.2 10 5.8 0.0 3.1 2 1 1 3 3 3 0 Dynamin family SLAC1 PF03595.12 EJS41450.1 - 2e-85 286.3 29.5 2.3e-85 286.1 20.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Pyr_redox_2 PF07992.9 EJS41451.1 - 2.8e-40 138.3 0.5 4.7e-40 137.6 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EJS41451.1 - 1.1e-36 125.1 0.5 1.3e-35 121.6 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EJS41451.1 - 3e-19 69.1 7.4 5.3e-18 65.1 1.1 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EJS41451.1 - 6e-10 39.5 0.2 1.4e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EJS41451.1 - 5.5e-08 32.3 0.1 1.6e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EJS41451.1 - 2.4e-06 26.7 0.0 4.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EJS41451.1 - 6.7e-06 25.7 0.1 0.0014 18.2 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EJS41451.1 - 1.3e-05 23.9 7.8 0.027 12.9 0.4 3.8 2 1 2 4 4 4 2 HI0933-like protein GIDA PF01134.17 EJS41451.1 - 9.6e-05 21.4 0.4 9.6e-05 21.4 0.3 3.2 2 1 1 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 EJS41451.1 - 0.00021 20.2 0.5 0.00021 20.2 0.4 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EJS41451.1 - 0.00044 19.9 3.1 0.0018 17.9 0.1 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EJS41451.1 - 0.00087 18.4 0.5 1 8.4 0.0 3.1 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EJS41451.1 - 0.0034 17.6 0.2 1.5 9.0 0.0 2.8 3 0 0 3 3 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EJS41451.1 - 0.0078 15.2 1.1 1.8 7.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EJS41451.1 - 0.0097 15.0 1.3 0.03 13.4 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EJS41451.1 - 0.03 14.3 0.5 0.03 14.3 0.3 2.1 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 EJS41451.1 - 0.049 13.0 0.2 0.1 12.0 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EJS41451.1 - 0.062 13.0 1.3 0.55 9.9 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CPSase_L_chain PF00289.17 EJS41451.1 - 0.11 12.5 0.1 1.7 8.8 0.0 2.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain FAD_binding_2 PF00890.19 EJS41451.1 - 5.5 5.7 12.7 0.034 12.9 1.6 2.5 4 0 0 4 4 4 0 FAD binding domain DUF663 PF04950.7 EJS41452.1 - 3.3e-106 354.5 0.3 3.3e-106 354.5 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EJS41452.1 - 2.5e-28 97.4 0.0 6.7e-28 96.0 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EJS41452.1 - 9.2e-08 31.7 0.0 3.2e-05 23.4 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EJS41452.1 - 8.8e-06 26.5 0.0 8.8e-06 26.5 0.0 3.6 3 1 0 4 4 3 1 AAA domain AAA PF00004.24 EJS41452.1 - 1.6e-05 25.1 0.0 4.5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EJS41452.1 - 2.7e-05 24.0 0.0 0.00022 21.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EJS41452.1 - 7.5e-05 22.4 0.1 0.00026 20.7 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EJS41452.1 - 0.00019 21.5 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 EJS41452.1 - 0.00041 20.8 0.9 0.0023 18.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 EJS41452.1 - 0.00047 19.8 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EJS41452.1 - 0.00096 19.3 0.0 0.0027 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EJS41452.1 - 0.0015 18.2 0.3 0.0052 16.4 0.2 1.9 1 1 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 EJS41452.1 - 0.0026 17.7 0.0 0.009 15.9 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EJS41452.1 - 0.0026 18.0 0.0 0.0026 18.0 0.0 4.4 4 2 0 4 4 2 1 AAA domain AAA_28 PF13521.1 EJS41452.1 - 0.0053 16.7 0.1 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EJS41452.1 - 0.007 16.5 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 EJS41452.1 - 0.0093 15.3 0.0 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EJS41452.1 - 0.016 14.6 0.2 0.033 13.6 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EJS41452.1 - 0.017 15.4 0.0 0.017 15.4 0.0 2.4 3 0 0 3 3 1 0 ABC transporter PduV-EutP PF10662.4 EJS41452.1 - 0.022 14.2 0.1 0.44 10.0 0.0 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 EJS41452.1 - 0.022 14.3 0.0 0.022 14.3 0.0 3.4 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 EJS41452.1 - 0.029 14.1 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 EJS41452.1 - 0.099 12.1 0.1 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Ubiq_cyt_C_chap PF03981.7 EJS41453.1 - 3e-41 140.5 0.2 5.4e-41 139.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HK PF02110.10 EJS41454.1 - 6.7e-96 320.2 0.1 1.1e-95 319.4 0.1 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EJS41454.1 - 1e-57 194.2 0.0 1.4e-57 193.6 0.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI ShlB PF03865.8 EJS41454.1 - 0.069 11.8 0.1 0.18 10.4 0.1 1.6 1 1 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB LRR_9 PF14580.1 EJS41455.1 - 2.4e-11 43.5 0.7 3.7e-11 42.9 0.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EJS41455.1 - 0.00061 19.3 16.0 0.0019 17.7 1.1 4.6 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EJS41455.1 - 2.3 8.5 9.4 12 6.2 0.2 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.1 EJS41455.1 - 2.4 7.9 12.9 4.6 7.0 4.3 3.6 1 1 3 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 EJS41455.1 - 2.8 8.3 14.7 14 6.2 0.4 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 EJS41455.1 - 4.3 7.9 10.7 40 5.0 0.1 5.2 5 1 0 5 5 5 0 Leucine rich repeat UPF0113 PF03657.8 EJS41456.1 - 1.6e-13 50.6 0.0 1.9e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) SRP72 PF08492.7 EJS41457.1 - 1.4e-14 54.1 4.7 1.4e-14 54.1 3.3 2.5 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_12 PF13424.1 EJS41457.1 - 1.5e-06 28.0 5.4 0.00053 19.8 0.1 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EJS41457.1 - 2.2e-06 27.1 10.5 0.0096 15.7 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EJS41457.1 - 2.3e-05 24.6 3.0 0.0023 18.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EJS41457.1 - 5.4e-05 22.7 2.8 0.013 15.0 0.0 3.8 4 0 0 4 4 4 1 TPR repeat Apc3 PF12895.2 EJS41457.1 - 0.002 18.2 13.1 0.97 9.6 0.5 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EJS41457.1 - 0.012 16.1 0.2 17 6.3 0.0 4.4 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EJS41457.1 - 0.18 11.4 0.2 0.18 11.4 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EJS41457.1 - 0.22 11.4 5.9 2 8.3 0.0 4.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EJS41457.1 - 0.32 10.9 3.4 13 5.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EJS41457.1 - 1.2 9.7 5.7 64 4.3 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EJS41457.1 - 9.5 6.2 9.7 0.45 10.4 0.1 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EJS41458.1 - 1.7e-72 243.6 0.1 2.2e-72 243.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41458.1 - 4e-46 157.2 0.0 5.3e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS41458.1 - 1.9e-06 27.0 0.0 2.8e-05 23.2 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EJS41458.1 - 0.0084 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EJS41458.1 - 0.1 11.9 0.3 0.24 10.7 0.2 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EJS41458.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family SET PF00856.23 EJS41459.1 - 0.0012 19.1 0.1 0.0023 18.2 0.1 1.5 1 0 0 1 1 1 1 SET domain Radical_SAM PF04055.16 EJS41460.1 - 1e-23 84.3 0.0 2.3e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EJS41460.1 - 2.7e-20 72.2 0.0 6.7e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EJS41460.1 - 1.6e-13 50.9 0.0 3.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Guanylate_kin PF00625.16 EJS41460.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase GDPD PF03009.12 EJS41461.1 - 4.3e-41 141.1 0.0 5.1e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EJS41461.1 - 0.00057 19.9 0.1 0.013 15.6 0.0 2.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF3132 PF11330.3 EJS41461.1 - 0.07 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) Pkinase PF00069.20 EJS41462.1 - 1.8e-41 141.9 0.0 3.5e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41462.1 - 7.4e-14 51.4 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EJS41462.1 - 0.0051 16.5 0.5 0.084 12.5 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family PAT1 PF09770.4 EJS41462.1 - 6.8 4.7 33.3 8.7 4.4 23.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 EJS41463.1 - 1.9e-70 237.0 0.3 2.9e-70 236.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41463.1 - 2.1e-40 138.4 0.0 3.5e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS41463.1 - 9.7e-06 24.7 0.2 2.3e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EJS41463.1 - 0.038 13.3 2.2 0.14 11.4 0.0 2.6 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL APH PF01636.18 EJS41463.1 - 0.048 13.3 0.2 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EJS41463.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4557 PF15101.1 EJS41463.1 - 0.33 10.7 8.1 2 8.2 6.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF3387 PF11867.3 EJS41465.1 - 0.051 12.5 1.4 0.066 12.1 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Uds1 PF15456.1 EJS41465.1 - 0.078 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Fib_alpha PF08702.5 EJS41465.1 - 0.1 12.7 0.4 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family THP2 PF09432.5 EJS41465.1 - 1.6 8.5 7.3 1.3 8.8 1.2 2.3 1 1 1 2 2 2 0 Tho complex subunit THP2 DUF1771 PF08590.5 EJS41466.1 - 8.9e-22 76.8 8.6 1.5e-21 76.1 5.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EJS41466.1 - 3.6e-16 59.1 0.2 6.8e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Smr domain DUF1625 PF07787.7 EJS41466.1 - 0.054 12.7 1.1 0.075 12.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) GET2 PF08690.5 EJS41466.1 - 0.15 11.3 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 GET complex subunit GET2 TLD PF07534.11 EJS41467.1 - 3.2e-28 98.4 0.1 1e-27 96.8 0.1 1.8 1 1 0 1 1 1 1 TLD Rad9 PF04139.8 EJS41468.1 - 1.6e-10 40.5 0.5 4.1e-05 22.8 0.1 2.4 2 0 0 2 2 2 2 Rad9 DUF4412 PF14371.1 EJS41468.1 - 0.0013 19.2 0.5 0.0092 16.4 0.1 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4412) NUFIP1 PF10453.4 EJS41469.1 - 2.2e-17 62.3 0.4 5.9e-17 60.9 0.3 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) APC_CDC26 PF10471.4 EJS41469.1 - 0.0093 16.6 0.6 0.0093 16.6 0.4 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex APC subunit 1 DUF544 PF04424.8 EJS41470.1 - 1e-32 112.5 0.5 2.2e-32 111.3 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF544) IncA PF04156.9 EJS41470.1 - 0.62 9.6 6.3 1.1 8.8 4.4 1.3 1 0 0 1 1 1 0 IncA protein RRM_1 PF00076.17 EJS41471.1 - 3.2e-11 42.7 0.1 9.1e-11 41.2 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS41471.1 - 9.3e-09 35.1 0.0 2.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS41471.1 - 0.00025 20.8 0.1 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MBOAT PF03062.14 EJS41472.1 - 2.2e-71 240.6 25.6 2.2e-71 240.6 17.8 2.1 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family NAD_kinase PF01513.16 EJS41473.1 - 2.8e-51 174.0 0.0 3.6e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EJS41473.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Glyco_hydro_10 PF00331.15 EJS41473.1 - 0.16 10.9 0.1 0.5 9.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 DUF4407 PF14362.1 EJS41474.1 - 0.44 9.4 7.3 0.62 8.9 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L36 PF00444.13 EJS41475.1 - 4.6e-20 71.3 8.3 6.1e-20 70.9 5.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 EJS41475.1 - 0.0059 15.8 0.9 0.0083 15.4 0.6 1.2 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family WD40 PF00400.27 EJS41476.1 - 1.7e-22 78.4 25.8 1.4e-08 34.2 0.1 9.8 11 0 0 11 11 11 5 WD domain, G-beta repeat Nup160 PF11715.3 EJS41476.1 - 0.00069 17.8 2.7 0.2 9.7 0.1 3.5 3 1 0 3 3 3 2 Nucleoporin Nup120/160 YmzC PF14157.1 EJS41476.1 - 0.044 13.5 0.1 11 5.9 0.0 2.8 2 0 0 2 2 2 0 YmzC-like protein PHD PF00628.24 EJS41477.1 - 5.3e-12 45.2 8.6 9.2e-12 44.4 6.0 1.4 1 0 0 1 1 1 1 PHD-finger MCLC PF05934.6 EJS41477.1 - 1.7 6.8 10.8 3.5 5.8 7.5 1.6 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) TCO89 PF10452.4 EJS41478.1 - 1.1e-211 704.9 59.0 1.1e-211 704.9 40.9 1.4 2 0 0 2 2 2 1 TORC1 subunit TCO89 Metallophos PF00149.23 EJS41479.1 - 2.4e-41 141.3 0.1 4e-41 140.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_2 PF12796.2 EJS41480.1 - 5.7e-24 84.2 0.9 1.9e-15 56.9 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EJS41480.1 - 2.2e-16 59.8 0.3 5.5e-11 42.6 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EJS41480.1 - 1.3e-15 57.0 0.4 1.8e-08 34.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EJS41480.1 - 1.8e-15 55.8 0.2 1.9e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EJS41480.1 - 4.7e-12 44.8 0.1 0.00012 21.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat PqqD PF05402.7 EJS41480.1 - 0.022 14.7 1.1 12 6.0 0.0 3.3 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) XPA_N PF01286.13 EJS41480.1 - 0.17 11.5 1.5 9.9 5.9 0.0 2.5 3 0 0 3 3 3 0 XPA protein N-terminal eIF-5_eIF-2B PF01873.12 EJS41481.1 - 3.7e-46 155.8 0.1 5.9e-46 155.1 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.10 EJS41481.1 - 0.00069 19.2 0.1 0.018 14.6 0.0 2.9 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region TF_Zn_Ribbon PF08271.7 EJS41481.1 - 0.078 12.3 0.2 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Pkinase PF00069.20 EJS41482.1 - 6.2e-37 127.1 0.0 3.2e-36 124.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41482.1 - 6e-18 64.8 0.0 1.5e-17 63.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase WHIM3 PF15614.1 EJS41482.1 - 0.16 11.8 0.1 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 TIP49 PF06068.8 EJS41483.1 - 5.9e-180 598.1 4.0 7.2e-180 597.9 2.8 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EJS41483.1 - 9.2e-09 35.5 0.7 1.5e-05 25.2 0.1 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EJS41483.1 - 4.5e-07 29.1 2.9 0.0004 19.5 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EJS41483.1 - 1.3e-05 24.1 0.1 3.2e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EJS41483.1 - 6e-05 23.1 0.0 0.00065 19.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EJS41483.1 - 9.7e-05 22.5 1.7 0.078 13.1 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.9 EJS41483.1 - 0.012 15.3 0.2 3.3 7.4 0.0 2.9 2 2 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EJS41483.1 - 0.016 14.3 0.7 0.37 9.9 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EJS41483.1 - 0.018 14.7 0.2 0.041 13.6 0.2 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EJS41483.1 - 0.037 13.4 0.8 0.08 12.3 0.2 1.8 2 0 0 2 2 2 0 AAA domain Sipho_tail PF05709.6 EJS41483.1 - 0.053 12.6 0.1 0.1 11.7 0.1 1.5 1 0 0 1 1 1 0 Phage tail protein Sigma54_activat PF00158.21 EJS41483.1 - 0.053 12.9 0.0 8.5 5.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 EJS41483.1 - 0.065 13.1 0.1 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain CBFD_NFYB_HMF PF00808.18 EJS41483.1 - 0.089 12.8 0.2 0.31 11.1 0.2 2.0 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ATP-synt_C PF00137.16 EJS41484.1 - 3.2e-28 97.3 26.3 5.9e-15 54.9 2.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 EJS41484.1 - 0.19 11.1 7.7 0.02 14.3 1.7 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Mis14 PF08641.7 EJS41485.1 - 1.3e-37 128.9 8.8 1.3e-37 128.9 6.1 1.9 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Gemini_AL1_M PF08283.6 EJS41485.1 - 0.0059 16.4 0.4 0.024 14.4 0.2 2.1 1 1 0 1 1 1 1 Geminivirus rep protein central domain GreA_GreB_N PF03449.10 EJS41485.1 - 0.045 13.8 0.2 0.045 13.8 0.2 2.4 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal DUF4298 PF14131.1 EJS41485.1 - 1.7 8.5 7.6 13 5.7 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) DivIVA PF05103.8 EJS41485.1 - 5.5 7.0 10.9 0.35 10.9 1.3 2.7 2 1 1 3 3 3 0 DivIVA protein SNARE PF05739.14 EJS41486.1 - 1.3e-16 60.0 5.6 4.2e-16 58.3 3.9 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EJS41486.1 - 2.1e-07 31.0 4.6 2.1e-07 31.0 3.2 2.3 2 0 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 EJS41486.1 - 6e-05 22.5 1.8 6e-05 22.5 1.3 2.3 2 0 0 2 2 2 1 Synaptobrevin Rifin_STEVOR PF02009.11 EJS41486.1 - 0.0013 18.4 3.5 0.0013 18.4 2.5 1.6 1 1 1 2 2 2 1 Rifin/stevor family Baculo_PEP_C PF04513.7 EJS41486.1 - 0.0054 16.5 3.4 0.17 11.7 0.1 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus T2SF PF00482.18 EJS41486.1 - 0.007 16.2 0.1 0.02 14.7 0.1 1.7 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F BLOC1_2 PF10046.4 EJS41486.1 - 0.025 14.7 5.3 2.2 8.4 0.1 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EJS41486.1 - 0.028 13.6 2.1 2.1 7.4 0.1 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein AATase PF07247.7 EJS41486.1 - 0.057 11.9 5.6 0.082 11.4 0.8 2.1 2 0 0 2 2 2 0 Alcohol acetyltransferase DUF3753 PF12575.3 EJS41486.1 - 0.075 12.8 0.4 0.075 12.8 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Lsr2 PF11774.3 EJS41486.1 - 0.11 12.4 4.2 0.21 11.5 0.8 2.5 2 0 0 2 2 2 0 Lsr2 Allexi_40kDa PF05549.6 EJS41486.1 - 0.12 11.7 6.7 0.18 11.0 0.5 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein 7tm_7 PF08395.7 EJS41486.1 - 0.3 10.0 1.4 3.4 6.5 0.1 2.7 3 0 0 3 3 3 0 7tm Chemosensory receptor DUF4094 PF13334.1 EJS41486.1 - 0.32 11.4 0.2 0.32 11.4 0.1 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4094) DUF2562 PF10814.3 EJS41486.1 - 0.97 9.3 3.6 0.81 9.6 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2562) DASH_Dam1 PF08653.5 EJS41486.1 - 1.3 8.8 3.4 8.8 6.1 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF3708 PF12501.3 EJS41486.1 - 1.8 8.4 6.1 3.2 7.5 1.1 2.4 1 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter GP41 PF00517.12 EJS41486.1 - 2.8 7.4 8.5 0.95 8.9 0.3 3.2 2 2 1 3 3 3 0 Retroviral envelope protein Nipped-B_C PF12830.2 EJS41486.1 - 3.9 7.0 8.3 0.56 9.8 2.3 1.8 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus PBP1_TM PF14812.1 EJS41486.1 - 4.1 7.7 8.0 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 EJS41486.1 - 5.7 7.0 8.0 0.33 11.0 0.3 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2116 PF09889.4 EJS41486.1 - 6.4 6.6 5.9 1.4 8.7 0.8 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) adh_short_C2 PF13561.1 EJS41487.1 - 2.2e-20 73.4 0.1 4.8e-19 69.0 0.0 2.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 EJS41487.1 - 3.4e-19 69.3 0.0 6.2e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EJS41487.1 - 1.4e-16 60.3 0.0 3.5e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EJS41487.1 - 1.6e-12 47.3 0.0 8.4e-12 44.9 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EJS41487.1 - 2.8e-06 27.3 0.1 1.4e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EJS41487.1 - 0.0015 18.2 0.1 0.0056 16.3 0.0 2.0 2 0 0 2 2 2 1 KR domain mRNA_triPase PF02940.10 EJS41489.1 - 1.3e-59 201.5 0.3 1.3e-59 201.5 0.2 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Glycos_transf_2 PF00535.21 EJS41490.1 - 4.4e-25 88.3 0.0 6e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EJS41490.1 - 1.9e-06 27.8 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EJS41490.1 - 0.00054 19.1 0.0 0.00073 18.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EJS41490.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 ABC_tran PF00005.22 EJS41491.1 - 8e-48 162.2 0.0 8e-25 87.7 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EJS41491.1 - 8.4e-15 55.4 4.8 4.4e-05 23.5 0.0 4.2 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 EJS41491.1 - 6.1e-13 48.5 0.0 0.00062 19.0 0.0 3.5 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EJS41491.1 - 4.1e-09 35.9 1.2 8.9e-09 34.8 0.8 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 EJS41491.1 - 2.1e-07 30.3 0.1 0.015 14.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EJS41491.1 - 3.2e-06 26.4 0.0 0.016 14.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EJS41491.1 - 7e-06 26.8 0.9 0.065 14.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EJS41491.1 - 7.8e-06 26.0 0.0 0.078 13.1 0.0 3.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EJS41491.1 - 9e-06 25.6 0.0 0.11 12.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EJS41491.1 - 9.2e-06 25.3 2.3 0.73 9.2 0.0 4.6 5 0 0 5 5 5 2 AAA-like domain RNA_helicase PF00910.17 EJS41491.1 - 0.0003 20.9 0.1 3.5 7.8 0.0 3.6 3 0 0 3 3 3 2 RNA helicase Miro PF08477.8 EJS41491.1 - 0.00039 20.9 0.0 1.4 9.4 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 EJS41491.1 - 0.00039 20.3 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EJS41491.1 - 0.00053 20.3 13.9 0.03 14.6 0.0 4.2 5 0 0 5 5 4 2 AAA domain SbcCD_C PF13558.1 EJS41491.1 - 0.00077 19.3 0.4 1.9 8.4 0.0 3.7 2 2 1 3 3 3 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EJS41491.1 - 0.00088 18.1 0.5 0.79 8.4 0.0 2.7 3 0 0 3 3 3 2 ArgK protein MobB PF03205.9 EJS41491.1 - 0.0015 18.2 0.0 0.89 9.2 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EJS41491.1 - 0.0018 18.5 0.3 1.5 9.1 0.1 3.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EJS41491.1 - 0.0029 17.2 0.8 3 7.3 0.2 3.4 3 1 0 3 3 2 1 AAA domain NACHT PF05729.7 EJS41491.1 - 0.0032 17.1 0.0 0.83 9.2 0.0 3.0 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 EJS41491.1 - 0.0039 17.1 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EJS41491.1 - 0.0043 17.2 0.0 3.9 7.6 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EJS41491.1 - 0.0094 15.7 3.5 0.72 9.6 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 EJS41491.1 - 0.011 15.5 0.0 3.3 7.5 0.0 3.5 2 1 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 EJS41491.1 - 0.013 14.5 0.3 12 4.9 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.1 EJS41491.1 - 0.021 14.8 0.2 1.9 8.4 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain Thymidylate_kin PF02223.12 EJS41491.1 - 0.054 12.8 0.2 0.81 9.0 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase Polysacc_synt_4 PF04669.8 EJS41492.1 - 6.4e-22 77.8 1.7 4.5e-21 75.0 1.2 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis YcbB PF08664.5 EJS41492.1 - 0.027 14.2 0.3 0.042 13.6 0.2 1.3 1 0 0 1 1 1 0 YcbB domain RAP1 PF07218.6 EJS41493.1 - 9.6 4.1 5.9 1.1 7.2 1.4 1.4 1 1 1 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) UPF0061 PF02696.9 EJS41494.1 - 3.2e-216 718.3 0.1 3.7e-216 718.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family E2_bind PF08825.5 EJS41494.1 - 0.086 12.6 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 E2 binding domain SAGA-Tad1 PF12767.2 EJS41495.1 - 2.8e-77 259.8 0.1 4e-77 259.3 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 EJS41495.1 - 0.00058 19.2 0.0 0.00085 18.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF2630 PF10944.3 EJS41496.1 - 1 9.4 7.6 6 7.0 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) Reo_sigmaC PF04582.7 EJS41496.1 - 2.8 7.0 11.6 2.8 7.0 5.0 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF1843 PF08898.5 EJS41496.1 - 8.1 6.5 8.7 1.8 8.6 0.5 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Fungal_trans PF04082.13 EJS41498.1 - 1.1e-27 96.6 9.2 2.8e-27 95.2 6.4 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 EJS41498.1 - 2.2e-11 43.4 1.5 6.4e-11 42.0 1.0 1.8 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.13 EJS41498.1 - 5.4e-08 32.6 18.9 8.8e-08 31.9 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EJS41499.1 - 1e-17 63.2 15.0 2.9e-07 30.1 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Rhomboid PF01694.17 EJS41500.1 - 5.9e-23 81.5 9.1 5.9e-23 81.5 6.3 1.5 2 0 0 2 2 2 1 Rhomboid family DUF2075 PF09848.4 EJS41501.1 - 1.5e-105 353.1 0.0 1.7e-105 352.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EJS41501.1 - 2.1e-07 31.1 0.0 7.1e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EJS41501.1 - 0.00031 20.9 0.0 0.00063 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EJS41501.1 - 0.00089 19.1 0.0 0.13 12.1 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EJS41501.1 - 0.00093 19.2 0.0 0.0016 18.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EJS41501.1 - 0.0025 17.9 0.2 0.42 10.8 0.0 3.2 2 1 1 3 3 3 1 RNA helicase VirE PF05272.6 EJS41501.1 - 0.0025 17.2 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 Virulence-associated protein E MMR_HSR1 PF01926.18 EJS41501.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.1 EJS41501.1 - 0.0062 16.1 0.1 0.049 13.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EJS41501.1 - 0.01 16.1 0.7 0.46 10.8 0.0 3.1 4 0 0 4 4 4 0 AAA domain Bac_DnaA PF00308.13 EJS41501.1 - 0.015 14.9 0.4 0.29 10.7 0.3 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein NACHT PF05729.7 EJS41501.1 - 0.022 14.4 0.1 0.056 13.0 0.0 1.9 2 1 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 EJS41501.1 - 0.031 14.1 0.1 0.099 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EJS41501.1 - 0.032 13.1 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.9 EJS41501.1 - 0.055 12.4 0.0 0.15 10.9 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase Viral_helicase1 PF01443.13 EJS41501.1 - 0.098 12.1 0.0 0.32 10.4 0.0 1.9 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 EJS41501.1 - 0.098 11.8 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zds_C PF08632.5 EJS41501.1 - 0.1 12.0 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term AAA_19 PF13245.1 EJS41501.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain UAA PF08449.6 EJS41502.1 - 2.7e-92 308.9 16.7 3.1e-92 308.7 11.5 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EJS41502.1 - 3.4e-08 33.5 23.4 1e-06 28.8 7.8 3.0 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 EJS41502.1 - 2.1e-07 30.6 10.1 2.1e-07 30.6 7.0 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EJS41502.1 - 0.00016 20.8 9.0 0.043 12.9 5.0 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EJS41502.1 - 0.0014 18.7 24.4 0.0077 16.4 8.1 3.1 3 1 0 3 3 3 2 Multidrug resistance efflux transporter UPF0546 PF10639.4 EJS41502.1 - 2.8 7.7 10.4 9.9 6.0 2.6 2.6 2 1 0 2 2 2 0 Uncharacterised protein family UPF0546 DNA_Packaging_2 PF11123.3 EJS41503.1 - 0.042 13.7 1.5 0.14 12.0 0.1 2.5 2 0 0 2 2 2 0 DNA packaging protein ATP-synt_Eps PF04627.8 EJS41504.1 - 9.3e-18 63.5 2.7 1.1e-17 63.3 1.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PI-PLC-X PF00388.14 EJS41505.1 - 1.5e-49 167.1 1.2 2.8e-49 166.2 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EJS41505.1 - 4.6e-38 129.8 0.0 1.5e-37 128.1 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.1 EJS41505.1 - 7.6e-06 25.9 2.1 4.5e-05 23.4 0.6 2.9 3 0 0 3 3 3 1 EF-hand domain pair C2 PF00168.25 EJS41505.1 - 0.00042 20.0 0.1 0.0018 18.0 0.0 2.1 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.27 EJS41505.1 - 0.0011 18.1 2.3 0.0054 15.9 0.2 2.8 2 0 0 2 2 2 1 EF hand EF-hand_like PF09279.6 EJS41505.1 - 0.046 13.7 0.6 0.24 11.4 0.4 2.2 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 EJS41505.1 - 0.077 12.6 2.7 0.11 12.2 0.9 2.1 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 EJS41505.1 - 0.15 11.7 2.3 0.29 10.7 0.2 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 EJS41505.1 - 1.1 9.3 4.5 1.7 8.7 0.3 3.4 4 0 0 4 4 4 0 EF-hand domain RrnaAD PF00398.15 EJS41507.1 - 2.9e-69 233.0 0.0 3.4e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EJS41507.1 - 3.8e-11 43.0 0.0 5.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS41507.1 - 5.1e-06 27.0 0.0 8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EJS41507.1 - 7.2e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.7 EJS41507.1 - 8e-05 23.0 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EJS41507.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EJS41507.1 - 0.00014 21.2 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EJS41507.1 - 0.00081 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EJS41507.1 - 0.0011 18.1 0.0 0.0024 16.9 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EJS41507.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EJS41507.1 - 0.003 16.7 0.1 0.014 14.5 0.0 2.0 3 0 0 3 3 3 1 O-methyltransferase Methyltransf_12 PF08242.7 EJS41507.1 - 0.0072 16.7 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EJS41507.1 - 0.076 12.1 0.1 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.11 EJS41507.1 - 0.077 11.9 0.2 0.46 9.3 0.0 1.9 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase UPF0020 PF01170.13 EJS41507.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 UPF0158 PF03682.8 EJS41507.1 - 0.12 12.0 0.4 0.22 11.1 0.1 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) AA_permease PF00324.16 EJS41508.1 - 6.3e-120 400.7 42.7 7.7e-120 400.4 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS41508.1 - 3.1e-34 118.2 44.7 3.9e-34 117.9 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease NDUF_C2 PF06374.6 EJS41508.1 - 0.039 13.9 2.5 0.65 10.0 0.1 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) EamA PF00892.15 EJS41509.1 - 4.5e-26 91.3 27.3 1e-14 54.6 5.5 2.6 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EJS41509.1 - 2.8e-08 33.9 5.0 2.8e-08 33.9 3.5 3.7 2 1 2 4 4 4 1 Multidrug resistance efflux transporter UAA PF08449.6 EJS41509.1 - 0.00057 18.8 18.6 0.0047 15.8 13.3 2.1 1 1 0 1 1 1 1 UAA transporter family Kelch_3 PF13415.1 EJS41510.1 - 3.5e-31 106.6 1.5 2.7e-09 36.9 0.0 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EJS41510.1 - 8.3e-28 95.9 7.2 1.3e-06 28.0 0.1 7.0 5 2 1 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.1 EJS41510.1 - 2.1e-22 78.7 0.4 2.1e-22 78.7 0.3 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 EJS41510.1 - 1.7e-18 65.9 9.8 1.1e-05 25.4 0.1 6.4 4 2 2 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EJS41510.1 - 1.9e-14 53.2 5.2 0.00032 20.5 0.1 6.2 6 1 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EJS41510.1 - 1.5e-13 50.0 11.8 6.3e-05 22.4 0.1 6.4 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.10 EJS41510.1 - 8.7e-12 44.3 8.6 0.0002 21.0 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Lyase_1 PF00206.15 EJS41511.1 - 4.4e-120 400.5 0.0 6.8e-120 399.9 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EJS41511.1 - 4e-25 87.6 0.0 9.8e-25 86.3 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 EJS41511.1 - 0.022 14.5 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF2408 PF10303.4 EJS41512.1 - 1.1e-78 261.8 21.1 2.5e-51 173.3 3.2 5.0 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) MtrG PF04210.8 EJS41512.1 - 0.092 12.4 1.5 2.9 7.6 0.0 3.3 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Adap_comp_sub PF00928.16 EJS41513.1 - 1.1e-88 296.8 0.5 1.4e-88 296.4 0.3 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EJS41513.1 - 1.4e-08 34.5 0.3 2.6e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Phos_pyr_kin PF08543.7 EJS41514.1 - 1.5e-79 266.6 0.6 1.9e-79 266.3 0.4 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EJS41514.1 - 2e-65 220.4 0.1 2.8e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EJS41514.1 - 2.8e-05 23.4 0.0 4.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 EJS41514.1 - 0.053 12.7 0.2 0.1 11.8 0.1 1.6 1 1 0 1 1 1 0 Carbohydrate kinase Synaptobrevin PF00957.16 EJS41516.1 - 7.1e-32 108.8 1.7 8.1e-32 108.6 1.1 1.0 1 0 0 1 1 1 1 Synaptobrevin ODV-E18 PF10717.4 EJS41516.1 - 0.66 9.4 4.0 1.1 8.7 0.3 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF912 PF06024.7 EJS41516.1 - 2.5 8.2 5.6 7.6 6.6 3.8 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ABC2_membrane PF01061.19 EJS41517.1 - 2.4e-84 281.7 60.0 8.4e-43 145.9 16.4 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EJS41517.1 - 1.3e-36 125.9 0.0 6.3e-18 65.3 0.0 3.0 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EJS41517.1 - 7.6e-34 115.4 11.0 2.8e-33 113.6 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EJS41517.1 - 1.6e-21 76.1 0.1 3.7e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EJS41517.1 - 1.8e-08 34.0 0.0 0.00012 21.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EJS41517.1 - 1.4e-06 28.4 2.0 1.2e-05 25.3 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 EJS41517.1 - 6.7e-05 22.7 0.0 0.012 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EJS41517.1 - 0.00018 21.9 0.1 0.03 14.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EJS41517.1 - 0.00032 19.9 0.0 0.0046 16.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EJS41517.1 - 0.00037 19.9 0.6 0.0043 16.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EJS41517.1 - 0.0004 19.8 1.0 0.085 12.2 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EJS41517.1 - 0.00074 19.2 0.5 0.63 9.8 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 EJS41517.1 - 0.002 18.4 0.0 0.049 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EJS41517.1 - 0.0026 17.9 0.2 0.24 11.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EJS41517.1 - 0.0028 18.4 0.0 0.14 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EJS41517.1 - 0.004 17.1 0.0 0.041 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EJS41517.1 - 0.0081 15.4 0.0 1.1 8.4 0.0 2.7 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EJS41517.1 - 0.012 15.5 2.0 0.13 12.2 0.3 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EJS41517.1 - 0.013 15.1 2.0 1.8 8.1 0.1 2.9 3 0 0 3 3 3 0 NACHT domain UPF0079 PF02367.12 EJS41517.1 - 0.019 14.6 0.5 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 EJS41517.1 - 0.11 12.9 0.0 5.4 7.5 0.0 3.1 3 0 0 3 3 3 0 Miro-like protein AAA_30 PF13604.1 EJS41517.1 - 0.13 11.8 0.4 4.2 6.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 EJS41517.1 - 0.65 8.9 45.4 0.0048 15.9 5.4 3.5 2 1 1 3 3 3 0 ABC-2 family transporter protein vATP-synt_E PF01991.13 EJS41519.1 - 7e-64 214.7 17.2 8.2e-64 214.5 11.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phlebovirus_NSM PF07246.6 EJS41519.1 - 0.11 11.6 10.6 0.02 14.0 5.0 1.4 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M CorA PF01544.13 EJS41520.1 - 2.3e-05 23.5 8.4 5.9e-05 22.2 5.8 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Leptin PF02024.10 EJS41520.1 - 0.004 16.8 0.5 0.011 15.4 0.3 1.7 1 0 0 1 1 1 1 Leptin Ala_racemase_N PF01168.15 EJS41520.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain tRNA-synt_2c PF01411.14 EJS41521.1 - 8.8e-228 757.0 0.1 1.6e-227 756.2 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EJS41521.1 - 1.6e-18 66.2 0.1 4.2e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EJS41521.1 - 1.1e-08 34.6 1.3 3.1e-08 33.1 0.9 1.9 1 0 0 1 1 1 1 DHHA1 domain UDP-g_GGTase PF06427.6 EJS41522.1 - 1.5e-08 34.2 0.3 1.4e-07 31.0 0.1 2.4 1 1 1 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Strep_67kDa_ant PF06100.6 EJS41522.1 - 0.014 13.8 0.6 0.022 13.1 0.4 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family PDZ PF00595.19 EJS41522.1 - 0.036 14.2 0.5 0.85 9.8 0.0 3.0 3 0 0 3 3 3 0 PDZ domain (Also known as DHR or GLGF) DUF2458 PF10454.4 EJS41522.1 - 0.037 13.9 0.1 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Fungal_trans PF04082.13 EJS41523.1 - 6.6e-37 126.7 6.0 1.9e-36 125.3 2.6 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS41523.1 - 5.2e-08 32.6 8.5 8.8e-08 31.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 EJS41523.1 - 0.008 14.5 4.1 0.015 13.6 2.8 1.3 1 0 0 1 1 1 1 Transmembrane protein SWIRM PF04433.12 EJS41524.1 - 4.7e-12 45.8 0.0 9.9e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain UQ_con PF00179.21 EJS41525.1 - 1.9e-49 166.6 0.1 2.2e-49 166.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EJS41525.1 - 0.0015 18.2 0.5 0.0023 17.6 0.4 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EJS41525.1 - 0.0027 17.5 0.2 0.0045 16.8 0.1 1.6 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EJS41525.1 - 0.0064 16.2 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B SHS2_Rpb7-N PF03876.12 EJS41526.1 - 9.5e-14 51.2 0.0 2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rpb1_5 PF04998.12 EJS41527.1 - 5e-102 340.8 3.0 1.9e-100 335.6 0.3 3.2 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EJS41527.1 - 1.1e-64 217.4 0.2 1.1e-64 217.4 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EJS41527.1 - 3.2e-38 130.9 0.0 2.9e-37 127.8 0.0 2.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EJS41527.1 - 1e-23 83.1 2.7 2.6e-23 81.8 0.0 3.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 EJS41527.1 - 1.2e-20 74.1 2.1 1.2e-20 74.1 1.5 4.3 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 HLH PF00010.21 EJS41529.1 - 5.7e-23 80.3 0.7 1.4e-22 79.0 0.1 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain IMS PF00817.15 EJS41530.1 - 4.2e-27 94.7 0.0 8.8e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family BRCT PF00533.21 EJS41530.1 - 5.4e-13 48.8 0.2 2.4e-12 46.8 0.1 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_C PF11799.3 EJS41530.1 - 3e-09 36.8 0.0 8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.2 EJS41530.1 - 1e-06 28.4 0.1 2.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF4414 PF14377.1 EJS41530.1 - 0.00039 20.2 4.2 0.0097 15.8 3.2 3.0 3 1 1 4 4 4 1 Domain of unknown function (DUF4414) PK PF00224.16 EJS41531.1 - 5.1e-154 512.0 0.2 6.5e-154 511.7 0.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EJS41531.1 - 4.5e-28 97.1 0.0 1.4e-27 95.5 0.0 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EJS41531.1 - 0.00015 20.7 0.5 0.00035 19.5 0.0 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family AA_permease PF00324.16 EJS41532.1 - 1e-146 489.0 39.9 1.2e-146 488.8 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS41532.1 - 5.9e-25 87.6 43.8 8.9e-25 87.0 30.4 1.2 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 EJS41534.1 - 1e-68 231.2 0.0 1.4e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41534.1 - 5.4e-30 104.3 0.0 7.7e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EJS41534.1 - 4.1e-16 58.8 0.1 1.3e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EJS41534.1 - 2.2e-06 26.8 0.0 3.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EJS41534.1 - 0.0015 17.6 0.0 0.0035 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS41534.1 - 0.042 13.5 0.1 2.2 7.9 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SOG2 PF10428.4 EJS41536.1 - 2.1e-131 438.6 16.5 3.2e-131 438.0 11.4 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein LRR_4 PF12799.2 EJS41536.1 - 3.3e-18 64.8 25.6 3e-09 36.2 0.3 4.8 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EJS41536.1 - 1.1e-17 63.5 11.2 5.3e-13 48.5 1.5 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EJS41536.1 - 2.6e-12 44.9 9.3 0.17 11.9 0.0 6.9 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 EJS41536.1 - 1e-06 27.9 7.4 1.3 9.4 0.0 6.4 5 0 0 5 5 5 3 Leucine rich repeat SpecificRecomb PF10136.4 EJS41536.1 - 0.004 15.2 0.3 0.0076 14.3 0.2 1.3 1 0 0 1 1 1 1 Site-specific recombinase LRR_6 PF13516.1 EJS41536.1 - 0.0081 16.1 12.6 1.7 8.9 0.0 6.3 6 1 1 7 7 7 1 Leucine Rich repeat DUF313 PF03754.8 EJS41537.1 - 0.012 15.5 1.1 10 6.1 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF313) ETF_QO PF05187.8 EJS41538.1 - 2.4e-39 133.7 0.0 5.1e-39 132.6 0.0 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EJS41538.1 - 6.1e-12 45.1 0.1 6.2e-06 25.3 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 EJS41538.1 - 1.6e-08 33.9 0.1 9e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 EJS41538.1 - 2.6e-07 29.8 2.3 0.011 14.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EJS41538.1 - 1.8e-06 27.9 0.2 4.1e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EJS41538.1 - 5.2e-06 25.8 0.0 7.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EJS41538.1 - 0.0043 16.8 0.2 0.011 15.5 0.1 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EJS41538.1 - 0.0058 16.5 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 EJS41538.1 - 0.0062 16.9 0.6 0.017 15.4 0.4 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_binding_3 PF01494.14 EJS41538.1 - 0.0074 15.3 0.2 0.013 14.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EJS41538.1 - 0.029 12.8 0.7 0.071 11.5 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EJS41538.1 - 0.049 13.6 0.3 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EJS41538.1 - 0.051 13.9 2.1 1.7 9.0 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EJS41538.1 - 0.45 9.0 1.6 1.1 7.8 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase PX PF00787.19 EJS41539.1 - 9.6e-24 83.3 0.2 1.2e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 PX domain CBFD_NFYB_HMF PF00808.18 EJS41540.1 - 8.2e-20 70.6 2.0 1.4e-19 69.9 1.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EJS41540.1 - 3.5e-17 62.3 0.3 5.8e-17 61.5 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EJS41540.1 - 0.17 11.6 0.2 0.17 11.6 0.1 1.9 2 0 0 2 2 2 0 CENP-S associating Centromere protein X PBP1_TM PF14812.1 EJS41540.1 - 3.5 8.0 8.3 14 6.0 0.5 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 EJS41540.1 - 7.8 6.8 15.7 2.6 8.3 2.3 2.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain SAM_2 PF07647.12 EJS41541.1 - 4.3e-09 36.0 0.4 1.2e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EJS41541.1 - 0.00025 21.1 0.1 0.00054 20.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.14 EJS41542.1 - 5.7e-65 219.3 4.4 9.9e-65 218.5 3.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EJS41542.1 - 0.0057 16.6 0.3 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 HD domain Proteasome PF00227.21 EJS41543.1 - 4.2e-53 179.4 0.0 5.5e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EJS41543.1 - 7.7e-12 44.3 0.9 9.9e-12 43.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn_clus PF00172.13 EJS41544.1 - 9e-10 38.3 9.4 2.2e-09 37.0 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRP PF06011.7 EJS41545.1 - 3.9e-128 427.7 43.2 4.7e-128 427.4 29.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EJS41545.1 - 5.3e-38 130.2 0.3 8.5e-38 129.5 0.2 1.3 1 0 0 1 1 1 1 ML-like domain CH PF00307.26 EJS41546.1 - 2.2e-12 46.9 0.1 3.2e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 EJS41546.1 - 0.0065 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin Rad1 PF02144.11 EJS41547.1 - 1.4e-68 230.6 2.8 1.8e-68 230.3 1.9 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ribosomal_L7Ae PF01248.21 EJS41548.1 - 8e-23 79.7 0.3 1e-22 79.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 EJS41548.1 - 0.12 12.3 0.9 0.37 10.8 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) GDI PF00996.13 EJS41549.1 - 7.9e-58 195.8 0.0 1.4e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor NTR2 PF15458.1 EJS41549.1 - 0.85 8.8 2.3 1.4 8.0 1.6 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Kelch_3 PF13415.1 EJS41550.1 - 9.7e-08 31.9 0.9 0.0092 16.1 0.0 4.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EJS41550.1 - 3.3e-07 30.1 2.3 0.1 12.8 0.0 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.1 EJS41550.1 - 5e-07 29.3 12.1 0.0079 15.9 0.6 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EJS41550.1 - 8.9e-05 22.0 3.5 1.2 8.9 0.7 5.0 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 EJS41550.1 - 0.0002 21.2 0.5 1.5 8.8 0.0 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 EJS41550.1 - 1.4 8.5 13.9 3 7.4 1.1 4.5 5 0 0 5 5 5 0 Kelch motif Aldedh PF00171.17 EJS41552.1 - 6.9e-183 608.1 0.2 7.8e-183 608.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EJS41552.1 - 0.00027 19.7 0.0 0.00082 18.2 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EJS41552.1 - 0.023 13.9 0.1 5.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ELFV_dehydrog PF00208.16 EJS41553.1 - 4.7e-84 281.7 2.5 5.8e-84 281.4 1.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EJS41553.1 - 1.9e-45 153.6 0.0 3.7e-45 152.7 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EJS41553.1 - 0.11 12.7 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AATase PF07247.7 EJS41554.1 - 7.5e-165 549.0 0.0 8.6e-165 548.8 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase DUF724 PF05266.9 EJS41554.1 - 0.058 13.0 0.1 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Linker_histone PF00538.14 EJS41554.1 - 0.14 12.2 0.6 4.7 7.3 0.0 2.9 3 0 0 3 3 3 0 linker histone H1 and H5 family Fungal_trans PF04082.13 EJS41555.1 - 6.2e-20 71.1 0.1 9.3e-20 70.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS41555.1 - 1.6e-08 34.3 6.8 2.9e-08 33.4 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_6 PF08030.7 EJS41556.1 - 5e-28 97.9 0.0 8.6e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EJS41556.1 - 8e-28 96.3 0.0 1.5e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EJS41556.1 - 1.4e-21 76.8 9.7 1.4e-21 76.8 6.7 3.2 3 1 1 4 4 4 1 Ferric reductase like transmembrane component PRESAN PF09687.5 EJS41556.1 - 0.045 13.8 1.8 0.097 12.7 1.2 1.5 1 0 0 1 1 1 0 Plasmodium RESA N-terminal FAD_binding_6 PF00970.19 EJS41556.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Ribosomal_60s PF00428.14 EJS41557.1 - 1.6 9.1 6.0 0.59 10.5 1.6 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein SR-25 PF10500.4 EJS41557.1 - 2.7 7.4 11.9 3.4 7.0 8.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Golgin_A5 PF09787.4 EJS41557.1 - 8.5 4.7 11.0 10 4.5 7.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 FAM196 PF15265.1 EJS41558.1 - 5.5 6.0 14.7 6.9 5.7 10.2 1.0 1 0 0 1 1 1 0 FAM196 family FAD_binding_8 PF08022.7 EJS41559.1 - 1.7e-27 95.3 0.1 3.3e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EJS41559.1 - 3.5e-25 88.7 0.0 5.6e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EJS41559.1 - 9.4e-18 64.4 14.1 9.4e-18 64.4 9.7 2.7 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EJS41559.1 - 0.00039 20.9 0.0 0.012 16.1 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_7 PF03441.9 EJS41560.1 - 1.1e-79 267.5 0.4 2.6e-79 266.3 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EJS41560.1 - 3.8e-24 85.2 0.1 9.6e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 DNA photolyase MFS_1 PF07690.11 EJS41561.1 - 2.6e-26 92.1 57.8 7.2e-26 90.7 35.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EJS41561.1 - 3.1e-13 48.8 24.5 4.4e-11 41.6 17.1 2.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2407_C PF13373.1 EJS41562.1 - 3.2e-49 166.4 2.2 4.9e-49 165.8 1.5 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EJS41562.1 - 3.5e-22 78.3 0.0 8.5e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Acetyltransf_11 PF13720.1 EJS41562.1 - 0.015 15.5 0.3 0.045 13.9 0.0 1.9 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 RNA_pol_Rpb8 PF03870.10 EJS41563.1 - 7.4e-50 168.7 0.0 8.3e-50 168.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NifU_N PF01592.11 EJS41564.1 - 9.7e-53 177.4 0.1 1.1e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain LRR_8 PF13855.1 EJS41565.1 - 0.048 13.4 7.6 0.065 12.9 0.2 4.3 4 0 0 4 4 4 0 Leucine rich repeat DUF3365 PF11845.3 EJS41565.1 - 0.059 13.2 2.7 0.16 11.7 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) WD40 PF00400.27 EJS41566.1 - 2.8e-05 23.8 3.8 0.005 16.6 0.1 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoplasmin PF03066.10 EJS41566.1 - 0.64 9.5 4.0 0.28 10.6 0.7 1.8 2 0 0 2 2 2 0 Nucleoplasmin DUF3246 PF11596.3 EJS41566.1 - 0.93 8.7 6.0 0.18 11.0 0.9 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3246) Pkinase PF00069.20 EJS41567.1 - 5.2e-69 232.2 0.0 8.1e-69 231.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41567.1 - 2e-38 131.9 0.0 3.8e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS41567.1 - 6.1e-09 35.2 0.0 1.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EJS41567.1 - 0.0025 16.9 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS41567.1 - 0.0066 16.2 0.0 0.12 12.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EJS41567.1 - 0.018 13.8 0.0 0.052 12.3 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EJS41567.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 EJS41568.1 - 5.9e-65 218.9 0.0 9.6e-65 218.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41568.1 - 2.9e-39 134.7 0.0 4.8e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS41568.1 - 1.6e-08 33.8 0.0 2.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EJS41568.1 - 0.00057 19.2 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EJS41568.1 - 0.00068 18.7 0.1 0.0015 17.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS41568.1 - 0.0014 18.4 0.1 0.012 15.3 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DHFR_1 PF00186.14 EJS41569.1 - 1.5e-31 109.1 0.0 2.2e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase Oxysterol_BP PF01237.13 EJS41570.1 - 4.1e-89 298.5 2.3 5.1e-89 298.2 1.6 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF1539 PF07560.6 EJS41570.1 - 0.04 13.7 0.2 0.098 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) TruD PF01142.13 EJS41573.1 - 5.9e-66 222.6 1.0 7.5e-62 209.1 0.0 3.7 1 1 1 3 3 3 2 tRNA pseudouridine synthase D (TruD) Nbl1_Borealin_N PF10444.4 EJS41573.1 - 0.064 12.6 0.0 0.21 10.9 0.0 1.9 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal MOZ_SAS PF01853.13 EJS41574.1 - 1.1e-90 301.9 0.8 1.7e-90 301.3 0.5 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EJS41574.1 - 2e-21 75.4 0.6 4.4e-21 74.3 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Spc97_Spc98 PF04130.8 EJS41574.1 - 0.0074 14.6 0.0 0.016 13.5 0.0 1.5 1 1 0 1 1 1 1 Spc97 / Spc98 family Acetyltransf_1 PF00583.19 EJS41574.1 - 0.036 14.0 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DAGAT PF03982.8 EJS41575.1 - 3.4e-81 272.1 2.1 1.6e-72 243.7 0.0 2.1 1 1 1 2 2 2 2 Diacylglycerol acyltransferase adh_short PF00106.20 EJS41576.1 - 3.4e-12 46.5 0.1 5e-10 39.5 0.0 2.9 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EJS41576.1 - 0.00022 21.0 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EJS41576.1 - 0.006 15.7 0.0 0.027 13.5 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF4122 PF13498.1 EJS41576.1 - 0.091 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) Clp1 PF06807.9 EJS41577.1 - 4.6e-17 62.4 0.0 6.6e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EJS41577.1 - 6e-07 29.2 0.0 9.6e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EJS41577.1 - 0.00018 21.5 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 EJS41577.1 - 0.0018 17.7 0.0 0.0055 16.1 0.0 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EJS41577.1 - 0.018 15.5 0.0 0.057 13.9 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein AAA_14 PF13173.1 EJS41577.1 - 0.027 14.3 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EJS41577.1 - 0.049 13.1 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 EJS41577.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 EJS41577.1 - 0.11 12.4 0.0 0.43 10.5 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EJS41577.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 EJS41577.1 - 0.15 11.5 0.0 0.45 10.0 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EJS41577.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Rhodanese PF00581.15 EJS41578.1 - 4.2e-20 72.1 0.0 8.4e-12 45.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF2962 PF11176.3 EJS41579.1 - 5.1e-40 136.5 3.0 5.7e-40 136.4 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Acetyltransf_1 PF00583.19 EJS41580.1 - 3.9e-08 33.1 0.0 5.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EJS41580.1 - 1.2e-06 28.5 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EJS41580.1 - 0.0004 20.3 0.1 0.00057 19.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EJS41580.1 - 0.039 14.0 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EJS41580.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Sec63 PF02889.11 EJS41581.1 - 3.3e-21 75.8 0.0 7.7e-19 68.0 0.0 2.2 1 1 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 EJS41581.1 - 9e-19 66.9 0.4 8.9e-18 63.7 0.1 2.6 2 0 0 2 2 2 1 DnaJ domain TFR_dimer PF04253.10 EJS41582.1 - 3.7e-38 129.9 0.0 6.1e-38 129.2 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EJS41582.1 - 0.00054 19.6 0.0 0.0028 17.3 0.0 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M28 PF04389.12 EJS41582.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 EF-hand_7 PF13499.1 EJS41583.1 - 5e-25 87.4 10.4 1.2e-14 54.1 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EJS41583.1 - 1.8e-23 79.9 15.2 4.3e-08 31.8 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EJS41583.1 - 9.5e-20 68.6 10.9 3.6e-07 29.5 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EJS41583.1 - 1.5e-17 62.0 9.1 9.7e-06 24.7 0.0 3.7 3 1 1 4 4 4 3 EF hand EF-hand_8 PF13833.1 EJS41583.1 - 8.4e-17 60.5 12.6 1.9e-11 43.3 0.3 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EJS41583.1 - 9.7e-09 35.0 0.3 0.0012 18.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EJS41583.1 - 1.1e-06 28.3 1.3 0.006 16.2 0.1 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EJS41583.1 - 0.0022 17.9 0.8 0.51 10.3 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region VCBS PF13517.1 EJS41583.1 - 0.037 14.3 0.7 0.72 10.2 0.0 2.3 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MgtE_N PF03448.12 EJS41583.1 - 0.052 13.8 3.3 0.063 13.5 0.2 2.3 3 0 0 3 3 3 0 MgtE intracellular N domain Caleosin PF05042.8 EJS41583.1 - 0.075 12.5 0.6 0.88 9.1 0.0 2.6 1 1 1 3 3 3 0 Caleosin related protein Dockerin_1 PF00404.13 EJS41583.1 - 2.4 7.9 5.1 9.9 6.0 0.1 2.5 2 0 0 2 2 2 0 Dockerin type I repeat HIT PF01230.18 EJS41584.1 - 2.3e-21 76.1 0.2 4.1e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EJS41584.1 - 3e-14 53.2 2.2 1.1e-13 51.4 1.5 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2H2_4 PF13894.1 EJS41584.1 - 0.078 13.3 1.2 0.3 11.5 0.8 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger AAA PF00004.24 EJS41585.1 - 2.6e-42 144.1 0.0 4.8e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EJS41585.1 - 1.1e-06 28.7 0.6 7e-05 22.8 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EJS41585.1 - 1.4e-06 28.0 0.2 4.1e-05 23.3 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EJS41585.1 - 2.9e-05 24.0 0.0 7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EJS41585.1 - 7e-05 22.9 0.1 0.0057 16.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EJS41585.1 - 8.6e-05 21.6 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EJS41585.1 - 0.00017 21.2 0.1 0.00035 20.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EJS41585.1 - 0.00054 20.7 1.2 0.0019 19.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EJS41585.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EJS41585.1 - 0.0019 18.3 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EJS41585.1 - 0.0021 16.8 0.1 0.0038 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EJS41585.1 - 0.0042 16.5 0.6 0.028 13.8 0.3 2.2 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EJS41585.1 - 0.0053 15.9 0.2 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EJS41585.1 - 0.0057 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EJS41585.1 - 0.0076 15.6 0.1 0.0076 15.6 0.1 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 EJS41585.1 - 0.0096 15.5 0.3 0.022 14.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EJS41585.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EJS41585.1 - 0.013 15.4 1.1 0.02 14.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EJS41585.1 - 0.017 15.4 1.7 0.049 13.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EJS41585.1 - 0.019 14.0 0.1 0.093 11.8 0.0 2.2 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EJS41585.1 - 0.033 13.4 0.2 0.071 12.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EJS41585.1 - 0.064 12.1 0.1 0.13 11.0 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 EJS41585.1 - 0.066 12.2 4.5 0.12 11.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_3 PF07726.6 EJS41585.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EJS41585.1 - 0.089 12.4 0.1 0.33 10.6 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EJS41585.1 - 0.091 12.4 1.0 4 7.0 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase AAA_11 PF13086.1 EJS41585.1 - 0.18 11.3 3.6 0.87 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EJS41585.1 - 0.95 9.7 3.3 2.4 8.4 0.0 2.8 2 1 1 3 3 3 0 ABC transporter Fib_alpha PF08702.5 EJS41585.1 - 0.99 9.5 4.7 2.1 8.4 3.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.1 EJS41585.1 - 2.9 8.1 11.2 5.5 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 EJS41585.1 - 9.4 5.7 10.1 17 4.9 7.0 1.4 1 0 0 1 1 1 0 IncA protein NTP_transf_3 PF12804.2 EJS41586.1 - 1.6e-05 25.0 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EJS41586.1 - 0.0012 18.2 4.3 2.7 7.6 0.0 3.8 1 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 EJS41586.1 - 0.0031 16.1 1.9 0.06 11.8 0.4 2.2 1 1 1 2 2 2 2 L-fucokinase Hexapep_2 PF14602.1 EJS41586.1 - 0.062 12.8 1.3 0.19 11.3 0.1 2.4 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase ATP_bind_1 PF03029.12 EJS41587.1 - 1.2e-79 267.1 0.1 1.5e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EJS41587.1 - 5.4e-05 23.5 0.8 0.32 11.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EJS41587.1 - 0.00045 21.0 3.1 0.0016 19.2 0.0 2.9 2 2 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EJS41587.1 - 0.0022 17.5 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 EJS41587.1 - 0.0046 16.8 0.0 0.02 14.8 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EJS41587.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain ArgK PF03308.11 EJS41587.1 - 0.026 13.2 0.2 0.054 12.2 0.0 1.5 2 0 0 2 2 2 0 ArgK protein AAA_33 PF13671.1 EJS41587.1 - 0.044 13.6 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EJS41587.1 - 0.099 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EJS41587.1 - 0.15 11.6 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain TBCA PF02970.11 EJS41589.1 - 4.1e-29 100.4 8.2 4.9e-29 100.2 5.6 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF3010 PF11215.3 EJS41589.1 - 0.021 14.7 0.2 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) LON PF02190.11 EJS41589.1 - 0.079 12.6 2.0 0.096 12.3 1.4 1.0 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain DUF1664 PF07889.7 EJS41589.1 - 0.097 12.4 0.4 0.15 11.8 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PRD PF00874.15 EJS41589.1 - 0.12 12.5 0.6 0.2 11.7 0.4 1.5 1 0 0 1 1 1 0 PRD domain Cor1 PF04803.7 EJS41589.1 - 0.17 11.6 3.8 0.24 11.1 2.6 1.3 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region IncA PF04156.9 EJS41589.1 - 0.21 11.1 7.8 0.26 10.8 5.4 1.2 1 0 0 1 1 1 0 IncA protein FliD_N PF02465.13 EJS41589.1 - 0.27 11.6 1.9 0.29 11.4 0.3 1.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF342 PF03961.8 EJS41589.1 - 0.51 8.6 4.8 0.56 8.5 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pkinase PF00069.20 EJS41590.1 - 4.6e-57 193.1 4.5 9.2e-54 182.3 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41590.1 - 4e-19 68.7 0.0 1.4e-18 66.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.27 EJS41591.1 - 1.3e-40 135.8 21.9 1.9e-08 33.8 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EJS41591.1 - 0.00057 18.1 3.8 0.42 8.6 0.0 3.1 3 1 0 3 3 3 2 Nucleoporin Nup120/160 DivIC PF04977.10 EJS41591.1 - 0.062 12.7 0.2 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator MbeD_MobD PF04899.7 EJS41591.1 - 0.081 12.8 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 MbeD/MobD like V_ATPase_I PF01496.14 EJS41592.1 - 0 1035.2 3.6 0 1035.0 2.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Mtc PF03820.12 EJS41593.1 - 8.1e-133 441.8 0.0 9.1e-133 441.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Polysacc_synt_C PF14667.1 EJS41593.1 - 3.2 7.5 6.9 0.47 10.2 2.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain WD40 PF00400.27 EJS41594.1 - 5.8e-40 133.7 12.4 2.1e-08 33.7 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 EJS41594.1 - 3.8e-25 87.6 0.0 6.8e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EJS41594.1 - 1.7e-08 33.0 6.2 0.0042 15.2 0.3 3.5 2 2 1 3 3 3 3 Nucleoporin Nup120/160 MFS_1 PF07690.11 EJS41595.1 - 2.7e-25 88.8 33.7 2.7e-25 88.8 23.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EJS41595.1 - 0.00024 19.8 12.8 0.00024 19.8 8.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3560 PF12083.3 EJS41595.1 - 0.039 14.0 1.1 0.054 13.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) IPPT PF01715.12 EJS41596.1 - 3.3e-95 317.8 0.2 4.4e-95 317.4 0.1 1.2 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 EJS41596.1 - 2.4e-06 28.3 0.2 8.8e-06 26.5 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EJS41596.1 - 1.3e-05 25.5 0.0 0.0002 21.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain IPT PF01745.11 EJS41596.1 - 1.8e-05 24.0 0.1 0.00016 20.9 0.0 2.4 2 0 0 2 2 2 1 Isopentenyl transferase AAA_22 PF13401.1 EJS41596.1 - 0.0012 19.0 0.0 0.21 11.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EJS41596.1 - 0.0021 17.9 0.0 0.0062 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EJS41596.1 - 0.0028 16.7 0.0 0.0072 15.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EJS41596.1 - 0.012 15.8 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 EJS41596.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EJS41596.1 - 0.061 12.7 0.1 0.18 11.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 EJS41596.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_14 PF13173.1 EJS41596.1 - 0.081 12.8 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 EJS41596.1 - 0.086 12.6 0.1 4.4 7.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase T2SE PF00437.15 EJS41596.1 - 0.11 11.3 0.2 0.21 10.4 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.18 EJS41596.1 - 0.11 11.8 0.5 0.28 10.5 0.2 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain BRO1 PF03097.13 EJS41597.1 - 3.8e-96 322.0 8.3 3.8e-96 322.0 5.8 2.2 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EJS41597.1 - 5.1e-38 130.7 21.0 6.5e-36 123.8 14.6 2.5 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV HEM4 PF02602.10 EJS41599.1 - 3.2e-44 150.8 0.0 3.7e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DpnII PF04556.7 EJS41599.1 - 0.058 12.4 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 DpnII restriction endonuclease FSH1 PF03959.8 EJS41600.1 - 1.5e-67 227.1 0.0 1.7e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EJS41600.1 - 1.2e-07 31.5 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EJS41600.1 - 0.0051 16.7 0.0 0.21 11.4 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EJS41600.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EJS41600.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Phosducin PF02114.11 EJS41601.1 - 8.8e-07 27.9 5.5 2.8e-05 22.9 3.8 2.1 1 1 0 1 1 1 1 Phosducin RUN PF02759.14 EJS41601.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 RUN domain His_Phos_1 PF00300.17 EJS41602.1 - 8.6e-33 113.6 0.3 1.1e-32 113.3 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rhodanese PF00581.15 EJS41603.1 - 2.3e-21 76.2 0.0 2.8e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.15 EJS41604.1 - 4.5e-12 46.3 0.0 5.5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF947 PF06102.7 EJS41605.1 - 5.7e-45 153.1 30.2 5.7e-45 153.1 20.9 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF947) SNF2_N PF00176.18 EJS41606.1 - 5.9e-84 281.3 0.5 1.6e-83 279.9 0.4 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EJS41606.1 - 3.1e-18 65.4 0.1 3.8e-16 58.7 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EJS41606.1 - 3.9e-16 58.9 2.0 3.9e-16 58.9 1.4 3.1 2 1 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex Bromodomain PF00439.20 EJS41606.1 - 3.2e-15 55.7 3.5 3.9e-15 55.5 0.1 2.8 3 0 0 3 3 3 1 Bromodomain QLQ PF08880.6 EJS41606.1 - 8.7e-11 41.0 0.2 8.7e-11 41.0 0.2 3.1 3 0 0 3 3 3 1 QLQ P5-ATPase PF12409.3 EJS41607.1 - 3.1e-38 130.2 0.0 1.4e-37 128.1 0.0 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 EJS41607.1 - 1.3e-27 96.3 0.0 3.1e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EJS41607.1 - 2.5e-25 89.7 0.0 5.7e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EJS41607.1 - 2e-18 67.5 0.0 1.1e-16 61.8 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EJS41607.1 - 2.3e-06 27.4 0.0 5.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EJS41607.1 - 0.00057 19.5 0.1 1.2 8.6 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EJS41607.1 - 0.067 12.6 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus AvrE PF11725.3 EJS41607.1 - 8.6 3.2 5.3 15 2.3 3.7 1.3 1 0 0 1 1 1 0 Pathogenicity factor Mpv17_PMP22 PF04117.7 EJS41608.1 - 8.1e-21 73.4 0.3 8.1e-21 73.4 0.2 2.6 2 1 1 3 3 3 1 Mpv17 / PMP22 family DUF4234 PF14018.1 EJS41608.1 - 5.4 6.8 9.9 5.7 6.7 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) RRS1 PF04939.7 EJS41609.1 - 1.9e-64 216.0 6.3 2.2e-64 215.8 4.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Membr_traf_MHD PF10540.4 EJS41610.1 - 1.7e-12 47.2 2.1 1.4e-11 44.3 0.0 3.0 3 0 0 3 3 3 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EJS41610.1 - 1.2e-10 41.1 0.0 5.1e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 C2 domain DUF4535 PF15054.1 EJS41610.1 - 0.06 12.7 0.1 0.16 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) CybS PF05328.7 EJS41611.1 - 8.5e-44 148.4 0.0 1.4e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 CybS MBF1 PF08523.5 EJS41612.1 - 2e-28 98.1 1.3 5.6e-28 96.7 0.9 1.7 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EJS41612.1 - 7.8e-13 48.0 0.1 1.1e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EJS41612.1 - 1.3e-05 25.2 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EJS41612.1 - 0.00014 21.8 0.1 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TRAP-gamma PF07074.7 EJS41612.1 - 0.19 11.2 1.2 0.26 10.8 0.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) ChAPs PF09295.5 EJS41613.1 - 2e-171 570.1 1.3 2.7e-171 569.7 0.9 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.1 EJS41613.1 - 0.0012 18.4 0.5 0.27 11.1 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EJS41613.1 - 0.0031 17.2 0.2 0.72 9.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EJS41613.1 - 0.0064 16.1 1.1 2.7 7.7 0.3 3.2 3 0 0 3 3 3 1 TPR repeat Pox_A3L PF05288.6 EJS41613.1 - 0.045 13.4 0.6 1.2 8.8 0.3 2.6 2 0 0 2 2 2 0 Poxvirus A3L Protein Apc3 PF12895.2 EJS41613.1 - 0.24 11.5 3.1 2.9 8.0 0.4 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Leader_CPA1 PF08252.6 EJS41614.1 - 2.5e-17 61.6 7.6 2.6e-17 61.5 5.3 1.0 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide SNF2_N PF00176.18 EJS41615.1 - 3.9e-81 272.1 0.7 8e-81 271.0 0.5 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EJS41615.1 - 1.1e-44 150.8 3.3 1.1e-44 150.8 2.3 3.3 4 0 0 4 4 4 1 SLIDE HAND PF09110.6 EJS41615.1 - 1.3e-35 122.2 8.9 1.3e-35 122.2 6.2 3.2 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 EJS41615.1 - 7.3e-17 61.0 0.0 3.8e-16 58.7 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EJS41615.1 - 8.2e-07 28.6 0.0 2.3e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EJS41615.1 - 0.00057 20.0 0.2 0.0043 17.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EJS41615.1 - 0.023 14.5 1.8 0.22 11.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain AHH PF14412.1 EJS41616.1 - 0.0055 16.6 1.4 0.099 12.6 1.0 2.0 1 1 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH PTRF_SDPR PF15237.1 EJS41616.1 - 0.02 14.3 0.2 0.026 13.9 0.1 1.2 1 0 0 1 1 1 0 PTRF/SDPR family Baculo_PEP_C PF04513.7 EJS41616.1 - 0.027 14.2 0.4 0.028 14.2 0.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LXG PF04740.7 EJS41616.1 - 0.055 13.2 0.6 0.052 13.3 0.4 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Med11 PF10280.4 EJS41616.1 - 0.056 13.4 0.1 0.06 13.3 0.1 1.2 1 0 0 1 1 1 0 Mediator complex protein IF2_N PF04760.10 EJS41616.1 - 0.06 13.0 0.1 0.15 11.7 0.1 1.6 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DUF964 PF06133.6 EJS41616.1 - 0.062 13.3 1.4 0.078 12.9 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF964) Corona_S2 PF01601.11 EJS41616.1 - 0.075 11.1 0.1 0.071 11.2 0.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein BLOC1_2 PF10046.4 EJS41616.1 - 0.097 12.8 1.7 0.1 12.7 1.1 1.3 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ACCA PF03255.9 EJS41616.1 - 0.13 11.7 0.5 0.17 11.4 0.4 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TPT PF03151.11 EJS41617.1 - 5.1e-25 87.8 15.1 1e-24 86.9 4.1 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EJS41617.1 - 2e-06 27.8 35.3 4.3e-05 23.5 6.2 4.0 4 0 0 4 4 4 3 EamA-like transporter family UAA PF08449.6 EJS41617.1 - 0.0016 17.4 7.4 0.0016 17.4 5.1 2.9 3 0 0 3 3 3 2 UAA transporter family Tetraspannin PF00335.15 EJS41617.1 - 3.9 6.6 12.9 0.033 13.4 2.6 2.4 2 1 0 2 2 2 0 Tetraspanin family SART-1 PF03343.8 EJS41618.1 - 6e-71 239.5 58.3 2.7e-61 207.6 36.1 4.0 1 1 1 2 2 2 2 SART-1 family CTP_transf_1 PF01148.15 EJS41619.1 - 4.1e-23 82.3 13.2 9.7e-20 71.3 3.0 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family Cation_efflux PF01545.16 EJS41621.1 - 4.9e-77 258.7 4.5 6.2e-77 258.4 3.1 1.0 1 0 0 1 1 1 1 Cation efflux family RRM_1 PF00076.17 EJS41622.1 - 1e-27 95.5 2.6 1.4e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS41622.1 - 4e-21 74.7 0.3 8.4e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS41622.1 - 1.7e-14 53.3 3.6 2e-07 30.7 0.3 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EJS41622.1 - 0.00032 20.3 0.0 0.057 13.1 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 Glyco_transf_8 PF01501.15 EJS41623.1 - 3.6e-05 23.2 8.1 0.0002 20.8 3.7 2.9 2 1 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EJS41623.1 - 0.0027 17.0 1.6 0.008 15.5 1.1 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative PMT PF02366.13 EJS41624.1 - 1.4e-93 312.7 20.3 1.4e-93 312.7 14.1 1.7 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EJS41624.1 - 4.4e-25 88.3 0.0 1.1e-24 87.0 0.0 1.6 1 1 0 1 1 1 1 MIR domain LDB19 PF13002.2 EJS41625.1 - 8.2e-98 325.5 1.3 1.2e-97 324.9 0.9 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EJS41625.1 - 2.7e-06 27.2 0.2 8.7e-06 25.6 0.1 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Aldedh PF00171.17 EJS41626.1 - 2e-13 49.5 0.4 3.4e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.12 EJS41626.1 - 0.0052 15.7 0.0 0.012 14.5 0.0 1.6 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) Hph PF13694.1 EJS41627.1 - 6.4e-43 147.0 11.4 6.4e-43 147.0 7.9 3.7 3 1 0 3 3 3 1 Sec63/Sec62 complex-interacting family FliJ PF02050.11 EJS41627.1 - 0.0049 16.9 2.0 0.015 15.3 0.7 2.4 1 1 1 2 2 2 1 Flagellar FliJ protein Med15_fungi PF05397.7 EJS41627.1 - 0.0054 16.6 0.2 0.0054 16.6 0.2 1.8 2 0 0 2 2 2 1 Mediator complex subunit 15 DUF3671 PF12420.3 EJS41627.1 - 0.041 13.8 1.7 0.1 12.5 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function Myosin_head PF00063.16 EJS41628.1 - 4.8e-267 887.5 12.3 4.8e-267 887.5 8.5 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EJS41628.1 - 4e-35 119.8 1.6 4e-35 119.8 1.1 3.2 3 0 0 3 3 3 1 DIL domain AAA_22 PF13401.1 EJS41628.1 - 0.00044 20.4 3.1 0.0012 18.9 0.0 3.2 2 0 0 2 2 2 1 AAA domain RNase_P_Rpp14 PF01900.14 EJS41628.1 - 0.011 15.6 0.2 0.032 14.1 0.2 1.8 1 0 0 1 1 1 0 Rpp14/Pop5 family Myosin_N PF02736.14 EJS41628.1 - 0.016 14.8 0.3 0.04 13.5 0.2 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain IQ PF00612.22 EJS41628.1 - 0.023 14.3 13.9 2.4 8.0 0.1 5.4 5 0 0 5 5 5 0 IQ calmodulin-binding motif AAA_19 PF13245.1 EJS41628.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF2937 PF11157.3 EJS41628.1 - 0.5 9.6 5.1 0.41 9.9 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Reo_sigmaC PF04582.7 EJS41628.1 - 2 7.5 10.6 0.19 10.8 1.4 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein UPF0449 PF15136.1 EJS41629.1 - 0.011 15.8 0.8 0.011 15.8 0.6 4.7 2 1 3 5 5 5 0 Uncharacterised protein family UPF0449 TetR_C_4 PF08359.6 EJS41629.1 - 0.16 11.9 9.9 0.088 12.7 0.6 3.3 3 0 0 3 3 3 0 YsiA-like protein, C-terminal region ECH PF00378.15 EJS41630.1 - 3e-14 52.7 0.0 1.3e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SPA PF08616.5 EJS41630.1 - 0.0023 17.6 0.1 0.0042 16.7 0.1 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis WH1 PF00568.18 EJS41631.1 - 6.2e-37 125.7 0.0 8.5e-37 125.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EJS41631.1 - 8.7e-06 25.1 1.0 1.9e-05 24.1 0.7 1.6 1 0 0 1 1 1 1 WH2 motif Aminotran_5 PF00266.14 EJS41632.1 - 3.6e-31 108.2 0.0 4.7e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Ras PF00071.17 EJS41633.1 - 1.4e-51 174.0 0.0 1.8e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS41633.1 - 5.5e-18 65.6 0.0 1.2e-17 64.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EJS41633.1 - 4.1e-12 45.6 0.0 5.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EJS41633.1 - 0.00024 21.2 0.2 0.0019 18.3 0.2 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EJS41633.1 - 0.0006 19.0 0.0 0.00082 18.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EJS41633.1 - 0.0056 16.1 0.5 0.05 13.0 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EJS41633.1 - 0.0091 15.2 0.0 0.015 14.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Pox_A32 PF04665.7 EJS41633.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EJS41633.1 - 0.016 13.9 2.1 0.76 8.3 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit KaiC PF06745.8 EJS41633.1 - 0.019 14.0 0.2 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EJS41633.1 - 0.057 13.5 0.2 0.17 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EJS41633.1 - 0.068 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EJS41633.1 - 0.12 12.0 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 EJS41633.1 - 0.16 11.6 0.6 0.49 10.0 0.4 1.8 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 GTP_EFTU PF00009.22 EJS41634.1 - 3.9e-61 205.7 0.3 5.2e-61 205.3 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EJS41634.1 - 5.2e-27 93.9 0.0 1.6e-26 92.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EJS41634.1 - 6.6e-20 70.9 1.6 1.9e-19 69.5 1.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EJS41634.1 - 1.3e-05 24.7 0.2 3.3e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EJS41634.1 - 3.8e-05 23.6 0.0 6.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EJS41634.1 - 0.002 18.6 0.0 0.0037 17.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EJS41634.1 - 0.046 13.2 0.4 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DisA_N PF02457.11 EJS41634.1 - 0.049 12.7 0.2 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding CbiA PF01656.18 EJS41634.1 - 4 6.8 6.6 2.8e+02 0.7 4.6 2.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cellulase PF00150.13 EJS41635.1 - 3.8e-12 46.0 5.7 7e-12 45.1 0.0 2.6 2 1 1 3 3 3 2 Cellulase (glycosyl hydrolase family 5) SNF2_N PF00176.18 EJS41636.1 - 5.8e-65 219.0 0.1 5.8e-65 219.0 0.1 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EJS41636.1 - 3.7e-11 42.7 0.0 1.1e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EJS41636.1 - 1.8e-05 24.3 2.3 4.1e-05 23.2 1.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EJS41636.1 - 0.00063 19.7 1.3 0.0016 18.3 0.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EJS41636.1 - 0.00082 19.1 3.1 0.0017 18.1 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EJS41636.1 - 0.002 17.8 0.2 0.0065 16.1 0.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EJS41636.1 - 0.0073 15.9 1.1 0.018 14.6 0.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EJS41636.1 - 0.015 14.9 3.2 0.031 13.9 2.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EJS41636.1 - 0.041 13.4 0.8 0.1 12.1 0.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TFIIA PF03153.8 EJS41637.1 - 3.9e-60 204.7 25.7 8.4e-34 118.0 11.5 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit EutQ PF06249.7 EJS41637.1 - 7.1 6.1 7.8 1.1 8.8 1.3 2.3 3 0 0 3 3 3 0 Ethanolamine utilisation protein EutQ Kinetocho_Slk19 PF12709.2 EJS41638.1 - 5.3e-31 106.5 18.4 5.3e-31 106.5 12.8 9.2 3 2 5 8 8 8 1 Central kinetochore-associated IncA PF04156.9 EJS41638.1 - 0.31 10.6 110.6 0.73 9.4 12.1 7.3 1 1 6 7 7 7 0 IncA protein Radical_SAM PF04055.16 EJS41639.1 - 6.7e-15 55.6 0.0 1.1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Phyto-Amp PF15438.1 EJS41639.1 - 0.18 11.4 0.8 0.49 10.0 0.5 1.7 2 0 0 2 2 2 0 Antigenic membrane protein of phytoplasma SpoU_methylase PF00588.14 EJS41641.1 - 1.5e-25 89.7 0.0 4.7e-25 88.1 0.0 1.8 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EJS41641.1 - 5.2e-11 42.5 0.0 1.1e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding IGPD PF00475.13 EJS41642.1 - 2.2e-61 205.9 0.6 3.7e-61 205.2 0.4 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DEAD PF00270.24 EJS41643.1 - 2.5e-47 160.4 0.0 3.2e-46 156.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS41643.1 - 8.2e-28 96.0 0.1 2.2e-27 94.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EJS41643.1 - 0.05 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MMR_HSR1 PF01926.18 EJS41644.1 - 1.4e-09 37.9 0.0 4.6e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EJS41644.1 - 2.3e-05 23.6 0.0 5.7e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EJS41644.1 - 0.0012 18.1 0.1 0.0063 15.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_10 PF12846.2 EJS41644.1 - 0.0037 16.7 0.1 0.53 9.6 0.0 2.6 3 0 0 3 3 3 1 AAA-like domain GTP_EFTU PF00009.22 EJS41644.1 - 0.014 14.8 0.2 0.58 9.5 0.1 2.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 EJS41644.1 - 0.024 14.7 0.3 0.43 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 EJS41644.1 - 0.062 13.6 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter PHD_2 PF13831.1 EJS41644.1 - 0.17 11.1 1.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 PHD-finger Noc2 PF03715.8 EJS41645.1 - 6e-128 425.8 4.4 6e-128 425.8 3.1 1.8 2 0 0 2 2 2 1 Noc2p family RNA_pol_Rpb2_6 PF00562.23 EJS41646.1 - 2e-120 402.1 0.4 3.7e-120 401.2 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EJS41646.1 - 3.1e-62 209.1 1.4 5.5e-62 208.3 1.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EJS41646.1 - 3.7e-42 143.9 4.3 5.7e-42 143.2 1.9 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EJS41646.1 - 1.9e-30 104.9 0.1 5.8e-30 103.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EJS41646.1 - 3.1e-26 90.9 2.1 5.5e-26 90.1 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EJS41646.1 - 7.8e-19 67.2 0.0 1.8e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EJS41646.1 - 3.5e-13 49.2 0.2 1.7e-12 47.0 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 EJS41646.1 - 0.0031 15.9 0.1 0.0058 15.0 0.1 1.3 1 0 0 1 1 1 1 Baculovirus Y142 protein NAPRTase PF04095.11 EJS41647.1 - 5.5e-73 245.2 0.0 7.2e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family RNA_pol_N PF01194.12 EJS41648.1 - 2e-29 101.3 0.4 2.2e-29 101.2 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EJS41648.1 - 0.043 13.9 0.2 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) YhfH PF14149.1 EJS41648.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 YhfH-like protein Dynamin_N PF00350.18 EJS41649.1 - 2.4e-42 144.6 1.9 2.4e-42 144.5 0.1 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EJS41649.1 - 0.00032 20.6 0.1 0.0024 17.8 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EJS41649.1 - 0.00061 20.2 0.0 0.0018 18.7 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EJS41649.1 - 0.048 13.6 0.6 0.28 11.1 0.1 2.4 2 2 0 2 2 2 0 AAA ATPase domain DUF1140 PF06600.6 EJS41649.1 - 0.065 13.3 2.0 6.9 6.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1140) FolB PF02152.13 EJS41650.1 - 0.016 15.3 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 Dihydroneopterin aldolase YqeY PF09424.5 EJS41651.1 - 2.7e-20 72.6 6.0 3.8e-20 72.2 4.2 1.2 1 0 0 1 1 1 1 Yqey-like protein Pox_A3L PF05288.6 EJS41651.1 - 0.019 14.6 0.9 0.068 12.9 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A3L Protein Phosphodiest PF01663.17 EJS41651.1 - 0.08 12.2 0.1 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase SecIII_SopE_N PF05364.9 EJS41651.1 - 0.16 11.8 3.6 2.5 8.0 0.1 2.8 3 1 0 3 3 3 0 Salmonella type III secretion SopE effector N-terminus GRAB PF10375.4 EJS41652.1 - 6.3e-07 28.7 1.2 2.4e-06 26.9 0.8 2.1 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Spc7 PF08317.6 EJS41652.1 - 4.1e-06 25.6 25.6 4.1e-06 25.6 17.7 4.0 1 1 3 4 4 4 2 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EJS41652.1 - 0.00032 20.4 33.6 0.0022 17.7 13.9 6.2 1 1 4 6 6 6 3 TATA element modulatory factor 1 DNA binding DUF3584 PF12128.3 EJS41652.1 - 0.0013 16.2 33.5 0.0013 16.2 23.2 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3584) IncA PF04156.9 EJS41652.1 - 0.0018 17.8 23.3 0.0018 17.8 16.1 4.0 1 1 2 3 3 3 2 IncA protein Reo_sigmaC PF04582.7 EJS41652.1 - 0.013 14.7 1.5 0.013 14.7 1.0 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EJS41652.1 - 0.015 15.1 21.7 0.015 15.1 15.0 4.4 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EJS41652.1 - 0.061 12.7 60.9 0.085 12.3 13.7 3.6 1 1 3 4 4 4 0 Intermediate filament protein GAS PF13851.1 EJS41652.1 - 0.3 10.2 69.5 1.8 7.6 6.2 4.4 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 EJS41652.1 - 0.87 9.1 62.2 0.045 13.2 11.9 4.7 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 EJS41652.1 - 1.4 8.7 41.1 0.19 11.5 4.0 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) MbeD_MobD PF04899.7 EJS41652.1 - 2 8.3 15.2 1.1 9.1 1.0 4.6 3 1 2 5 5 5 0 MbeD/MobD like AAA_13 PF13166.1 EJS41652.1 - 4.9 5.4 60.4 0.56 8.6 19.3 2.6 1 1 1 2 2 2 0 AAA domain THOC7 PF05615.8 EJS41652.1 - 6.1 7.1 58.3 3.4 7.9 10.5 5.1 1 1 4 5 5 5 0 Tho complex subunit 7 RFC1 PF08519.7 EJS41653.1 - 2.3e-59 199.5 0.0 1.8e-57 193.4 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 EJS41653.1 - 1.7e-13 50.8 0.0 3.9e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 EJS41653.1 - 9.9e-10 38.4 0.1 5.9e-09 35.9 0.0 2.5 3 0 0 3 3 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.10 EJS41653.1 - 3.2e-07 29.4 0.1 0.0002 20.2 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EJS41653.1 - 7.1e-06 26.8 0.1 8.5e-05 23.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EJS41653.1 - 1.8e-05 23.9 0.0 3.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EJS41653.1 - 2.3e-05 24.5 0.0 0.00018 21.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EJS41653.1 - 0.00041 20.4 0.0 0.0048 16.9 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EJS41653.1 - 0.0012 18.7 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EJS41653.1 - 0.002 18.0 0.0 0.0049 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EJS41653.1 - 0.0031 17.8 0.2 0.013 15.8 0.0 2.2 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EJS41653.1 - 0.0049 17.0 0.0 0.015 15.4 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 EJS41653.1 - 0.0064 16.0 0.3 0.02 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EJS41653.1 - 0.011 15.4 0.0 0.038 13.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain PTCB-BRCT PF12738.2 EJS41653.1 - 0.018 14.8 0.5 0.05 13.4 0.0 2.1 2 0 0 2 2 1 0 twin BRCT domain AAA_5 PF07728.9 EJS41653.1 - 0.022 14.4 0.2 0.2 11.3 0.0 2.5 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Mito_carr PF00153.22 EJS41655.1 - 7.6e-72 237.1 2.5 6.2e-27 93.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EJS41655.1 - 0.047 13.7 0.4 0.65 10.0 0.1 2.7 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Sad1_UNC PF07738.8 EJS41656.1 - 3.1e-34 117.6 0.1 6.2e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ISN1 PF06437.6 EJS41657.1 - 3.1e-182 605.8 0.0 3.5e-182 605.6 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Proteasome PF00227.21 EJS41658.1 - 2.7e-48 163.7 0.1 3.8e-48 163.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EJS41658.1 - 1.7e-15 55.9 0.0 3.8e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Xpo1 PF08389.7 EJS41659.1 - 1.2e-25 90.1 5.0 1.2e-25 90.1 3.5 4.5 4 1 0 4 4 4 1 Exportin 1-like protein Choline_transpo PF04515.7 EJS41660.1 - 6.6e-98 327.5 20.4 6.6e-98 327.5 14.1 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF410 PF04190.8 EJS41661.1 - 1e-97 326.7 2.5 1.2e-97 326.5 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF2802 PF10975.3 EJS41661.1 - 0.077 12.7 0.1 0.2 11.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2802) RHD3 PF05879.7 EJS41662.1 - 1.2e-283 942.5 15.1 1.4e-283 942.4 10.5 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EJS41662.1 - 1.9e-06 27.1 3.8 8.2e-06 25.0 0.1 2.7 2 1 1 3 3 3 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EJS41662.1 - 1.8e-05 24.6 0.0 6.8e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EJS41662.1 - 0.00062 19.7 0.1 0.002 18.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EJS41662.1 - 0.0015 18.9 0.0 0.0069 16.8 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EJS41662.1 - 0.024 14.9 0.2 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter PIN_4 PF13638.1 EJS41663.1 - 1.6e-31 109.1 0.2 3.8e-31 107.9 0.1 1.7 1 0 0 1 1 1 1 PIN domain Ribosomal_S28e PF01200.13 EJS41664.1 - 9.3e-34 114.9 4.0 1e-33 114.8 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e tRNA-synt_1c PF00749.16 EJS41665.1 - 2.1e-114 381.4 0.0 3.5e-114 380.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 EJS41665.1 - 3.9e-56 189.0 1.8 6.9e-56 188.2 1.3 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 EJS41665.1 - 3.2e-33 114.8 0.1 1e-31 109.9 0.0 2.5 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 EJS41665.1 - 7e-25 87.5 4.6 1.8e-24 86.2 3.2 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DAGK_cat PF00781.19 EJS41666.1 - 1.2e-25 89.4 0.0 2.2e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain tify PF06200.9 EJS41666.1 - 0.17 11.1 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 tify domain Med4 PF10018.4 EJS41667.1 - 1.7e-40 138.4 2.3 8.2e-40 136.2 1.5 1.9 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 MBOAT PF03062.14 EJS41668.1 - 5.6e-70 236.0 9.3 5.6e-70 236.0 6.5 2.0 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ferrochelatase PF00762.14 EJS41669.1 - 2.6e-90 302.6 0.0 3e-90 302.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Iso_dh PF00180.15 EJS41670.1 - 2.2e-103 345.8 0.0 2.7e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metallophos PF00149.23 EJS41671.1 - 2.5e-08 33.5 0.1 1.3e-07 31.2 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EJS41671.1 - 0.041 13.7 0.0 0.18 11.6 0.0 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain UBA PF00627.26 EJS41672.1 - 2.3e-10 39.9 0.2 9.3e-10 38.0 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EJS41672.1 - 0.0003 20.2 0.0 0.00068 19.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.11 EJS41672.1 - 0.021 14.3 0.2 0.19 11.2 0.0 2.8 3 1 0 3 3 3 0 CUE domain Sporozoite_P67 PF05642.6 EJS41672.1 - 0.06 11.1 1.8 0.097 10.5 1.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_LMP1 PF05297.6 EJS41672.1 - 5.8 5.7 8.2 9.2 5.0 5.7 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Actin PF00022.14 EJS41673.1 - 2.8e-28 98.4 0.0 1.2e-21 76.6 0.0 3.2 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EJS41673.1 - 0.0005 18.7 0.0 0.012 14.2 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Nop14 PF04147.7 EJS41673.1 - 0.14 10.0 25.4 0.31 8.9 17.6 1.6 1 0 0 1 1 1 0 Nop14-like family CoA_binding PF02629.14 EJS41674.1 - 1.3e-26 92.9 2.8 4.1e-26 91.3 0.5 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EJS41674.1 - 3.1e-23 82.0 0.7 5e-23 81.3 0.5 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EJS41674.1 - 2.6e-07 30.3 0.7 4e-07 29.7 0.1 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EJS41674.1 - 1.5e-05 25.0 0.0 3.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Toprim_Crpt PF13342.1 EJS41674.1 - 0.036 13.6 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase IlvN PF07991.7 EJS41674.1 - 0.062 12.6 0.4 0.38 10.0 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain TPK_catalytic PF04263.11 EJS41675.1 - 7.3e-22 77.2 0.0 9.3e-18 63.9 0.0 2.2 2 0 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EJS41675.1 - 2.4e-13 49.6 1.5 2.5e-13 49.5 0.2 1.8 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain KH_1 PF00013.24 EJS41676.1 - 0.0003 20.3 0.4 0.00084 18.9 0.3 1.7 1 0 0 1 1 1 1 KH domain Sec16_N PF12935.2 EJS41676.1 - 0.038 13.8 2.1 0.053 13.4 1.4 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus RNA_pol_Rpb2_6 PF00562.23 EJS41677.1 - 1.3e-126 422.5 0.2 2.3e-126 421.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EJS41677.1 - 1.4e-72 242.9 0.1 2.1e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EJS41677.1 - 1.2e-51 174.8 0.0 2.3e-51 173.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EJS41677.1 - 2.8e-30 104.3 0.1 6.9e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EJS41677.1 - 1.2e-28 98.6 1.4 2.2e-28 97.8 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EJS41677.1 - 6.3e-22 77.1 0.1 1.8e-21 75.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EJS41677.1 - 5.2e-19 67.9 1.3 1.2e-18 66.7 0.9 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Secretin_N_2 PF07655.8 EJS41678.1 - 0.099 13.0 4.2 0.18 12.1 2.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF676 PF05057.9 EJS41679.1 - 1.9e-59 200.5 0.0 2.6e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EJS41679.1 - 0.00019 21.0 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EJS41679.1 - 0.028 14.1 0.0 0.092 12.5 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.8 EJS41679.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF642 PF04862.7 EJS41680.1 - 0.062 12.9 0.4 0.96 9.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF642) Pkinase PF00069.20 EJS41681.1 - 1.8e-52 178.0 0.0 2.6e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41681.1 - 4.9e-17 61.8 0.0 7.1e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EJS41681.1 - 3.7e-07 30.1 0.0 2.3e-06 27.5 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EJS41681.1 - 0.0078 15.8 0.1 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Aconitase_B_N PF11791.3 EJS41681.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 Aconitate B N-terminal domain Imm44 PF15584.1 EJS41682.1 - 0.1 12.4 0.3 3.4 7.5 0.0 2.8 3 0 0 3 3 3 0 Immunity protein 44 Ribosomal_L3 PF00297.17 EJS41683.1 - 7.3e-122 405.8 9.0 8.8e-122 405.5 6.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Cytochrom_C1 PF02167.10 EJS41684.1 - 7.8e-84 280.7 0.0 9.4e-84 280.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EJS41684.1 - 0.00058 19.9 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EJS41684.1 - 0.0051 17.6 0.4 0.014 16.2 0.1 1.9 2 1 0 2 2 2 1 Cytochrome c Alg6_Alg8 PF03155.10 EJS41686.1 - 1.6e-167 558.1 42.8 1.8e-167 557.9 29.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Vps5 PF09325.5 EJS41687.1 - 4.6e-75 251.9 11.5 4.6e-75 251.9 8.0 1.7 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 EJS41687.1 - 2.1e-23 82.2 1.2 7.3e-23 80.5 0.4 2.3 2 0 0 2 2 2 1 PX domain RabGAP-TBC PF00566.13 EJS41688.1 - 1.3e-49 168.5 2.8 1.3e-49 168.5 2.0 2.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Zip PF02535.17 EJS41688.1 - 2.6 6.9 4.8 4.5 6.1 3.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Shugoshin_N PF07558.6 EJS41689.1 - 3.9e-14 52.0 4.4 3.9e-14 52.0 3.1 2.4 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EJS41689.1 - 1.4e-10 40.4 2.0 1.4e-10 40.4 1.4 3.3 4 0 0 4 4 4 1 Shugoshin C terminus TSC22 PF01166.13 EJS41689.1 - 0.048 13.6 0.6 0.18 11.7 0.4 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family Syntaxin-18_N PF10496.4 EJS41690.1 - 3.7e-18 65.1 1.8 3.7e-18 65.1 1.3 1.9 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EJS41690.1 - 0.015 14.9 7.2 0.048 13.3 5.0 2.0 1 0 0 1 1 1 0 SNARE domain DUF2120 PF09893.4 EJS41690.1 - 3.8 7.4 13.5 0.56 10.1 2.4 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) GTP_EFTU PF00009.22 EJS41691.1 - 4.4e-28 97.9 0.0 7.9e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EJS41691.1 - 6.2e-07 29.3 0.2 2.1e-06 27.6 0.2 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EJS41691.1 - 0.00018 21.3 1.4 0.084 12.6 0.1 2.9 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 EJS41691.1 - 0.015 14.5 0.1 0.081 12.1 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 EJS41691.1 - 0.14 12.6 2.2 0.5 10.8 0.0 3.1 3 1 0 3 3 3 0 Miro-like protein Kin17_mid PF10357.4 EJS41692.1 - 4.2e-32 110.4 0.0 6.2e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EJS41692.1 - 6.8e-06 26.0 2.7 1.5e-05 24.9 1.9 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EJS41692.1 - 0.00021 21.3 2.9 0.00041 20.4 2.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EJS41692.1 - 0.045 13.8 2.9 0.051 13.6 0.2 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) TFIID_90kDa PF04494.10 EJS41692.1 - 0.094 12.7 0.5 0.2 11.7 0.4 1.5 1 1 0 1 1 1 0 WD40 associated region in TFIID subunit Spore_III_AB PF09548.5 EJS41692.1 - 0.13 12.0 0.8 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF2175 PF09943.4 EJS41692.1 - 3.3 7.8 5.3 1.7 8.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2H2 PF00096.21 EJS41692.1 - 3.7 8.0 5.3 1.4 9.4 1.4 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zip PF02535.17 EJS41693.1 - 2.9e-50 171.1 8.4 5.8e-48 163.5 5.8 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Fun_ATP-synt_8 PF05933.8 EJS41693.1 - 2.7 8.0 6.3 14 5.7 0.0 3.7 4 0 0 4 4 4 0 Fungal ATP synthase protein 8 (A6L) DUF3336 PF11815.3 EJS41694.1 - 5.9e-40 136.1 3.9 9.8e-40 135.4 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EJS41694.1 - 3.5e-25 89.1 0.0 8.2e-25 87.9 0.0 1.6 2 0 0 2 2 2 1 Patatin-like phospholipase rpo30_N PF12410.3 EJS41694.1 - 0.0047 16.5 0.1 0.23 11.1 0.1 2.7 2 0 0 2 2 2 1 Poxvirus DNA dependent RNA polymerase 30kDa subunit Imm25 PF15571.1 EJS41694.1 - 0.0053 16.8 0.1 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 Immunity protein 25 Whi5 PF08528.6 EJS41695.1 - 1.1e-10 40.8 0.1 1.7e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Whi5 like Plasmodium_Vir PF05795.6 EJS41695.1 - 0.11 11.6 5.6 0.18 10.9 3.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PBP1_TM PF14812.1 EJS41695.1 - 0.54 10.5 7.6 1.3 9.3 0.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 EJS41695.1 - 4.8 6.3 7.5 0.23 10.7 0.4 1.9 2 0 0 2 2 2 0 NOA36 protein Abhydrolase_6 PF12697.2 EJS41696.1 - 2.2e-27 96.4 0.0 2.7e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EJS41696.1 - 8.2e-06 25.6 0.0 4.2e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EJS41696.1 - 4.3e-05 23.1 0.0 0.0002 20.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EJS41696.1 - 0.00083 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 EJS41696.1 - 0.013 15.1 0.0 0.029 13.9 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein OST3_OST6 PF04756.8 EJS41697.1 - 1.8e-38 131.6 11.8 3.5e-38 130.6 8.2 1.5 1 0 0 1 1 1 1 OST3 / OST6 family C2 PF00168.25 EJS41698.1 - 2.2e-55 184.4 3.8 8e-18 64.0 0.0 4.5 4 0 0 4 4 4 4 C2 domain Ion_trans PF00520.26 EJS41699.1 - 0.0013 17.9 19.0 0.033 13.4 13.1 2.5 1 1 0 1 1 1 1 Ion transport protein DUF106 PF01956.11 EJS41699.1 - 0.033 13.7 2.9 1.1 8.7 0.1 2.6 2 0 0 2 2 2 0 Integral membrane protein DUF106 Ras PF00071.17 EJS41700.1 - 2e-60 202.8 0.0 2.4e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS41700.1 - 2.6e-19 69.8 0.0 4.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS41700.1 - 1.3e-17 63.5 0.1 1.5e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EJS41700.1 - 1.6e-09 37.2 0.0 2.1e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EJS41700.1 - 2.3e-06 27.1 0.0 4.4e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EJS41700.1 - 1.8e-05 24.6 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EJS41700.1 - 0.063 12.9 0.0 0.092 12.4 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase PP2C PF00481.16 EJS41701.1 - 4.9e-55 186.6 0.0 8.9e-55 185.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Mem_trans PF03547.13 EJS41702.1 - 9e-105 350.1 2.3 1.1e-104 349.8 1.6 1.0 1 0 0 1 1 1 1 Membrane transport protein AMP-binding PF00501.23 EJS41703.1 - 3.7e-34 117.8 0.0 7.2e-13 47.7 0.0 5.1 5 0 0 5 5 5 5 AMP-binding enzyme DMAP_binding PF06464.6 EJS41703.1 - 1e-20 74.3 3.2 3.6e-20 72.6 2.2 2.1 1 0 0 1 1 1 1 DMAP1-binding Domain Arf PF00025.16 EJS41704.1 - 3.3e-72 241.3 0.2 3.8e-72 241.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EJS41704.1 - 2.3e-15 56.2 0.0 2.9e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EJS41704.1 - 1.3e-13 50.4 1.8 2.6e-09 36.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EJS41704.1 - 1.9e-13 50.0 0.0 2.4e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EJS41704.1 - 1.6e-11 43.8 0.0 1.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EJS41704.1 - 7.6e-09 36.1 0.0 1.1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EJS41704.1 - 4e-05 23.5 0.0 5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EJS41704.1 - 0.083 11.9 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Rib_5-P_isom_A PF06026.9 EJS41705.1 - 1.3e-55 187.3 0.0 1.6e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EJS41705.1 - 0.0012 18.5 0.0 0.075 12.6 0.0 2.2 1 1 0 1 1 1 1 DeoR C terminal sensor domain DUF4526 PF15029.1 EJS41706.1 - 0.53 9.8 2.0 0.85 9.1 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) Glyco_transf_15 PF01793.11 EJS41707.1 - 2.2e-144 480.4 16.4 2.7e-144 480.1 11.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Mito_carr PF00153.22 EJS41708.1 - 2.2e-61 203.5 5.8 1e-21 76.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pentaxin PF00354.12 EJS41708.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Pentaxin family Ras PF00071.17 EJS41709.1 - 3.9e-56 188.9 0.2 5.6e-56 188.3 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS41709.1 - 2.1e-21 76.5 0.2 4.4e-21 75.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EJS41709.1 - 1.4e-08 34.2 0.1 1.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EJS41709.1 - 9.9e-06 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EJS41709.1 - 1.1e-05 25.0 0.1 7.7e-05 22.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EJS41709.1 - 0.0074 15.5 0.2 0.019 14.2 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_25 PF13481.1 EJS41709.1 - 0.072 12.4 0.1 0.12 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain DAD PF02109.11 EJS41710.1 - 1.4e-38 131.3 6.6 1.7e-38 131.1 4.6 1.1 1 0 0 1 1 1 1 DAD family Pox_Ag35 PF03286.9 EJS41711.1 - 3 7.3 7.5 4.5 6.7 5.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SNARE PF05739.14 EJS41712.1 - 2.7e-16 58.9 6.5 2.7e-16 58.9 4.5 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 EJS41712.1 - 3.1e-09 36.7 2.1 3.1e-09 36.7 1.5 4.0 2 2 1 3 3 3 2 Syntaxin-like protein Synaptobrevin PF00957.16 EJS41712.1 - 5.1e-05 22.8 6.9 0.00015 21.2 1.1 2.6 2 0 0 2 2 2 1 Synaptobrevin Herpes_US9 PF06072.6 EJS41712.1 - 0.0088 15.8 0.3 0.017 14.9 0.2 1.4 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 DUF912 PF06024.7 EJS41712.1 - 0.016 15.2 1.2 0.016 15.2 0.9 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) T2SF PF00482.18 EJS41712.1 - 0.08 12.8 0.9 0.22 11.4 0.0 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F DUF1664 PF07889.7 EJS41712.1 - 6.9 6.4 10.7 0.53 10.0 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syja_N PF02383.13 EJS41713.1 - 9.6e-93 310.4 0.9 1.5e-92 309.8 0.6 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EJS41713.1 - 4.3e-25 89.0 0.0 1e-24 87.8 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family His_Phos_1 PF00300.17 EJS41714.1 - 5.4e-24 85.0 0.0 1.4e-23 83.7 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.4 EJS41714.1 - 2.3e-17 62.1 0.1 1.7e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 TFIIIC subunit HEAT PF02985.17 EJS41715.1 - 0.0065 16.4 0.1 4.5 7.6 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.3 EJS41715.1 - 0.045 13.0 0.2 0.38 10.0 0.0 2.3 2 0 0 2 2 2 0 CLASP N terminal DFF-C PF09033.5 EJS41715.1 - 0.054 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain zf-H2C2_2 PF13465.1 EJS41716.1 - 5.6e-22 76.8 23.5 1.5e-08 34.5 0.6 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 EJS41716.1 - 4.4e-20 70.7 24.2 2.6e-05 24.2 0.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS41716.1 - 1e-14 53.6 21.3 0.0016 18.5 0.2 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EJS41716.1 - 5e-06 26.4 13.8 0.14 12.3 0.1 4.6 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EJS41716.1 - 6.6e-05 22.9 15.0 0.0015 18.7 0.2 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EJS41716.1 - 0.00047 20.2 7.1 0.0059 16.7 0.3 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EJS41716.1 - 0.0037 17.1 13.6 0.23 11.4 0.2 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-CHCC PF10276.4 EJS41716.1 - 0.39 10.5 10.0 1.8 8.4 0.7 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-BED PF02892.10 EJS41716.1 - 3.1 7.6 17.5 3 7.6 0.4 4.3 1 1 2 4 4 4 0 BED zinc finger COX4 PF02936.9 EJS41717.1 - 0.063 13.0 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV TRAPP PF04051.11 EJS41718.1 - 7e-36 123.0 0.1 1.9e-35 121.6 0.0 1.8 2 1 0 2 2 2 1 Transport protein particle (TRAPP) component RNA_pol_Rpb1_5 PF04998.12 EJS41719.1 - 6.5e-98 327.3 0.0 9.7e-98 326.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EJS41719.1 - 6.6e-81 272.1 0.0 9.7e-81 271.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EJS41719.1 - 5.2e-70 234.6 0.0 1.1e-69 233.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EJS41719.1 - 1.8e-38 131.7 0.0 4.7e-38 130.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EJS41719.1 - 4e-31 106.9 0.0 9.4e-31 105.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.11 EJS41719.1 - 0.45 10.4 2.4 0.79 9.6 0.7 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain AAA PF00004.24 EJS41720.1 - 4.9e-42 143.2 0.0 1.1e-41 142.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EJS41720.1 - 2.1e-05 24.2 1.1 8.7e-05 22.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EJS41720.1 - 2.3e-05 24.3 0.0 0.00013 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EJS41720.1 - 3e-05 24.0 0.4 0.011 15.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EJS41720.1 - 0.00061 18.9 0.0 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EJS41720.1 - 0.0013 18.8 2.8 0.0071 16.4 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EJS41720.1 - 0.002 18.0 0.4 0.016 15.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 EJS41720.1 - 0.0036 16.5 0.1 0.032 13.4 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 EJS41720.1 - 0.0058 17.4 0.1 0.019 15.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 EJS41720.1 - 0.0072 15.2 0.0 0.015 14.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EJS41720.1 - 0.0099 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EJS41720.1 - 0.01 15.6 0.2 0.025 14.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EJS41720.1 - 0.012 14.7 0.1 0.038 13.1 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EJS41720.1 - 0.022 14.1 0.7 0.21 10.9 0.1 2.2 1 1 1 2 2 2 0 AAA domain BLOC1_2 PF10046.4 EJS41720.1 - 0.033 14.3 2.8 0.072 13.2 1.1 2.2 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_14 PF13173.1 EJS41720.1 - 0.033 14.0 0.2 0.093 12.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EJS41720.1 - 0.034 14.3 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 EJS41720.1 - 0.063 12.8 0.9 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EJS41720.1 - 0.068 12.7 0.4 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF1192 PF06698.6 EJS41720.1 - 0.11 12.3 2.0 0.27 11.0 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) KaiC PF06745.8 EJS41720.1 - 0.12 11.5 1.5 0.26 10.3 0.0 2.2 3 0 0 3 3 3 0 KaiC ThylakoidFormat PF11264.3 EJS41720.1 - 0.54 9.8 4.9 0.66 9.5 2.4 1.8 2 0 0 2 2 2 0 Thylakoid formation protein TLD PF07534.11 EJS41721.1 - 3.3e-29 101.6 0.2 2e-28 99.1 0.1 2.1 1 1 1 2 2 2 1 TLD RIO1 PF01163.17 EJS41722.1 - 2.8e-73 245.3 0.2 2.8e-73 245.3 0.2 2.7 3 0 0 3 3 3 1 RIO1 family APH PF01636.18 EJS41722.1 - 0.078 12.6 0.0 5.8 6.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nop14 PF04147.7 EJS41722.1 - 0.093 10.6 18.5 0.14 10.0 12.8 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.1 EJS41722.1 - 7 5.7 9.9 12 4.9 6.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Aldo_ket_red PF00248.16 EJS41723.1 - 7.6e-56 188.9 0.0 9.1e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Leo1 PF04004.8 EJS41724.1 - 1.2e-46 158.5 0.3 1.2e-46 158.5 0.2 3.3 3 1 0 3 3 3 1 Leo1-like protein Daxx PF03344.10 EJS41724.1 - 0.058 11.8 60.3 0.28 9.6 19.9 2.3 2 0 0 2 2 2 0 Daxx Family UCH PF00443.24 EJS41725.1 - 2.1e-63 213.9 4.9 5.2e-63 212.6 3.4 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EJS41725.1 - 3.1e-43 145.0 10.6 3.7e-20 71.0 0.4 4.7 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 EJS41725.1 - 1.2e-08 34.7 12.3 0.00028 20.4 1.0 3.3 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF4200 PF13863.1 EJS41725.1 - 0.092 12.6 6.1 0.2 11.6 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) COQ7 PF03232.8 EJS41726.1 - 6.9e-75 250.2 0.0 8.6e-75 249.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Tol_Tol_Ttg2 PF05494.7 EJS41726.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 Lipase_GDSL PF00657.17 EJS41727.1 - 2.2e-24 86.5 0.0 3e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EJS41727.1 - 5.5e-18 65.7 0.0 6.7e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RhoGAP PF00620.22 EJS41728.1 - 4.7e-46 156.1 0.5 1.4e-45 154.6 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EJS41728.1 - 2e-10 40.5 30.5 4.2e-06 26.7 8.0 2.6 2 0 0 2 2 2 2 LIM domain APG6 PF04111.7 EJS41728.1 - 2.4 7.1 21.3 0.024 13.7 8.8 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EJS41728.1 - 8.2 4.1 12.5 0.29 8.9 4.1 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family AIRC PF00731.15 EJS41729.1 - 7.5e-64 213.5 1.9 1.2e-63 212.8 1.3 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EJS41729.1 - 4.9e-63 211.5 0.0 1.2e-62 210.3 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EJS41729.1 - 3.3e-09 36.7 0.0 7e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 EJS41729.1 - 0.00015 20.9 0.0 0.00034 19.8 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.8 EJS41729.1 - 0.00043 19.7 0.0 0.006 15.9 0.0 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EJS41729.1 - 0.0037 16.5 0.0 0.0058 15.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 3HCDH_N PF02737.13 EJS41729.1 - 0.1 12.2 0.0 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mito_carr PF00153.22 EJS41730.1 - 3.5e-60 199.7 4.5 3.3e-21 74.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 EJS41731.1 - 1.1e-10 41.3 0.4 2.8e-10 39.9 0.2 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EJS41731.1 - 0.00018 20.8 10.6 0.00039 19.7 7.3 1.5 1 0 0 1 1 1 1 Vps5 C terminal like WSC PF01822.14 EJS41732.1 - 6e-13 48.5 17.5 6e-13 48.5 12.2 3.2 2 1 0 2 2 1 1 WSC domain DUF456 PF04306.8 EJS41732.1 - 0.005 16.8 0.3 0.0073 16.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) TMEM154 PF15102.1 EJS41732.1 - 0.006 16.3 1.5 0.006 16.3 1.0 2.5 1 1 1 2 2 1 1 TMEM154 protein family Bacteriocin_IIc PF10439.4 EJS41732.1 - 0.054 13.6 8.3 0.11 12.5 5.8 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF4514 PF14986.1 EJS41732.1 - 0.09 12.6 0.4 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) EphA2_TM PF14575.1 EJS41732.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gly-zipper_Omp PF13488.1 EJS41732.1 - 0.61 9.7 12.3 1.1 8.9 8.5 1.4 1 0 0 1 1 1 0 Glycine zipper Sec3_C PF09763.4 EJS41732.1 - 0.84 7.6 6.5 1.3 7.0 4.5 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 Gly-zipper_YMGG PF13441.1 EJS41732.1 - 1 8.9 11.4 1.6 8.3 7.9 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF566 PF04484.7 EJS41732.1 - 3.4 7.0 23.4 5.6 6.3 16.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) Beta-APP PF03494.8 EJS41732.1 - 5.4 6.5 7.3 13 5.3 5.0 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) SRP1_TIP1 PF00660.12 EJS41733.1 - 3.7e-35 119.8 0.7 1.4e-34 117.9 0.5 2.0 1 0 0 1 1 1 1 Seripauperin and TIP1 family DUF963 PF06131.6 EJS41733.1 - 0.0034 16.6 21.1 0.0034 16.6 14.6 9.7 2 2 7 9 9 9 4 Schizosaccharomyces pombe repeat of unknown function (DUF963) Pox_A28 PF04584.9 EJS41733.1 - 0.031 14.1 1.2 0.056 13.3 0.8 1.4 1 0 0 1 1 1 0 Poxvirus A28 family C1_1 PF00130.17 EJS41733.1 - 0.15 11.7 1.8 0.33 10.7 1.0 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SRP1_TIP1 PF00660.12 EJS41734.1 - 3.1e-35 120.1 0.4 8.7e-35 118.6 0.3 1.7 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.14 EJS41734.1 - 1.3e-07 30.6 7.5 1.3e-07 30.6 5.2 3.5 2 0 0 2 2 2 1 Yeast PIR protein repeat Spc42p PF11544.3 EJS41734.1 - 0.036 14.0 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Spindle pole body component Spc42p TFIIA PF03153.8 EJS41734.1 - 0.84 9.4 10.9 1 9.1 7.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hex_IIIa PF02455.11 EJS41734.1 - 2.9 6.4 11.4 23 3.5 6.8 2.0 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) SRP-alpha_N PF04086.8 EJS41734.1 - 3.4 6.9 7.6 4.5 6.5 5.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.4 EJS41734.1 - 8.4 4.5 22.1 11 4.1 15.3 1.1 1 0 0 1 1 1 0 Transmembrane protein ABC2_membrane PF01061.19 EJS41735.1 - 2.2e-66 223.0 60.3 8.2e-36 123.1 18.6 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EJS41735.1 - 1e-29 103.5 0.0 3.5e-15 56.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EJS41735.1 - 7.6e-28 96.1 18.1 4e-25 87.4 0.2 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EJS41735.1 - 2.2e-12 46.6 46.3 5.2e-06 25.7 9.9 3.3 2 1 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 EJS41735.1 - 4.2e-05 22.7 0.1 8.5e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EJS41735.1 - 0.0016 18.7 0.0 0.0049 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EJS41735.1 - 0.0027 17.7 0.6 0.0027 17.7 0.4 4.7 3 2 1 4 4 4 1 AAA domain cobW PF02492.14 EJS41735.1 - 0.0058 16.0 0.1 0.0098 15.3 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EJS41735.1 - 0.0082 15.3 0.5 0.58 9.3 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EJS41735.1 - 0.02 14.9 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EJS41735.1 - 0.021 15.1 1.9 0.028 14.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EJS41735.1 - 0.027 14.4 0.1 0.056 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EJS41735.1 - 0.054 13.0 0.5 0.13 11.8 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EJS41735.1 - 0.084 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EJS41735.1 - 0.094 12.6 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.1 EJS41735.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NTPase_P4 PF11602.3 EJS41735.1 - 0.29 10.0 0.1 0.47 9.4 0.1 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 B56 PF01603.15 EJS41736.1 - 3.2e-148 493.6 15.9 9.1e-141 469.1 7.3 2.3 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Cpn10 PF00166.16 EJS41738.1 - 2e-26 91.7 0.4 2.2e-26 91.5 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF2611 PF11022.3 EJS41739.1 - 4.2e-22 78.0 1.3 7.3e-22 77.2 0.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) Ribosomal_S30AE PF02482.14 EJS41739.1 - 0.034 14.5 0.1 0.036 14.4 0.1 1.2 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein RNA_Me_trans PF04252.8 EJS41740.1 - 4.4e-90 300.3 0.1 5e-90 300.1 0.1 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase WD40 PF00400.27 EJS41741.1 - 7.6e-13 47.7 5.1 2e-05 24.3 0.0 5.0 5 1 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EJS41741.1 - 5.9e-05 21.9 0.7 0.1 11.3 0.0 2.3 2 1 0 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 EJS41741.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EJS41741.1 - 0.091 11.0 0.0 0.18 10.0 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain TPR_11 PF13414.1 EJS41742.1 - 4.2e-56 186.4 34.2 3.1e-17 61.9 0.0 6.4 4 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 EJS41742.1 - 1.1e-47 157.7 20.8 6.5e-08 31.8 0.2 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EJS41742.1 - 1.3e-33 112.1 22.7 1.3e-06 27.8 0.2 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EJS41742.1 - 8.4e-24 83.3 18.0 5.6e-09 35.8 1.2 5.8 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EJS41742.1 - 2.6e-21 73.7 20.9 4.5e-05 22.9 0.3 9.1 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EJS41742.1 - 1.4e-18 67.0 14.3 0.0013 19.3 0.0 7.1 3 3 5 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 EJS41742.1 - 1.6e-17 62.3 10.1 0.051 14.2 0.0 9.1 5 2 3 9 9 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EJS41742.1 - 3.2e-15 54.6 15.6 0.0027 17.3 0.1 7.4 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EJS41742.1 - 3.9e-14 51.5 15.3 0.0089 16.1 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EJS41742.1 - 6.4e-14 52.0 21.0 0.00013 22.2 0.4 7.2 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.1 EJS41742.1 - 1e-08 34.9 2.7 0.00014 21.6 0.0 5.3 5 3 2 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 EJS41742.1 - 3.7e-07 30.1 16.0 0.02 15.0 0.1 4.4 3 1 2 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EJS41742.1 - 3.4e-05 24.0 20.3 1.9 9.1 0.0 8.4 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 EJS41742.1 - 0.00028 20.7 1.1 0.6 10.1 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3808 PF10300.4 EJS41742.1 - 0.00032 19.4 4.3 0.00042 19.0 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) Pterin_4a PF01329.14 EJS41742.1 - 0.032 13.9 0.9 6.8 6.5 0.1 3.0 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase MAS20 PF02064.10 EJS41742.1 - 0.037 13.9 2.0 2 8.3 0.0 3.7 2 1 2 4 4 4 0 MAS20 protein import receptor TPR_20 PF14561.1 EJS41742.1 - 0.24 11.5 14.3 0.25 11.4 0.5 4.7 4 2 2 6 6 6 0 Tetratricopeptide repeat XPC-binding PF09280.6 EJS41742.1 - 0.56 9.7 8.9 0.071 12.5 2.5 2.3 2 1 0 2 2 2 0 XPC-binding domain SHNi-TPR PF10516.4 EJS41742.1 - 0.77 9.0 10.3 4 6.7 0.0 5.7 8 0 0 8 8 8 0 SHNi-TPR Fis1_TPR_C PF14853.1 EJS41742.1 - 0.79 9.6 7.5 23 4.9 0.0 5.5 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 EJS41742.1 - 1.6 9.3 6.6 1.6 9.4 0.3 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat bZIP_1 PF00170.16 EJS41743.1 - 2.5e-11 43.3 12.7 3.8e-11 42.7 8.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 EJS41743.1 - 0.0062 16.2 1.3 0.0062 16.2 0.9 1.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper HAUS6_N PF14661.1 EJS41743.1 - 0.0086 15.4 1.4 0.011 15.1 1.0 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Hemagglutinin PF00509.13 EJS41743.1 - 0.029 12.5 0.9 0.039 12.1 0.6 1.1 1 0 0 1 1 1 0 Haemagglutinin Glutaredoxin2_C PF04399.8 EJS41743.1 - 0.23 11.0 1.7 0.41 10.2 1.2 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_Maf PF03131.12 EJS41743.1 - 0.4 10.9 8.5 0.79 10.0 5.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 EJS41743.1 - 5.9 6.8 16.0 1.2 8.9 8.7 1.7 2 0 0 2 2 2 0 Basic region leucine zipper PalH PF08733.5 EJS41744.1 - 1.1e-84 284.3 25.1 1.4e-84 283.9 17.4 1.1 1 0 0 1 1 1 1 PalH/RIM21 Caa3_CtaG PF09678.5 EJS41744.1 - 0.33 9.8 8.5 0.14 11.0 0.4 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Metallothi_Euk2 PF12809.2 EJS41745.1 - 3e-09 37.1 48.4 3.7e-09 36.8 33.5 1.1 1 0 0 1 1 1 1 Eukaryotic metallothionein HLH PF00010.21 EJS41746.1 - 1.7e-19 69.2 0.3 1.7e-19 69.2 0.2 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Syntaxin_2 PF14523.1 EJS41747.1 - 8.1e-21 73.9 13.0 3.7e-20 71.8 3.5 2.3 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.14 EJS41747.1 - 1.1e-19 69.9 3.7 1.1e-19 69.9 2.6 2.9 4 0 0 4 4 4 1 SNARE domain Synaptobrevin PF00957.16 EJS41747.1 - 0.0027 17.2 1.9 0.0027 17.2 1.3 2.7 4 0 0 4 4 4 1 Synaptobrevin MCPsignal PF00015.16 EJS41747.1 - 0.023 14.2 18.2 0.46 9.9 6.8 2.4 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4056 PF13265.1 EJS41747.1 - 0.035 13.0 0.3 0.062 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) Herpes_US9 PF06072.6 EJS41747.1 - 0.055 13.3 0.2 0.092 12.5 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 V-SNARE PF05008.10 EJS41747.1 - 0.06 13.5 7.4 0.18 12.0 0.3 3.2 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF2077 PF09850.4 EJS41747.1 - 0.088 12.1 0.7 0.27 10.5 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) BLOC1_2 PF10046.4 EJS41747.1 - 0.12 12.5 13.7 1.2 9.2 1.2 3.9 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EJS41747.1 - 0.17 10.3 17.7 0.24 9.8 11.9 1.4 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EJS41747.1 - 0.29 10.2 10.1 2.6 7.1 0.3 2.1 1 1 1 2 2 2 0 KaiC RNA_pol_A_CTD PF03118.10 EJS41747.1 - 0.44 9.9 3.0 1.1 8.7 0.1 2.7 3 0 0 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain Sigma_reg_N PF13800.1 EJS41747.1 - 1.5 8.9 6.6 0.99 9.4 2.8 2.1 2 0 0 2 2 1 0 Sigma factor regulator N-terminal ISG65-75 PF11727.3 EJS41747.1 - 2.4 7.1 13.4 2.9 6.8 5.5 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF4200 PF13863.1 EJS41747.1 - 2.4 8.1 14.4 0.93 9.4 0.1 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) Syntaxin PF00804.20 EJS41747.1 - 2.5 8.3 19.9 0.97 9.6 5.7 3.2 2 1 1 3 3 3 0 Syntaxin FAD_binding_6 PF00970.19 EJS41748.1 - 5.5e-07 29.6 0.0 4.5e-06 26.7 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain CK_II_beta PF01214.13 EJS41749.1 - 1.1e-72 243.4 0.1 1.3e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Lactamase_B PF00753.22 EJS41750.1 - 2.1e-23 83.0 0.1 2.9e-23 82.5 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EJS41750.1 - 7.3e-05 22.3 0.1 9.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CUE PF02845.11 EJS41751.1 - 7.3e-11 41.3 0.0 1.5e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 CUE domain DEAD PF00270.24 EJS41755.1 - 6e-36 123.4 1.1 4.5e-35 120.6 0.2 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS41755.1 - 1e-26 92.5 0.1 2e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EJS41755.1 - 5.4e-05 23.0 1.6 0.00024 20.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EJS41755.1 - 0.0042 17.0 0.0 0.037 13.9 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_22 PF13401.1 EJS41755.1 - 0.014 15.5 0.2 0.084 13.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.1 EJS41755.1 - 0.016 14.8 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EJS41755.1 - 0.027 13.4 0.4 0.052 12.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CMS1 PF14617.1 EJS41755.1 - 0.25 10.3 0.0 0.25 10.3 0.0 2.9 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit XRN_N PF03159.13 EJS41757.1 - 4.7e-109 363.3 0.6 5.3e-108 359.8 0.0 2.8 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus zf-AN1 PF01428.11 EJS41758.1 - 1.7e-09 37.3 12.1 3.6e-09 36.3 8.4 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger DUF3827 PF12877.2 EJS41758.1 - 0.26 9.3 3.2 0.3 9.1 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Transp_Tc5_C PF04236.10 EJS41758.1 - 0.32 11.2 7.1 0.55 10.4 4.9 1.5 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain SR-25 PF10500.4 EJS41758.1 - 0.4 10.1 12.3 0.022 14.2 5.0 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Calc_CGRP_IAPP PF00214.14 EJS41758.1 - 4.1 7.4 8.5 7.4 6.6 2.1 2.8 2 1 1 3 3 3 0 Calcitonin / CGRP / IAPP family NOB1_Zn_bind PF08772.6 EJS41759.1 - 2.6e-27 94.4 0.9 7.7e-27 92.9 0.6 1.9 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EJS41759.1 - 6.7 6.6 16.6 49 3.9 11.5 2.4 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator SGS PF05002.10 EJS41760.1 - 2.4e-29 100.9 0.4 9.3e-29 99.0 0.3 2.1 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EJS41760.1 - 1.5e-16 60.7 2.4 5.3e-16 58.9 0.3 2.3 2 0 0 2 2 2 1 CS domain TPR_2 PF07719.12 EJS41760.1 - 0.0029 17.4 1.3 0.14 12.1 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EJS41760.1 - 0.0039 16.8 2.1 0.67 9.6 0.1 2.3 2 0 0 2 2 2 2 TPR repeat Apc3 PF12895.2 EJS41760.1 - 0.0044 17.1 3.4 0.076 13.1 0.4 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EJS41760.1 - 0.028 15.1 0.1 14 6.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EJS41760.1 - 0.052 13.1 2.0 0.32 10.6 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EJS41760.1 - 0.088 13.4 0.0 21 6.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EJS41760.1 - 0.22 11.3 2.6 0.24 11.2 0.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MAP65_ASE1 PF03999.7 EJS41761.1 - 1e-178 595.8 36.1 1.3e-178 595.4 25.0 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) zf-DHHC PF01529.15 EJS41762.1 - 2.6e-32 111.5 15.0 2.6e-32 111.5 10.4 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase HlyIII PF03006.15 EJS41763.1 - 5.5e-53 179.6 20.4 6.5e-53 179.4 14.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3671 PF12420.3 EJS41763.1 - 1.6 8.7 9.6 9.2 6.3 2.2 3.2 1 1 1 2 2 2 0 Protein of unknown function Cyclin PF08613.6 EJS41764.1 - 5.9e-39 133.8 1.3 1e-38 133.0 0.9 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EJS41764.1 - 0.024 14.2 0.1 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain DNA_pol_A_exo1 PF01612.15 EJS41765.1 - 2.7e-48 163.7 0.4 6.1e-48 162.6 0.3 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EJS41765.1 - 2.2e-22 79.1 4.4 1.3e-21 76.7 1.1 2.7 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EJS41765.1 - 4e-11 42.4 0.0 8.8e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Alg6_Alg8 PF03155.10 EJS41766.1 - 2.4e-177 590.5 30.7 2.8e-177 590.2 21.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Peptidase_S8 PF00082.17 EJS41767.1 - 2.4e-54 184.3 3.3 3.4e-54 183.8 2.3 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EJS41767.1 - 4.4e-12 46.4 0.0 9.7e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DNA_ligase_A_M PF01068.16 EJS41768.1 - 4.4e-52 176.3 0.0 7.6e-52 175.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain BRCT PF00533.21 EJS41768.1 - 3.9e-13 49.3 0.5 2.8e-07 30.5 0.1 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_N PF04675.9 EJS41768.1 - 5e-13 49.2 0.0 8.7e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EJS41768.1 - 4.7e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EJS41768.1 - 0.0025 17.5 1.5 0.3 10.7 0.0 2.9 3 0 0 3 3 3 2 mRNA capping enzyme, catalytic domain Fve PF09259.6 EJS41768.1 - 0.091 12.6 0.0 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 Fungal immunomodulatory protein Fve TPR_11 PF13414.1 EJS41769.1 - 2.6e-22 78.2 9.1 2.3e-17 62.4 2.1 3.0 1 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EJS41769.1 - 1e-18 66.0 6.3 8.7e-07 28.2 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EJS41769.1 - 1.1e-16 59.2 8.0 1.7e-05 24.3 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EJS41769.1 - 7.9e-11 42.3 10.3 7e-06 26.5 0.2 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EJS41769.1 - 4.1e-09 36.2 6.0 4.6e-07 29.6 0.4 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EJS41769.1 - 2.2e-08 34.0 0.2 0.029 14.9 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EJS41769.1 - 1e-07 31.5 3.4 0.00093 19.2 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EJS41769.1 - 1.8e-07 31.3 4.6 0.0023 18.2 0.2 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EJS41769.1 - 3.8e-06 26.2 8.8 0.024 14.4 0.1 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EJS41769.1 - 2.8e-05 23.6 2.5 0.83 9.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 EJS41769.1 - 0.00011 22.4 0.1 0.0012 19.1 0.0 2.2 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 EJS41769.1 - 0.00071 19.4 1.0 2.2 8.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EJS41769.1 - 0.0011 19.3 3.2 0.061 13.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EJS41769.1 - 0.0081 15.9 0.1 0.21 11.4 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EJS41769.1 - 0.02 14.7 1.6 3.4 7.6 0.1 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 EJS41769.1 - 0.031 14.4 2.2 0.23 11.6 1.5 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 EJS41769.1 - 0.2 11.4 3.0 1 9.1 0.8 3.0 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) MIT PF04212.13 EJS41769.1 - 1.1 9.1 13.5 0.31 10.9 0.2 3.9 3 2 1 4 4 3 0 MIT (microtubule interacting and transport) domain GTP_EFTU PF00009.22 EJS41771.1 - 3.1e-35 121.3 3.3 2.4e-34 118.4 2.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EJS41771.1 - 3.3e-24 84.8 0.6 1.2e-23 83.1 0.4 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EJS41771.1 - 8.6e-10 38.6 0.4 5e-05 23.3 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EJS41771.1 - 2e-08 33.7 0.0 7.3e-08 31.9 0.0 2.1 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EJS41771.1 - 2.9e-06 27.2 0.2 9e-06 25.6 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EJS41771.1 - 1.6e-05 25.4 0.8 3.7e-05 24.2 0.1 2.0 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EJS41771.1 - 0.008 16.0 5.2 1.6 8.5 0.0 3.6 4 1 1 5 5 5 2 Dynamin family Ras PF00071.17 EJS41771.1 - 0.024 14.0 0.0 0.077 12.3 0.0 1.9 1 0 0 1 1 1 0 Ras family DUF2095 PF09868.4 EJS41771.1 - 0.046 13.4 0.2 0.32 10.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) PDCD2_C PF04194.8 EJS41772.1 - 5.6e-39 133.3 1.4 1.3e-37 128.8 0.0 2.8 2 1 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain DUF1247 PF06851.6 EJS41772.1 - 0.38 10.4 3.9 2.8 7.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1247) RNB PF00773.14 EJS41773.1 - 1.5e-94 316.9 0.0 2.3e-94 316.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EJS41773.1 - 6.8e-14 52.1 0.2 1.7e-13 50.8 0.2 1.6 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 EJS41773.1 - 0.016 14.7 0.0 0.048 13.1 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain AA_permease PF00324.16 EJS41774.1 - 1.6e-117 392.8 43.8 1.9e-117 392.5 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS41774.1 - 1.9e-32 112.3 45.9 2.4e-32 112.0 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease YMF19 PF02326.10 EJS41774.1 - 2.7 8.6 5.7 4.4 7.9 0.1 3.1 3 0 0 3 3 3 0 Plant ATP synthase F0 SUR7 PF06687.7 EJS41775.1 - 2.8e-20 72.8 16.7 4.3e-20 72.1 11.6 1.3 1 0 0 1 1 1 1 SUR7/PalI family PAT1 PF09770.4 EJS41775.1 - 0.96 7.6 33.3 1.3 7.2 23.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EMP70 PF02990.11 EJS41775.1 - 1.3 7.3 6.6 0.72 8.2 2.9 1.5 1 1 0 1 1 1 0 Endomembrane protein 70 FLO_LFY PF01698.11 EJS41775.1 - 2 7.1 9.0 0.17 10.7 2.9 1.5 2 0 0 2 2 2 0 Floricaula / Leafy protein Histone PF00125.19 EJS41777.1 - 1.7e-22 79.3 0.1 2.1e-22 78.9 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EJS41777.1 - 0.00018 21.5 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PLA2_B PF01735.13 EJS41778.1 - 8.1e-229 759.7 1.1 1e-228 759.4 0.7 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain RTC PF01137.16 EJS41779.1 - 8.3e-61 204.6 0.0 9.6e-61 204.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EJS41779.1 - 6.8e-29 99.9 0.0 1.2e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Topoisom_I_N PF02919.10 EJS41781.1 - 4.6e-101 336.5 0.4 4.6e-101 336.5 0.2 3.8 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EJS41781.1 - 1.8e-85 285.8 1.5 1.8e-85 285.8 1.0 2.9 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EJS41781.1 - 3.2e-33 113.2 0.8 3.2e-33 113.2 0.5 2.4 2 0 0 2 2 2 1 C-terminal topoisomerase domain Peptidase_M49 PF03571.10 EJS41782.1 - 9.3e-228 756.7 0.0 1.2e-227 756.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 His_Phos_1 PF00300.17 EJS41783.1 - 3.5e-41 140.9 0.1 1.6e-40 138.8 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-C3HC4_4 PF15227.1 EJS41784.1 - 1.2e-09 37.8 10.4 1.2e-09 37.8 7.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EJS41784.1 - 2.3e-08 33.5 9.5 2.3e-08 33.5 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EJS41784.1 - 6.1e-08 32.5 9.5 6.1e-08 32.5 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EJS41784.1 - 3e-07 30.1 9.2 3e-07 30.1 6.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EJS41784.1 - 3.3e-07 29.8 5.8 3.3e-07 29.8 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EJS41784.1 - 1.1e-06 28.1 2.8 1.1e-06 28.1 2.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EJS41784.1 - 5e-06 26.1 8.4 5e-06 26.1 5.8 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-ribbon_3 PF13248.1 EJS41784.1 - 0.0016 17.5 2.3 0.012 14.8 0.3 2.7 2 0 0 2 2 2 1 zinc-ribbon domain HypA PF01155.14 EJS41784.1 - 0.0054 16.4 5.3 0.11 12.1 0.1 2.3 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EJS41784.1 - 0.0055 16.4 11.1 0.37 10.6 0.5 2.7 2 1 1 3 3 3 3 Double zinc ribbon zf-rbx1 PF12678.2 EJS41784.1 - 0.017 15.1 3.9 0.017 15.1 2.7 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger zinc_ribbon_2 PF13240.1 EJS41784.1 - 0.023 14.1 3.2 0.6 9.6 0.6 3.4 2 1 0 2 2 2 0 zinc-ribbon domain zf-Apc11 PF12861.2 EJS41784.1 - 0.029 14.1 1.9 0.029 14.1 1.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 EJS41784.1 - 0.053 13.5 16.4 0.059 13.3 1.7 3.8 3 1 0 3 3 3 0 zinc-finger NinF PF05810.7 EJS41784.1 - 0.057 13.2 0.4 0.057 13.2 0.3 2.8 3 0 0 3 3 1 0 NinF protein zf-CHY PF05495.7 EJS41784.1 - 0.07 13.3 8.8 7 6.8 0.1 3.2 2 1 1 3 3 3 0 CHY zinc finger zf-RING_4 PF14570.1 EJS41784.1 - 2.2 7.9 17.9 1.1 8.8 5.1 3.1 2 2 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.2 EJS41784.1 - 3.3 7.6 8.3 4.4 7.1 0.1 3.5 4 0 0 4 4 3 0 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.7 EJS41784.1 - 5.2 6.9 10.2 5.5 6.8 0.2 2.7 2 1 0 2 2 2 0 zinc-ribbons zf-MIZ PF02891.15 EJS41784.1 - 5.5 6.5 16.1 0.071 12.6 5.2 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DUF164 PF02591.10 EJS41784.1 - 6.8 6.6 5.9 1.1 9.1 0.0 2.7 2 2 0 2 2 1 0 Putative zinc ribbon domain Reovirus_M2 PF05993.7 EJS41785.1 - 0.068 10.9 0.3 0.069 10.9 0.2 1.0 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) SAM_decarbox PF01536.11 EJS41786.1 - 1.1e-124 415.5 3.6 1.2e-124 415.3 2.5 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase L_protein_N PF15518.1 EJS41786.1 - 0.046 13.1 0.9 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 L protein N-terminus Tbf5 PF06331.7 EJS41786.1 - 0.23 11.2 2.2 5.3 6.9 0.1 3.1 4 0 0 4 4 4 0 Transcription factor TFIIH complex subunit Tfb5 Med15_fungi PF05397.7 EJS41787.1 - 2.5e-39 133.7 5.6 2.5e-39 133.7 3.9 7.3 4 2 2 6 6 6 1 Mediator complex subunit 15 GSH_synth_ATP PF03917.12 EJS41788.1 - 9.6e-137 455.4 0.1 1.1e-136 455.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EJS41788.1 - 2.2e-37 127.3 0.2 4e-37 126.5 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase CppA_C PF14507.1 EJS41788.1 - 0.21 11.7 2.0 0.37 11.0 0.2 2.3 3 0 0 3 3 3 0 CppA C-terminal Pkinase PF00069.20 EJS41789.1 - 1.4e-60 204.6 0.2 2.4e-60 203.8 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41789.1 - 1.8e-23 82.9 0.0 3.1e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS41789.1 - 2.6e-09 36.4 0.0 4.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.1 EJS41789.1 - 0.0021 18.4 0.0 0.98 9.8 0.0 2.9 2 0 0 2 2 2 2 PAS domain Kdo PF06293.9 EJS41789.1 - 0.0029 16.6 0.1 0.0052 15.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS41789.1 - 0.012 15.3 0.2 0.025 14.3 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family PAS PF00989.19 EJS41789.1 - 0.022 14.5 0.0 2.3 8.0 0.0 2.6 2 0 0 2 2 2 0 PAS fold HhH-GPD PF00730.20 EJS41791.1 - 2.2e-19 69.7 0.0 4e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EJS41791.1 - 0.00012 21.6 0.0 0.00071 19.1 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 EJS41791.1 - 0.044 13.9 2.4 0.1 12.8 1.7 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Exo_endo_phos PF03372.18 EJS41792.1 - 1.8e-16 60.8 0.1 2.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.17 EJS41793.1 - 1.7e-18 65.9 2.8 2.8e-15 55.7 0.1 4.4 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS41793.1 - 7.7e-14 51.4 0.3 3.6e-11 42.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS41793.1 - 2e-12 46.7 0.6 5e-07 29.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EJS41793.1 - 0.01 15.6 0.0 0.35 10.6 0.0 2.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ribosomal_S19 PF00203.16 EJS41794.1 - 7.9e-32 108.7 0.3 1.8e-31 107.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 EJS41795.1 - 1.3e-25 89.6 13.3 1.5e-25 89.3 9.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Joubert PF15392.1 EJS41795.1 - 0.16 11.2 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated Proteasome PF00227.21 EJS41796.1 - 1.9e-56 190.3 0.0 2.5e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EJS41796.1 - 6.1e-14 51.0 0.1 1.4e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature APC_CDC26 PF10471.4 EJS41796.1 - 0.094 13.4 5.5 0.19 12.4 3.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF775 PF05603.7 EJS41798.1 - 1.4e-59 201.0 0.1 1.7e-59 200.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Toxin_56 PF15534.1 EJS41799.1 - 0.06 13.8 0.0 0.23 12.0 0.0 1.9 1 0 0 1 1 1 0 Putative toxin 56 SYF2 PF08231.7 EJS41799.1 - 0.11 12.6 3.5 0.24 11.5 2.4 1.7 1 0 0 1 1 1 0 SYF2 splicing factor PSD4 PF07631.6 EJS41799.1 - 0.17 12.2 2.3 4.2 7.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) Glyco_hydro_72 PF03198.9 EJS41800.1 - 6.4e-144 478.7 10.0 9.4e-144 478.1 6.9 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EJS41800.1 - 1.1e-05 24.4 0.1 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EJS41800.1 - 6.1e-05 22.3 0.3 0.00079 18.7 0.2 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Nop14 PF04147.7 EJS41800.1 - 0.0027 15.7 6.5 0.0034 15.3 4.5 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4614 PF15391.1 EJS41800.1 - 0.079 12.7 20.7 0.18 11.5 14.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.4 EJS41800.1 - 0.18 10.6 17.7 0.27 10.0 12.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.5 EJS41800.1 - 0.86 8.6 19.1 1.2 8.1 13.2 1.2 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.8 EJS41800.1 - 1.2 7.6 7.1 1.8 7.0 4.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.9 EJS41800.1 - 1.2 7.0 12.6 1.8 6.5 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.6 EJS41800.1 - 1.5 6.8 27.3 2.6 6.0 18.9 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF572 PF04502.8 EJS41800.1 - 4.1 6.5 14.5 6.3 5.9 10.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Na_trans_assoc PF06512.8 EJS41800.1 - 5.9 6.7 13.4 10 5.9 9.3 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated LETM1 PF07766.8 EJS41801.1 - 3.9e-106 353.9 7.0 6.4e-106 353.2 4.9 1.3 1 0 0 1 1 1 1 LETM1-like protein UCH PF00443.24 EJS41801.1 - 0.26 10.3 6.7 0.019 14.1 0.8 1.8 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase TOM13 PF08219.6 EJS41802.1 - 2e-29 101.1 0.0 2.5e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 HRXXH PF13933.1 EJS41803.1 - 4.4e-81 271.9 0.3 5.2e-81 271.7 0.2 1.0 1 0 0 1 1 1 1 Putative peptidase family GH-E PF14410.1 EJS41803.1 - 0.036 14.2 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Epimerase PF01370.16 EJS41804.1 - 8.1e-15 54.8 0.0 1.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EJS41804.1 - 9.7e-14 50.7 0.0 1.2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EJS41804.1 - 5.6e-08 32.9 0.1 1.2e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EJS41804.1 - 1.2e-05 24.4 0.0 5.7e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EJS41804.1 - 0.00016 21.6 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EJS41804.1 - 0.00088 18.2 0.1 0.0026 16.6 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EJS41804.1 - 0.0096 15.1 0.0 0.59 9.3 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EJS41804.1 - 0.042 12.7 0.0 0.25 10.1 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain DXP_redisom_C PF08436.7 EJS41804.1 - 0.068 13.0 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal DUF4109 PF13397.1 EJS41804.1 - 0.18 12.2 0.1 0.38 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4109) Spt20 PF12090.3 EJS41805.1 - 8.5e-57 191.4 6.7 8.5e-57 191.4 4.6 3.3 3 1 0 3 3 3 1 Spt20 family PEX11 PF05648.9 EJS41806.1 - 1.4e-63 214.1 5.0 1.6e-63 213.9 3.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sld5 PF05916.6 EJS41807.1 - 3.2e-15 56.3 0.1 4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein RRM_5 PF13893.1 EJS41808.1 - 1.7e-10 40.5 1.1 4.5e-10 39.2 0.8 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS41808.1 - 0.00024 21.0 1.2 0.0019 18.1 0.3 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EJS41808.1 - 0.00038 20.0 3.2 0.001 18.6 1.2 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DMRL_synthase PF00885.14 EJS41809.1 - 3.9e-44 149.8 0.1 4.7e-44 149.5 0.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase UBA_e1_C PF09358.5 EJS41810.1 - 0.021 14.9 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain LCM PF04072.9 EJS41811.1 - 3.2e-30 105.0 0.0 5.9e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EJS41811.1 - 1.4e-17 63.1 0.9 4.6e-09 35.9 0.0 5.4 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EJS41811.1 - 5.1e-14 51.7 3.8 0.00017 21.6 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 EJS41811.1 - 4.1e-10 39.3 0.2 0.16 11.9 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 EJS41811.1 - 6e-10 39.0 1.4 0.0034 17.4 0.0 4.9 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EJS41811.1 - 1.8e-09 36.9 3.3 0.012 15.1 0.0 6.6 7 0 0 7 7 7 2 Kelch motif Kelch_2 PF07646.10 EJS41811.1 - 2.2e-08 33.5 1.3 0.032 14.0 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Glu-tRNAGln PF02686.10 EJS41811.1 - 0.019 14.7 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Aminotran_3 PF00202.16 EJS41812.1 - 6.9e-115 383.5 0.1 8.6e-115 383.1 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III PucR PF07905.6 EJS41812.1 - 0.063 12.8 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family Beta_elim_lyase PF01212.16 EJS41812.1 - 0.091 11.8 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase IF4E PF01652.13 EJS41813.1 - 1.4e-56 190.5 0.1 1.8e-56 190.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MFS_1 PF07690.11 EJS41814.1 - 9.9e-24 83.6 39.0 2.2e-20 72.7 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EJS41814.1 - 1.5 8.9 10.8 0.33 11.0 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) 6PF2K PF01591.13 EJS41815.1 - 9.6e-78 260.2 3.9 1.4e-77 259.7 2.7 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_18 PF13238.1 EJS41815.1 - 0.00045 20.5 0.1 0.0012 19.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.5 EJS41815.1 - 0.00079 18.7 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EJS41815.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain C5-epim_C PF06662.8 EJS41815.1 - 0.0032 16.7 0.1 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus AAA_17 PF13207.1 EJS41815.1 - 0.004 17.9 0.0 0.011 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF234 PF03008.9 EJS41815.1 - 0.072 13.2 1.3 0.26 11.4 0.2 2.3 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function AAA_22 PF13401.1 EJS41815.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain zf-rbx1 PF12678.2 EJS41816.1 - 3.1e-32 110.4 13.8 4.2e-32 110.0 9.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EJS41816.1 - 5.9e-17 61.2 10.1 8.5e-17 60.7 7.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EJS41816.1 - 3.8e-07 29.8 11.8 3e-06 26.9 8.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EJS41816.1 - 0.0019 17.7 11.9 0.019 14.5 8.3 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EJS41816.1 - 0.016 15.2 2.0 0.016 15.2 1.4 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EJS41816.1 - 0.046 13.2 2.9 0.087 12.3 2.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 EJS41816.1 - 0.06 13.0 10.2 2.6 7.7 7.1 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EJS41816.1 - 0.19 11.6 6.9 0.19 11.5 0.3 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EJS41816.1 - 0.2 11.3 7.7 0.2 11.3 2.9 2.6 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.1 EJS41816.1 - 0.55 10.0 10.3 4.2 7.1 7.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 EJS41816.1 - 1.3 9.0 9.7 7.2 6.6 6.9 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Glyco_hydro_72 PF03198.9 EJS41817.1 - 8.5e-138 458.6 4.0 1e-137 458.3 2.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EJS41817.1 - 0.00016 21.0 0.6 0.0016 17.7 0.1 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CorA PF01544.13 EJS41819.1 - 4e-41 140.9 3.4 3.2e-25 88.7 0.0 2.2 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein DUF2231 PF09990.4 EJS41819.1 - 0.028 14.7 0.9 0.054 13.8 0.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF4199 PF13858.1 EJS41819.1 - 0.07 13.0 0.5 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Cu_amine_oxidN1 PF07833.6 EJS41819.1 - 0.075 13.3 0.0 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Copper amine oxidase N-terminal domain UPF0220 PF05255.6 EJS41820.1 - 4.3e-69 230.9 1.0 4.8e-69 230.8 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pkinase PF00069.20 EJS41821.1 - 1.9e-53 181.2 0.0 2.5e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41821.1 - 1.4e-24 86.5 0.0 1.9e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS41821.1 - 0.00068 18.6 0.0 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EJS41821.1 - 0.0067 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EJS41821.1 - 0.0076 15.0 0.3 0.0076 15.0 0.2 1.6 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EJS41821.1 - 0.0096 15.0 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4024 PF13216.1 EJS41821.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) RNaseH_C PF09293.5 EJS41821.1 - 0.053 13.4 0.8 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 T4 RNase H, C terminal TRM13 PF05206.9 EJS41822.1 - 8e-77 257.9 1.6 1.2e-76 257.4 1.1 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 EJS41822.1 - 1.3e-11 43.6 4.6 3.1e-11 42.4 3.2 1.7 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 EJS41822.1 - 4.2e-10 39.1 2.3 8.9e-10 38.0 1.6 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger UPF0020 PF01170.13 EJS41823.1 - 1.3e-14 54.1 0.0 2.5e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EJS41823.1 - 6.2e-07 29.4 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EJS41823.1 - 0.005 16.3 0.0 0.21 11.0 0.0 2.4 2 1 0 2 2 2 1 DNA methylase MethyltransfD12 PF02086.10 EJS41823.1 - 0.0093 15.4 2.2 1.4 8.2 0.0 3.2 2 1 0 3 3 3 2 D12 class N6 adenine-specific DNA methyltransferase Cons_hypoth95 PF03602.10 EJS41823.1 - 0.089 12.1 0.0 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 RRM_1 PF00076.17 EJS41824.1 - 1.1e-36 124.2 0.3 8.9e-19 66.9 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS41824.1 - 7e-32 109.2 0.0 9.8e-16 57.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS41824.1 - 1.1e-10 41.1 0.0 0.0005 19.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EJS41824.1 - 0.014 14.8 0.3 3.5 7.2 0.0 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain CAML PF14963.1 EJS41824.1 - 2.5 7.3 9.5 5.2 6.3 6.6 1.6 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand PAT1 PF09770.4 EJS41824.1 - 6.9 4.7 40.9 0.16 10.1 13.5 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Nramp PF01566.13 EJS41825.1 - 3.8e-93 312.1 12.9 7.5e-93 311.1 8.9 1.4 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein MFS_1 PF07690.11 EJS41826.1 - 1.4e-27 96.3 35.8 1.4e-27 96.3 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GCR1_C PF12550.3 EJS41827.1 - 9.6e-25 86.2 0.3 2e-24 85.2 0.2 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes RmuC PF02646.11 EJS41827.1 - 0.048 12.5 0.6 0.16 10.7 0.4 1.9 2 0 0 2 2 2 0 RmuC family DUF802 PF05650.6 EJS41827.1 - 0.088 12.9 1.1 0.14 12.3 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF802) SM-ATX PF14438.1 EJS41827.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.9 1 1 1 2 2 2 0 Ataxin 2 SM domain NTP_transf_2 PF01909.18 EJS41828.1 - 6.3e-17 61.6 0.2 2.8e-16 59.5 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EJS41828.1 - 5e-13 48.7 0.0 2.8e-12 46.3 0.0 2.4 2 0 0 2 2 2 1 Cid1 family poly A polymerase DNA_pol_B_palm PF14792.1 EJS41828.1 - 0.0022 18.0 0.0 0.0063 16.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm RD3 PF14473.1 EJS41828.1 - 0.061 12.7 1.8 0.13 11.7 1.3 1.5 1 0 0 1 1 1 0 RD3 protein Pkinase PF00069.20 EJS41829.1 - 3.7e-63 213.0 0.1 7.4e-63 212.1 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41829.1 - 2e-50 171.2 0.1 3.3e-50 170.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EJS41829.1 - 1.6e-21 76.4 0.1 5.3e-21 74.7 0.1 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 EJS41829.1 - 4.5e-10 39.6 0.4 2e-09 37.5 0.3 2.1 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EJS41829.1 - 6.2e-07 28.6 0.0 1.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EJS41829.1 - 1.7e-06 28.2 0.4 1.7e-06 28.2 0.3 2.5 3 0 0 3 3 3 1 Pleckstrin homology domain Cellulase-like PF12876.2 EJS41829.1 - 0.07 13.5 0.2 0.73 10.3 0.0 2.6 3 0 0 3 3 3 0 Sugar-binding cellulase-like DUF2102 PF09875.4 EJS41829.1 - 0.11 11.9 0.1 3.3 7.2 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2102) APH PF01636.18 EJS41829.1 - 0.19 11.4 0.1 0.58 9.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family ubiquitin PF00240.18 EJS41830.1 - 2.9e-12 45.7 0.3 5.4e-12 44.9 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EJS41830.1 - 2.9e-05 23.9 0.3 6e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CLU_N PF15044.1 EJS41830.1 - 0.00049 20.1 0.1 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term Rad60-SLD PF11976.3 EJS41830.1 - 0.002 17.7 0.1 0.0047 16.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Erf4 PF10256.4 EJS41831.1 - 1.6e-21 76.3 0.0 2e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Apolipoprotein PF01442.13 EJS41832.1 - 0.0015 18.0 15.4 0.0031 17.0 10.7 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EJS41832.1 - 0.0051 17.1 12.2 0.011 16.0 8.1 1.7 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) NCD2 PF04905.8 EJS41832.1 - 0.094 12.5 4.9 0.083 12.6 2.8 1.4 1 1 0 1 1 1 0 NAB conserved region 2 (NCD2) OmpH PF03938.9 EJS41832.1 - 0.11 12.3 21.4 0.13 12.1 14.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Herpes_pp85 PF04637.7 EJS41832.1 - 0.12 10.6 3.4 0.13 10.4 2.4 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Nbl1_Borealin_N PF10444.4 EJS41832.1 - 0.22 10.9 1.4 13 5.2 0.0 2.5 1 1 0 2 2 2 0 Nbl1 / Borealin N terminal DUF2076 PF09849.4 EJS41832.1 - 0.28 11.2 8.2 0.4 10.7 5.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) HAUS-augmin3 PF14932.1 EJS41832.1 - 0.48 9.5 15.5 0.61 9.2 10.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.6 EJS41832.1 - 0.52 8.9 16.3 0.56 8.8 11.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.10 EJS41832.1 - 0.86 8.7 12.3 1 8.4 8.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.6 EJS41832.1 - 1 6.7 7.9 1.2 6.6 5.5 1.1 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.3 EJS41832.1 - 1.4 6.1 19.3 1.6 5.9 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.8 EJS41832.1 - 2.6 7.0 11.6 2.9 6.8 8.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein ATP11 PF06644.6 EJS41832.1 - 2.6 7.4 15.4 3.2 7.1 10.7 1.2 1 0 0 1 1 1 0 ATP11 protein CCDC84 PF14968.1 EJS41832.1 - 3.1 7.2 11.4 3.3 7.1 7.9 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 TBCA PF02970.11 EJS41832.1 - 3.3 7.8 17.8 2.2 8.4 2.3 2.3 1 1 1 2 2 2 0 Tubulin binding cofactor A DUF4407 PF14362.1 EJS41832.1 - 4.2 6.2 18.5 5.5 5.8 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Carboxyl_trans PF01039.17 EJS41832.1 - 4.3 5.5 8.3 4.6 5.4 5.7 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain Draxin PF15550.1 EJS41832.1 - 4.5 6.8 9.8 5.4 6.5 6.8 1.0 1 0 0 1 1 1 0 Draxin AAA_13 PF13166.1 EJS41832.1 - 6 5.1 19.9 6.7 5.0 13.8 1.0 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.6 EJS41832.1 - 6.2 4.9 23.2 7.4 4.7 16.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF572 PF04502.8 EJS41832.1 - 6.5 5.8 17.8 7 5.7 12.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) FLO_LFY PF01698.11 EJS41832.1 - 6.6 5.4 14.0 8 5.1 9.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein MAT1 PF06391.8 EJS41832.1 - 7.3 6.1 17.5 7.7 6.0 12.1 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Mitofilin PF09731.4 EJS41832.1 - 8.7 4.8 22.5 9.8 4.6 15.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WSC PF01822.14 EJS41833.1 - 1.5e-10 40.8 11.8 1.5e-10 40.8 8.2 3.4 2 1 0 2 2 2 1 WSC domain Syndecan PF01034.15 EJS41833.1 - 2.2e-05 24.0 0.0 5.9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 EJS41833.1 - 3.7e-05 22.9 0.6 3.7e-05 22.9 0.4 3.1 3 0 0 3 3 3 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EJS41833.1 - 0.012 15.9 0.1 0.058 13.7 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EJS41833.1 - 0.022 14.3 0.1 0.022 14.3 0.1 2.1 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF605 PF04652.11 EJS41833.1 - 0.031 13.6 26.1 0.058 12.7 18.1 1.5 1 0 0 1 1 1 0 Vta1 like Ni_hydr_CYTB PF01292.15 EJS41833.1 - 0.11 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 RCR PF12273.3 EJS41833.1 - 0.21 12.1 0.1 0.21 12.1 0.0 2.5 2 2 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red MtrF PF09472.5 EJS41833.1 - 0.26 10.5 3.1 0.49 9.6 2.1 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Sugar_tr PF00083.19 EJS41835.1 - 5.7e-148 493.2 31.2 6.9e-148 492.9 21.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS41835.1 - 7e-28 97.3 35.2 3.9e-26 91.5 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EJS41835.1 - 3.1e-06 25.6 2.2 3.1e-06 25.6 1.5 2.0 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EJS41835.1 - 0.00053 18.2 0.6 0.00053 18.2 0.4 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector DUF1673 PF07895.6 EJS41835.1 - 1.1 8.7 13.3 0.017 14.6 2.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) PTS_2-RNA PF01885.11 EJS41836.1 - 6.8e-57 191.7 0.1 9.1e-57 191.3 0.1 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PARP PF00644.15 EJS41836.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain HlyIII PF03006.15 EJS41837.1 - 2.6e-25 89.1 21.6 3e-25 88.9 15.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Methyltransf_23 PF13489.1 EJS41838.1 - 6.2e-21 74.7 0.0 9.9e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS41838.1 - 3.4e-13 50.1 0.0 1.4e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EJS41838.1 - 5.1e-12 45.6 0.0 8.2e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EJS41838.1 - 2.9e-11 43.7 0.0 6.1e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EJS41838.1 - 1.1e-10 41.8 0.0 2.9e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EJS41838.1 - 4.2e-08 33.4 0.0 2.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EJS41838.1 - 1.5e-07 30.8 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EJS41838.1 - 1.4e-06 27.8 0.0 2.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EJS41838.1 - 5.7e-06 25.6 0.0 8.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 EJS41838.1 - 1.9e-05 24.1 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EJS41838.1 - 0.00036 20.2 0.0 0.00063 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EJS41838.1 - 0.00046 19.6 0.1 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EJS41838.1 - 0.00046 20.1 0.0 0.00096 19.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EJS41838.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.13 EJS41838.1 - 0.024 13.7 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EJS41838.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UvrD_C PF13361.1 EJS41839.1 - 1.6e-65 221.8 1.0 2.6e-65 221.2 0.0 1.8 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EJS41839.1 - 9.2e-39 133.5 5.5 1.1e-19 70.8 2.3 2.9 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EJS41839.1 - 7.6e-12 45.2 0.0 2.2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EJS41839.1 - 1.5e-11 44.3 0.2 7.9e-05 22.2 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EJS41839.1 - 2.7e-09 36.9 0.2 6.1e-08 32.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EJS41839.1 - 1.6e-08 34.1 0.0 4.5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EJS41839.1 - 0.0074 15.3 5.7 0.22 10.4 0.0 3.5 4 1 1 5 5 5 2 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EJS41839.1 - 0.069 12.6 0.2 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase Rep_fac_C PF08542.6 EJS41840.1 - 6.4e-18 64.5 1.7 3.3e-17 62.2 0.1 2.6 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EJS41840.1 - 3e-14 53.0 0.1 1.2e-11 44.5 0.1 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EJS41840.1 - 7.3e-13 48.8 0.0 1.5e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EJS41840.1 - 3.3e-09 35.9 0.1 6.1e-06 25.1 0.0 2.4 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EJS41840.1 - 1.9e-07 31.2 0.0 1.2e-05 25.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EJS41840.1 - 3e-07 30.3 0.0 5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EJS41840.1 - 3.2e-06 27.3 0.2 0.0015 18.6 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EJS41840.1 - 1.1e-05 24.6 0.1 4.5e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EJS41840.1 - 7.2e-05 22.3 0.0 0.00016 21.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EJS41840.1 - 0.0001 21.9 0.0 0.00021 20.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EJS41840.1 - 0.00025 20.6 0.2 0.11 11.9 0.0 2.3 1 1 1 2 2 2 2 AAA-like domain NTPase_1 PF03266.10 EJS41840.1 - 0.00058 19.6 0.1 0.013 15.1 0.0 2.3 1 1 0 2 2 2 1 NTPase Mg_chelatase PF01078.16 EJS41840.1 - 0.0016 17.6 0.1 0.023 13.8 0.1 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EJS41840.1 - 0.0016 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DNA_pol3_delta PF06144.8 EJS41840.1 - 0.0029 17.1 0.1 0.0056 16.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EJS41840.1 - 0.0069 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain ArgK PF03308.11 EJS41840.1 - 0.013 14.3 0.1 0.1 11.3 0.0 2.3 2 1 1 3 3 3 0 ArgK protein NB-ARC PF00931.17 EJS41840.1 - 0.013 14.3 0.0 0.026 13.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.1 EJS41840.1 - 0.026 14.1 0.1 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EJS41840.1 - 0.063 12.4 0.0 0.13 11.4 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 DEAD PF00270.24 EJS41840.1 - 0.064 12.7 0.2 0.49 9.8 0.1 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_31 PF13614.1 EJS41840.1 - 0.077 12.9 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EJS41840.1 - 0.091 12.4 0.1 0.34 10.5 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EJS41840.1 - 0.1 12.8 0.1 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Med28 PF11594.3 EJS41840.1 - 0.11 12.7 0.9 7.8 6.7 0.1 3.1 3 1 0 3 3 3 0 Mediator complex subunit 28 RNA_helicase PF00910.17 EJS41840.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.7 1 1 0 1 1 1 0 RNA helicase PQ-loop PF04193.9 EJS41841.1 - 3.4e-41 138.6 14.6 1.4e-20 72.5 2.0 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF1301 PF06979.7 EJS41841.1 - 0.59 10.2 4.3 12 6.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1301) MutS_V PF00488.16 EJS41843.1 - 2.1e-98 328.4 0.1 4e-98 327.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EJS41843.1 - 1.2e-34 119.8 2.4 2.9e-34 118.6 0.1 2.3 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EJS41843.1 - 2.7e-25 88.9 2.3 3e-25 88.8 0.2 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EJS41843.1 - 2.2e-18 66.2 1.0 2.2e-18 66.2 0.7 2.2 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 EJS41843.1 - 5.7e-10 39.2 0.1 2.7e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 MutS domain I RsbRD_N PF14361.1 EJS41843.1 - 0.083 13.3 0.1 0.29 11.5 0.1 1.9 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Fungal_trans PF04082.13 EJS41844.1 - 1.9e-37 128.5 4.3 1.9e-37 128.5 3.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS41844.1 - 5.4e-09 35.8 13.3 1.1e-08 34.8 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mit_KHE1 PF10173.4 EJS41844.1 - 0.28 11.0 5.0 0.23 11.2 1.5 2.4 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Thioredoxin PF00085.15 EJS41845.1 - 1.6e-11 43.7 0.2 5.2e-11 42.1 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EJS41845.1 - 0.0038 17.3 0.1 0.013 15.5 0.1 1.9 1 0 0 1 1 1 1 Thioredoxin-like Ribosomal_L38e PF01781.13 EJS41845.1 - 0.065 12.9 0.0 5.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L38e protein family Syntaxin_2 PF14523.1 EJS41845.1 - 0.29 11.1 3.4 2 8.4 0.1 2.3 1 1 1 2 2 2 0 Syntaxin-like protein DUF3337 PF11816.3 EJS41846.1 - 3.2e-86 289.7 13.6 4.4e-86 289.2 6.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 EJS41846.1 - 2.5e-06 27.1 10.2 0.14 12.0 0.3 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat ADH_N PF08240.7 EJS41847.1 - 7e-30 102.9 0.4 2e-29 101.5 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EJS41847.1 - 1.4e-29 102.2 1.8 2e-29 101.7 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EJS41847.1 - 0.0001 23.1 0.2 0.00023 22.0 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ATG19_autophagy PF12744.2 EJS41848.1 - 4e-74 248.8 0.4 6.7e-74 248.1 0.3 1.3 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding RasGAP PF00616.14 EJS41849.1 - 1.5e-41 142.2 1.8 1.5e-41 142.2 1.3 3.1 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RNase_T PF00929.19 EJS41850.1 - 6.2e-29 101.3 0.0 9.2e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EJS41850.1 - 0.0025 17.3 0.0 0.0092 15.4 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease DUF2611 PF11022.3 EJS41851.1 - 4.2e-25 87.6 0.0 4.5e-25 87.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Brix PF04427.13 EJS41852.1 - 2.4e-40 138.2 0.2 3.6e-40 137.6 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF468 PF04318.7 EJS41852.1 - 0.057 13.9 0.4 0.19 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF468) NatB_MDM20 PF09797.4 EJS41853.1 - 8.2e-75 251.7 16.2 8.2e-75 251.7 11.2 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit ABC_tran PF00005.22 EJS41854.1 - 5.4e-51 172.4 0.5 1.9e-24 86.5 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EJS41854.1 - 4.9e-40 136.9 35.1 1.1e-25 90.0 9.7 2.5 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 EJS41854.1 - 4.7e-18 66.1 6.9 5.1e-06 26.6 0.1 4.5 3 1 1 4 4 4 4 AAA domain DUF258 PF03193.11 EJS41854.1 - 6.1e-10 38.5 1.2 8.8e-05 21.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 EJS41854.1 - 4.4e-09 35.8 3.7 9.2e-06 25.0 0.1 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EJS41854.1 - 7.7e-09 35.7 0.2 4.7e-05 23.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EJS41854.1 - 8e-09 35.0 4.5 0.0012 18.0 0.0 4.4 4 0 0 4 4 4 3 AAA ATPase domain AAA_17 PF13207.1 EJS41854.1 - 1.4e-07 32.3 0.0 0.024 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EJS41854.1 - 2e-07 31.1 0.1 0.021 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EJS41854.1 - 4.1e-07 29.5 0.0 0.0023 17.3 0.0 4.0 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.1 EJS41854.1 - 7.6e-07 29.4 0.0 0.016 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EJS41854.1 - 1.9e-06 27.2 3.6 0.049 13.1 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 EJS41854.1 - 1.5e-05 24.6 1.6 0.055 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain NACHT PF05729.7 EJS41854.1 - 1.5e-05 24.6 0.0 0.019 14.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 EJS41854.1 - 0.00013 22.0 0.1 0.02 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EJS41854.1 - 0.00034 20.3 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase MMR_HSR1 PF01926.18 EJS41854.1 - 0.00035 20.5 1.3 0.19 11.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EJS41854.1 - 0.00046 19.8 0.1 0.064 13.0 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EJS41854.1 - 0.00047 20.2 1.3 1.5 9.0 0.0 3.6 3 0 0 3 3 3 1 RNA helicase KAP_NTPase PF07693.9 EJS41854.1 - 0.00051 19.1 0.0 0.26 10.2 0.0 2.5 2 0 0 2 2 2 1 KAP family P-loop domain SbcCD_C PF13558.1 EJS41854.1 - 0.00052 19.8 0.5 1.9 8.4 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EJS41854.1 - 0.00087 18.2 1.0 0.1 11.4 0.2 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 EJS41854.1 - 0.0017 18.7 9.6 0.029 14.7 0.1 3.9 3 1 1 4 4 3 1 AAA domain MobB PF03205.9 EJS41854.1 - 0.0023 17.6 1.1 1.3 8.7 0.2 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EJS41854.1 - 0.0023 17.8 0.0 3.5 7.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EJS41854.1 - 0.0024 17.3 2.6 0.015 14.8 0.2 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family NTPase_1 PF03266.10 EJS41854.1 - 0.0028 17.3 0.3 15 5.2 0.0 3.5 3 0 0 3 3 3 0 NTPase AAA PF00004.24 EJS41854.1 - 0.0035 17.5 0.1 3.7 7.7 0.0 3.5 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EJS41854.1 - 0.0053 16.4 0.3 1.5 8.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.10 EJS41854.1 - 0.0063 15.2 0.2 0.021 13.4 0.0 1.8 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_33 PF13671.1 EJS41854.1 - 0.0066 16.3 0.1 2.9 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EJS41854.1 - 0.011 15.3 0.3 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EJS41854.1 - 0.013 15.0 0.6 0.35 10.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 EJS41854.1 - 0.016 15.6 0.8 8.7 6.8 0.1 2.9 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 EJS41854.1 - 0.019 14.4 3.3 0.99 8.8 0.8 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EJS41854.1 - 0.034 13.0 0.7 2.9 6.6 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.13 EJS41854.1 - 0.052 13.1 1.1 5.3 6.5 0.1 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.12 EJS41854.1 - 0.061 13.1 8.3 0.46 10.2 0.0 3.5 4 1 0 4 4 3 0 Domain of unknown function DUF87 AAA_24 PF13479.1 EJS41854.1 - 0.15 11.5 1.6 11 5.5 0.3 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EJS41854.1 - 0.24 10.4 1.2 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.4 EJS41854.1 - 0.26 9.8 0.7 0.9 8.0 0.3 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Dynamin_N PF00350.18 EJS41854.1 - 4.2 7.1 7.0 9.1 6.0 0.6 2.8 2 0 0 2 2 2 0 Dynamin family PCI PF01399.22 EJS41856.1 - 6.6e-19 68.1 0.3 2.7e-18 66.2 0.1 2.2 2 0 0 2 2 2 1 PCI domain HTH_IclR PF09339.5 EJS41856.1 - 0.092 12.3 0.0 13 5.4 0.0 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain Nuf2 PF03800.9 EJS41857.1 - 1.4e-49 167.8 2.4 1.4e-49 167.8 1.7 2.0 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 EJS41857.1 - 0.05 12.7 9.2 0.017 14.3 4.0 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein PspB PF06667.7 EJS41857.1 - 0.26 11.2 4.0 13 5.8 0.1 3.3 2 1 1 3 3 3 0 Phage shock protein B HLH PF00010.21 EJS41858.1 - 5.9e-18 64.3 0.0 8.5e-18 63.8 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MbeD_MobD PF04899.7 EJS41858.1 - 0.08 12.8 0.2 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 MbeD/MobD like Exo_endo_phos PF03372.18 EJS41859.1 - 1.3e-19 71.1 0.0 1.6e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EJS41859.1 - 0.06 12.9 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Inositol_P PF00459.20 EJS41860.1 - 2.7e-64 217.0 0.1 1.6e-63 214.5 0.0 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family Adap_comp_sub PF00928.16 EJS41861.1 - 2.5e-78 262.8 0.6 2.5e-78 262.8 0.4 1.8 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EJS41861.1 - 0.00058 19.5 0.1 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Pribosyl_synth PF14572.1 EJS41862.1 - 4.9e-42 143.7 1.2 2.4e-41 141.4 0.9 2.0 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EJS41862.1 - 7.7e-34 115.9 0.0 2.9e-33 114.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EJS41862.1 - 2.1e-12 46.8 0.0 5e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain NAD_Gly3P_dh_N PF01210.18 EJS41863.1 - 6.2e-53 178.7 0.0 9.6e-53 178.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EJS41863.1 - 1.1e-48 164.7 0.1 1.6e-48 164.2 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EJS41863.1 - 0.032 14.6 0.1 0.53 10.7 0.1 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EJS41863.1 - 0.11 12.7 0.0 1.5 9.1 0.0 2.3 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Arginosuc_synth PF00764.14 EJS41864.1 - 1e-164 548.2 0.0 1.2e-164 548.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EJS41864.1 - 4.7e-05 22.7 0.0 0.00011 21.5 0.0 1.6 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EJS41864.1 - 5.1e-05 22.8 0.0 7.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EJS41864.1 - 0.0013 17.4 0.0 0.0018 16.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Pyr_redox PF00070.22 EJS41865.1 - 5.4e-17 61.9 1.3 6.2e-13 48.9 0.0 2.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EJS41865.1 - 5.5e-15 55.7 0.0 9e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EJS41865.1 - 0.0003 20.5 0.5 0.24 11.1 0.1 2.4 1 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EJS41865.1 - 0.00044 19.2 1.3 0.14 11.0 0.8 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EJS41865.1 - 0.052 12.4 0.0 4.9 5.9 0.0 2.7 3 1 0 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EJS41865.1 - 0.12 10.9 1.0 0.61 8.6 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD-oxidase_C PF02913.14 EJS41866.1 - 2.6e-50 171.0 0.0 3.5e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EJS41866.1 - 1.4e-35 121.8 0.0 2.6e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ATPase-cat_bd PF12156.3 EJS41867.1 - 0.13 12.8 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Ribosom_S12_S23 PF00164.20 EJS41868.1 - 6e-44 148.3 1.4 7.5e-44 148.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S19 PF00203.16 EJS41869.1 - 1.5e-24 85.3 0.0 2.1e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Cation_efflux PF01545.16 EJS41870.1 - 8e-07 28.4 14.9 1.5e-06 27.5 9.2 2.0 2 1 0 2 2 2 1 Cation efflux family UbiA PF01040.13 EJS41871.1 - 5.7e-34 117.5 18.0 7.6e-34 117.0 12.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family GHMP_kinases_N PF00288.21 EJS41872.1 - 3.4e-10 39.8 1.2 1e-09 38.3 0.8 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain CbiA PF01656.18 EJS41872.1 - 0.0078 15.6 0.0 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Ins_allergen_rp PF06757.8 EJS41873.1 - 0.014 14.9 0.4 0.22 11.0 0.0 2.8 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification Trm112p PF03966.11 EJS41874.1 - 1.4e-21 76.6 0.0 1.7e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Ret_tiss PF10044.4 EJS41874.1 - 0.074 13.5 0.0 0.12 12.9 0.0 1.3 1 1 0 1 1 1 0 Retinal tissue protein CDC50 PF03381.10 EJS41875.1 - 1.4e-92 309.7 0.2 1.9e-92 309.3 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Mso1_Sec1_bdg PF14475.1 EJS41876.1 - 3e-19 68.1 0.1 5.8e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 DUF605 PF04652.11 EJS41876.1 - 0.27 10.6 8.9 0.3 10.4 6.1 1.1 1 0 0 1 1 1 0 Vta1 like MUG2_C PF08593.5 EJS41876.1 - 0.35 11.1 0.2 0.35 11.1 0.1 2.4 3 0 0 3 3 3 0 Meiotically up-regulated glycoproteins C-terminal Saccharop_dh PF03435.13 EJS41877.1 - 4.8e-127 424.1 0.0 5.5e-127 423.9 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EJS41877.1 - 2.6e-08 34.0 0.1 4.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EJS41877.1 - 6.3e-06 26.3 0.2 1.2e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 EJS41877.1 - 0.00069 20.0 0.1 0.0015 18.8 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.11 EJS41877.1 - 0.0064 16.8 0.2 0.012 16.0 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EJS41877.1 - 0.0065 16.7 0.1 0.019 15.2 0.1 1.7 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EJS41877.1 - 0.016 13.9 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EJS41877.1 - 0.033 13.4 0.1 0.05 12.8 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family IlvN PF07991.7 EJS41877.1 - 0.052 12.9 0.2 0.14 11.4 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Glyco_transf_21 PF13506.1 EJS41877.1 - 0.066 12.4 0.0 0.83 8.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 Epimerase PF01370.16 EJS41877.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NTF2 PF02136.15 EJS41878.1 - 4.5e-25 88.3 0.1 8.3e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EJS41878.1 - 0.0011 18.6 0.1 0.0026 17.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS41878.1 - 0.039 13.9 0.1 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2422 PF10337.4 EJS41878.1 - 2.6 6.7 4.7 4.2 6.0 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) CAF1 PF04857.15 EJS41879.1 - 1.3e-55 188.5 2.4 1.3e-55 188.5 1.7 1.5 2 0 0 2 2 2 1 CAF1 family ribonuclease TFIIA PF03153.8 EJS41879.1 - 0.53 10.1 25.7 0.17 11.7 14.9 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.17 EJS41880.1 - 0.0035 16.9 0.1 0.67 9.6 0.0 2.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD_3 PF13922.1 EJS41880.1 - 0.092 12.9 0.0 0.88 9.8 0.0 2.6 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx RRM_5 PF13893.1 EJS41880.1 - 0.11 12.3 1.8 0.52 10.2 0.1 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trypan_PARP PF05887.6 EJS41880.1 - 1.2 8.9 12.2 0.19 11.5 5.7 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.11 EJS41881.1 - 3.7e-32 111.4 19.9 3.7e-32 111.4 13.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Aminotran_3 PF00202.16 EJS41882.1 - 1.2e-84 284.0 0.0 1.9e-84 283.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EJS41882.1 - 0.047 12.8 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase BAG PF02179.11 EJS41882.1 - 0.11 12.5 0.1 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 BAG domain Mannosyl_trans3 PF11051.3 EJS41883.1 - 7.7e-58 195.9 0.4 1.1e-57 195.4 0.3 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative XET_C PF06955.7 EJS41883.1 - 0.0019 17.8 1.0 0.005 16.5 0.7 1.7 1 0 0 1 1 1 1 Xyloglucan endo-transglycosylase (XET) C-terminus Glyco_hydro_81 PF03639.8 EJS41884.1 - 0 1014.3 32.8 0 1014.3 22.8 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 Aldose_epim PF01263.15 EJS41885.1 - 5e-77 258.9 1.0 5.7e-77 258.7 0.7 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Grp1_Fun34_YaaH PF01184.14 EJS41886.1 - 2.6e-92 307.8 19.0 3e-92 307.6 13.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 EJS41886.1 - 0.74 8.7 5.2 0.29 10.1 1.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF373) RNA_pol_Rpc34 PF05158.7 EJS41887.1 - 4.1e-104 348.2 1.1 5e-104 347.9 0.7 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_36 PF13730.1 EJS41887.1 - 0.00046 20.2 0.2 0.099 12.7 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain Rrf2 PF02082.15 EJS41887.1 - 0.0047 17.0 0.9 0.017 15.2 0.1 2.1 2 0 0 2 2 2 1 Transcriptional regulator B-block_TFIIIC PF04182.7 EJS41887.1 - 0.0064 16.3 2.3 0.13 12.1 0.1 2.4 1 1 1 2 2 2 1 B-block binding subunit of TFIIIC TFIIE_alpha PF02002.12 EJS41887.1 - 0.11 12.0 1.1 1.6 8.2 0.0 2.6 3 0 0 3 3 3 0 TFIIE alpha subunit RPA_C PF08784.6 EJS41887.1 - 0.14 12.6 0.7 1.1 9.7 0.1 2.6 2 1 0 2 2 2 0 Replication protein A C terminal COX7a PF02238.10 EJS41888.1 - 0.13 12.0 0.1 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa VHS PF00790.14 EJS41889.1 - 2.2e-41 140.7 0.1 5.2e-41 139.5 0.1 1.6 1 0 0 1 1 1 1 VHS domain FYVE PF01363.16 EJS41889.1 - 4.8e-19 68.0 3.2 1.2e-18 66.7 2.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EJS41889.1 - 0.0045 16.4 13.7 0.15 11.7 0.5 3.8 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.11 EJS41889.1 - 0.0046 16.8 1.7 0.0046 16.8 1.2 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger Tis11B_N PF04553.7 EJS41889.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Tis11B like protein, N terminus zf-AN1 PF01428.11 EJS41889.1 - 0.78 9.6 14.4 0.051 13.4 6.2 1.8 2 0 0 2 2 2 0 AN1-like Zinc finger zf-RING_5 PF14634.1 EJS41889.1 - 0.9 9.3 9.3 0.61 9.8 2.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Autophagy_N PF03986.8 EJS41890.1 - 1e-43 148.6 0.3 1e-43 148.6 0.2 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EJS41890.1 - 8.4e-22 77.1 0.1 2.2e-21 75.8 0.1 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EJS41890.1 - 1.1e-13 50.0 2.8 1.9e-13 49.2 1.9 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal RXT2_N PF08595.6 EJS41890.1 - 0.002 17.9 3.4 0.38 10.5 1.2 2.6 3 0 0 3 3 3 2 RXT2-like, N-terminal LCAT PF02450.10 EJS41891.1 - 2.2e-151 504.3 0.1 2.7e-151 504.0 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EJS41891.1 - 0.0016 18.1 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EJS41891.1 - 0.0038 16.8 0.0 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 EJS41891.1 - 0.0092 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Lipase_2 PF01674.13 EJS41891.1 - 0.057 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) DUF900 PF05990.7 EJS41891.1 - 0.084 12.1 0.0 0.48 9.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Whi5 PF08528.6 EJS41892.1 - 1.4e-10 40.4 2.6 2.7e-10 39.5 1.8 1.5 1 0 0 1 1 1 1 Whi5 like Med9 PF07544.8 EJS41893.1 - 4e-27 93.7 0.7 7.6e-27 92.8 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Mvb12 PF09452.5 EJS41893.1 - 0.07 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 Wx5_PLAF3D7 PF09688.5 EJS41893.1 - 0.15 11.9 1.1 0.25 11.3 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) HA2 PF04408.18 EJS41894.1 - 4.3e-17 62.0 2.0 6e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EJS41894.1 - 1.4e-15 57.0 0.0 4.8e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EJS41894.1 - 9.5e-14 51.0 0.0 2.7e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EJS41894.1 - 6e-07 29.1 0.2 2.5e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EJS41894.1 - 0.00041 20.5 0.3 0.0016 18.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain T2SE PF00437.15 EJS41894.1 - 0.0037 16.1 0.0 0.0085 15.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EJS41894.1 - 0.0062 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_14 PF13173.1 EJS41894.1 - 0.033 14.0 0.2 2.2 8.2 0.1 3.2 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EJS41894.1 - 0.034 13.2 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.22 EJS41894.1 - 0.04 14.2 0.2 0.04 14.2 0.1 2.4 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 EJS41894.1 - 0.099 12.4 0.0 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain NAD_binding_2 PF03446.10 EJS41894.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AAA_30 PF13604.1 EJS41894.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EJS41895.1 - 1.4e-64 217.2 0.0 2.1e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EJS41895.1 - 3e-33 114.7 0.0 4.5e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EJS41895.1 - 1.3e-09 38.8 0.0 4.1e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EJS41895.1 - 8e-08 32.6 0.3 2.9e-06 27.6 0.0 3.2 2 1 2 4 4 4 1 AAA domain CPT PF07931.7 EJS41895.1 - 0.013 15.1 0.0 0.041 13.5 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 EJS41895.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EJS41895.1 - 0.036 13.9 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain SPX PF03105.14 EJS41896.1 - 7.2e-48 163.7 21.0 7.2e-48 163.7 14.6 1.9 2 0 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 EJS41896.1 - 7.8e-23 81.0 43.2 1e-22 80.6 30.0 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EJS41896.1 - 1.1e-11 44.0 44.2 4.3e-10 38.6 16.4 2.2 1 1 1 2 2 2 2 Citrate transporter RNA_pol_Rpo13 PF12136.3 EJS41897.1 - 0.013 15.1 1.2 0.02 14.5 0.9 1.3 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain ZF-HD_dimer PF04770.7 EJS41897.1 - 1.6 8.8 7.5 5 7.2 0.5 2.9 3 0 0 3 3 3 0 ZF-HD protein dimerisation region ACC_central PF08326.7 EJS41898.1 - 3.7e-266 884.8 0.1 4.8e-266 884.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EJS41898.1 - 3.8e-181 602.7 0.0 5.2e-181 602.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EJS41898.1 - 1.2e-50 171.7 0.0 2.4e-50 170.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EJS41898.1 - 9.1e-26 90.1 0.0 1.9e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EJS41898.1 - 3.3e-21 75.2 0.0 1.3e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EJS41898.1 - 8e-17 60.6 0.3 2e-16 59.4 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EJS41898.1 - 6.5e-11 42.2 0.0 1.7e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EJS41898.1 - 9.7e-10 37.6 0.0 3e-08 32.7 0.0 2.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EJS41898.1 - 0.00066 19.1 0.0 0.0023 17.3 0.0 1.9 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EJS41898.1 - 0.0056 16.5 0.0 0.029 14.2 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EJS41898.1 - 0.061 12.6 0.0 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain HIG_1_N PF04588.8 EJS41899.1 - 1.8e-05 24.3 1.3 2.2e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region cwf21 PF08312.7 EJS41899.1 - 0.05 13.4 1.1 0.12 12.2 0.8 1.7 1 0 0 1 1 1 0 cwf21 domain MBOAT PF03062.14 EJS41900.1 - 1.5e-92 310.2 36.8 2.4e-92 309.5 25.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EJS41900.1 - 0.00026 20.9 4.9 0.0008 19.4 3.4 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF3439 PF11921.3 EJS41900.1 - 0.33 10.6 10.2 0.067 12.9 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FtsH_ext PF06480.10 EJS41900.1 - 0.78 9.9 3.8 15 5.7 0.1 2.5 2 0 0 2 2 2 0 FtsH Extracellular DUF1682 PF07946.9 EJS41901.1 - 1.2e-83 280.5 10.3 1.4e-83 280.3 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ribosomal_L9_N PF01281.14 EJS41902.1 - 0.00088 18.4 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain WD40 PF00400.27 EJS41904.1 - 4.7e-05 23.1 0.5 0.0092 15.8 0.1 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Phos_pyr_kin PF08543.7 EJS41905.1 - 1.4e-10 40.8 0.0 1.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EJS41905.1 - 2.2e-06 27.0 0.0 1e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Pro_isomerase PF00160.16 EJS41906.1 - 1.2e-14 54.7 0.0 2.7e-14 53.6 0.0 1.4 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD cobW PF02492.14 EJS41907.1 - 1.8e-42 144.7 0.0 2.8e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EJS41907.1 - 8.9e-07 28.5 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_18 PF13238.1 EJS41907.1 - 0.0013 19.0 0.3 0.004 17.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EJS41907.1 - 0.0053 16.4 0.0 0.023 14.4 0.0 2.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EJS41907.1 - 0.0099 16.0 0.2 0.51 10.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EJS41907.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EJS41907.1 - 0.011 15.2 0.1 0.052 13.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EJS41907.1 - 0.018 15.0 0.0 0.047 13.6 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EJS41907.1 - 0.019 14.6 1.0 0.047 13.3 0.1 2.0 2 1 0 2 2 2 0 Archaeal ATPase GTP_EFTU PF00009.22 EJS41907.1 - 0.022 14.2 0.5 0.36 10.2 0.1 2.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NACHT PF05729.7 EJS41907.1 - 0.022 14.4 0.1 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EJS41907.1 - 0.025 14.4 0.1 0.22 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AF0941-like PF14591.1 EJS41907.1 - 0.032 14.3 0.1 1.7 8.7 0.0 2.9 2 1 0 2 2 2 0 AF0941-like AAA_10 PF12846.2 EJS41907.1 - 0.05 13.0 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DAP3 PF10236.4 EJS41907.1 - 0.065 12.1 0.1 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.1 EJS41907.1 - 0.084 13.6 1.3 0.54 11.0 0.9 2.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EJS41907.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Glyco_transf_22 PF03901.12 EJS41908.1 - 1.8e-34 119.5 24.9 2.2e-34 119.2 17.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.20 EJS41909.1 - 2.9e-62 210.1 0.0 1.1e-61 208.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41909.1 - 2.1e-34 118.7 0.1 7.6e-25 87.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EJS41909.1 - 2.2e-07 30.1 0.0 9.7e-05 21.4 0.0 3.3 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EJS41909.1 - 0.088 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Metallophos PF00149.23 EJS41910.1 - 1.4e-41 142.1 1.2 2.1e-41 141.5 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ubiquitin PF00240.18 EJS41911.1 - 4.2e-07 29.2 0.4 4.9e-07 29.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EJS41911.1 - 0.00067 19.2 0.2 0.00073 19.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EJS41911.1 - 0.006 16.8 0.3 0.038 14.2 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain CC2D2AN-C2 PF15625.1 EJS41911.1 - 0.01 15.3 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain Chorismate_bind PF00425.13 EJS41912.1 - 1.2e-64 218.1 0.0 1.6e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EJS41912.1 - 3.4e-32 111.4 0.0 5.5e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EJS41912.1 - 4.7e-13 49.3 0.0 1.2e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EJS41912.1 - 3.1e-05 23.5 0.0 6.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Glucosamine_iso PF01182.15 EJS41913.1 - 4.3e-47 160.4 0.0 8.4e-47 159.4 0.0 1.4 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Inhibitor_I9 PF05922.11 EJS41914.1 - 2.7e-05 24.6 0.6 3.7e-05 24.1 0.4 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 UPF0052 PF01933.13 EJS41915.1 - 1.9e-81 273.6 0.0 3.7e-81 272.7 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF3842 PF12953.2 EJS41915.1 - 0.087 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) HAD PF12710.2 EJS41916.1 - 1.2e-15 58.1 0.0 1.6e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EJS41916.1 - 1.4e-07 30.9 0.0 2.2e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 EJS41916.1 - 3.6e-05 23.2 0.0 6.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 EJS41916.1 - 0.00021 21.5 0.0 0.0027 17.9 0.0 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.7 EJS41916.1 - 0.013 15.6 0.0 0.32 11.1 0.0 2.7 2 2 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Iso_dh PF00180.15 EJS41917.1 - 9.8e-72 241.7 0.1 1.1e-71 241.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CTDII PF01556.13 EJS41918.1 - 3.4e-24 84.5 0.4 2.6e-20 72.0 0.0 2.5 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EJS41918.1 - 3.3e-23 81.1 0.7 5.4e-23 80.4 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 EJS41919.1 - 1.4e-50 167.4 15.8 8.4e-12 44.5 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EJS41919.1 - 1.2e-10 40.2 13.1 0.0049 15.0 0.3 5.0 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EJS41919.1 - 5e-07 28.8 3.0 0.081 11.6 0.3 3.9 1 1 1 2 2 2 2 Nup133 N terminal like Nbas_N PF15492.1 EJS41919.1 - 0.00077 18.6 0.7 1 8.3 0.2 2.9 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EJS41919.1 - 0.0015 16.9 0.0 0.05 11.8 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain Hira PF07569.6 EJS41919.1 - 0.0035 16.5 0.2 2 7.5 0.0 3.6 2 1 2 4 4 4 1 TUP1-like enhancer of split DUF3312 PF11768.3 EJS41919.1 - 0.0055 14.9 0.0 0.011 13.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Coatomer_WDAD PF04053.9 EJS41919.1 - 0.015 14.1 0.0 0.04 12.7 0.0 1.6 1 1 1 2 2 2 0 Coatomer WD associated region Ribosomal_L27 PF01016.14 EJS41920.1 - 1.8e-31 107.7 0.1 3.1e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Mito_carr PF00153.22 EJS41921.1 - 1.2e-52 175.5 5.6 2e-20 72.3 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4126 PF13548.1 EJS41921.1 - 0.021 14.2 0.1 0.044 13.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) Ribosomal_L30 PF00327.15 EJS41922.1 - 8.9e-14 50.8 0.6 2.4e-13 49.4 0.4 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e eRF1_2 PF03464.10 EJS41923.1 - 7.2e-33 113.7 0.2 1.4e-32 112.8 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EJS41923.1 - 2.9e-24 85.4 1.2 5.1e-24 84.7 0.1 2.0 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 EJS41923.1 - 4e-11 42.5 0.1 6.6e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 SNF2_N PF00176.18 EJS41923.1 - 0.091 11.5 0.2 0.16 10.7 0.1 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Citrate_synt PF00285.16 EJS41924.1 - 9.4e-102 340.3 0.0 1.2e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Myco_arth_vir_N PF09610.5 EJS41926.1 - 0.039 13.8 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Y_phosphatase2 PF03162.8 EJS41927.1 - 1e-67 226.6 0.3 1.6e-67 225.9 0.0 1.4 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EJS41927.1 - 1.5e-07 31.8 0.0 3.8e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EJS41927.1 - 0.0017 17.9 0.0 0.0046 16.5 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EJS41927.1 - 0.0028 17.0 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TMEM192 PF14802.1 EJS41927.1 - 0.044 12.6 0.6 2.1 7.1 0.1 2.3 2 0 0 2 2 2 0 TMEM192 family Histone PF00125.19 EJS41928.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EJS41928.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EJS41928.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EJS41928.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EJS41929.1 - 7.9e-15 54.7 0.2 9.6e-15 54.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EJS41929.1 - 7e-05 22.9 0.1 9.7e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EJS41929.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EJS41929.1 - 0.00018 21.4 0.1 0.00032 20.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EJS41929.1 - 0.0021 17.3 0.0 0.0022 17.2 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EJS41929.1 - 0.024 14.3 0.0 0.029 14.0 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EJS41929.1 - 0.06 13.6 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Glyco_transf_15 PF01793.11 EJS41930.1 - 1.2e-123 412.3 14.7 1.9e-123 411.6 10.2 1.3 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF2457 PF10446.4 EJS41930.1 - 0.32 9.6 1.0 0.43 9.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Bac_surface_Ag PF01103.18 EJS41931.1 - 5.1e-46 157.6 0.8 6.8e-46 157.2 0.5 1.2 1 0 0 1 1 1 1 Surface antigen Cyclin_N PF00134.18 EJS41932.1 - 4.3e-18 65.1 0.7 5.1e-17 61.6 0.2 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EJS41932.1 - 0.17 11.8 3.9 0.86 9.5 0.0 3.2 3 0 0 3 3 3 0 Cyclin, C-terminal domain DUF1242 PF06842.7 EJS41933.1 - 4e-18 64.6 0.2 5.4e-18 64.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Pkinase PF00069.20 EJS41934.1 - 3.9e-37 127.8 0.0 6.8e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41934.1 - 5.5e-28 97.7 0.0 8e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS41934.1 - 0.00026 20.0 0.0 0.00048 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EJS41934.1 - 0.0023 17.6 0.0 0.28 10.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family C2 PF00168.25 EJS41935.1 - 8.5e-48 160.1 3.4 2.5e-16 59.2 0.0 4.9 4 0 0 4 4 4 4 C2 domain OmpH PF03938.9 EJS41935.1 - 0.0078 16.1 0.7 0.016 15.1 0.5 1.4 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) CCDC-167 PF15188.1 EJS41935.1 - 9.6 6.2 8.8 23 5.0 6.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Snapin_Pallidin PF14712.1 EJS41936.1 - 1.1e-06 28.8 0.8 1.3e-06 28.6 0.5 1.0 1 0 0 1 1 1 1 Snapin/Pallidin FlaC_arch PF05377.6 EJS41936.1 - 0.04 13.8 0.5 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Bacillus_HBL PF05791.6 EJS41936.1 - 0.05 12.9 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF4201 PF13870.1 EJS41936.1 - 0.066 12.6 0.2 0.088 12.2 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) HR1 PF02185.11 EJS41936.1 - 0.11 12.2 2.9 2.4 7.9 0.1 2.7 3 0 0 3 3 3 0 Hr1 repeat EF-hand_4 PF12763.2 EJS41937.1 - 3.5e-52 174.4 3.8 7.6e-49 163.7 1.6 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 EJS41937.1 - 2e-25 89.6 12.0 1.2e-12 47.8 0.0 2.4 1 1 1 2 2 2 2 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.27 EJS41937.1 - 0.0012 18.0 2.4 0.049 12.9 1.1 2.6 2 0 0 2 2 2 1 EF hand Erp_C PF06780.6 EJS41937.1 - 0.01 15.7 9.0 0.01 15.7 6.2 2.4 2 0 0 2 2 2 0 Erp protein C-terminus EF-hand_8 PF13833.1 EJS41937.1 - 0.045 13.3 1.1 0.18 11.4 0.5 2.2 2 0 0 2 2 2 0 EF-hand domain pair Sugarporin_N PF11471.3 EJS41937.1 - 0.069 12.7 0.2 0.069 12.7 0.1 1.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Wbp11 PF09429.5 EJS41937.1 - 0.19 11.7 8.7 0.04 13.8 2.9 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 DUF2335 PF10097.4 EJS41937.1 - 0.22 11.1 0.0 0.22 11.1 0.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2335) CENP-Q PF13094.1 EJS41937.1 - 0.24 11.4 10.9 1.2 9.1 1.0 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CorA PF01544.13 EJS41937.1 - 0.32 9.9 8.2 6.6 5.6 5.4 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Mito_carr PF00153.22 EJS41938.1 - 3e-60 199.9 3.8 1.7e-19 69.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EJS41938.1 - 1.8e-13 50.4 2.9 4.5e-08 33.1 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EJS41938.1 - 3.7e-12 44.5 2.7 0.0075 15.4 0.1 4.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EJS41938.1 - 5.6e-12 44.4 1.5 0.015 15.1 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EJS41938.1 - 1.8e-07 30.6 4.0 0.034 13.7 0.2 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EJS41938.1 - 7.7e-06 25.0 1.0 0.014 14.6 0.1 3.7 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 EJS41938.1 - 0.0059 16.4 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EJS41938.1 - 0.019 14.9 0.6 7.1 6.6 0.0 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DNA_mis_repair PF01119.14 EJS41939.1 - 1.7e-24 85.5 0.3 4.3e-24 84.2 0.2 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EJS41939.1 - 1.7e-22 79.5 0.0 5e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EJS41939.1 - 2.9e-12 46.4 0.0 1.3e-11 44.3 0.0 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EJS41939.1 - 2.7e-11 43.1 0.0 5.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S13 PF00416.17 EJS41940.1 - 8.8e-24 84.0 0.0 1.1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EJS41940.1 - 0.0026 16.3 0.0 0.0026 16.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.3 EJS41940.1 - 0.032 14.2 0.1 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 IMS family HHH motif EOS1 PF12326.3 EJS41941.1 - 3.3e-72 240.9 1.5 6.5e-72 240.0 1.0 1.5 1 0 0 1 1 1 1 N-glycosylation protein Tropomyosin_1 PF12718.2 EJS41942.1 - 1.3e-53 180.6 61.3 4.4e-36 123.8 27.2 2.0 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 EJS41942.1 - 7.9e-12 44.7 53.1 2.9e-06 26.5 17.7 2.0 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.4 EJS41942.1 - 1.2e-06 28.4 38.1 0.024 14.6 7.8 3.1 1 1 2 3 3 3 3 Predicted coiled-coil domain-containing protein CENP-F_leu_zip PF10473.4 EJS41942.1 - 2.7e-05 24.0 58.0 3.9e-05 23.5 9.0 3.5 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 EJS41942.1 - 0.00071 19.3 65.5 0.028 14.1 6.8 4.4 1 1 3 4 4 4 2 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 EJS41942.1 - 0.0048 16.8 49.7 0.27 11.2 3.2 5.4 2 1 3 5 5 5 3 bZIP transcription factor Rootletin PF15035.1 EJS41942.1 - 0.0068 16.4 48.5 0.063 13.2 7.7 3.1 1 1 2 3 3 3 2 Ciliary rootlet component, centrosome cohesion DUF4201 PF13870.1 EJS41942.1 - 0.0081 15.6 45.6 0.26 10.6 6.4 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) IFP_35_N PF07334.8 EJS41942.1 - 0.0082 16.0 3.3 0.0082 16.0 2.3 4.6 3 2 2 5 5 4 2 Interferon-induced 35 kDa protein (IFP 35) N-terminus CENP-K PF11802.3 EJS41942.1 - 0.01 15.0 9.3 0.01 15.0 6.4 2.2 1 1 1 2 2 2 0 Centromere-associated protein K Filament PF00038.16 EJS41942.1 - 0.012 15.0 45.0 0.016 14.6 31.2 1.3 1 0 0 1 1 1 0 Intermediate filament protein ATG16 PF08614.6 EJS41942.1 - 0.013 15.3 48.8 0.25 11.1 8.7 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 EJS41942.1 - 0.021 14.3 54.0 0.065 12.7 5.4 5.2 1 1 4 5 5 5 0 Septum formation initiator DUF3287 PF11690.3 EJS41942.1 - 0.025 14.6 4.1 0.025 14.6 2.8 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) ADIP PF11559.3 EJS41942.1 - 0.045 13.6 50.9 3.2 7.6 11.2 3.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 EJS41942.1 - 0.071 10.8 52.4 0.17 9.6 23.5 2.0 1 1 1 2 2 2 0 Myosin tail Atg14 PF10186.4 EJS41942.1 - 0.077 11.9 43.1 0.019 13.8 7.3 2.8 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 WXG100 PF06013.7 EJS41942.1 - 0.11 12.5 20.8 0.39 10.7 0.5 4.4 2 1 2 4 4 4 0 Proteins of 100 residues with WXG ERM PF00769.14 EJS41942.1 - 0.13 11.7 54.0 0.46 9.9 18.4 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 EJS41942.1 - 0.16 11.5 55.1 0.83 9.2 18.1 2.8 1 1 2 3 3 3 0 IncA protein APG6 PF04111.7 EJS41942.1 - 0.18 10.7 55.4 1 8.3 18.2 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 EJS41942.1 - 0.19 8.9 43.2 0.24 8.6 29.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.7 EJS41942.1 - 0.25 11.0 33.8 0.87 9.3 7.2 3.0 1 1 2 3 3 3 0 Laminin Domain II GAS PF13851.1 EJS41942.1 - 0.51 9.4 52.8 3.5 6.7 27.5 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EJS41942.1 - 0.52 9.4 13.4 1.8 7.7 2.8 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF4200 PF13863.1 EJS41942.1 - 0.81 9.6 56.5 9.9 6.1 19.8 4.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Mod_r PF07200.8 EJS41942.1 - 0.82 9.5 45.9 7 6.5 15.7 3.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.4 EJS41942.1 - 0.86 9.7 41.9 0.74 9.9 5.9 4.1 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ax_dynein_light PF10211.4 EJS41942.1 - 0.93 9.2 51.4 1.2 8.9 10.5 3.2 1 1 0 3 3 3 0 Axonemal dynein light chain Mnd1 PF03962.10 EJS41942.1 - 1.1 8.9 49.0 1.6 8.3 14.4 2.7 1 1 2 3 3 3 0 Mnd1 family Sec2p PF06428.6 EJS41942.1 - 1.3 8.9 47.3 0.1 12.4 12.1 3.7 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p EzrA PF06160.7 EJS41942.1 - 1.3 7.1 40.8 0.14 10.3 5.5 2.4 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF3450 PF11932.3 EJS41942.1 - 1.9 7.6 41.4 0.96 8.6 7.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF724 PF05266.9 EJS41942.1 - 2 7.9 43.2 2.4 7.7 11.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) bZIP_2 PF07716.10 EJS41942.1 - 2.9 7.7 50.8 0.43 10.4 3.0 5.8 3 2 3 6 6 5 0 Basic region leucine zipper DUF3349 PF11829.3 EJS41942.1 - 3.3 8.1 8.0 0.89 10.0 1.0 2.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) DUF904 PF06005.7 EJS41942.1 - 4.1 7.7 62.1 7.2 6.9 5.3 4.6 2 1 0 2 2 1 0 Protein of unknown function (DUF904) Fib_alpha PF08702.5 EJS41942.1 - 4.2 7.4 32.2 0.97 9.5 10.9 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 EJS41942.1 - 5.5 7.3 43.1 20 5.6 11.1 3.7 1 1 1 2 2 1 0 Protein of unknown function (DUF972) Nup54 PF13874.1 EJS41942.1 - 6.2 6.4 32.0 2.5 7.7 5.8 3.0 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 DivIVA PF05103.8 EJS41942.1 - 6.3 6.8 45.5 2.1 8.3 2.2 4.0 1 1 2 3 3 3 0 DivIVA protein DUF4600 PF15372.1 EJS41942.1 - 9.2 6.4 41.2 33 4.7 14.3 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) TBPIP PF07106.8 EJS41942.1 - 9.6 5.7 49.0 2.2 7.8 12.1 3.2 1 1 2 3 3 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DnaJ PF00226.26 EJS41943.1 - 1.4e-22 79.1 1.9 2.4e-22 78.4 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EJS41943.1 - 6.4e-16 58.0 1.9 4.7e-15 55.2 0.1 2.6 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EJS41943.1 - 2.5e-10 40.2 15.5 6.8e-10 38.8 10.7 1.8 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EJS41943.1 - 0.085 12.5 4.7 1.2 8.7 0.3 2.7 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF1217 PF06748.7 EJS41943.1 - 0.1 12.6 1.5 0.23 11.5 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) DUF1752 PF08550.5 EJS41944.1 - 5.1e-11 41.9 0.1 1.7e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Brix PF04427.13 EJS41945.1 - 1.1e-46 158.9 0.2 1.4e-46 158.6 0.1 1.1 1 0 0 1 1 1 1 Brix domain Bromodomain PF00439.20 EJS41945.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Bromodomain tRNA-synt_2 PF00152.15 EJS41946.1 - 3.2e-68 229.9 0.2 4.3e-68 229.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EJS41946.1 - 9.9e-08 31.4 0.4 4.2e-05 22.8 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EJS41946.1 - 1.7e-07 31.0 0.0 3.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ribosomal_L37 PF08561.5 EJS41946.1 - 0.045 13.3 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 RNase_HII PF01351.13 EJS41947.1 - 3.1e-68 229.3 0.0 4.6e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Adeno_GP19K PF04881.8 EJS41947.1 - 0.04 13.6 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Adenovirus GP19K 2-oxoacid_dh PF00198.18 EJS41948.1 - 7.7e-73 244.5 1.0 1e-72 244.1 0.7 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EJS41948.1 - 2.8e-17 62.1 0.1 5.6e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EJS41948.1 - 1.3e-16 59.9 0.6 3.9e-16 58.4 0.4 1.9 1 0 0 1 1 1 1 e3 binding domain DEC-1_N PF04625.8 EJS41948.1 - 0.014 14.1 0.9 0.023 13.4 0.6 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region L1R_F9L PF02442.12 EJS41948.1 - 0.035 13.5 2.3 0.038 13.4 0.2 2.0 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses Tom7 PF08038.7 EJS41949.1 - 6e-20 70.4 0.1 7.7e-20 70.0 0.1 1.1 1 0 0 1 1 1 1 TOM7 family NUMOD3 PF07460.6 EJS41949.1 - 0.054 13.4 0.0 0.074 12.9 0.0 1.1 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) Fork_head PF00250.13 EJS41950.1 - 5.3e-38 128.9 0.8 1.5e-37 127.5 0.5 1.7 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EJS41950.1 - 9.5e-12 44.8 0.1 2.9e-11 43.3 0.1 1.9 1 1 0 1 1 1 1 FHA domain Ribosomal_L6 PF00347.18 EJS41951.1 - 4.2e-29 100.8 10.5 2.9e-15 56.5 2.9 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 LRR_4 PF12799.2 EJS41951.1 - 0.079 12.6 0.1 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) UAF_Rrn10 PF05234.6 EJS41951.1 - 0.16 12.0 1.2 0.21 11.6 0.2 1.7 2 0 0 2 2 2 0 UAF complex subunit Rrn10 SUN PF03856.8 EJS41952.1 - 2.5e-106 354.5 14.3 3.8e-106 353.9 9.9 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Macoilin PF09726.4 EJS41952.1 - 2.4 6.3 14.4 3.2 5.9 10.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DnaJ PF00226.26 EJS41953.1 - 1e-26 92.4 1.2 1.7e-26 91.6 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EJS41953.1 - 5.1e-20 71.1 0.8 5e-17 61.5 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EJS41953.1 - 3e-14 52.8 17.9 5.1e-14 52.0 12.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EJS41953.1 - 0.028 14.1 10.8 0.35 10.5 1.4 2.4 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EJS41953.1 - 5.6 7.3 10.2 7.1 7.0 1.6 2.5 1 1 2 3 3 3 0 Cytochrome c3 Cytochrome_C7 PF14522.1 EJS41953.1 - 7.2 6.3 8.6 32 4.2 5.9 2.2 1 1 0 1 1 1 0 Cytochrome c7 Gcd10p PF04189.8 EJS41954.1 - 7.6e-104 347.0 6.7 9.3e-104 346.7 4.6 1.1 1 0 0 1 1 1 1 Gcd10p family Mrr_N PF14338.1 EJS41954.1 - 0.12 12.4 1.1 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Mrr N-terminal domain Nol1_Nop2_Fmu PF01189.12 EJS41955.1 - 2.9e-110 368.1 0.0 4.6e-110 367.4 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EJS41955.1 - 0.0026 17.7 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EJS41955.1 - 0.0064 16.0 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Actin PF00022.14 EJS41956.1 - 1.5e-55 188.2 0.0 3.5e-32 111.3 0.0 2.5 2 2 0 2 2 2 2 Actin SoxE PF06525.6 EJS41957.1 - 3.1 7.0 9.5 3.9 6.6 6.1 1.5 1 1 0 1 1 1 0 Sulfocyanin (SoxE) Porin_3 PF01459.17 EJS41958.1 - 4.4e-59 200.0 0.9 4.9e-59 199.8 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin Vac7 PF12751.2 EJS41959.1 - 4.8e-17 61.8 18.6 5.3e-12 45.2 4.5 4.8 3 2 1 4 4 4 2 Vacuolar segregation subunit 7 DUF3493 PF11998.3 EJS41959.1 - 0.21 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) DSPc PF00782.15 EJS41960.1 - 1e-36 125.4 0.0 2e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EJS41960.1 - 1.4e-05 24.5 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EJS41960.1 - 0.033 13.0 0.1 0.033 13.0 0.1 2.1 1 1 1 2 2 2 0 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 EJS41960.1 - 0.12 12.3 1.8 0.16 12.0 0.0 2.1 2 1 1 3 3 3 0 Inositol hexakisphosphate COX4 PF02936.9 EJS41961.1 - 6e-45 152.4 0.4 6.7e-45 152.3 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1289 PF06945.8 EJS41961.1 - 0.0053 16.2 1.4 0.66 9.4 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1289) N1221 PF07923.8 EJS41961.1 - 0.034 13.0 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 N1221-like protein Sec23_trunk PF04811.10 EJS41962.1 - 2.4e-66 223.5 0.1 1e-65 221.5 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EJS41962.1 - 2.4e-22 78.2 1.8 4.4e-22 77.4 0.4 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EJS41962.1 - 2.7e-17 62.0 6.6 5e-17 61.1 4.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EJS41962.1 - 9e-16 58.1 0.4 2.3e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EJS41962.1 - 4.7e-07 29.3 0.0 1.1e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat RXT2_N PF08595.6 EJS41962.1 - 0.091 12.5 7.3 0.21 11.3 5.0 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal RRN3 PF05327.6 EJS41962.1 - 0.58 8.1 7.2 1.1 7.3 5.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.8 EJS41962.1 - 1.2 8.6 16.1 2.6 7.6 11.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 EJS41962.1 - 5.3 4.9 13.8 8.1 4.3 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 EJS41962.1 - 6.4 6.4 6.5 19 4.9 4.5 1.7 1 0 0 1 1 1 0 FAM176 family Pox_RNA_Pol_19 PF05320.7 EJS41962.1 - 8.1 6.1 10.8 16 5.1 6.2 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Glycos_transf_1 PF00534.15 EJS41963.1 - 2.6e-19 69.2 0.0 4.5e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EJS41963.1 - 0.0022 17.7 0.0 0.0075 15.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EJS41963.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Peptidase_M1 PF01433.15 EJS41965.1 - 3.9e-87 292.8 0.0 5.3e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EJS41965.1 - 3.8e-48 162.7 0.8 6.8e-48 161.9 0.6 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EJS41965.1 - 5.3e-15 55.5 0.0 8.5e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EJS41965.1 - 0.17 11.9 2.2 1.3 8.9 1.5 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF2722 PF10846.3 EJS41966.1 - 3.4e-88 296.4 27.4 3.7e-88 296.3 19.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) COG6 PF06419.6 EJS41967.1 - 5.2e-168 560.0 21.4 5.2e-168 560.0 14.8 1.9 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 zf-AD PF07776.10 EJS41967.1 - 0.029 14.3 0.1 0.4 10.7 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) DUF970 PF06153.6 EJS41967.1 - 0.063 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF970) Pro_CA PF00484.14 EJS41968.1 - 1.6e-36 125.6 0.3 2.1e-36 125.2 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DUF4294 PF14127.1 EJS41968.1 - 0.036 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) Iso_dh PF00180.15 EJS41969.1 - 3.2e-75 253.2 0.2 3.6e-75 253.0 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase tRNA_SAD PF07973.9 EJS41970.1 - 1.5e-09 37.6 0.2 4e-09 36.2 0.2 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EJS41970.1 - 0.00022 19.6 0.1 0.00059 18.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (A) Mem_trans PF03547.13 EJS41971.1 - 1.9e-89 299.6 0.0 1.1e-88 297.1 0.0 1.9 1 1 0 1 1 1 1 Membrane transport protein DUF2183 PF09949.4 EJS41972.1 - 4.5e-32 109.9 0.1 1.9e-31 107.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Ras PF00071.17 EJS41973.1 - 1.2e-55 187.3 0.1 1.5e-55 187.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS41973.1 - 6.2e-20 71.8 0.0 1.1e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS41973.1 - 4e-18 65.2 0.0 5e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EJS41973.1 - 3.5e-08 32.8 0.0 4.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EJS41973.1 - 1.8e-07 30.8 0.1 4.2e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EJS41973.1 - 7.9e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EJS41973.1 - 0.032 13.4 0.0 0.087 12.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NST1 PF13945.1 EJS41974.1 - 4.8e-13 49.5 7.2 4.8e-13 49.5 5.0 5.3 2 2 2 4 4 4 1 Salt tolerance down-regulator Ras PF00071.17 EJS41975.1 - 3.1e-50 169.7 0.0 3.6e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS41975.1 - 2.2e-13 50.7 0.0 3.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS41975.1 - 6e-09 35.3 0.0 9.4e-09 34.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 EJS41975.1 - 0.0002 20.8 0.0 0.29 10.6 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EJS41975.1 - 0.037 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.1 EJS41975.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DNA_topoisoIV PF00521.15 EJS41976.1 - 8e-123 410.4 0.2 8e-123 410.4 0.2 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EJS41976.1 - 1e-32 112.7 4.3 2.5e-32 111.4 2.9 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EJS41976.1 - 2e-12 46.9 0.1 1.3e-11 44.2 0.0 2.5 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EJS41976.1 - 7.6e-11 41.7 0.0 2.4e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Arm PF00514.18 EJS41977.1 - 8.4e-88 285.5 13.1 1.6e-12 46.7 0.2 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 EJS41977.1 - 1.3e-27 95.7 6.1 2.6e-27 94.8 4.3 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 EJS41977.1 - 2.5e-21 75.7 0.5 3.1e-05 24.1 0.0 5.7 1 1 5 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 EJS41977.1 - 7.6e-17 61.2 3.1 0.00018 21.9 0.0 6.4 4 2 4 8 8 8 4 HEAT-like repeat HEAT PF02985.17 EJS41977.1 - 3.5e-12 45.3 0.2 2.5 8.4 0.0 7.8 8 0 0 8 8 8 2 HEAT repeat Arm_2 PF04826.8 EJS41977.1 - 1e-07 31.3 0.3 0.015 14.4 0.0 4.0 3 2 1 4 4 4 2 Armadillo-like Proteasom_PSMB PF10508.4 EJS41977.1 - 3.8e-06 25.4 2.3 0.00016 20.0 0.1 2.7 3 0 0 3 3 3 2 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 EJS41977.1 - 6.3e-06 24.7 0.9 0.002 16.5 0.0 3.5 1 1 2 3 3 3 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 EJS41977.1 - 1.5e-05 24.8 0.3 0.099 12.5 0.0 4.3 3 2 1 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.1 EJS41977.1 - 0.00067 19.5 4.3 8 6.4 0.0 5.3 3 3 4 7 7 7 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 EJS41977.1 - 0.016 15.6 0.8 46 4.8 0.1 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF2505 PF10698.4 EJS41977.1 - 0.086 12.3 0.3 3.8 7.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2505) FAST_1 PF06743.10 EJS41977.1 - 0.14 11.8 0.1 1.2 8.9 0.0 2.6 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 Lactonase PF10282.4 EJS41979.1 - 0.12 11.3 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller UCH PF00443.24 EJS41980.1 - 4.9e-58 196.3 3.1 4.9e-58 196.3 2.1 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EJS41980.1 - 3.4e-14 52.9 6.4 4.3e-13 49.3 4.4 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.8 EJS41980.1 - 0.07 12.6 1.9 2.2 7.7 0.1 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_L11 PF00298.14 EJS41981.1 - 6.2e-28 96.7 0.5 1.2e-27 95.7 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EJS41981.1 - 1.1e-25 88.8 0.6 1.8e-25 88.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain WD40 PF00400.27 EJS41982.1 - 1.5e-08 34.2 4.2 0.026 14.4 0.2 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat CBM_19 PF03427.8 EJS41982.1 - 0.0034 17.1 2.7 0.045 13.5 0.3 2.6 2 0 0 2 2 2 1 Carbohydrate binding domain (family 19) MRP-L28 PF09812.4 EJS41982.1 - 0.011 15.5 0.8 0.019 14.7 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 Ras PF00071.17 EJS41983.1 - 4.2e-44 149.7 0.0 1.3e-29 102.6 0.0 2.4 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EJS41983.1 - 5e-15 56.0 0.7 1e-13 51.8 0.0 3.2 2 2 0 2 2 2 1 Miro-like protein Arf PF00025.16 EJS41983.1 - 3e-06 26.6 0.0 0.015 14.5 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_16 PF13191.1 EJS41983.1 - 0.2 11.6 0.7 16 5.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_S3_C PF00189.15 EJS41984.1 - 1.4e-15 57.2 0.1 2.5e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EJS41984.1 - 6.4e-12 44.8 0.0 2.3e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 KH domain Syndecan PF01034.15 EJS41985.1 - 0.028 14.0 0.1 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 EJS41985.1 - 0.12 11.7 0.3 0.33 10.3 0.2 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RRM_1 PF00076.17 EJS41986.1 - 7.6e-27 92.7 0.9 1.7e-17 62.8 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS41986.1 - 7.9e-20 70.6 0.7 2.3e-12 46.7 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS41986.1 - 4.4e-10 39.2 1.4 1.5e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AF1Q PF15017.1 EJS41987.1 - 0.62 9.9 9.3 0.24 11.2 4.3 2.0 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator BMF PF15185.1 EJS41987.1 - 2.1 7.5 8.1 4.4 6.5 5.2 1.7 2 0 0 2 2 2 0 Bcl-2-modifying factor, apoptosis PS_Dcarbxylase PF02666.10 EJS41988.1 - 9.8e-74 247.0 0.0 1.4e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.17 EJS41988.1 - 0.012 15.6 0.0 0.7 9.9 0.0 2.8 2 0 0 2 2 2 0 Peptidase family M23 FAA_hydrolase PF01557.13 EJS41989.1 - 1.4e-47 161.9 0.0 1.9e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family bZIP_1 PF00170.16 EJS41990.1 - 1.3e-06 28.2 4.0 1.3e-06 28.2 2.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor Aft1_OSA PF11785.3 EJS41990.1 - 6.4e-06 26.6 1.4 6.4e-06 26.6 0.9 4.0 3 2 2 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EJS41990.1 - 3.5e-05 23.5 5.3 3.5e-05 23.5 3.7 2.3 3 0 0 3 3 3 1 Basic region leucine zipper HtaA PF04213.8 EJS41993.1 - 0.09 13.0 0.1 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Htaa GTP_EFTU PF00009.22 EJS41994.1 - 2e-53 180.6 0.0 3.2e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EJS41994.1 - 1.7e-13 50.2 0.0 4.3e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EJS41994.1 - 5.6e-10 39.1 0.0 1.4e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EJS41994.1 - 1.4e-09 37.6 0.0 3.5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EJS41994.1 - 0.00011 21.7 0.0 0.00049 19.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EJS41994.1 - 0.0014 18.6 0.0 0.0082 16.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Pkinase PF00069.20 EJS41995.1 - 1.1e-57 195.2 9.5 1.6e-39 135.5 0.1 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EJS41995.1 - 4.5e-24 84.9 0.4 2.1e-20 72.8 0.0 3.0 3 0 0 3 3 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EJS41995.1 - 0.0013 19.2 0.1 0.0055 17.1 0.1 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 EJS41995.1 - 0.044 12.6 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EJS41995.1 - 0.065 12.0 0.1 0.12 11.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mem_trans PF03547.13 EJS41995.1 - 0.12 10.6 0.6 0.18 10.0 0.4 1.3 1 0 0 1 1 1 0 Membrane transport protein APH PF01636.18 EJS41995.1 - 1.5 8.4 10.6 0.84 9.3 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family LMBR1 PF04791.11 EJS41995.1 - 4.4 5.7 5.2 6.5 5.2 3.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SprA-related PF12118.3 EJS41995.1 - 7.3 5.8 55.0 0.062 12.6 30.9 2.4 2 0 0 2 2 2 0 SprA-related family RR_TM4-6 PF06459.7 EJS41995.1 - 7.5 6.3 20.4 2.6 7.8 11.7 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EIIBC-GUT_N PF03612.9 EJS41995.1 - 7.9 6.0 9.2 31 4.1 6.4 2.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Asparaginase PF00710.15 EJS41996.1 - 1.4e-22 79.9 4.4 2.3e-22 79.2 3.0 1.3 1 0 0 1 1 1 1 Asparaginase Inp1 PF12634.2 EJS41996.1 - 0.063 12.9 0.8 0.16 11.6 0.6 1.6 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 TPPK_C PF12555.3 EJS41996.1 - 0.29 10.9 1.6 0.49 10.1 0.3 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Endosulfine PF04667.12 EJS41998.1 - 3.2e-32 110.3 0.2 4.4e-32 109.8 0.2 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region INSIG PF07281.7 EJS41999.1 - 2.4e-13 49.8 2.3 5.7e-13 48.6 1.6 1.7 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) zf-AN1 PF01428.11 EJS42000.1 - 9.4e-13 47.8 10.1 1.6e-12 47.0 7.0 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger RE_NgoBV PF09564.5 EJS42000.1 - 0.0015 17.8 1.3 0.0021 17.3 0.9 1.2 1 0 0 1 1 1 1 NgoBV restriction endonuclease Ipi1_N PF12333.3 EJS42000.1 - 1.9 8.5 4.3 1 9.4 0.7 2.1 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation zf-DHHC PF01529.15 EJS42000.1 - 5.6 6.3 10.3 0.93 8.8 4.2 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase Pkinase PF00069.20 EJS42001.1 - 4.2e-32 111.3 0.0 4.2e-32 111.3 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42001.1 - 2.4e-12 46.5 0.1 6.4e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Prefoldin_2 PF01920.15 EJS42002.1 - 4.2e-21 74.7 7.8 4.9e-21 74.4 5.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit NUC194 PF08163.7 EJS42002.1 - 0.0055 15.6 0.4 0.0061 15.4 0.3 1.1 1 0 0 1 1 1 1 NUC194 domain CCDC155 PF14662.1 EJS42002.1 - 0.023 14.3 3.4 1.7 8.1 0.4 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 SMK-1 PF04802.10 EJS42002.1 - 0.042 13.3 3.2 0.049 13.1 2.3 1.1 1 0 0 1 1 1 0 Component of IIS longevity pathway SMK-1 DUF4140 PF13600.1 EJS42002.1 - 0.055 13.9 1.0 0.11 12.9 0.5 1.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Nop16 PF09420.5 EJS42002.1 - 0.093 12.8 0.1 0.14 12.2 0.1 1.3 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 DUF4164 PF13747.1 EJS42002.1 - 0.21 11.7 4.1 10 6.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Seryl_tRNA_N PF02403.17 EJS42002.1 - 4.8 7.2 9.0 6.5 6.8 0.5 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PGA2 PF07543.7 EJS42003.1 - 1.2e-12 47.7 10.2 1.5e-06 28.0 0.9 2.0 1 1 1 2 2 2 2 Protein trafficking PGA2 DUF1510 PF07423.6 EJS42003.1 - 0.0082 15.5 1.0 0.0096 15.3 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF2852 PF11014.3 EJS42003.1 - 0.019 14.9 0.2 0.023 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) MscS_TM PF12794.2 EJS42003.1 - 0.2 10.2 0.6 0.26 9.8 0.0 1.4 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 ATP-synt_E PF05680.7 EJS42003.1 - 0.3 11.0 4.6 4.6 7.2 0.4 2.3 2 0 0 2 2 2 0 ATP synthase E chain DivIC PF04977.10 EJS42003.1 - 0.3 10.5 2.8 4.7 6.7 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator UPF0542 PF15086.1 EJS42003.1 - 3.6 7.3 6.9 0.31 10.7 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 CAP_GLY PF01302.20 EJS42004.1 - 2.4e-19 68.7 0.1 4.5e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EJS42004.1 - 2e-07 31.1 0.0 3.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Tub_2 PF04525.7 EJS42006.1 - 0.016 14.5 0.0 0.016 14.5 0.0 1.0 1 0 0 1 1 1 0 Tubby C 2 Ammonium_transp PF00909.16 EJS42007.1 - 1.8e-130 434.9 29.2 2.1e-130 434.7 20.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.3 EJS42007.1 - 0.075 12.8 8.5 5.4 6.8 0.4 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) A_deaminase PF00962.17 EJS42008.1 - 6.1e-95 317.9 0.0 6.8e-95 317.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF3889 PF13028.1 EJS42008.1 - 0.061 12.9 1.6 0.2 11.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) Tho2 PF11262.3 EJS42009.1 - 3e-60 203.8 11.8 3e-60 203.8 8.1 3.4 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EJS42009.1 - 3.1e-28 97.3 0.5 8.5e-28 95.9 0.3 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit CAP_N PF01213.14 EJS42010.1 - 5.9e-122 406.8 0.4 7.5e-122 406.4 0.3 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EJS42010.1 - 7.8e-63 210.5 1.8 1.2e-62 209.9 0.7 1.7 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal S4 PF01479.20 EJS42011.1 - 1.7e-17 62.5 0.0 3.9e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 S4 domain DUF3826 PF12875.2 EJS42011.1 - 0.014 15.0 1.7 0.027 14.1 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) S4_2 PF13275.1 EJS42011.1 - 0.034 13.7 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 S4 domain Eaf7 PF07904.8 EJS42012.1 - 3.5e-33 113.4 0.3 3.5e-33 113.4 0.2 4.1 3 1 0 3 3 3 1 Chromatin modification-related protein EAF7 FKBP_C PF00254.23 EJS42013.1 - 3.2e-33 113.6 0.0 3.7e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GNAT_acetyltr_2 PF13718.1 EJS42014.1 - 1.4e-81 272.4 0.0 3.3e-81 271.2 0.0 1.7 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EJS42014.1 - 1e-66 223.9 0.1 4.8e-66 221.7 0.0 2.2 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.6 EJS42014.1 - 3.4e-40 135.6 0.1 1.4e-39 133.6 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EJS42014.1 - 1.2e-36 124.8 1.2 4e-36 123.1 0.9 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EJS42014.1 - 0.11 12.7 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tom22 PF04281.8 EJS42015.1 - 5.9e-50 168.3 2.6 6.8e-50 168.1 1.8 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 AAA_18 PF13238.1 EJS42016.1 - 3.4e-10 40.3 0.7 2.8e-09 37.3 0.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EJS42016.1 - 5.2e-07 30.5 0.7 1.1e-05 26.2 0.5 2.3 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EJS42016.1 - 2.6e-06 27.1 0.1 4.5e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 EJS42016.1 - 0.004 16.7 0.0 0.05 13.2 0.0 2.4 2 1 1 3 3 3 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EJS42016.1 - 0.009 15.8 0.2 0.032 14.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EJS42016.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EJS42016.1 - 0.075 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 EJS42016.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF927 PF06048.6 EJS42016.1 - 0.13 11.4 0.0 0.54 9.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF927) DUF1374 PF07118.6 EJS42016.1 - 0.37 10.9 3.3 0.44 10.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) CbiA PF01656.18 EJS42016.1 - 3.4 7.0 4.8 42 3.4 3.3 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Spc97_Spc98 PF04130.8 EJS42017.1 - 1.7e-72 244.4 22.3 1.7e-72 244.4 15.4 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family MFS_1 PF07690.11 EJS42018.1 - 3.6e-29 101.5 53.9 2.3e-22 79.2 28.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PDZ_1 PF12812.2 EJS42019.1 - 1.3e-50 169.1 1.0 3.9e-34 116.3 0.0 3.8 4 0 0 4 4 4 2 PDZ-like domain Trypsin_2 PF13365.1 EJS42019.1 - 3.8e-13 49.4 0.1 1e-10 41.6 0.0 2.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EJS42019.1 - 1.5e-12 47.5 0.3 1.6e-08 34.6 0.0 3.0 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EJS42019.1 - 3.9e-12 45.8 2.0 0.00012 21.9 0.1 3.7 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.1 EJS42019.1 - 2.1e-05 24.2 0.4 0.052 13.3 0.1 3.0 3 0 0 3 3 3 2 Tricorn protease PDZ domain Trypsin PF00089.21 EJS42019.1 - 0.00099 18.7 0.0 0.0025 17.4 0.0 1.6 1 1 0 1 1 1 1 Trypsin DUF31 PF01732.11 EJS42019.1 - 0.015 14.6 0.2 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 EJS42019.1 - 0.039 13.3 0.2 0.11 11.9 0.1 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease 7TMR-DISMED2 PF07696.6 EJS42019.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 TPR_11 PF13414.1 EJS42020.1 - 1.5e-41 139.8 15.4 5.5e-16 57.9 0.2 6.8 3 2 1 6 6 6 6 TPR repeat TPR_16 PF13432.1 EJS42020.1 - 8.5e-30 102.7 2.4 1.1e-06 29.1 0.0 6.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EJS42020.1 - 1.5e-28 96.4 20.4 6.6e-05 22.5 0.0 11.5 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.23 EJS42020.1 - 7.9e-28 94.8 26.6 8.5e-07 28.3 1.7 11.0 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.1 EJS42020.1 - 3.5e-18 64.4 1.3 0.33 11.6 0.0 9.6 5 3 5 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EJS42020.1 - 1.2e-17 63.6 15.9 2.4e-05 24.1 0.1 8.5 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EJS42020.1 - 9.8e-17 59.7 11.3 0.00037 20.4 0.1 8.9 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EJS42020.1 - 8.1e-16 58.1 12.7 0.00026 21.2 0.7 7.5 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EJS42020.1 - 3.6e-13 48.2 28.5 0.016 14.9 0.8 9.9 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 EJS42020.1 - 1.1e-09 37.3 7.4 0.28 11.0 0.1 6.8 8 0 0 8 8 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EJS42020.1 - 1.1e-08 35.0 8.4 0.0092 16.1 0.0 4.7 2 1 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EJS42020.1 - 1e-05 25.2 0.3 4.6 7.1 0.0 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat DUF4230 PF14014.1 EJS42020.1 - 0.0078 16.0 1.6 0.022 14.6 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4230) PPR PF01535.15 EJS42020.1 - 0.042 13.8 4.6 87 3.4 0.0 6.1 7 0 0 7 7 5 0 PPR repeat DUF3808 PF10300.4 EJS42020.1 - 0.046 12.2 7.3 0.24 9.8 0.2 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF3808) SPO22 PF08631.5 EJS42020.1 - 0.062 12.3 3.7 0.72 8.8 0.4 3.4 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like SHNi-TPR PF10516.4 EJS42020.1 - 0.092 11.9 3.2 11 5.3 0.0 4.4 3 0 0 3 3 3 0 SHNi-TPR U1snRNP70_N PF12220.3 EJS42020.1 - 0.098 12.9 3.2 7.7 6.9 0.7 3.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HemY_N PF07219.8 EJS42020.1 - 0.15 11.6 0.5 8.8 5.9 0.7 2.8 2 0 0 2 2 2 0 HemY protein N-terminus TPR_6 PF13174.1 EJS42020.1 - 0.36 11.3 17.5 57 4.4 0.0 8.0 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF2225 PF09986.4 EJS42020.1 - 0.56 9.6 7.7 1 8.8 0.2 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF2392 PF10288.4 EJS42021.1 - 9e-30 103.1 2.1 1.2e-29 102.7 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) DUF3510 PF12022.3 EJS42021.1 - 0.00092 19.3 0.6 0.0026 17.8 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) GFA PF04828.9 EJS42021.1 - 0.076 12.9 1.4 8.1 6.4 0.0 3.3 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Cytochrom_c3_2 PF14537.1 EJS42021.1 - 0.32 11.3 1.8 0.49 10.7 0.1 2.2 3 0 0 3 3 3 0 Cytochrome c3 DCP2 PF05026.8 EJS42022.1 - 3e-33 113.5 1.2 7.3e-33 112.3 0.8 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EJS42022.1 - 6.6e-14 51.6 0.0 1.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SUZ PF12752.2 EJS42022.1 - 0.0027 18.2 0.0 1.9 9.0 0.0 4.1 2 1 0 2 2 2 1 SUZ domain Malate_synthase PF01274.17 EJS42023.1 - 1.6e-225 749.1 0.0 1.8e-225 748.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase FHA PF00498.21 EJS42024.1 - 1.8e-15 56.8 0.1 4.9e-15 55.4 0.1 1.8 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EJS42024.1 - 7.1e-05 22.5 12.7 0.00012 21.8 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EJS42024.1 - 0.00092 19.2 5.2 0.0018 18.3 3.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EJS42024.1 - 0.033 13.9 10.7 0.054 13.2 7.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EJS42024.1 - 0.036 13.7 12.5 0.063 12.9 8.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EJS42024.1 - 0.051 13.4 4.6 0.11 12.4 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sec_GG PF07549.9 EJS42024.1 - 0.067 12.4 0.6 0.15 11.3 0.4 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-C3HC4_2 PF13923.1 EJS42024.1 - 1.9 8.5 14.8 3.3 7.8 10.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2417 PF10329.4 EJS42025.1 - 7.5e-78 261.1 4.8 1e-77 260.6 3.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.15 EJS42025.1 - 3.5e-24 85.6 0.0 5.2e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EJS42025.1 - 8.3e-11 42.1 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family RNA_pol_L_2 PF13656.1 EJS42026.1 - 2.4e-31 106.9 0.0 4e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EJS42026.1 - 5.3e-13 47.8 0.0 1e-12 46.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RabGAP-TBC PF00566.13 EJS42026.1 - 0.1 12.0 0.2 0.17 11.3 0.1 1.3 1 1 0 1 1 1 0 Rab-GTPase-TBC domain Cyt-b5 PF00173.23 EJS42027.1 - 1e-23 82.9 0.3 1.2e-23 82.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PsaX PF08078.7 EJS42027.1 - 0.36 10.7 2.3 0.58 10.1 1.6 1.3 1 0 0 1 1 1 0 PsaX family RRM_1 PF00076.17 EJS42028.1 - 7.7e-18 63.8 0.0 1.8e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS42028.1 - 2.6e-12 46.5 0.0 5.3e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS42028.1 - 3e-09 36.5 0.0 6.1e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 EJS42028.1 - 0.0066 15.0 7.9 0.0077 14.7 5.5 1.1 1 0 0 1 1 1 1 Daxx Family Limkain-b1 PF11608.3 EJS42028.1 - 0.04 13.6 0.2 0.23 11.2 0.0 2.4 2 1 0 2 2 2 0 Limkain b1 CDC45 PF02724.9 EJS42028.1 - 0.15 10.1 8.6 0.14 10.1 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2129 PF09902.4 EJS42028.1 - 0.36 10.6 2.9 1.9 8.3 0.1 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2129) His_Phos_1 PF00300.17 EJS42029.1 - 1.7e-22 80.1 0.0 2.4e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) YEATS PF03366.11 EJS42030.1 - 1.4e-34 117.6 0.4 2.4e-34 116.8 0.3 1.4 1 0 0 1 1 1 1 YEATS family Osmo_CC PF08946.5 EJS42030.1 - 0.019 14.9 7.1 0.019 14.9 4.9 1.8 2 0 0 2 2 2 0 Osmosensory transporter coiled coil FlaC_arch PF05377.6 EJS42030.1 - 0.36 10.7 3.3 0.95 9.4 2.3 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Syja_N PF02383.13 EJS42031.1 - 2e-94 315.9 0.8 3.1e-94 315.3 0.6 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EJS42031.1 - 4.1e-26 92.4 0.3 7.3e-26 91.6 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family bZIP_2 PF07716.10 EJS42032.1 - 0.0011 18.7 3.0 0.0011 18.7 2.1 2.4 2 0 0 2 2 2 1 Basic region leucine zipper PspB PF06667.7 EJS42032.1 - 0.051 13.5 2.1 0.14 12.1 1.5 1.7 1 0 0 1 1 1 0 Phage shock protein B V_ATPase_I PF01496.14 EJS42032.1 - 2 6.1 7.7 3.4 5.4 5.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_pol_B PF00136.16 EJS42033.1 - 1.8e-117 393.0 4.0 3.1e-117 392.2 2.7 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EJS42033.1 - 4.1e-66 221.9 6.1 8.3e-66 220.9 4.2 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EJS42033.1 - 4e-57 193.5 0.0 7.3e-57 192.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EJS42033.1 - 3.8e-20 71.4 13.0 1.2e-19 69.8 9.0 2.0 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Aa_trans PF01490.13 EJS42034.1 - 9.3e-107 357.0 37.1 1.1e-106 356.7 25.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ApoO PF09769.4 EJS42035.1 - 2.6e-06 27.2 0.7 0.23 11.1 0.0 3.1 3 0 0 3 3 3 3 Apolipoprotein O Y_phosphatase2 PF03162.8 EJS42036.1 - 8.1e-60 200.9 0.0 1.7e-59 199.8 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EJS42036.1 - 1e-05 25.8 0.0 5.3e-05 23.5 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EJS42036.1 - 0.04 13.4 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Rick_17kDa_Anti PF05433.10 EJS42037.1 - 1.9e-08 33.8 2.1 1.9e-08 33.8 1.5 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EJS42037.1 - 0.00041 19.9 3.6 0.00085 18.9 2.5 1.6 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain RIO1 PF01163.17 EJS42038.1 - 3.3e-42 143.9 0.2 5.1e-42 143.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EJS42038.1 - 1.3e-31 108.5 0.1 2.5e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EJS42038.1 - 5.4e-06 26.3 0.1 0.074 12.7 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EJS42038.1 - 0.0019 17.3 0.0 0.14 11.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EJS42038.1 - 0.11 11.6 0.4 0.21 10.6 0.3 1.5 1 1 0 1 1 1 0 Protein kinase domain ArfGap PF01412.13 EJS42039.1 - 3.8e-23 81.4 1.0 7.2e-23 80.5 0.7 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SMK-1 PF04802.10 EJS42040.1 - 2.2e-65 219.8 6.7 3.7e-65 219.1 3.6 2.3 2 1 0 2 2 2 1 Component of IIS longevity pathway SMK-1 HEAT PF02985.17 EJS42040.1 - 0.068 13.2 0.0 5.2 7.4 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat YjeF_N PF03853.10 EJS42041.1 - 1.2e-35 122.6 0.0 1.4e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus RRM_1 PF00076.17 EJS42043.1 - 6.1e-18 64.2 0.0 4.5e-16 58.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS42043.1 - 2.2e-07 30.7 0.0 2.9e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EJS42043.1 - 5.4 6.6 19.5 0.048 13.3 4.1 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SUR7 PF06687.7 EJS42045.1 - 1.9e-36 125.6 14.9 2.5e-36 125.2 10.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EJS42045.1 - 0.56 10.0 8.4 1.3 8.9 5.8 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Claudin_2 PF13903.1 EJS42045.1 - 2.2 7.9 12.2 0.39 10.3 5.4 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Hormone_3 PF00159.13 EJS42046.1 - 0.91 9.5 3.1 6.4 6.8 0.0 3.1 3 0 0 3 3 3 0 Pancreatic hormone peptide Chitin_synth_1 PF01644.12 EJS42047.1 - 3e-75 251.4 0.2 4.7e-75 250.8 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EJS42047.1 - 2.9e-26 90.9 0.4 5.8e-26 89.9 0.3 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EJS42047.1 - 2.1e-16 59.4 11.3 9e-13 47.4 2.5 2.6 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EJS42047.1 - 4.5e-12 46.0 0.8 4.5e-12 46.0 0.5 1.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EJS42047.1 - 3.1e-09 36.9 0.0 1.1e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EJS42047.1 - 0.0077 15.9 0.0 0.34 10.5 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pro_3_hydrox_C PF05373.6 EJS42047.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal DUF3989 PF13150.1 EJS42047.1 - 0.33 10.4 3.2 16 5.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) GATase_4 PF13230.1 EJS42048.1 - 2.2e-18 65.9 0.0 1.4e-17 63.3 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EJS42048.1 - 1.7e-10 40.9 0.0 4.1e-10 39.7 0.0 1.7 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EJS42048.1 - 7.1e-10 38.1 0.0 3.7e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 EJS42048.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain WSC PF01822.14 EJS42050.1 - 2.7e-10 40.0 12.9 2.7e-10 40.0 8.9 3.6 2 1 0 2 2 2 1 WSC domain LRR19-TM PF15176.1 EJS42050.1 - 5.7e-05 22.7 0.0 5.7e-05 22.7 0.0 3.1 3 1 0 3 3 3 1 Leucine-rich repeat family 19 TM domain EphA2_TM PF14575.1 EJS42050.1 - 0.0066 16.8 0.0 0.035 14.4 0.0 2.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 EJS42050.1 - 0.035 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM190 PF15431.1 EJS42050.1 - 0.37 10.7 0.0 0.37 10.7 0.0 3.4 3 1 1 4 4 4 0 Transmembrane protein 190 DUF912 PF06024.7 EJS42050.1 - 2.5 8.1 9.8 2.3e+02 1.8 6.8 3.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2217 PF10265.4 EJS42050.1 - 4.2 6.0 0.0 4.2 6.0 0.0 3.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) DUF936 PF06075.7 EJS42050.1 - 5.9 5.6 38.1 11 4.8 26.4 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Aha1_N PF09229.6 EJS42051.1 - 5.9e-34 116.8 0.0 7.4e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal UPF0556 PF10572.4 EJS42051.1 - 0.096 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 ERG4_ERG24 PF01222.12 EJS42052.1 - 3.2e-187 622.3 13.1 3.6e-187 622.1 9.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EJS42052.1 - 1.8e-06 27.4 0.9 1.8e-06 27.4 0.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Abhydrolase_1 PF00561.15 EJS42053.1 - 6.4e-78 261.4 0.0 7.9e-78 261.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EJS42053.1 - 4.7e-10 39.7 0.1 5e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EJS42053.1 - 0.00085 19.0 0.1 0.092 12.5 0.1 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family HCO3_cotransp PF00955.16 EJS42054.1 - 2.9e-57 194.4 13.8 3e-36 125.1 2.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family Sec2p PF06428.6 EJS42055.1 - 2e-29 101.3 11.8 2e-29 101.3 8.2 3.8 4 0 0 4 4 4 1 GDP/GTP exchange factor Sec2p Tubulin_C PF03953.12 EJS42055.1 - 0.05 13.6 0.2 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 Tubulin C-terminal domain FH2 PF02181.18 EJS42056.1 - 5.6e-86 288.7 7.1 5.6e-86 288.7 4.9 4.1 4 1 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EJS42056.1 - 2.7e-47 160.7 5.5 2.7e-47 160.7 3.8 4.2 4 1 2 6 6 6 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 EJS42056.1 - 3.4e-25 88.5 1.4 4.8e-19 68.4 0.1 5.8 6 0 0 6 6 6 2 Diaphanous GTPase-binding Domain AA_permease PF00324.16 EJS42057.1 - 7e-143 476.4 44.8 7.9e-143 476.2 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS42057.1 - 2.5e-32 111.9 50.3 4.1e-32 111.2 34.9 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EJS42058.1 - 3.8e-133 444.3 47.4 4.3e-133 444.1 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS42058.1 - 7.8e-31 107.0 51.8 9.6e-31 106.7 35.9 1.1 1 0 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.3 EJS42058.1 - 0.0028 17.0 4.4 0.16 11.3 0.5 3.1 2 0 0 2 2 2 2 Intrinsic membrane protein PufX PI3_PI4_kinase PF00454.22 EJS42059.1 - 6.4e-29 101.0 0.1 1.4e-28 99.9 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EJS42059.1 - 3.1e-22 78.0 2.2 8.5e-22 76.6 1.5 1.8 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 EJS42059.1 - 2.3e-06 26.8 0.7 7.3e-06 25.2 0.5 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CRAL_TRIO PF00650.15 EJS42060.1 - 8e-38 129.4 0.1 1.3e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EJS42060.1 - 7.1e-11 42.0 1.0 1.3e-10 41.2 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EJS42060.1 - 0.0021 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain YIF1 PF03878.10 EJS42061.1 - 1.4e-91 305.9 7.7 2.2e-91 305.2 5.3 1.3 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EJS42061.1 - 1.2e-06 28.1 2.7 2.7e-06 26.9 1.9 1.6 1 0 0 1 1 1 1 Yip1 domain ORC5_C PF14630.1 EJS42062.1 - 8.5e-64 215.6 1.1 1.2e-63 215.1 0.8 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.1 EJS42062.1 - 5.2e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EJS42062.1 - 0.00035 20.6 0.0 0.00088 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EJS42062.1 - 0.0069 16.2 0.2 0.027 14.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EJS42062.1 - 0.14 11.8 1.5 2.8 7.5 1.0 2.5 1 1 0 1 1 1 0 NACHT domain HMA PF00403.21 EJS42063.1 - 6.3e-10 39.0 0.1 7.6e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain E7 PF00527.13 EJS42063.1 - 0.049 13.7 0.4 0.079 13.1 0.3 1.4 1 1 0 1 1 1 0 E7 protein, Early protein Dsl1_C PF11989.3 EJS42064.1 - 8.5e-126 419.0 8.0 8.5e-126 419.0 5.6 3.7 4 0 0 4 4 4 1 Retrograde transport protein Dsl1 C terminal Dsl1_N PF11988.3 EJS42064.1 - 4.4e-124 413.9 23.2 6.8e-124 413.3 16.1 1.3 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 N terminal Mating_N PF12731.2 EJS42064.1 - 4 7.3 8.0 5.9 6.8 0.8 3.6 2 2 1 3 3 3 0 Mating-type protein beta 1 Pterin_bind PF00809.17 EJS42065.1 - 1.4e-41 142.1 0.2 4.9e-40 137.1 0.1 2.4 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EJS42065.1 - 2.5e-39 133.9 0.0 4.1e-38 129.9 0.0 2.5 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EJS42065.1 - 9.2e-37 125.6 0.5 3.5e-17 62.5 0.1 3.1 3 0 0 3 3 3 2 Dihydroneopterin aldolase zf-CCHC PF00098.18 EJS42066.1 - 1.3e-52 173.3 53.3 2.1e-08 33.7 1.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EJS42066.1 - 1e-10 41.1 45.1 0.0053 16.3 0.5 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EJS42066.1 - 4.3e-06 26.3 48.9 0.078 12.7 0.5 7.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.1 EJS42066.1 - 0.00014 21.3 43.1 0.2 11.1 0.4 7.1 4 3 3 7 7 7 6 Zinc knuckle WD40 PF00400.27 EJS42067.1 - 1.5e-11 43.6 11.8 6.1e-10 38.5 0.5 6.0 7 0 0 7 7 7 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EJS42067.1 - 0.00067 18.5 0.8 0.69 8.6 0.1 2.2 2 0 0 2 2 2 2 Coatomer WD associated region Hira PF07569.6 EJS42067.1 - 0.066 12.4 2.9 0.58 9.3 0.0 3.3 3 1 1 4 4 4 0 TUP1-like enhancer of split MRP-L46 PF11788.3 EJS42068.1 - 6.6e-36 123.3 0.2 1.1e-35 122.5 0.1 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 AAA_23 PF13476.1 EJS42069.1 - 5.8e-30 105.1 2.4 5.8e-30 105.1 1.6 8.4 1 1 6 7 7 7 1 AAA domain Rad50_zn_hook PF04423.9 EJS42069.1 - 3.4e-14 52.0 4.2 3.4e-14 52.0 2.9 4.8 4 0 0 4 4 4 1 Rad50 zinc hook motif SbcCD_C PF13558.1 EJS42069.1 - 4e-11 42.6 0.0 1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EJS42069.1 - 1.5e-07 30.9 0.1 1.5e-07 30.9 0.1 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EJS42069.1 - 3.9e-06 25.6 2.1 0.00015 20.4 0.0 6.8 3 1 3 6 6 6 3 AAA domain AAA_21 PF13304.1 EJS42069.1 - 0.00039 20.4 0.0 0.00039 20.4 0.0 7.2 2 1 2 4 4 4 1 AAA domain AAA_29 PF13555.1 EJS42069.1 - 0.00069 19.0 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EJS42069.1 - 0.0033 16.6 7.2 0.0033 16.6 5.0 6.9 2 2 3 7 7 7 2 Reovirus sigma C capsid protein POTRA_2 PF08479.6 EJS42069.1 - 0.067 12.8 2.9 37 4.0 0.0 5.2 4 1 0 5 5 5 0 POTRA domain, ShlB-type AAA_19 PF13245.1 EJS42069.1 - 0.24 11.1 0.0 0.61 9.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RNA_pol_I_A49 PF06870.7 EJS42070.1 - 4.2e-140 466.6 0.6 4.8e-140 466.5 0.4 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor tRNA-synt_1e PF01406.14 EJS42071.1 - 2.3e-145 483.3 0.6 2.3e-145 483.3 0.4 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EJS42071.1 - 1.6e-06 27.0 0.2 1.6e-06 27.0 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EJS42071.1 - 6.2e-05 21.1 0.0 6.2e-05 21.1 0.0 2.4 4 0 0 4 4 4 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 EJS42071.1 - 0.00028 19.6 0.3 0.00077 18.2 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (K) RNA_pol_Rpb1_3 PF04983.13 EJS42071.1 - 0.025 14.3 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 CWC25 PF12542.3 EJS42072.1 - 4.3e-15 55.9 1.4 4.3e-15 55.9 1.0 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing factor Cir_N PF10197.4 EJS42072.1 - 3e-13 49.5 8.2 3e-13 49.5 5.7 2.0 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF680 PF05079.7 EJS42072.1 - 0.0064 16.9 2.8 0.059 13.8 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF680) CemA PF03040.9 EJS42072.1 - 0.65 9.5 3.7 0.91 9.0 2.5 1.2 1 0 0 1 1 1 0 CemA family DUF342 PF03961.8 EJS42072.1 - 1.5 7.1 6.1 1.7 7.0 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.10 EJS42072.1 - 3.7 6.6 9.8 4.6 6.3 6.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2951 PF11166.3 EJS42072.1 - 4.8 7.0 12.5 0.54 10.1 5.3 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) DMAP1 PF05499.7 EJS42072.1 - 8.6 5.8 13.3 0.95 8.9 4.9 2.0 1 1 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF972 PF06156.8 EJS42072.1 - 9 6.7 10.4 4.6 7.6 5.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SUI1 PF01253.17 EJS42073.1 - 1.8e-28 98.1 1.1 2.3e-28 97.8 0.7 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 ANTH PF07651.11 EJS42074.1 - 1.2e-75 253.7 0.1 1.2e-75 253.7 0.1 2.9 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EJS42074.1 - 2.2e-59 199.7 6.6 2.2e-59 199.7 4.6 4.9 3 2 0 4 4 4 1 I/LWEQ domain ENTH PF01417.15 EJS42074.1 - 8.2e-05 22.4 2.8 0.00011 22.0 0.0 2.7 2 0 0 2 2 2 1 ENTH domain Fe_hyd_lg_C PF02906.9 EJS42075.1 - 8.4e-55 186.0 0.0 1.2e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Peptidase_C1_2 PF03051.10 EJS42076.1 - 1.7e-178 593.6 0.6 1.9e-178 593.4 0.4 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EJS42076.1 - 3.5e-06 27.0 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease Ytp1 PF10355.4 EJS42077.1 - 2.7e-78 262.9 17.8 5.5e-78 261.8 12.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) Globin PF00042.17 EJS42078.1 - 2.3e-05 24.6 0.0 4.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Globin EXOSC1 PF10447.4 EJS42080.1 - 3.1e-33 113.5 0.1 5.7e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 Brevenin PF03032.10 EJS42080.1 - 1.7 8.5 6.0 3 7.7 4.2 1.4 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family CRAL_TRIO PF00650.15 EJS42081.1 - 1.2e-38 132.0 0.0 1.8e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EJS42081.1 - 4.4e-12 45.9 1.3 1.5e-11 44.2 0.9 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Elongin_A PF06881.6 EJS42082.1 - 2.6e-26 92.1 17.2 1.6e-23 83.1 1.2 2.6 2 1 1 3 3 3 2 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4407 PF14362.1 EJS42082.1 - 0.15 11.0 0.7 0.2 10.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ARL2_Bind_BART PF11527.3 EJS42082.1 - 4.7 7.0 7.8 3.6 7.4 1.3 2.3 1 1 1 2 2 2 0 The ARF-like 2 binding protein BART GST_C PF00043.20 EJS42083.1 - 1.2e-22 79.6 0.0 2.6e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EJS42083.1 - 1.4e-16 60.4 0.0 2.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EJS42083.1 - 3.8e-09 36.4 0.0 9.7e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EJS42083.1 - 2.2e-08 34.1 0.0 4.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EJS42083.1 - 0.0011 18.7 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EJS42083.1 - 0.03 14.8 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_C54 PF03416.14 EJS42084.1 - 2.1e-90 302.6 0.0 2.7e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.8 EJS42085.1 - 3.2e-89 297.4 0.1 3.6e-89 297.2 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein LAP2alpha PF11560.3 EJS42085.1 - 0.046 12.9 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha POP1 PF06978.6 EJS42086.1 - 3.3e-65 219.2 14.4 1.1e-64 217.5 10.0 1.9 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EJS42086.1 - 1.2e-31 108.3 1.9 2.7e-31 107.2 1.3 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.6 EJS42086.1 - 0.025 14.5 0.0 0.074 13.0 0.0 1.8 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DASH_Dad4 PF08650.5 EJS42086.1 - 0.045 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad4 Adenylsucc_synt PF00709.16 EJS42087.1 - 2.5e-165 550.2 0.0 2.9e-165 550.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Glyco_transf_22 PF03901.12 EJS42088.1 - 4.8e-101 338.7 35.5 6.2e-101 338.4 24.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Rap1-DNA-bind PF09197.5 EJS42089.1 - 3.6e-43 146.3 9.8 3.1e-41 140.1 0.4 3.3 4 0 0 4 4 4 2 Rap1, DNA-binding Rap1_C PF11626.3 EJS42089.1 - 9.7e-25 86.2 0.0 9.2e-24 83.1 0.0 2.5 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 EJS42089.1 - 1e-08 35.0 1.7 1e-06 28.6 0.0 3.4 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EJS42089.1 - 1.4e-08 34.3 0.4 7.4e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_6 PF13921.1 EJS42089.1 - 6.1e-05 23.0 0.1 0.13 12.3 0.0 3.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain BRCT PF00533.21 EJS42089.1 - 0.0014 18.7 0.0 0.012 15.7 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PAPA-1 PF04795.7 EJS42090.1 - 1.9e-14 54.1 5.8 1.9e-14 54.1 4.1 3.0 4 0 0 4 4 4 1 PAPA-1-like conserved region DUF874 PF05917.6 EJS42090.1 - 0.0073 15.2 5.2 0.0073 15.2 3.6 1.8 1 1 1 2 2 2 1 Helicobacter pylori protein of unknown function (DUF874) DUF966 PF06136.8 EJS42090.1 - 0.56 9.5 16.1 0.84 8.9 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) rve_3 PF13683.1 EJS42091.1 - 0.054 13.0 0.8 0.16 11.4 0.1 2.0 2 0 0 2 2 2 0 Integrase core domain Neugrin PF06413.6 EJS42092.1 - 1.4e-06 28.3 1.2 1.9e-06 27.8 0.3 1.7 1 1 0 1 1 1 1 Neugrin Sigma70_r4 PF04545.11 EJS42092.1 - 0.00029 20.0 0.0 0.00063 18.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.1 EJS42092.1 - 0.0029 16.9 0.2 0.022 14.1 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EJS42092.1 - 0.0056 16.3 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_Tnp_ISL3 PF13542.1 EJS42092.1 - 0.026 13.6 0.0 0.061 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.7 EJS42092.1 - 0.034 13.7 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 HTH domain MarR PF01047.17 EJS42092.1 - 0.036 13.7 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_7 PF02796.10 EJS42092.1 - 0.061 13.1 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase MRP-L20 PF12824.2 EJS42092.1 - 0.069 13.1 9.8 0.24 11.3 6.8 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Mod_r PF07200.8 EJS42092.1 - 0.11 12.4 3.4 0.17 11.8 2.4 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HTH_23 PF13384.1 EJS42092.1 - 0.12 12.0 0.4 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain VID27 PF08553.5 EJS42093.1 - 0 1025.8 13.7 0 1024.9 9.5 1.4 1 1 0 1 1 1 1 VID27 cytoplasmic protein zf-DHHC PF01529.15 EJS42094.1 - 1.3e-31 109.3 16.0 1.3e-31 109.3 11.1 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase Syja_N PF02383.13 EJS42095.1 - 3.5e-92 308.5 0.2 3.5e-92 308.5 0.1 2.1 2 0 0 2 2 2 1 SacI homology domain CDC50 PF03381.10 EJS42096.1 - 3.9e-91 305.0 1.3 5.2e-91 304.6 0.9 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family RNase_H2_suC PF08615.6 EJS42096.1 - 0.069 12.9 0.2 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Na_Ca_ex PF01699.19 EJS42097.1 - 1.7e-26 92.4 29.1 6.2e-18 64.7 6.5 3.4 4 1 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EJS42097.1 - 5.8e-16 58.6 5.5 5.8e-16 58.6 3.8 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF307) Abhydrolase_5 PF12695.2 EJS42098.1 - 4.6e-17 62.1 0.0 6.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EJS42098.1 - 2.3e-12 47.2 0.0 3.3e-10 40.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EJS42098.1 - 2.4e-08 33.8 0.0 0.00051 19.6 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EJS42098.1 - 1.5e-05 24.3 0.0 0.00014 21.1 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EJS42098.1 - 0.0015 18.2 0.0 0.068 12.8 0.0 2.2 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EJS42098.1 - 0.0021 17.5 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 EJS42098.1 - 0.0042 16.9 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EJS42098.1 - 0.0088 15.5 0.0 1.5 8.1 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.15 EJS42098.1 - 0.15 11.4 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_9 PF10081.4 EJS42098.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Sugar_tr PF00083.19 EJS42099.1 - 8.7e-111 370.6 33.9 1e-110 370.4 23.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS42099.1 - 1e-24 86.9 25.9 1.9e-21 76.1 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SPC25 PF06703.6 EJS42099.1 - 0.086 12.4 0.6 1.2 8.7 0.0 3.0 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF932 PF06067.6 EJS42099.1 - 0.25 10.5 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) UNC-93 PF05978.11 EJS42099.1 - 1.8 8.0 32.5 0.015 14.7 2.0 4.4 3 1 1 4 4 4 0 Ion channel regulatory protein UNC-93 WD40 PF00400.27 EJS42100.1 - 3.3e-42 140.8 8.9 2.5e-10 39.8 0.2 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EJS42100.1 - 6.7e-06 25.9 2.0 0.034 13.8 0.1 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EJS42100.1 - 0.0011 18.4 0.0 0.36 10.3 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PDT PF00800.13 EJS42101.1 - 1.1e-55 187.9 0.1 1.4e-55 187.6 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EJS42101.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 ACT domain ATP11 PF06644.6 EJS42102.1 - 3.9e-98 328.2 3.5 4.9e-98 327.8 2.4 1.0 1 0 0 1 1 1 1 ATP11 protein Myb_DNA-bind_5 PF13873.1 EJS42103.1 - 0.0085 15.9 1.3 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EJS42103.1 - 0.046 14.3 0.3 0.13 12.8 0.0 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain TPR_11 PF13414.1 EJS42104.1 - 4.2e-12 45.5 6.0 3.3e-10 39.4 0.3 4.5 3 2 2 5 5 5 2 TPR repeat TPR_16 PF13432.1 EJS42104.1 - 3.4e-08 33.9 1.4 0.076 13.7 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EJS42104.1 - 2.4e-07 30.5 1.2 0.031 14.2 0.2 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EJS42104.1 - 1.6e-06 28.2 2.5 0.11 13.1 0.0 5.7 4 2 2 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EJS42104.1 - 2.8e-05 23.5 5.6 0.067 12.8 0.1 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EJS42104.1 - 3e-05 23.4 7.8 0.0089 15.7 0.3 4.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EJS42104.1 - 3.3e-05 24.1 4.0 0.019 15.3 0.1 3.9 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EJS42104.1 - 0.00019 21.1 9.8 0.0037 17.0 0.2 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EJS42104.1 - 0.0019 18.2 0.6 0.037 14.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EJS42104.1 - 0.0028 17.3 3.3 0.15 11.9 0.1 4.9 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EJS42104.1 - 0.0069 15.4 1.8 0.28 10.1 0.4 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 EJS42104.1 - 0.02 14.3 3.2 0.12 11.7 0.0 3.2 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_9 PF13371.1 EJS42104.1 - 0.02 14.7 0.1 0.16 11.8 0.0 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EJS42104.1 - 0.032 14.3 4.7 0.46 10.6 0.6 3.3 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EJS42104.1 - 0.07 13.1 1.2 0.93 9.6 0.0 3.4 4 0 0 4 4 3 0 PPR repeat Pkinase PF00069.20 EJS42106.1 - 2e-59 200.8 0.0 2.4e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42106.1 - 2.3e-29 102.2 0.0 3.1e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS42106.1 - 2.2e-05 23.5 0.0 0.00027 20.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EJS42106.1 - 0.00038 20.2 0.0 0.0032 17.2 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EJS42106.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EJS42106.1 - 0.033 13.2 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S11 PF00411.14 EJS42107.1 - 6.3e-06 26.3 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Bax1-I PF01027.15 EJS42108.1 - 4e-37 127.8 17.9 7.8e-37 126.8 12.4 1.4 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MerC PF03203.9 EJS42108.1 - 0.0046 17.3 2.1 0.0046 17.3 1.5 2.9 2 1 1 3 3 3 1 MerC mercury resistance protein DUF2919 PF11143.3 EJS42108.1 - 0.089 12.6 14.5 0.19 11.5 5.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) Ras PF00071.17 EJS42109.1 - 1.6e-29 102.3 1.8 8.7e-25 86.9 1.2 2.6 2 1 0 2 2 2 2 Ras family Miro PF08477.8 EJS42109.1 - 4.7e-13 49.6 0.3 2.1e-09 37.8 0.2 2.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS42109.1 - 9.4e-07 28.2 2.1 1.9e-05 23.9 0.9 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EJS42109.1 - 0.00054 19.4 1.4 0.01 15.2 1.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EJS42109.1 - 0.0059 16.5 0.1 0.069 13.1 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Kdo PF06293.9 EJS42109.1 - 0.019 14.0 0.1 0.044 12.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_11 PF13086.1 EJS42109.1 - 0.042 13.4 0.6 0.074 12.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EJS42109.1 - 0.062 12.8 0.1 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EJS42109.1 - 0.14 11.5 0.4 0.79 9.1 0.0 2.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF1947 PF09183.5 EJS42109.1 - 0.52 10.1 2.8 7.8 6.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) Pkinase PF00069.20 EJS42110.1 - 7.9e-65 218.5 0.0 7.9e-65 218.5 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42110.1 - 9.2e-50 169.1 0.0 9.2e-50 169.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EJS42110.1 - 1.8e-21 76.3 0.3 1.8e-21 76.3 0.2 3.5 3 0 0 3 3 3 1 P21-Rho-binding domain PH PF00169.24 EJS42110.1 - 9e-12 45.1 1.8 2.4e-11 43.7 0.7 2.1 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 EJS42110.1 - 2.8e-07 29.7 0.0 6.8e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EJS42110.1 - 0.0037 17.4 1.0 0.0037 17.4 0.7 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain APH PF01636.18 EJS42110.1 - 0.083 12.6 0.0 0.083 12.6 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Sec7_N PF12783.2 EJS42111.1 - 6e-37 126.6 5.2 6e-37 126.6 3.6 4.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Pet20 PF08692.5 EJS42112.1 - 6.3e-10 39.1 0.1 2.2e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial protein Pet20 PalH PF08733.5 EJS42113.1 - 1.2e-95 320.3 17.7 1.6e-95 319.9 12.3 1.1 1 0 0 1 1 1 1 PalH/RIM21 Nucleoplasmin PF03066.10 EJS42113.1 - 0.14 11.6 3.3 0.26 10.8 2.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EJS42113.1 - 3.3 6.8 7.5 4.9 6.3 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein RabGAP-TBC PF00566.13 EJS42114.1 - 1.5e-45 155.2 6.1 2.4e-44 151.3 4.2 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TruB_N PF01509.13 EJS42115.1 - 3.7e-41 140.7 0.8 3.7e-39 134.2 0.0 2.7 3 0 0 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) Mid1 PF12929.2 EJS42116.1 - 1.3e-137 458.9 24.1 1.7e-137 458.6 16.7 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fer2_4 PF13510.1 EJS42116.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Cyclin_N PF00134.18 EJS42117.1 - 9.8e-22 76.8 0.0 1.8e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EJS42117.1 - 8.2e-12 45.7 0.0 1.4e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin Rcd1 PF04078.8 EJS42118.1 - 5e-120 399.2 3.4 5.8e-120 399.0 2.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Adaptin_N PF01602.15 EJS42119.1 - 2.7e-121 405.5 14.1 3.3e-121 405.1 9.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EJS42119.1 - 2.6e-49 166.8 1.1 5.8e-49 165.7 0.7 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EJS42119.1 - 2.9e-11 43.5 2.5 0.0029 17.8 0.1 4.9 2 1 4 6 6 6 4 HEAT repeats HEAT PF02985.17 EJS42119.1 - 0.00051 19.9 4.2 4.9 7.4 0.0 6.5 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.2 EJS42119.1 - 0.0018 18.1 10.2 0.028 14.2 0.1 3.8 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EJS42119.1 - 0.12 12.8 4.0 0.44 11.1 0.1 3.8 3 2 0 3 3 3 0 HEAT-like repeat Hist_deacetyl PF00850.14 EJS42120.1 - 2.7e-81 273.2 0.0 3.8e-81 272.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain AAA PF00004.24 EJS42121.1 - 3.6e-57 192.2 0.0 6e-46 155.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EJS42121.1 - 1.5e-05 25.8 0.0 0.0049 17.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EJS42121.1 - 2.3e-05 24.3 0.0 0.00026 20.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EJS42121.1 - 0.0003 20.2 0.2 0.0069 15.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 EJS42121.1 - 0.00041 19.3 0.0 0.00092 18.1 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RuvB_N PF05496.7 EJS42121.1 - 0.00045 19.3 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EJS42121.1 - 0.001 19.1 0.0 0.017 15.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EJS42121.1 - 0.0023 18.1 0.0 0.012 15.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 EJS42121.1 - 0.0023 17.6 0.0 0.01 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EJS42121.1 - 0.0027 17.1 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EJS42121.1 - 0.0029 17.6 0.2 0.061 13.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EJS42121.1 - 0.004 17.0 0.0 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EJS42121.1 - 0.01 14.9 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 0 KaiC TIP49 PF06068.8 EJS42121.1 - 0.012 14.3 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_19 PF13245.1 EJS42121.1 - 0.018 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EJS42121.1 - 0.022 13.9 0.1 0.042 13.0 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EJS42121.1 - 0.062 13.6 0.1 0.34 11.2 0.0 2.3 3 0 0 3 3 2 0 AAA domain PhoH PF02562.11 EJS42121.1 - 0.084 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 EJS42121.1 - 0.11 12.0 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.5 EJS42121.1 - 0.48 10.3 3.1 0.66 9.9 0.1 2.8 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain DnaJ PF00226.26 EJS42122.1 - 3.2e-07 29.9 0.2 5.2e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EJS42122.1 - 0.024 14.4 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Pam16 Osmo_CC PF08946.5 EJS42122.1 - 0.91 9.6 4.4 12 6.0 1.0 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Sugar_tr PF00083.19 EJS42123.1 - 4.3e-121 404.6 24.5 4.9e-121 404.4 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS42123.1 - 1.8e-25 89.4 24.8 2.8e-24 85.4 10.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FA_desaturase PF00487.19 EJS42123.1 - 2.5 7.4 6.3 2.2 7.6 1.4 2.4 2 0 0 2 2 2 0 Fatty acid desaturase Pkinase PF00069.20 EJS42124.1 - 2.2e-71 240.0 0.0 6.3e-71 238.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42124.1 - 2.2e-33 115.4 0.0 9e-33 113.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS42124.1 - 2.5e-06 26.6 0.0 1.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EJS42124.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family AA_permease PF00324.16 EJS42125.1 - 9.9e-128 426.4 33.5 1.1e-127 426.2 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS42125.1 - 3.9e-30 104.7 33.6 4.7e-30 104.4 23.3 1.0 1 0 0 1 1 1 1 Amino acid permease OapA_N PF08525.6 EJS42125.1 - 0.2 11.4 2.7 0.32 10.8 0.2 2.8 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif Rad60-SLD PF11976.3 EJS42126.1 - 1.1e-20 73.0 0.6 2e-20 72.2 0.2 1.5 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EJS42126.1 - 6.6e-13 47.8 0.1 8.6e-13 47.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EJS42126.1 - 0.058 13.1 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Complex1_LYR PF05347.10 EJS42127.1 - 6.7e-11 41.8 0.1 1.9e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EJS42127.1 - 5.5e-10 39.2 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EJS42127.1 - 0.00012 22.5 0.1 0.00016 22.0 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like HBS1_N PF08938.5 EJS42127.1 - 0.031 14.4 1.1 0.04 14.0 0.8 1.4 1 1 0 1 1 1 0 HBS1 N-terminus Pox_D2 PF04701.8 EJS42127.1 - 0.067 13.1 0.2 4.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Pox virus D2 protein CSTF2_hinge PF14327.1 EJS42127.1 - 0.22 11.6 0.9 0.41 10.7 0.1 1.8 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Glutaredoxin PF00462.19 EJS42128.1 - 4.1e-15 55.5 0.0 6.4e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 EJS42128.1 - 0.0012 18.5 0.3 0.044 13.5 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin domain Thioredoxin_9 PF14595.1 EJS42128.1 - 0.016 14.7 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin IMD PF08397.6 EJS42129.1 - 0.028 13.7 1.0 0.05 12.9 0.7 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain La PF05383.12 EJS42130.1 - 6.2e-21 73.9 0.1 1.3e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 La domain Macoilin PF09726.4 EJS42130.1 - 0.11 10.8 12.8 0.1 10.8 8.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Phage_Mu_F PF04233.9 EJS42130.1 - 1.1 9.7 7.5 2.9 8.4 5.2 1.7 1 1 0 1 1 1 0 Phage Mu protein F like protein Hexokinase_2 PF03727.11 EJS42131.1 - 4.8e-85 284.6 0.0 6.6e-85 284.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EJS42131.1 - 2.5e-67 226.1 0.0 3.7e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Thioredoxin PF00085.15 EJS42132.1 - 3.4e-37 126.2 0.1 6.2e-19 67.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EJS42132.1 - 2.8e-14 53.3 2.4 1.1e-12 48.1 0.5 3.1 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EJS42132.1 - 7.8e-07 29.1 0.2 0.088 12.9 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EJS42132.1 - 0.00041 20.3 0.1 0.21 11.6 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Calsequestrin PF01216.12 EJS42132.1 - 0.0013 17.5 0.1 0.0025 16.6 0.1 1.4 1 0 0 1 1 1 1 Calsequestrin Pyr_excise PF03013.9 EJS42132.1 - 0.05 13.3 0.2 0.65 9.7 0.0 2.4 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase FKBP_C PF00254.23 EJS42133.1 - 6.7e-34 115.7 0.0 9e-34 115.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Zn_clus PF00172.13 EJS42134.1 - 1e-05 25.3 6.3 2.1e-05 24.3 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KH_3 PF13014.1 EJS42134.1 - 0.046 13.3 0.7 0.12 12.0 0.5 1.7 1 0 0 1 1 1 0 KH domain KH_1 PF00013.24 EJS42134.1 - 0.15 11.7 0.7 0.32 10.6 0.5 1.5 1 0 0 1 1 1 0 KH domain LT-IIB PF06453.6 EJS42135.1 - 0.042 13.5 1.3 0.045 13.4 0.7 1.2 1 1 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) QCR10 PF09796.4 EJS42135.1 - 0.73 9.5 8.6 0.084 12.5 3.0 1.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Pmp3 PF01679.12 EJS42136.1 - 8.3e-21 73.4 7.3 9.5e-21 73.2 5.1 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Claudin_2 PF13903.1 EJS42136.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction RPAP1_C PF08620.5 EJS42137.1 - 5.9e-32 109.3 0.1 1.2e-31 108.4 0.1 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EJS42137.1 - 1.6e-14 53.2 3.5 1.6e-14 53.2 2.4 2.0 2 0 0 2 2 2 1 RPAP1-like, N-terminal UCR_14kD PF02271.11 EJS42139.1 - 2.7e-44 149.2 0.1 3.1e-44 149.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF1216 PF06746.6 EJS42140.1 - 0.02 14.6 9.0 0.035 13.8 1.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1216) HALZ PF02183.13 EJS42140.1 - 1 9.1 7.8 3 7.6 3.0 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF349 PF03993.7 EJS42140.1 - 1.8 8.7 10.0 4.1 7.6 0.4 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) PCI PF01399.22 EJS42141.1 - 2.8e-14 53.2 2.5 3.6e-14 52.9 0.5 2.2 2 0 0 2 2 2 1 PCI domain Foie-gras_1 PF11817.3 EJS42141.1 - 0.0014 18.1 0.1 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 DUF4080 PF13311.1 EJS42141.1 - 0.051 13.6 0.1 0.051 13.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4080) MRP-L46 PF11788.3 EJS42141.1 - 0.1 13.2 0.6 12 6.5 0.0 2.4 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 TPR_19 PF14559.1 EJS42141.1 - 0.27 11.6 2.3 2 8.8 1.5 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat eIF3g PF12353.3 EJS42142.1 - 3.9e-42 143.1 0.6 5.6e-42 142.6 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EJS42142.1 - 3.3e-11 42.6 0.0 5.5e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS42142.1 - 2.5e-09 36.9 0.0 4.4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS42142.1 - 2.2e-06 27.4 0.0 4.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) M16C_assoc PF08367.6 EJS42143.1 - 1.1e-81 273.3 0.6 2.5e-81 272.1 0.2 1.8 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EJS42143.1 - 6.7e-33 113.9 0.1 1.5e-16 60.6 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EJS42143.1 - 2.4e-06 27.3 0.0 1.5e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RRM_1 PF00076.17 EJS42144.1 - 3e-29 100.4 0.2 1.4e-17 63.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS42144.1 - 2.2e-16 59.5 0.0 5.2e-11 42.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS42144.1 - 5.2e-10 39.0 0.0 2e-09 37.1 0.0 2.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EJS42144.1 - 0.037 14.0 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain PIG-S PF10510.4 EJS42145.1 - 2e-145 485.4 5.2 2.3e-145 485.1 3.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein LCM PF04072.9 EJS42146.1 - 3.6e-29 101.6 0.0 4.7e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase HTH_44 PF14641.1 EJS42146.1 - 0.086 12.8 0.2 0.31 11.0 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 Metallophos PF00149.23 EJS42147.1 - 3.7e-38 130.9 0.2 5.3e-38 130.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PIG-P PF08510.7 EJS42148.1 - 2.2e-33 114.5 2.8 2.5e-33 114.3 1.9 1.0 1 0 0 1 1 1 1 PIG-P LRS4 PF10422.4 EJS42149.1 - 3.1e-58 197.0 17.7 3.1e-58 197.0 12.3 2.0 2 0 0 2 2 2 1 Monopolin complex subunit LRS4 DOT1 PF08123.8 EJS42150.1 - 3.5e-92 307.3 1.1 5.7e-92 306.6 0.8 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.15 EJS42150.1 - 0.0092 15.0 0.1 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Pribosyltran PF00156.22 EJS42151.1 - 8.1e-18 64.3 0.0 1.1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EJS42151.1 - 0.002 17.3 0.0 0.0033 16.6 0.0 1.4 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Med13_C PF06333.7 EJS42152.1 - 4.6e-90 302.1 12.7 5.2e-58 196.5 2.4 3.0 2 1 1 3 3 3 2 Mediator complex subunit 13 C-terminal ZZ PF00569.12 EJS42153.1 - 3.2e-18 65.0 7.9 5.3e-18 64.2 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 EJS42153.1 - 2.6e-11 43.4 0.4 1.1e-09 38.2 0.0 2.6 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EJS42153.1 - 5.4e-09 35.9 0.1 1.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EJS42153.1 - 0.0002 21.3 0.2 0.00073 19.5 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain U3_assoc_6 PF08640.6 EJS42154.1 - 9.9e-34 114.9 5.7 5.8e-33 112.4 0.4 3.2 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 EJS42154.1 - 6.6e-05 21.9 6.8 0.00078 18.4 0.7 2.7 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference DUF2250 PF10007.4 EJS42154.1 - 0.024 14.5 1.5 1.9 8.4 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) TPR_17 PF13431.1 EJS42154.1 - 0.038 14.1 1.1 9.6 6.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EJS42154.1 - 0.069 13.8 0.0 2 9.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HAT PF02184.11 EJS42154.1 - 0.097 12.4 0.3 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat Suf PF05843.9 EJS42154.1 - 2.2 7.9 16.4 0.026 14.2 2.1 3.8 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) Homeobox PF00046.24 EJS42155.1 - 2.9e-17 62.0 0.9 5.7e-17 61.0 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EJS42155.1 - 0.034 13.8 0.2 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 Homeobox KN domain Metallophos PF00149.23 EJS42156.1 - 7.2e-15 54.9 0.2 1.4e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NDUF_B8 PF05821.6 EJS42156.1 - 0.014 15.1 1.4 0.031 13.9 1.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Peptidase_S49_N PF08496.5 EJS42156.1 - 3.9 7.2 6.0 21 4.8 0.6 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AhpC-TSA PF00578.16 EJS42157.1 - 3.2e-34 117.2 0.0 2.8e-33 114.2 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EJS42157.1 - 5.2e-19 68.2 0.1 8.1e-19 67.6 0.0 1.3 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.4 EJS42157.1 - 1.6e-10 40.4 0.2 2.9e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Guanylate_kin PF00625.16 EJS42158.1 - 5e-70 234.6 0.0 5.5e-70 234.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EJS42158.1 - 1.3e-06 28.2 0.0 2.6e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EJS42158.1 - 4.6e-06 26.8 0.0 8.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EJS42158.1 - 1.1e-05 25.7 0.0 5.7e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EJS42158.1 - 2.2e-05 24.5 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EJS42158.1 - 2.3e-05 25.2 0.0 3.4e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EJS42158.1 - 0.00036 20.4 0.0 0.00072 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EJS42158.1 - 0.00055 20.4 0.0 0.0011 19.4 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EJS42158.1 - 0.00058 20.1 0.0 0.00092 19.5 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 EJS42158.1 - 0.0013 18.7 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EJS42158.1 - 0.0014 17.8 0.0 0.0024 17.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EJS42158.1 - 0.0021 17.7 0.0 0.0053 16.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EJS42158.1 - 0.0023 18.0 0.0 0.0047 17.0 0.0 1.7 1 1 0 1 1 1 1 RNA helicase AAA_29 PF13555.1 EJS42158.1 - 0.0025 17.3 1.5 0.012 15.1 0.1 2.3 2 1 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EJS42158.1 - 0.0029 17.2 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 EJS42158.1 - 0.0053 16.7 0.0 0.0088 15.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EJS42158.1 - 0.0061 16.2 0.1 0.0072 16.0 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EJS42158.1 - 0.0082 16.3 0.0 0.016 15.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EJS42158.1 - 0.0083 15.7 0.6 0.11 12.0 0.2 2.3 2 1 1 3 3 3 1 AAA domain T2SE PF00437.15 EJS42158.1 - 0.0085 15.0 0.1 0.037 12.9 0.0 1.9 1 1 1 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 EJS42158.1 - 0.0095 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain NTPase_1 PF03266.10 EJS42158.1 - 0.016 14.8 0.1 0.022 14.4 0.0 1.4 1 1 0 1 1 1 0 NTPase AAA_30 PF13604.1 EJS42158.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EJS42158.1 - 0.02 13.9 0.0 0.031 13.2 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EJS42158.1 - 0.047 13.0 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EJS42158.1 - 0.05 13.3 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EJS42158.1 - 0.052 13.0 0.0 0.13 11.7 0.0 1.7 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EJS42158.1 - 0.058 12.3 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Rad17 PF03215.10 EJS42158.1 - 0.061 12.0 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein cobW PF02492.14 EJS42158.1 - 0.061 12.7 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EJS42158.1 - 0.063 13.0 0.1 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EJS42158.1 - 0.066 13.5 3.4 0.19 12.0 2.3 2.0 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EJS42158.1 - 0.083 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Na_H_Exchanger PF00999.16 EJS42159.1 - 1.4e-66 224.6 35.0 1.8e-66 224.2 24.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.1 EJS42159.1 - 0.02 14.4 2.5 0.067 12.7 0.5 2.4 2 0 0 2 2 2 0 Myc target protein 1 HECT PF00632.20 EJS42160.1 - 1.6e-90 303.5 0.1 1.6e-90 303.5 0.1 3.0 4 0 0 4 4 4 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EJS42160.1 - 8.7e-80 268.4 3.9 8.7e-80 268.4 2.7 2.9 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 EJS42160.1 - 2.2e-44 151.7 2.0 3.8e-44 150.9 0.1 2.5 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 EJS42160.1 - 1.8e-14 53.5 0.2 9.1e-14 51.2 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) MSC PF09402.5 EJS42161.1 - 2.2e-89 299.4 7.6 2.2e-89 299.4 5.3 1.9 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EJS42161.1 - 8e-16 57.2 5.1 1.3e-15 56.6 0.2 2.7 2 0 0 2 2 2 1 HeH/LEM domain MAT1 PF06391.8 EJS42162.1 - 3.3e-69 232.4 27.8 4.4e-69 232.0 19.3 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.1 EJS42162.1 - 0.0014 18.2 5.4 0.0024 17.5 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EJS42162.1 - 0.0024 17.8 6.9 0.0074 16.2 4.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EJS42162.1 - 0.0061 16.3 5.8 0.019 14.8 4.2 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EJS42162.1 - 0.014 15.0 6.5 0.058 13.0 4.6 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EJS42162.1 - 0.03 14.0 8.5 0.19 11.4 6.0 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-piccolo PF05715.8 EJS42162.1 - 0.17 11.9 1.2 0.44 10.5 0.9 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger RasGEF_N PF00618.15 EJS42162.1 - 0.44 10.6 3.3 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 RasGEF N-terminal motif zf-RING_4 PF14570.1 EJS42162.1 - 0.96 9.0 9.4 11 5.6 6.5 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EJS42162.1 - 1.2 8.8 6.8 0.93 9.2 3.1 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Tub_2 PF04525.7 EJS42163.1 - 0.017 14.5 0.0 0.017 14.5 0.0 1.0 1 0 0 1 1 1 0 Tubby C 2 Orthopox_F8 PF05886.6 EJS42164.1 - 0.17 11.7 0.1 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 Orthopoxvirus F8 protein MRP-L28 PF09812.4 EJS42165.1 - 2.3e-44 150.9 2.5 2.6e-44 150.8 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 zf-C2H2 PF00096.21 EJS42166.1 - 5.3e-06 26.4 9.3 0.00076 19.6 1.4 3.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS42166.1 - 0.0022 18.2 1.0 0.0022 18.2 0.7 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EJS42166.1 - 0.0028 17.8 10.4 0.012 15.9 0.3 3.8 3 0 0 3 3 3 1 Zinc-finger double domain Prp31_C PF09785.4 EJS42166.1 - 0.0041 17.5 1.5 0.0041 17.5 1.0 2.3 3 0 0 3 3 3 1 Prp31 C terminal domain zf-BED PF02892.10 EJS42166.1 - 0.052 13.3 5.1 0.04 13.6 1.2 2.6 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EJS42166.1 - 0.13 12.1 3.3 2.9 7.9 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EJS42166.1 - 2.2 8.5 9.2 11 6.3 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EJS42166.1 - 6.9 7.1 19.9 1 9.7 0.3 4.8 5 0 0 5 5 5 0 C2H2-type zinc-finger domain DUF3020 PF11223.3 EJS42167.1 - 7e-13 48.7 30.7 3.4e-11 43.3 2.9 8.6 8 1 0 8 8 8 2 Protein of unknown function (DUF3020) Methyltransf_11 PF08241.7 EJS42168.1 - 0.042 14.3 0.0 0.09 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EJS42168.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase PAS_4 PF08448.5 EJS42168.1 - 0.13 12.2 0.0 0.4 10.7 0.0 1.9 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.20 EJS42169.1 - 1.9e-59 200.9 0.0 2.8e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42169.1 - 1.7e-28 99.3 0.0 3.1e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS42169.1 - 2.2e-08 33.3 0.0 3.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EJS42169.1 - 0.00063 19.5 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.3 EJS42169.1 - 0.01 15.2 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 RIO1 PF01163.17 EJS42169.1 - 0.041 13.2 0.3 0.13 11.6 0.2 1.8 1 1 0 1 1 1 0 RIO1 family SNARE PF05739.14 EJS42170.1 - 7.9e-15 54.3 4.1 7.9e-15 54.3 2.8 3.7 4 0 0 4 4 4 1 SNARE domain Syntaxin-6_N PF09177.6 EJS42170.1 - 1.7e-06 28.3 4.5 1.7e-06 28.3 3.1 2.7 2 1 1 3 3 3 1 Syntaxin 6, N-terminal Sec3_C PF09763.4 EJS42170.1 - 0.00046 18.4 1.2 0.00064 17.9 0.3 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec3 APG17 PF04108.7 EJS42170.1 - 0.042 12.6 7.4 0.2 10.3 2.8 2.7 1 1 1 2 2 2 0 Autophagy protein Apg17 Myosin_tail_1 PF01576.14 EJS42170.1 - 0.11 10.1 12.3 0.14 9.8 8.6 1.1 1 0 0 1 1 1 0 Myosin tail Sec20 PF03908.8 EJS42170.1 - 0.15 11.8 1.3 0.49 10.1 0.0 2.3 2 1 2 4 4 4 0 Sec20 Syntaxin PF00804.20 EJS42170.1 - 0.16 12.1 12.9 0.93 9.6 7.1 2.5 2 1 0 2 2 2 0 Syntaxin DUF724 PF05266.9 EJS42170.1 - 0.27 10.8 6.4 0.19 11.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GrpE PF01025.14 EJS42170.1 - 0.36 10.3 7.6 0.051 13.1 1.9 2.0 2 0 0 2 2 2 0 GrpE RmuC PF02646.11 EJS42170.1 - 0.49 9.1 9.1 0.19 10.5 0.3 2.8 2 1 0 3 3 3 0 RmuC family Cob_adeno_trans PF01923.13 EJS42170.1 - 0.59 9.8 3.6 0.25 11.1 0.6 1.8 2 1 0 2 2 2 0 Cobalamin adenosyltransferase PBC PF03792.8 EJS42170.1 - 0.67 9.6 6.6 0.18 11.4 0.4 2.4 2 1 0 2 2 2 0 PBC domain Allexi_40kDa PF05549.6 EJS42170.1 - 0.7 9.1 7.9 0.39 9.9 2.4 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Nup88 PF10168.4 EJS42170.1 - 0.75 7.5 8.5 0.17 9.7 0.1 2.0 2 0 0 2 2 2 0 Nuclear pore component Pex19 PF04614.7 EJS42170.1 - 0.92 9.0 12.4 0.52 9.8 0.2 2.1 1 1 1 2 2 2 0 Pex19 protein family CHASE3 PF05227.8 EJS42170.1 - 0.94 9.1 10.7 0.11 12.2 3.7 2.0 2 0 0 2 2 2 0 CHASE3 domain DUF892 PF05974.7 EJS42170.1 - 1 9.1 4.3 3.1 7.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF892) Syntaxin_2 PF14523.1 EJS42170.1 - 2.1 8.4 8.5 4.1 7.5 2.8 2.8 2 1 0 2 2 2 0 Syntaxin-like protein Hrs_helical PF12210.3 EJS42170.1 - 2.3 8.5 10.5 6.2 7.1 2.6 2.9 2 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CR6_interact PF10147.4 EJS42170.1 - 4.6 6.4 7.0 0.26 10.5 1.1 1.6 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Spectrin PF00435.16 EJS42170.1 - 5.6 7.3 9.0 4.1 7.7 2.0 2.5 2 1 0 2 2 2 0 Spectrin repeat DUF4164 PF13747.1 EJS42170.1 - 6.4 6.9 9.8 4.6 7.4 2.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Snf7 PF03357.16 EJS42170.1 - 8.9 5.6 16.0 0.89 8.9 1.8 2.8 1 1 0 2 2 2 0 Snf7 Mito_carr PF00153.22 EJS42171.1 - 1.8e-12 46.7 0.1 0.00039 20.0 0.0 4.1 4 0 0 4 4 4 3 Mitochondrial carrier protein NBP1 PF08537.5 EJS42171.1 - 0.095 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 TRAPP PF04051.11 EJS42172.1 - 2.1e-52 176.6 0.0 2.9e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Rpr2 PF04032.11 EJS42174.1 - 4.3e-14 52.1 0.7 4.3e-14 52.1 0.5 1.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain GFA PF04828.9 EJS42174.1 - 0.19 11.7 1.9 1.1 9.2 0.1 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Baculo_ME53 PF06061.6 EJS42174.1 - 0.27 10.1 2.9 1 8.2 1.8 2.0 1 1 0 1 1 1 0 Baculoviridae ME53 zf-ribbon_3 PF13248.1 EJS42174.1 - 0.96 8.7 4.8 1.6 8.0 1.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Pex24p PF06398.6 EJS42175.1 - 8.7e-87 291.2 10.7 1.1e-86 290.8 7.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Alk_phosphatase PF00245.15 EJS42177.1 - 1.4e-152 508.2 0.3 1.7e-152 508.0 0.2 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EJS42177.1 - 0.0001 21.8 0.0 0.00027 20.3 0.0 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily cwf21 PF08312.7 EJS42178.1 - 9.4e-17 60.5 3.1 1.7e-16 59.7 2.1 1.4 1 0 0 1 1 1 1 cwf21 domain Trans_reg_C PF00486.23 EJS42178.1 - 0.017 15.0 0.2 0.19 11.6 0.1 2.2 1 1 0 1 1 1 0 Transcriptional regulatory protein, C terminal 2CSK_N PF08521.5 EJS42178.1 - 0.11 12.0 0.3 0.17 11.4 0.2 1.3 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal YukD PF08817.5 EJS42178.1 - 0.11 13.0 0.9 1.7 9.2 0.1 2.5 1 1 2 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD TLE_N PF03920.10 EJS42178.1 - 0.3 10.9 4.3 0.12 12.1 0.8 1.8 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Seryl_tRNA_N PF02403.17 EJS42178.1 - 1.1 9.3 6.3 2.7 8.0 2.0 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Vps52 PF04129.7 EJS42179.1 - 1e-193 644.5 19.6 1.3e-193 644.1 13.6 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family YL1 PF05764.8 EJS42180.1 - 2.2e-59 200.9 37.0 2.2e-59 200.9 25.7 2.6 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 EJS42180.1 - 2.9e-14 52.3 0.5 5.6e-14 51.3 0.3 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Snf7 PF03357.16 EJS42181.1 - 2.2e-39 134.6 25.5 2.6e-39 134.3 17.7 1.1 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 EJS42181.1 - 0.0016 18.4 15.3 0.0016 18.4 10.6 2.1 1 1 1 2 2 2 1 YlqD protein TrfA PF07042.6 EJS42181.1 - 0.039 12.7 0.9 0.054 12.3 0.6 1.3 1 0 0 1 1 1 0 TrfA protein Fmp27_SW PF10305.4 EJS42181.1 - 0.042 14.2 1.2 0.12 12.7 0.0 2.3 2 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain V_ATPase_I PF01496.14 EJS42181.1 - 0.068 11.0 9.4 0.088 10.6 6.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.6 EJS42181.1 - 0.54 10.1 8.9 0.25 11.1 3.6 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_S46 PF10459.4 EJS42181.1 - 0.85 7.9 12.3 1 7.7 8.5 1.1 1 0 0 1 1 1 0 Peptidase S46 FlaC_arch PF05377.6 EJS42181.1 - 1 9.3 9.1 2.5 8.0 0.2 3.5 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1395 PF07160.7 EJS42181.1 - 1 8.7 13.8 2 7.8 9.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1395) Reo_sigmaC PF04582.7 EJS42181.1 - 1.1 8.4 12.6 0.63 9.1 6.9 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Cep57_MT_bd PF06657.8 EJS42181.1 - 1.3 9.0 12.8 0.16 11.9 4.3 2.5 1 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Uds1 PF15456.1 EJS42181.1 - 1.3 8.9 11.7 2.5 8.0 8.0 1.6 1 1 0 1 1 1 0 Up-regulated During Septation Tropomyosin_1 PF12718.2 EJS42181.1 - 1.7 8.4 17.2 0.19 11.5 8.2 2.0 1 1 1 2 2 2 0 Tropomyosin like RmuC PF02646.11 EJS42181.1 - 1.7 7.3 17.7 2 7.1 1.8 2.2 1 1 0 2 2 2 0 RmuC family Sec34 PF04136.10 EJS42181.1 - 1.9 8.1 15.1 2.1 8.0 5.8 2.2 1 1 1 2 2 2 0 Sec34-like family BLOC1_2 PF10046.4 EJS42181.1 - 2 8.6 21.9 2.6 8.2 4.3 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.3 EJS42181.1 - 3.2 6.9 24.0 0.55 9.4 9.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF972 PF06156.8 EJS42181.1 - 3.8 7.8 17.8 4.9 7.5 7.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Striatin PF08232.7 EJS42181.1 - 3.9 7.7 14.5 8.6 6.6 10.0 1.7 1 1 0 1 1 1 0 Striatin family DUF4200 PF13863.1 EJS42181.1 - 4.5 7.2 18.1 0.74 9.7 8.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CDC37_N PF03234.9 EJS42181.1 - 4.5 7.5 15.2 6.4 7.0 10.6 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1664 PF07889.7 EJS42181.1 - 6.7 6.5 12.6 0.67 9.7 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DHBP_synthase PF00926.14 EJS42182.1 - 3.2e-79 264.6 0.1 3.6e-79 264.5 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase WD40 PF00400.27 EJS42183.1 - 1.6e-06 27.7 0.0 8.5e-05 22.2 0.0 2.8 2 1 1 3 3 3 1 WD domain, G-beta repeat Sld5 PF05916.6 EJS42184.1 - 6.5e-14 52.1 0.4 1.7e-13 50.7 0.3 1.8 1 0 0 1 1 1 1 GINS complex protein DUF1968 PF09291.5 EJS42184.1 - 0.045 13.5 1.0 0.11 12.3 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1968) Pkinase PF00069.20 EJS42185.1 - 4.5e-62 209.5 0.0 7.3e-62 208.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42185.1 - 5.9e-30 104.1 0.0 9.7e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS42185.1 - 1.6e-07 30.5 0.0 1.4e-06 27.5 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EJS42185.1 - 0.0086 15.1 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS42185.1 - 0.04 13.6 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FliD_N PF02465.13 EJS42185.1 - 0.093 13.1 2.1 0.28 11.5 1.5 1.8 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus HlyIII PF03006.15 EJS42186.1 - 4.8e-55 186.3 25.5 5.7e-55 186.1 17.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Complex1_LYR PF05347.10 EJS42187.1 - 0.066 13.0 0.1 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Complex 1 protein (LYR family) CPL PF08144.6 EJS42189.1 - 5.9e-17 61.8 0.0 5.4e-15 55.5 0.0 3.1 2 0 0 2 2 2 1 CPL (NUC119) domain PUF PF00806.14 EJS42189.1 - 5.4e-06 25.5 5.7 0.11 12.0 0.0 6.3 7 0 0 7 7 7 1 Pumilio-family RNA binding repeat DUF4253 PF14062.1 EJS42189.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) Tubulin-binding PF00418.14 EJS42189.1 - 0.13 11.9 0.4 0.49 10.1 0.3 2.0 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat Daxx PF03344.10 EJS42189.1 - 1.3 7.3 19.2 1.9 6.8 13.3 1.1 1 0 0 1 1 1 0 Daxx Family Sugar_tr PF00083.19 EJS42190.1 - 4.5e-147 490.2 33.4 5.3e-147 490.0 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS42190.1 - 1.3e-30 106.2 34.5 1.9e-29 102.5 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EJS42190.1 - 2.3e-05 22.7 1.2 2.3e-05 22.7 0.8 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector Lig_chan PF00060.21 EJS42190.1 - 0.29 10.8 8.9 1.5 8.5 0.1 3.7 3 1 0 3 3 3 0 Ligand-gated ion channel Sec20 PF03908.8 EJS42191.1 - 4e-34 116.1 0.5 9e-34 115.0 0.4 1.6 1 0 0 1 1 1 1 Sec20 FHA PF00498.21 EJS42192.1 - 3.3e-06 27.1 0.0 1.3e-05 25.2 0.0 2.1 1 0 0 1 1 1 1 FHA domain S-AdoMet_synt_C PF02773.11 EJS42193.1 - 1.1e-74 248.6 0.2 1.8e-74 247.9 0.2 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EJS42193.1 - 7.8e-47 158.1 0.0 1.5e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EJS42193.1 - 9.2e-45 150.9 0.1 1.9e-44 149.9 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain PAP2 PF01569.16 EJS42194.1 - 2.1e-21 75.9 1.9 4.5e-21 74.8 0.8 1.9 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EJS42194.1 - 8.3e-05 22.1 0.6 8.3e-05 22.1 0.4 2.1 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.1 EJS42194.1 - 0.006 16.8 4.2 0.006 16.8 2.9 2.6 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PSP1 PF04468.7 EJS42195.1 - 9.1e-38 128.1 0.2 2.6e-37 126.6 0.1 1.9 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Sugar_tr PF00083.19 EJS42196.1 - 1.5e-89 300.6 31.7 9.2e-51 172.8 4.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EJS42196.1 - 9.2e-24 83.7 31.9 2.8e-19 69.0 7.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 EJS42196.1 - 9.9 6.3 9.5 1.8 8.6 2.2 2.9 4 0 0 4 4 4 0 Phage holin family 2 BAR PF03114.13 EJS42197.1 - 1.4e-63 214.5 7.6 1.7e-63 214.2 5.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EJS42197.1 - 8.7e-15 53.8 0.0 1.4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EJS42197.1 - 1.6e-13 50.0 0.1 2.6e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EJS42197.1 - 1.6e-08 33.8 0.0 2.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EJS42197.1 - 0.39 9.9 6.6 0.19 10.9 0.2 2.1 2 0 0 2 2 2 0 Vps5 C terminal like Spectrin PF00435.16 EJS42197.1 - 0.96 9.7 6.3 5.9 7.2 0.8 2.4 2 0 0 2 2 2 0 Spectrin repeat DUF755 PF05501.6 EJS42197.1 - 1.5 8.9 7.9 0.13 12.3 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) RhoGAP PF00620.22 EJS42198.1 - 2.2e-31 108.5 0.6 2.5e-30 105.0 0.1 2.7 2 1 0 2 2 2 1 RhoGAP domain DUF3408 PF11888.3 EJS42198.1 - 0.58 10.0 11.1 1.7 8.5 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3408) ThiF PF00899.16 EJS42199.1 - 1.5e-35 121.9 0.0 2.9e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EJS42199.1 - 9.6e-26 89.1 3.2 2.2e-25 88.0 0.5 2.6 3 0 0 3 3 3 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EJS42199.1 - 2.3e-21 74.9 3.8 4.8e-21 73.8 2.7 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EJS42199.1 - 4.8e-05 23.3 0.3 0.00012 22.0 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 EJS42199.1 - 0.0083 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EJS42199.1 - 0.011 15.9 0.0 0.099 12.9 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Utp13 PF08625.6 EJS42199.1 - 0.013 15.0 1.0 0.03 13.9 0.7 1.6 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Aida_N PF08910.5 EJS42199.1 - 0.032 14.4 0.1 0.11 12.7 0.1 1.9 1 0 0 1 1 1 0 Aida N-terminus TGT PF01702.13 EJS42199.1 - 0.063 12.5 1.2 0.1 11.8 0.2 1.7 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase Polysacc_synt_2 PF02719.10 EJS42199.1 - 0.064 12.1 0.1 0.36 9.6 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF3232 PF11554.3 EJS42199.1 - 0.088 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) Hormone_2 PF00123.15 EJS42199.1 - 0.11 12.4 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Peptide hormone TFIID-18kDa PF02269.11 EJS42200.1 - 4.6e-38 128.9 0.5 5.1e-37 125.5 0.1 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Synaptobrevin PF00957.16 EJS42200.1 - 0.15 11.7 4.6 0.052 13.1 1.0 1.9 2 0 0 2 2 2 0 Synaptobrevin She9_MDM33 PF05546.6 EJS42201.1 - 2.1e-95 318.1 14.7 2.1e-95 318.1 10.2 2.1 2 0 0 2 2 2 2 She9 / Mdm33 family PsbH PF00737.15 EJS42201.1 - 0.067 12.7 0.5 0.14 11.7 0.4 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein AAA PF00004.24 EJS42202.1 - 1.7e-46 157.6 0.1 7.6e-46 155.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EJS42202.1 - 3.6e-08 33.4 0.0 7.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EJS42202.1 - 1e-07 31.7 0.1 4.3e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EJS42202.1 - 5e-07 29.8 0.1 1.7e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EJS42202.1 - 2.8e-06 27.5 2.0 9.2e-05 22.5 0.3 2.8 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 EJS42202.1 - 9.8e-05 21.3 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EJS42202.1 - 0.00021 21.2 0.0 0.00054 19.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 EJS42202.1 - 0.00038 20.2 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 NTPase RuvB_N PF05496.7 EJS42202.1 - 0.0005 19.1 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EJS42202.1 - 0.00054 20.7 0.1 0.0022 18.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 EJS42202.1 - 0.0011 18.5 0.0 0.009 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EJS42202.1 - 0.0015 18.2 0.1 0.0037 16.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 EJS42202.1 - 0.0018 17.9 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EJS42202.1 - 0.0019 17.3 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EJS42202.1 - 0.002 18.3 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 EJS42202.1 - 0.0024 17.7 0.0 0.006 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EJS42202.1 - 0.0026 17.4 0.2 0.044 13.4 0.0 2.5 1 1 0 2 2 2 1 NACHT domain AAA_30 PF13604.1 EJS42202.1 - 0.003 17.1 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EJS42202.1 - 0.0036 16.9 0.0 0.0098 15.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EJS42202.1 - 0.0037 16.0 0.0 0.0059 15.3 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EJS42202.1 - 0.004 16.5 1.0 0.13 11.6 0.1 2.5 1 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EJS42202.1 - 0.0042 16.5 0.0 0.14 11.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EJS42202.1 - 0.005 16.8 0.1 0.012 15.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain UPF0079 PF02367.12 EJS42202.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EJS42202.1 - 0.006 15.7 0.1 0.016 14.4 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EJS42202.1 - 0.0071 16.6 0.0 0.045 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EJS42202.1 - 0.0081 15.8 0.6 0.094 12.3 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 EJS42202.1 - 0.013 14.8 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 EJS42202.1 - 0.023 15.0 3.2 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EJS42202.1 - 0.061 12.1 0.3 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.22 EJS42202.1 - 0.1 12.9 0.1 0.34 11.2 0.0 2.2 2 1 0 2 2 2 0 ABC transporter IBN_N PF03810.14 EJS42203.1 - 5.5e-20 71.0 0.1 2.2e-19 69.1 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.5 EJS42203.1 - 1.3e-06 27.2 0.5 1.3e-06 27.2 0.4 3.5 3 2 1 4 4 4 1 Cse1 Vac14_Fab1_bd PF12755.2 EJS42203.1 - 0.64 10.4 3.4 1.5 9.2 0.0 3.4 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Utp12 PF04003.7 EJS42204.1 - 9.5e-23 80.2 0.5 1.7e-22 79.4 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family C2 PF00168.25 EJS42204.1 - 0.043 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 C2 domain p450 PF00067.17 EJS42205.1 - 5.2e-54 183.4 0.0 6.7e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.7 EJS42206.1 - 1.2e-104 349.5 0.0 1.5e-104 349.2 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein BssC_TutF PF08201.6 EJS42206.1 - 0.018 14.5 0.4 0.05 13.0 0.2 1.7 1 0 0 1 1 1 0 BssC/TutF protein SHS2_Rpb7-N PF03876.12 EJS42207.1 - 1.4e-16 60.3 0.0 2.8e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EJS42207.1 - 1.2e-15 57.3 0.1 1.8e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EJS42207.1 - 1.7e-06 28.1 0.0 3.4e-06 27.2 0.0 1.4 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 Ribosomal_L23 PF00276.15 EJS42208.1 - 2.9e-26 91.2 0.0 4.5e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 ABC2_membrane PF01061.19 EJS42209.1 - 1.5e-91 305.2 53.5 3e-46 157.2 17.4 2.4 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EJS42209.1 - 8.2e-42 141.0 3.5 1.1e-38 131.0 0.2 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EJS42209.1 - 4.4e-38 130.6 0.0 7.9e-18 65.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_trans_N PF14510.1 EJS42209.1 - 5.8e-22 77.5 8.5 2.8e-21 75.4 5.9 2.2 1 1 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EJS42209.1 - 4.3e-08 32.7 0.0 0.00018 20.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EJS42209.1 - 6.7e-07 28.6 30.6 2e-05 23.7 6.1 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 EJS42209.1 - 3.3e-06 27.1 0.1 0.00022 21.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EJS42209.1 - 2.5e-05 23.8 0.5 0.044 13.2 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EJS42209.1 - 3.2e-05 24.2 0.4 0.035 14.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EJS42209.1 - 0.0001 22.2 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EJS42209.1 - 0.00017 21.2 0.1 0.32 10.7 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_29 PF13555.1 EJS42209.1 - 0.00036 19.9 0.4 0.005 16.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EJS42209.1 - 0.00047 19.3 0.0 0.0071 15.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EJS42209.1 - 0.001 19.2 0.3 0.54 10.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 EJS42209.1 - 0.0013 18.7 0.0 0.015 15.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EJS42209.1 - 0.0019 17.4 0.2 0.064 12.4 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EJS42209.1 - 0.0022 17.6 0.3 2.6 7.6 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 EJS42209.1 - 0.0028 18.4 0.0 1.4 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EJS42209.1 - 0.0039 17.1 0.8 0.13 12.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EJS42209.1 - 0.02 14.5 0.2 0.9 9.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EJS42209.1 - 0.025 14.2 0.0 2 8.0 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EJS42209.1 - 0.066 13.4 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EJS42209.1 - 0.089 12.2 0.4 2.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EJS42209.1 - 0.091 13.0 0.0 0.091 13.0 0.0 3.0 4 0 0 4 4 3 0 AAA domain TRAPPC9-Trs120 PF08626.6 EJS42210.1 - 0 1339.0 45.6 0 1338.0 31.6 1.5 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Formyl_trans_N PF00551.14 EJS42211.1 - 1.5e-58 197.3 0.1 1.8e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Glyco_trans_4_4 PF13579.1 EJS42211.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain PINIT PF14324.1 EJS42212.1 - 2.6e-38 131.3 0.1 1.4e-36 125.6 0.0 2.6 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.15 EJS42212.1 - 3.4e-21 74.4 7.3 7.2e-21 73.4 5.0 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EJS42212.1 - 2.1e-10 39.8 0.0 3.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 EJS42212.1 - 0.00037 19.9 1.5 0.00093 18.6 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EJS42212.1 - 0.03 14.0 3.3 0.086 12.5 2.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EJS42212.1 - 0.94 9.5 4.0 1.8 8.6 2.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EJS42212.1 - 1.9 8.4 3.9 3.6 7.5 2.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Nop25 PF09805.4 EJS42213.1 - 1.4e-38 132.0 19.1 1.4e-38 132.0 13.3 2.0 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) EXS PF03124.9 EJS42214.1 - 3.1e-62 210.6 30.0 3.6e-62 210.3 20.8 1.0 1 0 0 1 1 1 1 EXS family Peptidase_M28 PF04389.12 EJS42215.1 - 4.8e-26 91.5 0.0 7.9e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EJS42215.1 - 9.6e-06 25.2 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Pox_E6 PF04656.7 EJS42215.1 - 0.021 13.0 0.4 0.031 12.4 0.3 1.2 1 0 0 1 1 1 0 Pox virus E6 protein Ribosomal_L11_N PF03946.9 EJS42216.1 - 4.3e-17 61.3 0.2 8.6e-17 60.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EJS42216.1 - 3.1e-11 43.2 1.1 5.3e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain IMS PF00817.15 EJS42217.1 - 3.5e-46 156.6 0.0 5.8e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EJS42217.1 - 1.8e-12 47.3 0.6 4.5e-12 45.9 0.0 2.0 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EJS42217.1 - 0.00079 19.3 0.1 0.0019 18.1 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif DUF1805 PF08827.6 EJS42217.1 - 0.025 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Sugar_tr PF00083.19 EJS42218.1 - 6.1e-175 582.1 38.4 6.9e-175 581.9 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS42218.1 - 4.5e-31 107.8 35.2 3.1e-28 98.4 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.1 EJS42218.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Svf1 PF08622.5 EJS42219.1 - 1.3e-140 468.0 3.2 1.8e-140 467.5 2.2 1.2 1 0 0 1 1 1 1 Svf1-like Nop14 PF04147.7 EJS42219.1 - 0.091 10.6 22.3 0.02 12.8 1.4 2.1 2 0 0 2 2 2 0 Nop14-like family CobT PF06213.7 EJS42219.1 - 0.67 9.0 25.9 0.069 12.2 3.5 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF3449 PF11931.3 EJS42219.1 - 1.1 8.6 9.4 3.7 7.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) BUD22 PF09073.5 EJS42219.1 - 1.5 7.7 24.8 0.12 11.3 4.5 2.1 2 0 0 2 2 2 0 BUD22 TRAP_alpha PF03896.11 EJS42219.1 - 3.6 6.4 18.2 1.2 8.0 1.1 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Prothymosin PF03247.9 EJS42219.1 - 7.4 6.7 43.7 2.5 8.3 13.8 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family Sod_Fe_C PF02777.13 EJS42220.1 - 1.1e-11 44.5 0.3 4.1e-05 23.3 0.0 2.5 1 1 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Pal1 PF08316.6 EJS42221.1 - 8.3e-58 194.8 3.3 8.3e-58 194.8 2.3 2.9 3 1 0 3 3 3 1 Pal1 cell morphology protein R3H PF01424.17 EJS42221.1 - 0.016 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 R3H domain Asp PF00026.18 EJS42222.1 - 8.2e-22 77.8 1.1 3.1e-21 75.9 0.8 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EJS42222.1 - 0.025 14.1 0.3 0.058 12.9 0.0 1.7 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal PQ-loop PF04193.9 EJS42224.1 - 1.5e-36 123.7 10.7 1.7e-18 65.8 0.6 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EJS42224.1 - 0.028 14.2 6.0 0.29 11.0 0.2 3.5 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange Pyr_redox_2 PF07992.9 EJS42225.1 - 1.7e-28 99.9 0.1 2e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EJS42225.1 - 9.7e-18 64.3 0.2 1.1e-14 54.5 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EJS42225.1 - 2.5e-09 37.4 0.0 6.5e-07 29.6 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EJS42225.1 - 3.3e-06 26.2 0.4 0.44 9.3 0.1 4.0 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EJS42225.1 - 0.00025 21.2 0.0 0.068 13.4 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EJS42225.1 - 0.00029 20.8 0.0 0.019 14.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EJS42225.1 - 0.0011 18.1 0.2 0.0092 15.0 0.0 2.3 2 1 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EJS42225.1 - 0.0012 17.7 0.5 0.57 8.9 0.1 2.6 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 EJS42225.1 - 0.0015 17.5 0.1 2 7.2 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EJS42225.1 - 0.0018 18.3 0.2 0.75 9.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 EJS42225.1 - 0.013 14.3 0.1 1.2 8.0 0.0 3.2 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EJS42225.1 - 0.015 14.4 0.1 4.1 6.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EJS42225.1 - 0.027 14.1 0.1 7.9 6.1 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 EJS42225.1 - 0.036 12.5 0.2 1.8 6.9 0.1 2.6 2 1 1 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.1 EJS42225.1 - 0.095 12.4 0.0 5.8 6.6 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glycos_transf_3 PF00591.16 EJS42226.1 - 2.3e-86 289.2 0.0 3e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EJS42226.1 - 2.7e-17 62.0 0.0 6e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Filament PF00038.16 EJS42227.1 - 3.9e-05 23.2 59.4 3.9e-05 23.2 41.2 5.2 1 1 4 5 5 5 3 Intermediate filament protein Spc7 PF08317.6 EJS42227.1 - 0.0021 16.8 26.9 0.0021 16.8 18.7 6.1 1 1 4 6 6 6 3 Spc7 kinetochore protein Surfac_D-trimer PF09006.6 EJS42227.1 - 0.11 12.2 0.8 1.9 8.2 0.0 3.5 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation DUF3584 PF12128.3 EJS42227.1 - 0.33 8.2 129.1 0.14 9.5 28.8 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) HrpB7 PF09486.5 EJS42227.1 - 5 7.0 50.4 0.021 14.7 9.8 5.6 2 2 3 5 5 5 0 Bacterial type III secretion protein (HrpB7) Reo_sigmaC PF04582.7 EJS42227.1 - 9.6 5.2 55.1 0.57 9.3 4.6 6.0 1 1 6 7 7 7 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EJS42227.1 - 9.9 5.9 158.6 0.33 10.7 21.1 7.7 1 1 5 6 6 6 0 TPR/MLP1/MLP2-like protein VHS PF00790.14 EJS42228.1 - 1.1e-48 164.4 0.0 3.3e-48 162.9 0.0 1.8 1 0 0 1 1 1 1 VHS domain Alpha_adaptinC2 PF02883.15 EJS42228.1 - 2.9e-16 59.8 0.2 6.2e-16 58.7 0.2 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 EJS42228.1 - 7.7e-13 48.2 3.6 7.7e-13 48.2 2.5 3.0 3 0 0 3 3 3 1 GAT domain DUF3620 PF12281.3 EJS42228.1 - 1.1 8.8 3.8 1 8.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3620) BCIP PF13862.1 EJS42229.1 - 2.7e-51 173.8 1.4 2.7e-51 173.8 0.9 1.4 2 0 0 2 2 2 1 p21-C-terminal region-binding protein YL1 PF05764.8 EJS42230.1 - 0.04 13.5 7.9 0.06 12.9 5.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein WD40 PF00400.27 EJS42230.1 - 0.51 10.3 6.0 21 5.2 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat DSS1_SEM1 PF05160.8 EJS42231.1 - 1.9e-21 75.5 14.3 2.5e-21 75.1 9.9 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.7 EJS42231.1 - 0.23 11.1 8.1 0.28 10.8 5.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.27 EJS42232.1 - 7.6e-36 120.7 11.5 4.3e-10 39.0 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat FRG1 PF06229.7 EJS42232.1 - 0.024 14.0 1.6 0.066 12.6 1.1 1.7 1 0 0 1 1 1 0 FRG1-like family Rav1p_C PF12234.3 EJS42232.1 - 0.1 10.7 0.0 0.93 7.5 0.0 2.0 2 0 0 2 2 2 0 RAVE protein 1 C terminal NUC153 PF08159.7 EJS42233.1 - 4.8e-15 54.8 10.3 1.5e-14 53.2 1.3 3.2 3 0 0 3 3 3 2 NUC153 domain Aldo_ket_red PF00248.16 EJS42234.1 - 2.2e-52 177.6 0.0 2.7e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SpoU_sub_bind PF08032.7 EJS42234.1 - 0.0063 16.6 0.1 0.11 12.6 0.0 2.8 3 0 0 3 3 3 1 RNA 2'-O ribose methyltransferase substrate binding GPP34 PF05719.6 EJS42235.1 - 3.3e-60 203.6 0.0 4.1e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) EF-hand_7 PF13499.1 EJS42236.1 - 5.3e-27 93.7 17.8 1.6e-13 50.5 1.0 3.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EJS42236.1 - 8.1e-26 87.3 5.5 1.3e-07 30.3 0.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EJS42236.1 - 1.6e-23 80.3 2.8 2.1e-06 27.1 0.1 4.7 5 0 0 5 5 4 3 EF-hand domain EF-hand_5 PF13202.1 EJS42236.1 - 3.2e-17 61.0 3.3 1.1e-05 24.5 0.2 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EJS42236.1 - 2.5e-16 59.0 7.7 7.2e-08 31.9 0.6 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EJS42236.1 - 3.1e-05 23.6 3.4 0.52 10.0 0.0 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EJS42236.1 - 3.4e-05 23.8 0.7 0.00085 19.3 0.3 2.8 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EJS42236.1 - 8.1e-05 22.4 0.1 0.0081 16.0 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain AAA_34 PF13872.1 EJS42236.1 - 0.014 14.1 0.0 0.98 8.1 0.0 2.2 1 1 1 2 2 2 0 P-loop containing NTP hydrolase pore-1 S10_plectin PF03501.10 EJS42236.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_10 PF14788.1 EJS42236.1 - 0.023 14.3 0.2 4.4 7.0 0.0 3.1 4 0 0 4 4 4 0 EF hand PHB_acc_N PF07879.6 EJS42236.1 - 0.087 12.5 0.2 5.7 6.7 0.1 2.6 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain YTH PF04146.10 EJS42237.1 - 6.8e-42 142.3 0.6 1.2e-41 141.6 0.4 1.4 1 0 0 1 1 1 1 YT521-B-like domain EVE PF01878.13 EJS42237.1 - 0.023 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 EVE domain BCS1_N PF08740.6 EJS42239.1 - 3.1e-51 173.6 0.1 4.9e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EJS42239.1 - 2.1e-23 82.9 0.0 3.7e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EJS42239.1 - 7e-06 26.8 0.0 1.4e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EJS42239.1 - 0.00047 20.2 0.1 0.0008 19.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EJS42239.1 - 0.00054 19.8 0.0 0.0014 18.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EJS42239.1 - 0.00068 19.9 0.0 0.003 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EJS42239.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EJS42239.1 - 0.0018 18.4 0.0 0.0056 16.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 EJS42239.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EJS42239.1 - 0.0024 17.9 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EJS42239.1 - 0.0035 17.0 0.0 0.011 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EJS42239.1 - 0.0047 16.8 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EJS42239.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EJS42239.1 - 0.0075 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 EJS42239.1 - 0.0099 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 EJS42239.1 - 0.013 15.1 0.0 0.28 10.8 0.0 2.5 2 1 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 EJS42239.1 - 0.014 14.9 0.0 0.06 12.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EJS42239.1 - 0.023 14.2 0.1 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EJS42239.1 - 0.027 14.1 0.0 0.071 12.8 0.0 1.7 2 0 0 2 2 1 0 Archaeal ATPase KaiC PF06745.8 EJS42239.1 - 0.028 13.5 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 EJS42239.1 - 0.029 14.5 0.0 0.074 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EJS42239.1 - 0.045 13.5 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 EJS42239.1 - 0.065 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 EJS42239.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EJS42239.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EJS42239.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3315 PF11776.3 EJS42239.1 - 0.33 10.4 1.7 0.34 10.4 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF3315) F1F0-ATPsyn_F PF10791.4 EJS42240.1 - 3.5e-43 145.7 0.3 3.9e-43 145.6 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EJS42240.1 - 0.0014 18.6 0.1 0.0021 18.0 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f RhoGAP PF00620.22 EJS42241.1 - 2.9e-45 153.6 0.6 6.1e-45 152.5 0.4 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EJS42241.1 - 1.4e-14 53.9 30.0 3e-09 36.8 5.4 2.6 2 0 0 2 2 2 2 LIM domain Complex1_LYR PF05347.10 EJS42242.1 - 1.7e-11 43.7 0.1 2.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EJS42242.1 - 1e-09 38.4 0.0 1.2e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Topoisom_I_N PF02919.10 EJS42242.1 - 0.048 12.9 0.0 0.053 12.7 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment TPP_enzyme_N PF02776.13 EJS42243.1 - 1.2e-27 96.4 0.0 2e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EJS42243.1 - 2.3e-20 72.7 0.0 4.1e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EJS42243.1 - 3.9e-16 58.9 0.0 9.4e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ribosomal_60s PF00428.14 EJS42244.1 - 8.4e-23 80.5 15.0 1.1e-22 80.2 10.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein WXG100 PF06013.7 EJS42245.1 - 0.097 12.6 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Grp1_Fun34_YaaH PF01184.14 EJS42246.1 - 1.1e-63 214.3 13.1 1.4e-63 214.0 9.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ApbA_C PF08546.6 EJS42247.1 - 0.00026 20.9 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAC PF01849.13 EJS42248.1 - 8.4e-15 54.0 0.0 1.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 NAC domain CENP-N PF05238.8 EJS42249.1 - 4e-107 358.7 0.0 4.6e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like zf-RING_UBOX PF13445.1 EJS42250.1 - 9.6e-16 57.2 0.6 5.2e-15 54.8 0.4 2.4 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 EJS42250.1 - 5.5e-09 35.8 0.2 5.5e-09 35.8 0.1 2.8 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 EJS42250.1 - 0.0052 16.5 0.5 0.014 15.1 0.3 1.8 1 0 0 1 1 1 1 Ring finger domain DUF3671 PF12420.3 EJS42250.1 - 0.018 15.0 0.6 0.018 15.0 0.4 2.7 3 1 1 4 4 3 0 Protein of unknown function DUF3631 PF12307.3 EJS42250.1 - 0.023 14.6 0.6 0.72 9.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) zf-RING_5 PF14634.1 EJS42250.1 - 0.068 12.9 0.6 0.24 11.1 0.4 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Exonuc_VII_L PF02601.10 EJS42250.1 - 0.076 12.2 6.0 0.095 11.8 4.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Caps_synth_GfcC PF06251.6 EJS42250.1 - 0.22 10.6 3.2 0.24 10.5 1.0 1.8 2 0 0 2 2 2 0 Capsule biosynthesis GfcC PAP_central PF04928.12 EJS42250.1 - 0.27 10.0 4.8 0.58 8.9 3.2 1.6 1 1 0 1 1 1 0 Poly(A) polymerase central domain HrcA PF01628.16 EJS42250.1 - 0.28 10.7 3.5 14 5.2 0.0 2.2 2 0 0 2 2 2 0 HrcA protein C terminal domain MRP-L51 PF10244.4 EJS42250.1 - 0.94 9.5 7.3 0.9 9.6 3.6 2.0 2 1 0 2 2 2 0 Mitochondrial ribosomal subunit Tmemb_9 PF05434.6 EJS42250.1 - 1.2 8.8 9.9 0.25 11.0 4.3 1.7 2 0 0 2 2 2 0 TMEM9 SET PF00856.23 EJS42251.1 - 1.4e-09 38.4 0.1 1.5e-08 35.1 0.0 2.3 1 1 0 1 1 1 1 SET domain Usher PF00577.15 EJS42251.1 - 0.11 11.1 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Outer membrane usher protein AAA_2 PF07724.9 EJS42252.1 - 3.6e-51 173.4 0.1 7.4e-49 165.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EJS42252.1 - 3.3e-25 87.7 0.6 1.2e-24 86.0 0.4 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EJS42252.1 - 6.1e-22 78.2 0.1 3.3e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EJS42252.1 - 2e-15 56.7 0.2 7.3e-11 41.9 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EJS42252.1 - 4e-15 56.2 3.0 0.00011 22.2 0.0 4.8 3 2 2 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 EJS42252.1 - 6.1e-09 36.1 0.0 0.0035 17.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EJS42252.1 - 7.6e-08 32.3 0.0 0.021 14.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EJS42252.1 - 2.5e-07 30.6 6.3 0.055 13.1 0.0 4.4 3 2 0 4 4 3 2 Archaeal ATPase IstB_IS21 PF01695.12 EJS42252.1 - 5.1e-07 29.2 0.0 0.048 13.0 0.0 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 EJS42252.1 - 8.1e-07 29.8 5.5 0.015 16.1 0.0 4.1 4 1 0 4 4 3 2 AAA domain Sigma54_activat PF00158.21 EJS42252.1 - 8.2e-07 28.6 0.1 2.7e-05 23.7 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 EJS42252.1 - 7.5e-05 23.0 7.1 0.083 13.1 0.0 3.7 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 EJS42252.1 - 8.8e-05 22.2 0.0 0.1 12.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 EJS42252.1 - 0.00015 21.7 0.1 0.018 14.9 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EJS42252.1 - 0.00019 20.6 0.0 0.0026 16.8 0.0 2.7 2 1 0 2 2 2 1 Zeta toxin ABC_tran PF00005.22 EJS42252.1 - 0.00021 21.6 0.2 0.1 12.8 0.0 3.0 3 0 0 3 3 2 1 ABC transporter MobB PF03205.9 EJS42252.1 - 0.00073 19.2 0.0 0.38 10.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EJS42252.1 - 0.00082 19.0 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 EJS42252.1 - 0.00096 19.1 0.0 0.45 10.4 0.0 3.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EJS42252.1 - 0.001 19.2 0.0 1.5 9.0 0.0 3.1 2 0 0 2 2 2 1 RNA helicase T2SE PF00437.15 EJS42252.1 - 0.0011 17.8 0.6 0.029 13.2 0.1 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 EJS42252.1 - 0.0015 18.0 0.0 0.29 10.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EJS42252.1 - 0.0018 17.4 0.0 0.39 9.8 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_30 PF13604.1 EJS42252.1 - 0.0026 17.3 0.0 1.1 8.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EJS42252.1 - 0.0027 17.1 0.0 0.49 9.8 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 EJS42252.1 - 0.0028 17.5 0.1 4.6 7.0 0.0 3.5 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EJS42252.1 - 0.0034 16.8 2.0 1.1 8.6 0.0 3.4 3 1 0 3 3 3 1 AAA domain UPF0079 PF02367.12 EJS42252.1 - 0.007 15.9 0.0 1.5 8.4 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 EJS42252.1 - 0.011 15.1 0.0 1.7 8.0 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Torsin PF06309.6 EJS42252.1 - 0.012 15.5 0.0 0.075 12.9 0.0 2.2 2 0 0 2 2 2 0 Torsin TrwB_AAD_bind PF10412.4 EJS42252.1 - 0.013 14.1 0.0 1.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 EJS42252.1 - 0.014 15.2 0.2 1.1 9.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_21 PF13304.1 EJS42252.1 - 0.017 15.0 4.4 3.3 7.5 0.0 4.1 3 1 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 EJS42252.1 - 0.018 14.2 0.0 1.2 8.2 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI LacI PF00356.16 EJS42252.1 - 0.033 13.8 0.0 4 7.1 0.0 2.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family PhoH PF02562.11 EJS42252.1 - 0.035 13.3 0.0 2.8 7.1 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 EJS42252.1 - 0.059 12.9 0.1 1.3 8.5 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EJS42252.1 - 0.075 12.9 0.1 4.3 7.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_6 PF12774.2 EJS42252.1 - 0.18 11.3 0.2 14 5.1 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region D1 DUF1090 PF06476.7 EJS42252.1 - 1.8 8.2 11.6 0.75 9.4 0.8 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1090) Apc13p PF05839.6 EJS42253.1 - 8.4e-28 96.1 0.2 1.4e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 Apc13p protein CKS PF01111.14 EJS42253.1 - 0.12 12.1 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit Pex2_Pex12 PF04757.9 EJS42254.1 - 5e-35 120.9 3.4 7.3e-35 120.4 2.4 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EJS42254.1 - 4.8e-09 35.9 16.9 8.5e-09 35.1 11.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EJS42254.1 - 2.5e-08 33.8 17.5 4.8e-08 32.8 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EJS42254.1 - 5e-07 29.2 17.0 8e-07 28.6 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EJS42254.1 - 3.1e-06 26.7 16.1 6.1e-06 25.7 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EJS42254.1 - 2.9e-05 23.6 13.0 5.7e-05 22.7 9.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EJS42254.1 - 0.0013 18.8 9.3 0.0031 17.5 6.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EJS42254.1 - 0.014 15.1 6.3 0.014 15.1 4.4 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EJS42254.1 - 0.016 15.0 17.0 0.034 14.0 11.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EJS42255.1 - 7.6e-07 28.7 8.9 7.6e-07 28.7 6.1 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) tRNA-synt_1b PF00579.20 EJS42256.1 - 2.7e-83 279.4 0.0 3.4e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Lactamase_B PF00753.22 EJS42257.1 - 1.4e-24 86.8 0.0 1.9e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EJS42257.1 - 1.4e-07 31.2 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EJS42257.1 - 0.0034 17.1 0.1 0.0048 16.6 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Gp-FAR-1 PF05823.7 EJS42257.1 - 0.028 14.3 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) S_100 PF01023.14 EJS42257.1 - 0.11 11.8 0.3 0.21 10.9 0.2 1.4 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Pmp3 PF01679.12 EJS42258.1 - 2e-20 72.2 6.0 2.2e-20 72.0 4.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BTP PF05232.7 EJS42258.1 - 0.33 10.7 2.2 0.4 10.4 1.5 1.1 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family DUF915 PF06028.6 EJS42259.1 - 0.023 13.7 0.6 0.042 12.9 0.4 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Tir_receptor_C PF07489.6 EJS42259.1 - 0.32 10.7 5.0 0.55 9.9 3.5 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus RNase_H2-Ydr279 PF09468.5 EJS42260.1 - 5.8e-50 170.2 1.6 6.9e-50 169.9 1.1 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) HGTP_anticodon2 PF12745.2 EJS42261.1 - 6.9e-99 330.4 5.7 6.9e-99 330.4 3.9 2.7 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EJS42261.1 - 5e-71 238.9 13.0 3.5e-45 154.1 0.1 4.6 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42261.1 - 2.3e-41 141.6 0.2 1e-25 90.3 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 EJS42261.1 - 1.6e-15 56.9 0.0 5.4e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 EJS42261.1 - 3e-15 56.0 2.5 1.2e-14 54.0 1.7 2.2 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.1 EJS42261.1 - 0.0031 16.5 0.0 0.17 10.7 0.0 2.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EJS42261.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HrpB7 PF09486.5 EJS42262.1 - 0.012 15.5 0.2 0.012 15.5 0.1 5.4 4 1 2 6 6 6 0 Bacterial type III secretion protein (HrpB7) Herpes_ICP4_N PF03584.10 EJS42262.1 - 0.13 11.7 2.4 4.6 6.7 0.3 3.0 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region DUF2968 PF11180.3 EJS42262.1 - 4.7 6.5 57.0 0.035 13.4 2.7 6.4 3 2 3 6 6 6 0 Protein of unknown function (DUF2968) Reo_sigmaC PF04582.7 EJS42262.1 - 6.6 5.8 41.7 0.24 10.5 1.9 5.3 2 2 3 6 6 6 0 Reovirus sigma C capsid protein Inositol_P PF00459.20 EJS42263.1 - 1.9e-69 234.0 0.0 2.1e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MAGE PF01454.14 EJS42264.1 - 2.5e-41 141.1 0.2 3.3e-41 140.7 0.2 1.1 1 0 0 1 1 1 1 MAGE family DUF387 PF04079.11 EJS42264.1 - 0.031 13.6 0.3 0.47 9.7 0.1 2.4 2 0 0 2 2 2 0 Putative transcriptional regulators (Ypuh-like) SRX PF09201.5 EJS42265.1 - 7.1e-66 220.4 5.5 1.4e-65 219.4 3.8 1.5 1 0 0 1 1 1 1 SRX SRP54 PF00448.17 EJS42265.1 - 5e-47 159.8 0.1 7.5e-45 152.7 0.1 2.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EJS42265.1 - 1.4e-06 28.2 0.1 5.9e-06 26.3 0.1 2.2 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EJS42265.1 - 3.3e-06 26.6 0.0 8.1e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EJS42265.1 - 0.0013 17.5 0.0 0.0034 16.1 0.0 1.8 2 1 0 2 2 2 1 ArgK protein MobB PF03205.9 EJS42265.1 - 0.0033 17.1 0.0 0.012 15.2 0.0 2.0 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EJS42265.1 - 0.0045 17.1 0.2 0.034 14.2 0.0 2.6 3 1 0 3 3 3 1 AAA domain ArsA_ATPase PF02374.10 EJS42265.1 - 0.0055 15.7 0.0 0.29 10.1 0.0 2.5 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_14 PF13173.1 EJS42265.1 - 0.018 14.9 0.1 0.63 9.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Fer4_NifH PF00142.13 EJS42265.1 - 0.022 13.9 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.1 EJS42265.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 EJS42265.1 - 1.3 8.7 9.3 0.86 9.3 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function DUF87 Pyridoxal_deC PF00282.14 EJS42266.1 - 1.7e-24 86.0 0.0 2.4e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EJS42266.1 - 2.5e-07 29.7 0.0 1.7e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EJS42266.1 - 1.3e-06 27.7 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SLA_LP_auto_ag PF05889.8 EJS42266.1 - 0.15 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) HDA2-3 PF11496.3 EJS42267.1 - 1.1e-82 277.1 8.1 1.1e-82 277.1 5.6 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 TSC22 PF01166.13 EJS42267.1 - 1 9.3 9.5 1.2 9.1 2.2 3.4 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.16 EJS42267.1 - 4.4 7.3 18.3 0.83 9.6 1.3 3.8 2 1 1 3 3 3 0 bZIP transcription factor Mhr1 PF12829.2 EJS42268.1 - 2.5e-36 123.3 3.1 4.4e-36 122.5 2.2 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination FA_hydroxylase PF04116.8 EJS42269.1 - 8e-16 58.4 9.5 8e-16 58.4 6.6 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily OSCP PF00213.13 EJS42270.1 - 4.3e-42 143.9 1.2 5e-42 143.6 0.8 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit TRAUB PF08164.7 EJS42271.1 - 6.5e-29 99.8 10.7 2e-28 98.3 0.3 3.8 3 0 0 3 3 3 2 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EJS42271.1 - 8.5e-29 100.3 4.5 8.5e-29 100.3 3.1 3.5 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor AA_kinase PF00696.23 EJS42272.1 - 2.4e-35 122.2 0.6 5e-35 121.1 0.2 1.6 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.15 EJS42272.1 - 2.3e-23 81.7 0.0 4.8e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 PUA domain CPSF_A PF03178.10 EJS42273.1 - 1.2e-83 280.9 0.4 2.9e-83 279.6 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region PIG-F PF06699.6 EJS42274.1 - 2.7e-42 144.8 22.6 1.5e-41 142.4 15.7 1.8 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Uroplakin_II PF07353.7 EJS42274.1 - 0.021 14.1 0.3 0.036 13.4 0.1 1.5 1 1 0 1 1 1 0 Uroplakin II Zn_clus PF00172.13 EJS42275.1 - 1.7e-08 34.2 6.5 3.4e-08 33.2 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 EJS42276.1 - 8.7e-43 146.2 0.4 1.1e-42 145.8 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.2 EJS42277.1 - 0.01 15.5 0.2 0.062 13.0 0.0 2.4 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EJS42277.1 - 0.05 13.2 1.8 8.6 6.1 0.0 3.9 4 0 0 4 4 4 0 F-box domain LRR_5 PF13306.1 EJS42277.1 - 0.092 12.4 9.5 0.1 12.3 0.9 3.5 1 1 1 2 2 2 0 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EJS42277.1 - 0.27 11.0 2.8 12 5.7 0.2 3.9 2 1 2 4 4 4 0 Leucine rich repeat Med21 PF11221.3 EJS42278.1 - 3.3e-50 169.8 3.6 3.7e-50 169.6 2.5 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.5 EJS42278.1 - 0.0012 18.6 0.6 0.0014 18.3 0.4 1.3 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Tropomyosin_1 PF12718.2 EJS42278.1 - 0.0026 17.5 1.1 0.0032 17.3 0.8 1.3 1 0 0 1 1 1 1 Tropomyosin like TMCO5 PF14992.1 EJS42278.1 - 0.0033 16.6 1.9 0.0046 16.1 1.3 1.2 1 0 0 1 1 1 1 TMCO5 family Med9 PF07544.8 EJS42278.1 - 0.0035 17.0 3.0 0.0043 16.7 0.2 2.2 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF4047 PF13256.1 EJS42278.1 - 0.0085 16.0 0.6 0.011 15.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4047) DUF2200 PF09966.4 EJS42278.1 - 0.075 12.8 0.6 1.3 8.8 0.0 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) DUF2972 PF11186.3 EJS42278.1 - 0.11 12.4 4.1 0.18 11.7 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) SlyX PF04102.7 EJS42278.1 - 2.4 8.6 7.2 35 4.8 2.3 3.2 2 1 0 2 2 2 0 SlyX FYVE PF01363.16 EJS42280.1 - 6.2e-20 70.8 14.2 6.2e-20 70.8 9.8 3.4 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.1 EJS42280.1 - 5.6e-09 35.6 5.6 5.6e-09 35.6 3.9 4.2 3 2 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 EJS42280.1 - 0.0011 18.6 2.8 0.0011 18.6 1.9 4.7 5 1 0 5 5 5 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EJS42280.1 - 0.003 17.1 6.0 0.003 17.1 4.2 5.2 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EJS42280.1 - 0.013 15.4 6.1 0.013 15.4 4.3 4.8 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EJS42280.1 - 0.023 14.3 32.2 0.097 12.4 4.1 5.3 5 0 0 5 5 5 0 zinc-RING finger domain HrpA_pilin PF09589.5 EJS42280.1 - 0.025 15.0 0.1 0.048 14.0 0.1 1.5 1 1 0 1 1 1 0 HrpA pilus formation protein zf-C3HC4_4 PF15227.1 EJS42280.1 - 4.4 7.2 27.1 2.3 8.1 3.4 4.9 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING BHD_2 PF10404.4 EJS42281.1 - 3.8e-11 43.1 0.3 1.8e-10 40.9 0.2 2.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EJS42281.1 - 2e-10 40.0 0.0 1.1e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.4 EJS42281.1 - 8e-10 38.2 0.0 1.9e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EJS42281.1 - 0.00014 21.2 0.4 0.00062 19.1 0.3 2.1 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain Ins_P5_2-kin PF06090.7 EJS42282.1 - 4.7e-49 167.1 5.3 1.4e-48 165.5 3.7 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Methyltransf_23 PF13489.1 EJS42283.1 - 9.4e-17 61.1 0.0 1.7e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EJS42283.1 - 8.4e-15 55.0 0.1 6.1e-14 52.2 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EJS42283.1 - 1.1e-10 41.0 0.5 9.3e-09 34.7 0.0 2.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EJS42283.1 - 1.8e-09 37.9 0.0 7.2e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EJS42283.1 - 4.6e-09 36.0 2.4 1.2e-08 34.6 0.0 2.6 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS42283.1 - 6.8e-08 33.0 0.0 2e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EJS42283.1 - 6.9e-08 32.7 0.0 1.7e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain COX16 PF14138.1 EJS42283.1 - 0.44 10.7 10.1 0.19 11.8 3.6 3.0 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 HIM1 PF08732.5 EJS42284.1 - 1.6e-150 501.1 0.5 1.8e-150 500.9 0.3 1.0 1 0 0 1 1 1 1 HIM1 Scs3p PF10261.4 EJS42285.1 - 2.7e-39 134.6 20.5 6.6e-39 133.3 14.2 1.6 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 EJS42285.1 - 0.0048 16.5 4.5 0.0048 16.5 3.1 2.4 3 0 0 3 3 3 1 PAP2 superfamily Orai-1 PF07856.7 EJS42285.1 - 0.028 13.9 5.6 0.055 13.0 3.8 1.5 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF4212 PF13937.1 EJS42285.1 - 5.6 7.0 12.4 0.055 13.4 2.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Ubiq-assoc PF09145.5 EJS42286.1 - 2.2e-20 72.2 3.6 3.5e-20 71.5 1.7 2.0 2 0 0 2 2 2 1 Ubiquitin-associated TPR_11 PF13414.1 EJS42286.1 - 5.5e-09 35.5 0.0 9.6e-06 25.1 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EJS42286.1 - 1.8e-07 30.9 0.0 7.7e-05 22.5 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EJS42286.1 - 8.2e-06 25.3 0.0 0.53 10.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EJS42286.1 - 7.3e-05 22.2 0.0 1.8 8.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EJS42286.1 - 0.0031 17.1 1.8 11 6.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DnaJ PF00226.26 EJS42286.1 - 0.0037 16.9 0.6 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain Apis_Csd PF11671.3 EJS42286.1 - 0.011 15.5 0.1 0.031 14.0 0.1 1.7 1 0 0 1 1 1 0 Complementary sex determiner protein TPR_6 PF13174.1 EJS42286.1 - 0.04 14.3 0.0 2.1 8.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DASH_Dad4 PF08650.5 EJS42287.1 - 1.1e-38 131.0 5.2 1.2e-38 130.8 3.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 NPV_P10 PF05531.7 EJS42287.1 - 0.026 14.7 0.4 0.029 14.6 0.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Asparaginase PF00710.15 EJS42288.1 - 9.7e-74 248.0 0.0 1.1e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Ribosomal_L19 PF01245.15 EJS42288.1 - 0.059 13.1 0.0 7.6 6.3 0.0 2.6 2 1 0 2 2 2 0 Ribosomal protein L19 PBP PF01161.15 EJS42289.1 - 2.3e-12 46.9 0.0 3.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ATP-synt_E PF05680.7 EJS42290.1 - 6.8e-17 61.2 0.0 7.6e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain FYVE PF01363.16 EJS42291.1 - 3e-18 65.4 23.2 5.8e-15 54.9 1.5 3.3 3 0 0 3 3 3 2 FYVE zinc finger zf-ribbon_3 PF13248.1 EJS42291.1 - 0.0017 17.5 1.8 0.0017 17.5 1.2 3.3 4 0 0 4 4 4 1 zinc-ribbon domain Rbsn PF11464.3 EJS42291.1 - 0.0025 17.3 0.7 0.0025 17.3 0.5 2.7 3 0 0 3 3 3 1 Rabenosyn Rab binding domain zf-C2H2_4 PF13894.1 EJS42291.1 - 0.012 15.8 0.1 0.012 15.8 0.1 4.9 5 2 0 5 5 5 0 C2H2-type zinc finger HypA PF01155.14 EJS42291.1 - 0.16 11.6 10.2 0.51 10.0 1.4 3.2 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-C2H2 PF00096.21 EJS42291.1 - 0.21 12.0 0.1 0.21 12.0 0.0 5.4 5 1 1 6 6 6 0 Zinc finger, C2H2 type Siva PF05458.7 EJS42291.1 - 0.62 9.6 8.5 4 6.9 2.2 2.4 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Uds1 PF15456.1 EJS42291.1 - 2 8.4 14.2 0.56 10.2 2.6 3.6 3 1 1 4 4 4 0 Up-regulated During Septation CorA PF01544.13 EJS42291.1 - 8.9 5.2 8.6 2.6 7.0 1.0 2.5 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein GRAM PF02893.15 EJS42292.1 - 2.3e-18 65.4 0.0 5.3e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Curto_V3 PF07436.6 EJS42292.1 - 8.6 6.5 6.7 0.51 10.5 0.1 2.4 3 0 0 3 3 3 0 Curtovirus V3 protein Skp1 PF01466.14 EJS42293.1 - 6.8e-37 125.3 0.2 1.1e-36 124.7 0.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EJS42293.1 - 3.4e-14 52.6 0.1 2.1e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain GCIP PF13324.1 EJS42293.1 - 0.0087 15.3 4.5 0.012 14.8 3.1 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Ebola_NP PF05505.7 EJS42293.1 - 0.4 8.6 5.6 0.46 8.4 3.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DCA16 PF15349.1 EJS42293.1 - 1.3 8.3 3.3 1.9 7.8 2.3 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 CDC45 PF02724.9 EJS42293.1 - 1.4 6.8 13.8 1.7 6.5 9.3 1.3 1 1 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 EJS42293.1 - 2.6 5.7 16.9 3.2 5.3 11.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.5 EJS42293.1 - 3.3 7.9 24.8 0.25 11.5 10.2 2.3 1 1 1 2 2 2 0 Centromere protein B dimerisation domain SDA1 PF05285.7 EJS42293.1 - 5.7 6.1 11.1 7.8 5.6 7.7 1.2 1 0 0 1 1 1 0 SDA1 Peptidase_C13 PF01650.13 EJS42294.1 - 3.4e-46 157.6 1.3 4.6e-46 157.1 0.9 1.1 1 0 0 1 1 1 1 Peptidase C13 family ResIII PF04851.10 EJS42295.1 - 7.6e-23 81.2 1.3 1.6e-22 80.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EJS42295.1 - 1.5e-16 60.3 0.6 2.5e-16 59.6 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS42295.1 - 5.8e-14 51.7 0.0 2.4e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EJS42295.1 - 1.3e-05 25.3 0.0 4.4e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EJS42295.1 - 0.0024 16.9 0.0 0.006 15.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_C_2 PF13307.1 EJS42295.1 - 0.096 12.6 0.9 0.29 11.0 0.0 2.3 3 0 0 3 3 3 0 Helicase C-terminal domain SNF2_N PF00176.18 EJS42296.1 - 2.5e-77 259.6 2.3 3.9e-77 259.0 0.5 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain HSA PF07529.8 EJS42296.1 - 6.3e-17 61.1 8.4 6.3e-17 61.1 5.8 3.5 3 1 1 4 4 4 1 HSA Helicase_C PF00271.26 EJS42296.1 - 2e-14 53.2 0.0 9.5e-14 51.0 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EJS42296.1 - 1.3e-06 28.0 0.0 3.7e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_L20 PF00453.13 EJS42297.1 - 0.063 13.2 1.5 14 5.6 0.1 2.8 2 0 0 2 2 2 0 Ribosomal protein L20 Ribosomal_S15 PF00312.17 EJS42298.1 - 1.6e-29 101.5 0.2 3.7e-29 100.3 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 DUF3487 PF11990.3 EJS42298.1 - 0.0064 15.8 0.2 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3487) MatE PF01554.13 EJS42299.1 - 2.2e-60 202.9 34.0 1.2e-36 125.7 5.4 2.8 3 0 0 3 3 3 2 MatE Fcf1 PF04900.7 EJS42300.1 - 1.5e-37 127.6 1.3 1.8e-37 127.4 0.1 1.7 2 0 0 2 2 2 1 Fcf1 tRNA-synt_1d PF00750.14 EJS42301.1 - 7.9e-104 347.2 5.4 1e-103 346.9 3.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EJS42301.1 - 4.2e-30 104.1 0.1 9.8e-29 99.7 0.0 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EJS42301.1 - 2.3e-10 40.8 0.1 1.7e-09 38.0 0.0 2.5 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain Amidase PF01425.16 EJS42302.1 - 1.2e-93 314.3 0.0 1.5e-93 314.1 0.0 1.1 1 0 0 1 1 1 1 Amidase SLX9 PF15341.1 EJS42302.1 - 0.099 13.0 1.6 0.17 12.3 1.1 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DEAD PF00270.24 EJS42303.1 - 1.3e-44 151.6 0.4 3.2e-41 140.6 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS42303.1 - 7.6e-27 92.9 0.2 1.9e-26 91.7 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EJS42303.1 - 5.9e-05 22.9 0.1 0.00016 21.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TPR_11 PF13414.1 EJS42304.1 - 3.4e-24 84.2 10.8 1.3e-11 43.9 0.1 4.4 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EJS42304.1 - 9.2e-21 72.5 2.7 1.1e-06 28.0 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EJS42304.1 - 7.5e-19 66.0 1.4 2.9e-05 23.6 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EJS42304.1 - 4.2e-16 58.0 0.2 0.00073 19.9 0.2 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EJS42304.1 - 3.6e-15 56.1 1.4 2.2e-05 24.9 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EJS42304.1 - 4.3e-15 54.5 3.5 0.0028 17.7 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EJS42304.1 - 4.2e-10 39.8 1.5 0.019 15.3 0.0 4.3 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EJS42304.1 - 5.4e-10 38.3 1.7 0.23 11.3 0.0 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EJS42304.1 - 1.9e-07 30.8 2.8 8.4e-05 22.4 0.0 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 EJS42304.1 - 2.1e-07 30.9 0.1 0.57 10.3 0.0 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EJS42304.1 - 2.2e-06 27.4 0.2 0.021 14.6 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 EJS42304.1 - 2.2e-06 27.7 0.1 5.2 7.7 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EJS42304.1 - 0.00083 18.4 0.6 0.059 12.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EJS42304.1 - 0.002 17.7 0.1 0.35 10.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2989 PF11207.3 EJS42304.1 - 0.02 14.3 0.1 0.054 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) BTAD PF03704.12 EJS42304.1 - 0.039 14.2 0.0 0.15 12.3 0.0 2.0 1 1 0 1 1 1 0 Bacterial transcriptional activator domain Glyco_transf_34 PF05637.7 EJS42305.1 - 1.7e-80 270.0 0.1 2.1e-80 269.6 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EJS42305.1 - 0.002 17.4 0.0 0.083 12.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.11 EJS42305.1 - 0.0073 16.1 0.2 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Sybindin PF04099.7 EJS42306.1 - 5.9e-35 120.0 3.8 1e-13 51.2 0.2 3.1 3 0 0 3 3 3 3 Sybindin-like family Sedlin_N PF04628.8 EJS42306.1 - 6.6e-07 29.2 0.3 4.8e-06 26.4 0.1 2.0 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region TraU PF06834.6 EJS42306.1 - 0.0042 16.2 0.0 0.0076 15.4 0.0 1.4 2 0 0 2 2 2 1 TraU protein Pkinase PF00069.20 EJS42307.1 - 6.1e-51 173.0 0.7 1.1e-48 165.6 0.5 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42307.1 - 4.7e-22 78.3 0.0 3.4e-20 72.1 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EJS42307.1 - 1.3e-06 27.5 0.0 2.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EJS42307.1 - 0.015 15.0 0.2 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EJS42307.1 - 0.11 11.3 5.6 0.13 11.0 3.2 1.5 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase Aha1_N PF09229.6 EJS42308.1 - 6.8e-39 132.8 0.3 2.6e-38 130.9 0.0 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EJS42308.1 - 3.4e-10 40.0 0.1 5.8e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein zf-C2H2 PF00096.21 EJS42309.1 - 3.2e-10 39.7 10.3 4.1e-05 23.6 1.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS42309.1 - 3.7e-07 30.0 11.9 0.0015 18.7 2.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EJS42309.1 - 1.8e-05 24.8 7.1 1.8e-05 24.8 4.9 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EJS42309.1 - 5e-05 23.3 3.8 0.0068 16.5 0.6 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type F-box PF00646.28 EJS42310.1 - 3.5e-07 29.7 0.2 9.5e-07 28.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EJS42310.1 - 4.7e-06 26.2 0.0 9.3e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EJS42310.1 - 0.045 13.7 2.0 0.28 11.1 0.1 3.2 2 0 0 2 2 2 0 PRANC domain Svf1 PF08622.5 EJS42311.1 - 3.1e-102 341.9 0.4 3.8e-102 341.6 0.2 1.1 1 0 0 1 1 1 1 Svf1-like HNH PF01844.18 EJS42311.1 - 0.0056 16.5 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Histone PF00125.19 EJS42312.1 - 1.4e-21 76.3 0.3 2e-21 75.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EJS42312.1 - 6.6e-06 26.0 0.1 1.4e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EJS42312.1 - 0.0013 18.9 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 EJS42312.1 - 0.038 12.6 3.0 0.046 12.3 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1018 PF06252.7 EJS42312.1 - 0.095 13.2 0.6 0.13 12.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Histone PF00125.19 EJS42313.1 - 6.5e-26 90.2 0.0 8.8e-26 89.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EJS42313.1 - 9.8e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ADK PF00406.17 EJS42314.1 - 2e-60 203.0 0.0 2.3e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EJS42314.1 - 5.7e-14 51.4 0.0 1.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EJS42314.1 - 1.1e-07 31.7 0.0 2.2e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EJS42314.1 - 5.1e-06 27.3 0.0 9.8e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EJS42314.1 - 0.00013 22.2 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EJS42314.1 - 0.0098 15.0 0.1 0.019 14.1 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 EJS42314.1 - 0.083 13.0 0.0 0.97 9.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain Herpes_UL36 PF03586.8 EJS42315.1 - 0.018 14.1 0.1 0.087 11.9 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein MalF_P2 PF14785.1 EJS42315.1 - 0.031 14.1 0.8 0.067 13.0 0.6 1.5 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain BMFP PF04380.8 EJS42315.1 - 0.038 14.1 0.7 0.14 12.3 0.5 2.0 1 0 0 1 1 1 0 Membrane fusogenic activity DUF3767 PF12597.3 EJS42316.1 - 3.7e-42 142.7 0.2 3.7e-42 142.7 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3767) Aminotran_1_2 PF00155.16 EJS42317.1 - 2.7e-73 247.0 0.3 1.2e-72 244.8 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EJS42317.1 - 2.9e-08 32.4 0.0 2.9e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EJS42317.1 - 2.3e-06 26.5 0.0 5.9e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EJS42317.1 - 0.0027 16.8 1.2 0.59 9.1 0.0 2.4 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_60s PF00428.14 EJS42317.1 - 3.2 8.2 10.7 8.9 6.7 7.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Aconitase PF00330.15 EJS42318.1 - 9.2e-74 248.5 0.2 1.5e-70 237.9 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EJS42318.1 - 4.9e-36 123.7 0.1 1.4e-35 122.2 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain Flavokinase PF01687.12 EJS42319.1 - 5.7e-31 106.9 0.0 9.2e-31 106.3 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_L5_C PF00673.16 EJS42320.1 - 4.1e-24 84.1 0.1 1.3e-23 82.5 0.0 1.9 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EJS42320.1 - 1.8e-05 24.3 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Adaptin_N PF01602.15 EJS42321.1 - 4e-119 398.3 11.0 6.4e-119 397.6 7.6 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EJS42321.1 - 4.9e-60 200.9 0.0 1.3e-59 199.5 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EJS42321.1 - 1.3e-50 170.7 0.1 1.3e-50 170.7 0.0 2.2 3 0 0 3 3 3 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EJS42321.1 - 4.5e-05 23.6 6.3 0.03 14.6 0.0 4.6 2 1 3 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EJS42321.1 - 0.0055 17.0 0.1 0.031 14.6 0.1 2.3 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region Swi5 PF07061.6 EJS42322.1 - 0.0004 20.0 1.5 0.0052 16.5 0.1 2.6 2 0 0 2 2 2 1 Swi5 zf-CCCH PF00642.19 EJS42323.1 - 4.8e-18 64.3 16.1 4.4e-09 35.8 4.4 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EJS42323.1 - 1.4 9.0 12.6 2.1 8.4 0.9 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type RWD PF05773.17 EJS42324.1 - 1.5e-22 79.6 5.3 3.4e-22 78.4 3.6 1.6 1 1 0 1 1 1 1 RWD domain ENTH PF01417.15 EJS42325.1 - 5.4e-30 103.8 0.1 1.1e-29 102.8 0.1 1.5 1 0 0 1 1 1 1 ENTH domain Cas_Csy4 PF09618.5 EJS42325.1 - 0.009 15.8 3.9 0.0092 15.8 1.5 1.8 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Csy4) DUF2756 PF10956.3 EJS42325.1 - 0.13 12.5 5.7 0.36 11.0 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) PcfK PF14058.1 EJS42325.1 - 0.99 9.5 10.4 0.048 13.8 2.8 2.1 3 0 0 3 3 3 0 PcfK-like protein Pro_isomerase PF00160.16 EJS42326.1 - 2.2e-46 157.8 0.1 2.4e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Semialdhyde_dhC PF02774.13 EJS42327.1 - 3.6e-44 150.8 0.0 5.3e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EJS42327.1 - 1.8e-32 112.1 0.0 3e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EJS42327.1 - 0.018 15.6 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 EJS42327.1 - 0.044 13.6 0.0 0.099 12.5 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EJS42327.1 - 0.073 12.0 0.2 0.13 11.2 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase AA_permease PF00324.16 EJS42328.1 - 1.9e-74 250.7 35.4 2.5e-74 250.3 24.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS42328.1 - 3.5e-31 108.1 42.6 1.6e-30 106.0 29.1 2.1 1 1 0 1 1 1 1 Amino acid permease TPR_11 PF13414.1 EJS42329.1 - 5e-06 26.0 0.3 0.11 12.1 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EJS42329.1 - 1.8e-05 24.2 2.1 0.66 10.0 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EJS42329.1 - 2.8e-05 23.5 0.2 0.46 10.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EJS42329.1 - 0.00014 22.1 0.8 0.065 13.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EJS42329.1 - 0.00039 20.9 2.8 2.3 9.0 0.2 4.4 4 2 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EJS42329.1 - 0.0015 18.6 0.5 0.3 11.2 0.1 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EJS42329.1 - 0.0016 18.9 0.1 1.3 9.8 0.0 3.9 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EJS42329.1 - 0.0063 16.2 0.1 0.43 10.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EJS42329.1 - 0.041 13.7 0.0 7.2 6.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EJS42329.1 - 0.07 12.9 0.1 38 4.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1125 PF06563.6 EJS42329.1 - 0.074 12.7 0.2 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) TPR_15 PF13429.1 EJS42329.1 - 0.095 11.7 0.1 1.7 7.6 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SH3_1 PF00018.23 EJS42330.1 - 3e-13 48.9 0.0 6.7e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EJS42330.1 - 1.3e-12 47.0 0.0 3.1e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EJS42330.1 - 1e-05 24.9 0.1 2.7e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain VEFS-Box PF09733.4 EJS42330.1 - 0.3 10.7 3.2 0.66 9.6 2.2 1.6 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Cwf_Cwc_15 PF04889.7 EJS42331.1 - 4.8e-15 55.9 18.6 4.1e-09 36.5 1.7 3.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein Sec1 PF00995.18 EJS42332.1 - 2.8e-99 333.2 4.3 3.3e-99 333.0 3.0 1.0 1 0 0 1 1 1 1 Sec1 family WD40 PF00400.27 EJS42333.1 - 4.4e-08 32.6 3.3 0.0018 18.1 0.5 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat CPSF_A PF03178.10 EJS42333.1 - 1.2e-06 27.8 1.1 8.9e-06 25.0 0.1 2.6 2 1 0 2 2 2 1 CPSF A subunit region Pro_isomerase PF00160.16 EJS42333.1 - 0.033 14.4 0.5 2.1 8.5 0.0 2.5 3 0 0 3 3 3 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Eapp_C PF10238.4 EJS42333.1 - 0.05 13.5 0.1 0.05 13.5 0.0 1.9 2 0 0 2 2 2 0 E2F-associated phosphoprotein Sec5 PF15469.1 EJS42334.1 - 5.7e-42 143.4 13.0 5.7e-42 143.4 9.0 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EJS42334.1 - 0.00053 19.7 4.8 0.00053 19.7 3.3 3.0 2 1 1 3 3 3 1 Vps51/Vps67 TFIID_30kDa PF03540.8 EJS42335.1 - 2.7e-26 91.1 0.1 4.1e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CDC37_N PF03234.9 EJS42336.1 - 2e-63 213.9 13.0 2e-63 213.9 9.0 3.2 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EJS42336.1 - 1.7e-49 167.6 7.2 6.7e-49 165.6 5.0 2.1 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EJS42336.1 - 4.6e-22 77.7 5.3 4.6e-22 77.7 3.7 2.4 3 0 0 3 3 3 1 Cdc37 C terminal domain Stb3 PF10330.4 EJS42337.1 - 8.6e-33 111.8 0.0 1.6e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein IPK PF03770.11 EJS42338.1 - 6.3e-55 185.8 0.2 7.8e-55 185.5 0.1 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase ASFV_360 PF01671.11 EJS42338.1 - 0.04 13.3 0.2 0.065 12.6 0.2 1.3 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein Bd3614-deam PF14439.1 EJS42338.1 - 0.91 9.3 3.1 1.8 8.3 2.1 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase HMG_box PF00505.14 EJS42339.1 - 2.9e-11 43.4 3.4 2.9e-11 43.4 2.3 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EJS42339.1 - 7e-09 35.9 2.2 7e-09 35.9 1.5 1.7 2 0 0 2 2 2 1 HMG-box domain Syntaxin_2 PF14523.1 EJS42339.1 - 0.048 13.6 2.0 0.49 10.4 0.9 2.5 2 0 0 2 2 2 0 Syntaxin-like protein Alpha_adaptin_C PF02296.11 EJS42339.1 - 0.15 12.0 0.3 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain Ada3 PF10198.4 EJS42340.1 - 1.7e-45 153.9 3.6 1.7e-45 153.9 2.5 2.5 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 UQ_con PF00179.21 EJS42341.1 - 8.4e-44 148.3 0.0 1.1e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EJS42341.1 - 1.8e-30 104.2 1.3 2.9e-30 103.6 0.9 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_2 PF08587.6 EJS42341.1 - 0.032 14.4 0.1 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) RWD PF05773.17 EJS42341.1 - 0.043 13.7 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 RWD domain CybS PF05328.7 EJS42342.1 - 2e-48 163.3 0.0 2.5e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 CybS BAH PF01426.13 EJS42343.1 - 0.0089 15.7 0.4 0.011 15.4 0.3 1.3 1 0 0 1 1 1 1 BAH domain PCI PF01399.22 EJS42343.1 - 0.011 16.0 0.9 0.021 15.1 0.2 1.8 2 0 0 2 2 2 0 PCI domain Cyclin_N PF00134.18 EJS42343.1 - 0.014 14.9 0.4 0.024 14.2 0.2 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain PXA PF02194.10 EJS42344.1 - 4.5e-09 36.1 2.2 3.7e-08 33.1 0.1 2.8 2 1 1 3 3 3 1 PXA domain IBN_N PF03810.14 EJS42344.1 - 0.053 13.4 0.1 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain Nipped-B_C PF12830.2 EJS42345.1 - 3.3e-39 134.4 1.7 3.3e-39 134.4 1.2 4.5 4 1 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EJS42345.1 - 1.2e-13 50.6 4.2 2.5e-13 49.6 1.0 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HHH_7 PF14635.1 EJS42345.1 - 0.0029 17.6 0.3 0.017 15.2 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HEAT_2 PF13646.1 EJS42345.1 - 0.011 15.9 0.0 1.1 9.6 0.0 3.1 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.17 EJS42345.1 - 0.016 15.2 4.9 34 4.8 0.1 5.7 6 0 0 6 6 6 0 HEAT repeat SAS4 PF15460.1 EJS42346.1 - 2.3e-30 104.4 5.3 2.3e-30 104.4 3.7 2.6 3 0 0 3 3 3 1 Something about silencing, SAS, complex subunit 4 Metallophos PF00149.23 EJS42347.1 - 2.2e-17 63.1 1.0 3.4e-17 62.4 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF912 PF06024.7 EJS42347.1 - 0.018 15.0 0.4 4.9 7.2 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0233 PF06781.7 EJS42347.1 - 0.12 12.0 7.8 0.19 11.3 0.9 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) DUF2077 PF09850.4 EJS42347.1 - 0.15 11.4 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) PRELI PF04707.9 EJS42348.1 - 6.2e-56 188.3 0.4 7.4e-56 188.0 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family Cpn60_TCP1 PF00118.19 EJS42350.1 - 4.1e-146 487.3 0.8 4.7e-146 487.2 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sec1 PF00995.18 EJS42351.1 - 3.5e-143 478.2 8.2 3.5e-143 478.2 5.7 1.3 2 0 0 2 2 2 1 Sec1 family TIP49 PF06068.8 EJS42352.1 - 1e-188 627.0 0.6 1.2e-188 626.8 0.4 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EJS42352.1 - 5.5e-09 35.4 2.3 0.00013 21.0 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EJS42352.1 - 2.1e-08 34.4 1.1 8.5e-05 22.7 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EJS42352.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EJS42352.1 - 0.0018 18.3 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EJS42352.1 - 0.0061 16.2 0.1 0.021 14.5 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EJS42352.1 - 0.011 14.8 0.1 0.027 13.5 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 EJS42352.1 - 0.013 15.3 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EJS42352.1 - 0.02 14.6 0.2 0.69 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EJS42352.1 - 0.022 13.9 0.1 4 6.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 EJS42352.1 - 0.024 13.4 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain CPT PF07931.7 EJS42352.1 - 0.043 13.4 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ORC3_N PF07034.6 EJS42352.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus DEAD PF00270.24 EJS42354.1 - 1.4e-43 148.3 0.6 6.5e-41 139.6 0.1 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS42354.1 - 3.4e-21 74.9 0.0 8e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EJS42354.1 - 3.4e-05 23.7 3.7 5.3e-05 23.1 0.1 2.6 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EJS42354.1 - 0.0039 17.1 0.1 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DUF2201 PF09967.4 EJS42354.1 - 0.044 13.7 0.0 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 VWA-like domain (DUF2201) AAA_30 PF13604.1 EJS42354.1 - 0.044 13.3 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 EJS42356.1 - 1.7e-66 223.0 0.0 2.1e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EJS42356.1 - 2e-08 35.0 0.1 3.4e-08 34.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EJS42356.1 - 0.00012 22.3 0.1 0.00043 20.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EJS42356.1 - 0.00065 19.6 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 2 Cytidylate kinase-like family AAA_33 PF13671.1 EJS42356.1 - 0.0011 18.8 0.1 0.0062 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 EJS42356.1 - 0.0015 18.4 0.1 0.033 14.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase AAA_28 PF13521.1 EJS42356.1 - 0.0019 18.2 0.0 0.0044 17.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EJS42356.1 - 0.01 14.9 0.1 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ApbA_C PF08546.6 EJS42357.1 - 5.4e-19 68.4 0.0 1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal FHA PF00498.21 EJS42358.1 - 4.9e-16 58.6 0.6 4.9e-16 58.6 0.4 3.1 3 1 1 4 4 4 1 FHA domain DASH_Spc19 PF08287.6 EJS42359.1 - 5.4e-43 146.2 8.6 6.1e-43 146.0 6.0 1.0 1 0 0 1 1 1 1 Spc19 DASH_Dad2 PF08654.5 EJS42359.1 - 0.11 12.4 11.4 2.6 8.0 1.7 3.2 3 0 0 3 3 3 0 DASH complex subunit Dad2 Laminin_II PF06009.7 EJS42359.1 - 3.3 7.4 8.6 1.4 8.6 0.1 2.9 2 1 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 EJS42359.1 - 5.8 6.7 6.8 14 5.4 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 EJS42359.1 - 6.3 6.7 9.4 17 5.4 0.1 3.7 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Rogdi_lz PF10259.4 EJS42360.1 - 7.3e-84 281.0 4.5 8.3e-84 280.9 3.1 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Cation_efflux PF01545.16 EJS42361.1 - 1.2e-55 188.6 4.7 1.2e-55 188.6 3.2 3.0 3 1 0 3 3 3 1 Cation efflux family UreE_C PF05194.7 EJS42361.1 - 2.9 8.0 13.5 11 6.1 0.7 2.6 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain SelP_N PF04592.9 EJS42361.1 - 3.7 6.8 11.5 1.7 7.9 2.4 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region EST1_DNA_bind PF10373.4 EJS42362.1 - 2.3e-47 161.5 1.9 3.8e-47 160.8 0.4 2.0 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EJS42362.1 - 2.2e-22 79.4 0.8 2.2e-22 79.4 0.5 2.7 2 1 0 2 2 2 1 Telomerase activating protein Est1 Zn_clus PF00172.13 EJS42363.1 - 4.4e-09 36.0 8.5 8.3e-09 35.2 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1067 PF06362.6 EJS42363.1 - 1.3 9.5 11.7 1.4 9.5 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1067) PIP5K PF01504.13 EJS42364.1 - 1.2e-83 280.1 2.3 2.4e-83 279.1 1.6 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CYSTM PF12734.2 EJS42365.1 - 2.5e-07 30.6 24.3 2.5e-07 30.6 16.9 4.5 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 EJS42365.1 - 0.11 12.5 20.8 0.13 12.3 14.4 1.1 1 0 0 1 1 1 0 Proline-rich DUF3105 PF11303.3 EJS42365.1 - 4.3 7.1 5.7 5.4 6.8 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) W2 PF02020.13 EJS42366.1 - 2.9e-15 55.9 5.5 8.6e-15 54.4 3.8 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EJS42366.1 - 1.1e-10 40.4 15.3 0.0025 17.2 0.9 4.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EJS42366.1 - 8.3e-09 35.1 0.0 1.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EJS42366.1 - 0.0095 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EJS42366.1 - 0.073 12.6 16.7 13 5.4 3.6 4.3 2 2 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Cpn60_TCP1 PF00118.19 EJS42367.1 - 1.5e-141 472.3 11.8 1.8e-141 472.1 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans_2 PF11951.3 EJS42368.1 - 5e-12 45.1 0.1 5e-12 45.1 0.1 3.0 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS42368.1 - 3.7e-08 33.1 10.5 6e-08 32.4 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cg6151-P PF10233.4 EJS42369.1 - 1.3e-39 134.6 14.7 1.7e-39 134.2 10.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P ATG22 PF11700.3 EJS42369.1 - 0.043 12.2 8.6 0.064 11.7 6.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like HMG_box PF00505.14 EJS42370.1 - 6.3e-36 122.4 8.0 5.7e-21 74.5 0.8 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EJS42370.1 - 2.5e-16 59.7 4.9 5.1e-11 42.7 0.6 2.2 2 0 0 2 2 2 2 HMG-box domain Syntaxin_2 PF14523.1 EJS42370.1 - 0.0057 16.6 2.4 1.5 8.8 0.2 2.4 2 0 0 2 2 2 2 Syntaxin-like protein DUF1074 PF06382.6 EJS42370.1 - 0.03 14.3 1.1 0.51 10.2 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1074) DUF4163 PF13739.1 EJS42370.1 - 0.031 15.0 2.0 0.035 14.8 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) HeLo PF14479.1 EJS42370.1 - 0.054 13.2 0.4 0.091 12.4 0.3 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF1002 PF06207.6 EJS42370.1 - 0.11 11.7 0.7 12 5.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) NYD-SP28_assoc PF14775.1 EJS42370.1 - 0.2 11.3 2.1 1.9 8.2 0.1 2.6 3 0 0 3 3 3 0 Sperm tail C-terminal domain Cyt-b5 PF00173.23 EJS42371.1 - 1.7e-13 50.1 0.0 2.4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain dsDNA_bind PF01984.15 EJS42372.1 - 7.7e-26 90.1 0.1 9.4e-26 89.9 0.1 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.4 EJS42372.1 - 0.24 11.5 0.1 0.24 11.5 0.1 2.8 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region HEAT PF02985.17 EJS42373.1 - 1.8e-05 24.4 0.2 6.9 7.0 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EJS42373.1 - 0.00064 19.9 0.1 0.47 10.7 0.0 4.6 5 1 2 7 7 7 2 HEAT repeats FANCI_S2 PF14676.1 EJS42373.1 - 0.071 13.0 10.6 3 7.7 0.2 4.7 4 1 0 4 4 4 0 FANCI solenoid 2 Snf7 PF03357.16 EJS42374.1 - 3.3e-40 137.2 11.2 4.4e-40 136.8 7.7 1.1 1 0 0 1 1 1 1 Snf7 DUF4407 PF14362.1 EJS42374.1 - 0.041 12.8 2.7 0.043 12.7 1.6 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HHH_2 PF12826.2 EJS42374.1 - 0.11 12.3 0.4 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif SlyX PF04102.7 EJS42374.1 - 0.26 11.6 10.5 0.35 11.2 0.8 3.0 3 1 0 3 3 3 0 SlyX DUF2203 PF09969.4 EJS42374.1 - 0.3 11.3 2.8 0.65 10.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.6 EJS42374.1 - 6.6 6.6 7.7 1.2 9.0 1.5 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DivIVA PF05103.8 EJS42374.1 - 6.8 6.7 11.6 0.57 10.2 2.6 2.6 2 2 0 2 2 2 0 DivIVA protein AAA PF00004.24 EJS42375.1 - 4.7e-11 43.0 0.1 1.8e-10 41.0 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EJS42375.1 - 5.5e-09 35.2 3.0 0.00021 20.1 0.2 3.2 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EJS42375.1 - 0.00018 20.6 0.0 0.0014 17.7 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EJS42375.1 - 0.00047 20.2 0.1 0.014 15.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EJS42375.1 - 0.0016 18.3 0.0 0.0049 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EJS42375.1 - 0.0025 17.8 0.0 0.0076 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EJS42375.1 - 0.0099 15.7 0.0 0.029 14.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EJS42375.1 - 0.014 14.9 2.3 0.042 13.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EJS42375.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EJS42375.1 - 0.016 16.0 0.1 0.073 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EJS42375.1 - 0.059 13.1 0.1 0.47 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EJS42375.1 - 3.7 7.8 6.8 6.3 7.0 0.0 4.0 5 0 0 5 5 5 0 ABC transporter UPF1_Zn_bind PF09416.5 EJS42376.1 - 9.2e-71 236.3 8.6 9.2e-71 236.3 6.0 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EJS42376.1 - 2e-57 193.8 0.0 3.9e-57 192.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EJS42376.1 - 5.4e-52 176.7 0.8 1e-51 175.8 0.5 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EJS42376.1 - 2e-16 60.1 0.1 1.2e-11 44.5 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EJS42376.1 - 8.8e-13 47.8 0.1 2.9e-12 46.1 0.1 1.8 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 EJS42376.1 - 6.4e-06 26.1 0.6 4.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EJS42376.1 - 7.7e-06 25.1 0.1 8.9e-05 21.6 0.0 2.7 2 2 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EJS42376.1 - 4.7e-05 23.0 0.0 0.52 9.7 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EJS42376.1 - 0.0042 16.7 0.0 0.0089 15.6 0.0 1.5 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EJS42376.1 - 0.0048 15.9 0.0 0.61 8.9 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase PhoH PF02562.11 EJS42376.1 - 0.0076 15.5 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 EJS42376.1 - 0.023 13.6 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.24 EJS42376.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase HEM4 PF02602.10 EJS42376.1 - 0.064 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD AAA_22 PF13401.1 EJS42376.1 - 0.08 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EJS42376.1 - 0.096 12.6 1.8 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_S13_N PF08069.7 EJS42376.1 - 0.16 11.7 0.0 0.58 10.0 0.0 1.9 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain ADH_N PF08240.7 EJS42378.1 - 2.2e-31 107.8 0.3 3.7e-31 107.1 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EJS42378.1 - 3e-27 94.7 0.1 4.5e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EJS42378.1 - 9.7e-06 26.5 0.0 3e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Peptidase_M41 PF01434.13 EJS42380.1 - 1.7e-74 249.8 1.5 2e-74 249.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 EJS42380.1 - 2.8e-42 144.0 0.0 8.7e-42 142.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EJS42380.1 - 5.8e-10 39.3 0.4 2.3e-09 37.4 0.3 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 EJS42380.1 - 0.00029 21.6 2.3 0.00045 21.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 EJS42380.1 - 0.0016 18.1 0.1 0.0064 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EJS42380.1 - 0.0021 17.1 0.0 0.0046 16.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EJS42380.1 - 0.0028 16.4 0.0 0.0058 15.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 EJS42380.1 - 0.0037 17.1 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EJS42380.1 - 0.0042 16.7 0.4 0.012 15.3 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EJS42380.1 - 0.0054 16.8 0.1 0.16 12.1 0.1 2.9 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EJS42380.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EJS42380.1 - 0.026 14.5 0.2 0.12 12.3 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EJS42380.1 - 0.046 13.5 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EJS42380.1 - 0.058 12.7 1.3 0.24 10.7 0.3 2.2 1 1 1 2 2 2 0 AAA domain Siah-Interact_N PF09032.6 EJS42380.1 - 0.16 12.0 5.0 0.66 10.0 3.5 2.0 1 0 0 1 1 1 0 Siah interacting protein, N terminal AAA_18 PF13238.1 EJS42380.1 - 0.4 10.9 0.0 0.4 10.9 0.0 3.3 3 1 0 3 3 3 0 AAA domain DUF2407_C PF13373.1 EJS42380.1 - 0.59 10.0 3.8 1.6 8.6 2.6 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain NAD_binding_10 PF13460.1 EJS42381.1 - 7.1e-26 91.3 0.0 8.3e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EJS42381.1 - 1.9e-09 36.6 0.7 3e-09 35.9 0.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EJS42381.1 - 1.1e-07 31.3 0.1 1.9e-07 30.5 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EJS42381.1 - 1.8e-06 28.2 0.1 2.7e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EJS42381.1 - 4.1e-06 26.4 0.3 8.4e-06 25.3 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EJS42381.1 - 2e-05 24.5 0.1 3.5e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 EJS42381.1 - 0.0002 21.2 0.4 0.00029 20.6 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EJS42381.1 - 0.013 15.8 0.1 0.033 14.5 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EJS42381.1 - 0.019 15.0 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 EJS42381.1 - 0.03 13.2 0.2 0.06 12.2 0.1 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EJS42381.1 - 0.07 12.0 0.3 0.2 10.5 0.2 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein WD40 PF00400.27 EJS42382.1 - 3.7e-24 83.6 23.4 0.0076 16.1 0.1 11.3 11 1 0 11 11 11 7 WD domain, G-beta repeat eIF2A PF08662.6 EJS42382.1 - 1.1e-06 28.4 0.8 0.27 10.9 0.0 3.9 3 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.1 EJS42382.1 - 0.051 12.5 0.0 1.6 7.6 0.0 3.1 2 1 2 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus UTP15_C PF09384.5 EJS42383.1 - 2.4e-52 176.5 0.2 3.9e-52 175.8 0.2 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EJS42383.1 - 8e-23 79.4 3.6 1.7e-06 27.6 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat FUR PF01475.14 EJS42384.1 - 0.012 15.5 1.4 4.5 7.2 0.0 3.1 3 0 0 3 3 3 0 Ferric uptake regulator family SOR_SNZ PF01680.12 EJS42385.1 - 6.5e-111 368.9 6.2 8.7e-111 368.4 4.3 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EJS42385.1 - 1e-07 31.2 3.9 5e-07 29.0 0.1 2.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EJS42385.1 - 0.0025 17.1 0.1 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.9 EJS42385.1 - 0.0034 16.3 1.7 0.044 12.7 0.0 2.6 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.12 EJS42385.1 - 0.013 14.3 0.6 0.74 8.5 0.0 2.7 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) FMN_dh PF01070.13 EJS42385.1 - 0.015 14.1 0.6 0.033 13.0 0.0 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase TMP-TENI PF02581.12 EJS42385.1 - 0.025 13.7 1.0 0.63 9.1 0.1 2.7 2 1 1 3 3 3 0 Thiamine monophosphate synthase/TENI NMO PF03060.10 EJS42385.1 - 0.031 13.4 0.1 0.031 13.4 0.1 2.0 2 1 0 2 2 2 0 Nitronate monooxygenase IGPS PF00218.16 EJS42385.1 - 0.032 13.2 0.1 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase 1-cysPrx_C PF10417.4 EJS42385.1 - 0.036 13.7 0.3 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin Nitr_red_bet_C PF14711.1 EJS42385.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal MMR_HSR1 PF01926.18 EJS42386.1 - 4.9e-15 55.5 0.1 2.4e-14 53.2 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EJS42386.1 - 0.00026 20.1 0.5 0.00057 19.1 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EJS42386.1 - 0.00029 20.3 0.2 0.00061 19.2 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain NTPase_1 PF03266.10 EJS42386.1 - 0.0003 20.5 0.1 0.0015 18.2 0.1 2.0 2 0 0 2 2 2 1 NTPase AAA_29 PF13555.1 EJS42386.1 - 0.0009 18.7 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EJS42386.1 - 0.0024 17.7 0.3 0.72 9.6 0.0 2.8 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 EJS42386.1 - 0.0064 15.7 0.8 0.085 12.1 0.2 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.1 EJS42386.1 - 0.0067 16.7 0.2 0.039 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EJS42386.1 - 0.0077 15.6 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EJS42386.1 - 0.01 16.6 0.4 0.25 12.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 EJS42386.1 - 0.013 14.2 0.2 0.18 10.5 0.0 2.1 1 1 1 2 2 2 0 ArgK protein AIG1 PF04548.11 EJS42386.1 - 0.015 14.3 0.1 0.26 10.3 0.0 2.3 2 0 0 2 2 2 0 AIG1 family KTI12 PF08433.5 EJS42386.1 - 0.016 14.4 0.0 0.043 13.0 0.0 1.8 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Septin PF00735.13 EJS42386.1 - 0.019 13.9 0.0 0.041 12.9 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_15 PF13175.1 EJS42386.1 - 0.021 13.8 0.2 0.021 13.8 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EJS42386.1 - 0.033 14.3 0.3 0.38 10.8 0.1 2.7 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EJS42386.1 - 0.038 13.5 0.0 0.92 9.0 0.0 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein IIGP PF05049.8 EJS42386.1 - 0.049 12.4 1.4 0.06 12.1 0.1 1.7 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_14 PF13173.1 EJS42386.1 - 0.089 12.7 0.2 0.55 10.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EJS42386.1 - 0.089 13.1 1.7 0.094 13.0 0.4 1.7 1 1 0 1 1 1 0 AAA domain Aldose_epim PF01263.15 EJS42387.1 - 7.8e-55 186.1 0.4 9.2e-55 185.8 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase zf-MYND PF01753.13 EJS42388.1 - 6.1e-09 35.6 16.0 1.6e-08 34.2 11.1 1.8 1 0 0 1 1 1 1 MYND finger DUF1154 PF06631.6 EJS42388.1 - 9.7 5.9 9.1 0.58 9.8 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Prenyltransf PF01255.14 EJS42389.1 - 4e-70 235.4 0.4 5.1e-70 235.0 0.2 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase KMP11 PF03037.11 EJS42389.1 - 0.036 14.6 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 WD40 PF00400.27 EJS42390.1 - 7.6e-29 98.5 7.3 7.6e-07 28.7 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat TF_Zn_Ribbon PF08271.7 EJS42390.1 - 0.11 11.8 1.5 0.28 10.5 1.0 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding BBS2_Mid PF14783.1 EJS42390.1 - 0.11 12.2 0.1 2.6 7.8 0.0 3.1 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PGM_PMM_I PF02878.11 EJS42391.1 - 5e-37 126.4 0.1 8.8e-37 125.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EJS42391.1 - 6.4e-26 90.6 0.0 1.1e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EJS42391.1 - 7.8e-14 51.8 0.0 2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EJS42391.1 - 1.3e-08 34.7 0.0 2.7e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.20 EJS42392.1 - 2.5e-71 239.8 1.5 2e-70 236.9 1.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42392.1 - 9.3e-42 142.8 0.7 1.1e-39 136.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 EJS42392.1 - 4.7e-20 70.7 0.0 9.2e-20 69.8 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EJS42392.1 - 1.1e-05 24.5 0.0 2.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EJS42392.1 - 0.00056 19.0 0.1 0.001 18.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS42392.1 - 0.0018 18.0 0.0 0.13 11.9 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family HLH PF00010.21 EJS42393.1 - 0.0019 17.8 0.7 0.0033 17.0 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain EPSP_synthase PF00275.15 EJS42394.1 - 1.9e-146 487.7 0.0 2.8e-146 487.2 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EJS42394.1 - 4.9e-97 323.9 0.1 8.2e-97 323.1 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EJS42394.1 - 7.6e-66 221.9 0.0 1.4e-65 221.0 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EJS42394.1 - 2.5e-37 128.1 0.1 8.9e-37 126.3 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EJS42394.1 - 9.7e-23 80.0 0.0 2.9e-22 78.4 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EJS42394.1 - 2.4e-19 69.7 0.0 8.9e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 EJS42394.1 - 4.4e-07 30.7 0.0 1.6e-06 28.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Fe-ADH_2 PF13685.1 EJS42394.1 - 6.1e-07 28.9 0.0 1.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.1 EJS42394.1 - 0.00011 22.0 0.0 0.00053 19.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EJS42394.1 - 0.0042 16.9 0.1 0.019 14.8 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EJS42394.1 - 0.027 14.7 0.0 0.21 11.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.13 EJS42394.1 - 0.052 12.6 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Zeta_toxin PF06414.7 EJS42394.1 - 0.24 10.4 0.0 0.61 9.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin BTB_2 PF02214.17 EJS42396.1 - 2.8e-08 33.8 0.1 0.00014 21.9 0.0 3.0 2 1 0 2 2 2 2 BTB/POZ domain Rgp1 PF08737.5 EJS42397.1 - 1.1e-108 364.0 9.0 1.1e-108 364.0 6.3 1.7 2 0 0 2 2 2 1 Rgp1 Methyltransf_26 PF13659.1 EJS42398.1 - 7.8e-15 54.9 0.0 1.1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EJS42398.1 - 1.5e-10 40.7 0.0 1.7e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EJS42398.1 - 1.5e-08 34.3 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EJS42398.1 - 0.0014 17.7 0.1 0.0033 16.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EJS42398.1 - 0.0035 17.7 0.0 0.02 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS42398.1 - 0.0043 17.6 0.0 0.0073 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EJS42398.1 - 0.0053 17.2 0.0 0.3 11.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EJS42398.1 - 0.025 14.1 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.1 EJS42398.1 - 0.031 14.6 0.0 0.16 12.3 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain N6-adenineMlase PF10237.4 EJS42398.1 - 0.11 12.0 0.1 0.52 9.9 0.1 2.0 1 1 0 1 1 1 0 Probable N6-adenine methyltransferase DUF3749 PF12568.3 EJS42398.1 - 0.12 11.9 0.0 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Dopey_N PF04118.9 EJS42399.1 - 4.5e-119 396.7 0.5 4.5e-119 396.7 0.4 2.7 4 0 0 4 4 4 1 Dopey, N-terminal Choline_kinase PF01633.15 EJS42400.1 - 7e-61 205.4 2.0 1.1e-60 204.8 1.4 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EJS42400.1 - 1e-13 50.4 0.1 2.4e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EJS42400.1 - 2.7e-11 43.6 0.0 1.7e-10 41.0 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EJS42400.1 - 2.2e-08 33.6 1.3 3.3e-08 33.0 0.9 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EJS42400.1 - 0.00018 20.2 0.1 0.00029 19.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) 2-oxoacid_dh PF00198.18 EJS42401.1 - 1.5e-80 269.8 0.0 2e-80 269.3 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EJS42401.1 - 4.7e-16 58.2 0.4 8.6e-16 57.3 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 EJS42401.1 - 0.0008 19.0 0.1 0.0024 17.5 0.1 1.8 1 1 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.1 EJS42401.1 - 0.0012 19.1 0.1 0.0039 17.5 0.1 1.9 1 1 1 2 2 2 1 HlyD family secretion protein HlyD PF00529.15 EJS42401.1 - 0.0018 17.6 0.2 0.024 13.9 0.1 2.2 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EJS42401.1 - 0.0018 17.8 0.2 0.053 13.2 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.1 EJS42401.1 - 0.013 15.2 0.0 0.051 13.2 0.0 2.0 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Ndc1_Nup PF09531.5 EJS42401.1 - 1 7.6 5.2 1.5 7.1 3.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.7 EJS42401.1 - 6.6 6.5 13.3 9.4 6.0 9.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF904 PF06005.7 EJS42402.1 - 0.0045 17.2 9.0 0.045 14.0 1.2 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF904) Mad3_BUB1_II PF08171.6 EJS42402.1 - 0.0081 16.0 0.4 0.0081 16.0 0.2 2.6 2 1 0 2 2 2 1 Mad3/BUB1 homology region 2 Peptidase_M20 PF01546.23 EJS42402.1 - 0.02 14.3 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 LRRC37AB_C PF14914.1 EJS42402.1 - 0.11 11.9 1.4 0.24 10.8 0.2 1.9 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain CDC37_N PF03234.9 EJS42402.1 - 0.14 12.5 5.7 0.15 12.3 1.3 2.0 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Sporozoite_P67 PF05642.6 EJS42402.1 - 0.38 8.5 1.7 0.45 8.3 0.5 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Bul1_C PF04426.7 EJS42403.1 - 0.22 10.6 3.9 0.44 9.7 0.6 2.3 2 0 0 2 2 2 0 Bul1 C terminus V_ATPase_I PF01496.14 EJS42404.1 - 0 1017.7 8.7 0 1017.5 6.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GCN5L1 PF06320.8 EJS42404.1 - 0.024 14.4 2.1 0.62 9.9 0.1 2.6 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) stn_TNFRSF12A PF12191.3 EJS42404.1 - 0.029 14.3 0.2 3.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Snapin_Pallidin PF14712.1 EJS42404.1 - 0.17 12.2 6.8 3.3 8.0 0.4 3.2 4 0 0 4 4 4 0 Snapin/Pallidin DUF4455 PF14643.1 EJS42404.1 - 0.91 8.0 5.6 0.39 9.2 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) DUF948 PF06103.6 EJS42404.1 - 2.4 8.0 7.1 5.5 6.9 0.2 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Pox_A_type_inc PF04508.7 EJS42404.1 - 3.3 7.7 5.8 14 5.7 0.3 3.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat RabGAP-TBC PF00566.13 EJS42405.1 - 7.6e-38 130.1 1.4 9.9e-38 129.7 1.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mito_carr PF00153.22 EJS42406.1 - 3.9e-69 228.4 3.4 1.8e-23 82.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cu-oxidase_2 PF07731.9 EJS42407.1 - 5.1e-47 158.8 7.1 2.8e-40 137.0 0.6 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EJS42407.1 - 6.3e-42 142.0 8.5 7.1e-39 132.1 0.6 3.9 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EJS42407.1 - 4.2e-36 124.2 10.8 3.6e-32 111.4 1.8 3.6 3 1 0 3 3 3 2 Multicopper oxidase Glycophorin_A PF01102.13 EJS42407.1 - 0.027 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A Cupredoxin_1 PF13473.1 EJS42407.1 - 0.089 12.6 0.0 12 5.8 0.0 3.4 3 0 0 3 3 3 0 Cupredoxin-like domain Tom37_C PF11801.3 EJS42408.1 - 1.4e-47 161.6 5.4 2.1e-47 161.1 3.7 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EJS42408.1 - 1.2e-23 83.1 0.0 2.4e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.1 EJS42408.1 - 0.065 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NigD PF12667.2 EJS42408.1 - 0.068 12.9 1.8 0.19 11.5 1.2 1.6 1 1 0 1 1 1 0 NigD-like protein GST_N_2 PF13409.1 EJS42408.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Suf PF05843.9 EJS42409.1 - 5.2e-72 242.9 23.5 9.3e-72 242.0 10.4 3.7 2 2 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EJS42409.1 - 0.00034 20.2 0.8 0.017 14.7 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 EJS42409.1 - 0.084 13.1 0.4 11 6.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ArgJ PF01960.13 EJS42410.1 - 1.2e-143 478.1 6.4 1.4e-143 478.0 4.4 1.0 1 0 0 1 1 1 1 ArgJ family SUR7 PF06687.7 EJS42411.1 - 1.1e-23 83.9 15.9 1.4e-23 83.6 11.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.4 EJS42411.1 - 7.3e-05 21.5 0.2 9.7e-05 21.1 0.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 EJS42411.1 - 0.019 14.3 0.6 0.041 13.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Fig1 PF12351.3 EJS42411.1 - 1.6 8.5 20.7 2.2 8.1 7.4 3.1 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Sre PF03125.13 EJS42411.1 - 2.2 7.1 8.6 0.56 9.0 0.5 2.4 2 1 0 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor TPPK_C PF12555.3 EJS42411.1 - 3.9 7.2 5.7 4.4 7.1 0.2 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal TUG-UBL1 PF11470.3 EJS42413.1 - 1.1e-17 63.6 2.0 2.3e-17 62.6 0.7 2.2 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EJS42413.1 - 1.1e-16 60.6 0.2 3.5e-16 59.0 0.1 2.0 2 0 0 2 2 2 1 UBX domain TAFII28 PF04719.9 EJS42414.1 - 3.2e-29 100.5 4.1 1.3e-28 98.6 0.7 2.8 3 0 0 3 3 3 1 hTAFII28-like protein conserved region eIF_4EBP PF05456.6 EJS42414.1 - 0.15 11.7 1.3 0.48 10.1 0.9 1.9 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PBP1_TM PF14812.1 EJS42414.1 - 0.47 10.8 10.5 2.3 8.5 0.4 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC_membrane_2 PF06472.10 EJS42414.1 - 1.6 7.7 5.6 0.12 11.4 0.1 1.8 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 Methyltransf_11 PF08241.7 EJS42415.1 - 2.2e-12 47.3 0.0 4.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EJS42415.1 - 2.2e-06 27.4 0.1 7.8e-06 25.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EJS42415.1 - 3.4e-06 27.4 0.0 6.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EJS42415.1 - 1.9e-05 24.2 0.0 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EJS42415.1 - 6.7e-05 23.1 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS42415.1 - 0.0004 20.9 0.0 0.00087 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Peroxin-22 PF12827.2 EJS42415.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family EMP24_GP25L PF01105.19 EJS42416.1 - 4.9e-42 143.7 0.0 5.7e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Rad33 PF08730.5 EJS42417.1 - 2.6e-38 131.1 3.1 1.9e-36 125.1 2.1 2.1 1 1 0 1 1 1 1 Rad33 DUF1947 PF09183.5 EJS42417.1 - 0.0085 15.8 0.1 0.65 9.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1947) Spt5-NGN PF03439.8 EJS42418.1 - 2.2e-21 75.3 0.0 6.4e-21 73.9 0.0 1.9 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EJS42418.1 - 2.6e-19 69.6 14.1 2.6e-19 69.6 9.8 3.3 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EJS42418.1 - 8.7e-15 53.7 9.1 0.00039 20.0 0.3 4.9 4 0 0 4 4 4 4 KOW motif SPT6_acidic PF14632.1 EJS42418.1 - 0.0011 19.1 19.3 0.0011 19.1 13.4 3.3 1 1 2 3 3 3 1 Acidic N-terminal SPT6 Nucleo_P87 PF07267.6 EJS42418.1 - 5.1 5.6 27.6 1.1 7.8 16.7 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_L33 PF00471.15 EJS42419.1 - 0.00014 22.0 0.1 0.00071 19.7 0.1 1.9 1 1 0 1 1 1 1 Ribosomal protein L33 Sterol_MT_C PF08498.5 EJS42420.1 - 3.2e-30 103.8 1.8 4.7e-30 103.3 1.3 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EJS42420.1 - 2.3e-20 72.8 0.0 4.8e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EJS42420.1 - 1e-16 60.9 0.0 1.7e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EJS42420.1 - 9.4e-14 51.4 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EJS42420.1 - 2.2e-12 46.6 0.2 3.1e-12 46.1 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EJS42420.1 - 4.8e-12 46.2 0.3 1.6e-11 44.5 0.0 2.0 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS42420.1 - 7.2e-12 45.8 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EJS42420.1 - 7.3e-12 45.5 0.0 1.6e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EJS42420.1 - 1e-08 34.6 0.0 1.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EJS42420.1 - 5.1e-08 32.9 0.0 1.2e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EJS42420.1 - 2.2e-07 30.5 0.6 5e-07 29.4 0.4 1.6 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EJS42420.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 EJS42420.1 - 0.0054 15.9 0.0 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EJS42420.1 - 0.0064 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain N6_N4_Mtase PF01555.13 EJS42420.1 - 0.021 14.3 0.1 5.1 6.5 0.0 2.2 2 0 0 2 2 2 0 DNA methylase DOT1 PF08123.8 EJS42420.1 - 0.024 13.9 0.1 0.062 12.5 0.0 1.8 2 0 0 2 2 2 0 Histone methylation protein DOT1 PCMT PF01135.14 EJS42420.1 - 0.032 13.7 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EJS42420.1 - 0.05 12.6 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EJS42420.1 - 0.086 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PAP1 PF08601.5 EJS42421.1 - 1.4e-76 258.4 40.8 1.4e-76 258.4 28.3 2.9 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EJS42421.1 - 1.1e-07 31.6 8.2 3e-07 30.2 5.7 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EJS42421.1 - 0.017 14.9 12.3 0.017 14.9 8.6 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Adeno_PIX PF03955.9 EJS42421.1 - 0.73 10.3 3.1 0.85 10.1 0.7 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Glyoxalase PF00903.20 EJS42423.1 - 6.4e-37 126.3 0.0 6.5e-21 74.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EJS42423.1 - 5.1e-31 107.4 0.0 2e-14 54.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EJS42423.1 - 2.4e-14 53.2 0.0 2.2e-07 30.8 0.0 3.3 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 EJS42423.1 - 4.7e-05 23.0 0.1 0.065 12.9 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_3 PF13468.1 EJS42423.1 - 0.00014 21.8 0.0 0.12 12.3 0.0 3.7 3 1 0 3 3 3 1 Glyoxalase-like domain VPS9 PF02204.13 EJS42424.1 - 5.6e-09 35.9 0.2 1.9e-08 34.2 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 EJS42424.1 - 4.3e-05 23.6 0.0 1.5 9.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EJS42424.1 - 0.00087 19.5 0.0 0.12 12.6 0.0 3.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EJS42424.1 - 0.0023 17.6 0.0 5.2 7.0 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EJS42424.1 - 0.011 16.2 1.3 39 4.9 0.0 5.0 4 2 1 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EJS42424.1 - 0.029 14.5 0.2 5.5 7.5 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Ras PF00071.17 EJS42425.1 - 1.2e-56 190.5 0.3 1.5e-56 190.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS42425.1 - 2.6e-20 73.0 0.0 5.5e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS42425.1 - 3.3e-15 55.7 0.0 3.8e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EJS42425.1 - 7.2e-09 35.1 0.1 8.7e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EJS42425.1 - 9.8e-08 31.6 0.3 3.8e-06 26.4 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EJS42425.1 - 6.4e-06 26.1 0.0 1.1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EJS42425.1 - 4.8e-05 22.6 0.1 6.5e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EJS42425.1 - 4.9e-05 23.4 0.0 8.8e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EJS42425.1 - 0.00054 19.9 0.0 0.009 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 EJS42425.1 - 0.0029 17.1 0.3 0.11 12.0 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 EJS42425.1 - 0.0033 17.1 0.1 0.0065 16.1 0.0 1.6 2 0 0 2 2 2 1 NTPase MobB PF03205.9 EJS42425.1 - 0.0036 17.0 0.2 0.0059 16.3 0.1 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EJS42425.1 - 0.0041 16.5 0.0 0.013 14.9 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EJS42425.1 - 0.0043 16.6 0.0 0.0099 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EJS42425.1 - 0.0058 16.3 0.3 0.042 13.5 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 EJS42425.1 - 0.0069 15.5 0.1 0.014 14.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 NACHT PF05729.7 EJS42425.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EJS42425.1 - 0.027 13.9 0.3 0.088 12.2 0.1 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EJS42425.1 - 0.069 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 EJS42425.1 - 0.082 12.3 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 EJS42425.1 - 0.097 11.6 0.1 0.32 9.9 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_35 PF14516.1 EJS42425.1 - 0.13 10.8 0.1 0.28 9.7 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Pkinase PF00069.20 EJS42426.1 - 1.3e-73 247.3 0.0 2.2e-73 246.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42426.1 - 3.8e-40 137.6 0.0 6.2e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EJS42426.1 - 1.5e-37 127.3 0.1 3.8e-20 71.6 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EJS42426.1 - 1.4e-07 30.8 0.0 1.5e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like SH3_3 PF08239.6 EJS42426.1 - 0.001 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Kdo PF06293.9 EJS42426.1 - 0.0062 15.6 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2076 PF09849.4 EJS42427.1 - 2.9e-07 30.8 8.2 3.6e-07 30.4 5.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EJS42427.1 - 9.7e-05 22.1 4.6 0.00015 21.5 3.2 1.3 1 0 0 1 1 1 1 CHCH domain bZIP_C PF12498.3 EJS42427.1 - 5.5 8.2 13.0 39 5.4 9.2 1.9 1 1 0 1 1 1 0 Basic leucine-zipper C terminal SAP PF02037.22 EJS42428.1 - 2.9e-12 45.7 0.5 6.5e-12 44.6 0.3 1.6 2 0 0 2 2 2 1 SAP domain PX PF00787.19 EJS42429.1 - 4.9e-22 77.8 1.4 1.2e-21 76.6 0.1 2.1 2 0 0 2 2 2 1 PX domain TAF4 PF05236.9 EJS42430.1 - 1.3e-71 240.9 3.6 2.2e-71 240.2 2.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TFIID_30kDa PF03540.8 EJS42430.1 - 0.007 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Histone PF00125.19 EJS42430.1 - 0.044 13.8 0.1 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF4590 PF15257.1 EJS42430.1 - 0.081 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) DUF2927 PF11150.3 EJS42430.1 - 0.15 11.6 1.3 0.24 11.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) PLA2_B PF01735.13 EJS42431.1 - 4e-224 744.3 4.2 4e-224 744.3 2.9 1.4 2 0 0 2 2 2 1 Lysophospholipase catalytic domain Pex14_N PF04695.8 EJS42431.1 - 0.21 11.6 6.8 0.38 10.8 4.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 EJS42431.1 - 6.2 4.9 17.6 8.8 4.4 12.2 1.1 1 0 0 1 1 1 0 Transmembrane protein PLA2_B PF01735.13 EJS42432.1 - 4.8e-230 763.8 3.8 5.9e-230 763.5 2.6 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Paxillin PF03535.8 EJS42432.1 - 0.96 9.2 7.4 0.15 11.8 0.3 2.2 2 0 0 2 2 2 0 Paxillin family ARD PF03079.9 EJS42433.1 - 8.5e-53 178.4 0.1 9.8e-53 178.2 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EJS42433.1 - 2.1e-10 39.9 0.0 3.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EJS42433.1 - 4.4e-08 32.8 0.0 7.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_8 PF13621.1 EJS42433.1 - 0.014 14.8 0.0 0.028 13.9 0.0 1.6 1 1 0 1 1 1 0 Cupin-like domain Cupin_1 PF00190.17 EJS42433.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Cupin CTP_transf_1 PF01148.15 EJS42434.1 - 4.8e-07 29.7 1.8 4.8e-07 29.7 1.2 4.1 3 1 1 4 4 4 3 Cytidylyltransferase family SEO_N PF14576.1 EJS42434.1 - 0.022 14.0 0.0 0.058 12.6 0.0 1.7 2 0 0 2 2 2 0 Sieve element occlusion N-terminus BUD22 PF09073.5 EJS42435.1 - 2.3e-98 330.1 40.9 2.3e-98 330.1 28.4 1.3 2 0 0 2 2 2 1 BUD22 YolD PF08863.5 EJS42435.1 - 0.63 9.9 7.5 0.12 12.2 2.2 2.1 2 0 0 2 2 2 0 YolD-like protein p450 PF00067.17 EJS42436.1 - 6.4e-56 189.7 0.1 8.1e-56 189.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 KilA-N PF04383.8 EJS42437.1 - 6e-05 22.6 0.1 0.00047 19.7 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Fungal_trans PF04082.13 EJS42438.1 - 6.8e-23 80.8 12.8 2.5e-22 79.0 8.9 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS42438.1 - 1e-08 34.9 15.2 1e-08 34.9 10.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.19 EJS42439.1 - 2.6e-80 270.7 0.0 3.2e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EJS42439.1 - 3.2e-13 49.5 0.3 6.6e-13 48.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EJS42439.1 - 7.9e-11 42.3 0.1 2.9e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EJS42439.1 - 6.5e-07 28.5 0.0 0.00011 21.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EJS42439.1 - 2.9e-06 26.4 1.8 3.9e-06 25.9 1.3 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EJS42439.1 - 4.7e-05 22.6 0.3 7e-05 22.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EJS42439.1 - 0.00046 19.3 0.2 0.00078 18.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EJS42439.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EJS42439.1 - 0.0014 17.1 1.9 0.018 13.5 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EJS42439.1 - 0.002 17.0 1.9 0.0081 15.0 0.5 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EJS42439.1 - 0.005 17.2 2.5 0.0086 16.4 0.4 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EJS42439.1 - 0.0053 15.7 0.4 2.2 7.1 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 EJS42439.1 - 0.0086 15.8 0.5 2.7 7.7 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EJS42439.1 - 0.013 15.5 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EJS42439.1 - 0.024 14.2 0.3 0.047 13.2 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 EJS42439.1 - 0.043 12.8 0.1 0.068 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pdase_C33_assoc PF14756.1 EJS42439.1 - 0.12 12.0 0.1 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Peptidase_C33-associated domain Copper-fist PF00649.13 EJS42440.1 - 1.9e-21 74.9 4.8 6.6e-21 73.2 3.4 2.0 1 0 0 1 1 1 1 Copper fist DNA binding domain UQ_con PF00179.21 EJS42441.1 - 1.6e-49 166.9 0.0 1.8e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EJS42441.1 - 0.046 13.6 2.4 0.12 12.3 1.7 2.0 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 EJS42441.1 - 0.085 12.6 0.2 0.18 11.5 0.1 1.7 2 1 0 2 2 2 0 Prokaryotic E2 family B TrmE_N PF10396.4 EJS42442.1 - 1.9e-33 114.8 0.0 2.8e-32 111.0 0.0 2.4 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EJS42442.1 - 2.1e-23 82.5 0.7 4.3e-23 81.4 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 EJS42442.1 - 1.4e-16 60.6 0.0 4.7e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 EJS42442.1 - 3e-15 55.8 0.4 6.3e-15 54.7 0.3 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EJS42442.1 - 1.1e-08 34.8 0.3 2.2e-07 30.5 0.1 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 EJS42442.1 - 3.3e-08 33.0 0.0 5.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS42442.1 - 9e-07 29.4 1.6 1.5e-06 28.7 0.1 2.2 3 0 0 3 3 3 1 Miro-like protein Arf PF00025.16 EJS42442.1 - 8.1e-06 25.1 0.4 4.8e-05 22.6 0.3 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 EJS42442.1 - 4.9e-05 22.8 0.0 0.0041 16.6 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EJS42442.1 - 0.00049 19.3 0.1 0.0035 16.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EJS42442.1 - 0.005 16.6 0.5 0.024 14.4 0.1 2.3 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 EJS42442.1 - 0.03 13.4 1.3 0.24 10.4 0.1 2.4 2 0 0 2 2 2 0 AIG1 family AAA_28 PF13521.1 EJS42442.1 - 0.045 13.7 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Tape_meas_lam_C PF09718.5 EJS42442.1 - 0.1 12.5 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Pex2_Pex12 PF04757.9 EJS42444.1 - 7.1e-43 146.6 13.7 8.7e-43 146.3 9.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EJS42444.1 - 6.6e-05 22.8 5.5 0.00012 22.0 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EJS42444.1 - 0.00017 21.1 3.1 0.0003 20.4 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EJS42444.1 - 0.0071 16.2 7.4 0.013 15.3 5.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING UPF0546 PF10639.4 EJS42444.1 - 0.055 13.2 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 zf-RING_2 PF13639.1 EJS42444.1 - 0.11 12.3 4.5 0.21 11.4 3.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EJS42444.1 - 0.23 11.1 5.0 0.41 10.3 3.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TAP42 PF04177.7 EJS42445.1 - 3.9e-96 321.9 17.6 4.4e-96 321.7 12.2 1.0 1 0 0 1 1 1 1 TAP42-like family DUF3812 PF12757.2 EJS42446.1 - 3.6e-33 114.2 1.1 3.6e-33 114.2 0.8 5.4 6 0 0 6 6 6 1 Protein of unknown function (DUF3812) FCH PF00611.18 EJS42447.1 - 6.3e-20 71.1 0.0 6.3e-20 71.1 0.0 3.4 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EJS42447.1 - 0.00059 19.1 0.0 0.0017 17.7 0.0 1.8 1 0 0 1 1 1 1 SH3 domain Peptidase_S24 PF00717.18 EJS42448.1 - 4.5e-08 32.6 0.0 1.2e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EJS42448.1 - 0.00043 19.8 0.0 0.0018 17.7 0.0 1.9 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Rhodanese PF00581.15 EJS42449.1 - 3.8e-10 40.1 0.0 9.9e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zf-C2H2 PF00096.21 EJS42450.1 - 5.4e-12 45.3 18.1 3.4e-06 27.0 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS42450.1 - 1.6e-09 37.4 16.8 0.00026 21.0 1.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EJS42450.1 - 4.8e-08 32.9 20.7 5.3e-06 26.4 2.4 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EJS42450.1 - 9.5e-06 25.6 15.2 0.0036 17.3 3.4 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EJS42450.1 - 7.8e-05 22.7 12.0 0.041 14.0 1.7 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EJS42450.1 - 0.0028 17.4 8.8 0.014 15.2 1.4 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger GAGA PF09237.6 EJS42450.1 - 0.0092 15.5 2.7 1.1 8.9 0.3 2.6 1 1 1 2 2 2 2 GAGA factor zf-BED PF02892.10 EJS42450.1 - 0.018 14.7 16.6 0.37 10.5 1.4 4.2 3 0 0 3 3 3 0 BED zinc finger zf-Di19 PF05605.7 EJS42450.1 - 0.095 12.8 8.6 0.22 11.6 6.0 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 EJS42450.1 - 1.2 7.5 11.3 0.8 8.1 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF629) HMA PF00403.21 EJS42451.1 - 3.9e-11 42.9 0.1 2.3e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain Sod_Cu PF00080.15 EJS42451.1 - 1.2e-08 35.1 0.1 2.6e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PC4 PF02229.11 EJS42452.1 - 1.2e-20 72.4 0.1 2.3e-20 71.5 0.1 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF966 PF06136.8 EJS42452.1 - 0.56 9.5 15.0 0.69 9.2 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PLRV_ORF5 PF01690.12 EJS42452.1 - 7.1 5.6 25.2 9.6 5.2 17.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SRF-TF PF00319.13 EJS42453.1 - 3.3e-25 87.0 0.3 4.6e-25 86.5 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) RXT2_N PF08595.6 EJS42453.1 - 0.17 11.6 12.0 0.42 10.4 2.0 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Prothymosin PF03247.9 EJS42453.1 - 0.81 9.8 23.1 0.42 10.7 8.8 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family FAM176 PF14851.1 EJS42453.1 - 1.5 8.4 15.6 0.12 12.0 0.5 2.3 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 EJS42453.1 - 1.7 8.1 17.9 0.27 10.7 8.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 EJS42453.1 - 1.7 9.0 23.0 0.2 12.0 6.3 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SDA1 PF05285.7 EJS42453.1 - 3.5 6.8 20.1 6.1 6.0 13.9 1.4 1 0 0 1 1 1 0 SDA1 DUF4199 PF13858.1 EJS42453.1 - 5.1 6.9 6.6 52 3.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) GOLD_2 PF13897.1 EJS42453.1 - 7.5 6.7 12.3 2.4 8.3 1.6 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF605 PF04652.11 EJS42453.1 - 8.9 5.5 47.6 12 5.2 33.0 1.1 1 0 0 1 1 1 0 Vta1 like PWWP PF00855.12 EJS42454.1 - 2.4e-17 62.8 1.9 2.4e-17 62.8 1.3 2.6 2 1 0 2 2 2 1 PWWP domain BTV_NS2 PF04514.7 EJS42454.1 - 2.7 6.8 21.5 5.7 5.7 9.5 2.4 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Swi3 PF07962.7 EJS42455.1 - 1.1e-28 98.7 0.3 3e-28 97.2 0.0 1.9 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 BOP1NT PF08145.7 EJS42456.1 - 5e-103 344.3 7.6 9.7e-103 343.4 5.3 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EJS42456.1 - 2.1e-28 97.1 8.8 3.9e-11 42.3 0.2 7.6 7 1 0 7 7 7 4 WD domain, G-beta repeat Colicin_D PF11429.3 EJS42456.1 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Colicin D eIF-3c_N PF05470.7 EJS42456.1 - 0.14 10.2 6.3 84 1.0 8.8 2.1 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TPT PF03151.11 EJS42457.1 - 6.4e-47 159.0 2.3 6.4e-47 159.0 1.6 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EJS42457.1 - 5.2e-11 42.0 3.4 5.2e-11 42.0 2.4 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EJS42457.1 - 1e-09 38.4 23.3 1.1e-05 25.5 5.8 2.7 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EJS42457.1 - 3.5e-09 36.1 1.1 0.00014 21.0 1.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EJS42457.1 - 4.2e-06 26.9 5.4 4.2e-06 26.9 3.8 3.0 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EJS42457.1 - 7.6e-06 24.9 2.2 7.6e-06 24.9 1.6 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UPF0546 PF10639.4 EJS42457.1 - 0.0052 16.5 10.3 0.29 10.9 0.8 2.9 3 0 0 3 3 3 2 Uncharacterised protein family UPF0546 A_deaminase PF00962.17 EJS42458.1 - 5.4e-122 406.8 0.1 7.6e-122 406.3 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase ubiquitin PF00240.18 EJS42459.1 - 0.00015 21.0 0.1 0.001 18.3 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EJS42459.1 - 0.0012 18.4 0.0 0.0082 15.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EJS42459.1 - 0.0018 18.1 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EJS42459.1 - 0.0054 16.8 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain AhpC-TSA PF00578.16 EJS42460.1 - 2.5e-37 127.3 0.1 6.4e-36 122.7 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EJS42460.1 - 5.7e-20 71.3 0.0 1e-19 70.5 0.0 1.4 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.4 EJS42460.1 - 2.7e-10 39.7 0.3 5.5e-10 38.7 0.2 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Homeobox PF00046.24 EJS42461.1 - 5.2e-17 61.2 2.4 1.1e-16 60.1 1.7 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EJS42461.1 - 0.00034 20.2 0.3 0.0022 17.6 0.0 2.4 2 0 0 2 2 2 1 Homeobox KN domain Pribosyltran PF00156.22 EJS42462.1 - 2.1e-15 56.5 0.0 3e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EJS42462.1 - 0.029 13.5 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Abhydrolase_5 PF12695.2 EJS42463.1 - 0.092 12.4 0.0 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family OST3_OST6 PF04756.8 EJS42464.1 - 7.8e-35 119.7 12.2 1.2e-34 119.2 8.4 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin_6 PF13848.1 EJS42464.1 - 0.0053 16.5 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 EJS42464.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin EamA PF00892.15 EJS42465.1 - 3.5e-08 33.5 29.8 3e-05 24.0 3.0 3.4 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 EJS42465.1 - 2.2e-07 30.6 21.7 3.3e-05 23.5 4.8 3.1 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 EJS42465.1 - 3.2e-07 29.5 6.6 3.2e-07 29.5 4.6 1.6 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 EJS42465.1 - 0.00019 21.5 0.8 0.00019 21.5 0.5 3.6 3 1 0 4 4 4 2 Multidrug resistance efflux transporter SUR7 PF06687.7 EJS42467.1 - 1.8e-37 128.9 9.4 2.4e-37 128.5 6.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EJS42467.1 - 1.7e-07 31.2 4.2 3.3e-07 30.3 2.9 1.4 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF805 PF05656.9 EJS42467.1 - 2.5 7.9 11.3 0.5 10.2 4.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) GFO_IDH_MocA PF01408.17 EJS42468.1 - 1.9e-07 31.6 0.0 2.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EJS42468.1 - 0.0075 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Suc_Fer-like PF06999.7 EJS42469.1 - 6.9e-30 104.7 0.0 8.4e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Gsf2 PF11055.3 EJS42470.1 - 4.7e-181 601.3 0.1 5.5e-181 601.0 0.1 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 Kin17_mid PF10357.4 EJS42471.1 - 0.0002 20.9 2.3 0.00069 19.2 0.5 2.6 2 1 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein Suf PF05843.9 EJS42471.1 - 0.013 15.2 0.5 0.013 15.2 0.3 2.6 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) RNA_pol_I_TF PF04090.7 EJS42472.1 - 5.7e-76 254.2 2.4 1.3e-75 253.0 1.7 1.7 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor Carn_acyltransf PF00755.15 EJS42473.1 - 2e-192 640.4 0.3 2.4e-192 640.1 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-HIT PF04438.11 EJS42474.1 - 0.0081 15.7 10.0 0.015 14.9 7.0 1.4 1 0 0 1 1 1 1 HIT zinc finger ADH_zinc_N PF00107.21 EJS42475.1 - 6.1e-18 64.6 0.8 1.1e-17 63.8 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LAB_N PF07578.6 EJS42475.1 - 0.033 14.0 0.1 0.083 12.8 0.1 1.6 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain ERO1 PF04137.10 EJS42476.1 - 3.5e-120 401.2 2.2 3.5e-120 401.2 1.5 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) COX14 PF14880.1 EJS42477.1 - 1.2e-24 85.6 1.9 1.4e-24 85.4 1.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF533 PF04391.7 EJS42477.1 - 0.086 12.1 0.1 0.088 12.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Ish1 PF10281.4 EJS42478.1 - 1.3e-45 153.0 50.4 1e-12 47.8 0.2 7.8 7 0 0 7 7 7 6 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EJS42478.1 - 6.1e-05 22.4 0.1 6.6 6.3 0.0 5.8 6 1 0 6 6 6 1 SAP domain MscS_porin PF12795.2 EJS42478.1 - 0.0015 17.9 0.3 0.0015 17.9 0.2 2.8 2 1 0 2 2 2 1 Mechanosensitive ion channel porin domain ICEA PF05315.6 EJS42478.1 - 0.0061 15.8 3.8 0.0067 15.7 0.3 2.7 3 0 0 3 3 3 1 ICEA Protein DUF4286 PF14114.1 EJS42478.1 - 0.017 15.3 5.7 4.6 7.5 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4286) DegS PF05384.6 EJS42478.1 - 0.052 12.7 4.8 1.1 8.4 0.1 3.3 2 1 1 3 3 3 0 Sensor protein DegS HeH PF12949.2 EJS42478.1 - 0.097 12.2 3.1 33 4.1 0.0 4.1 4 0 0 4 4 4 0 HeH/LEM domain NYD-SP28 PF14772.1 EJS42478.1 - 0.36 10.9 10.4 1.9 8.6 0.5 3.5 3 1 1 4 4 4 0 Sperm tail SAM_2 PF07647.12 EJS42478.1 - 0.41 10.5 16.1 18 5.2 0.0 6.2 7 0 0 7 7 7 0 SAM domain (Sterile alpha motif) FAD_binding_6 PF00970.19 EJS42480.1 - 1.3e-28 99.0 0.0 7.2e-28 96.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EJS42480.1 - 8.9e-24 84.1 0.0 1.4e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EJS42480.1 - 0.00029 20.7 0.0 0.0019 18.1 0.0 2.0 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Sugar_tr PF00083.19 EJS42481.1 - 1.7e-49 168.6 11.5 2.2e-49 168.2 7.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS42481.1 - 3.3e-27 95.1 14.3 4.4e-22 78.2 5.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Gtr1_RagA PF04670.7 EJS42482.1 - 2.8e-94 314.5 1.2 3.6e-94 314.2 0.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EJS42482.1 - 1.3e-09 37.6 0.3 5.6e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EJS42482.1 - 2.3e-08 34.5 0.1 5.2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS42482.1 - 8.9e-08 31.5 0.1 1.8e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EJS42482.1 - 3e-06 27.1 0.0 9.5e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EJS42482.1 - 0.004 16.6 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EJS42482.1 - 0.0073 16.6 0.1 0.017 15.4 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EJS42482.1 - 0.013 14.9 0.2 0.026 14.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.11 EJS42482.1 - 0.03 13.4 0.6 0.31 10.1 0.1 2.4 1 1 0 2 2 2 0 AIG1 family DUF815 PF05673.8 EJS42482.1 - 0.038 12.9 0.0 0.08 11.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 EJS42482.1 - 0.062 12.7 0.2 0.12 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA-like domain Guanylate_kin PF00625.16 EJS42482.1 - 0.07 12.5 1.5 0.72 9.2 0.4 2.7 2 1 0 2 2 2 0 Guanylate kinase Pyr_redox_2 PF07992.9 EJS42483.1 - 2.7e-29 102.5 1.1 2.8e-17 63.2 0.0 4.2 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EJS42483.1 - 2.6e-13 50.1 0.1 2.1e-11 44.0 0.2 3.0 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EJS42483.1 - 2.6e-09 37.4 0.0 0.00053 20.1 0.0 3.2 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EJS42483.1 - 0.089 11.2 0.0 11 4.4 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein Methyltransf_28 PF02636.12 EJS42483.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Anp1 PF03452.9 EJS42484.1 - 8.6e-126 418.5 0.0 1.3e-125 418.0 0.0 1.2 1 0 0 1 1 1 1 Anp1 DUF866 PF05907.8 EJS42484.1 - 0.14 11.6 0.3 0.25 10.8 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) TAF8_C PF10406.4 EJS42485.1 - 1.4e-20 73.1 0.2 1.4e-20 73.1 0.1 2.5 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term CHB_HEX_C PF03174.8 EJS42486.1 - 0.0046 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain DUF2360 PF10152.4 EJS42486.1 - 1.7 8.9 6.9 0.89 9.8 2.0 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Mito_fiss_reg PF05308.6 EJS42486.1 - 1.7 7.9 11.0 0.43 9.9 3.4 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator CTK3_C PF12350.3 EJS42487.1 - 1.3e-22 79.5 0.2 3.2e-22 78.3 0.2 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.3 EJS42487.1 - 0.00019 21.0 3.1 0.24 11.0 0.1 3.0 3 0 0 3 3 3 2 CTD kinase subunit gamma CTK3 Bul1_N PF04425.7 EJS42488.1 - 2.6e-163 543.7 6.5 3e-163 543.4 3.3 2.0 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.7 EJS42488.1 - 5.5e-112 373.4 11.1 5.5e-112 373.4 7.7 2.3 2 0 0 2 2 2 1 Bul1 C terminus Ubie_methyltran PF01209.13 EJS42489.1 - 4.9e-105 349.8 0.1 5.6e-105 349.6 0.1 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EJS42489.1 - 1.3e-11 44.3 0.0 2.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EJS42489.1 - 1e-07 32.3 0.0 1.8e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EJS42489.1 - 3e-07 30.8 0.0 5.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EJS42489.1 - 1e-06 29.0 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS42489.1 - 3.7e-05 24.2 0.0 6.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EJS42489.1 - 0.00015 21.5 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EJS42489.1 - 0.019 14.5 0.0 0.22 11.1 0.0 2.2 1 1 1 2 2 2 0 Hypothetical methyltransferase Methyltransf_26 PF13659.1 EJS42489.1 - 0.13 12.2 0.0 1.3 9.1 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain DUF1892 PF08987.5 EJS42490.1 - 1.6e-43 147.3 6.4 1.7e-43 147.2 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) zf-C3HC PF07967.8 EJS42491.1 - 4.9e-12 45.7 4.7 2.2e-10 40.4 1.6 2.5 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EJS42491.1 - 6.4e-05 22.7 3.7 0.0052 16.5 0.6 2.5 2 0 0 2 2 2 2 Rsm1-like Eapp_C PF10238.4 EJS42491.1 - 0.75 9.7 8.0 4.7 7.1 3.2 2.4 1 1 1 2 2 2 0 E2F-associated phosphoprotein Pribosyltran PF00156.22 EJS42492.1 - 2.1e-17 63.0 0.3 4.1e-17 62.0 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SRP19 PF01922.12 EJS42493.1 - 1.4e-28 99.2 0.0 3.2e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 SRP19 protein Nup188 PF10487.4 EJS42494.1 - 0 1057.6 60.4 0 1057.6 41.8 2.0 3 0 0 3 3 3 1 Nucleoporin subcomplex protein binding to Pom34 CUE PF02845.11 EJS42495.1 - 1.7e-07 30.6 0.0 2.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 CUE domain TMEM154 PF15102.1 EJS42495.1 - 0.0079 15.9 2.1 0.38 10.4 0.2 2.2 1 1 1 2 2 2 2 TMEM154 protein family COX2_TM PF02790.10 EJS42495.1 - 0.023 14.6 0.0 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF4245 PF14030.1 EJS42495.1 - 0.055 13.2 0.2 0.063 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Shisa PF13908.1 EJS42495.1 - 0.064 13.4 3.6 0.078 13.1 2.5 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3484 PF11983.3 EJS42495.1 - 5.4 7.9 8.0 12 6.7 5.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) Glyco_transf_20 PF00982.16 EJS42496.1 - 4.5e-171 569.4 0.4 6.7e-171 568.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EJS42496.1 - 9.4e-51 171.9 0.0 2e-50 170.9 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Fungal_trans_2 PF11951.3 EJS42497.1 - 4.1e-111 371.2 1.4 5.6e-111 370.8 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS42497.1 - 7.7e-13 48.1 7.4 2.1e-12 46.7 5.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2363 PF10155.4 EJS42497.1 - 0.0025 17.7 1.8 0.88 9.5 0.1 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2363) TFIID-18kDa PF02269.11 EJS42498.1 - 2.6e-36 123.3 0.0 3.8e-36 122.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EJS42498.1 - 0.0053 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EJS42498.1 - 0.033 14.1 0.0 0.078 12.9 0.0 1.7 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) CDC45 PF02724.9 EJS42498.1 - 0.24 9.3 3.6 0.21 9.6 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein VPS9 PF02204.13 EJS42499.1 - 1.9e-31 108.1 0.1 5e-31 106.7 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EJS42499.1 - 1.6e-11 43.4 0.0 2.9e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain Rad10 PF03834.9 EJS42500.1 - 3.1e-26 90.8 1.8 3.1e-26 90.8 1.3 1.6 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) TraG_N PF07916.6 EJS42500.1 - 0.004 15.6 0.6 0.0055 15.1 0.4 1.1 1 0 0 1 1 1 1 TraG-like protein, N-terminal region Utp14 PF04615.8 EJS42501.1 - 4.6e-218 726.0 87.6 4.6e-218 726.0 60.7 2.0 1 1 1 2 2 2 1 Utp14 protein Proteasome PF00227.21 EJS42502.1 - 2.3e-58 196.6 0.0 2.9e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EJS42502.1 - 3.8e-09 35.7 0.8 7e-09 34.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD_binding_6 PF00970.19 EJS42503.1 - 7.9e-28 96.4 0.0 1.2e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EJS42503.1 - 2.6e-23 82.6 0.0 3.9e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EJS42503.1 - 1.2e-05 25.2 0.0 0.00095 19.0 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Cys_Met_Meta_PP PF01053.15 EJS42505.1 - 1.1e-22 79.9 0.0 2.5e-22 78.7 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ATP-synt_J PF04911.7 EJS42506.1 - 1.1e-28 98.4 0.8 1.2e-28 98.3 0.6 1.0 1 0 0 1 1 1 1 ATP synthase j chain zf-C2H2 PF00096.21 EJS42507.1 - 2.6e-06 27.4 15.4 0.00036 20.7 2.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EJS42507.1 - 1.6e-05 24.9 9.8 5.8e-05 23.1 3.1 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EJS42507.1 - 0.0053 16.9 15.7 0.038 14.3 2.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Dus PF01207.12 EJS42508.1 - 1e-87 293.8 0.0 1.3e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF4085 PF13315.1 EJS42508.1 - 0.0021 17.4 0.7 0.0035 16.7 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4085) Cupin_5 PF06172.6 EJS42509.1 - 1.3e-39 135.3 0.0 1.5e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Pro_isomerase PF00160.16 EJS42510.1 - 7.4e-48 162.6 0.1 9.2e-48 162.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sybindin PF04099.7 EJS42511.1 - 7.9e-20 71.0 0.3 9.9e-20 70.6 0.2 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EJS42511.1 - 0.003 17.4 0.1 0.0036 17.1 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region OstA_C PF04453.9 EJS42511.1 - 0.0032 16.6 0.2 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 Organic solvent tolerance protein HMG-CoA_red PF00368.13 EJS42513.1 - 1.6e-159 530.5 0.9 1.6e-159 530.5 0.6 1.4 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EJS42513.1 - 3.3e-45 153.4 1.2 3.3e-45 153.4 0.8 1.9 2 0 0 2 2 2 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EJS42513.1 - 3.6e-07 29.7 5.7 3.6e-07 29.7 3.9 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation SR-25 PF10500.4 EJS42513.1 - 0.048 13.1 4.8 0.076 12.4 3.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FKBP_C PF00254.23 EJS42514.1 - 5.5e-29 100.0 0.0 2.6e-27 94.6 0.0 2.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4045 PF13254.1 EJS42514.1 - 1.5 8.0 21.7 1.2 8.3 6.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) TFIIF_alpha PF05793.7 EJS42514.1 - 2.9 6.1 68.9 2.7 6.2 16.6 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.7 EJS42514.1 - 3.4 7.4 36.8 0.89 9.3 5.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MIP-T3 PF10243.4 EJS42514.1 - 5.6 5.3 47.1 2.9 6.2 21.4 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Spore_coat_CotO PF14153.1 EJS42514.1 - 8.4 5.7 32.5 6.7 6.1 5.1 2.4 2 0 0 2 2 2 0 Spore coat protein CotO GAGA_bind PF06217.7 EJS42514.1 - 9.1 6.1 21.6 11 5.8 9.2 2.4 2 0 0 2 2 2 0 GAGA binding protein-like family C2 PF00168.25 EJS42515.1 - 6.4e-47 157.3 2.3 1e-17 63.7 0.1 5.7 5 0 0 5 5 5 5 C2 domain HemX PF04375.9 EJS42515.1 - 0.43 9.1 6.5 0.072 11.6 1.2 1.9 2 0 0 2 2 2 0 HemX Dor1 PF04124.7 EJS42516.1 - 6.7e-72 241.7 6.6 3.7e-71 239.3 3.8 2.0 2 0 0 2 2 2 1 Dor1-like family Hid1 PF12722.2 EJS42516.1 - 0.0062 14.2 16.4 0.0012 16.6 8.8 1.5 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Corona_nucleoca PF00937.13 EJS42516.1 - 9.2 5.1 15.4 17 4.2 10.7 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Dak1 PF02733.12 EJS42517.1 - 1.5e-141 470.7 1.4 1.9e-141 470.3 1.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EJS42517.1 - 5.9e-45 153.0 2.1 7.6e-45 152.7 0.6 1.8 2 0 0 2 2 2 1 DAK2 domain SSrecog PF03531.9 EJS42518.1 - 3.3e-70 235.8 4.0 6e-41 140.1 0.1 2.8 2 1 1 3 3 3 2 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EJS42518.1 - 5.4e-30 103.2 0.3 6.3e-27 93.4 0.1 3.1 3 0 0 3 3 3 2 Histone chaperone Rttp106-like DUF3678 PF12435.3 EJS42518.1 - 0.13 11.8 0.6 9.2 5.9 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) IBR PF01485.16 EJS42519.1 - 1.1e-14 54.0 27.2 6.6e-10 38.7 1.5 4.5 4 1 0 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EJS42519.1 - 0.00017 21.3 8.9 0.00017 21.3 6.2 4.8 4 2 1 5 5 5 2 Ring finger domain zf-C3HC4_2 PF13923.1 EJS42519.1 - 0.019 15.0 10.6 0.019 15.0 7.4 5.4 5 1 1 6 6 6 0 Zinc finger, C3HC4 type (RING finger) BAH PF01426.13 EJS42521.1 - 6.3e-20 71.1 0.1 1.8e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 BAH domain AAA PF00004.24 EJS42521.1 - 1.2e-18 67.5 0.0 4.2e-18 65.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EJS42521.1 - 3.2e-07 30.5 0.1 2.4e-06 27.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EJS42521.1 - 6.6e-06 26.2 0.0 0.00031 20.7 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 EJS42521.1 - 0.0015 18.2 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EJS42521.1 - 0.0027 18.5 3.6 0.007 17.1 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EJS42521.1 - 0.0036 17.5 0.0 0.0036 17.5 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EJS42521.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Bd3614_N PF14442.1 EJS42521.1 - 0.21 11.5 7.7 0.57 10.1 5.4 1.7 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Nop14 PF04147.7 EJS42521.1 - 0.22 9.4 32.0 0.14 10.0 17.6 2.2 2 0 0 2 2 2 0 Nop14-like family Daxx PF03344.10 EJS42521.1 - 2.2 6.6 31.7 0.03 12.8 15.3 2.0 2 0 0 2 2 2 0 Daxx Family TFIIF_alpha PF05793.7 EJS42521.1 - 5.5 5.2 38.1 0.078 11.3 18.7 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 EJS42521.1 - 8.2 4.3 24.1 0.43 8.5 10.1 2.2 2 0 0 2 2 2 0 CDC45-like protein Ras PF00071.17 EJS42522.1 - 5e-30 104.0 0.1 6.2e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS42522.1 - 1.3e-17 64.3 0.1 6.5e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EJS42522.1 - 1.4e-06 27.6 0.1 1.8e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EJS42522.1 - 1.6e-05 24.3 0.0 0.00013 21.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EJS42522.1 - 5.6e-05 22.4 0.1 7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EJS42522.1 - 0.029 14.3 0.1 0.045 13.6 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 EJS42522.1 - 0.11 12.2 0.3 0.27 10.9 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_S3Ae PF01015.13 EJS42523.1 - 7.2e-80 266.9 6.8 8.5e-80 266.6 4.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EJS42523.1 - 0.048 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region HhH-GPD PF00730.20 EJS42524.1 - 6.8e-22 77.8 0.1 1.8e-21 76.4 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.7 EJS42524.1 - 3.5e-20 72.1 0.2 6.9e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain cNMP_binding PF00027.24 EJS42525.1 - 4.1e-44 148.3 0.1 1.1e-20 73.2 0.0 4.6 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EJS42525.1 - 6.1e-19 68.7 5.5 7.5e-13 48.8 0.4 3.9 5 0 0 5 5 5 2 Patatin-like phospholipase RNR_inhib PF08591.5 EJS42526.1 - 0.00079 20.2 1.0 0.001 19.8 0.7 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Mst1_SARAH PF11629.3 EJS42526.1 - 0.063 13.1 0.3 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 SPC25 PF06703.6 EJS42527.1 - 1.6e-42 144.8 1.1 1.8e-42 144.6 0.8 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Pkinase PF00069.20 EJS42528.1 - 5e-58 196.2 0.0 8.9e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42528.1 - 1.5e-21 76.6 0.0 5.8e-20 71.4 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS42528.1 - 9.6e-05 21.4 0.0 0.1 11.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EJS42528.1 - 0.0007 18.7 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EJS42528.1 - 0.075 12.3 0.2 0.22 10.8 0.1 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL ABC_tran PF00005.22 EJS42529.1 - 6.7e-43 146.2 0.4 3.4e-21 75.9 0.0 4.8 4 2 0 4 4 2 2 ABC transporter AAA_21 PF13304.1 EJS42529.1 - 1.8e-17 64.2 0.1 0.0012 18.9 0.0 4.4 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EJS42529.1 - 7.8e-16 57.9 0.1 3.5e-06 26.4 0.0 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EJS42529.1 - 3.7e-09 37.1 3.6 0.0032 17.8 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EJS42529.1 - 1.1e-08 35.8 0.0 0.0054 17.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EJS42529.1 - 1.1e-08 35.2 0.0 0.00033 20.8 0.0 3.6 4 1 0 4 4 2 2 AAA domain DUF258 PF03193.11 EJS42529.1 - 2.7e-08 33.1 0.0 0.00021 20.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EJS42529.1 - 2.8e-08 33.1 0.0 0.0055 16.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 EJS42529.1 - 6.7e-08 32.6 0.0 0.0092 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EJS42529.1 - 9.1e-07 29.4 0.0 0.024 15.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EJS42529.1 - 1e-06 28.6 0.0 0.0064 16.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 EJS42529.1 - 1.3e-06 28.6 0.0 0.11 12.6 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EJS42529.1 - 1.5e-06 28.2 0.0 0.1 12.7 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 EJS42529.1 - 4e-06 26.6 0.0 0.087 12.5 0.0 3.1 3 0 0 3 3 2 2 Archaeal ATPase AAA_18 PF13238.1 EJS42529.1 - 4.4e-06 27.0 0.1 0.022 15.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 EJS42529.1 - 4.7e-06 26.4 0.1 0.017 14.9 0.0 3.4 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EJS42529.1 - 4.8e-06 25.5 0.1 0.075 11.7 0.0 2.5 2 0 0 2 2 2 2 ArgK protein Dynamin_N PF00350.18 EJS42529.1 - 7.5e-06 25.8 0.0 0.00018 21.4 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 EJS42529.1 - 1.2e-05 24.9 0.0 0.24 10.8 0.0 3.2 4 0 0 4 4 4 2 AAA-like domain AAA_14 PF13173.1 EJS42529.1 - 2e-05 24.4 0.0 0.21 11.5 0.0 3.8 4 0 0 4 4 3 1 AAA domain ParcG PF10274.4 EJS42529.1 - 2.4e-05 24.3 0.6 0.43 10.4 0.0 3.2 2 1 1 3 3 3 1 Parkin co-regulated protein AAA_16 PF13191.1 EJS42529.1 - 2.4e-05 24.3 0.3 0.44 10.5 0.0 4.1 5 0 0 5 5 4 1 AAA ATPase domain AAA_33 PF13671.1 EJS42529.1 - 2.5e-05 24.1 0.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EJS42529.1 - 4.4e-05 23.1 0.0 0.44 10.2 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MutS_V PF00488.16 EJS42529.1 - 7.9e-05 22.1 0.0 0.14 11.5 0.0 2.4 2 0 0 2 2 2 2 MutS domain V NACHT PF05729.7 EJS42529.1 - 0.0001 22.0 0.0 0.049 13.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain HEAT_2 PF13646.1 EJS42529.1 - 0.00018 21.7 0.0 0.028 14.6 0.0 3.1 2 1 0 2 2 2 1 HEAT repeats DUF87 PF01935.12 EJS42529.1 - 0.00028 20.7 1.4 0.34 10.6 0.0 4.1 5 0 0 5 5 3 1 Domain of unknown function DUF87 Rad17 PF03215.10 EJS42529.1 - 0.00042 19.1 0.2 0.23 10.1 0.0 2.5 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein PduV-EutP PF10662.4 EJS42529.1 - 0.00056 19.4 0.0 0.36 10.3 0.0 3.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Adeno_IVa2 PF02456.10 EJS42529.1 - 0.0022 16.6 0.0 0.5 8.9 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein UME PF08064.8 EJS42529.1 - 0.0025 17.7 1.3 0.036 14.0 0.3 2.7 2 1 1 3 3 2 1 UME (NUC010) domain AAA_13 PF13166.1 EJS42529.1 - 0.0041 15.6 11.3 1.1 7.5 0.0 4.4 4 1 1 5 5 5 2 AAA domain Vac14_Fab1_bd PF12755.2 EJS42529.1 - 0.0083 16.4 0.6 6.4 7.2 0.0 3.8 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region AAA_30 PF13604.1 EJS42529.1 - 0.018 14.5 0.1 12 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EJS42529.1 - 0.019 14.3 0.0 9.2 5.6 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 EJS42529.1 - 0.019 14.0 0.2 0.77 8.8 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 EJS42529.1 - 0.022 14.2 0.0 2.9 7.3 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain HEAT PF02985.17 EJS42529.1 - 0.023 14.7 0.2 38 4.7 0.0 4.2 4 0 0 4 4 3 0 HEAT repeat NTPase_1 PF03266.10 EJS42529.1 - 0.027 14.1 0.1 6.7 6.3 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.1 EJS42529.1 - 0.037 13.4 0.0 6.3 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain HEAT_EZ PF13513.1 EJS42529.1 - 0.047 14.1 3.5 16 6.1 0.1 5.3 5 1 1 6 6 5 0 HEAT-like repeat FtsK_SpoIIIE PF01580.13 EJS42529.1 - 0.057 12.8 0.1 4.2 6.7 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.13 EJS42529.1 - 0.062 12.8 0.0 2.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.13 EJS42529.1 - 0.081 12.2 0.4 1 8.6 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_19 PF13245.1 EJS42529.1 - 0.098 12.4 0.1 6.9 6.5 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain ATP_bind_1 PF03029.12 EJS42529.1 - 0.22 11.0 1.5 8.3 5.8 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein EF-hand_7 PF13499.1 EJS42530.1 - 7.7e-05 22.7 0.6 7.7e-05 22.7 0.4 2.3 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EJS42530.1 - 0.00012 21.6 0.9 0.22 11.4 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EJS42530.1 - 0.00018 20.5 0.4 0.099 12.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EJS42530.1 - 0.0016 17.9 1.5 1.6 8.4 0.0 3.0 3 1 0 3 3 3 2 EF-hand domain pair Mpv17_PMP22 PF04117.7 EJS42531.1 - 8.9e-29 98.9 3.8 1.6e-28 98.1 2.7 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ABC1 PF03109.11 EJS42532.1 - 9e-34 115.9 0.1 2.3e-33 114.6 0.0 1.8 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.17 EJS42532.1 - 0.00086 18.6 0.0 0.005 16.2 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Tfb4 PF03850.9 EJS42532.1 - 0.011 15.0 0.1 0.029 13.6 0.0 1.7 2 0 0 2 2 2 0 Transcription factor Tfb4 bZIP_2 PF07716.10 EJS42533.1 - 5.8e-05 22.8 4.5 5.8e-05 22.8 3.1 3.6 3 1 0 3 3 3 1 Basic region leucine zipper ATG16 PF08614.6 EJS42533.1 - 0.0014 18.4 11.5 0.0014 18.4 8.0 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 EJS42533.1 - 0.0016 18.3 2.7 0.0016 18.3 1.9 3.1 3 1 1 4 4 3 1 bZIP transcription factor TPR_MLP1_2 PF07926.7 EJS42533.1 - 0.0033 17.1 9.7 0.0033 17.1 6.7 2.4 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein FUSC PF04632.7 EJS42533.1 - 0.028 12.8 0.3 0.03 12.7 0.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF724 PF05266.9 EJS42533.1 - 0.03 13.9 12.6 0.051 13.1 8.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF972 PF06156.8 EJS42533.1 - 0.057 13.7 13.0 0.046 14.0 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 EJS42533.1 - 0.099 11.6 17.2 0.047 12.7 10.3 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 Lebercilin PF15619.1 EJS42533.1 - 0.13 11.6 17.4 0.35 10.2 11.9 1.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.7 EJS42533.1 - 0.14 11.9 3.0 0.29 10.9 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 EJS42533.1 - 0.15 11.9 7.8 1.3 8.9 0.6 3.1 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EJS42533.1 - 0.22 11.3 20.8 0.074 12.9 4.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.8 EJS42533.1 - 0.27 11.1 15.3 0.26 11.2 9.7 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.16 EJS42533.1 - 0.29 10.5 15.1 1.7 8.0 0.9 2.2 1 1 0 2 2 2 0 Intermediate filament protein UPF0242 PF06785.6 EJS42533.1 - 0.3 9.7 7.5 0.33 9.5 5.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Baculo_PEP_C PF04513.7 EJS42533.1 - 0.3 10.8 7.1 0.5 10.1 4.3 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF904 PF06005.7 EJS42533.1 - 0.46 10.8 22.0 0.91 9.8 1.2 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF904) CENP-Q PF13094.1 EJS42533.1 - 0.47 10.4 18.9 1.7 8.6 13.1 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 EJS42533.1 - 0.55 10.1 21.1 0.55 10.1 5.9 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Tropomyosin PF00261.15 EJS42533.1 - 0.66 9.0 17.3 0.29 10.2 6.4 2.2 1 1 1 2 2 2 0 Tropomyosin Mnd1 PF03962.10 EJS42533.1 - 0.7 9.5 13.6 0.44 10.1 5.4 2.0 1 1 1 2 2 2 0 Mnd1 family DUF3450 PF11932.3 EJS42533.1 - 0.88 8.7 8.9 0.33 10.1 4.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.10 EJS42533.1 - 2.2 7.8 12.6 0.32 10.5 3.3 2.9 1 1 2 3 3 3 0 Septum formation initiator IncA PF04156.9 EJS42533.1 - 2.3 7.7 18.9 18 4.8 13.1 2.1 1 1 0 1 1 1 0 IncA protein DUF4404 PF14357.1 EJS42533.1 - 2.5 8.5 9.2 0.44 10.9 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) TSC22 PF01166.13 EJS42533.1 - 2.9 7.9 10.9 0.22 11.5 1.2 2.9 2 1 1 3 3 2 0 TSC-22/dip/bun family Phage_GP20 PF06810.6 EJS42533.1 - 3.6 6.9 16.5 1.2 8.5 0.4 2.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF4200 PF13863.1 EJS42533.1 - 3.7 7.4 15.9 0.93 9.4 6.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Bap31 PF05529.7 EJS42533.1 - 3.8 6.9 13.5 2.6 7.4 3.9 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like SlyX PF04102.7 EJS42533.1 - 3.9 7.9 10.0 8.2 6.8 4.3 3.2 1 1 2 3 3 3 0 SlyX bZIP_Maf PF03131.12 EJS42533.1 - 4.4 7.6 10.6 1 9.7 3.7 2.2 1 1 0 2 2 2 0 bZIP Maf transcription factor Prefoldin PF02996.12 EJS42533.1 - 4.4 6.9 12.3 2.8 7.5 1.0 3.2 2 1 1 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 EJS42533.1 - 4.7 7.0 20.8 0.28 11.0 4.1 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 EJS42533.1 - 5.2 7.2 12.0 7.2 6.8 0.6 3.3 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EJS42533.1 - 5.7 7.0 12.0 0.87 9.7 3.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DivIVA PF05103.8 EJS42533.1 - 6 6.9 15.8 8.1 6.5 4.8 2.4 1 1 1 2 2 2 0 DivIVA protein DUF2203 PF09969.4 EJS42533.1 - 6.5 6.9 6.5 2.4 8.3 1.6 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2730 PF10805.3 EJS42533.1 - 9 6.0 8.4 17 5.1 2.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Spc24 PF08286.6 EJS42533.1 - 9.8 5.9 17.9 39 3.9 1.6 3.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Glycogen_syn PF05693.8 EJS42534.1 - 0 1079.4 0.0 0 1079.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EJS42534.1 - 4.7e-11 42.3 0.0 1.6e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EJS42534.1 - 9e-06 25.9 0.0 1.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EJS42534.1 - 0.00014 21.4 0.1 0.00031 20.3 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain DUF3788 PF12663.2 EJS42534.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) Cpn60_TCP1 PF00118.19 EJS42535.1 - 1.3e-115 386.7 6.1 1.5e-115 386.5 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DAGK_cat PF00781.19 EJS42536.1 - 1.2e-25 89.4 0.0 2.2e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ras PF00071.17 EJS42537.1 - 1.2e-57 193.8 0.4 1.4e-57 193.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS42537.1 - 8.3e-23 81.1 0.2 2.6e-22 79.5 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EJS42537.1 - 3.6e-16 58.8 0.4 4e-16 58.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EJS42537.1 - 5.1e-06 25.8 0.1 6.4e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EJS42537.1 - 8.2e-06 25.7 0.0 1.5e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EJS42537.1 - 1.7e-05 24.3 0.0 9.3e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EJS42537.1 - 2.1e-05 23.8 0.0 3.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EJS42537.1 - 0.00033 20.4 1.4 0.00048 19.8 0.1 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EJS42537.1 - 0.002 18.2 0.0 0.015 15.4 0.0 2.1 1 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EJS42537.1 - 0.0037 16.7 0.5 0.029 13.8 0.4 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EJS42537.1 - 0.012 15.6 0.0 0.11 12.5 0.0 2.1 1 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EJS42537.1 - 0.018 14.2 0.0 0.044 12.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EJS42537.1 - 0.018 14.6 0.1 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EJS42537.1 - 0.021 14.3 0.1 0.66 9.4 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EJS42537.1 - 0.086 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TMA7 PF09072.5 EJS42538.1 - 2.6e-26 91.8 19.0 2.9e-26 91.7 13.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 rRNA_processing PF08524.6 EJS42538.1 - 0.086 12.6 4.2 0.1 12.3 2.9 1.1 1 0 0 1 1 1 0 rRNA processing FACT-Spt16_Nlob PF14826.1 EJS42538.1 - 0.35 10.3 2.0 0.37 10.3 1.4 1.0 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain Ribosomal_S28e PF01200.13 EJS42539.1 - 7.2e-34 115.3 3.6 7.8e-34 115.2 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e XLF PF09302.6 EJS42540.1 - 2.3e-26 92.6 4.0 3.3e-26 92.0 2.7 1.2 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Zein PF01559.11 EJS42541.1 - 0.016 14.5 0.1 0.11 11.7 0.0 2.2 2 1 0 2 2 2 0 Zein seed storage protein Longin PF13774.1 EJS42542.1 - 8.8e-21 73.2 1.3 1.7e-20 72.3 0.8 1.6 1 1 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EJS42542.1 - 6.9e-17 60.8 0.2 1.4e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 EJS42542.1 - 0.00046 19.9 0.4 0.00075 19.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Phi-29_GP16_7 PF06720.6 EJS42542.1 - 0.018 14.7 0.6 0.029 14.0 0.4 1.2 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 Mst1_SARAH PF11629.3 EJS42542.1 - 0.35 10.7 2.0 0.65 9.8 0.4 2.1 1 1 1 2 2 2 0 C terminal SARAH domain of Mst1 DcpS PF05652.7 EJS42543.1 - 5e-41 139.5 0.0 7.6e-41 138.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 EJS42543.1 - 1e-32 112.8 0.1 2.6e-32 111.4 0.1 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EJS42543.1 - 0.081 13.4 0.3 2.8 8.5 0.1 2.8 3 0 0 3 3 3 0 HIT domain Cnd1 PF12717.2 EJS42544.1 - 5.3e-54 182.7 12.9 3.5e-49 167.0 0.1 5.2 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EJS42544.1 - 8.9e-52 175.1 1.9 8.9e-52 175.1 1.3 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EJS42544.1 - 3.7e-13 49.5 0.0 2.5e-05 24.4 0.0 4.6 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EJS42544.1 - 4.6e-12 44.9 4.1 0.048 13.7 0.0 6.7 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.1 EJS42544.1 - 6.9e-07 29.5 0.3 1.2 9.6 0.0 5.1 4 0 0 4 4 4 2 HEAT-like repeat DUF2435 PF10363.4 EJS42544.1 - 0.002 18.0 0.6 1.5 8.7 0.0 4.7 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) MCM PF00493.18 EJS42545.1 - 6.3e-143 475.5 0.3 8.6e-143 475.0 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EJS42545.1 - 2.2e-20 73.3 1.3 4.3e-20 72.4 0.4 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EJS42545.1 - 3.9e-06 26.1 0.0 0.0007 18.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EJS42545.1 - 4.3e-06 26.4 0.0 1.4e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EJS42545.1 - 0.00056 19.5 0.1 0.0041 16.7 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EJS42545.1 - 0.023 14.1 0.0 1.4 8.3 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain PPV_E1_N PF00524.13 EJS42545.1 - 0.057 13.6 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 E1 Protein, N terminal domain DEAD PF00270.24 EJS42546.1 - 2.3e-42 144.3 0.5 4.7e-42 143.3 0.4 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS42546.1 - 2.7e-21 75.2 0.0 3e-10 39.8 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EJS42546.1 - 1.7e-06 28.0 0.7 6.5e-05 22.8 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DnaI_N PF07319.6 EJS42546.1 - 0.017 15.3 4.4 0.3 11.3 0.2 3.1 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus SecA_DEAD PF07517.9 EJS42546.1 - 0.038 13.2 0.2 4.3 6.5 0.0 2.7 2 0 0 2 2 2 0 SecA DEAD-like domain Kinesin-relat_1 PF12711.2 EJS42546.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.6 2 0 0 2 2 2 0 Kinesin motor CPSF73-100_C PF11718.3 EJS42547.1 - 5.3e-61 205.7 3.2 9.2e-61 204.9 2.2 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EJS42547.1 - 3.1e-31 107.9 0.0 1.9e-30 105.3 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EJS42547.1 - 2.5e-17 63.1 0.2 4.6e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EJS42547.1 - 1.5e-12 47.5 0.2 1.7e-11 44.0 0.1 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EJS42547.1 - 3.9e-11 42.5 0.0 8.4e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EJS42547.1 - 9.1e-07 28.7 0.2 1e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Zn_clus PF00172.13 EJS42548.1 - 1.4e-06 28.0 10.6 3.4e-06 26.8 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RF-1 PF00472.15 EJS42549.1 - 1.1e-19 70.3 2.8 1.7e-19 69.7 2.0 1.4 1 1 0 1 1 1 1 RF-1 domain OAD_gamma PF04277.8 EJS42550.1 - 0.18 12.2 0.8 4 7.8 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Methyltransf_16 PF10294.4 EJS42551.1 - 3.5e-14 52.6 0.0 5e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EJS42551.1 - 0.00042 20.0 0.0 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS42551.1 - 0.01 16.3 0.0 0.026 15.0 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EJS42551.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EJS42551.1 - 0.1 13.1 0.1 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Antimicrobial_1 PF08018.6 EJS42551.1 - 0.57 10.1 2.1 1.1 9.2 1.5 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide Hus1 PF04005.7 EJS42552.1 - 2e-21 76.2 0.2 1.7e-15 56.7 0.0 2.3 2 0 0 2 2 2 2 Hus1-like protein GTP_EFTU PF00009.22 EJS42553.1 - 9.8e-51 171.8 0.1 7e-50 169.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EJS42553.1 - 9.5e-40 134.8 8.7 1.3e-39 134.3 4.9 2.1 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EJS42553.1 - 4.2e-18 65.0 0.0 9.7e-18 63.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EJS42553.1 - 4.4e-07 29.9 1.6 1e-06 28.7 1.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EJS42553.1 - 5.8e-05 23.0 0.0 0.00017 21.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase NAD_binding_10 PF13460.1 EJS42554.1 - 2.4e-10 40.7 0.0 4.4e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EJS42554.1 - 2.5e-07 30.7 0.0 4.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EJS42554.1 - 4.5e-07 29.5 0.0 1.4e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EJS42554.1 - 2.2e-06 26.5 0.0 3.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EJS42554.1 - 8.9e-05 21.5 0.0 0.051 12.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein KR PF08659.5 EJS42554.1 - 0.029 14.0 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 EJS42554.1 - 0.04 13.1 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EJS42554.1 - 0.076 11.8 0.0 0.34 9.7 0.0 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain IF-2B PF01008.12 EJS42555.1 - 2.9e-93 311.9 0.1 3.7e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1804 PF08822.6 EJS42555.1 - 0.00025 20.8 0.0 0.00058 19.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) Ferritin PF00210.19 EJS42555.1 - 0.057 13.1 0.2 0.28 10.9 0.1 2.0 1 1 0 1 1 1 0 Ferritin-like domain TPR_2 PF07719.12 EJS42556.1 - 4.9e-08 32.2 0.3 1.9e-05 24.1 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EJS42556.1 - 1.6e-07 30.5 0.2 5.6e-05 22.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EJS42556.1 - 1.8e-07 30.7 1.0 0.00027 20.5 0.0 2.5 2 1 0 2 2 2 2 TPR repeat TPR_19 PF14559.1 EJS42556.1 - 2.3e-05 24.6 2.1 2.5e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EJS42556.1 - 2.5e-05 24.8 1.0 0.024 15.2 0.0 2.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EJS42556.1 - 8.2e-05 22.9 0.7 0.00025 21.3 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EJS42556.1 - 0.0017 18.2 0.6 0.014 15.3 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EJS42556.1 - 0.0034 16.4 0.1 0.0071 15.4 0.0 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EJS42556.1 - 0.0044 16.7 0.0 0.027 14.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EJS42556.1 - 0.0053 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EJS42556.1 - 0.014 15.5 0.6 0.08 13.0 0.4 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EJS42556.1 - 0.043 14.0 0.0 0.79 10.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EJS42556.1 - 0.044 13.6 2.4 0.25 11.2 0.5 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EJS42556.1 - 0.055 13.3 0.5 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Ras PF00071.17 EJS42557.1 - 1.4e-51 174.0 0.0 1.7e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS42557.1 - 5.2e-18 65.6 0.0 1.1e-17 64.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EJS42557.1 - 4.1e-12 45.6 0.0 5.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EJS42557.1 - 0.00023 21.3 0.2 0.0019 18.3 0.2 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EJS42557.1 - 0.00056 19.1 0.0 0.00081 18.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EJS42557.1 - 0.0046 16.4 0.6 0.043 13.2 0.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EJS42557.1 - 0.0088 15.2 0.0 0.015 14.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit KaiC PF06745.8 EJS42557.1 - 0.014 14.4 0.2 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 KaiC Pox_A32 PF04665.7 EJS42557.1 - 0.027 13.7 0.1 0.048 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EJS42557.1 - 0.043 12.4 3.0 1.3 7.5 0.1 2.9 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 EJS42557.1 - 0.052 13.6 0.2 0.17 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EJS42557.1 - 0.064 13.1 0.3 0.15 11.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EJS42557.1 - 0.12 12.0 0.2 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 NACHT domain ATP_sub_h PF10775.4 EJS42558.1 - 4.1e-25 87.2 0.3 5.4e-25 86.9 0.2 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h zf-U1 PF06220.7 EJS42559.1 - 1e-18 66.5 5.6 1e-18 66.5 3.9 1.8 2 0 0 2 2 2 1 U1 zinc finger Sec62 PF03839.11 EJS42559.1 - 0.45 9.8 3.6 0.69 9.2 2.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 G_glu_transpept PF01019.16 EJS42560.1 - 3e-142 474.6 0.0 3.6e-142 474.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cellulase PF00150.13 EJS42561.1 - 1e-13 51.1 0.4 2.2e-13 50.0 0.2 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cys_Met_Meta_PP PF01053.15 EJS42563.1 - 5.7e-151 502.1 0.0 6.5e-151 502.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EJS42563.1 - 9.9e-11 41.2 0.0 1.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EJS42563.1 - 1.5e-09 37.3 0.0 2.1e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EJS42563.1 - 4.7e-09 35.8 0.0 1.1e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EJS42563.1 - 1.2e-07 30.8 0.1 2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EJS42563.1 - 0.00015 20.2 0.1 0.00023 19.5 0.1 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EJS42563.1 - 0.021 13.5 0.0 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Phg_2220_C PF09524.5 EJS42563.1 - 0.043 13.8 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) Aconitase PF00330.15 EJS42564.1 - 5.5e-183 608.6 0.0 1.2e-182 607.5 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EJS42564.1 - 5.7e-49 165.5 0.0 1.1e-48 164.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PI3_PI4_kinase PF00454.22 EJS42565.1 - 1.7e-44 152.0 0.0 1.1e-43 149.4 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EJS42565.1 - 7.7e-38 129.5 0.1 1.6e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) SP2 PF03014.9 EJS42566.1 - 0.059 11.2 0.0 0.065 11.1 0.0 1.1 1 0 0 1 1 1 0 Structural protein 2 GRIP PF01465.15 EJS42567.1 - 9.1e-15 53.9 0.6 2.5e-14 52.4 0.4 1.9 1 0 0 1 1 1 1 GRIP domain MscS_porin PF12795.2 EJS42567.1 - 0.00027 20.3 24.8 0.00027 20.3 17.2 6.6 3 2 4 7 7 7 2 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 EJS42567.1 - 0.0013 17.2 37.3 0.0013 17.2 25.9 5.3 1 1 3 5 5 5 1 AAA domain Laminin_II PF06009.7 EJS42567.1 - 0.0043 16.7 9.7 0.0043 16.7 6.7 9.6 4 3 6 10 10 10 4 Laminin Domain II FlxA PF14282.1 EJS42567.1 - 0.0091 15.9 7.3 0.0091 15.9 5.0 11.0 4 3 6 11 11 11 2 FlxA-like protein ATG16 PF08614.6 EJS42567.1 - 0.27 11.0 154.0 0.21 11.4 17.8 9.0 2 1 5 8 8 8 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EJS42567.1 - 0.83 8.7 67.7 0.043 12.9 3.7 6.6 2 2 5 7 7 7 0 Reovirus sigma C capsid protein BicD PF09730.4 EJS42567.1 - 1.7 6.8 135.7 0.054 11.8 17.0 5.1 1 1 4 5 5 5 0 Microtubule-associated protein Bicaudal-D DUF1409 PF07197.7 EJS42567.1 - 1.9 8.6 20.9 1.7 8.7 0.3 6.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1409) Septin PF00735.13 EJS42569.1 - 5.5e-121 402.8 4.3 5.5e-121 402.8 3.0 2.1 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.22 EJS42569.1 - 0.00016 21.1 4.1 0.0011 18.4 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EJS42569.1 - 0.00073 19.6 0.0 0.0041 17.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EJS42569.1 - 0.0011 19.2 0.0 0.0011 19.2 0.0 2.7 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.1 EJS42569.1 - 0.004 17.1 0.0 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EJS42569.1 - 0.0045 16.8 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EJS42569.1 - 0.0063 16.4 0.7 0.039 13.9 0.0 2.5 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 EJS42569.1 - 0.027 14.6 0.2 0.55 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EJS42569.1 - 0.072 13.2 0.1 0.52 10.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EJS42569.1 - 0.69 9.8 17.8 0.56 10.1 4.6 2.5 2 1 0 2 2 2 0 AAA domain SNF5 PF04855.7 EJS42570.1 - 5.1e-64 216.0 4.0 1.4e-61 208.1 2.8 2.4 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DUF4296 PF14129.1 EJS42570.1 - 0.18 11.9 3.0 0.34 11.0 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) zf-CCCH PF00642.19 EJS42571.1 - 6.6e-10 38.4 3.0 1.4e-09 37.4 2.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EJS42571.1 - 3.6e-09 36.4 9.4 7.1e-09 35.5 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EJS42571.1 - 1.1e-07 31.4 11.0 2e-07 30.5 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EJS42571.1 - 1.3e-07 31.1 7.6 2.2e-07 30.4 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EJS42571.1 - 3e-06 26.9 7.9 6e-06 25.9 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EJS42571.1 - 2.1e-05 24.0 7.7 3.9e-05 23.2 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EJS42571.1 - 0.0045 16.8 8.6 0.01 15.6 6.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EJS42571.1 - 0.0052 16.4 6.9 0.016 14.9 4.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EJS42571.1 - 0.0096 15.6 2.0 0.016 15.0 1.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EJS42571.1 - 0.023 14.2 5.4 0.05 13.1 3.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 EJS42571.1 - 0.16 12.1 3.9 0.37 10.9 2.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-P11 PF03854.9 EJS42571.1 - 0.79 9.2 5.0 1.7 8.1 3.5 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.1 EJS42571.1 - 1.6 8.3 7.3 4.5 6.9 2.5 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Pex24p PF06398.6 EJS42572.1 - 4e-88 295.6 10.2 6.5e-88 294.9 7.1 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribosomal_L38e PF01781.13 EJS42573.1 - 2.2e-27 94.5 2.4 2.5e-27 94.4 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family PapD_C PF02753.12 EJS42573.1 - 0.083 12.7 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain HABP4_PAI-RBP1 PF04774.10 EJS42574.1 - 1.2e-05 25.7 1.5 1.6e-05 25.3 0.9 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family CTP_transf_2 PF01467.21 EJS42575.1 - 3.6e-37 127.8 0.0 5.3e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Mid2 PF04478.7 EJS42576.1 - 1.8e-73 245.0 2.7 1.8e-73 245.0 1.9 3.5 1 1 3 4 4 4 1 Mid2 like cell wall stress sensor DUF605 PF04652.11 EJS42576.1 - 0.00072 19.0 19.1 0.00072 19.0 13.2 1.6 2 0 0 2 2 2 1 Vta1 like SKG6 PF08693.5 EJS42576.1 - 0.0052 16.0 3.2 0.0052 16.0 2.2 2.9 2 1 0 2 2 2 1 Transmembrane alpha-helix domain DUF912 PF06024.7 EJS42576.1 - 0.17 11.9 0.1 0.17 11.9 0.0 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_S25 PF03297.10 EJS42577.1 - 7.5e-45 151.2 4.6 8.4e-45 151.1 3.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 EJS42577.1 - 0.00011 21.8 0.1 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain EAP30 PF04157.11 EJS42577.1 - 0.025 13.7 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_CodY PF08222.6 EJS42577.1 - 0.043 13.1 0.1 0.067 12.5 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain TAF4 PF05236.9 EJS42577.1 - 0.065 12.5 0.1 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Gp49 PF05973.9 EJS42577.1 - 0.11 12.4 1.1 3.6 7.6 0.4 2.2 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) MerR PF00376.18 EJS42577.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein Ribosomal_L10 PF00466.15 EJS42578.1 - 1.2e-26 92.5 0.2 2e-26 91.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EJS42578.1 - 4e-19 68.7 5.1 4.5e-19 68.6 2.0 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Glucan_synthase PF02364.10 EJS42579.1 - 0 1467.6 0.0 0 1467.2 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EJS42579.1 - 2.7e-39 133.7 0.1 6.4e-39 132.4 0.1 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 EJS42580.1 - 3.9e-138 459.6 0.8 5.2e-138 459.3 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EJS42580.1 - 1.6e-16 60.5 0.8 4.5e-16 59.0 0.5 1.8 1 0 0 1 1 1 1 X8 domain HEAT_EZ PF13513.1 EJS42582.1 - 7.2e-15 54.9 11.4 2.4e-07 31.0 0.0 9.6 8 1 3 11 11 11 3 HEAT-like repeat HEAT PF02985.17 EJS42582.1 - 4.4e-14 51.2 17.6 0.00013 21.7 0.0 10.6 12 0 0 12 12 12 4 HEAT repeat IBN_N PF03810.14 EJS42582.1 - 4.4e-12 45.7 6.7 8.5e-11 41.6 1.4 4.4 4 1 1 5 5 5 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EJS42582.1 - 4.6e-12 46.0 7.8 0.00018 21.7 0.0 6.9 3 1 4 7 7 7 4 HEAT repeats CLASP_N PF12348.3 EJS42582.1 - 0.00081 18.8 2.3 0.42 9.9 0.0 4.4 4 1 1 5 5 5 1 CLASP N terminal Arm PF00514.18 EJS42582.1 - 0.027 14.2 9.3 0.046 13.5 0.0 5.3 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 EJS42582.1 - 0.037 14.3 1.3 12 6.3 0.0 4.4 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Mito_carr PF00153.22 EJS42583.1 - 1.8e-56 187.8 0.8 8.4e-20 70.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CN_hydrolase PF00795.17 EJS42584.1 - 6e-35 120.2 0.0 1.3e-34 119.1 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase LRR_4 PF12799.2 EJS42585.1 - 1e-05 24.9 14.7 0.0057 16.2 0.1 5.7 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EJS42585.1 - 0.0005 19.7 1.3 2.4 7.9 0.0 3.4 3 0 0 3 3 3 2 F-box-like LRR_8 PF13855.1 EJS42585.1 - 0.0026 17.5 10.6 0.015 15.0 0.7 4.6 4 2 1 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 EJS42585.1 - 0.0035 17.2 2.9 73 4.2 0.0 6.2 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 EJS42585.1 - 0.013 15.3 9.1 12 6.3 0.2 6.8 6 1 1 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.1 EJS42585.1 - 3.4 8.0 12.3 7.9 6.8 0.1 6.2 6 0 0 6 6 6 0 Leucine Rich repeat Transaldolase PF00923.14 EJS42587.1 - 2.8e-99 331.8 0.0 3.3e-99 331.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase DUF740 PF05340.7 EJS42587.1 - 0.082 11.2 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) YajC PF02699.10 EJS42587.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Lipoxygenase PF00305.14 EJS42587.1 - 0.11 10.4 0.0 0.17 9.8 0.0 1.2 1 0 0 1 1 1 0 Lipoxygenase IlvC PF01450.14 EJS42588.1 - 3.6e-48 163.1 0.0 5.4e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 EJS42588.1 - 8.4e-46 155.3 0.0 1.2e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EJS42588.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Bromodomain PF00439.20 EJS42590.1 - 2.9e-28 97.6 3.2 4.6e-13 48.8 0.1 2.9 3 0 0 3 3 3 2 Bromodomain BAH PF01426.13 EJS42590.1 - 1.7e-22 79.3 0.1 7.5e-22 77.3 0.0 2.2 2 0 0 2 2 2 1 BAH domain Lyase_1 PF00206.15 EJS42591.1 - 3.6e-24 85.5 0.0 8.5e-24 84.2 0.0 1.6 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.4 EJS42591.1 - 3e-16 59.2 0.0 1.5e-15 56.9 0.0 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.6 EJS42591.1 - 0.059 12.8 0.1 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Pox_A_type_inc PF04508.7 EJS42593.1 - 2.7 8.0 5.6 10 6.1 0.1 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PIN_4 PF13638.1 EJS42594.1 - 0.0072 16.4 0.0 0.018 15.1 0.0 1.7 1 1 0 1 1 1 1 PIN domain DUF2462 PF09495.5 EJS42595.1 - 1.7e-19 70.3 12.5 2.4e-19 69.8 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Glutaredoxin PF00462.19 EJS42596.1 - 3.7e-05 23.6 0.0 5.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 EJS42596.1 - 0.0076 15.8 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.6 EJS42596.1 - 0.016 14.6 0.6 0.021 14.2 0.4 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) F-box-like PF12937.2 EJS42597.1 - 8.3e-05 22.2 0.9 0.00026 20.6 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EJS42597.1 - 0.001 18.6 0.9 0.0022 17.6 0.6 1.6 1 0 0 1 1 1 1 F-box domain Roughex PF06020.6 EJS42597.1 - 0.18 10.4 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein P21-Arc PF04062.9 EJS42598.1 - 2.6e-81 271.5 0.2 2.9e-81 271.4 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CNH PF00780.17 EJS42599.1 - 3.5e-80 269.3 1.3 3.9e-80 269.1 0.2 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EJS42599.1 - 2.3e-38 131.1 0.0 2.3e-38 131.1 0.0 3.3 2 1 1 3 3 3 1 Pleckstrin homology domain RhoGEF PF00621.15 EJS42599.1 - 2.4e-32 112.2 2.1 5.7e-32 111.0 0.0 2.6 3 0 0 3 3 3 1 RhoGEF domain DEP PF00610.16 EJS42599.1 - 1.5e-13 50.2 0.0 3.8e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ELO PF01151.13 EJS42600.1 - 1.5e-62 211.1 27.4 2e-62 210.7 19.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2457 PF10446.4 EJS42601.1 - 9.2 4.8 12.7 15 4.2 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-C2H2_6 PF13912.1 EJS42602.1 - 0.00034 20.4 10.4 0.0049 16.7 0.4 4.2 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EJS42602.1 - 0.0014 18.8 4.0 0.0014 18.8 2.8 4.9 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EJS42602.1 - 0.003 17.7 3.6 0.003 17.7 2.5 5.3 5 1 1 6 6 6 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EJS42602.1 - 0.0044 17.2 3.2 0.0044 17.2 2.2 4.8 5 0 0 5 5 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EJS42602.1 - 0.017 15.2 4.0 0.2 11.8 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C3HC4_3 PF13920.1 EJS42602.1 - 0.03 13.9 4.3 2.4 7.8 0.1 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Sirohm_synth_C PF14823.1 EJS42602.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal zf-RING_2 PF13639.1 EJS42602.1 - 0.082 12.7 5.1 17 5.3 0.4 3.4 3 0 0 3 3 3 0 Ring finger domain zf-RING_3 PF14369.1 EJS42602.1 - 0.18 11.8 4.4 0.49 10.4 0.2 3.2 3 0 0 3 3 3 0 zinc-finger zf-Di19 PF05605.7 EJS42602.1 - 0.29 11.3 9.6 0.75 9.9 2.9 3.7 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.9 EJS42602.1 - 0.86 9.1 5.1 0.48 9.9 0.1 2.6 1 1 1 2 2 2 0 Rad50 zinc hook motif zf-RING_5 PF14634.1 EJS42602.1 - 0.9 9.3 8.3 7.7 6.3 0.3 3.4 3 0 0 3 3 3 0 zinc-RING finger domain Zn-ribbon_8 PF09723.5 EJS42602.1 - 1.1 9.2 6.0 59 3.7 0.1 3.7 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2HC_2 PF13913.1 EJS42602.1 - 1.5 8.5 12.2 1.7 8.4 0.8 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Maelstrom PF13017.1 EJS42603.1 - 0.054 12.9 0.8 0.24 10.8 0.1 1.9 2 0 0 2 2 2 0 piRNA pathway germ-plasm component DUF835 PF05763.7 EJS42603.1 - 0.3 10.6 2.1 17 4.9 0.3 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF835) FBPase PF00316.15 EJS42604.1 - 2.7e-143 476.6 0.0 3.1e-143 476.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase SecY PF00344.15 EJS42605.1 - 1.4e-86 290.5 18.7 1.8e-86 290.2 13.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EJS42605.1 - 1e-18 66.4 0.9 6.8e-18 63.8 0.1 3.0 2 0 0 2 2 2 1 Plug domain of Sec61p CRAL_TRIO PF00650.15 EJS42606.1 - 2.6e-43 147.2 0.1 4.5e-43 146.4 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EJS42606.1 - 3.3e-10 39.9 0.1 1.1e-09 38.3 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EJS42606.1 - 5.7e-07 29.5 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF615 PF04751.9 EJS42606.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF615) tRNA-synt_1 PF00133.17 EJS42608.1 - 1e-58 198.8 0.6 4.8e-34 117.3 3.2 6.5 1 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EJS42608.1 - 2.2e-40 137.9 0.0 3.5e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EJS42608.1 - 1.4e-33 116.1 0.1 1.4e-25 89.7 0.1 4.4 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1d PF00750.14 EJS42608.1 - 2.6e-05 23.2 0.0 5.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EJS42608.1 - 0.00028 20.1 0.0 0.097 11.7 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DNA_ligase_ZBD PF03119.11 EJS42608.1 - 0.019 14.6 0.0 0.049 13.3 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain AAA_23 PF13476.1 EJS42609.1 - 1.6e-18 67.8 7.4 1.6e-18 67.8 5.1 5.9 3 2 2 5 5 3 1 AAA domain SMC_N PF02463.14 EJS42609.1 - 2.6e-16 59.5 42.4 1e-15 57.5 29.4 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EJS42609.1 - 0.00034 20.0 0.1 0.0011 18.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EJS42609.1 - 0.00063 18.8 28.1 0.00063 18.8 19.5 3.2 2 1 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.1 EJS42609.1 - 0.00087 19.3 29.9 0.0037 17.2 0.2 4.3 3 2 0 3 3 3 2 AAA domain Filament PF00038.16 EJS42609.1 - 0.0026 17.2 32.8 0.0026 17.2 22.7 3.6 2 1 0 2 2 2 2 Intermediate filament protein DUF4094 PF13334.1 EJS42609.1 - 0.016 15.5 2.9 0.016 15.5 2.0 5.3 6 1 2 8 8 7 0 Domain of unknown function (DUF4094) SbcCD_C PF13558.1 EJS42609.1 - 0.029 14.2 0.0 0.1 12.5 0.0 2.0 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 EJS42609.1 - 0.042 13.0 24.3 0.89 8.6 0.3 4.6 2 2 2 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EJS42609.1 - 0.11 10.8 87.7 0.15 10.4 16.7 5.7 3 2 2 5 5 5 0 AAA domain DUF1664 PF07889.7 EJS42609.1 - 8.8 6.1 52.4 1.4 8.7 1.3 6.5 3 2 2 6 6 6 0 Protein of unknown function (DUF1664) Vac14_Fig4_bd PF11916.3 EJS42610.1 - 3.4e-70 234.8 6.0 9e-70 233.5 4.2 1.8 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EJS42610.1 - 3.8e-47 158.6 0.3 1.1e-38 131.5 0.0 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EJS42610.1 - 1.8e-11 43.1 5.7 0.00024 20.9 0.0 7.3 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 EJS42610.1 - 1.8e-07 31.3 0.1 0.025 14.8 0.0 4.9 4 1 0 4 4 4 1 HEAT repeats CLASP_N PF12348.3 EJS42610.1 - 3.1e-07 29.9 3.3 0.052 12.8 1.3 4.4 4 1 0 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 EJS42610.1 - 1.2e-06 28.8 0.5 0.6 10.6 0.0 5.8 6 0 0 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 EJS42610.1 - 0.00033 20.5 13.3 0.22 11.3 0.9 5.1 6 0 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EJS42610.1 - 0.017 15.0 5.2 0.63 9.9 0.3 3.5 4 0 0 4 4 4 0 Parkin co-regulated protein Arm PF00514.18 EJS42610.1 - 0.025 14.3 4.4 1.5 8.7 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat zf-C2H2_2 PF12756.2 EJS42611.1 - 7e-31 106.3 7.0 5e-29 100.3 1.5 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Ribosomal_S14 PF00253.16 EJS42612.1 - 1.2e-17 63.0 4.8 1.3e-17 62.8 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EJS42612.1 - 0.031 14.0 0.3 0.035 13.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Prim_Zn_Ribbon PF08273.7 EJS42612.1 - 0.061 13.4 2.0 0.95 9.5 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase RNA_POL_M_15KD PF02150.11 EJS42612.1 - 0.43 10.3 2.5 6.2 6.6 0.2 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit CFEM PF05730.6 EJS42613.1 - 1.2e-08 34.6 14.0 3.5e-08 33.1 9.7 1.8 1 0 0 1 1 1 1 CFEM domain DUF605 PF04652.11 EJS42613.1 - 0.16 11.3 28.5 0.18 11.1 19.8 1.1 1 0 0 1 1 1 0 Vta1 like FAM196 PF15265.1 EJS42613.1 - 0.6 9.2 34.9 0.72 9.0 24.2 1.0 1 0 0 1 1 1 0 FAM196 family Hex_IIIa PF02455.11 EJS42613.1 - 6.8 5.2 16.2 8.7 4.9 11.2 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Peptidase_S64 PF08192.6 EJS42613.1 - 8.1 4.6 32.8 9.9 4.3 22.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 Arrestin_N PF00339.24 EJS42614.1 - 2e-05 24.4 0.1 0.0001 22.1 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ATP-synt_10 PF05176.9 EJS42615.1 - 1.9e-83 279.6 1.4 2.3e-83 279.3 1.0 1.0 1 0 0 1 1 1 1 ATP10 protein COX7C PF02935.11 EJS42616.1 - 3.9e-27 93.8 1.4 4.8e-27 93.5 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Sec1 PF00995.18 EJS42617.1 - 2.7e-87 293.7 8.8 3.2e-87 293.4 6.1 1.0 1 0 0 1 1 1 1 Sec1 family AAA PF00004.24 EJS42618.1 - 2e-90 299.8 0.0 6.5e-44 149.3 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EJS42618.1 - 2.4e-13 49.7 0.0 1.5e-05 24.1 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EJS42618.1 - 3.2e-12 46.8 0.1 5.3e-06 26.5 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 EJS42618.1 - 1.7e-11 44.0 0.1 3.9e-05 23.4 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EJS42618.1 - 1.2e-10 41.6 0.4 0.00023 21.3 0.0 4.3 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.9 EJS42618.1 - 7.4e-10 38.9 0.0 7.6e-05 22.6 0.0 2.9 2 2 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EJS42618.1 - 4.4e-09 36.3 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EJS42618.1 - 8.1e-07 29.0 0.0 0.00043 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EJS42618.1 - 1.1e-06 29.4 0.0 0.0087 16.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EJS42618.1 - 1.9e-06 26.8 0.0 0.0048 15.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 EJS42618.1 - 7.6e-06 26.0 0.0 0.13 12.4 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 EJS42618.1 - 1.8e-05 24.3 3.2 0.0036 17.0 0.1 3.6 4 0 0 4 4 3 1 Part of AAA domain AAA_28 PF13521.1 EJS42618.1 - 2.3e-05 24.4 0.0 0.061 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EJS42618.1 - 2.4e-05 23.8 6.7 0.084 12.2 0.0 4.1 2 2 1 3 3 3 2 AAA domain Sigma54_activ_2 PF14532.1 EJS42618.1 - 3.1e-05 24.0 0.0 0.096 12.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 EJS42618.1 - 5.3e-05 22.4 0.1 0.14 11.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EJS42618.1 - 0.00014 21.0 0.1 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.10 EJS42618.1 - 0.00041 19.1 0.0 0.032 12.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 EJS42618.1 - 0.00042 20.0 0.1 0.055 13.1 0.0 3.4 3 1 0 4 4 3 1 NACHT domain Arch_ATPase PF01637.13 EJS42618.1 - 0.00077 19.2 0.0 0.66 9.6 0.0 2.8 2 1 0 2 2 2 1 Archaeal ATPase IstB_IS21 PF01695.12 EJS42618.1 - 0.0016 17.9 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_3 PF07726.6 EJS42618.1 - 0.0018 17.8 0.0 2.2 7.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EJS42618.1 - 0.0039 17.1 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain ABC_tran PF00005.22 EJS42618.1 - 0.005 17.1 0.1 0.15 12.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 EJS42618.1 - 0.0067 15.9 0.2 7 6.0 0.0 4.1 3 2 0 3 3 3 0 Sigma-54 interaction domain Bac_DnaA PF00308.13 EJS42618.1 - 0.007 16.0 0.0 0.18 11.3 0.0 2.5 2 1 0 2 2 2 1 Bacterial dnaA protein KaiC PF06745.8 EJS42618.1 - 0.0086 15.2 0.4 11 5.0 0.0 3.5 2 1 1 3 3 3 0 KaiC AAA_11 PF13086.1 EJS42618.1 - 0.011 15.3 0.0 0.57 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EJS42618.1 - 0.012 15.1 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EJS42618.1 - 0.016 14.0 0.7 2.2 7.0 0.0 2.9 2 1 0 3 3 3 0 Type II/IV secretion system protein AAA_30 PF13604.1 EJS42618.1 - 0.02 14.4 0.2 0.097 12.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EJS42618.1 - 0.02 15.1 0.0 0.61 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EJS42618.1 - 0.035 13.0 0.0 1.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EJS42618.1 - 0.036 13.6 0.4 6 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EJS42618.1 - 0.088 12.4 0.1 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AFG1_ATPase PF03969.11 EJS42618.1 - 0.13 11.0 0.0 0.3 9.8 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase DSHCT PF08148.7 EJS42619.1 - 5.3e-59 198.4 0.2 1.1e-58 197.4 0.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EJS42619.1 - 1.2e-22 80.2 0.1 2.4e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS42619.1 - 1.2e-06 28.2 0.0 3.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EJS42619.1 - 2.8e-06 26.7 0.4 7.4e-06 25.3 0.2 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain Translin PF01997.11 EJS42619.1 - 0.0069 16.0 0.2 0.021 14.4 0.1 1.8 1 0 0 1 1 1 1 Translin family Bromodomain PF00439.20 EJS42620.1 - 4e-41 138.8 0.6 9.6e-20 70.3 0.1 2.6 2 0 0 2 2 2 2 Bromodomain zf-C2H2_4 PF13894.1 EJS42621.1 - 0.00028 20.9 16.2 0.054 13.8 0.3 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EJS42621.1 - 0.0035 17.4 4.5 0.15 12.2 0.0 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EJS42621.1 - 0.0073 16.5 16.8 0.031 14.5 0.4 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EJS42621.1 - 0.041 14.2 20.5 0.1 13.0 1.2 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type Nucleoplasmin PF03066.10 EJS42621.1 - 2.5 7.5 18.4 6.5 6.2 12.8 1.6 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EJS42621.1 - 4.7 6.7 10.5 11 5.5 7.2 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 EJS42621.1 - 6.8 7.0 17.6 2 8.7 9.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Utp21 PF04192.7 EJS42622.1 - 1.9e-83 279.2 1.1 2.7e-83 278.7 0.7 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EJS42622.1 - 6.7e-21 73.3 17.0 2.3e-08 33.6 0.3 8.5 9 0 0 9 9 9 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EJS42622.1 - 8e-06 25.4 0.0 0.023 14.1 0.0 3.6 2 1 1 3 3 3 2 PQQ-like domain eIF2A PF08662.6 EJS42622.1 - 8.4e-05 22.3 0.1 0.88 9.2 0.0 3.5 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A SGL PF08450.7 EJS42622.1 - 0.0033 16.8 0.5 12 5.2 0.0 4.5 4 1 0 4 4 4 1 SMP-30/Gluconolaconase/LRE-like region Apc4_WD40 PF12894.2 EJS42622.1 - 0.0046 16.4 0.0 17 4.9 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.11 EJS42622.1 - 0.011 14.1 0.0 0.069 11.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EJS42622.1 - 0.014 14.2 4.6 0.13 10.9 0.1 3.3 4 1 0 5 5 5 0 Nup133 N terminal like Ctr PF04145.10 EJS42623.1 - 1.3e-43 148.5 0.2 1.7e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF3010 PF11215.3 EJS42623.1 - 0.028 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) SRR1 PF07985.7 EJS42624.1 - 6.9e-14 51.5 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 SUR7 PF06687.7 EJS42625.1 - 3.4e-13 49.6 24.6 5e-12 45.8 17.1 2.8 1 1 0 1 1 1 1 SUR7/PalI family DUF1019 PF06254.6 EJS42625.1 - 0.025 14.7 0.4 5.8 7.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1019) HEAT_2 PF13646.1 EJS42625.1 - 0.67 10.2 7.2 22 5.4 0.2 3.8 2 2 1 3 3 3 0 HEAT repeats DUF4131 PF13567.1 EJS42625.1 - 5.5 6.3 6.1 56 3.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SUR7 PF06687.7 EJS42626.1 - 3.4e-41 141.1 15.6 4e-41 140.9 10.8 1.0 1 0 0 1 1 1 1 SUR7/PalI family Chordopox_A33R PF05966.7 EJS42626.1 - 0.0043 15.8 0.3 0.0071 15.1 0.2 1.3 1 0 0 1 1 1 1 Chordopoxvirus A33R protein Fig1 PF12351.3 EJS42626.1 - 0.014 15.2 8.3 0.04 13.8 5.8 1.8 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 V_ATPase_I PF01496.14 EJS42626.1 - 0.45 8.3 5.7 0.56 7.9 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3332 PF11810.3 EJS42626.1 - 0.46 10.1 3.4 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) MtrG PF04210.8 EJS42626.1 - 1.6 8.4 5.4 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G CDC73 PF05179.9 EJS42627.1 - 1.4e-85 287.0 0.0 2.4e-85 286.1 0.0 1.4 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family OB_NTP_bind PF07717.11 EJS42628.1 - 7.5e-24 83.7 0.0 2.5e-23 82.0 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EJS42628.1 - 5e-11 42.5 0.2 3.5e-10 39.8 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EJS42628.1 - 6.2e-11 42.0 0.1 1.7e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 EJS42628.1 - 9.5e-11 41.5 1.0 3.3e-10 39.8 0.7 2.0 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EJS42628.1 - 1.3e-10 41.0 1.3 4.3e-10 39.3 0.6 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 EJS42628.1 - 0.0003 20.1 1.5 0.00094 18.4 1.0 1.8 1 1 0 1 1 1 1 PhoH-like protein AAA_29 PF13555.1 EJS42628.1 - 0.00064 19.2 0.0 0.0016 17.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 EJS42628.1 - 0.00065 19.3 0.6 0.0021 17.7 0.1 2.2 2 0 0 2 2 2 1 NACHT domain T2SE PF00437.15 EJS42628.1 - 0.0007 18.5 0.0 0.0021 17.0 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein UBA PF00627.26 EJS42628.1 - 0.00089 19.0 0.2 0.0018 18.0 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain AAA_22 PF13401.1 EJS42628.1 - 0.0012 19.0 0.1 0.0063 16.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EJS42628.1 - 0.0012 18.8 0.1 0.01 15.8 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EJS42628.1 - 0.0014 18.0 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EJS42628.1 - 0.0014 18.1 1.6 0.58 9.5 0.1 3.2 3 0 0 3 3 3 1 AAA-like domain AAA_19 PF13245.1 EJS42628.1 - 0.0014 18.3 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EJS42628.1 - 0.0021 17.5 0.1 0.0055 16.2 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EJS42628.1 - 0.007 16.7 0.4 0.007 16.7 0.3 4.7 2 1 1 4 4 3 1 AAA domain Zot PF05707.7 EJS42628.1 - 0.012 15.1 0.1 0.047 13.1 0.0 2.0 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) KaiC PF06745.8 EJS42628.1 - 0.052 12.6 0.1 0.052 12.6 0.0 2.6 3 0 0 3 3 3 0 KaiC APG17 PF04108.7 EJS42629.1 - 3.9e-110 368.4 23.4 4.4e-110 368.2 16.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 SpoIIID PF12116.3 EJS42629.1 - 0.049 13.5 2.5 5.2 7.0 0.1 3.2 3 0 0 3 3 3 0 Stage III sporulation protein D PMC2NT PF08066.7 EJS42629.1 - 0.26 11.5 8.8 0.3 11.4 0.7 3.4 3 1 1 4 4 4 0 PMC2NT (NUC016) domain HxlR PF01638.12 EJS42629.1 - 3.3 7.3 5.6 6.9 6.3 0.1 3.0 3 0 0 3 3 3 0 HxlR-like helix-turn-helix DUF4473 PF14747.1 EJS42629.1 - 5.9 7.1 7.8 2.2 8.5 1.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF1900 PF08954.6 EJS42630.1 - 3.8e-49 165.7 0.0 4.6e-48 162.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EJS42630.1 - 1.3e-31 108.0 0.2 2.3e-31 107.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EJS42630.1 - 1.3e-23 81.9 5.6 1.3e-06 28.0 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EJS42630.1 - 1.3e-05 23.5 0.2 0.00082 17.6 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EJS42630.1 - 2e-05 24.4 0.1 0.01 15.5 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Hom_end_hint PF05203.11 EJS42631.1 - 0.02 14.6 3.4 0.042 13.5 2.2 1.8 1 1 0 1 1 1 0 Hom_end-associated Hint Tropomyosin_1 PF12718.2 EJS42631.1 - 1.2 8.9 16.5 0.079 12.8 4.6 2.8 1 1 1 2 2 2 0 Tropomyosin like Jnk-SapK_ap_N PF09744.4 EJS42631.1 - 3.8 7.4 17.7 5.4 6.9 3.1 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Ribosomal_L29 PF00831.18 EJS42631.1 - 7.8 6.2 10.7 7.9 6.2 0.3 4.4 4 1 1 5 5 5 0 Ribosomal L29 protein IMPDH PF00478.20 EJS42632.1 - 2.4e-142 474.0 1.9 2.8e-142 473.7 1.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EJS42632.1 - 1.3e-15 56.9 0.0 4.9e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EJS42632.1 - 5.9e-07 28.9 5.8 0.0014 17.8 3.0 2.6 2 1 1 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.13 EJS42632.1 - 1.4e-06 27.4 0.6 3.6e-06 26.0 0.4 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EJS42632.1 - 0.00026 20.3 0.7 0.0046 16.2 0.5 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein Response_reg PF00072.19 EJS42632.1 - 0.011 15.7 0.2 0.051 13.5 0.0 2.2 2 0 0 2 2 2 0 Response regulator receiver domain PK PF00224.16 EJS42632.1 - 0.048 12.2 0.2 3.2 6.2 0.0 2.6 3 0 0 3 3 3 0 Pyruvate kinase, barrel domain ThiG PF05690.9 EJS42632.1 - 0.099 11.7 1.5 0.12 11.4 0.2 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG WGG PF10273.4 EJS42633.1 - 2.3e-31 107.6 0.8 2.3e-31 107.6 0.5 1.8 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 DUF2457 PF10446.4 EJS42633.1 - 0.00057 18.7 15.6 0.00074 18.3 10.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Vfa1 PF08432.5 EJS42633.1 - 0.0029 17.6 3.3 0.0052 16.8 2.3 1.4 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 RXT2_N PF08595.6 EJS42633.1 - 0.041 13.6 8.7 0.069 12.9 6.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EJS42633.1 - 0.1 12.1 10.3 0.17 11.3 7.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EJS42633.1 - 0.15 12.3 15.4 0.48 10.7 10.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 EJS42633.1 - 0.43 10.1 8.0 0.62 9.6 5.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 EJS42633.1 - 0.68 9.5 10.4 1.2 8.8 7.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EJS42633.1 - 0.7 7.8 5.6 0.86 7.5 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein TT_ORF2 PF02957.10 EJS42633.1 - 0.84 10.3 5.2 1.5 9.5 3.6 1.3 1 0 0 1 1 1 0 TT viral ORF2 FAM176 PF14851.1 EJS42633.1 - 1.5 8.4 4.2 3 7.5 2.9 1.4 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.7 EJS42633.1 - 3.2 5.5 12.8 4 5.2 8.9 1.2 1 0 0 1 1 1 0 Nop14-like family Tom22 PF04281.8 EJS42633.1 - 4.5 6.7 10.2 11 5.4 7.1 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 NOA36 PF06524.7 EJS42633.1 - 9.5 5.3 11.4 12 4.9 7.9 1.1 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.2 EJS42634.1 - 4.2e-255 848.7 45.8 4.8e-255 848.5 31.7 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Aminotran_3 PF00202.16 EJS42635.1 - 1e-107 359.9 0.0 1.2e-107 359.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EJS42635.1 - 0.0002 20.5 0.0 0.00043 19.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EJS42635.1 - 0.091 11.6 0.0 0.16 10.8 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class I and II LSM PF01423.17 EJS42636.1 - 1.5e-19 69.2 0.1 1.9e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SH3_9 PF14604.1 EJS42636.1 - 0.1 12.1 0.2 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain MRP-L47 PF06984.8 EJS42637.1 - 8.9e-27 92.8 0.8 2.5e-26 91.3 0.1 2.1 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Sec39 PF08314.6 EJS42638.1 - 2.8e-161 537.9 16.9 3.2e-161 537.7 11.7 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF4206 PF13901.1 EJS42638.1 - 0.069 12.7 0.5 0.18 11.3 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Ribosomal_S3Ae PF01015.13 EJS42639.1 - 9.8e-80 266.4 7.2 1.1e-79 266.2 5.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EJS42639.1 - 0.061 12.6 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Inhibitor_I9 PF05922.11 EJS42639.1 - 0.079 13.5 0.1 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 Peptidase inhibitor I9 SpoVIF PF14069.1 EJS42639.1 - 0.28 10.9 2.6 5.2 6.8 0.6 2.4 1 1 1 2 2 2 0 Stage VI sporulation protein F BAH PF01426.13 EJS42640.1 - 1.7e-17 63.2 0.5 4.1e-17 62.0 0.3 1.7 1 0 0 1 1 1 1 BAH domain Fig1 PF12351.3 EJS42641.1 - 0.018 14.9 2.2 0.035 13.9 1.5 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF912 PF06024.7 EJS42641.1 - 0.064 13.3 0.3 0.22 11.6 0.2 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4234 PF14018.1 EJS42641.1 - 1.3 8.7 7.0 8.1 6.2 4.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) vATP-synt_AC39 PF01992.11 EJS42642.1 - 2.4e-86 289.9 0.0 2.7e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit FKBP_C PF00254.23 EJS42643.1 - 1.2e-27 95.6 0.1 8.6e-27 93.0 0.0 2.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF853 PF05872.7 EJS42643.1 - 2 6.6 4.9 3.4 5.8 3.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Daxx PF03344.10 EJS42643.1 - 2.4 6.5 49.3 0.08 11.4 19.2 2.1 2 0 0 2 2 2 0 Daxx Family Zn_clus PF00172.13 EJS42644.1 - 2.1e-08 33.9 11.1 3.8e-08 33.1 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BSP_II PF05432.6 EJS42644.1 - 0.0028 16.9 8.9 0.0047 16.2 6.2 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 EJS42644.1 - 0.011 13.8 3.0 0.02 12.9 2.1 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 EJS42644.1 - 0.013 15.6 6.0 0.013 15.6 4.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2890) FAM176 PF14851.1 EJS42644.1 - 0.14 11.8 5.1 0.46 10.1 3.6 1.9 1 0 0 1 1 1 0 FAM176 family Prothymosin PF03247.9 EJS42644.1 - 0.18 11.9 20.9 0.43 10.7 14.5 1.6 1 0 0 1 1 1 0 Prothymosin/parathymosin family Nucleoplasmin PF03066.10 EJS42644.1 - 1.4 8.4 11.4 2.5 7.6 7.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EJS42644.1 - 4.3 6.9 17.0 0.1 12.2 6.9 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region RGS PF00615.14 EJS42645.1 - 7.5e-19 67.9 0.6 3.6e-12 46.4 0.0 2.7 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.16 EJS42645.1 - 4.8e-14 51.8 0.0 2.8e-12 46.1 0.0 2.7 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TLD PF07534.11 EJS42645.1 - 0.052 13.5 3.0 0.3 11.0 0.3 2.7 2 0 0 2 2 2 0 TLD DUF1902 PF08972.6 EJS42645.1 - 0.18 11.3 0.1 0.4 10.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) DUF327 PF03885.8 EJS42645.1 - 0.19 11.5 2.1 0.39 10.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Peptidase_M16 PF00675.15 EJS42646.1 - 5.3e-53 178.7 0.0 1e-52 177.8 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EJS42646.1 - 6.7e-38 130.2 0.0 5.1e-37 127.3 0.0 2.2 2 1 1 3 3 3 1 Peptidase M16 inactive domain Sec10 PF07393.6 EJS42647.1 - 1.1e-207 691.5 34.3 1.5e-207 691.1 23.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 RTBV_P12 PF06361.6 EJS42647.1 - 0.028 14.6 0.8 0.34 11.1 0.3 2.9 2 1 1 3 3 3 0 Rice tungro bacilliform virus P12 protein ubiquitin PF00240.18 EJS42648.1 - 1.5e-34 117.2 0.9 2.7e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EJS42648.1 - 2.5e-27 94.4 1.7 4.5e-27 93.6 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EJS42648.1 - 5.1e-20 70.9 0.7 1e-19 69.9 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EJS42648.1 - 8.8e-06 25.8 0.2 3.9e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EJS42648.1 - 0.00012 21.8 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EJS42648.1 - 0.0013 18.5 0.3 0.0029 17.4 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EJS42648.1 - 0.0057 16.8 0.5 0.0075 16.4 0.4 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EJS42648.1 - 0.016 15.0 0.4 0.023 14.5 0.2 1.3 1 0 0 1 1 1 0 IBR domain Fer2_3 PF13085.1 EJS42648.1 - 0.042 13.6 0.3 0.083 12.7 0.1 1.6 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF2870 PF11069.3 EJS42648.1 - 0.059 13.4 0.2 0.13 12.3 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EJS42648.1 - 0.21 9.8 2.3 5.4 5.1 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain PRELI PF04707.9 EJS42649.1 - 1.3e-60 203.5 0.4 1.7e-60 203.1 0.3 1.2 1 0 0 1 1 1 1 PRELI-like family DUF3081 PF11280.3 EJS42649.1 - 0.11 12.0 0.1 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Clat_adaptor_s PF01217.15 EJS42650.1 - 1.4e-58 196.6 1.7 1.6e-58 196.4 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.15 EJS42651.1 - 1.8e-24 86.6 0.0 2.7e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 EJS42651.1 - 0.016 14.9 0.1 0.048 13.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) DUF1206 PF06724.6 EJS42652.1 - 0.11 12.2 0.3 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Iso_dh PF00180.15 EJS42653.1 - 2.3e-70 237.2 0.0 2.6e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YfmQ PF10787.4 EJS42653.1 - 0.013 14.8 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group DUF4355 PF14265.1 EJS42653.1 - 0.053 13.4 0.6 0.13 12.1 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF2543 PF10820.3 EJS42653.1 - 0.18 11.8 1.5 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) DKCLD PF08068.7 EJS42654.1 - 3e-30 103.9 0.1 1.3e-29 101.8 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EJS42654.1 - 3.8e-21 75.8 6.8 5.2e-20 72.1 0.0 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EJS42654.1 - 4.9e-19 67.8 1.0 9.7e-19 66.8 0.7 1.5 1 0 0 1 1 1 1 PUA domain GAGA_bind PF06217.7 EJS42654.1 - 0.19 11.6 21.7 0.28 11.1 15.1 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PBP PF01161.15 EJS42655.1 - 7.5e-33 113.4 0.2 1e-32 112.9 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.15 EJS42656.1 - 2.9e-30 105.0 0.0 3.5e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein S-AdoMet_synt_C PF02773.11 EJS42657.1 - 7e-75 249.3 0.2 1.1e-74 248.6 0.1 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EJS42657.1 - 5.8e-47 158.5 0.0 1e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EJS42657.1 - 2.9e-44 149.3 0.1 5.9e-44 148.3 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Ank PF00023.25 EJS42658.1 - 7.7e-13 47.5 1.6 3e-06 26.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EJS42658.1 - 1.4e-12 47.7 0.2 4.4e-05 23.7 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EJS42658.1 - 3.9e-12 45.1 1.7 1.6e-05 24.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EJS42658.1 - 7.4e-10 38.7 0.7 9e-07 28.9 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EJS42658.1 - 1.8e-08 34.6 3.1 0.0019 18.6 0.0 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) DUF3508 PF12018.3 EJS42658.1 - 0.08 11.9 6.6 0.082 11.8 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3508) IncA PF04156.9 EJS42658.1 - 0.18 11.3 7.7 0.41 10.2 5.3 1.5 1 0 0 1 1 1 0 IncA protein EMG1 PF03587.9 EJS42659.1 - 4.5e-77 257.9 0.0 5.3e-77 257.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PH PF00169.24 EJS42660.1 - 5e-07 29.8 0.6 8e-06 26.0 0.0 2.9 3 0 0 3 3 3 1 PH domain ABC_membrane PF00664.18 EJS42661.1 - 3.4e-60 203.8 6.3 4.3e-60 203.4 4.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EJS42661.1 - 3.4e-30 105.1 0.0 1.1e-29 103.5 0.0 1.9 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 EJS42661.1 - 2.8e-06 26.7 0.5 0.00025 20.3 0.4 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EJS42661.1 - 9.3e-06 25.7 0.1 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EJS42661.1 - 0.00016 21.7 1.5 0.034 14.1 0.2 2.8 2 2 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EJS42661.1 - 0.00024 21.9 0.0 0.00053 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EJS42661.1 - 0.00047 20.2 0.0 0.0026 17.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EJS42661.1 - 0.0015 18.7 0.0 0.024 14.8 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EJS42661.1 - 0.0039 17.0 0.0 0.044 13.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EJS42661.1 - 0.0066 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EJS42661.1 - 0.007 15.8 0.0 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EJS42661.1 - 0.0099 15.7 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EJS42661.1 - 0.019 14.1 0.0 0.089 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EJS42661.1 - 0.022 14.5 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EJS42661.1 - 0.029 14.6 0.0 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EJS42661.1 - 0.04 13.8 0.5 0.21 11.5 0.4 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.24 EJS42661.1 - 0.067 12.6 0.1 1.1 8.7 0.1 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase IstB_IS21 PF01695.12 EJS42661.1 - 0.067 12.5 0.0 7.6 5.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 EJS42661.1 - 0.093 12.1 0.0 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Glyco_transf_28 PF03033.15 EJS42662.1 - 1.6e-31 108.9 0.0 3.7e-31 107.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 EJS42662.1 - 1.4e-20 72.5 3.5 3.8e-16 58.3 0.4 3.2 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.13 EJS42662.1 - 1.5e-09 37.0 0.0 3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 EJS42662.1 - 7.9e-09 35.6 1.7 7.9e-09 35.6 1.2 2.9 3 0 0 3 3 3 1 PH domain Glyco_trans_1_3 PF13528.1 EJS42662.1 - 0.00055 19.2 0.0 0.0074 15.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 1 PH_11 PF15413.1 EJS42662.1 - 0.016 15.4 1.6 0.2 11.9 1.0 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain Glyco_trans_4_4 PF13579.1 EJS42662.1 - 0.071 13.2 0.0 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain MMR1 PF08505.5 EJS42663.1 - 1e-60 205.7 10.7 1e-60 205.7 7.4 2.5 2 1 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein Myb_DNA-bind_4 PF13837.1 EJS42663.1 - 0.22 11.6 1.9 1.2 9.3 0.3 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF573 PF04504.9 EJS42663.1 - 0.33 11.2 4.1 0.29 11.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF573 P_C PF06640.6 EJS42663.1 - 0.41 10.5 6.0 0.046 13.7 0.5 2.0 2 0 0 2 2 2 0 P protein C-terminus Allexi_40kDa PF05549.6 EJS42663.1 - 2.1 7.5 12.0 4.8 6.4 1.8 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein eIF3_subunit PF08597.5 EJS42664.1 - 2.8e-62 210.5 18.8 7.7e-62 209.0 13.0 1.6 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit PRELI PF04707.9 EJS42665.1 - 6.2e-50 168.8 0.1 7.3e-50 168.6 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family NMT PF01233.14 EJS42667.1 - 4.8e-87 289.6 0.1 9e-87 288.7 0.1 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EJS42667.1 - 3.1e-77 258.2 1.1 3.1e-77 258.2 0.8 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EJS42667.1 - 4.8e-07 29.6 0.0 7.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EJS42667.1 - 0.021 15.0 0.0 0.09 12.9 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain WD40 PF00400.27 EJS42668.1 - 1.1e-12 47.2 6.0 1.2e-06 28.1 0.6 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.3 EJS42668.1 - 0.032 12.3 2.7 0.068 11.3 0.6 2.1 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EJS42668.1 - 0.1 12.9 0.1 2 8.7 0.0 3.1 4 0 0 4 4 4 0 PQQ-like domain Nop PF01798.13 EJS42669.1 - 9.4e-61 203.5 0.1 1.8e-60 202.6 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EJS42669.1 - 5.8e-27 93.2 0.1 1.3e-26 92.1 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EJS42669.1 - 1.9e-23 82.3 0.5 1.9e-23 82.3 0.4 2.7 2 1 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EJS42669.1 - 0.0033 17.1 44.4 0.0057 16.3 30.8 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 PcfK PF14058.1 EJS42669.1 - 0.39 10.8 28.0 0.62 10.1 19.4 1.3 1 0 0 1 1 1 0 PcfK-like protein GAGA_bind PF06217.7 EJS42669.1 - 0.47 10.3 17.0 0.73 9.7 11.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 EJS42669.1 - 0.58 9.9 9.6 0.93 9.2 6.7 1.5 1 0 0 1 1 1 0 DDHD domain MIP-T3 PF10243.4 EJS42669.1 - 1.6 7.1 37.8 2.3 6.5 26.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RR_TM4-6 PF06459.7 EJS42669.1 - 3.2 7.5 23.9 5.2 6.8 16.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Prefoldin_2 PF01920.15 EJS42670.1 - 4.1e-25 87.5 11.8 4.4e-25 87.4 8.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4201 PF13870.1 EJS42670.1 - 0.006 16.0 0.8 0.006 16.0 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF1192 PF06698.6 EJS42670.1 - 0.029 14.1 0.8 0.029 14.1 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Prefoldin PF02996.12 EJS42670.1 - 0.074 12.7 6.5 0.14 11.8 4.5 1.5 1 1 0 1 1 1 0 Prefoldin subunit IMD PF08397.6 EJS42670.1 - 0.1 11.8 2.4 0.2 10.9 1.7 1.6 1 1 0 1 1 1 0 IRSp53/MIM homology domain Tup_N PF08581.5 EJS42670.1 - 0.11 12.7 7.3 0.21 11.7 0.1 2.5 2 1 0 2 2 2 0 Tup N-terminal ADIP PF11559.3 EJS42670.1 - 0.15 11.9 0.3 0.15 11.9 0.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 EJS42670.1 - 0.18 11.4 9.6 0.82 9.3 0.9 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF3166 PF11365.3 EJS42670.1 - 0.22 11.9 6.2 0.19 12.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Bcr-Abl_Oligo PF09036.5 EJS42670.1 - 0.28 11.1 1.5 0.39 10.6 1.0 1.5 1 1 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DMPK_coil PF08826.5 EJS42670.1 - 0.39 10.6 10.9 0.39 10.6 1.7 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like CENP-F_leu_zip PF10473.4 EJS42670.1 - 0.4 10.5 10.8 0.84 9.4 1.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 EJS42670.1 - 0.44 9.4 4.4 0.55 9.1 3.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_3 PF13758.1 EJS42670.1 - 0.49 10.2 5.6 22 4.9 3.8 2.3 1 1 0 1 1 1 0 Prefoldin subunit Macoilin PF09726.4 EJS42670.1 - 0.7 8.0 6.7 0.8 7.9 4.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1664 PF07889.7 EJS42670.1 - 0.77 9.5 2.7 1 9.2 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FliJ PF02050.11 EJS42670.1 - 0.97 9.5 10.5 2.7 8.0 0.5 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein DUF342 PF03961.8 EJS42670.1 - 1.2 7.4 6.6 1.5 7.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) YgaB PF14182.1 EJS42670.1 - 1.3 9.2 12.0 0.27 11.5 3.7 2.1 1 1 1 2 2 2 0 YgaB-like protein Med4 PF10018.4 EJS42670.1 - 1.7 8.0 6.3 0.12 11.7 0.4 1.8 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3847 PF12958.2 EJS42670.1 - 1.8 8.3 11.5 0.11 12.3 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Tropomyosin_1 PF12718.2 EJS42670.1 - 1.8 8.4 13.9 10 5.9 9.6 1.9 1 1 0 1 1 1 0 Tropomyosin like DUF641 PF04859.7 EJS42670.1 - 3.8 7.2 8.3 1.6 8.4 1.8 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Med9 PF07544.8 EJS42670.1 - 4.5 7.0 8.5 0.28 10.9 1.9 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EJS42670.1 - 6.7 6.2 15.4 14 5.1 10.7 1.5 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 EJS42670.1 - 8 5.4 12.0 5.4 5.9 6.5 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 COQ9 PF08511.6 EJS42671.1 - 5.8e-19 67.3 0.5 5.8e-19 67.3 0.3 1.9 1 1 1 2 2 2 1 COQ9 zf-Mss51 PF13824.1 EJS42672.1 - 5.7e-18 64.5 0.8 1.1e-17 63.5 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 EJS42672.1 - 0.0082 15.6 0.0 0.025 14.1 0.0 1.8 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF1713 PF08213.6 EJS42673.1 - 3.4e-12 45.7 24.9 5.1e-12 45.1 17.2 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) TATR PF03430.8 EJS42673.1 - 0.064 11.9 1.5 0.065 11.8 1.0 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Heme_oxygenase PF01126.15 EJS42674.1 - 1.9e-11 43.9 0.3 6.6e-11 42.1 0.2 1.9 1 1 0 1 1 1 1 Heme oxygenase Sel1 PF08238.7 EJS42675.1 - 2.9e-20 72.2 15.4 4.2e-05 24.0 0.0 8.6 9 0 0 9 9 9 4 Sel1 repeat TPR_1 PF00515.23 EJS42675.1 - 2.5e-05 23.6 14.2 0.32 10.6 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EJS42675.1 - 0.00014 21.4 14.3 0.18 11.8 0.7 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EJS42675.1 - 0.00031 20.3 17.2 0.098 12.4 0.1 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EJS42675.1 - 0.0005 19.6 10.8 0.38 10.6 0.2 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EJS42675.1 - 0.0013 18.3 11.9 0.095 12.3 1.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_6 PF13174.1 EJS42675.1 - 0.0026 18.1 6.0 4 8.1 0.4 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EJS42675.1 - 0.041 13.8 18.0 0.14 12.0 0.0 6.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.1 EJS42675.1 - 0.53 11.0 10.0 3.6 8.3 0.1 4.9 4 1 2 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 EJS42676.1 - 5.5e-44 146.5 20.2 4.6e-10 38.9 0.4 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EJS42676.1 - 0.0052 16.5 6.2 1.1 8.9 0.9 3.7 1 1 3 4 4 4 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 EJS42676.1 - 0.029 14.1 0.1 8 6.3 0.0 3.4 4 0 0 4 4 4 0 YmzC-like protein PNP_UDP_1 PF01048.15 EJS42677.1 - 4.1e-43 147.0 0.0 4.9e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Cyclin_N PF00134.18 EJS42678.1 - 5.5e-41 139.0 0.3 1.2e-40 138.0 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EJS42678.1 - 6.5e-25 87.3 0.0 1.8e-24 85.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Tubulin PF00091.20 EJS42679.1 - 2.7e-69 233.2 0.0 4.3e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EJS42679.1 - 1e-28 99.8 1.0 2.1e-28 98.8 0.3 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EJS42679.1 - 5.3e-05 23.2 0.0 9.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain FAD_binding_8 PF08022.7 EJS42680.1 - 5.2e-24 84.1 0.0 1.2e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EJS42680.1 - 7e-22 78.0 0.0 1.4e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EJS42680.1 - 7.3e-21 74.5 8.7 7.3e-21 74.5 6.0 2.8 2 1 0 2 2 2 1 Ferric reductase like transmembrane component CFEM PF05730.6 EJS42680.1 - 0.027 14.2 3.4 0.052 13.3 2.3 1.3 1 0 0 1 1 1 0 CFEM domain DUF4399 PF14347.1 EJS42680.1 - 0.029 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) DUF4405 PF14358.1 EJS42680.1 - 0.032 14.3 0.4 0.032 14.3 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Pro_isomerase PF00160.16 EJS42681.1 - 9.6e-45 152.5 0.2 1.6e-44 151.8 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.23 EJS42681.1 - 1.5e-06 27.5 1.9 8.1e-06 25.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EJS42681.1 - 4.8e-05 22.9 4.9 0.00082 18.9 0.4 2.5 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EJS42681.1 - 0.00015 21.4 2.0 0.0014 18.3 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EJS42681.1 - 0.14 12.7 2.9 0.5 10.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EJS42681.1 - 0.45 10.4 11.2 1 9.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat VIT1 PF01988.14 EJS42682.1 - 2.1e-57 194.0 1.2 2.6e-57 193.7 0.8 1.1 1 0 0 1 1 1 1 VIT family Rsa3 PF14615.1 EJS42683.1 - 5.6e-19 67.1 0.1 9.6e-19 66.4 0.1 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 SR-25 PF10500.4 EJS42683.1 - 0.00027 20.5 20.0 0.00037 20.0 13.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3945 PF13101.1 EJS42683.1 - 0.049 12.9 0.4 0.2 11.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) DUF3827 PF12877.2 EJS42683.1 - 0.91 7.5 15.3 1.1 7.2 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Nop14 PF04147.7 EJS42683.1 - 1.2 6.9 20.9 1.5 6.6 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 EJS42684.1 - 4.1e-64 210.3 9.4 8.9e-09 34.9 0.1 11.2 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.6 EJS42684.1 - 6.2e-49 165.2 1.8 1.2e-48 164.3 1.3 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EJS42684.1 - 8.5e-08 30.7 6.0 0.054 11.6 0.1 5.9 4 1 2 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EJS42684.1 - 2.9e-05 23.0 6.9 1 8.0 0.1 4.3 2 1 1 4 4 4 3 Nup133 N terminal like Svf1 PF08622.5 EJS42686.1 - 1e-100 336.8 0.3 1.3e-100 336.5 0.2 1.1 1 0 0 1 1 1 1 Svf1-like FAD_binding_6 PF00970.19 EJS42686.1 - 0.033 14.3 0.0 0.098 12.7 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Ras PF00071.17 EJS42688.1 - 9.4e-51 171.4 0.0 1.1e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS42688.1 - 4.8e-14 52.8 0.0 6.4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS42688.1 - 5.5e-07 28.9 0.0 7.3e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Aminotran_5 PF00266.14 EJS42689.1 - 2.4e-14 52.8 0.0 4.6e-14 51.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Topoisom_bac PF01131.15 EJS42690.1 - 5.5e-92 308.6 0.0 7.9e-92 308.1 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EJS42690.1 - 6.5e-23 80.5 0.0 1.3e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain FHA PF00498.21 EJS42691.1 - 4.5e-17 61.9 2.3 3.4e-16 59.1 0.2 3.0 3 0 0 3 3 3 1 FHA domain MS_channel PF00924.13 EJS42691.1 - 0.12 11.7 3.6 5.4 6.2 0.3 2.8 2 0 0 2 2 2 0 Mechanosensitive ion channel FlxA PF14282.1 EJS42691.1 - 5.1 7.0 10.1 15 5.6 7.0 1.8 1 0 0 1 1 1 0 FlxA-like protein BPL_LplA_LipB PF03099.14 EJS42692.1 - 9.8e-21 74.0 0.0 1.6e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PI3Ka PF00613.15 EJS42693.1 - 7e-77 256.7 3.3 1.1e-76 256.1 2.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EJS42693.1 - 1.4e-47 162.1 0.0 4.3e-46 157.2 0.0 2.8 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EJS42693.1 - 8e-28 97.0 0.4 2.2e-27 95.6 0.3 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 AlcCBM31 PF11606.3 EJS42693.1 - 0.11 12.4 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein DUF221 PF02714.10 EJS42694.1 - 4.4e-100 334.7 20.8 8.8e-100 333.7 14.4 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EJS42694.1 - 8.2e-43 145.6 1.6 8.2e-43 145.6 1.1 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EJS42694.1 - 2.6e-14 53.5 0.0 4.8e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Arv1 PF04161.8 EJS42695.1 - 2.4e-81 272.6 12.6 2.4e-81 272.6 8.8 1.6 2 0 0 2 2 2 1 Arv1-like family ATP_bind_1 PF03029.12 EJS42696.1 - 2.6e-87 292.3 0.0 3e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EJS42696.1 - 7.4e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 EJS42696.1 - 0.00011 23.0 0.0 0.00032 21.5 0.0 1.7 1 1 0 2 2 1 1 AAA domain ArgK PF03308.11 EJS42696.1 - 0.00019 20.3 0.1 0.00047 19.0 0.0 1.5 2 0 0 2 2 2 1 ArgK protein MMR_HSR1 PF01926.18 EJS42696.1 - 0.00029 20.7 0.0 0.00051 19.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase KAP_NTPase PF07693.9 EJS42696.1 - 0.002 17.2 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain ABC_tran PF00005.22 EJS42696.1 - 0.0022 18.2 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter MobB PF03205.9 EJS42696.1 - 0.0031 17.2 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EJS42696.1 - 0.0043 17.2 0.0 0.014 15.5 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.1 EJS42696.1 - 0.0074 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EJS42696.1 - 0.018 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 EJS42696.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF258 PF03193.11 EJS42696.1 - 0.02 14.0 0.0 0.05 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EJS42696.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EJS42696.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 EJS42696.1 - 0.028 13.6 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family GTP_EFTU PF00009.22 EJS42696.1 - 0.031 13.7 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.13 EJS42696.1 - 0.032 13.2 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_30 PF13604.1 EJS42696.1 - 0.046 13.2 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EJS42696.1 - 0.048 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PPV_E1_C PF00519.12 EJS42696.1 - 0.068 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_18 PF13238.1 EJS42696.1 - 0.07 13.4 0.1 0.19 12.0 0.0 1.8 2 1 0 2 2 1 0 AAA domain NACHT PF05729.7 EJS42696.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EJS42696.1 - 0.077 12.9 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 EJS42696.1 - 0.083 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 EJS42696.1 - 0.084 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 EJS42696.1 - 0.088 12.2 0.0 0.63 9.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EJS42696.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain SRP54 PF00448.17 EJS42696.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EJS42696.1 - 0.12 12.0 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EJS42696.1 - 0.22 10.3 1.1 0.85 8.4 0.0 2.0 1 1 0 2 2 2 0 NB-ARC domain Peptidase_M24 PF00557.19 EJS42697.1 - 1.6e-49 168.3 0.7 2e-49 167.9 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 zf-DHHC PF01529.15 EJS42698.1 - 7.2e-35 119.9 8.2 7.2e-35 119.9 5.7 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase SDF PF00375.13 EJS42698.1 - 0.0076 15.0 0.1 0.0076 15.0 0.0 1.9 3 0 0 3 3 3 1 Sodium:dicarboxylate symporter family Pro_dh PF01619.13 EJS42700.1 - 1.8e-79 266.9 0.0 2.5e-79 266.4 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase ATP_bind_4 PF01902.12 EJS42701.1 - 3.1e-36 124.8 0.0 4.6e-35 120.9 0.0 2.5 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 EJS42701.1 - 1.9e-18 66.3 0.0 1.3e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP Dabb PF07876.7 EJS42701.1 - 0.037 14.4 0.1 2.3 8.7 0.0 2.8 3 0 0 3 3 3 0 Stress responsive A/B Barrel Domain Coat_X PF07552.6 EJS42701.1 - 0.16 11.7 0.7 0.51 10.1 0.5 1.8 1 0 0 1 1 1 0 Spore Coat Protein X and V domain Glyco_hydro_81 PF03639.8 EJS42702.1 - 3.6e-296 983.8 12.6 4.2e-296 983.5 8.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 DUF413 PF04219.7 EJS42703.1 - 0.064 12.9 0.3 6.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF Spermine_synth PF01564.12 EJS42704.1 - 3.8e-92 307.6 0.0 6.9e-92 306.8 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_23 PF13489.1 EJS42704.1 - 6.9e-06 25.8 0.0 2.2e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS42704.1 - 1.2e-05 25.8 0.0 2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EJS42704.1 - 0.0015 18.5 0.0 0.0036 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EJS42704.1 - 0.0017 18.7 0.0 0.0037 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EJS42704.1 - 0.0041 16.7 0.0 0.0072 15.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EJS42704.1 - 0.0058 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Pep3_Vps18 PF05131.9 EJS42705.1 - 9.9e-45 151.5 0.3 3.1e-44 149.9 0.2 1.9 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EJS42705.1 - 3.4e-17 62.3 6.4 3.4e-17 62.3 4.4 4.2 5 0 0 5 5 5 2 Region in Clathrin and VPS Vps39_2 PF10367.4 EJS42705.1 - 3.4e-05 23.9 3.6 6.3e-05 23.1 0.2 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 EJS42705.1 - 8.2e-05 22.3 3.7 0.00016 21.4 2.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EJS42705.1 - 0.002 17.8 2.9 0.0045 16.6 2.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EJS42705.1 - 0.0059 16.6 2.8 0.015 15.3 2.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EJS42705.1 - 0.075 12.7 0.9 0.17 11.6 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNHCP PF12647.2 EJS42705.1 - 0.19 11.6 0.5 0.36 10.6 0.4 1.4 1 0 0 1 1 1 0 RNHCP domain zf-C3HC4 PF00097.20 EJS42705.1 - 0.4 10.3 2.3 1 9.0 1.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2415 PF10313.4 EJS42706.1 - 5.2e-21 74.0 1.1 1.1e-20 72.9 0.7 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Str_synth PF03088.11 EJS42706.1 - 0.012 15.6 0.1 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase Stm1_N PF09598.5 EJS42707.1 - 1e-18 67.7 2.8 1e-18 67.7 1.9 4.7 3 1 0 3 3 3 1 Stm1 Mem_trans PF03547.13 EJS42708.1 - 5.2e-52 176.4 6.5 2.4e-29 101.8 1.7 2.0 2 0 0 2 2 2 2 Membrane transport protein Reticulon PF02453.12 EJS42708.1 - 0.33 10.5 10.1 0.58 9.7 1.5 2.6 2 0 0 2 2 2 0 Reticulon AMP-binding PF00501.23 EJS42709.1 - 6.6e-88 294.8 0.1 8.9e-88 294.4 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EJS42709.1 - 2.1e-18 67.0 0.0 5.9e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNase_H2_suC PF08615.6 EJS42710.1 - 0.086 12.6 0.1 0.65 9.8 0.1 2.1 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) BTB_2 PF02214.17 EJS42711.1 - 6.7e-07 29.4 2.8 0.011 15.9 0.1 2.9 2 1 0 2 2 2 2 BTB/POZ domain SLS PF14611.1 EJS42711.1 - 0.011 15.1 0.2 0.023 14.1 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator IGFBP PF00219.13 EJS42711.1 - 0.8 10.2 6.1 1.9 9.1 4.2 1.6 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Redoxin PF08534.5 EJS42712.1 - 4.6e-32 110.5 0.3 5.1e-32 110.4 0.2 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EJS42712.1 - 1.4e-08 34.4 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Alkyl_sulf_C PF14864.1 EJS42712.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Flocculin_t3 PF13928.1 EJS42713.1 - 3.6e-15 55.8 19.3 3.6e-15 55.8 13.3 3.0 3 1 0 3 3 3 1 Flocculin type 3 repeat zf-piccolo PF05715.8 EJS42713.1 - 4.6 7.3 5.4 4.9 7.2 0.3 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger Pkinase PF00069.20 EJS42714.1 - 1.7e-69 233.8 0.0 2.2e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42714.1 - 1.5e-30 106.1 0.0 2.2e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EJS42714.1 - 1.6e-05 24.0 0.1 5.4e-05 22.3 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS42714.1 - 0.00027 20.7 0.4 0.0018 18.0 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EJS42714.1 - 0.0026 16.7 0.0 0.065 12.1 0.0 2.2 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EJS42714.1 - 0.089 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family CPSF100_C PF13299.1 EJS42715.1 - 1.4e-28 100.0 0.9 1.4e-28 100.0 0.6 3.4 2 2 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EJS42715.1 - 1.2e-09 38.1 0.8 5.7e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain HAT PF02184.11 EJS42716.1 - 2.3e-22 78.4 27.9 1e-08 34.7 0.1 8.8 8 0 0 8 8 8 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EJS42716.1 - 6.5e-17 60.5 0.2 0.024 15.2 0.0 7.9 6 2 2 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EJS42716.1 - 6e-08 33.1 1.4 0.66 10.7 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EJS42716.1 - 2.9e-06 27.5 0.0 1.2 9.5 0.0 5.2 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EJS42716.1 - 9.3e-05 22.3 0.9 0.028 14.5 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EJS42716.1 - 0.0012 18.4 6.8 1.1 8.9 0.0 6.1 5 2 1 6 6 6 1 TPR repeat U3_assoc_6 PF08640.6 EJS42716.1 - 0.0024 17.6 1.2 0.0024 17.6 0.8 5.6 4 1 2 6 6 6 1 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.1 EJS42716.1 - 0.013 15.4 5.6 12 5.9 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 EJS42716.1 - 0.038 13.8 19.7 1.2 9.2 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.1 EJS42716.1 - 2.2 8.2 12.2 18 5.3 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat GATase PF00117.23 EJS42717.1 - 1.7e-13 50.4 0.1 2.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EJS42717.1 - 0.0027 17.1 0.0 0.0078 15.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 STb_secrete PF09075.5 EJS42717.1 - 0.022 14.6 0.1 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory WD40 PF00400.27 EJS42718.1 - 1.7e-69 227.3 32.8 1.6e-10 40.4 0.2 11.0 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 EJS42718.1 - 2.5e-23 82.0 0.4 4.9e-23 81.1 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EJS42718.1 - 5.1e-09 34.8 11.9 0.00047 18.4 0.1 5.3 4 2 0 5 5 5 3 Nucleoporin Nup120/160 Hira PF07569.6 EJS42718.1 - 0.0023 17.2 4.2 3.5 6.7 0.0 5.2 6 0 0 6 6 6 2 TUP1-like enhancer of split eIF2A PF08662.6 EJS42718.1 - 0.0085 15.8 2.6 0.22 11.2 0.0 4.1 4 2 2 6 6 6 1 Eukaryotic translation initiation factor eIF2A tRNA_SAD PF07973.9 EJS42718.1 - 0.24 11.3 1.1 14 5.6 0.1 2.5 2 0 0 2 2 2 0 Threonyl and Alanyl tRNA synthetase second additional domain Zip PF02535.17 EJS42719.1 - 1.2e-66 224.9 2.2 1.6e-66 224.4 1.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.8 EJS42719.1 - 0.075 12.2 1.5 0.12 11.5 0.5 1.7 2 0 0 2 2 2 0 UNC-50 family Cation_ATPase_C PF00689.16 EJS42719.1 - 1.3 8.4 9.3 4.9 6.6 1.9 2.5 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus zf-C2H2 PF00096.21 EJS42720.1 - 4.3e-10 39.3 14.8 0.00037 20.6 0.6 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS42720.1 - 4.1e-06 26.7 11.9 0.03 14.6 0.5 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EJS42720.1 - 0.0014 18.8 18.3 0.0057 16.8 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain Bunya_G2 PF03563.8 EJS42720.1 - 0.0019 17.1 0.6 0.0028 16.5 0.4 1.2 1 0 0 1 1 1 1 Bunyavirus glycoprotein G2 zf-TRAF PF02176.13 EJS42720.1 - 0.053 13.9 0.5 0.15 12.5 0.3 1.7 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 EJS42720.1 - 0.098 12.8 0.2 9.8 6.4 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA_23 PF13476.1 EJS42720.1 - 0.25 11.6 9.8 0.24 11.6 5.7 1.7 2 0 0 2 2 2 0 AAA domain HVSL PF09749.4 EJS42721.1 - 1.8e-38 131.9 0.2 2.3e-38 131.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Wx5_PLAF3D7 PF09688.5 EJS42721.1 - 0.073 13.0 0.2 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) Choline_kinase PF01633.15 EJS42722.1 - 1.9e-70 236.7 0.2 2.6e-70 236.3 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EJS42722.1 - 1e-15 56.9 0.1 2.1e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EJS42722.1 - 9.5e-09 35.3 0.0 0.00011 22.0 0.0 2.7 2 1 0 2 2 2 2 Phosphotransferase enzyme family TPP_enzyme_M PF00205.17 EJS42723.1 - 9.7e-37 125.7 0.0 3.8e-36 123.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 EJS42723.1 - 4.2e-34 117.4 0.0 6.8e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EJS42723.1 - 1.5e-14 53.8 0.0 2.9e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EJS42723.1 - 0.004 16.7 0.0 0.009 15.5 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit OCC1 PF15506.1 EJS42723.1 - 0.16 11.8 0.2 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 OCC1 family Slx4 PF09494.5 EJS42724.1 - 1.2e-14 53.7 0.5 3.1e-14 52.4 0.1 1.9 2 0 0 2 2 2 1 Slx4 endonuclease zf-CCCH PF00642.19 EJS42725.1 - 2.2e-17 62.2 16.0 3.9e-10 39.1 1.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EJS42725.1 - 0.088 12.8 15.8 0.15 12.0 0.5 3.0 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type UvsW PF11637.3 EJS42725.1 - 0.2 11.3 0.8 3 7.5 0.2 2.7 2 0 0 2 2 2 0 ATP-dependant DNA helicase UvsW Methyltransf_16 PF10294.4 EJS42726.1 - 2.2e-07 30.5 0.0 0.00064 19.2 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase Mito_fiss_reg PF05308.6 EJS42726.1 - 0.065 12.5 3.0 0.12 11.7 2.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EJS42726.1 - 0.069 12.4 1.3 0.11 11.8 0.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Nha1_C PF08619.5 EJS42727.1 - 5.5e-92 309.3 35.5 7.7e-92 308.8 24.6 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EJS42727.1 - 1e-79 267.8 25.5 1.2e-79 267.5 17.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SLS PF14611.1 EJS42728.1 - 7e-35 120.3 0.8 1.6e-34 119.1 0.6 1.7 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator DUF3437 PF11919.3 EJS42728.1 - 0.039 13.6 0.1 0.81 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Gaa1 PF04114.9 EJS42730.1 - 4.8e-183 609.4 11.2 6.1e-183 609.1 7.8 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Aminotran_1_2 PF00155.16 EJS42731.1 - 4.4e-36 124.5 0.0 7e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EJS42731.1 - 0.00024 20.3 0.0 0.00043 19.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase MTD PF01993.13 EJS42731.1 - 0.14 11.1 0.2 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase DnaJ PF00226.26 EJS42732.1 - 1.4e-23 82.3 2.5 2.4e-23 81.6 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EJS42732.1 - 3.3e-17 62.1 0.1 9.5e-16 57.4 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EJS42732.1 - 4.6e-10 39.4 11.1 2.3e-08 33.9 8.5 2.6 1 1 2 3 3 3 3 DnaJ central domain NOB1_Zn_bind PF08772.6 EJS42732.1 - 0.0021 17.8 0.3 0.0067 16.2 0.2 1.8 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Cytochrome_C7 PF14522.1 EJS42732.1 - 0.042 13.4 3.1 0.11 12.1 2.2 1.7 1 0 0 1 1 1 0 Cytochrome c7 Cytochrome_C554 PF13435.1 EJS42732.1 - 0.39 10.7 4.9 1.6 8.7 3.4 2.0 1 1 0 1 1 1 0 Cytochrome c554 and c-prime zf-CHY PF05495.7 EJS42732.1 - 0.71 10.0 6.9 2.7 8.2 2.2 2.4 1 1 1 2 2 2 0 CHY zinc finger Cytochrom_c3_2 PF14537.1 EJS42732.1 - 0.98 9.8 9.4 0.36 11.1 4.1 2.1 2 1 0 2 2 2 0 Cytochrome c3 Sulfate_transp PF00916.15 EJS42733.1 - 6.1e-92 307.5 1.3 6.1e-92 307.5 0.9 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EJS42733.1 - 1.9e-30 104.3 3.4 1.9e-30 104.3 2.3 2.1 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EJS42733.1 - 0.00014 21.2 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EJS42733.1 - 0.012 15.6 0.1 0.03 14.3 0.1 1.6 1 0 0 1 1 1 0 STAS domain Pkinase PF00069.20 EJS42735.1 - 3e-70 236.3 1.2 8.4e-70 234.8 0.8 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42735.1 - 2.7e-39 134.8 0.5 3.6e-38 131.1 0.3 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EJS42735.1 - 3.1e-19 68.1 0.0 5.8e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EJS42735.1 - 4.5e-06 25.8 0.0 8e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EJS42735.1 - 9e-05 21.6 0.0 0.0002 20.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS42735.1 - 0.0064 16.2 0.0 0.035 13.8 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EJS42735.1 - 0.012 14.8 0.2 0.024 13.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EJS42735.1 - 0.02 14.2 0.0 0.02 14.2 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Abhydrolase_6 PF12697.2 EJS42736.1 - 6.7e-22 78.4 0.0 1.1e-21 77.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EJS42736.1 - 1.4e-17 64.0 0.0 4.1e-16 59.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EJS42736.1 - 4.7e-14 52.3 0.0 3.4e-13 49.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EJS42736.1 - 1.5e-07 30.8 0.1 0.0027 16.8 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 EJS42736.1 - 1.9e-06 27.6 0.0 0.006 16.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ndr PF03096.9 EJS42736.1 - 1.5e-05 23.5 0.0 0.0042 15.6 0.0 2.5 2 1 0 2 2 2 2 Ndr family BAAT_C PF08840.6 EJS42736.1 - 0.00016 21.4 0.0 0.077 12.6 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EJS42736.1 - 0.0005 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF2305 PF10230.4 EJS42736.1 - 0.0024 17.3 0.0 0.0073 15.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EJS42736.1 - 0.007 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 EJS42736.1 - 0.022 14.0 0.0 0.78 8.9 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF676 PF05057.9 EJS42736.1 - 0.023 14.0 0.0 0.058 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.15 EJS42736.1 - 0.035 14.3 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain Chlorophyllase2 PF12740.2 EJS42736.1 - 0.044 12.6 0.0 0.28 10.0 0.0 2.2 2 0 0 2 2 2 0 Chlorophyllase enzyme Lipase_3 PF01764.20 EJS42736.1 - 0.047 13.3 0.0 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 EJS42736.1 - 0.048 12.4 0.0 0.08 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Ser_hydrolase PF06821.8 EJS42736.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase adh_short PF00106.20 EJS42737.1 - 0.00072 19.5 0.0 0.058 13.3 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase Peptidase_C47 PF05543.8 EJS42737.1 - 0.027 13.8 0.1 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 Staphopain peptidase C47 CDC45 PF02724.9 EJS42738.1 - 2.7e-220 732.6 1.5 3.1e-220 732.4 1.0 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF2201_N PF13203.1 EJS42738.1 - 0.22 10.6 1.5 0.39 9.8 1.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain SDA1 PF05285.7 EJS42738.1 - 1.1 8.4 22.8 0.075 12.2 9.1 2.1 2 0 0 2 2 2 0 SDA1 tRNA_int_endo PF01974.12 EJS42739.1 - 9.7e-22 76.5 0.5 2.3e-21 75.3 0.3 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Psu PF07455.6 EJS42739.1 - 0.047 13.1 0.3 0.56 9.6 1.0 1.9 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) tRNA_int_endo_N PF02778.9 EJS42739.1 - 0.056 12.9 0.0 0.68 9.5 0.0 2.5 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain RNA_pol_Rpb1_5 PF04998.12 EJS42739.1 - 0.14 11.4 0.3 0.19 10.9 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 AAA_5 PF07728.9 EJS42740.1 - 3e-123 406.0 0.4 1.2e-20 73.7 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EJS42740.1 - 1.1e-31 109.2 0.0 3.2e-10 39.7 0.0 8.2 8 0 0 8 8 8 5 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EJS42740.1 - 9.4e-27 93.8 2.8 0.00023 21.3 0.0 8.0 8 0 0 8 8 7 5 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EJS42740.1 - 1.8e-21 76.6 0.2 0.00054 20.0 0.0 7.3 7 0 0 7 7 6 3 Sigma-54 interaction domain AAA_17 PF13207.1 EJS42740.1 - 8.8e-21 74.9 23.2 0.0085 16.9 0.0 8.9 8 1 0 9 9 6 6 AAA domain Sigma54_activat PF00158.21 EJS42740.1 - 9.8e-18 64.1 0.4 0.0025 17.3 0.0 5.8 5 0 0 5 5 5 4 Sigma-54 interaction domain AAA_22 PF13401.1 EJS42740.1 - 2.3e-17 63.3 7.1 0.029 14.4 0.9 8.6 6 2 0 6 6 6 4 AAA domain AAA_16 PF13191.1 EJS42740.1 - 3.1e-17 63.1 7.6 0.0041 17.1 0.0 8.4 9 1 0 9 9 6 4 AAA ATPase domain AAA_33 PF13671.1 EJS42740.1 - 3.2e-16 59.5 0.0 0.0058 16.5 0.2 7.2 6 2 0 6 6 6 2 AAA domain T2SE PF00437.15 EJS42740.1 - 2e-15 56.4 6.4 0.0059 15.5 0.0 6.0 6 0 0 6 6 6 4 Type II/IV secretion system protein AAA_14 PF13173.1 EJS42740.1 - 2.4e-14 53.3 18.1 0.00025 20.9 0.0 10.0 11 1 1 12 12 9 3 AAA domain UPF0079 PF02367.12 EJS42740.1 - 5.7e-14 51.8 4.1 0.073 12.7 0.1 7.0 7 0 0 7 7 7 3 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EJS42740.1 - 4.6e-13 49.2 1.1 0.054 13.6 0.0 7.2 7 0 0 7 7 6 2 RNA helicase AAA_19 PF13245.1 EJS42740.1 - 1.8e-11 43.6 5.3 0.46 10.2 0.0 6.7 7 0 0 7 7 6 3 Part of AAA domain Miro PF08477.8 EJS42740.1 - 2.2e-11 44.2 2.0 0.3 11.5 0.0 7.1 6 0 0 6 6 6 2 Miro-like protein ABC_tran PF00005.22 EJS42740.1 - 2e-10 41.1 33.7 0.00025 21.3 0.0 7.9 8 1 1 9 9 6 4 ABC transporter PduV-EutP PF10662.4 EJS42740.1 - 2.1e-10 40.2 3.8 0.017 14.5 0.0 5.9 6 0 0 6 6 6 3 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EJS42740.1 - 4.5e-10 39.3 10.3 0.061 13.0 0.1 7.6 7 0 0 7 7 7 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EJS42740.1 - 1.1e-09 37.6 8.0 0.064 12.4 0.3 5.7 6 0 0 6 6 6 4 Protein of unknown function, DUF258 AAA_25 PF13481.1 EJS42740.1 - 1.7e-09 37.3 5.0 0.0097 15.3 0.0 6.1 6 0 0 6 6 6 2 AAA domain Mg_chelatase PF01078.16 EJS42740.1 - 3.4e-09 36.1 4.0 1.6 7.8 0.0 8.3 9 1 1 10 10 9 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EJS42740.1 - 2.1e-08 34.3 8.2 2.5 8.0 0.1 6.9 7 0 0 7 7 6 2 AAA domain NACHT PF05729.7 EJS42740.1 - 2.7e-08 33.6 9.2 0.13 11.9 0.2 6.2 6 0 0 6 6 6 3 NACHT domain AAA_29 PF13555.1 EJS42740.1 - 2.9e-08 33.1 4.4 0.86 9.1 0.0 6.4 6 0 0 6 6 6 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EJS42740.1 - 5.5e-08 32.4 1.3 1.1 8.6 0.0 5.5 6 0 0 6 6 6 1 IstB-like ATP binding protein SRP54 PF00448.17 EJS42740.1 - 1.9e-07 30.7 5.6 0.15 11.4 0.4 5.6 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain RuvB_N PF05496.7 EJS42740.1 - 1e-06 27.9 1.2 0.12 11.3 0.0 4.9 5 0 0 5 5 5 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EJS42740.1 - 7e-06 25.4 0.2 2.9 7.0 0.0 5.0 5 0 0 5 5 5 1 PhoH-like protein ATP-synt_ab PF00006.20 EJS42740.1 - 8.1e-06 25.4 0.0 1.7 8.0 0.0 3.8 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EJS42740.1 - 0.0001 22.5 0.1 0.0076 16.5 0.0 11.4 11 2 2 13 13 7 6 AAA domain AAA_6 PF12774.2 EJS42740.1 - 0.0013 18.3 0.0 20 4.5 0.0 5.1 6 0 0 6 6 5 0 Hydrolytic ATP binding site of dynein motor region D1 NTPase_1 PF03266.10 EJS42740.1 - 0.038 13.6 10.5 2.9 7.5 0.4 5.8 7 0 0 7 7 6 0 NTPase FtsK_SpoIIIE PF01580.13 EJS42740.1 - 0.49 9.8 17.2 0.47 9.8 0.1 5.9 8 0 0 8 8 7 0 FtsK/SpoIIIE family Pkinase PF00069.20 EJS42741.1 - 2.6e-50 170.9 0.1 9.9e-50 169.0 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42741.1 - 2.2e-16 59.7 0.0 5.2e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase tRNA-synt_2 PF00152.15 EJS42742.1 - 1.7e-79 267.0 0.3 3.2e-79 266.1 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EJS42742.1 - 2.9e-07 30.2 0.1 6e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EJS42742.1 - 0.057 12.6 0.2 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) NARP1 PF12569.3 EJS42742.1 - 0.42 9.3 9.8 0.6 8.7 6.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Toprim_C_rpt PF13368.1 EJS42742.1 - 1.8 9.1 7.8 3.7 8.0 0.0 2.7 2 0 0 2 2 2 0 Topoisomerase C-terminal repeat Rab5ip PF07019.7 EJS42743.1 - 5.6e-16 58.4 5.2 6.5e-16 58.2 3.6 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Abhydro_lipase PF04083.11 EJS42744.1 - 6.2e-17 60.7 0.1 1.1e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EJS42744.1 - 0.00013 21.9 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family NIF PF03031.13 EJS42745.1 - 1.2e-49 167.9 0.3 1.2e-49 167.9 0.2 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DNA_gyraseA_C PF03989.8 EJS42745.1 - 0.029 13.6 0.0 0.36 10.1 0.0 2.3 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Spt5_N PF11942.3 EJS42745.1 - 0.071 13.7 22.0 1.5 9.4 9.5 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF4303 PF14136.1 EJS42745.1 - 0.24 11.0 5.6 0.6 9.7 3.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) SOBP PF15279.1 EJS42745.1 - 0.5 10.6 21.1 0.71 10.2 14.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Utp14 PF04615.8 EJS42745.1 - 8.7 4.3 40.9 13 3.8 28.3 1.1 1 0 0 1 1 1 0 Utp14 protein COX17 PF05051.8 EJS42746.1 - 7.2e-22 77.1 9.5 1e-21 76.6 6.6 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.8 EJS42746.1 - 0.00016 21.4 4.5 0.00027 20.7 3.1 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EJS42746.1 - 0.00017 21.2 4.0 0.00047 19.8 0.1 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like WBS_methylT PF12589.3 EJS42746.1 - 0.073 13.5 0.3 0.18 12.3 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome DEAD PF00270.24 EJS42747.1 - 4e-44 150.0 0.2 1.4e-43 148.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS42747.1 - 4.1e-25 87.4 0.0 1.3e-24 85.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sfi1 PF08457.5 EJS42749.1 - 1.8e-101 340.3 75.2 1.8e-101 340.3 52.1 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Sfi1_C PF10638.4 EJS42749.1 - 1.8e-40 137.6 2.1 6e-40 136.0 1.4 2.0 1 0 0 1 1 1 1 Spindle body associated protein C-terminus Dynamin_M PF01031.15 EJS42750.1 - 2.1e-112 374.7 0.0 3.4e-112 374.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EJS42750.1 - 1e-54 184.8 0.0 2.7e-54 183.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EJS42750.1 - 1.1e-28 98.8 1.5 3.2e-28 97.4 1.0 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EJS42750.1 - 0.0017 18.3 0.3 0.022 14.7 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EJS42750.1 - 0.027 14.9 0.0 0.077 13.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 EJS42750.1 - 0.032 13.9 0.1 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Utp12 PF04003.7 EJS42750.1 - 0.077 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family CBF PF03914.12 EJS42751.1 - 7.3e-38 129.6 0.8 2.1e-37 128.0 0.1 2.2 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 EJS42751.1 - 9.6e-35 118.7 0.6 9.6e-35 118.7 0.4 2.5 2 1 0 2 2 2 1 Nucleolar complex-associated protein 60KD_IMP PF02096.15 EJS42751.1 - 3.8 7.1 6.5 10 5.6 4.5 1.8 1 1 0 1 1 1 0 60Kd inner membrane protein Tom37_C PF11801.3 EJS42751.1 - 6.8 6.5 10.8 1.3 8.8 1.9 2.7 2 0 0 2 2 2 0 Tom37 C-terminal domain Response_reg PF00072.19 EJS42752.1 - 1.4e-19 70.1 0.0 2.3e-13 50.0 0.0 2.7 3 0 0 3 3 3 2 Response regulator receiver domain SMC_Nse1 PF07574.8 EJS42753.1 - 6.7e-47 159.7 0.1 8.6e-47 159.3 0.1 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EJS42753.1 - 4.5e-14 52.1 10.8 7.7e-14 51.4 7.5 1.4 1 0 0 1 1 1 1 RING-like domain DnaJ PF00226.26 EJS42754.1 - 1.6e-05 24.5 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EJS42754.1 - 0.00016 21.4 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Pam16 Ribosomal_L24e PF01246.15 EJS42755.1 - 1.6e-28 98.3 2.5 4.5e-28 96.9 1.7 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e TFIIF_alpha PF05793.7 EJS42755.1 - 0.16 10.3 17.9 0.22 9.8 12.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-FCS PF06467.9 EJS42755.1 - 0.3 10.7 5.9 0.64 9.7 4.1 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif AAA_23 PF13476.1 EJS42755.1 - 1.4 9.2 13.9 1.6 9.0 9.7 1.1 1 0 0 1 1 1 0 AAA domain Ten1 PF12658.2 EJS42756.1 - 6.1e-07 29.2 0.0 7.7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit GATA PF00320.22 EJS42758.1 - 3.9e-14 51.6 0.2 8.8e-14 50.5 0.1 1.6 1 0 0 1 1 1 1 GATA zinc finger GSu_C4xC__C2xCH PF09698.5 EJS42758.1 - 1 9.5 5.0 2.4 8.4 3.5 1.8 1 1 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) FHA PF00498.21 EJS42759.1 - 2.6e-12 46.6 0.0 4.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain PNP_UDP_1 PF01048.15 EJS42760.1 - 1.9e-33 115.3 0.0 2.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily NPCC PF08058.6 EJS42761.1 - 4.6e-35 120.5 3.0 7.4e-35 119.9 2.1 1.3 1 0 0 1 1 1 1 Nuclear pore complex component CytochromB561_N PF09786.4 EJS42761.1 - 6.2e-05 21.6 0.2 7e-05 21.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal NIF PF03031.13 EJS42762.1 - 7.8e-52 175.1 0.2 1.9e-51 173.9 0.2 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EJS42762.1 - 0.056 13.6 0.1 1.5 8.9 0.0 2.4 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Abhydro_lipase PF04083.11 EJS42763.1 - 2.3e-16 58.8 0.0 4.6e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EJS42763.1 - 5.2e-05 23.2 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EJS42763.1 - 0.00062 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold chaperone_DMP PF10448.4 EJS42764.1 - 9.4e-41 139.0 0.2 1.1e-40 138.8 0.1 1.0 1 0 0 1 1 1 1 20S proteasome chaperone SBDS_C PF09377.5 EJS42765.1 - 1.3e-35 121.7 2.8 1.3e-35 121.7 1.9 2.1 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 EJS42765.1 - 7.6e-33 112.1 2.4 1.2e-32 111.5 1.7 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein ALS2CR8 PF15299.1 EJS42765.1 - 0.18 11.4 2.4 1.4 8.4 0.1 2.1 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 HlyIII PF03006.15 EJS42766.1 - 2.9e-78 262.2 19.0 3.7e-78 261.9 13.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related zf-UBR PF02207.15 EJS42767.1 - 1.2e-13 50.4 8.0 1.2e-13 50.4 5.5 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Snf7 PF03357.16 EJS42768.1 - 1e-53 181.2 18.7 1e-53 181.2 13.0 2.0 2 0 0 2 2 2 1 Snf7 CHASE3 PF05227.8 EJS42768.1 - 0.041 13.5 8.0 0.13 11.8 5.0 2.2 1 1 1 2 2 2 0 CHASE3 domain DUF3966 PF13110.1 EJS42768.1 - 0.16 11.7 2.5 1.1 9.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3966) Snapin_Pallidin PF14712.1 EJS42768.1 - 3.4 8.0 17.2 0.05 13.9 4.7 3.0 3 1 0 4 4 4 0 Snapin/Pallidin Syntaxin PF00804.20 EJS42769.1 - 7.4e-20 71.0 3.2 7.4e-20 71.0 2.2 3.8 3 1 0 3 3 3 1 Syntaxin SNARE PF05739.14 EJS42769.1 - 1.4e-18 66.2 3.6 1.4e-18 66.2 2.5 2.5 3 0 0 3 3 3 1 SNARE domain Sed5p PF11416.3 EJS42769.1 - 1.5e-13 49.9 4.5 1.5e-13 49.9 3.1 2.4 2 0 0 2 2 2 1 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 EJS42769.1 - 0.00086 19.0 2.4 0.00086 19.0 1.6 2.4 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus MCPsignal PF00015.16 EJS42769.1 - 0.012 15.2 0.1 0.012 15.2 0.1 3.1 2 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 EJS42769.1 - 1.6 8.4 8.1 0.47 10.2 0.3 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Aminotran_1_2 PF00155.16 EJS42770.1 - 2.1e-80 270.4 0.0 2.4e-80 270.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AICARFT_IMPCHas PF01808.13 EJS42771.1 - 8.3e-127 422.6 0.0 1.1e-126 422.2 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EJS42771.1 - 5.7e-26 90.2 0.3 1.6e-25 88.8 0.0 1.8 2 0 0 2 2 2 1 MGS-like domain DKCLD PF08068.7 EJS42771.1 - 0.12 12.2 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 DKCLD (NUC011) domain Ribosomal_L15e PF00827.12 EJS42772.1 - 6.4e-91 303.0 14.9 7.4e-91 302.8 10.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 SNF2_N PF00176.18 EJS42773.1 - 7.6e-66 221.9 0.2 1.2e-65 221.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EJS42773.1 - 1.2e-13 50.9 0.0 3.4e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EJS42773.1 - 9.6e-11 41.3 0.0 2.4e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EJS42773.1 - 4.8e-09 35.9 5.1 9e-09 35.0 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EJS42773.1 - 2.4e-08 33.5 3.4 4.7e-08 32.5 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EJS42773.1 - 5.9e-08 32.5 6.8 1.2e-07 31.6 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EJS42773.1 - 1e-07 31.4 7.2 2e-07 30.5 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EJS42773.1 - 9.3e-07 28.4 6.9 1.9e-06 27.4 4.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 EJS42773.1 - 1.5e-05 24.5 0.0 3.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.1 EJS42773.1 - 0.0014 18.4 7.7 0.0033 17.2 5.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EJS42773.1 - 0.0023 17.6 3.0 0.0078 15.9 2.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EJS42773.1 - 0.0072 15.8 6.2 0.014 14.9 4.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EJS42773.1 - 0.012 15.7 1.5 0.027 14.5 1.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EJS42773.1 - 0.016 14.9 1.0 0.038 13.8 0.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EJS42773.1 - 0.14 12.1 3.9 0.42 10.6 2.7 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 EJS42773.1 - 0.51 9.8 3.0 1.4 8.4 2.0 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Bromodomain PF00439.20 EJS42774.1 - 1.1e-05 25.2 0.1 3.3e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Bromodomain Nramp PF01566.13 EJS42775.1 - 1.4e-96 323.4 13.9 1.8e-96 323.1 9.6 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein HATPase_c_3 PF13589.1 EJS42776.1 - 4.5e-11 42.5 0.2 1.5e-10 40.8 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EJS42776.1 - 2.4e-10 39.8 0.2 5e-10 38.8 0.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EJS42776.1 - 8.9e-09 35.0 0.1 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase COX6B PF02297.12 EJS42777.1 - 2.8e-20 72.0 5.4 3.2e-20 71.8 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Somatostatin PF03002.10 EJS42777.1 - 0.078 12.6 0.2 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Somatostatin/Cortistatin family APOBEC_C PF05240.9 EJS42777.1 - 0.13 11.7 3.1 0.33 10.3 2.2 1.7 1 1 0 1 1 1 0 APOBEC-like C-terminal domain UCR_hinge PF02320.11 EJS42777.1 - 0.18 11.7 1.8 0.27 11.2 0.9 1.6 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EJS42777.1 - 0.32 10.8 6.2 0.75 9.6 1.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Thioredoxin PF00085.15 EJS42778.1 - 1.6e-32 111.2 0.2 1.8e-32 111.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EJS42778.1 - 2.8e-09 37.1 0.3 1.1e-07 32.0 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EJS42778.1 - 1.2e-08 34.9 0.0 1.9e-06 27.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EJS42778.1 - 1.1e-07 31.4 0.1 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EJS42778.1 - 4.4e-06 26.3 0.1 5.4e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EJS42778.1 - 1.2e-05 24.8 0.1 4.8e-05 22.9 0.0 1.7 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 EJS42778.1 - 0.00069 19.5 0.1 0.0012 18.8 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.11 EJS42778.1 - 0.0025 17.3 0.0 0.0028 17.1 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 TraF PF13728.1 EJS42778.1 - 0.018 14.5 0.1 0.042 13.3 0.1 1.6 1 1 0 1 1 1 0 F plasmid transfer operon protein TPP_enzyme_M PF00205.17 EJS42779.1 - 2.8e-36 124.3 0.0 1.4e-35 122.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 EJS42779.1 - 3.3e-34 117.8 0.1 5.6e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EJS42779.1 - 2.1e-14 53.3 0.0 4.7e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.1 EJS42779.1 - 0.052 13.4 0.2 3.3 7.6 0.1 2.7 2 0 0 2 2 2 0 OCC1 family Cnd3 PF12719.2 EJS42780.1 - 1.8e-05 23.8 0.4 0.002 17.1 0.1 2.6 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 EJS42780.1 - 0.0049 16.8 0.1 8.7 6.7 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat NeuB PF03102.9 EJS42780.1 - 0.11 11.6 2.8 0.86 8.6 1.4 2.2 2 0 0 2 2 2 0 NeuB family IncA PF04156.9 EJS42780.1 - 7.2 6.1 15.4 0.64 9.5 6.8 2.1 2 0 0 2 2 2 0 IncA protein DUF2781 PF10914.3 EJS42781.1 - 1.8e-37 128.4 7.7 2e-37 128.2 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Phi-29_GP3 PF05435.6 EJS42782.1 - 0.017 14.3 0.4 0.025 13.7 0.3 1.3 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 WD40 PF00400.27 EJS42783.1 - 2.5e-11 42.9 3.5 0.038 13.8 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat FA_hydroxylase PF04116.8 EJS42784.1 - 2.5e-11 43.9 19.1 2.5e-11 43.9 13.2 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_hydro_47 PF01532.15 EJS42785.1 - 1.6e-74 251.2 0.0 3.3e-74 250.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 SHMT PF00464.14 EJS42786.1 - 1.3e-211 702.1 0.0 1.5e-211 701.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EJS42786.1 - 5e-08 32.2 0.0 9e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EJS42786.1 - 6.3e-07 28.4 0.0 8.6e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EJS42786.1 - 0.00032 19.9 0.0 0.00087 18.5 0.0 1.7 1 1 1 2 2 2 1 Beta-eliminating lyase RNase_T PF00929.19 EJS42787.1 - 1.1e-36 126.5 0.1 1.5e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Exonuclease B3_4 PF03483.12 EJS42788.1 - 5.1e-27 94.4 0.1 9.3e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EJS42788.1 - 3.5e-17 62.0 0.1 4.6e-15 55.1 0.0 2.7 2 0 0 2 2 2 1 tRNA synthetase B5 domain SLS PF14611.1 EJS42788.1 - 0.0049 16.3 0.6 0.29 10.5 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Herpes_V23 PF01802.12 EJS42788.1 - 0.037 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein DUF3533 PF12051.3 EJS42788.1 - 0.16 10.6 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) UPF0121 PF03661.8 EJS42789.1 - 0.0014 17.9 21.5 0.004 16.3 14.9 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF788 PF05620.6 EJS42790.1 - 3e-48 163.8 2.0 3.4e-48 163.7 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) TB2_DP1_HVA22 PF03134.14 EJS42790.1 - 0.075 12.7 1.6 0.14 11.9 0.4 2.0 1 1 1 2 2 2 0 TB2/DP1, HVA22 family SPC22 PF04573.7 EJS42791.1 - 4.1e-63 211.7 8.2 4.5e-63 211.6 5.7 1.0 1 0 0 1 1 1 1 Signal peptidase subunit PPR PF01535.15 EJS42792.1 - 1e-10 40.8 3.0 0.63 10.1 0.0 9.7 11 0 0 11 11 11 2 PPR repeat PPR_2 PF13041.1 EJS42792.1 - 1.3e-10 41.0 13.8 0.016 15.1 0.0 9.7 9 2 2 11 11 11 3 PPR repeat family PPR_3 PF13812.1 EJS42792.1 - 3.3e-10 39.4 8.7 9.1 6.8 0.0 10.8 14 0 0 14 14 14 3 Pentatricopeptide repeat domain TPR_14 PF13428.1 EJS42792.1 - 0.0018 18.7 0.0 32 5.5 0.0 5.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EJS42792.1 - 0.0029 17.8 0.0 4.3 7.7 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EJS42792.1 - 0.0053 16.4 0.2 1.3 8.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EJS42792.1 - 0.051 14.0 0.1 1.3e+02 3.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribonuc_red_lgN PF00317.16 EJS42792.1 - 0.068 12.9 4.4 5.6 6.8 0.0 4.6 5 0 0 5 5 5 0 Ribonucleotide reductase, all-alpha domain GRAM PF02893.15 EJS42793.1 - 3.9e-19 67.9 0.3 8.1e-19 66.9 0.2 1.6 1 0 0 1 1 1 1 GRAM domain Syntaphilin PF15290.1 EJS42793.1 - 1.2 8.5 9.8 0.041 13.3 2.5 1.7 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp USP8_dimer PF08969.6 EJS42794.1 - 4.7e-05 23.3 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain Ribosomal_L16 PF00252.13 EJS42795.1 - 1.2e-33 115.6 0.1 2e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rax2 PF12768.2 EJS42798.1 - 4.1e-65 219.8 2.4 4.1e-65 219.8 1.6 6.3 4 1 0 6 6 6 4 Cortical protein marker for cell polarity Actin PF00022.14 EJS42799.1 - 5.2e-54 183.1 0.0 6.5e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Actin HSP70 PF00012.15 EJS42800.1 - 3.7e-274 910.2 8.5 4.2e-274 910.0 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EJS42800.1 - 1.3e-17 63.4 0.0 1.3e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EJS42800.1 - 0.0015 18.1 0.0 0.0046 16.6 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EJS42800.1 - 0.0019 17.1 0.5 0.042 12.6 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 EJS42800.1 - 0.034 13.4 0.0 3.9 6.6 0.0 2.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 EJS42800.1 - 0.058 12.4 1.0 0.37 9.8 0.0 2.5 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase Surf_Ag_VNR PF07244.10 EJS42800.1 - 0.3 11.5 2.8 31 5.0 0.5 3.4 3 0 0 3 3 3 0 Surface antigen variable number repeat ENTH PF01417.15 EJS42801.1 - 6e-36 123.0 1.9 9.1e-36 122.4 1.3 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EJS42801.1 - 2.5e-05 23.1 0.2 3.5e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EJS42801.1 - 0.0065 16.1 0.7 0.011 15.3 0.5 1.4 1 0 0 1 1 1 1 VHS domain Prp19 PF08606.6 EJS42802.1 - 8.5e-27 92.6 0.1 1.8e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 EJS42802.1 - 0.00042 20.2 0.0 0.00085 19.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain Clp1 PF06807.9 EJS42803.1 - 7.3e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EJS42803.1 - 0.0014 18.3 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EJS42803.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EJS42803.1 - 0.0075 16.1 0.0 0.049 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EJS42803.1 - 0.013 15.0 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EJS42803.1 - 0.015 15.8 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein G-alpha PF00503.15 EJS42803.1 - 0.067 11.8 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit VirE PF05272.6 EJS42803.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 2 0 0 2 2 2 0 Virulence-associated protein E Dynamin_N PF00350.18 EJS42803.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Dynamin family Arf PF00025.16 EJS42803.1 - 0.15 11.3 0.1 0.31 10.2 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.24 EJS42804.1 - 2.5e-94 312.4 0.0 1.8e-47 160.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EJS42804.1 - 2.5e-15 56.1 0.0 3e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EJS42804.1 - 5.6e-12 46.0 2.6 0.00034 20.6 0.0 4.3 3 2 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EJS42804.1 - 8.2e-12 46.0 0.1 1.3e-06 29.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 EJS42804.1 - 2.3e-11 43.9 0.0 0.00021 21.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EJS42804.1 - 3.2e-11 43.4 0.4 0.0032 17.6 0.0 5.0 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.1 EJS42804.1 - 2.4e-10 40.4 0.0 0.00023 21.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EJS42804.1 - 5.6e-10 38.6 0.0 0.0011 18.1 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_14 PF13173.1 EJS42804.1 - 5.7e-10 39.1 0.0 0.0015 18.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EJS42804.1 - 1.4e-09 37.8 0.2 0.003 17.2 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EJS42804.1 - 2.4e-09 37.5 0.5 0.0001 22.6 0.0 3.7 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.8 EJS42804.1 - 1.5e-08 33.8 0.0 0.00028 19.7 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 EJS42804.1 - 1.8e-07 31.3 0.0 0.012 15.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 EJS42804.1 - 1.9e-07 31.4 0.3 0.015 15.5 0.0 3.5 4 0 0 4 4 2 2 ABC transporter Vps4_C PF09336.5 EJS42804.1 - 3.5e-07 30.0 0.1 0.00012 21.8 0.0 3.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.1 EJS42804.1 - 5.6e-07 29.1 3.2 0.65 9.3 0.1 4.7 2 2 1 5 5 5 2 AAA domain IstB_IS21 PF01695.12 EJS42804.1 - 1.3e-06 27.9 0.3 0.04 13.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EJS42804.1 - 1.9e-06 27.4 1.6 0.061 13.0 0.1 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 EJS42804.1 - 2e-06 27.8 0.0 0.041 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EJS42804.1 - 2.7e-06 26.6 0.4 0.027 13.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI SKI PF01202.17 EJS42804.1 - 8.2e-06 25.7 0.0 0.073 12.9 0.0 3.0 2 0 0 2 2 2 2 Shikimate kinase Cytidylate_kin2 PF13189.1 EJS42804.1 - 8.9e-06 25.7 0.0 0.0012 18.7 0.0 3.0 3 0 0 3 3 2 1 Cytidylate kinase-like family AAA_3 PF07726.6 EJS42804.1 - 1.4e-05 24.7 0.0 0.073 12.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EJS42804.1 - 2e-05 24.3 0.1 0.43 10.2 0.0 3.4 3 0 0 3 3 3 2 NACHT domain Viral_helicase1 PF01443.13 EJS42804.1 - 0.00014 21.4 0.0 0.51 9.8 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EJS42804.1 - 0.00016 20.5 0.0 0.071 11.7 0.0 2.6 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 EJS42804.1 - 0.00021 20.2 0.3 0.31 9.8 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain Sigma54_activ_2 PF14532.1 EJS42804.1 - 0.00024 21.1 0.0 0.64 10.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EJS42804.1 - 0.00028 20.6 0.0 3.3 7.3 0.0 3.8 2 2 1 3 3 3 0 Archaeal ATPase AAA_11 PF13086.1 EJS42804.1 - 0.00028 20.5 0.3 0.66 9.4 0.0 3.6 3 1 0 3 3 3 1 AAA domain DUF815 PF05673.8 EJS42804.1 - 0.00057 18.8 0.0 0.23 10.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) CPT PF07931.7 EJS42804.1 - 0.00077 19.1 0.0 0.018 14.6 0.0 2.5 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.21 EJS42804.1 - 0.0011 18.4 0.0 0.74 9.2 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain SRPRB PF09439.5 EJS42804.1 - 0.0016 17.6 0.0 0.95 8.6 0.0 3.4 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Parvo_NS1 PF01057.12 EJS42804.1 - 0.0017 17.2 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 KaiC PF06745.8 EJS42804.1 - 0.0023 17.0 0.1 2.8 7.0 0.0 3.3 2 1 0 3 3 3 1 KaiC AAA_24 PF13479.1 EJS42804.1 - 0.0028 17.2 0.1 3.1 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EJS42804.1 - 0.0032 16.9 0.0 0.97 8.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 EJS42804.1 - 0.0064 15.7 0.7 1.8 7.7 0.0 2.9 3 0 0 3 3 2 1 PhoH-like protein NTPase_1 PF03266.10 EJS42804.1 - 0.013 15.2 0.0 4.1 7.0 0.0 2.7 2 0 0 2 2 2 0 NTPase UPF0079 PF02367.12 EJS42804.1 - 0.016 14.8 0.0 5 6.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EJS42804.1 - 0.02 14.4 0.0 6.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EJS42804.1 - 0.021 15.2 1.0 15 6.1 0.0 4.2 4 1 0 4 4 3 0 Miro-like protein MMR_HSR1 PF01926.18 EJS42804.1 - 0.024 14.6 0.1 2.4 8.1 0.0 3.5 3 1 0 3 3 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 EJS42804.1 - 0.038 13.1 0.9 0.9 8.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF258 ADK PF00406.17 EJS42804.1 - 0.041 13.7 1.2 21 4.9 0.0 3.4 3 0 0 3 3 3 0 Adenylate kinase KTI12 PF08433.5 EJS42804.1 - 0.043 13.0 2.0 4.7 6.3 0.0 3.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 T2SE PF00437.15 EJS42804.1 - 0.067 12.0 0.0 3.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 EJS42804.1 - 0.1 12.1 0.0 6.3 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain KH_1 PF00013.24 EJS42806.1 - 7.3e-08 31.9 1.2 0.00014 21.3 0.1 4.2 4 0 0 4 4 4 2 KH domain KH_3 PF13014.1 EJS42806.1 - 0.013 15.1 5.8 0.016 14.8 0.1 3.6 4 0 0 4 4 4 0 KH domain Phosphodiest PF01663.17 EJS42807.1 - 1e-12 48.1 0.9 1.6e-12 47.4 0.6 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EJS42807.1 - 0.0017 17.7 5.6 0.0056 16.0 2.5 2.3 2 0 0 2 2 2 1 Metalloenzyme superfamily YrhC PF14143.1 EJS42807.1 - 0.63 10.0 5.5 0.28 11.1 0.8 2.8 2 0 0 2 2 2 0 YrhC-like protein Peptidase_M24 PF00557.19 EJS42808.1 - 6e-38 130.5 0.0 3.4e-37 128.0 0.0 2.0 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EJS42808.1 - 2.2e-11 44.3 0.0 1.4e-10 41.7 0.0 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Fe-S_biosyn PF01521.15 EJS42809.1 - 6e-19 68.0 0.0 1.3e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.2 EJS42809.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) DUF4272 PF14094.1 EJS42809.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) AAA_2 PF07724.9 EJS42810.1 - 1.3e-46 158.6 0.0 3.1e-45 154.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EJS42810.1 - 1.4e-24 86.7 0.2 1.2e-14 54.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EJS42810.1 - 3.2e-23 81.4 1.4 1.3e-22 79.5 1.0 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 EJS42810.1 - 1.9e-15 56.4 5.6 1.7e-10 40.6 0.7 3.4 3 0 0 3 3 3 2 Clp amino terminal domain AAA_5 PF07728.9 EJS42810.1 - 4e-15 55.7 0.0 1.4e-07 31.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EJS42810.1 - 2.2e-11 43.5 0.1 3.6e-08 33.0 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 EJS42810.1 - 4.8e-11 42.9 5.2 0.00028 20.9 0.0 4.7 4 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 EJS42810.1 - 2.6e-08 34.0 0.2 0.0088 16.1 0.0 3.7 3 1 0 3 3 2 2 AAA domain TIP49 PF06068.8 EJS42810.1 - 1.2e-05 24.2 2.4 0.12 11.1 0.0 4.1 4 0 0 4 4 4 2 TIP49 C-terminus Mg_chelatase PF01078.16 EJS42810.1 - 0.00084 18.5 0.0 1.7 7.7 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EJS42810.1 - 0.001 18.2 0.3 0.13 11.3 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin Arch_ATPase PF01637.13 EJS42810.1 - 0.0014 18.3 5.0 1.2 8.8 0.0 4.4 3 1 1 4 4 4 2 Archaeal ATPase AAA_19 PF13245.1 EJS42810.1 - 0.0014 18.3 0.0 0.72 9.6 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EJS42810.1 - 0.0016 18.3 0.1 0.16 11.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.6 EJS42810.1 - 0.0028 17.2 0.0 0.53 9.8 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EJS42810.1 - 0.0036 18.1 7.5 0.27 12.0 0.0 4.2 4 1 0 4 4 3 1 AAA domain NACHT PF05729.7 EJS42810.1 - 0.0037 16.9 0.0 1.4 8.5 0.0 2.9 2 0 0 2 2 2 1 NACHT domain Torsin PF06309.6 EJS42810.1 - 0.0039 17.0 0.0 0.014 15.2 0.0 1.9 2 0 0 2 2 1 1 Torsin IstB_IS21 PF01695.12 EJS42810.1 - 0.013 14.9 0.0 0.85 9.0 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EJS42810.1 - 0.034 13.8 0.1 3.8 7.2 0.0 3.4 3 0 0 3 3 3 0 NTPase PEPCK_ATP PF01293.15 EJS42810.1 - 0.055 11.9 0.0 0.12 10.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EJS42810.1 - 0.79 10.0 6.7 6.3 7.1 0.0 4.0 4 0 0 4 4 3 0 AAA domain DUF4337 PF14235.1 EJS42810.1 - 3 7.6 8.0 11 5.8 5.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MIP PF00230.15 EJS42811.1 - 4.9e-84 281.3 9.7 7e-84 280.8 6.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein Fer2_3 PF13085.1 EJS42812.1 - 9.8e-34 115.4 0.1 2e-33 114.5 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EJS42812.1 - 2.9e-10 40.3 8.0 2.9e-10 40.3 5.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EJS42812.1 - 5.9e-09 35.8 6.3 5.9e-09 35.8 4.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EJS42812.1 - 3.6e-06 27.3 3.0 3.6e-06 27.3 2.1 2.7 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EJS42812.1 - 0.00011 21.8 5.3 0.00011 21.8 3.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EJS42812.1 - 0.0015 18.8 6.6 0.0015 18.8 4.6 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EJS42812.1 - 0.0023 18.1 9.9 0.027 14.7 0.1 3.1 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 EJS42812.1 - 0.0035 17.0 1.1 0.0035 17.0 0.8 2.5 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EJS42812.1 - 2 9.0 8.6 0.42 11.2 0.2 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_2 PF12797.2 EJS42812.1 - 8.8 6.4 18.6 0.3 11.0 3.3 3.5 3 0 0 3 3 3 0 4Fe-4S binding domain DUF1162 PF06650.7 EJS42813.1 - 2.1e-82 276.4 7.8 5.3e-80 268.5 1.4 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EJS42813.1 - 3.2e-40 136.3 1.6 5.6e-40 135.5 0.1 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter MIP PF00230.15 EJS42814.1 - 1.6e-23 83.3 6.6 1.8e-23 83.1 4.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein ABC2_membrane_3 PF12698.2 EJS42814.1 - 1.4 7.8 9.7 1.7 7.5 6.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein FAD_binding_8 PF08022.7 EJS42815.1 - 8.5e-28 96.3 0.1 2.5e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EJS42815.1 - 1.3e-22 80.4 0.0 3e-22 79.1 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EJS42815.1 - 1.4e-18 67.1 12.6 1.4e-18 67.1 8.7 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EJS42815.1 - 0.00093 19.7 0.0 0.23 12.0 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF3262 PF11660.3 EJS42815.1 - 0.7 10.0 7.5 1 9.4 2.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3262) IBP39 PF11422.3 EJS42816.1 - 0.066 12.7 0.6 0.084 12.3 0.4 1.2 1 0 0 1 1 1 0 Initiator binding protein 39 kDa ABC_membrane PF00664.18 EJS42817.1 - 2.9e-56 190.9 31.1 3.3e-32 111.9 7.3 3.6 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EJS42817.1 - 7e-56 188.3 0.5 3.6e-33 114.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.1 EJS42817.1 - 1.7e-11 44.8 6.7 2.3e-06 28.0 0.0 3.7 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 EJS42817.1 - 2.6e-09 36.6 6.1 0.0002 20.6 1.4 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EJS42817.1 - 6.4e-08 32.0 0.4 0.0022 17.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EJS42817.1 - 1.9e-07 31.3 3.8 1.5e-06 28.3 0.2 6.2 6 1 0 6 6 5 2 AAA domain T2SE PF00437.15 EJS42817.1 - 1e-06 27.8 0.0 0.0058 15.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EJS42817.1 - 1.8e-06 27.8 0.0 0.016 15.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EJS42817.1 - 2.6e-06 26.7 0.0 0.046 12.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EJS42817.1 - 1.3e-05 26.0 0.0 0.11 13.2 0.0 3.3 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EJS42817.1 - 1.4e-05 25.5 0.1 0.39 11.2 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EJS42817.1 - 5.2e-05 23.4 0.1 0.57 10.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EJS42817.1 - 7.1e-05 22.8 0.1 0.52 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EJS42817.1 - 7.9e-05 22.1 0.0 0.038 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EJS42817.1 - 8.9e-05 22.3 0.3 0.051 13.3 0.1 2.7 2 0 0 2 2 2 1 Dynamin family ATP_bind_1 PF03029.12 EJS42817.1 - 0.00025 20.6 0.0 3.2 7.2 0.0 3.5 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein ResIII PF04851.10 EJS42817.1 - 0.00027 20.8 0.7 2.6 7.8 0.0 3.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EJS42817.1 - 0.00039 19.9 0.1 0.035 13.5 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain Zeta_toxin PF06414.7 EJS42817.1 - 0.0005 19.2 0.0 0.85 8.6 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin MobB PF03205.9 EJS42817.1 - 0.00056 19.6 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EJS42817.1 - 0.00081 19.7 0.0 0.9 9.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EJS42817.1 - 0.0031 17.0 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA PF00004.24 EJS42817.1 - 0.0032 17.6 0.9 3.3 7.9 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EJS42817.1 - 0.0051 16.6 7.4 0.43 10.3 0.7 3.0 2 1 0 2 2 2 2 Domain of unknown function DUF87 AAA_33 PF13671.1 EJS42817.1 - 0.0096 15.8 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EJS42817.1 - 0.011 15.4 0.2 0.28 10.9 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain TrwB_AAD_bind PF10412.4 EJS42817.1 - 0.015 13.9 0.0 4 5.9 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 EJS42817.1 - 0.016 14.8 0.1 7.7 6.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EJS42817.1 - 0.038 13.3 0.1 5 6.5 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein ArgK PF03308.11 EJS42817.1 - 0.048 12.4 0.1 0.16 10.7 0.0 1.8 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 EJS42817.1 - 0.049 13.0 4.0 2.1 7.7 0.3 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EJS42817.1 - 0.078 12.5 0.7 9.2 5.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EJS42817.1 - 0.13 11.4 0.9 1.3 8.2 0.0 2.6 3 0 0 3 3 3 0 PhoH-like protein CENP-F_C_Rb_bdg PF10490.4 EJS42817.1 - 0.21 10.9 0.2 0.47 9.8 0.2 1.4 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 AAA_28 PF13521.1 EJS42817.1 - 0.4 10.6 0.6 11 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 EJS42818.1 - 6.3e-19 67.3 4.7 4.8e-16 58.1 0.2 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS42818.1 - 6.3e-14 51.7 2.5 1.4e-07 31.3 0.1 2.4 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS42818.1 - 1.9e-07 30.7 2.2 3.3e-05 23.6 0.2 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TauD PF02668.11 EJS42819.1 - 2.7e-47 161.5 0.9 3.5e-47 161.2 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Epimerase PF01370.16 EJS42820.1 - 3.3e-16 59.4 0.0 7.7e-16 58.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EJS42820.1 - 1.1e-12 48.3 0.0 1.4e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EJS42820.1 - 1.9e-11 43.2 0.1 4.4e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EJS42820.1 - 2.1e-05 23.6 0.0 0.00057 18.8 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EJS42820.1 - 2.2e-05 23.5 0.1 0.0001 21.3 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EJS42820.1 - 0.00016 21.6 0.1 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EJS42820.1 - 0.00042 19.6 0.0 0.00071 18.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.12 EJS42820.1 - 0.0026 18.1 0.0 0.0063 16.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EJS42820.1 - 0.0048 16.8 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 EJS42820.1 - 0.018 13.9 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 EJS42820.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 EJS42820.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.11 EJS42821.1 - 5.5e-18 64.8 37.0 5.5e-18 64.8 25.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3353 PF11833.3 EJS42821.1 - 0.0014 18.1 4.3 0.0014 18.1 3.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3353) Myb_DNA-bind_6 PF13921.1 EJS42822.1 - 6.8e-27 93.3 3.9 5e-10 39.3 0.0 3.7 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EJS42822.1 - 2.4e-24 85.1 8.4 1.8e-12 47.0 0.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EJS42822.1 - 0.0039 17.0 2.6 0.52 10.2 0.2 2.6 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_5 PF13873.1 EJS42822.1 - 0.044 13.6 4.3 0.18 11.7 0.3 3.3 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain SKG6 PF08693.5 EJS42823.1 - 2.6e-05 23.4 2.5 6.3e-05 22.1 1.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 EJS42823.1 - 0.0095 15.6 3.8 0.0095 15.6 2.6 2.7 2 1 0 3 3 3 1 Transmembrane protein 51 Vpu PF00558.14 EJS42823.1 - 0.11 12.0 0.0 0.31 10.6 0.0 1.8 1 0 0 1 1 1 0 Vpu protein Ribosomal_L1 PF00687.16 EJS42824.1 - 1e-44 152.5 1.3 1.3e-44 152.2 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Glyco_transf_15 PF01793.11 EJS42825.1 - 4.3e-128 426.9 18.5 5.3e-128 426.6 12.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TFIIE_beta PF02186.10 EJS42826.1 - 5e-23 80.8 0.5 1.2e-22 79.6 0.3 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF1987 PF09345.5 EJS42826.1 - 0.063 13.0 0.1 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Las1 PF04031.8 EJS42827.1 - 9.9e-53 177.9 0.1 2.6e-52 176.5 0.1 1.8 1 0 0 1 1 1 1 Las1-like PHTB1_C PF14728.1 EJS42827.1 - 0.056 12.2 2.0 0.087 11.6 1.4 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus Secretin_N_2 PF07655.8 EJS42827.1 - 0.074 13.4 0.6 0.074 13.4 0.4 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Zn_clus PF00172.13 EJS42828.1 - 1.7e-08 34.1 7.5 4.4e-08 32.8 5.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pam17 PF08566.5 EJS42829.1 - 7e-72 240.7 0.1 8.5e-72 240.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF1086 PF06461.6 EJS42829.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) Topo_Zn_Ribbon PF08272.6 EJS42829.1 - 0.18 11.2 0.7 3.9 6.8 0.1 2.3 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like peroxidase PF00141.18 EJS42830.1 - 1.2e-42 146.0 0.0 2e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase TAT_signal PF10518.4 EJS42830.1 - 9.4 6.5 8.5 2.2 8.4 0.3 2.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Acyltransferase PF01553.16 EJS42831.1 - 5.3e-07 29.1 0.0 5e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase TRAPP PF04051.11 EJS42832.1 - 3.8e-36 123.9 0.0 4.7e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Hydrolase_like PF13242.1 EJS42833.1 - 5.2e-25 86.9 0.0 1.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EJS42833.1 - 1.4e-24 85.9 0.0 2.4e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EJS42833.1 - 0.00017 21.8 0.2 0.5 10.5 0.0 3.2 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EJS42833.1 - 0.00079 19.8 0.0 0.013 15.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CIAPIN1 PF05093.8 EJS42834.1 - 2.3e-36 123.8 5.6 6.2e-36 122.4 3.9 1.7 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF2340 PF10209.4 EJS42835.1 - 9.7e-58 193.6 3.0 1.2e-57 193.2 2.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Peptidase_C13 PF01650.13 EJS42835.1 - 0.0046 16.2 1.4 0.028 13.7 0.4 1.9 1 1 1 2 2 2 1 Peptidase C13 family GST_N_2 PF13409.1 EJS42837.1 - 7.5e-23 80.3 0.0 1.8e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EJS42837.1 - 7.6e-11 41.7 0.0 2.4e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EJS42837.1 - 0.0021 18.2 0.1 0.28 11.4 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain DBR1 PF05011.8 EJS42838.1 - 5.1 6.9 6.4 0.89 9.4 0.8 2.3 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain Lactamase_B_2 PF12706.2 EJS42839.1 - 2.7e-39 134.7 0.3 5.1e-39 133.8 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EJS42839.1 - 6.5e-24 83.1 0.0 1.5e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease DUF3535 PF12054.3 EJS42839.1 - 0.021 13.4 0.0 0.036 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) THF_DHG_CYH_C PF02882.14 EJS42840.1 - 6.4e-18 64.3 0.0 7.1e-11 41.4 0.0 2.6 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EJS42840.1 - 5.6e-17 61.8 0.1 2.7e-16 59.6 0.0 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain RTP PF02334.11 EJS42840.1 - 0.05 13.5 0.2 0.24 11.3 0.0 2.0 1 1 1 2 2 2 0 Replication terminator protein Brix PF04427.13 EJS42841.1 - 6.1e-39 133.6 1.7 8e-39 133.2 1.2 1.2 1 0 0 1 1 1 1 Brix domain Nucleoporin_C PF03177.9 EJS42842.1 - 2.7e-61 207.8 19.8 4e-61 207.2 13.7 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EJS42842.1 - 9.6e-58 195.9 7.1 1.5e-57 195.2 4.9 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DASH_Dad2 PF08654.5 EJS42843.1 - 2.9e-28 97.8 3.5 2.6e-27 94.8 2.4 1.9 1 1 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.5 EJS42843.1 - 4.1e-05 23.0 1.5 8.1e-05 22.1 1.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DHC_N2 PF08393.8 EJS42843.1 - 0.013 14.0 0.6 0.015 13.8 0.4 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 DUF3585 PF12130.3 EJS42843.1 - 0.027 14.3 0.6 0.043 13.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) Baculo_PEP_C PF04513.7 EJS42843.1 - 0.054 13.3 1.6 0.065 13.0 1.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ran-binding PF05508.6 EJS42843.1 - 0.068 12.0 0.6 0.092 11.6 0.4 1.1 1 0 0 1 1 1 0 RanGTP-binding protein Vps51 PF08700.6 EJS42843.1 - 0.075 12.8 0.6 0.22 11.3 0.4 1.8 1 1 0 1 1 1 0 Vps51/Vps67 TAF1_subA PF14929.1 EJS42843.1 - 0.11 10.8 0.1 0.12 10.7 0.1 1.0 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A DUF3610 PF12272.3 EJS42843.1 - 0.12 11.9 0.2 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) Phage_GP20 PF06810.6 EJS42843.1 - 0.3 10.5 6.1 0.035 13.5 0.8 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 GTP_EFTU PF00009.22 EJS42844.1 - 2.1e-43 147.9 0.0 3.5e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EJS42844.1 - 4.4e-13 49.1 2.5 9.6e-13 48.0 1.7 1.6 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 EJS42844.1 - 1.6e-07 31.2 0.0 7e-06 25.9 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 EJS42844.1 - 0.00031 20.8 0.0 0.0065 16.6 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu C-terminal domain Miro PF08477.8 EJS42844.1 - 0.0015 19.0 0.0 0.023 15.2 0.0 2.5 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EJS42844.1 - 0.002 17.9 0.1 0.77 9.5 0.0 2.7 1 1 1 2 2 2 2 Dynamin family Ras PF00071.17 EJS42844.1 - 0.0023 17.3 0.2 0.037 13.4 0.0 2.5 2 0 0 2 2 2 1 Ras family GTP_EFTU_D2 PF03144.20 EJS42844.1 - 0.0056 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EJS42844.1 - 0.016 14.4 0.1 1.3 8.2 0.0 2.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EJS42844.1 - 0.029 13.6 0.2 0.5 9.6 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 EJS42844.1 - 0.037 13.2 0.1 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dabb PF07876.7 EJS42844.1 - 0.041 14.3 0.3 25 5.4 0.0 3.4 3 0 0 3 3 3 0 Stress responsive A/B Barrel Domain Septin PF00735.13 EJS42844.1 - 0.051 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Septin MRP-L20 PF12824.2 EJS42845.1 - 1.5e-44 151.8 2.5 1.9e-44 151.5 1.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Frankia_peptide PF14407.1 EJS42845.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. HTH_38 PF13936.1 EJS42845.1 - 0.055 13.0 0.1 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain gag-asp_proteas PF13975.1 EJS42845.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SNARE_assoc PF09335.6 EJS42846.1 - 2.3e-15 56.8 6.0 2.3e-15 56.8 4.1 2.9 2 1 1 3 3 3 1 SNARE associated Golgi protein Tetraspannin PF00335.15 EJS42846.1 - 0.091 12.0 4.7 1.7 7.8 3.2 2.4 2 0 0 2 2 2 0 Tetraspanin family TipAS PF07739.8 EJS42846.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain E1-E2_ATPase PF00122.15 EJS42846.1 - 0.52 9.2 4.1 0.36 9.8 1.0 1.9 2 0 0 2 2 2 0 E1-E2 ATPase DUF4231 PF14015.1 EJS42846.1 - 2.9 7.9 13.6 7.2 6.6 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) LIM PF00412.17 EJS42847.1 - 2.6e-12 46.6 25.3 6.6e-07 29.3 8.5 2.4 2 0 0 2 2 2 2 LIM domain PTR2 PF00854.16 EJS42849.1 - 9.9e-79 264.8 20.8 9.9e-79 264.8 14.4 1.3 2 0 0 2 2 2 1 POT family MFS_1 PF07690.11 EJS42849.1 - 5.7e-06 25.2 32.1 5.7e-06 25.2 22.3 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Menin PF05053.8 EJS42850.1 - 0.61 8.1 8.9 1.3 7.0 6.1 1.5 1 0 0 1 1 1 0 Menin Ctr PF04145.10 EJS42850.1 - 4.9 7.1 6.1 16 5.5 0.0 3.2 3 0 0 3 3 3 0 Ctr copper transporter family PHD PF00628.24 EJS42851.1 - 8.9e-11 41.3 8.8 1.8e-10 40.3 6.1 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EJS42851.1 - 2.8e-07 31.0 3.6 7.5e-07 29.5 0.0 3.2 3 1 0 3 3 3 1 SET domain PHD_2 PF13831.1 EJS42851.1 - 0.00023 20.4 3.2 0.00048 19.3 2.2 1.5 1 0 0 1 1 1 1 PHD-finger UNC-50 PF05216.8 EJS42852.1 - 1.8e-90 302.1 21.2 2.1e-90 302.0 14.7 1.0 1 0 0 1 1 1 1 UNC-50 family UPF0542 PF15086.1 EJS42852.1 - 4.9 6.9 5.6 3.6 7.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 Snf7 PF03357.16 EJS42853.1 - 5.6e-15 55.1 19.3 8e-15 54.6 13.4 1.2 1 0 0 1 1 1 1 Snf7 DUF2580 PF10824.3 EJS42853.1 - 0.03 14.6 0.3 0.08 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) GrpE PF01025.14 EJS42853.1 - 0.5 9.8 11.8 0.13 11.7 5.8 1.6 1 1 0 2 2 2 0 GrpE DUF948 PF06103.6 EJS42853.1 - 2.1 8.2 6.3 2.7 7.8 0.5 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3385 PF11865.3 EJS42853.1 - 3.2 7.6 6.4 9 6.1 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) SYCE1 PF15233.1 EJS42853.1 - 4.5 7.1 14.1 8.6 6.2 9.8 1.7 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 YlqD PF11068.3 EJS42853.1 - 8.8 6.3 16.2 3.1 7.8 6.1 2.5 1 1 1 2 2 2 0 YlqD protein Peptidase_M22 PF00814.20 EJS42854.1 - 1.3e-85 287.1 0.0 1.6e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 EJS42854.1 - 0.02 14.0 0.1 0.028 13.5 0.1 1.1 1 0 0 1 1 1 0 Carbamoyltransferase Staygreen PF12638.2 EJS42854.1 - 0.024 14.1 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Staygreen protein AA_permease PF00324.16 EJS42855.1 - 1.2e-152 508.6 37.6 1.4e-152 508.4 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS42855.1 - 2e-39 135.3 38.7 2.7e-39 134.9 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease His_Phos_1 PF00300.17 EJS42856.1 - 3e-28 98.8 0.1 4.1e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EJS42856.1 - 0.059 12.6 0.1 0.11 11.7 0.0 1.4 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Lectin_leg-like PF03388.8 EJS42857.1 - 1.5e-15 57.0 0.0 8.2e-07 28.3 0.0 2.2 2 0 0 2 2 2 2 Legume-like lectin family Lectin_legB PF00139.14 EJS42857.1 - 2.7e-05 23.6 0.2 7.6e-05 22.1 0.2 1.9 1 1 0 1 1 1 1 Legume lectin domain NAP PF00956.13 EJS42860.1 - 6.8e-78 261.1 8.0 6.8e-78 261.1 5.6 2.4 3 0 0 3 3 3 1 Nucleosome assembly protein (NAP) Nop14 PF04147.7 EJS42860.1 - 1.5 6.6 22.5 2.9 5.6 15.6 1.5 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EJS42860.1 - 2.4 6.0 10.2 3.4 5.5 7.0 1.4 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EJS42860.1 - 9 5.4 12.4 18 4.4 8.6 1.5 1 0 0 1 1 1 0 NOA36 protein DUF1687 PF07955.6 EJS42861.1 - 4.5e-41 139.9 0.8 5.2e-41 139.7 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) TrkH PF02386.11 EJS42862.1 - 6.8e-145 482.0 12.3 2e-143 477.2 3.0 2.1 2 0 0 2 2 2 2 Cation transport protein PBP1_TM PF14812.1 EJS42862.1 - 0.08 13.2 2.7 1.8 8.9 0.0 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_carr PF00153.22 EJS42863.1 - 1e-62 207.8 2.1 1.8e-21 75.6 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein PAP2 PF01569.16 EJS42864.1 - 2.1e-12 46.8 3.8 4.6e-12 45.7 2.7 1.5 1 0 0 1 1 1 1 PAP2 superfamily Fer4_5 PF12801.2 EJS42864.1 - 0.0084 15.8 1.1 0.0084 15.8 0.8 2.7 4 0 0 4 4 4 1 4Fe-4S binding domain DHC_N1 PF08385.7 EJS42865.1 - 9e-101 338.0 25.8 9e-101 338.0 17.9 5.9 5 1 1 6 6 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EJS42865.1 - 2.9e-91 306.0 17.9 2.9e-91 306.0 12.4 5.0 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EJS42865.1 - 6.8e-60 202.4 0.0 1.8e-59 201.0 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 Dynein_heavy PF03028.10 EJS42865.1 - 1.6e-33 115.7 0.0 1.6e-33 115.7 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_5 PF07728.9 EJS42865.1 - 1.6e-29 102.4 0.3 2.7e-10 40.0 0.0 6.7 6 1 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 EJS42865.1 - 2e-28 99.1 0.2 7.4e-28 97.2 0.1 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EJS42865.1 - 1.2e-24 86.7 8.2 2.2e-24 85.8 5.7 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 EJS42865.1 - 1.3e-23 83.0 0.7 4.1e-23 81.4 0.5 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA PF00004.24 EJS42865.1 - 1.5e-17 64.0 3.4 0.00029 21.0 0.0 7.4 7 0 0 7 7 6 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EJS42865.1 - 1.2e-15 57.7 9.4 0.00013 22.1 0.0 7.7 6 1 1 7 7 6 4 AAA domain AAA_16 PF13191.1 EJS42865.1 - 1.1e-11 45.0 0.2 0.3 11.0 0.0 5.8 5 1 1 6 6 6 3 AAA ATPase domain Zeta_toxin PF06414.7 EJS42865.1 - 6.5e-09 35.1 0.0 0.016 14.3 0.0 4.3 4 0 0 4 4 4 2 Zeta toxin AAA_17 PF13207.1 EJS42865.1 - 1.7e-08 35.2 0.4 0.38 11.5 0.0 5.5 4 0 0 4 4 3 3 AAA domain AAA_33 PF13671.1 EJS42865.1 - 1.1e-07 31.8 0.1 0.31 10.9 0.0 4.7 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EJS42865.1 - 5.7e-07 29.3 0.3 1.6 8.2 0.0 4.7 4 1 0 4 4 4 2 AAA domain AAA_19 PF13245.1 EJS42865.1 - 9.1e-07 28.5 0.5 2.7 7.8 0.0 4.5 4 0 0 4 4 4 1 Part of AAA domain RNA_helicase PF00910.17 EJS42865.1 - 3.5e-06 27.1 0.2 4.8 7.3 0.0 5.3 4 0 0 4 4 4 1 RNA helicase AAA_18 PF13238.1 EJS42865.1 - 2.8e-05 24.4 9.6 1.5 9.1 0.0 6.3 6 0 0 6 6 5 2 AAA domain IstB_IS21 PF01695.12 EJS42865.1 - 3.5e-05 23.2 0.2 0.29 10.5 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EJS42865.1 - 7.7e-05 22.2 0.5 3.7 6.9 0.0 4.5 4 0 0 4 4 4 1 FtsK/SpoIIIE family AAA_28 PF13521.1 EJS42865.1 - 0.00026 21.0 0.6 1.9 8.3 0.0 4.1 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 EJS42865.1 - 0.005 16.2 0.3 14 5.0 0.0 4.4 5 0 0 5 5 5 0 AAA domain Mg_chelatase PF01078.16 EJS42865.1 - 0.0062 15.7 1.3 0.66 9.0 0.0 3.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EJS42865.1 - 0.026 14.2 9.2 1.4 8.5 0.0 5.2 6 0 0 6 6 5 0 NACHT domain Ras PF00071.17 EJS42866.1 - 1.3e-50 170.9 0.0 1.6e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS42866.1 - 1.1e-17 64.6 0.0 1.8e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS42866.1 - 5.9e-06 25.6 0.0 1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EJS42866.1 - 0.093 11.8 0.0 0.12 11.5 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Glyco_transf_8 PF01501.15 EJS42867.1 - 1.9e-35 122.3 0.0 4e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 NDK PF00334.14 EJS42868.1 - 7.1e-56 187.7 0.0 8.2e-56 187.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Bap31 PF05529.7 EJS42870.1 - 2.7e-55 186.8 5.1 3.1e-55 186.6 3.5 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TACC PF05010.9 EJS42870.1 - 0.0011 18.8 7.5 0.0015 18.3 5.2 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) BLOC1_2 PF10046.4 EJS42870.1 - 0.0068 16.5 4.2 0.011 15.8 2.9 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Potyvirid-P3 PF13608.1 EJS42870.1 - 0.0083 15.3 0.6 0.0093 15.1 0.4 1.2 1 0 0 1 1 1 1 Protein P3 of Potyviral polyprotein Mem_trans PF03547.13 EJS42870.1 - 0.0096 14.2 0.5 0.013 13.8 0.2 1.4 1 1 0 1 1 1 1 Membrane transport protein Sec2p PF06428.6 EJS42870.1 - 0.012 15.4 7.4 0.018 14.8 5.1 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p IFT20 PF14931.1 EJS42870.1 - 0.036 13.9 3.3 0.054 13.3 2.3 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 IncA PF04156.9 EJS42870.1 - 0.041 13.4 0.3 0.041 13.4 0.2 1.6 2 0 0 2 2 1 0 IncA protein Rpp20 PF12328.3 EJS42870.1 - 0.054 13.1 3.6 0.081 12.5 2.5 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF2250 PF10007.4 EJS42870.1 - 0.09 12.6 1.5 0.15 12.0 0.3 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Tektin PF03148.9 EJS42870.1 - 0.12 10.8 5.1 0.17 10.4 3.6 1.1 1 0 0 1 1 1 0 Tektin family Seryl_tRNA_N PF02403.17 EJS42870.1 - 0.57 10.2 8.6 0.86 9.6 6.0 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EF-hand_like PF09279.6 EJS42870.1 - 0.7 9.9 3.9 0.74 9.8 1.5 1.9 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Anoctamin PF04547.7 EJS42870.1 - 3.6 6.1 8.9 0.81 8.2 0.5 2.1 1 1 0 2 2 2 0 Calcium-activated chloride channel Pex24p PF06398.6 EJS42870.1 - 6.7 5.4 8.1 36 2.9 5.6 2.1 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin NAM-associated PF14303.1 EJS42871.1 - 0.00043 20.6 9.4 0.00052 20.3 6.5 1.1 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Ycf1 PF05758.7 EJS42871.1 - 0.071 10.8 8.1 0.079 10.6 5.6 1.0 1 0 0 1 1 1 0 Ycf1 Attacin_N PF03768.10 EJS42871.1 - 0.33 10.8 2.1 0.46 10.3 0.8 1.7 2 0 0 2 2 2 0 Attacin, N-terminal region Presenilin PF01080.12 EJS42871.1 - 1.9 7.2 3.7 2.3 6.9 2.5 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.9 EJS42871.1 - 5.8 6.5 12.8 7.3 6.2 8.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-C2H2 PF00096.21 EJS42872.1 - 2.6e-08 33.7 12.5 1.9e-06 27.8 1.9 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EJS42872.1 - 4.2e-07 29.9 19.0 7.3e-06 26.0 2.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EJS42872.1 - 1.5e-06 28.0 20.8 4.9e-05 23.3 1.7 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.10 EJS42872.1 - 2.2e-05 24.1 5.7 0.028 14.1 0.3 2.7 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.3 EJS42872.1 - 0.00089 19.3 9.6 0.14 12.3 1.9 3.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EJS42872.1 - 0.0076 16.4 6.0 1.4 9.2 0.9 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EJS42872.1 - 0.057 13.3 7.0 0.2 11.5 0.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger GAGA PF09237.6 EJS42872.1 - 0.089 12.3 2.5 6.5 6.4 0.1 3.1 2 1 1 3 3 3 0 GAGA factor zf-LYAR PF08790.6 EJS42872.1 - 0.69 9.6 3.7 13 5.6 0.1 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF629 PF04780.7 EJS42872.1 - 1.1 7.7 7.5 7 5.0 4.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF629) PHA_gran_rgn PF09650.5 EJS42873.1 - 0.0011 19.0 0.5 0.053 13.6 0.1 2.1 1 1 1 2 2 2 1 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) ComJ PF11033.3 EJS42873.1 - 0.063 12.9 0.1 0.073 12.7 0.1 1.2 1 0 0 1 1 1 0 Competence protein J (ComJ) Streptin-Immun PF11083.3 EJS42873.1 - 0.31 11.0 6.1 0.3 11.0 3.2 1.7 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein IncA PF04156.9 EJS42873.1 - 0.6 9.6 7.1 0.83 9.2 4.9 1.3 1 0 0 1 1 1 0 IncA protein Med28 PF11594.3 EJS42873.1 - 0.83 9.9 7.0 1.7 8.9 4.9 1.6 1 1 0 1 1 1 0 Mediator complex subunit 28 F_bP_aldolase PF01116.15 EJS42874.1 - 7.4e-92 307.4 0.0 8.3e-92 307.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DWNN PF08783.6 EJS42875.1 - 5.8e-32 109.4 1.6 1.4e-31 108.2 0.1 2.2 2 0 0 2 2 2 1 DWNN domain zf-Nse PF11789.3 EJS42875.1 - 0.00032 20.1 0.4 0.00077 18.9 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EJS42875.1 - 0.00049 20.0 0.2 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 U-box domain zf-CCHC PF00098.18 EJS42875.1 - 0.0028 17.5 3.8 0.0028 17.5 2.6 2.0 2 0 0 2 2 2 1 Zinc knuckle Rubredoxin PF00301.15 EJS42875.1 - 0.0042 16.9 5.2 0.24 11.3 0.0 3.2 3 0 0 3 3 3 2 Rubredoxin zf-CCHC_2 PF13696.1 EJS42875.1 - 0.0063 15.9 3.9 0.0063 15.9 2.7 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 EJS42875.1 - 0.03 14.0 0.1 0.065 12.9 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EJS42875.1 - 0.064 12.7 0.6 0.15 11.5 0.4 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-DNL PF05180.7 EJS42875.1 - 0.083 12.6 1.5 0.11 12.2 0.2 1.9 2 0 0 2 2 2 0 DNL zinc finger TF_Zn_Ribbon PF08271.7 EJS42875.1 - 2.3 7.6 6.8 0.89 8.9 0.5 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding TFIIA_gamma_C PF02751.9 EJS42876.1 - 1.9e-27 94.8 0.6 2.9e-27 94.2 0.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EJS42876.1 - 2.4e-25 87.8 0.2 3.2e-25 87.4 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TCTP PF00838.12 EJS42878.1 - 2.6e-73 245.4 3.0 2.9e-73 245.2 2.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein CUE PF02845.11 EJS42879.1 - 1.3e-05 24.5 0.0 2.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 CUE domain UPF0203 PF05254.7 EJS42880.1 - 8.3e-31 105.6 3.0 9.7e-31 105.4 2.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EJS42880.1 - 0.0037 17.0 1.8 0.75 9.6 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like PaREP1 PF05942.6 EJS42880.1 - 0.016 15.0 0.2 0.019 14.8 0.1 1.1 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family UCR_hinge PF02320.11 EJS42880.1 - 0.11 12.4 3.6 1.2 9.1 2.5 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 EJS42880.1 - 1.2 9.2 6.9 4.3 7.4 0.8 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DASH_Ask1 PF08655.5 EJS42881.1 - 2.4e-29 100.9 0.1 4.7e-29 100.0 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 PBP1_TM PF14812.1 EJS42881.1 - 6.2 7.2 10.0 15 5.9 1.4 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Frag1 PF10277.4 EJS42882.1 - 1.9e-82 275.9 26.5 2.2e-82 275.6 18.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family PBP_sp32 PF07222.7 EJS42882.1 - 0.17 11.0 0.1 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF4173 PF13777.1 EJS42882.1 - 0.85 8.8 13.4 3.5 6.8 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4173) DUF2207 PF09972.4 EJS42882.1 - 0.9 8.0 5.3 2.4 6.6 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3812 PF12757.2 EJS42883.1 - 7.2e-26 90.6 0.5 7.2e-26 90.6 0.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3812) Histone PF00125.19 EJS42884.1 - 1e-26 92.8 0.3 1e-26 92.8 0.2 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EJS42884.1 - 0.0022 18.1 0.1 0.0045 17.1 0.1 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S DUF2347 PF09804.4 EJS42885.1 - 1.6e-75 254.0 0.9 2.3e-75 253.4 0.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EJS42885.1 - 9.2e-17 61.6 0.2 7e-13 49.0 0.2 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 EJS42885.1 - 1.3e-08 33.7 0.6 3.6e-07 28.9 0.4 2.5 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EJS42885.1 - 9.9e-08 31.6 0.0 3.1e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 EJS42885.1 - 0.044 13.7 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Glyco_hydro_76 PF03663.9 EJS42886.1 - 4.6e-153 509.9 26.1 5.8e-153 509.6 18.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DNA_primase_lrg PF04104.9 EJS42887.1 - 8.3e-86 287.4 0.1 1.4e-85 286.7 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit KilA-N PF04383.8 EJS42888.1 - 2.9e-05 23.6 0.1 9.9e-05 21.9 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain Spc42p PF11544.3 EJS42889.1 - 1.6e-24 85.5 13.6 1.6e-24 85.5 9.4 3.2 2 1 1 3 3 3 1 Spindle pole body component Spc42p DUF4116 PF13475.1 EJS42889.1 - 0.011 15.2 1.2 0.018 14.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Lsr2 PF11774.3 EJS42889.1 - 0.053 13.4 0.8 0.12 12.3 0.5 1.6 1 0 0 1 1 1 0 Lsr2 Pox_A_type_inc PF04508.7 EJS42889.1 - 0.39 10.6 5.2 15 5.6 0.1 3.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF724 PF05266.9 EJS42889.1 - 8.2 6.0 16.6 3.2 7.3 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Snf7 PF03357.16 EJS42890.1 - 7.4e-36 123.0 14.6 7.4e-36 123.0 10.1 1.6 1 1 1 2 2 2 1 Snf7 PAS_7 PF12860.2 EJS42890.1 - 0.00086 19.2 2.5 0.61 10.1 0.1 3.1 1 1 2 3 3 3 2 PAS fold Eno-Rase_FAD_bd PF07055.7 EJS42890.1 - 0.068 13.1 1.3 0.18 11.7 0.1 2.4 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain DUF2096 PF09869.4 EJS42890.1 - 1.1 9.1 8.5 0.15 11.9 1.7 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) MutS_III PF05192.13 EJS42890.1 - 1.5 8.5 7.2 4.5 6.9 5.0 1.7 1 1 0 1 1 1 0 MutS domain III Tox-REase-2 PF15646.1 EJS42890.1 - 4.4 7.1 7.9 0.85 9.4 1.2 2.4 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 2 Zn_clus PF00172.13 EJS42891.1 - 7.6e-10 38.5 13.0 1.4e-09 37.7 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGP PF01704.13 EJS42892.1 - 1.3e-194 646.5 0.0 1.6e-194 646.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 EJS42892.1 - 0.0065 15.0 0.6 0.021 13.4 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4301) zf-RING_2 PF13639.1 EJS42893.1 - 3.9e-11 42.6 6.3 7.6e-11 41.6 4.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EJS42893.1 - 3.9e-09 36.4 4.2 7.1e-09 35.6 2.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EJS42893.1 - 4.3e-07 29.5 4.6 7.2e-07 28.8 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EJS42893.1 - 4.6e-07 29.4 4.1 8.6e-07 28.5 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EJS42893.1 - 2.8e-05 23.6 6.8 5.6e-05 22.7 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EJS42893.1 - 6.5e-05 22.8 6.3 0.00029 20.7 4.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EJS42893.1 - 0.00094 18.9 1.5 0.0019 18.0 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EJS42893.1 - 0.004 16.8 0.7 0.014 15.1 0.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 EJS42893.1 - 0.028 14.3 4.6 0.084 12.8 3.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.9 EJS42893.1 - 2.3 7.7 6.6 0.72 9.3 2.3 1.8 2 0 0 2 2 2 0 P-11 zinc finger RINGv PF12906.2 EJS42893.1 - 3.9 7.6 7.1 0.73 9.9 2.2 1.8 2 0 0 2 2 2 0 RING-variant domain HAD_2 PF13419.1 EJS42894.1 - 1.3e-19 71.0 0.0 1.6e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EJS42894.1 - 6e-10 39.8 0.0 3.7e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EJS42894.1 - 0.00035 20.3 0.0 0.092 12.6 0.0 2.6 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EJS42894.1 - 0.0028 17.8 0.0 0.0031 17.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EJS42894.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like HMG_box PF00505.14 EJS42895.1 - 4e-34 116.6 7.6 1.7e-17 63.4 1.4 3.6 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EJS42895.1 - 5.5e-16 58.6 4.2 5.9e-11 42.5 1.1 3.6 3 1 0 3 3 3 2 HMG-box domain CHDNT PF08073.7 EJS42895.1 - 3.4e-05 23.4 0.0 0.046 13.4 0.0 2.5 2 0 0 2 2 2 2 CHDNT (NUC034) domain Malic_M PF03949.10 EJS42896.1 - 1.1e-77 261.0 0.0 1.6e-77 260.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EJS42896.1 - 2.4e-63 213.0 0.1 8e-63 211.3 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.15 EJS42896.1 - 0.14 12.2 0.4 16 5.6 0.1 3.3 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EJS42897.1 - 1.2e-36 125.5 0.0 2e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EJS42897.1 - 0.00018 21.5 0.0 0.00039 20.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EJS42897.1 - 0.0056 15.6 0.6 0.045 12.7 0.4 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EJS42897.1 - 0.0098 15.8 0.2 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.1 EJS42897.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EJS42897.1 - 0.067 12.6 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HIGH_NTase1 PF05636.6 EJS42898.1 - 0.064 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase ADK PF00406.17 EJS42899.1 - 3.9e-49 166.3 0.0 5.1e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EJS42899.1 - 1.2e-09 38.5 0.2 2.6e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EJS42899.1 - 2.2e-08 34.9 0.0 3.8e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EJS42899.1 - 2.7e-08 33.7 0.0 5.4e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EJS42899.1 - 3.9e-07 29.6 0.3 0.0084 15.5 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 EJS42899.1 - 0.0002 20.5 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Dfp1_Him1_M PF08630.5 EJS42899.1 - 0.044 13.5 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Dfp1/Him1, central region AAA PF00004.24 EJS42899.1 - 0.09 12.9 0.2 0.34 11.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPSase_L_D3 PF02787.14 EJS42899.1 - 0.1 12.3 0.1 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain PPTA PF01239.17 EJS42900.1 - 1.4e-38 128.6 18.1 7.1e-08 31.4 0.2 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF1748 PF08520.5 EJS42901.1 - 2.7e-19 68.5 0.2 3.5e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WD40 PF00400.27 EJS42902.1 - 2.1e-17 62.2 1.0 8e-05 22.3 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat AAA_12 PF13087.1 EJS42903.1 - 5.3e-58 195.7 0.0 5.3e-58 195.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EJS42903.1 - 1.3e-55 188.6 0.7 1.3e-55 188.6 0.5 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EJS42903.1 - 1.6e-13 50.1 0.0 1.3e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EJS42903.1 - 1.1e-12 48.0 0.2 0.0017 17.9 0.0 3.6 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EJS42903.1 - 5.7e-09 35.8 0.0 1.8e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EJS42903.1 - 1.7e-07 30.6 0.0 4.3e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.10 EJS42903.1 - 3.1e-06 27.1 0.2 3.1e-06 27.1 0.1 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EJS42903.1 - 1.7e-05 23.9 2.1 0.00082 18.4 1.5 2.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EJS42903.1 - 2.8e-05 23.6 0.7 0.00021 20.8 0.4 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 EJS42903.1 - 0.0001 21.7 0.6 0.0001 21.7 0.4 3.3 3 1 1 4 4 4 1 UvrD/REP helicase N-terminal domain AAA_14 PF13173.1 EJS42903.1 - 0.00014 21.7 2.5 0.053 13.4 0.0 3.3 4 1 0 4 4 2 2 AAA domain AAA_22 PF13401.1 EJS42903.1 - 0.00027 21.0 0.0 0.0017 18.5 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_23 PF13476.1 EJS42903.1 - 0.00052 20.3 0.4 0.00052 20.3 0.3 3.6 1 1 1 3 3 3 1 AAA domain AAA_25 PF13481.1 EJS42903.1 - 0.0011 18.4 0.0 0.0028 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EJS42903.1 - 0.0025 17.9 0.0 0.0087 16.1 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 EJS42903.1 - 0.0027 17.3 0.0 0.012 15.2 0.0 2.3 2 1 0 2 2 2 1 Helicase AAA_16 PF13191.1 EJS42903.1 - 0.0053 16.7 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EJS42903.1 - 0.015 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 EJS42903.1 - 0.017 15.3 0.1 0.054 13.7 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EJS42903.1 - 0.029 14.5 0.2 0.2 11.8 0.0 2.6 3 0 0 3 3 2 0 RNA helicase T2SE PF00437.15 EJS42903.1 - 0.031 13.1 0.1 0.065 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 EJS42903.1 - 0.04 14.7 2.2 0.5 11.1 1.5 2.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EJS42903.1 - 0.061 13.1 0.1 0.19 11.5 0.0 2.0 2 1 0 2 2 1 0 AAA domain NACHT PF05729.7 EJS42903.1 - 0.069 12.8 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain GTP_EFTU_D2 PF03144.20 EJS42903.1 - 0.1 12.7 1.5 0.23 11.6 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Mt_ATP-synt_D PF05873.7 EJS42904.1 - 2.2e-15 56.6 3.4 2.8e-15 56.3 2.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) eRF1_1 PF03463.10 EJS42904.1 - 0.023 14.2 0.5 0.043 13.4 0.4 1.5 1 1 0 1 1 1 0 eRF1 domain 1 LTXXQ PF07813.7 EJS42904.1 - 0.031 14.7 0.1 3.3 8.2 0.0 2.1 2 0 0 2 2 2 0 LTXXQ motif family protein T5orf172 PF10544.4 EJS42904.1 - 0.083 13.2 0.4 0.14 12.5 0.3 1.6 1 1 0 1 1 1 0 T5orf172 domain CEP19 PF14933.1 EJS42904.1 - 0.12 12.6 2.8 0.16 12.2 1.9 1.1 1 0 0 1 1 1 0 CEP19-like protein ASL_C2 PF14698.1 EJS42904.1 - 0.21 11.7 0.7 1.4 9.0 0.0 2.5 2 1 1 3 3 3 0 Argininosuccinate lyase C-terminal V-ATPase_H_N PF03224.9 EJS42904.1 - 0.34 9.9 4.6 0.24 10.5 0.2 2.0 1 1 1 2 2 2 0 V-ATPase subunit H IncA PF04156.9 EJS42904.1 - 3.5 7.1 6.8 7.3 6.1 4.7 1.5 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 EJS42904.1 - 8.2 6.4 10.2 14 5.6 0.4 2.2 1 1 1 2 2 2 0 FlxA-like protein Fungal_trans PF04082.13 EJS42905.1 - 5.7e-28 97.4 4.6 6.8e-28 97.2 2.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS42905.1 - 5.9e-10 38.8 7.3 1e-09 38.1 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Npa1 PF11707.3 EJS42906.1 - 3e-103 345.2 9.1 9.4e-103 343.6 6.3 1.9 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Thg1 PF04446.7 EJS42906.1 - 0.0089 15.6 0.6 0.03 13.9 0.4 1.9 1 0 0 1 1 1 1 tRNAHis guanylyltransferase ARPC4 PF05856.7 EJS42907.1 - 8.6e-72 240.0 4.0 9.5e-72 239.8 2.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FF PF01846.14 EJS42908.1 - 2.1e-44 149.2 26.7 1.5e-13 50.4 0.0 7.2 8 0 0 8 8 8 4 FF domain WW PF00397.21 EJS42908.1 - 6e-18 64.3 11.8 3.2e-10 39.6 0.9 2.8 2 0 0 2 2 2 2 WW domain CARD PF00619.16 EJS42908.1 - 0.041 13.7 2.1 2.9 7.8 0.0 3.9 4 0 0 4 4 4 0 Caspase recruitment domain Hydrolase_2 PF07486.7 EJS42908.1 - 7.7 7.0 6.7 31 5.1 0.2 3.3 3 1 1 4 4 4 0 Cell Wall Hydrolase Ydc2-catalyt PF09159.5 EJS42909.1 - 2e-53 181.6 4.3 2.6e-53 181.3 3.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EJS42909.1 - 0.00047 20.0 0.2 0.32 10.8 0.0 2.9 2 1 0 2 2 2 2 Poxvirus A22 protein HECT PF00632.20 EJS42910.1 - 2.7e-71 240.3 0.1 4.6e-71 239.5 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L10 PF00466.15 EJS42911.1 - 1.2e-20 73.2 0.0 1.9e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3538 PF12057.3 EJS42911.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) TRAM_LAG1_CLN8 PF03798.11 EJS42912.1 - 2.1e-32 112.2 25.9 2.1e-32 112.2 17.9 2.1 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EJS42912.1 - 2.5e-25 87.7 1.8 7e-25 86.3 1.3 1.8 1 0 0 1 1 1 1 TRAM1-like protein MOSP_C PF02722.10 EJS42912.1 - 0.012 15.2 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal region F-actin_cap_A PF01267.12 EJS42913.1 - 7.3e-80 267.8 1.7 8.4e-80 267.7 1.2 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit COG6 PF06419.6 EJS42913.1 - 0.0055 14.9 0.0 0.0077 14.4 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 PAP2 PF01569.16 EJS42914.1 - 2.7e-12 46.4 6.7 2.7e-12 46.4 4.6 2.3 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EJS42914.1 - 0.002 17.7 8.5 0.002 17.7 5.9 2.1 2 1 0 2 2 2 1 PAP2 superfamily Ribosomal_S6 PF01250.12 EJS42915.1 - 1.3e-06 28.1 0.1 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 RTP801_C PF07809.6 EJS42915.1 - 0.06 13.0 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 RTP801 C-terminal region APS_kinase PF01583.15 EJS42916.1 - 5e-74 247.1 0.0 6e-74 246.9 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EJS42916.1 - 2.1e-08 34.1 0.0 3.9e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EJS42916.1 - 9.1e-06 26.5 0.1 1.3e-05 25.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EJS42916.1 - 9.2e-05 21.7 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EJS42916.1 - 0.00012 22.3 0.1 0.00023 21.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EJS42916.1 - 0.00017 21.0 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain CPT PF07931.7 EJS42916.1 - 0.0052 16.4 0.3 0.25 10.9 0.2 2.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 EJS42916.1 - 0.017 15.4 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EJS42916.1 - 0.018 14.9 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EJS42916.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EJS42916.1 - 0.083 13.1 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EJS42916.1 - 0.089 11.8 0.0 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 EJS42916.1 - 0.099 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_M PF01031.15 EJS42917.1 - 1e-106 356.0 0.2 1e-106 356.0 0.2 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EJS42917.1 - 6.9e-58 195.1 0.2 1.9e-57 193.7 0.1 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EJS42917.1 - 3.6e-27 94.1 5.1 1.1e-26 92.5 3.5 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EJS42917.1 - 0.00098 19.0 0.4 0.031 14.2 0.3 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EJS42917.1 - 0.023 15.2 0.0 0.069 13.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein PAP_central PF04928.12 EJS42918.1 - 1.6e-106 354.7 0.0 4.7e-106 353.2 0.0 1.7 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EJS42918.1 - 1.4e-47 161.0 0.5 2.4e-47 160.3 0.4 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EJS42918.1 - 6.4e-12 45.6 0.1 2e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Rifin_STEVOR PF02009.11 EJS42919.1 - 0.0012 18.5 0.3 0.0018 18.0 0.2 1.3 1 0 0 1 1 1 1 Rifin/stevor family Pox_Ag35 PF03286.9 EJS42919.1 - 0.047 13.2 4.2 0.12 11.8 2.9 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_L50 PF10501.4 EJS42920.1 - 2.2e-23 82.3 0.5 2.2e-23 82.3 0.3 2.1 2 1 1 3 3 3 1 Ribosomal subunit 39S DUF2605 PF10792.4 EJS42920.1 - 0.019 14.6 0.8 4.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) Syntaxin_2 PF14523.1 EJS42920.1 - 0.024 14.6 0.2 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Syntaxin-like protein LAMTOR PF15454.1 EJS42921.1 - 6.6e-14 51.9 2.7 6.6e-14 51.9 1.8 1.9 2 1 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator T2SS-T3SS_pil_N PF13629.1 EJS42921.1 - 0.062 12.8 0.1 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Pilus formation protein N terminal region Bromodomain PF00439.20 EJS42922.1 - 1.2e-30 105.2 7.1 1.2e-18 66.8 0.3 2.7 2 0 0 2 2 2 2 Bromodomain adh_short PF00106.20 EJS42923.1 - 6.8e-65 218.0 4.5 9.3e-32 110.2 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EJS42923.1 - 1.7e-34 117.8 0.0 3.3e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EJS42923.1 - 1.6e-33 115.8 0.7 1.9e-15 56.9 0.3 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EJS42923.1 - 6.4e-20 71.9 0.6 2.8e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 EJS42923.1 - 8.1e-06 25.6 0.0 4.1e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase DUF2099 PF09872.4 EJS42923.1 - 0.1 11.6 0.1 0.26 10.2 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2099) 3HCDH_N PF02737.13 EJS42923.1 - 0.78 9.3 6.1 2.1 7.9 0.0 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ndr PF03096.9 EJS42924.1 - 0.083 11.3 1.2 0.14 10.5 0.8 1.4 1 0 0 1 1 1 0 Ndr family CAP PF00188.21 EJS42925.1 - 2.1e-17 63.7 3.7 4e-17 62.8 2.6 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TFIIA PF03153.8 EJS42925.1 - 2.1 8.1 15.8 2.7 7.7 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3306 PF11748.3 EJS42925.1 - 2.9 8.5 12.1 59 4.3 8.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) Ras PF00071.17 EJS42926.1 - 3.4e-54 182.6 0.1 4.5e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS42926.1 - 6.5e-21 75.0 0.1 1.4e-20 73.9 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EJS42926.1 - 2.6e-12 46.3 0.1 5.1e-12 45.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EJS42926.1 - 2.6e-05 23.4 0.0 4.5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EJS42926.1 - 0.00012 22.0 0.0 0.0002 21.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EJS42926.1 - 0.00047 19.6 0.0 0.00093 18.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EJS42926.1 - 0.037 13.2 0.2 0.095 11.8 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EJS42926.1 - 0.049 13.6 0.2 0.11 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain adh_short_C2 PF13561.1 EJS42926.1 - 0.058 13.1 0.1 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF3808 PF10300.4 EJS42928.1 - 1.3e-173 577.9 0.5 1.5e-173 577.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 EJS42928.1 - 0.0023 18.5 2.2 0.58 10.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EJS42928.1 - 0.11 12.3 2.3 14 5.5 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EJS42928.1 - 1.9 9.1 5.4 9.9 6.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EJS42928.1 - 4.4 7.7 9.3 3.7 7.9 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat EF-hand_4 PF12763.2 EJS42929.1 - 0.0041 16.8 0.0 0.019 14.6 0.0 2.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Vps51 PF08700.6 EJS42930.1 - 1.1e-11 44.4 1.9 2.2e-11 43.4 1.3 1.6 1 0 0 1 1 1 1 Vps51/Vps67 HBS1_N PF08938.5 EJS42930.1 - 0.0076 16.3 1.5 0.012 15.7 1.0 1.6 1 1 0 1 1 1 1 HBS1 N-terminus Arrestin_C PF02752.17 EJS42931.1 - 2.6e-16 59.9 0.6 2.5e-14 53.5 0.0 2.9 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EJS42931.1 - 3.2e-07 30.2 0.2 0.00073 19.3 0.1 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain NTR2 PF15458.1 EJS42932.1 - 3.7e-44 150.8 15.1 5e-44 150.4 10.5 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DEAD PF00270.24 EJS42933.1 - 2.2e-40 137.9 0.0 4.3e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EJS42933.1 - 1.8e-19 68.9 0.0 6e-19 67.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EJS42933.1 - 1.7e-17 63.0 0.0 4e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EJS42933.1 - 2.2e-05 24.3 0.2 5.9e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EJS42933.1 - 0.021 13.6 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain IF-2B PF01008.12 EJS42934.1 - 1e-81 274.0 0.0 1.1e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 EJS42934.1 - 0.044 13.4 0.1 4.4 6.9 0.0 2.5 2 0 0 2 2 2 0 DeoR C terminal sensor domain GAF_2 PF13185.1 EJS42935.1 - 5.9e-09 36.5 0.0 1e-08 35.8 0.0 1.5 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EJS42935.1 - 0.0018 18.4 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 GAF domain DUF4007 PF13182.1 EJS42936.1 - 0.007 15.2 0.0 0.0087 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4007) Metallophos PF00149.23 EJS42937.1 - 1.3e-12 47.5 4.3 1.3e-12 47.5 3.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DBR1 PF05011.8 EJS42937.1 - 3.3e-09 36.7 1.0 4.8e-09 36.2 0.3 1.6 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Usg PF06233.7 EJS42937.1 - 0.043 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Usg-like family FAD_binding_2 PF00890.19 EJS42938.1 - 2.9e-124 415.1 2.4 3.7e-124 414.7 1.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EJS42938.1 - 7.8e-47 158.3 0.8 7.8e-47 158.3 0.6 1.5 2 0 0 2 2 2 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EJS42938.1 - 4.8e-07 29.8 2.5 4.5e-05 23.4 1.2 2.9 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EJS42938.1 - 8.9e-07 28.0 0.5 0.00036 19.5 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EJS42938.1 - 1.2e-06 27.7 1.5 2.3e-05 23.5 1.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EJS42938.1 - 0.00013 21.1 0.2 0.008 15.2 0.1 2.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EJS42938.1 - 0.0079 14.7 0.8 0.035 12.5 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 EJS42938.1 - 0.01 14.9 1.2 0.018 14.0 0.1 2.0 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_3 PF13738.1 EJS42938.1 - 0.19 11.7 2.0 1.6 8.7 0.2 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Aa_trans PF01490.13 EJS42939.1 - 1.5e-103 346.4 30.4 1.8e-103 346.1 21.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein VID27 PF08553.5 EJS42939.1 - 1.6 6.8 2.7 2.3 6.3 1.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein AAA PF00004.24 EJS42940.1 - 3.6e-40 137.2 0.0 6.3e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EJS42940.1 - 5.4e-06 26.5 0.0 0.001 19.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EJS42940.1 - 2.9e-05 23.8 0.0 0.00012 21.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EJS42940.1 - 0.00013 22.0 0.0 0.0011 18.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EJS42940.1 - 0.00026 20.9 0.0 0.00058 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EJS42940.1 - 0.00086 20.1 0.1 0.003 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EJS42940.1 - 0.0012 17.8 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EJS42940.1 - 0.0036 16.3 0.0 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EJS42940.1 - 0.0065 16.1 0.2 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EJS42940.1 - 0.0099 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EJS42940.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EJS42940.1 - 0.014 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EJS42940.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EJS42940.1 - 0.023 15.0 0.1 0.062 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EJS42940.1 - 0.024 14.8 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EJS42940.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 EJS42940.1 - 0.036 13.6 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EJS42940.1 - 0.038 14.0 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EJS42940.1 - 0.046 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EJS42940.1 - 0.047 12.4 0.0 0.082 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 EJS42940.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol_Rbc25 PF08292.7 EJS42941.1 - 1.2e-45 154.6 0.2 1.6e-45 154.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EJS42941.1 - 1.3e-20 73.3 0.0 2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 LTV PF04180.9 EJS42942.1 - 1.7e-159 531.8 35.5 2e-159 531.6 24.6 1.0 1 0 0 1 1 1 1 Low temperature viability protein DUF3294 PF07957.6 EJS42943.1 - 1.3e-87 292.8 4.4 1.5e-87 292.6 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) CTP_transf_3 PF02348.14 EJS42943.1 - 0.088 12.4 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Tricorn_C1 PF14684.1 EJS42943.1 - 0.095 12.5 0.2 2.6 7.9 0.0 2.6 3 0 0 3 3 3 0 Tricorn protease C1 domain DUF904 PF06005.7 EJS42943.1 - 3.9 7.8 7.7 1e+02 3.3 5.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Sdh_cyt PF01127.17 EJS42944.1 - 3.1e-20 72.2 4.6 4.2e-20 71.7 3.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Abhydrolase_1 PF00561.15 EJS42945.1 - 1.2e-32 113.3 0.0 1.5e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EJS42945.1 - 7.1e-22 76.5 0.1 1.2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EJS42945.1 - 5.7e-06 26.3 0.0 1.3e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EJS42945.1 - 6.3e-05 22.7 0.0 0.00061 19.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EJS42945.1 - 0.00052 19.5 0.1 0.14 11.5 0.0 2.5 3 0 0 3 3 3 2 Serine hydrolase (FSH1) Ndr PF03096.9 EJS42945.1 - 0.0015 17.0 0.1 0.1 11.0 0.0 2.2 2 0 0 2 2 2 2 Ndr family Abhydrolase_2 PF02230.11 EJS42945.1 - 0.0032 16.9 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase L31 PF09784.4 EJS42946.1 - 2.9e-45 152.5 5.4 3.8e-45 152.1 3.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 WBS_methylT PF12589.3 EJS42946.1 - 0.024 15.1 1.9 0.024 15.1 1.3 1.7 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Cmc1 PF08583.5 EJS42947.1 - 2e-19 69.1 4.5 2.6e-19 68.7 3.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Acetyltransf_CG PF14542.1 EJS42947.1 - 0.0099 15.7 0.2 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF4434 PF14488.1 EJS42947.1 - 0.016 14.9 0.1 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Pterin_4a PF01329.14 EJS42947.1 - 0.028 14.1 0.1 0.031 14.0 0.0 1.4 1 1 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase CHCH PF06747.8 EJS42947.1 - 0.29 11.1 5.5 1.1 9.2 0.3 2.0 1 1 1 2 2 2 0 CHCH domain Adaptin_N PF01602.15 EJS42948.1 - 4.8e-138 460.7 22.6 5.8e-138 460.4 15.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EJS42948.1 - 2.8e-20 72.9 4.2 2.8e-20 72.9 2.9 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EJS42948.1 - 1.6e-11 44.2 1.5 1.1e-06 28.7 0.1 4.8 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EJS42948.1 - 1.5e-06 27.7 6.6 0.13 12.3 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EJS42948.1 - 0.016 15.6 1.4 62 4.2 0.0 4.3 3 1 0 3 3 3 0 HEAT-like repeat Arm PF00514.18 EJS42948.1 - 0.76 9.7 3.9 2.6 8.0 0.3 3.6 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat She2p PF11435.3 EJS42949.1 - 1.1e-96 322.0 6.0 1.3e-96 321.8 4.1 1.0 1 0 0 1 1 1 1 RNA binding protein She2p Myosin_head PF00063.16 EJS42950.1 - 1.5e-219 730.5 7.9 2.5e-219 729.8 5.4 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EJS42950.1 - 4.3e-49 166.5 1.3 1.3e-47 161.7 0.2 2.7 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 EJS42950.1 - 9e-11 41.0 0.0 1.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EJS42950.1 - 1.8e-05 24.2 0.0 4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EJS42950.1 - 0.0018 17.7 0.0 0.0042 16.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EJS42950.1 - 0.0054 16.8 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EJS42950.1 - 0.045 14.5 0.0 0.31 11.8 0.0 2.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EJS42950.1 - 0.057 13.4 0.0 0.41 10.6 0.0 2.4 3 1 1 4 4 4 0 AAA ATPase domain Hpr_kinase_C PF07475.7 EJS42950.1 - 0.057 12.7 0.1 5 6.4 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_19 PF13245.1 EJS42950.1 - 0.065 12.9 0.0 0.26 11.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EJS42950.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain His_Phos_1 PF00300.17 EJS42951.1 - 1.8e-15 57.3 0.0 2.6e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PGM_PMM_I PF02878.11 EJS42952.1 - 7.3e-35 119.4 0.4 1.2e-34 118.7 0.0 1.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EJS42952.1 - 1.2e-25 89.6 0.0 2.4e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EJS42952.1 - 8.7e-11 42.0 0.0 2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EJS42952.1 - 1.8e-09 37.4 0.0 4.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.20 EJS42953.1 - 4.6e-68 229.1 0.0 7.2e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42953.1 - 1.4e-30 106.2 0.0 2.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EJS42953.1 - 3.3e-10 40.3 0.3 3.3e-10 40.3 0.2 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EJS42953.1 - 0.0013 17.7 0.0 0.0031 16.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EJS42953.1 - 0.044 12.8 0.1 0.085 11.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS42953.1 - 0.093 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRN3 PF05327.6 EJS42954.1 - 6.7e-188 625.3 7.5 8e-188 625.0 5.2 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.5 EJS42954.1 - 3.5 6.5 7.9 5.7 5.9 5.5 1.3 1 0 0 1 1 1 0 BUD22 WD40 PF00400.27 EJS42955.1 - 1.7e-18 65.6 11.9 0.00014 21.5 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Mito_carr PF00153.22 EJS42956.1 - 1.9e-59 197.3 7.4 1.6e-19 69.3 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 EJS42956.1 - 0.051 13.5 0.1 3.5 7.6 0.0 2.8 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Vma12 PF11712.3 EJS42957.1 - 1.4e-37 128.5 0.7 2.1e-37 127.9 0.5 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3169 PF11368.3 EJS42957.1 - 0.0019 17.4 1.8 0.0031 16.7 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) DUF3278 PF11683.3 EJS42957.1 - 0.023 14.6 1.1 0.036 14.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) MscS_TM PF12794.2 EJS42957.1 - 0.023 13.3 0.4 0.023 13.3 0.3 1.6 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 2TM PF13239.1 EJS42957.1 - 0.072 13.1 0.6 0.14 12.2 0.4 1.5 1 0 0 1 1 1 0 2TM domain Complex1_LYR_2 PF13233.1 EJS42957.1 - 0.24 11.9 3.7 0.7 10.3 2.5 1.8 1 1 0 1 1 1 0 Complex1_LYR-like XPG_N PF00752.12 EJS42958.1 - 6.2e-40 135.5 0.0 1.4e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EJS42958.1 - 1.5e-28 98.7 0.0 3.7e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EJS42958.1 - 1.3e-05 25.3 2.1 3.9e-05 23.8 0.0 2.6 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 EJS42958.1 - 0.016 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain HHH_2 PF12826.2 EJS42958.1 - 0.029 14.2 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif CDKN3 PF05706.7 EJS42958.1 - 0.055 12.9 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF4463 PF14703.1 EJS42958.1 - 2.2 8.8 9.1 0.14 12.7 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) BAF1_ABF1 PF04684.8 EJS42959.1 - 1.8e-93 314.0 43.2 7e-54 183.4 20.5 5.5 1 1 3 5 5 5 3 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.10 EJS42959.1 - 0.0002 20.8 0.0 0.00041 19.8 0.0 1.5 1 0 0 1 1 1 1 MuDR family transposase KTI12 PF08433.5 EJS42960.1 - 1.6e-96 322.7 0.0 1.8e-96 322.4 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EJS42960.1 - 3.9e-06 26.7 0.0 8.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EJS42960.1 - 4.5e-06 26.9 0.0 1.4e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EJS42960.1 - 8.4e-05 23.3 0.0 0.0002 22.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EJS42960.1 - 0.0021 17.7 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.5 EJS42960.1 - 0.012 14.8 0.1 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EJS42960.1 - 0.014 15.4 0.1 0.057 13.3 0.0 1.9 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 EJS42960.1 - 0.021 14.9 0.0 0.073 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.13 EJS42960.1 - 0.048 12.7 1.2 0.4 9.7 0.0 2.4 2 1 0 2 2 2 0 6-phosphofructo-2-kinase AAA PF00004.24 EJS42960.1 - 0.057 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EJS42960.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hap4_Hap_bind PF10297.4 EJS42961.1 - 5.7e-08 32.3 6.4 1.6e-07 30.9 4.4 1.8 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Drc1-Sld2 PF11719.3 EJS42962.1 - 4.6e-72 243.4 21.3 1.3e-69 235.3 14.7 2.0 1 1 0 1 1 1 1 DNA replication and checkpoint protein LRAT PF04970.8 EJS42962.1 - 0.039 13.8 2.3 0.049 13.5 0.1 2.1 2 0 0 2 2 2 0 Lecithin retinol acyltransferase Aminotran_1_2 PF00155.16 EJS42963.1 - 4.6e-100 335.1 0.0 5.2e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SIS PF01380.17 EJS42964.1 - 8.6e-64 213.0 0.0 7.1e-32 109.7 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EJS42964.1 - 4.9e-29 101.1 0.0 1.1e-20 73.6 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EJS42964.1 - 7.9e-19 67.9 0.0 1.6e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EJS42964.1 - 1.4e-11 44.1 0.0 2.8e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EJS42964.1 - 2e-09 36.5 0.0 3.5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EJS42964.1 - 0.013 15.2 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 SIS domain Peptidase_M18 PF02127.10 EJS42965.1 - 2.6e-156 520.4 0.0 3.2e-156 520.1 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EJS42965.1 - 0.065 11.9 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Pkinase PF00069.20 EJS42966.1 - 9.5e-72 241.2 0.0 6.3e-71 238.5 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS42966.1 - 3.7e-34 117.9 0.0 1.3e-32 112.9 0.0 2.3 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EJS42966.1 - 0.0036 17.0 0.0 0.0094 15.7 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EJS42966.1 - 0.0036 16.3 0.0 0.0074 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EJS42966.1 - 0.0045 16.5 0.0 0.0045 16.5 0.0 3.2 4 0 0 4 4 4 1 Choline/ethanolamine kinase Peptidase_A22B PF04258.8 EJS42967.1 - 6.7e-83 278.5 12.8 1.1e-82 277.8 8.8 1.3 1 0 0 1 1 1 1 Signal peptide peptidase DUF3815 PF12821.2 EJS42967.1 - 0.021 14.7 0.2 0.021 14.7 0.1 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3815) LrgA PF03788.9 EJS42967.1 - 0.065 12.9 0.2 0.065 12.9 0.2 2.8 3 0 0 3 3 3 0 LrgA family PIR PF00399.14 EJS42969.1 - 1.4e-08 33.7 10.1 1.4e-08 33.7 7.0 3.3 2 1 1 3 3 3 1 Yeast PIR protein repeat EIIBC-GUT_N PF03612.9 EJS42969.1 - 0.031 13.9 1.8 0.037 13.6 1.3 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ATP12 PF07542.6 EJS42969.1 - 0.044 13.7 0.6 0.05 13.5 0.4 1.2 1 0 0 1 1 1 0 ATP12 chaperone protein Mucin PF01456.12 EJS42969.1 - 1.4 8.6 18.6 1.6 8.4 12.9 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein TMEM154 PF15102.1 EJS42969.1 - 6.2 6.5 7.7 7.6 6.2 5.3 1.2 1 0 0 1 1 1 0 TMEM154 protein family Rifin_STEVOR PF02009.11 EJS42969.1 - 6.4 6.3 5.8 6.5 6.3 4.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family PIR PF00399.14 EJS42970.1 - 1.4e-07 30.5 3.3 4.9e-07 28.8 2.3 2.0 1 0 0 1 1 1 1 Yeast PIR protein repeat DUF3846 PF12957.2 EJS42970.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) Macoilin PF09726.4 EJS42970.1 - 8.1 4.5 15.1 8.8 4.4 10.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 EJS42971.1 - 5e-49 167.2 20.0 1e-48 166.2 13.9 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF572) Mut7-C PF01927.11 EJS42971.1 - 0.056 13.4 0.3 0.056 13.4 0.2 2.2 2 1 0 2 2 2 0 Mut7-C RNAse domain DUF4291 PF14124.1 EJS42971.1 - 0.097 12.2 5.2 0.15 11.6 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) Benyvirus_14KDa PF07255.6 EJS42971.1 - 0.098 12.5 0.3 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 Benyvirus 14KDa protein Cytochrom_C552 PF02335.10 EJS42971.1 - 0.44 9.1 7.4 0.23 10.1 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c552 E7 PF00527.13 EJS42971.1 - 0.68 10.1 0.0 0.68 10.1 0.0 2.8 2 1 0 3 3 3 0 E7 protein, Early protein RRN3 PF05327.6 EJS42971.1 - 0.72 7.8 10.7 1 7.3 7.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 V_ATPase_I PF01496.14 EJS42971.1 - 0.76 7.5 9.9 1.2 6.8 6.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Iron_permease PF04120.7 EJS42971.1 - 1.7 8.2 7.9 0.18 11.3 2.4 1.6 2 0 0 2 2 2 0 Low affinity iron permease HSP70 PF00012.15 EJS42971.1 - 8.8 4.0 12.3 13 3.5 8.5 1.2 1 0 0 1 1 1 0 Hsp70 protein CRAL_TRIO PF00650.15 EJS42973.1 - 6.3e-34 116.7 0.3 9.3e-34 116.2 0.2 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EJS42973.1 - 5.4e-13 48.8 0.0 1.6e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EJS42973.1 - 7.8e-05 22.6 0.1 0.00016 21.6 0.1 1.6 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CUE PF02845.11 EJS42974.1 - 7.1e-19 66.9 1.6 2.5e-09 36.4 0.1 3.2 3 0 0 3 3 3 2 CUE domain Smr PF01713.16 EJS42974.1 - 3e-12 46.5 0.0 6.6e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Smr domain CENP-C_C PF11699.3 EJS42975.1 - 2e-31 107.8 1.5 3.9e-31 106.8 1.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 EJS42975.1 - 3e-23 82.9 6.6 3e-23 82.9 4.6 2.7 2 1 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 EJS42975.1 - 0.004 16.6 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AT_hook PF02178.14 EJS42975.1 - 0.094 12.4 5.4 0.29 10.9 3.8 1.9 1 0 0 1 1 1 0 AT hook motif Cyto_heme_lyase PF01265.12 EJS42976.1 - 2.8e-78 263.0 6.4 6.7e-78 261.8 4.5 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase ParBc PF02195.13 EJS42977.1 - 3.6e-22 78.2 0.0 4.5e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Ldh_1_C PF02866.13 EJS42978.1 - 1.5e-52 177.8 0.0 2.4e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EJS42978.1 - 1.5e-43 147.9 0.1 2.4e-43 147.3 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EJS42978.1 - 0.00025 19.8 0.0 0.00034 19.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2737 PF10930.3 EJS42978.1 - 0.1 12.2 0.0 0.42 10.2 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) zf-CHY PF05495.7 EJS42979.1 - 1.6e-16 60.1 12.6 2.5e-16 59.6 8.7 1.3 1 0 0 1 1 1 1 CHY zinc finger zf-RING_4 PF14570.1 EJS42979.1 - 0.0002 20.8 0.4 0.0002 20.8 0.3 3.0 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain Zn_ribbon_recom PF13408.1 EJS42979.1 - 0.00038 20.6 1.0 0.00038 20.6 0.7 2.2 2 1 0 2 2 2 1 Recombinase zinc beta ribbon domain zf-C3HC4_3 PF13920.1 EJS42979.1 - 0.0077 15.8 0.7 0.0077 15.8 0.5 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.7 EJS42979.1 - 0.0085 15.3 3.3 0.0085 15.3 2.3 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.2 EJS42979.1 - 0.016 14.9 6.9 0.23 11.3 4.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 EJS42979.1 - 0.03 13.7 2.5 0.03 13.7 1.7 2.5 2 1 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EJS42979.1 - 0.032 14.1 0.9 0.032 14.1 0.6 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 EJS42979.1 - 0.04 13.5 0.5 12 5.6 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Trm112p PF03966.11 EJS42979.1 - 0.055 13.8 3.7 0.2 12.0 2.4 2.2 1 1 0 1 1 1 0 Trm112p-like protein zf-NADH-PPase PF09297.6 EJS42979.1 - 0.2 11.1 6.7 0.82 9.2 2.7 2.7 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-RING_3 PF14369.1 EJS42979.1 - 0.29 11.1 9.3 0.93 9.5 1.9 2.6 1 1 1 2 2 2 0 zinc-finger PhnA_Zn_Ribbon PF08274.7 EJS42979.1 - 0.5 10.1 10.4 0.69 9.7 0.1 3.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DUF2318 PF10080.4 EJS42979.1 - 0.67 9.7 4.4 0.56 10.0 1.7 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) DUF1272 PF06906.6 EJS42979.1 - 0.99 9.3 9.8 0.63 9.9 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) Tetraspannin PF00335.15 EJS42979.1 - 1.6 7.9 6.6 4.3 6.5 4.6 1.7 1 1 0 1 1 1 0 Tetraspanin family DNA_RNApol_7kD PF03604.8 EJS42979.1 - 2.2 7.8 7.2 9.5 5.7 0.3 3.2 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-trcl PF13451.1 EJS42979.1 - 2.7 7.7 6.5 9.2 5.9 1.8 3.0 2 1 0 2 2 2 0 Probable zinc-binding domain Lar_restr_allev PF14354.1 EJS42979.1 - 3.5 8.0 8.8 0.22 11.8 1.2 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar SURF6 PF04935.7 EJS42980.1 - 2.1e-56 190.5 48.9 2.1e-56 190.5 33.9 3.1 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 EJS42980.1 - 1.3e-18 66.8 3.4 1.3e-18 66.8 2.4 7.1 5 3 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 V-ATPase_C PF03223.10 EJS42981.1 - 1.1e-123 412.7 1.3 1.3e-123 412.6 0.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NUC130_3NT PF08158.7 EJS42981.1 - 0.016 15.4 0.1 8.5 6.7 0.0 2.5 2 0 0 2 2 2 0 NUC130/3NT domain OB_NTP_bind PF07717.11 EJS42982.1 - 8.8e-20 70.6 0.0 1.7e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EJS42982.1 - 6.4e-19 67.8 0.0 1.3e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 EJS42982.1 - 1.9e-09 37.2 0.2 3.6e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS42982.1 - 2.8e-09 36.7 0.0 7.9e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EJS42982.1 - 1.5e-06 28.3 0.1 3.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EJS42982.1 - 8.7e-05 22.1 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EJS42982.1 - 0.0017 18.6 0.2 0.083 13.1 0.1 2.8 2 1 1 3 3 3 1 ABC transporter AAA_14 PF13173.1 EJS42982.1 - 0.0032 17.3 0.1 0.032 14.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EJS42982.1 - 0.0037 16.9 0.0 0.0099 15.5 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EJS42982.1 - 0.0038 16.7 0.5 0.0079 15.7 0.0 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EJS42982.1 - 0.012 15.9 0.1 0.039 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EJS42982.1 - 0.014 14.9 0.6 0.29 10.6 0.0 2.5 1 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EJS42982.1 - 0.016 14.6 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain SRP54 PF00448.17 EJS42982.1 - 0.021 14.2 0.2 0.092 12.1 0.1 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Helicase_RecD PF05127.9 EJS42982.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Helicase DUF2075 PF09848.4 EJS42982.1 - 0.052 12.5 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EJS42982.1 - 0.053 13.0 0.4 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EJS42982.1 - 0.079 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zot PF05707.7 EJS42982.1 - 0.079 12.4 0.0 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) ResIII PF04851.10 EJS42982.1 - 0.094 12.5 0.1 1.5 8.6 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EJS42982.1 - 0.11 12.4 0.1 0.31 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Flavi_DEAD PF07652.9 EJS42982.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain HSP70 PF00012.15 EJS42984.1 - 2.8e-52 177.4 2.1 2.8e-52 177.4 1.4 2.1 2 1 1 3 3 3 1 Hsp70 protein Methyltransf_28 PF02636.12 EJS42985.1 - 3.4e-13 49.5 0.0 4.9e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Elf1 PF05129.8 EJS42986.1 - 2e-31 107.4 2.9 2.7e-31 107.0 2.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like CDC45 PF02724.9 EJS42986.1 - 0.019 13.0 8.8 0.022 12.7 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EJS42986.1 - 0.054 11.4 7.2 0.047 11.6 5.0 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EJS42986.1 - 0.091 12.0 10.8 0.12 11.5 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L37ae PF01780.14 EJS42986.1 - 0.12 12.2 1.3 0.19 11.6 0.9 1.3 1 0 0 1 1 1 0 Ribosomal L37ae protein family BUD22 PF09073.5 EJS42986.1 - 0.26 10.3 12.9 0.32 10.0 8.9 1.2 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.6 EJS42986.1 - 0.3 8.9 5.9 0.33 8.7 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Rsm22 PF09243.5 EJS42987.1 - 2.8e-29 102.0 0.3 7.4e-10 38.3 0.1 4.3 3 1 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 EJS42987.1 - 0.00092 18.9 0.0 0.0023 17.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS42987.1 - 0.02 15.4 0.0 0.071 13.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain SRPRB PF09439.5 EJS42988.1 - 8.2e-68 227.1 0.2 1.4e-67 226.4 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EJS42988.1 - 7.4e-11 41.5 0.0 1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EJS42988.1 - 1.4e-07 31.5 0.0 3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EJS42988.1 - 0.00011 21.4 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EJS42988.1 - 0.00076 18.9 0.1 0.016 14.6 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EJS42988.1 - 0.0011 19.4 0.0 0.0037 17.7 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EJS42988.1 - 0.0014 17.9 0.1 0.0027 16.9 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EJS42988.1 - 0.0081 15.9 4.1 0.67 9.7 2.9 3.2 1 1 0 1 1 1 1 Dynamin family Nop25 PF09805.4 EJS42988.1 - 0.027 14.5 1.1 0.042 13.9 0.8 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) AAA_23 PF13476.1 EJS42988.1 - 0.029 14.7 5.3 0.23 11.7 0.3 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EJS42988.1 - 0.055 13.1 2.4 0.57 9.8 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase DUF2570 PF10828.3 EJS42988.1 - 0.067 12.8 0.3 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) AAA_16 PF13191.1 EJS42988.1 - 0.07 13.1 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EJS42988.1 - 0.08 13.0 0.0 0.78 9.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EJS42988.1 - 0.088 12.7 0.4 0.28 11.1 0.0 1.9 1 1 0 2 2 2 0 AAA domain Mso1_C PF14477.1 EJS42988.1 - 0.19 12.1 0.8 2 8.8 0.0 2.2 2 0 0 2 2 2 0 Membrane-polarising domain of Mso1 His_Phos_1 PF00300.17 EJS42989.1 - 1.3e-43 148.8 0.0 1.6e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Longin PF13774.1 EJS42990.1 - 1e-16 60.2 0.0 1.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EJS42990.1 - 3.5e-15 55.3 1.1 5.7e-15 54.7 0.8 1.3 1 0 0 1 1 1 1 Synaptobrevin UPF0449 PF15136.1 EJS42990.1 - 0.031 14.4 0.5 0.051 13.7 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Tbf5 PF06331.7 EJS42990.1 - 0.085 12.6 0.4 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 tRNA-synt_2b PF00587.20 EJS42991.1 - 2.1e-48 164.1 0.0 3.6e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EJS42991.1 - 2.2e-19 69.1 0.3 3.5e-19 68.5 0.2 1.3 1 0 0 1 1 1 1 Anticodon binding domain Caps_assemb_Wzi PF14052.1 EJS42991.1 - 0.05 12.4 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Capsule assembly protein Wzi PP-binding PF00550.20 EJS42992.1 - 9.6e-13 48.1 0.3 1.3e-12 47.7 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EJS42992.1 - 2.9e-07 30.4 0.9 3.9e-07 30.0 0.6 1.3 1 1 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EJS42992.1 - 0.00023 21.2 0.4 0.00033 20.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Diphthamide_syn PF01866.12 EJS42993.1 - 2.7e-43 148.3 0.0 1.8e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Mo25 PF08569.6 EJS42994.1 - 1.8e-123 411.8 9.8 2.1e-123 411.6 6.8 1.0 1 0 0 1 1 1 1 Mo25-like DUF1436 PF07262.6 EJS42994.1 - 0.001 18.5 0.9 0.0019 17.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1436) YqbF PF14553.1 EJS42994.1 - 0.1 12.3 0.0 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 YqbF, hypothetical protein domain GATA PF00320.22 EJS42995.1 - 7.8e-10 37.9 8.9 2e-09 36.6 6.1 1.8 1 0 0 1 1 1 1 GATA zinc finger RXT2_N PF08595.6 EJS42995.1 - 0.29 10.9 5.6 0.27 11.0 0.3 2.9 3 0 0 3 3 3 0 RXT2-like, N-terminal Acyl_transf_1 PF00698.16 EJS42996.1 - 3.7e-105 351.7 0.0 8e-104 347.3 0.0 3.0 4 0 0 4 4 4 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EJS42996.1 - 1.3e-38 131.1 0.0 2.5e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EJS42996.1 - 4.7e-29 99.9 0.3 1.4e-28 98.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EJS42996.1 - 1.7e-16 60.1 0.0 5.7e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EJS42996.1 - 0.0057 15.8 0.1 0.015 14.5 0.0 1.7 1 0 0 1 1 1 1 Nitronate monooxygenase Lipase_3 PF01764.20 EJS42996.1 - 0.11 12.0 0.4 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Pribosyl_synth PF14572.1 EJS42997.1 - 1.4e-39 135.7 1.1 1.3e-31 109.8 0.1 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EJS42997.1 - 2e-39 133.9 0.0 1e-38 131.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EJS42997.1 - 6.5e-07 29.1 0.2 2.2e-05 24.1 0.1 2.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Zip PF02535.17 EJS42998.1 - 2.7e-23 82.4 21.4 1.1e-21 77.1 14.8 2.8 1 1 0 1 1 1 1 ZIP Zinc transporter GtrA PF04138.9 EJS42998.1 - 1.6 8.6 6.1 0.41 10.6 0.3 2.6 2 1 1 3 3 3 0 GtrA-like protein Virul_fac_BrkB PF03631.10 EJS42998.1 - 6.3 6.0 10.1 0.096 12.0 0.8 2.1 2 1 0 2 2 2 0 Virulence factor BrkB AA_permease PF00324.16 EJS42999.1 - 9.9e-99 330.8 44.0 1.2e-98 330.5 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS42999.1 - 8.1e-33 113.5 48.9 1.1e-32 113.1 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3810 PF12725.2 EJS42999.1 - 0.16 10.8 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Ebp2 PF05890.7 EJS43000.1 - 1.4e-85 286.8 25.9 1.4e-85 286.8 18.0 2.3 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Ribosomal_L14 PF00238.14 EJS43001.1 - 5e-39 132.8 4.0 5.7e-39 132.6 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.20 EJS43002.1 - 1.2e-72 244.2 0.0 1.4e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43002.1 - 4.9e-41 140.5 0.0 6.6e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43002.1 - 0.00024 20.1 0.0 0.0004 19.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EJS43002.1 - 0.052 13.2 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EJS43002.1 - 0.073 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EJS43002.1 - 0.084 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EJS43002.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PigN PF04987.9 EJS43003.1 - 1.5e-136 455.6 45.7 1.9e-136 455.2 31.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EJS43003.1 - 9.7e-15 54.7 1.0 1.9e-10 40.6 0.1 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EJS43003.1 - 1.4e-09 37.5 0.1 2.3e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EJS43003.1 - 0.00025 20.5 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily AAA PF00004.24 EJS43004.1 - 1.8e-50 170.5 0.0 3.2e-43 147.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EJS43004.1 - 1.9e-21 75.8 0.1 5.1e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EJS43004.1 - 7.9e-12 45.5 0.0 5.6e-05 23.2 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 EJS43004.1 - 1.9e-08 34.2 0.0 0.0029 17.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EJS43004.1 - 6.6e-07 29.1 0.5 0.0076 15.9 0.0 3.5 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.1 EJS43004.1 - 2.1e-05 24.6 0.4 0.21 11.6 0.1 3.9 3 2 1 4 4 3 2 AAA domain Arch_ATPase PF01637.13 EJS43004.1 - 2.3e-05 24.1 0.9 0.072 12.7 0.0 4.1 3 1 1 4 4 4 1 Archaeal ATPase RNA_helicase PF00910.17 EJS43004.1 - 8.5e-05 22.6 0.1 1.2 9.3 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_25 PF13481.1 EJS43004.1 - 0.00037 19.9 0.0 1.3 8.3 0.0 3.6 2 2 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EJS43004.1 - 0.00085 19.0 0.0 0.43 10.3 0.0 3.3 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EJS43004.1 - 0.00097 19.0 0.0 0.014 15.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EJS43004.1 - 0.001 19.8 0.5 0.012 16.3 0.0 3.1 4 1 0 4 4 2 1 AAA domain RuvB_N PF05496.7 EJS43004.1 - 0.0011 18.0 0.0 0.0051 15.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EJS43004.1 - 0.0012 18.5 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 EJS43004.1 - 0.0026 17.1 0.0 0.21 10.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EJS43004.1 - 0.0041 16.2 0.0 0.22 10.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EJS43004.1 - 0.0058 16.5 0.0 0.041 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EJS43004.1 - 0.0089 15.5 0.1 1.2 8.6 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EJS43004.1 - 0.027 13.3 0.0 2.1 7.1 0.0 2.8 2 1 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.10 EJS43004.1 - 0.033 14.0 0.1 2 8.2 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 EJS43004.1 - 0.039 13.4 0.0 10 5.5 0.0 3.0 3 1 0 3 3 3 0 Sigma-54 interaction domain Vps4_C PF09336.5 EJS43004.1 - 0.086 12.7 0.2 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 EJS43004.1 - 0.089 12.3 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DHO_dh PF01180.16 EJS43005.1 - 2.5e-97 325.4 0.0 2.8e-97 325.2 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EJS43005.1 - 5e-05 22.3 0.1 0.0019 17.0 0.0 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Polysacc_deac_1 PF01522.16 EJS43005.1 - 0.017 14.7 0.0 0.21 11.1 0.0 2.2 1 1 1 2 2 2 0 Polysaccharide deacetylase NMO PF03060.10 EJS43005.1 - 0.039 13.1 0.1 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Glu_synthase PF01645.12 EJS43005.1 - 0.061 12.2 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase RRM_6 PF14259.1 EJS43006.1 - 5.6e-06 26.2 0.0 8.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EJS43006.1 - 8.2e-06 26.1 2.9 1.9e-05 24.9 2.0 1.7 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.17 EJS43006.1 - 1.1e-05 24.9 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS43006.1 - 0.0058 16.4 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Syja_N PF02383.13 EJS43007.1 - 1.1e-83 280.6 4.4 1.4e-83 280.2 3.1 1.2 1 0 0 1 1 1 1 SacI homology domain IGPS PF00218.16 EJS43008.1 - 3.5e-98 327.7 0.0 4.3e-98 327.4 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 EJS43008.1 - 1.2e-55 187.9 0.0 2.1e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EJS43008.1 - 4.2e-10 39.4 0.0 8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EJS43008.1 - 7.9e-05 22.2 0.1 0.00018 21.1 0.1 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EJS43008.1 - 0.029 13.6 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.9 EJS43008.1 - 0.14 11.0 0.0 0.3 10.0 0.0 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase PAC2 PF09754.4 EJS43009.1 - 9.2e-27 94.3 0.0 1.4e-26 93.6 0.0 1.3 1 1 0 1 1 1 1 PAC2 family FAT PF02259.18 EJS43011.1 - 8.1e-135 449.3 2.3 8.1e-135 449.3 1.6 3.5 4 0 0 4 4 4 1 FAT domain DUF3385 PF11865.3 EJS43011.1 - 5.9e-64 214.8 6.1 8.8e-63 211.0 0.1 4.7 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EJS43011.1 - 6e-62 209.1 0.2 1.3e-61 208.0 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EJS43011.1 - 5.4e-42 141.9 0.7 5.4e-42 141.9 0.5 3.3 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 EJS43011.1 - 2.1e-19 68.6 0.1 5.3e-19 67.3 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 EJS43011.1 - 1.3e-14 54.2 7.8 0.016 15.4 0.0 9.6 7 2 2 9 9 9 3 HEAT repeats HEAT_EZ PF13513.1 EJS43011.1 - 6.3e-11 42.4 0.4 0.012 16.1 0.0 9.1 6 1 2 9 9 9 2 HEAT-like repeat HEAT PF02985.17 EJS43011.1 - 2.4e-07 30.2 2.6 0.046 13.8 0.0 7.7 9 0 0 9 9 9 1 HEAT repeat TPR_19 PF14559.1 EJS43011.1 - 0.0081 16.4 2.0 0.077 13.3 0.0 3.6 5 0 0 5 5 5 1 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.2 EJS43011.1 - 0.026 14.8 2.1 0.95 9.8 0.0 4.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region MFS_1 PF07690.11 EJS43012.1 - 1.7e-31 109.2 24.1 1.7e-31 109.2 16.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 EJS43012.1 - 0.06 13.7 0.5 0.28 11.5 0.0 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pox_A14 PF05767.7 EJS43012.1 - 1.2 9.1 7.7 2.8 7.9 0.6 3.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Glyco_hydro_28 PF00295.12 EJS43013.1 - 1.1e-101 340.0 23.9 1.2e-101 339.9 16.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EJS43013.1 - 0.00027 20.7 35.8 0.023 14.4 24.8 2.7 1 1 0 1 1 1 1 Right handed beta helix region PUF PF00806.14 EJS43014.1 - 3.4e-33 111.2 10.5 0.00026 20.2 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat Cpn60_TCP1 PF00118.19 EJS43015.1 - 2e-137 458.7 6.8 2.3e-137 458.5 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cyclin_N PF00134.18 EJS43016.1 - 1.4e-09 37.5 2.1 2.8e-09 36.5 1.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain SYS1 PF09801.4 EJS43017.1 - 6e-49 165.7 12.8 7.1e-49 165.5 8.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX16 PF14138.1 EJS43018.1 - 3.5e-31 107.1 0.2 5.7e-31 106.5 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Aa_trans PF01490.13 EJS43019.1 - 1.1e-88 297.4 23.0 1.4e-88 297.1 15.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mpp10 PF04006.7 EJS43020.1 - 1.5e-159 532.2 56.1 1.9e-159 531.8 38.9 1.1 1 0 0 1 1 1 1 Mpp10 protein TORC_M PF12885.2 EJS43020.1 - 8.7 6.0 8.4 1.4 8.7 0.4 2.9 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain Adaptin_N PF01602.15 EJS43021.1 - 7.3e-115 384.2 16.8 9e-115 383.9 11.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EJS43021.1 - 2.5e-06 27.6 0.1 0.26 11.5 0.0 3.7 3 1 1 4 4 4 2 HEAT repeats FANCI_S2 PF14676.1 EJS43021.1 - 0.0099 15.7 1.9 0.0099 15.7 1.3 3.2 4 1 0 4 4 4 1 FANCI solenoid 2 Peptidase_M29 PF02073.10 EJS43022.1 - 0.0014 17.5 1.1 0.0016 17.3 0.8 1.0 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) PV-1 PF06637.6 EJS43022.1 - 0.15 10.5 10.2 0.17 10.3 7.1 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DDRGK PF09756.4 EJS43022.1 - 2.5 7.4 16.1 2.9 7.2 11.2 1.0 1 0 0 1 1 1 0 DDRGK domain CAF-1_p150 PF11600.3 EJS43022.1 - 9.3 5.5 20.5 11 5.3 14.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DNA_pol_E_B PF04042.11 EJS43023.1 - 3.2e-54 183.3 0.1 4.3e-54 182.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B EIF_2_alpha PF07541.7 EJS43024.1 - 3.4e-41 139.5 0.7 5.9e-41 138.7 0.1 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EJS43024.1 - 4.6e-14 52.2 0.6 1.2e-13 50.9 0.4 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Mpp10 PF04006.7 EJS43024.1 - 0.0017 16.8 4.3 0.0028 16.1 2.3 1.7 1 1 1 2 2 2 1 Mpp10 protein EXOSC1 PF10447.4 EJS43024.1 - 0.082 12.8 0.2 0.23 11.4 0.1 1.8 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Gp_dh_C PF02800.15 EJS43025.1 - 3.9e-74 247.3 0.1 6.1e-74 246.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EJS43025.1 - 5.8e-59 198.3 0.1 1.1e-58 197.5 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EJS43025.1 - 0.0082 16.0 1.6 0.013 15.3 0.2 2.2 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EJS43025.1 - 0.071 12.2 0.1 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-sulfurylase PF01747.12 EJS43026.1 - 3.9e-88 294.3 0.0 5.1e-88 293.9 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EJS43026.1 - 7.1e-49 165.2 0.0 1.2e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain SPC12 PF06645.8 EJS43027.1 - 8.7e-25 86.3 0.3 1.1e-24 86.0 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Mannosyl_trans PF05007.8 EJS43028.1 - 3.7e-102 341.4 21.4 3.7e-102 341.4 14.8 1.9 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EJS43028.1 - 1.1e-16 60.7 10.5 1.1e-16 60.7 7.3 1.9 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EJS43028.1 - 2.5e-08 33.7 3.0 2.5e-08 33.7 2.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) PMT_2 PF13231.1 EJS43028.1 - 4.8e-05 23.3 11.0 4.8e-05 23.3 7.6 3.1 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase ILVD_EDD PF00920.16 EJS43029.1 - 1.9e-205 683.2 0.1 2.2e-205 683.0 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Rotamase PF00639.16 EJS43030.1 - 2.5e-27 95.4 0.0 3.4e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EJS43030.1 - 2.3e-21 76.2 0.0 3.2e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EJS43030.1 - 4.7e-08 33.7 0.0 7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EJS43030.1 - 2.4e-07 30.4 2.1 4e-07 29.7 1.5 1.4 1 0 0 1 1 1 1 WW domain Acyl_CoA_thio PF02551.10 EJS43031.1 - 7.7e-60 200.2 5.1 5.1e-45 152.3 1.4 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 EJS43031.1 - 1.7e-22 80.4 0.0 2.2e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 3-HAO PF06052.7 EJS43032.1 - 8.7e-71 236.2 0.1 1e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EJS43032.1 - 1.7e-05 24.1 0.0 3.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EJS43032.1 - 0.021 14.2 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Cupin DUF2296 PF10058.4 EJS43032.1 - 0.041 13.6 1.2 0.6 9.8 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) AraC_binding PF02311.14 EJS43032.1 - 0.082 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain DZR PF12773.2 EJS43032.1 - 0.17 11.7 1.7 0.96 9.3 1.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon Pro_isomerase PF00160.16 EJS43033.1 - 7.6e-42 143.1 0.0 1.2e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EJS43033.1 - 1.1e-13 50.6 4.7 2.9e-06 26.8 0.1 2.9 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EJS43033.1 - 1.8e-10 39.8 6.8 4.5e-06 26.1 0.8 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EJS43033.1 - 7.4e-08 31.6 7.6 8e-07 28.4 1.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EJS43033.1 - 5.8e-06 26.1 0.9 0.0018 18.1 0.9 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EJS43033.1 - 0.00031 20.3 8.7 0.038 13.7 0.5 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EJS43033.1 - 0.0028 18.3 0.2 0.01 16.5 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EJS43033.1 - 0.015 15.4 3.4 0.17 12.0 0.4 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EJS43033.1 - 0.082 12.7 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Pet191_N PF10203.4 EJS43034.1 - 3.7e-26 90.9 3.1 5.4e-26 90.4 2.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EJS43034.1 - 0.011 15.4 1.1 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EJS43034.1 - 0.33 10.9 4.9 0.65 9.9 0.2 2.8 3 0 0 3 3 3 0 CHCH domain HECT PF00632.20 EJS43035.1 - 5.6e-81 272.1 5.5 1.2e-80 271.0 3.8 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Voltage_CLC PF00654.15 EJS43036.1 - 1.5e-79 267.6 23.3 1.5e-79 267.6 16.2 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EJS43036.1 - 1.3e-12 47.2 0.0 7e-05 22.5 0.0 2.9 2 0 0 2 2 2 2 CBS domain Urb2 PF10441.4 EJS43037.1 - 2e-63 213.9 3.9 2e-63 213.9 2.7 2.1 2 0 0 2 2 2 1 Urb2/Npa2 family Nucleopor_Nup85 PF07575.8 EJS43038.1 - 4.3e-174 579.8 0.9 5e-174 579.6 0.6 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin CDC27 PF09507.5 EJS43039.1 - 0.00016 21.0 36.9 0.00035 19.9 23.7 2.5 2 1 0 2 2 2 1 DNA polymerase subunit Cdc27 RRP7 PF12923.2 EJS43039.1 - 0.0017 18.3 0.9 0.0017 18.3 0.6 2.5 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Vps55 PF04133.9 EJS43040.1 - 3.8e-44 149.2 6.4 4.6e-44 149.0 4.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2085 PF09858.4 EJS43040.1 - 0.005 16.8 0.2 0.005 16.8 0.1 1.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2085) 5TM-5TMR_LYT PF07694.7 EJS43040.1 - 0.061 12.6 3.2 0.13 11.6 1.7 1.7 1 1 1 2 2 2 0 5TMR of 5TMR-LYT DUF998 PF06197.8 EJS43040.1 - 0.72 9.1 5.1 0.73 9.1 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF998) eIF-5a PF01287.15 EJS43041.1 - 4.7e-28 96.9 0.4 7.3e-28 96.3 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EJS43041.1 - 0.00028 20.4 0.5 0.00052 19.6 0.4 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EJS43041.1 - 0.0057 16.4 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain TcdB_toxin_midN PF12256.3 EJS43041.1 - 0.073 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region Cytochrom_C PF00034.16 EJS43042.1 - 3.2e-10 40.6 0.1 5.5e-10 39.9 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EJS43042.1 - 1.3e-07 31.6 1.7 1.6e-06 28.1 1.2 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EJS43042.1 - 0.013 14.9 0.5 0.052 13.0 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 EJS43042.1 - 0.098 12.3 0.1 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Cytochrome C1 family NAD_kinase PF01513.16 EJS43043.1 - 5.1e-82 274.8 0.0 7.2e-82 274.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EJS43043.1 - 0.07 12.5 0.0 0.44 9.9 0.0 2.3 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain DUF3203 PF11462.3 EJS43043.1 - 0.083 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) Isy1 PF06246.7 EJS43044.1 - 3.3e-43 147.9 18.0 2e-41 142.1 12.5 2.0 1 1 0 1 1 1 1 Isy1-like splicing family FAD_binding_2 PF00890.19 EJS43045.1 - 2.3e-71 240.8 0.0 2.6e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EJS43045.1 - 1.6e-06 28.1 0.1 0.0015 18.4 0.0 3.4 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EJS43045.1 - 1.1e-05 25.4 0.1 5.2e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EJS43045.1 - 2.4e-05 24.5 0.0 0.00019 21.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EJS43045.1 - 0.00012 20.7 0.2 0.32 9.4 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 EJS43045.1 - 0.00012 21.2 0.4 0.011 14.8 0.0 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EJS43045.1 - 0.00015 20.7 0.0 0.004 16.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EJS43045.1 - 0.0092 15.7 0.0 0.09 12.5 0.0 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EJS43045.1 - 0.016 14.1 0.0 0.25 10.2 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EJS43045.1 - 0.072 12.1 0.2 0.14 11.2 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.14 EJS43045.1 - 0.15 11.1 0.9 9.6 5.2 0.0 2.9 3 0 0 3 3 3 0 GMC oxidoreductase LRR_6 PF13516.1 EJS43046.1 - 0.031 14.3 13.6 19 5.7 0.1 7.5 8 0 0 8 8 8 0 Leucine Rich repeat Nucleoplasmin PF03066.10 EJS43047.1 - 2.4 7.6 14.0 0.078 12.4 2.1 2.4 2 0 0 2 2 2 0 Nucleoplasmin Brevenin PF03032.10 EJS43047.1 - 3.7 7.4 16.1 10 6.0 11.1 1.8 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family zf-HIT PF04438.11 EJS43049.1 - 1.2e-12 47.2 11.4 2.6e-12 46.1 7.9 1.6 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.6 EJS43049.1 - 0.01 15.3 0.0 0.027 14.0 0.0 1.8 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-Mss51 PF13824.1 EJS43049.1 - 0.01 15.6 4.6 0.056 13.3 3.7 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 CDC14 PF08045.6 EJS43049.1 - 0.016 14.3 0.6 0.022 13.8 0.4 1.1 1 0 0 1 1 1 0 Cell division control protein 14, SIN component zf-MYND PF01753.13 EJS43049.1 - 0.88 9.5 13.8 0.14 12.0 6.9 1.7 2 0 0 2 2 2 0 MYND finger Shisa PF13908.1 EJS43049.1 - 6.4 6.9 9.0 10 6.2 6.0 1.5 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Clat_adaptor_s PF01217.15 EJS43050.1 - 3e-57 192.3 1.5 3.4e-57 192.1 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.20 EJS43051.1 - 1.6e-40 138.9 0.0 2.5e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43051.1 - 2.1e-14 53.2 0.0 3.5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EJS43051.1 - 0.0017 17.4 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EJS43051.1 - 0.019 13.9 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like LicD PF04991.8 EJS43052.1 - 7.2e-50 169.9 5.1 7.2e-50 169.9 3.5 3.0 3 0 0 3 3 3 1 LicD family Lipase_chap PF03280.9 EJS43052.1 - 0.01 15.3 0.3 0.19 11.2 0.0 2.4 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein TFIIS_C PF01096.13 EJS43053.1 - 2.5e-17 62.2 1.7 2.5e-17 62.2 1.2 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EJS43053.1 - 4.2e-16 58.3 9.2 5.6e-14 51.5 0.3 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EJS43053.1 - 6.5e-05 23.1 5.4 0.0024 18.1 0.2 2.6 2 1 0 2 2 2 1 Restriction alleviation protein Lar DZR PF12773.2 EJS43053.1 - 0.00056 19.6 7.0 0.39 10.5 0.1 2.9 2 1 0 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.1 EJS43053.1 - 0.0024 17.2 14.6 0.076 12.5 0.2 4.2 3 1 0 4 4 4 1 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EJS43053.1 - 0.0041 16.4 6.8 0.11 11.8 2.2 2.9 2 1 0 2 2 2 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EJS43053.1 - 0.0053 15.9 9.4 1.6 8.0 0.1 4.2 4 0 0 4 4 4 1 zinc-ribbon domain RRN7 PF11781.3 EJS43053.1 - 0.0066 15.9 5.8 4.3 6.9 0.3 3.4 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Terminase_GpA PF05876.7 EJS43053.1 - 0.012 14.0 1.5 0.016 13.5 0.3 1.6 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) Zn_Tnp_IS1595 PF12760.2 EJS43053.1 - 0.017 14.9 0.4 0.017 14.9 0.3 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 EJS43053.1 - 0.017 14.7 7.3 5.9 6.6 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EJS43053.1 - 0.021 14.4 7.6 5.8 6.5 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Rubredoxin PF00301.15 EJS43053.1 - 0.021 14.6 4.6 9.9 6.1 0.2 3.3 3 0 0 3 3 3 0 Rubredoxin Stc1 PF12898.2 EJS43053.1 - 0.026 14.5 3.9 0.086 12.9 0.1 2.2 1 1 1 2 2 2 0 Stc1 domain DUF2072 PF09845.4 EJS43053.1 - 0.029 14.2 6.1 0.067 13.1 0.0 3.1 1 1 0 3 3 3 0 Zn-ribbon containing protein (DUF2072) C1_1 PF00130.17 EJS43053.1 - 0.036 13.7 2.1 2.7 7.7 0.1 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.1 EJS43053.1 - 0.036 14.3 4.0 0.37 11.1 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain DUF2387 PF09526.5 EJS43053.1 - 0.054 13.4 0.2 0.054 13.4 0.1 2.5 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) zf-DNA_Pol PF08996.5 EJS43053.1 - 0.065 12.5 5.0 0.14 11.5 0.7 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger tRNA-synt_1f PF01921.13 EJS43053.1 - 0.12 10.9 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) Ribosomal_L32p PF01783.18 EJS43053.1 - 0.16 12.1 2.0 28 5.0 0.1 3.2 3 0 0 3 3 3 0 Ribosomal L32p protein family Nop10p PF04135.7 EJS43053.1 - 0.18 11.5 1.1 0.37 10.5 0.1 2.0 2 0 0 2 2 1 0 Nucleolar RNA-binding protein, Nop10p family Baculo_LEF5_C PF11792.3 EJS43053.1 - 0.25 10.7 6.3 0.072 12.4 0.6 2.7 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-ISL3 PF14690.1 EJS43053.1 - 0.25 11.4 1.9 4.4 7.4 0.1 3.0 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Prok-RING_1 PF14446.1 EJS43053.1 - 0.27 11.0 8.0 5.5 6.8 0.7 3.4 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 Ogr_Delta PF04606.7 EJS43053.1 - 0.28 10.8 7.9 0.066 12.8 2.0 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 EJS43053.1 - 0.3 11.0 12.1 4.1 7.4 0.1 3.6 3 1 0 3 3 3 0 Zinc ribbon domain Elf1 PF05129.8 EJS43053.1 - 0.37 10.5 4.9 0.34 10.6 0.6 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like ArfGap PF01412.13 EJS43053.1 - 0.46 10.2 3.3 5.3 6.8 0.1 2.2 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf zf-MYND PF01753.13 EJS43053.1 - 0.5 10.2 4.4 8.7 6.3 0.3 2.5 2 1 0 2 2 2 0 MYND finger zinc-ribbons_6 PF07191.7 EJS43053.1 - 0.51 10.1 6.9 2.6 7.9 0.2 2.8 2 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_6 PF14599.1 EJS43053.1 - 0.52 10.1 2.7 2.3 8.0 0.1 2.6 3 0 0 3 3 3 0 Zinc-ribbon HypA PF01155.14 EJS43053.1 - 0.58 9.8 7.5 6.6 6.4 1.7 3.0 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family CpXC PF14353.1 EJS43053.1 - 0.64 9.9 7.6 1.3 8.9 0.0 2.9 1 1 1 3 3 3 0 CpXC protein OrfB_Zn_ribbon PF07282.6 EJS43053.1 - 0.64 9.7 6.7 9.4 5.9 1.5 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-CHY PF05495.7 EJS43053.1 - 1.2 9.3 5.7 7.5 6.7 0.1 2.6 2 1 0 2 2 2 0 CHY zinc finger zf-C4_Topoisom PF01396.14 EJS43053.1 - 1.3 8.5 7.6 0.47 9.9 1.6 2.8 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Nudix_N_2 PF14803.1 EJS43053.1 - 1.4 8.6 11.9 36 4.1 0.0 4.0 3 1 0 3 3 3 0 Nudix N-terminal zf-TFIIB PF13453.1 EJS43053.1 - 2 7.6 6.8 0.44 9.7 0.6 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-AN1 PF01428.11 EJS43053.1 - 2.2 8.2 8.4 32 4.4 0.1 3.4 3 1 0 3 3 3 0 AN1-like Zinc finger GATA PF00320.22 EJS43053.1 - 2.4 7.5 8.7 0.52 9.6 1.2 2.8 3 0 0 3 3 3 0 GATA zinc finger Ribosomal_S27e PF01667.12 EJS43053.1 - 3.8 7.1 9.0 24 4.5 0.0 3.8 3 1 0 3 3 3 0 Ribosomal protein S27 zf-C3HC4_4 PF15227.1 EJS43053.1 - 4 7.4 6.5 11 5.9 0.7 3.1 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EJS43053.1 - 4 7.1 7.7 5.4 6.7 0.1 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.1 EJS43053.1 - 4.2 7.9 7.8 27 5.4 1.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger IBR PF01485.16 EJS43053.1 - 5.7 6.8 11.8 58 3.6 1.4 3.1 1 1 1 2 2 2 0 IBR domain NOB1_Zn_bind PF08772.6 EJS43053.1 - 6.9 6.5 8.6 9.5 6.1 1.4 3.5 3 1 1 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like Cpn60_TCP1 PF00118.19 EJS43054.1 - 8.5e-141 469.8 3.2 9.8e-141 469.6 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Actin PF00022.14 EJS43055.1 - 2.2e-91 306.2 0.0 5.6e-91 304.8 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EJS43055.1 - 3.7e-05 22.4 0.0 0.011 14.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein SecG PF03840.9 EJS43055.1 - 1.4 8.7 4.0 3.2 7.5 2.7 1.6 1 0 0 1 1 1 0 Preprotein translocase SecG subunit FAT PF02259.18 EJS43056.1 - 1.3e-131 438.8 1.1 2.7e-131 437.7 0.2 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EJS43056.1 - 9.6e-62 208.5 0.2 2.3e-61 207.2 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EJS43056.1 - 7.6e-60 201.4 2.0 7.6e-60 201.4 1.4 5.0 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EJS43056.1 - 1.6e-40 137.2 1.0 1.6e-40 137.2 0.7 3.2 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EJS43056.1 - 2.2e-20 72.7 2.9 0.0012 19.1 0.0 9.0 6 2 4 10 10 10 7 HEAT repeats FATC PF02260.15 EJS43056.1 - 1e-17 63.2 1.8 1.2e-17 63.0 0.1 2.1 2 0 0 2 2 2 1 FATC domain HEAT_EZ PF13513.1 EJS43056.1 - 1.9e-11 44.0 2.7 0.00047 20.5 0.0 9.6 11 1 2 13 13 13 2 HEAT-like repeat HEAT PF02985.17 EJS43056.1 - 3.8e-10 38.9 5.4 0.012 15.6 0.0 8.3 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EJS43056.1 - 9.6e-05 22.7 5.7 0.24 11.8 0.0 5.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HrpB1_HrpK PF09613.5 EJS43056.1 - 0.00075 19.0 0.0 0.14 11.6 0.0 2.9 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) Rep_fac_C PF08542.6 EJS43057.1 - 2.8e-16 59.2 0.0 5.3e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EJS43057.1 - 5.8e-16 58.8 0.0 1.3e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EJS43057.1 - 7.8e-14 51.6 0.0 3.3e-13 49.6 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EJS43057.1 - 4.1e-09 35.6 0.1 2.6e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EJS43057.1 - 2.6e-06 27.6 0.0 2.3e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EJS43057.1 - 3.8e-06 26.1 0.0 7.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EJS43057.1 - 8.9e-06 25.4 0.0 1.5e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EJS43057.1 - 3e-05 23.9 0.0 0.00027 20.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EJS43057.1 - 9.1e-05 22.1 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EJS43057.1 - 9.6e-05 22.4 0.0 0.0018 18.2 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EJS43057.1 - 0.00031 19.9 0.0 0.0075 15.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EJS43057.1 - 0.0022 16.9 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EJS43057.1 - 0.0032 17.0 0.6 0.0094 15.5 0.4 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EJS43057.1 - 0.0041 16.7 0.0 0.0092 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EJS43057.1 - 0.0089 16.8 0.0 0.021 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EJS43057.1 - 0.012 15.4 0.3 0.058 13.2 0.0 2.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EJS43057.1 - 0.013 15.8 0.1 0.028 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.3 EJS43057.1 - 0.014 15.1 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III DUF2075 PF09848.4 EJS43057.1 - 0.016 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF4441 PF14536.1 EJS43057.1 - 0.026 14.5 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) SNF2_N PF00176.18 EJS43057.1 - 0.028 13.2 0.0 1.1 7.9 0.0 2.2 1 1 0 2 2 2 0 SNF2 family N-terminal domain TIP49 PF06068.8 EJS43057.1 - 0.038 12.7 0.1 0.14 10.8 0.0 1.9 3 0 0 3 3 3 0 TIP49 C-terminus AAA_5 PF07728.9 EJS43057.1 - 0.039 13.6 0.1 0.35 10.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EJS43057.1 - 0.041 14.1 0.2 0.21 11.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain Latrotoxin_C PF15658.1 EJS43057.1 - 0.043 13.6 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 Latrotoxin C-terminal domain AAA_3 PF07726.6 EJS43057.1 - 0.058 12.9 0.0 0.47 10.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EJS43057.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EJS43057.1 - 0.1 12.0 0.1 0.38 10.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EJS43057.1 - 0.13 11.7 0.1 0.32 10.4 0.0 1.6 1 1 0 1 1 1 0 FtsK/SpoIIIE family Ham1p_like PF01725.11 EJS43058.1 - 1.5e-51 174.4 0.1 1.7e-51 174.2 0.1 1.0 1 0 0 1 1 1 1 Ham1 family CM2 PF03021.9 EJS43058.1 - 0.13 11.7 0.0 5.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Influenza C virus M2 protein ATP_bind_1 PF03029.12 EJS43059.1 - 1.2e-85 286.8 0.1 1.8e-85 286.2 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EJS43059.1 - 6.9e-07 28.8 0.3 1.4e-05 24.6 0.2 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 EJS43059.1 - 3.6e-05 23.2 0.0 7.6e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EJS43059.1 - 4e-05 24.4 0.9 0.0002 22.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EJS43059.1 - 6.1e-05 23.1 0.0 0.00021 21.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EJS43059.1 - 8.9e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EJS43059.1 - 0.00023 20.6 0.0 0.027 13.9 0.0 2.8 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EJS43059.1 - 0.00041 20.0 0.0 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 EJS43059.1 - 0.0005 19.5 0.1 0.0022 17.5 0.1 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_24 PF13479.1 EJS43059.1 - 0.00064 19.3 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EJS43059.1 - 0.0012 18.8 0.0 0.0034 17.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EJS43059.1 - 0.0023 17.2 0.0 0.053 12.7 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 EJS43059.1 - 0.0029 16.4 0.0 0.22 10.2 0.0 2.3 2 0 0 2 2 2 1 ArgK protein KTI12 PF08433.5 EJS43059.1 - 0.003 16.8 0.7 0.096 11.8 0.0 2.2 2 0 0 2 2 2 1 Chromatin associated protein KTI12 SRP54 PF00448.17 EJS43059.1 - 0.0055 16.1 0.0 0.03 13.7 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 EJS43059.1 - 0.006 16.8 1.1 0.017 15.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EJS43059.1 - 0.0077 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Arf PF00025.16 EJS43059.1 - 0.0096 15.1 0.0 0.63 9.2 0.0 3.0 3 1 1 4 4 4 1 ADP-ribosylation factor family SRPRB PF09439.5 EJS43059.1 - 0.01 15.0 0.2 0.78 8.9 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit cobW PF02492.14 EJS43059.1 - 0.015 14.7 0.1 0.23 10.8 0.1 2.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.13 EJS43059.1 - 0.022 14.2 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 EJS43059.1 - 0.028 14.9 0.1 1.5 9.2 0.1 2.6 1 1 0 1 1 1 0 Miro-like protein MobB PF03205.9 EJS43059.1 - 0.029 14.0 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EJS43059.1 - 0.031 13.8 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EJS43059.1 - 0.065 12.4 0.0 1 8.5 0.0 2.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Glyco_tranf_2_3 PF13641.1 EJS43059.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 NB-ARC PF00931.17 EJS43059.1 - 0.14 10.9 1.4 0.26 10.1 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain Gly_transf_sug PF04488.10 EJS43060.1 - 3.3e-16 59.5 0.0 1.4e-15 57.5 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3450 PF11932.3 EJS43060.1 - 0.0047 16.2 1.0 0.0063 15.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) IncA PF04156.9 EJS43060.1 - 0.0054 16.3 3.8 0.009 15.6 2.7 1.3 1 0 0 1 1 1 1 IncA protein UPF0118 PF01594.11 EJS43060.1 - 0.0083 15.1 0.9 0.014 14.4 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF20 Prominin PF05478.6 EJS43060.1 - 0.14 9.6 1.2 0.21 9.0 0.9 1.3 1 0 0 1 1 1 0 Prominin Snapin_Pallidin PF14712.1 EJS43060.1 - 2.1 8.7 8.2 4.8 7.5 5.7 1.6 1 0 0 1 1 1 0 Snapin/Pallidin Septin PF00735.13 EJS43061.1 - 1.1e-110 369.1 0.1 1.8e-110 368.4 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EJS43061.1 - 2.4e-08 33.9 0.0 6.2e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EJS43061.1 - 3.2e-05 23.8 8.4 0.00039 20.2 0.3 3.0 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.22 EJS43061.1 - 4.6e-05 23.7 0.9 0.00013 22.2 0.0 2.1 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EJS43061.1 - 5.1e-05 22.5 1.3 0.00029 20.0 0.9 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EJS43061.1 - 5.7e-05 22.3 0.1 5.7e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 EJS43061.1 - 0.0018 18.7 0.1 0.0055 17.1 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 EJS43061.1 - 0.0022 16.8 0.1 0.0041 15.9 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_10 PF12846.2 EJS43061.1 - 0.0032 16.9 0.0 0.0058 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 EJS43061.1 - 0.01 16.6 1.1 0.036 14.8 0.0 2.5 3 1 0 3 3 3 0 AAA domain MobB PF03205.9 EJS43061.1 - 0.018 14.7 0.1 0.045 13.4 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EJS43061.1 - 0.028 13.8 0.5 0.51 9.7 0.2 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EJS43061.1 - 0.038 13.5 0.1 0.094 12.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EJS43061.1 - 0.059 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EJS43061.1 - 0.064 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family FeoB_N PF02421.13 EJS43061.1 - 0.078 12.2 2.3 0.36 10.1 0.3 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EJS43061.1 - 0.13 11.7 2.3 1.5 8.3 0.2 2.5 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EJS43061.1 - 0.29 11.4 13.4 0.14 12.4 2.8 2.7 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 EJS43062.1 - 6.6e-47 157.1 7.9 6e-19 67.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AIM24 PF01987.12 EJS43063.1 - 1e-07 31.6 0.0 4.5e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 NuA4 PF09340.5 EJS43064.1 - 8.4e-20 70.1 10.2 6.4e-18 64.1 7.1 2.1 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 CENP-Q PF13094.1 EJS43064.1 - 0.077 13.0 1.7 0.11 12.5 1.0 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin_1 PF12718.2 EJS43065.1 - 0.00068 19.5 6.1 0.00068 19.5 4.2 2.1 2 0 0 2 2 2 1 Tropomyosin like Occludin_ELL PF07303.8 EJS43065.1 - 2.1 9.1 12.2 0.3 11.8 2.8 2.4 2 0 0 2 2 2 0 Occludin homology domain DUF327 PF03885.8 EJS43065.1 - 2.5 7.9 12.3 1.1 9.0 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF327) DUF2203 PF09969.4 EJS43065.1 - 2.5 8.3 4.9 1.5 9.0 0.7 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.14 EJS43065.1 - 5.5 4.7 6.4 7.4 4.2 4.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PCI PF01399.22 EJS43066.1 - 5.6e-12 45.8 0.1 1.4e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 PCI domain Tmemb_14 PF03647.8 EJS43067.1 - 2e-24 85.7 7.4 2.3e-24 85.6 5.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C BIV_Env PF05858.7 EJS43067.1 - 0.11 10.3 0.0 0.12 10.3 0.0 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) G-gamma PF00631.17 EJS43068.1 - 3e-27 94.1 0.3 5.6e-27 93.2 0.2 1.5 1 1 0 1 1 1 1 GGL domain FYVE_2 PF02318.11 EJS43068.1 - 0.07 13.0 0.2 0.07 13.0 0.1 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger TPR_2 PF07719.12 EJS43069.1 - 3.9e-07 29.4 1.6 0.00051 19.7 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EJS43069.1 - 0.0001 21.8 0.8 0.0061 16.1 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EJS43069.1 - 0.00057 20.4 0.2 0.041 14.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EJS43069.1 - 0.0006 19.4 1.4 0.017 14.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EJS43069.1 - 0.00066 19.9 1.9 1.5 9.4 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EJS43069.1 - 0.0022 18.4 0.0 5.8 7.8 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EJS43069.1 - 0.0023 17.4 0.4 0.12 12.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EJS43069.1 - 0.0052 16.6 0.5 0.71 9.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EJS43069.1 - 0.0072 16.1 0.0 0.041 13.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EJS43069.1 - 0.026 14.2 0.0 8.2 6.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EJS43069.1 - 0.031 14.5 0.1 2 8.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.2 EJS43070.1 - 2.3e-05 24.0 0.3 5.5e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EJS43070.1 - 0.0011 18.6 0.1 0.0037 16.8 0.1 2.1 1 0 0 1 1 1 1 F-box domain PUF PF00806.14 EJS43071.1 - 5.7e-33 110.5 0.2 1.9e-06 27.0 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EJS43071.1 - 1.4e-07 30.9 0.0 4.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS43071.1 - 6.9e-07 29.0 0.0 1.9e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS43071.1 - 0.00023 21.0 0.0 0.00062 19.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 EJS43073.1 - 6.9e-75 246.8 1.1 5.1e-24 83.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cas_GSU0053 PF09617.5 EJS43073.1 - 0.072 12.8 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Aldo_ket_red PF00248.16 EJS43074.1 - 1.1e-46 158.9 0.0 1.3e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RTP PF02334.11 EJS43074.1 - 0.063 13.2 0.1 2.4 8.1 0.0 2.2 1 1 1 2 2 2 0 Replication terminator protein Peptidase_C12 PF01088.16 EJS43075.1 - 5.1e-48 163.0 0.0 6.1e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Sod_Fe_C PF02777.13 EJS43076.1 - 8.1e-12 44.9 2.0 3.6e-06 26.7 0.7 2.8 1 1 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Pik1 PF11522.3 EJS43076.1 - 0.0036 17.0 0.8 0.0096 15.6 0.2 1.9 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 ESCRT-II PF05871.7 EJS43077.1 - 1.8e-48 163.9 1.4 2.3e-48 163.6 1.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Sod_Cu PF00080.15 EJS43078.1 - 5.5e-46 156.2 1.1 6.6e-46 155.9 0.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PfkB PF00294.19 EJS43079.1 - 2.1e-77 260.1 1.3 2.4e-77 260.0 0.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EJS43079.1 - 9.8e-07 28.2 0.0 1.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Na_Ca_ex PF01699.19 EJS43080.1 - 1.3e-61 206.3 30.6 3e-40 137.0 5.5 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein CPSase_L_D2 PF02786.12 EJS43081.1 - 3.4e-108 359.7 0.0 1.6e-82 275.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EJS43081.1 - 1.2e-37 128.4 1.6 1.6e-37 128.0 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EJS43081.1 - 5.6e-37 127.2 0.4 5e-21 75.2 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 EJS43081.1 - 1.2e-33 115.4 0.0 1.2e-16 60.8 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EJS43081.1 - 1.6e-23 83.0 0.0 1.5e-10 40.3 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EJS43081.1 - 2.3e-17 62.8 0.0 7.7e-08 31.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EJS43081.1 - 2.1e-14 53.3 0.3 1.5e-06 27.7 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EJS43081.1 - 6.7e-06 25.7 0.1 0.0079 15.6 0.1 2.8 2 0 0 2 2 2 2 RimK-like ATP-grasp domain MGS PF02142.17 EJS43081.1 - 4.2e-05 23.3 0.1 0.00019 21.2 0.0 2.2 2 0 0 2 2 1 1 MGS-like domain GARS_A PF01071.14 EJS43081.1 - 0.0016 18.0 0.1 0.94 8.9 0.0 2.7 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EJS43081.1 - 0.012 14.8 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Epimerase PF01370.16 EJS43081.1 - 0.043 13.2 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Myotub-related PF06602.9 EJS43082.1 - 3e-144 480.1 1.3 3.8e-144 479.8 0.9 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 EJS43082.1 - 0.0016 17.8 0.0 0.0039 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GRAM PF02893.15 EJS43082.1 - 0.0073 15.8 0.0 0.025 14.0 0.0 1.9 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.1 EJS43082.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 EJS43082.1 - 0.022 14.3 0.1 0.087 12.4 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain CMD PF02627.15 EJS43083.1 - 9.6e-07 28.5 0.0 5.7e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Nnf1 PF03980.9 EJS43084.1 - 1.5e-30 105.3 9.5 2.9e-30 104.4 6.6 1.5 1 0 0 1 1 1 1 Nnf1 Ta0938 PF11494.3 EJS43084.1 - 0.052 13.6 0.2 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 Ta0938 Prominin PF05478.6 EJS43084.1 - 0.071 10.6 3.2 0.11 9.9 2.2 1.4 1 1 0 1 1 1 0 Prominin V-SNARE PF05008.10 EJS43084.1 - 0.17 12.0 8.2 0.35 11.0 1.3 2.8 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus V_ATPase_I PF01496.14 EJS43084.1 - 0.18 9.6 5.3 0.2 9.4 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 EJS43084.1 - 0.38 10.5 3.5 5.8 6.6 0.2 2.3 2 0 0 2 2 2 0 Laminin Domain II Trns_repr_metal PF02583.12 EJS43084.1 - 0.75 10.0 4.6 25 5.1 0.4 3.2 1 1 1 3 3 3 0 Metal-sensitive transcriptional repressor Spectrin PF00435.16 EJS43084.1 - 1.1 9.5 10.6 0.79 10.0 4.9 2.3 1 1 1 2 2 2 0 Spectrin repeat PFEMP PF03011.10 EJS43084.1 - 1.2 9.4 8.1 0.18 12.1 1.9 1.9 1 1 1 2 2 2 0 PFEMP DBL domain Kinetocho_Slk19 PF12709.2 EJS43084.1 - 1.7 8.7 8.5 0.099 12.7 1.1 2.4 3 0 0 3 3 2 0 Central kinetochore-associated DUF1664 PF07889.7 EJS43084.1 - 1.9 8.3 5.7 4.2 7.1 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4375 PF14300.1 EJS43084.1 - 2 8.3 10.1 5.2 7.0 1.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4375) PNPase PF03726.9 EJS43084.1 - 3.2 8.0 10.7 1.8 8.8 2.5 2.4 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Atg14 PF10186.4 EJS43084.1 - 3.9 6.3 9.9 14 4.5 6.9 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Elongin_A PF06881.6 EJS43084.1 - 7.5 6.9 9.6 0.7 10.2 1.5 2.7 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Ribosomal_S7 PF00177.16 EJS43085.1 - 2.2e-31 108.4 0.3 3.3e-31 107.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e TRAM_LAG1_CLN8 PF03798.11 EJS43086.1 - 1e-30 106.8 20.5 1e-30 106.8 14.2 1.4 2 0 0 2 2 2 1 TLC domain Peptidase_M48 PF01435.13 EJS43087.1 - 2.4e-51 174.5 0.0 3.3e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EJS43087.1 - 0.0022 17.0 0.2 0.0047 15.9 0.1 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2268 PF10026.4 EJS43087.1 - 0.0047 16.3 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) JmjC PF02373.17 EJS43088.1 - 5.5e-40 136.1 0.4 1.3e-39 134.9 0.3 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EJS43088.1 - 2.5e-13 49.2 0.2 6.2e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 EJS43088.1 - 3.8e-12 45.7 4.3 3.8e-12 45.7 3.0 2.4 2 0 0 2 2 2 1 PHD-finger EST1 PF10374.4 EJS43088.1 - 0.012 15.5 0.2 0.055 13.4 0.0 2.1 2 0 0 2 2 2 0 Telomerase activating protein Est1 Lar_restr_allev PF14354.1 EJS43088.1 - 0.25 11.6 3.5 0.68 10.2 0.1 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.2 EJS43088.1 - 0.97 9.3 9.4 10 6.0 3.3 3.2 3 1 0 3 3 3 0 Double zinc ribbon PHD_2 PF13831.1 EJS43088.1 - 3.7 6.9 6.8 0.57 9.5 0.3 2.6 2 0 0 2 2 2 0 PHD-finger ATP-synt_ab PF00006.20 EJS43089.1 - 1.1e-62 211.3 0.0 1.6e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EJS43089.1 - 6.1e-26 91.1 0.3 1.3e-25 90.0 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EJS43089.1 - 4.2e-24 84.5 0.8 1.1e-23 83.2 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 EJS43089.1 - 0.0007 18.7 0.2 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EJS43089.1 - 0.0042 16.4 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EJS43089.1 - 0.013 15.1 0.1 0.57 9.8 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EJS43089.1 - 0.022 14.4 0.1 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 EJS43089.1 - 0.033 13.0 0.8 0.53 9.0 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 EJS43089.1 - 0.036 14.2 0.1 0.52 10.5 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EJS43089.1 - 0.043 13.0 0.1 0.084 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EJS43089.1 - 0.061 13.3 0.6 0.25 11.2 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 EJS43089.1 - 0.083 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EJS43089.1 - 0.088 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EJS43089.1 - 0.089 12.9 0.0 0.33 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Ribosomal_S7 PF00177.16 EJS43090.1 - 1.2e-39 135.2 2.0 1.7e-39 134.7 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MFS_1 PF07690.11 EJS43091.1 - 1.6e-22 79.7 23.9 1.9e-16 59.7 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EJS43091.1 - 7.4e-07 27.9 13.5 7.4e-07 27.9 9.4 2.3 1 1 0 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 EJS43091.1 - 5e-05 22.0 3.2 5e-05 22.0 2.2 3.4 4 0 0 4 4 4 2 Sugar (and other) transporter MFS_1_like PF12832.2 EJS43091.1 - 0.006 16.3 5.4 0.048 13.4 0.1 4.1 4 0 0 4 4 4 1 MFS_1 like family OATP PF03137.15 EJS43091.1 - 0.037 12.0 13.9 0.014 13.4 0.6 2.9 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family ENTH PF01417.15 EJS43092.1 - 2e-44 150.4 0.1 3.3e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EJS43092.1 - 0.0006 18.6 0.0 0.00087 18.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EJS43092.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 VHS domain DUF3991 PF13154.1 EJS43092.1 - 0.064 13.4 0.1 3.8 7.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) Cys_Met_Meta_PP PF01053.15 EJS43093.1 - 4.6e-26 91.0 0.0 1e-25 89.8 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EJS43093.1 - 0.0032 16.4 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II PDE6_gamma PF04868.7 EJS43093.1 - 0.0088 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit RuBisCO_small PF00101.15 EJS43093.1 - 0.078 12.8 0.0 3 7.7 0.1 2.4 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain IBN_N PF03810.14 EJS43094.1 - 2.9e-16 59.1 0.1 4.1e-14 52.2 0.0 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain Pribosyltran PF00156.22 EJS43095.1 - 1e-11 44.6 0.2 8.6e-11 41.6 0.1 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMF_TATA_bd PF12325.3 EJS43096.1 - 4e-36 123.4 20.4 4e-36 123.4 14.1 5.8 3 2 3 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EJS43096.1 - 3.9e-15 55.4 7.6 3.9e-15 55.4 5.3 9.4 5 3 4 9 9 9 1 TATA element modulatory factor 1 DNA binding DUF3584 PF12128.3 EJS43096.1 - 0.0025 15.2 64.6 0.0063 13.9 12.7 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EJS43096.1 - 0.038 12.4 72.9 0.027 12.9 8.6 3.3 2 1 1 3 3 3 0 AAA domain IncA PF04156.9 EJS43096.1 - 0.079 12.5 78.5 0.027 14.0 11.6 4.6 2 1 2 4 4 4 0 IncA protein MtrG PF04210.8 EJS43096.1 - 2.5 7.8 6.1 4.8 6.9 0.3 3.6 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G zf-Tim10_DDP PF02953.10 EJS43098.1 - 4.2e-22 77.1 1.4 5.1e-22 76.9 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EJS43098.1 - 0.026 13.9 1.4 0.035 13.5 1.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2454 PF10521.4 EJS43099.1 - 6.1e-73 245.2 2.3 7.7e-73 244.9 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) NIR_SIR PF01077.17 EJS43100.1 - 3e-58 195.6 0.0 3.4e-54 182.4 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.20 EJS43100.1 - 1.2e-28 99.9 0.0 2.6e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.12 EJS43100.1 - 2.4e-27 94.3 0.1 3.8e-13 48.8 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_NdrI PF07972.6 EJS43100.1 - 0.022 14.6 0.0 0.093 12.6 0.0 2.1 2 0 0 2 2 2 0 NrdI Flavodoxin like POR_N PF01855.14 EJS43100.1 - 0.21 11.0 0.0 0.42 10.0 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF3608 PF12257.3 EJS43101.1 - 3.5e-145 482.1 2.9 5.9e-145 481.4 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EJS43101.1 - 4.3e-26 90.4 0.9 1.2e-25 89.0 0.6 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Homoserine_dh PF00742.14 EJS43102.1 - 1.1e-53 181.5 0.1 1.6e-53 181.0 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EJS43102.1 - 4.9e-28 97.8 0.0 1e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NUDIX PF00293.23 EJS43104.1 - 2.4e-05 23.9 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain PMT PF02366.13 EJS43105.1 - 1.2e-82 277.0 24.0 2.6e-82 275.8 16.6 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EJS43105.1 - 3.9e-25 88.4 0.3 7.3e-25 87.6 0.2 1.4 1 0 0 1 1 1 1 MIR domain Mgm101p PF06420.7 EJS43106.1 - 6e-91 302.3 0.1 7.7e-91 302.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 HSF_DNA-bind PF00447.12 EJS43107.1 - 1.7e-18 66.6 0.4 1.7e-18 66.6 0.3 2.3 2 1 0 2 2 2 1 HSF-type DNA-binding Cortex-I_coil PF09304.5 EJS43107.1 - 0.093 12.7 0.5 0.093 12.7 0.4 1.8 1 1 0 2 2 2 0 Cortexillin I, coiled coil Pup PF05639.6 EJS43107.1 - 0.18 12.3 1.6 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 Pup-like protein PAT1 PF09770.4 EJS43107.1 - 0.2 9.8 14.7 0.28 9.3 10.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MgsA_C PF12002.3 EJS43107.1 - 2.2 7.9 5.0 4.1 7.0 3.5 1.4 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Aminotran_4 PF01063.14 EJS43108.1 - 4.2e-32 111.4 0.0 5.1e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV SRP1_TIP1 PF00660.12 EJS43109.1 - 8.8e-31 105.8 0.1 2.4e-30 104.4 0.1 1.7 1 0 0 1 1 1 1 Seripauperin and TIP1 family FAM196 PF15265.1 EJS43109.1 - 0.7 9.0 14.4 0.91 8.6 10.0 1.1 1 0 0 1 1 1 0 FAM196 family TFIIA PF03153.8 EJS43109.1 - 1.5 8.6 6.7 1.8 8.3 4.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.8 EJS43109.1 - 5.8 6.2 16.2 8.1 5.7 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SLD3 PF08639.5 EJS43109.1 - 6 5.3 13.6 7.2 5.1 9.4 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 PAC2 PF09754.4 EJS43109.1 - 6.1 6.6 8.6 6 6.6 4.1 2.0 1 1 0 2 2 2 0 PAC2 family MCLC PF05934.6 EJS43109.1 - 7.1 4.8 10.7 8.5 4.5 7.4 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) FAD_binding_2 PF00890.19 EJS43110.1 - 9.3e-122 406.8 3.1 1.1e-121 406.5 2.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EJS43110.1 - 3.3e-48 162.8 0.5 5e-48 162.2 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EJS43110.1 - 3e-06 27.2 0.4 0.0011 18.8 0.0 2.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EJS43110.1 - 8.7e-06 24.8 0.3 0.0027 16.6 0.2 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EJS43110.1 - 4.6e-05 22.6 0.1 0.011 14.8 0.0 2.7 3 0 0 3 3 3 2 Thi4 family DAO PF01266.19 EJS43110.1 - 0.00014 20.8 0.6 0.0021 16.9 0.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EJS43110.1 - 0.0047 16.0 0.2 0.011 14.7 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EJS43110.1 - 0.046 12.1 0.5 0.19 10.1 0.1 2.1 3 0 0 3 3 3 0 HI0933-like protein DUF3414 PF11894.3 EJS43112.1 - 0 1583.2 44.1 0 1583.0 30.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DUF1344 PF07076.6 EJS43112.1 - 0.031 13.8 0.0 0.1 12.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Cnd2 PF05786.9 EJS43113.1 - 0.018 13.5 0.3 0.025 13.1 0.2 1.2 1 1 0 1 1 1 0 Condensin complex subunit 2 L31 PF09784.4 EJS43113.1 - 0.046 13.7 1.3 0.079 13.0 0.1 1.8 1 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 FBP PF07299.6 EJS43113.1 - 0.36 10.1 4.7 0.13 11.6 1.6 1.4 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) Drf_GBD PF06371.8 EJS43114.1 - 0.0065 15.8 1.8 0.012 15.0 1.3 1.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain HD_5 PF13487.1 EJS43114.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.8 1 1 1 2 2 2 0 HD domain DUF2175 PF09943.4 EJS43114.1 - 0.76 9.8 3.6 1.8 8.6 2.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) PX PF00787.19 EJS43115.1 - 2.3e-25 88.5 0.2 6.7e-25 87.0 0.1 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EJS43115.1 - 3.2e-07 29.8 13.2 2.1e-05 23.8 1.5 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Nup54 PF13874.1 EJS43115.1 - 0.01 15.5 2.3 0.25 10.9 0.3 2.8 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 BAR PF03114.13 EJS43115.1 - 0.014 14.8 13.8 0.048 13.1 9.5 1.8 1 1 0 1 1 1 0 BAR domain Baculo_PEP_C PF04513.7 EJS43115.1 - 0.025 14.3 1.7 0.3 10.9 0.1 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EJS43115.1 - 0.095 11.3 12.9 0.024 13.2 3.3 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.7 EJS43115.1 - 0.1 12.8 4.3 7.9 6.8 1.7 3.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LSPR PF06049.7 EJS43115.1 - 0.19 11.2 1.0 0.54 9.8 0.7 1.8 1 0 0 1 1 1 0 Coagulation Factor V LSPD Repeat FlaC_arch PF05377.6 EJS43115.1 - 0.36 10.7 5.8 11 6.0 0.1 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 EJS43115.1 - 0.42 10.3 8.4 0.94 9.2 1.5 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ING PF12998.2 EJS43115.1 - 0.57 10.4 9.1 0.064 13.5 1.2 2.8 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding ISG65-75 PF11727.3 EJS43115.1 - 1.3 8.0 9.0 0.25 10.3 2.3 2.5 1 1 1 2 2 2 0 Invariant surface glycoprotein IncA PF04156.9 EJS43115.1 - 2 7.9 12.0 0.15 11.6 1.2 2.5 2 1 0 2 2 2 0 IncA protein DUF1664 PF07889.7 EJS43115.1 - 2.3 8.0 8.7 2.2 8.0 1.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 EJS43115.1 - 2.8 7.8 6.5 1.2 9.0 1.6 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3552 PF12072.3 EJS43115.1 - 3 7.0 10.5 0.65 9.1 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) RPW8 PF05659.6 EJS43115.1 - 4.9 6.6 10.7 4.2 6.8 5.0 2.5 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TMF_TATA_bd PF12325.3 EJS43115.1 - 5.3 6.7 12.1 4.4 7.0 0.8 2.8 3 0 0 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 EJS43115.1 - 8.6 6.7 10.6 1.6 9.1 1.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Atg14 PF10186.4 EJS43115.1 - 9 5.1 9.6 4.3 6.1 0.9 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 dCMP_cyt_deam_1 PF00383.17 EJS43116.1 - 1.9e-21 75.6 0.2 2.6e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EJS43116.1 - 0.00043 20.1 0.4 0.047 13.5 0.3 2.3 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 EJS43116.1 - 0.037 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain MafB19-deam PF14437.1 EJS43116.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 MafB19-like deaminase DUF3525 PF12039.3 EJS43116.1 - 0.13 10.7 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) HSP70 PF00012.15 EJS43117.1 - 3.3e-265 880.6 12.4 3.8e-265 880.4 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EJS43117.1 - 2.8e-18 65.6 1.7 6.5e-17 61.1 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EJS43117.1 - 0.00077 18.6 3.4 0.053 12.6 0.0 3.3 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 EJS43117.1 - 0.022 14.0 0.0 0.32 10.2 0.0 2.3 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DIOX_N PF14226.1 EJS43117.1 - 0.069 13.6 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Evr1_Alr PF04777.8 EJS43117.1 - 0.2 11.5 0.1 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Erv1 / Alr family FtsA PF14450.1 EJS43117.1 - 0.31 10.8 8.0 0.38 10.5 0.8 3.4 2 2 0 2 2 2 0 Cell division protein FtsA DEAD PF00270.24 EJS43118.1 - 9.5e-45 152.1 0.3 3.1e-44 150.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EJS43118.1 - 3.7e-25 87.2 0.1 7.9e-25 86.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EJS43118.1 - 3.6e-23 81.2 0.0 8e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HORMA PF02301.13 EJS43119.1 - 4.4e-45 153.7 0.0 5e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EJS43119.1 - 0.0066 15.9 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 DUF1649 PF07855.7 EJS43119.1 - 0.022 14.4 0.1 0.16 11.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1649) DUF4279 PF14106.1 EJS43119.1 - 0.052 13.4 0.1 0.41 10.5 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4279) V-set_CD47 PF08204.6 EJS43119.1 - 0.075 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain RBD-FIP PF09457.5 EJS43119.1 - 0.15 11.8 0.6 0.29 10.9 0.4 1.5 1 0 0 1 1 1 0 FIP domain Vps53_N PF04100.7 EJS43120.1 - 7.3e-105 350.8 15.1 1.1e-104 350.2 10.5 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DivIVA PF05103.8 EJS43120.1 - 0.039 13.9 0.9 4.1 7.4 0.1 3.0 2 0 0 2 2 2 0 DivIVA protein IncA PF04156.9 EJS43120.1 - 1.6 8.2 5.5 10 5.6 1.6 2.6 2 0 0 2 2 2 0 IncA protein Ribonuc_red_sm PF00268.16 EJS43121.1 - 1.8e-120 401.1 2.1 2.9e-120 400.5 1.5 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.5 EJS43121.1 - 0.13 11.1 0.7 6.3 5.5 0.1 2.1 2 0 0 2 2 2 0 XcyI restriction endonuclease Exonuc_VII_L PF02601.10 EJS43121.1 - 0.13 11.4 1.6 0.18 10.9 1.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3595 PF12166.3 EJS43121.1 - 0.16 10.7 6.5 2 7.1 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3595) RRN7 PF11781.3 EJS43122.1 - 9.5e-10 37.8 0.1 1.9e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 SH3_1 PF00018.23 EJS43123.1 - 3.9e-08 32.5 0.5 1e-07 31.1 0.3 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EJS43123.1 - 4.3e-07 29.3 0.0 8.7e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EJS43123.1 - 0.00019 20.9 0.2 0.00055 19.4 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain Sad1_UNC PF07738.8 EJS43124.1 - 3.8e-05 23.4 8.4 8.7e-05 22.3 0.2 3.7 4 1 0 4 4 4 1 Sad1 / UNC-like C-terminal ARGLU PF15346.1 EJS43124.1 - 0.00079 19.2 3.5 0.002 17.9 2.5 1.6 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 YvrJ PF12841.2 EJS43124.1 - 0.13 11.5 0.8 0.32 10.3 0.1 2.1 2 0 0 2 2 2 0 YvrJ protein family DUF972 PF06156.8 EJS43124.1 - 3.5 8.0 15.9 0.21 11.9 0.7 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Pollen_Ole_e_I PF01190.12 EJS43125.1 - 0.0048 16.6 0.2 0.015 15.0 0.1 1.9 1 0 0 1 1 1 1 Pollen proteins Ole e I like Mad3_BUB1_I PF08311.7 EJS43126.1 - 1.7e-40 137.6 0.5 2.9e-40 136.9 0.3 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 EJS43126.1 - 1.2e-24 85.9 0.0 3.3e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 VTC PF09359.5 EJS43127.1 - 6.3e-104 346.9 1.0 6.7e-104 346.8 0.1 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EJS43127.1 - 3.7e-22 79.3 11.3 1.2e-10 41.6 0.1 3.7 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 EJS43127.1 - 1.8e-07 31.2 2.3 1.8e-07 31.2 1.6 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF202) TFIIF_alpha PF05793.7 EJS43127.1 - 0.034 12.5 0.8 0.063 11.6 0.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_Rpb4 PF03874.11 EJS43128.1 - 2.4e-32 111.3 3.9 2.9e-32 111.1 2.7 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Smoothelin PF12510.3 EJS43128.1 - 0.0016 18.2 0.0 0.0063 16.3 0.0 2.1 1 0 0 1 1 1 1 Smoothelin cytoskeleton protein Cullin PF00888.17 EJS43129.1 - 7.6e-11 41.2 14.9 2.9e-09 36.0 10.3 2.7 1 1 0 1 1 1 1 Cullin family TetR_C_8 PF14278.1 EJS43129.1 - 6.2 7.2 14.2 0.072 13.4 0.9 4.0 4 0 0 4 4 4 0 Transcriptional regulator C-terminal region WD40 PF00400.27 EJS43130.1 - 1.3e-41 138.9 7.9 4.3e-11 42.2 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Mdv1 PF11542.3 EJS43130.1 - 7.5e-26 89.7 1.8 1.7e-25 88.6 0.4 2.2 2 0 0 2 2 2 1 Mitochondrial division protein 1 Nup160 PF11715.3 EJS43130.1 - 2.7e-07 29.1 10.6 0.0046 15.1 0.2 5.0 1 1 2 4 4 4 4 Nucleoporin Nup120/160 BP28CT PF08146.7 EJS43131.1 - 7.3e-42 142.6 9.8 7.6e-42 142.6 1.9 4.5 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EJS43131.1 - 7.3e-24 84.0 1.9 7.3e-24 84.0 1.3 4.4 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.1 EJS43131.1 - 0.0028 18.0 2.7 2.2 8.8 0.1 5.4 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.1 EJS43131.1 - 0.015 15.5 3.1 17 5.8 0.0 6.0 8 0 0 8 8 8 0 HEAT repeats HEAT PF02985.17 EJS43131.1 - 0.19 11.8 5.3 20 5.5 0.0 5.5 5 0 0 5 5 5 0 HEAT repeat DUF1212 PF06738.7 EJS43132.1 - 8.5e-37 126.4 17.0 2.5e-34 118.4 0.1 3.0 3 1 1 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EJS43132.1 - 3.1e-25 88.6 10.1 3.1e-25 88.6 7.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Peptidase_A8 PF01252.13 EJS43132.1 - 0.001 18.6 1.7 0.0029 17.2 1.2 1.8 1 0 0 1 1 1 1 Signal peptidase (SPase) II Pkinase PF00069.20 EJS43133.1 - 5.1e-56 189.6 0.1 1.3e-53 181.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43133.1 - 1e-27 96.9 0.5 7.8e-26 90.6 0.1 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EJS43133.1 - 5.5e-06 25.4 0.6 1.2e-05 24.3 0.2 1.7 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pam16 PF03656.8 EJS43134.1 - 8.1e-57 190.5 0.9 9.5e-57 190.2 0.6 1.0 1 0 0 1 1 1 1 Pam16 Zn_clus PF00172.13 EJS43135.1 - 3.4e-07 30.0 13.4 7.1e-07 29.0 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EJS43135.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.8 1 1 0 1 1 1 0 PAS fold GTP_EFTU PF00009.22 EJS43136.1 - 2.1e-57 193.6 0.1 7.2e-57 191.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EJS43136.1 - 3.1e-26 91.0 0.0 7.2e-26 89.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EJS43136.1 - 1.6e-18 66.3 0.0 3.3e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EJS43136.1 - 8.9e-10 38.5 0.1 2e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EJS43136.1 - 0.0029 17.5 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PI3_PI4_kinase PF00454.22 EJS43137.1 - 4e-74 249.0 0.1 6e-74 248.4 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ChAPs PF09295.5 EJS43138.1 - 1.4e-46 159.0 4.3 3.5e-38 131.4 1.1 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EJS43138.1 - 2.1e-08 33.7 0.0 9.2e-07 28.4 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EJS43138.1 - 4e-05 23.1 0.4 0.069 13.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EJS43138.1 - 0.00023 21.2 1.2 0.0016 18.5 0.3 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EJS43138.1 - 0.001 18.9 0.1 0.016 15.1 0.2 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EJS43138.1 - 0.0014 18.1 0.6 0.0092 15.5 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EJS43138.1 - 0.015 15.6 0.1 0.06 13.6 0.0 2.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EJS43138.1 - 0.021 15.5 0.0 0.069 13.8 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EJS43138.1 - 0.021 14.5 0.1 1.2 9.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SAPS PF04499.10 EJS43139.1 - 4.8e-169 562.9 11.1 4.8e-169 562.9 7.7 3.0 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Syntaxin_2 PF14523.1 EJS43139.1 - 0.056 13.4 0.1 0.35 10.9 0.1 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Ribosomal_L21p PF00829.16 EJS43140.1 - 0.00019 21.4 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ion_trans_2 PF07885.11 EJS43141.1 - 6.5e-27 93.0 23.3 1.4e-17 63.2 5.4 3.7 4 0 0 4 4 4 2 Ion channel GWT1 PF06423.7 EJS43142.1 - 2.7e-46 157.0 2.3 2.7e-46 157.0 1.6 2.5 4 0 0 4 4 4 1 GWT1 BRCT PF00533.21 EJS43143.1 - 1.4e-23 82.8 16.0 1.1e-10 41.5 0.2 5.3 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EJS43143.1 - 7.7e-09 35.2 0.2 2.9e-05 23.8 0.0 4.2 5 0 0 5 5 5 2 twin BRCT domain Zn_clus PF00172.13 EJS43144.1 - 3.2e-11 42.9 11.1 5e-11 42.3 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_lig_T4_1 PF09511.5 EJS43145.1 - 7e-79 264.3 0.8 1.9e-78 262.9 0.0 2.2 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 EJS43145.1 - 9.8e-75 250.0 0.4 9.8e-75 250.0 0.3 2.4 3 0 0 3 3 3 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 EJS43145.1 - 9.7e-56 188.8 4.0 1.3e-55 188.3 2.8 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain ABC_tran PF00005.22 EJS43145.1 - 0.031 14.5 0.1 0.1 12.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 EJS43145.1 - 0.2 11.8 3.3 1.8 8.6 0.4 3.4 3 1 0 3 3 3 0 AAA domain Exo70 PF03081.10 EJS43146.1 - 2.7e-87 292.9 8.0 2.7e-87 292.9 5.5 2.1 2 1 0 2 2 2 1 Exo70 exocyst complex subunit Cytochrom_B562 PF07361.6 EJS43146.1 - 3.5 8.0 8.8 3.2 8.2 0.1 4.0 5 0 0 5 5 5 0 Cytochrome b562 Arrestin_C PF02752.17 EJS43147.1 - 3.3e-14 53.1 5.2 4e-14 52.8 0.1 2.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EJS43147.1 - 1.2e-10 41.3 5.4 6.4e-08 32.5 0.0 3.5 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain EF-hand_4 PF12763.2 EJS43148.1 - 0.00059 19.5 0.1 0.0015 18.2 0.1 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF3808 PF10300.4 EJS43149.1 - 2.8e-158 527.3 0.0 3.4e-158 527.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 EJS43149.1 - 1.5 9.6 8.3 3.7 8.3 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Actin PF00022.14 EJS43150.1 - 5.7e-97 324.6 0.0 5.1e-96 321.4 0.0 1.9 1 1 0 1 1 1 1 Actin KH_1 PF00013.24 EJS43151.1 - 3e-75 247.7 43.9 3.3e-11 42.6 0.2 12.6 13 1 0 13 13 13 8 KH domain KH_3 PF13014.1 EJS43151.1 - 1.1e-50 168.5 32.3 3.8e-09 35.9 0.1 10.8 12 0 0 12 12 12 7 KH domain KH_2 PF07650.12 EJS43151.1 - 2.3e-13 49.4 22.1 0.00035 20.0 0.4 7.3 4 1 2 6 6 6 4 KH domain KH_4 PF13083.1 EJS43151.1 - 2.9e-07 30.0 6.5 1.2 8.7 0.0 6.8 4 1 1 5 5 5 2 KH domain SLS PF14611.1 EJS43151.1 - 3.4e-07 29.8 16.4 0.36 10.2 0.0 8.0 5 3 3 8 8 8 4 Mitochondrial inner-membrane-bound regulator EMP24_GP25L PF01105.19 EJS43151.1 - 0.15 11.7 0.0 0.15 11.7 0.0 3.1 4 1 0 4 4 4 0 emp24/gp25L/p24 family/GOLD CAP PF00188.21 EJS43152.1 - 1.2e-22 80.6 1.9 1.2e-22 80.6 1.3 2.3 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF3306 PF11748.3 EJS43152.1 - 0.088 13.4 6.6 0.067 13.8 3.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3306) DUF2413 PF10310.4 EJS43152.1 - 0.26 10.0 9.0 0.34 9.6 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Dicty_REP PF05086.7 EJS43152.1 - 0.56 7.8 6.3 0.72 7.5 4.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.3 EJS43152.1 - 5 6.2 23.4 6 5.9 16.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Macoilin PF09726.4 EJS43152.1 - 8 4.6 10.2 9.3 4.3 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein CAP PF00188.21 EJS43153.1 - 4.2e-22 78.9 2.8 4.2e-22 78.9 1.9 4.0 4 0 0 4 4 4 1 Cysteine-rich secretory protein family Cytokin_check_N PF10407.4 EJS43154.1 - 2.2e-30 104.0 2.5 5.5e-30 102.8 1.7 1.7 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus SMC_N PF02463.14 EJS43155.1 - 2.2e-54 184.0 54.7 1.7e-53 181.1 37.9 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EJS43155.1 - 1e-29 102.9 0.0 7.2e-29 100.2 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EJS43155.1 - 1.2e-13 51.7 6.1 2.8e-09 37.3 1.8 5.2 3 2 1 5 5 5 2 AAA domain AAA_23 PF13476.1 EJS43155.1 - 2.5e-10 41.0 33.8 2.5e-10 41.0 23.4 8.0 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 EJS43155.1 - 0.00053 19.4 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.4 EJS43155.1 - 0.0066 16.5 3.0 0.0066 16.5 2.1 9.2 7 1 1 8 8 8 4 Biogenesis of lysosome-related organelles complex-1 subunit 2 DnaJ PF00226.26 EJS43156.1 - 3e-22 78.1 4.4 7e-22 76.9 3.1 1.7 1 0 0 1 1 1 1 DnaJ domain Sld5 PF05916.6 EJS43157.1 - 2.1e-17 63.3 1.2 3.9e-17 62.4 0.8 1.4 1 0 0 1 1 1 1 GINS complex protein DUF790 PF05626.6 EJS43157.1 - 0.016 13.7 0.0 0.021 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF790) A_deaminase PF00962.17 EJS43158.1 - 6.7e-20 71.2 0.0 6.4e-13 48.3 0.0 3.5 3 1 0 3 3 3 2 Adenosine/AMP deaminase WD40 PF00400.27 EJS43159.1 - 4.1e-16 58.1 0.4 4.1e-06 26.4 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EJS43159.1 - 0.00011 21.6 0.0 0.0015 18.0 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Esterase PF00756.15 EJS43160.1 - 5.5e-70 235.6 0.2 6.3e-70 235.4 0.1 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EJS43160.1 - 5.4e-06 26.2 0.0 7.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EJS43160.1 - 0.0067 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EJS43160.1 - 0.024 14.5 0.0 0.032 14.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EJS43160.1 - 0.045 12.6 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.8 EJS43160.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein CBFD_NFYB_HMF PF00808.18 EJS43162.1 - 3.9e-06 26.8 0.0 9.3e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4411 PF14367.1 EJS43162.1 - 0.031 13.9 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Ribosomal_L17 PF01196.14 EJS43163.1 - 3.7e-28 97.9 0.1 9.3e-28 96.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 mIF3 PF14877.1 EJS43163.1 - 0.19 11.0 1.7 0.17 11.2 0.2 1.5 2 0 0 2 2 2 0 Mitochondrial translation initiation factor Phosphodiest PF01663.17 EJS43165.1 - 5e-12 45.8 3.9 6.7e-09 35.5 0.5 2.3 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EJS43165.1 - 0.00028 20.1 0.1 0.00053 19.2 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EJS43165.1 - 0.012 14.9 0.4 0.02 14.2 0.3 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Aminotran_1_2 PF00155.16 EJS43166.1 - 6.1e-92 308.3 0.0 7.2e-92 308.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EJS43166.1 - 6.1e-07 28.8 0.0 9.2e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EJS43166.1 - 5.3e-05 21.6 0.2 0.00016 20.1 0.1 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EJS43166.1 - 0.00048 18.9 0.1 0.0022 16.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EJS43166.1 - 0.0052 15.9 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 EJS43166.1 - 0.011 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III DUF2240 PF09999.4 EJS43166.1 - 0.049 13.0 0.0 0.092 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) CLN3 PF02487.12 EJS43167.1 - 1e-182 607.4 22.4 1e-181 604.1 15.5 1.9 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 EJS43167.1 - 0.0034 16.1 21.9 0.032 12.9 15.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Pex24p PF06398.6 EJS43167.1 - 0.29 9.8 2.7 0.17 10.6 0.3 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin HbrB PF08539.6 EJS43168.1 - 6.6e-42 143.0 0.6 1.1e-41 142.2 0.4 1.4 1 0 0 1 1 1 1 HbrB-like Imm28 PF15574.1 EJS43168.1 - 0.038 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 28 Pkinase PF00069.20 EJS43169.1 - 2.1e-35 122.1 0.0 4.6e-35 121.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43169.1 - 9.9e-19 67.4 0.0 5.6e-18 64.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase zf-C2H2 PF00096.21 EJS43170.1 - 3.2e-22 77.4 71.6 5.1e-06 26.5 0.8 9.2 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EJS43170.1 - 2.2e-20 71.8 61.5 6.7e-09 35.6 0.2 8.7 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EJS43170.1 - 9.9e-11 41.1 64.2 0.0018 18.4 0.3 9.4 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EJS43170.1 - 6.3e-10 38.6 36.5 0.003 17.3 1.4 6.8 5 1 1 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EJS43170.1 - 4.5e-06 26.6 38.7 0.0095 16.0 1.8 7.1 5 1 1 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EJS43170.1 - 0.079 12.6 18.9 0.2 11.3 0.1 5.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Phage_Orf51 PF06194.6 EJS43170.1 - 0.58 10.3 7.1 18 5.5 0.0 3.5 3 0 0 3 3 3 0 Phage Conserved Open Reading Frame 51 zf-met PF12874.2 EJS43170.1 - 2.3 8.5 51.4 0.19 12.0 2.3 7.6 8 0 0 8 8 8 0 Zinc-finger of C2H2 type Vps26 PF03643.10 EJS43171.1 - 3.9e-123 409.6 0.3 4.6e-123 409.3 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EJS43171.1 - 2.9e-05 23.9 0.2 0.00029 20.6 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EJS43171.1 - 0.0008 19.5 0.0 0.0052 16.8 0.0 2.2 1 1 1 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Gp_dh_C PF02800.15 EJS43172.1 - 6.8e-74 246.5 0.0 9.6e-74 246.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EJS43172.1 - 1.6e-59 200.1 0.1 2.7e-59 199.4 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EJS43172.1 - 0.0041 17.0 0.4 0.021 14.7 0.2 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 EJS43172.1 - 0.1 12.6 0.2 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain PAP2 PF01569.16 EJS43173.1 - 3.4e-16 59.0 2.5 8.8e-16 57.7 1.8 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EJS43173.1 - 0.023 14.2 1.5 0.023 14.2 1.0 1.8 2 0 0 2 2 2 0 PAP2 superfamily Mito_carr PF00153.22 EJS43175.1 - 1.1e-65 217.3 3.5 1e-23 82.8 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein mIF3 PF14877.1 EJS43176.1 - 6.9e-65 217.7 12.6 6.9e-65 217.7 8.8 1.7 2 0 0 2 2 2 1 Mitochondrial translation initiation factor IF3_C PF00707.17 EJS43176.1 - 0.0015 18.2 1.1 0.0051 16.5 0.2 2.4 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain CPSase_L_D2 PF02786.12 EJS43177.1 - 3.8e-114 379.2 0.8 5.5e-83 277.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EJS43177.1 - 1.1e-46 157.5 0.0 3.2e-46 156.0 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EJS43177.1 - 2.1e-44 151.2 0.0 4.3e-44 150.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EJS43177.1 - 3.2e-41 140.2 0.5 7.7e-41 139.0 0.0 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EJS43177.1 - 1.2e-40 138.0 0.1 4.2e-40 136.3 0.1 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EJS43177.1 - 3.5e-40 136.5 0.2 8.7e-20 70.8 0.0 3.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 EJS43177.1 - 8.2e-35 120.0 0.0 7.3e-34 116.9 0.0 2.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EJS43177.1 - 1.7e-33 115.9 0.2 4.9e-21 75.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EJS43177.1 - 2.6e-24 85.5 0.3 5.2e-14 51.7 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EJS43177.1 - 1.2e-22 79.5 0.0 8e-22 76.9 0.0 2.6 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EJS43177.1 - 2.7e-16 59.5 3.4 1.6e-09 37.4 0.2 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EJS43177.1 - 7e-15 54.7 0.6 1.4e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EJS43177.1 - 3.4e-07 29.9 0.5 1.1e-05 24.9 0.1 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EJS43177.1 - 5.1e-06 26.4 1.4 0.016 15.0 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EJS43177.1 - 3.1e-05 23.5 0.0 0.00067 19.1 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 TrkA_N PF02254.13 EJS43177.1 - 0.18 11.8 2.8 0.56 10.2 0.0 3.0 3 0 0 3 3 3 0 TrkA-N domain Pkinase PF00069.20 EJS43178.1 - 5.2e-55 186.3 0.0 7.9e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43178.1 - 1.9e-36 125.4 0.0 2.8e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43178.1 - 9.1e-05 21.5 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EJS43178.1 - 0.00064 18.6 0.1 0.001 17.9 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EJS43178.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TAT_signal PF10518.4 EJS43179.1 - 0.012 15.5 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence zf-H2C2 PF09337.5 EJS43180.1 - 2e-21 75.1 4.2 3.5e-21 74.3 2.9 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EJS43180.1 - 6e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EJS43180.1 - 0.00072 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CN_hydrolase PF00795.17 EJS43181.1 - 2.3e-28 98.8 0.0 3.1e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GCD14 PF08704.5 EJS43182.1 - 1.9e-82 276.5 0.3 1.5e-81 273.5 0.2 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EJS43182.1 - 9.2e-05 22.4 0.0 0.00016 21.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EJS43182.1 - 0.00022 20.3 0.0 0.00045 19.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 EJS43182.1 - 0.00046 20.7 0.0 0.0012 19.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Gcd10p PF04189.8 EJS43182.1 - 0.0037 16.4 0.0 0.0097 15.0 0.0 1.6 2 0 0 2 2 2 1 Gcd10p family Methyltransf_31 PF13847.1 EJS43182.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EJS43182.1 - 0.016 14.7 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3748 PF12566.3 EJS43182.1 - 0.019 14.8 0.1 0.039 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) LSM PF01423.17 EJS43183.1 - 1.8e-14 53.0 0.1 3.2e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 LSM domain Alb1 PF09135.6 EJS43184.1 - 6.6e-20 71.7 8.2 6.6e-20 71.7 5.7 1.6 2 0 0 2 2 2 1 Alb1 Ribul_P_3_epim PF00834.14 EJS43185.1 - 2.5e-69 232.4 0.0 4e-69 231.7 0.0 1.3 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 EJS43185.1 - 0.0029 17.0 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.12 EJS43185.1 - 0.026 13.7 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 PcrB family QRPTase_C PF01729.14 EJS43185.1 - 0.037 13.5 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EJS43185.1 - 0.12 11.6 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein Pho86 PF11124.3 EJS43186.1 - 9.9e-104 346.5 0.5 1.1e-103 346.3 0.3 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Lysis_S PF04971.7 EJS43186.1 - 0.04 13.5 1.3 2.1 8.1 0.1 2.5 1 1 1 2 2 2 0 Lysis protein S DUF3203 PF11462.3 EJS43186.1 - 0.052 13.4 0.1 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) SUN PF03856.8 EJS43187.1 - 4e-105 350.5 16.6 5.1e-105 350.2 11.5 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) ASF1_hist_chap PF04729.8 EJS43188.1 - 2e-67 225.6 0.1 2.8e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 EJS43188.1 - 2.9 5.7 49.4 3.6 5.3 34.2 1.1 1 0 0 1 1 1 0 Nop14-like family Amidohydro_1 PF01979.15 EJS43189.1 - 6.8e-26 91.7 0.0 1.2e-25 90.9 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EJS43189.1 - 5.5e-10 39.0 0.0 1.1e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EJS43189.1 - 5.2e-08 33.2 0.0 2.9e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase zf-RING_UBOX PF13445.1 EJS43189.1 - 0.093 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger OPT PF03169.10 EJS43190.1 - 9.5e-153 509.9 43.3 1.2e-152 509.6 30.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4179 PF13786.1 EJS43190.1 - 0.84 9.8 6.7 3.5 7.9 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Pex2_Pex12 PF04757.9 EJS43191.1 - 2.8e-18 66.1 0.8 4.6e-18 65.4 0.6 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EJS43191.1 - 0.5 10.4 13.4 2 8.5 7.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans PF04082.13 EJS43194.1 - 7.2e-38 129.9 1.2 1.8e-37 128.6 0.9 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS43194.1 - 3.9e-09 36.2 13.4 7.4e-09 35.3 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPOB_ab PF14682.1 EJS43194.1 - 0.0066 16.2 2.9 0.27 11.0 1.1 2.5 2 0 0 2 2 2 1 Sporulation initiation phospho-transferase B, C-terminal Surf_Ag_VNR PF07244.10 EJS43194.1 - 0.01 16.2 0.1 0.03 14.7 0.1 1.8 1 0 0 1 1 1 0 Surface antigen variable number repeat DUF4557 PF15101.1 EJS43194.1 - 0.18 11.6 5.9 0.25 11.1 3.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Sec10 PF07393.6 EJS43195.1 - 3.7e-65 220.4 23.4 4.6e-65 220.1 16.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Surp PF01805.15 EJS43196.1 - 2.5e-14 52.6 2.5 5e-09 35.6 0.0 3.1 4 0 0 4 4 4 2 Surp module PRP21_like_P PF12230.3 EJS43196.1 - 3.8e-08 33.1 4.7 1e-07 31.7 3.3 1.7 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein ECSIT PF06239.6 EJS43196.1 - 0.013 14.3 0.1 0.025 13.4 0.0 1.5 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF3974 PF13120.1 EJS43196.1 - 0.028 14.2 0.9 0.47 10.2 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3974) CRAL_TRIO_2 PF13716.1 EJS43197.1 - 5.1e-31 107.5 1.1 1.4e-30 106.1 0.8 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EJS43197.1 - 2.1e-08 33.9 0.3 6.5e-08 32.3 0.2 1.8 1 0 0 1 1 1 1 RhoGAP domain DUF3641 PF12345.3 EJS43197.1 - 0.015 15.1 0.1 0.046 13.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3641) CCDC74_C PF14917.1 EJS43197.1 - 0.015 15.3 0.9 0.039 13.9 0.6 1.7 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal DUF1140 PF06600.6 EJS43197.1 - 0.31 11.1 6.9 2.1 8.5 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) Aconitase PF00330.15 EJS43198.1 - 2.5e-179 596.6 0.0 7.7e-179 595.0 0.0 1.8 2 0 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EJS43198.1 - 1.3e-42 144.9 0.0 2.4e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 EJS43198.1 - 0.025 13.1 0.0 0.039 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) SPX PF03105.14 EJS43199.1 - 7.5e-42 143.9 4.2 1.5e-41 143.0 2.9 1.5 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EJS43199.1 - 2.3e-20 72.9 39.5 3.2e-20 72.4 27.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EJS43199.1 - 1.3e-17 63.3 41.1 5e-14 51.6 17.3 2.2 1 1 1 2 2 2 2 Citrate transporter DctM PF06808.7 EJS43199.1 - 0.00013 20.6 35.0 0.03 12.8 12.4 2.5 1 1 1 2 2 2 2 DctM-like transporters UCH PF00443.24 EJS43200.1 - 1e-97 326.4 2.8 7.6e-96 320.3 1.9 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EJS43200.1 - 1.2e-19 70.9 2.3 4.2e-11 42.8 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EJS43200.1 - 5.4e-05 23.5 0.1 0.00049 20.4 0.0 2.7 2 0 0 2 2 2 1 DUSP domain AAA_22 PF13401.1 EJS43201.1 - 1.6e-11 44.4 0.0 5.3e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EJS43201.1 - 5.2e-10 39.6 0.1 3.1e-09 37.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EJS43201.1 - 1.4e-07 31.6 0.0 5.6e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Cdc6_C PF09079.6 EJS43201.1 - 0.00031 20.4 0.0 0.00075 19.1 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal NACHT PF05729.7 EJS43201.1 - 0.0016 18.0 0.2 0.84 9.2 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 EJS43201.1 - 0.0025 17.5 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AFG1_ATPase PF03969.11 EJS43201.1 - 0.0079 15.0 0.0 0.24 10.1 0.0 2.2 2 0 0 2 2 2 1 AFG1-like ATPase PIF1 PF05970.9 EJS43201.1 - 0.0089 15.0 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase KAP_NTPase PF07693.9 EJS43201.1 - 0.015 14.2 0.0 0.26 10.2 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Arch_ATPase PF01637.13 EJS43201.1 - 0.016 14.9 0.0 0.1 12.2 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EJS43201.1 - 0.043 13.7 0.0 5.1 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EJS43201.1 - 0.06 12.9 1.5 0.23 11.0 1.1 2.0 1 1 0 1 1 1 0 AAA domain Streptin-Immun PF11083.3 EJS43201.1 - 0.063 13.2 0.2 0.25 11.3 0.1 2.0 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein TPT PF03151.11 EJS43202.1 - 8.2e-45 152.1 7.1 8.2e-45 152.1 4.9 2.9 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EJS43202.1 - 1.1e-05 24.5 7.5 1.1e-05 24.5 5.2 2.4 3 0 0 3 3 3 1 UAA transporter family EamA PF00892.15 EJS43202.1 - 0.01 15.8 34.9 0.22 11.5 10.3 3.6 2 2 1 3 3 3 0 EamA-like transporter family Nuc_sug_transp PF04142.10 EJS43202.1 - 1.3 8.0 12.8 1 8.3 1.2 2.6 3 0 0 3 3 3 0 Nucleotide-sugar transporter Ribosomal_S8 PF00410.14 EJS43203.1 - 3.5e-26 91.5 0.1 4.8e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glyco_transf_34 PF05637.7 EJS43205.1 - 7.3e-67 225.3 0.0 9.9e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ATP12 PF07542.6 EJS43206.1 - 9.1e-29 99.8 0.0 1.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Prefoldin_2 PF01920.15 EJS43207.1 - 1.5e-13 50.4 6.6 1.7e-13 50.2 4.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit PLAC9 PF15205.1 EJS43207.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Placenta-specific protein 9 YscO PF07321.7 EJS43207.1 - 0.3 10.8 3.7 1.3 8.8 0.8 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO Laminin_II PF06009.7 EJS43207.1 - 3.4 7.4 7.5 58 3.4 5.2 2.0 1 1 0 1 1 1 0 Laminin Domain II ATG27 PF09451.5 EJS43208.1 - 5.2e-72 242.3 0.9 6.1e-72 242.0 0.6 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 UPF0233 PF06781.7 EJS43208.1 - 0.025 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) ABA_GPCR PF12430.3 EJS43208.1 - 0.097 11.8 1.1 0.64 9.1 0.2 2.4 3 0 0 3 3 3 0 Abscisic acid G-protein coupled receptor SWIRM PF04433.12 EJS43209.1 - 1.7e-31 108.1 1.2 3.7e-31 107.0 0.1 2.2 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EJS43209.1 - 4.2e-10 39.5 0.0 8.3e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EJS43209.1 - 3.6e-08 33.3 0.0 1.1e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain CRAL_TRIO_N PF03765.10 EJS43209.1 - 0.36 11.0 4.2 0.73 10.0 0.0 3.3 3 0 0 3 3 3 0 CRAL/TRIO, N-terminal domain KRE9 PF05390.6 EJS43210.1 - 5.3e-56 187.5 9.5 5.3e-56 187.5 6.6 2.6 2 1 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 EJS43210.1 - 1.5e-11 44.5 2.5 1.5e-11 44.5 1.7 3.0 2 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4124 PF13511.1 EJS43210.1 - 1 9.4 7.7 1.5 8.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) Rep_fac-A_3 PF08661.6 EJS43211.1 - 4.1e-33 113.5 0.0 4.6e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Peptidase_M20 PF01546.23 EJS43212.1 - 1.7e-25 89.6 0.0 2.2e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EJS43212.1 - 1.9e-19 69.4 0.0 3.3e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2401 PF10287.4 EJS43213.1 - 1.1e-93 313.0 3.4 1.6e-93 312.5 2.4 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EJS43213.1 - 8.3e-26 89.9 0.1 2.6e-25 88.3 0.0 1.9 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SRI PF08236.6 EJS43214.1 - 1.5e-26 92.1 6.8 1.5e-26 92.1 4.7 2.8 1 1 1 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 EJS43214.1 - 4.8e-23 82.2 0.3 4.8e-23 82.2 0.2 3.4 3 1 0 3 3 3 1 SET domain WW PF00397.21 EJS43214.1 - 0.029 14.2 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 WW domain Antimicrobial_7 PF08102.6 EJS43214.1 - 0.11 12.5 3.6 8.8 6.4 0.0 3.2 2 0 0 2 2 2 0 Scorpion antimicrobial peptide DUF3677 PF12432.3 EJS43214.1 - 0.34 11.3 4.2 1.2 9.6 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) LMBR1 PF04791.11 EJS43214.1 - 8.4 4.8 7.2 15 4.0 5.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein polyprenyl_synt PF00348.12 EJS43215.1 - 3.8e-89 297.9 0.1 4.5e-89 297.7 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase UcrQ PF02939.11 EJS43216.1 - 7.9e-40 134.5 2.2 9.1e-40 134.3 1.5 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 EJS43216.1 - 0.028 14.5 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) Pkinase PF00069.20 EJS43217.1 - 1.6e-45 155.2 0.0 8.2e-43 146.4 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43217.1 - 3.1e-18 65.8 0.0 1.3e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43217.1 - 0.0032 16.4 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EJS43217.1 - 0.085 11.9 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS43217.1 - 0.19 11.4 0.1 0.64 9.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EJS43218.1 - 1.5e-70 237.3 0.0 1.9e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43218.1 - 3.6e-40 137.6 0.0 5e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43218.1 - 3.7e-05 22.8 0.0 5.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EJS43218.1 - 0.057 13.1 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EJS43218.1 - 0.067 12.0 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EJS43218.1 - 0.095 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C37 PF05416.7 EJS43218.1 - 0.42 8.8 3.8 0.55 8.4 2.6 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase MFS_1 PF07690.11 EJS43219.1 - 2.4e-21 75.8 32.9 1.4e-19 70.0 14.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF928 PF06051.7 EJS43219.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) PIR PF00399.14 EJS43221.1 - 4.2e-32 108.4 38.1 2.6e-08 32.9 0.8 4.6 4 0 0 4 4 4 4 Yeast PIR protein repeat Macoilin PF09726.4 EJS43221.1 - 0.15 10.2 1.2 0.35 9.1 0.8 1.4 1 1 1 2 2 2 0 Transmembrane protein PIR PF00399.14 EJS43222.1 - 9.6e-67 218.2 141.0 3.9e-08 32.3 5.2 9.9 9 0 0 9 9 9 9 Yeast PIR protein repeat DUF2072 PF09845.4 EJS43222.1 - 0.096 12.6 1.2 0.19 11.6 0.0 2.1 1 1 2 3 3 3 0 Zn-ribbon containing protein (DUF2072) MU117 PF15474.1 EJS43222.1 - 7.3 7.1 11.0 22 5.6 0.5 3.4 1 1 1 2 2 2 0 Meiotically up-regulated gene family PIR PF00399.14 EJS43223.1 - 8.4e-07 28.1 5.9 8.4e-07 28.1 4.1 3.1 2 0 0 2 2 2 2 Yeast PIR protein repeat DUF2217 PF10265.4 EJS43223.1 - 1.2 7.7 3.8 1.6 7.3 2.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 EJS43223.1 - 2.2 6.4 5.2 2.6 6.2 3.6 1.0 1 0 0 1 1 1 0 Transmembrane protein 6PF2K PF01591.13 EJS43224.1 - 5.2e-89 297.1 0.2 7.4e-89 296.6 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EJS43224.1 - 7.2e-33 113.9 0.1 1.3e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EJS43224.1 - 8e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EJS43224.1 - 0.00048 20.9 0.3 0.0095 16.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain Vps35 PF03635.12 EJS43225.1 - 7e-282 937.1 33.0 8.2e-282 936.9 22.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 NAD_binding_5 PF07994.7 EJS43226.1 - 1.3e-117 392.5 0.0 1.5e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EJS43226.1 - 1e-44 150.9 0.4 2.4e-44 149.7 0.3 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase F-box-like PF12937.2 EJS43227.1 - 1.2e-08 34.4 0.1 3.8e-08 32.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EJS43227.1 - 0.00017 21.1 0.1 0.00076 19.0 0.0 2.2 1 0 0 1 1 1 1 F-box domain DivIC PF04977.10 EJS43227.1 - 0.57 9.7 3.3 10 5.6 0.1 2.8 3 0 0 3 3 3 0 Septum formation initiator Ecl1 PF12855.2 EJS43229.1 - 0.065 12.5 0.3 0.14 11.4 0.2 1.5 1 0 0 1 1 1 0 Life-span regulatory factor CRAL_TRIO PF00650.15 EJS43230.1 - 1.7e-26 92.6 0.2 5.1e-26 91.0 0.1 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EJS43230.1 - 1.8e-15 56.8 0.3 4.8e-15 55.4 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Tim17 PF02466.14 EJS43232.1 - 1.3e-32 112.5 4.2 1.5e-32 112.2 2.9 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 EJS43233.1 - 3.2e-53 180.5 0.0 9.4e-53 178.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43233.1 - 7.9e-21 74.2 0.0 1.3e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EJS43233.1 - 0.0018 17.6 0.0 0.004 16.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EJS43233.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EJS43233.1 - 0.048 13.2 5.9 0.056 13.0 0.1 3.0 2 1 1 3 3 3 0 Choline/ethanolamine kinase RNA_pol_Rpb4 PF03874.11 EJS43234.1 - 2.7e-36 124.1 9.2 2.7e-35 120.8 6.4 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb4 IncFII_repA PF02387.10 EJS43234.1 - 0.013 14.6 7.6 0.021 14.0 5.3 1.4 1 0 0 1 1 1 0 IncFII RepA protein family Rtf2 PF04641.7 EJS43234.1 - 0.051 12.7 8.1 0.066 12.4 5.6 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger RXT2_N PF08595.6 EJS43234.1 - 0.076 12.8 8.0 0.13 12.0 5.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TRAP_alpha PF03896.11 EJS43234.1 - 0.28 10.1 4.7 0.41 9.5 3.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tom37_C PF11801.3 EJS43234.1 - 0.37 10.6 10.4 0.027 14.3 3.0 1.9 1 1 1 2 2 2 0 Tom37 C-terminal domain FLO_LFY PF01698.11 EJS43234.1 - 0.44 9.3 10.3 0.56 8.9 7.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Cellulose_synt PF03552.9 EJS43234.1 - 0.46 8.7 2.1 0.55 8.4 1.5 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF2457 PF10446.4 EJS43234.1 - 0.73 8.4 13.8 1.1 7.9 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3295 PF11702.3 EJS43234.1 - 0.87 8.4 8.4 30 3.4 6.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3295) DUF1754 PF08555.5 EJS43234.1 - 3.6 8.2 12.8 1 9.9 6.6 1.8 1 1 1 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PBP1_TM PF14812.1 EJS43234.1 - 5.2 7.4 12.9 5 7.5 7.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_15 PF01793.11 EJS43235.1 - 8e-131 435.8 10.5 9.7e-131 435.6 7.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase MFS_1 PF07690.11 EJS43236.1 - 6.8e-16 57.9 48.2 4.6e-15 55.1 27.1 3.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EJS43236.1 - 7.1e-07 27.8 21.3 9.8e-07 27.3 14.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ydc2-catalyt PF09159.5 EJS43237.1 - 1.1e-19 71.0 0.0 1.2e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 DUF3015 PF11220.3 EJS43237.1 - 0.15 11.6 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) Peptidase_S24 PF00717.18 EJS43238.1 - 1.2e-08 34.4 0.1 2.2e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like Fungal_trans PF04082.13 EJS43239.1 - 7.2e-32 110.2 3.4 7.2e-32 110.2 2.3 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS43239.1 - 7.3e-07 28.9 7.0 1.6e-06 27.9 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ScpA_ScpB PF02616.9 EJS43240.1 - 0.0056 16.2 1.4 0.0077 15.8 1.0 1.3 1 0 0 1 1 1 1 ScpA/B protein DUF2433 PF10360.4 EJS43240.1 - 0.18 12.1 1.1 0.8 10.0 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) Apc15p PF05841.6 EJS43241.1 - 1.2e-25 90.7 0.4 1.2e-25 90.7 0.3 1.9 2 0 0 2 2 2 1 Apc15p protein Transp_cyt_pur PF02133.10 EJS43242.1 - 9e-181 601.2 36.3 1.1e-180 600.9 25.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Allantoicase PF03561.10 EJS43243.1 - 2.8e-107 354.7 0.6 4e-57 191.9 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Asp_Glu_race PF01177.17 EJS43244.1 - 4.3e-19 69.2 0.0 5e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Malate_synthase PF01274.17 EJS43245.1 - 5.4e-223 740.7 0.0 6.4e-223 740.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Ank PF00023.25 EJS43246.1 - 1.4e-13 49.8 0.1 1.4e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EJS43246.1 - 2.9e-11 43.5 0.1 7.7e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EJS43246.1 - 9.1e-11 41.9 0.1 1.7e-09 37.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EJS43246.1 - 2.7e-09 36.9 2.6 8.9e-07 28.9 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EJS43246.1 - 4.9e-09 35.5 0.3 0.00047 20.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 EJS43246.1 - 1.1e-07 31.7 1.0 1.1e-07 31.7 0.7 2.2 2 0 0 2 2 2 1 IPT/TIG domain AlaDh_PNT_N PF05222.10 EJS43247.1 - 6.8e-31 107.0 0.0 9.9e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EJS43247.1 - 3.3e-13 49.5 0.0 4.5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 EJS43248.1 - 2.3e-28 99.2 0.0 2.8e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EJS43248.1 - 4.4e-15 56.1 0.1 5.4e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EJS43248.1 - 1.3e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EJS43248.1 - 0.00021 20.8 0.2 0.00087 18.7 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EJS43248.1 - 0.0078 16.2 0.1 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 EJS43248.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding tRNA_m1G_MT PF01746.16 EJS43248.1 - 0.056 13.0 0.1 0.096 12.2 0.1 1.4 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase DUF1776 PF08643.5 EJS43248.1 - 0.13 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GSHPx PF00255.14 EJS43249.1 - 3.6e-49 164.6 0.2 4.8e-49 164.2 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EJS43249.1 - 6.4e-06 25.8 0.1 3.1e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EJS43249.1 - 1.2e-05 24.9 0.0 4.6e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 EJS43249.1 - 0.0017 18.3 0.0 0.0041 17.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4174) SCO1-SenC PF02630.9 EJS43249.1 - 0.036 13.6 0.2 0.46 10.0 0.0 2.2 2 1 0 2 2 2 0 SCO1/SenC GST_N PF02798.15 EJS43250.1 - 4.2e-15 55.6 0.0 7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EJS43250.1 - 2.8e-12 46.4 0.0 4.3e-12 45.8 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EJS43250.1 - 1e-07 32.0 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EJS43250.1 - 2.1e-07 30.8 0.0 7.3e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EJS43250.1 - 0.0019 18.6 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EJS43250.1 - 0.0063 16.3 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AhpC-TSA PF00578.16 EJS43251.1 - 8.1e-27 93.3 0.0 1.2e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EJS43251.1 - 5.1e-18 65.0 0.0 6.6e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EJS43251.1 - 0.017 15.0 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF1644 PF07800.7 EJS43251.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) AMP-binding PF00501.23 EJS43252.1 - 4.8e-72 242.6 0.0 6.8e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EJS43252.1 - 0.023 15.6 0.1 0.083 13.8 0.0 2.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Urm1 PF09138.6 EJS43253.1 - 3.2e-34 116.9 0.5 3.5e-34 116.7 0.3 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EJS43253.1 - 0.00031 21.1 0.0 0.00043 20.6 0.0 1.3 1 0 0 1 1 1 1 ThiS family YchF-GTPase_C PF06071.8 EJS43253.1 - 0.069 12.9 0.1 0.09 12.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF933) PDZ PF00595.19 EJS43254.1 - 1.1e-10 41.5 0.1 2e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EJS43254.1 - 1.7e-06 27.8 0.1 3.2e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 EJS43254.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Mito_carr PF00153.22 EJS43255.1 - 3.4e-71 235.0 0.4 4.9e-25 87.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Thioredoxin PF00085.15 EJS43256.1 - 1.6e-28 98.4 1.0 7.1e-22 77.0 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 EJS43256.1 - 1.4e-06 28.2 5.2 0.0005 19.9 0.4 3.5 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EJS43256.1 - 0.0046 17.0 0.6 0.08 13.0 0.0 3.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.1 EJS43256.1 - 0.021 14.8 2.3 0.39 10.7 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin TSLP PF15216.1 EJS43256.1 - 0.1 12.3 1.1 0.35 10.6 0.0 2.3 2 1 0 2 2 2 0 Thymic stromal lymphopoietin Thioredoxin_2 PF13098.1 EJS43256.1 - 0.26 11.4 5.8 2.2 8.4 0.2 3.8 4 2 0 4 4 4 0 Thioredoxin-like domain HR1 PF02185.11 EJS43257.1 - 0.0003 20.4 1.6 0.00033 20.3 1.1 1.1 1 0 0 1 1 1 1 Hr1 repeat Myosin_tail_1 PF01576.14 EJS43257.1 - 0.0056 14.4 0.4 0.0056 14.4 0.3 1.0 1 0 0 1 1 1 1 Myosin tail DUF948 PF06103.6 EJS43257.1 - 0.042 13.7 0.2 0.048 13.5 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Viral_P18 PF04521.8 EJS43257.1 - 0.058 12.8 0.2 0.061 12.7 0.1 1.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein FlaC_arch PF05377.6 EJS43257.1 - 0.085 12.7 0.3 0.085 12.7 0.2 1.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RBD-FIP PF09457.5 EJS43257.1 - 0.31 10.8 2.6 0.5 10.2 1.8 1.3 1 0 0 1 1 1 0 FIP domain Syja_N PF02383.13 EJS43258.1 - 2.6e-62 210.4 0.7 2.6e-62 210.4 0.5 2.1 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.18 EJS43258.1 - 4.8e-24 85.6 0.0 7.8e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BTB PF00651.26 EJS43259.1 - 5.9e-27 93.8 1.4 1.3e-18 66.9 0.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain Ank PF00023.25 EJS43259.1 - 1.6e-10 40.2 0.5 9.5e-07 28.3 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EJS43259.1 - 8.2e-10 38.9 0.0 4.3e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EJS43259.1 - 5.2e-08 33.1 0.0 1.8e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EJS43259.1 - 1.1e-05 25.2 0.0 0.019 15.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EJS43259.1 - 0.00025 21.1 0.0 0.00091 19.4 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Corona_NS2A PF05213.7 EJS43259.1 - 0.037 13.3 0.0 0.09 12.0 0.0 1.6 1 0 0 1 1 1 0 Coronavirus NS2A protein Spuma_A9PTase PF03539.9 EJS43259.1 - 0.094 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Helicase_C PF00271.26 EJS43260.1 - 7.9e-20 70.5 0.1 2.4e-19 68.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EJS43260.1 - 4.3e-19 68.6 0.0 7e-18 64.6 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 EJS43260.1 - 3e-17 63.0 0.0 3e-17 63.0 0.0 4.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit STAT_int PF02865.12 EJS43260.1 - 0.0098 15.8 0.1 0.037 13.9 0.0 2.0 1 0 0 1 1 1 1 STAT protein, protein interaction domain AAA_22 PF13401.1 EJS43260.1 - 0.01 15.9 0.0 0.13 12.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain EF-hand_4 PF12763.2 EJS43261.1 - 1.7e-27 95.1 0.0 4.3e-14 52.1 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 EJS43261.1 - 5.5e-08 32.7 233.9 2.5e-06 27.4 11.5 9.2 4 2 6 10 10 10 5 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 EJS43261.1 - 1.1e-06 28.7 0.0 0.00078 19.5 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EJS43261.1 - 8e-06 24.7 0.0 0.0054 15.9 0.0 3.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EJS43261.1 - 0.00049 19.7 0.1 4.6 7.3 0.0 4.2 5 0 0 5 5 5 1 EF-hand domain MIS13 PF08202.6 EJS43262.1 - 1.3e-95 319.9 19.7 1.3e-95 319.9 13.6 1.7 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Cut8_C PF08559.5 EJS43263.1 - 6e-49 165.5 0.7 9.2e-49 164.9 0.5 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EJS43263.1 - 7.9e-15 54.3 4.1 1.5e-14 53.4 2.8 1.4 1 0 0 1 1 1 1 Cut8 dimerisation domain Pho88 PF10032.4 EJS43263.1 - 0.093 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphate transport (Pho88) WD40 PF00400.27 EJS43264.1 - 2.2e-07 30.4 11.1 0.0026 17.5 0.4 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EJS43264.1 - 1.6e-05 24.5 0.1 0.024 14.1 0.0 2.9 1 1 1 2 2 2 2 PQQ-like domain Apc4_WD40 PF12894.2 EJS43264.1 - 5.6e-05 22.5 0.0 0.0042 16.5 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain GATA PF00320.22 EJS43265.1 - 2.5e-13 49.1 2.6 3.8e-13 48.5 1.8 1.3 1 0 0 1 1 1 1 GATA zinc finger VWD PF00094.20 EJS43265.1 - 0.015 15.5 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type D domain bZIP_1 PF00170.16 EJS43266.1 - 8.6e-06 25.6 10.8 8.6e-06 25.6 7.5 2.2 1 1 1 2 2 2 1 bZIP transcription factor DUF641 PF04859.7 EJS43266.1 - 0.0014 18.3 6.1 0.0027 17.4 4.2 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Glutaredoxin2_C PF04399.8 EJS43266.1 - 0.0014 18.1 2.4 0.0026 17.3 1.6 1.4 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain Ribosomal_L20 PF00453.13 EJS43266.1 - 0.042 13.7 4.0 0.067 13.1 2.8 1.2 1 0 0 1 1 1 0 Ribosomal protein L20 RNA_pol_Rpc4 PF05132.9 EJS43266.1 - 0.25 11.3 1.5 0.68 9.9 1.0 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 bZIP_2 PF07716.10 EJS43266.1 - 0.27 11.0 13.7 0.23 11.2 7.0 2.5 2 1 0 2 2 2 0 Basic region leucine zipper Orbi_VP5 PF00901.12 EJS43266.1 - 0.46 8.6 6.2 0.65 8.1 4.3 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 APG6 PF04111.7 EJS43266.1 - 0.48 9.4 7.7 0.73 8.8 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 GvpL_GvpF PF06386.6 EJS43266.1 - 0.52 9.8 4.5 0.79 9.2 3.1 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF V_ATPase_I PF01496.14 EJS43266.1 - 0.97 7.2 3.7 1.1 6.9 2.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EJS43266.1 - 3 6.1 7.5 4.3 5.6 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EJS43266.1 - 7.4 6.1 10.4 12 5.4 7.2 1.3 1 0 0 1 1 1 0 IncA protein BAG PF02179.11 EJS43267.1 - 1.2e-18 66.9 3.0 1.7e-18 66.4 2.1 1.2 1 0 0 1 1 1 1 BAG domain Aa_trans PF01490.13 EJS43268.1 - 1.3e-134 448.7 14.9 1.5e-134 448.5 10.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2416 PF10315.4 EJS43269.1 - 1.9e-38 131.0 1.0 3.5e-38 130.1 0.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Glyco_transf_15 PF01793.11 EJS43270.1 - 7.6e-124 412.9 16.7 1.3e-123 412.2 11.6 1.3 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Sds3 PF08598.6 EJS43271.1 - 4e-67 225.7 8.6 6e-67 225.1 5.9 1.3 1 1 0 1 1 1 1 Sds3-like Tim44 PF04280.10 EJS43271.1 - 0.047 13.6 0.1 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Tim44-like domain zf-CCHC PF00098.18 EJS43272.1 - 1.1e-09 37.6 24.6 1.7e-05 24.5 1.6 4.9 6 0 0 6 6 6 3 Zinc knuckle POPLD PF08170.7 EJS43272.1 - 0.21 11.4 5.3 0.071 12.9 0.9 2.1 1 1 1 2 2 2 0 POPLD (NUC188) domain zf-CCHC_4 PF14392.1 EJS43272.1 - 1.7 8.3 34.2 0.32 10.6 0.4 5.4 4 1 1 5 5 5 0 Zinc knuckle DUF1689 PF07954.6 EJS43273.1 - 4.6e-58 195.3 0.3 6.3e-58 194.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) PC_rep PF01851.17 EJS43274.1 - 4.7e-44 146.2 23.1 2.4e-06 27.4 0.0 10.9 10 0 0 10 10 10 9 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EJS43274.1 - 3.5e-15 56.0 10.0 3.9e-13 49.5 0.1 4.7 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.17 EJS43274.1 - 1.1e-07 31.3 3.1 0.55 10.4 0.1 4.6 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 EJS43274.1 - 2.3e-07 31.1 7.6 0.041 14.3 0.1 5.6 4 2 2 6 6 5 2 HEAT-like repeat Apc3 PF12895.2 EJS43274.1 - 0.012 15.7 0.9 3.7 7.7 0.1 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 RICTOR_V PF14668.1 EJS43274.1 - 0.033 14.1 0.2 0.23 11.3 0.0 2.6 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 EJS43274.1 - 0.095 13.2 5.2 24 5.7 0.0 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat NARP1 PF12569.3 EJS43274.1 - 0.23 10.1 15.9 0.46 9.1 11.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.5 EJS43274.1 - 0.72 9.8 18.6 1.4 8.9 12.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.7 EJS43274.1 - 0.88 9.4 6.9 1.5 8.7 4.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family U79_P34 PF03064.11 EJS43274.1 - 2.9 7.3 12.0 4.7 6.6 8.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 2-Hacid_dh_C PF02826.14 EJS43275.1 - 2.1e-52 176.8 0.0 3e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EJS43275.1 - 9e-38 128.7 0.0 1.2e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EJS43275.1 - 4.1e-06 26.7 0.2 9.5e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EJS43275.1 - 0.00012 21.9 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acetyltransf_1 PF00583.19 EJS43275.1 - 0.0014 18.5 0.0 0.024 14.6 0.0 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) family ACT PF01842.20 EJS43275.1 - 0.0097 15.3 0.0 0.04 13.4 0.0 2.0 1 1 0 1 1 1 1 ACT domain HORMA PF02301.13 EJS43276.1 - 2.6e-47 161.0 1.4 2.6e-47 161.0 1.0 1.9 2 0 0 2 2 2 1 HORMA domain HGTP_anticodon2 PF12745.2 EJS43276.1 - 0.04 13.0 3.4 0.12 11.5 0.5 2.6 2 1 0 2 2 2 0 Anticodon binding domain of tRNAs PHD_2 PF13831.1 EJS43276.1 - 0.051 12.8 2.9 0.091 12.0 2.0 1.4 1 0 0 1 1 1 0 PHD-finger MAM33 PF02330.11 EJS43277.1 - 4.3e-72 242.1 7.4 5e-72 241.9 5.1 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein LCCL PF03815.14 EJS43278.1 - 3e-08 33.5 0.2 6.3e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 LCCL domain Ribonuc_red_lgC PF02867.10 EJS43279.1 - 2.8e-211 702.7 0.0 4.1e-211 702.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EJS43279.1 - 2.7e-23 81.5 0.0 9e-23 79.8 0.0 2.0 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EJS43279.1 - 1.4e-15 57.4 0.0 6.5e-15 55.3 0.0 2.3 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 EJS43279.1 - 0.046 11.8 0.0 0.07 11.1 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Fis1_TPR_C PF14853.1 EJS43280.1 - 7.8e-24 83.3 0.6 1.2e-23 82.6 0.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EJS43280.1 - 1.1e-13 50.1 0.0 1.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.1 EJS43280.1 - 0.089 13.1 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Ran_BP1 PF00638.13 EJS43281.1 - 4.2e-43 146.2 0.6 9.7e-43 145.1 0.4 1.6 1 0 0 1 1 1 1 RanBP1 domain Peptidase_S64 PF08192.6 EJS43281.1 - 1.3 7.2 11.0 1.6 6.9 7.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 GOLD_2 PF13897.1 EJS43281.1 - 7.8 6.7 9.3 0.69 10.1 2.0 2.4 1 1 0 2 2 2 0 Golgi-dynamics membrane-trafficking P16-Arc PF04699.9 EJS43282.1 - 3.7e-50 169.8 0.0 4.2e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) RolB_RolC PF02027.12 EJS43282.1 - 0.0088 15.2 0.7 0.026 13.6 0.1 1.9 1 1 1 2 2 2 1 RolB/RolC glucosidase family U1snRNP70_N PF12220.3 EJS43283.1 - 9.4e-24 83.5 2.8 1.8e-23 82.6 2.0 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EJS43283.1 - 8.6e-16 57.3 0.2 4.5e-15 55.0 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS43283.1 - 3.9e-11 42.7 0.1 1.2e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS43283.1 - 0.00016 21.4 0.1 0.00032 20.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3906 PF13046.1 EJS43283.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) DUF2578 PF10843.3 EJS43284.1 - 1.2e-66 224.1 14.2 1.3e-66 223.9 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) DIX PF00778.12 EJS43284.1 - 0.0012 18.4 0.8 0.0031 17.1 0.6 1.8 1 0 0 1 1 1 1 DIX domain COX7a PF02238.10 EJS43284.1 - 0.038 13.7 0.1 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Acetone_carb_G PF08882.6 EJS43284.1 - 0.045 13.7 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit Vhr1 PF04001.8 EJS43285.1 - 2.7e-51 171.4 3.7 7.7e-51 169.9 2.6 1.8 1 0 0 1 1 1 1 Transcription factor Vhr1 Codanin-1_C PF15296.1 EJS43285.1 - 0.21 11.4 0.1 0.21 11.4 0.0 2.2 3 0 0 3 3 3 0 Codanin-1 C-terminus Ribonuclease_3 PF00636.21 EJS43285.1 - 2.4 8.6 5.1 13 6.2 0.1 3.6 2 2 1 3 3 3 0 Ribonuclease III domain K_channel_TID PF07941.6 EJS43286.1 - 7.3 6.8 11.4 0.78 10.0 2.5 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain HAD_2 PF13419.1 EJS43287.1 - 8e-13 48.9 0.0 1.1e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EJS43287.1 - 6.4e-09 36.5 0.0 2.4e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EJS43287.1 - 2.1e-07 30.5 0.0 3.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EJS43287.1 - 0.0018 18.4 0.0 0.0025 18.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribonuc_L-PSP PF01042.16 EJS43288.1 - 9.4e-43 144.8 0.8 1.1e-42 144.6 0.5 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cyclin PF08613.6 EJS43289.1 - 4.9e-52 176.2 0.1 7.6e-52 175.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Steroid_dh PF02544.11 EJS43290.1 - 2.3e-09 37.2 7.8 4.7e-09 36.1 4.9 1.9 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase E1-E2_ATPase PF00122.15 EJS43291.1 - 1.2e-31 109.5 0.0 2.6e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EJS43291.1 - 9.9e-14 52.2 0.0 1.1e-12 48.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EJS43291.1 - 1.9e-10 41.1 0.1 6.1e-10 39.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EJS43291.1 - 4.9e-08 32.8 0.0 1.6e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EJS43291.1 - 0.0083 15.7 0.1 0.0083 15.7 0.1 3.0 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase PhaG_MnhG_YufB PF03334.9 EJS43291.1 - 0.28 11.2 5.8 8.2 6.5 0.0 3.1 3 0 0 3 3 3 0 Na+/H+ antiporter subunit EXS PF03124.9 EJS43292.1 - 6.2e-92 308.2 25.2 8.6e-92 307.8 17.5 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EJS43292.1 - 2.8e-39 135.5 0.1 5.2e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 SPX domain Adeno_E3B PF03376.9 EJS43292.1 - 0.12 12.2 4.4 0.52 10.2 3.1 2.0 1 0 0 1 1 1 0 Adenovirus E3B protein CBM_21 PF03370.8 EJS43293.1 - 4.4e-30 103.9 1.9 9.5e-30 102.8 1.3 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit DUF1589 PF07628.6 EJS43293.1 - 0.0075 16.1 0.1 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1589) ArfGap PF01412.13 EJS43294.1 - 2.5e-37 127.2 0.7 2.5e-37 127.2 0.5 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BCDHK_Adom3 PF10436.4 EJS43295.1 - 7.3e-28 97.1 0.3 1.3e-27 96.2 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EJS43295.1 - 1.3e-19 69.9 0.0 1.9e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EJS43295.1 - 6.6e-05 22.5 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EJS43295.1 - 0.058 13.1 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain BAR_2 PF10455.4 EJS43296.1 - 2.4e-92 308.9 10.4 2.4e-92 308.9 7.2 1.8 1 1 1 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EJS43296.1 - 6.5e-10 38.9 5.2 6.5e-10 38.9 3.6 2.2 2 1 0 2 2 2 1 BAR domain DUF3452 PF11934.3 EJS43296.1 - 0.017 14.4 0.1 0.017 14.4 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3452) TMF_TATA_bd PF12325.3 EJS43296.1 - 0.2 11.3 7.3 0.24 11.1 0.2 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.6 EJS43296.1 - 1 9.7 5.7 6.5 7.2 0.6 3.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal LKAAEAR PF15478.1 EJS43296.1 - 1.1 9.5 5.7 0.2 11.8 0.4 2.4 3 0 0 3 3 3 0 Family of unknown function with LKAAEAR motif Atg14 PF10186.4 EJS43296.1 - 3.6 6.4 12.4 1.3 7.8 2.8 2.4 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Apq12 PF12716.2 EJS43297.1 - 5.3e-06 26.0 8.9 5.3e-06 26.0 6.1 1.8 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis Metallophos PF00149.23 EJS43298.1 - 2.2e-40 138.2 4.9 2.2e-40 138.2 3.4 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Not3 PF04065.10 EJS43299.1 - 3.2e-90 301.4 29.0 3.2e-90 301.4 20.1 2.6 2 1 1 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EJS43299.1 - 2.6e-26 92.0 2.3 7.7e-26 90.5 0.1 3.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF912 PF06024.7 EJS43300.1 - 0.18 11.8 5.7 3.2 7.8 0.1 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pkinase PF00069.20 EJS43301.1 - 9.7e-54 182.2 5.2 4.2e-52 176.8 3.6 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43301.1 - 2.5e-18 66.0 1.0 1.5e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EJS43301.1 - 2.2e-05 24.2 0.1 8.1e-05 22.4 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EJS43301.1 - 0.015 14.8 0.1 0.015 14.8 0.1 2.3 3 0 0 3 3 3 0 Choline/ethanolamine kinase F_actin_cap_B PF01115.12 EJS43302.1 - 4e-103 343.8 0.2 4.5e-103 343.6 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF3212 PF11486.3 EJS43302.1 - 0.091 12.5 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) cNMP_binding PF00027.24 EJS43303.1 - 1.3e-44 149.8 0.0 7.8e-23 80.1 0.0 2.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EJS43303.1 - 5.6e-14 51.2 1.8 1.7e-13 49.7 1.3 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit YwhD PF08741.5 EJS43303.1 - 0.083 12.2 0.1 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 YwhD family DUF3973 PF13119.1 EJS43303.1 - 0.16 11.9 0.1 0.38 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) ATP-synt_DE_N PF02823.11 EJS43303.1 - 0.24 11.1 0.6 14 5.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain RINGv PF12906.2 EJS43304.1 - 1.9e-15 56.6 5.0 3.3e-15 55.8 3.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EJS43304.1 - 0.012 15.4 4.9 0.024 14.4 3.4 1.6 1 0 0 1 1 1 0 Ring finger domain MMgT PF10270.4 EJS43305.1 - 1.5e-27 96.0 0.0 1.8e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter STAG PF08514.6 EJS43306.1 - 1.9e-08 34.0 2.3 1.9e-08 34.0 1.6 2.7 3 0 0 3 3 3 1 STAG domain Zip PF02535.17 EJS43308.1 - 1.9e-58 197.9 17.4 1.5e-56 191.7 12.0 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3054 PF11255.3 EJS43308.1 - 0.059 13.1 0.9 0.28 11.0 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3054) Gly-zipper_OmpA PF13436.1 EJS43308.1 - 0.39 10.3 1.5 1.1 8.9 1.1 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bax1-I PF01027.15 EJS43308.1 - 9.7 5.7 17.8 0.019 14.5 1.5 2.8 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Tim44 PF04280.10 EJS43309.1 - 6.2e-35 120.3 0.1 1.6e-34 118.9 0.1 1.8 1 0 0 1 1 1 1 Tim44-like domain CCDC32 PF14989.1 EJS43309.1 - 0.012 15.3 0.5 0.49 10.2 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing 32 RNA_pol_A_bac PF01000.21 EJS43310.1 - 3.2e-31 107.7 0.1 6.5e-31 106.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EJS43310.1 - 1.2e-14 53.1 0.0 1.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.1 EJS43312.1 - 4.9e-18 65.5 0.3 6.9e-18 65.0 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like CLTH PF10607.4 EJS43313.1 - 3.6e-31 107.8 19.9 6.6e-31 106.9 3.8 3.2 3 0 0 3 3 3 2 CTLH/CRA C-terminal to LisH motif domain DUF4559 PF15112.1 EJS43313.1 - 0.0015 17.8 5.8 0.0031 16.7 4.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) U-box PF04564.10 EJS43313.1 - 0.017 15.0 0.0 0.066 13.1 0.0 2.1 1 0 0 1 1 1 0 U-box domain DUF3922 PF13059.1 EJS43313.1 - 0.019 15.1 0.2 0.066 13.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) DUF4239 PF14023.1 EJS43313.1 - 0.16 11.2 1.6 0.28 10.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF2431 PF10354.4 EJS43314.1 - 4.3e-56 189.4 1.4 8.2e-56 188.5 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Pkinase PF00069.20 EJS43315.1 - 3e-36 124.9 0.0 4.8e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43315.1 - 1.1e-30 106.5 0.0 3.5e-30 104.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43315.1 - 5.9e-05 22.1 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EJS43315.1 - 0.14 11.8 0.0 0.45 10.2 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Iso_dh PF00180.15 EJS43316.1 - 5.7e-114 380.6 0.0 6.8e-114 380.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MRP-S25 PF13741.1 EJS43317.1 - 1.5e-90 302.7 1.2 1.8e-90 302.4 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EJS43317.1 - 0.0011 18.8 0.3 0.046 13.6 0.0 2.5 1 1 0 2 2 2 1 Mitochondrial ribosomal protein S23 DUF1253 PF06862.7 EJS43318.1 - 1e-162 541.5 12.7 1.4e-162 541.1 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) ICE2 PF08426.5 EJS43319.1 - 3.4e-174 579.3 22.6 3.9e-174 579.0 15.7 1.0 1 0 0 1 1 1 1 ICE2 Ank_2 PF12796.2 EJS43321.1 - 1e-48 163.5 1.6 4.5e-23 81.4 0.1 3.7 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EJS43321.1 - 9.2e-36 119.9 0.7 3.7e-10 39.0 0.1 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EJS43321.1 - 5.3e-30 102.7 0.0 3.1e-07 30.4 0.0 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EJS43321.1 - 1.6e-27 95.3 0.0 7.5e-11 42.2 0.0 4.6 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EJS43321.1 - 7e-26 87.7 0.0 1.7e-08 33.9 0.1 4.9 4 0 0 4 4 4 4 Ankyrin repeat Imm45 PF15603.1 EJS43321.1 - 0.011 15.8 2.6 0.21 11.7 0.0 3.5 3 0 0 3 3 3 0 Immunity protein 45 DUF1110 PF06533.7 EJS43321.1 - 0.042 13.6 0.0 2.9 7.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1110) Sec23_trunk PF04811.10 EJS43322.1 - 9.6e-75 251.0 0.0 2.3e-74 249.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EJS43322.1 - 9.2e-25 86.0 1.0 1.7e-24 85.1 0.2 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EJS43322.1 - 3.1e-18 65.0 5.7 5.5e-18 64.2 4.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EJS43322.1 - 2.1e-14 53.8 0.2 2.1e-14 53.8 0.2 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EJS43322.1 - 4.4e-11 42.3 0.0 1.1e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat PAT1 PF09770.4 EJS43322.1 - 3.7 5.6 36.1 5 5.2 25.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 6PF2K PF01591.13 EJS43323.1 - 3.7e-86 287.7 0.0 6.7e-86 286.9 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EJS43323.1 - 1.6e-30 106.3 0.0 3.1e-29 102.1 0.0 2.5 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EJS43323.1 - 1.2e-09 38.1 0.0 5.4e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EJS43323.1 - 8e-07 29.9 0.1 3.4e-06 27.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EJS43323.1 - 0.0029 17.9 0.0 0.017 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EJS43323.1 - 0.013 14.6 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 EJS43323.1 - 0.018 15.0 0.1 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.15 EJS43323.1 - 0.061 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase PH PF00169.24 EJS43324.1 - 1.8e-15 56.9 0.4 4.5e-15 55.7 0.3 1.7 1 0 0 1 1 1 1 PH domain DPM2 PF07297.7 EJS43325.1 - 2.8e-08 33.9 1.0 3.6e-08 33.5 0.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EJS43325.1 - 8 6.1 8.5 15 5.2 5.9 1.5 1 1 0 1 1 1 0 PIG-P Glyco_hydro_32N PF00251.15 EJS43327.1 - 4.9e-89 298.7 13.1 7.9e-89 298.0 9.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EJS43327.1 - 5.5e-09 36.2 0.3 1.6e-08 34.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Rio2_N PF09202.6 EJS43328.1 - 0.0031 17.5 0.2 5.4 7.1 0.0 3.0 3 0 0 3 3 3 2 Rio2, N-terminal Dsh_C PF12316.3 EJS43328.1 - 0.4 10.7 8.8 0.58 10.2 6.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Thiolase_N PF00108.18 EJS43329.1 - 3.4e-87 291.7 0.0 4.6e-87 291.3 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EJS43329.1 - 1.8e-50 169.4 0.3 3.2e-50 168.6 0.2 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EJS43329.1 - 0.0045 16.5 0.9 0.0078 15.7 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain FH2 PF02181.18 EJS43330.1 - 7.3e-73 245.5 17.6 7.3e-73 245.5 12.2 2.5 2 0 0 2 2 2 2 Formin Homology 2 Domain Hpt PF01627.18 EJS43330.1 - 0.12 12.3 0.0 0.48 10.4 0.0 2.0 1 0 0 1 1 1 0 Hpt domain Cytochrom_B_N_2 PF13631.1 EJS43330.1 - 0.16 11.7 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Coa1 PF08695.5 EJS43331.1 - 9.7e-38 128.2 0.0 1.4e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 UCH PF00443.24 EJS43332.1 - 8.7e-63 211.9 3.5 1.6e-62 211.0 2.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EJS43332.1 - 6.1e-28 98.1 3.1 7.4e-28 97.8 1.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EJS43332.1 - 0.012 15.9 0.0 0.033 14.5 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain Jiraiya PF15038.1 EJS43332.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Jiraiya DAO PF01266.19 EJS43333.1 - 4.4e-55 187.0 0.0 6.2e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EJS43333.1 - 3.8e-13 49.0 2.5 2.2e-07 30.0 0.7 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EJS43333.1 - 2e-11 43.6 0.1 3e-08 33.1 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EJS43333.1 - 2.4e-06 27.5 0.4 0.00013 21.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EJS43333.1 - 4.2e-06 25.8 1.8 0.0034 16.3 0.5 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EJS43333.1 - 3.8e-05 22.8 0.3 0.02 13.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 EJS43333.1 - 0.00017 20.2 0.7 0.00029 19.4 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EJS43333.1 - 0.00019 21.3 0.7 0.00067 19.6 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EJS43333.1 - 0.00024 20.2 0.8 0.0033 16.5 0.5 2.2 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EJS43333.1 - 0.0022 16.9 0.9 0.061 12.2 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GMC_oxred_N PF00732.14 EJS43333.1 - 0.0077 15.4 0.1 0.028 13.5 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase 3HCDH_N PF02737.13 EJS43333.1 - 0.033 13.8 1.3 0.15 11.7 0.9 2.1 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EJS43333.1 - 0.066 13.6 0.4 0.17 12.3 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Daxx PF03344.10 EJS43334.1 - 0.16 10.4 13.2 0.22 9.9 9.2 1.3 1 0 0 1 1 1 0 Daxx Family COPI_C PF06957.6 EJS43334.1 - 0.27 9.7 3.5 0.35 9.3 2.4 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus CAF1A PF12253.3 EJS43334.1 - 0.63 10.1 15.6 1.9 8.6 10.8 1.9 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A RRN3 PF05327.6 EJS43334.1 - 2 6.4 5.1 2.7 5.9 3.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.8 EJS43334.1 - 7.3 6.1 11.2 69 2.9 8.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.7 EJS43334.1 - 7.6 4.3 17.9 1.2e+02 0.3 13.7 1.7 2 0 0 2 2 2 0 Nop14-like family PTPA PF03095.10 EJS43335.1 - 9.5e-108 359.8 0.0 1.1e-107 359.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PIN_4 PF13638.1 EJS43337.1 - 6.1e-10 39.3 2.6 1.2e-09 38.3 1.8 1.5 1 0 0 1 1 1 1 PIN domain MHC_II_alpha PF00993.15 EJS43337.1 - 0.002 17.6 0.2 0.093 12.3 0.0 3.0 3 0 0 3 3 3 1 Class II histocompatibility antigen, alpha domain zf-primase PF09329.6 EJS43338.1 - 1.2e-13 50.4 3.9 3e-13 49.1 2.7 1.7 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 EJS43338.1 - 0.048 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain TPR_MLP1_2 PF07926.7 EJS43339.1 - 6e-13 48.6 23.1 6e-13 48.6 16.0 15.4 4 3 7 13 13 13 3 TPR/MLP1/MLP2-like protein HATPase_c PF02518.21 EJS43340.1 - 1.8e-27 95.2 6.7 2.1e-27 95.0 1.9 2.9 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EJS43340.1 - 3e-27 94.8 0.0 7.2e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EJS43340.1 - 8.5e-11 41.6 0.1 3e-10 39.9 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EJS43340.1 - 0.03 14.5 11.8 0.24 11.5 0.3 3.3 4 0 0 4 4 4 0 HAMP domain Pantoate_ligase PF02569.10 EJS43342.1 - 6.6e-116 385.9 0.0 7.4e-116 385.8 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase FAD_syn PF06574.7 EJS43342.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase Helicase_C_3 PF13625.1 EJS43343.1 - 1.9e-25 89.0 0.0 6.3e-25 87.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EJS43343.1 - 4.2e-14 52.7 0.0 9.7e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EJS43343.1 - 4.3e-12 45.4 0.1 6.8e-12 44.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EJS43343.1 - 1.5e-10 40.8 0.0 3.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EJS43343.1 - 2.2e-07 30.5 0.0 4.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.1 EJS43343.1 - 0.035 13.4 0.0 0.096 11.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein AAA_34 PF13872.1 EJS43343.1 - 0.057 12.1 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Cpn60_TCP1 PF00118.19 EJS43344.1 - 4.1e-136 454.4 12.2 4.9e-136 454.1 8.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transposase_23 PF03017.9 EJS43344.1 - 0.01 15.3 0.0 0.036 13.5 0.0 1.9 1 0 0 1 1 1 0 TNP1/EN/SPM transposase SKG6 PF08693.5 EJS43345.1 - 4.3e-15 54.7 1.0 1.2e-14 53.2 0.7 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain He_PIG PF05345.7 EJS43345.1 - 1.1e-11 44.5 3.2 4.7e-05 23.3 0.0 4.6 4 0 0 4 4 4 2 Putative Ig domain Rifin_STEVOR PF02009.11 EJS43345.1 - 4.2e-06 26.6 0.4 7.1e-06 25.8 0.3 1.2 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 EJS43345.1 - 4e-05 23.3 1.8 0.00015 21.4 1.3 2.0 1 0 0 1 1 1 1 TMEM154 protein family Adeno_E3_CR2 PF02439.10 EJS43345.1 - 0.00015 21.2 3.2 0.00028 20.3 2.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Amnionless PF14828.1 EJS43345.1 - 0.00035 19.1 0.1 0.00071 18.1 0.1 1.4 1 0 0 1 1 1 1 Amnionless DUF912 PF06024.7 EJS43345.1 - 0.02 14.9 0.3 0.02 14.9 0.2 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mid2 PF04478.7 EJS43345.1 - 0.17 11.3 9.7 0.1 11.9 4.7 2.1 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Podoplanin PF05808.6 EJS43345.1 - 0.25 10.9 11.7 0.86 9.1 8.1 1.9 1 1 0 1 1 1 0 Podoplanin Mucin PF01456.12 EJS43345.1 - 2.6 7.7 26.0 0.27 10.9 14.2 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein HORMA PF02301.13 EJS43346.1 - 2.8e-20 72.6 2.7 3.6e-20 72.3 1.9 1.1 1 0 0 1 1 1 1 HORMA domain Tropomyosin_1 PF12718.2 EJS43347.1 - 3.2e-43 147.0 42.8 3.8e-43 146.7 29.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EJS43347.1 - 3.4e-09 36.1 39.7 3.6e-05 22.9 11.3 2.1 1 1 1 2 2 2 2 Tropomyosin TMF_DNA_bd PF12329.3 EJS43347.1 - 0.00014 21.6 45.9 0.0013 18.4 12.9 3.2 2 1 1 3 3 3 2 TATA element modulatory factor 1 DNA binding WXG100 PF06013.7 EJS43347.1 - 0.00034 20.5 15.3 0.13 12.2 0.0 3.8 2 1 0 2 2 2 1 Proteins of 100 residues with WXG TelA PF05816.6 EJS43347.1 - 0.00049 18.9 2.6 0.00049 18.9 1.8 2.1 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) ADIP PF11559.3 EJS43347.1 - 0.00057 19.8 35.5 0.015 15.1 9.6 2.5 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EJS43347.1 - 0.00098 18.2 42.2 0.02 13.9 13.0 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 ERM PF00769.14 EJS43347.1 - 0.0014 18.2 22.8 0.0014 18.2 15.8 2.0 1 1 1 2 2 2 1 Ezrin/radixin/moesin family KLRAQ PF10205.4 EJS43347.1 - 0.0021 18.0 25.4 0.0036 17.3 8.5 2.2 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Seryl_tRNA_N PF02403.17 EJS43347.1 - 0.0027 17.7 32.4 0.025 14.6 3.3 2.8 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Filament PF00038.16 EJS43347.1 - 0.0034 16.9 32.9 0.016 14.6 10.2 2.0 1 1 1 2 2 2 1 Intermediate filament protein GAS PF13851.1 EJS43347.1 - 0.0039 16.4 37.9 0.085 12.0 17.8 2.6 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EJS43347.1 - 0.0076 16.1 43.1 0.16 11.8 7.6 2.8 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps5 PF09325.5 EJS43347.1 - 0.0078 15.4 7.1 0.0078 15.4 4.9 2.9 1 1 2 3 3 3 1 Vps5 C terminal like Myosin_tail_1 PF01576.14 EJS43347.1 - 0.0088 13.8 38.9 0.014 13.1 26.9 1.3 1 1 0 1 1 1 1 Myosin tail BLOC1_2 PF10046.4 EJS43347.1 - 0.0089 16.1 31.9 0.21 11.7 6.7 3.3 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 EJS43347.1 - 0.0091 15.7 23.5 0.018 14.8 7.8 2.4 1 1 1 2 2 2 1 Laminin Domain II AAA_27 PF13514.1 EJS43347.1 - 0.0099 13.6 29.5 0.012 13.3 20.5 1.1 1 0 0 1 1 1 1 AAA domain ATG16 PF08614.6 EJS43347.1 - 0.013 15.3 34.1 0.28 10.9 12.6 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.6 EJS43347.1 - 0.015 15.2 26.4 1.1 9.2 2.3 4.2 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 EJS43347.1 - 0.016 14.4 8.3 0.076 12.1 0.9 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein EzrA PF06160.7 EJS43347.1 - 0.019 13.1 28.8 0.047 11.8 4.1 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_13 PF13166.1 EJS43347.1 - 0.021 13.3 31.0 0.026 13.0 21.5 1.1 1 0 0 1 1 1 0 AAA domain MbeD_MobD PF04899.7 EJS43347.1 - 0.022 14.6 2.2 0.022 14.6 1.5 3.1 1 1 1 3 3 3 0 MbeD/MobD like DUF3584 PF12128.3 EJS43347.1 - 0.025 11.9 32.4 0.027 11.8 22.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mnd1 PF03962.10 EJS43347.1 - 0.034 13.7 35.3 0.36 10.4 11.7 2.1 1 1 1 2 2 2 0 Mnd1 family Cortex-I_coil PF09304.5 EJS43347.1 - 0.041 13.9 33.9 0.31 11.0 9.3 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil Nudix_N PF12535.3 EJS43347.1 - 0.078 12.4 1.0 0.25 10.8 0.7 1.9 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal TBPIP PF07106.8 EJS43347.1 - 0.083 12.4 36.2 1.2 8.7 11.2 2.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IFT57 PF10498.4 EJS43347.1 - 0.087 11.5 30.2 0.046 12.4 16.2 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 IncA PF04156.9 EJS43347.1 - 0.093 12.3 40.9 0.55 9.7 19.3 2.2 1 1 1 2 2 2 0 IncA protein Lectin_N PF03954.9 EJS43347.1 - 0.095 12.1 11.9 0.034 13.5 4.4 2.3 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Nup54 PF13874.1 EJS43347.1 - 0.11 12.1 22.7 0.079 12.6 6.7 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Fib_alpha PF08702.5 EJS43347.1 - 0.12 12.5 23.2 0.38 10.8 5.5 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Taxilin PF09728.4 EJS43347.1 - 0.13 11.3 35.9 0.017 14.2 8.5 2.4 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Uds1 PF15456.1 EJS43347.1 - 0.16 11.9 29.6 0.17 11.8 8.1 3.0 1 1 1 2 2 2 0 Up-regulated During Septation Mod_r PF07200.8 EJS43347.1 - 0.17 11.7 33.8 0.46 10.3 16.8 2.9 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.7 EJS43347.1 - 0.2 11.9 16.9 13 6.0 2.1 4.0 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 EJS43347.1 - 0.23 10.3 29.1 0.18 10.7 8.3 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EJS43347.1 - 0.24 10.0 34.5 0.27 9.8 12.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.6 EJS43347.1 - 0.25 9.7 30.2 0.63 8.4 7.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Ax_dynein_light PF10211.4 EJS43347.1 - 0.3 10.9 38.1 0.44 10.3 7.9 3.1 1 1 3 4 4 4 0 Axonemal dynein light chain DASH_Hsk3 PF08227.6 EJS43347.1 - 0.39 10.9 7.5 0.63 10.2 0.8 2.7 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like PEPcase PF00311.12 EJS43347.1 - 0.41 8.4 12.5 0.41 8.4 8.7 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF4407 PF14362.1 EJS43347.1 - 0.45 9.4 18.6 0.63 8.9 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.3 EJS43347.1 - 0.45 9.7 29.5 0.58 9.3 6.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) MIS13 PF08202.6 EJS43347.1 - 0.57 9.1 31.1 4.8 6.1 7.8 2.2 1 1 1 2 2 2 0 Mis12-Mtw1 protein family DUF4201 PF13870.1 EJS43347.1 - 0.57 9.5 34.4 4.2 6.7 15.5 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) WEMBL PF05701.6 EJS43347.1 - 0.6 8.5 35.5 0.081 11.3 10.4 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF972 PF06156.8 EJS43347.1 - 0.61 10.4 32.3 4.3 7.7 11.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Hormone_1 PF00103.15 EJS43347.1 - 0.61 9.3 15.4 0.13 11.6 5.6 2.3 1 1 2 3 3 3 0 Somatotropin hormone family HAP1_N PF04849.8 EJS43347.1 - 0.79 8.6 35.4 0.94 8.3 24.5 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region TPR_MLP1_2 PF07926.7 EJS43347.1 - 0.8 9.4 41.3 0.45 10.2 12.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.6 EJS43347.1 - 1 9.8 26.6 2.2 8.7 6.4 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DivIC PF04977.10 EJS43347.1 - 1.2 8.7 38.6 0.066 12.7 5.7 4.1 1 1 3 4 4 4 0 Septum formation initiator Lebercilin PF15619.1 EJS43347.1 - 1.2 8.5 36.3 19 4.6 25.1 2.2 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF2802 PF10975.3 EJS43347.1 - 1.2 8.9 17.0 12 5.7 0.5 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF2802) BBP1_C PF15272.1 EJS43347.1 - 1.2 8.6 32.8 2.8 7.4 3.1 3.2 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal GOLGA2L5 PF15070.1 EJS43347.1 - 1.3 7.3 28.5 1.7 7.0 19.8 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Rootletin PF15035.1 EJS43347.1 - 1.3 8.9 36.8 5.1 7.0 15.4 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF724 PF05266.9 EJS43347.1 - 1.4 8.5 33.1 3.5 7.2 10.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 EJS43347.1 - 1.4 7.0 28.2 2.6 6.2 13.8 1.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.16 EJS43347.1 - 1.5 8.8 38.9 6.3 6.8 8.6 4.9 1 1 4 5 5 5 0 bZIP transcription factor FliD_C PF07195.7 EJS43347.1 - 1.7 7.9 23.5 6.2 6.0 0.3 3.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Cast PF10174.4 EJS43347.1 - 1.7 6.5 37.2 32 2.3 25.7 1.9 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone AATF-Che1 PF13339.1 EJS43347.1 - 1.8 8.7 25.8 4.5 7.4 0.5 2.7 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Prefoldin_2 PF01920.15 EJS43347.1 - 1.8 8.3 44.0 6.2 6.6 3.0 4.2 1 1 3 4 4 4 0 Prefoldin subunit DUF1664 PF07889.7 EJS43347.1 - 1.9 8.3 18.7 5.6 6.7 4.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FH2 PF02181.18 EJS43347.1 - 1.9 7.2 23.3 0.68 8.7 5.4 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain FemAB PF02388.11 EJS43347.1 - 2 7.0 26.0 0.21 10.2 5.7 2.1 1 1 1 2 2 2 0 FemAB family DUF4200 PF13863.1 EJS43347.1 - 2 8.3 42.0 14 5.6 13.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.3 EJS43347.1 - 2 8.1 38.6 0.67 9.6 13.8 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FliJ PF02050.11 EJS43347.1 - 2.1 8.4 32.3 2.1 8.3 11.6 3.0 1 1 1 2 2 2 0 Flagellar FliJ protein MCPsignal PF00015.16 EJS43347.1 - 2.1 7.8 11.4 1.5 8.3 5.8 1.8 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FlaF PF07309.6 EJS43347.1 - 2.2 8.2 11.9 1.3 8.8 2.3 2.3 2 0 0 2 2 2 0 Flagellar protein FlaF Sec2p PF06428.6 EJS43347.1 - 2.3 8.0 33.4 0.28 11.0 12.3 3.3 1 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p TFR_dimer PF04253.10 EJS43347.1 - 2.9 7.4 11.0 36 3.9 4.2 3.2 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain T2SM PF04612.7 EJS43347.1 - 3 7.6 15.8 5.2 6.8 2.6 3.2 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M DUF869 PF05911.6 EJS43347.1 - 3.3 5.8 36.0 0.58 8.3 18.6 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DivIVA PF05103.8 EJS43347.1 - 3.6 7.6 34.8 2.5 8.1 2.9 3.4 1 1 2 3 3 3 0 DivIVA protein PRK PF00485.13 EJS43347.1 - 3.7 7.0 6.7 2.1 7.8 3.2 1.6 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Tweety PF04906.8 EJS43347.1 - 4.1 5.6 7.8 5.7 5.2 4.2 2.0 1 1 2 3 3 3 0 Tweety DUF342 PF03961.8 EJS43347.1 - 4.9 5.4 32.4 3.8 5.8 10.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Spc24 PF08286.6 EJS43347.1 - 5.7 6.6 39.2 4.7 6.9 4.1 4.0 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 Snapin_Pallidin PF14712.1 EJS43347.1 - 6.6 7.1 24.1 5.6 7.3 9.6 3.2 1 1 2 3 3 3 0 Snapin/Pallidin Noelin-1 PF12308.3 EJS43347.1 - 7.3 6.4 10.6 1.1 9.0 3.0 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein Kinetocho_Slk19 PF12709.2 EJS43347.1 - 8.1 6.6 35.6 0.8 9.8 2.2 4.1 1 1 3 4 4 4 0 Central kinetochore-associated DUF4613 PF15390.1 EJS43347.1 - 8.3 4.4 13.9 8.6 4.4 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PspA_IM30 PF04012.7 EJS43347.1 - 8.6 5.6 28.9 14 5.0 7.7 3.0 1 1 1 2 2 2 0 PspA/IM30 family bZIP_2 PF07716.10 EJS43347.1 - 8.9 6.2 33.4 0.088 12.6 2.4 4.6 3 1 2 5 5 5 0 Basic region leucine zipper Sec20 PF03908.8 EJS43347.1 - 9.2 6.0 13.4 3.6 7.3 2.4 3.2 1 1 2 3 3 3 0 Sec20 DUF3573 PF12097.3 EJS43347.1 - 9.2 4.7 9.5 11 4.4 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4559 PF15112.1 EJS43347.1 - 9.2 5.3 25.6 2.2 7.3 14.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Peptidase_M1 PF01433.15 EJS43348.1 - 1.2e-107 360.4 3.1 1.9e-107 359.7 2.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EJS43348.1 - 2.6e-69 233.9 0.0 4.3e-69 233.2 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EJS43348.1 - 9e-15 54.8 0.1 1.7e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily PBP_like PF12727.2 EJS43349.1 - 0.028 13.3 0.3 0.049 12.5 0.2 1.4 1 0 0 1 1 1 0 PBP superfamily domain IFT20 PF14931.1 EJS43349.1 - 0.26 11.2 4.9 0.14 12.0 1.1 2.4 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Syntaxin_2 PF14523.1 EJS43349.1 - 1.7 8.7 13.8 1 9.4 0.5 3.1 4 0 0 4 4 4 0 Syntaxin-like protein Fungal_trans PF04082.13 EJS43351.1 - 4.8e-38 130.5 2.5 4.8e-38 130.5 1.7 2.7 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS43351.1 - 5.8e-11 42.1 12.8 9.8e-11 41.3 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SMC_hinge PF06470.8 EJS43351.1 - 0.21 11.5 5.3 0.26 11.2 0.0 3.1 3 0 0 3 3 3 0 SMC proteins Flexible Hinge Domain MOR2-PAG1_N PF14222.1 EJS43352.1 - 1.1e-185 618.5 11.3 2.7e-185 617.2 7.8 1.8 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EJS43352.1 - 5.2e-97 324.6 1.2 5.2e-97 324.6 0.8 4.4 5 0 0 5 5 5 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EJS43352.1 - 2.2e-21 75.2 18.9 5.4e-11 40.8 0.4 3.8 3 1 0 3 3 3 3 Cell morphogenesis central region Suc_Fer-like PF06999.7 EJS43352.1 - 0.32 10.9 3.0 0.74 9.7 0.0 2.7 2 1 0 2 2 2 0 Sucrase/ferredoxin-like MMS19_C PF12460.3 EJS43353.1 - 9.3e-93 311.1 24.9 9.3e-93 311.1 17.2 3.7 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EJS43353.1 - 4.1e-90 301.6 23.3 5.1e-88 294.7 5.2 4.2 4 1 0 4 4 4 3 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.17 EJS43353.1 - 4.3e-06 26.3 0.5 0.021 14.8 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EJS43353.1 - 4.7e-06 26.7 0.0 0.00029 21.0 0.0 3.6 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 EJS43353.1 - 0.0019 18.6 1.1 0.58 10.7 0.0 4.4 5 1 1 6 6 6 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EJS43353.1 - 0.015 15.7 4.4 0.42 11.0 0.0 4.6 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 EJS43353.1 - 0.52 10.3 6.5 13 5.8 0.0 5.0 6 0 0 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation DUF342 PF03961.8 EJS43354.1 - 0.3 9.4 8.9 0.34 9.2 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SpoU_sub_bind PF08032.7 EJS43354.1 - 1.2 9.3 5.1 1.3 9.2 2.4 1.9 1 1 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Transket_pyr PF02779.19 EJS43355.1 - 2e-65 219.5 0.0 3.9e-65 218.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EJS43355.1 - 2e-55 187.6 0.0 2.6e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component LuxE PF04443.7 EJS43355.1 - 0.099 11.3 0.6 0.17 10.5 0.4 1.3 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE adh_short PF00106.20 EJS43356.1 - 3.6e-29 101.8 0.0 5.1e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EJS43356.1 - 6.6e-14 52.2 0.0 9.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EJS43356.1 - 5.3e-07 29.4 0.0 7.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EJS43356.1 - 1.2e-06 28.6 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EJS43356.1 - 2.6e-06 27.0 0.0 1.1e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EJS43356.1 - 0.00025 20.0 0.0 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.5 EJS43356.1 - 0.0011 18.1 0.0 1.5 7.9 0.0 2.9 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) Saccharop_dh PF03435.13 EJS43356.1 - 0.0017 17.3 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EJS43356.1 - 0.0051 16.0 0.0 0.009 15.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EJS43356.1 - 0.035 12.8 0.0 0.05 12.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EJS43356.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Myb_DNA-bind_4 PF13837.1 EJS43358.1 - 1.7e-05 24.8 2.8 1.7e-05 24.8 2.0 3.4 3 2 0 3 3 3 1 Myb/SANT-like DNA-binding domain Ras PF00071.17 EJS43359.1 - 3.4e-59 198.8 0.0 4.1e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS43359.1 - 9e-16 58.4 0.0 1.2e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS43359.1 - 1.4e-09 37.4 0.0 2e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EJS43359.1 - 0.00059 19.0 0.0 0.00072 18.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EJS43359.1 - 0.0016 17.2 0.0 0.0018 17.0 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EJS43359.1 - 0.0021 17.9 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EJS43359.1 - 0.0029 16.8 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EJS43359.1 - 0.031 13.9 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EJS43359.1 - 0.051 13.8 0.0 0.082 13.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Raptor_N PF14538.1 EJS43360.1 - 3.5e-65 218.5 0.0 3.5e-65 218.5 0.0 2.9 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 EJS43360.1 - 1.8e-07 30.6 0.6 0.0054 16.7 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat BBS2_Mid PF14783.1 EJS43360.1 - 4.2e-07 29.7 0.3 0.00014 21.6 0.0 3.1 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 EJS43360.1 - 2.5e-05 23.9 3.6 2 8.4 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT_2 PF13646.1 EJS43360.1 - 0.00012 22.2 0.0 0.0032 17.6 0.0 2.8 3 0 0 3 3 3 1 HEAT repeats Elong_Iki1 PF10483.4 EJS43361.1 - 2.5e-90 302.6 0.3 2.9e-90 302.4 0.2 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Pept_tRNA_hydro PF01195.14 EJS43362.1 - 8.2e-41 139.5 0.0 9.8e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase SQS_PSY PF00494.14 EJS43363.1 - 8.4e-38 130.1 0.0 1.1e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Ctf8 PF09696.5 EJS43364.1 - 3.7e-30 104.2 0.1 5.6e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Ctf8 NAC PF01849.13 EJS43365.1 - 6.5e-20 70.4 1.3 3.2e-19 68.2 0.1 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EJS43365.1 - 7.1e-06 25.6 2.7 1.2e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EJS43365.1 - 0.00011 21.6 0.3 0.00032 20.1 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain TMF_DNA_bd PF12329.3 EJS43365.1 - 0.32 10.8 0.1 0.32 10.8 0.1 3.3 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding MDM31_MDM32 PF08118.6 EJS43366.1 - 6.7e-266 882.5 8.3 7.7e-266 882.3 5.7 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Utp12 PF04003.7 EJS43368.1 - 0.00089 19.1 0.4 0.0018 18.1 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family PD40 PF07676.7 EJS43368.1 - 0.0035 16.9 0.7 4.5 7.0 0.1 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DUF4565 PF15127.1 EJS43368.1 - 0.036 14.3 2.8 0.13 12.6 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4565) Atrophin-1 PF03154.10 EJS43368.1 - 6.7 4.7 7.0 9.6 4.2 4.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family Chalcone PF02431.10 EJS43369.1 - 1.7e-43 148.3 0.0 2.1e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase VWA_2 PF13519.1 EJS43370.1 - 5.6e-09 36.3 0.0 8.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EJS43370.1 - 1.2e-05 24.9 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EJS43370.1 - 0.023 14.2 1.5 0.074 12.6 1.1 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif RE_R_Pab1 PF09522.5 EJS43370.1 - 0.081 12.8 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease Metallophos PF00149.23 EJS43371.1 - 1.3e-14 54.1 0.3 2.1e-14 53.4 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_47 PF01532.15 EJS43372.1 - 9.8e-116 387.0 0.0 1.2e-115 386.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Aminotran_1_2 PF00155.16 EJS43373.1 - 3e-15 56.0 0.0 3.9e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Carbpep_Y_N PF05388.6 EJS43374.1 - 0.0077 16.3 0.0 0.019 15.0 0.0 1.6 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide Inhibitor_I9 PF05922.11 EJS43374.1 - 0.017 15.6 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 Phage_C PF12025.3 EJS43374.1 - 0.034 14.0 0.0 0.061 13.2 0.0 1.5 1 1 0 1 1 1 0 Phage protein C Asparaginase PF00710.15 EJS43375.1 - 2.1e-27 95.8 2.0 3.2e-27 95.2 1.4 1.2 1 0 0 1 1 1 1 Asparaginase Chs3p PF12271.3 EJS43376.1 - 1.5e-97 326.1 22.9 5.1e-97 324.3 15.9 1.6 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit DUF2583 PF10762.4 EJS43376.1 - 3.7 7.7 7.9 1.8 8.7 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) DUF605 PF04652.11 EJS43377.1 - 0.28 10.5 25.7 0.31 10.3 17.8 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EJS43377.1 - 7.9 6.2 12.0 11 5.8 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_RNApol_7kD PF03604.8 EJS43378.1 - 9.7e-16 56.9 2.1 1.3e-15 56.5 1.4 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.1 EJS43378.1 - 0.0013 18.4 1.0 0.0018 17.9 0.7 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 DZR PF12773.2 EJS43378.1 - 0.0028 17.4 0.4 0.0038 17.0 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon TFIIS_C PF01096.13 EJS43378.1 - 0.0034 16.9 0.7 1.5 8.5 0.1 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) HypA PF01155.14 EJS43378.1 - 0.0043 16.7 0.2 0.0043 16.7 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 EJS43378.1 - 0.013 15.2 0.2 0.024 14.3 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 NCD3G PF07562.9 EJS43378.1 - 0.016 14.8 0.2 0.02 14.5 0.2 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR C1_1 PF00130.17 EJS43378.1 - 0.031 14.0 0.7 0.043 13.5 0.5 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2318 PF10080.4 EJS43378.1 - 0.032 13.9 0.1 0.037 13.8 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) FYVE_2 PF02318.11 EJS43378.1 - 0.039 13.8 0.4 0.043 13.7 0.3 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger DUF951 PF06107.6 EJS43378.1 - 0.046 13.2 1.3 1.3 8.5 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) DUF2197 PF09963.4 EJS43378.1 - 0.064 13.2 2.1 6 6.9 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zinc-ribbons_6 PF07191.7 EJS43378.1 - 0.066 13.0 0.3 0.089 12.5 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbons OrfB_Zn_ribbon PF07282.6 EJS43378.1 - 0.088 12.4 0.5 0.12 12.0 0.4 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Herpes_UL33 PF03581.8 EJS43378.1 - 0.091 12.6 0.2 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL33-like protein DUF4428 PF14471.1 EJS43378.1 - 0.094 12.4 2.0 1.2 8.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) Zn_ribbon_recom PF13408.1 EJS43378.1 - 0.13 12.5 3.0 2.1 8.7 0.4 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain A2L_zn_ribbon PF08792.5 EJS43378.1 - 0.16 11.4 1.2 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Ribosomal_L40e PF01020.12 EJS43378.1 - 0.23 11.0 3.1 0.3 10.7 2.1 1.2 1 0 0 1 1 1 0 Ribosomal L40e family TF_Zn_Ribbon PF08271.7 EJS43378.1 - 0.26 10.6 2.1 1.7 8.0 1.7 1.9 1 1 1 2 2 2 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 EJS43378.1 - 0.33 10.7 3.0 1.1 9.0 2.2 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 EJS43378.1 - 0.55 9.8 3.2 2.5 7.7 2.3 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EJS43378.1 - 0.7 9.6 3.6 3.4 7.4 2.5 2.0 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EJS43378.1 - 1.2 9.1 3.8 4.9 7.1 2.6 1.9 1 1 0 1 1 1 0 Zinc ribbon domain dCMP_cyt_deam_1 PF00383.17 EJS43379.1 - 4e-26 90.6 2.4 4e-26 90.6 1.7 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EJS43379.1 - 0.0073 15.9 2.3 0.19 11.3 0.5 2.2 2 0 0 2 2 2 2 APOBEC-like N-terminal domain DUF1839 PF08893.5 EJS43380.1 - 0.31 9.9 1.0 0.52 9.2 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) Ribosomal_L6 PF00347.18 EJS43381.1 - 4.3e-28 97.6 2.4 5.3e-15 55.6 0.3 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S4 PF00163.14 EJS43382.1 - 1.7e-26 92.4 1.5 7.5e-26 90.3 1.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EJS43382.1 - 8.5e-13 47.5 0.0 2e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.6 EJS43382.1 - 0.0012 17.3 0.1 0.0014 17.1 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus Latent membrane protein 2 SKG6 PF08693.5 EJS43383.1 - 4.1e-17 61.1 4.6 8.3e-17 60.2 3.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EJS43383.1 - 0.00012 21.6 0.4 0.0005 19.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.10 EJS43383.1 - 0.0004 19.8 1.9 0.00065 19.1 1.3 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM154 PF15102.1 EJS43383.1 - 0.00079 19.1 0.0 0.00079 19.1 0.0 2.6 3 0 0 3 3 3 1 TMEM154 protein family DUF912 PF06024.7 EJS43383.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 2.9 3 0 0 3 3 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rax2 PF12768.2 EJS43383.1 - 0.01 15.1 0.1 0.033 13.4 0.0 1.9 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Chordopox_A13L PF05961.6 EJS43383.1 - 0.097 12.6 0.3 1 9.3 0.0 2.8 2 0 0 2 2 2 0 Chordopoxvirus A13L protein PIRT PF15099.1 EJS43383.1 - 0.13 11.4 0.2 0.3 10.3 0.1 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family EphA2_TM PF14575.1 EJS43383.1 - 0.15 12.4 0.9 1.2 9.6 0.0 3.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain 7tm_1 PF00001.16 EJS43383.1 - 0.18 10.8 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Shisa PF13908.1 EJS43383.1 - 0.46 10.6 0.0 0.46 10.6 0.0 4.0 2 1 2 4 4 3 0 Wnt and FGF inhibitory regulator Lectin_C PF00059.16 EJS43384.1 - 0.014 16.0 4.7 6.3 7.5 1.9 3.1 3 1 0 3 3 3 0 Lectin C-type domain Spo12 PF05032.7 EJS43385.1 - 1.7e-17 62.6 0.8 1.7e-17 62.6 0.5 1.9 2 0 0 2 2 2 1 Spo12 family PH PF00169.24 EJS43387.1 - 1.8e-10 40.9 0.2 1.8e-10 40.9 0.2 3.1 2 1 0 2 2 2 1 PH domain Kelch_3 PF13415.1 EJS43389.1 - 4.1e-36 122.3 1.5 1.1e-07 31.7 0.0 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EJS43389.1 - 1.3e-33 114.4 6.4 8.1e-06 25.6 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EJS43389.1 - 1.7e-27 94.8 10.5 1.2e-05 25.0 0.1 6.8 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EJS43389.1 - 1.6e-25 88.1 4.4 8.9e-05 22.5 0.0 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EJS43389.1 - 7.6e-24 83.0 1.9 1.6e-06 27.5 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EJS43389.1 - 6e-14 51.1 8.6 0.0025 17.5 0.0 6.8 6 1 0 6 6 6 4 Kelch motif ANTH PF07651.11 EJS43390.1 - 3.9e-71 239.0 0.4 3.9e-71 239.0 0.3 1.6 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 EJS43390.1 - 1.3e-07 31.5 0.1 1.3e-07 31.5 0.1 1.9 2 0 0 2 2 2 1 ENTH domain AAA_23 PF13476.1 EJS43390.1 - 1.1 9.5 11.5 4 7.6 4.1 2.6 2 1 0 2 2 2 0 AAA domain MPC PF03650.8 EJS43391.1 - 6.6e-55 184.1 0.1 7.6e-55 184.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 EJS43391.1 - 0.022 14.6 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Dna2 PF08696.6 EJS43392.1 - 1.2e-65 220.7 0.3 9.9e-65 217.7 0.1 2.6 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 EJS43392.1 - 2.5e-48 164.1 0.1 2.5e-48 164.1 0.1 1.9 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 EJS43392.1 - 3.4e-34 118.4 19.6 8.8e-34 117.1 0.2 4.0 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.1 EJS43392.1 - 2.9e-14 53.1 0.0 8.2e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EJS43392.1 - 3e-08 33.2 0.0 6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain PIF1 PF05970.9 EJS43392.1 - 0.00033 19.7 0.0 0.00033 19.7 0.0 2.3 3 1 0 3 3 2 1 PIF1-like helicase Cas_Cas4 PF01930.12 EJS43392.1 - 0.00034 20.5 0.0 0.002 18.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 Helicase_RecD PF05127.9 EJS43392.1 - 0.00077 19.1 0.3 0.0021 17.6 0.0 2.0 2 0 0 2 2 1 1 Helicase Viral_helicase1 PF01443.13 EJS43392.1 - 0.00094 18.7 3.6 0.36 10.3 0.1 4.3 3 1 1 4 4 4 1 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 EJS43392.1 - 0.0014 18.1 0.0 0.0038 16.7 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EJS43392.1 - 0.0016 18.5 0.2 0.0056 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 EJS43392.1 - 0.0018 17.9 1.7 0.0034 17.1 0.1 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 EJS43392.1 - 0.007 15.6 0.1 0.044 13.0 0.0 2.2 1 1 0 1 1 1 1 PhoH-like protein CbiA PF01656.18 EJS43392.1 - 0.035 13.5 3.2 0.044 13.1 0.1 2.8 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EJS43392.1 - 0.054 13.6 0.1 0.51 10.4 0.0 2.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EJS43392.1 - 0.081 13.2 0.0 0.081 13.2 0.0 3.9 4 1 0 4 4 2 0 AAA domain AAA_25 PF13481.1 EJS43392.1 - 0.082 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 EJS43392.1 - 0.098 12.7 0.0 0.53 10.4 0.0 2.4 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain ArgK PF03308.11 EJS43392.1 - 0.14 10.9 1.8 0.17 10.6 0.0 2.0 3 0 0 3 3 3 0 ArgK protein AAA_29 PF13555.1 EJS43392.1 - 0.15 11.5 0.1 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain APC8 PF04049.8 EJS43393.1 - 6.3e-37 126.4 0.3 1.6e-36 125.1 0.2 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EJS43393.1 - 2.7e-27 93.1 12.5 0.00011 21.6 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 EJS43393.1 - 1.4e-23 82.3 16.1 2.1e-08 33.6 0.1 5.9 6 1 1 7 7 7 4 TPR repeat TPR_2 PF07719.12 EJS43393.1 - 7.2e-22 75.4 10.7 0.02 14.7 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 EJS43393.1 - 2.7e-21 73.7 23.3 0.0007 19.1 0.0 9.0 9 1 1 10 10 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 EJS43393.1 - 6.3e-18 64.4 10.7 0.00026 20.8 0.2 5.7 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EJS43393.1 - 3.5e-13 48.9 0.0 0.01 16.3 0.0 7.8 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EJS43393.1 - 1.9e-11 43.1 6.6 0.002 18.1 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EJS43393.1 - 4.6e-11 41.6 2.1 0.09 12.6 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EJS43393.1 - 2.8e-09 37.4 1.4 0.017 15.8 0.0 6.5 7 1 1 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EJS43393.1 - 7.9e-08 32.3 15.5 0.00095 19.2 1.2 6.0 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.5 EJS43393.1 - 6.7e-06 25.1 0.0 4.2e-05 22.4 0.0 2.1 1 1 2 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 EJS43393.1 - 1e-05 25.7 7.6 0.84 10.0 0.0 6.5 7 1 1 8 8 6 2 Tetratricopeptide repeat RPN7 PF10602.4 EJS43393.1 - 1.2e-05 24.8 4.3 9.3e-05 21.8 0.1 3.4 3 0 0 3 3 3 1 26S proteasome subunit RPN7 MIT PF04212.13 EJS43393.1 - 5.2e-05 23.0 0.1 0.063 13.1 0.0 3.4 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 EJS43393.1 - 0.00062 18.9 1.0 0.39 9.7 0.1 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EJS43393.1 - 0.0007 19.8 14.9 3.9 8.1 0.0 8.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_10 PF13374.1 EJS43393.1 - 0.0052 16.6 0.0 1.2 9.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EJS43393.1 - 0.017 14.9 0.1 0.77 9.6 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat UBN2_3 PF14244.1 EJS43393.1 - 0.031 13.8 0.3 0.089 12.3 0.2 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type THP2 PF09432.5 EJS43394.1 - 1.4e-56 189.9 2.7 1.4e-56 189.9 1.9 1.5 2 0 0 2 2 2 1 Tho complex subunit THP2 Phasin PF05597.6 EJS43394.1 - 0.13 12.0 2.0 8.3 6.1 0.0 3.3 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF342 PF03961.8 EJS43394.1 - 1.1 7.6 5.9 5.5 5.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DivIVA PF05103.8 EJS43394.1 - 1.4 9.0 5.4 0.49 10.4 0.1 2.7 2 2 1 3 3 3 0 DivIVA protein COX16 PF14138.1 EJS43394.1 - 2.6 8.2 4.8 0.7 10.1 0.5 2.1 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 NMD3 PF04981.8 EJS43395.1 - 5.9e-75 251.4 1.2 5.9e-75 251.4 0.8 1.6 2 0 0 2 2 2 1 NMD3 family FYVE PF01363.16 EJS43395.1 - 0.44 10.4 5.2 0.59 10.0 1.5 2.3 2 0 0 2 2 2 0 FYVE zinc finger zinc_ribbon_6 PF14599.1 EJS43395.1 - 0.66 9.8 0.1 0.66 9.8 0.0 3.0 2 1 1 3 3 3 0 Zinc-ribbon DZR PF12773.2 EJS43395.1 - 0.7 9.7 8.0 3.5 7.5 3.6 2.8 2 1 1 3 3 3 0 Double zinc ribbon ThiF PF00899.16 EJS43396.1 - 7.6e-30 103.4 0.0 1.9e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EJS43396.1 - 0.00034 20.7 0.0 0.0014 18.7 0.0 2.0 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Spc97_Spc98 PF04130.8 EJS43397.1 - 4.1e-72 243.2 20.9 5.5e-72 242.8 14.5 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Mannitol_dh_C PF08125.8 EJS43397.1 - 0.012 14.7 0.5 0.05 12.7 0.1 2.1 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain Enolase_C PF00113.17 EJS43398.1 - 3.7e-151 502.1 0.0 5.9e-151 501.4 0.0 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EJS43398.1 - 6.9e-55 184.5 1.1 1.2e-54 183.7 0.8 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EJS43398.1 - 0.0017 18.2 0.1 0.0073 16.2 0.0 2.1 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EJS43398.1 - 0.015 14.2 0.3 0.053 12.4 0.0 1.9 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EJS43398.1 - 0.035 14.6 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain FMO-like PF00743.14 EJS43399.1 - 8.9e-41 139.6 1.3 2.9e-33 114.9 0.1 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EJS43399.1 - 1.3e-15 58.0 0.0 1.1e-14 55.0 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EJS43399.1 - 1.3e-12 47.7 0.3 2.6e-10 40.2 0.0 3.5 3 2 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EJS43399.1 - 7.3e-09 35.7 0.0 4.2e-07 30.0 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EJS43399.1 - 8.4e-08 31.4 2.5 2.7e-06 26.5 0.1 2.9 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EJS43399.1 - 2.3e-05 23.6 0.1 0.0099 14.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 EJS43399.1 - 0.00024 21.0 0.0 0.00062 19.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EJS43399.1 - 0.0013 17.3 0.3 0.89 7.9 0.0 2.5 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 EJS43399.1 - 0.042 12.7 0.0 4.3 6.1 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EJS43399.1 - 0.084 12.5 0.3 17 5.0 0.1 2.6 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 EJS43399.1 - 0.22 11.9 0.9 15 6.0 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 EJS43399.1 - 0.26 10.6 2.6 10 5.4 0.3 3.0 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Fungal_trans PF04082.13 EJS43400.1 - 1.6e-34 118.9 0.0 2.7e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS43400.1 - 3e-07 30.2 12.3 5.4e-07 29.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1216 PF06746.6 EJS43400.1 - 0.14 11.9 2.0 0.22 11.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) Dickkopf_N PF04706.7 EJS43400.1 - 4.2 7.5 10.8 1.3 9.2 4.8 2.2 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Oxidored_FMN PF00724.15 EJS43401.1 - 7.1e-134 446.1 0.0 8.1e-134 445.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ribosomal_L30_N PF08079.7 EJS43401.1 - 0.11 12.4 2.1 0.26 11.3 1.4 1.6 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Erv26 PF04148.8 EJS43402.1 - 8.9e-88 293.1 5.7 1e-87 292.9 3.9 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.15 EJS43402.1 - 0.5 9.8 5.6 0.18 11.3 1.4 2.1 1 1 1 2 2 2 0 Cytochrome C assembly protein RhoGAP PF00620.22 EJS43403.1 - 3.1e-05 23.6 0.7 0.00027 20.5 0.1 2.7 2 0 0 2 2 2 1 RhoGAP domain EF1G PF00647.14 EJS43403.1 - 0.076 12.7 4.6 11 5.7 0.0 3.6 3 0 0 3 3 3 0 Elongation factor 1 gamma, conserved domain 6PGD PF00393.14 EJS43404.1 - 2.7e-130 433.7 0.0 3.4e-130 433.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EJS43404.1 - 1.1e-52 178.1 0.0 1.6e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EJS43404.1 - 0.018 15.4 0.1 0.037 14.4 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EJS43404.1 - 0.029 14.4 0.0 0.093 12.7 0.0 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EJS43404.1 - 0.15 11.2 0.0 0.39 9.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PC_rep PF01851.17 EJS43406.1 - 1.7e-25 87.7 11.9 5.8e-07 29.4 0.1 8.4 9 0 0 9 9 9 6 Proteasome/cyclosome repeat DPPIV_N PF00930.16 EJS43407.1 - 6.4e-107 357.1 7.4 8.7e-107 356.7 5.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EJS43407.1 - 3.2e-52 176.8 1.3 5.6e-52 176.0 0.9 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EJS43407.1 - 6.5e-09 35.6 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EJS43407.1 - 5.8e-05 23.0 0.1 0.00047 20.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EJS43407.1 - 0.028 13.8 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PhzC-PhzF PF02567.11 EJS43408.1 - 2.7e-77 259.7 0.1 3.1e-77 259.5 0.1 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DAP_epimerase PF01678.14 EJS43408.1 - 0.019 14.8 0.0 0.058 13.3 0.0 1.8 2 0 0 2 2 2 0 Diaminopimelate epimerase ArsD PF06953.6 EJS43408.1 - 0.11 12.6 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Arsenical resistance operon trans-acting repressor ArsD Pkinase PF00069.20 EJS43409.1 - 1.7e-67 227.2 0.2 2.7e-67 226.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43409.1 - 4.5e-31 107.8 0.0 9.4e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EJS43409.1 - 0.064 12.9 1.1 0.1 12.3 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1635 PF07795.6 EJS43409.1 - 0.078 12.3 5.9 0.14 11.5 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) APC_CDC26 PF10471.4 EJS43409.1 - 0.74 10.5 10.3 1.5 9.5 7.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 PIF1 PF05970.9 EJS43410.1 - 1e-52 179.3 4.4 4.8e-46 157.3 1.3 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EJS43410.1 - 1e-17 64.3 0.0 2.4e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EJS43410.1 - 2.1e-07 31.1 0.3 2.8e-06 27.4 0.1 2.7 3 0 0 3 3 3 1 AAA domain Herpes_Helicase PF02689.9 EJS43410.1 - 1.8e-05 22.7 0.1 0.0021 15.9 0.0 2.2 2 0 0 2 2 2 2 Helicase AAA PF00004.24 EJS43410.1 - 0.00024 21.3 0.2 0.00077 19.6 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EJS43410.1 - 0.00034 20.2 0.2 0.001 18.7 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 EJS43410.1 - 0.00056 18.8 0.3 0.001 18.0 0.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EJS43410.1 - 0.0029 17.1 0.9 0.36 10.3 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EJS43410.1 - 0.0038 16.8 0.2 0.014 15.0 0.2 2.0 1 1 0 1 1 1 1 Helicase PhoH PF02562.11 EJS43410.1 - 0.0052 16.0 0.1 0.015 14.5 0.1 1.7 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 EJS43410.1 - 0.012 14.6 0.1 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EJS43410.1 - 0.012 15.0 0.1 0.047 13.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EJS43410.1 - 0.014 14.5 0.2 0.035 13.2 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.1 EJS43410.1 - 0.016 15.3 0.1 0.43 10.7 0.0 2.7 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 EJS43410.1 - 0.034 13.8 0.3 0.14 11.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EJS43410.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EJS43410.1 - 0.074 13.3 0.9 0.25 11.6 0.3 2.0 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 EJS43410.1 - 0.17 12.0 1.2 0.91 9.7 0.2 2.5 2 1 0 2 2 2 0 RNA helicase AAA_11 PF13086.1 EJS43410.1 - 0.42 10.1 6.2 1.3 8.5 0.2 2.9 2 1 1 3 3 2 0 AAA domain AA_kinase PF00696.23 EJS43411.1 - 1.6e-37 129.3 0.1 2.6e-37 128.6 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EJS43411.1 - 5.1e-19 67.7 0.0 1e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 PUA domain PIH1 PF08190.7 EJS43412.1 - 3.8e-22 79.1 0.4 8.3e-22 78.0 0.2 1.5 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Brr6_like_C_C PF10104.4 EJS43413.1 - 3.3e-45 152.9 4.2 4.9e-45 152.3 2.9 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Aldedh PF00171.17 EJS43414.1 - 5.1e-99 331.6 0.0 6.2e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.14 EJS43415.1 - 3.9e-36 123.9 3.0 3.9e-36 123.9 2.1 1.4 2 0 0 2 2 2 1 Ribosome recycling factor Cor1 PF04803.7 EJS43415.1 - 0.00021 21.0 0.9 0.00021 21.0 0.6 2.5 2 1 0 2 2 2 1 Cor1/Xlr/Xmr conserved region DUF2884 PF11101.3 EJS43415.1 - 0.0091 15.3 1.5 0.041 13.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2884) DUF2115 PF09888.4 EJS43415.1 - 0.0099 15.9 6.7 0.083 12.9 1.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2115) DUF2580 PF10824.3 EJS43415.1 - 0.11 12.7 0.1 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) DUF4230 PF14014.1 EJS43415.1 - 0.18 11.6 3.8 5.9 6.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) Pox_polyA_pol_N PF12630.2 EJS43415.1 - 0.68 10.0 6.8 0.11 12.5 1.4 2.2 2 2 1 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain FliD_C PF07195.7 EJS43415.1 - 1 8.6 8.5 0.22 10.7 1.0 2.3 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Aldedh PF00171.17 EJS43416.1 - 2e-125 418.7 0.0 2.4e-125 418.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_1 PF00667.15 EJS43417.1 - 1.6e-71 240.2 0.0 2.5e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EJS43417.1 - 2.4e-30 105.3 1.0 4.2e-30 104.6 0.7 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EJS43417.1 - 8.9e-22 77.7 0.0 2.3e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EJS43417.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Spore_IV_A PF09547.5 EJS43417.1 - 0.035 12.7 0.2 0.061 12.0 0.1 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) HAD_2 PF13419.1 EJS43418.1 - 1.6e-13 51.2 0.0 3e-13 50.3 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EJS43418.1 - 7.6e-07 28.7 0.1 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EJS43418.1 - 2.5e-05 24.8 0.1 0.0002 21.8 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EJS43418.1 - 0.018 15.2 0.0 0.026 14.6 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Inositol_P PF00459.20 EJS43420.1 - 2.6e-70 236.7 0.0 2.9e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1953 PF09196.5 EJS43420.1 - 0.057 13.1 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) T4_Gp59_C PF08994.5 EJS43420.1 - 0.085 13.0 0.0 8.9 6.5 0.0 2.3 2 0 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase C-term FSH1 PF03959.8 EJS43421.1 - 3.4e-63 212.9 0.0 3.8e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EJS43421.1 - 0.00017 21.3 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EJS43421.1 - 0.0012 18.2 0.0 0.88 8.9 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase BAAT_C PF08840.6 EJS43421.1 - 0.0024 17.5 0.0 0.43 10.2 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal COX5A PF02284.11 EJS43422.1 - 1.5e-51 172.9 0.9 1.9e-51 172.5 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Nterm_IS4 PF13006.2 EJS43422.1 - 0.072 13.1 0.1 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal Ribosomal_L1 PF00687.16 EJS43423.1 - 1.3e-41 142.3 10.9 2.6e-41 141.3 7.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Peptidase_S48 PF03574.10 EJS43423.1 - 0.13 12.2 0.9 0.71 9.8 0.3 2.2 2 0 0 2 2 2 0 Peptidase family S48 Zn_clus PF00172.13 EJS43424.1 - 5.3e-08 32.6 8.8 9.3e-08 31.8 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 EJS43425.1 - 6.5e-44 149.8 0.8 7.6e-44 149.6 0.6 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med6 PF04934.9 EJS43426.1 - 7.7e-54 181.0 0.7 1e-53 180.6 0.5 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.5 EJS43427.1 - 1.3e-27 95.4 0.4 1.8e-27 94.9 0.3 1.3 1 0 0 1 1 1 1 IGR protein motif PBD PF00786.23 EJS43428.1 - 0.0043 17.4 0.8 0.0043 17.4 0.5 2.8 2 1 0 2 2 2 1 P21-Rho-binding domain RNase_P_p30 PF01876.11 EJS43429.1 - 9.8e-48 161.1 0.1 1.5e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 ApbA PF02558.11 EJS43430.1 - 4.1e-33 113.9 0.0 6.3e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EJS43430.1 - 7.7e-24 84.0 0.0 1.3e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 EJS43430.1 - 0.0015 18.2 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HSP70 PF00012.15 EJS43431.1 - 6e-78 262.2 3.4 5.1e-77 259.1 0.7 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EJS43431.1 - 2e-11 43.0 0.0 3e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Actin PF00022.14 EJS43431.1 - 0.0092 14.4 0.1 0.035 12.5 0.0 1.9 1 1 0 2 2 2 1 Actin PilM_2 PF11104.3 EJS43431.1 - 0.016 14.1 0.1 0.028 13.2 0.1 1.4 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; PEP-utilizers PF00391.18 EJS43431.1 - 0.066 12.7 0.0 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain DEAD PF00270.24 EJS43432.1 - 1.2e-47 161.5 0.0 2.4e-47 160.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS43432.1 - 9.2e-26 89.5 0.0 2.5e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EJS43432.1 - 1.7e-06 27.9 0.8 1.7e-05 24.7 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EJS43432.1 - 0.0083 15.8 0.3 0.11 12.2 0.0 2.8 4 0 0 4 4 4 1 Part of AAA domain Brix PF04427.13 EJS43433.1 - 2.9e-61 206.4 3.9 4.1e-61 205.9 2.7 1.2 1 0 0 1 1 1 1 Brix domain DUF2514 PF10721.4 EJS43433.1 - 0.019 14.6 6.8 0.039 13.6 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) MaoC_dehydratas PF01575.14 EJS43434.1 - 0.0043 16.4 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain DS PF01916.12 EJS43435.1 - 1.6e-149 496.9 0.0 1.9e-149 496.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Met_10 PF02475.11 EJS43436.1 - 4.4e-80 267.9 0.0 7.5e-80 267.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.10 EJS43436.1 - 0.0019 17.6 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.11 EJS43436.1 - 0.0057 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.2 EJS43436.1 - 0.055 14.0 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EJS43436.1 - 0.072 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EJS43436.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cyclin PF08613.6 EJS43437.1 - 3.9e-09 37.0 0.2 4.8e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EJS43437.1 - 8.1e-09 35.1 0.5 1.4e-08 34.4 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Nop10p PF04135.7 EJS43438.1 - 9.2e-22 76.5 0.1 1.1e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family CN_hydrolase PF00795.17 EJS43439.1 - 4.2e-26 91.4 0.0 6.4e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EJS43439.1 - 7.7e-22 77.3 0.0 2.2e-21 75.8 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EJS43439.1 - 0.01 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase SpoIIE PF07228.7 EJS43440.1 - 4.5e-39 134.1 0.0 7.2e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EJS43440.1 - 3.6e-08 33.1 0.1 0.00026 20.4 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EJS43440.1 - 6.5e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C NLBH PF05211.7 EJS43440.1 - 0.025 13.8 0.1 0.047 12.9 0.1 1.4 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Strep_67kDa_ant PF06100.6 EJS43440.1 - 0.05 11.9 0.0 0.069 11.4 0.0 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family ABA_GPCR PF12430.3 EJS43441.1 - 7.3e-66 221.0 4.4 7.3e-66 221.0 3.0 2.4 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EJS43441.1 - 1.1e-17 63.7 1.1 2.7e-17 62.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) V-SNARE PF05008.10 EJS43441.1 - 1.4 9.1 3.8 0.85 9.8 1.1 1.8 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Pkinase PF00069.20 EJS43442.1 - 1.2e-44 152.4 0.0 2.2e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EJS43442.1 - 2.9e-42 143.5 0.3 7.7e-42 142.1 0.2 1.8 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EJS43442.1 - 9.1e-23 80.6 0.0 4.7e-22 78.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EJS43442.1 - 0.00028 20.0 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ PF01011.16 EJS43442.1 - 0.0018 17.7 0.2 0.21 11.1 0.0 3.6 4 0 0 4 4 4 1 PQQ enzyme repeat PQQ_2 PF13360.1 EJS43442.1 - 0.032 13.6 0.0 0.083 12.3 0.0 1.6 1 0 0 1 1 1 0 PQQ-like domain APH PF01636.18 EJS43442.1 - 0.16 11.7 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sas10_Utp3 PF04000.10 EJS43443.1 - 1.2e-08 34.9 3.9 1.2e-08 34.9 2.7 2.0 2 1 0 2 2 2 1 Sas10/Utp3/C1D family DUF1664 PF07889.7 EJS43443.1 - 0.033 14.0 4.4 0.078 12.7 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Methyltransf_10 PF05971.7 EJS43443.1 - 0.05 12.7 0.2 0.064 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF890) DUF1843 PF08898.5 EJS43443.1 - 0.14 12.2 1.0 23 5.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF885 PF05960.6 EJS43443.1 - 0.15 11.1 2.7 0.17 11.0 1.9 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF904 PF06005.7 EJS43443.1 - 3.6 7.9 10.1 0.68 10.2 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Pkinase PF00069.20 EJS43444.1 - 4.7e-46 157.0 4.9 1.3e-42 145.7 0.8 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43444.1 - 6.3e-20 71.3 2.9 1.3e-19 70.2 0.1 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43444.1 - 0.00052 19.0 0.0 0.00093 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RseA_C PF03873.8 EJS43444.1 - 0.072 12.9 0.2 0.072 12.9 0.2 2.9 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain DUF2731 PF10806.3 EJS43445.1 - 1.1e-39 135.4 0.0 2.5e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2731) STE PF02200.11 EJS43446.1 - 4.5e-60 200.6 3.2 7.1e-60 199.9 2.2 1.3 1 0 0 1 1 1 1 STE like transcription factor Ipi1_N PF12333.3 EJS43447.1 - 3.4e-26 91.1 0.1 8.9e-26 89.8 0.1 1.8 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation Sec7_N PF12783.2 EJS43447.1 - 0.055 12.9 1.7 0.09 12.1 1.2 1.3 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT_2 PF13646.1 EJS43447.1 - 0.07 13.4 0.0 0.48 10.7 0.0 2.4 1 1 1 2 2 2 0 HEAT repeats Lant_dehyd_N PF04737.8 EJS43447.1 - 0.12 12.3 0.1 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Lantibiotic dehydratase, N terminus RRM_1 PF00076.17 EJS43448.1 - 9.7e-43 143.6 0.0 1.2e-16 60.1 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS43448.1 - 4.2e-24 84.3 0.0 1.5e-07 31.2 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS43448.1 - 3.4e-15 55.6 0.0 1.2e-07 31.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EJS43448.1 - 0.018 14.8 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.1 EJS43448.1 - 0.041 13.6 0.0 0.086 12.6 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Brix PF04427.13 EJS43449.1 - 2e-39 135.2 2.8 3e-39 134.6 1.9 1.3 1 0 0 1 1 1 1 Brix domain Gar1 PF04410.9 EJS43450.1 - 7e-44 148.9 0.1 1.1e-43 148.4 0.0 1.3 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region ING PF12998.2 EJS43451.1 - 1.2e-22 80.1 5.5 1.2e-22 80.1 3.8 1.8 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EJS43451.1 - 1.6e-10 40.5 8.4 3.4e-10 39.4 5.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EJS43451.1 - 0.26 11.4 4.6 0.17 12.0 1.5 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain RAMP4 PF06624.7 EJS43451.1 - 0.64 9.6 2.4 3.1 7.4 0.1 2.4 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 tRNA-synt_1d PF00750.14 EJS43452.1 - 1.1e-119 399.4 5.1 1.3e-119 399.1 3.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EJS43452.1 - 1.1e-24 86.7 0.1 1.4e-23 83.0 0.0 2.6 2 1 1 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EJS43452.1 - 2.5e-05 24.7 0.0 6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Sugar_tr PF00083.19 EJS43453.1 - 5.6e-175 582.2 37.7 6.4e-175 582.0 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS43453.1 - 1.4e-31 109.5 33.1 1.1e-28 100.0 14.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec23_trunk PF04811.10 EJS43454.1 - 1.4e-65 221.0 0.1 3e-65 219.9 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EJS43454.1 - 6.1e-21 73.7 0.9 1.7e-20 72.3 0.2 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EJS43454.1 - 1.6e-14 54.1 0.0 3.9e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EJS43454.1 - 7.4e-13 47.8 2.9 1.5e-12 46.8 2.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EJS43454.1 - 5.8e-09 35.5 0.0 2.9e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat FAT PF02259.18 EJS43455.1 - 1.8e-70 237.6 8.6 3.5e-70 236.7 5.9 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EJS43455.1 - 2.7e-54 184.1 5.2 4.3e-54 183.4 0.8 3.2 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EJS43455.1 - 3.1e-07 29.6 0.0 8.5e-07 28.2 0.0 1.8 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 EJS43455.1 - 0.011 15.4 2.8 0.035 13.7 0.2 2.9 3 0 0 3 3 3 0 TPR repeat Ponericin PF07442.6 EJS43455.1 - 0.93 9.3 0.3 2 8.2 0.2 1.5 1 0 0 1 1 1 0 Ponericin PGP_phosphatase PF09419.5 EJS43456.1 - 1.5e-71 239.1 0.0 1.7e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EJS43456.1 - 6.7e-05 22.5 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like GSH_synthase PF03199.10 EJS43456.1 - 0.054 13.5 0.0 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase Pkinase PF00069.20 EJS43457.1 - 1.5e-69 234.0 0.0 2.3e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43457.1 - 1.4e-49 168.4 0.0 2.3e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43457.1 - 6.4e-06 25.3 0.1 2.8e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EJS43457.1 - 0.31 10.7 0.0 0.57 9.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Aldo_ket_red PF00248.16 EJS43459.1 - 2.1e-49 167.8 0.0 2.5e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pyr_redox_2 PF07992.9 EJS43460.1 - 1.6e-27 96.6 0.0 2.2e-27 96.2 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EJS43460.1 - 2.9e-18 66.0 0.2 4.9e-15 55.6 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EJS43460.1 - 1.8e-09 37.9 0.0 2.3e-06 27.8 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EJS43460.1 - 5.2e-05 22.2 1.1 0.52 9.1 0.1 4.1 3 1 1 4 4 4 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EJS43460.1 - 7.8e-05 22.8 0.0 0.043 14.0 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.12 EJS43460.1 - 0.00025 20.2 0.1 0.0035 16.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EJS43460.1 - 0.0003 20.7 0.0 0.028 14.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EJS43460.1 - 0.00094 18.1 0.1 2.2 7.0 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EJS43460.1 - 0.0038 17.3 0.2 3.8 7.5 0.1 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EJS43460.1 - 0.0057 15.1 0.4 0.97 7.8 0.1 2.8 2 1 1 3 3 3 1 HI0933-like protein K_oxygenase PF13434.1 EJS43460.1 - 0.0095 14.8 0.0 0.73 8.6 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EJS43460.1 - 0.079 12.7 0.0 5.4 6.7 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EJS43460.1 - 0.085 11.8 0.0 8.8 5.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 EJS43460.1 - 0.15 10.9 2.4 1.3 7.8 0.1 2.6 2 2 0 2 2 2 0 FAD binding domain Septin PF00735.13 EJS43461.1 - 9.8e-120 398.8 0.1 1.5e-119 398.2 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EJS43461.1 - 5.3e-07 29.6 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EJS43461.1 - 1.2e-05 24.6 0.0 3.4e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EJS43461.1 - 0.00032 20.3 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EJS43461.1 - 0.00061 19.9 0.2 0.01 15.9 0.1 2.6 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EJS43461.1 - 0.0011 18.4 0.9 0.029 13.7 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EJS43461.1 - 0.0043 17.0 0.0 0.073 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.11 EJS43461.1 - 0.0048 16.0 0.1 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 EJS43461.1 - 0.0051 17.3 0.1 0.044 14.2 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EJS43461.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 EJS43461.1 - 0.0097 16.0 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 EJS43461.1 - 0.013 15.1 0.0 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 EJS43461.1 - 0.014 15.6 0.1 0.047 13.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter IIGP PF05049.8 EJS43461.1 - 0.022 13.5 0.0 0.054 12.3 0.0 1.7 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.1 EJS43461.1 - 0.024 14.5 0.1 0.069 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain Dynamin_N PF00350.18 EJS43461.1 - 0.031 14.1 4.6 8.6 6.1 0.0 3.3 2 1 1 3 3 3 0 Dynamin family Sigma54_activat PF00158.21 EJS43461.1 - 0.047 13.1 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.7 EJS43461.1 - 0.048 12.9 0.1 0.087 12.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_10 PF12846.2 EJS43461.1 - 0.054 12.9 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain Gtr1_RagA PF04670.7 EJS43461.1 - 0.057 12.5 0.1 0.23 10.5 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EJS43461.1 - 0.14 11.6 1.4 0.62 9.5 0.2 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3970 PF13113.1 EJS43461.1 - 2.7 7.7 5.3 27 4.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) VHS PF00790.14 EJS43462.1 - 1.2e-49 167.5 0.1 5.2e-49 165.5 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 EJS43462.1 - 7.1e-26 90.7 1.4 1.7e-25 89.6 1.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 EJS43462.1 - 3.2e-14 52.7 3.5 8.4e-14 51.3 2.4 1.7 1 0 0 1 1 1 1 GAT domain PrkA PF06798.7 EJS43462.1 - 0.023 14.0 0.1 0.87 8.8 0.0 2.2 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain GP41 PF00517.12 EJS43462.1 - 0.043 13.3 1.7 0.1 12.1 1.2 1.6 1 0 0 1 1 1 0 Retroviral envelope protein EMP24_GP25L PF01105.19 EJS43464.1 - 2.5e-49 167.4 1.4 2.8e-49 167.3 1.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NTR2 PF15458.1 EJS43464.1 - 0.033 13.4 1.4 0.049 12.8 1.0 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 ThiF PF00899.16 EJS43465.1 - 1.5e-42 144.6 0.0 2.5e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EJS43465.1 - 6.1e-27 93.0 0.4 1e-26 92.3 0.3 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EJS43465.1 - 4.2e-13 49.6 0.0 8.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EJS43465.1 - 0.00014 21.9 0.0 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Herpes_BLRF2 PF05812.7 EJS43465.1 - 0.089 12.6 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein NAD_binding_7 PF13241.1 EJS43465.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Shugoshin_N PF07558.6 EJS43465.1 - 0.19 11.4 0.9 0.4 10.4 0.6 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Cys_Met_Meta_PP PF01053.15 EJS43466.1 - 4.5e-65 219.4 0.1 1.3e-64 217.8 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EJS43466.1 - 0.00032 19.5 0.0 0.00052 18.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EJS43466.1 - 0.0039 16.1 0.0 0.0074 15.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.8 EJS43466.1 - 0.032 12.9 0.0 0.047 12.4 0.0 1.1 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Peptidase_M18 PF02127.10 EJS43467.1 - 1.2e-180 600.6 0.0 1.3e-180 600.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EJS43467.1 - 1.8e-07 30.2 0.0 0.0001 21.2 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase CBM_2 PF00553.14 EJS43467.1 - 0.093 12.7 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Cellulose binding domain SH3_9 PF14604.1 EJS43468.1 - 1.5e-26 91.7 0.4 6e-15 54.5 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EJS43468.1 - 1.8e-25 88.0 0.6 9e-12 44.2 0.1 2.7 2 0 0 2 2 2 2 SH3 domain FCH PF00611.18 EJS43468.1 - 1.1e-23 83.2 2.4 1.7e-23 82.6 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 EJS43468.1 - 5.1e-14 51.5 0.1 4.5e-08 32.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain FHA PF00498.21 EJS43469.1 - 4.6e-16 58.6 0.4 8.4e-16 57.8 0.3 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EJS43469.1 - 1.5e-05 24.6 10.5 2.7e-05 23.9 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EJS43469.1 - 2.5e-05 24.2 4.4 4.8e-05 23.3 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger Mucin PF01456.12 EJS43469.1 - 0.0025 17.6 7.7 0.0045 16.7 5.3 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein zf-Apc11 PF12861.2 EJS43469.1 - 0.0051 16.6 4.8 0.01 15.6 3.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EJS43469.1 - 0.0061 16.1 11.1 0.011 15.3 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EJS43469.1 - 0.018 14.7 8.7 0.03 14.0 6.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Sec_GG PF07549.9 EJS43469.1 - 0.033 13.4 0.3 0.077 12.2 0.2 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-HC5HC2H PF13771.1 EJS43469.1 - 0.054 13.6 4.2 0.11 12.6 2.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain SSP160 PF06933.6 EJS43469.1 - 0.064 11.2 11.4 0.1 10.5 7.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-C3HC4_2 PF13923.1 EJS43469.1 - 0.076 13.0 12.2 0.14 12.1 8.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3439 PF11921.3 EJS43469.1 - 0.23 11.2 7.1 0.62 9.8 4.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-RING-like PF08746.6 EJS43469.1 - 0.6 10.1 7.5 1.3 9.1 5.2 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EJS43469.1 - 1.3 8.7 6.9 2.5 7.8 4.8 1.5 1 0 0 1 1 1 0 PHD-finger TPR_11 PF13414.1 EJS43470.1 - 1.4e-45 152.8 14.0 8e-19 67.0 0.0 6.9 4 3 2 6 6 6 5 TPR repeat TPR_1 PF00515.23 EJS43470.1 - 6.7e-36 120.4 17.2 1.8e-07 30.4 0.4 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EJS43470.1 - 5.5e-34 113.3 15.3 6.5e-06 25.6 0.1 10.8 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 EJS43470.1 - 3.1e-23 81.8 0.2 0.00027 21.5 0.0 6.4 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EJS43470.1 - 2.6e-21 75.6 20.5 2.4e-06 27.7 0.0 7.0 5 2 2 8 8 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EJS43470.1 - 5.2e-21 73.0 9.4 0.00067 19.6 0.0 7.7 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EJS43470.1 - 1.5e-19 68.2 12.4 0.00033 20.2 0.0 9.6 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EJS43470.1 - 1.4e-18 65.6 1.4 0.058 14.0 0.0 10.1 4 3 7 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.1 EJS43470.1 - 1.1e-17 63.7 14.1 2.9e-05 23.8 0.0 7.7 4 2 5 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 EJS43470.1 - 9.5e-12 44.6 0.1 0.031 14.1 0.0 5.0 5 1 0 5 5 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EJS43470.1 - 4.9e-11 42.6 7.8 0.019 15.0 0.1 5.0 3 1 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EJS43470.1 - 7.4e-11 41.0 4.5 0.08 12.7 0.0 8.2 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EJS43470.1 - 0.0021 18.4 19.2 5.1 7.7 0.1 7.7 9 0 0 9 9 6 1 Tetratricopeptide repeat Sel1 PF08238.7 EJS43470.1 - 0.011 16.3 0.0 24 5.7 0.0 4.8 4 0 0 4 4 4 0 Sel1 repeat TPR_5 PF12688.2 EJS43470.1 - 0.016 15.2 0.1 4 7.4 0.0 3.9 4 0 0 4 4 4 0 Tetratrico peptide repeat TPR_10 PF13374.1 EJS43470.1 - 0.038 13.9 0.0 11 6.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EJS43470.1 - 0.091 12.6 5.3 11 5.9 0.1 4.8 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 EJS43470.1 - 0.17 11.7 23.1 0.082 12.7 0.3 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF2681 PF10883.3 EJS43470.1 - 5.9 7.1 9.5 0.21 11.8 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) ORC6 PF05460.8 EJS43471.1 - 2.5e-100 336.0 4.6 3e-100 335.7 3.2 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Integrase_Zn PF02022.14 EJS43471.1 - 0.073 12.5 0.6 0.3 10.5 0.0 2.3 2 0 0 2 2 2 0 Integrase Zinc binding domain CDC45 PF02724.9 EJS43471.1 - 1.6 6.6 11.3 2.5 6.0 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein N-SET PF11764.3 EJS43472.1 - 3.2e-42 144.2 2.3 3.2e-42 144.2 1.6 4.3 6 0 0 6 6 6 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 EJS43472.1 - 7.6e-23 81.5 0.2 7.6e-23 81.5 0.2 4.0 4 2 0 4 4 4 1 SET domain SET_assoc PF11767.3 EJS43472.1 - 1.4e-21 75.5 0.4 1.4e-21 75.5 0.2 2.4 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated MutS_V PF00488.16 EJS43473.1 - 1.4e-77 260.2 0.0 2.2e-77 259.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EJS43473.1 - 8.2e-35 120.4 6.1 9.6e-35 120.2 3.3 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EJS43473.1 - 2.6e-29 101.5 0.1 5.9e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EJS43473.1 - 2.2e-10 40.7 0.4 1.3e-09 38.2 0.0 2.4 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.1 EJS43473.1 - 0.13 11.7 0.1 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AD PF09793.4 EJS43474.1 - 7.9e-28 96.1 0.3 1.2e-27 95.5 0.2 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Peroxin-22 PF12827.2 EJS43474.1 - 0.12 12.1 1.9 0.16 11.7 1.3 1.5 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family LSM14 PF12701.2 EJS43474.1 - 0.23 11.3 2.2 0.39 10.5 0.3 2.4 2 2 0 2 2 2 0 Scd6-like Sm domain DUF59 PF01883.14 EJS43475.1 - 1.1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF59 NDT80_PhoG PF05224.7 EJS43476.1 - 3.9e-69 232.3 0.1 7.6e-69 231.4 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family PIR PF00399.14 EJS43477.1 - 4.2e-06 25.9 10.2 4.2e-06 25.9 7.1 1.8 2 0 0 2 2 2 1 Yeast PIR protein repeat RRM_1 PF00076.17 EJS43478.1 - 0.025 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPRTase PF14681.1 EJS43479.1 - 6.1e-77 257.4 0.0 7.2e-77 257.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EJS43479.1 - 0.0047 16.6 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EJS43479.1 - 0.072 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.14 EJS43480.1 - 1.2e-112 376.2 0.0 1.4e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EJS43480.1 - 0.074 11.6 0.0 2.9 6.4 0.0 2.5 2 1 0 2 2 2 0 MreB/Mbl protein Peptidase_M14 PF00246.19 EJS43481.1 - 2.9e-72 243.6 0.0 3.5e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Endosulfine PF04667.12 EJS43482.1 - 3.8e-34 116.4 0.1 5.1e-34 116.0 0.1 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Act-Frag_cataly PF09192.5 EJS43482.1 - 0.066 12.1 0.0 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic INSIG PF07281.7 EJS43483.1 - 4.4e-14 52.2 1.9 8.1e-14 51.3 1.3 1.5 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) Thia_YuaJ PF09515.5 EJS43483.1 - 0.61 9.8 8.2 1.2 8.8 2.5 2.3 2 0 0 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) WLM PF08325.5 EJS43484.1 - 6e-55 186.0 0.0 7.5e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EJS43484.1 - 0.0037 17.0 0.3 0.0071 16.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function DUF45 Pkinase PF00069.20 EJS43485.1 - 3.4e-33 114.8 0.0 3.4e-33 114.8 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43485.1 - 7.2e-13 48.2 0.1 1.7e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RRM_1 PF00076.17 EJS43486.1 - 9.1e-36 121.3 12.4 2.2e-14 52.8 0.0 4.2 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS43486.1 - 8.1e-30 102.6 0.1 3.4e-10 39.7 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS43486.1 - 3.4e-19 68.4 1.8 2.5e-05 24.0 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EJS43486.1 - 0.00013 21.6 0.2 3.2 7.5 0.0 4.0 3 1 0 3 3 3 2 Limkain b1 Radical_SAM PF04055.16 EJS43486.1 - 0.024 14.8 0.1 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Radical SAM superfamily Lyase_1 PF00206.15 EJS43487.1 - 1.9e-96 322.9 0.0 2.6e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EJS43487.1 - 1.6e-26 92.1 0.0 4.4e-26 90.7 0.0 1.8 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal tRNA-synt_2 PF00152.15 EJS43488.1 - 1.2e-74 251.0 0.0 1.9e-74 250.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EJS43488.1 - 2.7e-13 49.5 0.0 5.8e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.6 EJS43488.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase tRNA_anti-like PF12869.2 EJS43488.1 - 0.065 12.7 0.4 0.13 11.7 0.3 1.5 1 0 0 1 1 1 0 tRNA_anti-like ProRS-C_1 PF09180.6 EJS43489.1 - 3.9e-25 87.5 1.3 8.3e-25 86.4 0.9 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EJS43489.1 - 2.8e-22 79.0 0.0 4.9e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EJS43489.1 - 2.7e-18 65.6 0.1 6.4e-18 64.4 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain Peptidase_M16_C PF05193.16 EJS43490.1 - 1.3e-45 155.3 0.0 2.5e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EJS43490.1 - 2.7e-45 153.7 0.0 1.4e-42 144.9 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) GP11 PF08677.5 EJS43490.1 - 0.05 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 GP11 baseplate wedge protein ATP-synt_C PF00137.16 EJS43491.1 - 7.5e-28 96.2 28.5 1.3e-18 66.6 5.7 2.4 2 0 0 2 2 2 2 ATP synthase subunit C Form_Nir_trans PF01226.12 EJS43492.1 - 2.5e-67 226.3 21.2 3.1e-67 226.1 14.7 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Pkinase PF00069.20 EJS43493.1 - 7.9e-73 244.7 0.0 1.4e-72 243.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43493.1 - 1.6e-47 161.7 0.0 3e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EJS43493.1 - 8.5e-22 77.3 3.0 2.2e-21 76.0 0.0 3.5 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 EJS43493.1 - 0.00021 20.3 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ANAPC15 PF15243.1 EJS43493.1 - 0.0078 16.2 7.2 0.0088 16.0 3.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 15 APH PF01636.18 EJS43493.1 - 0.13 12.0 0.0 0.94 9.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S2 PF00318.15 EJS43494.1 - 4.3e-61 205.8 0.0 1.4e-60 204.1 0.0 1.9 2 1 1 3 3 3 1 Ribosomal protein S2 TRAM_LAG1_CLN8 PF03798.11 EJS43495.1 - 1.7e-34 119.0 25.5 1.7e-34 119.0 17.7 2.6 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EJS43495.1 - 3.2e-24 84.1 3.5 3.2e-24 84.1 2.4 2.1 2 0 0 2 2 2 1 TRAM1-like protein Oxysterol_BP PF01237.13 EJS43496.1 - 1.7e-90 303.0 0.0 2.1e-90 302.7 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein ThiF PF00899.16 EJS43497.1 - 7.9e-35 119.6 0.1 1.9e-34 118.3 0.0 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 EJS43497.1 - 0.00013 22.0 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EJS43497.1 - 0.001 19.0 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 EJS43497.1 - 0.0069 16.6 0.0 0.024 14.8 0.0 1.9 1 0 0 1 1 1 1 Putative NAD(P)-binding ApbA PF02558.11 EJS43497.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_17 PF00332.13 EJS43497.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 NIF PF03031.13 EJS43498.1 - 3.2e-52 176.3 0.0 5.3e-52 175.6 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase G-alpha PF00503.15 EJS43499.1 - 4.5e-124 414.0 7.8 5.8e-124 413.7 5.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EJS43499.1 - 5.1e-16 58.4 0.6 9.6e-11 41.2 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EJS43499.1 - 0.00028 21.3 0.1 0.37 11.3 0.0 3.1 3 0 0 3 3 3 2 Miro-like protein Gtr1_RagA PF04670.7 EJS43499.1 - 0.00036 19.7 0.3 0.07 12.2 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region PPO1_KFDV PF12143.3 EJS43499.1 - 0.015 15.1 0.1 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) Drf_GBD PF06371.8 EJS43499.1 - 0.018 14.3 0.7 1.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain AAA_22 PF13401.1 EJS43499.1 - 0.037 14.1 0.6 0.8 9.8 0.4 2.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EJS43499.1 - 0.043 13.2 0.0 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EJS43499.1 - 0.073 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EJS43499.1 - 0.079 12.9 0.0 13 5.7 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase zf-Tim10_DDP PF02953.10 EJS43500.1 - 4.2e-24 83.6 4.3 5.1e-24 83.3 3.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EJS43500.1 - 0.014 14.8 3.3 0.018 14.5 2.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Tom5 PF10642.4 EJS43500.1 - 0.024 14.2 0.9 0.049 13.2 0.7 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase zf-C2H2 PF00096.21 EJS43501.1 - 9e-06 25.7 12.3 0.00046 20.3 1.7 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS43501.1 - 0.0011 19.1 12.2 0.0073 16.5 1.0 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EJS43501.1 - 0.0067 16.6 9.0 0.069 13.4 0.5 3.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EJS43501.1 - 0.008 16.2 7.8 5.6 7.2 0.1 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding p450 PF00067.17 EJS43502.1 - 1.8e-114 382.8 0.0 2e-114 382.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol_B_palm PF14792.1 EJS43502.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm Sod_Fe_C PF02777.13 EJS43503.1 - 1e-37 128.1 0.1 2.2e-37 127.1 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EJS43503.1 - 1.2e-24 86.3 0.6 2.5e-24 85.3 0.4 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 EJS43503.1 - 0.033 13.2 0.2 0.38 9.8 0.0 2.5 3 0 0 3 3 3 0 Immunity protein 15 HHH_2 PF12826.2 EJS43503.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DAO PF01266.19 EJS43504.1 - 2.1e-78 263.7 0.0 4.9e-78 262.5 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EJS43504.1 - 5e-07 29.6 0.1 1.5e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EJS43504.1 - 0.00053 18.7 0.1 0.014 14.0 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 EJS43504.1 - 0.0038 17.6 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EJS43504.1 - 0.017 14.1 0.1 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EJS43504.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Strep_67kDa_ant PF06100.6 EJS43504.1 - 0.12 10.6 0.1 0.2 9.9 0.1 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family tRNA-synt_2b PF00587.20 EJS43505.1 - 3.3e-24 85.3 0.0 4.9e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EJS43505.1 - 9e-07 28.8 6.4 2e-06 27.7 4.5 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 EJS43505.1 - 0.0019 18.1 4.6 0.0039 17.0 3.2 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF724 PF05266.9 EJS43505.1 - 0.0062 16.1 2.2 0.011 15.4 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) IncA PF04156.9 EJS43505.1 - 0.014 15.0 4.2 0.021 14.3 2.9 1.4 1 0 0 1 1 1 0 IncA protein DUF641 PF04859.7 EJS43505.1 - 0.018 14.7 3.7 0.036 13.8 2.6 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Laminin_II PF06009.7 EJS43505.1 - 0.019 14.7 0.5 0.039 13.7 0.3 1.5 1 0 0 1 1 1 0 Laminin Domain II Spc7 PF08317.6 EJS43505.1 - 0.027 13.1 6.3 0.043 12.4 4.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.5 EJS43505.1 - 0.039 14.0 6.4 0.12 12.5 4.4 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 EJS43505.1 - 0.051 12.7 0.1 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EJS43505.1 - 0.074 12.8 2.4 0.058 13.2 0.4 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 EJS43505.1 - 0.14 11.0 6.0 0.24 10.2 4.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 EJS43505.1 - 0.4 9.5 3.1 6.7 5.5 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.6 EJS43505.1 - 0.8 9.1 10.3 0.23 10.8 2.0 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 EJS43505.1 - 1.5 8.6 9.2 4.4 7.1 6.4 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AAA_23 PF13476.1 EJS43505.1 - 5.5 7.2 10.6 11 6.2 7.3 1.5 1 0 0 1 1 1 0 AAA domain DivIC PF04977.10 EJS43505.1 - 8.1 6.0 11.2 17 4.9 3.3 2.8 1 1 1 2 2 2 0 Septum formation initiator Acetyltransf_1 PF00583.19 EJS43506.1 - 1.2e-16 60.5 0.0 1.8e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EJS43506.1 - 2.3e-05 24.0 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EJS43506.1 - 5.6e-05 23.2 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EJS43506.1 - 0.0042 17.1 0.0 0.0083 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EJS43506.1 - 0.0049 17.0 0.0 0.0068 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EJS43506.1 - 0.023 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EJS43506.1 - 0.024 14.2 0.1 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain V-SNARE_C PF12352.3 EJS43508.1 - 7.6e-20 70.7 1.7 7.6e-20 70.7 1.2 2.3 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus BLOC1_2 PF10046.4 EJS43508.1 - 0.015 15.4 5.9 2 8.5 0.2 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec20 PF03908.8 EJS43508.1 - 0.046 13.4 0.5 0.046 13.4 0.3 2.9 2 1 1 3 3 3 0 Sec20 Arteri_nucleo PF01481.11 EJS43508.1 - 0.058 13.4 2.3 1.1 9.3 0.0 2.7 3 1 0 3 3 3 0 Arterivirus nucleocapsid protein ERp29 PF07749.7 EJS43508.1 - 0.075 13.6 1.2 4.2 8.0 0.0 3.2 1 1 2 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain RseA_N PF03872.8 EJS43508.1 - 0.082 13.2 0.4 0.18 12.1 0.2 1.7 1 1 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain TBPIP PF07106.8 EJS43508.1 - 0.54 9.7 5.6 2.9 7.3 1.5 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sec34 PF04136.10 EJS43508.1 - 0.56 9.8 6.7 0.23 11.1 1.2 2.4 1 1 1 3 3 3 0 Sec34-like family V_ATPase_I PF01496.14 EJS43508.1 - 0.74 7.5 6.1 0.042 11.7 0.9 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family WXG100 PF06013.7 EJS43508.1 - 1.2 9.2 8.2 5.6 7.0 0.0 3.5 2 1 2 4 4 4 0 Proteins of 100 residues with WXG TACC PF05010.9 EJS43508.1 - 1.6 8.4 7.2 2.6 7.7 0.0 2.4 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) IncA PF04156.9 EJS43508.1 - 3 7.3 11.3 14 5.2 7.6 2.2 1 1 0 1 1 1 0 IncA protein PMC2NT PF08066.7 EJS43508.1 - 4.6 7.5 6.1 4.7 7.5 0.2 2.8 1 1 3 4 4 4 0 PMC2NT (NUC016) domain Ecm29 PF13001.2 EJS43509.1 - 6.7e-126 420.7 7.0 2.9e-125 418.6 4.8 2.2 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 EJS43509.1 - 5.6e-16 57.1 8.4 0.0008 19.2 0.0 8.1 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EJS43509.1 - 3e-06 27.5 2.5 2 9.0 0.0 7.0 6 1 1 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.1 EJS43509.1 - 1.2e-05 25.4 0.3 6.3 7.1 0.1 6.4 7 1 0 7 7 7 1 HEAT repeats Ipi1_N PF12333.3 EJS43509.1 - 1.3 8.9 7.9 0.77 9.7 0.1 4.8 6 1 0 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation zf-C2H2 PF00096.21 EJS43510.1 - 4e-07 29.9 21.7 0.00021 21.4 1.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EJS43510.1 - 0.014 15.6 9.8 0.016 15.4 1.9 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EJS43510.1 - 0.015 15.4 0.8 0.08 13.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EJS43510.1 - 0.031 14.4 0.3 0.031 14.4 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EJS43510.1 - 0.1 12.9 0.4 0.1 12.9 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger RRM_1 PF00076.17 EJS43512.1 - 1.8e-27 94.7 0.7 2.2e-14 52.8 0.1 3.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS43512.1 - 2e-18 65.9 0.5 4.6e-08 32.7 0.1 3.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS43512.1 - 5.3e-15 55.1 0.2 4.3e-07 29.8 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EJS43512.1 - 4.5e-05 23.2 0.2 0.0052 16.6 0.1 2.4 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EJS43512.1 - 0.02 14.6 0.1 2.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF386 PF04074.7 EJS43512.1 - 0.054 13.0 0.8 0.11 12.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF386) Adenyl_cycl_N PF12633.2 EJS43512.1 - 0.063 12.8 0.2 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase NT domain NPR3 PF03666.8 EJS43513.1 - 7.9e-150 499.3 7.3 7.9e-150 499.3 5.0 3.4 3 1 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 TauD PF02668.11 EJS43514.1 - 1.9e-40 139.2 0.0 3.1e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EJS43514.1 - 0.092 13.1 0.0 0.65 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF971) Adap_comp_sub PF00928.16 EJS43515.1 - 3.7e-66 222.9 3.5 3.7e-66 222.9 2.4 1.6 2 1 0 2 2 2 1 Adaptor complexes medium subunit family Voldacs PF03517.8 EJS43515.1 - 2.7 7.8 8.7 0.3 10.9 0.8 2.4 1 1 0 2 2 2 0 Regulator of volume decrease after cellular swelling Lung_7-TM_R PF06814.8 EJS43516.1 - 1.7e-88 296.4 31.9 2e-88 296.1 22.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor TMEM154 PF15102.1 EJS43516.1 - 0.17 11.5 0.3 21 4.7 0.1 3.1 3 0 0 3 3 3 0 TMEM154 protein family GpcrRhopsn4 PF10192.4 EJS43516.1 - 9.4 5.3 39.5 0.5 9.5 19.0 2.2 1 1 1 2 2 2 0 Rhodopsin-like GPCR transmembrane domain SSF PF00474.12 EJS43517.1 - 9.7e-18 63.9 29.3 1.6e-17 63.2 20.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family FixP_N PF14715.1 EJS43517.1 - 0.41 10.0 4.1 12 5.4 0.0 3.4 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Ribosomal_S10 PF00338.17 EJS43518.1 - 2.1e-27 94.7 1.5 2.6e-27 94.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4320 PF14208.1 EJS43518.1 - 0.0094 15.8 0.1 0.014 15.3 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4320) Retrotrans_gag PF03732.12 EJS43518.1 - 0.093 12.8 0.2 0.18 11.9 0.0 1.6 2 1 0 2 2 2 0 Retrotransposon gag protein OTU PF02338.14 EJS43519.1 - 4.3e-22 78.9 0.1 4.3e-22 78.9 0.0 2.1 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EJS43519.1 - 3.8e-05 23.1 9.8 9.8e-05 21.8 0.0 3.3 1 1 1 3 3 3 2 Peptidase C65 Otubain Pribosyl_synth PF14572.1 EJS43520.1 - 1.2e-41 142.4 2.9 4.2e-36 124.4 1.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EJS43520.1 - 3e-37 126.9 0.6 1.4e-36 124.7 0.0 2.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EJS43520.1 - 2.2e-11 43.5 0.9 7.7e-11 41.8 0.7 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EJS43520.1 - 0.021 14.0 0.2 0.033 13.4 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 EJS43520.1 - 0.11 12.1 0.9 0.25 11.0 0.6 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C BRAP2 PF07576.7 EJS43521.1 - 1.7e-34 117.6 4.4 1e-32 111.9 0.8 2.5 2 0 0 2 2 2 2 BRCA1-associated protein 2 zf-UBP PF02148.14 EJS43521.1 - 1e-21 76.8 6.4 1e-21 76.8 4.4 1.8 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EJS43521.1 - 3.3e-10 39.6 11.1 3.3e-10 39.6 7.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EJS43521.1 - 1.1e-05 25.0 11.0 1.1e-05 25.0 7.6 2.3 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EJS43521.1 - 2e-05 24.4 10.8 2e-05 24.4 7.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EJS43521.1 - 4.5e-05 23.0 6.1 0.00026 20.6 4.3 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EJS43521.1 - 5e-05 22.8 10.8 0.00014 21.4 7.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EJS43521.1 - 6.4e-05 22.9 5.2 6.4e-05 22.9 3.6 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EJS43521.1 - 0.0016 18.1 4.6 0.0046 16.7 3.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EJS43521.1 - 0.0022 17.5 7.9 0.0056 16.2 5.5 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EJS43521.1 - 0.01 15.6 1.3 0.033 14.0 0.9 1.8 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain IncA PF04156.9 EJS43521.1 - 0.45 10.0 22.8 0.44 10.1 11.1 2.3 1 1 1 2 2 2 0 IncA protein Rad50_zn_hook PF04423.9 EJS43521.1 - 0.74 9.3 5.3 10 5.6 0.1 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.1 EJS43521.1 - 3.8 7.1 10.5 24 4.5 4.1 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 bZIP_1 PF00170.16 EJS43522.1 - 4.5e-07 29.7 16.9 4.5e-07 29.7 11.7 1.9 2 0 0 2 2 2 1 bZIP transcription factor V_ATPase_I PF01496.14 EJS43522.1 - 0.054 11.3 8.0 0.025 12.4 3.9 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family RIC3 PF15361.1 EJS43522.1 - 0.082 13.1 0.7 0.2 11.9 0.5 1.7 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Glutaredoxin2_C PF04399.8 EJS43522.1 - 0.25 10.9 7.0 0.064 12.8 2.6 1.6 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DUF1875 PF08961.5 EJS43522.1 - 0.35 10.1 7.9 0.25 10.6 2.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1875) bZIP_2 PF07716.10 EJS43522.1 - 0.51 10.2 18.5 0.28 11.0 10.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF349 PF03993.7 EJS43522.1 - 0.86 9.8 9.6 2.1 8.5 6.6 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) IncA PF04156.9 EJS43522.1 - 6.1 6.3 13.3 1.2 8.6 5.5 2.0 2 0 0 2 2 2 0 IncA protein DUF507 PF04368.8 EJS43523.1 - 0.00096 18.8 2.0 0.0018 17.9 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF507) SET PF00856.23 EJS43523.1 - 0.043 14.1 0.1 0.097 12.9 0.1 1.6 1 0 0 1 1 1 0 SET domain RRM_1 PF00076.17 EJS43525.1 - 9.5e-19 66.8 6.2 9.8e-13 47.5 0.1 3.5 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS43525.1 - 3.2e-09 36.6 1.2 0.00026 20.8 0.1 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FctA PF12892.2 EJS43525.1 - 0.5 11.1 3.3 0.4 11.5 0.8 2.0 2 0 0 2 2 2 0 T surface-antigen of pili DUP PF00674.13 EJS43526.1 - 4.1e-29 100.7 3.6 5.3e-29 100.3 2.5 1.2 1 0 0 1 1 1 1 DUP family Epimerase PF01370.16 EJS43527.1 - 6.8e-16 58.4 0.1 2e-15 56.8 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EJS43527.1 - 3.3e-10 39.1 0.1 4.1e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EJS43527.1 - 3.2e-08 33.7 0.0 5.5e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EJS43527.1 - 4.8e-07 28.9 0.1 2.3e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EJS43527.1 - 8.8e-06 25.7 0.0 2.6e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EJS43527.1 - 2.4e-05 23.7 0.0 0.00033 19.9 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EJS43527.1 - 0.00072 19.2 0.0 0.0017 18.0 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EJS43527.1 - 0.00081 18.3 0.0 0.0019 17.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF1507 PF07408.6 EJS43527.1 - 0.039 13.7 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) F420_oxidored PF03807.12 EJS43527.1 - 0.12 12.7 0.0 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 EJS43528.1 - 2.9e-69 233.1 0.1 7.9e-69 231.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43528.1 - 2.5e-30 105.4 0.0 3.7e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EJS43528.1 - 5.4e-11 42.8 2.0 5.4e-11 42.8 1.4 2.9 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 EJS43528.1 - 7.4e-10 38.2 0.0 1.9e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 EJS43528.1 - 3.9e-06 26.6 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 C2 domain YrbL-PhoP_reg PF10707.4 EJS43528.1 - 0.059 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EJS43528.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SET PF00856.23 EJS43529.1 - 5.5e-13 49.5 0.9 3.9e-12 46.7 0.6 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EJS43529.1 - 0.017 15.0 7.2 0.017 15.0 5.0 3.5 3 1 1 4 4 4 0 MYND finger Myticin-prepro PF10690.4 EJS43529.1 - 5.1 7.1 9.3 8.2 6.5 0.0 3.3 2 1 0 3 3 3 0 Myticin pre-proprotein from the mussel Aminotran_4 PF01063.14 EJS43530.1 - 2.3e-29 102.5 0.0 2.8e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Methyltransf_11 PF08241.7 EJS43531.1 - 5.3e-16 58.8 0.0 9.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS43531.1 - 1e-13 51.8 0.0 1.9e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EJS43531.1 - 6.7e-12 45.7 0.0 1.7e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EJS43531.1 - 5.9e-11 42.1 0.0 9.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EJS43531.1 - 6.7e-11 42.4 0.0 3.7e-10 40.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EJS43531.1 - 3.7e-10 39.7 0.0 8e-10 38.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EJS43531.1 - 2.8e-06 26.6 0.0 4.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EJS43531.1 - 7.7e-05 22.7 0.0 0.00023 21.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EJS43531.1 - 0.0019 17.3 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EJS43531.1 - 0.013 15.1 0.0 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.5 EJS43531.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GxGYxYP PF14323.1 EJS43531.1 - 0.035 12.8 0.1 0.052 12.2 0.1 1.2 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function MTS PF05175.9 EJS43531.1 - 0.091 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain SKN1 PF03935.10 EJS43532.1 - 1.6e-256 851.2 5.9 2.1e-256 850.8 4.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) NUC153 PF08159.7 EJS43533.1 - 3.9e-13 48.7 6.8 8.7e-13 47.6 4.7 1.7 1 0 0 1 1 1 1 NUC153 domain DUF4658 PF15555.1 EJS43533.1 - 0.62 9.9 2.7 1.5 8.7 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) DUF1279 PF06916.8 EJS43534.1 - 2.3e-21 75.8 0.0 5.5e-21 74.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L24e PF01246.15 EJS43535.1 - 5.4e-33 112.6 0.4 5.4e-33 112.6 0.3 2.0 2 1 0 2 2 2 1 Ribosomal protein L24e DUF2838 PF10998.3 EJS43536.1 - 1.4e-44 150.5 16.6 1.4e-44 150.5 11.5 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF2838) Pox_A_type_inc PF04508.7 EJS43536.1 - 0.27 11.1 1.4 3.6 7.6 0.3 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PPR_2 PF13041.1 EJS43537.1 - 2.9e-14 52.7 1.8 4.4e-09 36.1 0.0 3.3 3 1 1 4 4 4 2 PPR repeat family PPR PF01535.15 EJS43537.1 - 1.9e-09 36.8 0.0 9.6e-06 25.2 0.0 4.0 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 EJS43537.1 - 9e-08 31.8 0.9 0.002 18.2 0.0 5.1 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 EJS43537.1 - 0.0022 17.4 0.0 0.12 11.8 0.0 2.7 2 0 0 2 2 2 1 PPR repeat Ras PF00071.17 EJS43538.1 - 2.2e-50 170.2 0.0 3.5e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS43538.1 - 7.2e-18 65.2 0.3 1.9e-17 63.8 0.0 1.8 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EJS43538.1 - 6.9e-08 31.9 0.1 9e-08 31.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EJS43538.1 - 1.7e-07 30.8 0.0 3.3e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EJS43538.1 - 0.002 18.0 0.0 0.0054 16.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Neur_chan_memb PF02932.11 EJS43538.1 - 4.2 7.1 7.9 5.8 6.7 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol_3_Rpc31 PF11705.3 EJS43539.1 - 0.042 13.7 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TA0956 PF11513.3 EJS43539.1 - 0.057 13.4 0.3 0.39 10.8 0.1 2.0 1 1 1 2 2 2 0 Thermoplasma acidophilum protein TA0956 GST_N_2 PF13409.1 EJS43540.1 - 2.2e-16 59.5 0.0 6.4e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EJS43540.1 - 1.4e-07 31.2 0.0 3.3e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EJS43540.1 - 0.0011 19.4 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EJS43540.1 - 0.0049 17.0 0.0 0.75 10.0 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain PALP PF00291.20 EJS43541.1 - 1.6e-57 195.0 0.0 1.9e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EJS43541.1 - 1.1e-15 57.1 0.0 5.4e-11 42.1 0.1 2.6 2 0 0 2 2 2 2 CBS domain GHMP_kinases_C PF08544.8 EJS43541.1 - 0.03 14.5 0.0 0.95 9.7 0.0 2.8 3 0 0 3 3 3 0 GHMP kinases C terminal CSTF2_hinge PF14327.1 EJS43542.1 - 2.2e-25 88.5 2.1 2.2e-25 88.5 1.5 2.9 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 APG5 PF04106.7 EJS43542.1 - 0.007 15.8 0.2 0.021 14.2 0.2 1.8 1 0 0 1 1 1 1 Autophagy protein Apg5 CSTF_C PF14304.1 EJS43542.1 - 0.012 14.8 5.4 0.024 13.9 0.6 3.2 3 0 0 3 3 3 0 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.17 EJS43542.1 - 0.016 14.8 0.0 0.054 13.1 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MarR PF01047.17 EJS43542.1 - 0.022 14.4 0.1 0.05 13.3 0.1 1.6 1 0 0 1 1 1 0 MarR family RRM_6 PF14259.1 EJS43542.1 - 0.038 13.9 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PEMT PF04191.8 EJS43543.1 - 2.1e-54 182.1 8.7 1.4e-32 111.9 0.9 4.4 5 0 0 5 5 5 2 Phospholipid methyltransferase SinI PF08671.5 EJS43543.1 - 0.067 12.6 0.2 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Anti-repressor SinI DUF2046 PF09755.4 EJS43544.1 - 0.0034 16.3 0.1 0.0054 15.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) MerR_2 PF13591.1 EJS43544.1 - 0.041 13.4 0.8 0.071 12.7 0.6 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein Uso1_p115_C PF04871.8 EJS43544.1 - 0.049 13.5 0.1 0.069 13.0 0.1 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CCDC92 PF14916.1 EJS43544.1 - 0.088 12.4 0.5 0.23 11.0 0.3 1.7 2 0 0 2 2 2 0 Coiled-coil domain of unknown function MIF4G PF02854.14 EJS43546.1 - 3.7e-49 166.9 0.0 6.4e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EJS43546.1 - 1.5e-27 95.2 0.1 7.6e-27 93.0 0.0 2.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Gtr1_RagA PF04670.7 EJS43547.1 - 5.3e-69 231.8 1.4 6.8e-69 231.5 0.9 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 EJS43547.1 - 0.00054 19.8 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EJS43547.1 - 0.0067 15.3 0.0 0.019 13.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EJS43547.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase SRPRB PF09439.5 EJS43547.1 - 0.031 13.5 0.1 0.079 12.1 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.16 EJS43547.1 - 0.062 12.5 0.1 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 EJS43547.1 - 0.066 13.7 0.1 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein Bot1p PF12298.3 EJS43548.1 - 1.7e-58 197.3 0.1 2.3e-58 196.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein HTH_37 PF13744.1 EJS43548.1 - 0.14 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Trs65 PF12735.2 EJS43549.1 - 2.9e-58 197.6 10.5 2.9e-58 197.6 7.3 2.0 2 1 0 2 2 2 1 TRAPP trafficking subunit Trs65 Clathrin_lg_ch PF01086.12 EJS43550.1 - 6.4e-61 206.1 24.6 7.3e-61 205.9 17.1 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF2201_N PF13203.1 EJS43550.1 - 0.91 8.6 6.3 1.1 8.3 4.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain PseudoU_synth_2 PF00849.17 EJS43551.1 - 5.4e-25 88.1 0.0 9.1e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase F-protein PF00469.15 EJS43552.1 - 1.2 8.5 10.7 1.3 8.3 7.4 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF4355 PF14265.1 EJS43552.1 - 3 7.7 24.9 4 7.4 17.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF1764 PF08576.5 EJS43552.1 - 5.5 7.8 13.0 7 7.4 9.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Sec62 PF03839.11 EJS43552.1 - 9.8 5.5 13.4 10 5.4 9.3 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 BTV_NS2 PF04514.7 EJS43552.1 - 9.8 4.9 12.1 11 4.7 8.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PS_Dcarbxylase PF02666.10 EJS43553.1 - 9.3e-52 175.2 0.0 1.5e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EJS43553.1 - 1e-15 57.3 3.7 3.3e-09 36.4 0.1 3.0 2 0 0 2 2 2 2 C2 domain Yip1 PF04893.12 EJS43554.1 - 1.3e-12 47.5 15.1 1.9e-12 47.0 10.5 1.3 1 0 0 1 1 1 1 Yip1 domain MMR_HSR1 PF01926.18 EJS43555.1 - 7.8e-20 70.9 0.5 2.2e-19 69.5 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 EJS43555.1 - 3.5e-18 65.1 0.1 8.6e-18 63.9 0.0 1.8 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.13 EJS43555.1 - 1.9e-13 49.9 0.0 3.2e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EJS43555.1 - 7.5e-05 22.6 0.5 0.029 14.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EJS43555.1 - 0.00022 21.6 0.1 0.00089 19.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 EJS43555.1 - 0.0011 18.0 0.1 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 EJS43555.1 - 0.0083 15.3 0.7 0.03 13.5 0.1 2.1 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MCM PF00493.18 EJS43555.1 - 0.016 14.0 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family Ras PF00071.17 EJS43555.1 - 0.036 13.4 0.5 0.94 8.8 0.0 2.3 2 0 0 2 2 2 0 Ras family RHH_3 PF12651.2 EJS43555.1 - 0.089 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain SE PF08491.5 EJS43556.1 - 7.6e-124 411.9 0.0 9.8e-124 411.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EJS43556.1 - 1.5e-13 50.5 0.0 2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EJS43556.1 - 2e-07 30.2 0.1 3.5e-05 22.8 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EJS43556.1 - 0.001 18.9 0.2 0.002 18.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EJS43556.1 - 0.0017 18.7 0.2 0.0054 17.1 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EJS43556.1 - 0.0046 16.9 0.1 0.01 15.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EJS43556.1 - 0.0068 15.3 1.2 0.015 14.1 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 EJS43556.1 - 0.0081 15.8 0.2 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EJS43556.1 - 0.013 14.5 0.1 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family GDI PF00996.13 EJS43556.1 - 0.022 13.1 0.0 0.037 12.3 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Shikimate_DH PF01488.15 EJS43556.1 - 0.024 14.7 0.1 0.045 13.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EJS43556.1 - 0.12 11.8 0.1 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EJS43556.1 - 0.13 11.6 0.3 0.32 10.3 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EJS43556.1 - 0.13 10.7 0.6 0.55 8.6 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 EJS43556.1 - 0.14 11.2 0.6 0.29 10.1 0.4 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EJS43556.1 - 2.6 6.8 3.8 3.7 6.3 0.2 2.5 3 1 0 3 3 3 0 Lycopene cyclase protein LsmAD PF06741.8 EJS43557.1 - 1.7e-30 104.9 0.2 1.7e-30 104.9 0.2 2.4 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EJS43557.1 - 1.4e-16 60.1 0.1 3.7e-16 58.8 0.1 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain Bap31 PF05529.7 EJS43557.1 - 8.5 5.7 5.7 1.1 8.6 1.1 1.7 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Ribonuc_red_sm PF00268.16 EJS43558.1 - 6.6e-76 254.9 4.4 7.9e-76 254.7 3.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain zf-Tim10_DDP PF02953.10 EJS43559.1 - 5.3e-19 67.2 0.6 8e-19 66.7 0.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 EJS43559.1 - 0.075 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) Myb_DNA-bind_6 PF13921.1 EJS43559.1 - 0.14 12.2 0.3 2.4 8.3 0.0 2.2 1 1 0 2 2 2 0 Myb-like DNA-binding domain zf-UBR PF02207.15 EJS43560.1 - 4.5e-15 55.1 16.3 4.5e-15 55.1 11.3 2.9 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EJS43560.1 - 1.3e-07 31.2 0.0 3.1e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS tRNA-synt_1b PF00579.20 EJS43561.1 - 8.1e-77 258.2 0.0 1e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Tup_N PF08581.5 EJS43561.1 - 0.13 12.5 0.0 0.9 9.7 0.0 2.3 2 0 0 2 2 2 0 Tup N-terminal Mad3_BUB1_I PF08311.7 EJS43562.1 - 2.1e-35 121.2 1.6 4.6e-35 120.1 1.1 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 EJS43562.1 - 4.4e-26 90.5 0.1 1.8e-25 88.6 0.0 2.1 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.20 EJS43562.1 - 3e-16 59.3 0.0 5.7e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43562.1 - 0.0028 16.7 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_16 PF00722.16 EJS43563.1 - 2.4e-46 157.3 3.1 2.4e-46 157.3 2.2 3.5 2 1 0 3 3 3 1 Glycosyl hydrolases family 16 DUF605 PF04652.11 EJS43563.1 - 0.28 10.5 41.6 0.45 9.8 28.8 1.2 1 0 0 1 1 1 0 Vta1 like AA_permease PF00324.16 EJS43564.1 - 1.2e-135 452.5 35.3 1.4e-135 452.3 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS43564.1 - 1e-37 129.6 37.2 1.3e-37 129.3 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease Gp_dh_C PF02800.15 EJS43565.1 - 3.9e-74 247.3 0.1 6.1e-74 246.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EJS43565.1 - 5.8e-59 198.3 0.1 1.1e-58 197.5 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EJS43565.1 - 0.0083 16.0 1.6 0.013 15.3 0.2 2.2 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EJS43565.1 - 0.071 12.2 0.1 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Biotin_lipoyl PF00364.17 EJS43566.1 - 1.1e-19 69.8 0.2 2.1e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EJS43566.1 - 8.3e-05 22.1 0.0 0.00019 20.9 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EJS43566.1 - 0.016 14.8 0.6 0.12 12.0 0.0 2.7 2 1 1 3 3 3 0 Biotin-lipoyl like HlyD_3 PF13437.1 EJS43566.1 - 0.059 13.7 2.8 0.84 10.0 0.0 3.1 2 1 1 3 3 3 0 HlyD family secretion protein RNase_PH PF01138.16 EJS43567.1 - 2.3e-25 89.4 0.0 3.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EJS43567.1 - 3.7e-06 26.7 0.1 9.3e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 YgaB PF14182.1 EJS43567.1 - 0.07 13.3 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 YgaB-like protein WD40 PF00400.27 EJS43568.1 - 5.8e-64 209.8 18.2 3.3e-11 42.6 0.0 11.2 12 0 0 12 12 12 10 WD domain, G-beta repeat CTP_transf_2 PF01467.21 EJS43569.1 - 2.2e-24 86.3 0.0 4e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase IncA PF04156.9 EJS43569.1 - 0.086 12.4 4.9 4 6.9 0.8 2.3 2 0 0 2 2 2 0 IncA protein Rhodanese PF00581.15 EJS43570.1 - 8.1e-10 39.0 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain FTHFS PF01268.14 EJS43571.1 - 6.6e-256 849.6 1.2 6.6e-256 849.6 0.8 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EJS43571.1 - 1.8e-60 202.6 2.7 2e-60 202.5 0.2 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EJS43571.1 - 2.1e-39 134.1 0.1 1.6e-38 131.3 0.0 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AAA_17 PF13207.1 EJS43572.1 - 0.00089 20.0 0.0 0.0014 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EJS43572.1 - 0.0049 16.7 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EJS43572.1 - 0.0058 16.9 0.0 0.013 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EJS43572.1 - 0.0077 15.6 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EJS43572.1 - 0.011 15.8 0.0 0.046 13.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 EJS43572.1 - 0.051 13.5 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EJS43572.1 - 0.056 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 EJS43572.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EJS43572.1 - 0.073 12.4 0.0 0.38 10.1 0.1 1.8 1 1 0 2 2 2 0 AAA-like domain PIF1 PF05970.9 EJS43572.1 - 0.094 11.6 0.1 0.3 10.0 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase AAA_33 PF13671.1 EJS43572.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain TRAPPC-Trs85 PF12739.2 EJS43572.1 - 0.17 10.5 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Mvb12 PF09452.5 EJS43573.1 - 1.6e-39 133.9 0.4 1.8e-39 133.8 0.3 1.0 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 ETF PF01012.16 EJS43574.1 - 2.4e-35 121.7 0.0 2.9e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain HAD PF12710.2 EJS43575.1 - 5.5e-13 49.5 0.1 8.7e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EJS43575.1 - 7.9e-12 46.0 0.2 3.4e-11 43.9 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EJS43575.1 - 1.1e-07 31.7 4.3 1.9e-06 27.6 0.0 3.2 1 1 2 3 3 3 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EJS43575.1 - 4.4e-05 22.7 0.3 4.4e-05 22.7 0.2 1.9 2 1 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.1 EJS43575.1 - 0.00017 21.8 0.1 0.00038 20.7 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EJS43575.1 - 0.046 13.3 0.3 0.37 10.4 0.0 2.4 2 1 0 2 2 2 0 Acid Phosphatase Thioredoxin PF00085.15 EJS43576.1 - 1.9e-32 111.0 0.1 2.2e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EJS43576.1 - 6.9e-10 39.1 0.2 8.9e-09 35.5 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EJS43576.1 - 9.5e-08 32.0 0.0 3.7e-06 26.9 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EJS43576.1 - 9.6e-07 28.4 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EJS43576.1 - 2.5e-06 27.1 0.1 2.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.11 EJS43576.1 - 2.9e-05 23.6 0.0 3.1e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.5 EJS43576.1 - 6.8e-05 22.4 0.1 7.4e-05 22.3 0.1 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 EJS43576.1 - 0.0017 18.3 0.1 0.0039 17.1 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EJS43576.1 - 0.0025 17.5 0.1 0.0032 17.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 EJS43576.1 - 0.026 14.0 0.1 0.037 13.5 0.0 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_6 PF13848.1 EJS43576.1 - 0.047 13.4 0.1 0.061 13.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain MMR_HSR1_C PF08438.5 EJS43577.1 - 9.7e-31 106.2 0.0 1.5e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EJS43577.1 - 3e-18 65.8 0.0 6.3e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EJS43577.1 - 1.6e-06 27.4 0.2 1.7e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EJS43577.1 - 0.0037 16.7 0.1 3.3 7.1 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EJS43577.1 - 0.013 15.2 0.2 0.078 12.8 0.0 2.3 3 0 0 3 3 3 0 Dynamin family AAA_10 PF12846.2 EJS43577.1 - 0.023 14.1 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EJS43577.1 - 0.066 14.0 0.6 0.67 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 EJS43577.1 - 0.077 12.5 0.4 9.4 5.6 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EJS43577.1 - 0.086 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArgK PF03308.11 EJS43577.1 - 0.095 11.4 0.8 0.24 10.1 0.0 2.0 3 0 0 3 3 3 0 ArgK protein KTI12 PF08433.5 EJS43577.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 zf-ZPR1 PF03367.8 EJS43578.1 - 1.1e-123 408.3 6.5 9.1e-62 206.9 1.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EJS43578.1 - 0.0018 17.9 4.6 0.42 10.3 0.3 2.6 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EJS43578.1 - 6.3 7.1 12.4 16 5.9 0.4 3.6 3 1 1 4 4 4 0 Restriction alleviation protein Lar Gpi1 PF05024.10 EJS43579.1 - 1.2e-64 217.4 17.2 1.2e-64 217.4 11.9 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) DUF3043 PF11241.3 EJS43579.1 - 0.9 9.1 8.2 0.093 12.3 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) CRM1_C PF08767.6 EJS43580.1 - 5.4e-129 429.6 6.7 5.4e-129 429.6 4.7 3.1 5 0 0 5 5 5 1 CRM1 C terminal Xpo1 PF08389.7 EJS43580.1 - 2.9e-38 131.0 7.2 2.9e-38 131.0 5.0 4.2 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EJS43580.1 - 8e-15 54.5 0.5 5.7e-14 51.7 0.1 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Ribosomal_L3 PF00297.17 EJS43581.1 - 2.7e-49 167.9 1.9 7.1e-48 163.2 1.3 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 WD40 PF00400.27 EJS43583.1 - 0.0018 18.1 0.0 0.95 9.4 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Nbas_N PF15492.1 EJS43583.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.4 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal DIE2_ALG10 PF04922.7 EJS43584.1 - 7e-141 469.6 39.7 7e-141 469.6 27.5 1.5 2 0 0 2 2 2 1 DIE2/ALG10 family SMI1_KNR4 PF09346.5 EJS43585.1 - 2.6e-35 121.2 4.2 3e-35 121.0 0.0 2.7 2 1 1 3 3 3 1 SMI1 / KNR4 family (SUKH-1) SLT_L PF14718.1 EJS43585.1 - 0.045 13.5 0.4 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain Band_7 PF01145.20 EJS43586.1 - 3.3e-22 79.2 1.1 5e-22 78.6 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ank_2 PF12796.2 EJS43587.1 - 1e-48 163.5 0.0 1.3e-14 54.2 0.0 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EJS43587.1 - 2e-30 103.0 0.0 3.7e-05 23.2 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EJS43587.1 - 1.4e-27 95.5 4.2 4.5e-08 33.3 0.0 5.6 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EJS43587.1 - 7.3e-26 89.6 0.6 9.8e-05 22.4 0.1 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EJS43587.1 - 8.5e-24 81.2 0.1 0.00021 21.2 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat ApoO PF09769.4 EJS43588.1 - 1.4e-39 135.3 0.0 2e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein O GCN5L1 PF06320.8 EJS43588.1 - 0.076 12.8 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Zip PF02535.17 EJS43589.1 - 2.5 7.0 9.4 4.8 6.1 6.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PFK PF00365.15 EJS43591.1 - 5.1e-168 557.1 3.3 9.7e-125 415.1 1.1 2.3 2 0 0 2 2 2 2 Phosphofructokinase ANTH PF07651.11 EJS43592.1 - 1.4e-70 237.2 2.5 1.4e-70 237.2 1.7 1.6 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 EJS43592.1 - 1.2e-08 34.8 0.3 1.2e-08 34.8 0.2 2.2 3 0 0 3 3 3 1 ENTH domain MPC PF03650.8 EJS43593.1 - 3.6e-54 181.8 0.4 4e-54 181.6 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ATP-grasp_2 PF08442.5 EJS43594.1 - 4.3e-79 264.5 0.3 6.8e-79 263.9 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EJS43594.1 - 2.3e-27 95.4 0.3 6.3e-27 94.0 0.1 1.9 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EJS43594.1 - 3.4e-08 32.9 0.1 5.5e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EJS43594.1 - 0.00081 19.0 0.1 0.0047 16.5 0.0 2.0 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Abhydrolase_1 PF00561.15 EJS43594.1 - 0.031 13.8 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold SDA1 PF05285.7 EJS43595.1 - 1.2e-94 317.2 35.8 1.2e-94 317.2 24.8 2.0 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 EJS43595.1 - 3.7e-23 81.5 1.5 2.2e-22 79.0 0.3 2.6 2 0 0 2 2 2 1 NUC130/3NT domain CPDase PF07823.6 EJS43596.1 - 4.2e-75 251.5 0.1 4.8e-75 251.3 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EJS43596.1 - 0.00092 18.9 0.1 0.0031 17.2 0.1 1.8 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Glucosamine_iso PF01182.15 EJS43597.1 - 2.2e-49 167.9 0.0 2.6e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RRM_1 PF00076.17 EJS43598.1 - 2.4e-32 110.3 0.2 1.9e-12 46.5 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS43598.1 - 4.8e-19 68.1 0.0 2.1e-06 27.5 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS43598.1 - 1.5e-13 50.3 0.6 0.00068 19.4 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2702 PF10863.3 EJS43599.1 - 3.1e-56 189.0 8.2 4.6e-56 188.5 5.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2702) Chlamy_scaf PF09675.5 EJS43599.1 - 0.049 13.6 0.3 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Bromodomain PF00439.20 EJS43600.1 - 3.5e-28 97.3 2.5 7.9e-28 96.2 1.7 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EJS43600.1 - 4.4e-09 36.3 0.2 9.2e-09 35.3 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EJS43600.1 - 1.4e-08 34.6 0.0 2.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EJS43600.1 - 0.0011 19.1 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EJS43600.1 - 0.0015 18.5 0.1 0.0031 17.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Proteasome PF00227.21 EJS43601.1 - 8.4e-54 181.7 0.0 1.1e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EJS43601.1 - 1.3e-13 49.9 0.1 3.9e-13 48.4 0.1 1.9 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Enolase_C PF00113.17 EJS43602.1 - 2e-151 503.0 0.0 3.1e-151 502.3 0.0 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EJS43602.1 - 5.6e-55 184.8 0.4 9.6e-55 184.1 0.3 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EJS43602.1 - 0.0022 17.9 0.1 0.0067 16.3 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EJS43602.1 - 0.011 14.7 0.5 0.057 12.3 0.0 2.0 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EJS43602.1 - 0.021 15.3 0.0 0.077 13.5 0.0 2.0 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain FAD_binding_3 PF01494.14 EJS43603.1 - 2.3e-18 66.4 0.5 1.9e-12 46.9 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 EJS43603.1 - 0.00022 20.1 0.0 0.00038 19.3 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 EJS43603.1 - 0.00087 18.3 0.0 0.016 14.1 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 EJS43603.1 - 0.0011 17.9 0.0 0.1 11.5 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EJS43603.1 - 0.0054 16.6 0.0 0.0097 15.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EJS43603.1 - 0.03 13.1 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EJS43603.1 - 0.036 14.1 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EJS43603.1 - 0.054 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EJS43603.1 - 0.062 11.9 0.0 0.53 8.8 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EJS43603.1 - 0.064 13.0 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EJS43603.1 - 0.093 11.1 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EJS43603.1 - 0.14 12.6 0.0 2.6 8.5 0.0 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase 6PGD PF00393.14 EJS43604.1 - 2e-130 434.2 0.0 2.5e-130 433.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EJS43604.1 - 9.9e-52 175.0 0.0 1.4e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EJS43604.1 - 0.082 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EJS43604.1 - 0.1 13.0 0.2 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EJS43604.1 - 0.12 11.5 0.1 0.27 10.3 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EJS43604.1 - 0.12 11.9 0.1 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XPG_N PF00752.12 EJS43605.1 - 1.9e-36 124.3 0.2 4.9e-36 123.0 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EJS43605.1 - 2.9e-26 91.3 0.0 1e-25 89.6 0.0 2.0 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EJS43605.1 - 0.00062 19.9 0.0 0.0022 18.1 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 EJS43605.1 - 0.0027 17.2 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing MFS_1 PF07690.11 EJS43606.1 - 3.4e-33 114.8 25.3 3.9e-33 114.6 16.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Kdo PF06293.9 EJS43607.1 - 1.3e-08 34.1 0.0 1.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EJS43607.1 - 7e-05 22.1 0.0 8.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EJS43607.1 - 0.00049 19.8 0.2 0.083 12.6 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EJS43607.1 - 0.039 13.0 0.0 0.051 12.6 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase DUF2424 PF10340.4 EJS43608.1 - 1.2e-156 521.0 2.0 1.4e-156 520.8 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EJS43608.1 - 3.4e-14 52.9 0.0 4.8e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EJS43608.1 - 0.039 13.7 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family tRNA-synt_1g PF09334.6 EJS43609.1 - 2.4e-147 490.7 0.2 3.1e-147 490.3 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 EJS43609.1 - 6.8e-50 168.5 3.5 1.9e-49 167.0 2.4 1.8 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1 PF00133.17 EJS43609.1 - 5.5e-09 34.5 0.7 0.0024 15.9 0.4 2.6 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) GTP_cyclohydroI PF01227.17 EJS43610.1 - 6.6e-75 250.3 0.1 8e-75 250.0 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EJS43610.1 - 1.1e-05 25.2 0.0 3.2e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 QueF-like protein OmpH PF03938.9 EJS43610.1 - 0.027 14.4 0.0 3.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DnaJ_CXXCXGXG PF00684.14 EJS43611.1 - 4.2e-06 26.7 4.6 0.031 14.3 0.2 2.4 2 0 0 2 2 2 2 DnaJ central domain HypA PF01155.14 EJS43611.1 - 0.051 13.2 2.4 0.27 10.9 0.3 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2318 PF10080.4 EJS43611.1 - 0.14 11.9 1.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) zf-RING_5 PF14634.1 EJS43611.1 - 2.1 8.1 7.3 9.3 6.0 0.1 2.8 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_3 PF14369.1 EJS43611.1 - 3.2 7.8 6.3 7.5 6.6 1.8 3.1 2 2 1 3 3 3 0 zinc-finger DUF605 PF04652.11 EJS43611.1 - 6.4 6.0 9.2 7.2 5.8 6.4 1.2 1 0 0 1 1 1 0 Vta1 like DUF2406 PF10295.4 EJS43612.1 - 5.9e-25 87.5 0.3 1.3e-24 86.4 0.2 1.6 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) UN_NPL4 PF11543.3 EJS43612.1 - 0.098 12.9 0.1 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Rtt102p PF09510.5 EJS43613.1 - 1.8e-38 131.4 0.7 2.6e-38 130.9 0.5 1.2 1 0 0 1 1 1 1 Rtt102p-like transcription regulator protein MA3 PF02847.12 EJS43614.1 - 2.2e-21 75.6 0.3 2.2e-21 75.6 0.2 2.6 3 0 0 3 3 3 1 MA3 domain MIF4G PF02854.14 EJS43614.1 - 9.5e-19 67.6 9.1 9.5e-19 67.6 6.3 3.0 3 0 0 3 3 3 2 MIF4G domain Glyco_hydro_17 PF00332.13 EJS43615.1 - 6.7e-10 38.5 0.5 6.7e-10 38.5 0.4 2.2 2 1 0 3 3 3 1 Glycosyl hydrolases family 17 Macoilin PF09726.4 EJS43615.1 - 4 5.6 6.8 5.1 5.2 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 EJS43615.1 - 4.2 5.3 7.9 5.1 5.0 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_pp85 PF04637.7 EJS43615.1 - 7.4 4.7 7.5 10 4.2 5.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) G-patch PF01585.18 EJS43616.1 - 1.7e-10 40.5 0.0 3.7e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EJS43616.1 - 0.00034 20.4 0.1 0.00034 20.4 0.0 3.5 2 1 1 3 3 2 1 DExH-box splicing factor binding site MIP-T3 PF10243.4 EJS43616.1 - 0.15 10.4 35.1 0.22 9.9 24.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RR_TM4-6 PF06459.7 EJS43616.1 - 0.17 11.7 16.7 0.25 11.1 11.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TAF1D PF15333.1 EJS43616.1 - 0.2 11.4 24.1 0.32 10.7 16.7 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Vfa1 PF08432.5 EJS43616.1 - 0.33 10.9 27.0 0.78 9.7 18.7 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2201_N PF13203.1 EJS43616.1 - 0.5 9.4 12.9 0.65 9.1 9.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain PP_M1 PF03012.9 EJS43616.1 - 0.51 9.6 15.3 0.73 9.1 10.6 1.2 1 0 0 1 1 1 0 Phosphoprotein CDC45 PF02724.9 EJS43616.1 - 1.9 6.4 21.8 2.6 5.9 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2422 PF10337.4 EJS43616.1 - 2.1 7.0 9.5 2.9 6.5 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Zip PF02535.17 EJS43616.1 - 3.3 6.6 13.7 4.2 6.2 9.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 EJS43616.1 - 4 4.9 19.3 5 4.6 13.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cellulose_synt PF03552.9 EJS43616.1 - 4.6 5.4 6.8 5.4 5.1 4.7 1.1 1 0 0 1 1 1 0 Cellulose synthase SOBP PF15279.1 EJS43616.1 - 8 6.7 13.2 11 6.3 9.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Glyco_hydro_17 PF00332.13 EJS43617.1 - 3.6e-79 266.0 3.2 4.2e-79 265.8 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF1088 PF06469.6 EJS43617.1 - 0.087 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) Methyltrn_RNA_3 PF02598.12 EJS43618.1 - 1.2e-73 248.0 0.1 1.4e-73 247.7 0.1 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase DUF705 PF05152.7 EJS43618.1 - 0.013 14.5 0.7 0.26 10.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF705) SURF4 PF02077.10 EJS43619.1 - 3.7e-109 364.2 12.0 4.3e-109 364.0 8.3 1.0 1 0 0 1 1 1 1 SURF4 family DnaJ PF00226.26 EJS43620.1 - 8.4e-17 60.6 0.2 8.4e-17 60.6 0.1 2.6 2 0 0 2 2 2 1 DnaJ domain BATS PF06968.8 EJS43621.1 - 6.9e-29 99.5 0.0 1.8e-28 98.1 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EJS43621.1 - 1.7e-16 60.8 0.6 3.8e-16 59.7 0.2 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Cyclin_N PF00134.18 EJS43622.1 - 6.4e-40 135.6 0.3 2.8e-39 133.5 0.2 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EJS43622.1 - 5.5e-28 97.2 0.0 1.2e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Acetyltransf_7 PF13508.1 EJS43623.1 - 2.7e-05 24.2 0.1 8.9e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TLD PF07534.11 EJS43623.1 - 0.029 14.3 0.3 0.098 12.6 0.1 2.0 2 0 0 2 2 2 0 TLD SURF1 PF02104.10 EJS43624.1 - 2.1e-66 223.8 0.0 2.8e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 SURF1 family SH2_2 PF14633.1 EJS43625.1 - 3.5e-110 366.3 2.9 1.5e-109 364.2 2.0 2.2 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.1 EJS43625.1 - 3e-69 231.3 0.0 9.6e-69 229.7 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 EJS43625.1 - 3.2e-51 172.2 4.5 3.2e-51 172.2 3.1 4.0 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 EJS43625.1 - 7.1e-48 161.0 0.2 2.4e-47 159.3 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 EJS43625.1 - 1.4e-44 150.9 2.8 1.4e-44 150.9 1.9 3.4 3 0 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EJS43625.1 - 1.4e-22 79.6 19.4 1.4e-22 79.6 13.4 5.2 5 1 0 5 5 5 1 Acidic N-terminal SPT6 SH2 PF00017.19 EJS43625.1 - 5.4e-14 51.7 0.2 2.5e-13 49.6 0.1 2.3 2 0 0 2 2 2 1 SH2 domain B2-adapt-app_C PF09066.5 EJS43625.1 - 0.0026 17.6 0.2 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain Nup54 PF13874.1 EJS43626.1 - 1.9e-41 141.0 5.1 1.9e-41 141.0 3.6 2.6 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EJS43626.1 - 2.2e-23 82.6 121.2 1.5e-10 41.2 31.6 4.0 1 1 1 2 2 2 2 Nucleoporin FG repeat region COG2 PF06148.6 EJS43627.1 - 6.5e-11 42.2 6.8 1.8e-10 40.8 4.7 1.8 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin_2 PF14523.1 EJS43627.1 - 0.0006 19.8 2.5 0.67 10.0 0.0 2.8 2 1 0 2 2 2 2 Syntaxin-like protein Pox_A6 PF04924.7 EJS43627.1 - 0.0011 17.9 0.4 0.0021 16.9 0.3 1.5 1 0 0 1 1 1 1 Poxvirus A6 protein AAA_31 PF13614.1 EJS43627.1 - 0.026 14.4 2.6 0.15 11.9 0.1 2.4 1 1 1 2 2 2 0 AAA domain LOH1CR12 PF10158.4 EJS43627.1 - 0.068 12.9 2.5 0.17 11.6 0.7 2.2 1 1 2 3 3 3 0 Tumour suppressor protein NusB PF01029.13 EJS43627.1 - 0.11 12.4 1.1 0.21 11.5 0.5 1.7 1 1 0 1 1 1 0 NusB family G6PD_bact PF10786.4 EJS43627.1 - 0.14 11.6 1.5 0.19 11.1 0.8 1.5 1 1 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) NPV_P10 PF05531.7 EJS43627.1 - 0.19 11.9 1.6 10 6.4 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1910 PF08928.5 EJS43627.1 - 0.21 11.5 2.3 1.4 9.0 1.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) Metallophos PF00149.23 EJS43629.1 - 1.6e-37 128.9 0.2 2.3e-37 128.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EJS43629.1 - 2.1e-20 72.1 2.4 2.5e-17 62.2 0.0 2.7 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EJS43629.1 - 2.7e-15 54.9 3.3 5e-05 22.9 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EJS43629.1 - 1.5e-12 46.5 5.5 4.9e-06 25.9 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat PPP5 PF08321.7 EJS43629.1 - 1.6e-12 47.2 0.1 1.9e-09 37.3 0.0 3.1 2 1 0 2 2 2 1 PPP5 TPR repeat region TPR_17 PF13431.1 EJS43629.1 - 1.2e-05 25.1 2.1 0.22 11.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EJS43629.1 - 0.0001 22.5 3.9 0.00035 20.8 0.4 2.5 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EJS43629.1 - 0.00013 21.6 0.0 0.00073 19.3 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EJS43629.1 - 0.00028 20.6 0.1 0.19 11.5 0.0 2.7 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 EJS43629.1 - 0.00035 21.1 0.0 0.03 14.9 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EJS43629.1 - 0.00072 19.9 0.1 0.9 10.3 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat NBP1 PF08537.5 EJS43629.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 TPR_12 PF13424.1 EJS43629.1 - 0.038 13.9 0.1 0.47 10.4 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Asn_synthase PF00733.16 EJS43630.1 - 7.7e-71 238.5 0.0 1.1e-70 238.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EJS43630.1 - 4.1e-34 117.0 0.0 6.9e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EJS43630.1 - 1.3e-27 96.3 0.0 9.4e-27 93.5 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EJS43630.1 - 3e-08 33.1 0.0 5.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EJS43630.1 - 7.3e-06 24.9 0.0 0.27 9.8 0.0 3.0 1 1 2 3 3 3 3 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EJS43630.1 - 0.002 17.0 0.0 0.0036 16.2 0.0 1.4 1 0 0 1 1 1 1 NAD synthase Sulfate_transp PF00916.15 EJS43631.1 - 5.4e-59 199.5 10.4 5.4e-59 199.5 7.2 1.9 2 0 0 2 2 2 1 Sulfate transporter family STAS PF01740.16 EJS43631.1 - 6.7e-17 60.9 1.2 1.4e-16 59.9 0.8 1.6 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 EJS43631.1 - 7.6e-06 25.6 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF3484 PF11983.3 EJS43632.1 - 0.2 12.4 1.8 1 10.2 1.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) Utp8 PF10395.4 EJS43633.1 - 7.3e-228 758.1 28.7 8.3e-228 758.0 19.9 1.0 1 0 0 1 1 1 1 Utp8 family Rtt106 PF08512.7 EJS43633.1 - 0.15 12.0 2.6 0.3 11.0 0.3 2.6 2 1 1 3 3 3 0 Histone chaperone Rttp106-like SYF2 PF08231.7 EJS43634.1 - 2.8e-11 43.7 16.7 5.9e-11 42.7 11.6 1.4 1 0 0 1 1 1 1 SYF2 splicing factor Poxvirus PF06227.7 EJS43634.1 - 0.021 14.4 4.1 0.035 13.6 2.9 1.4 1 0 0 1 1 1 0 dsDNA Poxvirus Chordopox_G3 PF06129.7 EJS43634.1 - 0.35 11.0 4.3 0.2 11.8 0.9 2.1 2 1 1 3 3 3 0 Chordopoxvirus G3 protein MARVEL PF01284.18 EJS43636.1 - 1.1e-28 99.8 11.5 1.3e-28 99.6 8.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF1218 PF06749.7 EJS43636.1 - 0.0022 18.4 2.2 0.0027 18.1 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1218) Tetraspannin PF00335.15 EJS43636.1 - 0.0071 15.6 1.7 0.0071 15.6 1.2 2.0 1 1 1 2 2 2 1 Tetraspanin family DUF3844 PF12955.2 EJS43636.1 - 0.03 14.3 0.9 0.05 13.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) zinc_ribbon_4 PF13717.1 EJS43636.1 - 0.12 12.0 0.4 0.19 11.4 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EJS43636.1 - 0.12 11.9 0.4 0.2 11.2 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain MerC PF03203.9 EJS43636.1 - 0.68 10.3 4.5 1.4 9.3 0.2 2.6 2 1 1 3 3 3 0 MerC mercury resistance protein Band_7 PF01145.20 EJS43637.1 - 1.9e-26 93.0 2.2 3e-26 92.3 1.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EJS43637.1 - 0.011 15.2 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Proteasome PF00227.21 EJS43639.1 - 8e-58 194.8 0.6 9.8e-58 194.5 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EJS43639.1 - 2.1e-13 49.2 0.2 4.2e-13 48.3 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lipocalin_6 PF13944.1 EJS43639.1 - 0.014 15.4 0.9 5.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Lipocalin-like domain SH3_1 PF00018.23 EJS43640.1 - 3.7e-17 61.4 0.0 7.5e-17 60.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EJS43640.1 - 5.3e-14 51.5 0.0 9e-14 50.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EJS43640.1 - 1.9e-11 43.2 0.0 2.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF605 PF04652.11 EJS43640.1 - 0.03 13.7 18.5 0.034 13.5 12.8 1.1 1 0 0 1 1 1 0 Vta1 like E_Pc_C PF06752.7 EJS43640.1 - 0.069 12.6 6.4 0.1 12.0 4.4 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus PAT1 PF09770.4 EJS43640.1 - 0.18 10.0 17.6 0.2 9.8 12.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EJS43640.1 - 4.4 7.1 9.2 5.6 6.7 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.11 EJS43641.1 - 1.1e-31 109.8 32.1 1.1e-31 109.8 22.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Nucleo_P87 PF07267.6 EJS43641.1 - 2.3 6.7 5.1 3.2 6.3 3.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 V_ATPase_I PF01496.14 EJS43642.1 - 5.9 4.6 11.4 7.7 4.2 7.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 EJS43643.1 - 3.3e-71 239.4 0.0 4.1e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43643.1 - 1.1e-32 113.1 0.1 1.6e-32 112.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43643.1 - 1.2e-06 27.7 0.0 2.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EJS43643.1 - 0.0027 16.8 0.0 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS43643.1 - 0.011 15.5 0.1 0.044 13.5 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF2439 PF10382.4 EJS43645.1 - 3.3e-25 88.1 1.2 8e-25 86.8 0.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Mmp37 PF09139.6 EJS43646.1 - 9.7e-104 346.9 11.6 4.6e-94 315.1 2.6 2.1 1 1 1 2 2 2 2 Mitochondrial matrix Mmp37 UFD1 PF03152.9 EJS43647.1 - 2.8e-73 244.8 0.0 4.7e-73 244.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Pkinase PF00069.20 EJS43649.1 - 2.2e-50 171.2 0.1 2.6e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43649.1 - 1.3e-25 89.9 0.0 1.9e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43649.1 - 4.2e-05 22.6 0.0 0.00011 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EJS43649.1 - 0.0018 18.0 0.0 0.85 9.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family eIF2A PF08662.6 EJS43650.1 - 1.6e-75 253.0 0.1 7.4e-75 250.9 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EJS43650.1 - 0.0018 18.0 0.6 8.4 6.4 0.1 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat EF-hand_7 PF13499.1 EJS43651.1 - 2.7e-09 37.0 2.4 0.0016 18.5 0.2 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EJS43651.1 - 2.1e-08 33.3 1.4 0.019 14.7 0.0 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EJS43651.1 - 4.2e-06 25.6 0.0 3.3 7.2 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EJS43651.1 - 2e-05 24.0 0.1 5.6 6.6 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EJS43651.1 - 0.027 13.8 0.4 9.1 5.8 0.0 3.7 5 0 0 5 5 5 0 EF hand Septin PF00735.13 EJS43652.1 - 8.2e-101 336.7 1.2 8.2e-101 336.7 0.8 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EJS43652.1 - 2.1e-05 24.4 0.0 6.4e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EJS43652.1 - 0.00081 18.5 1.2 0.003 16.6 0.0 2.4 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 EJS43652.1 - 0.0023 17.1 0.2 0.0023 17.1 0.2 3.4 3 1 0 3 3 3 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EJS43652.1 - 0.0043 16.2 0.6 0.032 13.3 0.0 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region CCDC92 PF14916.1 EJS43652.1 - 0.0088 15.6 1.4 0.032 13.8 1.0 1.9 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Miro PF08477.8 EJS43652.1 - 0.013 15.9 0.0 0.059 13.8 0.0 2.2 1 0 0 1 1 1 0 Miro-like protein AAA_24 PF13479.1 EJS43652.1 - 0.032 13.8 0.0 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EJS43652.1 - 0.033 13.1 0.1 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EJS43652.1 - 0.043 13.3 0.7 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family S6PP PF05116.8 EJS43652.1 - 0.066 12.5 0.9 0.12 11.6 0.6 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase AAA_33 PF13671.1 EJS43652.1 - 0.083 12.7 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsL PF04999.8 EJS43652.1 - 0.99 9.1 3.8 0.35 10.5 0.4 1.8 2 0 0 2 2 2 0 Cell division protein FtsL FA_hydroxylase PF04116.8 EJS43653.1 - 4.4e-16 59.2 18.6 4.4e-16 59.2 12.9 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FDC-SP PF15215.1 EJS43653.1 - 0.019 15.2 1.3 0.052 13.8 0.9 1.7 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide GATase_5 PF13507.1 EJS43654.1 - 2.3e-97 324.9 0.0 3.4e-97 324.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EJS43654.1 - 4.4e-49 166.3 0.5 7.1e-28 97.5 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EJS43654.1 - 1.8e-21 76.1 0.1 7.2e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Peptidase_C93 PF06035.6 EJS43654.1 - 0.093 12.1 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP 60KD_IMP PF02096.15 EJS43655.1 - 2.7e-14 53.2 18.0 4.4e-13 49.3 12.5 2.1 1 1 0 1 1 1 1 60Kd inner membrane protein F-box-like_2 PF13013.1 EJS43655.1 - 0.018 14.7 0.2 0.034 13.8 0.1 1.5 1 1 0 1 1 1 0 F-box-like domain Spt4 PF06093.8 EJS43656.1 - 6.2e-29 99.7 0.6 7.2e-29 99.4 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Vac_ImportDeg PF09783.4 EJS43657.1 - 5.7e-57 192.0 0.4 7.2e-57 191.7 0.3 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Arrestin_C PF02752.17 EJS43658.1 - 4.1e-18 65.7 0.3 1.8e-17 63.7 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EJS43658.1 - 3e-08 33.6 0.1 4.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain CNH PF00780.17 EJS43659.1 - 7.1e-55 186.3 0.3 1.3e-54 185.5 0.2 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EJS43659.1 - 5.8e-36 123.4 0.2 5.8e-36 123.4 0.2 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 EJS43659.1 - 1.1e-30 106.9 0.2 3.7e-30 105.1 0.1 2.0 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EJS43659.1 - 1.1e-08 34.7 0.0 2.9e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1327 PF07041.6 EJS43659.1 - 0.029 14.2 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) Smg4_UPF3 PF03467.10 EJS43660.1 - 4.1e-54 183.2 7.4 4.1e-54 183.2 5.1 2.0 3 0 0 3 3 3 1 Smg-4/UPF3 family DUF572 PF04502.8 EJS43660.1 - 3.9 6.6 41.0 0.17 11.0 17.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) LSM PF01423.17 EJS43661.1 - 8.9e-22 76.4 0.2 1.4e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EJS43661.1 - 0.0016 18.3 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LRR_1 PF00560.28 EJS43661.1 - 0.2 11.8 1.5 2.1 8.6 1.0 2.6 1 1 0 1 1 1 0 Leucine Rich Repeat Prefoldin PF02996.12 EJS43664.1 - 3.8e-37 126.5 0.1 5.5e-37 126.0 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EJS43664.1 - 0.0031 17.2 2.2 0.36 10.5 0.0 2.4 2 0 0 2 2 2 2 Prefoldin subunit MAD PF05557.8 EJS43664.1 - 0.0053 14.9 1.4 0.025 12.6 0.1 1.9 2 0 0 2 2 2 1 Mitotic checkpoint protein zf-C4H2 PF10146.4 EJS43664.1 - 0.024 14.6 0.3 0.055 13.4 0.1 1.5 1 1 0 2 2 2 0 Zinc finger-containing protein DUF4476 PF14771.1 EJS43664.1 - 0.03 14.3 0.1 0.072 13.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) CENP-Q PF13094.1 EJS43664.1 - 0.032 14.2 1.4 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.4 EJS43664.1 - 0.19 11.5 4.6 5.7 6.7 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.7 EJS43664.1 - 0.22 11.4 3.3 1.5 8.7 0.0 3.6 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat ADIP PF11559.3 EJS43664.1 - 0.64 9.9 4.3 3.4 7.5 0.6 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cofilin_ADF PF00241.15 EJS43665.1 - 7.8e-38 129.2 0.1 1.4e-17 63.7 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein SLX9 PF15341.1 EJS43666.1 - 5.8e-21 75.1 7.7 1e-20 74.3 5.4 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 MAS20 PF02064.10 EJS43667.1 - 6.2e-21 74.5 0.3 1.1e-19 70.5 0.2 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor PsbN PF02468.10 EJS43667.1 - 0.14 11.8 0.5 0.29 10.7 0.3 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) IF-2B PF01008.12 EJS43668.1 - 9.5e-110 366.0 0.1 9.5e-110 366.0 0.0 2.0 2 0 0 2 2 2 1 Initiation factor 2 subunit family DUF4263 PF14082.1 EJS43668.1 - 0.24 11.3 7.7 0.65 9.9 5.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) LMBR1 PF04791.11 EJS43668.1 - 0.26 9.8 5.3 0.47 8.9 3.6 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_11 PF13086.1 EJS43668.1 - 4.2 6.8 19.5 0.82 9.2 8.0 3.0 3 0 0 3 3 3 0 AAA domain Ribosomal_L5_C PF00673.16 EJS43669.1 - 5.8e-23 80.4 0.0 8.7e-23 79.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EJS43669.1 - 1.3e-20 72.9 0.1 3.4e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Pil1 PF13805.1 EJS43670.1 - 3.5e-155 515.0 0.2 4.1e-155 514.7 0.1 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 TPP_enzyme_M PF00205.17 EJS43671.1 - 2.3e-32 111.6 0.0 1e-31 109.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 EJS43671.1 - 3.4e-32 111.3 0.0 5.3e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EJS43671.1 - 7e-13 48.4 0.0 1.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DivIC PF04977.10 EJS43672.1 - 0.0077 15.6 4.9 0.0077 15.6 3.4 4.9 5 0 0 5 5 5 1 Septum formation initiator Laminin_II PF06009.7 EJS43672.1 - 0.027 14.2 22.9 1.4 8.6 7.2 2.9 1 1 1 2 2 2 0 Laminin Domain II Cast PF10174.4 EJS43672.1 - 0.14 10.2 32.6 0.23 9.4 22.6 1.3 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF1664 PF07889.7 EJS43672.1 - 0.32 10.7 18.1 0.38 10.5 5.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF641 PF04859.7 EJS43672.1 - 0.53 10.0 21.2 3.3 7.4 5.6 3.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF2353 PF09789.4 EJS43672.1 - 0.67 9.1 31.6 0.026 13.7 9.7 2.4 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Dna2 PF08696.6 EJS43672.1 - 3.1 7.0 9.5 0.11 11.7 1.2 2.3 2 0 0 2 2 2 0 DNA replication factor Dna2 IncA PF04156.9 EJS43672.1 - 8.2 5.9 34.8 11 5.4 10.1 2.6 1 1 1 2 2 2 0 IncA protein RasGAP_C PF03836.10 EJS43672.1 - 8.8 6.0 35.7 0.1 12.3 7.8 3.4 2 1 2 4 4 4 0 RasGAP C-terminus Bap31 PF05529.7 EJS43672.1 - 9.8 5.5 23.9 3.9 6.8 5.6 3.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Nrap PF03813.9 EJS43673.1 - 0 1227.5 2.5 0 1227.3 1.8 1.1 1 0 0 1 1 1 1 Nrap protein Pkinase PF00069.20 EJS43674.1 - 6.4e-55 186.1 0.1 7.1e-54 182.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43674.1 - 1.4e-28 99.7 0.2 3.9e-20 72.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EJS43674.1 - 7.8e-06 26.3 3.6 9.7e-05 22.8 0.8 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EJS43674.1 - 0.0013 17.7 0.0 0.015 14.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EJS43674.1 - 0.019 14.0 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS43674.1 - 0.074 12.7 0.0 0.43 10.2 0.0 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family CwfJ_C_1 PF04677.10 EJS43675.1 - 1.3e-40 137.8 0.4 3.2e-40 136.5 0.3 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EJS43675.1 - 4.5e-22 78.3 0.5 1.2e-21 77.0 0.4 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.18 EJS43675.1 - 0.036 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 HIT domain Osmo_CC PF08946.5 EJS43675.1 - 0.1 12.6 0.5 0.33 11.0 0.3 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil tRNA-synt_1 PF00133.17 EJS43676.1 - 2e-234 779.1 0.1 1.1e-233 776.6 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EJS43676.1 - 2.1e-32 112.0 2.7 6.4e-32 110.4 1.9 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EJS43676.1 - 2.1e-18 66.1 0.3 4.1e-10 38.8 0.1 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EJS43676.1 - 8.9e-08 31.6 12.9 8.4e-07 28.4 0.0 3.9 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 EJS43676.1 - 4.5e-05 23.4 6.8 4.5e-05 23.4 4.7 2.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm RNase_PH PF01138.16 EJS43677.1 - 5.3e-17 62.3 0.0 1e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EJS43677.1 - 1.4e-08 34.5 0.4 3.7e-08 33.1 0.1 1.8 1 1 1 2 2 2 1 3' exoribonuclease family, domain 2 Mito_carr PF00153.22 EJS43678.1 - 5e-63 208.8 4.2 3e-22 78.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Herpes_IE1 PF07340.6 EJS43678.1 - 0.14 10.5 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein PH PF00169.24 EJS43679.1 - 2.4e-35 120.8 0.6 7.8e-35 119.2 0.4 2.0 1 0 0 1 1 1 1 PH domain Peptidase_C50 PF03568.12 EJS43680.1 - 2.9e-137 457.4 0.6 7e-137 456.1 0.4 1.7 1 0 0 1 1 1 1 Peptidase family C50 Telomere_reg-2 PF10193.4 EJS43681.1 - 4.3e-27 94.6 0.3 1.3e-26 93.0 0.2 1.9 1 0 0 1 1 1 1 Telomere length regulation protein RabGAP-TBC PF00566.13 EJS43682.1 - 5.4e-52 176.3 0.8 1.4e-51 175.0 0.6 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 EJS43682.1 - 2.6e-15 55.7 0.0 6.6e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.1 EJS43682.1 - 4.3e-06 26.7 1.5 3.3e-05 23.9 0.9 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EJS43682.1 - 1.5e-05 24.4 0.9 0.0021 17.7 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EJS43682.1 - 0.027 13.7 0.1 0.13 11.6 0.0 2.3 2 0 0 2 2 2 0 EF hand Rhomboid PF01694.17 EJS43683.1 - 9.5e-30 103.5 15.6 9.5e-30 103.5 10.8 1.7 2 0 0 2 2 2 1 Rhomboid family Imm14 PF15428.1 EJS43683.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 14 Pescadillo_N PF06732.6 EJS43685.1 - 3.2e-127 423.5 1.8 3.2e-127 423.5 1.2 3.0 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EJS43685.1 - 5.1e-12 45.7 0.0 2.9e-11 43.3 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Med18 PF09637.5 EJS43686.1 - 6e-78 261.8 0.0 6.9e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Med18 protein VMA21 PF09446.5 EJS43687.1 - 1.1e-16 60.5 9.6 1.4e-16 60.1 6.6 1.2 1 0 0 1 1 1 1 VMA21-like domain MscS_TM PF12794.2 EJS43687.1 - 0.03 12.9 0.1 0.03 12.9 0.1 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DAD PF02109.11 EJS43687.1 - 0.043 13.8 0.2 0.046 13.7 0.1 1.0 1 0 0 1 1 1 0 DAD family DUF1469 PF07332.6 EJS43687.1 - 4.6 7.0 7.9 10 5.8 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) ATP-synt_S1 PF05827.7 EJS43688.1 - 0.00013 21.4 0.0 0.00017 21.0 0.0 1.3 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Thg1 PF04446.7 EJS43689.1 - 3.4e-45 152.9 0.2 4.5e-45 152.5 0.1 1.1 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 EJS43689.1 - 1e-37 128.5 0.3 1.8e-37 127.6 0.2 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain DUF3223 PF11523.3 EJS43689.1 - 0.026 14.8 0.1 0.54 10.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3223) Ribosomal_S25 PF03297.10 EJS43691.1 - 5e-45 151.8 4.5 5.6e-45 151.6 3.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 EJS43691.1 - 0.0001 21.9 0.1 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain EAP30 PF04157.11 EJS43691.1 - 0.025 13.7 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_CodY PF08222.6 EJS43691.1 - 0.047 13.0 0.2 0.075 12.3 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain Gp49 PF05973.9 EJS43691.1 - 0.11 12.4 1.1 3.6 7.6 0.4 2.2 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) MerR PF00376.18 EJS43691.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein AAA PF00004.24 EJS43692.1 - 1.4e-39 135.2 0.0 2.3e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EJS43692.1 - 1.7e-07 31.1 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EJS43692.1 - 3.4e-07 30.4 0.2 0.00023 21.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EJS43692.1 - 5.8e-07 30.3 0.0 1.4e-06 29.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EJS43692.1 - 1.5e-06 28.3 0.4 0.00063 19.8 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EJS43692.1 - 3.3e-06 26.8 0.2 5e-05 23.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EJS43692.1 - 3.3e-06 26.3 0.0 8.3e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EJS43692.1 - 3.9e-06 26.8 0.0 8.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EJS43692.1 - 3.3e-05 23.8 0.0 0.00026 20.8 0.0 2.4 3 1 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EJS43692.1 - 9.8e-05 21.5 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Sigma54_activ_2 PF14532.1 EJS43692.1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 EJS43692.1 - 0.00028 21.1 0.0 0.00069 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EJS43692.1 - 0.00039 19.8 0.0 0.00084 18.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EJS43692.1 - 0.00058 19.0 0.2 0.0016 17.6 0.1 1.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EJS43692.1 - 0.00059 19.9 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.8 EJS43692.1 - 0.00092 18.2 0.0 0.0018 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 EJS43692.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_25 PF13481.1 EJS43692.1 - 0.0014 18.0 0.7 0.023 14.1 0.1 2.4 1 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EJS43692.1 - 0.0021 17.7 0.1 0.0095 15.6 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 EJS43692.1 - 0.0032 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EJS43692.1 - 0.0035 16.8 0.2 1.5 8.1 0.0 2.5 1 1 1 2 2 2 1 AAA-like domain AAA_24 PF13479.1 EJS43692.1 - 0.004 16.7 0.1 0.008 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 EJS43692.1 - 0.0059 15.3 0.0 0.0085 14.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 EJS43692.1 - 0.0063 16.8 0.0 0.018 15.3 0.0 1.9 1 1 0 1 1 1 1 ABC transporter TIP49 PF06068.8 EJS43692.1 - 0.0082 14.9 0.1 0.018 13.7 0.0 1.6 1 1 0 1 1 1 1 TIP49 C-terminus Arch_ATPase PF01637.13 EJS43692.1 - 0.011 15.4 0.7 0.089 12.4 0.0 2.5 3 1 1 4 4 3 0 Archaeal ATPase Sigma54_activat PF00158.21 EJS43692.1 - 0.012 15.1 0.0 0.041 13.3 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 EJS43692.1 - 0.013 14.5 0.2 1.2 8.0 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain AAA_3 PF07726.6 EJS43692.1 - 0.019 14.5 0.0 0.048 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EJS43692.1 - 0.021 14.5 0.1 0.064 13.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain SKI PF01202.17 EJS43692.1 - 0.027 14.3 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase Viral_helicase1 PF01443.13 EJS43692.1 - 0.032 13.7 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 EJS43692.1 - 0.036 12.9 0.1 0.072 11.9 0.0 1.5 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EJS43692.1 - 0.057 12.2 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 EJS43692.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IPT PF01745.11 EJS43692.1 - 0.12 11.4 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase KaiC PF06745.8 EJS43692.1 - 0.15 11.1 0.4 1.1 8.3 0.0 2.3 2 1 1 3 3 3 0 KaiC Alba PF01918.16 EJS43693.1 - 2.3e-09 36.7 0.1 3.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Alba CDK2AP PF09806.4 EJS43693.1 - 0.043 14.0 0.1 0.048 13.8 0.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4145 PF13643.1 EJS43693.1 - 0.18 11.6 2.6 1 9.2 1.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) Glucan_synthase PF02364.10 EJS43694.1 - 0 1455.0 0.0 0 1454.5 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EJS43694.1 - 4.1e-40 136.3 0.0 1.2e-39 134.8 0.0 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TIM21 PF08294.6 EJS43695.1 - 8.7e-59 197.3 0.1 1.2e-58 196.8 0.1 1.2 1 0 0 1 1 1 1 TIM21 KASH PF10541.4 EJS43696.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear envelope localisation domain PAP2 PF01569.16 EJS43697.1 - 1.8e-19 69.6 0.4 1.8e-19 69.6 0.3 1.6 2 0 0 2 2 2 1 PAP2 superfamily ACBP PF00887.14 EJS43698.1 - 1.5e-30 104.7 0.8 1.6e-30 104.5 0.6 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF1413 PF07205.6 EJS43698.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) ORMDL PF04061.9 EJS43699.1 - 3.3e-58 195.0 4.5 4e-58 194.7 3.1 1.1 1 0 0 1 1 1 1 ORMDL family Pyridox_oxase_2 PF12766.2 EJS43701.1 - 1.7e-31 108.5 0.2 3.1e-31 107.6 0.1 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4163 PF13739.1 EJS43701.1 - 0.042 14.6 3.0 0.072 13.8 0.7 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4163) Aminotran_3 PF00202.16 EJS43702.1 - 3.2e-87 292.5 0.0 3.8e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ATP-synt_F PF01990.12 EJS43703.1 - 6.3e-32 109.8 0.3 7.3e-32 109.6 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 EJS43703.1 - 0.025 13.8 0.1 0.03 13.6 0.1 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Mid2 PF04478.7 EJS43704.1 - 1.4e-69 232.4 1.9 1.4e-69 232.4 1.3 4.7 2 1 3 6 6 6 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EJS43704.1 - 0.002 17.4 4.3 0.016 14.5 3.0 2.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain HSCB_C PF07743.8 EJS43705.1 - 2.9e-16 59.6 5.7 8.9e-15 54.9 0.8 2.1 2 0 0 2 2 2 2 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EJS43705.1 - 3.2e-15 55.6 0.3 6.5e-15 54.6 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2533 PF10752.4 EJS43705.1 - 0.048 13.9 0.3 0.12 12.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) M157 PF11624.3 EJS43705.1 - 0.054 12.6 0.2 0.059 12.4 0.1 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 WASH-7_C PF14746.1 EJS43705.1 - 0.78 9.3 5.4 0.17 11.4 0.4 2.0 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal DUF2630 PF10944.3 EJS43705.1 - 0.88 9.7 4.3 0.35 10.9 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) Cortex-I_coil PF09304.5 EJS43705.1 - 2.1 8.3 9.8 0.27 11.3 0.8 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil ATE_C PF04377.10 EJS43706.1 - 3.8e-43 146.5 1.1 6.4e-43 145.8 0.7 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EJS43706.1 - 2e-22 78.7 0.5 5e-22 77.4 0.3 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus PUF PF00806.14 EJS43708.1 - 7e-67 217.3 18.8 6.7e-10 37.9 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat ERG4_ERG24 PF01222.12 EJS43709.1 - 3.8e-190 631.9 31.7 4.3e-190 631.8 22.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CytoC_RC PF02276.13 EJS43709.1 - 0.035 13.2 0.1 0.051 12.6 0.1 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Proteasome PF00227.21 EJS43710.1 - 2.2e-47 160.8 0.0 3.2e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EJS43710.1 - 1.9e-15 55.8 0.1 3.4e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF962 PF06127.6 EJS43711.1 - 1.1e-27 95.7 6.6 3.8e-27 94.0 4.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF962) EMP70 PF02990.11 EJS43711.1 - 0.03 12.8 1.7 0.038 12.4 1.1 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 MarC PF01914.12 EJS43711.1 - 0.095 11.8 1.3 0.13 11.3 0.9 1.3 1 0 0 1 1 1 0 MarC family integral membrane protein Aconitase PF00330.15 EJS43712.1 - 1e-195 650.6 0.1 1.2e-195 650.3 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EJS43712.1 - 1.5e-47 160.9 0.0 3.1e-47 159.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain E1-E2_ATPase PF00122.15 EJS43713.1 - 6.9e-63 211.7 5.0 1.5e-62 210.6 3.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EJS43713.1 - 1.9e-23 84.0 0.0 3.7e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EJS43713.1 - 5.7e-14 52.7 0.0 2.1e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EJS43713.1 - 9e-12 44.2 0.0 2.5e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EJS43713.1 - 0.0013 18.4 0.1 0.0027 17.3 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EJS43713.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EJS43714.1 - 9.4e-61 204.7 1.0 9.4e-61 204.7 0.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EJS43714.1 - 2.3e-41 141.3 8.6 2.3e-41 141.3 6.0 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EJS43714.1 - 2.9e-26 93.2 0.0 1.5e-20 74.5 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EJS43714.1 - 5.1e-14 52.8 0.0 1.5e-13 51.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EJS43714.1 - 1e-13 51.0 0.1 3.3e-13 49.3 0.1 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EJS43714.1 - 1.4e-10 40.4 0.0 5e-10 38.6 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EJS43714.1 - 9.1e-05 22.1 6.2 0.00027 20.5 0.2 3.2 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase COG5 PF10392.4 EJS43715.1 - 0.0076 16.2 0.6 0.0076 16.2 0.4 3.1 1 1 2 3 3 3 2 Golgi transport complex subunit 5 FliS PF02561.9 EJS43715.1 - 0.025 14.4 0.3 0.025 14.4 0.2 2.6 2 1 0 2 2 2 0 Flagellar protein FliS DUF919 PF06034.6 EJS43715.1 - 0.17 11.5 4.1 0.14 11.7 1.2 2.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Laminin_II PF06009.7 EJS43715.1 - 0.19 11.5 7.6 0.13 12.0 3.2 2.3 1 1 1 2 2 2 0 Laminin Domain II Reo_sigmaC PF04582.7 EJS43715.1 - 1.1 8.3 8.3 0.36 9.9 2.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein WD40 PF00400.27 EJS43716.1 - 4.9e-30 102.2 5.4 2.6e-06 27.1 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EJS43716.1 - 4.6e-08 33.0 0.6 0.0011 18.7 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF4572 PF15139.1 EJS43716.1 - 0.12 12.2 1.0 0.22 11.3 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) EMP24_GP25L PF01105.19 EJS43717.1 - 1.8e-49 167.9 0.0 2.1e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2846 PF11008.3 EJS43717.1 - 0.025 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) Remorin_C PF03763.8 EJS43717.1 - 0.064 12.7 0.6 0.092 12.2 0.4 1.2 1 0 0 1 1 1 0 Remorin, C-terminal region FixQ PF05545.6 EJS43717.1 - 7.7 6.2 6.9 0.45 10.1 0.1 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ 3Beta_HSD PF01073.14 EJS43718.1 - 6.9e-96 320.2 0.0 8.4e-96 319.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EJS43718.1 - 1.9e-34 119.1 0.0 2.5e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EJS43718.1 - 9.9e-17 60.7 0.0 1.7e-16 59.9 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EJS43718.1 - 4.2e-16 58.6 0.0 1.3e-15 57.0 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EJS43718.1 - 7.2e-11 42.4 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EJS43718.1 - 1.1e-09 37.6 0.0 1.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EJS43718.1 - 6.6e-06 26.1 0.0 1.5e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EJS43718.1 - 0.00022 20.9 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EJS43718.1 - 0.0067 15.6 0.0 0.0095 15.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EJS43718.1 - 0.032 14.5 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Myb_DNA-bind_6 PF13921.1 EJS43719.1 - 0.003 17.6 0.5 0.003 17.6 0.3 3.0 3 1 1 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EJS43719.1 - 0.016 15.2 0.1 0.047 13.7 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3408 PF11888.3 EJS43719.1 - 2.5 8.0 9.7 0.34 10.8 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF342 PF03961.8 EJS43719.1 - 7 4.9 8.1 11 4.2 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pex24p PF06398.6 EJS43720.1 - 1.3e-81 274.1 12.5 1.7e-81 273.8 8.7 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3329 PF11808.3 EJS43720.1 - 0.062 13.3 5.5 0.083 12.9 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) TFIIF_beta PF02270.10 EJS43721.1 - 2.7e-96 322.5 16.5 4.9e-96 321.7 11.4 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Prp18 PF02840.10 EJS43722.1 - 5.1e-45 152.8 0.2 9.5e-45 151.9 0.1 1.4 1 0 0 1 1 1 1 Prp18 domain CTP_transf_2 PF01467.21 EJS43723.1 - 2.4e-26 92.6 0.2 2.6e-19 69.8 0.1 2.4 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EJS43723.1 - 0.05 13.2 2.8 7.5 6.1 0.2 3.0 3 1 0 3 3 3 0 FAD synthetase HABP4_PAI-RBP1 PF04774.10 EJS43724.1 - 2e-05 25.0 2.1 2.7e-05 24.6 1.4 1.3 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family CTP_transf_2 PF01467.21 EJS43726.1 - 3.3e-36 124.7 0.0 9.5e-36 123.2 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase PALP PF00291.20 EJS43727.1 - 7.9e-60 202.6 1.0 9.2e-60 202.4 0.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_60s PF00428.14 EJS43728.1 - 0.022 15.1 5.3 0.022 15.1 3.7 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein FOP_dimer PF09398.5 EJS43728.1 - 0.06 13.3 1.3 0.15 12.0 0.1 2.3 2 0 0 2 2 2 0 FOP N terminal dimerisation domain Epimerase PF01370.16 EJS43729.1 - 1.3e-14 54.2 0.0 2e-14 53.5 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EJS43729.1 - 3e-11 42.5 0.0 3.7e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EJS43729.1 - 6e-11 41.7 0.1 2.2e-10 39.9 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EJS43729.1 - 2.2e-07 31.0 0.3 4.3e-07 30.1 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EJS43729.1 - 7.1e-06 26.0 0.1 1.2e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EJS43729.1 - 3.6e-05 23.5 0.0 6.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EJS43729.1 - 0.022 13.9 0.0 0.08 12.1 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family Isochorismatase PF00857.15 EJS43730.1 - 4.7e-26 91.7 0.0 7.7e-26 91.0 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family DUF771 PF05595.6 EJS43730.1 - 0.091 12.6 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF771) zf-H2C2_2 PF13465.1 EJS43731.1 - 2.2e-08 33.9 13.2 1.2e-05 25.3 1.2 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EJS43731.1 - 2.2e-06 27.6 12.8 0.0043 17.2 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS43731.1 - 0.00038 20.5 12.9 0.053 13.8 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger Ribosomal_L24e PF01246.15 EJS43733.1 - 5.4e-33 112.6 0.4 5.4e-33 112.6 0.3 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e Cgr1 PF03879.9 EJS43734.1 - 4.8e-38 129.6 31.6 5.7e-38 129.4 21.9 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 EJS43734.1 - 0.37 11.0 9.7 0.44 10.8 6.7 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DRY_EERY PF09750.4 EJS43734.1 - 1.1 9.3 11.0 1.6 8.8 7.6 1.3 1 1 0 1 1 1 0 Alternative splicing regulator DUF763 PF05559.6 EJS43734.1 - 2.2 7.1 6.5 2.5 6.9 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF2948 PF11164.3 EJS43734.1 - 2.3 7.8 5.6 2.3 7.8 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2948) CAF-1_p150 PF11600.3 EJS43734.1 - 3.8 6.8 30.2 4.7 6.5 20.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spore_coat_CotO PF14153.1 EJS43734.1 - 6.3 6.1 16.6 7.4 5.9 11.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Exonuc_VII_L PF02601.10 EJS43734.1 - 8.3 5.5 10.4 8.8 5.4 7.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Herpes_TAF50 PF03326.8 EJS43735.1 - 0.2 10.5 32.1 0.28 10.0 22.2 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Glyco_hydro_63 PF03200.11 EJS43736.1 - 2.3e-216 720.3 5.4 7e-216 718.7 3.8 1.6 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 EJS43736.1 - 0.00068 18.4 0.1 0.0026 16.5 0.0 2.0 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase FlaE PF07559.9 EJS43736.1 - 0.061 13.9 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 Flagellar basal body protein FlaE Med3 PF11593.3 EJS43737.1 - 3.7e-125 418.1 51.7 4.1e-125 417.9 35.9 1.0 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal CorA PF01544.13 EJS43737.1 - 0.013 14.6 0.9 0.025 13.6 0.6 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MATH PF00917.21 EJS43737.1 - 0.31 11.2 2.5 0.69 10.1 1.7 1.5 1 0 0 1 1 1 0 MATH domain PAT1 PF09770.4 EJS43737.1 - 1.5 6.9 47.5 2.2 6.3 32.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bravo_FIGEY PF13882.1 EJS43737.1 - 2.4 9.1 8.4 0.18 12.7 0.6 2.7 2 1 0 2 2 2 0 Bravo-like intracellular region FYVE PF01363.16 EJS43738.1 - 3.5e-15 55.6 5.8 7.8e-15 54.5 4.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EJS43738.1 - 0.83 9.5 11.0 2.4 8.1 7.6 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger STT3 PF02516.9 EJS43739.1 - 2.3e-144 481.9 51.6 4e-142 474.5 33.9 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit CK_II_beta PF01214.13 EJS43740.1 - 8.2e-74 247.0 1.3 1.9e-73 245.9 0.9 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit TRAP_alpha PF03896.11 EJS43740.1 - 0.11 11.5 1.7 0.15 11.0 1.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Spt5_N PF11942.3 EJS43740.1 - 5.3 7.7 17.2 0.11 13.0 7.0 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Use1 PF09753.4 EJS43741.1 - 7.1e-09 35.4 1.5 9.4e-09 35.0 1.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF1980 PF09323.5 EJS43741.1 - 0.04 13.6 2.5 0.04 13.6 1.7 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) MRP-L28 PF09812.4 EJS43741.1 - 0.43 10.3 4.6 0.09 12.6 0.8 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 RCC1 PF00415.13 EJS43742.1 - 2.8e-60 200.3 0.0 1.1e-08 35.1 0.0 7.9 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EJS43742.1 - 1.4e-38 129.7 19.7 1.3e-08 34.1 0.0 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EJS43742.1 - 0.15 11.5 0.3 3.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Putative carbohydrate binding domain Sec1 PF00995.18 EJS43743.1 - 5.7e-144 480.8 19.2 6.5e-144 480.6 13.3 1.0 1 0 0 1 1 1 1 Sec1 family Prp18 PF02840.10 EJS43743.1 - 0.93 9.2 7.3 2.6 7.8 0.1 3.4 3 0 0 3 3 3 0 Prp18 domain ParA PF10609.4 EJS43744.1 - 5.6e-36 122.2 0.0 1.2e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EJS43744.1 - 1.7e-16 60.2 0.0 2.5e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EJS43744.1 - 1.4e-06 27.6 0.0 2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 EJS43744.1 - 1.8e-06 27.9 0.0 9.1e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EJS43744.1 - 3.9e-05 22.8 0.3 0.0031 16.6 0.0 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.1 EJS43744.1 - 0.011 15.3 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EJS43744.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EJS43744.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EJS43744.1 - 0.057 13.7 0.1 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 EJS43744.1 - 0.065 13.5 0.2 0.15 12.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EJS43744.1 - 0.16 10.8 0.1 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Zn_Tnp_IS1595 PF12760.2 EJS43744.1 - 2.7 7.8 4.7 0.39 10.5 0.1 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain SNase PF00565.12 EJS43745.1 - 1.4e-27 96.1 0.0 2.3e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MBOAT PF03062.14 EJS43746.1 - 2.5e-67 227.2 29.8 2.5e-67 227.2 20.7 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.20 EJS43747.1 - 4e-19 68.7 0.1 8.6e-19 67.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43747.1 - 2.9e-12 46.2 0.0 5.3e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NOC3p PF07540.6 EJS43747.1 - 0.04 14.1 2.2 0.089 13.0 0.2 2.5 2 0 0 2 2 2 0 Nucleolar complex-associated protein DUF544 PF04424.8 EJS43748.1 - 2.9e-34 117.4 0.8 4.4e-34 116.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF544) FHA PF00498.21 EJS43749.1 - 3.9e-09 36.5 0.0 7.7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Myc_N PF01056.13 EJS43749.1 - 0.069 12.3 7.5 0.13 11.4 5.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region SpoIIIAH PF12685.2 EJS43749.1 - 0.7 9.3 7.6 1.1 8.7 5.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein TRAP_alpha PF03896.11 EJS43749.1 - 0.92 8.4 5.3 0.84 8.5 2.9 1.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_S49_N PF08496.5 EJS43749.1 - 1 9.1 4.1 1.8 8.3 2.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNA_pol_3_Rpc31 PF11705.3 EJS43749.1 - 1.7 8.4 9.9 2.7 7.8 6.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4530 PF15039.1 EJS43749.1 - 7 6.5 9.0 13 5.7 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) DUF3682 PF12446.3 EJS43749.1 - 9.4 6.5 11.2 18 5.6 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DEAD PF00270.24 EJS43750.1 - 1e-51 174.8 0.1 2.5e-49 167.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS43750.1 - 8.2e-31 105.6 0.0 8.5e-29 99.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EJS43750.1 - 0.0012 17.3 0.1 0.0012 17.3 0.1 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 EJS43750.1 - 0.0016 17.5 14.0 0.0018 17.4 0.0 2.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EJS43750.1 - 0.0085 15.8 0.0 0.031 14.0 0.0 1.9 1 1 0 1 1 1 1 Part of AAA domain HSF_DNA-bind PF00447.12 EJS43751.1 - 4.5e-36 123.1 2.2 1.6e-35 121.4 1.5 2.0 1 0 0 1 1 1 1 HSF-type DNA-binding AFT PF08731.6 EJS43752.1 - 2.3e-48 163.0 1.8 2.3e-48 163.0 1.2 2.4 3 0 0 3 3 3 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 EJS43752.1 - 0.00048 19.6 2.1 0.55 9.8 0.0 2.5 2 0 0 2 2 2 2 MuDR family transposase RNA_POL_M_15KD PF02150.11 EJS43753.1 - 1.2e-16 60.0 4.2 1.2e-16 60.0 2.9 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 EJS43753.1 - 5.9e-15 54.6 14.8 6.5e-15 54.4 1.7 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 EJS43753.1 - 0.00026 21.2 2.5 0.0048 17.1 0.2 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar Rubredoxin PF00301.15 EJS43753.1 - 0.0069 16.2 3.4 25 4.8 0.0 4.0 4 0 0 4 4 4 0 Rubredoxin DZR PF12773.2 EJS43753.1 - 0.013 15.2 7.9 0.2 11.4 0.3 2.4 2 1 0 2 2 2 0 Double zinc ribbon zf-UBP PF02148.14 EJS43753.1 - 0.022 14.8 4.1 0.35 11.0 0.3 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DUF2387 PF09526.5 EJS43753.1 - 0.022 14.6 3.3 1 9.3 0.3 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.2 EJS43753.1 - 0.025 14.4 11.8 0.86 9.4 2.9 3.1 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EJS43753.1 - 0.05 13.5 9.0 4.5 7.3 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain C1_4 PF07975.7 EJS43753.1 - 0.076 13.0 11.5 0.28 11.1 0.7 3.0 2 1 1 3 3 3 0 TFIIH C1-like domain zf-CHY PF05495.7 EJS43753.1 - 0.085 13.0 6.5 0.42 10.8 1.0 2.3 2 0 0 2 2 2 0 CHY zinc finger Cytochrome_C7 PF14522.1 EJS43753.1 - 0.094 12.3 3.8 0.14 11.7 0.1 2.3 2 1 0 2 2 2 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 EJS43753.1 - 0.19 12.0 3.6 0.24 11.7 0.4 2.1 2 0 0 2 2 2 0 Cytochrome c3 zf-CSL PF05207.8 EJS43753.1 - 0.32 10.5 5.0 2 8.0 0.2 2.3 2 0 0 2 2 2 0 CSL zinc finger IBR PF01485.16 EJS43753.1 - 0.42 10.5 8.0 1.1 9.1 0.4 2.7 2 1 0 2 2 2 0 IBR domain DUF2296 PF10058.4 EJS43753.1 - 0.78 9.5 7.1 0.97 9.2 0.3 2.5 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) GFA PF04828.9 EJS43753.1 - 0.99 9.3 6.0 4.4 7.3 0.2 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EJS43753.1 - 1.7 8.3 9.6 3.2 7.5 0.6 3.3 3 0 0 3 3 3 0 Nudix N-terminal Mut7-C PF01927.11 EJS43753.1 - 2.1 8.3 5.3 1.6 8.7 0.1 2.3 1 1 1 2 2 2 0 Mut7-C RNAse domain Rpr2 PF04032.11 EJS43753.1 - 3.8 7.4 9.3 5.1e+02 0.6 6.5 2.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HypA PF01155.14 EJS43753.1 - 5.1 6.8 8.6 29 4.4 3.4 2.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 EJS43753.1 - 6.9 6.4 14.0 0.22 11.2 2.8 2.5 2 2 0 2 2 2 0 zinc-RING finger domain RPA_interact_C PF14768.1 EJS43753.1 - 9.4 6.7 10.8 4.1 7.8 0.9 2.5 2 2 0 2 2 2 0 Replication protein A interacting C-terminal Ribosomal_L12 PF00542.14 EJS43754.1 - 1.4e-21 76.2 13.1 2.1e-21 75.6 6.9 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Enoyl_reductase PF12241.3 EJS43754.1 - 0.018 14.0 0.2 0.026 13.5 0.1 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Ribosomal_60s PF00428.14 EJS43754.1 - 0.026 14.9 4.1 0.026 14.9 2.8 2.4 1 1 0 2 2 2 0 60s Acidic ribosomal protein NUDIX PF00293.23 EJS43755.1 - 2.4e-15 56.3 0.0 4.1e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 EJS43755.1 - 8.3e-07 28.4 0.1 1.5e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.6 EJS43755.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain TGT_C2 PF14810.1 EJS43755.1 - 0.017 14.9 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Patch-forming domain C2 of tRNA-guanine transglycosylase zf-ribbon_3 PF13248.1 EJS43755.1 - 0.042 13.0 0.1 0.12 11.5 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain SCA7 PF08313.7 EJS43756.1 - 3.1e-35 119.5 1.6 3.1e-35 119.5 1.1 2.9 3 0 0 3 3 3 1 SCA7, zinc-binding domain Glycos_transf_1 PF00534.15 EJS43757.1 - 2.1e-48 163.9 0.0 5.2e-48 162.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EJS43757.1 - 2.4e-09 37.1 0.0 5.5e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EJS43757.1 - 4e-07 30.2 0.0 0.00011 22.3 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EJS43757.1 - 1.5e-05 25.1 0.0 4.8e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain DUF3524 PF12038.3 EJS43757.1 - 0.045 13.3 0.2 0.11 11.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) PseudoU_synth_1 PF01416.15 EJS43758.1 - 1.8e-25 89.3 0.0 1.4e-12 47.9 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF3268 PF11672.3 EJS43758.1 - 0.094 12.8 0.2 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) CPSase_L_D2 PF02786.12 EJS43759.1 - 2.8e-85 284.8 0.1 5.3e-85 283.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EJS43759.1 - 1.3e-66 223.8 0.0 2.2e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EJS43759.1 - 5e-36 123.1 0.1 1.2e-35 121.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EJS43759.1 - 2.2e-30 104.7 0.0 6.9e-30 103.1 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EJS43759.1 - 2.9e-29 102.4 0.1 6.5e-29 101.2 0.1 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 EJS43759.1 - 6.2e-19 67.4 2.2 6.2e-19 67.4 1.5 2.2 3 0 0 3 3 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EJS43759.1 - 6.4e-19 67.8 0.1 4.9e-18 64.9 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EJS43759.1 - 2.9e-16 59.7 0.1 6e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EJS43759.1 - 5.4e-08 32.4 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EJS43759.1 - 1.9e-07 30.6 0.0 3.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EJS43759.1 - 4.3e-07 29.5 2.2 0.015 14.9 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EJS43759.1 - 2.3e-05 24.2 0.0 5.8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EJS43759.1 - 0.00015 21.3 0.0 0.00039 19.9 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 EJS43759.1 - 0.00041 20.6 0.4 0.22 11.8 0.0 3.1 3 0 0 3 3 2 1 HlyD family secretion protein HlyD PF00529.15 EJS43759.1 - 0.0014 17.9 0.7 0.34 10.1 0.0 2.8 3 0 0 3 3 3 1 HlyD family secretion protein HlyD_2 PF12700.2 EJS43759.1 - 0.015 14.4 0.2 3 6.9 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein RnfC_N PF13375.1 EJS43759.1 - 0.079 12.6 3.8 0.6 9.8 1.0 3.0 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DASH_Duo1 PF08651.5 EJS43760.1 - 6e-27 93.0 3.8 6e-27 93.0 2.6 2.1 2 0 0 2 2 2 1 DASH complex subunit Duo1 Cas_DxTHG PF09455.5 EJS43760.1 - 0.028 13.5 2.8 0.036 13.2 1.9 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Bac_thur_toxin PF01338.13 EJS43760.1 - 0.04 13.1 1.7 0.057 12.6 1.2 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis toxin Kinetochor_Ybp2 PF08568.5 EJS43761.1 - 2.7e-133 445.4 16.0 3.1e-133 445.3 11.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin BCDHK_Adom3 PF10436.4 EJS43762.1 - 2.1e-35 121.6 1.2 3.3e-35 121.0 0.6 1.5 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EJS43762.1 - 1.6e-08 34.2 0.0 3.9e-07 29.7 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CBS PF00571.23 EJS43763.1 - 7.2e-21 73.7 0.5 4.6e-05 23.1 0.1 5.3 5 0 0 5 5 5 5 CBS domain FA_desaturase PF00487.19 EJS43764.1 - 1.2e-18 67.5 19.4 1.2e-18 67.5 13.4 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EJS43764.1 - 2.1e-14 53.0 0.0 6.9e-14 51.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Cornichon PF03311.9 EJS43765.1 - 1e-51 174.3 7.8 1.2e-51 174.2 5.4 1.0 1 0 0 1 1 1 1 Cornichon protein MIF4G PF02854.14 EJS43766.1 - 2.9e-47 160.7 0.1 2.9e-47 160.7 0.1 1.8 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.3 EJS43766.1 - 2.4e-25 88.2 1.8 9.9e-25 86.2 1.2 2.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 AAA PF00004.24 EJS43767.1 - 1.5e-43 148.1 0.0 2.9e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EJS43767.1 - 3.9e-07 29.8 0.0 1.8e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EJS43767.1 - 5.3e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EJS43767.1 - 3.8e-06 27.0 0.1 0.00028 21.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EJS43767.1 - 2.4e-05 24.4 0.0 7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EJS43767.1 - 4e-05 24.4 0.2 0.00013 22.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EJS43767.1 - 0.00014 20.9 0.0 0.00025 20.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EJS43767.1 - 0.00015 21.4 0.1 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EJS43767.1 - 0.00025 20.5 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EJS43767.1 - 0.00058 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EJS43767.1 - 0.0018 18.2 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EJS43767.1 - 0.0019 18.1 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EJS43767.1 - 0.0028 16.7 0.0 0.0067 15.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin DUF2072 PF09845.4 EJS43767.1 - 0.0032 17.3 1.6 0.0089 15.9 1.1 1.8 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_3 PF07726.6 EJS43767.1 - 0.005 16.4 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EJS43767.1 - 0.0077 16.5 1.2 0.031 14.5 0.0 2.6 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 EJS43767.1 - 0.008 14.9 0.2 0.022 13.4 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus Mg_chelatase PF01078.16 EJS43767.1 - 0.011 14.9 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EJS43767.1 - 0.012 14.8 0.0 0.046 12.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 EJS43767.1 - 0.027 13.9 0.0 0.15 11.5 0.0 2.2 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.1 EJS43767.1 - 0.029 13.7 0.1 0.1 12.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EJS43767.1 - 0.029 13.9 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EJS43767.1 - 0.032 14.3 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EJS43767.1 - 0.064 12.9 0.0 0.35 10.4 0.0 2.1 1 1 1 2 2 2 0 NACHT domain DUF815 PF05673.8 EJS43767.1 - 0.083 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EJS43767.1 - 0.086 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Glyco_tran_28_C PF04101.11 EJS43768.1 - 2.9e-32 111.6 0.0 5.7e-32 110.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EJS43768.1 - 0.037 13.2 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 Arrestin_N PF00339.24 EJS43769.1 - 1.4e-28 99.5 0.1 5.7e-28 97.6 0.2 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EJS43769.1 - 1.9e-10 41.0 7.2 2.7e-08 34.0 0.1 3.1 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Mcm10 PF09332.6 EJS43769.1 - 0.71 9.1 5.1 0.35 10.1 1.7 1.7 2 0 0 2 2 2 0 Mcm10 replication factor RRM_1 PF00076.17 EJS43770.1 - 3.3e-20 71.5 0.0 6e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS43770.1 - 5.9e-15 55.0 0.0 1.3e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS43770.1 - 6.3e-11 41.9 0.0 1.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EJS43770.1 - 3.8e-07 29.2 0.8 9.6e-07 27.9 0.5 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal Menin PF05053.8 EJS43770.1 - 1.9 6.5 9.8 2.7 6.0 6.8 1.1 1 0 0 1 1 1 0 Menin Spore_YhcN_YlaJ PF09580.5 EJS43770.1 - 2.2 8.3 16.6 3.1 7.8 11.5 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) TFIIS_M PF07500.9 EJS43771.1 - 2e-27 95.5 0.3 2e-27 95.5 0.2 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EJS43771.1 - 3.2e-17 61.8 6.3 3.2e-17 61.8 4.4 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EJS43771.1 - 1.5e-15 56.4 1.0 4.1e-15 55.0 0.7 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosomal_S27 PF01599.14 EJS43771.1 - 0.25 11.1 2.5 2.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S27a Gly_radical PF01228.16 EJS43771.1 - 0.47 10.8 2.8 1.2 9.5 0.2 2.7 2 2 1 3 3 3 0 Glycine radical Zn_Tnp_IS1595 PF12760.2 EJS43771.1 - 1.6 8.6 5.5 6.1 6.7 3.9 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain ALAD PF00490.16 EJS43772.1 - 3e-115 384.5 0.0 3.6e-115 384.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase WD40 PF00400.27 EJS43774.1 - 2e-21 74.9 16.6 6.8e-07 28.9 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EJS43774.1 - 0.00048 19.8 1.4 0.16 11.6 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A CBS PF00571.23 EJS43775.1 - 4.3e-29 100.0 3.9 7.5e-13 48.0 0.1 4.2 4 0 0 4 4 4 4 CBS domain Foamy_BEL PF03274.9 EJS43775.1 - 0.087 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein OPT PF03169.10 EJS43776.1 - 3.1e-177 590.7 18.1 3.5e-177 590.6 12.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SLD3 PF08639.5 EJS43777.1 - 1.1e-93 314.6 18.3 2.3e-93 313.5 12.7 1.6 1 1 0 1 1 1 1 DNA replication regulator SLD3 TAF PF02969.12 EJS43778.1 - 9.8e-30 102.3 0.2 2.4e-29 101.0 0.2 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 EJS43778.1 - 1.1e-29 102.4 0.0 5.4e-29 100.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) Histone PF00125.19 EJS43778.1 - 0.00046 20.2 0.2 0.0027 17.7 0.1 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.9 EJS43778.1 - 0.00076 18.8 0.0 0.002 17.4 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CENP-S PF15630.1 EJS43778.1 - 0.0075 16.4 1.7 0.6 10.3 0.0 3.2 3 0 0 3 3 3 1 Kinetochore component CENP-S TFIID-31kDa PF02291.10 EJS43778.1 - 0.045 13.5 1.2 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.18 EJS43778.1 - 0.097 12.7 0.5 0.43 10.6 0.1 2.3 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CDC27 PF09507.5 EJS43779.1 - 4.6 6.3 29.8 5.6 6.0 20.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EF-hand_7 PF13499.1 EJS43780.1 - 7.8e-14 51.5 0.9 3.7e-09 36.5 0.7 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EJS43780.1 - 2.9e-09 36.0 4.4 0.0027 17.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EJS43780.1 - 7.8e-09 35.0 1.7 2.8e-06 26.8 0.2 3.6 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 EJS43780.1 - 1.2e-08 33.6 6.4 0.00069 18.7 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EJS43780.1 - 2.1e-07 30.7 0.1 0.0094 15.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EJS43780.1 - 0.011 15.0 3.0 0.61 9.5 0.0 3.3 3 0 0 3 3 3 0 EF hand UPF0154 PF03672.8 EJS43780.1 - 0.068 12.7 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF965 PF06135.7 EJS43780.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) tRNA_bind PF01588.15 EJS43781.1 - 2e-28 98.0 0.0 3.4e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Viral_protease PF08715.5 EJS43781.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Papain like viral protease NARP1 PF12569.3 EJS43781.1 - 0.15 10.8 10.3 0.2 10.3 7.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 EJS43781.1 - 0.85 9.4 6.7 1.4 8.7 4.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HD_3 PF13023.1 EJS43782.1 - 5.3e-35 120.6 0.1 6.6e-35 120.2 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EJS43782.1 - 3.5e-06 27.0 0.0 7.2e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 HD domain HD_2 PF12917.2 EJS43782.1 - 0.022 14.5 0.2 0.028 14.2 0.2 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme WD40 PF00400.27 EJS43783.1 - 2.6e-35 119.0 19.2 1.4e-08 34.3 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat MMR_HSR1 PF01926.18 EJS43784.1 - 1.7e-16 60.1 0.3 1.5e-14 53.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EJS43784.1 - 3.5e-07 29.6 0.2 1.5e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EJS43784.1 - 0.00098 18.3 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EJS43784.1 - 0.0025 16.9 0.1 0.0053 15.9 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EJS43784.1 - 0.0043 17.5 0.3 0.1 13.0 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EJS43784.1 - 0.12 12.1 4.7 0.068 12.9 0.4 2.7 3 1 0 3 3 3 0 Dynamin family WAC_Acf1_DNA_bd PF10537.4 EJS43785.1 - 1.2e-36 124.8 0.5 4.2e-36 123.1 0.3 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EJS43785.1 - 7.6e-18 64.0 0.1 6.8e-17 60.9 0.0 2.3 2 0 0 2 2 2 1 DDT domain WHIM2 PF15613.1 EJS43785.1 - 3.4e-13 48.9 1.0 9.6e-13 47.5 0.1 2.3 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EJS43785.1 - 0.052 13.5 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 mRNA_cap_enzyme PF01331.14 EJS43786.1 - 8.1e-64 214.8 0.0 1.7e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EJS43786.1 - 3.5e-21 75.4 0.5 2.4e-20 72.8 0.4 2.2 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EJS43786.1 - 1.5e-07 31.0 0.0 1.1e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DUF4420 PF14390.1 EJS43786.1 - 0.0091 14.8 0.1 0.018 13.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4420) DnaJ PF00226.26 EJS43787.1 - 1.8e-16 59.6 0.9 3.8e-16 58.5 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain Scs3p PF10261.4 EJS43788.1 - 3.8e-80 268.3 9.5 4.5e-80 268.1 6.6 1.0 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM MTHFR PF02219.12 EJS43789.1 - 7.4e-125 415.7 0.0 1.1e-124 415.2 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Mon1 PF03164.9 EJS43790.1 - 5.8e-165 548.9 6.1 7.1e-165 548.6 4.2 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Ribosomal_S5 PF00333.15 EJS43791.1 - 7.5e-29 99.2 6.2 1e-28 98.8 2.2 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EJS43791.1 - 1.2e-21 75.7 0.1 2e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain E3_binding PF02817.12 EJS43791.1 - 0.23 11.1 1.3 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 e3 binding domain Nab2 PF11517.3 EJS43792.1 - 1.9e-49 166.2 3.0 2.8e-49 165.6 2.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.1 EJS43792.1 - 2e-17 62.4 67.4 7.8e-06 25.6 1.0 7.5 7 1 0 7 7 7 5 Zinc finger C-x8-C-x5-C-x3-H type SHOCT PF09851.4 EJS43792.1 - 0.058 12.8 0.7 0.15 11.6 0.5 1.7 1 0 0 1 1 1 0 Short C-terminal domain Neur_chan_memb PF02932.11 EJS43792.1 - 0.092 12.6 2.3 0.22 11.3 1.6 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Synuclein PF01387.12 EJS43792.1 - 0.18 11.6 2.1 0.36 10.7 1.5 1.4 1 0 0 1 1 1 0 Synuclein BAF1_ABF1 PF04684.8 EJS43792.1 - 0.21 10.4 8.2 0.28 9.9 5.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2391 PF09622.5 EJS43792.1 - 0.22 10.6 0.7 0.3 10.2 0.5 1.1 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) Lin-8 PF03353.10 EJS43792.1 - 0.51 9.5 7.3 0.99 8.6 5.1 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.4 EJS43792.1 - 0.93 7.6 26.6 1.6 6.8 18.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 EJS43792.1 - 2.2 5.8 19.3 3.1 5.3 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UPF0560 PF10577.4 EJS43792.1 - 2.3 6.3 10.2 3.3 5.8 7.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Flu_NS2 PF00601.14 EJS43793.1 - 0.064 13.4 0.2 6.6 7.0 0.0 2.2 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) DUF3783 PF12646.2 EJS43793.1 - 0.24 11.1 1.0 0.69 9.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) HA2 PF04408.18 EJS43794.1 - 9.9e-27 92.9 0.0 2.4e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EJS43794.1 - 6.2e-26 90.4 0.0 1.4e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EJS43794.1 - 1e-11 44.4 0.0 2.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EJS43794.1 - 1.9e-09 37.2 0.2 3.3e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EJS43794.1 - 2.4e-06 27.7 0.1 9.8e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EJS43794.1 - 0.00021 20.8 0.1 0.00053 19.4 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EJS43794.1 - 0.0004 20.2 0.2 0.018 14.8 0.2 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EJS43794.1 - 0.00095 18.9 0.1 0.0018 18.0 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_23 PF13476.1 EJS43794.1 - 0.0081 16.5 0.6 0.054 13.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EJS43794.1 - 0.017 13.9 0.0 0.04 12.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EJS43794.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EJS43794.1 - 0.086 12.0 0.0 0.32 10.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.1 EJS43794.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain EMP24_GP25L PF01105.19 EJS43795.1 - 1.7e-43 148.4 0.1 2e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Yip1 PF04893.12 EJS43796.1 - 4.3e-13 49.1 10.2 5.7e-13 48.7 7.1 1.2 1 0 0 1 1 1 1 Yip1 domain O-antigen_lig PF13425.1 EJS43796.1 - 5.6 6.9 14.3 1.4 8.8 3.9 2.2 1 1 1 2 2 2 0 O-antigen ligase like membrane protein Kelch_6 PF13964.1 EJS43797.1 - 7.4e-16 57.5 0.3 8.2e-07 28.9 0.0 5.1 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EJS43797.1 - 7.6e-14 51.2 2.0 8.7e-05 22.2 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EJS43797.1 - 8.3e-14 50.8 1.9 4.4e-06 26.1 0.0 4.7 4 1 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EJS43797.1 - 4.8e-11 42.5 0.0 0.0019 18.2 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EJS43797.1 - 8.5e-09 34.8 0.9 9.7e-06 25.1 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 EJS43797.1 - 0.0015 18.3 0.1 0.12 12.3 0.0 3.2 3 0 0 3 3 3 1 Kelch motif D-ser_dehydrat PF14031.1 EJS43798.1 - 7.6e-18 64.4 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EJS43798.1 - 4.2e-11 42.8 0.0 6.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3554 PF12074.3 EJS43799.1 - 4.8e-58 197.1 1.2 4.8e-58 197.1 0.8 6.9 7 2 0 7 7 7 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 EJS43799.1 - 3.9e-36 123.1 21.0 4.6e-08 33.2 0.0 12.9 7 4 4 12 12 12 8 HEAT repeats HEAT PF02985.17 EJS43799.1 - 2e-32 108.3 20.7 0.0061 16.5 0.0 19.3 21 0 0 21 21 21 8 HEAT repeat HEAT_EZ PF13513.1 EJS43799.1 - 4.7e-28 96.9 23.1 0.01 16.2 0.0 17.5 11 3 5 18 18 18 7 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EJS43799.1 - 2.5e-10 40.5 8.9 0.066 13.5 0.0 10.0 10 1 1 11 11 11 2 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 EJS43799.1 - 0.0062 16.4 10.8 1.9 8.5 0.0 8.0 10 0 0 10 10 10 1 Rix1 complex component involved in 60S ribosome maturation DUF937 PF06078.6 EJS43799.1 - 0.06 13.5 0.3 15 5.8 0.0 4.2 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF937) Hist_deacetyl PF00850.14 EJS43801.1 - 9.9e-83 277.9 0.0 1.3e-82 277.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MT-A70 PF05063.9 EJS43802.1 - 1.9e-56 190.3 0.2 3.7e-56 189.4 0.1 1.5 1 0 0 1 1 1 1 MT-A70 AAA_21 PF13304.1 EJS43802.1 - 0.011 15.7 1.8 0.011 15.7 1.2 2.1 2 0 0 2 2 2 0 AAA domain COX6A PF02046.10 EJS43803.1 - 4.6e-40 136.1 0.6 4.9e-40 136.0 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2741 PF10890.3 EJS43803.1 - 0.033 14.3 0.1 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) WD40 PF00400.27 EJS43804.1 - 1.5e-16 59.5 0.8 0.0014 18.4 0.0 7.3 7 1 0 7 7 7 5 WD domain, G-beta repeat FRG2 PF15315.1 EJS43804.1 - 2.6 7.9 10.4 5.5 6.9 7.2 1.5 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Ribosomal_S26e PF01283.14 EJS43805.1 - 1.8e-50 169.9 7.8 2.1e-50 169.7 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1101 PF06503.6 EJS43805.1 - 0.019 13.8 0.1 0.02 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) COX5B PF01215.14 EJS43806.1 - 1.6e-61 205.9 0.0 1.9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb 2-Hacid_dh_C PF02826.14 EJS43807.1 - 1.3e-32 112.4 0.0 1.8e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EJS43807.1 - 8.8e-06 25.2 0.0 0.00076 18.9 0.0 2.7 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EJS43807.1 - 0.00017 21.4 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EJS43807.1 - 0.0038 16.6 0.1 0.013 14.8 0.0 2.0 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EJS43807.1 - 0.045 12.6 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EJS43807.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cys_Met_Meta_PP PF01053.15 EJS43808.1 - 4.7e-128 426.7 0.0 5.4e-128 426.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 EJS43808.1 - 0.082 11.1 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase DUF3543 PF12063.3 EJS43809.1 - 1.2e-63 214.5 10.7 3.6e-63 212.9 4.8 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EJS43809.1 - 7.4e-61 205.5 0.0 2.6e-60 203.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43809.1 - 4.2e-45 153.8 0.0 8.2e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43809.1 - 0.0098 14.8 0.1 0.17 10.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EJS43809.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EJS43810.1 - 7.2e-63 212.1 0.0 9.5e-63 211.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43810.1 - 2.2e-31 108.9 0.0 3.7e-31 108.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43810.1 - 1.1e-07 31.0 0.0 2.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EJS43810.1 - 0.0064 15.3 0.1 0.017 13.9 0.0 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 Bud13 PF09736.4 EJS43812.1 - 7.9e-25 87.8 3.7 7.9e-25 87.8 2.6 3.0 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Nucleoporin_FG PF13634.1 EJS43813.1 - 4.5e-24 84.8 125.7 2.7e-11 43.6 27.2 4.5 2 1 2 4 4 4 3 Nucleoporin FG repeat region XH PF03469.9 EJS43813.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 XH domain DUF1664 PF07889.7 EJS43813.1 - 0.063 13.0 3.5 0.3 10.8 0.6 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) FAM117 PF15388.1 EJS43813.1 - 0.54 9.4 5.5 0.16 11.1 0.4 2.0 2 0 0 2 2 2 0 Protein Family FAM117 Lzipper-MIP1 PF14389.1 EJS43813.1 - 6.6 6.9 10.1 5.3 7.2 1.4 2.8 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Sua5_yciO_yrdC PF01300.13 EJS43815.1 - 2.1e-47 160.6 0.0 3.8e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EJS43815.1 - 2.1e-31 108.6 0.0 3.6e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding E1-E2_ATPase PF00122.15 EJS43816.1 - 2.6e-78 262.2 0.6 5.3e-78 261.2 0.4 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EJS43816.1 - 3.2e-47 160.3 1.4 3.2e-47 160.3 1.0 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EJS43816.1 - 1.1e-30 107.6 0.0 2.7e-30 106.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EJS43816.1 - 4.9e-19 68.0 0.1 1.1e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EJS43816.1 - 4e-17 63.0 0.0 8.1e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EJS43816.1 - 1.1e-15 56.8 0.0 3.2e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EJS43816.1 - 3.3e-05 23.5 0.3 0.0029 17.2 0.2 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Copper-fist PF00649.13 EJS43817.1 - 6.5e-21 73.2 1.5 6.5e-21 73.2 1.0 2.4 1 1 1 2 2 2 1 Copper fist DNA binding domain SNF2_N PF00176.18 EJS43818.1 - 3.7e-71 239.3 0.0 5.3e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EJS43818.1 - 1.4e-54 184.8 6.5 3e-54 183.7 4.5 1.6 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EJS43818.1 - 2.4e-13 49.7 0.0 6.4e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EJS43818.1 - 3e-08 32.8 2.6 4.2e-08 32.3 0.1 2.5 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EJS43818.1 - 1.5e-05 24.5 0.0 3.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EJS43818.1 - 0.002 18.0 0.2 0.0079 16.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1170 PF06663.8 EJS43818.1 - 0.018 14.9 0.1 0.071 13.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1170) Yip1 PF04893.12 EJS43819.1 - 1.1e-06 28.3 0.0 2e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Yip1 domain DUF2427 PF10348.4 EJS43819.1 - 3.3e-05 23.4 1.2 8.9e-05 22.0 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) OCD_Mu_crystall PF02423.10 EJS43820.1 - 1.8e-08 33.5 0.0 0.0025 16.6 0.0 2.2 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Glyco_hydro_38 PF01074.17 EJS43821.1 - 5.1e-85 285.0 0.3 7.8e-85 284.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EJS43821.1 - 5.2e-74 249.6 0.4 7.5e-74 249.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EJS43821.1 - 4.3e-25 87.7 0.0 1e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Med5 PF08689.5 EJS43822.1 - 0 1018.9 50.6 0 1018.7 35.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SNF2_N PF00176.18 EJS43823.1 - 3.1e-71 239.5 3.9 3.1e-71 239.5 2.7 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EJS43823.1 - 5.2e-53 178.8 26.7 5.2e-53 178.8 18.5 4.2 3 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 EJS43823.1 - 9.7e-14 50.9 0.0 3.2e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chorismate_synt PF01264.16 EJS43824.1 - 1.2e-133 444.8 0.0 1.4e-133 444.6 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ribosomal_L6 PF00347.18 EJS43825.1 - 2.8e-29 101.4 11.0 1.4e-15 57.5 3.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 UAF_Rrn10 PF05234.6 EJS43825.1 - 0.079 12.9 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 UAF complex subunit Rrn10 RF-1 PF00472.15 EJS43826.1 - 2.4e-39 133.6 4.0 4.6e-39 132.7 2.8 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EJS43826.1 - 2.1e-29 101.6 0.1 7.4e-29 99.8 0.0 2.0 2 0 0 2 2 2 1 PCRF domain Dynamin_N PF00350.18 EJS43826.1 - 0.019 14.8 0.1 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Dynamin family DUF2543 PF10820.3 EJS43826.1 - 0.31 11.0 2.4 0.55 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) HECT PF00632.20 EJS43827.1 - 6.9e-88 294.8 0.4 1.5e-87 293.7 0.3 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2422 PF10337.4 EJS43828.1 - 1e-91 308.0 1.0 1e-91 308.0 0.7 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EJS43828.1 - 4e-13 49.4 14.1 4e-13 49.4 9.7 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EJS43828.1 - 1.3e-08 33.9 5.9 2e-06 26.7 1.1 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 EJS43828.1 - 0.00053 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC PF04632.7 EJS43828.1 - 0.051 12.0 6.0 0.093 11.1 4.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF939 PF06081.6 EJS43828.1 - 0.42 10.4 8.7 0.18 11.6 1.5 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF939) TRP PF06011.7 EJS43829.1 - 2e-147 491.3 42.5 2.6e-147 490.9 29.4 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EJS43829.1 - 9.2e-44 148.9 1.4 1.6e-43 148.1 0.9 1.4 1 0 0 1 1 1 1 ML-like domain Aminotran_1_2 PF00155.16 EJS43830.1 - 2.6e-20 72.6 0.0 3.5e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EJS43830.1 - 0.051 12.7 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EJS43830.1 - 0.1 11.5 0.1 0.35 9.8 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family MCM PF00493.18 EJS43831.1 - 4e-138 459.7 0.8 5.7e-138 459.2 0.5 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EJS43831.1 - 1.1e-19 71.1 1.7 1.9e-19 70.3 0.0 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EJS43831.1 - 2.6e-07 30.0 0.0 7.7e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EJS43831.1 - 0.0037 16.7 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EJS43831.1 - 0.013 15.0 0.1 0.047 13.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EJS43831.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UAA PF08449.6 EJS43832.1 - 5.9e-18 64.8 25.7 7.3e-18 64.5 17.8 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EJS43832.1 - 1.4e-09 37.7 9.6 1.4e-09 37.7 6.7 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EJS43832.1 - 0.00044 20.2 30.4 0.056 13.4 9.8 2.4 2 1 0 2 2 2 2 EamA-like transporter family PHO4 PF01384.15 EJS43832.1 - 0.27 9.8 14.6 0.044 12.4 1.7 2.6 2 1 0 2 2 2 0 Phosphate transporter family HAD_2 PF13419.1 EJS43833.1 - 2.2e-23 83.4 0.0 3e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EJS43833.1 - 0.0048 16.5 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 Acid Phosphatase Hydrolase PF00702.21 EJS43833.1 - 0.0065 16.9 0.0 0.062 13.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF3 PF01784.13 EJS43834.1 - 9.5e-64 215.2 0.1 1.2e-63 214.9 0.1 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Beta-Casp PF10996.3 EJS43834.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 Beta-Casp domain tRNA-synt_1c_C PF03950.13 EJS43835.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain AflR PF08493.5 EJS43835.1 - 0.34 9.8 4.4 0.79 8.6 3.1 1.5 1 0 0 1 1 1 0 Aflatoxin regulatory protein Kinesin PF00225.18 EJS43836.1 - 5.1e-113 377.1 1.7 5.1e-113 377.1 1.2 1.7 2 0 0 2 2 2 1 Kinesin motor domain Cyclin PF08613.6 EJS43837.1 - 1.7e-05 25.3 0.2 1.7e-05 25.3 0.1 2.2 2 0 0 2 2 2 1 Cyclin LLC1 PF14945.1 EJS43837.1 - 0.023 14.9 1.0 0.059 13.6 0.7 1.6 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein WD40 PF00400.27 EJS43838.1 - 6e-15 54.4 23.2 1.7e-07 30.8 1.7 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EJS43838.1 - 0.13 12.0 0.1 9.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF2415 PF10313.4 EJS43838.1 - 0.13 11.9 0.7 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) ATP_bind_3 PF01171.15 EJS43839.1 - 5.2e-18 65.1 0.0 8.9e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EJS43839.1 - 6.7e-05 23.1 0.1 0.00022 21.4 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EJS43839.1 - 0.0079 14.7 0.0 0.015 13.9 0.0 1.4 1 1 0 1 1 1 1 tRNA methyl transferase MU117 PF15474.1 EJS43839.1 - 0.019 15.4 1.7 0.019 15.4 1.2 1.9 2 0 0 2 2 2 0 Meiotically up-regulated gene family PAPS_reduct PF01507.14 EJS43839.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Ribosomal_S14 PF00253.16 EJS43839.1 - 7.4 6.0 11.5 0.6 9.5 0.9 3.2 3 0 0 3 3 3 0 Ribosomal protein S14p/S29e Ras PF00071.17 EJS43840.1 - 8.1e-60 200.8 0.3 9.6e-60 200.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS43840.1 - 6.7e-20 71.7 0.1 9.6e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS43840.1 - 3.3e-13 49.2 0.0 4.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EJS43840.1 - 1.6e-07 31.3 0.1 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.1 EJS43840.1 - 7.2e-06 25.2 0.1 7.9e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 EJS43840.1 - 1.1e-05 24.9 0.1 2.4e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EJS43840.1 - 0.00032 19.9 0.0 0.00042 19.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EJS43840.1 - 0.00055 19.1 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EJS43840.1 - 0.0022 17.2 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit KAP_NTPase PF07693.9 EJS43840.1 - 0.0024 16.9 0.0 0.0032 16.5 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 EJS43840.1 - 0.0096 16.0 0.1 0.022 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EJS43840.1 - 0.02 14.9 0.2 0.084 12.8 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EJS43840.1 - 0.026 13.7 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 EJS43840.1 - 0.03 14.5 0.3 0.051 13.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EJS43840.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EJS43840.1 - 0.067 12.2 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_14 PF13173.1 EJS43840.1 - 0.075 12.9 0.1 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain TraG_N PF07916.6 EJS43840.1 - 0.097 11.1 0.1 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region AMPKBI PF04739.10 EJS43841.1 - 9.9e-32 108.8 3.9 9.9e-32 108.8 2.7 2.1 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Bact_transglu_N PF08379.5 EJS43841.1 - 0.028 14.6 0.1 0.17 12.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial transglutaminase-like N-terminal region SPT16 PF08644.6 EJS43842.1 - 2.2e-51 173.7 1.3 3.7e-51 172.9 0.2 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EJS43842.1 - 5.8e-49 165.7 3.4 2.8e-48 163.5 0.1 3.0 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EJS43842.1 - 1.3e-23 83.7 0.0 2.1e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EJS43842.1 - 2.4e-19 69.0 0.6 2.8e-18 65.6 0.1 2.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Clathrin PF00637.15 EJS43843.1 - 5.6e-199 651.7 61.3 1.6e-32 112.0 0.1 8.5 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EJS43843.1 - 2.9e-25 87.9 1.0 1e-24 86.2 0.2 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 EJS43843.1 - 3.2e-18 64.6 2.8 0.00025 21.1 0.1 5.7 5 0 0 5 5 5 5 Clathrin propeller repeat Clathrin-link PF09268.5 EJS43843.1 - 2.6e-09 35.8 0.4 2.6e-09 35.8 0.2 3.2 4 0 0 4 4 4 1 Clathrin, heavy-chain linker TPR_7 PF13176.1 EJS43843.1 - 0.0092 15.7 10.6 8.2 6.4 0.0 7.5 9 0 0 9 9 9 2 Tetratricopeptide repeat ACOX PF01756.14 EJS43844.1 - 3e-53 179.9 0.0 6.2e-53 178.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EJS43844.1 - 1.8e-16 59.3 0.2 3.8e-16 58.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EJS43844.1 - 4.8e-11 43.0 0.0 1.9e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 EJS43844.1 - 0.0014 18.7 0.0 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_S10 PF00450.17 EJS43845.1 - 3e-106 356.0 0.5 4.4e-106 355.5 0.3 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase CDC45 PF02724.9 EJS43845.1 - 0.003 15.6 30.2 0.0055 14.8 20.9 1.4 1 0 0 1 1 1 1 CDC45-like protein DUF2015 PF09435.5 EJS43845.1 - 0.0053 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Gag_spuma PF03276.9 EJS43845.1 - 0.35 9.1 3.6 0.52 8.5 2.5 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Hid1 PF12722.2 EJS43845.1 - 1.4 6.5 13.0 2.1 5.9 9.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 EJS43845.1 - 2.2 5.8 13.8 3.2 5.3 9.5 1.3 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 EJS43846.1 - 6.1e-60 202.8 0.9 7e-60 202.6 0.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1469 PF07332.6 EJS43846.1 - 0.17 11.6 0.2 0.17 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Hexokinase_2 PF03727.11 EJS43847.1 - 1.3e-98 329.0 0.0 1.7e-98 328.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EJS43847.1 - 3.5e-86 287.7 0.0 4.7e-86 287.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 EJS43847.1 - 0.007 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Ppx-GppA PF02541.11 EJS43848.1 - 2.9e-95 318.7 0.0 3.7e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family PDEase_II PF02112.10 EJS43849.1 - 1.3e-107 359.6 0.0 1.5e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EJS43849.1 - 1.9e-08 34.0 0.1 2.8e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EJS43849.1 - 0.085 12.5 1.0 0.18 11.4 0.7 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Brr6_like_C_C PF10104.4 EJS43850.1 - 1.4e-42 144.3 2.2 1.7e-42 144.1 1.5 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Glycoprotein PF03409.10 EJS43850.1 - 0.005 15.6 0.0 0.0087 14.8 0.0 1.3 1 0 0 1 1 1 1 Transmembrane glycoprotein tRNA-synt_1c PF00749.16 EJS43851.1 - 2.4e-118 394.3 0.1 3.2e-118 393.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EJS43851.1 - 8.2e-39 133.0 0.9 2.2e-38 131.6 0.6 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EJS43851.1 - 0.00016 22.0 0.0 0.00049 20.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EJS43851.1 - 0.0066 16.3 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EJS43851.1 - 0.03 14.3 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Plus-3 PF03126.13 EJS43852.1 - 5e-35 119.8 0.1 1.9e-34 117.9 0.1 2.1 1 0 0 1 1 1 1 Plus-3 domain Ank_2 PF12796.2 EJS43853.1 - 2.5e-12 46.9 0.0 3.9e-09 36.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EJS43853.1 - 3e-12 45.7 0.0 0.00018 21.1 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EJS43853.1 - 1.6e-09 37.7 0.1 0.00044 20.3 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EJS43853.1 - 1.8e-08 33.8 0.0 0.0011 19.0 0.0 3.8 3 2 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EJS43853.1 - 4.7e-08 33.3 0.4 0.00011 22.6 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) IBN_N PF03810.14 EJS43854.1 - 2.7e-10 39.9 3.4 2.1e-09 37.1 0.1 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain DUF592 PF04574.8 EJS43854.1 - 0.28 10.7 4.6 0.12 11.9 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF592) APC10 PF03256.11 EJS43855.1 - 3.8e-64 215.8 0.0 5e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EJS43855.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.4 1 1 0 1 1 1 0 F5/8 type C domain Cse1 PF08506.5 EJS43856.1 - 1e-171 570.5 13.7 1.7e-171 569.8 8.7 1.9 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 EJS43856.1 - 9.8e-106 353.6 11.6 9.8e-106 353.6 8.1 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EJS43856.1 - 1.8e-18 66.2 0.1 1.1e-15 57.2 0.0 3.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EJS43856.1 - 0.0016 18.3 0.6 0.023 14.6 0.0 3.3 2 1 0 2 2 2 1 Exportin 1-like protein CBFB_NFYA PF02045.10 EJS43857.1 - 6.2e-28 97.1 9.0 1.7e-27 95.6 6.2 1.8 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B GIDA PF01134.17 EJS43858.1 - 1.2e-157 524.8 0.0 1.6e-157 524.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EJS43858.1 - 9.5e-20 70.4 0.0 6e-19 67.8 0.0 2.4 2 0 0 2 2 2 1 GidA associated domain 3 FAD_oxidored PF12831.2 EJS43858.1 - 9.3e-08 31.5 0.4 1.5e-07 30.8 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EJS43858.1 - 4.2e-07 30.0 0.3 9.5e-07 28.8 0.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EJS43858.1 - 2.5e-06 26.6 1.0 0.015 14.1 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EJS43858.1 - 0.00041 20.1 0.0 0.001 18.8 0.0 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EJS43858.1 - 0.00047 19.1 1.5 0.0035 16.2 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EJS43858.1 - 0.0025 18.2 0.2 0.0056 17.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EJS43858.1 - 0.045 12.7 0.3 0.071 12.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.16 EJS43858.1 - 0.058 12.9 0.2 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EJS43858.1 - 0.07 12.0 0.4 0.32 9.8 0.3 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EJS43858.1 - 0.088 13.0 0.1 0.68 10.2 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EJS43858.1 - 0.21 11.2 0.3 0.36 10.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EJS43858.1 - 0.25 9.7 5.5 0.21 10.0 0.9 2.5 3 0 0 3 3 3 0 HI0933-like protein GARS_A PF01071.14 EJS43859.1 - 4.8e-81 270.9 0.0 7.7e-81 270.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EJS43859.1 - 4.7e-32 110.4 0.1 5e-31 107.1 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EJS43859.1 - 1.4e-30 106.3 0.0 2.9e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EJS43859.1 - 2.9e-26 91.4 0.2 6.8e-26 90.2 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EJS43859.1 - 3.4e-15 56.0 1.4 3.4e-15 56.0 0.9 2.4 3 0 0 3 3 2 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 EJS43859.1 - 1.8e-06 26.9 0.0 3.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EJS43859.1 - 3.8e-06 26.7 0.0 8.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.5 EJS43859.1 - 0.0057 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EJS43859.1 - 0.0087 15.9 0.2 0.035 13.9 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EJS43859.1 - 0.0097 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.1 EJS43859.1 - 0.039 13.0 0.1 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Sec15 PF04091.7 EJS43860.1 - 1.3e-108 363.0 7.6 1.3e-108 363.0 5.2 2.3 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like SPRY PF00622.23 EJS43863.1 - 9.1e-28 96.8 0.1 1.8e-27 95.9 0.1 1.5 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EJS43863.1 - 1.9e-13 50.3 3.1 4.2e-13 49.2 1.8 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EJS43863.1 - 0.0016 18.1 0.2 0.006 16.3 0.0 2.1 2 0 0 2 2 2 1 LisH Ribosomal_L29e PF01779.12 EJS43864.1 - 1.8e-24 85.2 8.8 2.4e-24 84.8 6.1 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family UCR_hinge PF02320.11 EJS43865.1 - 3.1e-20 71.8 2.6 5.8e-20 71.0 1.8 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF506 PF04720.7 EJS43865.1 - 0.0019 17.8 6.3 0.0022 17.6 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF506) RAB3GAP2_C PF14656.1 EJS43865.1 - 0.032 12.3 1.7 0.031 12.4 1.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Sigma70_ner PF04546.8 EJS43865.1 - 0.038 13.5 25.0 0.04 13.5 16.9 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 EJS43865.1 - 0.062 11.2 25.3 0.065 11.1 17.5 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 EJS43865.1 - 0.083 10.9 14.6 0.087 10.9 10.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 EJS43865.1 - 0.14 10.2 15.6 0.14 10.1 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.7 EJS43865.1 - 0.24 10.1 2.5 0.29 9.8 1.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Daxx PF03344.10 EJS43865.1 - 0.28 9.6 26.1 0.33 9.3 18.1 1.0 1 0 0 1 1 1 0 Daxx Family Rep_4 PF05797.6 EJS43865.1 - 0.43 9.2 8.1 0.5 9.0 5.6 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Vfa1 PF08432.5 EJS43865.1 - 0.48 10.4 12.8 0.6 10.1 8.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CENP-T PF15511.1 EJS43865.1 - 0.85 8.7 18.3 1 8.5 12.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T FLO_LFY PF01698.11 EJS43865.1 - 1.5 7.6 10.5 1.9 7.2 7.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Pro_CA PF00484.14 EJS43865.1 - 1.9 8.4 4.3 1.8 8.5 2.4 1.4 1 1 0 1 1 1 0 Carbonic anhydrase Hid1 PF12722.2 EJS43865.1 - 2.5 5.6 4.8 2.8 5.5 3.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2722 PF10846.3 EJS43865.1 - 2.9 6.8 7.8 3 6.7 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Mpp10 PF04006.7 EJS43865.1 - 2.9 6.1 25.5 3.3 5.9 17.7 1.0 1 0 0 1 1 1 0 Mpp10 protein TLP-20 PF06088.6 EJS43865.1 - 3.3 7.3 8.0 4.8 6.8 5.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SDA1 PF05285.7 EJS43865.1 - 5.7 6.1 28.5 6.8 5.8 19.8 1.0 1 0 0 1 1 1 0 SDA1 YL1 PF05764.8 EJS43865.1 - 6.6 6.2 22.6 7.6 6.0 15.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF1510 PF07423.6 EJS43865.1 - 9.5 5.5 21.0 11 5.3 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HLH PF00010.21 EJS43866.1 - 4e-13 48.8 2.6 9e-13 47.7 0.4 2.6 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Pox_A11 PF05061.8 EJS43866.1 - 2.3 7.2 5.9 0.49 9.4 0.1 2.4 3 0 0 3 3 3 0 Poxvirus A11 Protein Mucin PF01456.12 EJS43866.1 - 6.5 6.5 23.3 1.6 8.4 1.0 2.5 3 0 0 3 3 3 0 Mucin-like glycoprotein APC_CDC26 PF10471.4 EJS43867.1 - 4.6e-11 43.3 9.5 1.6e-10 41.5 6.6 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 DUF2457 PF10446.4 EJS43867.1 - 0.087 11.5 21.5 0.1 11.3 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SPX PF03105.14 EJS43867.1 - 0.11 12.2 8.0 0.13 12.0 5.6 1.0 1 0 0 1 1 1 0 SPX domain NOA36 PF06524.7 EJS43867.1 - 0.26 10.4 13.7 0.32 10.1 9.5 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 EJS43867.1 - 0.29 10.8 12.1 0.4 10.3 8.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 EJS43867.1 - 0.43 9.0 9.3 0.5 8.8 6.5 1.0 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 EJS43867.1 - 0.43 10.8 9.9 0.69 10.1 6.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TLP-20 PF06088.6 EJS43867.1 - 0.5 10.0 9.3 0.4 10.3 5.8 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF3295 PF11702.3 EJS43867.1 - 0.65 8.9 12.2 0.76 8.6 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Nop14 PF04147.7 EJS43867.1 - 0.79 7.5 14.0 0.87 7.4 9.7 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 EJS43867.1 - 1.2 8.9 7.6 1.5 8.6 5.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.6 EJS43867.1 - 3.1 5.5 9.3 3.1 5.5 6.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 EJS43867.1 - 4.5 7.6 17.2 4.9 7.5 11.3 1.7 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIA PF03153.8 EJS43867.1 - 4.9 6.9 17.3 5.5 6.7 12.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.3 EJS43867.1 - 7 6.5 17.2 9.8 6.0 11.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SWIRM PF04433.12 EJS43868.1 - 1.9e-32 111.2 0.2 4.1e-32 110.1 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EJS43868.1 - 1.4e-17 62.9 4.1 2.3e-17 62.2 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EJS43868.1 - 5.8e-07 29.4 0.1 1.1e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EJS43868.1 - 1.7e-06 28.0 0.3 1.1e-05 25.4 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain Elf1 PF05129.8 EJS43868.1 - 0.0075 15.9 1.4 0.012 15.2 0.3 1.8 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like SNF2_N PF00176.18 EJS43869.1 - 1.2e-71 240.9 0.4 2.3e-71 240.0 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EJS43869.1 - 2.3e-15 56.1 0.0 1e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EJS43869.1 - 4e-07 29.6 0.0 9.6e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ING PF12998.2 EJS43870.1 - 0.18 12.1 0.1 0.18 12.1 0.1 3.1 1 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding SAPS PF04499.10 EJS43871.1 - 7.2e-172 572.2 11.7 7.2e-172 572.2 8.1 4.0 4 0 0 4 4 4 2 SIT4 phosphatase-associated protein DnaJ PF00226.26 EJS43872.1 - 2.7e-13 49.4 3.2 2.7e-13 49.4 2.2 1.9 2 0 0 2 2 2 1 DnaJ domain DUF1512 PF07431.7 EJS43872.1 - 0.026 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) RNA_pol_Rbc25 PF08292.7 EJS43872.1 - 0.059 13.5 0.4 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Thioredox_DsbH PF03190.10 EJS43873.1 - 0.014 15.1 0.1 0.019 14.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Peptidase_M20 PF01546.23 EJS43874.1 - 6.3e-30 104.0 0.0 9.4e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EJS43874.1 - 3.3e-11 42.9 0.0 5e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF848 PF05852.6 EJS43874.1 - 0.081 12.7 0.0 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Mito_carr PF00153.22 EJS43875.1 - 4.7e-38 128.7 6.6 9.6e-19 66.8 0.4 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein QRPTase_C PF01729.14 EJS43877.1 - 1.2e-59 200.6 0.0 1.5e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EJS43877.1 - 7e-24 83.4 0.0 1.7e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF155 PF02582.9 EJS43878.1 - 5.9e-59 198.8 0.2 1.1e-58 197.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2638 PF10937.3 EJS43879.1 - 1.8e-34 119.0 0.2 2.1e-34 118.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Proteasome PF00227.21 EJS43880.1 - 3.6e-24 85.0 0.0 4.8e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Adap_comp_sub PF00928.16 EJS43881.1 - 1.9e-09 37.0 0.1 2.9e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EJS43881.1 - 8.4e-09 35.2 2.9 1.7e-08 34.2 2.0 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CDC37_N PF03234.9 EJS43881.1 - 0.0052 17.1 3.8 0.057 13.7 0.1 2.4 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding muHD PF10291.4 EJS43881.1 - 0.027 13.6 0.1 0.1 11.7 0.0 1.8 1 1 0 1 1 1 0 Muniscin C-terminal mu homology domain SAC3_GANP PF03399.11 EJS43882.1 - 2e-31 109.1 2.4 2.7e-31 108.7 1.6 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EJS43882.1 - 2.8e-20 72.5 2.4 5.5e-20 71.6 1.6 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Hexokinase_2 PF03727.11 EJS43883.1 - 6.4e-98 326.8 0.0 1.2e-97 325.8 0.0 1.4 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.16 EJS43883.1 - 5.5e-88 293.6 0.1 1.9e-87 291.9 0.1 1.7 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.16 EJS43883.1 - 0.0041 16.4 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Acetyltransf_13 PF13880.1 EJS43884.1 - 6.9e-20 70.5 0.0 1.6e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EJS43884.1 - 5.8e-10 38.5 0.3 9.4e-10 37.9 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EJS43884.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family DSPn PF14671.1 EJS43885.1 - 6.8e-50 168.7 0.0 2e-49 167.2 0.0 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EJS43885.1 - 1.4e-24 86.1 0.0 6.2e-24 84.0 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EJS43885.1 - 0.00028 20.2 0.7 0.00052 19.4 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EJS43885.1 - 0.00066 19.1 0.5 0.0016 17.9 0.1 1.8 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EJS43885.1 - 0.0055 16.7 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EJS43885.1 - 0.11 12.7 1.7 0.24 11.6 0.1 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family ORC6 PF05460.8 EJS43885.1 - 2.2 7.2 9.0 3.2 6.7 6.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) WD40 PF00400.27 EJS43886.1 - 0.066 13.1 0.3 20 5.2 0.0 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat zf-RING_UBOX PF13445.1 EJS43886.1 - 0.97 9.2 5.7 1.5 8.6 2.7 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Rtf2 PF04641.7 EJS43886.1 - 1.2 8.3 5.9 0.7 9.0 2.3 1.7 1 1 0 1 1 1 0 Rtf2 RING-finger FAD_binding_1 PF00667.15 EJS43887.1 - 1.2e-70 237.4 0.0 1.9e-70 236.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EJS43887.1 - 9.3e-10 39.0 0.0 4.5e-09 36.8 0.0 2.2 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EJS43887.1 - 0.092 12.8 0.0 0.5 10.5 0.0 2.2 3 0 0 3 3 3 0 Oxidoreductase FAD-binding domain SMC_N PF02463.14 EJS43888.1 - 3.4e-74 248.7 0.3 2.5e-72 242.6 0.2 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EJS43888.1 - 2.6e-25 88.7 0.3 1.9e-24 85.8 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EJS43888.1 - 3.9e-10 40.1 13.4 3.8e-06 27.0 0.2 4.7 3 1 1 4 4 4 2 AAA domain AAA_23 PF13476.1 EJS43888.1 - 7.8e-10 39.4 33.1 7.8e-10 39.4 23.0 6.6 2 2 3 5 5 5 1 AAA domain GAS PF13851.1 EJS43888.1 - 7e-06 25.3 24.8 0.00017 20.8 2.9 8.1 3 2 5 8 8 8 2 Growth-arrest specific micro-tubule binding AAA_29 PF13555.1 EJS43888.1 - 2.3e-05 23.8 0.1 5.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 EJS43888.1 - 0.0057 16.2 5.6 0.0057 16.2 3.9 7.3 2 2 4 6 6 6 1 IncA protein Reo_sigmaC PF04582.7 EJS43888.1 - 0.066 12.3 36.6 0.14 11.3 2.1 6.1 2 2 4 7 7 7 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EJS43888.1 - 0.49 10.6 0.0 0.49 10.6 0.0 6.1 4 2 0 4 4 4 0 ABC transporter Glycogen_syn PF05693.8 EJS43889.1 - 0 1145.1 0.0 0 1144.9 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EJS43889.1 - 3e-10 39.7 0.0 2.3e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EJS43889.1 - 0.00012 21.7 0.1 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EJS43889.1 - 0.00059 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Pkinase PF00069.20 EJS43890.1 - 7.5e-72 241.5 0.0 1.2e-71 240.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43890.1 - 5.1e-38 130.6 0.0 7.3e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS43890.1 - 0.0042 16.0 0.0 0.31 9.9 0.0 2.5 2 1 0 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.4 EJS43890.1 - 0.008 15.5 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EJS43890.1 - 0.04 12.9 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1690 PF07956.6 EJS43891.1 - 7.3e-56 188.0 13.1 8.7e-56 187.8 9.1 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) XhlA PF10779.4 EJS43891.1 - 3.8 7.4 6.5 10 6.1 1.2 2.5 1 1 1 2 2 2 0 Haemolysin XhlA FlxA PF14282.1 EJS43891.1 - 9.8 6.1 17.2 8.5 6.3 4.0 2.4 1 1 0 2 2 2 0 FlxA-like protein UCH PF00443.24 EJS43892.1 - 3.1e-52 177.3 6.5 3.9e-52 176.9 4.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EJS43892.1 - 1.7e-17 63.7 14.1 3.1e-17 62.9 9.8 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EJS43892.1 - 0.00046 19.5 0.1 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family DUF1700 PF08006.6 EJS43892.1 - 0.047 12.9 0.1 0.17 11.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) ABC_tran PF00005.22 EJS43893.1 - 2.6e-47 160.5 1.5 4.8e-23 81.9 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EJS43893.1 - 2.6e-18 65.6 8.9 2.6e-18 65.6 6.2 2.7 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.1 EJS43893.1 - 9.1e-18 65.2 12.5 2.2e-06 27.8 0.0 5.1 3 2 2 5 5 5 3 AAA domain SMC_N PF02463.14 EJS43893.1 - 1.3e-10 40.8 0.0 0.0013 18.0 0.0 3.6 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EJS43893.1 - 9.6e-09 36.1 1.3 0.00054 20.7 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.1 EJS43893.1 - 2.7e-07 30.7 0.6 0.031 14.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EJS43893.1 - 7.9e-07 29.2 0.4 0.081 13.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EJS43893.1 - 1.5e-06 27.6 0.0 0.068 12.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 EJS43893.1 - 1.6e-06 27.8 0.0 0.013 15.1 0.0 2.7 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 EJS43893.1 - 4.7e-06 25.8 0.0 0.036 13.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EJS43893.1 - 5.5e-06 26.8 0.4 0.17 12.3 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_16 PF13191.1 EJS43893.1 - 7.8e-06 25.9 0.2 0.079 12.9 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.1 EJS43893.1 - 1.4e-05 25.0 0.0 0.071 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EJS43893.1 - 1.5e-05 24.9 0.1 0.19 11.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EJS43893.1 - 3.5e-05 23.0 20.7 0.048 12.7 0.0 5.8 3 1 2 6 6 6 2 AAA ATPase domain MobB PF03205.9 EJS43893.1 - 3.5e-05 23.5 0.0 0.19 11.3 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EJS43893.1 - 5.3e-05 23.4 0.3 0.16 12.1 0.0 3.5 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EJS43893.1 - 5.5e-05 23.1 0.0 0.11 12.4 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EJS43893.1 - 5.7e-05 22.7 0.0 0.022 14.2 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EJS43893.1 - 6.5e-05 23.2 13.2 0.14 12.5 0.0 5.1 5 2 1 6 6 5 2 AAA domain PduV-EutP PF10662.4 EJS43893.1 - 0.00011 21.7 0.6 0.18 11.3 0.0 2.9 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 EJS43893.1 - 0.00016 21.5 0.1 0.91 9.4 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EJS43893.1 - 0.00043 20.4 0.4 0.65 10.1 0.0 3.2 3 0 0 3 3 2 1 RNA helicase NTPase_1 PF03266.10 EJS43893.1 - 0.00048 19.8 0.0 0.29 10.8 0.0 2.6 2 0 0 2 2 2 1 NTPase NB-ARC PF00931.17 EJS43893.1 - 0.00087 18.2 0.0 1.1 8.0 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_10 PF12846.2 EJS43893.1 - 0.0011 18.5 0.2 2.5 7.4 0.0 3.4 3 1 0 3 3 3 1 AAA-like domain ArgK PF03308.11 EJS43893.1 - 0.0014 17.5 0.0 0.17 10.6 0.0 2.7 2 0 0 2 2 2 1 ArgK protein AAA_5 PF07728.9 EJS43893.1 - 0.0015 18.2 0.8 3.4 7.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EJS43893.1 - 0.0051 16.2 0.0 4 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EJS43893.1 - 0.0066 16.1 5.7 0.53 9.9 0.0 3.2 4 0 0 4 4 2 2 Archaeal ATPase Pox_A32 PF04665.7 EJS43893.1 - 0.0075 15.5 0.0 0.18 11.0 0.0 2.6 2 0 0 2 2 2 1 Poxvirus A32 protein Dynamin_N PF00350.18 EJS43893.1 - 0.01 15.6 5.3 0.15 11.8 0.0 3.7 4 1 0 4 4 4 0 Dynamin family AAA_23 PF13476.1 EJS43893.1 - 0.02 15.2 0.0 0.31 11.3 0.0 5.3 4 1 0 5 5 4 0 AAA domain FeoB_N PF02421.13 EJS43893.1 - 0.021 14.1 0.0 5.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.14 EJS43893.1 - 0.021 14.2 0.1 2.7 7.3 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 EJS43893.1 - 0.022 13.6 0.0 0.39 9.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein SRP54 PF00448.17 EJS43893.1 - 0.026 13.9 0.0 2.4 7.5 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 EJS43893.1 - 0.049 13.1 0.2 6.8 6.1 0.0 2.9 2 1 1 3 3 3 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 EJS43893.1 - 0.066 12.7 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 EJS43893.1 - 6.8 6.4 21.0 5.4 6.7 0.0 5.0 4 1 1 5 5 5 0 Domain of unknown function DUF87 PIP5K PF01504.13 EJS43894.1 - 1.1e-64 217.9 2.6 1.1e-64 217.9 1.8 3.0 4 0 0 4 4 4 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EJS43894.1 - 8.5e-24 84.0 0.1 2.5e-23 82.5 0.1 1.7 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EJS43894.1 - 1.1e-16 60.5 10.2 3.1e-16 58.9 7.1 1.9 1 0 0 1 1 1 1 FYVE zinc finger WD40 PF00400.27 EJS43895.1 - 4.4e-09 35.8 0.0 0.0019 17.9 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat CNH PF00780.17 EJS43895.1 - 0.0042 16.5 0.1 0.049 13.0 0.0 2.3 2 1 0 2 2 2 1 CNH domain Arrestin_C PF02752.17 EJS43896.1 - 2.8e-22 79.2 0.4 9e-22 77.6 0.1 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EJS43896.1 - 2.3e-11 43.7 0.0 1.6e-10 40.9 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EJS43896.1 - 0.00092 18.7 0.1 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like RRM_1 PF00076.17 EJS43897.1 - 5.1e-51 170.2 10.6 1.5e-20 72.6 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS43897.1 - 7e-33 112.4 0.8 7.7e-10 38.6 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS43897.1 - 2.4e-24 84.9 4.3 8.2e-08 31.9 0.2 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EJS43897.1 - 2.1e-05 24.1 2.0 0.45 10.3 0.0 4.9 3 2 1 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.1 EJS43897.1 - 8.6e-05 22.2 0.8 0.0046 16.7 0.0 3.5 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 EJS43897.1 - 0.022 14.3 0.6 0.45 10.0 0.0 2.7 3 0 0 3 3 3 0 Calcipressin NDK PF00334.14 EJS43897.1 - 0.035 13.8 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 Nucleoside diphosphate kinase PHP PF02811.14 EJS43898.1 - 7.9e-27 94.1 0.1 1.2e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 PHP domain VTC PF09359.5 EJS43899.1 - 1.3e-98 329.4 0.4 1.3e-98 329.4 0.3 1.8 3 0 0 3 3 3 1 VTC domain SPX PF03105.14 EJS43899.1 - 3.8e-22 79.3 23.7 1e-13 51.7 4.9 4.5 3 1 1 4 4 4 2 SPX domain DUF202 PF02656.10 EJS43899.1 - 2.9e-10 40.2 1.3 6.5e-10 39.0 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MBOAT PF03062.14 EJS43899.1 - 0.00042 19.5 0.2 0.00069 18.8 0.2 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family HN PF00423.14 EJS43899.1 - 0.08 11.2 0.1 0.59 8.3 0.0 2.2 2 0 0 2 2 2 0 Haemagglutinin-neuraminidase DUF4149 PF13664.1 EJS43899.1 - 1.5 8.9 4.6 7.7 6.6 3.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DEAD PF00270.24 EJS43900.1 - 5.5e-40 136.6 0.1 5.3e-39 133.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS43900.1 - 1.3e-20 73.0 0.0 3.3e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EJS43900.1 - 3.1e-18 65.0 0.1 6.7e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EJS43900.1 - 0.031 14.1 3.0 0.069 12.9 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Nic96 PF04097.9 EJS43901.1 - 8.3e-213 707.9 8.5 1.3e-212 707.3 5.9 1.3 1 0 0 1 1 1 1 Nup93/Nic96 HHH_4 PF14490.1 EJS43901.1 - 0.00068 19.3 0.4 0.095 12.4 0.0 3.1 3 0 0 3 3 3 2 Helix-hairpin-helix containing domain JAB PF01398.16 EJS43902.1 - 7.6e-34 115.8 0.2 7.6e-34 115.8 0.1 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EJS43902.1 - 1.6e-25 89.4 5.5 4.4e-25 88.0 3.8 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EJS43902.1 - 1.3e-08 34.3 0.0 2.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EJS43902.1 - 0.045 13.2 1.1 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) zf-UBP PF02148.14 EJS43903.1 - 1.1e-07 31.8 1.5 2.9e-07 30.4 1.0 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.24 EJS43903.1 - 8.6e-07 28.3 3.6 1.5e-05 24.3 2.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M24 PF00557.19 EJS43904.1 - 5.6e-60 202.4 0.0 7.4e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EJS43904.1 - 3.6e-27 94.3 0.0 1.1e-26 92.8 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain AAA_18 PF13238.1 EJS43905.1 - 2.5e-06 27.8 0.1 9.9e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EJS43905.1 - 6.1e-06 27.0 0.0 3.3e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EJS43905.1 - 7.9e-06 25.9 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EJS43905.1 - 1.7e-05 24.7 0.0 0.0017 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EJS43905.1 - 5.8e-05 22.8 0.0 0.00033 20.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EJS43905.1 - 0.00013 21.1 0.0 0.00058 19.0 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin 6PF2K PF01591.13 EJS43905.1 - 0.00051 19.1 0.0 0.0008 18.5 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase PRK PF00485.13 EJS43905.1 - 0.00076 19.0 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 EJS43905.1 - 0.00087 19.2 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase KTI12 PF08433.5 EJS43905.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 EJS43905.1 - 0.0015 18.6 0.0 0.007 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EJS43905.1 - 0.0024 17.5 0.0 0.0065 16.1 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EJS43905.1 - 0.0029 17.7 0.0 0.0077 16.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EJS43905.1 - 0.0063 16.6 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 EJS43905.1 - 0.007 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ArgK PF03308.11 EJS43905.1 - 0.025 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 ArgK protein ABC_tran PF00005.22 EJS43905.1 - 0.027 14.7 0.2 0.05 13.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter T2SE PF00437.15 EJS43905.1 - 0.027 13.3 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 EJS43905.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EJS43905.1 - 0.033 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EJS43905.1 - 0.048 12.5 0.0 0.095 11.5 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.1 EJS43905.1 - 0.059 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EJS43905.1 - 0.075 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EJS43905.1 - 0.078 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EJS43905.1 - 0.079 12.6 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 1 0 NTPase TrwB_AAD_bind PF10412.4 EJS43905.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 EJS43905.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain FAM195 PF14799.1 EJS43906.1 - 0.21 11.4 6.9 2.9 7.7 2.5 2.4 2 1 0 2 2 2 0 FAM195 family Lin-8 PF03353.10 EJS43906.1 - 2.2 7.4 15.5 0.68 9.1 1.7 2.1 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist SIR2 PF02146.12 EJS43906.1 - 5.2 6.7 5.9 5.9 6.5 2.7 1.9 2 0 0 2 2 2 0 Sir2 family Pyr_redox_dim PF02852.17 EJS43907.1 - 1.1e-43 147.6 0.6 3e-43 146.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EJS43907.1 - 6.4e-38 130.6 13.3 6.3e-36 124.1 9.2 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EJS43907.1 - 1.7e-21 76.3 9.0 1.6e-18 66.9 0.6 3.7 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EJS43907.1 - 4.7e-12 45.7 4.3 2e-10 40.3 0.1 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EJS43907.1 - 2.4e-11 43.5 1.0 1.1e-05 25.3 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EJS43907.1 - 5.2e-10 38.7 9.7 6.1e-10 38.5 1.8 2.6 2 2 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EJS43907.1 - 1.2e-09 38.5 1.3 2.2e-06 27.8 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EJS43907.1 - 1.3e-08 34.1 0.1 1.3e-08 34.1 0.1 2.7 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.19 EJS43907.1 - 7.4e-07 28.3 14.6 0.00043 19.3 0.5 4.2 2 2 2 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EJS43907.1 - 8.2e-07 28.3 6.9 0.0011 18.0 0.2 3.3 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EJS43907.1 - 2.8e-06 26.0 15.1 2.5e-05 22.9 0.6 4.5 4 1 1 5 5 5 2 HI0933-like protein Thi4 PF01946.12 EJS43907.1 - 3.6e-06 26.2 0.4 0.00032 19.8 0.0 2.4 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 EJS43907.1 - 7.1e-05 22.4 1.2 0.28 10.7 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 EJS43907.1 - 0.00023 20.1 1.4 0.9 8.3 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) XdhC_C PF13478.1 EJS43907.1 - 0.0023 18.2 0.1 2.4 8.4 0.0 2.5 2 0 0 2 2 2 2 XdhC Rossmann domain 3HCDH_N PF02737.13 EJS43907.1 - 0.0035 17.0 4.5 0.011 15.4 0.3 2.8 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EJS43907.1 - 0.014 14.4 1.2 0.034 13.2 0.2 2.2 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EJS43907.1 - 0.029 14.6 1.4 1.5 9.1 0.2 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EJS43907.1 - 0.074 11.9 4.0 0.13 11.1 0.3 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EJS43907.1 - 0.078 12.3 6.1 0.22 10.8 1.0 2.6 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PTS_IIB PF02302.12 EJS43907.1 - 0.16 12.4 3.0 7.3 7.1 0.3 3.1 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit Trp_halogenase PF04820.9 EJS43907.1 - 0.28 9.7 5.9 0.095 11.3 0.2 2.3 3 0 0 3 3 3 0 Tryptophan halogenase LSM PF01423.17 EJS43908.1 - 5e-15 54.7 0.1 5.6e-15 54.6 0.1 1.0 1 0 0 1 1 1 1 LSM domain Acetyltransf_1 PF00583.19 EJS43909.1 - 2.5e-16 59.4 0.0 3.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EJS43909.1 - 6.4e-10 39.0 0.1 1e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EJS43909.1 - 4.7e-07 29.9 0.0 6.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EJS43909.1 - 0.00023 21.0 0.0 0.0006 19.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EJS43909.1 - 0.0019 18.3 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EJS43909.1 - 0.0039 17.1 0.2 0.0064 16.4 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DnaJ PF00226.26 EJS43910.1 - 3.6e-24 84.2 5.6 7.3e-24 83.2 3.9 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EJS43910.1 - 1.1e-23 82.9 2.4 1.2e-18 66.8 0.2 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EJS43910.1 - 5.8e-11 42.2 20.3 1e-10 41.4 14.1 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EJS43910.1 - 0.0025 17.4 6.7 0.029 14.0 1.1 2.4 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrome_C7 PF14522.1 EJS43910.1 - 0.014 14.9 9.4 0.042 13.4 6.5 1.9 1 0 0 1 1 1 0 Cytochrome c7 DUF2318 PF10080.4 EJS43910.1 - 3.3 7.5 7.0 2.9 7.7 2.3 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Antiterm PF03589.8 EJS43910.1 - 7.2 6.7 7.1 1.3e+02 2.7 3.2 3.4 1 1 2 3 3 3 0 Antitermination protein HSP9_HSP12 PF04119.7 EJS43911.1 - 2.3e-27 94.8 4.1 2.8e-27 94.5 1.0 2.2 2 1 1 3 3 3 1 Heat shock protein 9/12 DUF883 PF05957.8 EJS43911.1 - 0.059 13.7 1.1 0.21 11.9 0.7 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF357 PF04010.8 EJS43911.1 - 0.13 11.9 0.2 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF2585 PF10755.4 EJS43912.1 - 0.06 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) Sugar_tr PF00083.19 EJS43913.1 - 1.8e-166 554.1 35.7 2.1e-166 553.9 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS43913.1 - 1.3e-37 129.3 45.2 1.4e-30 106.2 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EJS43913.1 - 0.00024 19.6 12.2 0.00024 19.6 8.4 3.6 2 2 1 3 3 3 2 MFS/sugar transport protein Cytochrom_B_N PF00033.14 EJS43913.1 - 0.0016 17.8 5.6 0.0025 17.1 0.0 3.3 4 1 0 4 4 4 1 Cytochrome b(N-terminal)/b6/petB PDR_CDR PF06422.7 EJS43913.1 - 1.8 8.2 0.0 1.8 8.2 0.0 3.6 2 1 0 3 3 3 0 CDR ABC transporter WW PF00397.21 EJS43914.1 - 1.3e-07 31.3 2.1 1.3e-07 31.3 1.5 2.0 2 0 0 2 2 2 1 WW domain Suf PF05843.9 EJS43914.1 - 1.9 8.1 8.1 2.3 7.8 5.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 EJS43914.1 - 8.8 5.6 25.6 11 5.3 17.7 1.1 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 EJS43915.1 - 6.3e-45 149.5 23.0 8.3e-10 38.1 0.6 8.1 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.2 EJS43915.1 - 2.8e-08 33.3 0.2 5.7e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EJS43915.1 - 0.0015 18.1 0.3 0.0015 18.1 0.2 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EJS43915.1 - 0.018 13.2 8.6 0.77 7.8 0.4 4.5 2 1 1 4 4 4 0 Nucleoporin Nup120/160 tRNA-synt_2d PF01409.15 EJS43916.1 - 2.3e-90 302.1 0.0 2.9e-90 301.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EJS43916.1 - 1.9e-06 26.8 3.1 0.00021 20.1 0.1 3.3 2 2 1 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EJS43916.1 - 6e-06 25.9 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 EJS43916.1 - 0.0045 16.0 0.1 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 Histidyl-tRNA synthetase SRP1_TIP1 PF00660.12 EJS43917.1 - 7.5e-32 109.2 0.2 9.5e-32 108.9 0.1 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family CRC_subunit PF08624.5 EJS43918.1 - 2e-36 124.9 0.9 4.2e-36 123.9 0.6 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF1640 PF07798.6 EJS43919.1 - 9.5e-63 211.4 8.4 1.1e-62 211.2 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3584 PF12128.3 EJS43919.1 - 0.0017 15.8 8.0 0.0021 15.5 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) FlaC_arch PF05377.6 EJS43919.1 - 0.004 17.0 3.6 0.24 11.3 0.1 2.6 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Peptidase_M3 PF01432.15 EJS43919.1 - 0.042 12.8 1.2 0.054 12.5 0.8 1.1 1 0 0 1 1 1 0 Peptidase family M3 Nbl1_Borealin_N PF10444.4 EJS43919.1 - 0.065 12.6 1.2 0.3 10.4 0.1 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal YoaP PF14268.1 EJS43919.1 - 0.086 12.0 0.0 0.23 10.7 0.0 1.7 1 0 0 1 1 1 0 YoaP-like ApoLp-III PF07464.6 EJS43919.1 - 0.086 12.8 4.7 0.27 11.2 3.0 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF2407_C PF13373.1 EJS43919.1 - 0.17 11.8 1.4 0.42 10.5 1.0 1.7 1 1 0 1 1 1 0 DUF2407 C-terminal domain TBPIP PF07106.8 EJS43919.1 - 0.21 11.1 10.6 0.42 10.1 7.3 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 EJS43919.1 - 0.23 11.2 6.6 1.1 9.0 1.8 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.13 EJS43919.1 - 0.25 11.1 2.8 0.66 9.7 0.5 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper YjfB_motility PF14070.1 EJS43919.1 - 0.29 10.9 2.5 13 5.6 0.6 2.3 2 0 0 2 2 2 0 Putative motility protein DUF3410 PF11890.3 EJS43919.1 - 0.3 10.7 3.2 0.64 9.7 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3410) DUF1732 PF08340.6 EJS43919.1 - 0.51 10.1 7.6 0.5 10.2 4.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) Lzipper-MIP1 PF14389.1 EJS43919.1 - 0.58 10.3 4.7 4.3 7.5 3.2 2.2 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF342 PF03961.8 EJS43919.1 - 0.59 8.4 6.8 0.71 8.2 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 EJS43919.1 - 0.67 9.7 7.3 5.6 6.7 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.7 EJS43919.1 - 0.76 9.2 7.0 0.16 11.5 0.6 2.2 1 1 0 2 2 2 0 Bacteriophage Mu Gam like protein YlqD PF11068.3 EJS43919.1 - 0.79 9.7 12.0 1 9.4 3.1 2.3 1 1 1 2 2 2 0 YlqD protein Phage_lysis PF03245.8 EJS43919.1 - 0.93 9.4 6.2 0.92 9.5 0.2 2.3 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein FTA4 PF13093.1 EJS43919.1 - 1 8.7 8.3 1.6 8.1 5.7 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Syntaxin PF00804.20 EJS43919.1 - 1.5 9.0 12.3 4.6 7.4 5.0 2.3 1 1 1 2 2 2 0 Syntaxin Atg14 PF10186.4 EJS43919.1 - 3.9 6.3 8.1 0.55 9.1 2.4 1.7 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tup_N PF08581.5 EJS43919.1 - 4.4 7.5 10.9 4.6 7.5 0.3 2.8 3 0 0 3 3 3 0 Tup N-terminal TPR_MLP1_2 PF07926.7 EJS43919.1 - 6.5 6.5 12.0 60 3.3 8.3 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PMM PF03332.8 EJS43920.1 - 1.1e-114 381.5 0.3 1.2e-114 381.3 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EJS43920.1 - 1.7e-05 24.5 0.0 0.00044 19.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EJS43920.1 - 0.0038 16.3 0.0 0.0051 15.9 0.0 1.1 1 0 0 1 1 1 1 TMPIT-like protein Chordopox_A13L PF05961.6 EJS43920.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein OTU PF02338.14 EJS43921.1 - 7.4e-14 52.3 0.0 1.3e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EJS43921.1 - 0.00017 21.0 0.4 0.00045 19.6 0.1 1.9 2 1 0 2 2 2 1 Peptidase C65 Otubain DUF764 PF05561.6 EJS43921.1 - 0.034 13.5 0.3 0.054 12.9 0.2 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) ThiS PF02597.15 EJS43921.1 - 0.13 12.7 0.1 0.49 10.8 0.0 2.0 2 0 0 2 2 2 0 ThiS family Sugar_tr PF00083.19 EJS43922.1 - 2.1e-58 197.9 27.1 2.7e-58 197.6 18.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS43922.1 - 2.2e-14 52.9 34.4 1.3e-12 47.1 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ras PF00071.17 EJS43923.1 - 2e-64 215.8 0.5 2.4e-64 215.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS43923.1 - 4.9e-20 72.1 0.4 9e-20 71.3 0.1 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EJS43923.1 - 5.1e-17 61.6 0.4 6.9e-17 61.2 0.2 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EJS43923.1 - 9.8e-07 28.1 0.3 1.4e-06 27.6 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EJS43923.1 - 9.4e-06 25.1 0.2 2e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EJS43923.1 - 4.7e-05 23.3 0.3 7.2e-05 22.7 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EJS43923.1 - 0.0022 17.2 0.9 0.0023 17.1 0.1 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EJS43923.1 - 0.008 16.3 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain YTH PF04146.10 EJS43923.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 1 0 1 1 1 0 YT521-B-like domain LANC_like PF05147.8 EJS43923.1 - 0.017 13.7 0.7 0.24 9.9 0.1 2.0 1 1 1 2 2 2 0 Lanthionine synthetase C-like protein DUF258 PF03193.11 EJS43923.1 - 0.017 14.3 0.0 0.036 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 EJS43923.1 - 0.029 13.4 0.2 0.12 11.3 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_5 PF07728.9 EJS43923.1 - 0.044 13.5 0.1 0.097 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EJS43923.1 - 0.052 13.0 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EJS43923.1 - 0.057 13.3 0.2 0.16 11.9 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EJS43923.1 - 0.06 13.6 1.0 0.24 11.7 0.7 2.0 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 EJS43923.1 - 0.077 13.1 0.1 0.63 10.2 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EJS43923.1 - 0.084 12.1 0.2 0.44 9.8 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Tubulin PF00091.20 EJS43924.1 - 8.8e-71 238.1 0.0 1.6e-70 237.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EJS43924.1 - 5.8e-48 162.1 0.1 1.3e-47 160.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EJS43924.1 - 0.0026 17.2 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EJS43924.1 - 0.012 15.7 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain RNA_pol PF00940.14 EJS43925.1 - 6.5e-161 535.3 0.0 1.1e-160 534.6 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EJS43925.1 - 8.2e-90 301.2 0.3 1.6e-89 300.3 0.2 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DUF726 PF05277.7 EJS43926.1 - 6.4e-139 462.6 1.8 1e-138 461.9 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Aminotran_5 PF00266.14 EJS43927.1 - 5.8e-22 77.9 0.0 7.6e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Pkinase PF00069.20 EJS43928.1 - 7.1e-30 104.0 0.0 2.4e-26 92.4 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EJS43928.1 - 6.1e-14 51.7 0.0 8.4e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EJS43928.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EJS43928.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EJS43928.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.22 EJS43929.1 - 3e-17 63.2 0.0 7.3e-17 61.9 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EJS43929.1 - 1.9e-09 37.8 0.2 2.4e-08 34.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EJS43929.1 - 4.2e-05 22.8 0.0 0.13 11.4 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EJS43929.1 - 0.00012 21.2 0.0 0.084 11.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EJS43929.1 - 0.002 17.5 0.1 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EJS43929.1 - 0.0033 18.2 0.4 0.0074 17.0 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EJS43929.1 - 0.0036 16.8 0.1 0.0064 15.9 0.1 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_24 PF13479.1 EJS43929.1 - 0.0097 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 EJS43929.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Dynamin family DUF258 PF03193.11 EJS43929.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EJS43929.1 - 0.028 14.7 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EJS43929.1 - 0.043 13.5 1.6 15 5.2 0.0 3.1 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EJS43929.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EJS43929.1 - 0.095 13.0 0.3 0.22 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EJS43929.1 - 0.12 12.2 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EJS43929.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.5 1 1 0 1 1 1 0 ArgK protein DUF3584 PF12128.3 EJS43929.1 - 0.13 9.6 0.1 0.17 9.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SRP54 PF00448.17 EJS43929.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MutS_V PF00488.16 EJS43929.1 - 0.13 11.6 0.1 5.5 6.3 0.0 2.5 2 1 0 2 2 2 0 MutS domain V Zeta_toxin PF06414.7 EJS43929.1 - 0.16 11.0 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EJS43929.1 - 0.29 11.0 1.3 0.58 10.1 0.8 1.9 1 1 0 1 1 1 0 AAA ATPase domain RabGAP-TBC PF00566.13 EJS43930.1 - 1.9e-14 53.6 7.5 3.8e-14 52.6 5.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Mur_ligase_M PF08245.7 EJS43930.1 - 0.049 13.6 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Mur ligase middle domain STE2 PF02116.10 EJS43931.1 - 2.5e-104 348.3 23.6 2.9e-104 348.0 16.4 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF2976 PF11190.3 EJS43931.1 - 0.56 9.7 9.2 0.33 10.5 2.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) PGAP1 PF07819.8 EJS43932.1 - 3.8e-89 298.1 0.0 9.2e-89 296.8 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EJS43932.1 - 7.8e-05 22.6 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EJS43932.1 - 0.0029 17.2 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EJS43932.1 - 0.0054 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EJS43932.1 - 0.025 13.8 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AA_permease PF00324.16 EJS43933.1 - 1.4e-122 409.5 40.4 1.6e-122 409.3 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS43933.1 - 2.5e-32 111.9 43.8 3.9e-32 111.3 30.2 1.4 1 1 0 1 1 1 1 Amino acid permease Dak1 PF02733.12 EJS43934.1 - 5.1e-148 491.9 2.7 6.4e-148 491.6 1.8 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EJS43934.1 - 3.1e-43 147.4 2.9 7.1e-43 146.2 2.0 1.6 1 0 0 1 1 1 1 DAK2 domain Sugar_tr PF00083.19 EJS43935.1 - 9.2e-71 238.7 31.2 1.1e-70 238.4 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS43935.1 - 8.2e-24 83.9 37.1 3.9e-13 48.8 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF606 PF04657.8 EJS43935.1 - 0.00026 21.1 0.9 0.00026 21.1 0.6 3.7 3 1 0 3 3 3 1 Protein of unknown function, DUF606 BT1 PF03092.11 EJS43935.1 - 0.00072 18.3 7.2 0.0078 14.9 4.8 2.1 1 1 0 1 1 1 1 BT1 family MFS_2 PF13347.1 EJS43935.1 - 0.0012 17.3 29.1 0.053 11.9 7.6 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein REC114-like PF15165.1 EJS43935.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like JSRP PF15312.1 EJS43935.1 - 0.49 10.4 1.5 1.8 8.5 0.9 1.9 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein DUF2668 PF10873.3 EJS43935.1 - 3.4 7.7 10.5 1.9 8.6 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2668) 5-FTHF_cyc-lig PF01812.15 EJS43936.1 - 1.3e-52 178.2 0.0 1.7e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family RRM_1 PF00076.17 EJS43937.1 - 3.4e-86 282.9 5.2 1.8e-21 75.5 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS43937.1 - 9.5e-60 198.5 0.1 2.9e-15 55.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS43937.1 - 3.7e-42 141.9 0.1 7.9e-09 35.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EJS43937.1 - 7e-24 83.2 1.0 6.9e-23 80.1 0.0 2.8 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EJS43937.1 - 3.4e-07 30.0 4.7 0.0084 15.9 1.2 4.7 3 1 1 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.1 EJS43937.1 - 7.6e-05 22.4 0.3 0.73 9.6 0.0 3.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif YflT PF11181.3 EJS43937.1 - 0.0003 20.8 4.9 0.51 10.5 0.5 3.6 2 1 1 3 3 3 2 Heat induced stress protein YflT CbiG_mid PF11761.3 EJS43937.1 - 0.0021 18.2 0.1 0.51 10.6 0.0 2.9 2 1 0 2 2 2 1 Cobalamin biosynthesis central region OB_RNB PF08206.6 EJS43937.1 - 0.011 15.2 4.0 8 6.0 0.2 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 EJS43937.1 - 0.04 13.6 0.2 13 5.5 0.0 3.9 4 0 0 4 4 4 0 Limkain b1 TC1 PF15063.1 EJS43937.1 - 0.044 13.3 0.0 0.15 11.6 0.0 1.9 1 0 0 1 1 1 0 Thyroid cancer protein 1 CSD PF00313.17 EJS43937.1 - 0.27 11.0 2.6 13 5.6 0.0 3.4 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain PolyA_pol PF01743.15 EJS43939.1 - 6.2e-32 110.4 0.0 1.2e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EJS43939.1 - 1.4e-05 24.5 0.0 4.2e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EJS43939.1 - 0.0014 18.4 0.0 0.0055 16.5 0.0 2.0 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative DUF3958 PF13125.1 EJS43939.1 - 0.081 12.8 1.8 2.9 7.8 0.2 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3958) Chordopox_A13L PF05961.6 EJS43939.1 - 0.082 12.8 1.1 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 Chordopoxvirus A13L protein JmjC PF02373.17 EJS43940.1 - 8e-42 142.0 1.9 2.6e-41 140.4 0.5 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 EJS43940.1 - 9.7e-15 53.8 2.2 2.3e-14 52.5 1.5 1.7 1 0 0 1 1 1 1 jmjN domain zf-H2C2_2 PF13465.1 EJS43940.1 - 4.8e-08 32.9 15.7 3.5e-07 30.1 4.7 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EJS43940.1 - 2e-07 30.9 17.3 0.00089 19.4 2.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS43940.1 - 1.7e-06 27.9 13.0 0.0012 19.0 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EJS43940.1 - 0.0026 17.6 10.0 0.02 14.7 2.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EJS43940.1 - 1.1 9.2 6.4 6 6.9 4.4 2.2 1 1 0 1 1 1 0 Zinc ribbon domain zf-met PF12874.2 EJS43940.1 - 1.9 8.8 8.8 11 6.3 1.3 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EJS43940.1 - 2.6 8.2 16.1 0.55 10.4 3.4 3.4 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF1227 PF06777.6 EJS43941.1 - 1.2e-59 200.1 1.1 3e-59 198.9 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EJS43941.1 - 1.1e-52 178.0 5.1 2e-52 177.0 3.6 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EJS43941.1 - 1.7e-45 154.9 0.1 8.6e-45 152.6 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 EJS43941.1 - 0.0024 17.4 0.1 0.79 9.1 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase SNF2_N PF00176.18 EJS43941.1 - 0.016 14.0 0.2 0.65 8.7 0.0 2.3 2 0 0 2 2 2 0 SNF2 family N-terminal domain ResIII PF04851.10 EJS43941.1 - 0.055 13.2 0.7 0.93 9.2 0.5 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Sec63 PF02889.11 EJS43942.1 - 4e-169 561.7 5.0 4.7e-89 298.7 0.1 2.9 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 EJS43942.1 - 3.6e-51 173.0 0.1 3.8e-32 111.1 0.0 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EJS43942.1 - 1.5e-11 44.5 4.7 2e-08 34.2 0.0 4.3 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EJS43942.1 - 1.2e-07 31.4 0.0 7.2e-07 28.9 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EJS43942.1 - 6.3e-07 29.5 0.2 0.0066 16.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EJS43942.1 - 0.001 18.3 0.0 0.66 9.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 EJS43942.1 - 0.0018 18.0 0.0 1.2 8.9 0.0 2.9 3 0 0 3 3 3 2 Part of AAA domain FtsK_SpoIIIE PF01580.13 EJS43942.1 - 0.0029 17.0 0.0 0.019 14.4 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EJS43942.1 - 0.012 15.0 0.4 0.83 9.0 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain T2SE PF00437.15 EJS43942.1 - 0.022 13.6 0.0 4.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.1 EJS43942.1 - 0.05 13.5 0.0 0.75 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Rad17 PF03215.10 EJS43943.1 - 2.5e-162 541.2 10.9 1.9e-160 535.0 7.5 2.1 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 EJS43943.1 - 0.0004 19.6 0.0 0.0008 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EJS43943.1 - 0.0011 18.9 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EJS43943.1 - 0.0016 18.5 0.0 0.0058 16.7 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.1 EJS43943.1 - 0.0022 17.4 0.0 0.0054 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 EJS43943.1 - 0.0053 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EJS43943.1 - 0.029 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EJS43943.1 - 0.077 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glutaredoxin PF00462.19 EJS43944.1 - 1.1e-19 70.1 0.0 3e-17 62.3 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EJS43944.1 - 5e-16 58.2 0.0 1.1e-15 57.1 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.16 EJS43944.1 - 2.2e-05 24.1 0.1 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EJS43944.1 - 5.9e-05 23.1 0.3 0.00093 19.2 0.0 2.5 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EJS43944.1 - 0.00011 22.4 0.7 0.0021 18.2 0.1 2.8 2 2 0 2 2 2 1 Thioredoxin-like domain DIM1 PF02966.11 EJS43944.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_6 PF13848.1 EJS43944.1 - 0.0031 17.3 0.2 0.017 14.9 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EJS43944.1 - 0.0093 15.9 0.1 0.044 13.8 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 EJS43944.1 - 0.014 14.8 0.1 0.43 10.1 0.0 2.1 1 1 1 2 2 2 0 Redoxin DNA_processg_A PF02481.10 EJS43944.1 - 0.038 12.8 0.0 5.9 5.7 0.0 2.6 3 0 0 3 3 3 0 DNA recombination-mediator protein A TrbC_Ftype PF09673.5 EJS43944.1 - 0.046 13.3 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein SH3BGR PF04908.10 EJS43944.1 - 0.068 13.1 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein HyaE PF07449.6 EJS43944.1 - 0.075 12.9 0.1 0.92 9.4 0.0 2.6 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE ArsC PF03960.10 EJS43944.1 - 0.093 12.8 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 ArsC family Methyltransf_31 PF13847.1 EJS43945.1 - 1.1e-11 44.5 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EJS43945.1 - 8.7e-10 38.9 0.0 1.9e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EJS43945.1 - 1.4e-09 38.3 0.0 3.6e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EJS43945.1 - 2.3e-08 33.9 0.0 6.2e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS43945.1 - 6.7e-08 33.0 0.0 1.3e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EJS43945.1 - 4e-07 30.3 0.1 8.7e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EJS43945.1 - 0.0001 21.4 0.0 0.00021 20.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EJS43945.1 - 0.00014 21.0 0.0 0.00019 20.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EJS43945.1 - 0.00041 19.5 0.0 0.00083 18.5 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EJS43945.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EJS43945.1 - 0.0075 15.6 0.1 0.077 12.3 0.0 2.0 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 EJS43945.1 - 0.019 14.9 0.0 0.031 14.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EJS43945.1 - 0.056 12.8 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AAA_12 PF13087.1 EJS43946.1 - 1.9e-61 206.9 0.1 5.1e-61 205.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EJS43946.1 - 1.3e-41 142.7 0.5 1.3e-41 142.7 0.4 3.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EJS43946.1 - 1.1e-09 37.8 0.0 2.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EJS43946.1 - 3.8e-09 36.4 0.0 6.5e-08 32.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EJS43946.1 - 4.7e-07 29.5 1.1 0.011 15.2 0.0 3.9 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EJS43946.1 - 0.00076 19.5 0.0 0.0042 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.1 EJS43946.1 - 0.00084 19.4 0.1 0.0038 17.3 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 EJS43946.1 - 0.0054 15.9 0.0 0.038 13.2 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.24 EJS43946.1 - 0.0094 16.1 0.1 0.059 13.5 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EJS43946.1 - 0.035 14.2 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain 14-3-3 PF00244.15 EJS43947.1 - 7.5e-115 381.9 6.4 9.5e-115 381.6 4.4 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.6 EJS43947.1 - 0.049 13.4 1.0 0.17 11.7 0.7 1.9 1 0 0 1 1 1 0 Flagellar protein FlaF DUF885 PF05960.6 EJS43947.1 - 0.086 11.9 6.8 0.013 14.7 1.2 1.9 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF885) SPACA7 PF15307.1 EJS43947.1 - 0.73 9.9 5.4 2.6 8.2 0.1 3.2 2 1 1 3 3 3 0 Sperm acrosome-associated protein 7 E1_dh PF00676.15 EJS43948.1 - 5.2e-122 406.2 0.0 6.6e-122 405.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EJS43948.1 - 0.0023 16.8 0.0 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 EJS43948.1 - 0.011 16.3 3.8 0.066 13.8 0.1 3.1 2 2 0 2 2 2 0 KRTAP type 7 family PV_NSP1 PF12433.3 EJS43949.1 - 0.11 12.6 1.1 0.63 10.1 0.1 2.5 2 0 0 2 2 2 0 Parvovirus non-structural protein 1 SPT2 PF08243.6 EJS43950.1 - 9.2e-29 100.1 28.5 9.2e-29 100.1 19.7 2.4 3 0 0 3 3 3 1 SPT2 chromatin protein SNF2_N PF00176.18 EJS43951.1 - 4e-76 255.6 0.1 8.2e-76 254.6 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EJS43951.1 - 8.1e-31 106.2 0.7 8.1e-31 106.2 0.5 3.8 5 0 0 5 5 5 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EJS43951.1 - 2.2e-23 81.6 2.1 1.2e-14 53.7 0.1 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EJS43951.1 - 1.2e-15 57.0 0.0 2e-14 53.1 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Myb_DNA-bind_6 PF13921.1 EJS43951.1 - 3.1e-05 23.9 0.0 0.00016 21.7 0.0 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EJS43951.1 - 0.00073 19.5 0.0 0.003 17.5 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Aminotran_1_2 PF00155.16 EJS43952.1 - 4.2e-20 72.0 0.0 4.9e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EJS43952.1 - 3.3e-06 25.9 0.0 5.2e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase 60KD_IMP PF02096.15 EJS43953.1 - 2.2e-38 131.8 1.4 2.2e-38 131.8 0.9 2.1 2 0 0 2 2 2 1 60Kd inner membrane protein UPF0160 PF03690.8 EJS43954.1 - 2.5e-124 414.8 0.0 2.9e-124 414.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) GDI PF00996.13 EJS43956.1 - 2.2e-219 728.2 0.1 2.8e-219 727.8 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EJS43956.1 - 0.0071 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain eIF3g PF12353.3 EJS43957.1 - 0.12 12.2 1.9 0.14 12.0 0.3 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G DUF747 PF05346.6 EJS43958.1 - 1e-95 320.6 20.9 1.5e-95 320.1 14.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family COX15-CtaA PF02628.10 EJS43959.1 - 1.7e-99 332.5 7.1 2e-99 332.2 4.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Cytochrom_B561 PF03188.11 EJS43959.1 - 0.0035 17.1 2.4 0.0035 17.1 1.7 2.6 3 1 0 3 3 3 1 Eukaryotic cytochrome b561 HhH-GPD PF00730.20 EJS43960.1 - 5.1e-13 49.2 0.0 9.6e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Asp_protease PF09668.5 EJS43961.1 - 7.1e-51 170.9 0.2 1.1e-50 170.3 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.26 EJS43961.1 - 2.1e-09 36.9 0.0 1.1e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Asp_protease_2 PF13650.1 EJS43961.1 - 6.7e-09 36.1 0.3 1.5e-08 34.9 0.2 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EJS43961.1 - 1.7e-07 31.0 0.2 3.4e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EJS43961.1 - 1.7e-06 27.9 0.1 1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EJS43961.1 - 0.00053 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UN_NPL4 PF11543.3 EJS43961.1 - 0.0061 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 UBA_3 PF09288.5 EJS43961.1 - 0.1 12.2 0.0 0.9 9.1 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain UCH PF00443.24 EJS43962.1 - 2.1e-68 230.3 2.0 3.6e-68 229.6 1.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EJS43962.1 - 3e-28 99.1 1.7 5e-28 98.3 1.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EJS43962.1 - 1.1e-05 25.7 0.0 2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain FTR1 PF03239.9 EJS43963.1 - 7e-107 356.9 7.2 8.3e-107 356.6 5.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF839 PF05787.8 EJS43963.1 - 0.028 13.3 0.1 0.038 12.9 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) LSM PF01423.17 EJS43964.1 - 5.2e-18 64.3 0.5 6.1e-18 64.1 0.3 1.1 1 0 0 1 1 1 1 LSM domain TBP PF00352.16 EJS43965.1 - 1.9e-69 229.0 0.4 4.1e-35 119.0 0.0 2.4 3 0 0 3 3 3 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EJS43965.1 - 0.00014 21.8 0.1 0.62 10.1 0.0 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF3378) Myosin_tail_1 PF01576.14 EJS43966.1 - 0.0018 16.1 10.3 0.0018 16.1 7.2 2.1 2 1 0 2 2 2 1 Myosin tail NYD-SP28_assoc PF14775.1 EJS43966.1 - 0.0098 15.5 1.0 0.0098 15.5 0.7 2.3 2 0 0 2 2 2 1 Sperm tail C-terminal domain Reo_sigmaC PF04582.7 EJS43966.1 - 0.012 14.8 1.2 0.019 14.1 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Syntaxin-6_N PF09177.6 EJS43966.1 - 0.14 12.5 8.9 0.29 11.5 3.4 3.0 2 1 1 3 3 2 0 Syntaxin 6, N-terminal ADIP PF11559.3 EJS43966.1 - 0.21 11.4 13.3 0.15 11.9 4.9 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 EJS43966.1 - 0.76 9.6 14.0 0.072 12.9 5.9 2.0 2 0 0 2 2 2 0 Tropomyosin like Microtub_assoc PF07989.6 EJS43966.1 - 0.8 9.5 11.0 0.75 9.6 6.1 2.2 2 0 0 2 2 2 0 Microtubule associated Seryl_tRNA_N PF02403.17 EJS43966.1 - 1.3 9.0 8.5 0.18 11.8 2.3 2.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FliD_N PF02465.13 EJS43966.1 - 1.3 9.3 8.5 2.8 8.3 0.9 3.0 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus TBPIP PF07106.8 EJS43966.1 - 1.8 8.0 11.4 2.6 7.5 5.9 2.7 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EJS43966.1 - 2.6 7.7 16.3 1.9 8.2 6.9 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EJS43966.1 - 3.5 7.4 14.8 0.43 10.4 4.9 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EJS43966.1 - 4.6 6.7 16.1 5.6 6.5 7.0 2.8 2 1 0 2 2 2 0 IncA protein CENP-H PF05837.7 EJS43966.1 - 9.1 6.5 12.0 0.66 10.1 0.6 3.7 3 1 0 3 3 3 0 Centromere protein H (CENP-H) Flocculin_t3 PF13928.1 EJS43967.1 - 0.0095 16.0 6.3 0.0095 16.0 4.4 3.5 2 1 2 4 4 4 1 Flocculin type 3 repeat Dicty_CAD PF05720.7 EJS43967.1 - 0.089 12.4 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Cell-cell adhesion domain Med3 PF11593.3 EJS43967.1 - 6.9 5.8 14.8 8.1 5.5 10.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-RING_4 PF14570.1 EJS43968.1 - 5.6e-20 70.6 13.5 1e-19 69.8 9.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 EJS43968.1 - 2.1e-07 30.6 0.3 8.9e-07 28.6 0.2 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 EJS43968.1 - 2.2e-06 27.0 0.9 2.2e-06 27.0 0.6 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger RRM_1 PF00076.17 EJS43968.1 - 4.6e-06 26.1 0.1 0.00011 21.7 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EJS43968.1 - 5.3e-06 26.0 6.7 1.1e-05 25.0 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 EJS43968.1 - 4.3e-05 23.2 3.0 9.2e-05 22.1 2.1 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.1 EJS43968.1 - 0.0016 18.2 8.9 0.0033 17.2 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain RRM_6 PF14259.1 EJS43968.1 - 0.0021 17.9 0.1 0.0078 16.1 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EJS43968.1 - 0.0074 15.9 10.9 0.016 14.8 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SET_assoc PF11767.3 EJS43968.1 - 0.01 15.1 0.0 0.025 13.8 0.0 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated PocR PF10114.4 EJS43968.1 - 0.033 13.3 0.7 0.25 10.4 0.3 2.2 2 0 0 2 2 2 0 Sensory domain found in PocR zf-UDP PF14569.1 EJS43968.1 - 0.12 12.0 5.4 0.27 10.9 3.7 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.1 EJS43968.1 - 0.16 11.7 9.5 0.32 10.7 6.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EJS43968.1 - 0.68 10.0 11.2 1.4 8.9 7.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EJS43968.1 - 1.7 8.5 11.0 16 5.4 7.7 2.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Ribonuc_red_lgC PF02867.10 EJS43969.1 - 1.7e-215 716.6 0.0 3.2e-215 715.7 0.0 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EJS43969.1 - 2e-23 81.9 0.0 5.5e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EJS43969.1 - 8.3e-16 58.2 0.1 4.6e-15 55.8 0.0 2.4 2 0 0 2 2 2 1 ATP cone domain Tctex-1 PF03645.8 EJS43970.1 - 2.6e-06 27.1 0.1 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF3029 PF11230.3 EJS43970.1 - 0.063 11.4 0.0 0.076 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) DUF202 PF02656.10 EJS43971.1 - 3e-13 49.7 2.8 3e-13 49.7 1.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LHC PF00556.15 EJS43971.1 - 0.011 15.5 0.1 0.037 13.8 0.0 1.9 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit DUF2207 PF09972.4 EJS43971.1 - 3.8 5.9 5.9 16 3.8 4.3 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Aldedh PF00171.17 EJS43972.1 - 1.2e-184 613.9 0.6 1.4e-184 613.7 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EJS43972.1 - 0.00028 19.7 0.0 0.00051 18.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Y_phosphatase PF00102.22 EJS43973.1 - 4.2e-48 163.7 0.1 1.5e-47 161.9 0.0 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EJS43973.1 - 1.2e-11 44.9 0.0 4.5e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EJS43973.1 - 0.0031 17.1 0.0 0.013 15.1 0.0 2.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EJS43973.1 - 0.042 14.0 0.3 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family Peptidase_M24 PF00557.19 EJS43974.1 - 8.6e-50 169.1 0.0 1.3e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EJS43974.1 - 3.5e-33 113.8 0.0 9.6e-33 112.4 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain HTH_24 PF13412.1 EJS43974.1 - 0.16 11.3 1.0 1.2 8.6 0.2 2.5 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding APH PF01636.18 EJS43976.1 - 7.8e-07 29.0 0.0 4.8e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EJS43976.1 - 0.013 15.0 0.0 0.04 13.4 0.0 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EJS43976.1 - 0.02 13.9 0.0 6.2 5.8 0.0 2.6 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2-Hacid_dh_C PF02826.14 EJS43977.1 - 5e-53 178.8 0.0 8.5e-53 178.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EJS43977.1 - 8.5e-39 132.0 0.1 1.2e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EJS43977.1 - 1.7e-05 24.7 1.3 4.2e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EJS43977.1 - 9.8e-05 22.2 0.1 0.00021 21.1 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acetyltransf_1 PF00583.19 EJS43977.1 - 0.0019 18.2 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DUF4367 PF14285.1 EJS43977.1 - 0.0095 15.2 0.3 0.02 14.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4367) BING4CT PF08149.6 EJS43978.1 - 1.8e-38 129.9 0.0 3.3e-36 122.6 0.0 3.6 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 EJS43978.1 - 6.3e-06 25.8 0.0 0.00014 21.6 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat GET2 PF08690.5 EJS43979.1 - 1.8e-102 342.6 2.5 1.3e-101 339.8 1.7 1.8 1 1 0 1 1 1 1 GET complex subunit GET2 PALP PF00291.20 EJS43980.1 - 1.1e-73 248.2 0.2 1.4e-73 247.7 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EJS43980.1 - 4e-43 144.9 0.0 3.8e-29 100.1 0.0 2.7 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase ACT PF01842.20 EJS43980.1 - 0.12 11.9 0.0 9.3 5.8 0.0 2.9 3 0 0 3 3 3 0 ACT domain tRNA-synt_2b PF00587.20 EJS43981.1 - 9.7e-32 109.9 0.0 2.7e-31 108.4 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EJS43981.1 - 0.071 13.0 0.1 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Anticodon binding domain Sec61_beta PF03911.11 EJS43982.1 - 1.9e-17 62.7 0.6 2.4e-17 62.4 0.4 1.1 1 0 0 1 1 1 1 Sec61beta family Myb_DNA-bind_6 PF13921.1 EJS43983.1 - 7.6e-10 38.7 1.8 1.9e-09 37.4 0.2 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EJS43983.1 - 7.7e-08 32.2 0.5 2.7e-07 30.5 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Chorion_2 PF03964.10 EJS43983.1 - 4.7 7.8 13.8 2.8 8.5 4.9 3.0 2 0 0 2 2 2 0 Chorion family 2 Chorismate_bind PF00425.13 EJS43984.1 - 1.9e-86 289.6 0.0 1.4e-85 286.7 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EJS43984.1 - 5.8e-30 104.1 0.0 2.2e-27 95.8 0.0 3.2 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region POR PF01558.13 EJS43984.1 - 0.041 13.7 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Meth_synt_2 PF01717.13 EJS43985.1 - 1.8e-145 483.9 0.0 5e-140 466.0 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EJS43985.1 - 2e-128 428.0 0.0 6.3e-114 380.4 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Imm3 PF14425.1 EJS43986.1 - 0.067 13.1 0.3 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 Immunity protein Imm3 RICTOR_N PF14664.1 EJS43987.1 - 2.5e-107 358.7 9.2 4.9e-107 357.7 6.4 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EJS43987.1 - 9.3e-76 253.7 1.9 9.3e-76 253.7 1.3 3.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EJS43987.1 - 9.3e-33 112.6 1.6 2.7e-32 111.1 0.1 2.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EJS43987.1 - 1e-30 105.4 0.2 2.1e-29 101.2 0.1 3.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 Proteasome PF00227.21 EJS43988.1 - 3.6e-41 140.5 0.0 4.4e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Rad51 PF08423.6 EJS43989.1 - 2.5e-136 452.5 0.0 3.3e-136 452.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EJS43989.1 - 2.4e-13 49.9 0.0 3.8e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EJS43989.1 - 1.3e-11 44.4 0.8 3.4e-11 43.1 0.6 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EJS43989.1 - 2.4e-11 43.2 0.0 4.5e-11 42.3 0.0 1.4 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 EJS43989.1 - 1.1e-05 24.6 0.0 1.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 EJS43989.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EJS43989.1 - 0.04 12.8 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain HHH PF00633.18 EJS43989.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sel1 PF08238.7 EJS43990.1 - 4.6e-19 68.4 3.3 8.6e-05 23.0 0.1 4.8 5 0 0 5 5 5 4 Sel1 repeat AKAP2_C PF15304.1 EJS43990.1 - 0.049 13.2 0.9 0.098 12.2 0.6 1.5 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus UCH PF00443.24 EJS43991.1 - 1.5e-82 276.7 14.7 5.1e-82 275.0 10.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EJS43991.1 - 1.6e-25 90.2 2.8 3.4e-22 79.2 0.1 3.8 3 1 1 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase Pribosyltran_N PF13793.1 EJS43992.1 - 1.6e-42 143.9 0.0 2.7e-40 136.7 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EJS43992.1 - 1.7e-35 122.4 2.1 8.1e-29 100.6 0.8 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EJS43992.1 - 2.7e-13 49.7 0.2 4.1e-12 45.9 0.2 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EJS43992.1 - 0.0036 16.5 0.1 0.0052 16.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UQ_con PF00179.21 EJS43993.1 - 2e-28 98.5 0.2 3.2e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EJS43993.1 - 0.0055 16.5 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EJS43993.1 - 0.045 13.5 0.0 0.096 12.4 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B ADH_zinc_N_2 PF13602.1 EJS43994.1 - 1.8e-12 48.2 0.0 6.7e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EJS43994.1 - 1.8e-06 27.6 0.1 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_S8e PF01201.17 EJS43995.1 - 6.6e-51 171.9 2.4 7.5e-51 171.7 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e HSP70 PF00012.15 EJS43996.1 - 7.5e-270 896.0 8.6 8.6e-270 895.8 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EJS43996.1 - 2.8e-17 62.3 0.0 3.4e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EJS43996.1 - 0.00033 20.3 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EJS43996.1 - 0.017 14.2 0.1 0.093 11.8 0.0 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DDR PF08841.5 EJS43996.1 - 0.037 12.8 0.4 0.63 8.8 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain WD40 PF00400.27 EJS43997.1 - 5.5e-24 83.1 5.8 7.9e-05 22.3 0.2 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 EJS43997.1 - 0.029 12.5 0.1 0.18 9.9 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 LisH PF08513.6 EJS43998.1 - 2.9e-05 23.6 0.1 5e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 LisH HEAT_EZ PF13513.1 EJS43999.1 - 9.7e-18 64.1 0.1 0.0017 18.8 0.0 8.6 9 0 0 9 9 9 4 HEAT-like repeat HEAT_2 PF13646.1 EJS43999.1 - 5.2e-14 52.3 3.1 0.0051 17.0 0.0 6.9 6 2 2 8 8 8 5 HEAT repeats IBN_N PF03810.14 EJS43999.1 - 5.7e-14 51.7 3.5 2.4e-10 40.1 0.1 4.3 4 0 0 4 4 4 2 Importin-beta N-terminal domain HEAT PF02985.17 EJS43999.1 - 5.3e-13 47.8 0.7 0.045 13.8 0.0 8.9 9 0 0 9 9 9 2 HEAT repeat Cnd1 PF12717.2 EJS43999.1 - 0.011 15.5 12.0 0.93 9.3 0.2 5.3 3 3 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 EJS43999.1 - 0.075 13.0 0.6 4.8 7.1 0.0 4.4 5 1 1 6 6 6 0 Rix1 complex component involved in 60S ribosome maturation Ank PF00023.25 EJS44000.1 - 5.9e-10 38.4 2.9 0.00053 19.6 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EJS44000.1 - 1.6e-07 31.6 3.3 0.011 16.2 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EJS44000.1 - 6.8e-07 29.5 9.1 0.0051 17.1 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) KilA-N PF04383.8 EJS44000.1 - 2.1e-06 27.3 2.7 2.1e-06 27.3 1.9 4.1 2 2 0 2 2 2 1 KilA-N domain Ank_3 PF13606.1 EJS44000.1 - 3.2e-06 26.8 0.8 0.086 13.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EJS44000.1 - 0.64 10.3 15.3 0.33 11.2 0.1 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) LSM PF01423.17 EJS44001.1 - 6.2e-17 60.9 0.9 6.2e-17 60.9 0.6 1.6 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.1 EJS44001.1 - 1.7e-05 24.6 0.0 4.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain SH3_1 PF00018.23 EJS44002.1 - 2.9e-14 52.1 0.2 6.4e-14 51.0 0.2 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EJS44002.1 - 3.5e-14 52.8 0.0 3.5e-14 52.8 0.0 2.9 2 1 0 2 2 2 1 PH domain SAM_2 PF07647.12 EJS44002.1 - 8.8e-12 44.6 0.1 1.8e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EJS44002.1 - 4.9e-10 39.6 0.0 3.6e-09 36.8 0.0 2.7 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_9 PF14604.1 EJS44002.1 - 8.1e-07 28.5 0.1 1.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 EJS44002.1 - 4.8e-05 23.3 0.0 0.0077 16.2 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.25 EJS44002.1 - 0.00069 19.7 0.1 0.0013 18.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 EJS44002.1 - 0.0014 18.0 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4 PF00097.20 EJS44004.1 - 3.7e-07 29.6 14.4 6.7e-07 28.8 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EJS44004.1 - 1.2e-06 28.2 14.8 2.5e-06 27.2 10.3 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EJS44004.1 - 4.1e-06 26.3 13.1 8.1e-06 25.4 9.1 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EJS44004.1 - 1.7e-05 24.6 11.5 4.6e-05 23.3 8.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EJS44004.1 - 4.1e-05 23.2 8.4 0.00011 21.8 5.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EJS44004.1 - 0.00066 19.3 14.2 0.0022 17.6 9.9 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EJS44004.1 - 0.092 12.6 15.1 0.16 11.8 10.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EJS44004.1 - 4.8 7.3 9.6 13 5.9 6.7 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger SH3_1 PF00018.23 EJS44005.1 - 1.6e-12 46.5 0.2 2.8e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EJS44005.1 - 2.8e-11 42.8 0.1 4.5e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EJS44005.1 - 1.8e-07 30.5 0.0 3.9e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Variant SH3 domain Phage_holin_4 PF05105.7 EJS44005.1 - 0.098 12.3 1.8 0.17 11.5 1.2 1.3 1 0 0 1 1 1 0 Holin family Aa_trans PF01490.13 EJS44006.1 - 2.7e-118 395.0 29.6 3e-118 394.8 20.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EJS44006.1 - 1.1e-10 40.9 16.4 1.1e-10 40.9 11.4 1.9 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family Motile_Sperm PF00635.21 EJS44007.1 - 1.7e-26 91.9 1.0 3.2e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 MSP (Major sperm protein) domain ArfGap PF01412.13 EJS44008.1 - 9.2e-34 115.7 0.9 9.2e-34 115.7 0.6 2.4 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf Pkinase PF00069.20 EJS44009.1 - 9.7e-27 93.7 0.3 2e-26 92.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44009.1 - 9.8e-07 28.0 0.0 1.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3354 PF11834.3 EJS44009.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) HECT PF00632.20 EJS44011.1 - 9.7e-91 304.2 0.0 1.3e-90 303.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EJS44011.1 - 5.3e-34 115.7 19.7 6.7e-11 41.8 1.0 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EJS44011.1 - 3.3e-16 58.9 0.2 8.6e-16 57.5 0.2 1.7 1 0 0 1 1 1 1 C2 domain Macoilin PF09726.4 EJS44011.1 - 6.4 4.9 8.0 9.1 4.4 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_S8e PF01201.17 EJS44012.1 - 3.2e-39 134.0 7.9 1.8e-38 131.6 5.5 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.7 EJS44012.1 - 0.037 13.6 0.1 0.074 12.7 0.1 1.4 1 0 0 1 1 1 0 Homeo-prospero domain YebF PF13995.1 EJS44012.1 - 0.11 12.5 0.1 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 YebF-like protein DUF3959 PF13105.1 EJS44012.1 - 9.1 5.5 10.1 4 6.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Sas10_Utp3 PF04000.10 EJS44013.1 - 4.6e-09 36.3 0.6 4.6e-09 36.3 0.4 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family MRP-S31 PF15433.1 EJS44013.1 - 6 6.1 13.3 5 6.4 7.9 1.8 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S31 zf-C2H2 PF00096.21 EJS44014.1 - 1.3e-10 40.9 20.3 4e-06 26.8 2.3 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS44014.1 - 2.4e-09 36.8 12.1 0.0001 22.3 1.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EJS44014.1 - 1.4e-06 28.2 12.9 0.003 17.6 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EJS44014.1 - 6.6e-06 26.1 11.5 0.0049 17.0 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EJS44014.1 - 0.00023 21.3 19.3 0.00023 21.2 4.8 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-BED PF02892.10 EJS44014.1 - 0.017 14.8 9.1 0.58 9.9 2.8 2.8 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EJS44014.1 - 0.02 14.7 0.6 0.02 14.7 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 EJS44014.1 - 0.04 14.0 6.8 0.073 13.2 4.7 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.6 EJS44014.1 - 0.071 12.7 1.1 0.17 11.4 0.8 1.7 1 0 0 1 1 1 0 GAGA factor zf-C2H2_2 PF12756.2 EJS44014.1 - 0.12 12.4 7.6 3.9 7.6 0.7 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Elf1 PF05129.8 EJS44014.1 - 5.2 6.8 9.6 9 6.0 2.0 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.1 EJS44014.1 - 8.1 6.2 9.3 21 4.9 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Ribosomal_S26e PF01283.14 EJS44015.1 - 1.8e-50 169.9 7.8 2.1e-50 169.7 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1101 PF06503.6 EJS44015.1 - 0.019 13.8 0.1 0.02 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) ICL PF00463.16 EJS44016.1 - 1.2e-286 950.9 0.2 1.4e-286 950.7 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EJS44016.1 - 1.6e-09 37.3 0.0 3.5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 EJS44016.1 - 0.069 12.6 0.1 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain HisG PF01634.13 EJS44017.1 - 6.3e-54 181.9 0.6 8.6e-54 181.5 0.4 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EJS44017.1 - 3.3e-28 97.4 0.0 6.2e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain Transp_cyt_pur PF02133.10 EJS44018.1 - 3e-117 391.8 40.4 3.5e-117 391.6 28.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ribonuc_L-PSP PF01042.16 EJS44019.1 - 9.7e-43 144.7 1.0 1.1e-42 144.6 0.7 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4488 PF14869.1 EJS44019.1 - 0.022 14.3 0.1 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) DUF896 PF05979.7 EJS44020.1 - 7.4 6.2 6.7 1.7 8.3 1.9 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Cyclin PF08613.6 EJS44021.1 - 4.3e-44 150.5 0.2 8.1e-25 87.9 0.0 2.5 2 0 0 2 2 2 2 Cyclin HAD_2 PF13419.1 EJS44022.1 - 4.7e-13 49.7 0.0 6.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EJS44022.1 - 8.8e-09 36.0 0.0 2.5e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EJS44022.1 - 3.1e-07 29.9 0.0 5.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EJS44022.1 - 0.0083 16.3 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SAP PF02037.22 EJS44023.1 - 2.5e-12 45.9 0.5 4.4e-12 45.1 0.3 1.5 1 0 0 1 1 1 1 SAP domain Packaging_FI PF14000.1 EJS44023.1 - 0.58 10.3 8.7 0.11 12.6 2.8 2.1 2 0 0 2 2 2 0 DNA packaging protein FI DDOST_48kD PF03345.9 EJS44024.1 - 2.8e-134 447.8 1.5 3.2e-134 447.6 1.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF1129 PF06570.6 EJS44025.1 - 0.13 11.5 0.0 0.33 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Nop16 PF09420.5 EJS44026.1 - 4.1e-62 209.1 8.6 4.8e-62 208.8 5.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 NAD_binding_10 PF13460.1 EJS44027.1 - 5.7e-13 49.2 0.0 7.7e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 EJS44027.1 - 8.7e-08 31.0 0.0 9.7e-07 27.5 0.0 2.2 1 1 2 3 3 3 1 HIM1 NmrA PF05368.8 EJS44027.1 - 0.0027 17.0 0.0 0.0055 15.9 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EJS44027.1 - 0.0091 15.4 0.0 0.019 14.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDA1_CD39 PF01150.12 EJS44028.1 - 2.4e-163 543.7 0.0 2.6e-162 540.2 0.0 1.9 2 0 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EJS44028.1 - 0.23 10.6 0.0 0.45 9.6 0.0 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family GN3L_Grn1 PF08701.6 EJS44029.1 - 1.8e-23 82.2 19.0 5.9e-23 80.5 13.2 2.0 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EJS44029.1 - 5.1e-22 78.0 0.1 7.7e-16 58.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EJS44029.1 - 3.1e-07 29.7 0.0 5.6e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EJS44029.1 - 3.4e-06 26.9 2.3 0.094 12.5 0.0 3.9 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EJS44029.1 - 7.5e-06 25.4 0.0 0.038 13.4 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EJS44029.1 - 1.9e-05 23.8 0.0 0.00011 21.3 0.0 2.0 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 EJS44029.1 - 0.00049 19.3 0.1 0.00093 18.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EJS44029.1 - 0.006 17.0 0.1 0.39 11.2 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 EJS44029.1 - 0.0071 15.8 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EJS44029.1 - 0.01 16.1 1.6 0.025 14.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 EJS44029.1 - 0.06 12.1 1.5 0.072 11.8 0.0 1.8 2 0 0 2 2 2 0 ArgK protein MobB PF03205.9 EJS44029.1 - 0.11 12.2 0.5 0.58 9.8 0.0 2.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EJS44029.1 - 0.15 12.0 1.1 0.39 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EJS44029.1 - 0.19 12.5 2.3 0.78 10.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain NTF2 PF02136.15 EJS44030.1 - 9e-36 122.8 0.4 1e-35 122.6 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 EJS44030.1 - 0.0022 17.0 0.1 0.0035 16.4 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) Methyltransf_6 PF03737.10 EJS44031.1 - 3e-42 144.1 0.0 3.7e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase SRP1_TIP1 PF00660.12 EJS44032.1 - 1.4e-41 140.5 0.9 3.4e-41 139.2 0.7 1.6 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.14 EJS44032.1 - 3.2e-08 32.6 7.6 1.5e-07 30.5 5.3 2.3 1 0 0 1 1 1 1 Yeast PIR protein repeat SLD3 PF08639.5 EJS44032.1 - 0.0052 15.4 13.9 0.0082 14.8 9.6 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 FAM196 PF15265.1 EJS44032.1 - 0.049 12.8 10.1 0.051 12.8 7.0 1.1 1 0 0 1 1 1 0 FAM196 family Spc42p PF11544.3 EJS44032.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Spindle pole body component Spc42p TFIIA PF03153.8 EJS44032.1 - 0.42 10.4 12.9 0.53 10.1 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.1 EJS44032.1 - 1.1 9.5 11.5 2.1 8.6 8.0 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Med3 PF11593.3 EJS44032.1 - 2 7.5 32.6 3.1 6.9 22.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Macoilin PF09726.4 EJS44032.1 - 5.2 5.2 25.1 7.7 4.6 17.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Herpes_BLLF1 PF05109.8 EJS44032.1 - 5.3 4.8 27.9 6.2 4.6 19.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SRP-alpha_N PF04086.8 EJS44032.1 - 5.9 6.1 12.4 7.6 5.8 8.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2413 PF10310.4 EJS44032.1 - 6 5.5 22.6 9.1 4.9 15.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CytochromB561_N PF09786.4 EJS44032.1 - 8 4.7 17.7 8.4 4.7 12.3 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Hex_IIIa PF02455.11 EJS44032.1 - 8.9 4.8 11.1 14 4.1 7.7 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Proteasome PF00227.21 EJS44033.1 - 9.8e-44 148.9 0.0 1.1e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit OB_NTP_bind PF07717.11 EJS44034.1 - 3.8e-27 94.3 0.0 1e-26 92.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EJS44034.1 - 4.4e-26 90.8 0.0 4.4e-26 90.8 0.0 2.4 3 0 0 3 3 2 1 Helicase associated domain (HA2) S1 PF00575.18 EJS44034.1 - 9.1e-13 48.1 0.5 3e-12 46.4 0.1 2.1 2 0 0 2 2 1 1 S1 RNA binding domain Helicase_C PF00271.26 EJS44034.1 - 1.2e-12 47.4 0.0 6.2e-12 45.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EJS44034.1 - 2.7e-05 23.7 0.3 9.7e-05 21.9 0.2 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EJS44034.1 - 5.4e-05 23.3 0.0 0.00018 21.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EJS44034.1 - 0.00024 20.0 0.0 0.0015 17.5 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 EJS44034.1 - 0.00055 20.2 1.2 0.31 11.3 0.0 4.1 4 0 0 4 4 3 1 ABC transporter AAA_30 PF13604.1 EJS44034.1 - 0.014 15.0 0.1 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EJS44034.1 - 0.014 15.3 0.0 0.15 11.9 0.0 2.6 1 1 0 1 1 1 0 AAA domain PWI PF01480.12 EJS44034.1 - 0.021 14.9 1.1 1.5 8.9 0.1 2.9 1 1 1 2 2 2 0 PWI domain Sigma54_activ_2 PF14532.1 EJS44034.1 - 0.024 14.6 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 EJS44034.1 - 0.8 10.0 0.0 0.8 10.0 0.0 3.7 3 1 0 3 3 2 0 AAA domain DUF3682 PF12446.3 EJS44034.1 - 1.9 8.7 5.2 30 4.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) NAD_binding_8 PF13450.1 EJS44035.1 - 2.1e-12 46.8 0.0 4.4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EJS44035.1 - 9.3e-08 31.5 0.0 1.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EJS44035.1 - 2.3e-06 26.7 0.1 2.3e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EJS44035.1 - 1.8e-05 25.0 0.3 0.008 16.5 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EJS44035.1 - 0.00088 18.4 0.0 0.0022 17.1 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EJS44035.1 - 0.0095 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding EB1 PF03271.12 EJS44036.1 - 4.1e-20 71.5 0.2 8.4e-20 70.5 0.1 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EJS44036.1 - 8.7e-07 28.9 0.3 1.6e-06 28.1 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain IncA PF04156.9 EJS44036.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 IncA protein Sec61_beta PF03911.11 EJS44037.1 - 5e-16 58.2 0.3 6.3e-16 57.8 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family G-alpha PF00503.15 EJS44038.1 - 4.2e-114 381.2 9.6 1.2e-113 379.7 6.6 1.6 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EJS44038.1 - 1e-15 57.4 0.9 2.1e-10 40.1 0.2 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EJS44038.1 - 0.001 18.2 0.2 0.21 10.7 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EJS44038.1 - 0.0014 19.0 0.3 0.79 10.2 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EJS44038.1 - 0.015 14.7 0.1 0.038 13.4 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EJS44038.1 - 0.025 14.0 0.8 4.9 6.5 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EJS44038.1 - 0.033 13.6 0.2 0.17 11.4 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain CPT PF07931.7 EJS44038.1 - 0.11 12.1 0.1 7.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PCI PF01399.22 EJS44039.1 - 1.3e-20 73.6 2.7 2.9e-20 72.5 0.4 2.5 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 EJS44039.1 - 2.6e-20 72.5 4.0 2.6e-20 72.5 2.8 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI_Csn8 PF10075.4 EJS44039.1 - 0.0023 17.7 0.1 0.0057 16.4 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 MarR_2 PF12802.2 EJS44039.1 - 0.054 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 MarR family TPR_15 PF13429.1 EJS44039.1 - 0.11 11.5 0.9 5.2 6.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Med17 PF10156.4 EJS44040.1 - 1.7e-145 484.9 26.2 1.7e-145 484.9 18.2 2.2 2 1 0 2 2 2 1 Subunit 17 of Mediator complex P5CR_dimer PF14748.1 EJS44041.1 - 9e-33 112.4 0.2 1.5e-32 111.8 0.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EJS44041.1 - 5.8e-11 42.6 0.1 1.4e-10 41.4 0.1 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EJS44041.1 - 0.028 14.1 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Carn_acyltransf PF00755.15 EJS44042.1 - 1.9e-79 267.3 0.2 6.1e-63 212.8 0.0 2.2 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase GTP_EFTU PF00009.22 EJS44043.1 - 1.8e-38 131.8 0.0 3.1e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EJS44043.1 - 2.3e-36 123.6 0.2 5.3e-36 122.5 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EJS44043.1 - 5.7e-11 42.3 0.6 5.7e-11 42.3 0.4 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EJS44043.1 - 0.0063 16.4 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase CDP-OH_P_transf PF01066.16 EJS44044.1 - 7.7e-12 45.4 3.3 1.5e-11 44.4 2.3 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase E1-E2_ATPase PF00122.15 EJS44044.1 - 0.14 11.2 0.0 0.8 8.6 0.0 1.9 2 0 0 2 2 2 0 E1-E2 ATPase AMPKBI PF04739.10 EJS44045.1 - 7.1e-33 112.4 4.4 7.1e-33 112.4 3.0 2.1 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Ras PF00071.17 EJS44046.1 - 6.8e-61 204.3 0.2 8.1e-61 204.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS44046.1 - 1.3e-19 70.8 0.0 2.4e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS44046.1 - 1.2e-13 50.6 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EJS44046.1 - 8.9e-07 28.8 0.0 1.5e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EJS44046.1 - 0.0002 20.8 0.0 0.001 18.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.9 EJS44046.1 - 0.00037 19.5 0.0 0.00048 19.2 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_15 PF13175.1 EJS44046.1 - 0.00077 18.6 0.5 0.0012 17.9 0.4 1.5 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 EJS44046.1 - 0.001 18.2 0.0 0.0016 17.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EJS44046.1 - 0.0021 17.2 0.9 0.0049 16.0 0.1 1.9 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EJS44046.1 - 0.0054 16.8 0.1 0.027 14.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain TraG_N PF07916.6 EJS44046.1 - 0.0063 15.0 0.2 0.0078 14.6 0.1 1.1 1 0 0 1 1 1 1 TraG-like protein, N-terminal region PduV-EutP PF10662.4 EJS44046.1 - 0.025 14.0 0.0 0.037 13.5 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EJS44046.1 - 0.027 14.7 0.3 0.045 14.0 0.2 1.6 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 EJS44046.1 - 0.039 13.1 0.1 0.17 11.1 0.0 1.8 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EJS44046.1 - 0.04 13.9 0.3 0.097 12.6 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.13 EJS44046.1 - 0.047 12.7 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_14 PF13173.1 EJS44046.1 - 0.047 13.5 0.1 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EJS44046.1 - 0.055 12.7 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.1 EJS44046.1 - 0.14 12.4 0.2 0.77 10.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain Formyl_trans_N PF00551.14 EJS44046.1 - 0.15 11.6 0.1 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Formyl transferase DUF2362 PF10154.4 EJS44048.1 - 1.1 7.7 4.9 1.3 7.6 3.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Spore_coat_CotO PF14153.1 EJS44048.1 - 2.3 7.5 8.5 0.29 10.5 2.2 1.8 1 1 1 2 2 2 0 Spore coat protein CotO PNRC PF15365.1 EJS44049.1 - 0.21 11.6 2.2 0.36 10.8 0.0 2.5 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator ABC_tran PF00005.22 EJS44050.1 - 1.3e-49 168.0 0.0 1.3e-24 87.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EJS44050.1 - 5e-23 82.4 2.1 1.3e-06 28.5 0.0 4.3 2 2 1 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 EJS44050.1 - 1e-20 73.3 1.9 1e-20 73.3 1.3 2.9 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 EJS44050.1 - 4.6e-10 39.1 0.9 0.47 9.6 0.0 4.5 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EJS44050.1 - 2.3e-08 33.4 0.0 0.0022 17.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EJS44050.1 - 2.4e-08 34.3 0.1 0.0061 16.8 0.0 3.4 4 1 0 4 4 3 2 AAA domain AAA_22 PF13401.1 EJS44050.1 - 5.4e-08 33.0 0.0 0.014 15.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EJS44050.1 - 5.8e-08 33.2 0.0 0.0025 18.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EJS44050.1 - 5.8e-08 33.5 0.0 0.0045 17.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EJS44050.1 - 2.4e-07 30.0 0.0 0.00017 20.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 EJS44050.1 - 4.9e-06 26.3 0.7 0.061 12.9 0.0 2.8 3 0 0 3 3 2 2 NACHT domain MMR_HSR1 PF01926.18 EJS44050.1 - 8.2e-06 25.7 0.1 0.036 14.0 0.0 3.1 3 2 0 3 3 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.17 EJS44050.1 - 1.6e-05 25.0 0.0 0.18 11.9 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 EJS44050.1 - 2.7e-05 24.3 0.1 0.2 11.8 0.0 3.4 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EJS44050.1 - 6.8e-05 22.8 0.0 0.38 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EJS44050.1 - 8.4e-05 21.7 0.2 0.78 8.7 0.0 3.7 4 1 0 4 4 4 2 AAA ATPase domain MCM PF00493.18 EJS44050.1 - 9.2e-05 21.3 2.0 0.27 9.9 0.0 3.1 3 0 0 3 3 3 2 MCM2/3/5 family AAA_14 PF13173.1 EJS44050.1 - 0.00011 22.0 0.0 0.66 9.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EJS44050.1 - 0.00013 22.3 15.4 0.028 14.7 0.0 3.8 4 1 0 4 4 3 2 AAA domain AAA_10 PF12846.2 EJS44050.1 - 0.00016 21.2 0.0 0.49 9.7 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain AAA_33 PF13671.1 EJS44050.1 - 0.00017 21.4 0.0 0.34 10.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EJS44050.1 - 0.00026 21.0 1.5 0.35 10.8 0.1 3.4 3 2 0 3 3 3 1 AAA ATPase domain VirE PF05272.6 EJS44050.1 - 0.00027 20.4 0.2 0.36 10.2 0.0 3.0 3 0 0 3 3 3 1 Virulence-associated protein E MobB PF03205.9 EJS44050.1 - 0.00037 20.1 0.1 0.011 15.4 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EJS44050.1 - 0.00042 19.3 0.0 0.015 14.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 EJS44050.1 - 0.00044 19.7 0.0 0.55 9.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EJS44050.1 - 0.0011 18.8 3.6 0.75 9.5 0.0 4.0 3 1 0 4 4 3 1 Dynamin family AAA_5 PF07728.9 EJS44050.1 - 0.0033 17.1 0.0 2.9 7.6 0.1 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EJS44050.1 - 0.0042 15.8 0.1 1 7.9 0.0 2.5 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein ArgK PF03308.11 EJS44050.1 - 0.007 15.1 0.0 1.3 7.7 0.0 2.6 3 0 0 3 3 2 1 ArgK protein NB-ARC PF00931.17 EJS44050.1 - 0.0084 14.9 0.0 2.1 7.1 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain DUF815 PF05673.8 EJS44050.1 - 0.0088 15.0 0.1 4.5 6.1 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 EJS44050.1 - 0.011 15.5 0.0 11 5.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 EJS44050.1 - 0.013 15.4 0.4 1.3 8.9 0.0 3.3 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 EJS44050.1 - 0.018 14.7 4.3 2.6 7.6 0.0 3.4 4 1 0 4 4 3 0 Archaeal ATPase PduV-EutP PF10662.4 EJS44050.1 - 0.019 14.4 0.3 7.7 5.9 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DAP3 PF10236.4 EJS44050.1 - 0.023 13.6 2.1 5.5 5.8 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 FtsK_SpoIIIE PF01580.13 EJS44050.1 - 0.029 13.8 0.0 2.9 7.3 0.0 2.9 2 1 0 3 3 3 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 EJS44050.1 - 0.042 13.5 0.1 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 NTPase DUF2813 PF11398.3 EJS44050.1 - 0.049 12.7 0.2 4.9 6.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) Sigma54_activ_2 PF14532.1 EJS44050.1 - 0.056 13.4 0.0 19 5.2 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain FeoB_N PF02421.13 EJS44050.1 - 0.076 12.2 0.1 2.9 7.1 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B G-alpha PF00503.15 EJS44050.1 - 0.33 9.5 4.6 13 4.2 1.6 3.1 3 1 0 3 3 3 0 G-protein alpha subunit HAD_2 PF13419.1 EJS44051.1 - 2.1e-20 73.6 0.1 3e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EJS44051.1 - 2.7e-05 24.6 0.0 0.0082 16.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Nse5 PF08691.5 EJS44052.1 - 1.3e-57 195.4 24.5 1.8e-57 195.0 16.9 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Anophelin PF10731.4 EJS44052.1 - 3.3 7.8 8.4 10 6.2 5.8 1.9 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito UAA PF08449.6 EJS44053.1 - 5.3e-12 45.2 15.3 6.2e-12 45.0 10.6 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EJS44053.1 - 1e-08 34.9 9.6 1e-08 34.9 6.7 2.1 1 1 1 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EJS44053.1 - 0.0073 16.3 21.8 0.0093 16.0 6.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EJS44053.1 - 0.032 13.3 6.6 0.0074 15.4 2.1 1.7 2 0 0 2 2 2 0 Nucleotide-sugar transporter PHO4 PF01384.15 EJS44053.1 - 0.14 10.8 7.7 0.093 11.3 2.9 2.1 1 1 2 3 3 3 0 Phosphate transporter family TRAP-gamma PF07074.7 EJS44053.1 - 0.76 9.2 6.5 0.36 10.3 1.2 2.4 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Multi_Drug_Res PF00893.14 EJS44053.1 - 1.7 9.1 7.1 13 6.2 1.0 2.6 2 1 0 2 2 2 0 Small Multidrug Resistance protein ER_lumen_recept PF00810.13 EJS44053.1 - 4.5 7.7 10.7 0.13 12.7 1.4 2.6 2 1 1 3 3 3 0 ER lumen protein retaining receptor GATA PF00320.22 EJS44054.1 - 7.7e-16 57.1 3.3 7.7e-16 57.1 2.3 2.3 3 0 0 3 3 3 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EJS44054.1 - 0.17 11.2 0.6 0.36 10.2 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding PMSR PF01625.16 EJS44055.1 - 1.3e-48 164.7 0.1 1.7e-48 164.4 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase AdoHcyase PF05221.12 EJS44056.1 - 1.1e-142 473.7 0.0 1.3e-142 473.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EJS44056.1 - 1.3e-85 285.2 2.7 2.1e-85 284.5 1.9 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EJS44056.1 - 3.7e-07 29.4 0.1 6.5e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EJS44056.1 - 0.00051 20.0 0.1 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.7 EJS44056.1 - 0.001 18.4 0.3 0.0018 17.6 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 EJS44056.1 - 0.062 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Erg28 PF03694.8 EJS44057.1 - 2.2e-45 153.2 2.0 2.7e-45 152.9 1.4 1.1 1 0 0 1 1 1 1 Erg28 like protein MtN3_slv PF03083.11 EJS44057.1 - 0.0017 18.2 0.6 0.0046 16.7 0.4 1.8 1 1 1 2 2 2 1 Sugar efflux transporter for intercellular exchange Pex24p PF06398.6 EJS44058.1 - 0.096 11.4 3.0 0.11 11.2 2.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin AAA PF00004.24 EJS44059.1 - 6e-40 136.5 0.0 1.4e-39 135.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EJS44059.1 - 4.4e-06 26.4 0.0 7.9e-05 22.4 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EJS44059.1 - 9.4e-06 25.7 0.1 0.00022 21.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EJS44059.1 - 4.6e-05 22.5 0.0 0.0001 21.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EJS44059.1 - 5.4e-05 23.2 0.0 0.036 14.0 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EJS44059.1 - 0.00011 22.1 0.0 0.00027 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EJS44059.1 - 0.0006 19.7 0.0 0.015 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EJS44059.1 - 0.00075 18.9 0.5 0.27 10.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.8 EJS44059.1 - 0.00084 18.1 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EJS44059.1 - 0.0009 18.9 0.1 0.0061 16.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EJS44059.1 - 0.0027 17.1 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EJS44059.1 - 0.0027 17.6 0.2 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EJS44059.1 - 0.004 16.3 0.1 0.0092 15.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EJS44059.1 - 0.0061 17.3 0.3 0.072 13.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EJS44059.1 - 0.0074 16.1 0.0 0.026 14.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EJS44059.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 EJS44059.1 - 0.014 14.3 0.0 0.03 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Chromo PF00385.19 EJS44059.1 - 0.036 13.7 0.0 0.097 12.3 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PhoH PF02562.11 EJS44059.1 - 0.098 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EJS44059.1 - 0.11 12.1 0.0 0.39 10.3 0.0 2.0 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EJS44059.1 - 0.18 12.0 3.4 0.23 11.7 0.0 2.8 3 1 0 3 3 3 0 AAA domain Complex1_LYR_1 PF13232.1 EJS44060.1 - 4.3e-17 62.0 0.7 5.3e-17 61.7 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EJS44060.1 - 2.3e-15 56.1 0.4 2.9e-15 55.7 0.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MIF4G PF02854.14 EJS44060.1 - 0.0028 17.0 0.2 0.0031 16.9 0.2 1.2 1 0 0 1 1 1 1 MIF4G domain Phyto_Pns9_10 PF05878.6 EJS44060.1 - 0.03 13.3 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF1851 PF08906.6 EJS44060.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1851) Cupin_8 PF13621.1 EJS44061.1 - 1e-06 28.4 4.5 4.9e-06 26.2 2.5 2.2 1 1 1 2 2 2 1 Cupin-like domain PHD PF00628.24 EJS44061.1 - 0.00061 19.4 5.2 0.00061 19.4 3.6 2.0 2 0 0 2 2 2 1 PHD-finger JmjC PF02373.17 EJS44061.1 - 0.008 16.4 0.0 0.18 12.0 0.0 2.9 2 1 0 2 2 2 1 JmjC domain, hydroxylase C1_1 PF00130.17 EJS44061.1 - 0.041 13.6 5.8 0.088 12.5 4.0 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cupin_4 PF08007.7 EJS44061.1 - 0.06 12.5 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.6 EJS44061.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain DUF1423 PF07227.6 EJS44061.1 - 1 7.9 7.0 0.3 9.7 2.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) Mito_carr PF00153.22 EJS44062.1 - 3.6e-47 158.0 7.2 1.4e-17 63.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Gti1_Pac2 PF09729.4 EJS44064.1 - 2.1e-56 190.3 0.0 2.1e-56 190.3 0.0 3.6 3 1 0 3 3 3 1 Gti1/Pac2 family UAA PF08449.6 EJS44066.1 - 5.4e-89 298.1 13.9 6.1e-89 297.9 9.6 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EJS44066.1 - 3.4e-08 33.2 5.5 3.4e-08 33.2 3.8 2.7 2 2 0 2 2 2 1 Triose-phosphate Transporter family Phage_holin PF04688.8 EJS44066.1 - 0.096 12.2 1.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Phage lysis protein, holin PIRT PF15099.1 EJS44066.1 - 0.72 9.0 4.0 4.2 6.5 1.5 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family EamA PF00892.15 EJS44066.1 - 1.2 9.1 21.2 0.28 11.2 3.5 2.9 3 1 0 3 3 3 0 EamA-like transporter family TPP_enzyme_N PF02776.13 EJS44067.1 - 7.4e-42 142.7 0.0 1.1e-40 138.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EJS44067.1 - 3.1e-25 88.5 0.0 1e-24 86.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EJS44067.1 - 8.7e-20 70.8 0.1 5.5e-19 68.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain zf-Nse PF11789.3 EJS44068.1 - 3.9e-22 77.5 1.7 5.3e-22 77.0 0.5 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EJS44068.1 - 0.0009 18.9 0.4 0.0028 17.3 0.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EJS44068.1 - 0.0039 16.9 0.5 0.0039 16.9 0.3 2.3 2 1 1 3 3 3 1 Ring finger domain zf-Apc11 PF12861.2 EJS44068.1 - 0.0067 16.2 0.5 0.015 15.0 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HR1 PF02185.11 EJS44068.1 - 0.01 15.5 0.0 0.047 13.4 0.0 2.0 2 0 0 2 2 2 0 Hr1 repeat zf-MIZ PF02891.15 EJS44068.1 - 0.01 15.3 0.8 0.01 15.3 0.6 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.20 EJS44068.1 - 0.011 15.4 0.4 0.029 14.0 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EJS44068.1 - 0.017 15.2 0.1 0.046 13.8 0.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Fzo_mitofusin PF04799.8 EJS44068.1 - 0.4 10.0 2.2 1.4 8.3 0.2 2.0 2 0 0 2 2 2 0 fzo-like conserved region PCI PF01399.22 EJS44069.1 - 0.076 13.3 0.6 0.23 11.7 0.0 2.2 2 1 0 2 2 2 0 PCI domain Sec7_N PF12783.2 EJS44069.1 - 0.21 11.0 2.1 1.2 8.5 0.5 2.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal PMP1_2 PF08114.6 EJS44070.1 - 1.3e-33 114.2 4.9 1.4e-33 114.1 3.4 1.0 1 0 0 1 1 1 1 ATPase proteolipid family DUF1049 PF06305.6 EJS44070.1 - 0.0059 16.0 1.7 0.0076 15.7 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) ACDC PF14733.1 EJS44071.1 - 0.078 13.0 0.2 7 6.8 0.0 2.6 2 0 0 2 2 2 0 AP2-coincident C-terminal YjeF_N PF03853.10 EJS44072.1 - 4e-34 117.6 0.2 8.1e-34 116.6 0.0 1.6 2 0 0 2 2 2 1 YjeF-related protein N-terminus FDF PF09532.5 EJS44072.1 - 1.3e-16 60.9 13.5 1.3e-16 60.9 9.3 2.5 3 0 0 3 3 3 1 FDF domain Arm PF00514.18 EJS44073.1 - 1.8e-72 236.9 25.4 1.5e-12 46.8 0.0 10.5 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EJS44073.1 - 1.1e-26 92.9 9.3 5.8e-07 29.6 0.0 7.4 2 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 EJS44073.1 - 1.8e-15 55.5 28.7 0.012 15.6 0.0 11.1 13 0 0 13 13 12 3 HEAT repeat HEAT_EZ PF13513.1 EJS44073.1 - 2.2e-15 56.5 16.2 0.00016 22.0 0.3 8.1 8 1 1 9 9 8 4 HEAT-like repeat Adaptin_N PF01602.15 EJS44073.1 - 3.7e-14 51.9 23.9 4.9e-08 31.7 2.2 3.1 1 1 2 3 3 3 3 Adaptin N terminal region KAP PF05804.7 EJS44073.1 - 1.4e-10 39.8 0.6 5.1e-10 37.9 0.4 1.8 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 EJS44073.1 - 1.7e-09 37.1 11.2 3e-06 26.5 2.2 4.2 3 1 2 5 5 5 3 Armadillo-like Vac14_Fab1_bd PF12755.2 EJS44073.1 - 1.3e-05 25.5 0.5 0.18 12.2 0.0 4.2 3 2 1 4 4 4 2 Vacuolar 14 Fab1-binding region V-ATPase_H_N PF03224.9 EJS44073.1 - 9.1e-05 21.7 5.8 0.0035 16.5 0.6 3.5 1 1 2 3 3 3 1 V-ATPase subunit H DUF2454 PF10521.4 EJS44073.1 - 0.00015 20.8 0.1 0.08 11.9 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2454) RIX1 PF08167.7 EJS44073.1 - 0.0012 18.5 3.0 0.006 16.2 0.3 3.0 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis V-ATPase_H_C PF11698.3 EJS44073.1 - 0.0013 18.6 1.3 0.86 9.5 0.0 4.2 3 1 2 5 5 5 1 V-ATPase subunit H DUF1981 PF09324.5 EJS44073.1 - 0.049 13.1 0.4 36 3.9 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF1981) Alpha-amylase_C PF02806.13 EJS44074.1 - 8.7e-27 93.1 0.9 7.8e-26 90.0 0.2 2.5 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EJS44074.1 - 1e-16 61.2 0.2 9e-16 58.1 0.1 2.5 2 1 0 2 2 2 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 EJS44074.1 - 1.8e-14 53.5 0.0 5.7e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.1 EJS44074.1 - 0.0057 15.1 0.0 0.011 14.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 Tenui_N PF05733.6 EJS44074.1 - 0.073 12.3 0.0 12 5.0 0.0 2.1 2 0 0 2 2 2 0 Tenuivirus/Phlebovirus nucleocapsid protein Acetyltransf_1 PF00583.19 EJS44075.1 - 6.8e-13 48.4 0.1 9.7e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EJS44075.1 - 0.00027 21.0 0.1 0.00036 20.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EJS44075.1 - 0.00029 20.5 0.0 0.00053 19.6 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EJS44075.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 EJS44075.1 - 0.0025 17.9 0.1 0.004 17.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EJS44075.1 - 0.027 14.0 0.0 0.055 13.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EJS44075.1 - 0.072 12.9 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EJS44075.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EJS44076.1 - 7.7e-11 41.2 53.1 4.3e-09 35.5 33.0 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EJS44076.1 - 0.00061 18.4 15.7 0.00061 18.4 10.9 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter Aa_trans PF01490.13 EJS44077.1 - 4.5e-96 321.8 31.6 5.1e-96 321.6 21.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NPR2 PF06218.6 EJS44078.1 - 7.3e-172 571.8 5.8 7.3e-172 571.8 4.0 1.4 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Kinesin PF00225.18 EJS44079.1 - 2.9e-95 318.7 11.2 6.3e-63 212.4 4.5 4.0 4 1 1 5 5 5 2 Kinesin motor domain DUF2937 PF11157.3 EJS44079.1 - 0.059 12.7 1.1 0.5 9.6 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Peptidase_S8 PF00082.17 EJS44080.1 - 1.1e-56 192.0 3.9 2e-56 191.2 2.7 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EJS44080.1 - 1.1e-12 48.3 0.2 1.1e-12 48.3 0.2 2.5 3 0 0 3 3 3 1 Peptidase inhibitor I9 MIP-T3 PF10243.4 EJS44080.1 - 6.5 5.0 34.7 11 4.3 24.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mitochondr_Som1 PF11093.3 EJS44081.1 - 4.7e-23 80.7 0.2 5.4e-23 80.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 PGM_PMM_I PF02878.11 EJS44082.1 - 1.4e-15 57.0 0.0 2.9e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EJS44082.1 - 4.1e-12 46.3 0.0 1.1e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EJS44082.1 - 1.8e-09 37.4 0.0 4.6e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EJS44082.1 - 0.0041 17.1 0.7 0.014 15.4 0.2 2.1 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Nup96 PF12110.3 EJS44083.1 - 0.061 12.4 0.1 0.081 12.0 0.1 1.1 1 0 0 1 1 1 0 Nuclear protein 96 CAF1C_H4-bd PF12265.3 EJS44084.1 - 4.4e-25 87.3 0.1 1.1e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EJS44084.1 - 2.2e-20 71.7 0.3 5.5e-06 26.0 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat CNH PF00780.17 EJS44084.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 CNH domain Ribosomal_L11_N PF03946.9 EJS44085.1 - 4.3e-17 61.3 0.2 8.6e-17 60.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EJS44085.1 - 3.1e-11 43.2 1.1 5.3e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain AFG1_ATPase PF03969.11 EJS44086.1 - 4e-71 239.7 0.0 2.2e-64 217.5 0.0 3.6 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EJS44086.1 - 1.2e-05 25.3 0.1 0.0057 16.6 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EJS44086.1 - 0.0018 18.3 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EJS44086.1 - 0.0037 17.4 0.0 0.0079 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 EJS44086.1 - 0.0061 16.2 0.1 0.012 15.2 0.0 1.6 1 1 0 1 1 1 1 Bacterial dnaA protein NACHT PF05729.7 EJS44086.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EJS44086.1 - 0.015 14.9 0.0 0.039 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EJS44086.1 - 0.018 15.2 0.0 0.061 13.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 EJS44086.1 - 0.031 13.9 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Mg_chelatase PF01078.16 EJS44086.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATP-synt_D PF01813.12 EJS44087.1 - 4.8e-63 212.2 4.7 6.1e-63 211.9 3.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit D RICH PF05062.7 EJS44087.1 - 0.21 11.7 5.1 0.24 11.5 1.4 2.3 2 0 0 2 2 2 0 RICH domain Ribosomal_L2_C PF03947.13 EJS44088.1 - 1.4e-50 170.4 1.5 2.5e-50 169.6 1.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EJS44088.1 - 2.4e-27 94.6 0.2 5.4e-27 93.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SRP1_TIP1 PF00660.12 EJS44089.1 - 6.6e-32 109.4 0.1 8.4e-32 109.1 0.1 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family Sedlin_N PF04628.8 EJS44090.1 - 8e-13 48.3 0.1 9.1e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FAD_binding_2 PF00890.19 EJS44091.1 - 8.5e-73 245.5 0.0 9.7e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EJS44091.1 - 2.1e-10 40.0 0.0 5.4e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EJS44091.1 - 1.7e-08 34.5 0.4 7.7e-06 25.9 0.1 2.8 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EJS44091.1 - 6.6e-08 32.4 0.0 2.4e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EJS44091.1 - 7.9e-08 31.7 0.0 2.7e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EJS44091.1 - 3.5e-07 30.5 0.0 9.5e-06 25.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EJS44091.1 - 2.3e-06 26.3 1.2 0.016 13.6 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.7 EJS44091.1 - 1e-05 24.6 0.2 0.057 12.3 0.1 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 EJS44091.1 - 6.8e-05 22.0 2.0 0.0015 17.6 0.3 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EJS44091.1 - 7.2e-05 22.6 0.0 0.00057 19.6 0.0 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EJS44091.1 - 0.00056 20.2 0.2 0.39 11.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EJS44091.1 - 0.013 14.5 0.0 4.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GMC_oxred_N PF00732.14 EJS44091.1 - 0.053 12.6 0.9 3.8 6.5 0.0 2.5 3 0 0 3 3 3 0 GMC oxidoreductase Trp_halogenase PF04820.9 EJS44091.1 - 0.066 11.8 0.0 2.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DUF903 PF06004.7 EJS44091.1 - 0.076 12.5 0.1 0.076 12.5 0.0 1.9 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF903) Beta_elim_lyase PF01212.16 EJS44092.1 - 9.3e-76 254.7 0.0 1.1e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DUF955 PF06114.8 EJS44092.1 - 0.015 15.0 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF955) DnaI_N PF07319.6 EJS44093.1 - 0.038 14.2 11.2 0.1 12.8 0.5 3.4 2 1 2 4 4 4 0 Primosomal protein DnaI N-terminus NAD_kinase PF01513.16 EJS44094.1 - 8.6e-81 270.8 0.0 1.1e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Cupin_6 PF12852.2 EJS44094.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Cupin Glyco_hydro_16 PF00722.16 EJS44095.1 - 5.1e-37 126.9 5.6 5.1e-37 126.9 3.9 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EJS44095.1 - 0.012 15.5 12.6 0.027 14.4 8.8 1.5 1 0 0 1 1 1 0 Chitin recognition protein YcgR_2 PF12945.2 EJS44095.1 - 0.079 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein YcgR DUF566 PF04484.7 EJS44095.1 - 7.9 5.8 21.7 11 5.3 15.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Cytochrom_C PF00034.16 EJS44096.1 - 1.9e-09 38.2 0.4 3.1e-09 37.5 0.3 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EJS44096.1 - 3.4e-08 33.5 2.0 5.7e-07 29.5 1.4 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EJS44096.1 - 0.004 16.6 1.0 0.0092 15.4 0.2 1.9 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 EJS44096.1 - 0.075 13.3 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrom_C1 PF02167.10 EJS44096.1 - 0.098 12.2 0.2 0.14 11.8 0.1 1.4 1 1 0 1 1 1 0 Cytochrome C1 family UBA PF00627.26 EJS44097.1 - 2.8e-25 87.4 1.5 1.2e-14 53.6 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 EJS44097.1 - 2.2e-17 62.1 0.3 5.7e-17 60.8 0.3 1.6 2 0 0 2 2 2 1 Ubiquitin family XPC-binding PF09280.6 EJS44097.1 - 6.7e-14 51.0 0.1 1.6e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 EJS44097.1 - 1.2e-07 31.3 0.1 3.1e-07 29.9 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EJS44097.1 - 6.1e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EJS44097.1 - 0.0029 17.7 0.0 0.006 16.7 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CUE PF02845.11 EJS44097.1 - 0.0052 16.2 1.5 2.6 7.6 0.0 4.4 3 2 1 4 4 4 1 CUE domain RepB PF07506.6 EJS44097.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RepB plasmid partitioning protein DUF3306 PF11748.3 EJS44097.1 - 1.5 9.5 9.9 0.15 12.6 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Anp1 PF03452.9 EJS44098.1 - 3.7e-123 409.9 1.0 2.5e-122 407.2 0.0 2.0 2 0 0 2 2 2 1 Anp1 AAR2 PF05282.6 EJS44098.1 - 0.0046 15.9 8.3 0.0072 15.3 5.7 1.2 1 0 0 1 1 1 1 AAR2 protein Suf PF05843.9 EJS44098.1 - 0.058 13.1 6.7 0.11 12.2 4.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 EJS44098.1 - 1.2 8.1 18.7 0.47 9.4 11.3 1.5 2 0 0 2 2 2 0 Fms-interacting protein BAF1_ABF1 PF04684.8 EJS44098.1 - 1.4 7.6 21.5 2 7.1 14.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF913 PF06025.7 EJS44098.1 - 5.3 5.6 6.9 7.9 5.1 4.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FLO_LFY PF01698.11 EJS44098.1 - 6.5 5.4 11.1 9.3 4.9 7.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4407 PF14362.1 EJS44098.1 - 8.4 5.2 8.7 14 4.5 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-5a PF01287.15 EJS44099.1 - 1.7e-27 95.1 0.4 2.5e-27 94.5 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 EJS44099.1 - 0.00047 19.9 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 EJS44099.1 - 0.0031 17.1 0.5 0.0061 16.2 0.4 1.5 1 0 0 1 1 1 1 KOW motif TcdB_toxin_midN PF12256.3 EJS44099.1 - 0.083 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region TgMIC1 PF11476.3 EJS44099.1 - 0.098 12.1 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 MCM PF00493.18 EJS44100.1 - 2.5e-129 430.8 0.1 3.6e-129 430.3 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EJS44100.1 - 2.8e-25 89.1 0.0 1.4e-24 86.8 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EJS44100.1 - 1.2e-07 31.1 0.0 1.5e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EJS44100.1 - 0.0042 16.6 0.4 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EJS44100.1 - 0.014 14.8 0.0 0.037 13.5 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain ORC6 PF05460.8 EJS44100.1 - 0.057 12.5 6.8 0.1 11.7 4.7 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hydrolase PF00702.21 EJS44101.1 - 5.6e-23 82.4 0.0 1.8e-22 80.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EJS44101.1 - 1.2e-21 77.7 0.1 2.3e-21 76.8 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EJS44101.1 - 2e-17 63.0 0.9 3.7e-17 62.1 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EJS44101.1 - 8.2e-07 28.8 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EJS44101.1 - 0.00087 18.9 0.3 0.0051 16.4 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EJS44101.1 - 0.039 13.2 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Phos_pyr_kin PF08543.7 EJS44102.1 - 3.8e-11 42.6 0.0 5e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EJS44102.1 - 2.5e-10 39.9 0.0 7e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase ATP-synt_C PF00137.16 EJS44103.1 - 4.6e-32 109.7 27.6 1.9e-18 66.1 7.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 EJS44103.1 - 1.5 8.4 8.5 0.41 10.2 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Ribosomal_L7Ae PF01248.21 EJS44104.1 - 1.2e-27 95.2 0.0 1.4e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EJS44104.1 - 0.014 15.2 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 PELOTA_1 PF15608.1 EJS44104.1 - 0.029 14.1 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain UCR_TM PF02921.9 EJS44105.1 - 3.6e-19 68.7 1.3 5.7e-19 68.1 0.9 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EJS44105.1 - 2.3e-17 62.3 0.1 3.8e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF2235 PF09994.4 EJS44106.1 - 9.7e-86 287.5 0.0 1.3e-85 287.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) OMPdecase PF00215.19 EJS44107.1 - 5.6e-75 251.6 0.0 6.4e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family zf-Tim10_DDP PF02953.10 EJS44108.1 - 6.3e-21 73.4 6.9 9e-21 72.9 4.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mmp37 PF09139.6 EJS44108.1 - 0.027 13.5 0.5 0.029 13.3 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 DUF1178 PF06676.6 EJS44108.1 - 0.049 13.8 0.2 0.07 13.3 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Ku_PK_bind PF08785.6 EJS44108.1 - 0.087 12.7 2.6 0.098 12.5 1.8 1.1 1 0 0 1 1 1 0 Ku C terminal domain like Pepsin-I3 PF06394.8 EJS44108.1 - 0.16 11.6 2.0 0.54 9.9 0.0 2.1 2 1 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain CARM1 PF11531.3 EJS44108.1 - 0.18 11.5 1.2 0.37 10.5 0.8 1.7 1 1 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal Vicilin_N PF04702.7 EJS44108.1 - 0.46 10.1 5.5 0.63 9.6 3.8 1.2 1 0 0 1 1 1 0 Vicilin N terminal region Iron_permease PF04120.7 EJS44109.1 - 1.2e-25 89.6 22.7 7.3e-15 54.7 0.7 5.1 5 0 0 5 5 5 4 Low affinity iron permease Exo_endo_phos PF03372.18 EJS44110.1 - 6.1e-25 88.5 0.1 8.1e-25 88.1 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNB PF00773.14 EJS44111.1 - 1.5e-69 234.8 0.1 2.8e-69 233.9 0.0 1.5 2 0 0 2 2 2 1 RNB domain DEAD PF00270.24 EJS44112.1 - 7.5e-44 149.2 0.5 3.2e-43 147.1 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS44112.1 - 4.8e-22 77.6 0.0 1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EJS44112.1 - 2.8e-21 74.8 0.3 5.5e-21 73.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EJS44112.1 - 0.0065 16.3 0.0 0.021 14.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EJS44112.1 - 0.0067 15.7 0.0 0.022 14.0 0.0 1.7 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.1 EJS44112.1 - 0.028 14.5 1.2 0.16 12.1 0.6 2.5 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 EJS44113.1 - 9.5e-52 175.7 1.4 9.5e-52 175.7 0.9 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44113.1 - 7.2e-24 84.2 0.7 2.8e-21 75.7 0.2 3.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS44113.1 - 0.008 15.1 0.6 0.82 8.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Amidase PF01425.16 EJS44114.1 - 1.4e-118 396.5 0.0 1.7e-118 396.3 0.0 1.0 1 0 0 1 1 1 1 Amidase DNA_pol_B_2 PF03175.8 EJS44114.1 - 0.012 14.3 1.0 0.079 11.6 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral DUF2406 PF10295.4 EJS44115.1 - 4.6e-26 91.1 0.4 1.1e-25 89.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Rotamase_3 PF13616.1 EJS44115.1 - 0.27 11.4 2.0 0.24 11.6 0.3 1.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain Aminotran_1_2 PF00155.16 EJS44116.1 - 3.1e-85 286.2 0.1 3.7e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_S10 PF00450.17 EJS44117.1 - 5.8e-128 427.5 0.4 7.3e-128 427.2 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EJS44117.1 - 8.2e-28 96.8 0.2 1.4e-27 96.0 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide GATase_2 PF00310.16 EJS44119.1 - 3.3e-24 85.2 0.1 2.3e-18 66.0 0.0 2.6 2 1 0 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EJS44119.1 - 1.2e-14 54.4 0.0 4e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EJS44119.1 - 6.9e-12 45.1 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 EJS44119.1 - 1.3e-11 44.2 0.0 2.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EJS44119.1 - 2.6e-06 26.3 0.0 4.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II RNA12 PF10443.4 EJS44120.1 - 1.1e-171 571.0 5.0 1.3e-170 567.6 1.9 2.1 2 0 0 2 2 2 2 RNA12 protein RRM_1 PF00076.17 EJS44120.1 - 4.4e-08 32.6 0.0 9.3e-08 31.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 EJS44120.1 - 9.6e-05 22.1 0.1 0.00075 19.2 0.1 2.3 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EJS44120.1 - 0.00053 19.8 0.4 0.0031 17.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EJS44120.1 - 0.0035 17.4 0.1 0.19 11.8 0.0 3.4 2 1 1 3 3 3 1 AAA domain RRN3 PF05327.6 EJS44120.1 - 0.022 12.8 6.0 0.034 12.2 4.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cytochrom_B559a PF00284.15 EJS44120.1 - 0.13 11.7 0.1 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit ADH_N PF08240.7 EJS44121.1 - 8.3e-31 105.9 0.2 2.8e-30 104.2 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EJS44121.1 - 8.1e-30 103.0 2.0 1.2e-29 102.5 1.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EJS44121.1 - 1.6e-05 25.7 0.1 5.2e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase UCH PF00443.24 EJS44122.1 - 1.7e-52 178.1 4.5 3.2e-52 177.3 3.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EJS44122.1 - 2.1e-47 161.3 3.9 2.1e-47 161.3 2.7 2.9 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EJS44122.1 - 5.3e-34 117.9 1.5 5.6e-34 117.9 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EJS44122.1 - 1.1e-29 103.4 12.8 3.3e-29 101.8 0.0 4.4 4 2 1 5 5 5 2 ICP0-binding domain of Ubiquitin-specific protease 7 MATH PF00917.21 EJS44122.1 - 4e-14 52.8 0.1 1.9e-13 50.7 0.0 2.3 2 0 0 2 2 2 1 MATH domain UN_NPL4 PF11543.3 EJS44122.1 - 0.91 9.8 3.9 0.97 9.7 0.2 3.1 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Glucan_synthase PF02364.10 EJS44123.1 - 0 1410.4 2.1 0 1410.4 1.4 2.1 1 1 1 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EJS44123.1 - 5.8e-39 132.6 0.1 1.5e-38 131.3 0.1 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 EJS44124.1 - 7.6e-147 488.3 12.7 7.6e-147 488.3 8.8 1.4 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.8 EJS44124.1 - 2.3e-28 98.5 4.6 7.5e-28 96.8 3.2 2.0 1 0 0 1 1 1 1 X8 domain DUF3633 PF12315.3 EJS44124.1 - 1.2 8.3 4.4 2.5 7.3 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) HEAT PF02985.17 EJS44125.1 - 8e-20 69.0 4.7 0.014 15.3 0.0 10.7 11 0 0 11 11 11 5 HEAT repeat HEAT_EZ PF13513.1 EJS44125.1 - 2e-18 66.3 14.7 1.8e-06 28.2 0.0 11.2 10 1 3 13 13 13 4 HEAT-like repeat HEAT_2 PF13646.1 EJS44125.1 - 2.9e-18 65.9 2.3 8.3e-08 32.4 0.0 6.9 6 2 3 9 9 9 5 HEAT repeats MMS19_C PF12460.3 EJS44125.1 - 6.4e-08 31.7 5.9 0.0022 16.8 0.6 3.8 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 EJS44125.1 - 4.3e-07 29.5 1.2 0.00081 18.8 0.2 3.9 5 0 0 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EJS44125.1 - 4.9e-06 26.8 1.1 0.42 11.0 0.0 6.7 4 2 3 8 8 8 1 Vacuolar 14 Fab1-binding region ParcG PF10274.4 EJS44125.1 - 0.0031 17.4 0.1 0.32 10.8 0.0 3.4 2 1 0 2 2 2 1 Parkin co-regulated protein DNA_alkylation PF08713.6 EJS44125.1 - 0.033 13.7 0.0 0.11 11.9 0.0 2.0 1 0 0 1 1 1 0 DNA alkylation repair enzyme Arm PF00514.18 EJS44125.1 - 0.041 13.7 10.5 2.2 8.2 0.0 5.8 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat eIF-3c_N PF05470.7 EJS44126.1 - 2.3e-193 643.5 28.0 2.5e-151 504.7 5.4 2.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EJS44126.1 - 2e-13 50.5 3.1 2.7e-13 50.1 0.1 2.8 2 2 0 2 2 2 1 PCI domain Methyltrn_RNA_3 PF02598.12 EJS44127.1 - 1.3e-80 270.8 0.0 1.6e-80 270.6 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase RasGEF_N PF00618.15 EJS44128.1 - 0.00048 20.1 2.9 0.0011 19.0 2.0 1.8 1 1 0 1 1 1 1 RasGEF N-terminal motif DUF2348 PF09807.4 EJS44128.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2348) DUF3336 PF11815.3 EJS44129.1 - 2.3e-27 95.2 0.1 4.3e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EJS44129.1 - 8.9e-09 35.5 0.0 1.6e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Proteasome PF00227.21 EJS44130.1 - 7.7e-45 152.5 0.0 9.4e-45 152.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EJS44130.1 - 8.8e-13 47.3 0.2 1.9e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.11 EJS44130.1 - 0.15 11.7 0.2 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK GFO_IDH_MocA PF01408.17 EJS44131.1 - 2.4e-26 92.5 0.2 8.4e-26 90.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EJS44131.1 - 2e-11 43.6 0.0 3.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EJS44131.1 - 0.0027 18.1 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Cyt-b5 PF00173.23 EJS44132.1 - 1.4e-21 76.1 0.3 3.3e-21 74.8 0.2 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EJS44132.1 - 1.1e-10 41.8 18.6 1.7e-10 41.2 10.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Abi PF02517.11 EJS44133.1 - 3.3e-12 46.3 6.7 3.3e-12 46.3 4.7 2.0 2 1 0 2 2 2 1 CAAX protease self-immunity Bul1_N PF04425.7 EJS44134.1 - 7.7e-162 538.8 0.6 7.7e-162 538.8 0.4 1.7 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 EJS44134.1 - 8.6e-114 379.3 15.2 8.6e-114 379.3 10.5 2.3 3 0 0 3 3 3 1 Bul1 C terminus ubiquitin PF00240.18 EJS44135.1 - 2.3e-23 81.3 0.1 3.6e-23 80.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EJS44135.1 - 6.7e-13 48.1 0.0 1e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EJS44135.1 - 3e-07 30.0 0.0 7.4e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_2 PF14560.1 EJS44135.1 - 2.1e-06 27.8 0.0 4.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EJS44135.1 - 6.7e-06 25.9 0.1 1.8e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EJS44135.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain PGM_PMM_I PF02878.11 EJS44136.1 - 1.3e-38 131.6 0.0 2.7e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EJS44136.1 - 4.6e-17 62.2 0.0 1.2e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EJS44136.1 - 3.1e-11 43.3 0.0 5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EJS44136.1 - 3.1e-07 30.2 0.0 7.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PIG-L PF02585.12 EJS44137.1 - 5.1e-20 72.2 0.0 8e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.2 EJS44138.1 - 1.9e-39 133.8 0.1 5.5e-39 132.3 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial ATPase expression TPR_14 PF13428.1 EJS44138.1 - 0.15 12.7 0.0 39 5.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Init_tRNA_PT PF04179.7 EJS44139.1 - 1.3e-158 528.5 2.0 1.5e-158 528.3 1.4 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DUF1938 PF09153.5 EJS44139.1 - 0.14 12.0 2.7 23 4.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1938) Pyridoxal_deC PF00282.14 EJS44140.1 - 1.9e-53 181.2 0.0 2.8e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain IL31 PF15209.1 EJS44140.1 - 0.036 13.6 0.3 0.1 12.2 0.1 1.9 2 0 0 2 2 2 0 Interleukin 31 PAGK PF15284.1 EJS44141.1 - 0.038 13.7 0.1 0.042 13.5 0.1 1.2 1 0 0 1 1 1 0 Phage-encoded virulence factor SR-25 PF10500.4 EJS44142.1 - 0.0055 16.2 1.9 0.0067 15.9 1.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein COX7a PF02238.10 EJS44144.1 - 0.052 13.2 0.3 0.086 12.5 0.2 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa F-box-like PF12937.2 EJS44145.1 - 0.00017 21.2 0.0 0.00046 19.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EJS44145.1 - 0.06 13.0 0.4 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 F-box domain eIF-1a PF01176.14 EJS44146.1 - 4.7e-27 93.2 0.2 6.5e-27 92.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 EJS44146.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Glyco_transf_20 PF00982.16 EJS44147.1 - 4.2e-177 589.3 2.9 4.2e-177 589.3 2.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EJS44147.1 - 2.2e-49 167.5 0.0 3.6e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase VSP PF03302.8 EJS44147.1 - 0.081 11.5 0.1 0.17 10.5 0.1 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein TatD_DNase PF01026.16 EJS44148.1 - 9.1e-44 149.5 0.0 1.1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase SAP30_Sin3_bdg PF13867.1 EJS44149.1 - 4e-14 52.2 0.2 1.6e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Secretin_N_2 PF07655.8 EJS44149.1 - 0.1 12.9 21.9 0.24 11.8 15.2 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Pex14_N PF04695.8 EJS44149.1 - 0.43 10.6 4.0 0.68 9.9 2.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CUE PF02845.11 EJS44150.1 - 5e-11 41.8 0.0 8.4e-11 41.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain Pyrophosphatase PF00719.14 EJS44151.1 - 8.2e-49 165.0 0.0 1.1e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase RRM_1 PF00076.17 EJS44152.1 - 4.4e-43 144.7 2.5 1.3e-12 47.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS44152.1 - 8e-31 105.8 1.2 1.4e-08 34.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS44152.1 - 6.8e-10 38.6 1.5 0.00022 20.9 0.1 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EJS44152.1 - 3.6e-08 33.0 0.0 0.0016 18.1 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EJS44152.1 - 1.7e-06 27.1 1.6 4.2e-06 25.9 1.1 1.8 1 0 0 1 1 1 1 Lsm interaction motif DUF4283 PF14111.1 EJS44152.1 - 0.02 14.0 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) Pribosyltran PF00156.22 EJS44153.1 - 6.5e-13 48.5 0.6 1.1e-12 47.8 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ribosomal_S17 PF00366.15 EJS44154.1 - 8e-16 57.8 0.4 8e-16 57.8 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 GDC-P PF02347.11 EJS44155.1 - 4.7e-203 674.6 0.0 4.5e-190 631.8 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.15 EJS44155.1 - 0.00025 19.4 0.0 0.00058 18.2 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EJS44155.1 - 0.00055 19.1 0.0 0.0075 15.4 0.0 2.1 2 0 0 2 2 2 1 Beta-eliminating lyase Helicase_Sgs1 PF11408.3 EJS44156.1 - 6.2e-33 112.4 0.1 1.7e-32 111.0 0.1 1.8 1 0 0 1 1 1 1 Sgs1 RecQ helicase RQC PF09382.5 EJS44156.1 - 3.2e-27 94.3 0.1 7.5e-27 93.1 0.1 1.7 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 EJS44156.1 - 2.8e-22 78.9 0.3 6.3e-21 74.6 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS44156.1 - 2.7e-21 75.2 0.0 3.4e-19 68.4 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.18 EJS44156.1 - 0.075 12.7 0.0 0.24 11.1 0.0 1.9 1 0 0 1 1 1 0 HRDC domain RabGAP-TBC PF00566.13 EJS44158.1 - 6.4e-25 87.8 1.1 6.4e-25 87.8 0.8 2.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain APG6 PF04111.7 EJS44158.1 - 0.0061 15.6 8.8 0.0061 15.6 6.1 3.1 3 1 1 4 4 4 1 Autophagy protein Apg6 Peripla_BP_2 PF01497.13 EJS44158.1 - 0.012 14.7 0.2 0.03 13.4 0.0 1.8 2 0 0 2 2 2 0 Periplasmic binding protein Nodulin PF02451.10 EJS44158.1 - 0.11 12.0 0.7 0.2 11.0 0.5 1.4 1 0 0 1 1 1 0 Nodulin Rootletin PF15035.1 EJS44158.1 - 7 6.5 18.6 1.5 8.7 8.2 2.9 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion bZIP_2 PF07716.10 EJS44158.1 - 9.7 6.1 9.3 3.2 7.6 2.5 2.7 2 0 0 2 2 2 0 Basic region leucine zipper Ribosomal_L28 PF00830.14 EJS44159.1 - 1.9e-21 75.6 1.5 4.1e-21 74.5 1.1 1.6 1 0 0 1 1 1 1 Ribosomal L28 family Glyco_hydro_63 PF03200.11 EJS44161.1 - 0.0011 16.9 1.0 0.0011 16.9 0.7 4.6 3 2 0 3 3 3 2 Mannosyl oligosaccharide glucosidase V-SNARE_C PF12352.3 EJS44162.1 - 3e-22 78.4 2.4 3e-22 78.4 1.7 2.5 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EJS44162.1 - 8.6e-20 70.6 4.9 8.6e-20 70.6 3.4 2.8 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 EJS44162.1 - 0.00069 19.2 1.7 0.00069 19.2 1.2 2.4 2 2 0 2 2 2 1 Sec20 DUF1744 PF08490.7 EJS44162.1 - 0.0032 16.0 0.5 0.037 12.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) CytochromB561_N PF09786.4 EJS44162.1 - 0.009 14.5 5.9 0.013 14.0 0.6 2.0 1 1 0 2 2 2 1 Cytochrome B561, N terminal Fusion_gly PF00523.13 EJS44162.1 - 0.0092 14.0 5.3 0.21 9.6 0.4 2.4 2 0 0 2 2 2 2 Fusion glycoprotein F0 Nsp1_C PF05064.8 EJS44162.1 - 0.017 14.7 3.0 0.017 14.7 2.1 2.9 2 2 1 3 3 3 0 Nsp1-like C-terminal region Prominin PF05478.6 EJS44162.1 - 0.037 11.5 8.1 0.061 10.8 5.6 1.3 1 1 0 1 1 1 0 Prominin T2SF PF00482.18 EJS44162.1 - 0.082 12.8 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Flu_NS2 PF00601.14 EJS44162.1 - 0.11 12.7 2.3 0.12 12.5 0.2 2.0 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) DUF3753 PF12575.3 EJS44162.1 - 0.18 11.5 3.7 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) YqjK PF13997.1 EJS44162.1 - 0.2 11.8 0.1 0.2 11.8 0.0 2.4 4 0 0 4 4 3 0 YqjK-like protein CCDC84 PF14968.1 EJS44162.1 - 0.34 10.3 2.7 0.4 10.1 1.9 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 Snapin_Pallidin PF14712.1 EJS44162.1 - 0.48 10.7 9.7 0.13 12.5 2.3 2.6 2 2 0 2 2 2 0 Snapin/Pallidin SNARE PF05739.14 EJS44162.1 - 0.68 9.6 8.8 1.4 8.6 0.5 2.6 2 1 0 2 2 2 0 SNARE domain DUF106 PF01956.11 EJS44162.1 - 0.91 9.0 3.7 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 Use1 PF09753.4 EJS44162.1 - 3.2 7.1 11.5 31 3.8 7.9 2.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF4410 PF14366.1 EJS44162.1 - 6.3 6.5 6.2 0.82 9.4 0.8 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4410) Reo_sigmaC PF04582.7 EJS44163.1 - 0.007 15.5 3.0 1.1 8.3 0.1 2.6 2 0 0 2 2 2 2 Reovirus sigma C capsid protein DUF2525 PF10733.4 EJS44163.1 - 0.045 13.5 0.2 0.14 11.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) CENP-F_leu_zip PF10473.4 EJS44163.1 - 5.5 6.8 45.4 1.2 9.0 11.6 3.9 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cyclin_N PF00134.18 EJS44164.1 - 2.4e-37 127.3 0.0 5.2e-37 126.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Rot1 PF10681.4 EJS44165.1 - 7.9e-98 326.0 0.7 9.1e-98 325.8 0.5 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal ERG2_Sigma1R PF04622.7 EJS44166.1 - 1.4e-95 318.6 1.8 1.6e-95 318.4 1.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein RNase_P_Rpp14 PF01900.14 EJS44166.1 - 0.023 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Rpp14/Pop5 family Porin_3 PF01459.17 EJS44167.1 - 1e-81 274.2 0.2 1.2e-81 274.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Inp1 PF12634.2 EJS44168.1 - 1.1e-47 161.3 0.6 1.1e-47 161.3 0.4 2.2 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 HipA_N PF07805.7 EJS44168.1 - 0.093 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 HipA-like N-terminal domain PFK PF00365.15 EJS44169.1 - 1e-166 552.9 0.2 1.1e-124 414.9 0.8 2.1 2 0 0 2 2 2 2 Phosphofructokinase Glyoxalase_2 PF12681.2 EJS44169.1 - 0.0071 16.9 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 Glyoxalase-like domain GHMP_kinases_N PF00288.21 EJS44170.1 - 5.3e-23 80.8 0.5 1.5e-22 79.4 0.4 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EJS44170.1 - 5.8e-05 23.2 0.0 0.00019 21.5 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Tubulin_3 PF14881.1 EJS44171.1 - 1.2e-23 83.5 0.1 2.1e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EJS44171.1 - 5.9e-20 71.4 0.7 5.9e-20 71.4 0.5 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EJS44171.1 - 1.4e-05 25.0 0.0 0.00032 20.5 0.0 2.2 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain DnaJ PF00226.26 EJS44173.1 - 3.6e-26 90.6 3.3 5.8e-26 90.0 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EJS44173.1 - 5.9e-15 55.0 16.3 1e-14 54.2 11.3 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EJS44173.1 - 8.3e-14 51.2 0.0 7.9e-13 48.1 0.0 2.5 3 0 0 3 3 3 1 DnaJ C terminal domain HypA PF01155.14 EJS44173.1 - 0.17 11.5 9.0 0.55 9.9 0.3 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF1924 PF09086.6 EJS44173.1 - 0.39 10.7 3.0 2.9 7.9 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) Cytochrom_C550 PF14495.1 EJS44173.1 - 1.2 8.5 3.3 8.8 5.7 0.7 2.3 2 0 0 2 2 2 0 Cytochrome c-550 domain Cytochrom_C PF00034.16 EJS44173.1 - 1.3 9.9 4.7 9.5 7.1 0.0 3.2 3 0 0 3 3 3 0 Cytochrome c Cytochrome_C7 PF14522.1 EJS44173.1 - 1.9 8.1 14.6 30 4.3 4.0 2.7 1 1 1 2 2 2 0 Cytochrome c7 Glyco_hydro_72 PF03198.9 EJS44174.1 - 1.9e-129 431.1 2.8 2.7e-129 430.6 1.9 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EJS44174.1 - 0.00013 20.9 0.0 0.00028 19.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EJS44174.1 - 0.006 15.8 0.0 0.025 13.7 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Apt1 PF10351.4 EJS44174.1 - 0.45 9.3 5.3 0.69 8.7 3.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.4 EJS44174.1 - 1.1 7.7 6.0 1.6 7.2 4.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GMP_synt_C PF00958.17 EJS44175.1 - 7.1e-41 137.8 0.0 1.7e-40 136.5 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EJS44175.1 - 3.1e-40 137.6 0.0 5.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EJS44175.1 - 2.4e-09 36.4 0.1 1.2e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EJS44175.1 - 5.1e-07 29.3 0.0 1.8e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EJS44175.1 - 0.0068 15.7 0.0 0.22 10.7 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 EJS44175.1 - 0.0081 15.2 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase ThiI PF02568.9 EJS44175.1 - 0.0099 15.3 0.0 0.024 14.0 0.0 1.6 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 EJS44175.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.11 EJS44175.1 - 0.065 11.7 0.1 0.14 10.7 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase Asn_synthase PF00733.16 EJS44175.1 - 0.19 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase TRAPPC10 PF12584.3 EJS44176.1 - 5.5e-13 48.6 0.0 1.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 GHMP_kinases_N PF00288.21 EJS44177.1 - 4.7e-14 52.1 0.1 1.1e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EJS44177.1 - 0.0016 18.6 0.0 0.0036 17.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Uteroglobin PF01099.12 EJS44177.1 - 0.048 13.4 0.0 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 Uteroglobin family MFS_1 PF07690.11 EJS44178.1 - 4.5e-12 45.3 26.3 5.1e-07 28.7 4.6 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily UCH PF00443.24 EJS44179.1 - 3.1e-64 216.6 5.0 3.1e-64 216.6 3.5 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EJS44179.1 - 1.4e-31 110.0 4.1 2.1e-31 109.4 2.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EJS44179.1 - 2.9e-11 43.3 9.8 2.9e-11 43.3 6.8 3.0 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Mre11_DNA_bind PF04152.9 EJS44180.1 - 1.7e-53 181.0 1.4 1.7e-53 181.0 1.0 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EJS44180.1 - 2.7e-26 92.1 2.7 4.3e-26 91.5 1.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EJS44180.1 - 0.00037 20.3 0.0 0.0012 18.6 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain adh_short PF00106.20 EJS44181.1 - 2.9e-31 108.6 0.0 3.9e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EJS44181.1 - 2.8e-14 53.4 0.1 3.4e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EJS44181.1 - 4.7e-10 39.4 0.0 6.1e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EJS44181.1 - 0.0037 17.0 0.2 0.0076 16.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EJS44181.1 - 0.021 13.9 0.0 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) UBA_4 PF14555.1 EJS44181.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DinI PF06183.8 EJS44181.1 - 0.13 12.2 0.1 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 DinI-like family TAFII55_N PF04658.8 EJS44182.1 - 6.6e-58 194.7 0.3 6.6e-58 194.7 0.2 2.6 2 1 0 2 2 2 1 TAFII55 protein conserved region Herpes_gE PF02480.11 EJS44182.1 - 4.2 5.5 7.0 12 3.9 4.9 1.7 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RrnaAD PF00398.15 EJS44183.1 - 6.3e-77 258.1 0.0 7.2e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase S1 PF00575.18 EJS44184.1 - 3.4e-57 190.4 40.8 5.3e-14 52.0 0.6 11.7 12 1 0 12 12 12 9 S1 RNA binding domain TPR_19 PF14559.1 EJS44184.1 - 8.9e-07 29.1 0.0 0.28 11.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 EJS44184.1 - 2.1e-06 27.6 3.7 0.00064 19.5 0.0 4.9 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EJS44184.1 - 4.7e-05 23.6 0.2 0.43 11.3 0.0 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EJS44184.1 - 7.6e-05 23.2 0.0 0.91 10.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat SDA1 PF05285.7 EJS44184.1 - 0.0023 17.2 25.7 0.14 11.4 7.9 2.8 2 0 0 2 2 2 2 SDA1 TPR_15 PF13429.1 EJS44184.1 - 0.062 12.3 2.0 5.3 6.0 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat VPS11_C PF12451.3 EJS44185.1 - 1.3e-12 47.3 0.1 4.2e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.1 EJS44185.1 - 0.0001 22.2 6.3 0.0003 20.7 4.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EJS44185.1 - 0.00055 19.7 5.7 0.00055 19.7 3.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EJS44185.1 - 0.0012 18.8 3.2 0.0034 17.4 2.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EJS44185.1 - 0.0032 17.2 1.6 0.0066 16.2 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EJS44185.1 - 0.0036 16.9 8.8 0.0066 16.1 4.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EJS44185.1 - 0.0096 15.5 7.4 0.029 14.0 5.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EJS44185.1 - 0.0097 15.5 4.8 0.0097 15.5 3.3 2.1 2 0 0 2 2 2 1 PHD-finger DUF2937 PF11157.3 EJS44185.1 - 0.01 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Pep3_Vps18 PF05131.9 EJS44185.1 - 0.048 13.1 1.1 0.64 9.4 0.0 3.0 3 0 0 3 3 3 0 Pep3/Vps18/deep orange family zf-C3HC4_3 PF13920.1 EJS44185.1 - 0.05 13.2 7.1 0.012 15.2 2.6 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EJS44185.1 - 0.056 13.1 2.1 0.2 11.3 1.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EJS44185.1 - 0.058 13.2 9.3 0.037 13.8 4.4 2.4 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EJS44185.1 - 0.13 12.2 2.6 0.35 10.8 1.8 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EJS44185.1 - 0.37 10.5 3.9 0.17 11.6 0.8 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 SWIB PF02201.13 EJS44187.1 - 2e-29 101.0 0.1 4e-29 100.1 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EJS44187.1 - 6.1e-10 38.7 0.1 2.5e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 DEK C terminal domain RNase_H PF00075.19 EJS44188.1 - 8.7e-29 100.5 0.0 1.6e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 EJS44188.1 - 2e-21 75.6 5.0 3.1e-16 59.1 1.0 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RVT_3 PF13456.1 EJS44188.1 - 0.011 15.5 0.1 1.2 8.9 0.0 3.2 3 0 0 3 3 3 0 Reverse transcriptase-like LRR_6 PF13516.1 EJS44189.1 - 3.7e-10 38.7 8.6 0.21 11.7 0.0 8.4 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.2 EJS44189.1 - 3.1e-08 33.0 12.1 0.084 12.5 0.2 6.1 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EJS44189.1 - 4.4e-06 25.9 8.3 17 5.9 0.0 7.6 7 1 1 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.1 EJS44189.1 - 1.6e-05 24.5 13.2 0.56 9.9 0.8 5.5 4 1 1 5 5 5 3 Leucine rich repeat LRR_7 PF13504.1 EJS44189.1 - 1.3 9.5 9.8 74 4.2 0.0 6.3 7 0 0 7 7 7 0 Leucine rich repeat ChAPs PF09295.5 EJS44190.1 - 9.3e-173 574.5 4.1 1.2e-172 574.1 2.8 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.1 EJS44190.1 - 0.03 14.0 0.2 1.6 8.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EJS44190.1 - 0.039 13.5 0.4 0.73 9.5 0.1 2.4 2 0 0 2 2 2 0 TPR repeat Glyco_hydro_76 PF03663.9 EJS44191.1 - 2.6e-148 494.3 17.1 3.3e-148 493.9 11.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF3910 PF13049.1 EJS44191.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) DUF382 PF04037.8 EJS44192.1 - 2.7e-52 175.9 0.0 8.8e-52 174.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EJS44192.1 - 6.9e-21 73.3 1.3 1.2e-20 72.6 0.9 1.4 1 0 0 1 1 1 1 PSP Syntaxin_2 PF14523.1 EJS44192.1 - 0.0026 17.7 2.9 0.0026 17.7 2.0 2.2 2 0 0 2 2 2 1 Syntaxin-like protein PAS_10 PF13596.1 EJS44192.1 - 0.0067 16.6 0.6 0.015 15.5 0.4 1.6 1 0 0 1 1 1 1 PAS domain Cation_efflux PF01545.16 EJS44193.1 - 2.4e-81 272.9 6.7 3.3e-81 272.4 4.6 1.1 1 0 0 1 1 1 1 Cation efflux family TcpE PF12648.2 EJS44193.1 - 6.5 6.9 5.9 8.8 6.5 0.1 2.6 2 1 1 3 3 3 0 TcpE family SUN PF03856.8 EJS44194.1 - 3.2e-80 269.0 21.4 4.1e-80 268.6 14.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF333 PF03891.10 EJS44194.1 - 0.034 13.9 2.6 0.071 12.9 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF333) zf-RING_2 PF13639.1 EJS44195.1 - 2.9e-08 33.3 6.7 6e-08 32.3 4.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EJS44195.1 - 3.9e-07 30.0 3.7 1e-06 28.7 2.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EJS44195.1 - 1.5e-05 24.8 4.3 4.2e-05 23.4 3.0 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EJS44195.1 - 0.00045 19.9 1.7 0.00097 18.9 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EJS44195.1 - 0.012 15.1 7.7 0.029 14.0 5.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EJS44195.1 - 0.03 14.3 6.2 0.069 13.2 4.3 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 EJS44195.1 - 0.069 13.1 8.1 0.18 11.8 5.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EJS44195.1 - 0.073 12.6 5.6 0.5 9.9 0.6 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EJS44195.1 - 0.17 11.5 6.4 3.1 7.5 4.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EJS44195.1 - 0.25 11.3 6.4 0.56 10.2 4.4 1.7 1 0 0 1 1 1 0 RING-like domain zf-UDP PF14569.1 EJS44195.1 - 0.35 10.6 2.3 9.5 6.0 0.2 2.5 1 1 1 2 2 2 0 Zinc-binding RING-finger C1_1 PF00130.17 EJS44195.1 - 2.3 8.0 5.3 5.4 6.8 3.7 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EJS44195.1 - 5.7 6.7 6.0 11 5.7 4.2 1.5 1 0 0 1 1 1 0 PHD-finger Inhibitor_I34 PF10466.4 EJS44196.1 - 4.8e-32 109.8 12.8 5.2e-32 109.7 8.9 1.0 1 0 0 1 1 1 1 Saccharopepsin inhibitor I34 HMG_box_2 PF09011.5 EJS44196.1 - 2.5 8.5 6.0 24 5.3 3.6 2.2 1 1 1 2 2 2 0 HMG-box domain ARID PF01388.16 EJS44198.1 - 1.3e-25 89.0 0.2 8e-24 83.3 0.0 3.8 4 0 0 4 4 4 1 ARID/BRIGHT DNA binding domain JmjC PF02373.17 EJS44198.1 - 2e-08 34.4 0.0 0.00057 20.1 0.0 2.7 2 0 0 2 2 2 2 JmjC domain, hydroxylase PHD PF00628.24 EJS44198.1 - 1.9e-07 30.6 5.8 3.7e-07 29.7 4.0 1.5 1 0 0 1 1 1 1 PHD-finger PLU-1 PF08429.6 EJS44198.1 - 0.00028 19.8 0.4 0.00076 18.4 0.1 1.8 2 0 0 2 2 2 1 PLU-1-like protein C1_1 PF00130.17 EJS44198.1 - 1.3 8.7 6.9 3.4 7.4 4.8 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MoCF_biosynth PF00994.19 EJS44199.1 - 4.9e-37 126.5 0.0 1.2e-36 125.3 0.0 1.6 2 0 0 2 2 2 1 Probable molybdopterin binding domain Rot1 PF10681.4 EJS44200.1 - 0.33 10.2 6.2 0.062 12.6 0.2 2.5 2 0 0 2 2 2 0 Chaperone for protein-folding within the ER, fungal mRNA_triPase PF02940.10 EJS44201.1 - 4.5e-41 140.9 4.4 5.8e-41 140.5 3.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain SICA_beta PF12878.2 EJS44201.1 - 0.086 12.6 2.3 0.24 11.2 1.6 1.8 1 1 0 1 1 1 0 SICA extracellular beta domain SNARE PF05739.14 EJS44202.1 - 9.6e-16 57.2 7.2 9.6e-16 57.2 5.0 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EJS44202.1 - 4.6e-05 23.5 8.8 4.6e-05 23.5 6.1 2.6 1 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 EJS44202.1 - 0.00026 20.5 2.1 0.00026 20.5 1.4 2.0 2 0 0 2 2 2 1 Synaptobrevin T2SF PF00482.18 EJS44202.1 - 0.0054 16.6 0.0 0.022 14.6 0.0 2.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Rifin_STEVOR PF02009.11 EJS44202.1 - 0.007 16.0 9.8 0.033 13.8 5.7 2.2 1 1 1 2 2 2 1 Rifin/stevor family DUF4094 PF13334.1 EJS44202.1 - 0.059 13.7 0.3 0.059 13.7 0.2 3.7 2 1 3 5 5 4 0 Domain of unknown function (DUF4094) Orthopox_B11R PF07033.6 EJS44202.1 - 0.086 12.3 2.9 4.1 6.9 0.1 2.6 2 0 0 2 2 2 0 Orthopoxvirus B11R protein DUF3753 PF12575.3 EJS44202.1 - 0.14 12.0 1.9 0.61 9.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Shisa PF13908.1 EJS44202.1 - 0.15 12.2 1.1 0.36 10.9 0.8 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2562 PF10814.3 EJS44202.1 - 0.98 9.3 5.5 0.57 10.1 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2562) PTA_PTB PF01515.14 EJS44202.1 - 1.4 7.9 11.3 0.071 12.1 3.1 2.1 2 1 1 3 3 3 0 Phosphate acetyl/butaryl transferase DUF3708 PF12501.3 EJS44202.1 - 1.4 8.7 6.1 4 7.2 1.2 2.6 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter GP41 PF00517.12 EJS44202.1 - 7.4 6.0 11.2 0.61 9.6 0.1 3.4 2 2 1 3 3 3 0 Retroviral envelope protein DUF912 PF06024.7 EJS44202.1 - 9 6.4 9.7 0.27 11.3 0.3 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pox_A12 PF04651.8 EJS44202.1 - 9.4 6.3 9.9 5.6 7.0 3.8 2.7 2 1 0 2 2 2 0 Poxvirus A12 protein DUF2435 PF10363.4 EJS44203.1 - 1.9e-30 104.5 5.9 9.5e-30 102.3 0.1 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EJS44203.1 - 6.6e-08 31.8 3.1 2.3e-07 30.1 2.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DnaJ PF00226.26 EJS44205.1 - 7.4e-27 92.8 1.3 1.2e-26 92.1 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain DUF633 PF04816.7 EJS44205.1 - 0.11 11.8 0.2 0.16 11.2 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) E1-E2_ATPase PF00122.15 EJS44206.1 - 1.4e-18 66.7 0.1 4.5e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EJS44206.1 - 1.2e-15 58.5 0.7 5e-12 46.6 0.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EJS44206.1 - 4.7e-13 49.7 0.1 1.2e-11 45.1 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EJS44206.1 - 1e-11 44.6 0.0 3.7e-11 42.8 0.0 2.1 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EJS44206.1 - 0.0037 16.8 0.1 0.0037 16.8 0.1 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase FerB PF08150.7 EJS44206.1 - 0.082 12.9 0.0 3 7.9 0.0 2.7 2 0 0 2 2 2 0 FerB (NUC096) domain Vezatin PF12632.2 EJS44207.1 - 2.8e-31 108.5 18.6 5.2e-31 107.6 12.9 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Sporozoite_P67 PF05642.6 EJS44207.1 - 0.0022 15.9 4.7 0.068 11.0 1.0 2.1 2 0 0 2 2 2 2 Sporozoite P67 surface antigen LisH PF08513.6 EJS44208.1 - 5.1e-07 29.2 1.4 1.1e-06 28.2 1.0 1.6 1 0 0 1 1 1 1 LisH Trypan_PARP PF05887.6 EJS44208.1 - 0.0085 15.9 15.7 0.0085 15.9 10.9 2.3 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) LNS2 PF08235.8 EJS44209.1 - 7.8e-74 246.4 0.0 1.4e-73 245.6 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EJS44209.1 - 9.3e-46 154.0 0.0 3.8e-45 152.0 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region AF1Q PF15017.1 EJS44209.1 - 0.0053 16.6 0.1 0.0053 16.6 0.0 3.1 3 0 0 3 3 3 1 Drug resistance and apoptosis regulator Aldedh PF00171.17 EJS44210.1 - 9.1e-169 561.6 0.0 1e-168 561.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EJS44210.1 - 0.00045 19.0 0.2 0.0018 17.0 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF3294 PF07957.6 EJS44210.1 - 0.099 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Aldedh PF00171.17 EJS44211.1 - 6.2e-169 562.2 0.0 7e-169 562.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EJS44211.1 - 0.004 15.9 0.2 0.016 13.9 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EJS44211.1 - 0.13 11.4 0.0 0.44 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SPRY PF00622.23 EJS44212.1 - 2.2e-13 50.3 0.1 7.4e-13 48.6 0.1 2.0 1 0 0 1 1 1 1 SPRY domain COPI_assoc PF08507.5 EJS44213.1 - 1e-39 135.3 6.0 1.1e-39 135.2 4.2 1.0 1 0 0 1 1 1 1 COPI associated protein Grp1_Fun34_YaaH PF01184.14 EJS44213.1 - 0.54 9.5 8.9 0.032 13.5 2.6 1.6 2 0 0 2 2 2 0 GPR1/FUN34/yaaH family Ste5_C PF12194.3 EJS44214.1 - 1.3e-82 276.0 2.2 1.3e-82 276.0 1.5 1.7 2 0 0 2 2 2 1 Protein kinase Fus3-binding Ste5 PF11610.3 EJS44214.1 - 6.9e-16 57.4 1.1 1.3e-15 56.5 0.8 1.5 1 0 0 1 1 1 1 Scaffold protein Ste5-Fus5 binding region zf-RING_2 PF13639.1 EJS44214.1 - 1.7e-05 24.5 2.3 3.8e-05 23.4 1.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EJS44214.1 - 0.2 11.7 2.0 0.67 10.0 1.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RVT_3 PF13456.1 EJS44214.1 - 0.2 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Serinc PF03348.10 EJS44215.1 - 3.1e-155 517.1 18.1 3.7e-155 516.8 12.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Actin PF00022.14 EJS44216.1 - 3.1e-09 35.7 0.0 3e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Actin EMP70 PF02990.11 EJS44217.1 - 3.5e-208 692.3 12.3 5.4e-208 691.6 8.6 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 Aminotran_1_2 PF00155.16 EJS44219.1 - 9e-37 126.8 0.0 1.3e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EJS44219.1 - 0.043 12.9 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Ribosomal_L34 PF00468.12 EJS44220.1 - 2.6e-19 68.5 5.1 2.6e-19 68.5 3.5 1.5 1 1 0 1 1 1 1 Ribosomal protein L34 Ribosomal_L1 PF00687.16 EJS44221.1 - 5.3e-21 74.9 0.2 6.6e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TPP_enzyme_N PF02776.13 EJS44223.1 - 1.3e-60 203.7 0.1 1.1e-58 197.4 0.1 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EJS44223.1 - 5.4e-52 175.4 0.0 5.4e-51 172.1 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EJS44223.1 - 6.3e-35 119.9 1.2 1.3e-34 118.8 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EJS44223.1 - 0.078 12.4 0.1 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Indigoidine_A PF04227.7 EJS44223.1 - 0.081 12.1 0.8 9.6 5.3 0.0 3.1 3 1 1 4 4 4 0 Indigoidine synthase A like protein Myosin_head PF00063.16 EJS44224.1 - 2.1e-224 746.5 8.7 3.3e-224 745.9 6.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EJS44224.1 - 2.4e-52 177.1 0.7 2.6e-51 173.7 0.1 2.3 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 EJS44224.1 - 3.8e-12 45.3 0.0 8.5e-12 44.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EJS44224.1 - 4.2e-08 32.6 0.1 1.1e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EJS44224.1 - 5.7e-07 28.9 0.0 1.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EJS44224.1 - 0.0063 16.6 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EJS44224.1 - 0.01 14.9 0.0 0.031 13.3 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 EJS44224.1 - 0.01 15.1 0.1 3.2 7.0 0.0 2.8 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain SH3_3 PF08239.6 EJS44224.1 - 0.052 13.7 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain AAA_17 PF13207.1 EJS44224.1 - 0.054 14.3 0.0 0.24 12.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EJS44224.1 - 0.054 13.2 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain AAA_16 PF13191.1 EJS44224.1 - 0.06 13.3 0.0 0.24 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EJS44224.1 - 0.06 12.9 0.1 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 EJS44224.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IQ PF00612.22 EJS44224.1 - 1.1 9.0 14.5 1.8 8.3 4.3 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif Mur_ligase_M PF08245.7 EJS44225.1 - 3.1e-06 27.3 0.0 5.8e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain DUF159 PF02586.9 EJS44226.1 - 3.7e-54 183.4 0.9 5.7e-54 182.8 0.6 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Spc24 PF08286.6 EJS44227.1 - 2.4e-25 88.5 2.7 2.4e-25 88.5 1.9 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 GrpE PF01025.14 EJS44227.1 - 0.086 12.3 3.4 0.12 11.9 2.4 1.3 1 0 0 1 1 1 0 GrpE APG6 PF04111.7 EJS44227.1 - 0.25 10.3 5.4 0.26 10.2 3.5 1.2 1 1 0 1 1 1 0 Autophagy protein Apg6 Erp_C PF06780.6 EJS44227.1 - 0.33 10.7 11.1 0.52 10.1 2.9 2.3 1 1 1 2 2 2 0 Erp protein C-terminus Sdh_cyt PF01127.17 EJS44228.1 - 5.8e-25 87.4 2.8 7.5e-25 87.1 0.9 1.7 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-C3HC4_3 PF13920.1 EJS44229.1 - 6.7e-07 28.8 10.9 1.3e-06 27.9 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AICARFT_IMPCHas PF01808.13 EJS44230.1 - 5.6e-120 400.1 0.0 7.4e-120 399.7 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EJS44230.1 - 6.6e-25 86.8 0.3 1.3e-24 85.8 0.0 1.7 2 0 0 2 2 2 1 MGS-like domain Ribosomal_L15e PF00827.12 EJS44231.1 - 2.1e-90 301.3 14.0 2.4e-90 301.1 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 Pkr1 PF08636.5 EJS44232.1 - 9.8e-32 108.8 10.4 1.2e-31 108.5 7.2 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF1772 PF08592.6 EJS44232.1 - 0.0099 15.6 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Acyltransferase PF01553.16 EJS44232.1 - 0.067 12.6 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase MOZ_SAS PF01853.13 EJS44235.1 - 4.5e-66 221.7 2.9 5.8e-66 221.3 2.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family HA2 PF04408.18 EJS44236.1 - 3.6e-24 84.7 0.0 1.6e-23 82.6 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EJS44236.1 - 3.9e-17 62.1 0.0 1e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EJS44236.1 - 3.1e-13 49.3 0.0 3e-12 46.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EJS44236.1 - 2.1e-07 30.5 0.0 5.4e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EJS44236.1 - 2.9e-06 27.4 0.6 0.00014 22.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EJS44236.1 - 0.0011 18.1 2.7 0.0094 15.0 0.0 2.7 3 0 0 3 3 3 1 KaiC T2SE PF00437.15 EJS44236.1 - 0.016 14.0 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EJS44236.1 - 0.017 14.3 0.1 0.14 11.3 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein HTH_37 PF13744.1 EJS44236.1 - 0.033 13.9 5.0 0.066 13.0 0.5 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain HAD_2 PF13419.1 EJS44238.1 - 8.5e-16 58.6 0.0 1.5e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EJS44238.1 - 8.1e-09 35.0 0.0 1.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EJS44238.1 - 0.00062 20.2 0.0 0.002 18.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Abhydro_lipase PF04083.11 EJS44238.1 - 0.048 13.0 0.1 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region WD40 PF00400.27 EJS44239.1 - 1.1e-18 66.3 9.6 5.7e-07 29.1 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EJS44239.1 - 2.6e-18 65.6 0.1 6.3e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ELH PF02323.10 EJS44239.1 - 0.00023 20.4 2.9 0.038 13.1 0.2 2.2 2 0 0 2 2 2 2 Egg-laying hormone precursor DUF4057 PF13266.1 EJS44239.1 - 0.063 12.7 0.5 0.11 11.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) PRCC PF10253.4 EJS44239.1 - 0.14 12.8 2.9 0.13 12.9 0.5 2.0 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting CLTH PF10607.4 EJS44241.1 - 1.8e-20 73.0 8.7 1.8e-20 73.0 6.0 2.2 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Met_synt_B12 PF02965.12 EJS44241.1 - 0.057 12.6 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain GATA PF00320.22 EJS44242.1 - 3.7e-16 58.1 3.4 8.9e-16 56.9 2.4 1.7 1 0 0 1 1 1 1 GATA zinc finger DRMBL PF07522.9 EJS44243.1 - 3.5e-24 84.9 0.2 4e-23 81.5 0.0 2.3 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EJS44243.1 - 3.2e-06 26.8 0.2 7.5e-06 25.6 0.1 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Arf PF00025.16 EJS44244.1 - 3.9e-54 182.5 0.2 4.4e-54 182.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EJS44244.1 - 1.9e-12 46.6 4.3 1.7e-07 30.2 0.8 2.7 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EJS44244.1 - 3.1e-09 36.4 0.0 3.7e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EJS44244.1 - 9.3e-09 34.7 0.0 1.1e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EJS44244.1 - 1.5e-07 31.0 0.0 2.7e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EJS44244.1 - 6.9e-07 29.2 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EJS44244.1 - 3.4e-06 26.3 0.0 4.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EJS44244.1 - 1.3e-05 24.5 0.1 0.00012 21.3 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EJS44244.1 - 6.1e-05 23.4 0.0 8.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EJS44244.1 - 0.0057 15.4 0.0 0.13 11.0 0.0 2.0 2 0 0 2 2 2 1 ArgK protein cobW PF02492.14 EJS44244.1 - 0.006 16.0 0.1 0.48 9.8 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EJS44244.1 - 0.025 13.7 0.1 0.1 11.7 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EJS44244.1 - 0.085 12.8 0.0 0.15 11.9 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 EJS44245.1 - 6.7e-63 212.2 0.0 7.9e-63 212.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44245.1 - 1.6e-26 92.9 0.0 2.2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EJS44245.1 - 0.002 17.9 0.0 0.012 15.3 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EJS44245.1 - 0.0081 15.7 0.4 0.015 14.8 0.3 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase LMBR1 PF04791.11 EJS44246.1 - 0.58 8.6 3.6 0.66 8.4 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pyr_redox_2 PF07992.9 EJS44247.1 - 2.5e-26 92.7 0.0 2.9e-16 59.9 0.0 3.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EJS44247.1 - 2e-13 50.5 0.0 2.5e-12 47.0 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EJS44247.1 - 3.2e-06 27.3 0.1 0.01 15.8 0.0 3.6 2 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase UVR PF02151.14 EJS44247.1 - 0.067 12.7 0.2 3.3 7.3 0.0 2.7 2 0 0 2 2 2 0 UvrB/uvrC motif NAD_binding_9 PF13454.1 EJS44247.1 - 0.068 12.9 0.3 28 4.4 0.0 3.8 3 1 1 4 4 4 0 FAD-NAD(P)-binding WD40 PF00400.27 EJS44248.1 - 5.1e-32 108.5 6.5 6.6e-10 38.4 0.4 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EJS44248.1 - 2.2e-07 30.7 0.1 0.039 13.6 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EJS44248.1 - 0.029 13.1 1.3 0.26 10.0 0.1 2.4 2 1 1 3 3 3 0 Nup133 N terminal like Cytochrom_D1 PF02239.11 EJS44248.1 - 0.044 12.0 0.0 0.1 10.8 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain Tic20 PF09685.5 EJS44249.1 - 2.3 8.2 11.3 3.2 7.7 7.8 1.2 1 0 0 1 1 1 0 Tic20-like protein DUF485 PF04341.7 EJS44249.1 - 9.5 6.0 8.3 13 5.5 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Ribophorin_II PF05817.9 EJS44250.1 - 1.8e-10 39.6 1.4 2.2e-10 39.4 1.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF2140 PF09911.4 EJS44250.1 - 0.0053 15.9 0.0 0.012 14.7 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2140) Abhydrolase_9_N PF15420.1 EJS44250.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF2975 PF11188.3 EJS44250.1 - 1.8 8.3 6.5 0.53 10.0 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Peptidase_S24 PF00717.18 EJS44251.1 - 4.6e-06 26.1 0.0 1.2e-05 24.7 0.0 1.7 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 EJS44251.1 - 0.001 18.6 0.0 0.0071 15.8 0.0 2.0 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 ADH_zinc_N_2 PF13602.1 EJS44252.1 - 4.7e-12 46.8 0.0 1.2e-11 45.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EJS44252.1 - 3.1e-07 29.9 0.0 1.2e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EJS44252.1 - 1.3e-05 24.8 0.2 2.9e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.3 EJS44252.1 - 0.00017 20.8 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Semialdhyde_dh PF01118.19 EJS44252.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Nup35_RRM PF05172.8 EJS44253.1 - 4.6e-37 125.8 0.0 1e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EJS44253.1 - 0.00022 20.9 0.0 0.00054 19.6 0.0 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PNK3P PF08645.6 EJS44254.1 - 7.3e-47 158.7 0.7 8.5e-47 158.5 0.5 1.0 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Ribosomal_S8 PF00410.14 EJS44256.1 - 1.8e-19 69.8 0.0 2.1e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 E1-E2_ATPase PF00122.15 EJS44257.1 - 1.1e-65 220.8 5.2 2.2e-65 219.9 3.6 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EJS44257.1 - 2e-33 115.4 0.4 2e-33 115.4 0.3 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EJS44257.1 - 3e-26 93.1 0.0 2e-25 90.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EJS44257.1 - 7e-18 64.3 0.0 1.4e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EJS44257.1 - 3.3e-16 60.0 0.0 9.6e-16 58.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EJS44257.1 - 5.6e-15 54.5 0.0 1.9e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EJS44257.1 - 0.0025 17.4 0.6 0.0025 17.4 0.4 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ribosomal_S10 PF00338.17 EJS44258.1 - 2e-28 98.0 0.0 3.4e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-H2C2_2 PF13465.1 EJS44259.1 - 2.3e-05 24.4 5.3 2.3e-05 24.4 3.7 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EJS44259.1 - 0.00022 21.3 15.3 0.11 12.8 6.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EJS44259.1 - 0.0017 18.5 0.8 0.0017 18.5 0.6 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type Coprogen_oxidas PF01218.13 EJS44260.1 - 1.4e-132 440.7 0.0 1.6e-132 440.5 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TFIIS_C PF01096.13 EJS44261.1 - 2.7e-22 78.0 2.2 2.7e-22 78.0 1.5 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EJS44261.1 - 2.5e-17 62.2 1.5 6.7e-17 60.8 0.2 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EJS44261.1 - 0.0074 16.0 4.4 0.21 11.4 0.4 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain DUF2387 PF09526.5 EJS44261.1 - 0.012 15.5 1.8 2.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.8 EJS44261.1 - 0.027 14.1 1.5 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 EJS44261.1 - 0.06 13.1 4.8 1.3 8.9 0.1 2.7 2 1 0 2 2 2 0 Double zinc ribbon UCR_UQCRX_QCR9 PF05365.7 EJS44261.1 - 0.095 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Terminase_GpA PF05876.7 EJS44261.1 - 0.16 10.2 0.8 1.2 7.4 0.6 2.0 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) Baculo_LEF5_C PF11792.3 EJS44261.1 - 0.21 11.0 0.1 0.21 11.0 0.1 2.1 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Zn-ribbon_8 PF09723.5 EJS44261.1 - 1 9.3 10.3 11 6.0 0.2 4.1 4 0 0 4 4 4 0 Zinc ribbon domain IBR PF01485.16 EJS44261.1 - 1.2 9.0 9.2 0.81 9.6 0.1 2.8 2 1 0 2 2 2 0 IBR domain PhnA_Zn_Ribbon PF08274.7 EJS44261.1 - 1.3 8.8 7.9 1 9.2 0.2 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DNA_RNApol_7kD PF03604.8 EJS44261.1 - 3.9 7.0 5.5 4.2 6.9 0.2 2.7 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_5 PF13719.1 EJS44261.1 - 8.7 6.0 12.6 3.6 7.2 0.6 3.8 3 1 1 4 4 4 0 zinc-ribbon domain AA_permease PF00324.16 EJS44262.1 - 1.1e-130 436.2 34.4 1.4e-130 435.8 23.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS44262.1 - 1.8e-33 115.7 34.3 2.4e-33 115.3 23.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 EJS44262.1 - 0.41 9.1 6.4 0.95 7.9 0.0 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) TIM PF00121.13 EJS44263.1 - 2e-89 298.8 0.0 2.3e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase His_Phos_1 PF00300.17 EJS44264.1 - 2.9e-35 121.6 0.0 4.5e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Dfp1_Him1_M PF08630.5 EJS44265.1 - 3.2e-46 156.1 0.0 3.2e-46 156.1 0.0 2.8 3 0 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.7 EJS44265.1 - 3.4e-22 77.8 0.6 7e-22 76.8 0.4 1.6 1 0 0 1 1 1 1 DBF zinc finger HHH_8 PF14716.1 EJS44265.1 - 0.0019 18.3 0.0 0.01 15.9 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain UQ_con PF00179.21 EJS44266.1 - 6.4e-45 152.0 0.1 8.6e-45 151.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EJS44266.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B Recep_L_domain PF01030.19 EJS44267.1 - 2.8e-07 30.4 15.2 0.017 15.0 0.6 4.8 1 1 4 5 5 5 3 Receptor L domain LRR_9 PF14580.1 EJS44267.1 - 0.0012 18.3 0.1 0.0023 17.4 0.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat DUF4339 PF14237.1 EJS44267.1 - 0.016 14.7 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) PFU PF09070.6 EJS44268.1 - 0.00032 20.7 1.5 0.016 15.1 0.0 2.3 2 0 0 2 2 2 2 PFU (PLAA family ubiquitin binding) DUF3242 PF11586.3 EJS44268.1 - 0.011 15.2 0.9 0.018 14.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) DUF1515 PF07439.6 EJS44268.1 - 0.034 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF1183 PF06682.7 EJS44268.1 - 0.13 11.8 0.2 0.17 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) PGAP1 PF07819.8 EJS44269.1 - 9.8e-07 28.5 0.0 2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EJS44269.1 - 4.4e-06 26.1 0.0 2.7e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF915 PF06028.6 EJS44269.1 - 0.00014 21.0 0.2 0.0011 18.1 0.0 2.4 2 1 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 EJS44269.1 - 0.00078 19.2 0.0 0.0016 18.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.10 EJS44269.1 - 0.0044 16.0 0.0 0.0087 15.0 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 EJS44269.1 - 0.007 15.9 0.0 0.0093 15.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 EJS44269.1 - 0.019 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.2 EJS44269.1 - 0.03 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CBF PF03914.12 EJS44270.1 - 4.3e-45 153.0 0.4 4.3e-45 153.0 0.2 3.3 4 0 0 4 4 4 1 CBF/Mak21 family Aminotran_1_2 PF00155.16 EJS44271.1 - 5.2e-74 249.3 0.0 6.3e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EJS44271.1 - 0.011 14.5 0.0 0.02 13.6 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V OKR_DC_1 PF01276.15 EJS44271.1 - 0.014 13.9 0.0 0.026 13.0 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 EJS44271.1 - 0.02 14.0 0.0 0.04 13.0 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase CSS-motif PF12792.2 EJS44271.1 - 0.034 13.4 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 CSS motif domain associated with EAL Cofilin_ADF PF00241.15 EJS44272.1 - 1.6e-06 28.0 0.1 1.9e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RIX1 PF08167.7 EJS44273.1 - 0.05 13.2 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis DUF947 PF06102.7 EJS44273.1 - 0.064 13.0 0.5 0.064 13.0 0.4 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF947) Complex1_LYR_2 PF13233.1 EJS44273.1 - 9.6 6.7 11.0 1.3e+02 3.0 7.6 2.7 1 1 0 1 1 1 0 Complex1_LYR-like Y_phosphatase2 PF03162.8 EJS44274.1 - 6.6e-62 207.7 1.5 8.4e-62 207.3 1.1 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family UCH PF00443.24 EJS44275.1 - 5.1e-68 229.0 0.5 5.1e-68 229.0 0.3 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EJS44275.1 - 1.9e-31 109.6 0.1 1.9e-31 109.6 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EJS44275.1 - 0.00016 21.9 0.0 0.00056 20.2 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Acetyltransf_1 PF00583.19 EJS44277.1 - 7.1e-10 38.7 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EJS44277.1 - 6.2e-09 35.8 0.0 9.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EJS44277.1 - 0.00027 20.7 0.0 0.0021 17.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EJS44277.1 - 0.00092 19.1 0.7 0.0011 18.9 0.1 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EJS44277.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EJS44277.1 - 0.0069 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EJS44277.1 - 0.0099 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PAP2 PF01569.16 EJS44278.1 - 5.1e-09 35.8 7.6 5.1e-09 35.8 5.3 2.9 2 1 0 2 2 2 1 PAP2 superfamily Metallophos PF00149.23 EJS44279.1 - 6.8e-43 146.3 0.1 8.5e-43 146.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EJS44279.1 - 6.3e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Rad51 PF08423.6 EJS44280.1 - 2.6e-07 29.8 0.0 4.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 EJS44280.1 - 4.4e-07 29.2 1.2 8.5e-07 28.3 0.1 2.2 2 1 0 2 2 2 1 KaiC AAA_25 PF13481.1 EJS44280.1 - 1.4e-05 24.5 0.0 9.3e-05 21.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EJS44280.1 - 0.0014 18.7 0.0 0.0088 16.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EJS44280.1 - 0.0037 17.5 1.8 0.016 15.5 0.0 2.7 3 1 0 3 3 3 1 AAA domain DnaB_C PF03796.10 EJS44280.1 - 0.0048 15.8 0.0 0.01 14.7 0.0 1.7 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_11 PF13086.1 EJS44280.1 - 0.051 13.1 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF3883 PF13020.1 EJS44280.1 - 0.08 12.6 0.1 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) IstB_IS21 PF01695.12 EJS44280.1 - 0.1 12.0 0.5 1.3 8.3 0.0 2.8 4 0 0 4 4 4 0 IstB-like ATP binding protein SWIM PF04434.12 EJS44282.1 - 0.00078 18.8 1.3 0.5 9.8 0.0 2.4 2 0 0 2 2 2 2 SWIM zinc finger Tbf5 PF06331.7 EJS44283.1 - 1.2e-28 98.6 0.3 1.4e-28 98.4 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DDE_1 PF03184.14 EJS44284.1 - 2.3e-79 265.5 2.9 4e-79 264.7 2.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EJS44284.1 - 1.1e-14 54.0 0.2 1.1e-14 54.0 0.1 2.5 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DUF846 PF05832.7 EJS44285.1 - 5.3e-47 159.1 9.1 6.7e-47 158.7 6.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) SecE PF00584.15 EJS44287.1 - 6.6e-11 41.6 0.1 7.8e-11 41.3 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Coiled-coil_56 PF09813.4 EJS44287.1 - 0.01 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Nop52 PF05997.7 EJS44288.1 - 7.9e-68 228.1 5.2 9.6e-68 227.8 3.6 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 EJS44288.1 - 0.001 18.8 0.5 0.014 15.1 0.2 2.3 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair DUF3139 PF11337.3 EJS44288.1 - 0.022 15.0 2.8 0.1 12.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) Nucleoplasmin PF03066.10 EJS44288.1 - 0.053 13.0 0.5 0.053 13.0 0.3 2.0 2 0 0 2 2 2 0 Nucleoplasmin DUF4240 PF14024.1 EJS44288.1 - 0.081 12.7 6.0 0.4 10.5 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) Slu7 PF11708.3 EJS44289.1 - 1.1e-42 146.3 20.8 1.1e-42 146.3 14.4 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.18 EJS44289.1 - 0.0027 17.5 3.3 0.0042 16.9 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EJS44289.1 - 0.0053 16.3 1.4 0.013 15.1 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle DUF234 PF03008.9 EJS44289.1 - 0.015 15.4 0.8 0.044 13.8 0.6 1.8 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function SPX PF03105.14 EJS44290.1 - 9.1e-06 25.6 4.0 9.1e-06 25.6 2.8 4.4 3 1 1 4 4 4 2 SPX domain DUF3493 PF11998.3 EJS44290.1 - 0.5 10.2 2.0 1 9.2 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) PQ-loop PF04193.9 EJS44291.1 - 1.2e-21 76.0 9.7 4e-18 64.7 1.3 2.5 2 0 0 2 2 2 2 PQ loop repeat RLL PF10036.4 EJS44291.1 - 0.018 14.4 1.4 0.025 14.0 1.0 1.1 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein ABC2_membrane_5 PF13346.1 EJS44291.1 - 3.9 6.7 23.7 3.1 7.0 10.2 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC_tran PF00005.22 EJS44292.1 - 2.6e-37 128.1 0.0 7.3e-18 65.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EJS44292.1 - 5e-15 54.7 5.4 1.2e-14 53.5 3.7 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EJS44292.1 - 7.1e-14 52.4 10.8 0.0013 18.7 0.0 4.4 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 EJS44292.1 - 1.1e-09 37.9 2.7 0.01 15.1 0.2 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EJS44292.1 - 6e-08 32.1 1.1 0.3 10.1 0.0 4.1 3 1 1 4 4 4 3 AAA ATPase domain Fer4 PF00037.22 EJS44292.1 - 2.9e-07 29.7 3.5 2.9e-07 29.7 2.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain DUF258 PF03193.11 EJS44292.1 - 3.7e-06 26.2 2.3 0.02 14.0 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA PF00004.24 EJS44292.1 - 4.1e-06 27.0 0.1 0.018 15.2 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EJS44292.1 - 9.6e-06 25.0 0.6 0.13 11.7 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EJS44292.1 - 2.5e-05 24.4 0.0 0.013 15.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EJS44292.1 - 0.00014 22.3 0.2 0.36 11.3 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 EJS44292.1 - 0.00014 22.6 0.4 0.74 10.6 0.0 2.8 2 2 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EJS44292.1 - 0.00016 20.6 0.1 0.045 12.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 EJS44292.1 - 0.00017 21.6 0.0 0.046 13.7 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain Fer4_6 PF12837.2 EJS44292.1 - 0.00027 20.6 12.4 0.00038 20.2 2.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_18 PF13238.1 EJS44292.1 - 0.00029 21.1 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Fer4_7 PF12838.2 EJS44292.1 - 0.00047 20.4 7.1 0.00059 20.1 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain MobB PF03205.9 EJS44292.1 - 0.00098 18.8 1.3 0.17 11.6 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_21 PF14697.1 EJS44292.1 - 0.0013 18.5 12.6 0.003 17.3 8.7 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_25 PF13481.1 EJS44292.1 - 0.0025 17.2 0.1 1.5 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EJS44292.1 - 0.0026 16.5 0.0 1 7.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Fer4_2 PF12797.2 EJS44292.1 - 0.0026 17.5 2.4 0.0026 17.5 1.7 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.1 EJS44292.1 - 0.0028 17.5 0.1 0.53 10.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EJS44292.1 - 0.0032 17.6 0.1 0.84 9.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 EJS44292.1 - 0.0034 16.9 0.1 0.084 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EJS44292.1 - 0.0035 17.3 0.0 0.93 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EJS44292.1 - 0.0037 16.9 2.7 0.18 11.4 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Fer4_9 PF13187.1 EJS44292.1 - 0.004 17.3 2.2 0.004 17.3 1.6 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain VirE PF05272.6 EJS44292.1 - 0.0044 16.5 0.0 0.62 9.4 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E AAA_14 PF13173.1 EJS44292.1 - 0.0046 16.8 0.7 3.3 7.6 0.0 3.1 3 1 0 3 3 2 0 AAA domain SRP54 PF00448.17 EJS44292.1 - 0.0054 16.2 3.2 0.18 11.2 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_16 PF13484.1 EJS44292.1 - 0.0055 17.4 0.1 0.0055 17.4 0.1 2.6 2 1 1 3 3 1 1 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 EJS44292.1 - 0.0058 17.1 4.2 0.0058 17.1 2.9 2.5 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_10 PF13237.1 EJS44292.1 - 0.0064 16.2 1.4 0.0064 16.2 1.0 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain UPF0079 PF02367.12 EJS44292.1 - 0.0071 15.9 0.4 0.086 12.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 EJS44292.1 - 0.0093 15.8 0.0 10 6.0 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EJS44292.1 - 0.012 15.3 1.7 0.075 12.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EJS44292.1 - 0.016 15.5 6.9 0.044 14.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EJS44292.1 - 0.037 13.4 2.0 7.2 5.9 0.1 3.5 4 0 0 4 4 3 0 Thymidylate kinase Fer4_4 PF12800.2 EJS44292.1 - 0.042 14.2 2.2 0.042 14.2 1.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain DUF815 PF05673.8 EJS44292.1 - 0.075 11.9 0.1 3 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_17 PF13534.1 EJS44292.1 - 0.1 12.9 0.2 0.1 12.9 0.1 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 EJS44292.1 - 0.11 12.0 0.6 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EJS44292.1 - 0.18 10.7 0.0 0.65 8.8 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EJS44292.1 - 0.18 11.5 2.0 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 NTPase ArgK PF03308.11 EJS44292.1 - 0.22 10.2 0.1 3.1 6.4 0.0 2.1 2 0 0 2 2 2 0 ArgK protein Fer4_8 PF13183.1 EJS44292.1 - 0.28 11.2 8.9 0.11 12.6 0.8 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_19 PF13245.1 EJS44292.1 - 0.32 10.7 1.4 0.74 9.6 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain PduV-EutP PF10662.4 EJS44292.1 - 0.44 10.0 3.4 0.36 10.3 0.1 2.4 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 EJS44292.1 - 1.2 7.5 0.0 1.2 7.5 0.0 2.6 5 0 0 5 5 4 0 AAA domain Fer4_18 PF13746.1 EJS44292.1 - 8.6 6.8 10.4 0.35 11.3 2.5 2.1 1 1 0 2 2 1 0 4Fe-4S dicluster domain JmjC PF02373.17 EJS44293.1 - 2.4e-31 108.3 1.6 3.3e-31 107.8 0.1 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 EJS44293.1 - 6.7e-10 38.3 1.3 6.7e-10 38.3 0.9 1.9 2 0 0 2 2 2 1 jmjN domain zf-H2C2_2 PF13465.1 EJS44293.1 - 3.4e-07 30.2 8.7 3.9e-06 26.8 4.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EJS44293.1 - 1.6e-06 28.0 13.6 0.0017 18.5 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EJS44293.1 - 1.7e-06 28.0 16.5 0.0032 17.7 2.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EJS44293.1 - 0.00022 20.9 9.5 0.0056 16.5 2.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EJS44293.1 - 0.19 11.8 9.7 0.73 10.0 2.9 2.6 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EJS44293.1 - 1.5 8.7 5.4 8.5 6.4 3.7 2.2 1 1 0 1 1 1 0 Zinc ribbon domain zf-met PF12874.2 EJS44293.1 - 5.5 7.3 13.9 2 8.7 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type MutS_V PF00488.16 EJS44294.1 - 2e-74 249.9 0.2 5.2e-74 248.5 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EJS44294.1 - 2.9e-44 151.3 0.5 5.4e-44 150.4 0.4 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EJS44294.1 - 1e-33 115.7 0.0 4.7e-33 113.6 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EJS44294.1 - 6.5e-19 67.8 0.6 1.9e-18 66.3 0.4 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EJS44294.1 - 2.2e-10 40.7 0.0 7.7e-10 38.9 0.0 2.0 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 EJS44294.1 - 0.027 14.0 0.0 0.082 12.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAHP_synth_1 PF00793.15 EJS44295.1 - 5.4e-103 343.3 0.0 6.4e-103 343.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family ECH PF00378.15 EJS44296.1 - 4.2e-30 104.6 0.0 1.1e-29 103.2 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EJS44296.1 - 3.5e-20 72.3 1.0 2.3e-19 69.6 0.2 2.3 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region DHquinase_II PF01220.14 EJS44296.1 - 0.013 14.8 0.3 0.085 12.1 0.2 2.1 2 0 0 2 2 2 0 Dehydroquinase class II AP4E_app_platf PF14807.1 EJS44296.1 - 0.027 14.6 0.8 1.2 9.4 0.2 2.5 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform Sld5 PF05916.6 EJS44297.1 - 4.1e-12 46.3 0.7 5.9e-12 45.8 0.5 1.2 1 0 0 1 1 1 1 GINS complex protein PIF1 PF05970.9 EJS44297.1 - 0.0091 14.9 0.1 0.024 13.5 0.0 1.6 1 1 0 2 2 2 1 PIF1-like helicase Helicase_IV_N PF12462.3 EJS44297.1 - 0.097 12.3 0.5 3.9 7.0 0.1 2.2 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal DUF4062 PF13271.1 EJS44297.1 - 0.14 12.1 0.6 0.77 9.8 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4062) IPK PF03770.11 EJS44298.1 - 3.5e-50 170.3 0.0 3.5e-50 170.3 0.0 2.2 2 1 0 2 2 2 1 Inositol polyphosphate kinase GCV_T PF01571.16 EJS44299.1 - 3.6e-64 216.0 0.0 4.5e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EJS44299.1 - 1.1e-13 51.0 0.0 2.2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain PRK PF00485.13 EJS44300.1 - 1.5e-12 47.4 0.4 2.3e-12 46.9 0.2 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family DUF211 PF02680.9 EJS44300.1 - 0.059 13.1 0.2 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 DEAD PF00270.24 EJS44301.1 - 2.9e-42 144.0 4.2 6e-42 142.9 2.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS44301.1 - 2.4e-27 94.6 0.7 1.3e-26 92.2 0.2 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EJS44301.1 - 9.2e-05 22.1 0.4 0.00022 20.8 0.1 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EJS44301.1 - 9.9e-05 22.4 0.9 0.00037 20.6 0.6 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EJS44301.1 - 0.0012 18.0 4.3 0.0012 18.0 3.0 1.7 2 1 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.1 EJS44301.1 - 0.0014 18.2 0.1 0.0029 17.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.1 EJS44301.1 - 0.0052 15.8 0.1 0.021 13.8 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.9 EJS44301.1 - 0.0063 16.1 0.0 0.013 15.1 0.0 1.6 1 1 0 1 1 1 1 Helicase ResIII PF04851.10 EJS44301.1 - 0.016 15.0 0.3 0.054 13.3 0.2 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EJS44301.1 - 0.036 13.8 0.1 0.1 12.3 0.0 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_C_2 PF13307.1 EJS44301.1 - 0.039 13.9 0.2 0.17 11.8 0.1 2.2 2 2 0 2 2 2 0 Helicase C-terminal domain CobA_CobO_BtuR PF02572.10 EJS44301.1 - 0.046 13.3 0.2 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Atg31 PF09795.4 EJS44302.1 - 1.5e-56 190.4 9.2 1.8e-56 190.2 6.4 1.1 1 0 0 1 1 1 1 Autophagy-related protein 31 tRNA-synt_2b PF00587.20 EJS44303.1 - 1.6e-34 118.9 0.3 4e-34 117.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EJS44303.1 - 1e-23 83.4 8.9 1e-23 83.4 6.2 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 EJS44303.1 - 0.041 12.3 6.0 0.065 11.6 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Myb_DNA-bind_6 PF13921.1 EJS44304.1 - 4.1e-18 65.2 12.7 1.1e-12 47.8 1.3 4.1 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EJS44304.1 - 6.3e-18 64.5 15.4 5.2e-09 36.0 0.6 5.2 4 1 0 4 4 4 3 Myb-like DNA-binding domain Zip PF02535.17 EJS44304.1 - 1.6 7.7 4.4 2.5 7.0 3.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Vps54 PF07928.7 EJS44305.1 - 0.00041 20.4 0.2 0.0013 18.8 0.1 1.9 1 0 0 1 1 1 1 Vps54-like protein SHOCT PF09851.4 EJS44305.1 - 2.2 7.8 7.4 0.18 11.3 0.3 2.8 3 0 0 3 3 3 0 Short C-terminal domain DUF1752 PF08550.5 EJS44306.1 - 6.7e-11 41.5 1.6 1.3e-10 40.6 1.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) WD40 PF00400.27 EJS44307.1 - 7.2e-19 66.9 9.2 3.1e-06 26.8 0.2 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat D5_N PF08706.6 EJS44307.1 - 0.048 13.7 0.1 0.25 11.4 0.0 2.1 1 1 1 2 2 2 0 D5 N terminal like CHCH PF06747.8 EJS44308.1 - 1.4e-08 34.3 10.7 6.9e-06 25.8 0.4 3.0 2 1 0 2 2 2 2 CHCH domain UPF0203 PF05254.7 EJS44308.1 - 7.7e-06 25.6 10.2 0.001 18.8 1.3 3.2 1 1 2 3 3 3 3 Uncharacterised protein family (UPF0203) GCK PF07802.6 EJS44308.1 - 5.6e-05 23.1 6.5 0.04 14.0 0.2 2.2 1 1 1 2 2 2 2 GCK domain UCR_hinge PF02320.11 EJS44308.1 - 0.0047 16.8 1.3 0.0047 16.8 0.9 2.3 1 1 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.5 EJS44308.1 - 0.005 16.5 9.3 0.21 11.4 1.9 2.8 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 EJS44308.1 - 0.0065 15.8 8.1 0.057 12.8 0.2 2.6 1 1 2 3 3 3 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Phage_1_1 PF08200.6 EJS44308.1 - 0.01 16.0 0.1 0.054 13.7 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein COX6B PF02297.12 EJS44308.1 - 0.01 15.8 7.5 0.019 14.9 0.3 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EJS44308.1 - 0.061 13.3 10.7 0.14 12.2 1.5 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EJS44308.1 - 0.53 10.3 7.9 3.8 7.5 0.8 2.9 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) FMN_red PF03358.10 EJS44309.1 - 4e-10 39.4 0.0 5.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EJS44309.1 - 4.8e-08 33.1 0.1 1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.12 EJS44309.1 - 9.7e-05 21.9 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Fungal_trans_2 PF11951.3 EJS44310.1 - 9e-21 73.8 2.8 1.9e-20 72.7 1.9 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS44310.1 - 8.2e-07 28.8 13.0 1.7e-06 27.8 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 EJS44311.1 - 2.1e-40 137.9 0.0 3.7e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EJS44311.1 - 3.3e-06 27.2 0.1 0.0018 18.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EJS44311.1 - 1.2e-05 25.3 0.0 3.5e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EJS44311.1 - 2e-05 23.6 0.0 3.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EJS44311.1 - 0.00012 21.8 0.1 0.00057 19.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EJS44311.1 - 0.00038 20.4 0.0 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EJS44311.1 - 0.0013 17.8 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EJS44311.1 - 0.0016 18.4 0.6 0.004 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EJS44311.1 - 0.004 17.0 0.0 0.0095 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EJS44311.1 - 0.0055 17.5 0.6 0.013 16.3 0.1 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EJS44311.1 - 0.007 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EJS44311.1 - 0.007 16.6 0.2 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EJS44311.1 - 0.0084 15.8 0.6 0.018 14.8 0.4 1.4 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EJS44311.1 - 0.01 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 EJS44311.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EJS44311.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EJS44311.1 - 0.013 14.3 0.0 0.048 12.5 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.8 EJS44311.1 - 0.022 13.4 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus NTPase_1 PF03266.10 EJS44311.1 - 0.031 14.0 0.1 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 EJS44311.1 - 0.034 14.3 0.0 0.086 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EJS44311.1 - 0.035 13.4 3.1 0.22 10.9 0.3 2.5 2 1 1 3 3 3 0 AAA domain PhoH PF02562.11 EJS44311.1 - 0.037 13.2 0.2 0.19 10.9 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 EJS44311.1 - 0.049 12.7 0.1 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EJS44311.1 - 0.053 13.0 0.2 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EJS44311.1 - 0.059 12.4 0.0 0.39 9.7 0.0 2.1 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 EJS44311.1 - 0.074 12.7 0.1 0.32 10.6 0.1 2.0 2 0 0 2 2 2 0 NACHT domain PP2C PF00481.16 EJS44312.1 - 4.1e-78 262.3 0.3 8.7e-78 261.2 0.2 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EJS44312.1 - 0.00074 19.2 0.1 0.0033 17.1 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Med2 PF11214.3 EJS44313.1 - 1e-32 112.2 19.1 2.2e-31 107.9 13.3 2.5 1 1 0 1 1 1 1 Mediator complex subunit 2 ATP-synt_DE_N PF02823.11 EJS44314.1 - 1.8e-19 69.2 0.0 2.5e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Rad21_Rec8_N PF04825.8 EJS44315.1 - 1.3e-24 86.3 0.8 2.8e-24 85.1 0.2 1.8 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EJS44315.1 - 6.6e-14 50.8 0.0 1.2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EJS44315.1 - 0.00075 19.1 0.3 0.00075 19.1 0.2 2.4 2 1 1 3 3 3 1 ScpA/B protein DUF155 PF02582.9 EJS44316.1 - 3e-61 206.3 2.4 5.4e-61 205.5 1.7 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 EJS44316.1 - 0.03 14.5 0.0 0.089 13.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Trehalase PF01204.13 EJS44317.1 - 3.7e-190 632.9 0.1 4.4e-190 632.6 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EJS44317.1 - 1.2e-16 59.6 0.9 2.2e-16 58.8 0.6 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ran_BP1 PF00638.13 EJS44318.1 - 1.2e-56 190.0 2.4 1.7e-56 189.5 1.7 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EJS44318.1 - 4.7e-05 23.0 1.4 0.0005 19.7 1.0 2.1 1 1 0 1 1 1 1 WH1 domain BRAP2 PF07576.7 EJS44318.1 - 0.082 12.4 0.2 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 BRCA1-associated protein 2 PRCH PF03967.8 EJS44318.1 - 0.19 11.3 1.1 0.37 10.3 0.8 1.5 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region RCR PF12273.3 EJS44319.1 - 1.6e-41 141.9 0.5 2.8e-41 141.1 0.1 1.6 1 1 1 2 2 2 1 Chitin synthesis regulation, resistance to Congo red ATG27 PF09451.5 EJS44319.1 - 0.013 14.6 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF3753 PF12575.3 EJS44319.1 - 0.053 13.3 0.2 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF2975 PF11188.3 EJS44319.1 - 0.053 13.2 0.6 0.079 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Tcp11 PF05794.8 EJS44320.1 - 7.7e-124 413.7 3.0 1.4e-123 412.9 2.1 1.4 1 0 0 1 1 1 1 T-complex protein 11 GalKase_gal_bdg PF10509.4 EJS44321.1 - 4.1e-21 73.9 0.0 9.2e-21 72.8 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EJS44321.1 - 6.2e-12 45.4 0.1 2e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EJS44321.1 - 6.3e-09 35.9 0.0 1.9e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Git3 PF11710.3 EJS44322.1 - 3.7e-86 287.8 7.7 5.8e-86 287.2 5.3 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EJS44322.1 - 2.2e-32 110.6 2.5 2.2e-32 110.6 1.7 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DEAD PF00270.24 EJS44323.1 - 1.1e-46 158.3 0.0 9.9e-46 155.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EJS44323.1 - 7.2e-22 76.9 6.7 7.2e-22 76.9 4.7 3.5 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EJS44323.1 - 2.9e-21 75.0 0.0 1.3e-20 73.0 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3449 PF11931.3 EJS44324.1 - 2.4e-66 223.0 0.1 2.4e-66 223.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 EJS44324.1 - 1.6e-09 37.6 0.2 0.00026 21.0 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EJS44324.1 - 4.1e-08 33.1 0.5 0.00057 19.9 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EJS44324.1 - 0.018 15.1 1.4 0.42 10.7 0.1 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EJS44324.1 - 0.14 12.5 9.8 1.1 9.7 1.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EJS44324.1 - 1 9.7 3.8 7 7.1 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.20 EJS44325.1 - 3e-50 170.8 0.0 6.6e-50 169.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44325.1 - 3.9e-22 78.5 0.0 1e-21 77.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EJS44325.1 - 0.00022 21.0 0.0 0.084 12.5 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EJS44325.1 - 0.018 14.3 0.1 0.048 12.9 0.1 1.7 1 0 0 1 1 1 0 RIO1 family NAD_Gly3P_dh_N PF01210.18 EJS44327.1 - 1.1e-54 184.4 0.1 1.7e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EJS44327.1 - 7.6e-47 158.7 0.0 1.2e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EJS44327.1 - 0.032 14.6 0.0 15 6.1 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent His_Phos_1 PF00300.17 EJS44328.1 - 2.9e-43 147.6 0.1 8.6e-43 146.1 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-C2H2_4 PF13894.1 EJS44329.1 - 0.00053 20.1 1.4 0.045 14.0 0.1 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EJS44329.1 - 0.011 16.0 0.2 0.011 16.0 0.1 3.9 4 1 0 4 4 4 0 Zinc finger, C2H2 type PBP1_TM PF14812.1 EJS44329.1 - 4.8 7.5 17.0 11 6.3 4.0 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2_6 PF13912.1 EJS44329.1 - 7.9 6.5 7.0 2.3 8.2 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Oxysterol_BP PF01237.13 EJS44330.1 - 1.2e-132 441.7 0.6 1.9e-132 441.0 0.4 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.1 EJS44330.1 - 9.7e-13 47.9 0.4 3.3e-06 27.1 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EJS44330.1 - 8.5e-12 45.2 0.1 4e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EJS44330.1 - 5.2e-10 38.6 0.0 1.5e-05 24.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EJS44330.1 - 1.4e-09 38.1 0.1 0.00026 21.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 EJS44330.1 - 1.6e-09 37.8 0.1 5.6e-09 36.1 0.0 2.0 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.1 EJS44330.1 - 6.9e-09 35.0 0.3 0.00043 20.2 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.1 EJS44330.1 - 3.7e-07 30.1 0.1 1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EJS44330.1 - 2.6e-05 24.4 0.3 2.6e-05 24.4 0.2 2.9 2 2 0 2 2 2 1 Pleckstrin homology domain EMP24_GP25L PF01105.19 EJS44331.1 - 5e-35 120.8 0.2 6.7e-35 120.4 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 EJS44332.1 - 4.8e-41 140.6 0.0 4.5e-23 81.7 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44332.1 - 1.5e-13 50.4 0.0 9.8e-09 34.6 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EJS44332.1 - 0.00082 18.4 0.0 0.97 8.3 0.0 2.9 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EJS44332.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Steroid_dh PF02544.11 EJS44333.1 - 4.6e-45 153.0 12.4 7.8e-45 152.3 8.6 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Fibrillarin PF01269.12 EJS44334.1 - 5.2e-110 365.7 0.0 6.4e-110 365.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EJS44334.1 - 2.7e-05 23.7 0.1 5.2e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EJS44334.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-C3HC4_2 PF13923.1 EJS44335.1 - 0.0071 16.3 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EJS44335.1 - 0.011 15.4 0.1 0.011 15.4 0.1 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EJS44335.1 - 0.028 14.0 0.1 0.071 12.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1980 PF09323.5 EJS44335.1 - 0.034 13.8 0.2 0.063 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Fer2_3 PF13085.1 EJS44335.1 - 0.06 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain FUSC-like PF12805.2 EJS44335.1 - 0.23 10.3 5.2 0.081 11.8 0.4 2.2 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS DUF3164 PF11363.3 EJS44335.1 - 0.33 10.3 3.1 0.34 10.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3164) Glutaredoxin PF00462.19 EJS44336.1 - 1e-10 41.3 0.0 2.4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin ExbD PF02472.11 EJS44336.1 - 0.25 11.3 1.8 0.46 10.4 1.3 1.7 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR zf-Apc11 PF12861.2 EJS44337.1 - 4.7e-47 157.7 6.5 6.2e-47 157.3 4.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EJS44337.1 - 3e-30 104.1 8.2 4.4e-30 103.6 5.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EJS44337.1 - 1.7e-06 27.7 17.4 7.5e-06 25.6 12.1 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EJS44337.1 - 0.00089 18.9 13.0 0.011 15.4 9.4 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EJS44337.1 - 0.03 14.3 14.4 0.22 11.5 10.0 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CpXC PF14353.1 EJS44337.1 - 0.07 13.0 3.1 0.15 11.9 2.1 1.6 1 1 0 1 1 1 0 CpXC protein zf-C3HC4_3 PF13920.1 EJS44337.1 - 0.086 12.5 13.3 4 7.1 9.3 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EJS44337.1 - 0.13 11.9 16.0 1.1 9.0 11.1 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EJS44337.1 - 0.28 11.0 10.2 31 4.5 7.0 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 EJS44337.1 - 0.38 10.3 15.2 0.11 12.1 1.9 3.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EJS44337.1 - 2.5 8.1 8.1 0.84 9.6 3.3 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain RINGv PF12906.2 EJS44337.1 - 4.4 7.4 8.6 18 5.4 6.0 2.1 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EJS44337.1 - 5 7.1 16.8 1e+02 2.9 11.7 3.1 1 1 0 1 1 1 0 FANCL C-terminal domain IATP PF04568.7 EJS44339.1 - 3.6e-20 71.8 0.4 3.9e-20 71.7 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP AAA_23 PF13476.1 EJS44339.1 - 0.03 14.6 0.3 0.03 14.6 0.2 1.1 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 EJS44339.1 - 0.052 13.9 0.9 0.063 13.7 0.6 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CENP-H PF05837.7 EJS44339.1 - 0.065 13.4 1.9 0.079 13.1 1.3 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DIX PF00778.12 EJS44339.1 - 0.078 12.7 0.2 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 DIX domain Bromodomain PF00439.20 EJS44339.1 - 0.085 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Bromodomain DUF2730 PF10805.3 EJS44339.1 - 0.094 12.4 1.0 0.13 11.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) HR1 PF02185.11 EJS44339.1 - 0.15 11.8 4.7 0.2 11.3 3.3 1.3 1 0 0 1 1 1 0 Hr1 repeat FbpA PF05833.6 EJS44339.1 - 0.26 9.7 6.0 0.3 9.5 4.1 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DivIC PF04977.10 EJS44339.1 - 0.89 9.0 4.8 1.3 8.5 3.3 1.3 1 0 0 1 1 1 0 Septum formation initiator Na_Ca_ex PF01699.19 EJS44341.1 - 4.6e-53 178.5 29.8 1.6e-27 95.8 4.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SHP PF03579.8 EJS44341.1 - 0.051 12.9 1.8 0.12 11.7 0.1 2.6 2 0 0 2 2 2 0 Small hydrophobic protein AAA PF00004.24 EJS44342.1 - 4.4e-98 324.6 0.0 5e-48 162.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EJS44342.1 - 1e-19 70.2 0.4 3.1e-19 68.6 0.3 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EJS44342.1 - 9.9e-14 51.6 0.0 2.8e-07 30.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EJS44342.1 - 1.6e-13 50.2 0.0 1.4e-05 24.2 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EJS44342.1 - 1.3e-12 47.6 1.6 2e-06 27.5 0.0 3.9 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EJS44342.1 - 5.3e-12 46.1 0.0 0.0004 20.4 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EJS44342.1 - 1.6e-11 44.2 0.0 6.7e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EJS44342.1 - 2.7e-11 44.3 0.1 0.0011 19.7 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EJS44342.1 - 2.9e-10 40.3 3.7 0.0012 18.9 0.1 4.3 3 2 0 3 3 2 2 AAA domain TIP49 PF06068.8 EJS44342.1 - 3.1e-09 36.0 0.0 0.0012 17.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus CDC48_2 PF02933.12 EJS44342.1 - 1.7e-08 33.9 0.0 4.4e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EJS44342.1 - 1.9e-08 34.2 0.0 0.004 17.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 EJS44342.1 - 8.7e-08 31.7 0.1 0.0074 15.7 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EJS44342.1 - 1.8e-07 30.8 0.9 0.025 14.3 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EJS44342.1 - 2.4e-07 30.8 0.0 0.011 15.9 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 EJS44342.1 - 4.2e-07 29.3 0.5 0.031 13.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EJS44342.1 - 5.2e-07 29.2 6.9 0.028 13.8 0.1 4.2 2 2 2 4 4 4 2 AAA domain Zeta_toxin PF06414.7 EJS44342.1 - 5.3e-07 28.9 0.0 0.011 14.8 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin AAA_24 PF13479.1 EJS44342.1 - 1.8e-06 27.6 0.1 0.11 12.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain KaiC PF06745.8 EJS44342.1 - 2.6e-06 26.7 2.6 0.34 10.0 0.0 3.8 2 2 1 3 3 3 2 KaiC ResIII PF04851.10 EJS44342.1 - 9e-06 25.6 0.0 0.0098 15.7 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EJS44342.1 - 1.1e-05 25.7 0.0 0.047 13.9 0.0 3.9 3 1 0 3 3 2 1 ABC transporter AAA_18 PF13238.1 EJS44342.1 - 1.2e-05 25.6 0.0 0.19 12.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EJS44342.1 - 1.2e-05 24.8 0.1 0.13 11.7 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 EJS44342.1 - 1.3e-05 25.2 0.0 0.24 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EJS44342.1 - 2.4e-05 23.6 0.5 0.12 11.6 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.12 EJS44342.1 - 2.8e-05 23.1 0.1 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EJS44342.1 - 3e-05 23.7 0.0 0.21 11.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EJS44342.1 - 4.4e-05 23.5 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 EJS44342.1 - 7.6e-05 21.7 0.0 0.11 11.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.6 EJS44342.1 - 0.00012 21.7 0.0 0.66 9.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EJS44342.1 - 0.00013 21.7 0.1 0.0015 18.3 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.13 EJS44342.1 - 0.00018 21.2 0.0 0.42 10.2 0.0 3.2 4 0 0 4 4 2 1 Bacterial dnaA protein NACHT PF05729.7 EJS44342.1 - 0.00021 20.9 0.1 1.7 8.3 0.0 3.5 3 0 0 3 3 3 1 NACHT domain Arch_ATPase PF01637.13 EJS44342.1 - 0.00042 20.0 2.1 0.64 9.6 0.1 3.9 3 2 2 5 5 3 1 Archaeal ATPase AAA_30 PF13604.1 EJS44342.1 - 0.00046 19.8 0.0 1.6 8.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 EJS44342.1 - 0.00051 19.1 0.0 0.69 8.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EJS44342.1 - 0.0052 15.6 0.1 1.8 7.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 EJS44342.1 - 0.0076 15.9 1.2 3.3 7.3 0.0 4.2 4 0 0 4 4 4 0 NTPase Zot PF05707.7 EJS44342.1 - 0.0092 15.4 0.2 5.5 6.4 0.0 4.0 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) IPT PF01745.11 EJS44342.1 - 0.014 14.5 0.1 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 EJS44342.1 - 0.019 13.9 0.2 1.6 7.6 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain SKI PF01202.17 EJS44342.1 - 0.054 13.3 0.0 4.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 EJS44342.1 - 0.055 13.0 0.1 6.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 UFD1 PF03152.9 EJS44342.1 - 0.07 12.2 0.0 0.47 9.5 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 DEAD PF00270.24 EJS44342.1 - 0.18 11.2 0.3 25 4.3 0.0 3.3 3 1 1 4 4 4 0 DEAD/DEAH box helicase Aldo_ket_red PF00248.16 EJS44343.1 - 1.5e-42 145.4 0.0 1.8e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OAS1_C PF10421.4 EJS44343.1 - 0.052 13.0 0.1 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Pmp3 PF01679.12 EJS44344.1 - 1.8e-20 72.3 5.7 2.4e-20 71.9 3.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Frataxin_Cyay PF01491.11 EJS44346.1 - 7.7e-33 112.5 0.0 1.1e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Snf7 PF03357.16 EJS44346.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Snf7 Mito_carr PF00153.22 EJS44347.1 - 5.5e-54 179.8 1.7 8.4e-20 70.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1762 PF08574.5 EJS44348.1 - 2.3e-21 75.9 10.4 2.3e-21 75.9 7.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) PX PF00787.19 EJS44349.1 - 9.4e-24 83.3 3.8 2e-23 82.3 0.0 2.9 3 0 0 3 3 3 1 PX domain FTCD_C PF04961.7 EJS44349.1 - 0.051 12.9 3.4 0.1 11.9 0.4 2.3 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Baculo_PEP_C PF04513.7 EJS44349.1 - 1.2 8.9 6.9 3.6 7.3 0.1 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EJS44349.1 - 6 7.1 12.1 39 4.5 0.3 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein SpoU_methylase PF00588.14 EJS44350.1 - 7.3e-26 90.7 0.0 1.6e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family RNase_PH PF01138.16 EJS44351.1 - 3.9e-13 49.8 0.2 5.8e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EJS44351.1 - 0.0025 17.7 0.0 0.0067 16.3 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Spc7 PF08317.6 EJS44352.1 - 0.0082 14.8 3.5 0.0099 14.5 2.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Use1 PF09753.4 EJS44352.1 - 0.011 15.1 0.2 0.016 14.6 0.2 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 Med9 PF07544.8 EJS44352.1 - 0.017 14.8 0.8 0.072 12.8 0.0 2.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.7 EJS44352.1 - 0.059 13.1 0.4 0.08 12.7 0.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EJS44352.1 - 0.079 12.5 0.8 0.089 12.3 0.5 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EJS44352.1 - 0.31 10.5 3.1 0.2 11.1 0.6 1.8 2 0 0 2 2 2 0 Septum formation initiator APG6 PF04111.7 EJS44352.1 - 0.49 9.3 3.3 0.6 9.1 2.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc24 PF08286.6 EJS44352.1 - 0.82 9.3 7.4 9.3 5.9 5.1 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Homeobox PF00046.24 EJS44353.1 - 2.8e-17 62.0 0.5 2.8e-17 62.0 0.3 1.7 2 0 0 2 2 2 1 Homeobox domain IncA PF04156.9 EJS44353.1 - 2.9 7.4 18.2 4.9 6.6 12.6 1.3 1 0 0 1 1 1 0 IncA protein Med15 PF09606.5 EJS44353.1 - 4.3 5.4 38.8 6.4 4.8 26.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal UDPGP PF01704.13 EJS44354.1 - 9e-46 156.2 0.0 1.2e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EJS44354.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain DNA_pol_B PF00136.16 EJS44355.1 - 7.2e-135 450.3 0.5 1.1e-134 449.7 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EJS44355.1 - 3e-94 315.5 1.1 5.4e-94 314.7 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EJS44355.1 - 8.2e-23 80.2 4.7 1.7e-22 79.1 3.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 EJS44355.1 - 0.00087 18.8 0.1 0.0026 17.3 0.0 1.8 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.8 EJS44355.1 - 0.00091 18.0 3.3 0.0036 16.0 0.4 2.4 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 EJS44355.1 - 0.013 15.3 0.5 0.013 15.3 0.4 2.8 3 1 0 3 3 3 0 RNase_H superfamily Pkinase PF00069.20 EJS44356.1 - 3e-73 246.1 0.0 3.8e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44356.1 - 2.3e-36 125.2 0.0 3.3e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EJS44356.1 - 1.6e-18 66.6 0.5 4e-18 65.3 0.4 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EJS44356.1 - 0.00044 19.3 6.0 0.3 10.0 0.3 3.6 2 2 2 4 4 4 3 Kinase-like YrbL-PhoP_reg PF10707.4 EJS44356.1 - 0.023 14.0 0.9 0.049 12.9 0.6 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EJS44356.1 - 0.027 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ArsA_ATPase PF02374.10 EJS44357.1 - 9e-120 399.3 0.0 1e-119 399.1 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EJS44357.1 - 1.1e-12 47.7 0.2 1.8e-12 47.0 0.1 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EJS44357.1 - 0.00054 19.9 0.0 0.0038 17.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EJS44357.1 - 0.0013 17.9 0.0 0.0029 16.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EJS44357.1 - 0.012 15.0 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EJS44357.1 - 0.028 13.8 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EJS44357.1 - 0.062 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EJS44357.1 - 0.066 12.8 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain T2SE PF00437.15 EJS44357.1 - 0.16 10.8 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TMF_DNA_bd PF12329.3 EJS44358.1 - 0.012 15.3 20.3 0.012 15.3 14.1 3.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 EJS44358.1 - 0.066 12.9 24.4 0.74 9.5 4.2 3.5 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EJS44358.1 - 0.087 11.9 5.5 0.038 13.1 2.3 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF2408 PF10303.4 EJS44358.1 - 0.13 12.4 16.7 0.017 15.2 5.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) ERM PF00769.14 EJS44358.1 - 2.3 7.7 40.1 0.28 10.6 14.9 2.4 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Allexi_40kDa PF05549.6 EJS44358.1 - 2.8 7.1 11.9 0.2 10.9 4.5 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF745 PF05335.8 EJS44358.1 - 4.8 6.6 16.0 0.39 10.2 2.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Atg14 PF10186.4 EJS44358.1 - 6.1 5.6 21.4 0.16 10.8 8.6 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GLE1 PF07817.8 EJS44358.1 - 6.3 5.6 11.1 0.17 10.7 2.9 1.9 2 0 0 2 2 2 0 GLE1-like protein TMPIT PF07851.8 EJS44358.1 - 8.1 5.4 10.8 0.5 9.3 3.0 2.1 2 0 0 2 2 2 0 TMPIT-like protein zf-met PF12874.2 EJS44359.1 - 2.5e-05 24.3 0.9 2.5e-05 24.3 0.6 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EJS44359.1 - 8e-05 22.6 1.1 0.00017 21.6 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EJS44359.1 - 0.026 14.4 0.8 0.026 14.4 0.5 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger Rtf2 PF04641.7 EJS44359.1 - 0.04 13.1 0.8 0.3 10.2 0.1 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C2H2_4 PF13894.1 EJS44359.1 - 0.1 12.9 0.7 0.34 11.3 0.5 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DBF PF07535.7 EJS44359.1 - 9.4 6.0 7.4 0.4 10.3 0.4 2.2 3 0 0 3 3 3 0 DBF zinc finger PCI PF01399.22 EJS44360.1 - 3.3e-18 65.9 1.9 6.2e-18 65.0 0.0 2.4 3 0 0 3 3 3 1 PCI domain TPR_16 PF13432.1 EJS44360.1 - 3.2e-05 24.4 0.3 0.042 14.5 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 EJS44360.1 - 9.4e-05 21.6 2.6 9.4e-05 21.6 1.8 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EJS44360.1 - 0.0066 16.0 3.2 0.8 9.4 0.0 3.9 3 0 0 3 3 3 1 TPR repeat TPR_21 PF09976.4 EJS44360.1 - 0.0097 15.8 1.1 4.9 7.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat DDRGK PF09756.4 EJS44360.1 - 0.025 14.0 0.1 0.025 14.0 0.1 2.4 2 1 0 2 2 2 0 DDRGK domain TPR_19 PF14559.1 EJS44360.1 - 0.064 13.5 4.9 9.7 6.6 0.0 4.1 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EJS44360.1 - 0.12 12.1 3.8 13 5.9 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EJS44360.1 - 0.13 12.2 9.8 0.51 10.3 0.5 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 EJS44360.1 - 0.35 10.7 4.3 20 5.0 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EJS44360.1 - 0.94 9.5 11.7 17 5.6 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Rapamycin_bind PF08771.6 EJS44360.1 - 5.9 7.0 8.6 8.6 6.5 0.1 4.1 4 2 2 6 6 6 0 Rapamycin binding domain PMT PF02366.13 EJS44361.1 - 8.7e-88 293.8 20.7 8.7e-88 293.8 14.3 2.9 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EJS44361.1 - 3.6e-56 189.7 0.1 5.8e-56 189.0 0.1 1.3 1 0 0 1 1 1 1 MIR domain SRP14 PF02290.10 EJS44362.1 - 2.1e-25 88.4 1.2 2.2e-25 88.3 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle 14kD protein UBX PF00789.15 EJS44363.1 - 1.6e-21 76.1 0.0 3.5e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain LAM_C PF12544.3 EJS44363.1 - 0.16 11.9 1.8 0.38 10.8 1.3 1.6 1 0 0 1 1 1 0 Lysine-2,3-aminomutase DUF2418 PF10332.4 EJS44364.1 - 2.3e-24 85.5 1.1 2.3e-24 85.5 0.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Nup35_RRM PF05172.8 EJS44365.1 - 1.6e-40 136.9 0.0 4.4e-40 135.5 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EJS44365.1 - 1.8e-07 30.8 0.1 9e-05 22.1 0.1 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif LUC7 PF03194.10 EJS44366.1 - 1e-79 267.6 6.7 1.1e-79 267.5 4.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF1104 PF06518.6 EJS44366.1 - 0.02 15.0 3.0 0.25 11.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) Ribosomal_L17 PF01196.14 EJS44366.1 - 0.066 13.7 0.3 0.17 12.4 0.2 1.7 1 0 0 1 1 1 0 Ribosomal protein L17 DLH PF01738.13 EJS44367.1 - 2.5e-22 79.2 0.0 2.8e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EJS44367.1 - 3.4e-05 23.6 0.0 4.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EJS44367.1 - 0.0003 20.0 0.0 0.0066 15.6 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EJS44367.1 - 0.044 12.6 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2305 PF10230.4 EJS44367.1 - 0.088 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) 6PF2K PF01591.13 EJS44367.1 - 0.088 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Chlorophyllase PF07224.6 EJS44367.1 - 0.13 11.0 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase 4F5 PF04419.9 EJS44368.1 - 2e-08 34.8 13.2 2e-08 34.8 9.1 2.2 2 1 0 2 2 2 1 4F5 protein family DUF1423 PF07227.6 EJS44368.1 - 2.2 6.8 9.2 2.6 6.6 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DDRGK PF09756.4 EJS44368.1 - 6.4 6.1 13.9 7.2 5.9 9.6 1.0 1 0 0 1 1 1 0 DDRGK domain Pyr_redox_2 PF07992.9 EJS44369.1 - 1.2e-23 84.0 0.0 2e-14 53.9 0.0 3.5 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EJS44369.1 - 8.7e-12 45.2 0.0 5.5e-10 39.5 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EJS44369.1 - 4.5e-06 26.8 0.0 0.0026 17.8 0.0 3.2 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EJS44369.1 - 0.043 13.5 0.1 12 5.6 0.0 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding DEAD PF00270.24 EJS44370.1 - 4e-35 120.8 0.2 1.2e-34 119.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS44370.1 - 9.3e-23 79.8 0.0 1e-21 76.5 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EJS44370.1 - 1.3e-05 25.1 0.1 3.8e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.14 EJS44371.1 - 3.2e-22 78.7 6.8 3.8e-22 78.4 4.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ldh_1_C PF02866.13 EJS44372.1 - 5.5e-49 166.2 0.0 7.4e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EJS44372.1 - 3e-44 150.2 0.1 4.8e-44 149.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EJS44372.1 - 0.0005 20.3 0.1 0.0014 18.9 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EJS44372.1 - 0.032 12.9 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Vps39_1 PF10366.4 EJS44373.1 - 3.5e-33 113.8 1.0 3.5e-33 113.8 0.7 3.2 4 1 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EJS44373.1 - 8.5e-12 45.2 0.0 2.8e-11 43.5 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Rxt3 PF08642.5 EJS44374.1 - 2.6e-35 121.1 0.0 5.5e-35 120.0 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 BRE1 PF08647.6 EJS44375.1 - 9.2e-31 105.6 8.6 9.2e-31 105.6 5.9 5.4 5 0 0 5 5 5 2 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EJS44375.1 - 1.6e-06 27.9 13.8 3.4e-06 26.9 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EJS44375.1 - 4e-06 26.3 12.3 7.7e-06 25.4 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EJS44375.1 - 1.4e-05 24.7 13.8 2.9e-05 23.6 9.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EJS44375.1 - 0.00011 21.7 14.4 0.00011 21.7 10.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EJS44375.1 - 0.0017 18.1 11.1 0.0037 17.0 7.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C2H2 PF00096.21 EJS44375.1 - 0.004 17.4 2.8 0.0045 17.2 0.1 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-RING_UBOX PF13445.1 EJS44375.1 - 0.024 14.3 8.2 0.14 11.8 5.7 2.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EJS44375.1 - 0.044 13.3 5.6 0.1 12.1 3.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EJS44375.1 - 0.082 12.7 4.5 0.18 11.5 3.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EJS44375.1 - 2.7 7.6 11.7 6.2 6.4 8.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Reo_sigmaC PF04582.7 EJS44375.1 - 3.2 6.8 26.8 0.55 9.3 1.2 4.8 2 1 3 5 5 5 0 Reovirus sigma C capsid protein zf-C3HC4_4 PF15227.1 EJS44375.1 - 5.4 6.9 10.7 17 5.4 7.4 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Bcr-Abl_Oligo PF09036.5 EJS44375.1 - 5.7 6.9 10.4 0.45 10.4 0.2 3.7 4 1 1 5 5 5 0 Bcr-Abl oncoprotein oligomerisation domain FYVE PF01363.16 EJS44375.1 - 6.6 6.7 14.6 1.2e+02 2.7 10.2 2.5 1 1 0 1 1 1 0 FYVE zinc finger DUF1765 PF08578.5 EJS44376.1 - 1.2e-23 83.5 6.2 1.2e-23 83.5 4.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Bap31 PF05529.7 EJS44377.1 - 3.6e-55 186.4 0.5 4e-55 186.2 0.4 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like BofA PF07441.6 EJS44377.1 - 0.043 13.7 0.2 0.043 13.7 0.1 2.2 3 0 0 3 3 3 0 SigmaK-factor processing regulatory protein BofA FSH1 PF03959.8 EJS44378.1 - 0.039 13.4 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Iso_dh PF00180.15 EJS44379.1 - 1.9e-69 234.2 0.0 2.3e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pex19 PF04614.7 EJS44380.1 - 5.1e-63 212.9 11.3 5.1e-63 212.9 7.9 1.4 1 1 1 2 2 2 1 Pex19 protein family CobN-Mg_chel PF02514.11 EJS44380.1 - 0.05 10.9 1.8 0.042 11.2 0.2 1.5 2 0 0 2 2 2 0 CobN/Magnesium Chelatase ESCRT-II PF05871.7 EJS44380.1 - 0.12 12.3 0.4 0.26 11.1 0.3 1.6 1 0 0 1 1 1 0 ESCRT-II complex subunit XPC-binding PF09280.6 EJS44380.1 - 0.17 11.3 1.9 0.35 10.3 0.1 2.4 2 0 0 2 2 2 0 XPC-binding domain DUF4061 PF13270.1 EJS44380.1 - 2.6 8.1 7.2 7.6 6.7 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4061) Ribosomal_S14 PF00253.16 EJS44381.1 - 3e-18 64.9 4.2 3.3e-18 64.7 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EJS44381.1 - 0.042 13.6 0.4 0.05 13.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Prim_Zn_Ribbon PF08273.7 EJS44381.1 - 0.08 13.0 2.2 1.6 8.8 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2296 PF10058.4 EJS44381.1 - 0.16 11.7 1.8 8.1 6.2 1.7 2.1 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) RNA_POL_M_15KD PF02150.11 EJS44381.1 - 0.22 11.2 1.5 6.3 6.5 0.1 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DUF663 PF04950.7 EJS44382.1 - 2e-109 365.1 0.0 4.3e-109 364.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EJS44382.1 - 3.4e-25 87.3 0.0 7.7e-25 86.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Abhydrolase_5 PF12695.2 EJS44383.1 - 1.1e-12 47.9 0.0 1.9e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EJS44383.1 - 1.5e-11 44.5 0.0 6.4e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EJS44383.1 - 2.7e-06 27.1 0.0 5.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EJS44383.1 - 0.02 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EJS44383.1 - 0.025 13.8 0.0 0.35 10.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Arylesterase PF01731.15 EJS44383.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Arylesterase Ank_4 PF13637.1 EJS44384.1 - 7.2e-15 55.0 0.1 1.5e-07 31.7 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EJS44384.1 - 7.7e-14 51.4 0.0 4.7e-05 23.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EJS44384.1 - 1.9e-12 47.3 0.0 2.8e-06 27.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EJS44384.1 - 9e-10 37.8 0.2 0.0032 17.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 EJS44384.1 - 6.3e-08 32.2 3.1 1.2e-07 31.3 0.2 2.9 2 1 0 2 2 2 1 KilA-N domain Ank_3 PF13606.1 EJS44384.1 - 4e-07 29.6 0.6 0.023 14.9 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat NTP_transferase PF00483.18 EJS44385.1 - 2.7e-50 171.0 0.0 3.5e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EJS44385.1 - 7.5e-11 42.3 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EJS44385.1 - 3.8e-09 35.6 7.5 4.8e-07 28.9 0.7 3.7 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EJS44385.1 - 0.0061 16.1 6.6 0.065 12.8 0.7 3.2 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 EJS44385.1 - 0.031 13.8 0.0 0.087 12.4 0.0 1.6 1 1 0 1 1 1 0 Cytidylyltransferase MFS_1 PF07690.11 EJS44386.1 - 1.2e-14 53.8 27.3 1.9e-14 53.1 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Acyltransferase PF01553.16 EJS44387.1 - 8.1e-35 119.1 0.0 1.1e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF3529 PF12046.3 EJS44387.1 - 0.14 11.1 0.4 0.36 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3529) zf-C2H2_6 PF13912.1 EJS44388.1 - 8.7e-05 22.2 12.2 0.00058 19.6 0.1 4.3 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EJS44388.1 - 0.00024 21.2 22.8 0.0015 18.7 1.2 5.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EJS44388.1 - 0.0011 19.1 1.8 0.0011 19.1 1.2 5.2 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EJS44388.1 - 0.0048 17.1 2.2 0.0048 17.1 1.5 4.8 4 1 1 5 5 5 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EJS44388.1 - 0.046 13.8 2.5 0.16 12.1 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.9 EJS44388.1 - 0.11 12.0 0.1 0.11 12.0 0.1 3.5 4 1 1 5 5 5 0 Rad50 zinc hook motif zf-Di19 PF05605.7 EJS44388.1 - 0.36 10.9 9.8 0.46 10.6 3.3 3.4 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_1 PF14446.1 EJS44388.1 - 0.97 9.2 6.2 16 5.3 0.4 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_3 PF14369.1 EJS44388.1 - 1 9.4 5.0 5 7.2 0.2 3.5 3 0 0 3 3 3 0 zinc-finger zf-RING_5 PF14634.1 EJS44388.1 - 1.4 8.7 7.5 14 5.5 0.1 3.4 3 0 0 3 3 3 0 zinc-RING finger domain zf-C2HC_2 PF13913.1 EJS44388.1 - 6 6.6 12.4 5.2 6.8 0.1 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.1 EJS44388.1 - 7.9 6.2 7.4 62 3.4 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EJS44388.1 - 8.5 6.0 7.5 56 3.4 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Metallophos PF00149.23 EJS44389.1 - 1.8e-43 148.2 0.2 2.3e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EJS44389.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DIL PF01843.14 EJS44389.1 - 0.12 12.2 0.1 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 DIL domain E1_DerP2_DerF2 PF02221.10 EJS44390.1 - 1.1e-26 93.6 0.0 1.2e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EJS44390.1 - 0.0024 17.9 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 ML-like domain CHCH PF06747.8 EJS44391.1 - 3.1e-05 23.7 0.2 4.2e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EJS44391.1 - 0.00073 19.2 0.2 0.00088 19.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CMV_US PF08001.6 EJS44391.1 - 0.036 13.1 0.0 0.039 12.9 0.0 1.0 1 0 0 1 1 1 0 CMV US SIR2 PF02146.12 EJS44393.1 - 2.7e-66 222.6 0.0 5.2e-66 221.7 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EJS44393.1 - 1.5e-62 209.7 0.4 3.2e-62 208.6 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EJS44393.1 - 0.0012 18.6 0.0 0.97 9.1 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain NARP1 PF12569.3 EJS44394.1 - 5.4e-116 388.3 21.7 6.9e-79 265.9 0.8 2.7 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 EJS44394.1 - 5.6e-11 42.6 5.7 0.03 14.6 0.0 5.5 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EJS44394.1 - 8.6e-11 41.4 1.2 0.93 10.3 0.0 7.5 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EJS44394.1 - 1.2e-10 40.4 6.4 0.11 12.5 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EJS44394.1 - 2.4e-10 40.7 1.7 0.035 14.7 0.0 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EJS44394.1 - 1.4e-08 34.2 12.7 0.0083 15.7 0.0 5.5 6 0 0 6 6 6 3 TPR repeat TPR_17 PF13431.1 EJS44394.1 - 6.4e-05 22.8 5.5 5.2 7.5 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EJS44394.1 - 0.015 15.2 9.8 0.31 10.9 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat FRG2 PF15315.1 EJS44394.1 - 0.021 14.7 5.4 0.037 14.0 2.9 1.9 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Fis1_TPR_C PF14853.1 EJS44394.1 - 0.064 13.1 8.6 0.53 10.1 0.2 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 EJS44394.1 - 0.39 10.6 13.2 12 5.9 0.0 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat DUF3602 PF12223.3 EJS44395.1 - 2e-17 63.3 26.1 5.1e-05 23.5 0.2 4.8 3 2 2 5 5 5 4 Protein of unknown function (DUF3602) Glu_synthase PF01645.12 EJS44396.1 - 2.6e-158 526.7 0.0 9.3e-158 524.9 0.0 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EJS44396.1 - 3.7e-138 460.1 0.0 5.6e-138 459.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EJS44396.1 - 3.9e-117 390.6 0.0 1.1e-116 389.1 0.0 1.8 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 EJS44396.1 - 4.5e-61 205.3 2.3 8e-61 204.5 1.6 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EJS44396.1 - 7.8e-24 83.4 0.0 1.5e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EJS44396.1 - 3.6e-12 46.6 0.0 2.8e-11 43.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EJS44396.1 - 1.9e-08 34.2 0.0 5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EJS44396.1 - 2.5e-08 34.2 1.2 2.9e-06 27.6 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EJS44396.1 - 3.8e-07 30.3 0.8 0.0045 17.0 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EJS44396.1 - 9.3e-06 24.9 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EJS44396.1 - 0.00043 19.2 0.2 0.0013 17.7 0.1 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EJS44396.1 - 0.00046 18.7 1.5 0.00051 18.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EJS44396.1 - 0.00082 18.5 0.1 0.007 15.4 0.0 2.4 3 0 0 3 3 2 1 Thi4 family FAD_binding_3 PF01494.14 EJS44396.1 - 0.0016 17.5 0.1 0.0029 16.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EJS44396.1 - 0.0026 16.9 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EJS44396.1 - 0.0027 16.6 0.2 0.005 15.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EJS44396.1 - 0.0032 16.6 0.0 0.059 12.5 0.0 2.7 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EJS44396.1 - 0.0063 16.2 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.1 EJS44396.1 - 0.015 15.2 0.0 0.046 13.6 0.0 1.9 1 1 0 1 1 1 0 Glutamine amidotransferase domain AlaDh_PNT_C PF01262.16 EJS44396.1 - 0.02 14.4 0.0 0.42 10.1 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 EJS44396.1 - 0.025 14.4 3.9 0.78 9.5 0.1 2.7 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.1 EJS44396.1 - 0.056 13.7 0.3 15 5.9 0.0 2.9 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EJS44396.1 - 0.061 12.9 2.0 0.084 12.5 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 EJS44396.1 - 0.074 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain GIDA PF01134.17 EJS44396.1 - 0.077 11.8 1.6 0.18 10.6 0.1 2.0 1 1 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EJS44396.1 - 0.11 12.5 1.8 15 5.7 0.1 3.1 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase FMN_dh PF01070.13 EJS44396.1 - 0.15 10.8 1.7 0.57 8.9 0.6 2.2 3 0 0 3 3 3 0 FMN-dependent dehydrogenase Fungal_trans_2 PF11951.3 EJS44397.1 - 8.5e-64 215.5 1.9 1e-63 215.2 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS44397.1 - 1.5e-08 34.3 8.1 2.6e-08 33.6 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EJS44397.1 - 0.4 10.8 6.5 0.81 9.8 4.5 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region ADH_N PF08240.7 EJS44398.1 - 3.4e-27 94.3 3.1 3.4e-27 94.3 2.2 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EJS44398.1 - 5.8e-22 77.6 0.1 1.2e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EJS44398.1 - 0.00045 21.0 0.0 0.0015 19.3 0.0 1.9 2 1 1 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EJS44398.1 - 0.0051 15.9 0.1 0.0084 15.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EJS44398.1 - 0.0098 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EJS44398.1 - 0.062 12.8 1.0 0.11 11.9 0.7 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AAA_18 PF13238.1 EJS44399.1 - 1.2e-26 93.5 0.1 1.7e-26 93.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EJS44399.1 - 3.4e-14 53.6 0.3 5.4e-14 53.0 0.2 1.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EJS44399.1 - 0.00015 21.9 0.3 0.00055 20.0 0.0 1.9 2 0 0 2 2 2 1 RNA helicase Cytidylate_kin2 PF13189.1 EJS44399.1 - 0.00045 20.1 0.5 0.0024 17.8 0.4 1.9 1 1 0 1 1 1 1 Cytidylate kinase-like family KTI12 PF08433.5 EJS44399.1 - 0.0011 18.2 0.0 0.011 15.0 0.0 2.0 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 EJS44399.1 - 0.0016 18.4 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EJS44399.1 - 0.0025 17.8 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.12 EJS44399.1 - 0.0029 17.0 0.1 0.54 9.6 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_14 PF13173.1 EJS44399.1 - 0.0035 17.2 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EJS44399.1 - 0.0048 17.1 0.0 0.0072 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EJS44399.1 - 0.0077 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EJS44399.1 - 0.01 15.9 0.1 0.019 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EJS44399.1 - 0.013 15.4 0.1 2.9 7.7 0.0 2.3 1 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EJS44399.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ADK PF00406.17 EJS44399.1 - 0.088 12.6 0.1 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase NTPase_1 PF03266.10 EJS44399.1 - 0.1 12.2 0.1 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 EJS44399.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NOT2_3_5 PF04153.13 EJS44400.1 - 6.1e-34 116.7 0.9 7.2e-34 116.5 0.7 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Imm43 PF15602.1 EJS44400.1 - 0.069 13.1 0.1 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 43 DNA_ligase_A_M PF01068.16 EJS44401.1 - 2.3e-61 206.7 0.4 3.6e-61 206.0 0.3 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EJS44401.1 - 5.6e-55 185.8 0.5 1.1e-54 184.9 0.4 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EJS44401.1 - 4.3e-26 91.1 0.0 1.4e-25 89.4 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EJS44401.1 - 0.0063 16.1 0.8 1.7 8.3 0.0 2.6 2 0 0 2 2 2 2 DNA ligase OB-like domain ENTH PF01417.15 EJS44402.1 - 1.4e-41 141.2 0.5 3.5e-41 139.9 0.4 1.7 1 0 0 1 1 1 1 ENTH domain SAM_adeno_trans PF01887.11 EJS44402.1 - 0.18 10.8 1.1 0.36 9.8 0.3 1.8 2 0 0 2 2 2 0 S-adenosyl-l-methionine hydroxide adenosyltransferase DUF4412 PF14371.1 EJS44402.1 - 9 6.8 7.7 1.8 9.1 1.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4412) CENP-X PF09415.5 EJS44403.1 - 1.2e-20 73.1 0.0 1.3e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X DEAD PF00270.24 EJS44404.1 - 7.9e-42 142.6 0.1 1.3e-41 141.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EJS44404.1 - 1.1e-25 89.2 0.1 2.5e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EJS44404.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain WD40 PF00400.27 EJS44406.1 - 2.1e-12 46.4 2.8 0.0016 18.2 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Cyclin_N PF00134.18 EJS44407.1 - 4.5e-44 149.0 1.2 5.9e-44 148.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EJS44407.1 - 3.2e-25 88.3 0.1 6.7e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain MutS_V PF00488.16 EJS44408.1 - 3.7e-56 190.1 0.1 6.4e-56 189.3 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EJS44408.1 - 4.4e-26 91.9 0.3 4.4e-26 91.9 0.2 1.9 2 1 0 2 2 2 1 MutS domain III AAA_29 PF13555.1 EJS44408.1 - 0.019 14.4 0.1 0.047 13.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EJS44408.1 - 0.14 12.0 4.3 0.41 10.5 0.1 3.7 4 0 0 4 4 4 0 AAA domain Sas10 PF09368.5 EJS44409.1 - 1.2e-29 102.2 11.1 1.2e-29 102.2 7.7 2.4 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EJS44409.1 - 4.5e-10 39.5 0.1 2e-09 37.5 0.0 2.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family APG9 PF04109.11 EJS44410.1 - 2.6e-164 546.5 6.2 3.6e-164 546.0 4.3 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 Nop14 PF04147.7 EJS44411.1 - 1.9e-228 760.5 77.7 3.2e-135 452.1 11.3 2.0 1 1 1 2 2 2 2 Nop14-like family PCI PF01399.22 EJS44412.1 - 6.2e-23 81.1 3.8 1.2e-22 80.1 0.2 2.8 2 0 0 2 2 2 1 PCI domain MinC_N PF05209.8 EJS44412.1 - 0.086 12.6 2.9 11 5.8 0.0 3.5 3 1 0 3 3 3 0 Septum formation inhibitor MinC, N-terminal domain DUF2013 PF09431.5 EJS44413.1 - 5.7e-46 155.7 9.4 5.7e-46 155.7 6.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Coatomer_WDAD PF04053.9 EJS44414.1 - 1.5e-138 462.3 1.5 2.2e-138 461.7 1.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EJS44414.1 - 7.7e-70 235.5 0.0 1.2e-69 234.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EJS44414.1 - 1.4e-57 189.6 13.7 4.1e-10 39.1 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EJS44414.1 - 5.7e-07 29.4 0.3 0.0065 16.2 0.0 3.8 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EJS44414.1 - 3.8e-06 25.3 6.0 0.1 10.6 0.3 3.7 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EJS44414.1 - 0.029 13.8 0.1 1.4 8.4 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ApbA_C PF08546.6 EJS44415.1 - 5.3e-27 94.2 0.0 9.1e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EJS44415.1 - 7.9e-20 70.8 0.0 1.2e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EJS44415.1 - 0.035 14.5 0.1 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cpn60_TCP1 PF00118.19 EJS44416.1 - 1.2e-133 446.2 12.1 1.5e-133 445.9 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 EJS44416.1 - 0.057 12.7 2.1 0.9 8.7 0.1 2.9 3 0 0 3 3 3 0 DeoC/LacD family aldolase BPL_N PF09825.4 EJS44417.1 - 2e-139 464.5 0.0 2.5e-139 464.1 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EJS44417.1 - 2e-17 63.3 0.1 2e-16 60.1 0.0 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EJS44417.1 - 7.1e-15 54.4 0.0 1.6e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain RNA_pol_Rpb1_1 PF04997.7 EJS44418.1 - 7.7e-120 400.1 0.0 1.3e-119 399.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EJS44418.1 - 5.8e-108 360.3 0.1 1e-107 359.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EJS44418.1 - 2.6e-72 242.1 0.0 7.3e-72 240.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EJS44418.1 - 2.6e-63 213.1 0.4 5.6e-63 212.0 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EJS44418.1 - 3.5e-47 160.0 0.0 9.9e-47 158.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EJS44418.1 - 7.1e-45 152.0 3.2 1.7e-44 150.7 2.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EJS44418.1 - 2.1e-35 120.7 0.1 5.8e-35 119.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EJS44418.1 - 2.1e-17 61.6 277.9 0.032 14.3 8.6 14.9 2 1 11 20 20 20 17 RNA polymerase Rpb1 C-terminal repeat NAC PF01849.13 EJS44418.1 - 1.1 8.7 4.3 22 4.6 0.7 2.6 2 0 0 2 2 2 0 NAC domain Scm3 PF10384.4 EJS44419.1 - 1.3e-21 75.8 1.0 1.3e-21 75.8 0.7 2.4 3 0 0 3 3 3 1 Centromere protein Scm3 Arf PF00025.16 EJS44420.1 - 4.2e-78 260.5 0.0 4.8e-78 260.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EJS44420.1 - 2e-14 53.2 0.0 2.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EJS44420.1 - 1.1e-13 50.8 0.0 1.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EJS44420.1 - 3.1e-11 42.8 0.0 3.7e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EJS44420.1 - 1.2e-10 40.6 0.5 1.4e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EJS44420.1 - 1.8e-10 41.3 0.0 2.4e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EJS44420.1 - 9.3e-06 25.5 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.17 EJS44420.1 - 0.0059 16.0 0.2 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 EJS44420.1 - 0.0069 15.8 0.0 0.033 13.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EJS44420.1 - 0.008 16.0 0.1 0.012 15.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EJS44420.1 - 0.0085 15.7 0.5 1 8.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 EJS44420.1 - 0.034 14.4 0.1 0.065 13.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.13 EJS44420.1 - 0.037 13.0 0.1 0.06 12.4 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.14 EJS44420.1 - 0.087 12.2 0.1 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EJS44420.1 - 0.16 12.1 0.2 0.64 10.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain Rho_GDI PF02115.12 EJS44421.1 - 8.2e-70 234.2 2.7 8.9e-70 234.1 1.9 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 EJS44422.1 - 9.2e-40 136.1 0.7 1.3e-39 135.6 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L41 PF05162.8 EJS44423.1 - 3.4e-09 36.1 25.8 3.6e-09 36.1 17.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1601 PF07671.6 EJS44423.1 - 0.25 10.9 1.7 0.28 10.8 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1601) Cullin PF00888.17 EJS44424.1 - 1.1e-167 559.2 17.1 1.4e-167 558.7 11.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EJS44424.1 - 2.7e-25 87.9 0.1 1e-24 86.1 0.1 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Phage_rep_O PF04492.8 EJS44424.1 - 0.0056 16.8 0.9 1.6 8.9 0.0 3.4 3 0 0 3 3 3 1 Bacteriophage replication protein O Penicillinase_R PF03965.11 EJS44424.1 - 0.029 14.4 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 0 Penicillinase repressor IATP PF04568.7 EJS44425.1 - 3.5e-22 78.2 0.5 3.7e-22 78.2 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Fib_alpha PF08702.5 EJS44425.1 - 0.0027 17.8 0.8 0.003 17.7 0.6 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Atg14 PF10186.4 EJS44425.1 - 0.024 13.5 0.8 0.021 13.7 0.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 EJS44425.1 - 0.051 13.0 3.8 0.07 12.6 2.6 1.3 1 0 0 1 1 1 0 Septum formation initiator MCRS_N PF13325.1 EJS44425.1 - 0.054 13.0 0.7 0.059 12.8 0.5 1.1 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein DUF1352 PF07086.7 EJS44425.1 - 0.091 12.3 0.1 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) Bap31 PF05529.7 EJS44425.1 - 0.093 12.1 0.3 0.084 12.3 0.2 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PspB PF06667.7 EJS44425.1 - 0.1 12.5 2.1 0.14 12.0 1.5 1.1 1 0 0 1 1 1 0 Phage shock protein B XhlA PF10779.4 EJS44425.1 - 0.14 12.0 1.7 0.17 11.7 1.2 1.2 1 0 0 1 1 1 0 Haemolysin XhlA DUF4140 PF13600.1 EJS44425.1 - 0.14 12.5 0.7 0.19 12.2 0.5 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ABC_tran_2 PF12848.2 EJS44425.1 - 0.17 11.7 4.9 0.22 11.3 3.4 1.3 1 0 0 1 1 1 0 ABC transporter Cnl2_NKP2 PF09447.5 EJS44425.1 - 0.17 11.5 1.7 0.27 10.9 1.1 1.4 1 0 0 1 1 1 0 Cnl2/NKP2 family protein DUF1366 PF07104.6 EJS44425.1 - 0.25 10.9 2.2 0.32 10.6 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) DUF1049 PF06305.6 EJS44425.1 - 0.44 10.0 2.4 0.62 9.5 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF3813 PF12758.2 EJS44425.1 - 0.57 10.3 4.3 1 9.5 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Pox_A_type_inc PF04508.7 EJS44425.1 - 1.5 8.7 9.6 1.9 8.4 0.8 2.5 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat FAD-oxidase_C PF02913.14 EJS44427.1 - 1.3e-60 204.7 0.0 1.7e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EJS44427.1 - 1.2e-33 115.5 0.1 2.3e-33 114.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain UPF0029 PF01205.14 EJS44428.1 - 1.9e-35 120.8 0.5 3.3e-35 120.0 0.4 1.4 1 1 0 1 1 1 1 Uncharacterized protein family UPF0029 DDE_Tnp_1_7 PF13843.1 EJS44428.1 - 0.014 14.4 1.9 0.019 14.0 1.3 1.1 1 0 0 1 1 1 0 Transposase IS4 TraH_2 PF06871.6 EJS44428.1 - 0.02 14.3 0.3 1.9 7.9 0.0 2.1 1 1 0 2 2 2 0 TraH_2 APC8 PF04049.8 EJS44428.1 - 0.089 12.5 1.5 0.12 12.1 1.1 1.1 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 YwqJ-deaminase PF14431.1 EJS44428.1 - 0.11 12.4 0.9 0.14 11.9 0.7 1.2 1 0 0 1 1 1 0 YwqJ-like deaminase DUF2615 PF11027.3 EJS44428.1 - 0.19 11.6 1.6 0.51 10.2 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) zf-CCHC PF00098.18 EJS44430.1 - 4.1e-07 29.6 16.7 6.5e-05 22.6 3.4 5.6 5 1 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.1 EJS44430.1 - 3.1 7.5 25.6 0.37 10.5 0.2 4.1 2 1 1 3 3 3 0 Zinc knuckle FAD-oxidase_C PF02913.14 EJS44431.1 - 2e-56 191.1 0.1 2.6e-56 190.6 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EJS44431.1 - 1.1e-35 122.1 0.0 5.8e-35 119.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Hom_end_hint PF05203.11 EJS44432.1 - 1.9e-47 161.7 0.0 2.3e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.9 EJS44432.1 - 3e-45 152.6 0.0 1.1e-38 131.6 0.0 2.4 2 0 0 2 2 2 2 Homing endonuclease LAGLIDADG_3 PF14528.1 EJS44432.1 - 1.3e-09 38.1 0.0 5.7e-06 26.4 0.0 3.2 3 1 0 3 3 3 2 LAGLIDADG-like domain DUF1794 PF08768.6 EJS44432.1 - 0.061 13.1 0.2 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1794) RPAP1_N PF08621.5 EJS44432.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal ArfGap PF01412.13 EJS44433.1 - 1.1e-32 112.2 0.0 2.6e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Septin PF00735.13 EJS44434.1 - 3e-72 243.0 8.8 5.4e-67 225.7 1.4 2.5 3 0 0 3 3 3 2 Septin AAA_33 PF13671.1 EJS44434.1 - 0.0005 19.9 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EJS44434.1 - 0.0048 17.0 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EJS44434.1 - 0.0051 17.6 0.7 0.036 14.8 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 EJS44434.1 - 0.0071 16.6 5.5 0.065 13.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EJS44434.1 - 0.011 14.6 1.7 0.017 14.0 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.24 EJS44434.1 - 0.02 15.0 1.8 0.027 14.6 0.0 2.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Synaptobrevin PF00957.16 EJS44434.1 - 0.024 14.2 1.0 0.089 12.4 0.7 1.9 1 0 0 1 1 1 0 Synaptobrevin RNA_helicase PF00910.17 EJS44434.1 - 0.031 14.4 0.0 0.099 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EJS44434.1 - 0.066 12.4 0.1 0.24 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MobB PF03205.9 EJS44434.1 - 0.071 12.8 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EJS44434.1 - 0.082 12.3 0.0 0.52 9.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EJS44434.1 - 0.098 12.4 0.0 0.098 12.4 0.0 3.3 2 2 0 2 2 1 0 Dynamin family IstB_IS21 PF01695.12 EJS44434.1 - 0.12 11.7 0.1 0.28 10.5 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EJS44434.1 - 0.16 11.4 0.0 0.16 11.4 0.0 2.2 3 1 0 3 3 3 0 FtsK/SpoIIIE family RRM_1 PF00076.17 EJS44435.1 - 3.8e-17 61.6 0.0 2e-13 49.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS44435.1 - 2.3e-08 33.8 0.0 9.2e-07 28.7 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SUR7 PF06687.7 EJS44437.1 - 3.6e-42 144.3 8.7 4.3e-42 144.0 6.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EJS44437.1 - 1.2e-05 25.0 5.6 1.2e-05 25.0 3.9 1.7 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Fig1 PF12351.3 EJS44437.1 - 0.00011 22.1 9.1 0.00018 21.4 6.3 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 ABC2_membrane_4 PF12730.2 EJS44437.1 - 0.043 12.9 16.0 0.16 11.0 5.8 2.9 3 0 0 3 3 3 0 ABC-2 family transporter protein Tetraspannin PF00335.15 EJS44437.1 - 8.3 5.6 17.1 2.7 7.1 3.3 2.8 2 1 0 2 2 2 0 Tetraspanin family MARVEL PF01284.18 EJS44438.1 - 3.1e-26 91.9 14.7 4.9e-26 91.2 10.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain Penaeidin PF05927.6 EJS44438.1 - 0.011 16.2 0.2 0.024 15.1 0.2 1.6 1 0 0 1 1 1 0 Penaeidin DUF4184 PF13803.1 EJS44438.1 - 0.057 12.7 2.2 0.11 11.7 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) PepSY_TM_3 PF13706.1 EJS44438.1 - 0.65 9.4 0.0 0.65 9.4 0.0 3.9 5 1 0 5 5 5 0 PepSY-associated TM helix Tic20 PF09685.5 EJS44438.1 - 4.8 7.2 9.5 3.2 7.7 4.0 2.1 2 0 0 2 2 2 0 Tic20-like protein Tim17 PF02466.14 EJS44439.1 - 6.9e-45 152.2 12.4 1.2e-44 151.4 8.6 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.13 EJS44439.1 - 0.027 13.7 0.2 0.29 10.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family JAB PF01398.16 EJS44440.1 - 3.1e-29 101.0 0.0 7.8e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EJS44440.1 - 3.9e-05 23.1 0.0 8.5e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain ELFV_dehydrog PF00208.16 EJS44441.1 - 1.7e-60 204.6 0.0 3.8e-60 203.4 0.0 1.6 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EJS44441.1 - 2e-17 62.0 4.6 4.8e-12 44.2 0.2 2.7 2 1 1 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EJS44441.1 - 0.023 14.2 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain RRM_1 PF00076.17 EJS44442.1 - 7.4e-05 22.3 0.0 0.00016 21.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS44442.1 - 0.00078 19.3 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SHR3_chaperone PF08229.6 EJS44443.1 - 8.4e-82 272.8 0.2 9.8e-82 272.6 0.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 BPD_transp_2 PF02653.11 EJS44443.1 - 3.8e-05 22.7 0.4 4.6e-05 22.5 0.3 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF1049 PF06305.6 EJS44443.1 - 0.0026 17.1 0.4 0.86 9.1 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1049) Tetraspannin PF00335.15 EJS44443.1 - 0.007 15.6 1.7 0.42 9.8 1.2 2.1 1 1 1 2 2 2 1 Tetraspanin family YiaAB PF05360.9 EJS44443.1 - 1.4 8.5 8.6 1.3 8.6 0.1 2.8 3 0 0 3 3 3 0 yiaA/B two helix domain Romo1 PF10247.4 EJS44444.1 - 0.0025 17.9 0.7 0.0046 17.1 0.5 1.4 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Protocadherin PF08374.6 EJS44444.1 - 0.052 13.1 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 Protocadherin Syndecan PF01034.15 EJS44444.1 - 0.056 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Podoplanin PF05808.6 EJS44444.1 - 0.92 9.0 10.3 0.089 12.3 3.8 1.9 2 1 0 2 2 2 0 Podoplanin AA_permease_2 PF13520.1 EJS44445.1 - 1.5e-64 218.1 42.1 1.8e-64 217.8 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EJS44445.1 - 1.5e-22 79.5 36.3 2e-22 79.1 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease Renin_r PF07850.9 EJS44445.1 - 2.5 8.5 4.4 11 6.4 0.5 3.3 3 0 0 3 3 3 0 Renin receptor-like protein RRM_1 PF00076.17 EJS44446.1 - 2.4e-07 30.3 0.2 5.6e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS44446.1 - 8.3e-06 25.5 0.1 1.8e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS44446.1 - 0.0052 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EJS44446.1 - 0.018 14.8 0.2 0.037 13.8 0.1 1.6 1 1 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.1 EJS44446.1 - 0.046 13.5 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EJS44446.1 - 1.1 9.0 4.6 1.9 8.2 3.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GLE1 PF07817.8 EJS44447.1 - 6.6e-90 300.4 0.0 6.6e-90 300.4 0.0 2.7 2 1 0 3 3 3 1 GLE1-like protein SprA-related PF12118.3 EJS44447.1 - 0.0016 17.8 16.1 0.0024 17.2 11.2 1.3 1 0 0 1 1 1 1 SprA-related family CAF-1_p150 PF11600.3 EJS44447.1 - 0.0022 17.3 44.3 0.0022 17.3 30.7 1.6 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hom_end_hint PF05203.11 EJS44447.1 - 0.073 12.7 3.7 0.098 12.3 2.6 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Ycf1 PF05758.7 EJS44447.1 - 0.49 8.0 22.4 0.68 7.5 15.5 1.3 1 0 0 1 1 1 0 Ycf1 LMBR1 PF04791.11 EJS44447.1 - 1.4 7.4 6.8 1.9 6.9 4.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4613 PF15390.1 EJS44447.1 - 2.9 5.9 16.9 4 5.4 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Macoilin PF09726.4 EJS44447.1 - 3.1 5.9 30.1 4.6 5.3 20.9 1.3 1 0 0 1 1 1 0 Transmembrane protein Asp-B-Hydro_N PF05279.6 EJS44447.1 - 3.6 7.3 25.7 6 6.6 17.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Porphobil_deam PF01379.15 EJS44448.1 - 3.3e-90 300.7 0.0 4.5e-90 300.2 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EJS44448.1 - 2.2e-21 75.6 0.9 3.8e-21 74.9 0.6 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Reticulon PF02453.12 EJS44449.1 - 5.8e-33 113.8 0.8 8.7e-33 113.3 0.5 1.3 1 0 0 1 1 1 1 Reticulon Sel1 PF08238.7 EJS44450.1 - 1.7e-32 111.0 21.2 9.7e-07 29.2 0.0 7.7 7 1 0 7 7 7 7 Sel1 repeat Ribosomal_L10 PF00466.15 EJS44451.1 - 5.9e-11 42.1 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Methyltransf_4 PF02390.12 EJS44452.1 - 3.7e-62 208.8 0.2 5.1e-62 208.4 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EJS44452.1 - 1.4e-05 24.6 0.1 3.1e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS44452.1 - 4.4e-05 24.0 0.0 6.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EJS44452.1 - 0.00048 20.1 0.0 0.0008 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EJS44452.1 - 0.0016 17.8 0.0 0.0034 16.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EJS44452.1 - 0.0039 17.5 0.0 0.0083 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EJS44452.1 - 0.019 14.1 0.0 0.06 12.4 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EJS44452.1 - 0.023 15.1 0.0 0.065 13.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF3958 PF13125.1 EJS44452.1 - 0.11 12.3 0.3 0.11 12.3 0.2 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) DOT1 PF08123.8 EJS44452.1 - 0.11 11.7 0.0 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Histone methylation protein DOT1 Sugar_tr PF00083.19 EJS44453.1 - 1.3e-38 132.7 30.1 1.6e-38 132.4 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS44453.1 - 2.4e-11 42.9 31.9 2.1e-10 39.8 19.2 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily Mito_carr PF00153.22 EJS44454.1 - 1e-31 108.5 0.1 1.5e-14 53.4 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Sec31 PF11549.3 EJS44455.1 - 4.5e-27 93.4 5.9 5.6e-27 93.1 1.6 2.8 2 0 0 2 2 2 1 Protein transport protein SEC31 WD40 PF00400.27 EJS44455.1 - 2.7e-20 71.4 11.2 9.4e-06 25.3 0.0 8.1 8 0 0 8 8 8 4 WD domain, G-beta repeat SRA1 PF07304.6 EJS44455.1 - 4.5e-07 29.7 3.3 1.1e-06 28.4 0.3 2.9 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EJS44455.1 - 2.3e-05 24.2 3.4 8.5e-05 22.4 2.4 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Arf PF00025.16 EJS44456.1 - 1e-77 259.2 0.0 1.2e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EJS44456.1 - 2.7e-14 52.8 0.0 2.9e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EJS44456.1 - 2.5e-13 49.6 0.0 3e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EJS44456.1 - 1.9e-11 43.5 0.0 2.3e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EJS44456.1 - 4.8e-11 41.9 0.4 5.3e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EJS44456.1 - 2.1e-10 41.0 0.0 2.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EJS44456.1 - 6.6e-06 26.0 0.0 9.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 EJS44456.1 - 0.0055 16.3 0.4 0.69 9.5 0.0 2.1 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.17 EJS44456.1 - 0.006 16.0 0.2 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 EJS44456.1 - 0.0061 16.0 0.0 0.029 13.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EJS44456.1 - 0.0082 16.0 0.1 0.012 15.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EJS44456.1 - 0.033 13.6 0.1 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EJS44456.1 - 0.037 14.3 0.1 0.069 13.4 0.1 1.5 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.13 EJS44456.1 - 0.045 12.8 0.1 0.06 12.4 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DBD_Tnp_Mut PF03108.10 EJS44456.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 MuDR family transposase Ufd2P_core PF10408.4 EJS44457.1 - 9.4e-187 622.0 4.6 9.4e-187 622.0 3.2 1.8 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.10 EJS44457.1 - 8.3e-28 96.1 1.4 2.8e-27 94.4 0.9 2.0 1 0 0 1 1 1 1 U-box domain Metallophos PF00149.23 EJS44458.1 - 4.1e-39 134.0 0.6 4.1e-39 134.0 0.4 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TSA PF03249.8 EJS44459.1 - 0.021 13.3 1.0 0.028 12.9 0.7 1.1 1 0 0 1 1 1 0 Type specific antigen Fimbrial_PilY2 PF14481.1 EJS44459.1 - 0.24 10.8 1.7 0.47 9.8 0.6 1.8 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 Med3 PF11593.3 EJS44459.1 - 0.45 9.7 5.9 0.65 9.1 4.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L41 PF05162.8 EJS44460.1 - 3.4e-09 36.1 25.8 3.6e-09 36.1 17.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1601 PF07671.6 EJS44460.1 - 0.25 10.9 1.7 0.28 10.8 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1601) Alpha-amylase PF00128.19 EJS44461.1 - 1.4e-109 366.2 0.7 1.9e-109 365.9 0.0 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EJS44461.1 - 0.0093 16.0 0.1 0.041 14.0 0.1 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.1 EJS44461.1 - 0.015 14.2 0.0 0.071 11.9 0.0 1.9 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme DUF4434 PF14488.1 EJS44461.1 - 0.032 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) RNA_POL_M_15KD PF02150.11 EJS44461.1 - 0.18 11.5 1.6 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit LIM PF00412.17 EJS44462.1 - 2.9e-39 132.9 50.8 8e-16 57.8 3.3 4.6 4 0 0 4 4 4 4 LIM domain RhoGAP PF00620.22 EJS44462.1 - 3.5e-36 124.1 0.1 1.1e-35 122.5 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain SID PF11778.3 EJS44463.1 - 2.8e-46 156.8 1.3 2.8e-46 156.8 0.9 2.8 2 1 0 2 2 2 1 Septation initiation DUF2360 PF10152.4 EJS44463.1 - 0.18 12.0 8.1 2 8.7 0.7 2.9 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Reo_sigmaC PF04582.7 EJS44463.1 - 5.3 6.1 8.7 24 3.9 0.4 3.2 3 0 0 3 3 3 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EJS44463.1 - 7.6 4.8 60.2 0.051 12.0 17.5 2.8 2 1 0 2 2 2 0 AAA domain Hpt PF01627.18 EJS44465.1 - 1.6e-12 47.2 0.1 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Hpt domain PHB_acc PF05233.8 EJS44465.1 - 0.046 13.4 0.2 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 PHB accumulation regulatory domain RabGAP-TBC PF00566.13 EJS44466.1 - 2.1e-31 109.0 6.5 2.1e-31 109.0 4.5 3.9 4 1 1 5 5 5 2 Rab-GTPase-TBC domain LIM_bind PF01803.11 EJS44467.1 - 2.1e-52 177.6 0.3 2.1e-52 177.6 0.2 1.5 2 0 0 2 2 2 1 LIM-domain binding protein Ost4 PF10215.4 EJS44468.1 - 1.2e-16 59.9 0.7 1.2e-16 59.8 0.5 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase SK_channel PF03530.9 EJS44468.1 - 0.061 13.1 0.1 0.061 13.1 0.1 1.1 1 0 0 1 1 1 0 Calcium-activated SK potassium channel FUSC_2 PF13515.1 EJS44469.1 - 5.3e-09 36.0 7.7 5.3e-09 36.0 5.4 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2422 PF10337.4 EJS44469.1 - 3.2e-06 26.2 3.9 3.2e-06 26.2 2.7 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EJS44469.1 - 0.00018 21.2 0.0 0.00049 19.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EJS44469.1 - 0.0013 17.4 3.6 0.088 11.4 0.1 3.4 3 0 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.7 EJS44469.1 - 0.002 16.6 7.0 0.07 11.5 0.0 2.4 2 1 0 2 2 2 2 Fusaric acid resistance protein family Y_phosphatase PF00102.22 EJS44470.1 - 1.7e-55 187.8 2.7 6.2e-55 186.0 1.9 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EJS44470.1 - 5e-05 22.8 0.0 9.4e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EJS44470.1 - 0.0004 20.6 0.0 0.00084 19.6 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EJS44470.1 - 0.0011 18.9 0.1 0.0038 17.2 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Myotub-related PF06602.9 EJS44470.1 - 0.089 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Hexapep PF00132.19 EJS44471.1 - 4.1e-15 54.5 15.8 1.1e-10 40.4 5.8 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EJS44471.1 - 2.2e-12 46.7 0.1 3.2e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EJS44471.1 - 3.5e-11 42.4 12.0 1.8e-08 33.7 3.7 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4485 PF14846.1 EJS44471.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) MinC_C PF03775.11 EJS44471.1 - 0.4 10.3 4.4 1.5 8.4 0.6 2.4 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain DUF1349 PF07081.6 EJS44472.1 - 1.6e-69 232.9 0.1 1.8e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) DUF866 PF05907.8 EJS44473.1 - 1.4e-27 96.1 6.7 2.3e-15 56.4 0.7 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) DUF581 PF04570.9 EJS44473.1 - 0.0083 15.3 0.5 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF581) zf-CHY PF05495.7 EJS44473.1 - 0.41 10.8 2.7 1.4 9.1 1.9 2.0 1 1 0 1 1 1 0 CHY zinc finger Elf1 PF05129.8 EJS44473.1 - 2 8.1 5.9 6.3 6.5 0.4 2.9 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Pkinase PF00069.20 EJS44474.1 - 6e-76 255.0 0.1 1.1e-75 254.1 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44474.1 - 6.3e-34 117.2 0.1 2e-33 115.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS44474.1 - 6.3e-13 48.3 0.0 1.2e-09 37.5 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EJS44474.1 - 0.028 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCR_beta PF02241.13 EJS44474.1 - 0.072 12.3 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain CDC50 PF03381.10 EJS44475.1 - 3.5e-101 338.0 2.1 4.2e-101 337.7 1.5 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Y_phosphatase2 PF03162.8 EJS44476.1 - 1.6e-47 160.9 4.4 2.2e-37 127.9 2.0 2.4 1 1 1 2 2 2 2 Tyrosine phosphatase family Transpep_BrtH PF14399.1 EJS44476.1 - 0.089 12.0 0.0 14 4.8 0.0 2.3 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase G10 PF01125.12 EJS44477.1 - 3e-60 201.9 8.5 3.4e-60 201.8 5.9 1.0 1 0 0 1 1 1 1 G10 protein DNase_II PF03265.10 EJS44477.1 - 0.014 14.4 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Deoxyribonuclease II zf-C3HC4 PF00097.20 EJS44478.1 - 2e-10 40.1 12.4 2e-10 40.1 8.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EJS44478.1 - 2.2e-08 33.9 12.5 2.2e-08 33.9 8.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EJS44478.1 - 1.2e-07 31.4 16.1 4.4e-07 29.6 8.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EJS44478.1 - 6.9e-07 28.8 13.0 2.7e-06 26.9 5.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 EJS44478.1 - 7.2e-07 28.5 0.0 2e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 SAP domain zf-RING_5 PF14634.1 EJS44478.1 - 1.6e-06 27.7 17.9 9.9e-06 25.1 7.6 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_6 PF14835.1 EJS44478.1 - 3.7e-06 26.6 3.9 3.7e-06 26.6 2.7 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EJS44478.1 - 6.8e-06 25.8 16.6 6.9e-06 25.8 8.3 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.10 EJS44478.1 - 0.00043 20.1 0.0 0.0031 17.4 0.0 2.5 3 0 0 3 3 3 1 U-box domain zf-RING_UBOX PF13445.1 EJS44478.1 - 0.0023 17.5 10.3 0.0023 17.5 7.1 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EJS44478.1 - 0.0077 16.3 9.7 0.0086 16.1 4.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger Baculo_IE-1 PF05290.6 EJS44478.1 - 0.021 14.5 3.1 0.044 13.5 1.0 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) GAGA PF09237.6 EJS44478.1 - 0.026 14.0 0.7 0.026 14.0 0.5 2.4 2 0 0 2 2 2 0 GAGA factor zf-RING_4 PF14570.1 EJS44478.1 - 0.15 11.6 8.4 0.25 10.9 1.8 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EJS44478.1 - 1.3 8.6 10.5 0.59 9.7 3.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EJS44478.1 - 1.5 8.7 5.4 9.9 6.0 1.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Lipase_3 PF01764.20 EJS44479.1 - 1.6e-09 37.4 0.0 3.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 EJS44479.1 - 0.03 14.0 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.2 EJS44479.1 - 0.044 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EJS44479.1 - 0.063 13.0 0.0 0.32 10.7 0.0 2.1 1 1 1 3 3 3 0 Alpha/beta hydrolase family Pro_isomerase PF00160.16 EJS44480.1 - 8.3e-22 78.0 0.0 1.5e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Img2 PF05046.9 EJS44481.1 - 9e-29 99.5 0.5 1.2e-28 99.1 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 EJS44481.1 - 0.024 14.4 0.8 0.19 11.5 0.5 2.1 1 1 0 1 1 1 0 Translation initiation factor SUI1 DUF3294 PF07957.6 EJS44481.1 - 0.049 13.1 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) WD40 PF00400.27 EJS44482.1 - 1.1e-84 275.5 35.5 2.6e-15 55.5 0.2 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EJS44482.1 - 5.4e-10 39.3 1.1 8.5e-05 22.3 0.0 3.8 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EJS44482.1 - 8.7e-07 27.4 12.9 0.13 10.3 0.4 5.8 2 2 4 6 6 6 3 Nucleoporin Nup120/160 NLE PF08154.7 EJS44482.1 - 4.1e-05 23.4 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nbas_N PF15492.1 EJS44482.1 - 0.00079 18.6 1.0 0.72 8.9 0.1 3.2 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EJS44482.1 - 0.0019 16.5 0.0 0.12 10.6 0.0 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain PD40 PF07676.7 EJS44482.1 - 0.0086 15.7 0.1 2.6 7.7 0.0 3.1 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 EJS44482.1 - 0.013 15.2 0.1 7.1 6.4 0.0 4.3 3 2 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Gmad1 PF10647.4 EJS44482.1 - 0.02 14.3 0.2 0.086 12.2 0.0 1.9 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain TFIIIC_delta PF12657.2 EJS44482.1 - 3.9 7.1 8.1 17 5.0 1.3 3.8 2 2 1 3 3 3 0 Transcription factor IIIC subunit delta N-term PQ-loop PF04193.9 EJS44483.1 - 1.4e-23 82.2 20.1 1.2e-13 50.3 0.6 3.3 2 1 1 3 3 3 2 PQ loop repeat DUF3215 PF11503.3 EJS44484.1 - 1e-29 101.9 0.1 1e-29 101.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) PI31_Prot_C PF08577.6 EJS44485.1 - 1.5e-11 44.7 11.7 4.2e-11 43.3 7.1 2.1 2 0 0 2 2 2 1 PI31 proteasome regulator PAT1 PF09770.4 EJS44486.1 - 3.2e-239 796.3 36.6 8.7e-237 788.3 25.4 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 PP2C PF00481.16 EJS44487.1 - 3.6e-42 144.5 0.0 1.2e-41 142.7 0.0 1.8 1 1 1 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 EJS44487.1 - 2.1e-06 27.3 0.0 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Med12 PF09497.5 EJS44488.1 - 7.9e-21 73.8 0.1 2.2e-20 72.3 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 PP1_inhibitor PF05361.7 EJS44489.1 - 0.006 16.2 0.9 0.0095 15.6 0.6 1.4 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Thioredoxin PF00085.15 EJS44490.1 - 7.8e-29 99.4 0.1 9.5e-29 99.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EJS44490.1 - 1.2e-07 31.9 0.6 6.4e-07 29.5 0.4 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EJS44490.1 - 1.6e-06 28.0 0.1 3.9e-05 23.6 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 EJS44490.1 - 0.00033 20.3 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EJS44490.1 - 0.00063 19.3 0.0 0.0007 19.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EJS44490.1 - 0.002 17.6 0.1 0.0084 15.6 0.1 1.6 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 EJS44490.1 - 0.0037 17.2 0.1 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.11 EJS44490.1 - 0.006 15.3 0.0 0.0067 15.1 0.0 1.0 1 0 0 1 1 1 1 Phosducin DSBA PF01323.15 EJS44490.1 - 0.009 15.5 0.2 0.19 11.2 0.1 2.0 1 1 1 2 2 2 1 DSBA-like thioredoxin domain NAPRTase PF04095.11 EJS44490.1 - 0.042 13.1 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family WD40 PF00400.27 EJS44491.1 - 4.8e-63 206.9 14.2 3.4e-10 39.3 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EJS44491.1 - 3.6e-30 103.9 12.8 3.6e-30 103.9 8.9 2.6 2 0 0 2 2 2 1 Tup N-terminal Nup160 PF11715.3 EJS44491.1 - 4.1e-06 25.2 4.2 0.13 10.3 0.0 4.2 1 1 3 4 4 4 4 Nucleoporin Nup120/160 DUF2408 PF10303.4 EJS44491.1 - 1.8 8.6 12.6 0.33 11.0 1.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Csm1 PF12539.3 EJS44492.1 - 1.9e-30 105.1 0.6 3e-30 104.5 0.1 1.6 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 ATG16 PF08614.6 EJS44492.1 - 9.7e-05 22.2 5.0 0.00018 21.4 3.4 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) BRE1 PF08647.6 EJS44492.1 - 0.00044 20.1 3.8 0.00044 20.1 2.7 1.7 2 0 0 2 2 1 1 BRE1 E3 ubiquitin ligase ADIP PF11559.3 EJS44492.1 - 0.0009 19.1 1.9 0.0009 19.1 1.3 1.6 2 0 0 2 2 1 1 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 EJS44492.1 - 0.0023 18.0 4.6 0.0023 18.0 3.2 1.9 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF3373 PF11853.3 EJS44492.1 - 0.0029 16.2 0.3 0.0029 16.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) Cep57_MT_bd PF06657.8 EJS44492.1 - 0.004 17.0 1.3 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Spc24 PF08286.6 EJS44492.1 - 0.0041 16.7 3.3 0.0041 16.7 2.3 1.8 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF4618 PF15397.1 EJS44492.1 - 0.0047 16.2 3.4 0.0047 16.2 2.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) Herpes_BLRF2 PF05812.7 EJS44492.1 - 0.0067 16.2 1.1 0.017 14.9 0.8 1.7 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein DUF3450 PF11932.3 EJS44492.1 - 0.0082 15.4 1.8 0.014 14.7 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4407 PF14362.1 EJS44492.1 - 0.0088 15.0 0.8 0.012 14.5 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.15 EJS44492.1 - 0.01 15.5 3.3 0.01 15.5 2.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit Reo_sigmaC PF04582.7 EJS44492.1 - 0.011 15.0 0.7 0.014 14.6 0.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Tmemb_cc2 PF10267.4 EJS44492.1 - 0.018 13.6 2.7 0.02 13.4 1.2 1.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Tnp_P_element PF12017.3 EJS44492.1 - 0.024 13.8 0.1 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Transposase protein Bap31 PF05529.7 EJS44492.1 - 0.026 13.9 3.0 0.047 13.1 2.0 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Phage_GP20 PF06810.6 EJS44492.1 - 0.029 13.8 8.0 0.086 12.2 5.5 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 FlaC_arch PF05377.6 EJS44492.1 - 0.031 14.1 3.5 0.082 12.8 2.4 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) RTBV_P46 PF06216.6 EJS44492.1 - 0.033 13.0 1.1 0.05 12.4 0.8 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Syntaxin-6_N PF09177.6 EJS44492.1 - 0.035 14.5 3.0 0.035 14.5 2.1 2.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.17 EJS44492.1 - 0.043 13.8 7.7 0.18 11.8 2.1 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3573 PF12097.3 EJS44492.1 - 0.051 12.1 1.6 0.074 11.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) V_ATPase_I PF01496.14 EJS44492.1 - 0.052 11.4 1.0 0.049 11.5 0.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cauli_AT PF03233.8 EJS44492.1 - 0.056 13.1 5.8 0.031 13.9 1.9 1.9 2 0 0 2 2 2 0 Aphid transmission protein DUF3161 PF11362.3 EJS44492.1 - 0.079 12.8 0.3 0.15 11.9 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3161) SlyX PF04102.7 EJS44492.1 - 0.12 12.7 2.3 0.27 11.6 1.6 1.7 1 0 0 1 1 1 0 SlyX DUF3138 PF11336.3 EJS44492.1 - 0.13 10.3 0.3 0.18 9.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) NPV_P10 PF05531.7 EJS44492.1 - 0.16 12.2 6.1 2.8 8.2 3.9 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF603 PF04645.7 EJS44492.1 - 0.19 11.6 6.0 0.25 11.2 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF603 COG2 PF06148.6 EJS44492.1 - 0.19 11.5 3.7 0.71 9.7 0.8 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.10 EJS44492.1 - 0.23 10.9 10.1 0.058 12.8 3.5 2.4 2 1 1 3 3 2 0 Septum formation initiator DUF2681 PF10883.3 EJS44492.1 - 0.28 11.3 3.5 0.78 9.9 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF724 PF05266.9 EJS44492.1 - 0.3 10.6 5.9 0.059 12.9 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4559 PF15112.1 EJS44492.1 - 0.32 10.1 7.3 0.14 11.3 3.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) GldM_N PF12081.3 EJS44492.1 - 0.41 10.1 7.3 0.08 12.4 2.3 1.7 2 0 0 2 2 2 0 GldM N-terminal domain Spc7 PF08317.6 EJS44492.1 - 0.42 9.2 8.7 0.032 12.9 2.1 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1759 PF03564.10 EJS44492.1 - 0.54 10.0 5.1 0.23 11.2 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF16 PF01519.11 EJS44492.1 - 0.55 10.4 6.8 0.22 11.7 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 FlxA PF14282.1 EJS44492.1 - 0.57 10.1 13.5 0.057 13.3 6.0 1.8 2 0 0 2 2 1 0 FlxA-like protein PFEMP PF03011.10 EJS44492.1 - 0.62 10.4 9.7 1.3 9.4 3.1 2.1 2 0 0 2 2 2 0 PFEMP DBL domain DUF4200 PF13863.1 EJS44492.1 - 0.95 9.4 10.0 0.041 13.8 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF948 PF06103.6 EJS44492.1 - 1.1 9.2 4.9 1.1 9.1 2.6 1.7 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EJS44492.1 - 3.6 7.1 9.1 0.19 11.3 2.2 1.8 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 EJS44492.1 - 4.5 7.6 8.4 0.46 10.8 1.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) FliJ PF02050.11 EJS44492.1 - 4.7 7.2 8.9 0.17 11.9 1.2 2.1 2 1 0 2 2 2 0 Flagellar FliJ protein bZIP_1 PF00170.16 EJS44492.1 - 5.4 7.0 9.9 0.31 11.0 1.2 2.6 2 1 1 3 3 2 0 bZIP transcription factor zf-LYAR PF08790.6 EJS44493.1 - 2.2e-15 56.0 7.3 4.8e-15 54.9 5.0 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-TRAF PF02176.13 EJS44493.1 - 0.09 13.1 2.3 0.15 12.4 1.6 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger DUF1180 PF06679.7 EJS44493.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) zf-GRF PF06839.7 EJS44493.1 - 0.39 10.6 4.1 1.1 9.1 2.9 1.9 1 0 0 1 1 1 0 GRF zinc finger zf-met PF12874.2 EJS44493.1 - 0.5 10.6 5.3 5 7.4 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EJS44493.1 - 0.57 10.3 5.0 1.1 9.4 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EJS44493.1 - 0.79 9.7 3.5 1.6 8.7 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EJS44493.1 - 1.2 9.5 6.4 0.65 10.4 0.7 2.5 1 1 1 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EJS44493.1 - 1.8 9.0 4.3 1.4e+02 3.1 2.9 2.5 1 1 0 1 1 1 0 C2H2-type zinc finger A2L_zn_ribbon PF08792.5 EJS44493.1 - 2 7.9 8.7 0.39 10.2 0.5 2.9 1 1 1 2 2 2 0 A2L zinc ribbon domain C1_4 PF07975.7 EJS44493.1 - 2.4 8.2 8.5 1 9.4 3.4 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain Tmemb_55A PF09788.4 EJS44493.1 - 8.5 5.4 10.5 4.6 6.3 3.1 2.1 1 1 1 2 2 2 0 Transmembrane protein 55A Cofilin_ADF PF00241.15 EJS44494.1 - 1.4e-24 86.3 0.0 3e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_9 PF14604.1 EJS44494.1 - 1.9e-14 52.9 0.4 4.3e-14 51.8 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EJS44494.1 - 2.3e-14 52.4 0.9 5.6e-14 51.2 0.7 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EJS44494.1 - 1.1e-06 28.0 0.0 2.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Flocculin_t3 PF13928.1 EJS44495.1 - 2.6e-12 46.6 100.8 7.5e-06 25.9 6.0 21.1 17 2 1 18 18 18 5 Flocculin type 3 repeat Peptidase_S8 PF00082.17 EJS44497.1 - 1.9e-44 151.9 0.0 2.5e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EJS44497.1 - 8.6e-07 29.4 0.0 1.7e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ribosomal_L19 PF01245.15 EJS44498.1 - 1e-11 44.6 0.1 1.4e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 WBS_methylT PF12589.3 EJS44499.1 - 1.2e-16 60.9 5.8 1.2e-16 60.9 4.0 1.7 2 0 0 2 2 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EJS44499.1 - 2.3e-12 47.2 0.0 4.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EJS44499.1 - 1.6e-06 27.8 0.0 3.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EJS44499.1 - 1.6e-06 28.5 0.0 8.9e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EJS44499.1 - 3.2e-06 27.4 0.0 7.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EJS44499.1 - 7.1e-06 25.8 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EJS44499.1 - 2.7e-05 23.3 0.2 0.00053 19.1 0.0 2.6 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EJS44499.1 - 5.5e-05 22.8 0.0 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EJS44499.1 - 9.7e-05 22.9 0.0 0.00047 20.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EJS44499.1 - 0.0015 18.5 0.0 0.0049 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EJS44499.1 - 0.0087 15.2 0.1 0.037 13.1 0.0 1.9 2 1 1 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EJS44499.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.8 EJS44499.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MRP-S33 PF08293.6 EJS44499.1 - 0.34 10.9 0.0 0.34 10.9 0.0 2.3 2 1 0 2 2 2 0 Mitochondrial ribosomal subunit S27 MBOAT PF03062.14 EJS44500.1 - 1.5e-73 247.7 41.5 1.9e-73 247.3 28.7 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Corona_nucleoca PF00937.13 EJS44500.1 - 0.012 14.5 10.5 0.019 13.9 7.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1509 PF07420.6 EJS44500.1 - 0.3 10.3 5.1 0.49 9.6 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Transformer PF06495.6 EJS44500.1 - 0.36 10.6 10.1 0.71 9.7 7.0 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein Apt1 PF10351.4 EJS44500.1 - 0.43 9.3 5.7 0.58 8.9 3.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.8 EJS44500.1 - 3.1 8.2 12.9 6.1 7.3 8.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain RAP1 PF07218.6 EJS44500.1 - 5.2 5.0 15.4 7.9 4.4 10.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ank_5 PF13857.1 EJS44501.1 - 1.8e-15 56.5 0.1 1.3e-11 44.3 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EJS44501.1 - 2.3e-10 40.6 0.5 1.9e-06 28.1 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EJS44501.1 - 1.3e-08 35.0 0.0 1.3e-07 31.8 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EJS44501.1 - 3.4e-07 29.7 0.1 0.00027 20.5 0.2 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EJS44501.1 - 7.8e-07 28.7 0.1 0.00084 19.3 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat SWIB PF02201.13 EJS44502.1 - 0.02 14.5 0.0 0.074 12.7 0.0 2.0 2 0 0 2 2 2 0 SWIB/MDM2 domain Prothymosin PF03247.9 EJS44502.1 - 3.8 7.7 20.6 2.8 8.1 5.2 2.8 2 0 0 2 2 2 0 Prothymosin/parathymosin family Thr_synth_N PF14821.1 EJS44503.1 - 4.4e-28 97.1 0.0 1.5e-27 95.3 0.0 2.0 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EJS44503.1 - 4.5e-18 65.5 0.0 7.2e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Atx10homo_assoc PF09759.4 EJS44504.1 - 2.9e-37 126.4 2.5 2.9e-37 126.4 0.3 2.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Cut8_M PF14483.1 EJS44504.1 - 0.11 12.3 0.1 0.35 10.6 0.1 1.9 1 0 0 1 1 1 0 Cut8 dimerisation domain WD40 PF00400.27 EJS44505.1 - 3e-62 204.4 17.5 7.2e-13 47.8 0.1 12.2 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 EJS44505.1 - 2.5e-25 88.5 0.0 4e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EJS44505.1 - 3.3e-09 36.7 9.5 0.00099 18.8 0.1 6.7 4 3 3 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EJS44505.1 - 9.5e-06 24.9 0.7 0.15 11.1 0.0 4.2 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EJS44505.1 - 1.2e-05 23.6 4.4 0.13 10.3 0.0 4.5 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EJS44505.1 - 0.00046 19.7 0.2 0.2 11.0 0.1 3.2 1 1 2 3 3 3 3 PQQ-like domain Apc4_WD40 PF12894.2 EJS44505.1 - 0.00064 19.1 0.0 13 5.3 0.0 4.6 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.11 EJS44505.1 - 0.00096 17.5 0.2 0.28 9.4 0.0 3.7 3 1 0 4 4 4 1 Cytochrome D1 heme domain PD40 PF07676.7 EJS44505.1 - 0.024 14.3 0.2 61 3.4 0.1 4.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.1 EJS44505.1 - 0.036 13.0 0.0 0.18 10.7 0.0 2.1 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Proteasome_A_N PF10584.4 EJS44505.1 - 0.58 9.5 3.9 1.8 7.9 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature UPF0029 PF01205.14 EJS44506.1 - 6.3e-30 103.0 0.1 9.3e-30 102.5 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EJS44506.1 - 2.1e-11 43.7 0.1 3.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain TPR_11 PF13414.1 EJS44507.1 - 4e-13 48.8 1.1 6.1e-13 48.2 0.6 1.4 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EJS44507.1 - 5.3e-11 41.6 0.6 9.5e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EJS44507.1 - 2.1e-10 40.9 3.8 8.6e-08 32.6 0.4 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EJS44507.1 - 4.1e-10 38.7 0.9 0.00044 19.9 0.3 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EJS44507.1 - 2.8e-09 37.1 1.3 4e-09 36.6 0.9 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EJS44507.1 - 4.8e-08 32.9 0.9 0.0014 19.0 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EJS44507.1 - 8.9e-06 25.1 0.1 0.1 12.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EJS44507.1 - 0.00013 21.4 0.1 0.035 13.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EJS44507.1 - 0.0003 20.5 0.1 0.038 13.8 0.0 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 EJS44507.1 - 0.00059 19.7 2.7 0.0016 18.3 0.8 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EJS44507.1 - 0.00069 19.6 1.3 0.0066 16.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EJS44507.1 - 0.00087 19.5 6.2 0.052 14.0 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EJS44507.1 - 0.00092 19.0 0.4 0.0017 18.2 0.3 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.9 EJS44507.1 - 0.0013 18.9 0.0 0.68 10.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EJS44507.1 - 0.0061 16.6 0.3 0.019 15.1 0.0 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EJS44507.1 - 0.064 13.2 2.8 3 7.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.2 EJS44507.1 - 0.12 12.2 0.1 0.61 9.9 0.1 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Ytp1 PF10355.4 EJS44508.1 - 1.5e-111 371.9 13.4 2.7e-111 371.1 9.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EJS44508.1 - 2.5e-28 97.7 4.2 2.5e-28 97.7 2.9 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) FixQ PF05545.6 EJS44508.1 - 0.5 10.0 0.0 0.5 10.0 0.0 3.1 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Myb_DNA-binding PF00249.26 EJS44509.1 - 1.7e-16 60.0 0.1 4e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EJS44509.1 - 1.5e-05 25.0 0.2 0.0083 16.2 0.1 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain ELO PF01151.13 EJS44510.1 - 2.1e-60 204.1 24.5 2.5e-60 203.8 17.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SPX PF03105.14 EJS44511.1 - 8.6e-47 160.2 15.6 5e-46 157.6 11.3 1.8 2 0 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 EJS44511.1 - 7.1e-19 68.0 31.1 1.1e-18 67.3 21.6 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EJS44511.1 - 1e-15 57.2 34.8 1.2e-15 57.0 11.8 2.1 1 1 1 2 2 2 1 Citrate transporter RFX_DNA_binding PF02257.10 EJS44511.1 - 0.051 13.7 0.3 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 RFX DNA-binding domain ATPase_gene1 PF09527.5 EJS44511.1 - 2.6 7.9 14.5 0.028 14.2 2.0 3.4 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) PfkB PF00294.19 EJS44512.1 - 2.4e-12 46.6 0.0 3.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 EJS44512.1 - 0.099 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase TENA_THI-4 PF03070.11 EJS44513.1 - 1.7e-15 57.3 1.7 2.4e-15 56.8 1.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family LSM PF01423.17 EJS44514.1 - 1.3e-11 43.8 0.0 1.6e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain GcpE PF04551.9 EJS44514.1 - 0.088 11.5 0.1 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 GcpE protein Bac_rhodopsin PF01036.13 EJS44515.1 - 3.6e-56 189.9 17.3 4.5e-56 189.6 12.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 EJS44515.1 - 0.0071 15.7 10.1 0.13 11.6 0.8 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) E1-E2_ATPase PF00122.15 EJS44515.1 - 2.5 7.0 4.0 2.7 6.9 0.1 2.3 2 1 0 2 2 2 0 E1-E2 ATPase tRNA-synt_2 PF00152.15 EJS44516.1 - 2.9e-72 243.2 0.0 4e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EJS44516.1 - 1.5e-08 34.4 0.0 2.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PMP1_2 PF08114.6 EJS44517.1 - 1.6e-30 104.3 4.6 1.7e-30 104.2 3.2 1.0 1 0 0 1 1 1 1 ATPase proteolipid family DUF1049 PF06305.6 EJS44517.1 - 0.0074 15.7 1.3 0.0095 15.3 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) Chordopox_A13L PF05961.6 EJS44517.1 - 0.17 11.8 0.4 0.18 11.7 0.3 1.1 1 0 0 1 1 1 0 Chordopoxvirus A13L protein P12 PF12669.2 EJS44517.1 - 0.7 10.1 2.6 0.73 10.0 1.8 1.1 1 0 0 1 1 1 0 Virus attachment protein p12 family Phosphodiest PF01663.17 EJS44518.1 - 2.7e-86 290.1 3.1 2.7e-86 290.1 2.2 1.4 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EJS44518.1 - 0.0016 17.7 0.0 0.0074 15.5 0.0 2.1 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.7 EJS44518.1 - 0.55 9.8 0.0 0.55 9.8 0.0 2.1 3 0 0 3 3 3 0 PglZ domain Ras PF00071.17 EJS44519.1 - 2.9e-45 153.5 0.0 3.4e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS44519.1 - 6.6e-12 45.9 0.0 1.1e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS44519.1 - 3.5e-07 29.6 0.0 4.4e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EJS44519.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EJS44519.1 - 2e-05 24.1 0.1 0.0019 17.6 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EJS44519.1 - 0.0017 17.6 0.0 0.002 17.3 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EJS44519.1 - 0.0021 17.9 0.0 0.0087 15.9 0.0 2.0 3 0 0 3 3 3 1 AAA domain FeoB_N PF02421.13 EJS44519.1 - 0.021 14.0 0.0 0.049 12.9 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 EJS44519.1 - 0.028 14.5 0.0 5 7.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EJS44519.1 - 0.1 12.3 0.3 0.2 11.3 0.2 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 EJS44519.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EJS44519.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GATA PF00320.22 EJS44520.1 - 3.1e-11 42.4 4.2 7e-11 41.2 2.9 1.7 1 0 0 1 1 1 1 GATA zinc finger ZZ PF00569.12 EJS44520.1 - 0.03 13.8 0.2 0.88 9.1 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, ZZ type Pkinase PF00069.20 EJS44521.1 - 1.5e-66 224.1 0.0 2.2e-66 223.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44521.1 - 6.6e-27 94.2 0.0 9.9e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS44521.1 - 0.0033 16.4 0.0 0.006 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EJS44521.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EJS44521.1 - 0.067 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EJS44521.1 - 0.12 11.7 0.5 0.5 9.6 0.0 2.2 3 0 0 3 3 3 0 RIO1 family BAR PF03114.13 EJS44522.1 - 2.3e-54 184.3 1.2 2.7e-54 184.1 0.8 1.0 1 0 0 1 1 1 1 BAR domain DUF1496 PF07383.7 EJS44522.1 - 0.00091 18.4 0.7 0.0017 17.5 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1496) Seryl_tRNA_N PF02403.17 EJS44522.1 - 0.03 14.3 3.4 1.5 8.9 0.7 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2130 PF09903.4 EJS44522.1 - 0.22 10.2 3.6 0.29 9.8 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF4164 PF13747.1 EJS44522.1 - 0.6 10.2 3.5 0.7 10.0 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Grp1_Fun34_YaaH PF01184.14 EJS44523.1 - 2.6e-95 317.6 17.6 3e-95 317.4 12.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 EJS44523.1 - 0.29 10.1 4.6 0.15 11.0 1.9 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) ABC2_membrane PF01061.19 EJS44524.1 - 2.1e-37 128.3 20.0 2.1e-37 128.3 13.9 2.2 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 EJS44524.1 - 6.4e-29 100.9 0.1 1.7e-28 99.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EJS44524.1 - 4.8e-05 22.6 0.2 0.00011 21.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EJS44524.1 - 0.001 19.0 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EJS44524.1 - 0.0028 17.0 0.1 0.048 13.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EJS44524.1 - 0.015 14.8 0.2 0.034 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain hEGF PF12661.2 EJS44524.1 - 0.015 15.3 3.0 0.015 15.3 2.1 3.5 3 0 0 3 3 2 0 Human growth factor-like EGF EGF_2 PF07974.8 EJS44524.1 - 0.019 15.0 28.3 0.019 15.0 4.1 4.2 4 0 0 4 4 3 0 EGF-like domain SbcCD_C PF13558.1 EJS44524.1 - 0.041 13.8 0.1 0.35 10.8 0.0 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EJS44524.1 - 0.041 14.0 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EJS44524.1 - 0.054 13.4 0.4 0.093 12.6 0.3 1.3 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.19 EJS44524.1 - 0.1 12.5 30.6 0.041 13.8 1.5 4.1 4 0 0 4 4 4 0 Laminin EGF-like (Domains III and V) PGK PF00162.14 EJS44525.1 - 9.6e-153 508.2 0.2 1.1e-152 508.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Mgr1 PF08602.5 EJS44526.1 - 9.2e-158 524.9 0.1 1e-157 524.8 0.1 1.0 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit Thioredoxin PF00085.15 EJS44527.1 - 1.1e-61 204.9 0.6 1.2e-30 105.2 0.3 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EJS44527.1 - 1.4e-26 93.4 3.8 1e-17 64.5 1.0 3.5 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EJS44527.1 - 3.4e-10 40.0 4.3 0.0012 19.0 0.2 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EJS44527.1 - 1.5e-09 37.7 0.1 0.00017 21.5 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EJS44527.1 - 1.3e-08 34.8 0.2 0.0063 16.6 0.0 3.6 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EJS44527.1 - 2.2e-07 30.5 0.2 0.0088 15.7 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 EJS44527.1 - 8.6e-05 22.1 0.2 0.1 12.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 EJS44527.1 - 0.00028 20.4 0.1 0.23 11.0 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.1 EJS44527.1 - 0.01 15.6 0.5 0.93 9.3 0.1 3.0 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin_4 PF13462.1 EJS44527.1 - 0.048 13.6 0.7 15 5.6 0.0 3.2 2 1 1 3 3 3 0 Thioredoxin TraF PF13728.1 EJS44527.1 - 0.071 12.5 0.0 0.66 9.4 0.0 2.4 2 0 0 2 2 2 0 F plasmid transfer operon protein Hexokinase_2 PF03727.11 EJS44528.1 - 4.3e-92 307.7 0.0 6.2e-92 307.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EJS44528.1 - 1.2e-77 259.8 0.0 2.7e-77 258.7 0.0 1.6 2 0 0 2 2 2 1 Hexokinase PqqD PF05402.7 EJS44528.1 - 0.02 14.8 0.3 0.051 13.5 0.2 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) WD40 PF00400.27 EJS44529.1 - 1e-10 41.0 9.1 0.003 17.3 0.2 5.9 6 1 0 6 6 6 3 WD domain, G-beta repeat DUF4221 PF13970.1 EJS44529.1 - 0.00011 21.6 0.2 0.0006 19.2 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4221) Lactonase PF10282.4 EJS44529.1 - 0.023 13.8 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller ATG22 PF11700.3 EJS44530.1 - 1.6e-160 534.7 29.3 1.8e-160 534.5 20.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EJS44530.1 - 1.8e-05 23.6 41.8 4.8e-05 22.2 5.0 3.6 1 1 2 3 3 3 2 Major Facilitator Superfamily La PF05383.12 EJS44531.1 - 1.1e-19 69.9 0.1 2.6e-19 68.7 0.0 1.6 2 0 0 2 2 2 1 La domain Glutaredoxin PF00462.19 EJS44532.1 - 9.6e-15 54.3 0.0 1.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 EJS44532.1 - 0.0022 17.5 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 EJS44532.1 - 0.0039 16.9 0.1 0.0076 16.0 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin domain DSBA PF01323.15 EJS44532.1 - 0.11 12.0 0.5 4.3 6.8 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EJS44532.1 - 0.13 12.2 0.6 2.7 8.0 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin GAT PF03127.9 EJS44533.1 - 1.2e-06 28.3 0.0 3.2e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 EJS44533.1 - 0.0018 17.8 0.1 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 VHS domain SelR PF01641.13 EJS44534.1 - 3.3e-50 168.9 0.1 4.1e-50 168.6 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 EJS44534.1 - 0.044 13.8 1.8 0.21 11.6 1.1 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 EJS44534.1 - 0.048 13.5 1.7 0.83 9.6 0.1 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EJS44534.1 - 0.22 11.3 3.3 1.8 8.4 2.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon Zn_ribbon_recom PF13408.1 EJS44534.1 - 0.41 10.9 2.9 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Mss51 PF13824.1 EJS44534.1 - 6.3 6.7 6.7 16 5.4 0.7 3.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Ste50p-SAM PF09235.5 EJS44535.1 - 1.3e-36 124.4 4.4 2.9e-36 123.3 3.1 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif RA PF00788.18 EJS44535.1 - 1.3e-15 57.6 0.0 3.4e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RRP7 PF12923.2 EJS44536.1 - 8.7e-34 116.3 6.5 1.3e-33 115.7 4.5 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) Histidinol_dh PF00815.15 EJS44537.1 - 2.2e-186 619.4 1.4 3.6e-186 618.7 1.0 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EJS44537.1 - 2.4e-28 97.5 0.1 4.4e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EJS44537.1 - 3.7e-11 43.1 0.2 1.6e-10 41.1 0.1 2.2 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase ACPS PF01648.15 EJS44537.1 - 0.0065 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily CAP_GLY PF01302.20 EJS44538.1 - 2.7e-15 55.8 0.1 4.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain zf-CCHC_4 PF14392.1 EJS44538.1 - 0.066 12.8 1.4 0.16 11.6 0.9 1.7 1 0 0 1 1 1 0 Zinc knuckle ACT_5 PF13710.1 EJS44538.1 - 0.15 11.9 5.8 5.3 6.9 0.1 3.7 4 0 0 4 4 4 0 ACT domain TMPIT PF07851.8 EJS44538.1 - 3.1 6.7 17.6 0.35 9.8 1.6 2.3 2 0 0 2 2 2 0 TMPIT-like protein Spc7 PF08317.6 EJS44538.1 - 8.1 5.0 27.6 7.1 5.1 6.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3452 PF11934.3 EJS44538.1 - 9.7 5.5 7.8 19 4.5 4.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) TPR_11 PF13414.1 EJS44539.1 - 0.0013 18.3 0.2 0.0069 16.0 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EJS44539.1 - 0.021 14.6 0.0 0.061 13.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SH3_1 PF00018.23 EJS44540.1 - 3.9e-06 26.1 0.1 2.1e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EJS44540.1 - 9.3e-06 25.1 0.0 2.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EJS44540.1 - 0.0026 17.2 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.5 EJS44540.1 - 0.013 14.8 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.1 EJS44540.1 - 0.022 14.2 3.3 0.16 11.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) DUF3611 PF12263.3 EJS44540.1 - 0.026 13.9 0.2 0.055 12.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3611) Mucin PF01456.12 EJS44540.1 - 0.028 14.2 11.2 0.048 13.4 7.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF485 PF04341.7 EJS44540.1 - 0.19 11.4 0.2 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Nitroreductase PF00881.19 EJS44541.1 - 1.3e-07 31.6 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family DUF1103 PF06513.6 EJS44541.1 - 0.14 11.5 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) Pkinase PF00069.20 EJS44542.1 - 7.3e-70 235.0 0.0 1.3e-69 234.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44542.1 - 1.2e-34 119.6 0.0 2e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS44542.1 - 4.5e-05 22.5 0.0 0.00013 21.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EJS44542.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Iso_dh PF00180.15 EJS44544.1 - 4.2e-132 440.3 0.0 4.8e-132 440.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_ligase_aden PF01653.13 EJS44544.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Aminotran_5 PF00266.14 EJS44545.1 - 8.6e-103 343.9 0.0 1.1e-102 343.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EJS44545.1 - 1.2e-08 34.2 0.0 2.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EJS44545.1 - 1.3e-08 34.4 0.0 1.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EJS44545.1 - 7.3e-07 28.5 0.1 1.8e-06 27.2 0.1 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EJS44545.1 - 0.001 17.5 0.0 0.0016 16.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EJS44545.1 - 0.0028 15.9 0.2 0.0046 15.2 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2036 PF09724.4 EJS44546.1 - 2e-89 299.9 0.1 2.3e-89 299.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF3507 PF12015.3 EJS44547.1 - 2e-63 213.2 0.1 6.1e-63 211.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3507) RRM_1 PF00076.17 EJS44548.1 - 5.4e-59 195.7 0.2 1.9e-19 69.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EJS44548.1 - 7e-36 122.0 0.1 3.3e-12 46.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS44548.1 - 3.8e-18 65.0 0.0 1.7e-09 37.3 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1325 PF07039.6 EJS44549.1 - 4.5e-35 120.0 0.0 1.1e-34 118.8 0.0 1.6 2 0 0 2 2 2 1 SGF29 tudor-like domain DUF4537 PF15057.1 EJS44549.1 - 0.039 13.7 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) DUF2856 PF11043.3 EJS44549.1 - 0.11 12.5 0.2 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) GHL5 PF14872.1 EJS44549.1 - 0.19 9.4 0.6 0.25 9.0 0.4 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 ALS_ss_C PF10369.4 EJS44550.1 - 1.8e-18 66.0 0.2 8.5e-18 63.8 0.0 2.2 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 EJS44550.1 - 1e-11 44.0 0.1 1.8e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EJS44550.1 - 6.6e-09 35.4 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain Limkain-b1 PF11608.3 EJS44550.1 - 0.0088 15.7 0.2 0.096 12.4 0.0 2.6 3 0 0 3 3 3 1 Limkain b1 ACT_4 PF13291.1 EJS44550.1 - 0.093 13.0 0.1 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 ACT domain UEV PF05743.8 EJS44551.1 - 3.3e-28 97.7 0.1 6.9e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EJS44551.1 - 1.9e-25 88.2 0.6 4.8e-25 86.9 0.0 1.9 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.21 EJS44551.1 - 0.00034 20.0 1.3 0.00078 18.8 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2764 PF10962.3 EJS44551.1 - 0.088 12.0 0.6 0.12 11.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) Rer1 PF03248.8 EJS44553.1 - 2.4e-76 255.2 4.6 2.8e-76 255.0 3.2 1.0 1 0 0 1 1 1 1 Rer1 family Septin PF00735.13 EJS44554.1 - 2.9e-107 357.9 1.1 3.4e-107 357.6 0.8 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EJS44554.1 - 1.6e-08 34.4 0.0 3.1e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EJS44554.1 - 6.5e-08 31.9 0.0 1.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EJS44554.1 - 7.3e-07 28.5 0.2 2.2e-06 26.9 0.2 1.8 1 1 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EJS44554.1 - 1.1e-06 28.2 0.4 3.1e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EJS44554.1 - 0.00011 22.0 1.1 0.072 12.9 0.2 2.5 1 1 1 2 2 2 2 Dynamin family AAA_24 PF13479.1 EJS44554.1 - 0.00021 20.9 0.1 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EJS44554.1 - 0.00025 20.6 0.0 0.00032 20.2 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EJS44554.1 - 0.00043 19.8 0.1 0.0013 18.1 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 EJS44554.1 - 0.0022 17.2 0.4 0.019 14.1 0.3 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.17 EJS44554.1 - 0.003 16.4 0.0 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Miro PF08477.8 EJS44554.1 - 0.0033 17.8 0.1 0.0081 16.6 0.1 1.9 1 1 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EJS44554.1 - 0.0037 17.2 0.1 0.0085 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EJS44554.1 - 0.0045 17.1 0.1 0.0099 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EJS44554.1 - 0.0051 17.1 1.1 0.014 15.6 0.4 2.0 2 1 0 2 2 2 1 ABC transporter AAA_14 PF13173.1 EJS44554.1 - 0.0067 16.3 0.1 0.036 13.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain IIGP PF05049.8 EJS44554.1 - 0.007 15.2 0.3 0.013 14.2 0.1 1.6 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_23 PF13476.1 EJS44554.1 - 0.0082 16.4 0.4 0.015 15.6 0.2 1.4 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EJS44554.1 - 0.011 15.0 0.1 0.92 8.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EJS44554.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EJS44554.1 - 0.021 14.5 0.3 0.16 11.6 0.1 2.5 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_32 PF13654.1 EJS44554.1 - 0.031 12.9 0.1 0.093 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EJS44554.1 - 0.033 13.6 0.2 0.75 9.2 0.1 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 EJS44554.1 - 0.037 12.9 0.1 0.067 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EJS44554.1 - 0.046 13.5 0.1 0.12 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EJS44554.1 - 0.081 13.7 0.5 0.25 12.1 0.3 2.1 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 EJS44554.1 - 0.095 11.4 0.0 0.43 9.3 0.0 1.9 2 0 0 2 2 2 0 ArgK protein Ribosomal_L32p PF01783.18 EJS44555.1 - 6e-10 39.1 5.5 9.6e-10 38.5 3.8 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family CpXC PF14353.1 EJS44555.1 - 0.018 15.0 0.7 0.025 14.5 0.5 1.3 1 0 0 1 1 1 0 CpXC protein Flavodoxin_1 PF00258.20 EJS44556.1 - 3.8e-09 36.6 0.0 6.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EJS44556.1 - 6.9e-08 32.1 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EJS44556.1 - 5.7e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold Citrate_synt PF00285.16 EJS44557.1 - 5.3e-103 344.4 0.0 6.7e-103 344.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase MAT_Alpha1 PF04769.7 EJS44558.1 - 1.6e-30 105.9 1.2 1.8e-30 105.8 0.9 1.0 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 PALP PF00291.20 EJS44559.1 - 1.5e-66 224.7 0.0 1.7e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_4 PF13407.1 EJS44559.1 - 0.08 12.2 0.1 0.34 10.2 0.0 1.9 2 1 0 2 2 2 0 Periplasmic binding protein domain KH_1 PF00013.24 EJS44561.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 KH domain KH_3 PF13014.1 EJS44561.1 - 0.051 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 KH domain Spore_GerAC PF05504.6 EJS44561.1 - 6.1 6.5 11.5 40 3.9 0.0 3.1 2 1 1 3 3 3 0 Spore germination B3/ GerAC like, C-terminal Med8 PF10232.4 EJS44562.1 - 0.042 13.3 3.1 0.038 13.5 1.6 1.3 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Peptidase_M3 PF01432.15 EJS44563.1 - 1.9e-157 525.0 0.2 2.5e-157 524.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EJS44563.1 - 0.025 14.6 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Effector protein MT-A70 PF05063.9 EJS44565.1 - 6.5e-14 51.8 0.0 1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 MT-A70 EZH2_WD-Binding PF11616.3 EJS44565.1 - 0.051 13.4 1.5 0.1 12.4 1.1 1.5 1 0 0 1 1 1 0 WD repeat binding protein EZH2 PIG-X PF08320.7 EJS44566.1 - 6e-51 172.6 0.0 8.1e-51 172.2 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 ATP_transf PF09830.4 EJS44568.1 - 5.3e-21 74.1 0.0 1.5e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 ATP adenylyltransferase HIT PF01230.18 EJS44568.1 - 0.0022 18.4 0.0 0.0046 17.4 0.0 1.5 1 0 0 1 1 1 1 HIT domain DUF1180 PF06679.7 EJS44569.1 - 0.43 10.4 2.2 0.43 10.4 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CbtB PF09489.5 EJS44569.1 - 6.6 6.7 6.0 1.1 9.2 1.6 1.6 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Recep_L_domain PF01030.19 EJS44570.1 - 4.2e-09 36.3 15.2 0.00041 20.2 0.1 4.7 1 1 1 3 3 3 2 Receptor L domain LRR_5 PF13306.1 EJS44570.1 - 0.017 14.8 0.6 0.017 14.8 0.4 2.9 1 1 2 3 3 3 0 Leucine rich repeats (6 copies) PGG PF13962.1 EJS44570.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function CTP_transf_2 PF01467.21 EJS44571.1 - 2.5e-05 24.4 0.1 0.00026 21.0 0.1 2.2 1 1 0 1 1 1 1 Cytidylyltransferase DUF1620 PF07774.8 EJS44572.1 - 3.8e-73 245.3 0.2 6e-73 244.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EJS44572.1 - 0.00016 21.2 0.0 0.022 14.2 0.0 2.6 2 1 0 2 2 2 2 PQQ-like domain Rrn6 PF10214.4 EJS44573.1 - 6.7e-160 533.7 33.1 7.8e-160 533.5 22.9 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF3361 PF11841.3 EJS44574.1 - 0.019 14.6 0.6 1.7 8.3 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) DUF3635 PF12330.3 EJS44575.1 - 2.3e-29 101.3 1.8 3.8e-29 100.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) WD40 PF00400.27 EJS44576.1 - 7.6e-43 142.9 17.3 1.7e-10 40.3 0.1 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat HIRA_B PF09453.5 EJS44576.1 - 3e-08 32.9 0.3 8.8e-08 31.5 0.2 1.8 1 0 0 1 1 1 1 HIRA B motif Hira PF07569.6 EJS44576.1 - 8.3e-06 25.1 0.0 1.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split PD40 PF07676.7 EJS44576.1 - 2.1e-05 24.0 0.2 1.4 8.6 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EJS44576.1 - 0.008 15.3 0.0 0.11 11.6 0.0 2.5 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EJS44576.1 - 0.028 12.2 0.0 1.6 6.4 0.0 2.5 2 0 0 2 2 2 0 IKI3 family Histone PF00125.19 EJS44577.1 - 6.7e-26 90.2 0.0 8.8e-26 89.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EJS44577.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EJS44578.1 - 1.1e-21 76.6 0.3 1.6e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EJS44578.1 - 6.7e-06 26.0 0.1 1.4e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EJS44578.1 - 0.0013 18.9 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 EJS44578.1 - 0.021 13.4 2.5 0.027 13.1 1.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1018 PF06252.7 EJS44578.1 - 0.11 12.9 0.3 0.15 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) CENP-W PF15510.1 EJS44578.1 - 0.15 12.0 0.6 2.4 8.1 0.4 2.1 1 1 0 1 1 1 0 Centromere kinetochore component W RNA_pol_Rpb2_1 PF04563.10 EJS44578.1 - 1.1 8.0 4.3 5.1 5.9 0.8 2.0 1 1 1 2 2 2 0 RNA polymerase beta subunit DUF77 PF01910.12 EJS44579.1 - 6.3e-30 102.6 0.1 7.1e-30 102.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Prenyltransf PF01255.14 EJS44580.1 - 8e-78 260.6 0.0 1e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase polyprenyl_synt PF00348.12 EJS44581.1 - 6.9e-53 179.1 0.0 2.3e-24 85.6 0.0 3.1 3 0 0 3 3 3 3 Polyprenyl synthetase DUF2990 PF11693.3 EJS44581.1 - 0.044 13.6 0.0 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) Mannosyl_trans2 PF04188.8 EJS44582.1 - 5.3e-142 473.8 40.8 4e-141 470.9 28.3 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) Aldedh PF00171.17 EJS44583.1 - 6.8e-156 519.2 0.0 7.6e-156 519.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EJS44583.1 - 0.038 13.2 0.1 0.083 12.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Histone PF00125.19 EJS44584.1 - 7.9e-15 54.7 0.2 9.6e-15 54.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EJS44584.1 - 7e-05 22.9 0.1 9.7e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EJS44584.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EJS44584.1 - 0.00018 21.4 0.1 0.00032 20.6 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EJS44584.1 - 0.0021 17.3 0.0 0.0022 17.2 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EJS44584.1 - 0.024 14.3 0.0 0.029 14.0 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EJS44584.1 - 0.06 13.6 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 EJS44585.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EJS44585.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EJS44585.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EJS44585.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Pyrophosphatase PF00719.14 EJS44586.1 - 3e-53 179.4 0.2 3.9e-53 179.0 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Glutaredoxin PF00462.19 EJS44587.1 - 3e-14 52.7 0.0 6.4e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin SpoIISA_toxin PF14171.1 EJS44587.1 - 0.013 14.7 0.1 0.013 14.7 0.1 1.5 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system Thioredoxin_7 PF13899.1 EJS44587.1 - 0.032 14.2 0.0 0.078 13.0 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like MacB_PCD PF12704.2 EJS44587.1 - 0.063 12.8 0.1 0.19 11.3 0.0 1.7 1 1 0 2 2 2 0 MacB-like periplasmic core domain Thioredoxin_9 PF14595.1 EJS44587.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Mannosyl_trans3 PF11051.3 EJS44588.1 - 3.7e-86 288.8 0.0 6.4e-86 288.0 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative DUF3724 PF12521.3 EJS44588.1 - 0.052 13.2 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) CYSTM PF12734.2 EJS44589.1 - 2.1e-05 24.5 61.2 2.5e+02 1.8 42.4 5.2 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 EJS44589.1 - 0.21 11.6 33.9 0.39 10.8 23.5 1.4 1 0 0 1 1 1 0 Proline-rich HEAT PF02985.17 EJS44590.1 - 1.8e-21 74.2 8.1 0.0037 17.2 0.0 9.8 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 EJS44590.1 - 3.1e-21 75.2 0.3 7.7e-11 42.1 0.0 8.3 8 0 0 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.1 EJS44590.1 - 2.7e-16 59.5 0.0 5.8e-06 26.5 0.0 6.7 4 3 4 8 8 8 7 HEAT repeats Cnd1 PF12717.2 EJS44590.1 - 1.1e-05 25.3 7.3 0.015 15.1 0.0 4.5 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EJS44590.1 - 7.4e-05 23.0 0.0 0.96 9.8 0.0 4.4 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EJS44590.1 - 0.019 14.8 0.0 0.11 12.4 0.0 2.4 1 1 0 1 1 1 0 Importin-beta N-terminal domain Arm PF00514.18 EJS44590.1 - 0.65 9.9 2.9 56 3.7 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat GalP_UDP_transf PF01087.17 EJS44591.1 - 3.6e-66 222.6 0.2 4.9e-66 222.2 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EJS44591.1 - 4.4e-64 215.0 0.7 7.7e-64 214.2 0.1 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain WG_beta_rep PF14903.1 EJS44591.1 - 0.065 13.5 0.1 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 WG containing repeat DUF3288 PF11691.3 EJS44591.1 - 0.12 12.1 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) Aldose_epim PF01263.15 EJS44592.1 - 1.4e-83 280.4 0.6 1.9e-83 280.0 0.4 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 EJS44592.1 - 3.3e-53 180.5 0.0 6.7e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EJS44592.1 - 1.3e-21 76.2 0.1 2.8e-21 75.2 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EJS44592.1 - 1.2e-18 67.0 0.0 8.6e-17 60.9 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EJS44592.1 - 3.1e-16 58.9 0.0 1e-15 57.1 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EJS44592.1 - 2.6e-11 42.9 0.0 3.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EJS44592.1 - 5.2e-11 42.7 0.0 8.3e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EJS44592.1 - 2.6e-08 33.1 0.0 5.1e-07 28.8 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EJS44592.1 - 8e-08 32.1 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EJS44592.1 - 1.4e-06 28.4 0.0 2.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding GalKase_gal_bdg PF10509.4 EJS44593.1 - 1.3e-22 78.7 0.0 3.3e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EJS44593.1 - 1.9e-15 56.6 0.2 5.3e-15 55.2 0.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EJS44593.1 - 2.3e-11 43.7 0.0 5.5e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M16_C PF05193.16 EJS44593.1 - 0.086 12.5 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Peptidase M16 inactive domain Transp_cyt_pur PF02133.10 EJS44594.1 - 4.7e-182 605.4 36.6 5.4e-182 605.2 25.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Macro PF01661.16 EJS44595.1 - 1.2e-28 99.3 0.0 1.5e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Macro domain Chitin_synth_2 PF03142.10 EJS44596.1 - 8.7e-289 958.2 1.0 1.2e-288 957.7 0.1 1.6 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EJS44596.1 - 3e-15 56.4 2.2 1.1e-14 54.5 1.5 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EJS44596.1 - 1.9e-13 50.7 0.0 1.3e-10 41.4 0.0 2.5 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EJS44596.1 - 1.1e-06 28.2 0.3 0.0029 17.3 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EJS44596.1 - 0.00051 19.3 0.1 0.0019 17.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EJS44596.1 - 0.013 15.1 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 SCO1-SenC PF02630.9 EJS44597.1 - 2.1e-74 248.8 0.0 2.8e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EJS44597.1 - 1.2e-06 28.2 0.0 2.5e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EJS44597.1 - 0.00044 20.3 0.1 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like YchF-GTPase_C PF06071.8 EJS44598.1 - 2.5e-36 123.3 0.3 8.7e-36 121.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EJS44598.1 - 2.8e-13 49.8 0.0 1.8e-12 47.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EJS44598.1 - 0.0041 16.4 0.0 0.009 15.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EJS44598.1 - 0.0068 16.2 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 TGS domain SecA_PP_bind PF01043.15 EJS44598.1 - 0.03 14.6 0.4 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 SecA preprotein cross-linking domain AAA_23 PF13476.1 EJS44598.1 - 0.09 13.0 0.6 0.28 11.4 0.4 1.9 1 1 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.21 EJS44599.1 - 2.8e-07 30.1 0.0 5.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CwfJ_C_2 PF04676.9 EJS44599.1 - 0.022 15.2 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 DUF1027 PF06265.6 EJS44599.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Pkinase PF00069.20 EJS44600.1 - 1.1e-64 218.1 0.0 2.1e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44600.1 - 3.7e-33 114.7 0.0 5.8e-32 110.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EJS44600.1 - 0.00012 22.5 0.7 0.00039 20.8 0.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EJS44600.1 - 0.0051 15.8 0.0 0.022 13.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like TPR_3 PF07720.7 EJS44600.1 - 0.66 9.8 4.3 7.5 6.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CTP_transf_1 PF01148.15 EJS44601.1 - 8.6e-82 274.6 21.8 1.1e-81 274.3 15.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family SET PF00856.23 EJS44602.1 - 2.7e-08 34.3 0.1 4.3e-06 27.1 0.0 3.3 2 1 0 2 2 2 1 SET domain CENP-B_dimeris PF09026.5 EJS44602.1 - 0.035 14.3 0.0 0.035 14.3 0.0 3.2 2 1 0 2 2 2 0 Centromere protein B dimerisation domain CDC45 PF02724.9 EJS44602.1 - 0.3 9.0 3.3 0.55 8.2 2.3 1.4 1 0 0 1 1 1 0 CDC45-like protein ATP-synt_ab PF00006.20 EJS44603.1 - 2.1e-70 236.5 0.0 3.3e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EJS44603.1 - 9.3e-27 93.7 0.2 2.6e-26 92.3 0.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EJS44603.1 - 1e-16 60.8 1.5 2.7e-16 59.5 1.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Tex_N PF09371.5 EJS44603.1 - 0.0048 16.2 0.4 0.41 9.9 0.0 2.3 2 0 0 2 2 2 1 Tex-like protein N-terminal domain HAS-barrel PF09378.5 EJS44603.1 - 0.012 15.5 0.3 0.045 13.6 0.2 2.1 1 1 0 1 1 1 0 HAS barrel domain AAA_25 PF13481.1 EJS44603.1 - 0.031 13.6 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.14 EJS44604.1 - 4.2e-19 68.8 0.0 1.4e-18 67.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EJS44604.1 - 2.1e-06 28.0 0.0 8.6e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EJS44604.1 - 3.2e-06 26.3 0.0 3.1e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EJS44604.1 - 1.2e-05 24.3 0.0 1.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EJS44604.1 - 1.8e-05 24.6 0.0 4.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EJS44604.1 - 3.2e-05 23.6 0.0 5.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 EJS44604.1 - 7.8e-05 21.6 0.0 0.00098 18.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase ApbA PF02558.11 EJS44604.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EJS44604.1 - 0.0024 17.2 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 EJS44604.1 - 0.0038 17.1 0.1 0.016 15.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EJS44604.1 - 0.026 14.2 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 EJS44604.1 - 0.047 12.1 0.0 0.13 10.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EJS44604.1 - 0.055 12.2 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.10 EJS44604.1 - 0.086 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 4HBT PF03061.17 EJS44605.1 - 7e-05 22.8 0.0 0.00015 21.7 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily Rox3 PF08633.5 EJS44606.1 - 2.4e-67 227.0 0.8 2.7e-67 226.8 0.6 1.0 1 0 0 1 1 1 1 Rox3 mediator complex subunit Ribosomal_L32e PF01655.13 EJS44607.1 - 1.7e-46 156.7 2.3 2e-46 156.5 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF3437 PF11919.3 EJS44607.1 - 0.091 12.4 0.4 0.19 11.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Peptidase_M24 PF00557.19 EJS44608.1 - 4.1e-55 186.5 0.1 5.3e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF612 PF04747.7 EJS44608.1 - 0.0044 15.9 3.5 0.006 15.5 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF612 MiaE_2 PF13794.1 EJS44608.1 - 0.14 11.6 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Ribosomal_S21 PF01165.15 EJS44609.1 - 2.5e-12 46.0 1.2 6e-12 44.8 0.8 1.7 1 0 0 1 1 1 1 Ribosomal protein S21 Aa_trans PF01490.13 EJS44610.1 - 2.4e-122 408.3 15.5 2.7e-122 408.1 10.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EJS44610.1 - 1.4e-06 27.4 6.8 1.4e-06 27.4 4.7 2.0 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family SPC25 PF06703.6 EJS44610.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4228 PF14009.1 EJS44610.1 - 0.21 11.7 0.0 0.35 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) NT-C2 PF10358.4 EJS44611.1 - 6.3e-47 158.6 0.9 1.8e-46 157.1 0.9 1.5 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins PH PF00169.24 EJS44612.1 - 4.9e-14 52.3 0.0 4.9e-14 52.3 0.0 2.8 3 1 0 3 3 3 1 PH domain SH3_1 PF00018.23 EJS44612.1 - 5.9e-13 47.9 0.2 1.1e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 EJS44612.1 - 1.5e-11 43.9 0.0 4e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EJS44612.1 - 1.1e-08 34.5 0.1 2e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 EJS44612.1 - 1.5e-08 34.8 3.5 5e-08 33.1 0.0 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EJS44612.1 - 8.2e-06 25.8 0.0 0.00038 20.4 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.12 EJS44612.1 - 0.0014 18.0 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EJS44612.1 - 0.048 13.8 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF3953 PF13129.1 EJS44612.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) TPR_2 PF07719.12 EJS44613.1 - 1.3e-39 130.8 7.8 9.1e-07 28.3 0.1 8.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.1 EJS44613.1 - 2.3e-33 113.6 18.7 1.3e-12 47.1 1.1 7.7 4 2 5 9 9 9 6 TPR repeat TPR_1 PF00515.23 EJS44613.1 - 1.4e-32 109.9 12.5 5.6e-09 35.2 0.0 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat Apc3 PF12895.2 EJS44613.1 - 3e-29 100.9 25.0 1.1e-16 60.7 3.4 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EJS44613.1 - 8e-26 87.8 6.2 9.8e-05 21.8 0.1 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 EJS44613.1 - 1.5e-22 79.2 10.4 3.7e-06 26.7 0.5 7.6 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EJS44613.1 - 4.5e-21 74.9 0.5 7.6e-08 32.8 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EJS44613.1 - 1.3e-19 68.6 10.3 6e-06 26.0 0.2 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 EJS44613.1 - 2e-13 49.7 7.5 0.027 14.9 0.0 7.4 9 0 0 9 9 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EJS44613.1 - 3.6e-13 49.6 3.0 0.00049 20.3 0.1 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EJS44613.1 - 6.5e-13 48.0 0.1 0.027 15.0 0.0 6.6 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EJS44613.1 - 8e-10 38.4 0.1 4e-05 23.3 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EJS44613.1 - 1.2e-09 37.2 5.2 1.6 8.7 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 EJS44613.1 - 0.00015 20.9 0.0 0.026 13.5 0.0 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 EJS44613.1 - 0.00048 20.1 0.0 0.17 12.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EJS44613.1 - 0.0071 16.2 1.9 0.67 9.9 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat Sel1 PF08238.7 EJS44613.1 - 0.2 12.3 4.7 30 5.4 0.0 4.6 5 0 0 5 5 4 0 Sel1 repeat Fis1_TPR_C PF14853.1 EJS44613.1 - 0.73 9.7 6.3 4.7 7.1 0.1 4.6 5 1 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Menin PF05053.8 EJS44614.1 - 1.6 6.7 10.9 2.1 6.3 7.5 1.2 1 0 0 1 1 1 0 Menin GatB_N PF02934.10 EJS44615.1 - 5.5e-93 310.9 0.0 7.3e-93 310.5 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EJS44615.1 - 2.7e-30 105.0 0.0 4.3e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 GatB domain Nucleoporin_C PF03177.9 EJS44616.1 - 1.2e-128 430.2 17.5 1.7e-128 429.7 12.2 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EJS44616.1 - 1.1e-111 373.6 11.3 2.5e-111 372.4 7.9 1.7 1 0 0 1 1 1 1 Nup133 N terminal like Atg8 PF02991.11 EJS44617.1 - 8.6e-51 170.2 0.1 9.8e-51 170.0 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EJS44617.1 - 7.3e-07 29.3 0.0 9.2e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA-synt_1 PF00133.17 EJS44618.1 - 5.1e-242 804.1 0.3 4.1e-241 801.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EJS44618.1 - 3.4e-27 95.1 0.0 1e-26 93.5 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EJS44618.1 - 2.7e-19 69.1 3.1 1.2e-06 27.4 0.4 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EJS44618.1 - 0.0003 20.0 0.0 0.00093 18.3 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain HSP70 PF00012.15 EJS44619.1 - 1.1e-269 895.5 7.2 1.2e-269 895.3 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EJS44619.1 - 1.4e-16 59.9 0.1 1.7e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EJS44619.1 - 0.00032 20.3 0.0 0.00061 19.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EJS44619.1 - 0.017 13.9 0.5 0.34 9.7 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain PEARLI-4 PF05278.7 EJS44619.1 - 0.029 13.7 2.4 0.042 13.2 0.0 2.0 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Ribosomal_S8e PF01201.17 EJS44620.1 - 6.6e-51 171.9 2.4 7.5e-51 171.7 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e zf-CSL PF05207.8 EJS44621.1 - 7.7e-24 82.9 1.4 1e-23 82.6 1.0 1.2 1 0 0 1 1 1 1 CSL zinc finger TF_Zn_Ribbon PF08271.7 EJS44621.1 - 0.024 13.9 1.3 0.047 13.0 0.9 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RING_4 PF14570.1 EJS44621.1 - 0.36 10.4 2.4 0.64 9.6 1.7 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain ADH_zinc_N_2 PF13602.1 EJS44622.1 - 6.1e-13 49.7 0.0 1.2e-12 48.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EJS44622.1 - 6.7e-07 29.0 0.1 1.3e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EJS44622.1 - 0.02 14.4 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase SplA PF11132.3 EJS44622.1 - 0.16 11.7 0.6 0.47 10.2 0.1 2.0 3 0 0 3 3 3 0 Transcriptional regulator protein (SplA) Pribosyltran_N PF13793.1 EJS44623.1 - 2.3e-42 143.3 0.1 2.6e-40 136.7 0.0 2.2 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EJS44623.1 - 5.3e-33 114.3 1.8 1.7e-27 96.3 0.2 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EJS44623.1 - 1.3e-12 47.5 1.1 3.9e-12 45.9 0.5 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EJS44623.1 - 0.00051 19.3 0.0 0.00084 18.6 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UCH PF00443.24 EJS44624.1 - 3.2e-77 259.2 0.9 6.8e-77 258.2 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EJS44624.1 - 1.4e-28 100.1 3.9 3.2e-23 82.5 0.4 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Fungal_trans PF04082.13 EJS44625.1 - 2e-28 99.0 2.8 5.3e-28 97.5 2.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EJS44625.1 - 4e-11 42.6 10.4 6.7e-11 41.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.16 EJS44626.1 - 8.5e-33 112.6 0.1 1.4e-32 112.0 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EJS44626.1 - 4.1e-15 55.1 0.1 7.2e-15 54.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EJS44626.1 - 1.8e-10 40.5 0.0 2.6e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin Kinesin PF00225.18 EJS44627.1 - 2.8e-109 364.8 9.7 2.8e-109 364.8 6.7 2.6 3 0 0 3 3 3 1 Kinesin motor domain Apolipoprotein PF01442.13 EJS44627.1 - 0.0029 17.1 10.1 0.1 12.0 0.5 3.5 2 1 2 4 4 4 3 Apolipoprotein A1/A4/E domain Sel1 PF08238.7 EJS44628.1 - 3.3e-43 145.1 15.7 1.2e-10 41.6 0.4 7.5 7 0 0 7 7 7 7 Sel1 repeat SEP PF08059.8 EJS44629.1 - 2.3e-26 91.8 0.1 5.8e-26 90.6 0.1 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EJS44629.1 - 1.4e-17 63.5 0.1 2.9e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EJS44629.1 - 1.2e-09 37.5 1.1 2.3e-09 36.6 0.8 1.5 1 0 0 1 1 1 1 UBA-like domain PP2C PF00481.16 EJS44630.1 - 4.3e-85 285.1 0.1 6.7e-85 284.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-bind_6 PF13921.1 EJS44631.1 - 1.4e-12 47.5 4.4 6.5e-10 38.9 0.2 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EJS44631.1 - 1.2e-07 31.6 1.3 6.6e-07 29.2 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.3 EJS44631.1 - 0.074 12.9 0.2 0.84 9.5 0.1 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain RRM_6 PF14259.1 EJS44632.1 - 4.4e-09 36.2 0.0 8.6e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EJS44632.1 - 8.4e-07 28.5 0.0 2.3e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EJS44632.1 - 0.00025 20.8 0.0 0.00057 19.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 EJS44632.1 - 0.019 14.9 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 Yippee-Mis18 PF03226.9 EJS44633.1 - 7.4e-19 67.5 3.9 9.4e-19 67.2 2.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Evr1_Alr PF04777.8 EJS44633.1 - 0.072 12.9 0.7 0.21 11.5 0.0 1.9 1 1 1 2 2 2 0 Erv1 / Alr family PLATZ PF04640.9 EJS44633.1 - 0.69 10.1 3.4 2.1 8.6 0.2 2.5 2 1 1 3 3 3 0 PLATZ transcription factor TP2 PF01254.13 EJS44633.1 - 1.3 9.3 6.1 1.7 9.0 2.3 2.1 1 1 1 2 2 2 0 Nuclear transition protein 2 EF-hand_4 PF12763.2 EJS44634.1 - 2e-32 111.0 0.0 5.8e-09 35.6 0.0 4.2 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EJS44634.1 - 4.1e-09 36.4 0.0 0.018 15.1 0.0 4.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EJS44634.1 - 6.1e-09 34.5 0.2 0.0018 17.4 0.0 3.7 3 0 0 3 3 3 2 EF hand UBA PF00627.26 EJS44634.1 - 6.6e-09 35.3 0.1 2.1e-08 33.7 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 EJS44634.1 - 3.6e-06 26.3 0.0 0.49 10.4 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain UBA_4 PF14555.1 EJS44634.1 - 3.8e-05 23.1 0.6 0.00014 21.3 0.4 1.9 1 0 0 1 1 1 1 UBA-like domain IncA PF04156.9 EJS44634.1 - 0.00026 20.6 54.8 0.11 12.0 16.5 3.9 1 1 2 3 3 3 2 IncA protein CENP-F_leu_zip PF10473.4 EJS44634.1 - 0.0021 17.8 30.6 0.0021 17.8 21.2 3.2 3 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_8 PF13833.1 EJS44634.1 - 0.0058 16.2 0.2 5.4 6.7 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain pair TPR_MLP1_2 PF07926.7 EJS44634.1 - 2 8.1 66.5 0.012 15.3 17.2 4.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 EJS44634.1 - 7.7 6.4 61.2 0.22 11.5 9.4 4.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) DUF3584 PF12128.3 EJS44634.1 - 8.3 3.5 76.1 0.0014 16.1 39.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) PPP4R2 PF09184.6 EJS44635.1 - 7e-70 235.8 16.3 7e-70 235.8 11.3 1.9 2 0 0 2 2 2 1 PPP4R2 Peptidase_M16 PF00675.15 EJS44636.1 - 2.9e-31 108.2 0.3 1.3e-30 106.1 0.1 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EJS44636.1 - 1e-26 93.7 0.2 3.1e-26 92.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Proteasome PF00227.21 EJS44638.1 - 3e-35 121.2 0.1 2.1e-34 118.4 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit DUF2121 PF09894.4 EJS44638.1 - 0.1 11.8 0.1 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) CTP_synth_N PF06418.9 EJS44640.1 - 1.4e-119 398.2 0.6 1.9e-119 397.8 0.4 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EJS44640.1 - 6.6e-57 192.0 0.0 9.8e-57 191.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EJS44640.1 - 8.3e-05 22.1 0.0 0.00039 19.9 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EJS44640.1 - 0.02 14.2 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_L16 PF00252.13 EJS44641.1 - 2e-34 118.2 0.1 2.9e-34 117.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Adaptin_N PF01602.15 EJS44642.1 - 1.2e-132 442.9 21.5 1.4e-132 442.7 14.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EJS44642.1 - 1.7e-07 31.5 1.5 2.6e-07 30.9 0.2 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.11 EJS44642.1 - 3.8e-05 23.5 0.0 0.00014 21.7 0.0 2.1 1 1 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Ala_racemase_N PF01168.15 EJS44643.1 - 9.2e-38 129.9 0.0 1.1e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Pol_alpha_B_N PF08418.5 EJS44644.1 - 7.1e-80 268.1 11.2 1.1e-79 267.5 7.8 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EJS44644.1 - 1.2e-59 201.0 0.4 2e-59 200.3 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Mito_carr PF00153.22 EJS44646.1 - 7.7e-70 230.6 4.9 1.1e-23 82.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-LITAF-like PF10601.4 EJS44647.1 - 0.0032 17.2 0.1 0.0048 16.7 0.1 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-Mss51 PF13824.1 EJS44647.1 - 0.013 15.3 3.1 0.33 10.8 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-CHY PF05495.7 EJS44647.1 - 0.17 12.0 1.7 2.8 8.1 1.3 2.0 1 1 1 2 2 2 0 CHY zinc finger RecR PF02132.10 EJS44647.1 - 0.21 11.0 2.2 2 7.8 0.1 2.2 2 0 0 2 2 2 0 RecR protein Cys_rich_CPCC PF14206.1 EJS44647.1 - 1.6 8.3 5.5 0.63 9.6 0.2 2.3 2 1 1 3 3 3 0 Cysteine-rich CPCC Zn_Tnp_IS1595 PF12760.2 EJS44647.1 - 1.7 8.5 4.6 10 6.0 2.4 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Pheromone PF08015.6 EJS44648.1 - 7.5 7.4 22.5 0.22 12.3 1.9 3.1 3 1 0 3 3 3 0 Fungal mating-type pheromone DUF2423 PF10338.4 EJS44649.1 - 4.4e-21 74.5 5.9 4.4e-21 74.5 4.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) Med12-LCEWAV PF12145.3 EJS44649.1 - 0.082 11.3 3.8 0.095 11.1 2.7 1.0 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain MSC PF09402.5 EJS44649.1 - 0.13 10.9 2.7 0.14 10.8 1.8 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain YlqD PF11068.3 EJS44649.1 - 1.2 9.1 8.2 1.6 8.8 5.7 1.2 1 0 0 1 1 1 0 YlqD protein UAF_Rrn10 PF05234.6 EJS44650.1 - 4.5e-66 220.3 0.3 5.4e-66 220.0 0.2 1.0 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Nol1_Nop2_Fmu PF01189.12 EJS44651.1 - 1.7e-124 414.8 0.1 1.2e-107 359.5 0.0 2.1 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 EJS44651.1 - 0.00031 20.7 0.0 0.0007 19.6 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EJS44651.1 - 0.026 15.0 0.0 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EJS44651.1 - 0.028 13.4 0.0 0.061 12.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MCM PF00493.18 EJS44652.1 - 1.9e-141 470.7 3.1 9.3e-141 468.4 2.2 1.9 1 1 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EJS44652.1 - 3.7e-29 101.7 33.5 3.7e-29 101.7 23.2 3.8 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EJS44652.1 - 6.6e-14 52.4 0.1 1.8e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EJS44652.1 - 2.6e-09 36.5 0.0 2.4e-07 30.1 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EJS44652.1 - 1.7e-07 31.0 0.0 4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EJS44652.1 - 0.0003 20.4 0.0 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EJS44652.1 - 0.0013 18.2 0.1 0.0079 15.6 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 EJS44652.1 - 0.011 15.9 0.0 0.044 13.9 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cut8_N PF14482.1 EJS44652.1 - 0.49 10.4 9.9 0.088 12.8 2.7 2.5 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Lon_C PF05362.8 EJS44653.1 - 2.4e-66 222.9 0.0 1.1e-65 220.8 0.0 2.2 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EJS44653.1 - 3.2e-36 124.9 9.8 3.8e-35 121.4 6.8 2.6 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EJS44653.1 - 2.7e-22 79.3 0.0 7.1e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EJS44653.1 - 2.7e-08 33.8 0.0 2.9e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EJS44653.1 - 4e-07 29.8 0.0 1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EJS44653.1 - 9e-07 28.4 0.0 3.4e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 EJS44653.1 - 6.1e-05 23.1 0.0 0.0018 18.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EJS44653.1 - 0.00012 22.9 3.9 0.00022 22.0 0.0 3.5 4 0 0 4 4 2 1 AAA domain AAA_16 PF13191.1 EJS44653.1 - 0.00037 20.5 0.7 0.0071 16.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 EJS44653.1 - 0.0012 19.1 3.0 0.0067 16.7 0.0 3.5 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EJS44653.1 - 0.0015 18.6 0.0 0.068 13.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 EJS44653.1 - 0.0022 17.9 0.0 0.012 15.4 0.0 2.3 2 1 1 3 3 2 1 AAA domain SKI PF01202.17 EJS44653.1 - 0.008 16.0 0.5 0.027 14.3 0.0 2.2 2 0 0 2 2 1 1 Shikimate kinase RuvB_N PF05496.7 EJS44653.1 - 0.013 14.5 0.0 0.07 12.1 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 EJS44653.1 - 0.015 14.9 0.5 0.49 10.0 0.0 3.0 2 1 1 3 3 3 0 NTPase DUF258 PF03193.11 EJS44653.1 - 0.05 12.7 0.2 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EJS44653.1 - 0.07 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Herpes_LMP1 PF05297.6 EJS44653.1 - 9.5 5.0 9.8 14 4.4 6.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) CBFD_NFYB_HMF PF00808.18 EJS44654.1 - 7.8e-25 86.7 0.0 1.1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EJS44654.1 - 3.5e-06 27.0 0.0 5.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Rft-1 PF04506.8 EJS44655.1 - 2e-225 749.3 39.1 2.3e-225 749.1 27.1 1.0 1 0 0 1 1 1 1 Rft protein Exo_endo_phos PF03372.18 EJS44656.1 - 1.3e-14 54.7 0.0 2.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EJS44656.1 - 1.3e-12 47.3 0.0 5e-11 42.2 0.0 2.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EJS44656.1 - 1e-10 41.3 2.1 2.5e-10 40.1 1.5 1.7 1 0 0 1 1 1 1 GRF zinc finger BNR PF02012.15 EJS44657.1 - 1.3e-14 51.6 46.5 0.12 12.2 0.2 13.4 13 0 0 13 13 13 9 BNR/Asp-box repeat BNR_2 PF13088.1 EJS44657.1 - 2.2e-05 23.9 8.0 0.57 9.4 0.1 6.2 5 2 0 5 5 5 2 BNR repeat-like domain PSII_BNR PF14870.1 EJS44657.1 - 0.0016 17.4 2.2 1 8.2 0.1 4.8 4 1 1 5 5 5 1 Photosynthesis system II assembly factor YCF48 CHB_HEX_C_1 PF13290.1 EJS44657.1 - 0.28 10.9 4.3 1.7 8.4 0.3 3.6 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain Mo-co_dimer PF03404.11 EJS44657.1 - 1.8 8.2 9.9 9.6 5.8 0.1 5.3 6 1 0 6 6 6 0 Mo-co oxidoreductase dimerisation domain Pkinase PF00069.20 EJS44658.1 - 1.5e-72 243.9 0.0 1.8e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44658.1 - 1.7e-31 109.2 0.0 2.3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS44658.1 - 0.0026 16.7 0.0 0.013 14.5 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EJS44658.1 - 0.042 12.9 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EJS44658.1 - 0.046 13.4 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AcetylCoA_hydro PF02550.10 EJS44659.1 - 3.6e-78 261.8 0.1 1.1e-77 260.2 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EJS44659.1 - 2.4e-38 131.2 0.0 3.6e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.7 EJS44659.1 - 0.0043 15.7 0.1 0.01 14.5 0.1 1.5 1 1 0 1 1 1 1 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.18 EJS44659.1 - 0.076 12.1 0.0 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 Coenzyme A transferase Cid2 PF09774.4 EJS44660.1 - 1.1e-37 129.4 5.6 1.3e-37 129.1 3.9 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 LPP20 PF02169.11 EJS44660.1 - 0.05 13.6 1.5 0.085 12.9 1.1 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein Lgl_C PF08596.5 EJS44661.1 - 1.8e-146 487.6 0.8 1.7e-145 484.4 0.0 2.5 2 1 1 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EJS44661.1 - 0.00075 19.2 2.3 4.4 7.3 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Pkinase PF00069.20 EJS44662.1 - 2.8e-64 216.7 0.0 2e-63 214.0 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44662.1 - 5.4e-36 123.9 0.0 1.3e-35 122.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EJS44662.1 - 2.3e-24 84.9 25.8 2.2e-13 49.7 6.2 3.3 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 EJS44662.1 - 4.8e-20 71.0 36.9 1.1e-10 41.0 10.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EJS44662.1 - 3.4e-12 46.7 3.1 3.4e-12 46.7 2.1 2.7 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EJS44662.1 - 0.00083 18.4 0.6 0.002 17.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like FliC PF12445.3 EJS44662.1 - 0.021 14.9 4.2 0.6 10.2 0.3 2.7 2 0 0 2 2 2 0 Flagellin protein zf-tcix PF14952.1 EJS44662.1 - 3.2 7.1 11.1 0.51 9.7 1.2 2.7 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding DUF4206 PF13901.1 EJS44662.1 - 4.2 6.8 30.4 0.56 9.7 4.9 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4206) SopA PF13981.1 EJS44663.1 - 0.025 14.5 0.0 0.089 12.8 0.0 1.9 2 0 0 2 2 2 0 SopA-like central domain HLH PF00010.21 EJS44664.1 - 4.8e-13 48.5 0.3 1e-12 47.5 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain 3H PF02829.9 EJS44664.1 - 0.029 14.3 0.3 0.085 12.8 0.2 1.8 1 0 0 1 1 1 0 3H domain Got1 PF04178.7 EJS44665.1 - 7.7e-30 103.4 18.5 1e-29 102.9 12.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family ABC2_membrane_3 PF12698.2 EJS44665.1 - 5.7 5.8 18.8 6 5.8 12.5 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein NfeD PF01957.13 EJS44665.1 - 6.4 6.9 8.2 0.72 9.9 2.3 1.8 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Arrestin_C PF02752.17 EJS44666.1 - 1.2e-14 54.5 0.3 1.2e-14 54.5 0.2 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain MFS_1 PF07690.11 EJS44667.1 - 1.9e-29 102.4 15.4 2.7e-29 101.9 10.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cornichon PF03311.9 EJS44668.1 - 2.3e-47 160.3 7.6 2.6e-47 160.1 5.3 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 EJS44668.1 - 0.05 13.2 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) APG6 PF04111.7 EJS44669.1 - 0.0066 15.5 2.7 0.011 14.7 1.8 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 DivIC PF04977.10 EJS44669.1 - 0.64 9.5 6.1 0.57 9.7 2.4 2.3 2 1 0 2 2 2 0 Septum formation initiator DASH_Dad3 PF08656.5 EJS44669.1 - 2 8.1 7.1 29 4.4 1.9 3.6 2 1 2 4 4 4 0 DASH complex subunit Dad3 NAD_binding_7 PF13241.1 EJS44670.1 - 4.4e-26 91.1 0.0 8.5e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EJS44670.1 - 1.6e-24 84.9 0.0 4.1e-24 83.6 0.0 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EJS44670.1 - 5.4e-15 54.0 0.1 1.8e-14 52.3 0.1 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 EJS44670.1 - 0.036 14.1 0.1 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EJS44670.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CBS PF00571.23 EJS44671.1 - 3.7e-22 77.8 0.2 0.00052 19.7 0.0 5.5 5 0 0 5 5 5 5 CBS domain Kinetochor_Ybp2 PF08568.5 EJS44672.1 - 1.3e-151 505.9 11.3 1.6e-151 505.7 7.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin APG12 PF04110.8 EJS44673.1 - 2.1e-35 120.7 0.5 5.2e-35 119.4 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 DUF2575 PF10837.3 EJS44673.1 - 0.054 13.5 0.1 0.092 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) DUF4368 PF14287.1 EJS44673.1 - 0.082 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) CPSase_L_D2 PF02786.12 EJS44674.1 - 7.4e-84 280.2 0.1 1.4e-83 279.3 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EJS44674.1 - 5.4e-67 225.0 0.0 8.4e-67 224.4 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EJS44674.1 - 1.2e-35 121.9 0.0 2.9e-35 120.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EJS44674.1 - 5.6e-31 106.7 0.0 2.2e-30 104.7 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EJS44674.1 - 1.4e-28 100.1 0.0 3.7e-28 98.7 0.0 1.7 1 0 0 1 1 1 1 HMGL-like ATPgrasp_Ter PF15632.1 EJS44674.1 - 1.5e-18 66.6 0.0 8.4e-18 64.1 0.0 2.2 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EJS44674.1 - 1.5e-18 66.1 5.2 1.5e-18 66.1 3.6 2.7 3 0 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EJS44674.1 - 3.2e-15 56.3 0.1 6.7e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EJS44674.1 - 5e-09 35.6 3.5 0.0011 18.6 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EJS44674.1 - 1.9e-07 30.6 0.0 4.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EJS44674.1 - 1.5e-06 27.7 0.0 3.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EJS44674.1 - 2.3e-05 24.3 0.0 5.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EJS44674.1 - 0.00041 19.8 0.0 0.0014 18.0 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 EJS44674.1 - 0.0032 16.6 0.8 1.3 8.0 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 EJS44674.1 - 0.012 14.9 1.9 0.11 11.7 0.0 2.6 3 0 0 3 3 3 0 HlyD family secretion protein HlyD_3 PF13437.1 EJS44674.1 - 0.022 15.1 1.3 6.8 7.0 0.0 3.4 3 0 0 3 3 3 0 HlyD family secretion protein RnfC_N PF13375.1 EJS44674.1 - 0.049 13.3 4.4 0.5 10.1 1.4 2.9 3 0 0 3 3 2 0 RnfC Barrel sandwich hybrid domain Acatn PF13000.2 EJS44675.1 - 0 1029.2 18.6 0 1029.0 12.9 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Transket_pyr PF02779.19 EJS44676.1 - 3.9e-47 160.0 0.0 1.1e-46 158.5 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EJS44676.1 - 7.8e-37 125.9 0.1 1.5e-36 125.0 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain AMP-binding PF00501.23 EJS44677.1 - 7.8e-72 241.9 0.0 1.4e-71 241.0 0.0 1.3 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 EJS44677.1 - 4.7e-17 62.6 0.4 1.9e-16 60.7 0.0 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain NSP11 PF06471.7 EJS44677.1 - 0.034 12.3 0.0 0.057 11.6 0.0 1.3 1 0 0 1 1 1 0 NSP11 Tyr-DNA_phospho PF06087.7 EJS44678.1 - 2.5e-106 355.9 0.0 2.9e-106 355.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EJS44678.1 - 0.0012 18.5 0.0 0.056 13.2 0.0 2.5 2 0 0 2 2 2 1 PLD-like domain Methyltransf_11 PF08241.7 EJS44679.1 - 0.014 15.8 0.0 0.069 13.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain GIY-YIG PF01541.19 EJS44680.1 - 1.2e-09 38.3 0.2 3.8e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EJS44680.1 - 6.9e-06 25.9 4.2 2.2e-05 24.3 2.9 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain DUF329 PF03884.9 EJS44680.1 - 0.0037 16.7 0.4 3.2 7.3 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF329) zf-RING-like PF08746.6 EJS44680.1 - 0.0086 16.0 1.5 0.0086 16.0 1.1 2.7 3 0 0 3 3 3 1 RING-like domain zinc_ribbon_5 PF13719.1 EJS44680.1 - 0.027 14.0 1.9 6 6.5 0.2 3.1 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EJS44680.1 - 0.059 13.0 2.1 4.6 7.0 0.2 3.1 2 1 0 2 2 2 0 zinc-ribbon domain T5orf172 PF10544.4 EJS44680.1 - 0.092 13.1 0.2 0.32 11.4 0.1 2.0 1 1 0 1 1 1 0 T5orf172 domain zf-rbx1 PF12678.2 EJS44680.1 - 0.28 11.2 3.8 1.2 9.2 0.8 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EJS44680.1 - 0.32 10.8 9.0 0.05 13.4 3.4 1.8 2 0 0 2 2 2 0 Ring finger domain Glyco_hydro_31 PF01055.21 EJS44681.1 - 3.5e-143 477.6 1.1 5.1e-143 477.0 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EJS44681.1 - 1.4e-20 72.8 0.4 5.1e-20 71.1 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like DUF1470 PF07336.6 EJS44682.1 - 0.057 13.7 1.2 0.064 13.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) TPR_6 PF13174.1 EJS44682.1 - 0.22 12.0 1.4 0.71 10.4 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat KH_1 PF00013.24 EJS44683.1 - 1.9e-36 123.4 1.8 9.5e-11 41.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EJS44683.1 - 3.6e-25 87.1 7.2 1.2e-07 31.1 0.5 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EJS44683.1 - 2.8e-10 39.5 0.2 0.036 13.6 0.0 3.7 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EJS44683.1 - 1.8e-07 30.6 0.4 0.017 14.7 0.0 3.1 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EJS44683.1 - 0.064 13.0 1.8 16 5.4 0.0 3.4 3 0 0 3 3 3 0 NusA-like KH domain WD40 PF00400.27 EJS44684.1 - 1.8e-15 56.1 10.8 0.00014 21.6 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EJS44684.1 - 0.00096 18.9 0.1 0.052 13.2 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Rax2 PF12768.2 EJS44684.1 - 0.0035 16.5 0.2 0.0063 15.7 0.1 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity AA_permease PF00324.16 EJS44685.1 - 8.2e-44 149.7 40.1 8.2e-44 149.7 27.8 1.4 2 0 0 2 2 2 1 Amino acid permease Zip PF02535.17 EJS44686.1 - 0.21 10.5 14.9 0.35 9.8 10.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PAS PF00989.19 EJS44687.1 - 4e-18 65.2 0.0 6.4e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 EJS44687.1 - 1.6e-05 24.6 11.0 3.3e-05 23.6 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 EJS44687.1 - 0.0026 18.1 0.0 0.0088 16.3 0.0 1.9 1 0 0 1 1 1 1 PAS domain CpeT PF06206.6 EJS44687.1 - 0.082 12.5 0.2 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 CpeT/CpcT family (DUF1001) PAS_8 PF13188.1 EJS44687.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 EJS44687.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 PAS fold Zn_clus PF00172.13 EJS44688.1 - 2e-11 43.6 6.0 2e-11 43.6 4.1 2.7 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YjbE PF11106.3 EJS44688.1 - 0.019 14.8 3.1 0.032 14.1 2.2 1.3 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Adeno_E1A PF02703.9 EJS44688.1 - 1 8.7 6.9 15 4.9 3.0 2.4 2 0 0 2 2 2 0 Early E1A protein Sugar_tr PF00083.19 EJS44689.1 - 9.6e-112 373.8 24.4 1.2e-111 373.5 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EJS44689.1 - 4.3e-28 98.0 34.1 4.7e-28 97.9 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glycos_transf_4 PF00953.16 EJS44690.1 - 4.4e-32 111.0 9.6 4.4e-32 111.0 6.6 2.3 3 1 0 3 3 3 1 Glycosyl transferase family 4 GSHPx PF00255.14 EJS44691.1 - 1.2e-49 166.1 2.1 1.6e-49 165.7 1.4 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EJS44691.1 - 9.6e-07 28.5 0.5 5.3e-06 26.1 0.4 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EJS44691.1 - 8.2e-06 25.4 0.2 4.1e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 EJS44691.1 - 0.016 14.8 0.2 0.077 12.6 0.1 1.9 2 0 0 2 2 2 0 SCO1/SenC WD40 PF00400.27 EJS44692.1 - 2.5e-07 30.2 3.5 0.064 13.1 0.0 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF2415 PF10313.4 EJS44692.1 - 0.11 12.2 0.0 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Bystin PF05291.6 EJS44693.1 - 7.5e-121 402.7 0.0 1.2e-120 402.0 0.0 1.3 1 0 0 1 1 1 1 Bystin DnaB_2 PF07261.6 EJS44693.1 - 0.018 14.6 0.1 0.061 12.9 0.0 1.9 2 0 0 2 2 2 0 Replication initiation and membrane attachment DAHP_synth_1 PF00793.15 EJS44694.1 - 3e-105 350.7 0.0 3.8e-105 350.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_S5 PF00333.15 EJS44695.1 - 4e-25 87.3 1.1 4.8e-25 87.0 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EJS44695.1 - 1.1e-17 63.1 0.0 1.8e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain dUTPase PF00692.14 EJS44696.1 - 2.2e-44 150.0 0.1 2.5e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 dUTPase FtsZ_C PF12327.3 EJS44696.1 - 0.065 13.3 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 FtsZ family, C-terminal domain Med22 PF06179.7 EJS44697.1 - 2.4e-23 82.2 6.9 2.8e-23 82.0 4.8 1.0 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex TMCO5 PF14992.1 EJS44697.1 - 0.022 13.8 4.8 0.027 13.6 3.4 1.1 1 0 0 1 1 1 0 TMCO5 family SAM_decarbox PF01536.11 EJS44697.1 - 0.025 13.2 0.1 0.027 13.1 0.1 1.1 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Sedlin_N PF04628.8 EJS44698.1 - 4.3e-50 168.9 0.0 5e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EJS44698.1 - 2.3e-07 30.6 0.2 4.1e-07 29.7 0.1 1.7 1 1 0 1 1 1 1 Sybindin-like family Lum_binding PF00677.12 EJS44700.1 - 4.6e-53 177.0 6.8 1.1e-26 92.4 0.9 2.3 2 0 0 2 2 2 2 Lumazine binding domain NigD PF12667.2 EJS44700.1 - 0.13 12.0 1.4 0.23 11.2 0.3 1.8 2 0 0 2 2 2 0 NigD-like protein UPF0086 PF01868.11 EJS44701.1 - 4e-14 52.0 0.0 7.3e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Methyltransf_PK PF05891.7 EJS44703.1 - 5.5e-99 329.8 0.0 6.2e-99 329.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EJS44703.1 - 1e-07 31.8 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS44703.1 - 2.9e-05 24.6 0.0 4.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EJS44703.1 - 0.00084 19.7 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EJS44703.1 - 0.015 14.4 0.2 0.052 12.7 0.1 1.7 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_25 PF13649.1 EJS44703.1 - 0.019 15.3 0.0 0.034 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EJS44703.1 - 0.087 12.2 0.0 0.18 11.1 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Secretin_N_2 PF07655.8 EJS44703.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain SHMT PF00464.14 EJS44705.1 - 6.4e-209 693.2 0.0 7.5e-209 693.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EJS44705.1 - 0.016 14.1 0.0 0.035 13.0 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class I and II Ras PF00071.17 EJS44706.1 - 7e-40 136.0 0.0 8.5e-40 135.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EJS44706.1 - 7.8e-17 61.8 0.0 1.3e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EJS44706.1 - 9.2e-11 41.2 0.0 1.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EJS44706.1 - 8.8e-08 31.8 0.3 6.5e-07 28.9 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EJS44706.1 - 3.3e-07 29.7 0.0 5.1e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EJS44706.1 - 0.00043 20.2 0.0 0.0006 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EJS44706.1 - 0.004 15.8 0.1 4.5 5.8 0.0 3.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EJS44706.1 - 0.058 12.6 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EJS44706.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EJS44706.1 - 0.073 12.3 0.0 1.6 8.0 0.0 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 EJS44706.1 - 0.11 12.6 0.0 0.71 10.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain adh_short PF00106.20 EJS44707.1 - 3.7e-18 65.9 0.0 2.2e-17 63.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EJS44707.1 - 3.3e-09 36.6 0.0 5.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EJS44707.1 - 0.0011 17.9 0.0 0.002 17.0 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EJS44707.1 - 0.0017 18.1 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-C2H2_2 PF12756.2 EJS44708.1 - 2.1e-33 114.4 3.2 7.1e-31 106.3 1.0 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Stap_Strp_tox_C PF02876.12 EJS44708.1 - 0.12 12.5 2.9 0.24 11.5 2.0 1.5 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain DDHD PF02862.12 EJS44708.1 - 5.8 6.6 8.4 4.7 6.9 4.6 1.7 2 0 0 2 2 2 0 DDHD domain Ribosomal_L37 PF08561.5 EJS44709.1 - 4.2e-28 96.7 0.7 5e-28 96.4 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Crystall_3 PF08964.5 EJS44709.1 - 0.071 12.8 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF1674 PF07896.7 EJS44710.1 - 3.6e-17 62.2 0.7 5.2e-17 61.7 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) HbrB PF08539.6 EJS44711.1 - 8e-38 129.7 1.2 1.2e-37 129.1 0.8 1.3 1 0 0 1 1 1 1 HbrB-like Pet20 PF08692.5 EJS44711.1 - 0.0012 18.7 0.1 0.0035 17.2 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial protein Pet20 DUF1296 PF06972.6 EJS44711.1 - 0.075 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Methyltransf_16 PF10294.4 EJS44712.1 - 1.3e-25 89.8 0.0 1.9e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EJS44712.1 - 1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS44712.1 - 8.1e-06 26.3 0.0 1.9e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EJS44712.1 - 3.2e-05 23.6 0.0 8.6e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EJS44712.1 - 0.0015 17.9 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EJS44712.1 - 0.004 17.5 0.0 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EJS44712.1 - 0.0076 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EJS44712.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EJS44712.1 - 0.028 13.3 0.0 0.053 12.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_11 PF08241.7 EJS44712.1 - 0.056 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EJS44713.1 - 1.3e-59 201.5 0.0 1.6e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44713.1 - 1e-33 116.5 0.0 1.4e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS44713.1 - 1e-06 27.9 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EJS44713.1 - 0.0053 15.6 0.1 0.015 14.1 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Choline_kinase PF01633.15 EJS44713.1 - 0.021 14.3 0.1 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 EJS44713.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSPc PF00782.15 EJS44714.1 - 8.3e-27 93.3 0.0 4.8e-21 74.7 0.0 3.5 2 1 1 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EJS44714.1 - 6.2e-06 25.7 0.1 4e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EJS44714.1 - 0.0075 16.3 0.4 0.016 15.2 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate RCC1_2 PF13540.1 EJS44715.1 - 4.3e-18 64.4 10.8 7.5e-10 38.1 1.4 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EJS44715.1 - 4.1e-16 58.9 4.3 2.3e-05 24.5 0.3 6.2 6 1 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Peptidase_M20 PF01546.23 EJS44716.1 - 7.8e-20 71.1 0.0 1.5e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EJS44716.1 - 1.3e-15 57.1 0.0 2.4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.27 EJS44716.1 - 6.7e-12 44.8 6.0 0.00061 19.5 0.0 6.1 5 1 0 5 5 5 4 WD domain, G-beta repeat MRP-L27 PF09809.4 EJS44717.1 - 2.3e-30 104.4 0.2 3.4e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SecY PF00344.15 EJS44718.1 - 4.1e-56 190.3 24.9 5.5e-56 189.9 17.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EJS44718.1 - 8.7e-09 34.7 0.0 3.1e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p A_deaminase PF00962.17 EJS44719.1 - 6.1e-19 68.1 0.0 1.2e-12 47.4 0.0 2.5 2 1 0 2 2 2 2 Adenosine/AMP deaminase Sld5 PF05916.6 EJS44719.1 - 0.037 14.3 0.4 1.3 9.3 0.0 3.0 2 0 0 2 2 2 0 GINS complex protein Peptidase_M28 PF04389.12 EJS44721.1 - 2.6e-36 125.0 0.0 4e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EJS44721.1 - 5.3e-12 45.3 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EJS44721.1 - 0.0019 17.7 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EJS44721.1 - 0.011 14.4 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Mem_trans PF03547.13 EJS44722.1 - 3.3e-71 239.6 11.5 4.5e-71 239.1 8.0 1.2 1 0 0 1 1 1 1 Membrane transport protein CcoS PF03597.10 EJS44722.1 - 0.65 9.4 5.6 5.3 6.5 0.3 3.5 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Adap_comp_sub PF00928.16 EJS44723.1 - 3.8e-41 140.9 0.3 5.6e-41 140.3 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family DUF3947 PF13135.1 EJS44723.1 - 0.19 11.9 3.0 0.38 10.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Mito_carr PF00153.22 EJS44724.1 - 4.3e-67 221.8 1.6 1e-22 79.6 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EJS44724.1 - 0.0072 16.3 1.0 4 7.5 0.0 3.5 2 1 2 4 4 4 2 Tim17/Tim22/Tim23/Pmp24 family PHO4 PF01384.15 EJS44725.1 - 8.2e-120 399.3 5.3 1.3e-119 398.7 3.7 1.3 1 1 0 1 1 1 1 Phosphate transporter family Tautomerase PF01361.16 EJS44725.1 - 0.014 15.0 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 Tautomerase enzyme SRF-TF PF00319.13 EJS44726.1 - 1.2e-24 85.3 0.1 1.2e-24 85.3 0.1 2.0 3 0 0 3 3 3 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MBA1 PF07961.6 EJS44727.1 - 6.3e-109 362.3 1.0 7.6e-109 362.0 0.7 1.0 1 0 0 1 1 1 1 MBA1-like protein UPF0016 PF01169.14 EJS44728.1 - 2.2e-38 130.2 31.6 2.7e-21 75.4 4.9 2.5 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 ISG65-75 PF11727.3 EJS44728.1 - 0.067 12.2 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF1673 PF07895.6 EJS44728.1 - 0.085 12.3 0.1 0.085 12.3 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) DUF2448 PF10476.4 EJS44728.1 - 0.71 9.3 4.9 0.76 9.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) cwf18 PF08315.7 EJS44729.1 - 0.015 15.7 8.3 0.054 13.9 5.8 1.8 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor Cas_Csy4 PF09618.5 EJS44729.1 - 0.088 12.6 1.9 0.11 12.3 1.3 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DUF771 PF05595.6 EJS44729.1 - 0.17 11.8 1.1 0.34 10.8 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF771) Mito_carr PF00153.22 EJS44730.1 - 2.2e-77 254.8 3.2 3e-29 100.5 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PGI PF00342.14 EJS44731.1 - 2.8e-227 754.9 1.7 3.8e-227 754.4 1.2 1.2 1 0 0 1 1 1 1 Phosphoglucose isomerase WD40 PF00400.27 EJS44732.1 - 7.9e-62 203.0 20.3 1.1e-11 44.1 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EJS44732.1 - 1.1e-49 168.2 0.9 2.4e-49 167.0 0.6 1.6 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EJS44732.1 - 1e-06 27.2 2.4 0.013 13.6 0.1 3.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 LisH PF08513.6 EJS44732.1 - 1.2e-06 28.0 0.1 3e-06 26.7 0.1 1.8 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 EJS44732.1 - 0.0001 21.2 0.6 0.033 12.9 0.4 3.3 1 1 0 1 1 1 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 EJS44732.1 - 0.0041 15.4 0.1 0.18 10.0 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain DUF4220 PF13968.1 EJS44732.1 - 1.2 8.1 3.5 2.9 6.9 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Glyco_transf_15 PF01793.11 EJS44733.1 - 2.1e-119 398.3 13.6 2.7e-119 397.9 9.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SH3_1 PF00018.23 EJS44734.1 - 1.7e-25 88.1 0.0 1.6e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 SH3 domain PX PF00787.19 EJS44734.1 - 3.9e-18 65.2 0.0 7.2e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 EJS44734.1 - 2e-14 52.8 0.8 7.6e-11 41.4 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.19 EJS44734.1 - 3.8e-09 36.0 0.0 1.1e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 PB1 domain SH3_2 PF07653.12 EJS44734.1 - 8e-08 31.6 0.0 4.2e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Ebp2 PF05890.7 EJS44734.1 - 0.03 13.6 0.0 0.061 12.6 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 DER1 PF04511.10 EJS44735.1 - 1.9e-46 158.0 10.9 2.2e-46 157.8 7.6 1.0 1 0 0 1 1 1 1 Der1-like family RVT_1 PF00078.22 EJS44735.1 - 0.077 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MCM PF00493.18 EJS44737.1 - 6.7e-134 445.8 0.0 1.4e-133 444.8 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EJS44737.1 - 5.6e-25 88.1 3.2 3.3e-24 85.6 2.2 2.4 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EJS44737.1 - 9.5e-08 31.4 0.0 1.1e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EJS44737.1 - 1.6e-06 27.8 0.0 6.8e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EJS44737.1 - 0.00041 20.6 0.2 0.0021 18.3 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EJS44737.1 - 0.039 13.4 0.0 0.6 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 EJS44737.1 - 0.058 12.9 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FTR1 PF03239.9 EJS44738.1 - 4.1e-113 377.3 3.3 4.7e-113 377.1 2.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family CASP_C PF08172.7 EJS44738.1 - 0.73 8.8 4.0 1.4 7.8 2.8 1.4 1 0 0 1 1 1 0 CASP C terminal Amidase PF01425.16 EJS44739.1 - 3.5e-99 332.6 0.0 4.7e-99 332.2 0.0 1.2 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 EJS44739.1 - 3.3e-85 285.6 0.0 9e-85 284.2 0.0 1.8 2 0 0 2 2 2 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EJS44739.1 - 6.5e-63 211.8 0.0 1.2e-62 210.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 EJS44739.1 - 1.9e-42 145.0 0.0 3.7e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 EJS44739.1 - 1.9e-38 130.9 0.0 5.9e-38 129.3 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EJS44739.1 - 1.6e-31 108.4 0.0 3.6e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EJS44739.1 - 5.4e-19 67.5 0.4 1.7e-18 66.0 0.3 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EJS44739.1 - 4.2e-18 65.7 0.0 9.2e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EJS44739.1 - 8.4e-12 44.9 0.0 1.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EJS44739.1 - 2.8e-06 26.9 0.0 1.1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EJS44739.1 - 1.1e-05 24.8 0.0 3.2e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EJS44739.1 - 0.00068 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 EJS44739.1 - 0.0081 15.3 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 EJS44739.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Toxin_59 PF15537.1 EJS44739.1 - 0.16 12.0 0.4 1.4 9.0 0.0 2.6 3 0 0 3 3 3 0 Putative toxin 59 Ribosomal_L31 PF01197.13 EJS44741.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L31 YqzE PF14038.1 EJS44741.1 - 0.13 12.0 1.5 0.18 11.5 0.2 1.8 2 0 0 2 2 2 0 YqzE-like protein PP2C PF00481.16 EJS44742.1 - 8.7e-72 241.5 0.0 6e-68 228.9 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EJS44742.1 - 2.7e-06 26.9 0.0 6.6e-05 22.4 0.0 2.6 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 EJS44742.1 - 0.0022 17.7 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Glyco_transf_20 PF00982.16 EJS44743.1 - 4e-202 671.8 0.1 4.5e-202 671.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EJS44743.1 - 9e-05 21.9 0.4 0.1 12.0 0.1 3.1 2 1 0 2 2 2 2 Glycosyl transferases group 1 ATP-synt_ab PF00006.20 EJS44744.1 - 4.7e-61 206.0 0.0 7.2e-61 205.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EJS44744.1 - 3.9e-16 59.5 0.2 8e-16 58.5 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EJS44744.1 - 1.1e-14 54.3 1.2 2.5e-14 53.2 0.8 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EJS44744.1 - 0.00012 21.9 0.5 0.00035 20.4 0.3 1.9 1 0 0 1 1 1 1 HAS barrel domain Atg14 PF10186.4 EJS44745.1 - 4.3e-55 186.7 3.1 5.4e-55 186.4 2.2 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 EJS44745.1 - 0.02 13.3 3.9 0.025 13.0 2.7 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 EJS44745.1 - 0.021 14.9 4.1 0.021 14.9 2.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.7 EJS44745.1 - 0.34 10.6 4.6 0.32 10.7 2.2 1.7 1 1 1 2 2 2 0 Laminin Domain II bZIP_2 PF07716.10 EJS44745.1 - 5.5 6.8 10.0 11 5.9 1.6 2.7 2 1 0 2 2 2 0 Basic region leucine zipper PH PF00169.24 EJS44746.1 - 2.8e-07 30.7 6.2 0.00024 21.2 0.6 2.5 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 EJS44746.1 - 8.2e-05 22.8 3.2 0.045 13.9 0.0 2.9 2 1 1 3 3 3 2 Pleckstrin homology domain DUF1712 PF08217.6 EJS44747.1 - 3.2e-198 659.8 26.5 3.7e-198 659.6 18.3 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) AA_permease PF00324.16 EJS44748.1 - 4.8e-134 447.2 24.1 5.5e-134 447.0 16.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS44748.1 - 1.1e-25 90.1 28.1 1.3e-25 89.8 19.5 1.1 1 0 0 1 1 1 1 Amino acid permease PRMT5 PF05185.11 EJS44749.1 - 7e-153 509.7 2.9 8.7e-153 509.4 2.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CKS PF01111.14 EJS44750.1 - 8.5e-36 121.6 0.1 1.3e-35 120.9 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF3464 PF11947.3 EJS44750.1 - 0.98 8.8 4.3 1.3 8.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) PI3_PI4_kinase PF00454.22 EJS44751.1 - 9e-55 185.6 0.2 2.9e-54 184.0 0.1 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 EJS44751.1 - 1.5e-33 114.9 4.8 1.8e-33 114.7 0.2 3.7 4 0 0 4 4 4 1 UME (NUC010) domain FATC PF02260.15 EJS44751.1 - 8.8e-15 53.8 0.1 1.9e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 FATC domain FAT PF02259.18 EJS44751.1 - 7.1e-12 44.9 6.5 7.1e-12 44.9 4.5 3.1 3 0 0 3 3 3 1 FAT domain TPR_19 PF14559.1 EJS44751.1 - 0.092 13.0 0.0 0.56 10.5 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_21 PF09976.4 EJS44751.1 - 0.32 10.9 0.0 1.1 9.1 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF336 PF03928.9 EJS44752.1 - 2.5e-28 98.5 0.0 2.8e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) RasGAP PF00616.14 EJS44753.1 - 8.1e-37 126.7 1.2 4.2e-36 124.4 0.3 2.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF3321 PF11968.3 EJS44754.1 - 2.2e-75 253.0 0.0 3e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EJS44754.1 - 3.5e-07 30.0 0.0 8.9e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EJS44754.1 - 0.0046 17.4 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EJS44754.1 - 0.043 13.4 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_31 PF13847.1 EJS44754.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain eRF1_2 PF03464.10 EJS44755.1 - 1.1e-44 151.9 0.1 1.8e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EJS44755.1 - 2.9e-38 130.6 0.2 6.6e-38 129.4 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EJS44755.1 - 2.3e-27 95.1 0.1 4e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 ADH_N PF08240.7 EJS44756.1 - 2e-30 104.7 2.1 2.3e-30 104.5 0.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EJS44756.1 - 9.2e-30 102.8 0.4 1.3e-29 102.3 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EJS44756.1 - 0.00027 21.8 0.0 0.0007 20.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF539 PF04400.8 EJS44756.1 - 0.09 12.2 0.2 0.09 12.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF539) Ribosomal_S9 PF00380.14 EJS44757.1 - 3.6e-38 130.5 0.2 5.6e-38 129.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PQ-loop PF04193.9 EJS44758.1 - 8.2e-41 137.3 11.2 1.4e-22 78.9 2.0 3.1 4 0 0 4 4 4 2 PQ loop repeat Steroid_dh PF02544.11 EJS44758.1 - 0.14 11.9 1.6 0.25 11.0 0.2 2.1 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase MtN3_slv PF03083.11 EJS44758.1 - 3.5 7.5 7.9 0.96 9.3 0.7 2.9 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Aldo_ket_red PF00248.16 EJS44759.1 - 4.2e-40 137.3 0.0 5e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Suc_Fer-like PF06999.7 EJS44760.1 - 4.3e-59 200.3 0.0 5.2e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Prp19_bind PF06991.6 EJS44761.1 - 0.0013 18.0 28.0 0.0013 18.0 19.4 2.0 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain RNA_pol_Rpb5_N PF03871.9 EJS44762.1 - 6.8e-34 116.1 0.5 1.2e-33 115.3 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 EJS44762.1 - 3.4e-33 113.0 0.4 6.3e-33 112.2 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.7 EJS44762.1 - 0.019 14.7 0.0 0.091 12.5 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease DUF3249 PF11615.3 EJS44762.1 - 0.12 12.0 0.0 2.3 7.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3249) Gly_transf_sug PF04488.10 EJS44764.1 - 1.2e-20 73.8 0.1 3.6e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EJS44764.1 - 1.1 7.6 10.6 0.18 10.2 0.4 3.0 3 1 0 4 4 4 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2401 PF10287.4 EJS44765.1 - 9.7e-99 329.6 3.0 2.6e-98 328.2 2.1 1.7 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EJS44765.1 - 5.2e-30 103.3 0.9 3.2e-29 100.8 0.0 2.7 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Macoilin PF09726.4 EJS44765.1 - 0.027 12.7 14.7 0.034 12.4 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1573 PF07610.6 EJS44765.1 - 0.44 10.1 3.8 2.4 7.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1573) RAMP4 PF06624.7 EJS44766.1 - 0.0024 17.3 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Arf PF00025.16 EJS44767.1 - 7.4e-77 256.5 0.1 8.4e-77 256.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EJS44767.1 - 1.9e-11 43.5 0.0 2.3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EJS44767.1 - 2.2e-11 43.4 0.0 2.5e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EJS44767.1 - 1.5e-10 40.6 0.0 1.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EJS44767.1 - 2.8e-10 39.4 0.5 1.4e-06 27.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EJS44767.1 - 1.2e-09 38.6 0.0 1.7e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EJS44767.1 - 1.1e-05 25.0 0.2 0.00017 21.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EJS44767.1 - 0.00037 20.4 0.0 0.00055 19.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EJS44767.1 - 0.00047 20.4 0.4 0.0018 18.5 0.3 1.7 1 1 0 1 1 1 1 ABC transporter ArgK PF03308.11 EJS44767.1 - 0.0022 16.8 1.0 0.23 10.2 0.2 2.9 2 1 0 2 2 2 1 ArgK protein cobW PF02492.14 EJS44767.1 - 0.071 12.5 0.7 4.5 6.6 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EJS44767.1 - 0.14 11.6 0.4 0.55 9.6 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rpp20 PF12328.3 EJS44769.1 - 1.8e-29 102.2 4.3 1.7e-27 95.8 3.0 2.1 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EJS44769.1 - 2.1e-15 56.0 0.3 3.4e-15 55.3 0.2 1.4 1 0 0 1 1 1 1 Alba Diphthamide_syn PF01866.12 EJS44769.1 - 0.035 13.3 0.3 0.043 13.0 0.2 1.1 1 0 0 1 1 1 0 Putative diphthamide synthesis protein vWA-TerF-like PF10138.4 EJS44769.1 - 0.052 13.3 0.2 0.17 11.6 0.0 1.7 1 1 1 2 2 2 0 vWA found in TerF C terminus AA_kinase PF00696.23 EJS44769.1 - 0.054 13.0 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Amino acid kinase family Saccharop_dh_N PF04455.7 EJS44769.1 - 0.1 12.7 0.6 0.3 11.2 0.4 1.7 1 1 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region Pex24p PF06398.6 EJS44770.1 - 1.2e-59 201.9 15.2 1.4e-59 201.7 10.6 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HSP70 PF00012.15 EJS44771.1 - 3.1e-185 616.5 0.2 3.1e-185 616.5 0.1 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EJS44771.1 - 1.2e-11 43.8 0.1 3.6e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EJS44771.1 - 0.00021 21.1 4.3 0.0066 16.2 0.6 3.7 2 2 0 2 2 2 1 Cell division protein FtsA AHS1 PF02682.11 EJS44771.1 - 0.017 14.5 0.3 0.064 12.7 0.0 2.1 2 0 0 2 2 2 0 Allophanate hydrolase subunit 1 Trans_reg_C PF00486.23 EJS44771.1 - 0.068 13.0 0.0 0.29 11.0 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal FGGY_C PF02782.11 EJS44771.1 - 0.17 11.4 0.1 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain NPL4 PF05021.10 EJS44772.1 - 1.3e-127 425.2 0.1 1.7e-127 424.7 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EJS44772.1 - 1.6e-74 248.4 3.2 2.4e-74 247.8 2.2 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EJS44772.1 - 1.8e-06 28.0 0.0 6.5e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.4 EJS44773.1 - 4.5e-76 254.4 2.4 5.1e-76 254.3 1.7 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 GYF PF02213.11 EJS44774.1 - 1.9e-17 62.5 0.1 5.7e-17 61.0 0.1 1.9 1 0 0 1 1 1 1 GYF domain UMP1 PF05348.6 EJS44775.1 - 8.7e-47 158.3 0.1 1e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 WD40 PF00400.27 EJS44776.1 - 2.6e-29 100.0 13.3 4.6e-09 35.8 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EJS44776.1 - 2.2e-06 26.0 0.1 0.038 12.1 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EJS44776.1 - 8.7e-06 24.2 0.0 0.0074 14.6 0.0 2.5 2 1 1 3 3 3 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 EJS44776.1 - 0.0057 15.2 0.0 0.43 9.1 0.0 2.4 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 EJS44776.1 - 0.13 11.9 0.0 6.9 6.4 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.15 EJS44777.1 - 3.2e-39 134.8 0.0 4.9e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EJS44777.1 - 2.5e-15 57.0 0.0 3.4e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EJS44777.1 - 1.2e-10 41.3 0.0 5.6e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EJS44777.1 - 0.00052 19.2 0.0 0.024 13.8 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family ORC3_N PF07034.6 EJS44777.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Dynamin_N PF00350.18 EJS44778.1 - 4.8e-14 52.5 0.3 4.8e-14 52.5 0.2 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EJS44778.1 - 2.3e-08 33.9 0.8 1.4e-07 31.4 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EJS44778.1 - 2.6e-07 30.2 3.0 5.3e-06 25.9 1.9 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EJS44778.1 - 0.016 14.6 0.1 8.3 5.8 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TTL PF03133.10 EJS44779.1 - 4.5e-95 317.9 4.6 6.3e-95 317.4 3.2 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EJS44779.1 - 4.6e-38 130.5 0.0 8.4e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 EJS44779.1 - 0.0009 19.0 0.0 0.0026 17.5 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Nro1 PF12753.2 EJS44779.1 - 0.0025 16.8 3.6 0.0055 15.7 2.5 1.5 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 ATPgrasp_YheCD PF14398.1 EJS44779.1 - 0.012 14.4 0.0 0.092 11.5 0.0 2.3 2 0 0 2 2 2 0 YheC/D like ATP-grasp Sedlin_N PF04628.8 EJS44779.1 - 0.014 15.3 0.7 2.2 8.1 0.2 2.5 2 0 0 2 2 2 0 Sedlin, N-terminal conserved region RXT2_N PF08595.6 EJS44780.1 - 7.9e-45 152.3 0.6 7.9e-45 152.3 0.4 2.9 3 0 0 3 3 3 1 RXT2-like, N-terminal 4HBT_2 PF13279.1 EJS44781.1 - 4.2e-08 33.6 0.0 6.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.20 EJS44782.1 - 1.9e-26 92.7 0.0 7.1e-26 90.9 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44782.1 - 2e-13 50.0 0.0 3.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 EJS44782.1 - 9.8e-09 34.5 2.7 2.5 8.4 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EJS44782.1 - 1.6e-05 25.0 0.1 0.001 19.2 0.0 3.1 2 1 1 3 3 3 1 HEAT repeats Kinase-like PF14531.1 EJS44782.1 - 0.072 12.0 1.0 0.71 8.7 0.0 2.5 2 1 0 2 2 2 0 Kinase-like WD40 PF00400.27 EJS44782.1 - 0.82 9.6 0.0 0.82 9.6 0.0 4.3 5 0 0 5 5 5 0 WD domain, G-beta repeat ERCC4 PF02732.10 EJS44783.1 - 1.3e-06 28.2 2.9 1.3e-06 28.2 2.0 2.2 1 1 1 2 2 2 1 ERCC4 domain H-kinase_dim PF02895.9 EJS44783.1 - 0.011 16.0 0.1 17 5.8 0.0 3.8 3 2 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Fes1 PF08609.5 EJS44784.1 - 4e-28 97.7 0.6 1.3e-27 96.1 0.2 2.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EJS44784.1 - 7.5e-06 26.1 0.2 0.00016 21.8 0.0 2.8 2 1 1 3 3 3 1 HEAT repeats IBN_N PF03810.14 EJS44784.1 - 0.00028 20.7 0.8 0.36 10.7 0.1 3.4 2 1 2 4 4 4 2 Importin-beta N-terminal domain UPF0253 PF06786.7 EJS44784.1 - 0.024 14.7 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) HEAT_EZ PF13513.1 EJS44784.1 - 0.055 13.9 0.2 0.47 11.0 0.1 2.7 2 1 1 3 3 3 0 HEAT-like repeat V-ATPase_H_C PF11698.3 EJS44784.1 - 0.075 12.9 0.5 0.23 11.3 0.2 1.9 2 0 0 2 2 2 0 V-ATPase subunit H Vps51 PF08700.6 EJS44785.1 - 7.7e-08 32.0 1.8 7.7e-08 32.0 1.3 2.5 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.6 EJS44785.1 - 0.0061 16.4 3.2 0.0061 16.4 2.2 3.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 WD40 PF00400.27 EJS44786.1 - 1.6e-27 94.3 13.2 1.1e-08 34.6 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat LisH PF08513.6 EJS44786.1 - 8.4e-07 28.5 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 LisH RAB3GAP2_N PF14655.1 EJS44786.1 - 0.0013 17.7 0.1 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.3 EJS44786.1 - 0.0071 14.5 2.8 0.26 9.3 0.0 3.1 3 1 0 4 4 4 2 Nucleoporin Nup120/160 DUF4099 PF13351.1 EJS44786.1 - 0.024 14.5 0.0 0.53 10.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4099) Mito_carr PF00153.22 EJS44787.1 - 1.8e-61 203.8 1.2 4.8e-22 77.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Vac_ImportDeg PF09783.4 EJS44788.1 - 2.2e-69 232.5 3.9 5.7e-69 231.1 2.7 1.6 1 1 0 1 1 1 1 Vacuolar import and degradation protein Pho88 PF10032.4 EJS44789.1 - 2.3e-83 278.1 0.9 2.5e-83 278.0 0.7 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) CENP-L PF13092.1 EJS44790.1 - 0.00019 21.2 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 EF-hand_1 PF00036.27 EJS44791.1 - 2.3e-30 101.5 4.3 1.7e-08 33.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EJS44791.1 - 9.3e-27 92.9 0.8 2.1e-13 50.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EJS44791.1 - 4.8e-26 88.2 3.1 6.3e-08 31.8 0.0 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EJS44791.1 - 9e-18 63.6 5.7 9.1e-07 28.4 0.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EJS44791.1 - 3e-17 61.0 3.7 1.9e-07 30.1 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EJS44791.1 - 2e-12 46.8 0.0 1.5e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EJS44791.1 - 1.8e-06 27.9 0.2 0.00058 19.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EJS44791.1 - 3.5e-06 26.5 0.0 0.018 14.6 0.0 2.7 2 1 0 3 3 3 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 EJS44791.1 - 0.00077 19.0 0.0 0.39 10.2 0.0 2.2 2 0 0 2 2 2 2 Caleosin related protein EF-hand_4 PF12763.2 EJS44791.1 - 0.0025 17.5 0.5 0.0069 16.1 0.1 1.7 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.7 EJS44791.1 - 0.0035 15.7 0.3 0.093 11.0 0.0 2.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) TerB PF05099.8 EJS44791.1 - 0.009 15.7 0.1 0.44 10.2 0.0 2.2 2 1 0 2 2 2 1 Tellurite resistance protein TerB PepSY_2 PF13670.1 EJS44791.1 - 0.068 13.0 0.0 9 6.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain RNA_pol_Rpb4 PF03874.11 EJS44791.1 - 0.15 12.0 0.6 1.8 8.5 0.0 2.4 2 1 0 2 2 2 0 RNA polymerase Rpb4 Glycos_transf_1 PF00534.15 EJS44792.1 - 6.7e-13 48.4 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EJS44792.1 - 1.8e-12 47.5 0.0 5.9e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EJS44792.1 - 2.8e-05 24.2 0.0 5.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EJS44792.1 - 0.00039 20.5 0.0 0.00056 20.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain SNF2_N PF00176.18 EJS44793.1 - 8e-76 254.6 0.2 1.2e-75 254.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EJS44793.1 - 5.3e-10 39.0 0.0 1.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EJS44793.1 - 3.3e-09 36.4 0.0 6.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EJS44793.1 - 5.9e-08 32.2 11.3 5.9e-08 32.2 7.8 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EJS44793.1 - 5.9e-05 22.8 9.1 5.9e-05 22.8 6.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EJS44793.1 - 0.00023 21.1 9.4 0.00023 21.1 6.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EJS44793.1 - 0.003 17.4 9.7 0.003 17.4 6.7 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EJS44793.1 - 0.31 10.8 3.3 0.93 9.3 2.3 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.1 EJS44793.1 - 2.7 7.5 12.9 0.52 9.8 1.6 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain AMP-binding PF00501.23 EJS44794.1 - 1.7e-71 240.8 0.0 2.3e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EJS44794.1 - 7.7e-69 231.3 0.0 1.3e-68 230.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EJS44794.1 - 1.9e-15 56.8 0.0 4e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EJS44794.1 - 1.3e-11 44.4 0.0 2.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EJS44794.1 - 1.6e-07 32.1 0.1 6.8e-07 30.1 0.0 2.2 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EJS44794.1 - 5.1e-05 22.1 0.0 0.00019 20.2 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Transketolase_N PF00456.16 EJS44795.1 - 1.7e-152 507.0 0.0 2.2e-152 506.6 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EJS44795.1 - 3.6e-48 163.3 0.0 5.9e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EJS44795.1 - 6.6e-13 48.6 0.0 1.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EJS44795.1 - 4.3e-06 25.8 0.0 8.5e-05 21.6 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EJS44795.1 - 0.0009 18.8 0.2 0.11 12.0 0.1 2.5 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EJS44795.1 - 0.0035 16.1 0.0 0.0094 14.7 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component FtsJ PF01728.14 EJS44796.1 - 3.7e-63 212.7 0.0 4.6e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF268 PF03269.9 EJS44796.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 DUF1631 PF07793.6 EJS44797.1 - 0.023 12.8 0.0 0.037 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) zf-H2C2_2 PF13465.1 EJS44798.1 - 8.8e-06 25.7 2.3 8.8e-06 25.7 1.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EJS44798.1 - 1.4e-05 25.0 13.5 0.0063 16.7 4.1 3.1 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EJS44798.1 - 0.00047 20.3 19.2 0.02 15.2 2.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-RING-like PF08746.6 EJS44798.1 - 0.17 11.8 4.2 0.47 10.5 2.9 1.7 1 0 0 1 1 1 0 RING-like domain zf-met PF12874.2 EJS44798.1 - 1.4 9.2 8.4 0.21 11.8 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type AA_permease PF00324.16 EJS44799.1 - 2.8e-135 451.3 37.6 3.4e-135 451.0 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS44799.1 - 1.3e-33 116.2 37.7 1.7e-33 115.7 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease Synaptobrevin PF00957.16 EJS44799.1 - 0.33 10.5 0.0 0.33 10.5 0.0 3.4 4 0 0 4 4 4 0 Synaptobrevin AA_permease PF00324.16 EJS44800.1 - 1.6e-125 419.1 38.7 1.8e-125 418.9 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EJS44800.1 - 1.2e-39 136.0 38.1 1.4e-39 135.8 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 EJS44800.1 - 0.0014 17.3 16.6 0.0014 17.3 11.5 3.1 2 2 0 3 3 3 1 Spore germination protein ROK PF00480.15 EJS44800.1 - 0.049 13.4 1.7 0.083 12.7 0.8 1.6 1 1 0 1 1 1 0 ROK family DUF2207 PF09972.4 EJS44800.1 - 1.6 7.2 0.0 1.6 7.2 0.0 3.6 4 1 1 5 5 5 0 Predicted membrane protein (DUF2207) Alg14 PF08660.6 EJS44801.1 - 4.2e-51 173.3 0.1 5.8e-51 172.8 0.1 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like CTF_NFI PF00859.13 EJS44802.1 - 0.55 9.9 10.1 0.85 9.3 7.0 1.4 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region Sorting_nexin PF03700.8 EJS44802.1 - 2.1 8.4 8.0 1.2 9.2 0.2 2.4 1 1 1 2 2 2 0 Sorting nexin, N-terminal domain HSP20 PF00011.16 EJS44803.1 - 5.4e-25 87.2 3.0 7.1e-25 86.8 2.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Peptidase_M28 PF04389.12 EJS44804.1 - 3.1e-32 111.7 0.0 5.7e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EJS44804.1 - 5.1e-06 26.1 0.0 6.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EJS44804.1 - 0.0025 16.6 0.0 0.015 14.0 0.0 1.9 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase DUF3091 PF11291.3 EJS44805.1 - 0.35 10.8 2.9 0.7 9.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) PCI PF01399.22 EJS44806.1 - 2.7e-06 27.6 7.5 3.7e-06 27.1 0.2 3.9 3 1 1 4 4 4 1 PCI domain AAA PF00004.24 EJS44807.1 - 2e-51 173.6 0.0 1.6e-38 131.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EJS44807.1 - 1.1e-15 57.3 0.0 4.9e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 EJS44807.1 - 1.4e-09 38.1 1.0 0.00088 19.4 0.2 3.5 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EJS44807.1 - 4.2e-09 35.9 0.8 1.4e-08 34.2 0.1 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 EJS44807.1 - 6.1e-09 36.7 0.0 0.0039 18.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EJS44807.1 - 2.8e-08 33.3 0.2 0.0041 16.8 0.1 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 EJS44807.1 - 2.9e-08 33.8 0.0 0.0076 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 EJS44807.1 - 4.2e-07 29.7 0.3 0.0016 18.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EJS44807.1 - 8.4e-07 28.0 0.1 0.027 13.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 EJS44807.1 - 1.4e-06 27.6 0.2 0.0017 17.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EJS44807.1 - 2.7e-06 27.3 0.0 0.028 14.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EJS44807.1 - 2.9e-06 27.6 0.2 0.021 15.1 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_14 PF13173.1 EJS44807.1 - 1.2e-05 25.2 0.0 0.05 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EJS44807.1 - 1.8e-05 24.2 0.2 0.05 13.0 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EJS44807.1 - 1.9e-05 24.8 0.1 0.11 12.7 0.0 3.3 3 0 0 3 3 3 2 RNA helicase PhoH PF02562.11 EJS44807.1 - 2e-05 23.9 0.0 0.027 13.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.7 EJS44807.1 - 3.3e-05 23.6 4.1 0.021 14.4 0.1 3.7 4 1 0 5 5 4 1 NACHT domain AAA_2 PF07724.9 EJS44807.1 - 3.4e-05 23.8 0.0 0.0013 18.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EJS44807.1 - 5.3e-05 22.3 0.6 0.071 12.1 0.1 2.9 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 EJS44807.1 - 9.1e-05 21.5 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EJS44807.1 - 0.00014 20.8 0.0 0.12 11.2 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.22 EJS44807.1 - 0.00025 21.3 0.7 0.029 14.6 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 EJS44807.1 - 0.00032 20.2 0.0 0.79 9.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 EJS44807.1 - 0.001 18.7 2.6 0.45 10.0 0.3 2.7 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EJS44807.1 - 0.0015 17.6 0.0 0.92 8.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 EJS44807.1 - 0.0016 18.2 0.8 1.9 8.1 0.0 3.2 2 1 1 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 EJS44807.1 - 0.0016 17.8 5.7 1.6 8.1 0.1 4.0 2 2 1 4 4 4 2 AAA domain KaiC PF06745.8 EJS44807.1 - 0.0019 17.3 0.4 0.23 10.5 0.1 2.6 2 0 0 2 2 2 1 KaiC ResIII PF04851.10 EJS44807.1 - 0.0024 17.7 0.0 0.99 9.2 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UPF0079 PF02367.12 EJS44807.1 - 0.0031 17.1 0.1 2.4 7.7 0.0 3.0 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EJS44807.1 - 0.0033 16.8 0.1 0.08 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_11 PF13086.1 EJS44807.1 - 0.0062 16.1 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EJS44807.1 - 0.0063 16.1 0.0 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EJS44807.1 - 0.0071 15.8 0.1 31 4.0 0.0 3.9 3 1 1 4 4 4 0 DEAD/DEAH box helicase AAA_23 PF13476.1 EJS44807.1 - 0.013 15.7 1.5 3.8 7.7 0.1 3.1 3 1 0 3 3 3 0 AAA domain IPT PF01745.11 EJS44807.1 - 0.014 14.5 0.1 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase AAA_28 PF13521.1 EJS44807.1 - 0.017 15.0 0.0 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EJS44807.1 - 0.025 14.2 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EJS44807.1 - 0.026 13.4 0.0 4.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EJS44807.1 - 0.029 14.3 0.4 16 5.5 0.0 3.2 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EJS44807.1 - 0.031 13.1 0.0 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 EJS44807.1 - 0.042 13.4 0.0 11 5.6 0.0 2.9 3 0 0 3 3 3 0 Bacterial dnaA protein Zot PF05707.7 EJS44807.1 - 0.15 11.5 0.2 20 4.5 0.0 2.9 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) TEA PF01285.13 EJS44808.1 - 2e-80 271.0 12.0 2.4e-80 270.8 8.3 1.1 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-bind_3 PF12776.2 EJS44808.1 - 1.2 9.8 5.4 1.3 9.7 1.2 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain FTHFS PF01268.14 EJS44809.1 - 7.7e-257 852.7 1.3 1.1e-256 852.2 0.9 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EJS44809.1 - 1.6e-70 235.3 0.5 1.6e-70 235.3 0.4 2.6 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EJS44809.1 - 1.4e-36 125.0 1.6 3.4e-36 123.8 0.6 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Mito_carr PF00153.22 EJS44810.1 - 1.4e-69 229.8 7.6 3.1e-24 84.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4421 PF14391.1 EJS44811.1 - 0.052 12.7 0.2 0.054 12.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4421) Anoctamin PF04547.7 EJS44812.1 - 2.1e-43 148.6 32.5 9.6e-43 146.4 22.5 2.1 1 1 0 1 1 1 1 Calcium-activated chloride channel Dehydrin PF00257.14 EJS44812.1 - 1.9 8.8 20.4 0.074 13.3 9.8 1.8 2 0 0 2 2 2 0 Dehydrin Rep_fac_C PF08542.6 EJS44813.1 - 9.8e-19 67.1 1.1 1.1e-17 63.7 0.2 2.5 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EJS44813.1 - 6.7e-12 45.3 0.2 1.9e-11 43.8 0.1 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EJS44813.1 - 1.3e-08 35.0 0.1 4.1e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EJS44813.1 - 0.0014 18.7 1.3 0.0082 16.2 0.2 2.7 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EJS44813.1 - 0.002 18.1 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EJS44813.1 - 0.0031 17.5 0.1 0.39 10.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 EJS44813.1 - 0.029 13.4 0.0 0.097 11.7 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EJS44813.1 - 0.065 12.9 0.2 0.27 10.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PCNA_C PF02747.10 EJS44814.1 - 3.7e-52 175.5 0.0 9.1e-52 174.3 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 EJS44814.1 - 8.7e-52 173.9 1.2 8.7e-52 173.9 0.8 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.11 EJS44814.1 - 0.00015 20.6 0.6 0.0031 16.3 0.4 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EJS44814.1 - 0.00019 20.6 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Rad9 HMG_box PF00505.14 EJS44815.1 - 5.4e-24 84.2 0.2 8.5e-24 83.6 0.1 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EJS44815.1 - 4e-18 65.5 0.2 6.2e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EJS44815.1 - 0.00055 19.6 0.4 0.00055 19.6 0.2 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box 5 Methyltransf_31 PF13847.1 EJS44816.1 - 7.5e-13 48.3 0.0 1.3e-12 47.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EJS44816.1 - 3.2e-12 46.1 0.0 1e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EJS44816.1 - 1e-10 41.6 0.0 2.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EJS44816.1 - 4.2e-10 40.1 0.0 1.6e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EJS44816.1 - 1.2e-07 32.1 0.0 3e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EJS44816.1 - 6.3e-07 29.2 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EJS44816.1 - 1.4e-06 27.7 0.0 2.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EJS44816.1 - 1.7e-06 28.3 0.0 4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EJS44816.1 - 4.7e-06 25.8 0.0 5.7e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 EJS44816.1 - 7.9e-06 24.7 0.1 1.1e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EJS44816.1 - 3.7e-05 22.9 0.0 5.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EJS44816.1 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EJS44816.1 - 0.00022 21.6 0.0 0.0006 20.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.14 EJS44816.1 - 0.00066 19.7 0.0 0.0028 17.6 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.11 EJS44816.1 - 0.0045 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 EJS44816.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 EJS44816.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EJS44816.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EJS44816.1 - 0.057 12.4 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 EJS44816.1 - 0.068 12.4 0.2 0.16 11.2 0.1 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 Cons_hypoth95 PF03602.10 EJS44816.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PNPOx_C PF10590.4 EJS44817.1 - 3.3e-21 74.4 2.8 7.2e-21 73.4 1.9 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EJS44817.1 - 4e-14 52.3 0.0 6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EJS44817.1 - 0.0086 16.3 0.1 0.015 15.6 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Chitin_synth_1 PF01644.12 EJS44819.1 - 1.8e-78 261.9 0.5 2.8e-78 261.3 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EJS44819.1 - 4.8e-26 90.2 0.0 1.3e-25 88.8 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EJS44819.1 - 5.9e-25 87.6 3.3 3.1e-19 68.7 0.0 3.0 2 1 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EJS44819.1 - 2e-11 44.1 0.0 6.4e-10 39.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EJS44819.1 - 9.9e-10 38.4 0.9 9.9e-10 38.4 0.6 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Ant_C PF05586.6 EJS44819.1 - 0.13 12.7 0.6 0.97 9.9 0.4 2.3 1 1 0 1 1 1 0 Anthrax receptor C-terminus region ATP-synt PF00231.14 EJS44820.1 - 3.1e-67 226.9 5.0 3.6e-67 226.7 3.5 1.0 1 0 0 1 1 1 1 ATP synthase MecA_N PF05223.6 EJS44820.1 - 0.015 15.3 3.8 0.034 14.2 2.7 1.6 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain Fig1 PF12351.3 EJS44821.1 - 2.8e-57 193.5 5.9 2.8e-57 193.5 4.1 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EJS44821.1 - 5.2e-05 22.9 14.3 8.3e-05 22.2 9.9 1.3 1 0 0 1 1 1 1 SUR7/PalI family AMP-binding PF00501.23 EJS44822.1 - 2e-65 220.8 0.0 2.4e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ADH_zinc_N PF00107.21 EJS44823.1 - 8.9e-28 96.4 0.0 1.4e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EJS44823.1 - 1.3e-11 45.5 0.0 4.7e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EJS44823.1 - 5.5e-10 38.9 0.0 1.7e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Flavodoxin_1 PF00258.20 EJS44825.1 - 0.001 19.1 0.2 0.0026 17.7 0.2 1.7 1 1 0 1 1 1 1 Flavodoxin DUF2403 PF10290.4 EJS44825.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycine-rich protein domain (DUF2403) SGL PF08450.7 EJS44826.1 - 1.5e-48 165.3 0.0 2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EJS44826.1 - 0.00028 20.8 0.0 0.71 9.9 0.0 2.4 2 0 0 2 2 2 2 Arylesterase Bac_rhodopsin PF01036.13 EJS44827.1 - 1.6e-40 138.8 18.6 2.1e-40 138.3 12.9 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein SR-25 PF10500.4 EJS44827.1 - 0.44 9.9 19.4 0.58 9.5 13.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GpcrRhopsn4 PF10192.4 EJS44827.1 - 0.76 8.9 18.1 0.22 10.6 5.3 2.2 1 1 1 2 2 2 0 Rhodopsin-like GPCR transmembrane domain Med19 PF10278.4 EJS44827.1 - 1.4 8.6 14.9 2.1 8.0 10.3 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4316 PF14195.1 EJS44827.1 - 1.9 8.5 10.0 3.6 7.7 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) BLVR PF06375.6 EJS44827.1 - 2.1 8.1 14.6 2.9 7.7 10.1 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Prefoldin_2 PF01920.15 EJS44830.1 - 0.024 14.3 2.8 0.024 14.3 1.9 3.5 3 1 0 3 3 3 0 Prefoldin subunit EMP24_GP25L PF01105.19 EJS44830.1 - 2.4 7.8 8.5 0.2 11.3 1.1 2.5 2 1 0 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF641 PF04859.7 EJS44830.1 - 3.2 7.5 16.7 0.095 12.4 0.5 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) UCH PF00443.24 EJS44831.1 - 9.2e-49 165.9 0.0 2.6e-48 164.4 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EJS44831.1 - 3e-26 92.5 0.2 1.9e-25 89.9 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EJS44831.1 - 8.6e-19 67.4 9.0 8.6e-19 67.4 6.2 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EJS44831.1 - 8.5e-16 57.2 0.0 9e-07 28.5 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain Cytochrom_B558a PF05038.8 EJS44832.1 - 0.079 12.5 0.2 0.09 12.4 0.2 1.1 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Pkinase PF00069.20 EJS44833.1 - 1.5e-34 119.3 0.1 3.2e-34 118.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44833.1 - 1.1e-23 83.6 0.0 1.1e-23 83.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EJS44833.1 - 0.045 13.4 0.0 0.85 9.3 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family UPF0029 PF01205.14 EJS44833.1 - 0.065 12.9 1.7 0.16 11.6 1.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 ORC2 PF04084.9 EJS44834.1 - 8.8e-113 376.4 2.8 1.3e-112 375.8 2.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.14 EJS44834.1 - 0.08 12.6 3.8 0.29 10.9 2.6 2.1 1 0 0 1 1 1 0 AT hook motif adh_short_C2 PF13561.1 EJS44835.1 - 2.7e-14 53.5 0.0 3.5e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EJS44835.1 - 3.4e-12 46.6 0.0 4.6e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EJS44835.1 - 4.7e-07 29.6 0.0 7.5e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EJS44835.1 - 0.019 14.4 0.2 0.037 13.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ENT PF03735.9 EJS44835.1 - 0.041 13.5 0.5 11 5.8 0.0 2.4 2 0 0 2 2 2 0 ENT domain Carn_acyltransf PF00755.15 EJS44836.1 - 1.3e-206 687.2 0.0 1.5e-206 687.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Oxysterol_BP PF01237.13 EJS44837.1 - 3.7e-129 430.2 0.0 3.7e-129 430.2 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EJS44837.1 - 9e-13 48.3 0.1 4.1e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EJS44837.1 - 2.1e-11 43.6 0.2 0.00011 22.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EJS44837.1 - 4.8e-11 41.8 0.0 0.00099 18.8 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EJS44837.1 - 6.3e-11 42.4 0.0 0.00019 21.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EJS44837.1 - 2.1e-08 33.6 0.1 0.017 15.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat PH PF00169.24 EJS44837.1 - 1.3e-07 31.7 0.6 3.5e-07 30.3 0.1 2.1 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 EJS44837.1 - 1.3e-07 31.5 1.0 2.9e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 EJS44837.1 - 9.8e-06 25.7 0.4 9.8e-06 25.7 0.3 3.0 4 0 0 4 4 4 1 Pleckstrin homology domain LMBR1 PF04791.11 EJS44837.1 - 6.1 5.3 4.4 8.8 4.7 3.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Kelch_4 PF13418.1 EJS44838.1 - 5e-13 48.5 2.3 1.9e-05 24.3 0.0 4.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EJS44838.1 - 5.6e-10 39.1 0.7 0.00023 21.2 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EJS44838.1 - 9.6e-09 34.6 4.0 0.036 13.6 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 EJS44838.1 - 1.3e-08 34.5 5.7 0.0046 16.8 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 EJS44838.1 - 3.3e-06 27.0 3.5 0.16 12.2 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EJS44838.1 - 4.8e-06 26.1 8.1 0.079 12.7 0.0 5.8 7 0 0 7 7 7 2 Kelch motif Peroxin-22 PF12827.2 EJS44839.1 - 1.8e-24 85.7 0.0 2.2e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family AMP-binding PF00501.23 EJS44840.1 - 1.4e-90 303.7 0.1 1.7e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EJS44840.1 - 3.6e-20 72.6 0.0 1.1e-18 67.9 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GNAT_acetyltran PF12746.2 EJS44840.1 - 0.1 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase TRP PF06011.7 EJS44841.1 - 1.3e-156 521.5 36.9 1.9e-156 521.0 25.6 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EJS44841.1 - 1.5e-44 151.4 1.4 2.7e-44 150.6 1.0 1.4 1 0 0 1 1 1 1 ML-like domain Neur_chan_memb PF02932.11 EJS44841.1 - 0.0059 16.5 0.1 0.0059 16.5 0.0 2.7 3 0 0 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region DUF4154 PF13689.1 EJS44841.1 - 0.0071 15.9 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4154) Zn_clus PF00172.13 EJS44842.1 - 7e-12 45.0 10.5 1.3e-11 44.2 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Miro PF08477.8 EJS44843.1 - 4.7e-50 169.0 0.0 1.8e-24 86.5 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EJS44843.1 - 4.6e-29 100.0 0.1 1.7e-28 98.1 0.0 2.0 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.7 EJS44843.1 - 1.1e-27 95.0 1.3 2.4e-27 93.9 0.9 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EJS44843.1 - 3.4e-25 88.3 0.0 1.5e-13 50.4 0.0 3.0 2 1 0 2 2 2 2 Ras family EF-hand_7 PF13499.1 EJS44843.1 - 5.3e-07 29.6 2.6 0.0054 16.8 0.0 3.3 3 0 0 3 3 2 2 EF-hand domain pair MMR_HSR1 PF01926.18 EJS44843.1 - 5.7e-07 29.4 0.0 0.0047 16.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 EJS44843.1 - 6.8e-06 25.0 1.8 0.0036 16.5 0.3 3.3 2 0 0 2 2 2 1 EF hand Dynamin_N PF00350.18 EJS44843.1 - 7.4e-05 22.6 0.1 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 Dynamin family Arf PF00025.16 EJS44843.1 - 0.00019 20.6 0.0 0.0045 16.2 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.1 EJS44843.1 - 0.0013 18.7 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EJS44843.1 - 0.0022 17.2 0.1 0.074 12.2 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EJS44843.1 - 0.0032 17.7 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 EJS44843.1 - 0.0039 16.8 0.0 0.042 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.1 EJS44843.1 - 0.0045 16.2 0.9 0.027 13.8 0.6 2.5 1 0 0 1 1 1 1 EF hand AAA_28 PF13521.1 EJS44843.1 - 0.0053 16.7 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EJS44843.1 - 0.0058 16.1 0.0 2.7 7.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_6 PF13405.1 EJS44843.1 - 0.012 15.4 6.0 0.059 13.2 0.2 3.6 3 0 0 3 3 3 0 EF-hand domain AAA_33 PF13671.1 EJS44843.1 - 0.015 15.1 0.0 4.9 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.13 EJS44843.1 - 0.042 13.1 0.0 5.5 6.2 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_22 PF13401.1 EJS44843.1 - 0.044 13.9 0.0 3.1 7.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 EJS44843.1 - 0.046 12.6 0.0 2.7 6.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Septin PF00735.13 EJS44843.1 - 0.055 12.4 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Septin EF-hand_8 PF13833.1 EJS44843.1 - 0.058 13.0 1.4 0.28 10.8 0.2 2.5 2 0 0 2 2 2 0 EF-hand domain pair AAA_18 PF13238.1 EJS44843.1 - 0.061 13.6 0.0 19 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EJS44843.1 - 0.1 13.4 0.0 15 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain MCM PF00493.18 EJS44843.1 - 0.11 11.2 0.0 6.1 5.5 0.0 2.2 2 0 0 2 2 2 0 MCM2/3/5 family Arch_ATPase PF01637.13 EJS44843.1 - 0.11 12.1 0.2 7.5 6.1 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 EJS44843.1 - 0.11 12.6 0.0 5 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase BolA PF01722.13 EJS44844.1 - 2.1e-24 85.2 0.0 2.6e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein GCV_H PF01597.14 EJS44845.1 - 3.9e-48 162.1 1.1 4.8e-48 161.8 0.7 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EJS44845.1 - 8.7e-05 22.0 1.4 0.00027 20.5 0.2 2.0 1 1 1 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 EJS44845.1 - 0.07 12.8 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF3453 PF11935.3 EJS44846.1 - 1.1e-68 231.1 1.8 3.2e-68 229.7 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Mpp10 PF04006.7 EJS44846.1 - 0.0098 14.3 11.2 0.013 13.8 7.7 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF2201_N PF13203.1 EJS44846.1 - 0.06 12.5 5.2 0.1 11.7 3.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Sigma70_ner PF04546.8 EJS44846.1 - 0.13 11.8 9.7 0.26 10.8 6.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 EJS44846.1 - 0.36 9.2 17.4 0.58 8.5 12.0 1.2 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 EJS44846.1 - 0.8 9.1 7.3 1.5 8.2 5.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO COPIIcoated_ERV PF07970.7 EJS44847.1 - 3.9e-69 232.6 0.1 4.8e-69 232.3 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EJS44847.1 - 2.7e-32 110.5 0.6 4.8e-32 109.8 0.1 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DnaJ_CXXCXGXG PF00684.14 EJS44847.1 - 2.1 8.4 8.5 0.24 11.4 2.7 1.7 2 0 0 2 2 2 0 DnaJ central domain RhoGEF PF00621.15 EJS44848.1 - 4.3e-37 127.7 6.1 4.3e-37 127.7 4.3 3.0 2 1 0 2 2 2 1 RhoGEF domain CDC24 PF06395.6 EJS44848.1 - 5.4e-36 122.5 1.0 9.7e-35 118.4 0.4 2.7 2 0 0 2 2 2 1 CDC24 Calponin PH_10 PF15411.1 EJS44848.1 - 1.3e-18 67.3 12.6 2.2e-09 37.5 0.4 3.8 2 1 0 3 3 3 2 Pleckstrin homology domain PB1 PF00564.19 EJS44848.1 - 1.6e-05 24.4 0.0 6.2e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 PB1 domain Cyclin_N PF00134.18 EJS44849.1 - 5.2e-24 84.2 2.3 9e-24 83.4 1.6 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain RAMP PF04901.8 EJS44849.1 - 0.0053 16.4 0.7 0.44 10.3 0.1 2.7 2 0 0 2 2 2 2 Receptor activity modifying family PK PF00224.16 EJS44850.1 - 5.2e-167 554.7 1.6 6.4e-167 554.4 1.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EJS44850.1 - 3e-28 97.7 0.1 8.6e-28 96.2 0.0 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EJS44850.1 - 9.2e-06 24.7 0.3 2.2e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family TGS PF02824.16 EJS44851.1 - 2.6e-21 75.1 0.1 4.8e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EJS44851.1 - 4.9e-17 61.9 0.0 9.6e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EJS44851.1 - 4e-10 39.1 0.0 1.2e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EJS44851.1 - 0.0022 17.8 0.4 1.9 8.2 0.0 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EJS44851.1 - 0.0078 15.6 0.0 11 5.3 0.0 3.6 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EJS44851.1 - 0.0086 14.8 0.2 0.015 14.0 0.1 1.3 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 EJS44851.1 - 0.021 15.2 0.0 0.045 14.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 EJS44851.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EJS44852.1 - 5.6e-31 107.4 0.0 5.6e-31 107.4 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EJS44852.1 - 5.4e-22 77.7 0.0 1.5e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EJS44852.1 - 1.8e-15 56.7 1.4 6.4e-10 39.0 0.0 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EJS44852.1 - 1.2e-06 28.5 0.1 7.8e-06 25.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EJS44852.1 - 0.0011 18.5 0.0 0.0076 15.8 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU_D4 PF14578.1 EJS44852.1 - 0.02 14.5 0.1 0.056 13.0 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 AAA_22 PF13401.1 EJS44852.1 - 0.032 14.3 0.1 0.17 12.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain Mis12 PF05859.7 EJS44853.1 - 2.9e-47 160.0 3.2 2.9e-47 160.0 2.2 2.0 3 0 0 3 3 3 1 Mis12 protein RRF_GI PF12614.3 EJS44853.1 - 0.046 13.5 8.0 0.16 11.7 1.9 2.7 2 1 1 3 3 3 0 Ribosome recycling factor Spectrin PF00435.16 EJS44853.1 - 0.14 12.4 5.8 7.3 6.9 1.9 2.5 2 0 0 2 2 2 0 Spectrin repeat BLOC1_2 PF10046.4 EJS44853.1 - 1 9.5 11.8 0.34 11.0 4.2 3.0 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SWIRM PF04433.12 EJS44854.1 - 1.4e-13 50.7 0.0 2.7e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain NT-C2 PF10358.4 EJS44854.1 - 0.006 16.0 0.1 0.031 13.7 0.0 2.0 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins LLC1 PF14945.1 EJS44855.1 - 0.091 13.0 1.5 0.15 12.3 0.1 2.1 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein HAD PF12710.2 EJS44856.1 - 5.6e-20 72.3 0.2 1.6e-19 70.8 0.1 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EJS44856.1 - 3.3e-18 65.5 0.7 6.1e-18 64.6 0.5 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EJS44856.1 - 5.3e-14 53.1 1.1 2.8e-11 44.2 0.3 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EJS44856.1 - 5.9e-10 38.9 0.0 1.5e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EJS44856.1 - 0.001 18.7 0.5 0.01 15.4 0.4 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EJS44856.1 - 0.019 15.2 0.1 0.044 13.9 0.1 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Mak16 PF04874.9 EJS44857.1 - 7.2e-37 125.5 15.0 7.2e-37 125.5 10.4 2.7 2 1 0 2 2 2 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.12 EJS44857.1 - 1.2e-32 112.7 1.9 1.2e-32 112.7 1.3 2.0 3 0 0 3 3 3 1 Ribosomal L28e protein family Nop14 PF04147.7 EJS44857.1 - 2.9 5.7 26.7 3.7 5.3 18.5 1.2 1 0 0 1 1 1 0 Nop14-like family RasGEF PF00617.14 EJS44858.1 - 8.8e-43 146.2 1.3 3.2e-42 144.3 0.9 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EJS44858.1 - 2.6e-13 49.9 7.1 3.7e-12 46.2 0.1 3.8 3 0 0 3 3 3 2 RasGEF N-terminal motif Erythro_esteras PF05139.9 EJS44858.1 - 0.068 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Erythromycin esterase PMT PF02366.13 EJS44859.1 - 3.8e-94 314.6 23.2 3.8e-94 314.6 16.1 2.9 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EJS44859.1 - 1.7e-29 102.7 0.2 3.6e-29 101.6 0.2 1.5 1 0 0 1 1 1 1 MIR domain Nucleoside_tran PF01733.13 EJS44860.1 - 3.5e-95 318.7 7.0 3.5e-95 318.7 4.9 1.6 2 0 0 2 2 2 1 Nucleoside transporter Exo_endo_phos PF03372.18 EJS44861.1 - 4.2e-25 89.1 1.0 7.2e-25 88.3 0.7 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EJS44861.1 - 9.1e-15 53.8 4.8 3.4e-10 39.2 2.1 3.8 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EJS44861.1 - 1.5e-10 39.5 13.7 0.00077 19.1 0.1 6.4 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_8 PF13855.1 EJS44861.1 - 7.6e-10 38.4 6.9 1.8e-09 37.2 1.3 3.2 1 1 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 EJS44861.1 - 7.1e-08 31.4 10.7 0.0043 17.0 0.4 5.7 5 0 0 5 5 5 2 Leucine rich repeat RCC1 PF00415.13 EJS44862.1 - 1.2e-23 83.0 18.1 6e-13 48.7 0.2 4.9 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EJS44862.1 - 8e-20 69.9 26.8 1.4e-09 37.2 0.6 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat PAS PF00989.19 EJS44862.1 - 0.072 12.8 0.0 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 PAS fold SNF2_N PF00176.18 EJS44863.1 - 5.3e-74 248.7 1.1 5.3e-74 248.7 0.7 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EJS44863.1 - 2.2e-16 59.4 0.0 1.5e-13 50.4 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Collagen PF01391.13 EJS44863.1 - 0.013 14.9 6.5 0.023 14.2 4.5 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) AAA_22 PF13401.1 EJS44863.1 - 0.034 14.2 0.1 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain HhH-GPD PF00730.20 EJS44864.1 - 2.5e-21 75.9 0.0 4.7e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EJS44864.1 - 3.5e-08 32.6 0.0 1.6e-07 30.6 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EJS44864.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain SNARE PF05739.14 EJS44865.1 - 8.8e-09 34.9 1.7 8.8e-09 34.9 1.2 2.4 3 0 0 3 3 3 1 SNARE domain Cys_Met_Meta_PP PF01053.15 EJS44866.1 - 1.3e-143 477.9 0.0 1.5e-143 477.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EJS44866.1 - 0.00012 21.1 0.1 0.00026 20.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EJS44866.1 - 0.0093 14.7 0.3 0.028 13.1 0.1 1.8 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EJS44866.1 - 0.055 12.5 0.0 0.16 11.0 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase DUF3722 PF12519.3 EJS44868.1 - 1.7e-81 273.3 10.0 2.9e-81 272.5 6.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Spo7 PF03907.8 EJS44869.1 - 3.4e-92 307.7 6.3 4e-92 307.5 4.4 1.0 1 0 0 1 1 1 1 Spo7-like protein FUN14 PF04930.10 EJS44870.1 - 2.8e-13 49.9 1.5 5.3e-13 49.1 1.1 1.5 1 0 0 1 1 1 1 FUN14 family EMP24_GP25L PF01105.19 EJS44871.1 - 1.4e-33 116.1 0.1 1.7e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GP41 PF00517.12 EJS44871.1 - 0.062 12.8 0.7 0.079 12.5 0.5 1.3 1 0 0 1 1 1 0 Retroviral envelope protein DUF2922 PF11148.3 EJS44871.1 - 0.078 12.6 0.4 0.15 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) DUF2673 PF10880.3 EJS44871.1 - 0.083 12.9 0.9 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) PurS PF02700.9 EJS44871.1 - 0.13 12.1 1.3 0.27 11.2 0.9 1.5 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase DUF2189 PF09955.4 EJS44871.1 - 0.16 11.8 0.2 0.16 11.8 0.2 2.0 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) HSP70 PF00012.15 EJS44872.1 - 6e-274 909.5 8.7 6.8e-274 909.3 6.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EJS44872.1 - 6.7e-18 64.3 0.0 1.4e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EJS44872.1 - 0.0019 17.8 0.0 0.0046 16.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EJS44872.1 - 0.002 17.0 0.5 0.043 12.6 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Mrr_N PF14338.1 EJS44872.1 - 0.085 12.9 0.4 2 8.5 0.4 2.5 2 0 0 2 2 2 0 Mrr N-terminal domain Hydantoinase_A PF01968.13 EJS44872.1 - 0.11 11.5 1.8 0.37 9.8 0.0 2.4 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase EMP24_GP25L PF01105.19 EJS44873.1 - 6.8e-48 162.8 0.0 8.3e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Rep_fac-A_C PF08646.5 EJS44874.1 - 3.5e-59 198.7 1.9 2.4e-56 189.4 0.6 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EJS44874.1 - 2.5e-14 52.8 0.7 6.1e-09 35.6 0.0 4.2 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 EJS44874.1 - 2.2e-05 24.1 0.1 5.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.9 EJS44874.1 - 0.002 18.1 0.3 0.002 18.1 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function DUF223 BRCA-2_OB1 PF09103.5 EJS44874.1 - 0.01 15.5 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 SAICAR_synt PF01259.13 EJS44875.1 - 3.6e-102 340.7 0.0 4.2e-102 340.5 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Pkinase PF00069.20 EJS44876.1 - 2.5e-57 193.9 0.1 4.4e-57 193.2 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44876.1 - 1.8e-31 109.1 0.2 6.2e-30 104.1 0.1 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Phage_GPO PF05929.6 EJS44876.1 - 0.019 14.1 0.5 0.046 12.9 0.2 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Kinase-like PF14531.1 EJS44876.1 - 0.028 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ACCA PF03255.9 EJS44876.1 - 0.045 13.2 2.0 0.093 12.2 1.4 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SHNi-TPR PF10516.4 EJS44876.1 - 0.052 12.7 0.3 0.47 9.7 0.0 2.6 3 0 0 3 3 3 0 SHNi-TPR AAA_23 PF13476.1 EJS44876.1 - 3.6 7.8 11.6 1.7 8.9 6.2 1.9 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 EJS44877.1 - 9.2e-70 234.7 0.1 1.5e-69 234.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EJS44877.1 - 7.5e-53 179.2 0.0 1.2e-52 178.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EJS44877.1 - 0.00016 20.7 0.2 0.0041 16.1 0.0 2.6 3 0 0 3 3 3 1 Kinase-like DUF234 PF03008.9 EJS44877.1 - 0.11 12.6 0.8 9.9 6.3 0.0 3.4 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function ELFV_dehydrog PF00208.16 EJS44878.1 - 1.7e-81 273.4 2.7 2.1e-81 273.1 1.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EJS44878.1 - 1.1e-46 157.5 0.0 2.2e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain