# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DLIC PF05783.11 GAP82325.1 - 3.6e-32 111.8 0.0 5.9e-31 107.8 0.0 2.5 3 1 0 3 3 3 1 Dynein light intermediate chain (DLIC) Thioredox_DsbH PF03190.15 GAP82326.1 - 9.8e-51 171.9 0.0 1.9e-50 171.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Glyco_hydro_9 PF00759.19 GAP82326.1 - 0.013 14.9 0.6 0.023 14.1 0.6 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Thioredoxin_7 PF13899.6 GAP82326.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like GlcNAc_2-epim PF07221.11 GAP82326.1 - 0.034 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 GAP82326.1 - 0.039 13.5 3.1 0.061 12.8 0.6 2.2 2 1 1 3 3 3 0 Glycosyl hydrolase family 76 Sigma70_r4 PF04545.16 GAP82326.1 - 0.063 12.8 0.3 0.16 11.5 0.3 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 SOG2 PF10428.9 GAP82328.1 - 5.5 6.1 39.4 8.3 5.5 39.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ank_4 PF13637.6 GAP82329.1 - 1.9e-49 165.4 5.6 4.8e-12 46.1 0.1 8.5 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP82329.1 - 1.2e-45 154.0 2.7 4.8e-13 49.5 0.1 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP82329.1 - 4.9e-35 115.6 3.2 0.00032 20.9 0.0 9.6 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 GAP82329.1 - 2.4e-33 113.1 14.5 0.00013 22.2 0.0 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 GAP82329.1 - 5.8e-32 109.3 12.0 1.2e-08 35.1 0.2 6.4 3 2 3 6 6 6 5 Ankyrin repeats (many copies) CorA PF01544.18 GAP82329.1 - 1.9e-11 43.8 1.3 1.1e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein EMP70 PF02990.16 GAP82329.1 - 0.041 12.5 2.0 0.062 12.0 2.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Lipase_GDSL_2 PF13472.6 GAP82330.1 - 5.1e-12 46.6 0.1 8.4e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP82330.1 - 1.9e-11 44.4 0.0 2.6e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 GAP82330.1 - 0.00073 19.7 0.1 0.0016 18.6 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family FAD_binding_3 PF01494.19 GAP82333.1 - 1.3e-65 222.0 0.0 1.6e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Tannase PF07519.11 GAP82334.1 - 1.9e-87 294.2 0.6 3.6e-87 293.2 0.6 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Enterotoxin_ST PF02048.16 GAP82334.1 - 0.17 12.3 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 Heat-stable enterotoxin ST MFS_1 PF07690.16 GAP82335.1 - 2.4e-13 49.7 23.8 3.4e-13 49.2 23.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sulfatase PF00884.23 GAP82336.1 - 2e-59 201.5 1.0 2.5e-59 201.2 1.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 GAP82336.1 - 0.0011 19.3 0.1 0.0025 18.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) MFS_1 PF07690.16 GAP82337.1 - 1.2e-40 139.6 41.0 1.2e-40 139.6 41.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP82337.1 - 5.8e-07 28.7 33.9 8.1e-07 28.3 6.5 3.7 3 1 1 4 4 4 3 Sugar (and other) transporter OATP PF03137.20 GAP82337.1 - 0.015 13.7 0.6 0.015 13.7 0.6 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family OCD_Mu_crystall PF02423.15 GAP82338.1 - 3.7e-08 32.7 0.0 3.9e-07 29.3 0.0 2.3 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 GAP82338.1 - 7.4e-07 29.3 0.1 2.1e-05 24.6 0.1 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3530 PF12048.8 GAP82338.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DAO PF01266.24 GAP82339.1 - 1.5e-31 110.3 3.2 2.2e-31 109.7 3.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP82339.1 - 2.5e-07 30.8 0.0 8.1e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP82339.1 - 2.4e-05 23.7 0.0 0.0071 15.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP82339.1 - 4e-05 23.0 0.0 0.00024 20.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP82339.1 - 0.00066 19.7 0.1 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 GAP82339.1 - 0.00071 18.4 0.4 0.012 14.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 GAP82339.1 - 0.0013 17.9 4.5 0.0079 15.3 4.5 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAP82339.1 - 0.0055 16.0 0.2 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 GAP82339.1 - 0.0089 15.2 0.1 1.4 7.9 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 GAP82339.1 - 0.017 14.4 0.3 0.62 9.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ApbA PF02558.16 GAP82339.1 - 0.019 14.6 0.1 0.04 13.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 GAP82339.1 - 0.02 14.3 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 GAP82339.1 - 0.035 14.2 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 GAP82339.1 - 0.036 14.6 0.1 0.13 12.8 0.0 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAP82339.1 - 0.043 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Glu_dehyd_C PF16912.5 GAP82339.1 - 0.11 12.0 0.1 0.34 10.4 0.0 1.8 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 GAP82339.1 - 0.13 12.7 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 GAP82339.1 - 0.19 11.0 1.2 0.28 10.4 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pkinase PF00069.25 GAP82340.1 - 4.8e-29 101.5 0.0 1.9e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP82340.1 - 7.8e-10 38.5 0.0 0.00049 19.5 0.0 3.0 2 2 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GAP82340.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ILVD_EDD PF00920.21 GAP82342.1 - 1.2e-211 703.9 0.2 1.3e-211 703.7 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family HTH_25 PF13413.6 GAP82342.1 - 0.17 11.7 0.7 6.2 6.8 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Aa_trans PF01490.18 GAP82343.1 - 1e-22 80.4 26.5 2.7e-22 79.1 26.2 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Amino_oxidase PF01593.24 GAP82345.1 - 4.7e-46 158.0 0.0 6e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HNH_2 PF13391.6 GAP82346.1 - 2e-12 47.1 0.0 3.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease COesterase PF00135.28 GAP82347.1 - 3.5e-63 214.2 3.2 6.8e-62 210.0 3.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP82347.1 - 7.6e-14 52.1 0.5 5.3e-13 49.3 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP82347.1 - 0.00093 18.7 0.9 0.0017 17.9 0.9 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2235 PF09994.9 GAP82347.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DNApol_Exo PF18136.1 GAP82349.1 - 8.8e-102 340.0 0.2 1.7e-101 339.1 0.0 1.6 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 GAP82349.1 - 4.4e-57 193.9 0.0 7.8e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A Cmyb_C PF09316.10 GAP82349.1 - 0.029 14.0 0.2 0.45 10.2 0.1 2.4 1 1 1 2 2 2 0 C-myb, C-terminal MFS_1 PF07690.16 GAP82350.1 - 5.3e-40 137.4 47.3 5.3e-40 137.4 47.3 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Hydrolase_4 PF12146.8 GAP82351.1 - 9.9e-51 172.3 0.0 1.1e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAP82351.1 - 4.1e-16 60.3 0.3 5.1e-16 59.9 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP82351.1 - 6.3e-12 45.7 0.1 6.1e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.10 GAP82351.1 - 0.00025 20.2 0.0 0.00038 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) PGAP1 PF07819.13 GAP82351.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 GAP82351.1 - 0.02 14.5 0.2 0.042 13.5 0.2 1.4 1 1 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 GAP82351.1 - 0.068 13.3 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain MFS_1 PF07690.16 GAP82353.1 - 1.8e-09 37.0 17.9 2.3e-09 36.7 17.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 GAP82354.1 - 7.5e-58 196.4 0.0 1e-57 195.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ORC6 PF05460.13 GAP82355.1 - 0.16 11.2 12.8 0.26 10.5 12.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SR-25 PF10500.9 GAP82355.1 - 0.9 9.1 12.1 0.63 9.6 7.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ndc1_Nup PF09531.10 GAP82355.1 - 2.5 6.7 6.4 3.4 6.2 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 GAP82355.1 - 3.4 6.1 7.5 5.7 5.4 7.5 1.2 1 0 0 1 1 1 0 Macoilin family Dicty_REP PF05086.12 GAP82355.1 - 6.6 4.6 7.3 9 4.1 7.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MTP18 PF10558.9 GAP82357.1 - 0.069 13.1 0.1 0.11 12.4 0.1 1.3 1 1 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Abhydrolase_6 PF12697.7 GAP82358.1 - 8.3e-11 42.9 3.0 1.4e-10 42.2 3.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP82358.1 - 2.9e-09 36.6 0.1 4.4e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP82358.1 - 3.2e-05 23.7 0.1 4.7e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAP82358.1 - 3.5e-05 23.7 0.3 6e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP82358.1 - 0.00044 19.8 0.8 0.012 15.1 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydro_lipase PF04083.16 GAP82358.1 - 0.019 14.5 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF2244 PF10003.9 GAP82358.1 - 0.42 10.3 1.8 8.7 6.0 1.9 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Ank_5 PF13857.6 GAP82359.1 - 2.4e-21 75.5 0.4 1.3e-07 31.8 0.1 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP82359.1 - 6.2e-21 74.8 0.1 0.00059 20.4 0.0 4.8 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 GAP82359.1 - 2.6e-17 62.4 1.2 0.0024 18.2 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 GAP82359.1 - 3e-17 60.9 0.9 0.0053 17.2 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 GAP82359.1 - 5.6e-17 61.9 0.4 0.0012 19.4 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeats (many copies) NACHT PF05729.12 GAP82359.1 - 0.00049 20.0 0.0 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 NACHT domain FCH PF00611.23 GAP82359.1 - 0.0026 18.0 0.1 0.0078 16.5 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain AAA_16 PF13191.6 GAP82359.1 - 0.0081 16.6 0.0 0.027 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 GAP82359.1 - 0.042 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 GAP82359.1 - 0.057 13.1 0.7 0.7 9.6 0.0 3.0 4 0 0 4 4 4 0 AAA domain Glyco_hydro_3 PF00933.21 GAP82360.1 - 5.6e-19 68.7 0.0 2.3e-14 53.5 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Sas10_Utp3 PF04000.15 GAP82361.1 - 9.7e-17 61.4 0.5 9.7e-17 61.4 0.5 2.8 3 1 0 3 3 3 1 Sas10/Utp3/C1D family CDC45 PF02724.14 GAP82361.1 - 0.04 12.2 14.0 0.051 11.9 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.9 GAP82361.1 - 0.13 12.2 17.1 0.21 11.5 17.1 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2052 PF09747.9 GAP82361.1 - 0.19 11.9 12.8 0.25 11.5 12.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Peptidase_C37 PF05416.12 GAP82361.1 - 0.21 10.0 4.9 0.29 9.6 4.9 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase GAGA_bind PF06217.12 GAP82361.1 - 0.39 11.0 9.6 0.48 10.7 9.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Cytomega_UL84 PF06284.11 GAP82361.1 - 0.7 8.3 10.6 0.94 7.9 10.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RR_TM4-6 PF06459.12 GAP82361.1 - 1.2 8.9 13.5 1.5 8.6 13.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 GAP82361.1 - 4 7.1 6.1 5.3 6.7 6.1 1.3 1 0 0 1 1 1 0 Connexin ApbA PF02558.16 GAP82362.1 - 1.9e-10 40.6 0.0 3.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 GAP82362.1 - 1.4e-07 31.8 0.0 3.1e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal dsDNA_bind PF01984.20 GAP82363.1 - 2.3e-38 130.9 15.0 2.7e-38 130.7 15.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain cwf18 PF08315.12 GAP82363.1 - 0.0019 18.9 5.6 0.0022 18.6 5.6 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Fes1 PF08609.10 GAP82363.1 - 0.034 15.0 0.8 0.06 14.2 0.2 1.7 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 HWE_HK PF07536.14 GAP82363.1 - 0.23 12.2 4.6 0.15 12.8 1.4 2.3 1 1 0 2 2 2 0 HWE histidine kinase Yae1_N PF09811.9 GAP82364.1 - 1.2e-11 44.0 3.1 2.3e-11 43.2 3.1 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RraA-like PF03737.15 GAP82365.1 - 2.3e-35 122.0 0.0 2.8e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA MFS_1 PF07690.16 GAP82366.1 - 2.7e-30 105.5 43.8 1.1e-29 103.4 43.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP82366.1 - 4e-10 38.7 19.4 5.4e-10 38.3 19.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Asp PF00026.23 GAP82367.1 - 1.6e-62 211.8 0.2 2.7e-62 211.0 0.2 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP82367.1 - 1.5e-10 41.6 0.9 1.8e-08 34.8 0.4 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAP82367.1 - 0.0026 18.4 0.2 9.5 6.9 0.0 3.8 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 GAP82367.1 - 0.0076 16.8 0.1 11 6.6 0.0 3.7 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease G-patch PF01585.23 GAP82368.1 - 9.7e-10 38.2 1.3 2.1e-09 37.1 1.3 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 GAP82368.1 - 1e-08 34.9 0.1 0.0078 16.0 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 GAP82368.1 - 3.5e-07 29.4 2.9 6.2e-07 28.6 2.9 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 GAP82368.1 - 0.00016 21.7 2.1 0.00016 21.7 2.1 2.2 2 0 0 2 2 2 1 G-patch domain RED_N PF07808.13 GAP82368.1 - 0.0095 15.5 0.1 0.0095 15.5 0.1 2.8 4 0 0 4 4 4 1 RED-like protein N-terminal region zf-C2H2_11 PF16622.5 GAP82368.1 - 0.014 15.1 1.9 0.014 15.1 1.9 2.1 3 0 0 3 3 3 0 zinc-finger C2H2-type MT0933_antitox PF14013.6 GAP82368.1 - 0.077 13.3 4.1 0.21 11.9 4.1 1.8 1 0 0 1 1 1 0 MT0933-like antitoxin protein zf-met PF12874.7 GAP82368.1 - 2.7 8.5 6.0 0.47 10.9 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type AMP-binding PF00501.28 GAP82369.1 - 2e-80 270.5 0.0 3.7e-80 269.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 GAP82369.1 - 7.3e-68 228.9 0.0 1.3e-67 228.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 GAP82369.1 - 6.5e-55 186.6 0.0 1.2e-54 185.8 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 GAP82369.1 - 1.2e-54 184.9 2.6 2.9e-54 183.7 0.1 2.4 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 GAP82369.1 - 2.2e-50 172.0 0.0 4.1e-50 171.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAP82369.1 - 1.1e-48 166.0 0.0 2.2e-48 165.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAP82369.1 - 1.8e-30 105.4 0.0 7.1e-30 103.4 0.0 2.1 3 0 0 3 3 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAP82369.1 - 3.9e-21 75.6 0.0 1.1e-20 74.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_4 PF07993.12 GAP82369.1 - 3.8e-20 72.2 0.0 9.8e-20 70.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 GAP82369.1 - 7e-16 58.3 2.1 3.1e-07 30.6 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 GAP82369.1 - 2.2e-14 53.9 0.0 2.5e-13 50.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAP82369.1 - 1.8e-12 47.7 0.0 5.9e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 GAP82369.1 - 1.4e-11 44.5 0.0 4.4e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP82369.1 - 5.9e-11 42.9 0.0 1.6e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAP82369.1 - 3.2e-10 39.8 0.1 7.7e-10 38.5 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_31 PF13847.6 GAP82369.1 - 9.3e-10 38.5 0.0 3.1e-09 36.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.21 GAP82369.1 - 7.9e-09 35.3 0.0 1.6e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 GAP82369.1 - 0.00015 21.2 0.0 0.00073 19.0 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 GAP82369.1 - 0.00058 19.0 0.1 0.065 12.2 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 GAP82369.1 - 0.00076 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 GAP82369.1 - 0.0013 18.4 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_33 PF10017.9 GAP82369.1 - 0.014 14.6 0.0 0.035 13.3 0.0 1.6 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent RrnaAD PF00398.20 GAP82369.1 - 0.061 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GDP_Man_Dehyd PF16363.5 GAP82369.1 - 0.12 11.7 0.0 0.4 10.0 0.0 1.9 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase Methyltransf_16 PF10294.9 GAP82369.1 - 0.2 11.4 0.0 0.55 9.9 0.0 1.7 1 0 0 1 1 1 0 Lysine methyltransferase SAT PF16073.5 GAP82369.1 - 0.89 9.2 3.0 1.2 8.8 1.5 2.0 2 1 0 2 2 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis p450 PF00067.22 GAP82370.1 - 1.4e-23 83.4 0.0 2.7e-23 82.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 GAP82371.1 - 5.6e-16 58.5 0.0 8.3e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 GAP82371.1 - 0.00064 19.6 0.2 0.0014 18.6 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain Sulfatase PF00884.23 GAP82371.1 - 0.021 14.2 0.2 0.031 13.7 0.2 1.2 1 0 0 1 1 1 0 Sulfatase MFS_1 PF07690.16 GAP82372.1 - 7.6e-35 120.5 50.9 1.3e-34 119.7 49.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 GAP82372.1 - 1 7.6 22.1 0.027 12.8 1.4 3.6 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 GAP82373.1 - 1.5e-20 73.4 0.0 4.3e-20 71.9 0.0 1.7 3 0 0 3 3 3 1 Cytochrome P450 Methyltransf_2 PF00891.18 GAP82374.1 - 1.5e-15 57.1 0.0 2.5e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 GAP82374.1 - 0.0081 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain VPDSG-CTERM PF18205.1 GAP82375.1 - 0.17 11.8 2.0 0.5 10.2 2.0 1.9 1 0 0 1 1 1 0 VPDSG-CTERM motif CcmD PF04995.14 GAP82375.1 - 0.21 11.7 2.0 0.22 11.6 0.3 1.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) MFS_1 PF07690.16 GAP82376.1 - 2.4e-47 161.6 24.3 2.4e-47 161.6 24.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP82376.1 - 3.3e-12 46.0 12.8 3.3e-12 46.0 12.8 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAP82376.1 - 4.8e-05 22.0 5.7 7.9e-05 21.3 5.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 GAP82376.1 - 0.0011 17.5 1.3 0.0011 17.5 1.3 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.20 GAP82376.1 - 0.05 11.9 2.3 0.44 8.8 1.7 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family HTH_36 PF13730.6 GAP82376.1 - 0.074 13.0 0.0 21 5.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain MFS_1_like PF12832.7 GAP82376.1 - 0.37 9.6 14.2 0.14 11.0 6.4 2.8 2 1 0 2 2 2 0 MFS_1 like family GMC_oxred_N PF00732.19 GAP82378.1 - 1.3e-15 57.5 0.0 1.4e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAP82378.1 - 3.4e-06 26.4 0.2 5e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAP82378.1 - 0.00029 20.2 0.2 0.00029 20.2 0.2 1.6 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 GAP82378.1 - 0.0012 17.8 0.4 0.0017 17.3 0.4 1.2 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 GAP82378.1 - 0.0017 18.0 0.9 0.002 17.8 0.2 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP82378.1 - 0.0054 16.0 0.1 0.0059 15.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP82378.1 - 0.0074 16.5 0.2 0.019 15.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAP82378.1 - 0.025 13.7 0.2 0.037 13.1 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAP82378.1 - 0.12 11.0 0.4 0.18 10.5 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.21 GAP82378.1 - 0.14 11.5 0.4 0.2 11.0 0.4 1.2 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.19 GAP82378.1 - 0.17 11.1 0.1 0.22 10.7 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 GAP82380.1 - 1.3e-43 149.3 48.8 4.9e-43 147.4 48.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP82380.1 - 1.2e-17 63.6 18.2 1.2e-17 63.6 18.2 1.9 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2_1 PF04971.12 GAP82380.1 - 0.29 11.2 4.0 20 5.3 0.1 3.3 2 0 0 2 2 2 0 Bacteriophage P21 holin S p450 PF00067.22 GAP82381.1 - 4e-32 111.6 0.0 1.1e-29 103.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Methyltransf_2 PF00891.18 GAP82382.1 - 4.4e-23 81.7 0.0 7.1e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAP82382.1 - 0.028 15.1 0.0 0.071 13.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_1_2 PF00155.21 GAP82383.1 - 1.5e-46 159.3 0.0 2.1e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAP82383.1 - 0.039 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase HA PF03457.14 GAP82383.1 - 0.18 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 Helicase associated domain AMP-binding PF00501.28 GAP82384.1 - 2.1e-53 181.5 0.0 2.9e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 GAP82384.1 - 4.8e-22 79.2 0.8 3.4e-19 69.9 0.1 3.3 3 1 0 3 3 3 2 Thioesterase domain PP-binding PF00550.25 GAP82384.1 - 4.2e-10 39.8 0.1 1.2e-09 38.3 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site GH3 PF03321.13 GAP82384.1 - 0.0078 15.1 0.1 0.043 12.7 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Abhydrolase_6 PF12697.7 GAP82384.1 - 0.072 13.7 11.6 0.013 16.1 6.6 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hjc PF01870.18 GAP82384.1 - 0.073 13.1 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) Abhydrolase_1 PF00561.20 GAP82384.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold HSP90 PF00183.18 GAP82385.1 - 2e-36 126.0 21.9 2.7e-36 125.6 21.9 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 GAP82385.1 - 5.9e-16 59.0 0.0 9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAP82385.1 - 5.2e-11 42.5 0.1 5.2e-11 42.5 0.1 1.9 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RNA_pol_Rpc4 PF05132.14 GAP82385.1 - 2.8 8.4 6.1 4.5 7.7 6.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 GAP82385.1 - 6.3 5.7 7.0 24 3.8 5.3 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) YqfQ PF14181.6 GAP82385.1 - 8.4 6.6 12.0 16 5.6 12.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.14 GAP82385.1 - 9.5 4.4 12.9 13 3.9 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.18 GAP82387.1 - 2.2e-123 412.9 13.0 2.6e-123 412.7 13.0 1.0 1 0 0 1 1 1 1 Hsp90 protein UPF0113_N PF17833.1 GAP82387.1 - 0.006 17.1 0.8 1.1 9.9 0.2 3.3 2 1 0 2 2 2 1 UPF0113 Pre-PUA domain PhoU PF01895.19 GAP82387.1 - 0.023 15.2 0.2 0.023 15.2 0.2 2.2 2 0 0 2 2 2 0 PhoU domain DUF5024 PF16427.5 GAP82387.1 - 0.077 13.3 7.7 0.16 12.3 1.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5024) AbiH PF14253.6 GAP82387.1 - 1 9.2 6.6 0.49 10.2 0.2 2.3 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH Peptidase_M28 PF04389.17 GAP82389.1 - 4.1e-33 114.7 0.0 6.8e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAP82389.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 p450 PF00067.22 GAP82390.1 - 1.3e-27 96.7 0.0 2.1e-26 92.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 GAP82392.1 - 2.9e-48 164.8 0.0 3.9e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec34 PF04136.15 GAP82392.1 - 0.046 13.6 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Sec34-like family LMWPc PF01451.21 GAP82394.1 - 2.7e-37 128.3 0.0 3.1e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.25 GAP82395.1 - 9.5e-69 231.7 0.0 1.2e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP82395.1 - 1.5e-31 109.7 0.0 3.4e-31 108.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAP82395.1 - 0.014 14.4 0.0 0.028 13.3 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAP82395.1 - 0.05 12.9 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP82395.1 - 0.053 13.4 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3455 PF11937.8 GAP82396.1 - 1.6e-25 90.3 0.0 2.1e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) MPC PF03650.13 GAP82397.1 - 2.5e-46 156.3 0.7 3.2e-46 156.0 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF5363 PF17320.2 GAP82397.1 - 0.18 11.7 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5363) DUF1206 PF06724.11 GAP82397.1 - 6.4 6.9 6.4 14 5.8 2.2 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) SURF1 PF02104.15 GAP82398.1 - 4.1e-39 134.6 0.6 2.2e-38 132.2 0.6 1.9 1 1 0 1 1 1 1 SURF1 family IMUP PF15761.5 GAP82398.1 - 0.1 13.3 1.3 0.18 12.5 1.3 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Dicty_REP PF05086.12 GAP82398.1 - 0.9 7.4 1.5 1.2 7.1 1.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CENP-T_C PF15511.6 GAP82399.1 - 7.4e-47 157.9 0.0 1.3e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAP82399.1 - 6.6e-09 36.0 0.1 1.3e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 GAP82399.1 - 2.4e-05 24.7 0.0 7.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAP82399.1 - 0.00013 22.2 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone p450 PF00067.22 GAP82401.1 - 3e-18 65.8 0.0 4.5e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF4371 PF14291.6 GAP82401.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4371) NmrA PF05368.13 GAP82402.1 - 5e-20 72.1 0.0 6.7e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP82402.1 - 2.4e-15 56.9 0.0 4.2e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding p450 PF00067.22 GAP82404.1 - 9e-54 182.9 0.0 1.2e-53 182.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zip PF02535.22 GAP82408.1 - 1.2e-31 110.2 46.6 1.3e-14 54.2 5.2 4.2 4 1 1 5 5 5 3 ZIP Zinc transporter DUF3611 PF12263.8 GAP82408.1 - 0.012 15.5 4.8 0.032 14.1 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Fe-ADH PF00465.19 GAP82410.1 - 5e-64 216.4 0.3 7e-64 215.9 0.3 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAP82410.1 - 6.1e-06 26.1 1.3 5.8e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 GAP82410.1 - 0.045 12.9 0.1 0.089 11.9 0.1 1.4 1 0 0 1 1 1 0 3-dehydroquinate synthase CAP_N PF01213.19 GAP82410.1 - 1.1 8.7 1.9 1.7 8.0 1.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HET PF06985.11 GAP82411.1 - 6.7e-33 114.1 0.0 1.3e-32 113.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_fungal PF17667.1 GAP82412.1 - 2.3e-126 421.9 0.6 2.9e-126 421.6 0.6 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 GAP82412.1 - 1.9e-08 34.0 0.0 3.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP82412.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-MYND PF01753.18 GAP82413.1 - 3.5e-08 33.4 13.1 7.7e-08 32.3 13.1 1.6 1 0 0 1 1 1 1 MYND finger SET PF00856.28 GAP82413.1 - 9.6e-08 32.6 0.3 1.8e-07 31.7 0.3 1.4 1 0 0 1 1 1 1 SET domain UBX PF00789.20 GAP82414.1 - 2.4e-10 40.5 0.0 4.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain Mucin PF01456.17 GAP82414.1 - 0.0035 17.3 13.7 0.0081 16.2 6.0 2.4 2 0 0 2 2 2 2 Mucin-like glycoprotein MRP-S31 PF15433.6 GAP82414.1 - 0.14 11.8 13.0 0.19 11.3 13.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TFIIA PF03153.13 GAP82414.1 - 0.37 10.7 9.6 0.46 10.4 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 GAP82414.1 - 0.49 9.7 16.6 0.66 9.3 16.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BAF1_ABF1 PF04684.13 GAP82414.1 - 8.4 5.3 12.7 13 4.7 12.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Amidase PF01425.21 GAP82415.1 - 3e-73 247.3 1.0 1.6e-67 228.4 0.1 2.3 2 1 0 2 2 2 2 Amidase Amidase PF01425.21 GAP82416.1 - 6.9e-19 68.1 2.1 6.9e-19 68.1 2.1 1.6 2 0 0 2 2 2 1 Amidase SnoaL_2 PF12680.7 GAP82418.1 - 0.11 13.2 0.0 0.2 12.3 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain p450 PF00067.22 GAP82419.1 - 1.9e-27 96.1 0.0 3.5e-26 92.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Porphobil_deam PF01379.20 GAP82420.1 - 1.6e-05 24.5 0.1 1.8e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain K1 PF02960.14 GAP82422.1 - 0.14 12.3 0.0 6.8 6.8 0.0 2.6 2 0 0 2 2 2 0 K1 glycoprotein Methyltransf_33 PF10017.9 GAP82423.1 - 1.7e-80 270.5 0.0 2.1e-80 270.1 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FAM199X PF15814.5 GAP82425.1 - 4.6 6.2 6.5 7.2 5.6 6.5 1.3 1 0 0 1 1 1 0 Protein family FAM199X DUF676 PF05057.14 GAP82427.1 - 0.089 12.3 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) CorA PF01544.18 GAP82429.1 - 1.7e-07 30.9 0.2 2.4e-07 30.4 0.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Phos_pyr_kin PF08543.12 GAP82431.1 - 4.7e-10 39.3 0.6 1.1e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 GAP82431.1 - 1.7e-06 27.6 2.6 1.1e-05 24.9 0.0 2.8 2 1 1 3 3 3 1 pfkB family carbohydrate kinase FOXP-CC PF16159.5 GAP82432.1 - 9.5e-05 23.0 13.0 0.00039 21.0 1.1 3.0 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 GAP82432.1 - 0.0012 19.1 0.1 0.0017 18.6 0.1 1.3 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 GAP82432.1 - 0.0016 19.1 15.3 0.017 15.9 0.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger YwqJ-deaminase PF14431.6 GAP82432.1 - 0.03 14.5 0.8 0.078 13.2 0.1 1.9 2 0 0 2 2 2 0 YwqJ-like deaminase zf-Di19 PF05605.12 GAP82432.1 - 0.04 14.2 3.9 0.04 14.2 3.9 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 GAP82432.1 - 0.047 14.2 1.0 0.047 14.2 1.0 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 GAP82432.1 - 0.45 10.0 4.0 1.1 8.8 0.8 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 GAP82432.1 - 0.52 10.5 3.0 0.78 9.9 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain PADR1 PF08063.12 GAP82432.1 - 0.58 10.0 7.0 1.5 8.7 0.3 2.6 2 1 0 2 2 2 0 PADR1 (NUC008) domain KRTAP PF11759.8 GAP82432.1 - 3 8.5 28.1 11 6.6 28.1 2.0 1 1 0 1 1 1 0 Keratin-associated matrix FAA_hydrolase PF01557.18 GAP82433.1 - 7.3e-66 221.9 0.0 1e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.7 GAP82433.1 - 6.1e-12 46.6 9.9 6.1e-12 46.6 9.9 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP82433.1 - 9.2e-12 44.7 0.1 1.6e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP82433.1 - 7.7e-11 42.1 0.1 1.3e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 GAP82433.1 - 4.1e-05 23.5 0.1 8.5e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_8 PF06259.12 GAP82433.1 - 0.0057 16.3 0.9 0.42 10.2 0.1 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase PhrC_PhrF PF11131.8 GAP82433.1 - 0.079 12.6 1.9 0.29 10.7 1.9 1.9 1 0 0 1 1 1 0 Rap-phr extracellular signalling DAO PF01266.24 GAP82434.1 - 2.9e-21 76.4 2.3 4e-21 76.0 2.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Hydrolase_4 PF12146.8 GAP82435.1 - 2.5e-06 26.9 0.0 5.8e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP82435.1 - 0.00016 21.4 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 GAP82435.1 - 0.00089 18.0 0.0 0.0013 17.5 0.0 1.1 1 0 0 1 1 1 1 Ndr family Serglycin PF04360.12 GAP82436.1 - 0.16 11.9 1.3 0.33 10.9 1.3 1.6 1 0 0 1 1 1 0 Serglycin TauD PF02668.16 GAP82437.1 - 7.1e-32 111.3 0.1 9.1e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSNAXIP1_N PF15739.5 GAP82438.1 - 0.00044 20.6 0.7 0.00044 20.6 0.7 1.7 1 1 1 2 2 2 1 Translin-associated factor X-interacting N-terminus DUF4687 PF15747.5 GAP82440.1 - 0.15 12.5 1.0 0.38 11.3 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) DUF2236 PF09995.9 GAP82441.1 - 3.1e-10 40.6 2.3 4.2e-10 40.2 1.7 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) LisH_2 PF16045.5 GAP82441.1 - 0.1 11.6 0.1 0.28 10.3 0.1 1.7 2 0 0 2 2 2 0 LisH FAD_binding_3 PF01494.19 GAP82443.1 - 8.2e-08 31.9 0.4 5.3e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain RuBisCO_large PF00016.20 GAP82444.1 - 0.087 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain NMT1 PF09084.11 GAP82445.1 - 1.9e-10 41.1 0.0 2.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 GAP82445.1 - 0.009 15.5 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 GAP82445.1 - 0.015 14.8 0.0 0.017 14.6 0.0 1.3 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 zf-C2H2 PF00096.26 GAP82446.1 - 3.7e-10 39.7 8.4 4.4e-05 23.7 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP82446.1 - 2.2e-06 28.0 7.0 0.011 16.5 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 GAP82446.1 - 0.048 13.8 4.8 0.13 12.4 0.4 2.2 1 1 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 GAP82446.1 - 8 7.1 15.9 0.3 11.6 2.9 3.3 3 0 0 3 3 3 0 Zinc-finger double domain DSPc PF00782.20 GAP82447.1 - 1.6e-10 40.9 0.0 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAP82447.1 - 0.00025 20.7 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 GAP82447.1 - 0.00056 19.9 0.0 0.00087 19.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPn PF14671.6 GAP82447.1 - 0.039 14.4 0.0 0.063 13.7 0.0 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 GAP82447.1 - 0.094 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 GAP82447.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Mito_carr PF00153.27 GAP82448.1 - 2e-26 91.8 2.1 8.1e-17 60.9 0.5 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein DUF4834 PF16118.5 GAP82448.1 - 3.4 8.7 7.8 13 6.8 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 GAP82448.1 - 4.2 6.9 13.6 0.89 9.1 6.8 2.0 2 0 0 2 2 2 0 Spt20 family SUIM_assoc PF16619.5 GAP82448.1 - 6.4 6.9 17.4 0.46 10.6 9.1 2.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Zn_clus PF00172.18 GAP82449.1 - 0.0003 20.8 11.3 0.00064 19.8 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 GAP82450.1 - 4.1e-11 42.7 0.0 6.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP82450.1 - 8e-06 25.6 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP82450.1 - 1.1e-05 25.5 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 GAP82450.1 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family T2SSE_N PF05157.15 GAP82450.1 - 0.032 14.5 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain Semialdhyde_dh PF01118.24 GAP82450.1 - 0.049 14.1 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 GAP82453.1 - 9.2e-05 22.1 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DnaJ PF00226.31 GAP82454.1 - 2.5e-21 75.6 3.7 2.8e-21 75.4 1.0 2.3 2 0 0 2 2 2 1 DnaJ domain INCENP_ARK-bind PF03941.15 GAP82455.1 - 6.4e-18 64.5 1.5 6.4e-18 64.5 1.5 3.3 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region NOT2_3_5 PF04153.18 GAP82456.1 - 7e-27 94.1 3.8 1.3e-26 93.3 3.8 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF4448 PF14610.6 GAP82456.1 - 0.17 11.7 0.2 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) cobW PF02492.19 GAP82457.1 - 1.7e-48 164.5 0.3 2.3e-48 164.1 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 GAP82457.1 - 1.7e-05 24.8 0.2 0.2 11.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 GAP82457.1 - 0.0008 18.5 1.1 1.6 7.6 0.1 3.1 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 GAP82457.1 - 0.0047 16.7 0.4 0.032 14.0 0.4 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein PND PF17949.1 GAP82457.1 - 0.007 16.6 0.2 0.031 14.5 0.1 2.0 2 0 0 2 2 2 1 FANCM pseudonuclease domain AAA_30 PF13604.6 GAP82457.1 - 0.0071 16.1 0.8 0.49 10.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAP82457.1 - 0.0086 16.2 0.0 0.019 15.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAP82457.1 - 0.017 14.6 2.4 0.38 10.3 2.4 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 GAP82457.1 - 0.018 15.5 0.1 0.035 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAP82457.1 - 0.02 14.9 0.1 0.063 13.3 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GAP82457.1 - 0.027 14.8 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAP82457.1 - 0.027 14.7 0.2 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain CobW_C PF07683.14 GAP82457.1 - 0.041 13.8 0.1 0.083 12.8 0.1 1.5 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Zeta_toxin PF06414.12 GAP82457.1 - 0.042 13.1 0.1 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 GAP82457.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 GAP82457.1 - 0.24 11.2 0.0 0.24 11.2 0.0 2.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain p450 PF00067.22 GAP82458.1 - 5.5e-57 193.5 0.0 6.6e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GvpL_GvpF PF06386.11 GAP82458.1 - 0.032 14.2 0.1 0.044 13.7 0.1 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Mob1_phocein PF03637.17 GAP82459.1 - 1.1e-22 80.9 0.1 1.8e-22 80.2 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Fungal_trans_2 PF11951.8 GAP82460.1 - 3.4e-11 42.6 0.3 1.4e-10 40.6 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP82460.1 - 8.5e-07 29.0 10.6 1.7e-06 28.0 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOSC PF03473.17 GAP82461.1 - 8.1e-22 77.6 0.0 1.5e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 GAP82461.1 - 5.9e-13 48.8 0.0 1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SMC_N PF02463.19 GAP82462.1 - 4.5e-66 222.4 16.7 4.8e-65 219.1 16.7 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAP82462.1 - 2.2e-21 76.3 0.7 1.3e-20 73.8 0.3 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAP82462.1 - 3.4e-07 30.4 12.3 0.0015 18.4 0.0 4.3 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system HIP1_clath_bdg PF16515.5 GAP82462.1 - 0.0008 20.0 9.1 0.0008 20.0 9.1 8.6 3 2 6 9 9 9 1 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_29 PF13555.6 GAP82462.1 - 0.001 18.7 0.1 0.0025 17.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4250 PF14056.6 GAP82462.1 - 0.0046 16.9 0.8 1.9 8.5 0.3 4.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4250) ABC_tran PF00005.27 GAP82462.1 - 0.078 13.5 0.0 0.078 13.5 0.0 6.1 3 2 1 5 5 5 0 ABC transporter Sacchrp_dh_NADP PF03435.18 GAP82463.1 - 3.3e-09 37.1 0.2 8.1e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain CUE PF02845.16 GAP82464.1 - 1.9e-07 30.7 0.0 2.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain UMP1 PF05348.11 GAP82464.1 - 0.06 13.6 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 Cue1_U7BR PF18499.1 GAP82464.1 - 0.43 10.7 1.6 0.78 9.8 1.3 1.6 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 G2BR PF18442.1 GAP82464.1 - 0.71 9.6 9.3 1.5 8.5 9.3 1.5 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) DEAD PF00270.29 GAP82466.1 - 3.8e-28 98.4 0.0 1.1e-26 93.7 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP82466.1 - 8.5e-21 74.4 0.0 7e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAP82466.1 - 0.034 13.4 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 GAP82467.1 - 3.1e-17 62.6 10.2 0.013 16.4 0.2 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP82467.1 - 0.00017 21.8 0.1 0.22 11.8 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain 2OG-FeII_Oxy_2 PF13532.6 GAP82468.1 - 4.9e-36 124.8 0.1 6.5e-36 124.4 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.16 GAP82468.1 - 1.5e-06 27.7 0.1 2.7e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 CUE domain zf-GRF PF06839.12 GAP82468.1 - 0.026 14.6 0.2 0.059 13.5 0.0 1.7 2 0 0 2 2 2 0 GRF zinc finger E2_bind PF08825.10 GAP82468.1 - 0.068 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 E2 binding domain MFS_1 PF07690.16 GAP82469.1 - 9.6e-23 80.7 17.7 1.1e-22 80.4 17.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP82469.1 - 1.6e-05 23.9 3.6 2e-05 23.6 3.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 GAP82469.1 - 8.6e-05 22.0 1.5 9.9e-05 21.8 1.5 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PUCC PF03209.15 GAP82469.1 - 0.19 10.7 5.5 0.26 10.3 5.5 1.1 1 0 0 1 1 1 0 PUCC protein GFA PF04828.14 GAP82470.1 - 4.8e-06 26.8 16.2 0.00021 21.6 0.4 3.0 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme DUF2321 PF10083.9 GAP82470.1 - 0.041 13.5 4.0 0.06 13.0 1.9 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Rsm1 PF08600.10 GAP82470.1 - 0.11 12.7 1.5 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Rsm1-like DUF2116 PF09889.9 GAP82470.1 - 0.96 9.5 6.5 0.38 10.8 0.8 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PRA1 PF03208.19 GAP82472.1 - 0.031 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 PRA1 family protein AT_hook PF02178.19 GAP82473.1 - 0.11 12.4 20.1 0.24 11.4 5.4 3.3 2 0 0 2 2 2 0 AT hook motif NTS PF15447.6 GAP82474.1 - 0.3 11.6 1.7 15 6.2 0.1 2.4 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 Fungal_trans PF04082.18 GAP82475.1 - 1e-25 90.3 0.0 1.6e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP82475.1 - 2.9e-08 33.7 10.9 4.5e-08 33.1 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 GAP82476.1 - 1.1e-20 73.8 28.3 9.9e-20 70.7 28.3 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 GAP82477.1 - 1.5e-35 122.8 22.5 1.1e-31 110.1 0.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP82477.1 - 6.9e-09 35.1 1.6 1.6e-08 33.9 1.6 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 GAP82477.1 - 0.0065 14.9 0.7 0.011 14.2 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Coq4 PF05019.13 GAP82478.1 - 1.1e-74 250.5 0.0 1.2e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 CYSTM PF12734.7 GAP82479.1 - 8.3 6.8 73.9 0.04 14.2 34.5 4.5 2 1 1 3 3 3 0 Cysteine-rich TM module stress tolerance UQ_con PF00179.26 GAP82481.1 - 1.3e-10 41.1 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MGTL PF17059.5 GAP82482.1 - 0.0023 17.6 2.5 0.0095 15.7 2.5 2.1 1 0 0 1 1 1 1 MgtA leader peptide DAGK_cat PF00781.24 GAP82482.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Ras PF00071.22 GAP82483.1 - 2.6e-62 209.2 0.1 2.9e-62 209.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP82483.1 - 2.6e-35 121.3 0.2 3.3e-35 120.9 0.2 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP82483.1 - 3.3e-13 49.5 0.0 3.8e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAP82483.1 - 5.7e-08 32.8 0.1 7.8e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAP82483.1 - 0.00023 20.6 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAP82483.1 - 0.00029 20.4 0.1 0.0012 18.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAP82483.1 - 0.00047 20.1 0.6 0.011 15.6 0.1 2.1 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 GAP82483.1 - 0.00048 20.4 0.0 0.0045 17.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 GAP82483.1 - 0.008 15.6 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 GAP82483.1 - 0.0091 16.0 0.1 0.021 14.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 GAP82483.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 GAP82483.1 - 0.015 15.8 0.1 0.024 15.2 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 GAP82483.1 - 0.018 14.8 0.1 0.039 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAP82483.1 - 0.024 15.0 0.1 0.033 14.6 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 GAP82483.1 - 0.054 13.3 0.6 0.11 12.3 0.6 1.6 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 GAP82483.1 - 0.068 12.7 0.0 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B MCM PF00493.23 GAP82483.1 - 0.074 12.1 0.0 0.14 11.2 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 GAP82483.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FAD-SLDH PF12318.8 GAP82483.1 - 0.09 12.8 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_5 PF07728.14 GAP82483.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 GAP82483.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PfkB PF00294.24 GAP82484.1 - 9.5e-46 156.5 2.9 2e-45 155.4 2.9 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phostensin PF13914.6 GAP82484.1 - 0.11 13.2 0.1 0.19 12.3 0.1 1.4 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region Inositol_P PF00459.25 GAP82485.1 - 1.5e-59 201.8 0.1 1.8e-59 201.5 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PH PF00169.29 GAP82489.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 PH domain eIF3g PF12353.8 GAP82490.1 - 2.3e-44 150.8 2.7 3.6e-44 150.2 2.7 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 GAP82490.1 - 9.6e-15 54.2 0.0 1.9e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 GAP82490.1 - 0.016 15.5 0.1 0.03 14.7 0.1 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 GAP82490.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif PEMT PF04191.13 GAP82491.1 - 4.9e-57 190.9 10.6 9.7e-35 119.2 1.8 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 GAP82491.1 - 0.0043 16.9 0.2 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 PGA2 PF07543.12 GAP82492.1 - 1.8 8.6 7.2 5.9 6.9 1.4 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Spt5_N PF11942.8 GAP82492.1 - 2.6 9.1 11.1 6.4 7.8 1.8 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal HeLo PF14479.6 GAP82493.1 - 0.00031 20.6 0.3 0.0036 17.2 0.0 2.8 2 1 1 3 3 3 1 Prion-inhibition and propagation Kinase-like PF14531.6 GAP82493.1 - 0.014 14.8 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pkinase_Tyr PF07714.17 GAP82493.1 - 0.12 11.6 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Ank_2 PF12796.7 GAP82494.1 - 1.8e-34 118.2 0.0 1.2e-11 45.0 0.1 6.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP82494.1 - 6.3e-30 103.2 6.9 1.7e-06 28.5 0.1 7.6 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP82494.1 - 4e-28 97.1 4.4 6.7e-08 32.6 0.1 8.3 7 1 2 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP82494.1 - 1e-25 87.0 9.7 0.0023 18.3 0.0 9.2 8 0 0 8 8 8 6 Ankyrin repeat Pkinase PF00069.25 GAP82494.1 - 1.7e-23 83.4 0.0 2.7e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.30 GAP82494.1 - 1.1e-21 76.3 19.8 0.011 16.1 0.1 9.4 9 0 0 9 9 9 7 Ankyrin repeat Pkinase_Tyr PF07714.17 GAP82494.1 - 4.1e-19 68.9 0.0 6.8e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP82494.1 - 0.0026 16.6 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sel1 PF08238.12 GAP82494.1 - 0.021 15.5 0.0 0.05 14.3 0.0 1.6 1 0 0 1 1 1 0 Sel1 repeat AnkUBD PF18418.1 GAP82494.1 - 0.16 12.2 0.0 52 4.1 0.0 3.5 3 0 0 3 3 3 0 Ankyrin ubiquitin-binding domain ADH_zinc_N PF00107.26 GAP82495.1 - 2.7e-07 30.6 0.0 5.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP82495.1 - 0.00054 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PHO4 PF01384.20 GAP82495.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphate transporter family NAD_binding_8 PF13450.6 GAP82496.1 - 0.0051 17.0 0.9 0.01 16.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAP82496.1 - 0.018 14.3 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain adh_short_C2 PF13561.6 GAP82497.1 - 1.2e-54 185.3 4.6 2.2e-54 184.5 4.6 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP82497.1 - 3.8e-38 130.9 0.9 6.9e-38 130.1 0.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP82497.1 - 1.9e-08 34.4 3.2 8.8e-08 32.3 1.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAP82497.1 - 0.012 15.1 2.9 0.33 10.4 0.3 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 GAP82497.1 - 0.24 10.8 2.4 0.7 9.2 0.3 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pec_lyase_C PF00544.19 GAP82498.1 - 3e-16 59.6 12.6 1e-14 54.6 12.5 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GAP82498.1 - 0.0028 17.5 17.6 0.063 13.1 1.7 2.3 1 1 1 2 2 2 2 Right handed beta helix region AP_endonuc_2 PF01261.24 GAP82499.1 - 9e-27 93.9 0.2 1.2e-26 93.4 0.2 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sugar_tr PF00083.24 GAP82500.1 - 3.5e-108 362.4 20.2 4.2e-108 362.1 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP82500.1 - 2.1e-22 79.5 50.6 1.1e-21 77.1 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 GAP82501.1 - 2.3e-30 105.9 0.0 2.9e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP82501.1 - 1.7e-12 47.7 0.0 3.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP82501.1 - 2e-07 30.6 0.0 2.5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP82501.1 - 5.7e-07 29.0 0.0 1.7e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 GAP82501.1 - 2.2e-05 24.2 0.6 0.13 11.8 0.1 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAP82501.1 - 0.00043 19.5 0.3 0.37 9.8 0.1 2.5 2 1 1 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.14 GAP82501.1 - 0.0026 16.7 0.1 0.99 8.2 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 GAP82501.1 - 0.0049 15.6 0.0 1.7 7.2 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 GAP82501.1 - 0.029 14.4 2.7 3.8 7.5 0.0 3.2 2 1 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 GAP82501.1 - 0.033 14.6 0.2 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding adh_short_C2 PF13561.6 GAP82502.1 - 2.4e-53 181.1 0.2 2.9e-53 180.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP82502.1 - 5.2e-45 153.3 0.3 6.4e-45 153.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP82502.1 - 7.2e-14 52.1 0.5 9.7e-14 51.7 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAP82502.1 - 0.00024 21.1 0.1 0.00039 20.4 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 GAP82502.1 - 0.0012 18.4 0.1 0.0043 16.5 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 GAP82502.1 - 0.009 16.7 0.2 0.036 14.8 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 GAP82502.1 - 0.0097 15.1 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox_2 PF07992.14 GAP82502.1 - 0.01 15.1 0.1 0.022 14.0 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAP82502.1 - 0.019 15.2 0.1 0.045 14.0 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_31 PF13847.6 GAP82502.1 - 0.023 14.5 0.0 0.13 12.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox PF00070.27 GAP82502.1 - 0.024 15.2 0.1 0.18 12.4 0.1 2.4 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAP82502.1 - 0.062 12.7 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.14 GAP82502.1 - 0.082 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 GAP82502.1 - 0.16 12.7 0.1 0.62 10.8 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain AP_endonuc_2 PF01261.24 GAP82503.1 - 2.5e-25 89.2 0.0 3.9e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MecA PF05389.12 GAP82504.1 - 0.012 15.2 0.3 0.013 15.1 0.3 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) P_C10 PF14974.6 GAP82504.1 - 0.013 15.5 0.3 0.026 14.6 0.2 1.5 1 1 1 2 2 2 0 Protein C10 DUF3813 PF12758.7 GAP82504.1 - 0.034 14.5 2.4 4.1 7.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) DUF2397 PF09660.10 GAP82504.1 - 0.04 12.8 0.0 0.075 11.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2397) IL12 PF03039.14 GAP82505.1 - 0.12 11.7 0.6 0.45 9.8 0.1 1.9 2 0 0 2 2 2 0 Interleukin-12 alpha subunit Peptidase_C97 PF05903.14 GAP82507.1 - 4.5e-05 23.3 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain DnaJ PF00226.31 GAP82508.1 - 1.4e-09 37.9 0.2 3.4e-09 36.7 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain Syntaxin PF00804.25 GAP82508.1 - 0.42 10.3 2.7 0.27 10.9 0.7 1.6 1 1 0 1 1 1 0 Syntaxin DUF4407 PF14362.6 GAP82508.1 - 1.4 8.2 7.5 1.9 7.8 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IMUP PF15761.5 GAP82508.1 - 1.5 9.6 7.1 0.92 10.2 2.1 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein AATF-Che1 PF13339.6 GAP82508.1 - 2.2 9.0 8.1 0.26 12.0 1.3 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF3678 PF12435.8 GAP82508.1 - 4.2 6.8 9.5 8.7 5.8 9.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) PAP1 PF08601.10 GAP82508.1 - 8.8 5.9 8.4 12 5.5 8.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Nucleos_tra2_C PF07662.13 GAP82509.1 - 2.5e-72 243.1 3.9 2.5e-72 243.1 3.9 2.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 GAP82509.1 - 3.3e-21 75.7 2.3 3.3e-21 75.7 2.3 3.7 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus DUF5518 PF17647.1 GAP82509.1 - 0.013 15.7 1.8 0.013 15.7 1.8 5.7 6 0 0 6 6 6 0 Family of unknown function (DUF5518) ATP1G1_PLM_MAT8 PF02038.16 GAP82509.1 - 2.8 7.4 6.0 2 7.9 3.3 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family p450 PF00067.22 GAP82511.1 - 3.3e-07 29.4 0.0 1.2e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 GAP82512.1 - 2.9e-09 36.8 0.1 0.0021 17.8 0.2 2.5 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.12 GAP82512.1 - 8.5e-08 32.2 0.1 2.2e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Brix PF04427.18 GAP82513.1 - 3.1e-50 171.0 0.0 4.1e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.13 GAP82513.1 - 0.17 11.9 16.9 0.24 11.3 16.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 GAP82513.1 - 0.44 10.4 9.9 0.65 9.8 9.9 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term PPL5 PF18168.1 GAP82513.1 - 1.1 8.5 3.8 1.8 7.7 3.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Tma16 PF11176.8 GAP82514.1 - 0.032 14.1 0.3 0.04 13.8 0.3 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 FAM180 PF15173.6 GAP82514.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 FAM180 family adh_short PF00106.25 GAP82516.1 - 2.2e-07 30.5 0.0 5.3e-07 29.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP82516.1 - 2.4e-05 24.0 0.1 0.00015 21.4 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_60s PF00428.19 GAP82516.1 - 0.14 12.8 3.0 0.29 11.7 3.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF676 PF05057.14 GAP82517.1 - 2.8e-08 33.6 0.0 5.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.12 GAP82517.1 - 8.2e-08 32.3 0.0 9.3e-06 25.7 0.0 2.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAP82517.1 - 5.8e-07 29.9 0.0 6.1e-05 23.3 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP82517.1 - 2.5e-05 24.7 0.0 0.00012 22.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 GAP82517.1 - 2.6e-05 25.0 0.0 0.00015 22.5 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family RNA_helicase PF00910.22 GAP82517.1 - 0.00041 20.7 0.0 0.0012 19.1 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA PF00004.29 GAP82517.1 - 0.0014 19.1 0.0 0.073 13.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Hydrolase_4 PF12146.8 GAP82517.1 - 0.0017 17.7 0.1 0.0087 15.3 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP82517.1 - 0.0078 15.9 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Torsin PF06309.11 GAP82517.1 - 0.039 14.1 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Torsin PGAP1 PF07819.13 GAP82517.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein AAA_5 PF07728.14 GAP82517.1 - 0.11 12.5 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 GAP82517.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 GAP82517.1 - 0.15 12.4 0.0 2.5 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAP82517.1 - 0.16 11.8 0.0 0.68 9.8 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 GAP82517.1 - 0.22 11.4 0.0 0.65 9.9 0.0 1.8 1 0 0 1 1 1 0 NTPase MeaB PF03308.16 GAP82517.1 - 0.22 10.5 0.0 0.41 9.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cutinase PF01083.22 GAP82518.1 - 1.5e-05 25.0 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 GAP82518.1 - 0.00051 20.7 0.0 0.00063 20.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 GAP82518.1 - 0.00076 19.1 0.0 0.0029 17.2 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF676 PF05057.14 GAP82519.1 - 3.5e-06 26.7 0.0 5.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.22 GAP82519.1 - 0.00035 20.6 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 Cutinase PGAP1 PF07819.13 GAP82519.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAP82519.1 - 0.0031 18.1 0.0 0.0036 17.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 GAP82519.1 - 0.026 14.4 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_8 PF06259.12 GAP82519.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Hydrolase_4 PF12146.8 GAP82519.1 - 0.13 11.5 0.1 0.54 9.5 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Binary_toxB PF03495.14 GAP82520.1 - 0.1 12.8 0.6 0.63 10.3 0.1 2.5 3 0 0 3 3 3 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain Excalibur PF05901.11 GAP82520.1 - 0.12 13.0 0.1 2.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Excalibur calcium-binding domain VCBS PF13517.6 GAP82520.1 - 0.18 12.4 0.1 0.18 12.4 0.1 3.8 4 1 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Amidohydro_1 PF01979.20 GAP82521.1 - 0.012 14.9 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family RabGAP-TBC PF00566.18 GAP82523.1 - 3.5e-34 118.3 0.1 7e-30 104.3 0.4 3.3 2 1 0 2 2 2 2 Rab-GTPase-TBC domain YqfQ PF14181.6 GAP82523.1 - 0.78 9.9 4.5 1.9 8.7 0.7 2.8 3 0 0 3 3 3 0 YqfQ-like protein UQ_con PF00179.26 GAP82524.1 - 7.7e-42 142.3 0.0 8.4e-42 142.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAP82524.1 - 6.4e-08 32.4 0.0 7.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAP82524.1 - 0.0092 16.3 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 RWD domain WH2 PF02205.20 GAP82527.1 - 2.7e-09 36.5 0.7 2.7e-09 36.5 0.7 2.3 3 0 0 3 3 3 1 WH2 motif ARTD15_N PF18084.1 GAP82528.1 - 0.089 13.0 0.2 0.29 11.4 0.1 1.9 2 1 0 2 2 2 0 ARTD15 N-terminal domain F-box PF00646.33 GAP82529.1 - 0.017 15.0 0.1 0.078 12.9 0.0 2.2 3 0 0 3 3 3 0 F-box domain COesterase PF00135.28 GAP82530.1 - 6e-08 32.0 0.0 6.8e-08 31.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Glutaredoxin PF00462.24 GAP82531.1 - 1.3e-12 47.8 0.0 3.2e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 GAP82531.1 - 0.00036 20.9 0.0 0.00074 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain POP1 PF06978.11 GAP82531.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 COesterase PF00135.28 GAP82532.1 - 2.1e-85 287.5 0.0 3.2e-85 287.0 0.0 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP82532.1 - 0.00013 21.9 3.1 0.0018 18.2 0.1 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP82532.1 - 0.026 14.0 0.9 0.049 13.1 0.9 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family tRNA-synt_2b PF00587.25 GAP82533.1 - 2e-30 106.1 0.0 1.6e-29 103.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAP82533.1 - 9.3e-06 25.7 0.0 4.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain CBF PF03914.17 GAP82534.1 - 2.4e-50 170.9 0.5 2.4e-50 170.9 0.5 2.6 3 1 0 3 3 3 1 CBF/Mak21 family BUD22 PF09073.10 GAP82534.1 - 0.00059 19.3 16.7 0.00059 19.3 16.7 3.5 3 1 1 4 4 4 1 BUD22 CDC27 PF09507.10 GAP82534.1 - 0.0013 18.2 17.9 0.0013 18.2 17.9 2.7 3 0 0 3 3 3 1 DNA polymerase subunit Cdc27 Mo25 PF08569.11 GAP82534.1 - 0.062 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Mo25-like Adaptin_N PF01602.20 GAP82534.1 - 0.077 11.5 1.5 1.3 7.5 0.1 2.1 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 GAP82534.1 - 0.083 12.9 1.6 0.17 11.9 0.1 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 4HBT PF03061.22 GAP82537.1 - 2.2e-11 43.9 0.5 5.4e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Thioesterase superfamily APS_kinase PF01583.20 GAP82538.1 - 4.3e-70 234.7 0.0 5.2e-70 234.4 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 GAP82538.1 - 7.9e-07 29.3 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAP82538.1 - 0.00093 19.7 0.0 0.0013 19.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAP82538.1 - 0.0023 17.4 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 GAP82538.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF463 PF04317.12 GAP82538.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 V-ATPase_C PF03223.15 GAP82540.1 - 1.2e-121 406.7 0.2 1.4e-121 406.4 0.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Terminase_3C PF17288.2 GAP82540.1 - 0.63 10.4 3.1 0.25 11.7 0.2 1.8 2 0 0 2 2 2 0 Terminase RNAseH like domain Cupin_2 PF07883.11 GAP82541.1 - 1.9e-10 40.3 0.0 3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain DMSP_lyase PF16867.5 GAP82541.1 - 0.013 15.1 0.1 0.017 14.8 0.1 1.1 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Cupin_1 PF00190.22 GAP82541.1 - 0.024 14.2 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_7 PF12973.7 GAP82541.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 ChrR Cupin-like domain Pirin PF02678.16 GAP82541.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Pirin Toxin_8 PF07365.12 GAP82542.1 - 0.18 12.0 1.0 0.6 10.3 1.0 1.9 1 0 0 1 1 1 0 Alpha conotoxin precursor AT_hook PF02178.19 GAP82542.1 - 3.5 7.8 17.6 12 6.2 3.7 3.2 2 0 0 2 2 2 0 AT hook motif F-box PF00646.33 GAP82543.1 - 4.9e-07 29.5 0.2 1.3e-06 28.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAP82543.1 - 7.6e-05 22.5 0.0 0.0004 20.2 0.0 2.3 1 0 0 1 1 1 1 F-box-like PEHE PF15275.6 GAP82543.1 - 0.043 14.4 0.5 0.092 13.4 0.5 1.6 1 0 0 1 1 1 0 PEHE domain FBPase PF00316.20 GAP82544.1 - 3e-14 52.9 0.0 5.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain TRM PF02005.16 GAP82547.1 - 3e-108 362.4 0.0 7.4e-95 318.3 0.0 2.4 2 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 GAP82547.1 - 0.00025 20.9 0.0 0.00067 19.5 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 GAP82547.1 - 0.0033 18.1 0.0 0.0087 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 GAP82547.1 - 0.0086 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 GAP82547.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase F-box PF00646.33 GAP82549.1 - 0.0067 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAP82549.1 - 0.059 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 F-box-like APH PF01636.23 GAP82550.1 - 7.3e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAP82550.1 - 0.00025 20.5 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 GAP82550.1 - 0.017 14.0 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 GAP82550.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 GAP82550.1 - 0.13 11.4 0.0 0.43 9.7 0.0 1.7 2 0 0 2 2 2 0 Fructosamine kinase SprT-like PF10263.9 GAP82551.1 - 0.051 13.4 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 SprT-like family DUF1996 PF09362.10 GAP82552.1 - 3.8e-33 115.5 0.1 4.6e-33 115.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FKBP_C PF00254.28 GAP82553.1 - 7.7e-26 90.3 0.1 9.5e-26 90.0 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MFS_1 PF07690.16 GAP82555.1 - 1.7e-26 93.0 27.8 1.7e-26 93.0 27.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3112 PF11309.8 GAP82556.1 - 3.1e-11 43.1 3.2 1.3e-06 28.1 0.1 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) adh_short PF00106.25 GAP82557.1 - 0.00085 18.8 0.0 0.0016 18.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP82557.1 - 0.065 12.8 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Metallophos PF00149.28 GAP82558.1 - 1.2e-37 130.4 0.5 2e-37 129.7 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAP82558.1 - 0.019 15.4 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 GAP82558.1 - 0.11 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Exo84_C PF16528.5 GAP82559.1 - 4.7e-74 248.6 0.8 4.7e-74 248.6 0.8 2.4 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 GAP82559.1 - 8.8e-17 61.0 1.8 3.4e-16 59.1 1.8 2.1 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 GAP82559.1 - 5.8e-05 23.2 0.2 0.0074 16.4 0.0 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4047 PF13256.6 GAP82559.1 - 0.067 13.4 1.8 0.15 12.3 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF677 PF05055.12 GAP82559.1 - 0.14 11.0 3.2 0.092 11.6 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF677) Ago_N_1 PF18351.1 GAP82559.1 - 0.19 12.2 0.8 1.5 9.3 0.1 2.5 2 1 1 3 3 3 0 Fungal Argonaute N-terminal domain Prominin PF05478.11 GAP82559.1 - 0.49 8.3 6.6 0.086 10.8 1.2 1.9 2 0 0 2 2 2 0 Prominin DUF4407 PF14362.6 GAP82559.1 - 0.65 9.3 7.5 2.3 7.5 6.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 GAP82559.1 - 2 9.0 17.6 0.17 12.4 7.6 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 GAP82559.1 - 2.4 8.5 9.4 0.43 10.9 3.4 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Seryl_tRNA_N PF02403.22 GAP82559.1 - 2.6 8.3 10.6 0.77 10.0 2.4 3.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MAS20 PF02064.15 GAP82560.1 - 3e-41 140.5 1.5 3.6e-41 140.3 1.5 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor AP-5_subunit_s1 PF15001.6 GAP82560.1 - 0.016 15.2 0.3 0.019 15.0 0.3 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 TetR_C_24 PF17932.1 GAP82560.1 - 0.23 11.7 2.6 0.99 9.7 2.0 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Radical_SAM PF04055.21 GAP82561.1 - 1.7e-23 83.8 0.0 5.4e-23 82.2 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 GAP82561.1 - 2.4e-23 82.2 0.0 5.1e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 GAP82561.1 - 2.4e-10 40.8 0.2 9e-09 35.7 0.2 2.7 1 1 0 1 1 1 1 Flavodoxin NOA36 PF06524.12 GAP82562.1 - 8.7 5.6 9.6 0.25 10.6 3.4 1.5 2 0 0 2 2 2 0 NOA36 protein Aminotran_1_2 PF00155.21 GAP82563.1 - 8.4e-53 179.8 0.1 9.3e-53 179.7 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Oxidored_FMN PF00724.20 GAP82563.1 - 0.038 13.3 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family SAP PF02037.27 GAP82564.1 - 9.6e-15 53.9 0.5 1.9e-14 53.0 0.5 1.4 1 0 0 1 1 1 1 SAP domain TFIIF_alpha PF05793.12 GAP82564.1 - 0.68 8.4 12.7 1.1 7.8 12.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GATase PF00117.28 GAP82565.1 - 2.1e-47 161.4 0.0 2.8e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 GAP82565.1 - 5.2e-47 158.9 0.0 1e-46 157.9 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 GAP82565.1 - 1.2e-05 25.2 0.3 0.0018 18.1 0.3 2.8 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 GAP82565.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family ETF PF01012.21 GAP82566.1 - 1.1e-42 146.0 1.3 1.3e-42 145.7 1.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.18 GAP82568.1 - 1.4e-31 108.9 0.2 2.8e-31 108.0 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.22 GAP82569.1 - 2.8e-31 107.1 0.1 7.2e-15 54.6 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAP82569.1 - 6.8e-05 22.9 0.0 0.041 14.0 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 GAP82569.1 - 0.003 17.1 0.0 2.4 7.7 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 GAP82569.1 - 0.021 15.1 0.0 6.8 6.9 0.0 3.2 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4783 PF16022.5 GAP82569.1 - 0.029 14.5 0.0 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) RRM_Rrp7 PF17799.1 GAP82569.1 - 0.068 13.0 0.0 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DbpA PF03880.15 GAP82569.1 - 0.11 12.5 0.3 12 5.9 0.0 3.0 3 0 0 3 3 3 0 DbpA RNA binding domain FXMRP1_C_core PF12235.8 GAP82569.1 - 1.4 9.5 18.2 0.27 11.9 11.2 2.8 3 0 0 3 3 3 0 Fragile X-related 1 protein core C terminal Flavodoxin_1 PF00258.25 GAP82570.1 - 1e-28 100.3 0.0 2.1e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 GAP82570.1 - 9.6e-25 87.4 0.0 4.3e-23 82.1 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GAP82570.1 - 1.7e-09 38.3 0.0 4.7e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FF PF01846.19 GAP82570.1 - 0.017 15.3 0.1 4.8 7.5 0.0 2.6 2 0 0 2 2 2 0 FF domain Flavodoxin_3 PF12641.7 GAP82570.1 - 0.053 13.2 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain Flavodoxin_5 PF12724.7 GAP82570.1 - 0.093 13.0 0.0 0.47 10.7 0.0 2.2 2 1 0 2 2 2 0 Flavodoxin domain LIP PF03583.14 GAP82572.1 - 0.035 13.4 0.0 0.84 8.9 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_4 PF08386.10 GAP82572.1 - 0.064 13.4 0.1 0.13 12.4 0.0 1.5 2 0 0 2 2 2 0 TAP-like protein Asp PF00026.23 GAP82573.1 - 3.3e-09 36.6 0.1 5.8e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease G_path_suppress PF15991.5 GAP82573.1 - 0.66 10.1 3.0 1.5 8.9 3.0 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor SKG6 PF08693.10 GAP82573.1 - 2.7 7.5 4.9 5.4 6.5 4.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F-box-like PF12937.7 GAP82574.1 - 2.4e-07 30.5 0.1 4.4e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP82574.1 - 5.7e-06 26.1 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain COPI_assoc PF08507.10 GAP82575.1 - 2e-34 118.5 5.0 2.6e-34 118.1 5.0 1.1 1 0 0 1 1 1 1 COPI associated protein TMEM72 PF16054.5 GAP82575.1 - 0.097 12.4 3.9 0.92 9.2 2.1 2.1 2 0 0 2 2 2 0 Transmembrane protein family 72 DUF3784 PF12650.7 GAP82575.1 - 0.16 12.2 9.3 0.27 11.4 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Cg6151-P PF10233.9 GAP82575.1 - 0.16 12.2 9.5 0.25 11.7 9.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P CRPA PF05745.11 GAP82575.1 - 0.3 11.1 2.3 0.52 10.3 2.3 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF2157 PF09925.9 GAP82575.1 - 1.9 8.3 4.6 2.8 7.7 4.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Ycf66_N PF07444.11 GAP82575.1 - 5.3 7.2 7.9 8.1 6.7 3.5 2.5 1 1 2 3 3 3 0 Ycf66 protein N-terminus GATA PF00320.27 GAP82577.1 - 1.7e-29 101.1 16.1 2.6e-15 55.7 2.8 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 GAP82577.1 - 1.7e-06 27.4 2.8 0.0084 15.6 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 GAP82577.1 - 2e-05 24.6 1.5 0.055 13.6 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain ArfGap PF01412.18 GAP82577.1 - 0.00021 21.3 1.7 0.24 11.5 0.2 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.11 GAP82577.1 - 0.0037 17.2 5.3 0.17 11.8 0.7 2.7 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 GAP82577.1 - 0.0071 16.5 5.6 0.46 10.7 0.7 2.6 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 GAP82577.1 - 0.022 14.8 13.7 0.74 9.9 0.5 3.4 2 1 1 3 3 3 0 Double zinc ribbon zf-RRN7 PF11781.8 GAP82577.1 - 0.029 14.1 0.5 0.029 14.1 0.5 3.1 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-Sec23_Sec24 PF04810.15 GAP82577.1 - 0.066 13.3 0.7 0.066 13.3 0.7 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger eIF-5_eIF-2B PF01873.17 GAP82577.1 - 0.11 12.3 5.1 2.6 7.9 0.5 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 A2L_zn_ribbon PF08792.10 GAP82577.1 - 0.19 11.5 6.1 8.6 6.2 0.2 4.2 4 0 0 4 4 4 0 A2L zinc ribbon domain FYVE PF01363.21 GAP82577.1 - 0.43 10.8 3.1 13 6.0 0.3 2.6 2 0 0 2 2 2 0 FYVE zinc finger zf-ribbon_3 PF13248.6 GAP82577.1 - 1.7 8.2 11.4 31 4.1 0.4 4.5 4 0 0 4 4 4 0 zinc-ribbon domain Ribosomal_L32p PF01783.23 GAP82577.1 - 5.1 7.4 10.5 4.9 7.5 2.0 3.9 2 2 0 2 2 2 0 Ribosomal L32p protein family ADK_lid PF05191.14 GAP82577.1 - 5.4 7.1 6.6 4.2 7.4 0.3 3.4 3 0 0 3 3 3 0 Adenylate kinase, active site lid Rubredoxin_2 PF18073.1 GAP82577.1 - 5.5 6.8 10.0 29 4.5 0.1 4.6 4 0 0 4 4 4 0 Rubredoxin metal binding domain Acetyltransf_1 PF00583.25 GAP82578.1 - 1.2e-06 28.7 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP82578.1 - 0.1 13.0 0.0 0.14 12.6 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP82578.1 - 0.12 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein AAA_6 PF12774.7 GAP82579.1 - 6.1e-126 419.8 0.6 3.2e-125 417.4 0.0 2.7 4 0 0 4 4 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 GAP82579.1 - 8.9e-123 410.9 15.2 8.9e-123 410.9 15.2 4.4 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 GAP82579.1 - 3.3e-114 382.1 9.4 3.3e-114 382.1 9.4 5.6 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 GAP82579.1 - 4.1e-74 248.4 0.5 4.1e-74 248.4 0.5 4.0 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 GAP82579.1 - 1.5e-66 224.4 0.0 7.7e-66 222.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 GAP82579.1 - 3.4e-42 144.0 0.0 1e-35 122.9 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 GAP82579.1 - 1.7e-39 135.8 8.8 1.7e-39 135.8 8.8 2.3 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 GAP82579.1 - 5.6e-33 113.6 0.1 1.3e-27 96.2 0.0 4.7 4 0 0 4 4 3 2 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 GAP82579.1 - 2.9e-30 105.1 0.0 1.7e-11 44.3 0.0 6.5 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 GAP82579.1 - 4.3e-28 98.2 0.0 1.2e-27 96.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 GAP82579.1 - 6.4e-15 55.6 0.3 0.0077 16.5 0.0 5.9 5 0 0 5 5 4 3 AAA domain Dynein_AAA_lid PF17852.1 GAP82579.1 - 3.3e-14 53.1 0.0 1.2e-13 51.2 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 GAP82579.1 - 1.9e-13 51.0 0.0 0.0018 18.7 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP82579.1 - 8.4e-10 39.3 3.1 1.8 8.9 0.0 7.5 7 0 0 7 7 5 2 AAA ATPase domain AAA_33 PF13671.6 GAP82579.1 - 8.4e-10 39.0 1.0 0.3 11.2 0.0 5.2 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 GAP82579.1 - 3.2e-09 37.4 0.1 0.094 13.3 0.0 5.2 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 GAP82579.1 - 1.1e-05 24.7 0.0 0.018 14.1 0.0 3.5 4 0 0 4 4 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 GAP82579.1 - 7.4e-05 22.2 1.1 0.68 9.3 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 GAP82579.1 - 8.2e-05 22.3 0.1 2.3 8.0 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 GAP82579.1 - 0.00016 21.9 0.0 0.00088 19.4 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain ABC_tran PF00005.27 GAP82579.1 - 0.00019 22.0 0.1 4.2 7.9 0.0 4.7 3 0 0 3 3 3 1 ABC transporter AAA_30 PF13604.6 GAP82579.1 - 0.00047 19.9 0.6 39 3.9 0.0 4.9 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 GAP82579.1 - 0.0011 19.3 3.2 0.28 11.5 0.0 4.9 5 0 0 5 5 4 1 AAA domain IstB_IS21 PF01695.17 GAP82579.1 - 0.0019 17.9 0.4 0.73 9.5 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 GAP82579.1 - 0.0066 16.2 3.2 12 5.6 0.0 5.0 6 0 0 6 6 5 0 AAA domain FtsK_SpoIIIE PF01580.18 GAP82579.1 - 0.0072 15.7 4.2 2.4 7.5 0.0 4.7 4 0 0 4 4 3 1 FtsK/SpoIIIE family Phage_GP20 PF06810.11 GAP82579.1 - 0.0073 16.1 13.7 0.83 9.4 7.7 3.5 2 0 0 2 2 2 2 Phage minor structural protein GP20 AAA_25 PF13481.6 GAP82579.1 - 0.0078 15.8 5.6 0.24 10.9 0.0 3.8 4 0 0 4 4 2 1 AAA domain RNA_helicase PF00910.22 GAP82579.1 - 0.011 16.1 0.2 28 5.2 0.0 4.6 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 GAP82579.1 - 0.049 13.6 0.4 6.6 6.6 0.0 3.7 5 0 0 5 5 3 0 Rad17 P-loop domain DUF4482 PF14818.6 GAP82579.1 - 0.37 11.7 8.9 20 6.0 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) UCH PF00443.29 GAP82579.1 - 1.2 8.6 4.4 17 4.8 0.1 3.8 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase DUF1843 PF08898.10 GAP82579.1 - 2.6 8.6 6.1 27 5.4 5.0 3.4 2 0 0 2 2 1 0 Domain of unknown function (DUF1843) NACHT PF05729.12 GAP82579.1 - 3.8 7.4 6.0 31 4.4 0.0 4.2 4 0 0 4 4 3 0 NACHT domain ERM PF00769.19 GAP82579.1 - 4.3 7.1 37.4 0.21 11.4 13.7 4.1 4 0 0 4 4 3 0 Ezrin/radixin/moesin family XhlA PF10779.9 GAP82579.1 - 4.8 7.5 5.6 2.7 8.3 0.3 3.5 2 0 0 2 2 1 0 Haemolysin XhlA DUF2205 PF10224.9 GAP82579.1 - 7.1 6.7 10.2 1.5 8.9 1.5 4.2 3 0 0 3 3 2 0 Short coiled-coil protein Prefoldin PF02996.17 GAP82579.1 - 7.1 6.6 17.2 5.9 6.8 0.6 5.7 4 0 0 4 4 4 0 Prefoldin subunit FAR1 PF03101.15 GAP82580.1 - 6.9e-05 23.5 0.1 0.00016 22.3 0.1 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain CdvA PF18822.1 GAP82580.1 - 0.035 13.9 3.3 0.065 13.1 3.3 1.4 1 0 0 1 1 1 0 CdvA-like coiled-coil domain COG2 PF06148.11 GAP82580.1 - 0.11 12.6 1.9 0.65 10.1 1.9 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YtxH PF12732.7 GAP82580.1 - 0.92 10.1 2.9 2.1 8.9 2.9 1.5 1 0 0 1 1 1 0 YtxH-like protein UBM PF14377.6 GAP82581.1 - 0.033 13.7 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin binding region Transpos_assoc PF13963.6 GAP82582.1 - 0.11 12.8 0.8 5.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Transposase-associated domain Amidohydro_3 PF07969.11 GAP82583.1 - 3.2e-23 82.9 4.3 3.8e-23 82.7 4.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 GAP82583.1 - 9.1e-06 25.2 0.0 1.2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Acetyltransf_1 PF00583.25 GAP82584.1 - 8.6e-05 22.8 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family CENP-T_C PF15511.6 GAP82585.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 GAP82585.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Svf1_C PF17187.4 GAP82586.1 - 2.4e-56 190.1 0.0 4.1e-56 189.3 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 GAP82586.1 - 4e-55 186.3 0.0 7.9e-55 185.4 0.0 1.5 2 0 0 2 2 2 1 Svf1-like N-terminal lipocalin domain KH_4 PF13083.6 GAP82586.1 - 0.021 14.7 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 KH domain DUF4873 PF16170.5 GAP82586.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4873) Ribosomal_L11 PF00298.19 GAP82587.1 - 9.9e-27 93.2 0.2 2e-26 92.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 GAP82587.1 - 1.1e-25 89.3 0.1 1.8e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 GAP82589.1 - 5.1e-48 163.7 0.0 1.4e-47 162.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP82589.1 - 3.5e-21 75.7 0.0 6.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP82589.1 - 0.0035 17.3 0.0 0.009 16.0 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAP82589.1 - 0.023 13.7 0.0 0.052 12.5 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Cpn10 PF00166.21 GAP82590.1 - 2.2e-29 101.4 0.0 2.5e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Glyco_hydro_61 PF03443.14 GAP82591.1 - 1.5e-51 175.3 0.0 2.1e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cys_Met_Meta_PP PF01053.20 GAP82593.1 - 3.8e-138 460.2 0.0 4.4e-138 460.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAP82593.1 - 5e-09 35.8 0.1 7.7e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAP82593.1 - 1.1e-05 24.6 0.6 1.8e-05 23.9 0.3 1.4 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAP82593.1 - 2.9e-05 23.5 0.4 5.6e-05 22.6 0.4 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GAP82593.1 - 0.027 13.8 0.5 0.04 13.2 0.5 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase 2-Hacid_dh PF00389.30 GAP82593.1 - 0.048 13.3 0.1 0.058 13.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain HTH_AraC PF00165.23 GAP82593.1 - 0.18 12.0 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family ABC_tran PF00005.27 GAP82594.1 - 9.4e-50 168.7 0.1 1.4e-27 96.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAP82594.1 - 5.2e-44 150.9 16.8 9.6e-27 94.3 5.7 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 GAP82594.1 - 8.9e-09 35.1 5.1 0.0093 15.4 2.2 4.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAP82594.1 - 2.9e-07 31.2 1.4 0.00015 22.4 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAP82594.1 - 4.3e-07 29.6 2.9 0.0071 16.1 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 GAP82594.1 - 6.9e-07 29.4 1.3 0.4 10.4 0.5 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAP82594.1 - 1.3e-05 24.9 0.0 0.22 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAP82594.1 - 1.8e-05 24.7 0.4 0.13 12.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 GAP82594.1 - 2.8e-05 24.3 0.9 0.14 12.2 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 GAP82594.1 - 4.9e-05 23.8 0.1 0.081 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 GAP82594.1 - 0.00015 21.9 0.3 0.023 14.8 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GAP82594.1 - 0.00081 19.7 2.3 0.4 10.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 GAP82594.1 - 0.00089 19.1 0.0 1.2 8.8 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 GAP82594.1 - 0.0012 19.0 4.3 0.013 15.6 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 GAP82594.1 - 0.0012 17.9 0.5 0.99 8.4 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 GAP82594.1 - 0.0016 17.8 0.5 0.57 9.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.6 GAP82594.1 - 0.0075 16.5 0.1 5 7.4 0.1 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 GAP82594.1 - 0.0089 16.2 0.0 3 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAP82594.1 - 0.0089 15.2 2.7 3.7 6.7 0.1 3.8 3 1 0 3 3 3 1 NB-ARC domain MeaB PF03308.16 GAP82594.1 - 0.013 14.5 0.7 1.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 GAP82594.1 - 0.014 15.3 1.7 2.4 8.1 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 GAP82594.1 - 0.022 14.5 0.2 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 GAP82594.1 - 0.044 13.7 0.1 1.5 8.7 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Septin PF00735.18 GAP82594.1 - 0.047 13.0 0.1 5.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.17 GAP82594.1 - 0.05 13.4 0.1 11 5.8 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein cobW PF02492.19 GAP82594.1 - 0.056 13.0 4.2 2.9 7.4 1.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 GAP82594.1 - 0.06 13.0 0.5 5 6.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAP82594.1 - 0.087 12.7 1.1 17 5.3 0.2 2.8 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 GAP82594.1 - 0.09 12.5 0.3 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAP82594.1 - 0.15 12.6 0.1 27 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAP82594.1 - 0.18 11.3 0.6 2 7.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 GAP82594.1 - 0.21 11.8 0.5 8.2 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 GAP82594.1 - 0.27 10.7 3.6 0.42 10.0 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein TrwB_AAD_bind PF10412.9 GAP82594.1 - 2.2 7.1 4.6 7.9 5.3 0.1 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain CUE PF02845.16 GAP82595.1 - 0.2 11.4 0.2 7.9 6.3 0.1 2.6 2 0 0 2 2 2 0 CUE domain SPX PF03105.19 GAP82595.1 - 6.8 6.5 10.8 12 5.7 10.8 1.3 1 0 0 1 1 1 0 SPX domain Rit1_C PF17184.4 GAP82597.1 - 9e-19 68.0 0.0 1.3e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 GAP82597.1 - 3e-12 46.8 0.0 8.1e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Rit1 DUSP-like domain adh_short PF00106.25 GAP82598.1 - 4.3e-84 280.8 11.7 1.6e-43 148.4 0.4 3.0 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP82598.1 - 4.1e-65 219.6 6.7 4.7e-33 114.7 0.3 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 GAP82598.1 - 3e-32 110.8 0.0 5.8e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 GAP82598.1 - 4.4e-29 101.7 4.5 4.2e-15 56.1 0.8 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 GAP82598.1 - 0.0012 18.2 0.6 0.013 14.8 0.2 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Caf4 PF11615.8 GAP82598.1 - 0.18 11.8 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 CCR4-associated factor 4 Epimerase PF01370.21 GAP82598.1 - 0.18 11.2 4.3 1.6 8.1 0.1 2.8 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family PglL_A PF15864.5 GAP82598.1 - 2.2 8.1 8.0 5.5 6.8 1.0 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase 3HCDH_N PF02737.18 GAP82598.1 - 2.6 7.9 6.8 3.3 7.6 0.9 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECM11 PF15463.6 GAP82599.1 - 3.8e-41 140.8 0.6 3.8e-41 140.8 0.6 2.4 3 0 0 3 3 3 1 Extracellular mutant protein 11 Acetyltransf_1 PF00583.25 GAP82600.1 - 0.013 15.8 0.0 0.036 14.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family OrfB_IS605 PF01385.19 GAP82600.1 - 0.082 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Probable transposase Glyco_transf_90 PF05686.12 GAP82601.1 - 0.068 12.1 0.0 4.1 6.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 90 CENP-B_dimeris PF09026.10 GAP82601.1 - 0.14 12.6 5.9 0.23 11.8 5.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 GAP82601.1 - 0.3 10.8 6.4 0.2 11.4 1.4 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAP82601.1 - 3 7.1 5.6 4.4 6.5 5.6 1.1 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 GAP82602.1 - 4e-42 144.4 51.6 7.6e-42 143.5 51.6 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldolase_II PF00596.21 GAP82603.1 - 0.00055 19.9 0.1 0.00074 19.5 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Utp21 PF04192.12 GAP82604.1 - 1e-81 273.9 0.0 1.5e-81 273.4 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 GAP82604.1 - 2.7e-17 62.8 16.9 9.4e-05 23.1 0.3 8.8 9 1 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP82604.1 - 1.2e-12 48.0 0.0 5.1e-05 23.5 0.0 6.3 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAP82604.1 - 0.00024 19.7 0.0 0.00043 18.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 GAP82604.1 - 0.0011 17.7 0.2 3.1 6.3 0.0 4.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAP82604.1 - 0.0055 15.5 0.0 0.65 8.7 0.0 2.4 1 1 0 2 2 2 2 Nup133 N terminal like His_Phos_2 PF00328.22 GAP82605.1 - 2.6e-109 366.1 0.0 6.2e-109 364.8 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 GAP82605.1 - 1.2e-35 121.5 0.0 2.7e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 GAP82605.1 - 1.3e-06 28.1 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain FGGY_C PF02782.16 GAP82607.1 - 7.9e-14 51.8 0.1 1e-13 51.5 0.1 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MOSC PF03473.17 GAP82608.1 - 1.7e-30 105.7 0.4 1e-29 103.2 0.4 1.8 1 1 0 1 1 1 1 MOSC domain GSK-3_bind PF05350.12 GAP82608.1 - 0.043 13.1 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding MOSC_N PF03476.16 GAP82609.1 - 1.3e-10 41.2 0.0 4.9e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Glyco_hydro_76 PF03663.14 GAP82610.1 - 4e-35 122.0 15.9 1.7e-34 120.0 15.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 GAP82610.1 - 5.8e-06 25.6 1.0 0.0041 16.3 0.0 2.5 3 0 0 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 GAP82610.1 - 0.00098 18.7 0.2 0.16 11.5 0.0 2.6 2 1 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 GAP82610.1 - 0.0028 16.2 0.1 0.67 8.4 0.0 2.2 1 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 TFCD_C PF12612.8 GAP82611.1 - 5.1e-25 88.4 0.1 3.3e-24 85.8 0.1 2.5 1 1 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 GAP82611.1 - 0.074 13.3 5.5 1.1 9.7 0.0 5.3 6 0 0 6 6 6 0 HEAT repeat HEAT_2 PF13646.6 GAP82611.1 - 0.3 11.5 10.4 0.66 10.4 0.1 5.4 5 1 2 7 7 7 0 HEAT repeats RNA_pol_Rpb5_C PF01191.19 GAP82614.1 - 2.6e-33 113.7 0.4 5.6e-33 112.6 0.3 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 GAP82614.1 - 7.8e-26 90.5 0.0 1.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 GAP82614.1 - 0.0048 16.9 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 Restriction endonuclease MTS PF05175.14 GAP82615.1 - 4.6e-06 26.3 0.2 0.033 13.7 0.5 3.1 2 1 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 GAP82615.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 GAP82615.1 - 0.00027 20.7 0.6 0.042 13.5 0.6 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 GAP82615.1 - 0.0027 18.4 0.9 0.038 14.7 1.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAP82615.1 - 0.0056 16.1 0.2 0.01 15.3 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.16 GAP82615.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase EzrA PF06160.12 GAP82616.1 - 6.7e-06 24.6 15.5 6.7e-06 24.6 15.5 3.0 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 GAP82616.1 - 0.0002 21.5 1.7 0.0002 21.5 1.7 6.3 3 2 4 7 7 7 2 ABC transporter C-terminal domain Hemagglutinin PF00509.18 GAP82616.1 - 2 6.7 8.7 2.1 6.7 1.1 2.2 1 1 1 2 2 2 0 Haemagglutinin APG6_N PF17675.1 GAP82616.1 - 4.7 7.7 53.5 0.28 11.7 21.3 4.9 2 1 1 3 3 3 0 Apg6 coiled-coil region GTP1_OBG PF01018.22 GAP82618.1 - 1.2e-39 135.4 1.8 3.2e-29 101.5 4.7 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 GAP82618.1 - 3.5e-24 85.1 0.0 2e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAP82618.1 - 7e-08 32.1 0.0 2.8e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 GAP82618.1 - 0.0056 15.7 0.1 0.45 9.5 0.0 2.5 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 GAP82618.1 - 0.036 14.6 0.0 0.13 12.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Arf PF00025.21 GAP82618.1 - 0.066 12.7 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 GAP82618.1 - 0.076 13.6 0.4 0.59 10.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAP82618.1 - 0.17 12.0 0.1 2 8.5 0.0 2.6 2 1 0 2 2 2 0 Dynamin family Dynamin_N PF00350.23 GAP82619.1 - 3.6e-31 108.5 0.6 6.7e-30 104.4 0.1 2.4 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 GAP82619.1 - 3.9e-22 78.8 0.0 3.4e-18 65.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 GAP82619.1 - 2.9e-05 24.1 0.1 0.00016 21.7 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 GAP82619.1 - 0.00023 21.2 0.7 0.0014 18.7 0.1 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain Importin_rep_6 PF18829.1 GAP82619.1 - 0.11 12.7 4.1 0.52 10.5 4.1 2.2 1 0 0 1 1 1 0 Importin repeat 6 FeoB_N PF02421.18 GAP82619.1 - 0.12 11.9 0.1 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 GAP82619.1 - 0.16 12.2 0.1 0.75 10.0 0.0 2.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DNA_pol_phi PF04931.13 GAP82619.1 - 1.5 6.8 6.7 2.4 6.2 6.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GAP82619.1 - 2.1 7.6 4.7 3.1 7.0 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein Peptidase_S8 PF00082.22 GAP82620.1 - 5.8e-19 68.4 14.2 6.4e-19 68.3 14.2 1.0 1 0 0 1 1 1 1 Subtilase family Aldolase_II PF00596.21 GAP82621.1 - 2.6e-47 161.2 0.0 3.2e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CorA PF01544.18 GAP82622.1 - 0.0097 15.3 5.2 0.012 15.0 3.9 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4866 PF16160.5 GAP82622.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4866) Methyltr_RsmB-F PF01189.17 GAP82623.1 - 3.6e-30 105.1 0.0 1e-23 84.0 0.0 3.1 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 GAP82623.1 - 0.022 14.9 0.0 0.062 13.4 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Cupin_5 PF06172.11 GAP82624.1 - 5.3e-36 123.9 0.0 6.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) GTP_EFTU PF00009.27 GAP82625.1 - 7.5e-55 185.5 0.0 1.2e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 GAP82625.1 - 8.9e-19 67.4 0.0 2.8e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 GAP82625.1 - 8.6e-12 44.9 0.0 7e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAP82625.1 - 5.6e-05 23.5 0.0 0.0002 21.7 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAP82625.1 - 0.0007 19.4 0.0 0.0041 16.9 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain Vps5 PF09325.10 GAP82626.1 - 2.1e-14 53.6 1.7 3.2e-14 53.0 1.7 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 GAP82626.1 - 3.2e-07 30.3 0.0 8.1e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 PX domain NST1 PF13945.6 GAP82626.1 - 0.0094 16.1 1.9 0.017 15.2 1.9 1.4 1 0 0 1 1 1 1 Salt tolerance down-regulator MerR-DNA-bind PF09278.11 GAP82626.1 - 1.3 9.6 4.4 0.41 11.2 1.0 2.0 2 0 0 2 2 2 0 MerR, DNA binding CorA PF01544.18 GAP82627.1 - 0.00055 19.3 3.0 0.0013 18.1 3.0 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ADH_N PF08240.12 GAP82628.1 - 6.8e-27 93.5 1.5 1.5e-26 92.4 1.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP82628.1 - 2.5e-14 53.4 0.1 4.8e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAP82628.1 - 4e-07 29.7 1.0 0.00065 19.3 0.1 2.5 3 0 0 3 3 3 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAP82628.1 - 0.009 17.1 0.0 0.027 15.5 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 GAP82628.1 - 0.016 14.6 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 GAP82628.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 GAP82628.1 - 0.079 12.5 0.8 0.17 11.4 0.2 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 GAP82628.1 - 0.29 10.4 4.3 0.055 12.8 0.7 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAA_hydrolase PF01557.18 GAP82629.1 - 3.6e-21 75.8 0.0 4.9e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MitMem_reg PF13012.6 GAP82630.1 - 7.5e-12 45.7 0.0 1.7e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAP82630.1 - 2.5e-08 33.9 0.0 4.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Glyco_hydro_28 PF00295.17 GAP82632.1 - 3.7e-51 174.1 1.5 5.3e-51 173.6 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short_C2 PF13561.6 GAP82632.1 - 9.3e-45 153.0 1.5 1e-44 152.8 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP82632.1 - 2.2e-28 99.1 0.0 3.8e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Beta_helix PF13229.6 GAP82632.1 - 0.14 12.0 1.3 0.6 9.9 1.0 2.1 1 1 0 1 1 1 0 Right handed beta helix region Thymosin PF01290.20 GAP82633.1 - 0.12 12.2 1.1 0.27 11.0 1.1 1.6 1 0 0 1 1 1 0 Thymosin beta-4 family Trm112p PF03966.16 GAP82634.1 - 0.11 13.1 0.0 0.12 13.0 0.0 1.1 1 0 0 1 1 1 0 Trm112p-like protein DUF572 PF04502.13 GAP82635.1 - 9.4 5.7 41.4 1.6 8.2 20.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) IU_nuc_hydro PF01156.19 GAP82636.1 - 1.6e-54 185.6 0.0 2.5e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Alpha-amylase PF00128.24 GAP82638.1 - 9.9e-58 196.3 0.1 1.3e-57 195.9 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 GAP82638.1 - 1.6e-33 114.5 0.2 3.4e-33 113.4 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 GAP82638.1 - 7.7e-17 61.4 0.1 1.7e-16 60.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 GAP82638.1 - 0.05 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DSBA PF01323.20 GAP82639.1 - 1.3e-05 25.1 0.0 1.5e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Fungal_trans PF04082.18 GAP82640.1 - 8e-14 51.3 0.3 1.6e-13 50.3 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP82640.1 - 5.2e-08 32.9 11.1 8.3e-08 32.2 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AviRa PF11599.8 GAP82640.1 - 0.037 13.5 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Cu-oxidase_3 PF07732.15 GAP82641.1 - 1.1e-43 148.0 6.9 6.3e-42 142.3 0.7 3.8 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAP82641.1 - 1.4e-35 122.1 1.7 1.5e-32 112.2 0.1 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 GAP82641.1 - 1.3e-28 100.2 0.0 1.7e-27 96.5 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Monooxygenase_B PF04744.12 GAP82641.1 - 0.31 9.8 0.5 0.52 9.1 0.5 1.2 1 0 0 1 1 1 0 Monooxygenase subunit B protein FPN1 PF06963.12 GAP82642.1 - 7.7e-79 265.3 14.9 4.4e-59 200.2 4.6 2.1 2 0 0 2 2 2 2 Ferroportin1 (FPN1) FSH1 PF03959.13 GAP82643.1 - 3.9e-29 101.8 0.0 4.8e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 GAP82643.1 - 1.3e-05 25.9 9.6 0.0095 16.6 2.9 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_M19 PF01244.21 GAP82644.1 - 1.3e-51 175.7 0.0 1.4e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) TPR_12 PF13424.6 GAP82647.1 - 3.7e-18 65.6 4.1 5.3e-06 26.6 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAP82647.1 - 6e-17 60.9 5.9 0.00044 20.0 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAP82647.1 - 3.4e-11 42.4 0.2 0.55 10.5 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAP82647.1 - 1.2e-10 40.7 0.3 0.51 10.5 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat AAA_22 PF13401.6 GAP82647.1 - 1.6e-07 31.7 0.0 7.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ANAPC3 PF12895.7 GAP82647.1 - 2.5e-06 27.6 0.3 0.85 9.9 0.0 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAP82647.1 - 6.5e-06 26.7 0.5 6 7.6 0.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAP82647.1 - 1.3e-05 25.6 1.0 0.017 15.6 0.1 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP82647.1 - 0.00014 21.8 0.0 9.7 6.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF900 PF05990.12 GAP82647.1 - 0.00023 20.8 0.0 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) NB-ARC PF00931.22 GAP82647.1 - 0.00023 20.4 0.0 0.00045 19.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_MalT PF17874.1 GAP82647.1 - 0.00029 20.3 1.5 0.057 12.8 0.1 3.0 2 1 1 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 GAP82647.1 - 0.00096 19.8 0.6 3 8.9 0.6 4.3 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 GAP82647.1 - 0.0011 19.3 1.0 12 6.3 0.2 4.6 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAP82647.1 - 0.002 18.7 0.0 15 6.5 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF676 PF05057.14 GAP82647.1 - 0.0043 16.6 0.1 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAP82647.1 - 0.0045 16.7 0.0 0.026 14.3 0.0 2.1 1 1 1 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 GAP82647.1 - 0.0047 16.2 0.0 0.026 13.8 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 NACHT PF05729.12 GAP82647.1 - 0.015 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 GAP82647.1 - 0.034 14.5 0.0 0.095 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 GAP82647.1 - 0.071 13.0 0.0 1.7 8.5 0.0 2.7 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 GAP82647.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_4 PF07721.14 GAP82647.1 - 1.3 9.9 4.8 2.4 9.0 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_10 PF00331.20 GAP82648.1 - 4.5e-40 137.7 0.0 5.3e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 InPase PF18823.1 GAP82648.1 - 0.087 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Inorganic Pyrophosphatase Solute_trans_a PF03619.16 GAP82649.1 - 1.7e-84 283.5 24.6 2e-84 283.3 24.6 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Isochorismatase PF00857.20 GAP82650.1 - 1.1e-21 77.8 0.0 1.4e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Myb_DNA-binding PF00249.31 GAP82651.1 - 2.7e-35 120.3 14.0 3e-12 46.5 1.2 4.0 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP82651.1 - 2.1e-31 107.9 8.0 8.9e-14 51.5 0.3 3.9 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAP82651.1 - 6.4e-07 29.2 1.3 0.0043 16.9 0.1 3.5 3 0 0 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 GAP82651.1 - 4.6e-06 26.6 0.8 0.13 12.3 0.1 3.6 2 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 GAP82651.1 - 0.0001 22.4 5.2 0.00075 19.6 1.1 2.9 3 0 0 3 3 3 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 GAP82651.1 - 0.00031 20.8 5.2 0.65 10.1 5.2 3.0 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 GAP82651.1 - 0.16 12.2 4.2 0.33 11.2 0.5 3.3 5 1 0 5 5 5 0 Rap1 Myb domain Myb_DNA-bind_5 PF13873.6 GAP82651.1 - 0.3 11.2 4.7 2.4 8.3 0.2 3.3 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain adh_short PF00106.25 GAP82652.1 - 8.3e-30 103.7 0.0 8e-25 87.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP82652.1 - 3.2e-24 85.8 0.0 1.4e-17 64.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAP82652.1 - 3.1e-05 23.5 0.0 4.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAP82652.1 - 0.0096 15.8 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 KR domain ABM PF03992.16 GAP82653.1 - 4.7e-05 23.4 0.5 8.2e-05 22.6 0.5 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase GFA PF04828.14 GAP82654.1 - 3.9e-19 68.8 1.8 5e-19 68.4 1.8 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 GAP82654.1 - 1.9 8.5 6.5 3 7.9 0.1 3.1 3 0 0 3 3 3 0 Nudix N-terminal MFS_1 PF07690.16 GAP82656.1 - 4.1e-38 131.2 78.1 1.5e-35 122.8 53.5 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2784 PF10861.8 GAP82656.1 - 0.78 9.8 11.1 8 6.5 4.2 3.1 2 0 0 2 2 2 0 Protein of Unknown function (DUF2784) WSC PF01822.19 GAP82657.1 - 1.6e-10 41.0 8.9 5.4e-10 39.3 8.9 1.9 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 GAP82657.1 - 0.00063 19.1 0.9 0.0017 17.7 0.9 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 GAP82657.1 - 0.0015 18.6 13.9 0.0037 17.4 13.9 1.6 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.6 GAP82657.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Amnionless PF14828.6 GAP82657.1 - 0.026 13.4 0.1 0.037 12.9 0.1 1.4 1 0 0 1 1 1 0 Amnionless Cuticle_2 PF08184.11 GAP82657.1 - 0.035 14.1 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 Cuticle protein 7 isoform family VSP PF03302.13 GAP82657.1 - 0.055 12.3 18.1 0.08 11.8 18.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4366 PF14283.6 GAP82657.1 - 0.093 12.8 0.5 0.28 11.2 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4231 PF14015.6 GAP82657.1 - 0.18 12.3 2.0 0.26 11.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4064 PF13273.6 GAP82657.1 - 0.51 10.6 6.6 0.043 14.1 1.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) COesterase PF00135.28 GAP82658.1 - 5.5e-08 32.1 0.9 1.2e-07 31.0 0.9 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP82658.1 - 2.8e-05 24.1 7.1 5.2e-05 23.2 7.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP82658.1 - 8.6e-05 21.6 0.0 0.00015 20.8 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 GAP82658.1 - 0.89 8.8 3.0 2.5 7.3 3.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Spt20 PF12090.8 GAP82659.1 - 0.0089 15.7 5.4 0.015 15.0 5.4 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 GAP82659.1 - 0.044 13.8 5.9 0.094 12.7 5.9 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 GAP82659.1 - 0.062 12.5 2.2 0.11 11.6 2.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Macoilin PF09726.9 GAP82659.1 - 0.16 10.5 1.4 0.29 9.6 1.4 1.4 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 GAP82659.1 - 8.3 5.7 7.1 19 4.5 7.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Filament PF00038.21 GAP82660.1 - 0.0001 22.0 58.6 0.0014 18.2 16.9 4.3 4 1 0 4 4 4 2 Intermediate filament protein AAA_13 PF13166.6 GAP82660.1 - 0.0038 16.0 6.5 0.0038 16.0 6.5 5.2 2 1 2 5 5 5 1 AAA domain TMF_DNA_bd PF12329.8 GAP82660.1 - 0.097 12.7 0.1 0.097 12.7 0.1 7.6 8 2 0 9 9 9 0 TATA element modulatory factor 1 DNA binding VGPC1_C PF16799.5 GAP82660.1 - 0.29 11.1 10.1 0.033 14.2 4.8 2.3 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 HALZ PF02183.18 GAP82660.1 - 0.55 10.5 34.4 0.75 10.1 1.9 7.6 6 1 1 7 7 7 0 Homeobox associated leucine zipper RSN1_7TM PF02714.15 GAP82661.1 - 9.8e-83 277.6 26.5 9.8e-83 277.6 26.5 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAP82661.1 - 1.8e-46 157.8 2.1 1.8e-46 157.8 2.1 2.9 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAP82661.1 - 1.2e-35 123.4 0.0 1.7e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 GAP82661.1 - 1.4e-32 111.7 0.1 3.5e-32 110.4 0.1 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 GAP82661.1 - 0.11 12.3 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) kleA_kleC PF17383.2 GAP82661.1 - 0.21 11.9 1.1 1.7 9.0 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A E1_DerP2_DerF2 PF02221.15 GAP82662.1 - 1.3e-27 96.9 0.8 1.6e-27 96.6 0.8 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 GAP82662.1 - 0.00072 19.9 0.0 0.0018 18.7 0.0 1.7 1 1 0 1 1 1 1 ML-like domain Asparaginase PF00710.20 GAP82663.1 - 4.7e-35 120.9 0.0 6.3e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 GAP82663.1 - 2.8e-15 56.5 0.2 4.7e-15 55.8 0.2 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain ATP-synt_F PF01990.17 GAP82664.1 - 1.1e-33 115.3 0.1 1.3e-33 115.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 GAP82664.1 - 0.043 13.0 0.0 0.043 13.0 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF2418 PF10332.9 GAP82665.1 - 2e-35 121.2 0.1 6.1e-35 119.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) CHCH PF06747.13 GAP82667.1 - 0.00012 22.1 6.5 0.00014 21.9 5.2 1.7 1 1 1 2 2 2 2 CHCH domain Trypan_glycop_C PF10659.9 GAP82667.1 - 0.0025 18.2 3.6 0.0028 18.0 3.6 1.1 1 0 0 1 1 1 1 Trypanosome variant surface glycoprotein C-terminal domain GCK PF07802.11 GAP82667.1 - 0.014 15.8 0.8 0.029 14.8 0.8 1.6 1 1 0 1 1 1 0 GCK domain CX9C PF16860.5 GAP82667.1 - 0.036 14.1 3.4 0.05 13.6 3.4 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NPBW PF15180.6 GAP82667.1 - 0.051 13.4 0.0 0.056 13.3 0.0 1.1 1 0 0 1 1 1 0 Neuropeptides B and W Glyco_hydro_44 PF12891.7 GAP82667.1 - 0.056 13.4 0.2 0.067 13.1 0.2 1.1 1 0 0 1 1 1 0 Glycoside hydrolase family 44 RskA PF10099.9 GAP82668.1 - 0.023 15.0 3.3 0.53 10.6 4.3 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA FAM176 PF14851.6 GAP82668.1 - 0.18 11.5 15.5 0.39 10.4 9.2 2.5 2 0 0 2 2 2 0 FAM176 family Presenilin PF01080.17 GAP82668.1 - 0.82 8.4 1.9 1.1 7.9 1.9 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 GAP82668.1 - 0.98 8.1 3.4 0.25 10.1 0.2 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIA PF03153.13 GAP82668.1 - 1.1 9.2 21.5 1.4 8.9 21.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myc_N PF01056.18 GAP82668.1 - 1.1 9.1 5.3 2.2 8.1 5.3 1.6 1 0 0 1 1 1 0 Myc amino-terminal region SAPS PF04499.15 GAP82668.1 - 1.6 7.4 4.4 2 7.1 4.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Trypan_PARP PF05887.11 GAP82668.1 - 2 8.4 10.6 4.1 7.4 10.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2457 PF10446.9 GAP82668.1 - 2.3 7.3 42.8 0.2 10.8 33.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 GAP82668.1 - 5 5.3 27.0 3 6.0 18.0 2.0 2 0 0 2 2 2 0 CDC45-like protein RPA43_OB PF17875.1 GAP82668.1 - 5.8 7.6 7.3 1.6 9.4 2.2 2.1 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Afi1 PF07792.12 GAP82668.1 - 9.4 6.7 15.0 3.3 8.2 9.5 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ank_2 PF12796.7 GAP82669.1 - 6.3e-34 116.4 1.4 6.8e-08 33.0 0.0 10.2 7 3 4 12 12 12 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP82669.1 - 6.2e-29 96.8 21.2 0.00083 19.6 0.1 13.5 16 0 0 16 16 16 6 Ankyrin repeat Ank_4 PF13637.6 GAP82669.1 - 1.3e-26 92.6 5.0 2.6e-06 27.9 0.2 10.2 10 1 1 11 11 11 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP82669.1 - 2.2e-24 85.2 8.5 1.5e-07 31.5 0.0 9.9 9 1 2 11 11 11 4 Ankyrin repeats (many copies) Ank PF00023.30 GAP82669.1 - 2e-21 75.4 11.9 0.007 16.8 0.1 10.8 11 0 0 11 11 11 5 Ankyrin repeat F-box-like PF12937.7 GAP82669.1 - 9.4e-05 22.2 0.0 0.00026 20.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like Phage_min_cap2 PF06152.11 GAP82669.1 - 0.24 10.3 0.0 0.37 9.6 0.0 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 Aconitase PF00330.20 GAP82671.1 - 5.3e-157 523.5 0.0 6.5e-157 523.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAP82671.1 - 8.8e-40 136.1 0.0 1.5e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain TPR_2 PF07719.17 GAP82672.1 - 0.43 10.8 0.1 0.43 10.8 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAP82672.1 - 0.51 11.1 0.1 0.51 11.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAP82672.1 - 0.59 11.1 9.6 0.65 11.0 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Rit1_C PF17184.4 GAP82673.1 - 2e-56 191.4 0.0 2.6e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Rit1 N-terminal domain ketoacyl-synt PF00109.26 GAP82674.1 - 7.1e-78 261.7 0.0 1.3e-77 260.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAP82674.1 - 2.2e-43 149.0 0.0 3.5e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP82674.1 - 3.3e-35 120.7 0.2 7.1e-35 119.6 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 GAP82674.1 - 1.4e-25 90.4 0.2 2.3e-22 79.9 0.0 3.4 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PS-DH PF14765.6 GAP82674.1 - 3e-24 85.8 0.0 5.1e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 GAP82674.1 - 2.2e-18 67.3 0.0 7e-18 65.6 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 GAP82674.1 - 2.3e-15 56.7 1.7 7.5e-09 35.8 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAP82674.1 - 1.4e-08 35.2 0.1 4e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 GAP82674.1 - 1.4e-06 29.1 0.0 0.0003 21.5 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 GAP82674.1 - 3.3e-05 23.4 0.1 6.9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.13 GAP82674.1 - 0.19 11.6 0.0 0.61 9.9 0.0 1.8 1 0 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.28 GAP82675.1 - 4.6e-34 117.7 0.0 1.6e-33 116.0 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAP82675.1 - 1.4e-11 44.1 0.0 5.7e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 GAP82675.1 - 1.6e-06 28.4 0.1 6.3e-06 26.4 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 GAP82675.1 - 0.034 13.6 0.0 0.2 11.1 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HET PF06985.11 GAP82676.1 - 5e-33 114.5 0.1 8.9e-33 113.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RPA_interact_M PF14767.6 GAP82676.1 - 0.15 12.6 0.1 0.3 11.7 0.1 1.4 1 0 0 1 1 1 0 Replication protein A interacting middle PhyH PF05721.13 GAP82678.1 - 0.09 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_3 PF01494.19 GAP82679.1 - 6.9e-44 150.5 0.0 3.8e-43 148.1 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAP82679.1 - 1.6e-06 28.2 0.0 5.5e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Methyltransf_2 PF00891.18 GAP82680.1 - 3.2e-23 82.2 0.0 9.9e-23 80.5 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 GAP82680.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Dimerisation2 PF16864.5 GAP82680.1 - 0.053 13.5 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_25 PF13649.6 GAP82680.1 - 0.055 14.2 0.0 0.14 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain B-block_TFIIIC PF04182.12 GAP82680.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC adh_short PF00106.25 GAP82681.1 - 1.8e-16 60.2 0.2 1.5e-15 57.2 0.3 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP82681.1 - 2e-12 47.2 0.5 7.3e-12 45.3 0.5 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 GAP82681.1 - 0.02 14.0 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain S-AdoMet_synt_C PF02773.16 GAP82682.1 - 4.8e-64 214.5 0.0 7.5e-64 213.9 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 GAP82682.1 - 1.5e-44 150.7 0.1 3.1e-44 149.7 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 GAP82682.1 - 1.4e-42 144.7 0.0 3.1e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 GAP82682.1 - 0.057 12.2 0.3 0.15 10.9 0.1 1.6 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Methyltransf_24 PF13578.6 GAP82683.1 - 2.7e-06 28.4 0.0 4.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 GAP82683.1 - 6.6e-05 22.2 0.0 9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase ATP_bind_1 PF03029.17 GAP82684.1 - 6.8e-70 235.6 0.0 1e-68 231.8 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 GAP82684.1 - 0.0035 17.4 0.0 0.0073 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAP82684.1 - 0.0039 17.4 0.0 0.0071 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 GAP82684.1 - 0.0049 16.7 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 GAP82684.1 - 0.0075 16.3 0.0 0.0088 16.1 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain TRADD_N PF09034.10 GAP82684.1 - 0.0076 16.3 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 TRADD, N-terminal domain AAA_18 PF13238.6 GAP82684.1 - 0.0084 16.7 0.1 0.049 14.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAP82684.1 - 0.0093 16.3 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 GAP82684.1 - 0.023 14.4 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 GAP82684.1 - 0.029 13.6 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_29 PF13555.6 GAP82684.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAP82684.1 - 0.059 13.9 0.0 0.17 12.4 0.0 1.7 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 GAP82684.1 - 0.081 12.8 0.1 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 GAP82684.1 - 0.098 12.7 0.0 0.34 11.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 GAP82684.1 - 0.099 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 GAP82684.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Apq12 PF12716.7 GAP82685.1 - 2.7e-09 36.8 12.0 2.7e-09 36.8 12.0 2.1 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis DUF4131 PF13567.6 GAP82685.1 - 0.5 10.0 4.9 0.64 9.7 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pro-kuma_activ PF09286.11 GAP82686.1 - 1.7e-46 158.0 0.0 2.7e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAP82686.1 - 0.00057 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Subtilase family AAA PF00004.29 GAP82687.1 - 6.9e-42 143.0 0.4 8.4e-14 52.1 0.0 5.4 6 0 0 6 6 4 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 GAP82687.1 - 7.2e-38 130.2 0.0 1.7e-37 129.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAP82687.1 - 1.3e-23 84.1 31.4 1.7e-23 83.8 0.0 6.5 6 1 0 6 6 5 2 AAA domain AAA_lid_6 PF17866.1 GAP82687.1 - 4.3e-18 65.2 6.8 7.9e-08 32.4 0.0 4.6 4 0 0 4 4 3 2 AAA lid domain AAA_30 PF13604.6 GAP82687.1 - 9.8e-16 58.0 13.5 0.00022 21.0 0.0 6.3 6 0 0 6 6 5 4 AAA domain AAA_19 PF13245.6 GAP82687.1 - 2.1e-12 47.6 8.0 2.8e-06 27.7 0.0 6.0 4 2 1 5 5 5 1 AAA domain AAA_5 PF07728.14 GAP82687.1 - 5.1e-11 42.7 0.9 0.86 9.6 0.0 5.3 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP82687.1 - 9.4e-10 38.9 16.4 0.7 10.2 0.1 8.9 6 3 1 8 8 7 4 AAA domain Mg_chelatase PF01078.21 GAP82687.1 - 1.1e-07 31.5 2.3 0.29 10.5 0.0 4.8 5 0 0 5 5 5 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 GAP82687.1 - 1.2e-07 32.4 3.8 1.3 9.6 0.0 5.6 5 0 0 5 5 4 2 AAA domain Viral_helicase1 PF01443.18 GAP82687.1 - 1.3e-06 28.3 1.1 0.59 9.8 0.0 5.3 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 GAP82687.1 - 1.4e-06 28.6 1.7 3.1 8.2 0.0 5.0 5 0 0 5 5 4 1 RNA helicase AAA_24 PF13479.6 GAP82687.1 - 1.5e-06 28.1 5.3 0.51 10.0 0.1 4.6 4 0 0 4 4 4 3 AAA domain RuvB_N PF05496.12 GAP82687.1 - 1.9e-06 27.7 3.2 1.3 8.7 0.0 5.1 5 1 0 5 5 4 3 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAP82687.1 - 4.9e-06 27.0 17.0 2 8.8 0.1 6.4 6 0 0 6 6 4 4 AAA ATPase domain AAA_7 PF12775.7 GAP82687.1 - 0.00017 21.1 0.8 14 5.1 0.0 4.4 4 0 0 4 4 4 0 P-loop containing dynein motor region ResIII PF04851.15 GAP82687.1 - 0.00072 19.6 0.5 1.1 9.3 0.0 4.7 6 0 0 6 6 5 1 Type III restriction enzyme, res subunit Rad17 PF03215.15 GAP82687.1 - 0.031 14.2 0.1 15 5.4 0.0 3.6 4 0 0 4 4 3 0 Rad17 P-loop domain DUF2075 PF09848.9 GAP82687.1 - 0.054 12.7 0.0 0.054 12.7 0.0 6.2 7 1 0 8 8 7 0 Uncharacterized conserved protein (DUF2075) Adeno_IVa2 PF02456.15 GAP82687.1 - 0.091 11.5 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_6 PF12774.7 GAP82687.1 - 0.15 11.0 1.6 8.2 5.3 0.0 3.7 4 0 0 4 4 4 0 Hydrolytic ATP binding site of dynein motor region ATPase PF06745.13 GAP82687.1 - 0.17 11.2 4.2 4.9 6.4 0.0 3.8 4 0 0 4 4 4 0 KaiC AAA_25 PF13481.6 GAP82687.1 - 0.76 9.3 7.3 12 5.4 0.0 4.6 4 0 0 4 4 4 0 AAA domain Vanabin-2 PF11437.8 GAP82687.1 - 2.6 8.2 11.8 7.8 6.7 11.8 1.8 1 0 0 1 1 1 0 Vanadium-binding protein 2 Myb_DNA-bind_6 PF13921.6 GAP82688.1 - 0.02 15.1 0.2 0.037 14.3 0.2 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 GAP82688.1 - 0.038 13.8 0.2 0.096 12.5 0.1 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Myb_DNA-binding PF00249.31 GAP82688.1 - 0.11 12.7 2.3 0.19 12.0 2.3 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain IFT57 PF10498.9 GAP82688.1 - 0.19 10.6 0.6 0.25 10.3 0.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 IBR PF01485.21 GAP82690.1 - 1.9e-15 56.9 13.6 3.8e-08 33.4 10.6 2.2 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Hydrolase_3 PF08282.12 GAP82691.1 - 2.4e-10 40.6 0.0 2.4e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMM PF03332.13 GAP82691.1 - 4.7e-07 29.8 0.0 8.8e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic phosphomannomutase S6PP PF05116.13 GAP82691.1 - 0.0036 16.9 0.0 0.028 14.0 0.0 2.2 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 GAP82691.1 - 0.073 13.3 0.1 2.1 8.6 0.0 2.2 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Zn_ribbon_17 PF17120.5 GAP82692.1 - 0.23 11.1 9.7 0.39 10.4 9.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-B_box PF00643.24 GAP82692.1 - 0.83 9.9 13.5 1.4 9.1 13.5 1.3 1 0 0 1 1 1 0 B-box zinc finger C1_2 PF03107.16 GAP82692.1 - 1.3 9.4 11.2 2.3 8.6 11.2 1.4 1 0 0 1 1 1 0 C1 domain Hairpins PF04877.12 GAP82693.1 - 0.033 13.8 0.0 0.049 13.3 0.0 1.1 1 0 0 1 1 1 0 HrpZ PP2C PF00481.21 GAP82694.1 - 4.1e-38 131.5 0.0 6.8e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Glyoxalase PF00903.25 GAP82695.1 - 4.7e-07 30.0 0.0 1.2e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RskA PF10099.9 GAP82695.1 - 0.035 14.4 8.6 0.048 13.9 8.6 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA PepSY_2 PF13670.6 GAP82695.1 - 0.92 9.5 6.7 1.9 8.6 6.7 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF3446 PF11928.8 GAP82695.1 - 3.2 8.1 13.2 0.17 12.2 6.0 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Nab2 PF11517.8 GAP82696.1 - 0.19 12.0 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Ribonuclease_3 PF00636.26 GAP82698.1 - 2.3e-41 140.7 0.7 2.8e-20 72.9 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAP82698.1 - 3.9e-25 88.5 0.0 8.1e-11 42.2 0.0 3.7 2 2 1 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 GAP82698.1 - 3.3e-22 78.4 0.3 2.3e-21 75.7 0.1 2.4 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 GAP82698.1 - 3e-19 69.4 0.0 7.6e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP82698.1 - 1e-14 54.9 0.2 1e-14 54.9 0.2 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAP82698.1 - 1e-14 54.7 0.0 1.9e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAP82698.1 - 0.031 14.5 0.7 0.095 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAP82698.1 - 0.034 13.4 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 GAP82698.1 - 0.062 12.5 0.1 0.31 10.2 0.1 2.1 1 1 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2192 PF09958.9 GAP82698.1 - 0.091 12.3 0.0 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2192) TAP42 PF04177.12 GAP82699.1 - 9.1e-107 356.9 0.1 1e-106 356.7 0.1 1.0 1 0 0 1 1 1 1 TAP42-like family ELM2 PF01448.24 GAP82699.1 - 0.07 13.9 0.3 0.28 12.0 0.0 2.2 2 0 0 2 2 2 0 ELM2 domain HHH PF00633.23 GAP82700.1 - 0.023 14.6 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif CDC73_C PF05179.14 GAP82701.1 - 4.9e-61 205.0 0.0 7.5e-61 204.4 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal RGS PF00615.19 GAP82702.1 - 1.3e-34 119.0 0.1 4e-34 117.4 0.0 1.9 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 GAP82702.1 - 1.3e-22 79.6 0.0 1.5e-18 66.6 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ORC4_C PF14629.6 GAP82704.1 - 2.6e-66 223.1 0.0 3.9e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 GAP82704.1 - 3.6e-11 43.7 0.0 7.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PHD PF00628.29 GAP82704.1 - 8.6e-11 41.6 6.8 1.5e-10 40.8 6.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAP82704.1 - 4.6e-10 38.9 1.7 8.5e-10 38.0 1.7 1.5 1 0 0 1 1 1 1 PHD-finger AAA PF00004.29 GAP82704.1 - 2.7e-07 31.1 0.0 6.9e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAP82704.1 - 2.5e-06 27.8 0.0 6.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 GAP82704.1 - 7e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 GAP82704.1 - 0.00023 21.5 0.1 0.00044 20.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAP82704.1 - 0.0006 19.8 0.0 0.0023 17.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain FYVE_2 PF02318.16 GAP82704.1 - 0.00091 19.4 0.1 0.0041 17.3 0.2 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger NB-ARC PF00931.22 GAP82704.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 GAP82704.1 - 0.0017 18.4 0.1 0.0066 16.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAP82704.1 - 0.0022 17.8 0.0 0.0057 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 GAP82704.1 - 0.0034 16.7 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Prok-RING_1 PF14446.6 GAP82704.1 - 0.0049 16.8 4.9 0.011 15.6 4.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 AAA_7 PF12775.7 GAP82704.1 - 0.0088 15.6 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region C1_1 PF00130.22 GAP82704.1 - 0.017 15.0 0.2 0.036 13.9 0.2 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ATP-synt_ab PF00006.25 GAP82704.1 - 0.041 13.5 0.1 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 GAP82704.1 - 0.084 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 GAP82704.1 - 0.12 11.2 0.1 0.25 10.2 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Zf_RING PF16744.5 GAP82704.1 - 0.23 11.6 7.3 0.052 13.7 3.6 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RING_2 PF13639.6 GAP82704.1 - 4 7.9 8.5 7.5 7.0 8.5 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 GAP82704.1 - 7.1 6.5 6.1 16 5.4 6.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger Prim_Zn_Ribbon PF08273.12 GAP82704.1 - 9.4 6.6 8.0 2.3 8.6 3.8 2.2 2 1 0 2 2 1 0 Zinc-binding domain of primase-helicase FAD_binding_3 PF01494.19 GAP82705.1 - 4.9e-09 35.9 0.1 5.7e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAP82705.1 - 3.4e-07 30.4 0.5 7.6e-07 29.3 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAP82705.1 - 3e-05 23.3 0.6 3.8e-05 23.0 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP82705.1 - 0.00011 21.9 0.2 0.00015 21.5 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAP82705.1 - 0.0002 21.9 0.1 0.0003 21.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP82705.1 - 0.00027 20.2 0.0 0.00039 19.7 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAP82705.1 - 0.00084 18.7 0.1 0.0012 18.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP82705.1 - 0.00095 18.5 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAP82705.1 - 0.0014 17.6 0.1 0.0017 17.3 0.1 1.1 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 GAP82705.1 - 0.002 17.3 0.1 0.0025 17.0 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAP82705.1 - 0.019 14.2 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GAP82705.1 - 0.025 14.4 0.1 0.034 14.0 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 GAP82705.1 - 0.028 13.8 0.2 0.036 13.4 0.2 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAP82705.1 - 0.034 12.9 0.1 0.042 12.6 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 GAP82705.1 - 0.045 12.8 0.2 0.06 12.4 0.2 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 GAP82705.1 - 0.09 12.4 0.4 0.12 12.0 0.4 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 GAP82705.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF5510 PF17629.2 GAP82705.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5510) TrkA_N PF02254.18 GAP82705.1 - 0.18 12.0 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Git3 PF11710.8 GAP82707.1 - 2.7e-50 171.0 19.6 4.5e-50 170.3 19.6 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 GAP82707.1 - 2e-17 63.0 0.6 1.3e-11 44.4 0.2 3.0 2 0 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 GAP82707.1 - 1e-07 31.6 0.3 1.7e-07 30.8 0.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ABC_cobalt PF09819.9 GAP82707.1 - 0.028 14.6 9.0 0.041 14.0 2.9 2.6 1 1 1 2 2 2 0 ABC-type cobalt transport system, permease component GATase PF00117.28 GAP82708.1 - 5.6e-07 29.5 0.7 0.0019 18.0 0.3 2.3 1 1 1 2 2 2 2 Glutamine amidotransferase class-I F-box-like PF12937.7 GAP82709.1 - 1.2e-07 31.5 1.2 2.2e-07 30.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAP82709.1 - 5.3e-07 29.3 0.2 9.6e-07 28.5 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAP82709.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 F-box 2OG-FeII_Oxy PF03171.20 GAP82710.1 - 0.057 13.9 0.0 0.096 13.2 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 GAP82711.1 - 3.7e-08 32.7 37.4 3.7e-08 32.7 37.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily YjcB PF15940.5 GAP82711.1 - 0.024 14.8 0.1 0.11 12.7 0.1 2.2 1 0 0 1 1 1 0 Family of unknown function HNOBA PF07701.14 GAP82712.1 - 0.045 13.2 0.4 0.067 12.6 0.4 1.2 1 0 0 1 1 1 0 Heme NO binding associated F-box-like PF12937.7 GAP82712.1 - 0.07 13.0 0.2 1.1 9.2 0.1 2.6 2 1 0 2 2 2 0 F-box-like Sporozoite_P67 PF05642.11 GAP82713.1 - 0.38 8.8 9.2 0.39 8.7 9.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen K_oxygenase PF13434.6 GAP82714.1 - 1.2e-14 54.2 0.0 2.6e-08 33.4 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAP82714.1 - 7.9e-10 38.5 0.0 7.3e-05 22.2 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP82714.1 - 8.1e-09 35.1 0.0 2.3e-05 23.8 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP82714.1 - 4.3e-05 23.3 0.0 0.46 10.0 0.0 4.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAP82714.1 - 0.00083 19.4 0.0 0.015 15.3 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAP82714.1 - 0.0027 17.0 0.1 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 GAP82714.1 - 0.0053 16.1 1.1 0.59 9.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Shikimate_DH PF01488.20 GAP82714.1 - 0.011 15.8 0.1 0.82 9.7 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 GAP82714.1 - 0.011 14.4 0.0 0.49 9.0 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 GAP82714.1 - 0.013 14.6 0.3 0.038 13.0 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAP82714.1 - 0.018 15.6 2.1 7.7 7.1 0.1 3.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.15 GAP82714.1 - 0.027 13.8 0.1 0.06 12.6 0.0 1.5 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_binding_8 PF13450.6 GAP82714.1 - 0.041 14.1 1.1 0.91 9.8 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF2196 PF09962.9 GAP82716.1 - 6.5e-22 77.3 4.5 1.1e-21 76.6 4.5 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) TOBE_2 PF08402.10 GAP82716.1 - 0.025 14.7 0.2 0.059 13.5 0.2 1.7 1 0 0 1 1 1 0 TOBE domain Abhydrolase_3 PF07859.13 GAP82717.1 - 1.9e-42 145.5 0.0 2.6e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAP82717.1 - 2.4e-05 23.4 0.0 4.4e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 GAP82717.1 - 0.0051 17.4 0.8 0.0084 16.7 0.8 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAP82717.1 - 0.0083 15.6 0.0 0.07 12.6 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 GAP82717.1 - 0.0099 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Kinesin PF00225.23 GAP82718.1 - 5.9e-50 170.1 0.0 6.7e-41 140.3 0.0 2.7 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 GAP82718.1 - 3.1e-25 88.9 0.0 6.8e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Ribosomal_S21 PF01165.20 GAP82718.1 - 1.5e-14 53.4 7.4 2.3e-14 52.8 4.7 2.8 2 0 0 2 2 2 1 Ribosomal protein S21 Rz1 PF06085.11 GAP82718.1 - 0.17 11.6 1.7 0.59 9.9 0.1 2.6 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor PWI PF01480.17 GAP82719.1 - 3.3e-14 52.9 0.7 7.7e-14 51.8 0.7 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 GAP82719.1 - 0.0047 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAF8_C PF10406.9 GAP82719.1 - 0.28 11.8 0.9 2.9 8.5 0.9 2.8 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term ECH_1 PF00378.20 GAP82720.1 - 6.5e-45 153.4 0.0 7.7e-34 117.1 0.2 2.4 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAP82720.1 - 3.6e-20 72.7 2.8 1.3e-09 38.0 1.8 2.8 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase Glyco_hydro_28 PF00295.17 GAP82721.1 - 5.6e-47 160.4 0.4 7.3e-47 160.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 SDH_alpha PF03313.15 GAP82721.1 - 0.13 11.9 1.1 0.24 11.0 1.1 1.3 1 0 0 1 1 1 0 Serine dehydratase alpha chain SH3_9 PF14604.6 GAP82722.1 - 9.6e-11 41.4 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAP82722.1 - 7.9e-08 31.8 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAP82722.1 - 2e-06 27.4 0.0 3.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Protocadherin PF08374.11 GAP82722.1 - 0.31 11.0 0.0 0.31 11.0 0.0 2.4 2 1 0 2 2 2 0 Protocadherin Gar1 PF04410.14 GAP82724.1 - 8.7e-42 142.5 0.1 8.7e-42 142.5 0.1 1.6 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.17 GAP82725.1 - 2e-79 267.8 17.9 2.4e-79 267.5 17.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_hydro_43 PF04616.14 GAP82726.1 - 7.1e-29 101.0 0.1 9.1e-29 100.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HNF-1A_C PF04813.12 GAP82727.1 - 0.082 13.7 2.1 0.13 13.0 1.5 1.5 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus CBM_1 PF00734.18 GAP82728.1 - 2e-09 37.2 9.2 4.4e-09 36.2 9.2 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain DNase_NucA_NucB PF14040.6 GAP82729.1 - 5.2e-37 126.7 2.0 5.4e-37 126.7 1.0 1.5 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB DUF3953 PF13129.6 GAP82730.1 - 0.13 12.1 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) CoA_binding_2 PF13380.6 GAP82731.1 - 9.1e-29 100.3 0.1 1.1e-28 100.0 0.1 1.1 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.12 GAP82733.1 - 6.5e-17 62.0 0.0 1.1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP82733.1 - 6e-16 58.9 0.0 1.1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP82733.1 - 1.5e-09 38.5 0.0 2.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP82733.1 - 6.7e-08 32.5 0.0 9.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP82733.1 - 9.4e-06 25.5 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 GAP82733.1 - 0.00033 19.8 0.0 0.00055 19.1 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 GAP82733.1 - 0.0026 17.1 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 GAP82733.1 - 0.005 16.8 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP82733.1 - 0.0072 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 GAP82733.1 - 0.015 14.3 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_32 PF13679.6 GAP82733.1 - 0.023 14.7 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 GAP82733.1 - 0.027 14.1 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) EF-hand_9 PF14658.6 GAP82734.1 - 5.7e-12 45.8 0.0 2.4e-05 24.6 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GAP82734.1 - 6e-12 45.9 0.1 1.9e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAP82734.1 - 3.9e-09 35.7 0.5 0.00013 21.7 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 GAP82734.1 - 9.9e-09 34.9 0.1 5.5e-05 22.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 GAP82734.1 - 2.5e-08 32.9 0.1 0.00049 19.5 0.0 3.7 4 1 0 4 4 4 2 EF hand EF-hand_14 PF17959.1 GAP82734.1 - 0.091 13.1 0.0 5.6 7.4 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain Peptidase_M3 PF01432.20 GAP82735.1 - 1.3e-157 525.8 0.0 1.5e-157 525.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 GAP82735.1 - 0.12 12.7 0.1 0.4 11.0 0.0 1.9 2 0 0 2 2 2 0 Effector protein BIR PF00653.21 GAP82736.1 - 5.8e-44 148.6 3.9 2e-22 79.6 1.6 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-ribbon_3 PF13248.6 GAP82736.1 - 8.6 5.9 5.4 29 4.2 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain CobS PF02654.15 GAP82737.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase Lactamase_B_3 PF13483.6 GAP82738.1 - 1.5e-05 25.0 0.0 2.9e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 GAP82738.1 - 6e-05 22.7 0.1 0.00025 20.6 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain nec1 PF10379.9 GAP82740.1 - 0.047 13.2 0.3 0.069 12.6 0.3 1.2 1 0 0 1 1 1 0 Virulence protein nec1 MSA-2c PF12238.8 GAP82741.1 - 0.56 10.2 2.2 1.1 9.2 2.2 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c DSPc PF00782.20 GAP82742.1 - 1.7e-11 44.1 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4679 PF15728.5 GAP82743.1 - 0.19 10.7 7.9 0.26 10.3 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) Spo7 PF03907.13 GAP82744.1 - 2.1e-92 308.6 0.0 3.1e-92 308.0 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_1 PF00561.20 GAP82745.1 - 4.1e-20 72.5 0.0 2.6e-19 69.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP82745.1 - 7e-15 54.9 0.0 5.2e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAP82745.1 - 8e-15 56.0 0.8 3.8e-14 53.8 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 GAP82745.1 - 5.6e-06 26.2 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 GAP82745.1 - 4.1e-05 23.1 0.0 7.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 GAP82745.1 - 0.0047 15.9 0.0 0.01 14.7 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 GAP82745.1 - 0.0085 15.7 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 GAP82745.1 - 0.032 14.0 0.0 0.076 12.7 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 GAP82745.1 - 0.035 13.9 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.11 GAP82745.1 - 0.041 13.8 0.0 0.25 11.3 0.0 2.1 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 GAP82745.1 - 0.053 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 GAP82745.1 - 0.069 13.3 0.1 0.26 11.4 0.1 2.0 1 1 0 1 1 1 0 Thioesterase domain DLH PF01738.18 GAP82745.1 - 0.099 12.2 0.0 2 7.9 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 GAP82745.1 - 0.21 11.3 0.0 28 4.4 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase CMD PF02627.20 GAP82746.1 - 6.5e-07 29.3 6.1 6.5e-07 29.3 6.1 2.1 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF1996 PF09362.10 GAP82747.1 - 7.2e-64 216.0 3.6 9.4e-64 215.6 3.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF3405 PF11885.8 GAP82748.1 - 5.1e-110 368.5 6.3 4.4e-109 365.4 6.3 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) SMC_Nse1 PF07574.13 GAP82749.1 - 1.5e-70 237.1 0.2 1.9e-70 236.7 0.2 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 GAP82749.1 - 2.5e-14 53.3 8.9 4.2e-14 52.6 8.9 1.4 1 0 0 1 1 1 1 RING-like domain FYDLN_acid PF09538.10 GAP82749.1 - 0.0022 18.7 0.3 0.0022 18.7 0.3 2.5 2 1 0 2 2 2 1 Protein of unknown function (FYDLN_acid) zf-RING_2 PF13639.6 GAP82749.1 - 0.029 14.7 7.2 0.037 14.4 6.0 1.8 2 0 0 2 2 2 0 Ring finger domain FYVE PF01363.21 GAP82749.1 - 0.057 13.6 4.2 2.4 8.4 1.6 2.4 2 0 0 2 2 2 0 FYVE zinc finger PaaX PF07848.12 GAP82749.1 - 0.095 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein Vps4_C PF09336.10 GAP82749.1 - 0.11 12.6 0.3 1.5 8.9 0.0 2.5 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain zf-HC5HC2H PF13771.6 GAP82749.1 - 0.54 10.5 5.0 1.5 9.1 5.1 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-ribbon_3 PF13248.6 GAP82749.1 - 0.74 9.3 4.2 0.41 10.1 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4 PF00097.25 GAP82749.1 - 6.5 6.7 6.8 15 5.6 6.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAP82749.1 - 8.1 6.1 8.6 8.2 6.1 6.3 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type OAD_gamma PF04277.13 GAP82750.1 - 0.016 15.7 4.2 1.5 9.5 0.0 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF2555 PF10742.9 GAP82751.1 - 0.014 15.2 0.9 0.69 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) SPRY PF00622.28 GAP82752.1 - 0.0066 16.6 0.0 0.34 11.0 0.0 3.2 2 2 1 3 3 3 1 SPRY domain Glyco_hydro_16 PF00722.21 GAP82754.1 - 2.2e-38 131.5 0.3 3.3e-38 130.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ADH_zinc_N PF00107.26 GAP82755.1 - 0.00022 21.2 0.1 0.00023 21.1 0.1 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PHD PF00628.29 GAP82756.1 - 5e-09 35.9 10.8 8.4e-09 35.2 10.8 1.4 1 0 0 1 1 1 1 PHD-finger IMUP PF15761.5 GAP82756.1 - 0.0065 17.2 8.1 0.0065 17.2 8.1 3.2 3 1 1 4 4 4 1 Immortalisation up-regulated protein C1_1 PF00130.22 GAP82756.1 - 0.0083 16.0 6.0 0.0083 16.0 6.0 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 GAP82756.1 - 0.014 14.9 10.3 0.059 12.9 10.3 2.0 1 1 0 1 1 1 0 PHD-finger zf-PHD-like PF15446.6 GAP82756.1 - 0.032 13.9 5.4 0.075 12.6 5.4 1.6 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.16 GAP82756.1 - 0.19 12.0 5.3 0.32 11.2 5.3 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.6 GAP82756.1 - 0.52 10.3 8.7 0.18 11.8 5.3 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RRPl_C4 PF17026.5 GAP82756.1 - 1.3 9.2 5.9 4.3 7.5 5.9 1.7 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_2 PF03107.16 GAP82756.1 - 4.9 7.5 8.8 1.2 9.6 4.0 2.1 2 0 0 2 2 2 0 C1 domain GDE_C PF06202.14 GAP82757.1 - 4.7e-06 25.8 0.1 8e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase F5_F8_type_C PF00754.25 GAP82757.1 - 5.4e-06 26.5 4.0 2.2e-05 24.6 3.9 2.2 1 1 0 1 1 1 1 F5/8 type C domain Trehalase PF01204.18 GAP82757.1 - 0.0038 16.1 0.3 0.0065 15.3 0.3 1.3 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 GAP82757.1 - 0.015 14.1 0.5 0.22 10.3 0.5 2.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain HET PF06985.11 GAP82758.1 - 1.5e-20 74.0 0.0 2e-19 70.4 0.0 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 2OG-FeII_Oxy_3 PF13640.6 GAP82758.1 - 1.2e-07 32.5 0.0 3e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CoA_transf_3 PF02515.17 GAP82759.1 - 2e-126 422.0 0.0 2.4e-126 421.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DUF3602 PF12223.8 GAP82760.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) TMEM154 PF15102.6 GAP82761.1 - 0.093 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.20 GAP82761.1 - 0.26 11.2 0.3 0.51 10.3 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain FeoB_associated PF12669.7 GAP82761.1 - 0.39 11.2 0.9 0.57 10.6 0.9 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Endomucin PF07010.12 GAP82761.1 - 0.57 10.1 1.0 0.87 9.5 1.0 1.2 1 0 0 1 1 1 0 Endomucin TFIIB PF00382.19 GAP82762.1 - 2.9e-32 110.5 1.7 3.6e-20 71.8 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 GAP82762.1 - 1.2e-14 53.6 0.8 5.2e-14 51.5 0.7 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_C PF02984.19 GAP82762.1 - 0.0038 17.3 0.2 0.82 9.8 0.2 2.9 2 1 0 2 2 2 1 Cyclin, C-terminal domain RB_B PF01857.20 GAP82762.1 - 0.0047 17.0 0.2 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain HTH_5 PF01022.20 GAP82762.1 - 0.02 14.7 0.0 5.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Sigma70_r4_2 PF08281.12 GAP82762.1 - 0.029 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 zf-ribbon_3 PF13248.6 GAP82762.1 - 0.039 13.4 1.0 0.098 12.1 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HTH_Tnp_ISL3 PF13542.6 GAP82762.1 - 0.067 12.6 0.0 0.21 11.0 0.0 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Rrf2 PF02082.20 GAP82762.1 - 0.15 12.4 0.0 23 5.5 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator LPMO_10 PF03067.15 GAP82764.1 - 2e-07 31.8 0.1 2.9e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CRC_subunit PF08624.10 GAP82766.1 - 3.9e-52 176.3 0.0 5.9e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Phage-tail_3 PF13550.6 GAP82766.1 - 0.0089 15.9 0.3 0.02 14.8 0.3 1.5 1 0 0 1 1 1 1 Putative phage tail protein Cyclin PF08613.11 GAP82767.1 - 3.8e-07 30.6 0.0 6.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAP82767.1 - 4.9e-06 26.3 0.6 1.3e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Nefa_Nip30_N PF10187.9 GAP82768.1 - 7.9e-29 100.1 9.1 7.9e-29 100.1 9.1 1.6 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 adh_short_C2 PF13561.6 GAP82769.1 - 6.1e-06 26.0 0.0 7e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP82769.1 - 1.6e-05 24.5 0.0 1.8e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Tim54 PF11711.8 GAP82770.1 - 7.9e-140 465.9 0.1 9.1e-140 465.7 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DSBA PF01323.20 GAP82771.1 - 7.3e-12 45.5 0.0 4.3e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Pkinase PF00069.25 GAP82772.1 - 1.6e-57 194.9 0.0 2e-56 191.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP82772.1 - 1.1e-26 93.7 0.2 2e-20 73.2 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAP82772.1 - 5.4e-05 22.3 0.0 7.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAP82772.1 - 0.00017 21.6 4.2 0.031 14.2 0.2 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 GAP82772.1 - 0.00077 18.9 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAP82772.1 - 0.0011 18.3 0.8 0.0026 17.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 GAP82772.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SF3A2 PF16835.5 GAP82773.1 - 2.3e-36 124.0 0.0 3.4e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 GAP82773.1 - 1.5e-06 28.3 1.5 2.9e-06 27.5 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 GAP82773.1 - 0.065 12.8 1.5 0.11 12.0 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like zf-C2H2_jaz PF12171.8 GAP82773.1 - 2.7 8.4 5.2 3.9 7.9 3.8 2.0 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SKG6 PF08693.10 GAP82774.1 - 2.4e-08 33.3 4.3 4.2e-08 32.5 4.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 GAP82774.1 - 0.0042 16.9 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor GT87 PF09594.10 GAP82774.1 - 0.025 14.3 0.2 0.026 14.2 0.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 87 GFA PF04828.14 GAP82775.1 - 1.6e-06 28.4 1.1 2.9e-06 27.5 1.1 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ACC PF17848.1 GAP82775.1 - 0.041 14.0 0.0 6.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain SLATT_fungal PF18142.1 GAP82776.1 - 2.6e-27 95.2 0.6 3.4e-27 94.8 0.6 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain NHL PF01436.21 GAP82777.1 - 0.043 13.9 0.1 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 NHL repeat Nitroreductase PF00881.24 GAP82778.1 - 4.8e-22 78.8 0.2 1.3e-20 74.1 0.2 2.3 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 GAP82778.1 - 0.00067 19.3 0.0 0.068 12.7 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase Peptidase_C12 PF01088.21 GAP82779.1 - 5.5e-26 91.6 0.0 6e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 AAA_16 PF13191.6 GAP82780.1 - 4.3e-07 30.5 0.3 1.8e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP82780.1 - 0.0034 17.7 0.2 0.015 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 GAP82780.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 GAP82780.1 - 0.022 14.7 0.1 0.072 13.0 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 GAP82780.1 - 0.033 13.8 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAP82780.1 - 0.073 13.5 0.2 0.45 11.0 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 GAP82780.1 - 0.087 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 GAP82780.1 - 0.1 11.9 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 GAP82780.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region p450 PF00067.22 GAP82781.1 - 2.8e-46 158.2 0.0 3.5e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.13 GAP82782.1 - 1.9e-24 86.5 0.0 1.3e-23 83.8 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) NmrA PF05368.13 GAP82783.1 - 7.8e-42 143.4 0.0 1.2e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP82783.1 - 2e-10 40.8 0.0 3.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP82783.1 - 5.9e-05 22.6 0.0 8.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAP82783.1 - 0.00055 20.2 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 GAP82783.1 - 0.0016 17.5 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 GAP82783.1 - 0.0038 17.5 0.0 0.0064 16.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 GAP82783.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 GAP82783.1 - 0.017 15.5 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PHBC_N PF12551.8 GAP82784.1 - 0.24 11.2 2.5 15 5.5 0.2 3.0 2 1 1 3 3 3 0 Poly-beta-hydroxybutyrate polymerase N terminal DUF3425 PF11905.8 GAP82785.1 - 8.3e-12 45.2 1.3 4e-11 43.0 1.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAP82785.1 - 0.3 11.2 7.8 0.54 10.4 7.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF1295 PF06966.12 GAP82788.1 - 5.8e-12 45.6 0.7 4.9e-11 42.6 0.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 GAP82788.1 - 7.6e-10 38.1 0.2 5.3e-09 35.3 0.2 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 GAP82788.1 - 0.0025 18.2 0.0 0.0038 17.6 0.0 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Kelch_5 PF13854.6 GAP82789.1 - 1e-06 28.6 0.1 0.0036 17.2 0.1 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 GAP82789.1 - 0.011 16.0 0.7 0.18 12.2 0.0 2.5 2 1 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 GAP82789.1 - 0.03 14.6 4.9 0.07 13.4 0.1 2.9 2 1 0 2 2 2 0 Galactose oxidase, central domain SNF5 PF04855.12 GAP82790.1 - 2.4e-91 305.8 0.0 3.3e-91 305.3 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 GAP82790.1 - 1.2e-05 24.8 2.3 2.8e-05 23.6 2.3 1.7 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 GAP82790.1 - 0.39 10.5 7.2 0.26 11.0 1.5 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain GST_N_3 PF13417.6 GAP82791.1 - 3.2e-06 27.5 0.0 4.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAP82791.1 - 0.00058 20.1 0.0 0.00092 19.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAP82791.1 - 0.0086 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Abhydrolase_1 PF00561.20 GAP82793.1 - 3.1e-09 36.8 0.0 3.5e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP82793.1 - 5.3e-08 33.7 6.4 7.7e-07 29.9 6.4 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP82793.1 - 4.6e-06 26.1 0.0 0.00023 20.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Redoxin PF08534.10 GAP82794.1 - 2.3e-08 33.9 0.0 2.4e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin FA_hydroxylase PF04116.13 GAP82795.1 - 6.2e-10 39.5 0.2 6.2e-10 39.5 0.2 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Acyl-CoA_dh_M PF02770.19 GAP82796.1 - 0.00071 19.7 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Peptidase_M28 PF04389.17 GAP82797.1 - 5e-31 107.9 0.0 8.4e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAP82797.1 - 1.1e-12 47.7 1.7 2.9e-12 46.4 1.7 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 GAP82797.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 ThiF PF00899.21 GAP82798.1 - 1.4e-10 41.0 0.0 1.8e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family TPR_12 PF13424.6 GAP82799.1 - 7.1e-37 125.6 17.3 2.6e-17 62.9 0.1 5.5 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAP82799.1 - 3.2e-36 122.2 27.2 3.6e-12 45.7 0.0 9.0 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 GAP82799.1 - 2.6e-11 42.8 5.8 0.0052 16.6 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP82799.1 - 3.4e-11 42.3 5.2 0.0073 16.3 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP82799.1 - 2.3e-10 39.9 2.9 0.017 15.3 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAP82799.1 - 2.3e-08 34.4 19.1 0.037 14.5 0.1 6.9 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAP82799.1 - 3.1e-08 33.1 12.3 0.065 13.4 0.0 6.6 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 GAP82799.1 - 1.7e-07 30.9 15.9 0.0016 17.9 7.6 2.4 1 1 1 2 2 2 2 MalT-like TPR region AAA_22 PF13401.6 GAP82799.1 - 1.8e-07 31.5 0.0 8.1e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain TPR_16 PF13432.6 GAP82799.1 - 3.6e-06 27.5 17.3 0.007 17.0 0.0 6.8 8 1 0 8 8 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 GAP82799.1 - 1.9e-05 24.0 0.0 0.00054 19.2 0.0 2.4 1 1 0 1 1 1 1 NB-ARC domain ANAPC3 PF12895.7 GAP82799.1 - 0.00015 21.9 5.6 1.6 9.0 0.1 4.7 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 GAP82799.1 - 0.00017 22.1 21.3 2.4 9.2 0.0 8.1 7 1 2 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAP82799.1 - 0.00021 21.4 4.1 4 8.0 0.0 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP82799.1 - 0.00034 21.0 5.1 21 6.0 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_16 PF13191.6 GAP82799.1 - 0.00079 19.9 0.0 0.0035 17.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain PPR PF01535.20 GAP82799.1 - 0.0069 16.6 0.3 20 5.7 0.0 4.9 6 0 0 6 6 6 0 PPR repeat TniB PF05621.11 GAP82799.1 - 0.0083 15.6 0.0 0.032 13.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein TPR_4 PF07721.14 GAP82799.1 - 0.042 14.5 22.2 0.32 11.7 0.0 7.3 8 0 0 8 8 5 0 Tetratricopeptide repeat Methyltransf_2 PF00891.18 GAP82801.1 - 1.9e-25 89.4 0.0 3.1e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAP82801.1 - 0.018 15.7 0.0 0.04 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GST_C PF00043.25 GAP82801.1 - 0.056 13.7 0.0 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SNF2_N PF00176.23 GAP82803.1 - 1.2e-41 142.6 0.0 5.1e-41 140.5 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP82803.1 - 4.4e-14 52.8 0.0 1.4e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 GAP82803.1 - 5.2e-06 26.2 7.0 1.2e-05 25.1 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP82803.1 - 1.4e-05 25.0 6.5 3.2e-05 23.8 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAP82803.1 - 1.5e-05 24.7 8.9 1.5e-05 24.7 8.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 GAP82803.1 - 7.3e-05 22.8 0.0 0.00022 21.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 GAP82803.1 - 0.00014 21.8 6.1 0.00038 20.4 6.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAP82803.1 - 0.00027 20.7 6.8 0.00071 19.4 6.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 GAP82803.1 - 0.00033 20.0 0.1 0.00064 19.0 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Prok-RING_4 PF14447.6 GAP82803.1 - 0.00049 19.9 7.5 0.0012 18.7 7.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 GAP82803.1 - 0.0015 18.8 5.8 0.0015 18.8 5.8 2.5 3 0 0 3 3 2 1 Ring finger domain AAA_34 PF13872.6 GAP82803.1 - 0.025 13.5 0.4 0.075 11.9 0.1 2.0 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 zf-RING_10 PF16685.5 GAP82803.1 - 0.33 11.1 7.1 1 9.5 7.1 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 GAP82803.1 - 0.66 10.2 7.3 1.9 8.7 7.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 GAP82803.1 - 7.4 6.9 9.2 1.3 9.3 3.2 2.8 3 0 0 3 3 2 0 RING-H2 zinc finger domain Peptidase_M20 PF01546.28 GAP82804.1 - 1.9e-20 73.5 0.6 2.8e-19 69.7 0.6 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAP82804.1 - 1.4e-18 66.8 0.0 2.3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAP82804.1 - 7.7e-06 25.7 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 HD_3 PF13023.6 GAP82805.1 - 2.8e-50 170.5 0.0 3.6e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 GAP82805.1 - 6.6e-10 39.0 0.0 9e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Glyco_hydro_61 PF03443.14 GAP82808.1 - 4e-18 66.1 0.2 4.4e-18 66.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Astacin PF01400.24 GAP82810.1 - 3.6e-06 26.7 0.3 9.8e-06 25.3 0.3 1.8 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 GAP82810.1 - 0.00084 19.5 0.1 0.0015 18.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 GAP82810.1 - 0.022 14.6 3.9 0.055 13.3 0.8 2.5 2 1 0 3 3 3 0 Matrixin PCP_red PF08369.10 GAP82810.1 - 0.096 12.9 1.0 0.18 12.1 1.0 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Reprolysin_2 PF13574.6 GAP82810.1 - 0.12 12.3 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAP82810.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 GAP82810.1 - 0.13 12.8 0.1 0.23 12.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M48 PF01435.18 GAP82810.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 DUF3808 PF10300.9 GAP82811.1 - 2.3e-126 422.4 0.0 3.3e-126 421.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 GAP82811.1 - 0.00093 19.1 2.3 0.24 11.6 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAP82811.1 - 0.0024 17.5 1.3 0.095 12.4 0.0 2.9 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 GAP82811.1 - 0.061 13.6 0.2 0.3 11.4 0.2 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAP82811.1 - 0.11 13.1 2.8 35 5.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAP82811.1 - 0.21 11.5 1.3 28 4.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAP82811.1 - 0.29 11.6 2.2 1.6 9.3 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAP82811.1 - 0.53 11.0 2.8 0.98 10.1 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAP82811.1 - 2.8 8.8 8.9 14 6.7 0.7 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAP82811.1 - 7.8 7.6 9.2 2.3 9.2 0.1 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DSS1_SEM1 PF05160.13 GAP82813.1 - 3.2e-22 78.3 10.7 5e-22 77.7 10.7 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.19 GAP82814.1 - 9.4e-152 505.3 0.8 1.1e-151 505.2 0.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 GAP82814.1 - 0.017 15.1 2.6 0.26 11.3 0.0 3.5 4 1 1 5 5 5 0 PA domain PP_kinase_C_1 PF17941.1 GAP82814.1 - 0.042 13.4 0.0 9.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Polyphosphate kinase C-terminal domain 1 Mpv17_PMP22 PF04117.12 GAP82815.1 - 2.9e-21 75.5 0.1 8.7e-21 73.9 0.1 1.9 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2759 PF10958.8 GAP82815.1 - 0.057 13.2 0.2 0.057 13.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) LysM PF01476.20 GAP82818.1 - 0.0025 17.8 0.0 0.0067 16.5 0.0 1.8 1 1 0 1 1 1 1 LysM domain SNF2_N PF00176.23 GAP82819.1 - 3.3e-64 216.8 0.1 4.3e-64 216.5 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP82819.1 - 6.7e-16 58.6 0.2 2.3e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HIRAN PF08797.11 GAP82819.1 - 1.5e-15 56.8 0.0 4.4e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.6 GAP82819.1 - 1.3e-10 41.4 6.5 2.8e-10 40.3 6.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAP82819.1 - 2.9e-09 36.6 7.6 5.8e-09 35.6 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAP82819.1 - 2.4e-08 34.2 3.8 4.8e-08 33.2 3.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 GAP82819.1 - 3.3e-07 30.0 5.9 9.2e-07 28.6 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP82819.1 - 5.2e-07 29.5 6.5 1e-06 28.6 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 GAP82819.1 - 2.1e-06 27.7 0.7 4.6e-06 26.6 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAP82819.1 - 4e-06 26.7 5.6 9e-06 25.6 5.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAP82819.1 - 5.9e-06 26.0 7.7 1.2e-05 25.1 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 GAP82819.1 - 7.5e-05 22.5 3.4 0.00017 21.4 3.4 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 GAP82819.1 - 0.00079 19.2 6.4 0.0075 16.1 6.8 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 GAP82819.1 - 0.0018 17.9 2.4 0.0045 16.7 2.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 GAP82819.1 - 0.014 15.6 5.5 0.026 14.7 5.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAP82819.1 - 0.061 13.2 0.8 1.2 9.1 1.2 2.5 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-TFIIIC PF12660.7 GAP82819.1 - 0.088 12.8 0.4 0.27 11.2 0.4 1.8 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-RING_4 PF14570.6 GAP82819.1 - 0.15 11.9 6.6 0.33 10.8 6.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 GAP82819.1 - 0.19 11.4 4.1 3.2 7.5 0.1 2.5 1 1 1 2 2 2 0 P-11 zinc finger zinc-ribbons_6 PF07191.12 GAP82819.1 - 2.8 8.0 4.6 5.5 7.0 4.6 1.4 1 0 0 1 1 1 0 zinc-ribbons CDO_I PF05995.12 GAP82820.1 - 1.1e-42 145.2 0.1 1.5e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 GAP82820.1 - 0.00011 21.7 0.3 0.00015 21.3 0.3 1.4 1 1 0 1 1 1 1 PCO_ADO DUF1774 PF08611.10 GAP82821.1 - 2.5e-36 123.9 4.0 2.5e-36 123.9 4.0 2.8 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) TRIQK PF15168.6 GAP82821.1 - 3.2 7.7 4.4 4.1 7.4 0.0 2.8 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Acyl-CoA_dh_M PF02770.19 GAP82822.1 - 4.3e-07 30.0 0.0 2e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACPS PF01648.20 GAP82823.1 - 2.1e-07 31.1 0.0 9.8e-07 28.9 0.0 2.1 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 GAP82823.1 - 0.0021 18.1 6.2 0.22 11.7 0.3 2.8 3 0 0 3 3 3 2 4'-phosphopantetheinyl transferase N-terminal domain Chorion_2 PF03964.15 GAP82823.1 - 0.054 14.3 2.1 0.15 12.9 2.1 1.7 1 0 0 1 1 1 0 Chorion family 2 CtnDOT_TraJ PF07863.11 GAP82823.1 - 0.48 11.1 2.5 1.1 9.9 2.5 1.6 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon M20_dimer PF07687.14 GAP82824.1 - 2.1e-18 66.2 0.0 3.9e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 GAP82824.1 - 9.2e-17 61.4 0.5 6e-16 58.8 0.5 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 GAP82824.1 - 5.8e-05 22.9 0.6 9.6e-05 22.2 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M28 Ank_2 PF12796.7 GAP82825.1 - 9.4e-34 115.9 6.2 7.1e-13 49.0 0.1 8.7 4 2 3 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP82825.1 - 2e-26 92.0 16.8 5.3e-08 33.2 0.1 11.7 10 2 2 12 12 12 6 Ankyrin repeats (many copies) Ank PF00023.30 GAP82825.1 - 3e-19 68.5 5.4 0.012 16.0 0.0 9.7 8 1 1 9 9 9 5 Ankyrin repeat Thioredoxin PF00085.20 GAP82825.1 - 2.5e-18 66.0 0.0 5.8e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Ank_5 PF13857.6 GAP82825.1 - 3.9e-16 58.9 5.1 0.00017 21.8 0.1 9.8 7 3 2 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP82825.1 - 4.4e-14 51.2 8.0 0.029 14.9 0.0 11.2 12 0 0 12 12 10 2 Ankyrin repeat NACHT PF05729.12 GAP82825.1 - 9e-10 38.7 0.0 2.6e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 GAP82825.1 - 3.5e-05 23.3 2.1 0.00018 21.0 2.0 2.2 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins OST3_OST6 PF04756.13 GAP82825.1 - 0.0017 17.8 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AAA_22 PF13401.6 GAP82825.1 - 0.0035 17.6 0.0 0.017 15.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AhpC-TSA PF00578.21 GAP82825.1 - 0.012 15.5 0.1 0.17 11.8 0.0 2.7 3 0 0 3 3 3 0 AhpC/TSA family Thioredoxin_8 PF13905.6 GAP82825.1 - 0.013 15.8 0.0 0.14 12.5 0.0 2.9 2 1 0 2 2 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 GAP82825.1 - 0.099 13.1 0.0 0.39 11.2 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAP82825.1 - 0.14 12.3 0.1 0.44 10.8 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin-like SesA PF17107.5 GAP82825.1 - 0.5 10.6 5.4 0.25 11.5 0.1 3.1 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_2 PF12796.7 GAP82826.1 - 4.1e-07 30.5 0.1 0.0021 18.6 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP82826.1 - 0.0013 19.1 0.0 4.2 8.3 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 GAP82826.1 - 0.0028 17.9 0.0 3.7 8.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) cobW PF02492.19 GAP82827.1 - 1.3e-46 158.4 7.8 5.3e-35 120.6 0.9 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 GAP82827.1 - 6.1e-21 74.1 0.1 4.1e-15 55.5 0.1 3.1 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain NOA36 PF06524.12 GAP82827.1 - 0.0011 18.3 8.1 0.0019 17.6 8.1 1.4 1 0 0 1 1 1 1 NOA36 protein GTP_EFTU PF00009.27 GAP82827.1 - 0.0015 18.1 0.2 0.35 10.4 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAP82827.1 - 0.0033 17.3 0.2 1.7 8.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase CDC45 PF02724.14 GAP82827.1 - 0.0038 15.6 2.4 0.0055 15.1 2.4 1.2 1 0 0 1 1 1 1 CDC45-like protein MobB PF03205.14 GAP82827.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B BUD22 PF09073.10 GAP82827.1 - 0.021 14.2 3.1 0.035 13.5 3.1 1.3 1 0 0 1 1 1 0 BUD22 MeaB PF03308.16 GAP82827.1 - 0.022 13.8 0.5 0.71 8.8 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF615 PF04751.14 GAP82827.1 - 0.023 14.7 0.1 0.044 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF615) AAA_18 PF13238.6 GAP82827.1 - 0.044 14.3 1.9 0.097 13.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAP82827.1 - 0.048 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GAP82827.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA ATPase domain GP67 PF17634.2 GAP82827.1 - 0.18 12.3 23.5 0.046 14.1 19.1 2.4 2 0 0 2 2 2 0 Gene product 67 FAM176 PF14851.6 GAP82827.1 - 0.2 11.3 4.6 0.44 10.2 4.6 1.5 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 GAP82827.1 - 0.5 8.5 9.9 0.78 7.9 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 GAP82827.1 - 0.61 9.8 13.2 1.2 8.8 13.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 GAP82827.1 - 1.2 9.1 4.3 2.8 8.0 4.3 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 GAP82827.1 - 1.8 7.7 23.2 2.8 7.0 23.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pes-10 PF07149.11 GAP82827.1 - 7.6 5.5 10.1 16 4.4 10.1 1.4 1 0 0 1 1 1 0 Pes-10 NARP1 PF12569.8 GAP82829.1 - 3.5e-192 639.9 15.9 1.8e-190 634.3 8.2 2.3 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 GAP82829.1 - 2.5e-19 69.6 28.0 6.5e-06 26.6 2.0 7.2 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 GAP82829.1 - 1.2e-15 56.9 24.9 0.0013 19.3 0.0 9.9 7 2 3 10 10 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAP82829.1 - 4.7e-14 52.7 28.6 4.5e-05 24.0 3.3 8.2 8 1 1 9 9 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAP82829.1 - 2.6e-13 49.4 6.8 9.2e-06 25.3 0.4 4.7 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.17 GAP82829.1 - 9.8e-12 44.0 45.5 5.4e-05 23.0 0.1 10.8 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAP82829.1 - 1e-11 44.8 11.2 0.0007 19.7 0.2 7.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP82829.1 - 2e-11 43.1 11.6 0.0012 18.9 0.1 7.6 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP82829.1 - 6.6e-10 39.1 20.7 6e-05 23.2 1.9 5.3 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 GAP82829.1 - 1e-08 34.6 32.4 5.9e-06 25.9 0.2 8.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAP82829.1 - 1.5e-07 31.6 25.2 0.23 11.8 0.1 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 GAP82829.1 - 5.3e-06 25.9 20.6 0.006 15.8 3.3 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAP82829.1 - 0.00014 22.0 16.9 2.8 8.5 0.1 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAP82829.1 - 0.0017 18.2 6.9 16 5.5 0.0 6.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAP82829.1 - 0.0048 17.4 8.0 0.26 12.0 1.1 4.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP82829.1 - 0.037 14.7 27.6 0.8 10.5 0.2 8.7 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAP82829.1 - 0.054 13.5 16.6 16 5.8 0.0 7.1 7 1 1 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAP82829.1 - 2.2 8.4 18.2 1.7 8.8 0.2 5.5 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Cid2 PF09774.9 GAP82830.1 - 1.5e-51 175.0 0.1 1.9e-51 174.7 0.1 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DUF2852 PF11014.8 GAP82830.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) CCD PF07860.11 GAP82830.1 - 0.16 12.0 0.2 0.34 11.0 0.1 1.6 2 0 0 2 2 2 0 WisP family C-Terminal Region RecX PF02631.16 GAP82831.1 - 0.022 15.2 0.0 0.025 15.1 0.0 1.1 1 0 0 1 1 1 0 RecX family AAA PF00004.29 GAP82832.1 - 9.2e-40 136.1 0.0 2e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAP82832.1 - 4.5e-19 68.2 0.1 1.1e-18 66.9 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAP82832.1 - 6e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAP82832.1 - 0.00012 22.1 0.8 0.00072 19.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAP82832.1 - 0.00012 22.5 1.7 0.02 15.3 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 GAP82832.1 - 0.00035 20.4 0.0 0.00092 19.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAP82832.1 - 0.0016 18.6 0.8 0.011 15.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 GAP82832.1 - 0.0057 16.1 0.2 0.081 12.4 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 GAP82832.1 - 0.0075 16.5 4.6 0.083 13.2 0.0 3.2 3 1 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 GAP82832.1 - 0.0084 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 GAP82832.1 - 0.012 14.8 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 GAP82832.1 - 0.014 15.5 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAP82832.1 - 0.076 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 GAP82832.1 - 0.1 12.3 0.1 0.4 10.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAP82832.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 GAP82832.1 - 0.25 11.1 5.2 0.61 9.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain CLZ PF16526.5 GAP82832.1 - 0.54 10.7 4.5 2.4 8.6 4.5 2.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Hydrophobin_2 PF06766.11 GAP82833.1 - 3.9e-27 94.0 8.9 4.9e-27 93.7 8.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Tryp_inh PF17983.1 GAP82833.1 - 0.94 9.6 9.4 1 9.5 1.6 2.4 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 p450 PF00067.22 GAP82834.1 - 6.2e-44 150.5 0.0 9.8e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.22 GAP82836.1 - 3.1e-157 523.8 0.0 3.5e-157 523.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UCH PF00443.29 GAP82837.1 - 3.1e-37 128.5 0.1 2.2e-32 112.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAP82837.1 - 6.9e-07 29.2 3.4 3.7e-05 23.5 3.4 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SSFA2_C PF14723.6 GAP82837.1 - 0.22 11.4 4.5 0.56 10.1 4.5 1.7 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus HAD PF12710.7 GAP82838.1 - 1.6e-23 84.1 0.0 2e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 GAP82838.1 - 0.025 14.0 0.1 0.42 10.0 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase UMPH-1 PF05822.12 GAP82838.1 - 0.13 11.7 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) MFS_1 PF07690.16 GAP82839.1 - 3e-23 82.3 54.7 2.6e-13 49.6 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FMN_dh PF01070.18 GAP82840.1 - 4.8e-49 167.2 1.2 5.3e-49 167.1 1.2 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 GAP82840.1 - 1.7e-08 34.0 0.1 2.1e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAP82840.1 - 7.2e-06 25.2 0.1 8.5e-06 25.0 0.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 GAP82840.1 - 0.00097 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 GAP82840.1 - 0.021 14.2 0.5 0.022 14.1 0.5 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.19 GAP82840.1 - 0.07 12.5 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DHO_dh PF01180.21 GAP82840.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase PI-PLC-X PF00388.19 GAP82841.1 - 2.5e-48 163.4 0.0 4e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAP82841.1 - 6.8e-38 129.6 0.0 1.2e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain adh_short PF00106.25 GAP82841.1 - 2.6e-37 128.2 0.0 4.4e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP82841.1 - 1e-34 120.1 0.1 1.6e-34 119.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP82841.1 - 5.3e-13 49.3 0.2 9.8e-13 48.4 0.2 1.3 1 0 0 1 1 1 1 KR domain C2 PF00168.30 GAP82841.1 - 0.00037 20.7 0.0 0.00074 19.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain tRNA-synt_2 PF00152.20 GAP82842.1 - 5e-69 232.8 0.0 6.2e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAP82842.1 - 0.08 12.9 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain THF_DHG_CYH PF00763.23 GAP82842.1 - 0.086 13.1 0.5 0.2 11.9 0.5 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF3176 PF11374.8 GAP82843.1 - 2.5e-29 101.6 2.9 6.6e-29 100.3 2.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) FtsX PF02687.21 GAP82843.1 - 0.37 11.3 3.2 0.83 10.2 0.0 2.9 3 0 0 3 3 3 0 FtsX-like permease family DUF726 PF05277.12 GAP82844.1 - 7.1e-19 67.9 0.0 7.6e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) BCS1_N PF08740.11 GAP82845.1 - 1.4e-41 142.6 0.3 1.9e-41 142.1 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 GAP82845.1 - 4.1e-18 66.1 0.0 6.2e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP82845.1 - 0.00017 22.0 0.0 0.0005 20.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 GAP82845.1 - 0.0011 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region PPV_E1_C PF00519.17 GAP82845.1 - 0.002 17.0 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Papillomavirus helicase DUF815 PF05673.13 GAP82845.1 - 0.0023 17.1 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GAP82845.1 - 0.0029 17.4 0.0 0.0075 16.0 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 GAP82845.1 - 0.0029 17.2 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAP82845.1 - 0.0052 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 GAP82845.1 - 0.0082 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 GAP82845.1 - 0.009 16.5 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 GAP82845.1 - 0.02 14.6 0.0 0.079 12.7 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 GAP82845.1 - 0.027 15.0 0.0 0.048 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAP82845.1 - 0.03 14.7 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 GAP82845.1 - 0.03 14.4 0.0 0.08 13.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 GAP82845.1 - 0.037 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAP82845.1 - 0.05 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 GAP82845.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 GAP82845.1 - 0.083 13.3 0.1 0.35 11.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAP82845.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 GAP82845.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 GAP82845.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 GAP82845.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 GAP82845.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 NTPase GMC_oxred_N PF00732.19 GAP82846.1 - 8.3e-57 192.8 0.0 1.1e-56 192.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP82846.1 - 2.5e-30 105.9 0.0 5.4e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAP82846.1 - 7.4e-07 28.6 2.7 0.00087 18.5 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAP82846.1 - 5.8e-06 26.1 2.5 0.00071 19.3 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAP82846.1 - 3.6e-05 23.0 0.7 5.7e-05 22.3 0.7 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAP82846.1 - 4.2e-05 22.9 0.1 7.8e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 GAP82846.1 - 4.8e-05 23.5 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAP82846.1 - 8.5e-05 21.9 0.5 0.18 11.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP82846.1 - 0.00036 19.8 0.1 0.0023 17.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP82846.1 - 0.017 13.8 0.1 0.029 13.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 GAP82846.1 - 0.055 12.3 0.2 0.08 11.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 GAP82846.1 - 0.15 11.3 0.3 0.24 10.6 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain UbiA PF01040.18 GAP82847.1 - 2.7e-05 23.6 1.0 3.4e-05 23.3 0.6 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family HILPDA PF15220.6 GAP82848.1 - 0.027 14.6 0.9 0.15 12.2 0.2 1.9 1 1 1 2 2 2 0 Hypoxia-inducible lipid droplet-associated HET PF06985.11 GAP82849.1 - 3.7e-30 105.2 0.1 9.7e-29 100.6 0.1 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 GAP82850.1 - 2.9e-17 62.8 0.0 4.4e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP82850.1 - 4.8e-09 36.1 0.1 6.5e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAP82850.1 - 1.5e-05 24.5 0.0 4.5e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) MFS_1 PF07690.16 GAP82852.1 - 4.6e-32 111.3 32.2 9.5e-23 80.7 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP82852.1 - 6.7e-12 45.0 1.2 6.7e-12 45.0 1.2 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 GAP82852.1 - 0.028 12.8 10.7 0.26 9.6 1.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Pro_dh PF01619.18 GAP82853.1 - 4.8e-10 39.4 0.8 7.6e-10 38.8 0.8 1.3 1 1 0 1 1 1 1 Proline dehydrogenase Lipin_mid PF16876.5 GAP82853.1 - 0.016 15.4 0.1 0.019 15.1 0.1 1.2 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain NUC153 PF08159.12 GAP82854.1 - 1.9e-15 56.3 12.7 3.5e-14 52.3 0.7 3.7 3 1 0 3 3 3 2 NUC153 domain PLDc_2 PF13091.6 GAP82855.1 - 8e-17 61.4 0.4 1.6e-06 28.0 0.0 4.1 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 GAP82855.1 - 1.9e-11 43.6 2.6 5e-05 23.3 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Thioredoxin PF00085.20 GAP82856.1 - 2.8e-43 146.1 0.0 1.3e-24 86.2 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 GAP82856.1 - 1.1e-07 32.2 3.1 0.038 14.5 0.2 4.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 GAP82856.1 - 4.7e-07 29.9 0.0 0.045 13.6 0.0 4.2 3 1 1 4 4 4 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAP82856.1 - 2e-06 28.0 0.4 0.099 13.0 0.0 3.8 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 GAP82856.1 - 0.00018 21.5 0.6 0.1 12.5 0.0 3.7 4 0 0 4 4 4 1 AhpC/TSA family 7TM_GPCR_Srh PF10318.9 GAP82856.1 - 0.0055 15.8 0.1 0.0095 15.0 0.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh Thioredoxin_7 PF13899.6 GAP82856.1 - 0.0073 16.5 0.8 0.049 13.8 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 GAP82856.1 - 0.037 14.1 0.1 0.45 10.6 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin domain OST3_OST6 PF04756.13 GAP82856.1 - 0.046 13.1 0.0 5.5 6.2 0.0 2.5 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family RR_TM4-6 PF06459.12 GAP82856.1 - 2.4 7.9 5.2 0.89 9.3 2.2 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 UBN_AB PF14075.6 GAP82856.1 - 4.3 7.0 6.4 0.15 11.8 0.2 1.6 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Thioredoxin_4 PF13462.6 GAP82856.1 - 7.1 6.8 5.8 1.9 8.6 0.4 2.6 3 0 0 3 3 3 0 Thioredoxin Tyr-DNA_phospho PF06087.12 GAP82857.1 - 4.2e-147 490.5 0.0 4.9e-147 490.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase 2OG-FeII_Oxy_4 PF13661.6 GAP82857.1 - 0.058 14.1 1.5 1.2 9.8 0.1 2.9 2 1 1 3 3 3 0 2OG-Fe(II) oxygenase superfamily PRIMA1 PF16101.5 GAP82857.1 - 0.29 11.2 9.9 0.57 10.2 9.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 GAP82857.1 - 1.4 9.0 6.7 2.8 8.0 6.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 GAP82857.1 - 4.6 6.6 11.3 0.65 9.4 7.3 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ACBP PF00887.19 GAP82859.1 - 4.2e-18 65.3 0.2 5.3e-18 65.0 0.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Pyr_redox_2 PF07992.14 GAP82860.1 - 3.5e-33 115.1 5.1 5.7e-33 114.4 4.2 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP82860.1 - 4.1e-08 33.7 0.5 3.4e-05 24.3 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 GAP82860.1 - 0.13 11.6 0.1 0.3 10.4 0.1 1.5 1 0 0 1 1 1 0 ThiF family EF-hand_4 PF12763.7 GAP82861.1 - 1.1e-47 160.2 0.0 2.1e-47 159.4 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 GAP82861.1 - 1.2e-47 162.7 0.1 1.7e-47 162.2 0.1 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.32 GAP82861.1 - 1.3e-06 27.5 0.2 1.3e-06 27.5 0.2 2.3 3 0 0 3 3 2 1 EF hand EF-hand_7 PF13499.6 GAP82861.1 - 1.8e-05 25.1 0.3 8.2e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GAP82861.1 - 0.0017 18.2 0.1 0.0037 17.1 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAP82861.1 - 0.0024 17.7 0.4 0.0099 15.7 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 GAP82861.1 - 0.032 13.7 3.6 0.052 13.1 0.1 2.7 2 0 0 2 2 2 0 EF hand TPR_MLP1_2 PF07926.12 GAP82861.1 - 0.068 13.2 2.9 6.4 6.8 0.1 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 GAP82861.1 - 0.068 12.5 0.8 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 GAP82861.1 - 0.08 12.8 2.5 5.5 6.8 0.1 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 CSN5_C PF18323.1 GAP82861.1 - 0.11 13.5 0.2 0.37 11.7 0.2 2.0 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Laminin_II PF06009.12 GAP82861.1 - 0.16 12.0 0.2 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Laminin Domain II COG2 PF06148.11 GAP82861.1 - 0.18 11.9 0.6 1.2 9.3 0.1 2.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.11 GAP82861.1 - 0.29 11.4 1.4 5.3 7.3 0.1 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DHR10 PF18595.1 GAP82861.1 - 0.78 9.8 6.9 2 8.5 0.2 2.9 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain TolA_bind_tri PF16331.5 GAP82861.1 - 3.2 7.9 7.5 1.7 8.7 1.0 3.4 4 0 0 4 4 4 0 TolA binding protein trimerisation TSC22 PF01166.18 GAP82861.1 - 3.7 7.9 6.3 21 5.5 0.3 3.5 4 0 0 4 4 4 0 TSC-22/dip/bun family GFO_IDH_MocA PF01408.22 GAP82862.1 - 6.7e-17 62.4 0.0 2e-16 60.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 GAP82862.1 - 0.091 13.4 0.1 0.18 12.4 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain HET PF06985.11 GAP82865.1 - 8e-20 71.7 0.0 7.3e-19 68.6 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Flavodoxin_2 PF02525.17 GAP82866.1 - 1.4e-55 188.1 0.0 1.7e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 GAP82866.1 - 2.1e-13 50.3 0.0 4.3e-13 49.3 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase H_lectin PF09458.10 GAP82867.1 - 4.2e-19 68.5 1.7 7.3e-19 67.7 1.7 1.4 1 0 0 1 1 1 1 H-type lectin domain Lamprin PF06403.11 GAP82867.1 - 0.043 13.8 4.8 0.066 13.2 4.8 1.2 1 0 0 1 1 1 0 Lamprin DUF5488 PF17590.2 GAP82868.1 - 1.5 8.6 4.1 0.66 9.8 0.2 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5488) HET PF06985.11 GAP82871.1 - 1.5e-34 119.5 0.1 3.3e-34 118.3 0.0 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Goodbye PF17109.5 GAP82873.1 - 6.3e-21 75.1 1.3 2.5e-20 73.1 0.0 2.9 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain Methyltransf_11 PF08241.12 GAP82874.1 - 4e-11 43.4 0.0 8.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP82874.1 - 2.3e-09 37.8 0.0 7e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP82874.1 - 4.6e-05 23.3 0.0 7.6e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP82874.1 - 0.0067 17.1 0.0 0.014 16.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP82874.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Dynamin_N PF00350.23 GAP82875.1 - 2e-32 112.6 0.1 3.7e-32 111.7 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 GAP82875.1 - 9e-19 67.8 0.1 1.8e-16 60.2 0.0 2.3 1 1 1 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 GAP82875.1 - 2e-05 24.6 0.2 0.00019 21.5 0.1 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 GAP82875.1 - 0.0052 17.0 0.7 1.9 8.8 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Nucleoporin_FG PF13634.6 GAP82875.1 - 0.0071 17.2 70.8 0.07 14.0 40.0 4.0 1 1 1 2 2 1 1 Nucleoporin FG repeat region AAA_16 PF13191.6 GAP82875.1 - 0.0089 16.4 0.1 0.15 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 GAP82875.1 - 0.012 15.4 0.0 0.047 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system GED PF02212.18 GAP82875.1 - 0.061 13.5 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Dynamin GTPase effector domain AAA_15 PF13175.6 GAP82875.1 - 0.09 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 GAP82875.1 - 0.098 12.4 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 GAP82875.1 - 0.13 11.8 0.0 15 5.1 0.1 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B Esterase_phd PF10503.9 GAP82876.1 - 6.1e-25 88.0 2.0 1.1e-24 87.2 2.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Methyltransf_2 PF00891.18 GAP82876.1 - 1.7e-20 73.3 0.0 3e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Peptidase_S9 PF00326.21 GAP82876.1 - 2.6e-05 23.8 3.2 2.8e-05 23.7 0.9 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 GAP82876.1 - 0.051 12.5 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Methyltransf_25 PF13649.6 GAP82878.1 - 3.6e-10 40.4 0.1 6.7e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP82878.1 - 2.7e-08 34.4 0.0 4.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP82878.1 - 6.9e-08 33.1 0.0 1.2e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP82878.1 - 1.1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP82878.1 - 4.9e-05 22.9 0.0 7.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_33 PF10017.9 GAP82878.1 - 8.7e-05 21.8 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_23 PF13489.6 GAP82878.1 - 0.00014 21.7 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP82878.1 - 0.0026 17.1 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 GAP82878.1 - 0.0038 17.2 0.0 0.0059 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 GAP82878.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.12 GAP82878.1 - 0.02 14.0 0.0 0.47 9.5 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase PCMT PF01135.19 GAP82878.1 - 0.026 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_7 PF03492.15 GAP82878.1 - 0.029 13.6 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Methyltransf_2 PF00891.18 GAP82878.1 - 0.13 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_5 PF01795.19 GAP82878.1 - 0.21 11.0 0.0 0.27 10.7 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family SPX PF03105.19 GAP82879.1 - 0.16 11.8 6.2 0.2 11.5 6.2 1.1 1 0 0 1 1 1 0 SPX domain IMUP PF15761.5 GAP82879.1 - 1.8 9.3 13.6 15 6.3 9.5 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein SR-25 PF10500.9 GAP82879.1 - 3.6 7.1 11.2 5.8 6.4 11.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein YchF-GTPase_C PF06071.13 GAP82880.1 - 1.1e-34 118.5 0.6 3e-34 117.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 GAP82880.1 - 5.4e-17 61.9 0.0 5.9e-16 58.6 0.0 2.2 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAP82880.1 - 0.00087 18.9 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 GAP82880.1 - 0.0016 18.4 0.1 0.004 17.2 0.1 1.7 1 0 0 1 1 1 1 TGS domain AAA_18 PF13238.6 GAP82880.1 - 0.042 14.4 0.1 17 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Ribosomal_L21p PF00829.21 GAP82880.1 - 1.8 8.9 5.2 17 5.8 2.1 2.4 2 0 0 2 2 2 0 Ribosomal prokaryotic L21 protein Peptidase_C97 PF05903.14 GAP82881.1 - 5.3e-34 117.2 0.0 6.9e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 GAP82881.1 - 0.00095 19.5 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.12 GAP82881.1 - 0.1 13.0 0.3 0.26 11.6 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Med10 PF09748.9 GAP82882.1 - 0.00011 22.1 0.1 0.00013 22.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Ribosomal_S11 PF00411.19 GAP82883.1 - 1.5e-11 44.6 0.0 2.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.15 GAP82884.1 - 2.9e-37 128.0 0.0 1e-36 126.2 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain DUF913 PF06025.12 GAP82884.1 - 1.4 7.9 3.7 2.4 7.1 3.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Plasmodium_Vir PF05795.11 GAP82884.1 - 9.4 5.5 11.4 16 4.8 11.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1768 PF08719.11 GAP82885.1 - 1.9e-52 177.7 0.0 2.4e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) GCP_N_terminal PF17681.1 GAP82890.1 - 5.5e-25 88.6 0.0 8.1e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAP82890.1 - 2.8e-22 79.6 0.0 5.1e-22 78.7 0.0 1.4 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Senescence PF06911.12 GAP82891.1 - 1.4e-56 191.7 3.7 2.7e-56 190.8 3.7 1.5 1 0 0 1 1 1 1 Senescence-associated protein Fungal_trans PF04082.18 GAP82892.1 - 7.1e-18 64.6 0.0 1.4e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP82892.1 - 1.8e-07 31.1 9.4 4.9e-07 29.8 9.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 GAP82892.1 - 0.19 11.7 11.0 0.32 11.0 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 GAP82892.1 - 8.9 5.0 5.7 43 2.7 4.8 2.0 2 0 0 2 2 2 0 Presenilin Peptidase_S28 PF05577.12 GAP82894.1 - 4.1e-55 187.3 0.0 5.5e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 SgrT PF15894.5 GAP82895.1 - 0.36 10.8 3.4 23 5.1 0.1 3.1 3 0 0 3 3 3 0 Inhibitor of glucose uptake transporter SgrT MFS_1 PF07690.16 GAP82896.1 - 3.5e-06 26.2 28.5 3.7e-06 26.1 25.2 2.2 1 1 2 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.16 GAP82896.1 - 1.6e-05 24.7 3.7 2e-05 24.3 2.8 1.7 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF2537 PF10801.8 GAP82896.1 - 6.5 7.0 18.4 1.6 9.0 2.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2537) BSP PF04450.12 GAP82898.1 - 1.2e-66 224.5 0.0 1.4e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria CLASP_N PF12348.8 GAP82899.1 - 1.7e-134 446.5 0.0 7.2e-89 297.2 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 GAP82899.1 - 2.6e-05 24.1 0.6 13 6.4 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 GAP82899.1 - 0.00051 20.1 0.3 0.018 15.1 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAP82899.1 - 0.073 11.6 1.2 4.6 5.7 0.0 3.2 4 1 0 5 5 5 0 Adaptin N terminal region FR47 PF08445.10 GAP82900.1 - 5.1e-07 29.6 0.2 1.4e-06 28.2 0.1 1.8 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_10 PF13673.7 GAP82900.1 - 1.6e-06 28.0 0.0 2.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP82900.1 - 4.9e-06 26.8 0.0 5.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP82900.1 - 0.0011 19.4 0.0 0.0016 18.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP82900.1 - 0.048 13.7 0.0 0.13 12.4 0.0 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Beta-TrCP_D PF12125.8 GAP82900.1 - 0.25 11.3 0.1 0.41 10.6 0.1 1.3 1 0 0 1 1 1 0 D domain of beta-TrCP Ribonuclease_T2 PF00445.18 GAP82901.1 - 5e-32 111.6 0.0 6.5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Sec62 PF03839.16 GAP82903.1 - 1.7e-73 246.7 0.9 1.7e-73 246.7 0.9 1.4 2 0 0 2 2 2 1 Translocation protein Sec62 HicB PF05534.12 GAP82903.1 - 0.12 12.2 0.2 1 9.3 0.1 2.2 2 0 0 2 2 2 0 HicB family Corona_M PF01635.18 GAP82903.1 - 0.23 10.7 7.0 0.36 10.1 7.0 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein His_Phos_2 PF00328.22 GAP82905.1 - 2.5e-63 214.7 0.0 3e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PsbY PF06298.11 GAP82906.1 - 0.14 12.1 5.3 0.3 11.0 5.3 1.5 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) FeoB_associated PF12669.7 GAP82906.1 - 0.56 10.6 1.3 0.93 9.9 1.3 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein TFIIE_alpha PF02002.17 GAP82907.1 - 0.039 13.8 0.1 0.051 13.4 0.1 1.1 1 0 0 1 1 1 0 TFIIE alpha subunit UbiA PF01040.18 GAP82908.1 - 1.7e-36 125.8 15.9 2.2e-36 125.5 15.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 GAP82909.1 - 3.2e-43 148.1 0.0 4.1e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 GAP82911.1 - 4.7e-30 104.5 0.0 8e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAP82911.1 - 1.1e-28 100.1 0.0 1.8e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 GAP82911.1 - 3.9e-11 43.1 0.1 1e-10 41.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 GAP82911.1 - 4.8e-10 39.3 0.0 9.1e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAP82911.1 - 0.032 14.1 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 KR domain ATP-cone PF03477.16 GAP82911.1 - 0.23 12.0 0.0 0.51 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP cone domain Voldacs PF03517.13 GAP82912.1 - 1.1e-08 35.2 0.0 1.3e-08 35.1 0.0 1.0 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Transp_cyt_pur PF02133.15 GAP82913.1 - 1e-140 469.4 35.0 1.2e-140 469.2 35.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PARP PF00644.20 GAP82914.1 - 4.7e-46 156.9 1.8 3.7e-45 153.9 0.0 2.7 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 GAP82914.1 - 7.6e-43 145.9 0.6 1.3e-42 145.1 0.6 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 GAP82914.1 - 2.7e-22 78.6 1.3 6.1e-22 77.5 1.3 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 GAP82914.1 - 2.6e-13 50.1 0.0 4.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAP82914.1 - 0.00069 20.0 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 GAP82914.1 - 0.00084 19.2 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 GAP82914.1 - 0.0074 16.6 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 GAP82914.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain TFIIA PF03153.13 GAP82915.1 - 0.0043 17.1 34.5 0.0044 17.1 34.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 GAP82915.1 - 0.026 13.3 24.0 0.027 13.2 24.0 1.0 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 GAP82915.1 - 0.21 9.8 33.8 0.21 9.8 33.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 GAP82915.1 - 0.45 7.6 17.2 0.48 7.5 17.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GAGA_bind PF06217.12 GAP82915.1 - 0.51 10.6 16.9 0.57 10.4 16.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Raftlin PF15250.6 GAP82915.1 - 0.56 8.9 14.6 0.6 8.8 14.6 1.1 1 0 0 1 1 1 0 Raftlin Lin-8 PF03353.15 GAP82915.1 - 1.5 8.3 24.9 1.7 8.1 24.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MDM10 PF12519.8 GAP82915.1 - 1.9 7.3 16.6 2 7.2 16.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Membralin PF09746.9 GAP82915.1 - 1.9 7.4 9.3 2 7.4 9.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Asp-B-Hydro_N PF05279.11 GAP82915.1 - 1.9 8.5 19.3 2.1 8.3 19.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RR_TM4-6 PF06459.12 GAP82915.1 - 2.4 7.9 24.8 3.1 7.5 24.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MMR1 PF08505.10 GAP82915.1 - 2.6 8.3 26.0 3.3 7.9 26.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Zip PF02535.22 GAP82915.1 - 2.8 7.1 14.8 3.1 6.9 14.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Gti1_Pac2 PF09729.9 GAP82915.1 - 4 7.5 18.2 5.8 7.0 18.2 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 GAP82915.1 - 5.3 6.0 22.9 6.2 5.7 22.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Endostatin PF06482.11 GAP82915.1 - 7.2 6.0 20.8 8.7 5.7 20.8 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Dicty_REP PF05086.12 GAP82915.1 - 7.4 4.4 16.4 8.4 4.2 16.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_memb PF02932.16 GAP82915.1 - 8.1 6.4 18.3 10 6.1 18.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 GAP82915.1 - 8.3 6.4 18.3 12 5.9 18.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SPT2 PF08243.11 GAP82916.1 - 2.3e-09 37.7 26.5 2.9e-09 37.4 12.9 2.6 1 1 1 2 2 2 2 SPT2 chromatin protein Ribosomal_60s PF00428.19 GAP82918.1 - 4.6e-27 94.4 9.3 5.3e-27 94.2 9.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 GAP82918.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain RibD_C PF01872.17 GAP82918.1 - 0.095 12.5 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain Paramyxo_C PF01692.18 GAP82918.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C Cytomega_UL84 PF06284.11 GAP82918.1 - 0.22 9.9 1.5 0.25 9.8 1.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Pkinase PF00069.25 GAP82919.1 - 3.7e-45 154.4 0.0 6.6e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP82919.1 - 7e-19 68.1 0.0 1.9e-18 66.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP82919.1 - 0.00025 21.1 0.0 0.074 13.0 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 GAP82919.1 - 0.008 15.8 0.3 0.094 12.3 0.0 2.1 2 0 0 2 2 2 1 RIO1 family PsaA_PsaB PF00223.19 GAP82919.1 - 0.22 9.7 0.0 0.32 9.1 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribosomal_L21p PF00829.21 GAP82920.1 - 1e-13 51.4 0.0 1.3e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DEC-1_N PF04625.13 GAP82920.1 - 6.4 5.7 9.7 8.7 5.2 9.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NUFIP1 PF10453.9 GAP82921.1 - 3.9e-07 29.8 0.3 1.1e-06 28.4 0.3 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) HrpB7 PF09486.10 GAP82921.1 - 0.0097 16.3 0.8 0.017 15.5 0.8 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) MMU163 PF17119.5 GAP82921.1 - 0.21 10.7 1.4 0.52 9.4 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial protein up-regulated during meiosis zf_CCCH_4 PF18345.1 GAP82921.1 - 0.39 10.8 8.9 0.75 9.9 8.9 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 GAP82921.1 - 0.45 10.5 7.3 0.88 9.6 7.3 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RNA_pol_Rbc25 PF08292.12 GAP82922.1 - 9.9e-27 93.7 4.5 7.6e-26 90.9 4.5 2.1 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 GAP82922.1 - 2.5e-16 59.8 0.0 4.7e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 EMC3_TMCO1 PF01956.16 GAP82923.1 - 1.1e-49 168.5 3.2 1.4e-49 168.1 3.2 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 GAP82924.1 - 6.2e-54 182.2 0.1 7.8e-54 181.8 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Glyco_hydro_3_C PF01915.22 GAP82925.1 - 0.0018 18.3 0.0 0.002 18.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain MMS19_N PF14500.6 GAP82926.1 - 1.2e-36 126.7 2.2 2.5e-35 122.3 0.9 3.2 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 GAP82926.1 - 3.4e-12 46.2 0.3 4.3e-11 42.6 0.0 2.7 2 1 0 3 3 3 1 RNAPII transcription regulator C-terminal THF_DHG_CYH PF00763.23 GAP82927.1 - 9.9e-26 90.3 0.0 1.5e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 GAP82927.1 - 8.4e-14 51.2 0.0 2.2e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.22 GAP82927.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Ank_2 PF12796.7 GAP82928.1 - 1.1e-38 131.7 0.2 6.4e-14 52.3 0.0 8.5 9 1 1 10 10 10 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP82928.1 - 7.5e-29 96.6 7.0 0.00042 20.5 0.0 11.2 13 0 0 13 13 13 6 Ankyrin repeat Ank_4 PF13637.6 GAP82928.1 - 3.7e-27 94.3 0.1 0.00026 21.5 0.1 9.0 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP82928.1 - 6.2e-26 90.1 0.4 0.00077 19.7 0.1 9.5 8 1 1 9 9 9 4 Ankyrin repeats (many copies) Ank PF00023.30 GAP82928.1 - 2.6e-22 78.2 7.5 0.00017 21.8 0.0 9.8 10 0 0 10 10 10 4 Ankyrin repeat GlutR_dimer PF00745.20 GAP82928.1 - 0.097 13.1 3.0 5.4 7.5 2.0 3.2 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain CENP-C_C PF11699.8 GAP82929.1 - 0.02 15.1 0.1 0.02 15.1 0.1 1.0 1 0 0 1 1 1 0 Mif2/CENP-C like DUF1100 PF06500.11 GAP82930.1 - 2.3e-12 46.5 0.0 4.8e-12 45.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 GAP82930.1 - 6.6e-06 26.0 0.0 0.00092 18.9 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAP82930.1 - 0.00092 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 GAP82930.1 - 0.0016 18.1 0.0 0.0051 16.5 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 GAP82930.1 - 0.0018 17.9 0.0 0.004 16.8 0.1 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 GAP82930.1 - 0.0018 17.8 0.0 0.0044 16.5 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 GAP82930.1 - 0.0027 16.4 0.0 0.71 8.5 0.0 2.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 GAP82930.1 - 0.0047 16.2 0.0 0.0093 15.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S10 PF00450.22 GAP82931.1 - 4.9e-67 227.2 0.0 5.6e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase ADH_N PF08240.12 GAP82932.1 - 4.8e-24 84.3 5.0 7.7e-24 83.7 5.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP82932.1 - 3.3e-20 72.4 0.1 5.6e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP82932.1 - 9.3e-07 30.0 0.0 1.6e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAP82932.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAP82932.1 - 0.019 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PolyA_pol PF01743.20 GAP82933.1 - 2.9e-19 69.7 0.0 6.5e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 GAP82933.1 - 0.00059 19.5 0.1 0.0015 18.3 0.1 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF742 PF05331.11 GAP82933.1 - 0.03 14.1 0.1 0.27 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF742) Glycos_transf_4 PF00953.21 GAP82934.1 - 7.3e-33 113.8 12.4 7.3e-33 113.8 12.4 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 4 Suf PF05843.14 GAP82935.1 - 0.028 14.4 1.7 0.039 13.9 1.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.9 GAP82935.1 - 0.037 14.3 12.9 0.083 13.2 12.9 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA tRNA_lig_CPD PF08302.11 GAP82935.1 - 0.05 13.0 1.2 0.071 12.5 1.2 1.1 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Spt20 PF12090.8 GAP82935.1 - 0.08 12.6 12.1 0.1 12.2 12.1 1.2 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 GAP82935.1 - 0.97 8.1 4.1 1.1 7.9 4.1 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 GAP82935.1 - 1 9.3 19.6 1.3 9.0 19.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Chorion_2 PF03964.15 GAP82935.1 - 1.2 10.0 19.5 0.32 11.8 14.6 2.4 2 0 0 2 2 2 0 Chorion family 2 BAF1_ABF1 PF04684.13 GAP82935.1 - 1.7 7.6 6.5 2.2 7.3 6.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.13 GAP82935.1 - 2 9.1 15.2 3.2 8.4 15.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.7 GAP82935.1 - 7.4 4.6 6.7 9.3 4.2 6.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med3 PF11593.8 GAP82935.1 - 8.3 5.5 20.4 13 4.8 20.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PHD PF00628.29 GAP82939.1 - 4.9e-07 29.5 9.4 1e-06 28.5 9.4 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 GAP82939.1 - 2.1e-05 25.0 0.0 9.3e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 SET domain GMC_oxred_N PF00732.19 GAP82940.1 - 5e-51 173.8 0.1 1.2e-50 172.5 0.1 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP82940.1 - 1.4e-28 100.3 0.0 2.3e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Amidase PF01425.21 GAP82941.1 - 1.8e-70 238.1 0.8 1.7e-67 228.4 0.1 2.3 2 1 0 2 2 2 2 Amidase NAT PF04768.13 GAP82942.1 - 1.1e-48 165.1 0.0 6.8e-48 162.5 0.0 2.0 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase HSP70 PF00012.20 GAP82943.1 - 1.2e-173 578.6 8.5 5e-173 576.5 8.5 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAP82943.1 - 4.6e-12 45.4 0.0 4e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.20 GAP82943.1 - 0.084 12.3 0.0 0.26 10.7 0.0 2.1 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Apolipoprotein PF01442.18 GAP82943.1 - 0.089 12.7 12.8 0.12 12.2 7.8 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3987 PF13148.6 GAP82943.1 - 3.6 6.5 13.3 14 4.5 9.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) GTP_EFTU PF00009.27 GAP82944.1 - 1.8e-33 115.7 0.0 6.9e-33 113.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAP82944.1 - 2.3e-19 69.5 0.0 5.4e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 GAP82944.1 - 8.9e-09 35.6 8.7 1.3e-06 28.7 0.5 3.7 4 0 0 4 4 4 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 GAP82944.1 - 1e-08 34.9 2.0 1.6e-08 34.4 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 GAP82944.1 - 1.5e-07 31.5 0.3 7.9e-06 25.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 GAP82944.1 - 0.00023 21.4 0.0 0.00059 20.1 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 GAP82944.1 - 0.0071 16.2 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 GAP82944.1 - 0.06 13.0 0.0 0.36 10.4 0.0 2.4 1 1 0 1 1 1 0 Ras family TrkA_C PF02080.21 GAP82944.1 - 0.17 11.8 0.5 11 5.9 0.0 2.6 2 0 0 2 2 2 0 TrkA-C domain HET PF06985.11 GAP82945.1 - 6.4e-26 91.4 0.0 1.1e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MMS1_N PF10433.9 GAP82946.1 - 1.2e-57 195.7 0.0 3.8e-57 194.0 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term APH PF01636.23 GAP82947.1 - 2.7e-10 40.6 0.0 4.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 GAP82948.1 - 7.4e-19 68.3 0.0 9.6e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Vps52 PF04129.12 GAP82949.1 - 3.5e-120 402.2 0.0 4.6e-120 401.8 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 GAP82949.1 - 2.9e-06 26.0 1.0 6.2e-06 24.9 1.0 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.10 GAP82949.1 - 0.0048 16.7 0.1 0.26 11.1 0.0 2.6 3 0 0 3 3 3 1 Mer2 Spc7 PF08317.11 GAP82949.1 - 0.017 14.0 0.2 0.029 13.2 0.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 GAP82949.1 - 0.079 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IMUP PF15761.5 GAP82949.1 - 0.54 11.0 1.9 1.2 9.9 1.9 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein THOC7 PF05615.13 GAP82949.1 - 0.73 10.1 3.1 0.94 9.8 1.0 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 eIF-5a PF01287.20 GAP82950.1 - 3e-16 59.3 0.2 4.4e-16 58.7 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 GAP82950.1 - 0.00023 21.1 0.3 0.0061 16.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain zf-RRN7 PF11781.8 GAP82951.1 - 8.7e-05 22.1 3.2 0.00015 21.4 3.2 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 CARMIL_C PF16000.5 GAP82951.1 - 0.011 15.4 0.3 0.017 14.8 0.3 1.3 1 0 0 1 1 1 0 CARMIL C-terminus DUF35_N PF12172.8 GAP82951.1 - 0.023 14.6 0.4 0.051 13.5 0.4 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) ubiquitin PF00240.23 GAP82952.1 - 8.3e-34 115.2 0.6 1.1e-33 114.7 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 GAP82952.1 - 2.8e-31 107.1 9.9 5.6e-31 106.2 9.9 1.5 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 GAP82952.1 - 1.3e-15 57.0 0.7 1.8e-15 56.5 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAP82952.1 - 3.3e-05 24.3 0.2 0.00011 22.5 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAP82952.1 - 0.0048 16.8 0.1 0.007 16.3 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAP82952.1 - 0.0068 16.7 0.1 0.011 16.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAP82952.1 - 0.015 15.4 0.0 0.043 13.9 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAP82952.1 - 0.052 14.1 0.0 0.076 13.6 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAP82952.1 - 0.11 12.5 1.2 12 6.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Eaf7 PF07904.13 GAP82953.1 - 8.9e-24 83.9 0.1 8.9e-24 83.9 0.1 2.9 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 Nop14 PF04147.12 GAP82953.1 - 0.042 12.1 33.8 0.056 11.7 33.8 1.2 1 0 0 1 1 1 0 Nop14-like family CNDH2_C PF16858.5 GAP82953.1 - 0.094 12.6 17.3 0.16 11.8 17.3 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RhoGEF67_u1 PF16615.5 GAP82953.1 - 0.11 13.0 3.6 0.46 11.0 3.6 2.0 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 Merozoite_SPAM PF07133.11 GAP82953.1 - 0.52 10.3 37.5 0.89 9.5 37.5 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Na_trans_assoc PF06512.13 GAP82953.1 - 0.99 9.7 24.0 2 8.7 24.0 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated PPP4R2 PF09184.11 GAP82953.1 - 1 8.9 37.1 0.075 12.6 32.2 1.6 2 0 0 2 2 2 0 PPP4R2 API5 PF05918.11 GAP82953.1 - 2.5 6.8 9.5 3.6 6.3 9.5 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GCP_C_terminal PF04130.13 GAP82954.1 - 2.4e-77 260.4 1.9 2.5e-77 260.4 0.0 1.9 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAP82954.1 - 1.4e-24 87.3 0.0 2.3e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DASH_Ask1 PF08655.10 GAP82955.1 - 2.7e-30 104.0 0.2 4.1e-30 103.5 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 NKAP PF15692.5 GAP82955.1 - 1.3 9.8 4.8 0.27 12.0 0.8 2.0 2 0 0 2 2 2 0 NF-kappa-B-activating protein Codanin-1_C PF15296.6 GAP82956.1 - 0.11 12.6 1.9 0.16 12.1 0.4 1.8 1 1 1 2 2 2 0 Codanin-1 C-terminus p450 PF00067.22 GAP82957.1 - 7.6e-50 170.0 0.0 1.2e-49 169.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Phage_T7_Capsid PF05396.11 GAP82957.1 - 0.17 12.3 0.0 0.52 10.7 0.0 1.8 2 0 0 2 2 2 0 Phage T7 capsid assembly protein LCM PF04072.14 GAP82959.1 - 1.6e-22 80.3 0.0 5.1e-22 78.7 0.0 1.8 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Mito_carr PF00153.27 GAP82960.1 - 0.0052 16.7 0.4 4.5 7.3 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial carrier protein AurF PF11583.8 GAP82960.1 - 0.049 12.9 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF TFIID-18kDa PF02269.16 GAP82961.1 - 3e-27 94.5 0.9 4.1e-26 90.8 0.1 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 GAP82961.1 - 0.025 14.9 0.3 0.81 10.0 0.1 2.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sporozoite_P67 PF05642.11 GAP82961.1 - 0.092 10.8 0.2 0.094 10.8 0.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3313 PF11769.8 GAP82961.1 - 0.096 12.5 0.0 0.24 11.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3313) NACHT PF05729.12 GAP82962.1 - 4.2e-09 36.6 0.0 8.6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 GAP82962.1 - 1.9e-07 30.6 1.4 2.6e-06 26.9 1.4 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 GAP82962.1 - 2.9e-06 27.8 0.0 7.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP82962.1 - 6.9e-06 26.4 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ank_2 PF12796.7 GAP82962.1 - 0.0026 18.3 0.0 0.026 15.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) KAP_NTPase PF07693.14 GAP82962.1 - 0.028 13.6 0.2 0.27 10.4 0.0 2.3 3 0 0 3 3 3 0 KAP family P-loop domain YugN PF08868.10 GAP82962.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 YugN-like family AAA PF00004.29 GAP82962.1 - 0.12 12.7 0.0 0.8 10.1 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Neprosin PF03080.15 GAP82964.1 - 3.8e-43 147.4 7.4 4.3e-43 147.2 7.4 1.0 1 0 0 1 1 1 1 Neprosin BA14K PF07886.11 GAP82964.1 - 2.3 8.2 7.0 5.7 6.9 0.9 2.6 2 0 0 2 2 2 0 BA14K-like protein HET PF06985.11 GAP82965.1 - 1.1e-25 90.7 0.0 1.9e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 GAP82966.1 - 7.5e-40 136.5 0.1 1.2e-39 135.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP82966.1 - 1.5e-26 93.4 0.5 2e-26 93.0 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 GAP82966.1 - 5.5e-07 29.7 0.2 9.3e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 GAP82966.1 - 9.1e-06 25.7 0.4 2.3e-05 24.4 0.4 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP82966.1 - 4.1e-05 23.1 0.1 0.00021 20.8 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAP82966.1 - 0.0062 16.1 0.0 0.024 14.2 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family ADH_zinc_N PF00107.26 GAP82966.1 - 0.018 15.0 0.2 0.038 14.0 0.2 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PP2C_2 PF13672.6 GAP82966.1 - 0.032 13.9 0.1 0.065 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C Tim44 PF04280.15 GAP82966.1 - 0.15 12.2 0.0 0.46 10.6 0.0 1.8 2 0 0 2 2 2 0 Tim44-like domain TetR_C_6 PF13977.6 GAP82966.1 - 0.37 11.0 3.1 3 8.1 0.0 2.6 3 0 0 3 3 3 0 BetI-type transcriptional repressor, C-terminal adh_short_C2 PF13561.6 GAP82967.1 - 1.4e-44 152.5 4.9 4.4e-35 121.3 4.9 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP82967.1 - 1.2e-41 142.3 1.4 1.5e-41 142.0 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP82967.1 - 9.7e-10 38.6 1.4 1.5e-09 38.0 1.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAP82967.1 - 0.0032 17.4 1.5 0.0051 16.7 1.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 GAP82967.1 - 0.017 15.2 0.4 0.03 14.4 0.4 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAP82967.1 - 0.027 13.8 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAP82967.1 - 0.07 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 GAP82967.1 - 0.08 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.14 GAP82967.1 - 0.19 11.3 0.2 0.34 10.5 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glycos_transf_2 PF00535.26 GAP82968.1 - 1.8e-33 115.7 0.0 2.1e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAP82968.1 - 3.6e-11 43.4 0.0 4.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 GAP82968.1 - 0.00033 20.2 0.0 0.00043 19.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAP82968.1 - 0.00065 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Ank_2 PF12796.7 GAP82969.1 - 6.1e-63 209.4 7.5 7.3e-12 45.7 0.1 7.8 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP82969.1 - 8.7e-58 192.0 2.5 1.6e-08 34.9 0.1 9.8 7 2 3 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP82969.1 - 7.3e-40 134.5 9.4 3e-06 27.4 0.0 11.5 4 3 8 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP82969.1 - 2.8e-38 125.5 1.6 0.0025 18.2 0.0 14.1 14 0 0 14 14 14 7 Ankyrin repeat Ank PF00023.30 GAP82969.1 - 1.1e-31 107.8 14.9 0.0001 22.6 0.0 13.0 14 0 0 14 14 14 7 Ankyrin repeat HeLo PF14479.6 GAP82969.1 - 2e-16 60.4 0.0 9.1e-13 48.5 0.0 2.5 2 0 0 2 2 2 2 Prion-inhibition and propagation NACHT PF05729.12 GAP82969.1 - 4.6e-11 42.9 0.0 1.2e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAP82969.1 - 0.00013 22.3 0.0 0.00048 20.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAP82969.1 - 0.0025 18.2 0.0 0.025 15.0 0.0 2.4 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP82969.1 - 0.0033 17.8 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain NB-ARC PF00931.22 GAP82969.1 - 0.031 13.5 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 GAP82969.1 - 0.046 13.7 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAP82969.1 - 0.13 12.6 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ZZ PF00569.17 GAP82969.1 - 0.22 11.4 5.3 0.5 10.2 5.3 1.7 1 0 0 1 1 1 0 Zinc finger, ZZ type C1_2 PF03107.16 GAP82969.1 - 6.4 7.2 11.0 13 6.2 11.0 1.5 1 0 0 1 1 1 0 C1 domain PfkB PF00294.24 GAP82970.1 - 2.6e-14 53.3 0.0 4.2e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HET PF06985.11 GAP82971.1 - 3.6e-32 111.7 0.0 5.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Isochorismatase PF00857.20 GAP82972.1 - 1e-38 133.2 0.1 1.2e-38 133.0 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family TFR_dimer PF04253.15 GAP82974.1 - 2.2e-33 114.9 0.0 4e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 GAP82974.1 - 1.3e-15 57.6 0.0 2.1e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAP82974.1 - 2.3e-11 43.5 0.1 5.7e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 GAP82974.1 - 0.046 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Vps35 PF03635.17 GAP82975.1 - 0 1029.5 0.0 0 1029.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 HET PF06985.11 GAP82977.1 - 1.5e-27 96.8 0.0 2.3e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1664 PF07889.12 GAP82978.1 - 4.8e-10 39.5 18.4 0.00043 20.3 2.4 4.3 1 1 3 4 4 4 3 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GAP82978.1 - 1e-08 35.4 39.9 1e-06 28.8 23.2 2.8 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 GAP82978.1 - 1.6e-08 34.6 15.3 3.2e-05 23.9 5.8 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Prominin PF05478.11 GAP82978.1 - 2.3e-05 22.6 21.1 4.1e-05 21.8 21.1 1.4 1 1 0 1 1 1 1 Prominin ApoO PF09769.9 GAP82978.1 - 2.4e-05 24.3 7.2 0.0067 16.4 1.8 3.4 1 1 1 2 2 2 1 Apolipoprotein O CdvA PF18822.1 GAP82978.1 - 2.7e-05 24.0 9.7 0.11 12.3 0.6 3.8 1 1 2 3 3 3 3 CdvA-like coiled-coil domain DUF3618 PF12277.8 GAP82978.1 - 3.1e-05 24.2 6.3 6.5 7.1 0.2 5.9 3 1 3 6 6 5 0 Protein of unknown function (DUF3618) Golgin_A5 PF09787.9 GAP82978.1 - 3.1e-05 23.6 14.6 8.9e-05 22.1 14.4 1.8 1 1 0 1 1 1 1 Golgin subfamily A member 5 DUF4677 PF15726.5 GAP82978.1 - 4.1e-05 23.8 1.6 1 9.5 0.1 3.3 1 1 3 4 4 4 1 Domain of unknown function (DUF4677) DUF3584 PF12128.8 GAP82978.1 - 5.8e-05 20.9 16.8 0.00024 18.8 16.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) HIP1_clath_bdg PF16515.5 GAP82978.1 - 7.6e-05 23.3 15.7 0.011 16.4 1.7 3.6 1 1 2 3 3 3 2 Clathrin-binding domain of Huntingtin-interacting protein 1 SoPB_HTH PF18090.1 GAP82978.1 - 0.00028 21.0 0.8 0.034 14.3 0.0 3.3 1 1 2 4 4 4 1 Centromere-binding protein HTH domain Syntaxin-6_N PF09177.11 GAP82978.1 - 0.00036 21.0 15.5 0.27 11.8 2.7 3.9 1 1 2 3 3 3 2 Syntaxin 6, N-terminal DUF883 PF05957.13 GAP82978.1 - 0.00055 20.5 8.8 0.15 12.7 0.8 3.3 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 GAP82978.1 - 0.00094 19.3 23.8 0.017 15.2 13.7 2.6 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) THOC7 PF05615.13 GAP82978.1 - 0.001 19.4 12.2 0.047 14.0 5.1 2.8 1 1 1 2 2 2 2 Tho complex subunit 7 Fzo_mitofusin PF04799.13 GAP82978.1 - 0.0019 17.8 14.8 0.063 12.8 3.6 3.4 1 1 3 4 4 4 3 fzo-like conserved region OmpH PF03938.14 GAP82978.1 - 0.0019 18.5 18.1 0.062 13.6 6.4 2.5 1 1 1 2 2 2 2 Outer membrane protein (OmpH-like) YtxH PF12732.7 GAP82978.1 - 0.0022 18.5 12.5 1.1 9.9 1.9 3.7 1 1 1 2 2 2 1 YtxH-like protein AAA_13 PF13166.6 GAP82978.1 - 0.0025 16.6 18.6 0.0032 16.2 18.6 1.1 1 0 0 1 1 1 1 AAA domain Filament PF00038.21 GAP82978.1 - 0.003 17.2 14.0 0.0065 16.1 12.3 1.9 1 1 0 1 1 1 1 Intermediate filament protein Phe_tRNA-synt_N PF02912.18 GAP82978.1 - 0.004 17.1 13.5 0.3 11.1 1.1 5.5 1 1 5 6 6 6 1 Aminoacyl tRNA synthetase class II, N-terminal domain BAR_3 PF16746.5 GAP82978.1 - 0.0044 16.8 2.3 0.0044 16.8 2.3 2.3 1 1 1 2 2 2 1 BAR domain of APPL family DUF3509 PF12021.8 GAP82978.1 - 0.0046 16.7 7.7 4.2 7.2 0.1 4.2 1 1 3 5 5 3 0 Protein of unknown function (DUF3509) RESP18 PF14948.6 GAP82978.1 - 0.0076 16.5 2.4 0.035 14.4 0.1 2.8 1 1 1 3 3 3 1 RESP18 domain Spc7 PF08317.11 GAP82978.1 - 0.0076 15.2 16.4 0.021 13.7 14.8 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein Phage_Mu_Gam PF07352.12 GAP82978.1 - 0.0088 16.0 12.3 0.46 10.4 0.6 3.5 1 1 3 4 4 4 2 Bacteriophage Mu Gam like protein TPR_MLP1_2 PF07926.12 GAP82978.1 - 0.009 16.1 7.7 0.009 16.1 7.7 2.9 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein JIP_LZII PF16471.5 GAP82978.1 - 0.0091 16.2 21.6 0.8 9.9 1.3 5.3 1 1 5 6 6 6 2 JNK-interacting protein leucine zipper II DUF1640 PF07798.11 GAP82978.1 - 0.0092 16.0 19.9 0.085 12.9 12.6 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1640) YlqD PF11068.8 GAP82978.1 - 0.01 16.2 20.4 0.046 14.1 8.6 3.2 1 1 1 2 2 2 0 YlqD protein V-SNARE PF05008.15 GAP82978.1 - 0.016 15.6 10.7 0.028 14.8 1.9 3.2 1 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Zw10 PF06248.13 GAP82978.1 - 0.02 13.5 10.8 0.027 13.1 9.4 1.7 1 1 1 2 2 2 0 Centromere/kinetochore Zw10 DUF4407 PF14362.6 GAP82978.1 - 0.02 14.3 22.0 0.043 13.2 20.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.13 GAP82978.1 - 0.023 15.1 9.7 4.9 7.5 8.5 3.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region COG2 PF06148.11 GAP82978.1 - 0.024 14.7 14.0 1.8 8.7 1.2 4.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TolA_bind_tri PF16331.5 GAP82978.1 - 0.026 14.6 24.8 0.85 9.7 0.3 6.0 2 1 4 6 6 5 0 TolA binding protein trimerisation T7SS_ESX_EspC PF10824.8 GAP82978.1 - 0.027 14.9 5.1 0.68 10.4 0.4 3.3 1 1 2 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DUF3810 PF12725.7 GAP82978.1 - 0.028 13.8 9.5 0.27 10.5 0.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3810) Tup_N PF08581.10 GAP82978.1 - 0.032 14.5 13.0 1.7 9.0 1.3 3.5 1 1 1 3 3 3 0 Tup N-terminal GldM_N PF12081.8 GAP82978.1 - 0.033 14.3 17.1 4.5 7.3 17.1 2.7 1 1 0 1 1 1 0 GldM N-terminal domain DLP_helical PF18709.1 GAP82978.1 - 0.041 13.1 18.4 0.85 8.8 5.8 2.4 1 1 1 2 2 2 0 Dynamin-like helical domain Dmd PF17587.2 GAP82978.1 - 0.062 13.6 6.1 31 5.0 0.1 4.3 1 1 2 4 4 4 0 Discriminator of mRNA degradation Baculo_p24 PF05073.12 GAP82978.1 - 0.063 13.0 22.1 0.12 12.1 7.3 2.2 1 1 1 2 2 2 0 Baculovirus P24 capsid protein PIN_8 PF18476.1 GAP82978.1 - 0.065 13.1 14.9 0.55 10.0 5.4 2.3 1 1 1 2 2 2 0 PIN like domain DUF4600 PF15372.6 GAP82978.1 - 0.084 13.3 11.2 7 7.1 3.3 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) DUF3958 PF13125.6 GAP82978.1 - 0.087 13.0 3.3 5 7.4 0.1 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Val_tRNA-synt_C PF10458.9 GAP82978.1 - 0.095 13.0 1.3 37 4.7 0.0 3.6 2 2 1 4 4 3 0 Valyl tRNA synthetase tRNA binding arm Latarcin PF10279.9 GAP82978.1 - 0.098 13.1 7.9 42 4.6 7.9 3.4 1 1 0 1 1 1 0 Latarcin precursor Histidinol_dh PF00815.20 GAP82978.1 - 0.11 11.5 8.6 0.39 9.7 4.4 2.1 1 1 1 2 2 2 0 Histidinol dehydrogenase KfrA_N PF11740.8 GAP82978.1 - 0.14 12.8 8.3 0.51 11.0 0.3 2.8 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Cortex-I_coil PF09304.10 GAP82978.1 - 0.14 12.4 9.5 0.26 11.5 3.0 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF885 PF05960.11 GAP82978.1 - 0.18 11.4 6.7 0.3 10.7 6.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) MnmE_helical PF12631.7 GAP82978.1 - 0.23 11.6 11.2 0.24 11.6 4.6 2.8 1 1 1 2 2 2 0 MnmE helical domain SF-assemblin PF06705.11 GAP82978.1 - 0.26 10.6 25.8 1.5 8.1 9.1 2.4 1 1 1 2 2 2 0 SF-assemblin/beta giardin RB_A PF01858.17 GAP82978.1 - 0.26 11.1 9.0 5.8 6.7 1.3 3.0 2 1 1 3 3 3 0 Retinoblastoma-associated protein A domain APG6_N PF17675.1 GAP82978.1 - 0.26 11.8 6.0 0.89 10.1 5.8 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1451 PF07295.11 GAP82978.1 - 0.28 11.2 9.7 1.5 8.8 2.8 2.5 1 1 1 2 2 2 0 Zinc-ribbon containing domain Muted PF14942.6 GAP82978.1 - 0.28 11.5 15.1 0.67 10.3 5.3 2.5 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein GLE1 PF07817.13 GAP82978.1 - 0.29 10.3 17.2 2 7.6 5.0 3.0 1 1 2 3 3 3 0 GLE1-like protein DUF2130 PF09903.9 GAP82978.1 - 0.31 10.3 13.7 0.5 9.6 2.6 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) FAM184 PF15665.5 GAP82978.1 - 0.32 10.7 10.3 1.5 8.6 3.5 2.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Lectin_N PF03954.14 GAP82978.1 - 0.36 10.6 10.6 0.2 11.4 4.4 2.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF2205 PF10224.9 GAP82978.1 - 0.4 10.7 12.8 19 5.3 0.2 4.8 1 1 6 7 7 7 0 Short coiled-coil protein SOGA PF11365.8 GAP82978.1 - 0.42 11.8 3.6 1.8 9.8 1.0 2.6 1 1 1 2 2 2 0 Protein SOGA LPP PF04728.13 GAP82978.1 - 0.42 11.0 28.6 5.2 7.5 0.8 6.3 2 1 3 5 5 5 0 Lipoprotein leucine-zipper Herpes_UL92 PF03048.14 GAP82978.1 - 0.6 9.8 11.5 1.1 9.0 2.7 2.8 1 1 2 3 3 3 0 UL92 family DUF3450 PF11932.8 GAP82978.1 - 0.65 9.2 21.7 0.74 9.1 9.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) EF-G-binding_N PF07299.11 GAP82978.1 - 0.65 10.6 14.9 3.5 8.2 4.8 4.2 1 1 3 4 4 4 0 Elongation factor G-binding protein, N-terminal DUF148 PF02520.17 GAP82978.1 - 0.69 10.1 24.1 1.8 8.7 10.2 3.2 1 1 3 4 4 4 0 Domain of unknown function DUF148 DUF1515 PF07439.11 GAP82978.1 - 0.8 9.8 11.9 1.3 9.0 2.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) DHR10 PF18595.1 GAP82978.1 - 0.82 9.8 12.7 0.14 12.3 1.8 3.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain T3SS_needle_F PF09392.10 GAP82978.1 - 0.83 9.9 21.4 17 5.7 0.5 5.9 1 1 3 4 4 4 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF HTH_19 PF12844.7 GAP82978.1 - 0.84 9.7 3.8 5.1 7.2 0.5 3.2 1 1 2 3 3 3 0 Helix-turn-helix domain Exonuc_VII_L PF02601.15 GAP82978.1 - 0.87 9.1 15.6 11 5.5 15.6 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit SH3BP5 PF05276.14 GAP82978.1 - 0.97 9.2 14.9 2.1 8.1 1.9 3.5 1 1 3 4 4 4 0 SH3 domain-binding protein 5 (SH3BP5) KxDL PF10241.9 GAP82978.1 - 1.1 9.6 14.0 7.2 7.0 0.9 3.7 1 1 2 3 3 3 0 Uncharacterized conserved protein COG5 PF10392.9 GAP82978.1 - 1.1 9.5 13.5 11 6.3 8.9 3.3 2 1 1 3 3 2 0 Golgi transport complex subunit 5 SKA2 PF16740.5 GAP82978.1 - 1.1 9.1 13.7 1.1 9.0 3.8 3.5 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 RasGAP_C PF03836.15 GAP82978.1 - 1.1 9.4 19.1 13 5.9 10.3 3.2 1 1 1 2 2 2 0 RasGAP C-terminus DUF3235 PF11574.8 GAP82978.1 - 1.4 9.8 6.2 11 7.0 0.4 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3235) DUF948 PF06103.11 GAP82978.1 - 1.5 9.2 30.2 11 6.4 4.6 4.3 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 GAP82978.1 - 1.8 8.7 25.9 1.1 9.4 9.0 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 GAP82978.1 - 1.9 9.0 11.5 3.8 8.0 6.6 2.9 1 1 2 3 3 3 0 Spectrin repeat Gp-FAR-1 PF05823.12 GAP82978.1 - 2.9 8.2 8.1 5.8 7.3 3.3 2.5 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ABC_tran_CTD PF16326.5 GAP82978.1 - 2.9 8.2 7.5 6e+02 0.8 6.1 4.3 2 1 1 3 3 2 0 ABC transporter C-terminal domain ACCA PF03255.14 GAP82978.1 - 3 7.7 13.3 5 7.0 0.8 3.4 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit z-alpha PF02295.17 GAP82978.1 - 3 7.9 8.5 20 5.3 0.3 3.8 1 1 4 5 5 5 0 Adenosine deaminase z-alpha domain GLTP PF08718.11 GAP82978.1 - 4.9 7.4 12.6 22 5.3 0.1 3.5 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) GrpE PF01025.19 GAP82978.1 - 5.1 6.7 14.6 8.4 6.0 4.9 2.8 1 1 2 3 3 3 0 GrpE FliT PF05400.13 GAP82978.1 - 6.2 7.7 15.4 5.2 8.0 1.3 3.5 2 1 2 4 4 3 0 Flagellar protein FliT DUF2508 PF10704.9 GAP82978.1 - 6.3 7.1 15.2 11 6.2 0.4 5.1 2 1 6 8 8 6 0 Protein of unknown function (DUF2508) DUF3708 PF12501.8 GAP82978.1 - 6.5 6.5 9.5 29 4.4 0.9 3.0 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter Glycoprot_B_PH2 PF17417.2 GAP82978.1 - 7.6 6.9 7.0 6.4 7.2 1.1 2.5 1 1 1 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain Holin_BhlA PF10960.8 GAP82978.1 - 8.1 6.5 10.1 49 4.0 0.0 4.4 2 1 0 3 3 3 0 BhlA holin family DUF2203 PF09969.9 GAP82978.1 - 8.9 7.1 11.4 21 5.8 1.1 3.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Nnf1 PF03980.14 GAP82978.1 - 9.8 6.6 14.8 9.2e+02 0.3 0.1 3.6 1 1 1 2 2 1 0 Nnf1 ADH_N PF08240.12 GAP82979.1 - 1.3e-21 76.5 1.5 2.5e-21 75.6 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP82979.1 - 9.2e-13 48.3 0.0 1.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 GAP82979.1 - 0.00028 20.3 0.2 0.00047 19.6 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAP82979.1 - 0.027 13.7 0.2 0.04 13.2 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GAP82979.1 - 0.24 11.2 0.2 0.36 10.7 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 GAP82980.1 - 2.3e-10 40.2 0.0 0.008 15.7 0.0 3.3 2 1 1 3 3 3 3 short chain dehydrogenase Epimerase PF01370.21 GAP82980.1 - 0.0018 17.8 0.0 0.0038 16.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAP82980.1 - 0.0063 16.5 0.1 0.013 15.4 0.1 1.6 1 1 0 1 1 1 1 KR domain CBFD_NFYB_HMF PF00808.23 GAP82981.1 - 6.4e-11 42.4 0.1 1.2e-10 41.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAP82981.1 - 4.7e-09 36.7 2.5 4.7e-09 36.7 2.5 2.8 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 GAP82981.1 - 0.018 15.1 1.0 0.037 14.1 0.0 1.9 2 0 0 2 2 2 0 hTAFII28-like protein conserved region CENP-T_C PF15511.6 GAP82981.1 - 0.02 15.0 0.1 0.031 14.4 0.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold HLH PF00010.26 GAP82982.1 - 1.5e-12 47.2 0.8 3.3e-12 46.2 0.2 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 GAP82982.1 - 0.00071 19.7 6.9 0.00071 19.7 6.9 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit MHYT PF03707.16 GAP82983.1 - 0.066 13.4 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DFRP_C PF16543.5 GAP82983.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 RCR PF12273.8 GAP82983.1 - 3.1 8.5 6.2 16 6.2 6.2 2.2 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Pkinase PF00069.25 GAP82984.1 - 3e-68 230.0 0.0 6.6e-68 228.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP82984.1 - 3e-36 125.0 0.0 5.8e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP82984.1 - 0.00049 19.5 0.0 0.0015 17.9 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 GAP82984.1 - 0.034 13.2 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 GAP82984.1 - 0.047 13.6 0.1 0.29 11.0 0.1 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family SLD3 PF08639.10 GAP82985.1 - 1.3e-160 535.7 6.7 1.3e-160 535.7 6.7 1.6 2 0 0 2 2 2 1 DNA replication regulator SLD3 RNB PF00773.19 GAP82986.1 - 5.6e-98 328.3 0.0 8.5e-98 327.7 0.0 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 GAP82986.1 - 1.3e-30 105.2 0.0 3.9e-30 103.6 0.0 1.9 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 GAP82986.1 - 1.9e-28 99.0 0.0 4.2e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 GAP82986.1 - 4.5e-20 71.4 0.0 1.2e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 GAP82986.1 - 9.1e-11 42.2 0.1 5e-10 39.8 0.1 2.3 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 GAP82986.1 - 9.4e-08 32.1 3.0 0.0004 20.5 0.0 3.2 4 0 0 4 4 4 2 Cold shock domain Dis3l2_C_term PF17877.1 GAP82986.1 - 0.016 15.5 0.1 0.14 12.5 0.0 2.4 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal DUF2748 PF10871.8 GAP82987.1 - 0.21 10.1 0.1 0.27 9.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) CRC_subunit PF08624.10 GAP82988.1 - 4.8e-52 176.0 0.0 6.9e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit GN3L_Grn1 PF08701.11 GAP82989.1 - 1.5e-26 92.3 18.9 2.6e-26 91.5 18.9 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 GAP82989.1 - 4.1e-16 59.1 0.0 1.7e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP82989.1 - 7e-09 35.8 0.1 3.6e-08 33.5 0.1 1.9 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 GAP82989.1 - 2.2e-05 24.1 0.0 0.12 11.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 GAP82989.1 - 0.0004 20.5 9.7 0.25 11.4 0.0 3.9 3 1 0 4 4 4 2 Dynamin family FeoB_N PF02421.18 GAP82989.1 - 0.00062 19.3 0.1 0.016 14.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 GAP82989.1 - 0.028 13.4 0.1 0.028 13.4 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 GAP82989.1 - 0.04 13.4 0.0 0.43 10.0 0.0 2.2 1 1 1 2 2 2 0 ADP-ribosylation factor family IIGP PF05049.13 GAP82989.1 - 0.049 12.7 1.0 0.05 12.6 0.1 1.4 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) cobW PF02492.19 GAP82989.1 - 0.11 12.0 0.2 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Nuc_deoxyri_tr2 PF15891.5 GAP82989.1 - 0.18 12.1 1.7 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like TFIIA PF03153.13 GAP82989.1 - 0.6 10.1 16.4 0.99 9.3 16.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_16 PF13191.6 GAP82989.1 - 0.68 10.3 0.0 0.68 10.3 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain Ank_2 PF12796.7 GAP82990.1 - 1.4e-28 99.3 0.0 5.3e-10 39.8 0.0 4.6 3 1 2 5 5 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP82990.1 - 1.9e-25 88.5 13.2 1.1e-09 38.3 0.6 5.5 2 1 5 7 7 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP82990.1 - 1.6e-21 74.1 1.1 0.00061 20.1 0.0 7.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 GAP82990.1 - 2.3e-21 75.9 4.3 2.5e-08 34.3 0.1 6.4 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 GAP82990.1 - 1.4e-18 66.4 4.4 2.1e-07 31.1 0.1 6.3 6 0 0 6 6 6 4 Ankyrin repeat NACHT PF05729.12 GAP82990.1 - 3.1e-07 30.5 0.0 6.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP82990.1 - 1.9e-06 28.4 0.5 6.8e-06 26.6 0.2 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP82990.1 - 4.1e-06 27.1 0.0 1.3e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 GAP82990.1 - 0.0028 16.9 1.0 0.015 14.6 0.1 2.1 1 1 1 2 2 2 1 KAP family P-loop domain AAA PF00004.29 GAP82990.1 - 0.0067 16.8 0.0 0.025 15.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAP82990.1 - 0.027 14.8 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 GAP82990.1 - 0.058 12.6 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 GAP82990.1 - 0.14 12.7 0.0 0.42 11.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter HECT PF00632.25 GAP82990.1 - 0.15 11.5 0.1 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) AAA_30 PF13604.6 GAP82990.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain PNP_UDP_1 PF01048.20 GAP82991.1 - 0.024 13.9 0.0 0.096 11.9 0.0 2.0 2 0 0 2 2 2 0 Phosphorylase superfamily Ank_2 PF12796.7 GAP82993.1 - 1.5e-30 105.6 0.7 1.1e-08 35.6 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP82993.1 - 5.6e-20 71.4 5.7 5.8e-08 33.1 0.0 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP82993.1 - 1.6e-19 67.9 7.3 0.0006 20.1 0.0 8.4 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 GAP82993.1 - 1.1e-17 63.5 13.1 1.6e-06 28.3 0.1 7.7 6 2 1 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 GAP82993.1 - 4.6e-16 58.7 11.7 7.5e-05 22.9 0.0 6.4 4 1 3 7 7 7 4 Ankyrin repeats (many copies) HET PF06985.11 GAP82993.1 - 2.4e-11 44.2 9.3 3.5e-10 40.4 3.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_14 PF01373.17 GAP82998.1 - 0.0093 14.9 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Granulin PF00396.18 GAP82999.1 - 0.063 13.6 5.5 0.4 11.1 1.4 2.3 2 0 0 2 2 2 0 Granulin HAD_2 PF13419.6 GAP83000.1 - 7.9e-21 74.9 0.0 1e-20 74.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP83000.1 - 1e-09 39.0 0.0 1.7e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAP83000.1 - 2.4e-07 31.3 0.0 3.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP83000.1 - 0.002 18.2 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 GAP83000.1 - 0.016 15.3 0.0 0.24 11.5 0.0 2.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribosomal_S21 PF01165.20 GAP83001.1 - 0.02 14.6 0.0 1.1 9.0 0.0 2.5 2 1 0 2 2 2 0 Ribosomal protein S21 mono-CXXC PF15626.6 GAP83002.1 - 0.13 12.6 0.2 0.36 11.2 0.0 1.7 1 1 1 2 2 2 0 single CXXC unit Homeodomain PF00046.29 GAP83003.1 - 2.1e-16 59.5 0.5 4.5e-16 58.4 0.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAP83003.1 - 0.00014 21.7 0.2 0.00034 20.5 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain CENP-B_dimeris PF09026.10 GAP83003.1 - 0.24 11.8 13.6 0.55 10.7 13.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIA PF03153.13 GAP83003.1 - 3.8 7.4 15.1 0.29 11.1 8.9 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PNISR PF15996.5 GAP83003.1 - 6.3 7.0 14.4 12 6.1 14.4 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Fungal_trans PF04082.18 GAP83004.1 - 5.2e-13 48.6 0.0 9.4e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP83004.1 - 2.8e-06 27.3 13.9 4.3e-06 26.7 13.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP83005.1 - 1.3e-14 53.9 1.8 1.9e-14 53.4 1.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP83005.1 - 2e-07 31.0 9.3 3.2e-07 30.3 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 GAP83006.1 - 6.9e-98 328.4 21.5 7.9e-98 328.2 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP83006.1 - 6.6e-30 104.2 35.1 5.1e-24 84.9 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5134 PF17197.4 GAP83006.1 - 0.11 12.3 1.7 0.27 11.1 1.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) M20_dimer PF07687.14 GAP83007.1 - 8.7e-06 25.6 0.1 2.1e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 GAP83007.1 - 2.3e-05 24.2 2.3 8.1e-05 22.4 2.3 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Arginosuc_synth PF00764.19 GAP83008.1 - 1.7e-08 34.2 0.0 1.2e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Arginosuccinate synthase TPR_9 PF13371.6 GAP83009.1 - 8.2e-06 25.9 0.1 3.5e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Glyco_hydro_7 PF00840.20 GAP83010.1 - 5.3e-198 658.1 17.5 6e-198 657.9 17.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CorA PF01544.18 GAP83012.1 - 7.4e-09 35.3 4.5 1e-07 31.6 2.7 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Zot PF05707.12 GAP83012.1 - 0.031 13.9 0.0 0.13 11.9 0.0 2.1 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DHDPS PF00701.22 GAP83013.1 - 1.2e-19 70.2 0.0 1.5e-18 66.5 0.0 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family SUKH-4 PF14435.6 GAP83013.1 - 0.015 15.4 1.4 0.17 11.9 0.3 2.3 1 1 1 2 2 2 0 SUKH-4 immunity protein Glyco_hydro_17 PF00332.18 GAP83014.1 - 9.4e-06 25.4 1.0 2.7e-05 23.9 1.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF5127 PF17168.4 GAP83014.1 - 0.085 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5127) 2OG-FeII_Oxy_3 PF13640.6 GAP83015.1 - 1.2e-10 42.1 0.0 2.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 GAP83016.1 - 1.1e-08 35.0 7.5 1.4e-08 34.6 7.5 1.2 1 0 0 1 1 1 1 MYND finger Glyco_hydro_28 PF00295.17 GAP83017.1 - 1.6e-46 158.9 4.3 2e-46 158.6 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_76 PF03663.14 GAP83018.1 - 5e-124 414.5 17.3 1.7e-108 363.4 15.4 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 GAP83018.1 - 0.037 13.1 7.7 0.61 9.1 0.2 3.1 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Herpes_LMP2 PF07415.11 GAP83019.1 - 0.1 11.3 0.2 0.15 10.8 0.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Sds3 PF08598.11 GAP83020.1 - 0.094 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Sds3-like RRM_1 PF00076.22 GAP83021.1 - 2.4e-17 62.5 4.2 8.7e-11 41.5 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAP83021.1 - 0.00028 21.0 0.1 0.036 14.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 GAP83021.1 - 0.056 13.5 2.4 0.07 13.2 0.8 2.0 2 0 0 2 2 2 0 RNA binding motif PRELI PF04707.14 GAP83023.1 - 1.5e-42 145.1 1.3 1.8e-42 144.9 1.3 1.1 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.14 GAP83023.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain NACHT_N PF17100.5 GAP83024.1 - 3e-62 210.4 0.1 9.1e-62 208.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Ank PF00023.30 GAP83024.1 - 1.7e-50 167.3 8.2 3.7e-09 36.6 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 GAP83024.1 - 3.5e-49 164.6 7.3 2.7e-11 43.8 0.1 6.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP83024.1 - 1.5e-43 147.3 18.2 2.5e-18 66.4 0.4 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP83024.1 - 3.7e-34 116.3 0.8 1.1e-10 41.5 0.0 5.1 3 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP83024.1 - 6.3e-31 103.0 3.3 0.00021 21.5 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat AAA_16 PF13191.6 GAP83024.1 - 6.6e-06 26.6 0.0 3.1e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 GAP83024.1 - 1.1e-05 25.4 0.2 3.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 GAP83024.1 - 0.015 15.6 0.0 0.055 13.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 GAP83024.1 - 0.033 13.4 0.0 0.17 11.1 0.0 2.1 1 1 0 2 2 2 0 KAP family P-loop domain YcgL PF05166.13 GAP83024.1 - 0.049 14.0 1.4 12 6.3 0.0 4.0 2 1 2 4 4 4 0 YcgL domain Sigma54_activ_2 PF14532.6 GAP83024.1 - 0.096 12.8 0.0 6.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 GAP83024.1 - 0.11 12.9 0.0 0.85 10.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PepSY_2 PF13670.6 GAP83025.1 - 0.21 11.6 1.6 0.51 10.4 1.6 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Pyr_redox_3 PF13738.6 GAP83029.1 - 8.4e-18 64.7 0.0 2.8e-15 56.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP83029.1 - 7.9e-14 51.6 0.0 2.3e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP83029.1 - 3.9e-08 32.8 0.1 1.4e-05 24.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 GAP83029.1 - 4.5e-08 32.0 0.0 2.6e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAP83029.1 - 2.3e-06 27.7 0.0 1.3e-05 25.3 0.0 2.4 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAP83029.1 - 1.1e-05 24.9 0.0 6.8e-05 22.3 0.1 2.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 GAP83029.1 - 3.8e-05 24.1 0.1 0.36 11.4 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP83029.1 - 6.3e-05 22.2 0.5 0.00017 20.8 0.8 1.5 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 GAP83029.1 - 0.00021 20.5 1.0 0.004 16.3 0.5 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 GAP83029.1 - 0.00035 19.4 0.2 0.0011 17.7 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.20 GAP83029.1 - 0.00035 20.6 0.1 0.4 10.7 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase SnoaL_2 PF12680.7 GAP83029.1 - 0.0004 21.0 0.0 0.0012 19.4 0.0 1.9 1 0 0 1 1 1 1 SnoaL-like domain AlaDh_PNT_C PF01262.21 GAP83029.1 - 0.0011 18.3 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAP83029.1 - 0.0023 17.2 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 GAP83029.1 - 0.0058 16.0 0.1 0.042 13.2 0.1 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 GAP83029.1 - 0.0071 16.8 0.0 3.8 8.0 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.7 GAP83029.1 - 0.0072 15.7 0.3 0.013 14.9 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 GAP83029.1 - 0.017 15.4 0.1 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain SnoaL_4 PF13577.6 GAP83029.1 - 0.054 13.6 0.2 0.4 10.8 0.2 2.3 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 GAP83029.1 - 0.11 12.9 0.3 0.26 11.7 0.0 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4440) DAO PF01266.24 GAP83029.1 - 0.13 11.8 0.6 0.66 9.5 0.3 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAP83029.1 - 0.21 10.6 0.1 0.33 10.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Gpr1_Fun34_YaaH PF01184.19 GAP83030.1 - 2.3e-31 109.0 17.2 2.8e-31 108.8 17.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Dicty_CAR PF05462.11 GAP83030.1 - 0.14 11.3 5.7 0.19 10.8 5.7 1.1 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor ADH_zinc_N PF00107.26 GAP83032.1 - 0.00012 22.1 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3A PF00803.18 GAP83032.1 - 0.042 13.2 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 3A/RNA2 movement protein family F-box-like PF12937.7 GAP83033.1 - 0.0002 21.1 0.8 0.00055 19.8 0.8 1.7 1 0 0 1 1 1 1 F-box-like GMC_oxred_N PF00732.19 GAP83034.1 - 1.7e-30 106.4 0.0 4.6e-30 105.0 0.1 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP83034.1 - 1.1e-22 81.1 0.0 2.3e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAP83034.1 - 3.5e-05 23.2 0.3 0.0048 16.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP83034.1 - 0.0015 17.9 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MtrD PF04207.12 GAP83034.1 - 0.013 15.2 1.1 0.018 14.7 0.0 1.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D FAD_binding_2 PF00890.24 GAP83034.1 - 0.013 14.6 1.7 0.033 13.3 0.4 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 GAP83034.1 - 0.032 13.3 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAP83034.1 - 0.046 13.0 0.1 0.086 12.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 GAP83034.1 - 7.8 6.8 6.7 0.59 10.4 0.4 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HET PF06985.11 GAP83035.1 - 3.3e-21 76.2 0.0 7.7e-21 75.0 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UTP15_C PF09384.10 GAP83036.1 - 6e-47 159.0 0.0 9e-47 158.4 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 GAP83036.1 - 4.8e-17 62.0 6.6 7.1e-05 23.5 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP83036.1 - 3.1e-07 30.6 0.0 0.018 15.4 0.0 3.9 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain ECH_1 PF00378.20 GAP83037.1 - 2.2e-40 138.6 0.2 4.7e-40 137.5 0.2 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAP83037.1 - 2.8e-28 99.4 0.1 9.3e-25 87.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Tfb5 PF06331.12 GAP83038.1 - 1.5e-25 89.0 1.3 1.8e-25 88.7 1.3 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Aldo_ket_red PF00248.21 GAP83040.1 - 1.4e-67 228.0 0.0 1.6e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.6 GAP83040.1 - 0.042 14.1 0.1 0.077 13.2 0.1 1.3 1 0 0 1 1 1 0 FliG middle domain PspB PF06667.12 GAP83041.1 - 0.12 12.5 0.1 9.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Phage shock protein B Ribosomal_L16 PF00252.18 GAP83043.1 - 3.6e-44 150.0 0.1 4.5e-44 149.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.26 GAP83044.1 - 4.8e-23 80.7 0.0 5.6e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3450 PF11932.8 GAP83045.1 - 0.0026 17.1 17.6 0.041 13.2 13.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) Vac7 PF12751.7 GAP83046.1 - 7.8e-149 496.3 2.9 7.8e-149 496.3 2.9 2.5 2 1 0 2 2 2 1 Vacuolar segregation subunit 7 PRP1_N PF06424.12 GAP83047.1 - 9e-47 159.2 7.2 2.7e-29 102.5 2.7 2.9 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 GAP83047.1 - 5.6e-31 104.6 40.5 4.6e-06 27.0 0.5 13.8 4 2 12 16 16 15 11 Tetratricopeptide repeat TPR_19 PF14559.6 GAP83047.1 - 6.1e-29 100.3 17.5 2.9e-08 34.1 1.6 9.7 5 3 3 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAP83047.1 - 2.3e-13 49.2 10.0 0.3 11.3 0.0 10.0 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAP83047.1 - 6.5e-13 49.1 25.4 0.00047 20.7 0.1 8.6 5 2 2 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAP83047.1 - 3.1e-09 36.3 0.0 0.58 10.5 0.0 7.4 10 0 0 10 10 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAP83047.1 - 5.7e-09 35.7 4.4 1.5 9.3 0.0 8.4 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAP83047.1 - 2.3e-07 30.3 26.4 0.0031 16.8 8.6 6.6 2 2 5 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 GAP83047.1 - 9.6e-06 25.2 0.4 3.4 7.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 GAP83047.1 - 1.1e-05 24.5 0.1 1.1 8.1 0.0 4.6 2 1 2 4 4 4 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 GAP83047.1 - 1.7e-05 25.1 12.0 32 5.4 0.1 9.6 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAP83047.1 - 6.7e-05 22.5 4.2 0.15 11.8 0.1 4.4 4 0 0 4 4 4 2 TPR repeat TPR_9 PF13371.6 GAP83047.1 - 0.00012 22.1 16.1 0.14 12.3 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 GAP83047.1 - 0.00013 21.8 9.3 0.024 14.3 2.2 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain Suf PF05843.14 GAP83047.1 - 0.00021 21.4 0.1 2 8.3 0.1 4.5 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) ANAPC3 PF12895.7 GAP83047.1 - 0.002 18.3 0.4 14 5.9 0.0 4.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAP83047.1 - 0.003 17.8 10.0 1.7 9.0 0.0 6.0 6 1 0 6 6 5 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GAP83047.1 - 0.0085 16.0 9.4 1.8 8.5 0.5 4.6 2 1 2 4 4 4 2 Virulence factor membrane-bound polymerase, C-terminal TPR_7 PF13176.6 GAP83047.1 - 0.013 15.5 1.5 30 5.0 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4363 PF14276.6 GAP83047.1 - 4.6 7.4 5.4 1.2e+02 2.8 0.4 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) RrnaAD PF00398.20 GAP83048.1 - 5.2e-60 202.8 0.0 7.1e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 GAP83048.1 - 1.1e-07 32.5 0.0 2.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP83048.1 - 7e-07 29.8 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAP83048.1 - 0.00027 20.8 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GAP83048.1 - 0.00037 20.3 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP83048.1 - 0.00045 19.8 0.0 0.00073 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GAP83048.1 - 0.00086 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP83048.1 - 0.00095 19.9 0.0 0.0021 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAP83048.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.20 GAP83048.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_28 PF02636.17 GAP83048.1 - 0.044 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 GAP83048.1 - 0.069 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_4 PF02390.17 GAP83048.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 GAP83048.1 - 0.085 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 GAP83048.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 GAP83048.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 GAP83048.1 - 0.19 11.3 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) V-ATPase_G_2 PF16999.5 GAP83049.1 - 0.21 12.0 15.2 0.34 11.4 9.3 2.3 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 GAP83049.1 - 0.43 10.7 16.9 0.23 11.5 10.5 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) FSA_C PF10479.9 GAP83050.1 - 0.0035 15.6 2.8 0.0045 15.2 2.8 1.1 1 0 0 1 1 1 1 Fragile site-associated protein C-terminus DUF3439 PF11921.8 GAP83050.1 - 0.75 9.8 14.5 1.4 8.9 14.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAP83050.1 - 9.5 6.2 27.6 0.54 10.3 22.0 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Hamartin PF04388.12 GAP83051.1 - 2 7.0 24.4 3.4 6.2 24.4 1.3 1 0 0 1 1 1 0 Hamartin protein He_PIG PF05345.12 GAP83052.1 - 1.4e-15 57.2 7.9 0.00013 22.1 1.2 4.1 4 0 0 4 4 4 3 Putative Ig domain PP2C PF00481.21 GAP83053.1 - 3.2e-81 272.7 0.0 5e-81 272.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PPR_2 PF13041.6 GAP83054.1 - 1.7e-05 24.9 0.0 0.0058 16.8 0.1 3.3 3 0 0 3 3 3 2 PPR repeat family Peptidase_M20 PF01546.28 GAP83055.1 - 9.7e-35 120.1 0.0 2.5e-34 118.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAP83055.1 - 6.5e-13 48.6 0.0 1.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Methyltransf_16 PF10294.9 GAP83056.1 - 1e-42 145.8 0.0 1.3e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 GAP83056.1 - 0.072 12.9 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DPBB_1 PF03330.18 GAP83057.1 - 0.00019 21.6 0.0 0.0025 18.1 0.0 2.3 2 1 0 2 2 2 1 Lytic transglycolase CCDC53 PF10152.9 GAP83057.1 - 2.9 8.3 6.1 4.8 7.6 6.1 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF1712 PF08217.11 GAP83058.1 - 4.3e-14 51.9 0.0 5.9e-12 44.9 0.0 2.8 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1712) Mito_fiss_reg PF05308.11 GAP83058.1 - 0.02 15.0 6.3 0.047 13.8 6.3 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator Di19_C PF14571.6 GAP83058.1 - 0.62 10.6 0.0 0.62 10.6 0.0 2.8 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal Pep1_7 PF17232.2 GAP83058.1 - 2.5 8.6 4.8 1.2 9.6 1.3 2.2 2 0 0 2 2 2 0 Elicitor peptide 1-7 TRP PF06011.12 GAP83059.1 - 2.2e-160 534.1 27.4 2.7e-160 533.8 27.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 GAP83059.1 - 1.3e-44 151.9 1.2 2.7e-44 150.9 1.2 1.5 1 0 0 1 1 1 1 ML-like domain UPF0242 PF06785.11 GAP83059.1 - 0.077 13.1 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TcpE PF12648.7 GAP83059.1 - 1.3 9.6 11.8 2.2 8.9 1.0 3.2 2 1 0 2 2 2 0 TcpE family Glyco_hydro_35 PF01301.19 GAP83060.1 - 3.7e-79 266.6 0.0 5.4e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 GAP83060.1 - 0.0022 18.6 0.1 0.015 15.8 0.0 2.3 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Oxysterol_BP PF01237.18 GAP83061.1 - 7.6e-111 370.5 0.0 1.3e-110 369.8 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 GAP83061.1 - 4.1e-37 126.3 0.1 1.1e-36 124.9 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GAP83061.1 - 3e-07 30.9 0.0 8.1e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 PH domain PQQ PF01011.21 GAP83061.1 - 0.78 9.8 2.6 8.7 6.5 0.2 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat SH2_2 PF14633.6 GAP83062.1 - 7.7e-86 287.0 0.0 7.7e-86 287.0 0.0 2.8 3 0 0 3 3 3 1 SH2 domain HTH_44 PF14641.6 GAP83062.1 - 2.5e-38 131.0 2.4 1.8e-37 128.3 1.8 2.6 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 GAP83062.1 - 5.9e-34 117.0 0.0 1.7e-33 115.5 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 GAP83062.1 - 2e-30 105.2 0.0 5e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 GAP83062.1 - 1.1e-20 74.0 30.2 1.1e-20 74.0 30.2 5.6 5 1 1 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.24 GAP83062.1 - 2.2e-06 27.7 0.0 5.5e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 GAP83062.1 - 1.5e-05 25.8 1.2 1.5e-05 25.8 1.2 3.5 2 1 0 2 2 2 1 HHH domain HHH_3 PF12836.7 GAP83062.1 - 0.001 19.3 0.0 0.0027 17.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 GAP83062.1 - 0.0042 17.4 0.2 0.011 16.1 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain B12-binding PF02310.19 GAP83062.1 - 0.026 14.6 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Pkinase PF00069.25 GAP83063.1 - 5.5e-64 216.1 0.0 6.9e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP83063.1 - 4.7e-38 131.0 0.0 6.5e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP83063.1 - 0.0012 17.7 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAP83063.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAP83063.1 - 0.026 13.5 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Hydrolase_like PF13242.6 GAP83064.1 - 6.7e-05 22.9 0.6 0.00011 22.1 0.6 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 GAP83064.1 - 8e-05 22.8 0.2 0.022 14.8 0.2 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP83064.1 - 0.00012 22.5 3.1 0.08 13.2 0.3 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAP83064.1 - 0.0013 19.1 0.4 0.26 11.7 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GAP83064.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Filament PF00038.21 GAP83065.1 - 3.6e-06 26.8 15.1 3.6e-06 26.8 15.1 4.5 3 1 2 5 5 5 2 Intermediate filament protein MCC-bdg_PDZ PF10506.9 GAP83065.1 - 0.059 13.4 0.2 0.059 13.4 0.2 4.3 4 2 1 5 5 5 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4988 PF16378.5 GAP83065.1 - 0.7 9.5 3.9 3.1 7.4 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function TSC22 PF01166.18 GAP83065.1 - 0.76 10.1 0.0 0.76 10.1 0.0 5.5 8 0 0 8 8 8 0 TSC-22/dip/bun family HALZ PF02183.18 GAP83065.1 - 8.2 6.7 19.2 10 6.5 0.1 5.6 3 1 2 5 5 5 0 Homeobox associated leucine zipper p450 PF00067.22 GAP83066.1 - 8.7e-41 140.1 0.0 2.8e-27 95.6 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 DUF3956 PF13104.6 GAP83066.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Ank_2 PF12796.7 GAP83069.1 - 2.8e-69 229.7 14.7 2.3e-11 44.1 0.1 9.7 5 4 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP83069.1 - 8.9e-48 160.1 13.8 1.7e-07 31.7 0.1 13.2 9 3 4 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP83069.1 - 9.9e-32 105.4 22.6 0.028 14.9 0.1 17.3 19 0 0 19 19 19 5 Ankyrin repeat Ank PF00023.30 GAP83069.1 - 1.4e-31 107.5 27.4 0.0046 17.3 0.1 15.3 14 1 1 15 15 15 8 Ankyrin repeat Ank_5 PF13857.6 GAP83069.1 - 2.4e-26 91.4 23.2 1.7e-05 25.0 0.2 11.9 10 3 3 13 13 13 8 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.7 GAP83069.1 - 3.7e-05 24.4 0.3 0.00041 21.0 0.0 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP83069.1 - 0.0018 17.6 0.0 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 GAP83069.1 - 0.019 14.5 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Cutinase PF01083.22 GAP83069.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Cutinase RR_TM4-6 PF06459.12 GAP83069.1 - 2.2 8.0 39.1 1.1 9.1 26.2 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SNARE_assoc PF09335.11 GAP83071.1 - 0.079 13.4 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein Ank_2 PF12796.7 GAP83072.1 - 1.5e-55 185.7 19.7 7.3e-14 52.1 0.0 9.9 4 3 7 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP83072.1 - 1.1e-33 115.2 14.5 4.6e-09 36.6 0.0 12.2 9 3 4 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP83072.1 - 1.4e-29 98.8 15.3 0.002 18.5 0.0 15.6 18 1 1 19 19 19 5 Ankyrin repeat Ank PF00023.30 GAP83072.1 - 9.6e-18 63.8 22.9 0.01 16.3 0.3 12.5 13 1 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 GAP83072.1 - 1.4e-17 63.5 16.0 0.015 15.6 0.1 11.0 9 2 3 12 12 12 3 Ankyrin repeats (many copies) p450 PF00067.22 GAP83073.1 - 9.3e-47 159.8 0.0 1.3e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nepo_coat_C PF03688.14 GAP83074.1 - 0.024 14.5 0.1 0.038 13.8 0.1 1.3 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain Hce2 PF14856.6 GAP83075.1 - 7.2e-14 51.9 0.2 9.4e-14 51.6 0.2 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor CMV_US PF08001.11 GAP83075.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 CMV US zf-C2H2 PF00096.26 GAP83077.1 - 1.2e-06 28.6 9.0 0.014 15.8 0.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP83077.1 - 0.0015 19.2 4.7 3.8 8.6 0.1 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 GAP83077.1 - 0.002 18.3 0.3 0.014 15.6 0.0 2.0 1 1 1 2 2 2 1 Aberrant zinc-finger ZapB PF06005.12 GAP83077.1 - 0.025 15.0 8.2 0.053 14.0 8.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Yuri_gagarin PF15934.5 GAP83077.1 - 0.025 14.4 0.4 0.041 13.7 0.4 1.2 1 0 0 1 1 1 0 Yuri gagarin SHE3 PF17078.5 GAP83077.1 - 0.24 11.1 2.6 0.37 10.5 2.6 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 zf-H2C2_2 PF13465.6 GAP83077.1 - 0.33 11.5 0.2 0.33 11.5 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain FOXP-CC PF16159.5 GAP83077.1 - 1.1 10.0 12.2 16 6.2 1.6 4.0 3 1 1 4 4 4 0 FOXP coiled-coil domain Glyco_hydro_127 PF07944.12 GAP83078.1 - 5.6e-98 328.7 0.0 7.9e-98 328.2 0.0 1.2 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 GAP83078.1 - 0.018 14.1 0.2 0.28 10.2 0.0 2.2 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 DUF1834 PF08873.11 GAP83078.1 - 0.021 14.5 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) Malt_amylase_C PF16657.5 GAP83078.1 - 0.054 13.6 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain BCS1_N PF08740.11 GAP83079.1 - 4.9e-36 124.5 0.1 8.1e-36 123.8 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 GAP83079.1 - 9.4e-23 81.1 0.0 1.7e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAP83079.1 - 9.2e-05 22.2 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAP83079.1 - 0.012 16.2 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAP83079.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 GAP83079.1 - 0.018 15.0 0.0 0.045 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAP83079.1 - 0.037 13.2 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 GAP83079.1 - 0.049 13.8 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAP83079.1 - 0.063 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 GAP83079.1 - 0.075 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 GAP83079.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Pyr_redox_3 PF13738.6 GAP83080.1 - 1.2e-17 64.1 0.0 1.9e-16 60.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAP83080.1 - 3.6e-17 62.0 0.0 2e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAP83080.1 - 2e-09 37.1 0.0 1e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP83080.1 - 3.4e-07 29.7 0.0 1.6e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 GAP83080.1 - 3.1e-05 23.3 0.1 0.00071 18.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 GAP83080.1 - 0.00015 21.8 0.0 0.028 14.4 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAP83080.1 - 0.0011 19.2 0.0 0.0034 17.6 0.0 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP83080.1 - 0.002 17.8 0.3 0.42 10.1 0.1 2.8 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAP83080.1 - 0.0033 17.9 0.6 8.7 7.0 0.2 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP83080.1 - 0.0041 15.9 0.0 0.57 8.8 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 GAP83080.1 - 0.077 12.1 0.0 6.2 5.8 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAP83080.1 - 0.12 11.6 0.0 0.82 8.9 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain XK-related PF09815.9 GAP83081.1 - 0.79 8.7 6.4 0.36 9.9 3.5 1.8 2 0 0 2 2 2 0 XK-related protein DUF2834 PF11196.8 GAP83081.1 - 0.79 10.1 11.6 0.58 10.5 0.7 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF2834) PS-DH PF14765.6 GAP83082.1 - 1.9e-62 211.2 0.1 3.1e-62 210.5 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 GAP83082.1 - 1e-60 205.4 0.0 3.1e-60 203.9 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP83082.1 - 8.4e-58 195.2 2.5 1.3e-57 194.6 0.7 2.3 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 GAP83082.1 - 1.1e-51 176.2 0.0 2e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP83082.1 - 1e-31 109.4 0.0 3.3e-31 107.8 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAP83082.1 - 1.3e-16 61.0 0.0 3.5e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAP83082.1 - 3.2e-08 33.3 1.0 3.7e-07 29.8 0.4 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP83082.1 - 4.2e-06 26.5 2.2 1.3e-05 24.9 0.7 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 GAP83082.1 - 3.2e-05 23.4 0.1 7.8e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 GAP83082.1 - 0.023 15.1 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site ACP_syn_III PF08545.10 GAP83082.1 - 0.031 14.1 0.3 0.095 12.6 0.3 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Transferase PF02458.15 GAP83083.1 - 1.3e-09 37.3 0.0 1.5e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Transferase family HET PF06985.11 GAP83086.1 - 6.5e-22 78.5 0.0 1.4e-21 77.3 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_6 PF01341.17 GAP83087.1 - 3.9e-99 332.2 1.2 5e-99 331.9 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 OST3_OST6 PF04756.13 GAP83088.1 - 5.3e-102 341.1 0.0 6.6e-102 340.8 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 GAP83088.1 - 0.013 16.3 2.5 0.023 15.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif HisKA_7TM PF16927.5 GAP83088.1 - 0.097 12.7 6.7 0.2 11.7 6.7 1.6 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase Phage_holin_5_2 PF16079.5 GAP83088.1 - 0.14 12.5 6.7 0.35 11.2 1.2 2.7 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V CPBP PF02517.16 GAP83088.1 - 6.6 7.2 8.0 29 5.1 8.0 2.0 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease FtsJ PF01728.19 GAP83091.1 - 7.7e-58 195.5 0.0 9.5e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 GAP83091.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP83091.1 - 0.022 14.5 0.0 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.16 GAP83092.1 - 3.1e-29 102.0 47.4 2.3e-28 99.1 47.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP83092.1 - 6.2e-09 34.8 2.0 6.2e-09 34.8 2.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SRCR_2 PF15494.6 GAP83092.1 - 0.0045 17.5 0.6 0.01 16.3 0.6 1.6 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Acyl-CoA_dh_1 PF00441.24 GAP83093.1 - 1.1e-34 119.8 0.3 1.8e-34 119.1 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 GAP83093.1 - 2.2e-21 75.7 0.1 5.2e-21 74.6 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 GAP83093.1 - 1.5e-17 63.6 0.2 3e-17 62.6 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAP83093.1 - 4.5e-06 27.0 0.0 1.2e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAP83093.1 - 1.4e-05 25.7 0.3 5.1e-05 23.9 0.0 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Amino_oxidase PF01593.24 GAP83094.1 - 1.3e-47 163.2 0.0 3.7e-47 161.6 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAP83094.1 - 3.2e-15 56.1 0.1 6.5e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP83094.1 - 4.5e-07 29.4 0.4 7.7e-05 22.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP83094.1 - 8.4e-05 23.1 2.6 0.0014 19.1 0.4 3.2 3 1 1 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP83094.1 - 0.00014 20.7 0.1 0.011 14.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 GAP83094.1 - 0.00061 19.1 0.5 0.0011 18.3 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 GAP83094.1 - 0.00063 19.8 0.6 0.24 11.3 0.2 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 GAP83094.1 - 0.0013 18.4 0.2 0.0059 16.2 0.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP83094.1 - 0.0018 17.4 0.5 0.004 16.3 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 GAP83094.1 - 0.0043 16.9 0.4 0.01 15.7 0.4 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 GAP83094.1 - 0.0065 15.9 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAP83094.1 - 0.017 14.5 0.2 0.028 13.7 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAP83094.1 - 0.04 13.0 0.4 0.078 12.0 0.4 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 GAP83094.1 - 0.088 12.0 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family ATG2_CAD PF13329.6 GAP83095.1 - 2.4e-51 173.5 0.1 7.5e-51 171.9 0.1 1.9 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 GAP83095.1 - 4.5e-32 110.3 0.2 3.6e-31 107.4 0.1 2.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 GAP83095.1 - 0.022 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Pex24p PF06398.11 GAP83096.1 - 3.6e-85 286.2 0.0 4.6e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 GAP83096.1 - 0.0017 16.8 2.0 0.003 16.0 0.7 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3292) CitMHS PF03600.16 GAP83096.1 - 0.043 13.0 0.4 0.062 12.5 0.4 1.1 1 0 0 1 1 1 0 Citrate transporter ECR1_N PF14382.6 GAP83097.1 - 1e-14 54.1 0.3 2.3e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 GAP83097.1 - 0.00012 22.3 0.1 0.00025 21.3 0.1 1.5 1 0 0 1 1 1 1 KH domain Aldedh PF00171.22 GAP83098.1 - 1.5e-74 251.2 0.0 1.7e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_L22e PF01776.17 GAP83099.1 - 4e-45 152.7 1.3 4.8e-45 152.4 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family HK97-gp10_like PF04883.12 GAP83099.1 - 0.073 14.0 0.0 0.15 13.0 0.0 1.6 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Mito_carr PF00153.27 GAP83100.1 - 1.2e-40 137.3 2.2 1.4e-17 63.4 0.0 4.0 3 1 1 4 4 4 3 Mitochondrial carrier protein SnoaL PF07366.12 GAP83101.1 - 0.076 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase PI-PLC-X PF00388.19 GAP83101.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Pkinase PF00069.25 GAP83103.1 - 5.8e-51 173.4 0.0 7.8e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP83103.1 - 2.8e-39 135.0 0.0 4e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP83103.1 - 0.0004 19.3 0.2 0.0009 18.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 GAP83103.1 - 0.0014 17.7 0.0 0.18 10.7 0.0 2.3 2 0 0 2 2 2 2 Haspin like kinase domain Kdo PF06293.14 GAP83103.1 - 0.12 11.7 0.0 0.34 10.2 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAP83103.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CorA PF01544.18 GAP83104.1 - 1.6e-09 37.5 0.0 2.5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3054 PF11255.8 GAP83104.1 - 0.042 14.4 1.0 0.083 13.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) PIG-F PF06699.11 GAP83105.1 - 3.1e-64 216.4 2.3 3.7e-64 216.2 2.3 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF4345 PF14248.6 GAP83105.1 - 1.9 8.4 12.4 0.25 11.2 6.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4345) DUF2457 PF10446.9 GAP83105.1 - 6.9 5.7 5.1 7.8 5.5 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Translin PF01997.16 GAP83106.1 - 3.2e-48 164.5 0.0 3.6e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Translin family MRP-S28 PF10213.9 GAP83107.1 - 7.6e-48 162.1 0.4 6.8e-46 155.8 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal subunit protein GlutR_dimer PF00745.20 GAP83107.1 - 0.081 13.4 0.0 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Glyco_tran_28_C PF04101.16 GAP83108.1 - 3e-12 46.8 0.0 1.6e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain F-box-like PF12937.7 GAP83109.1 - 0.063 13.2 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 F-box-like zf-B_box PF00643.24 GAP83109.1 - 0.21 11.7 6.9 2.2 8.5 1.2 2.6 2 0 0 2 2 2 0 B-box zinc finger FYVE_2 PF02318.16 GAP83109.1 - 9.3 6.5 8.4 7.2 6.9 2.4 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger MRP-L20 PF12824.7 GAP83110.1 - 8.9e-29 100.8 7.8 1e-28 100.5 7.1 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Gemini_C4 PF01492.17 GAP83112.1 - 0.2 11.6 0.3 0.2 11.6 0.3 2.8 3 0 0 3 3 3 0 Geminivirus C4 protein RasGAP PF00616.19 GAP83113.1 - 1.5e-29 103.2 0.1 1.3e-21 77.3 0.0 2.8 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 GAP83113.1 - 5.2e-05 23.5 0.0 0.00014 22.1 0.0 1.8 1 1 0 1 1 1 1 C2 domain Pro_isomerase PF00160.21 GAP83114.1 - 1.6e-47 161.7 0.3 2.3e-47 161.2 0.3 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 GAP83114.1 - 1.5e-05 24.7 2.2 0.00018 21.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP83114.1 - 0.00034 20.3 0.0 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP83114.1 - 0.0031 18.1 0.0 0.021 15.4 0.0 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAP83114.1 - 0.0075 16.5 1.6 0.044 14.1 0.3 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAP83114.1 - 0.0097 16.0 0.6 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAP83114.1 - 0.038 14.7 1.3 0.038 14.7 1.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAP83114.1 - 0.057 14.3 0.6 0.057 14.3 0.6 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3176 PF11374.8 GAP83115.1 - 3.5e-30 104.3 4.2 7.7e-30 103.2 4.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) VWA_2 PF13519.6 GAP83116.1 - 8e-07 29.7 0.0 2.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 GAP83116.1 - 0.018 15.3 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF2067 PF09840.9 GAP83116.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) PNP_UDP_1 PF01048.20 GAP83117.1 - 3.3e-06 26.5 0.2 1e-05 25.0 0.2 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily Ses_B PF17046.5 GAP83117.1 - 0.0002 21.2 2.2 0.00042 20.2 2.2 1.5 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein TPR_12 PF13424.6 GAP83118.1 - 1.3e-21 76.7 15.9 1.9e-08 34.4 0.1 8.0 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_10 PF13374.6 GAP83118.1 - 2.2e-14 52.8 10.8 0.2 11.6 0.0 9.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAP83118.1 - 5.2e-12 44.9 16.6 1.2 9.4 0.2 10.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAP83118.1 - 3.1e-10 40.4 7.4 0.48 11.0 0.0 7.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAP83118.1 - 2.4e-08 33.5 12.2 4.2 7.4 0.1 9.7 10 0 0 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP83118.1 - 8.1e-07 29.2 18.9 0.54 10.5 1.5 7.5 4 2 4 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 GAP83118.1 - 5.2e-06 26.6 3.5 4.5 8.2 0.1 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAP83118.1 - 1.5e-05 24.7 9.7 0.23 11.6 0.4 6.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAP83118.1 - 0.0001 22.2 10.4 6.8 7.2 0.3 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAP83118.1 - 0.00095 19.8 14.3 52 5.0 0.0 8.3 8 2 2 10 10 9 0 Tetratricopeptide repeat TPR_MalT PF17874.1 GAP83118.1 - 0.0013 18.1 1.8 0.0013 18.1 1.8 3.6 1 1 3 4 4 4 1 MalT-like TPR region TPR_16 PF13432.6 GAP83118.1 - 0.0016 19.1 6.1 17 6.1 0.1 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 GAP83118.1 - 0.013 15.6 2.4 0.032 14.3 0.4 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 PPR PF01535.20 GAP83118.1 - 0.37 11.2 3.3 3.4 8.1 0.0 3.9 5 0 0 5 5 4 0 PPR repeat TPR_1 PF00515.28 GAP83119.1 - 1.4e-13 50.0 19.4 0.00067 19.4 0.0 10.6 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAP83119.1 - 5.2e-13 49.1 38.7 0.00088 19.5 1.6 11.5 10 4 2 12 12 12 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAP83119.1 - 2.1e-12 46.2 40.3 0.00034 20.5 0.0 12.1 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAP83119.1 - 2.1e-10 41.1 21.3 0.011 16.3 0.0 9.5 11 0 0 11 11 10 4 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP83119.1 - 2.2e-09 37.4 31.7 5.9e-05 23.2 0.6 9.0 7 3 2 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAP83119.1 - 4.8e-08 32.6 20.6 0.00036 20.5 0.0 11.0 12 1 1 13 13 13 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAP83119.1 - 9.4e-08 31.6 2.4 0.13 12.4 0.0 6.4 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAP83119.1 - 8.2e-07 29.4 8.5 2.2 8.9 0.0 8.4 8 2 1 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAP83119.1 - 1.2e-06 28.2 17.3 0.00055 19.7 0.0 8.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP83119.1 - 4.7e-06 26.9 29.7 0.18 12.5 0.3 10.2 12 1 1 13 13 11 3 Tetratricopeptide repeat TPR_4 PF07721.14 GAP83119.1 - 0.0009 19.7 6.4 2.5 9.0 0.0 7.2 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF3775 PF12616.8 GAP83119.1 - 0.011 15.7 0.9 0.8 9.8 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3775) TPR_17 PF13431.6 GAP83119.1 - 0.023 15.1 1.9 95 3.7 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 GAP83119.1 - 0.65 10.4 2.6 1.5e+02 3.0 0.1 4.7 4 0 0 4 4 4 0 PPR repeat SPO22 PF08631.10 GAP83119.1 - 3.4 7.1 10.7 5.6 6.4 0.7 3.9 4 1 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like DEAD PF00270.29 GAP83120.1 - 3.7e-33 114.8 0.1 6e-32 110.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP83120.1 - 1.2e-26 93.2 0.1 4.6e-26 91.3 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 GAP83120.1 - 0.0071 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAP83120.1 - 0.17 12.2 0.0 3 8.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain AJAP1_PANP_C PF15298.6 GAP83121.1 - 0.0077 16.5 8.2 0.0077 16.5 8.2 2.5 2 1 1 3 3 3 1 AJAP1/PANP C-terminus CFEM PF05730.11 GAP83121.1 - 0.051 13.7 4.6 0.12 12.5 4.6 1.6 1 1 0 1 1 1 0 CFEM domain DUF2462 PF09495.10 GAP83122.1 - 2.2e-17 63.5 4.9 3.4e-17 62.9 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) PPR_2 PF13041.6 GAP83123.1 - 8.4e-16 57.9 0.0 3.9e-07 30.1 0.0 4.5 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 GAP83123.1 - 1.8e-08 34.0 0.0 0.18 12.2 0.0 3.7 3 0 0 3 3 3 3 PPR repeat PPR_1 PF12854.7 GAP83123.1 - 1.3e-07 31.2 0.0 0.0053 16.4 0.0 4.3 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 GAP83123.1 - 2.5e-07 30.7 0.0 0.00097 19.2 0.0 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 GAP83123.1 - 0.0038 16.6 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP cwf18 PF08315.12 GAP83124.1 - 3.8e-45 153.9 3.6 3.8e-45 153.9 3.6 1.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor SUZ PF12752.7 GAP83126.1 - 3.5e-15 56.5 1.9 3.5e-15 56.5 1.9 3.2 3 0 0 3 3 3 1 SUZ domain R3H PF01424.22 GAP83126.1 - 2.2e-07 30.8 0.1 5.1e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 R3H domain JAB PF01398.21 GAP83127.1 - 1.5e-18 66.9 0.0 2.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GAP83127.1 - 9.8e-15 54.9 0.2 2e-14 54.0 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UTP25 PF06862.12 GAP83128.1 - 1.6e-180 601.0 0.0 1.9e-180 600.7 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 GAP83128.1 - 0.002 17.9 0.0 0.06 13.1 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AP3D1 PF06375.11 GAP83128.1 - 0.36 11.1 10.2 0.64 10.3 10.2 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Ribosomal_L17 PF01196.19 GAP83129.1 - 3.1e-32 111.3 0.3 6.2e-32 110.4 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 AIM5 PF17050.5 GAP83130.1 - 2.8e-23 82.5 0.9 2.8e-23 82.5 0.9 2.1 3 0 0 3 3 3 1 Altered inheritance of mitochondria 5 DUF1490 PF07371.12 GAP83130.1 - 0.0075 16.3 2.6 0.0075 16.3 2.6 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1490) SR-25 PF10500.9 GAP83130.1 - 0.015 15.0 4.1 0.019 14.6 4.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CENP-H PF05837.12 GAP83130.1 - 0.061 13.7 1.4 0.13 12.7 1.4 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SAT PF16073.5 GAP83131.1 - 0.047 13.4 3.0 0.32 10.7 0.4 2.5 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis ABM PF03992.16 GAP83134.1 - 0.00024 21.2 0.1 0.00034 20.7 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.16 GAP83135.1 - 1.5e-30 106.4 34.2 1.5e-30 106.4 34.2 1.9 1 1 1 3 3 3 1 Major Facilitator Superfamily LAP1C PF05609.12 GAP83136.1 - 0.071 12.2 4.0 0.11 11.6 4.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) ORMDL PF04061.14 GAP83137.1 - 1.1e-58 196.9 3.8 1.3e-58 196.7 3.8 1.0 1 0 0 1 1 1 1 ORMDL family CCDC53 PF10152.9 GAP83139.1 - 0.017 15.5 5.4 14 6.1 0.0 3.1 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex RRN3 PF05327.11 GAP83139.1 - 0.16 10.5 0.1 0.19 10.2 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Plasmodium_Vir PF05795.11 GAP83139.1 - 0.47 9.8 1.5 0.55 9.6 1.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein UCH PF00443.29 GAP83140.1 - 1.1e-45 156.2 0.0 1.9e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAP83140.1 - 4.4e-10 39.7 0.1 0.00033 20.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SAE2 PF08573.10 GAP83141.1 - 1.1e-32 113.5 0.3 1.1e-32 113.5 0.3 2.6 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus EzrA PF06160.12 GAP83141.1 - 0.081 11.1 1.0 0.13 10.4 1.0 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA BicD PF09730.9 GAP83141.1 - 0.41 9.0 6.7 0.098 11.1 2.4 1.9 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D BBP1_C PF15272.6 GAP83141.1 - 1.1 9.0 8.7 0.1 12.4 3.2 2.0 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal FapA PF03961.13 GAP83141.1 - 2.5 6.6 3.5 4.1 5.9 3.3 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 GAP83141.1 - 2.8 8.0 10.4 8.7 6.4 10.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HOOK PF05622.12 GAP83141.1 - 5.7 5.0 10.0 2.5 6.2 1.0 2.2 2 0 0 2 2 2 0 HOOK protein zf-CCHC PF00098.23 GAP83142.1 - 6.8e-52 171.3 66.8 4.2e-09 36.1 4.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 GAP83142.1 - 5.9e-10 38.7 42.5 0.091 12.5 0.8 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 GAP83142.1 - 7.9e-08 32.1 52.2 0.048 13.6 2.0 7.0 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 GAP83142.1 - 4.4e-06 26.3 41.2 0.051 13.3 1.2 7.0 5 2 2 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 GAP83142.1 - 0.004 16.9 10.4 0.025 14.4 2.4 6.9 7 0 0 7 7 7 3 Zinc knuckle zf-CCHC_6 PF15288.6 GAP83142.1 - 0.31 10.9 51.0 0.39 10.6 0.7 6.8 5 2 2 7 7 7 0 Zinc knuckle DDHD PF02862.17 GAP83143.1 - 3.8e-65 220.2 0.4 1.3e-63 215.2 0.0 2.8 3 0 0 3 3 3 1 DDHD domain LIDHydrolase PF10230.9 GAP83143.1 - 0.02 14.5 0.1 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase AAR2 PF05282.11 GAP83143.1 - 0.071 12.5 1.1 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 AAR2 protein RNA_pol_Rpb1_1 PF04997.12 GAP83144.1 - 1.4e-81 274.2 0.4 2.2e-81 273.6 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GAP83144.1 - 7.8e-77 258.3 0.1 1.2e-76 257.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAP83144.1 - 8.6e-70 234.3 0.0 3.6e-69 232.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GAP83144.1 - 8.9e-38 129.7 0.0 2.1e-37 128.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 GAP83144.1 - 2.9e-28 97.9 0.2 7.6e-28 96.6 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Mucin PF01456.17 GAP83145.1 - 0.21 11.6 18.1 0.038 14.0 14.1 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-C2H2 PF00096.26 GAP83146.1 - 6.9e-08 32.5 15.7 0.00028 21.2 1.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.18 GAP83146.1 - 7.6e-06 26.0 11.3 2.3e-05 24.4 11.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.8 GAP83146.1 - 0.0025 18.1 4.2 0.56 10.6 0.4 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 GAP83146.1 - 0.0028 18.0 1.8 0.0028 18.0 1.8 4.6 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 GAP83146.1 - 0.003 17.3 3.3 1.7 8.5 0.4 2.9 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 GAP83146.1 - 0.027 15.3 1.2 0.027 15.3 1.2 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger DUF4187 PF13821.6 GAP83146.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-BED PF02892.15 GAP83146.1 - 0.12 12.4 2.5 0.32 11.1 2.5 1.8 1 0 0 1 1 1 0 BED zinc finger zf-met PF12874.7 GAP83146.1 - 0.25 11.8 5.2 5.2 7.6 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DZR PF12773.7 GAP83146.1 - 9.5 6.3 14.7 0.33 11.0 0.7 2.5 2 0 0 2 2 2 0 Double zinc ribbon adh_short_C2 PF13561.6 GAP83147.1 - 1.7e-54 184.8 0.1 3.1e-54 184.0 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP83147.1 - 8.7e-49 165.6 0.2 1.1e-48 165.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP83147.1 - 4.3e-14 52.8 0.4 5.9e-14 52.4 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP83147.1 - 0.13 11.7 0.1 0.29 10.6 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 GAP83148.1 - 4.1e-06 26.8 7.8 7.9e-06 25.9 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAT PF16073.5 GAP83149.1 - 6.7e-76 255.2 0.0 6.7e-76 255.2 0.0 2.4 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 GAP83149.1 - 2.2e-75 253.5 0.0 6e-75 252.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAP83149.1 - 9.1e-39 133.8 0.1 2.5e-36 125.8 0.1 2.5 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP83149.1 - 2.5e-35 121.1 0.4 6.7e-35 119.7 0.4 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 GAP83149.1 - 3.7e-24 86.1 0.0 4.4e-23 82.6 0.0 2.6 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 GAP83149.1 - 6.2e-22 77.7 3.1 1.1e-11 44.9 0.2 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.6 GAP83149.1 - 1.7e-13 50.5 0.0 2.9e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 GAP83149.1 - 1.6e-05 24.4 0.2 0.00024 20.5 0.1 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 GAP83149.1 - 0.0001 22.7 0.0 0.00033 21.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Hydrolase_4 PF12146.8 GAP83149.1 - 0.011 15.0 0.3 0.21 10.8 0.0 2.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Cu-oxidase_2 PF07731.14 GAP83150.1 - 5e-37 126.7 5.2 1.4e-34 118.7 0.2 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAP83150.1 - 2.1e-30 105.2 1.6 2.6e-29 101.7 0.5 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 GAP83150.1 - 1.7e-27 96.5 1.7 3.3e-24 85.8 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase DUF92 PF01940.16 GAP83151.1 - 1.5e-86 289.7 2.4 1.9e-86 289.3 2.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Ras PF00071.22 GAP83152.1 - 2.1e-21 76.2 0.0 3.6e-21 75.5 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAP83152.1 - 2.8e-05 24.3 0.2 0.0005 20.3 0.2 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP83152.1 - 6.9e-05 22.4 0.0 0.00065 19.2 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 GAP83152.1 - 0.00033 21.1 0.8 0.00062 20.2 0.7 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 GAP83152.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 GAP83152.1 - 0.094 13.2 0.3 0.45 11.0 0.3 2.0 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.10 GAP83152.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAP83152.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Mg_chelatase PF01078.21 GAP83152.1 - 0.11 11.8 0.2 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 GAP83152.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3433 PF11915.8 GAP83153.1 - 2.9e-37 127.0 9.1 6.3e-21 74.6 1.1 4.1 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Pho86 PF11124.8 GAP83153.1 - 0.064 12.7 0.9 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 ICL PF00463.21 GAP83154.1 - 9e-290 961.6 0.1 1e-289 961.4 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 GAP83154.1 - 1e-11 44.8 0.9 2.4e-11 43.5 0.0 2.1 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase BTB PF00651.31 GAP83155.1 - 0.021 15.0 0.0 0.084 13.1 0.0 1.9 2 1 0 2 2 2 0 BTB/POZ domain ET PF01684.16 GAP83155.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 ET module Trehalase PF01204.18 GAP83156.1 - 2.4e-191 637.0 0.1 3e-191 636.7 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 GAP83156.1 - 5.8e-17 61.1 1.4 9.4e-17 60.4 1.4 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Glyco_trans_2_3 PF13632.6 GAP83157.1 - 1.9e-49 168.3 1.0 1.9e-49 168.3 1.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAP83157.1 - 0.00047 20.0 0.0 0.0022 17.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAP83157.1 - 0.0032 17.0 0.0 0.0087 15.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 GAP83157.1 - 0.029 14.3 0.0 0.087 12.7 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase like family 2 WD40 PF00400.32 GAP83158.1 - 7.3e-25 86.8 30.9 8.3e-05 23.3 0.9 10.3 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP83158.1 - 4.6e-15 55.7 3.4 6.1e-07 29.7 0.1 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP83158.1 - 5e-06 25.7 0.0 0.019 13.9 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAP83158.1 - 0.0008 18.2 0.1 0.0021 16.8 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.12 GAP83158.1 - 0.0048 16.8 3.2 21 5.2 0.0 4.8 4 1 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 GAP83158.1 - 0.0059 16.0 0.0 0.92 8.8 0.0 2.5 1 1 1 2 2 2 2 WD40-like domain Mcl1_mid PF12341.8 GAP83158.1 - 0.031 13.6 0.1 0.069 12.5 0.1 1.6 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region HZS_alpha PF18582.1 GAP83158.1 - 0.082 13.4 0.2 13 6.3 0.0 3.7 2 2 1 3 3 3 0 Hydrazine synthase alpha subunit middle domain PQQ_3 PF13570.6 GAP83158.1 - 3.4 8.3 21.6 16 6.1 1.8 7.4 7 2 1 8 8 8 0 PQQ-like domain zf-CCHC PF00098.23 GAP83159.1 - 7.2e-60 196.6 122.4 3e-06 27.0 5.0 12.4 12 0 0 12 12 12 12 Zinc knuckle zf-CCHC_2 PF13696.6 GAP83159.1 - 1.1e-10 41.2 106.8 0.0017 18.1 3.3 12.5 12 0 0 12 12 12 9 Zinc knuckle zf-CCHC_4 PF14392.6 GAP83159.1 - 2.4e-10 40.0 78.6 0.011 15.5 0.5 12.1 11 1 1 12 12 12 9 Zinc knuckle zf-CCHC_3 PF13917.6 GAP83159.1 - 1.8e-06 27.8 94.5 0.0032 17.4 1.6 12.1 2 2 9 11 11 11 9 Zinc knuckle zf-CCHC_6 PF15288.6 GAP83159.1 - 1.4 8.8 97.6 0.34 10.8 0.5 12.2 7 3 5 12 12 12 0 Zinc knuckle Ribosomal_S28e PF01200.18 GAP83161.1 - 3.8e-31 106.9 2.1 4.2e-31 106.7 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MFS_1 PF07690.16 GAP83162.1 - 1.2e-37 129.7 30.3 1.2e-37 129.7 30.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4381 PF14316.6 GAP83162.1 - 0.0079 16.4 4.8 0.87 9.8 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4381) TMEM237 PF15383.6 GAP83162.1 - 0.2 10.7 2.4 1 8.4 0.3 2.5 2 0 0 2 2 2 0 Transmembrane protein 237 Stevor PF17410.2 GAP83162.1 - 0.35 10.4 1.1 0.56 9.7 1.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ATP-grasp_4 PF13535.6 GAP83163.1 - 2e-15 56.7 0.0 4.4e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_N PF18130.1 GAP83163.1 - 6.4e-09 36.3 0.0 1.6e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain Dala_Dala_lig_C PF07478.13 GAP83163.1 - 1.2e-06 28.2 0.0 3.7e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.19 GAP83163.1 - 7.3e-06 25.9 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 GAP83163.1 - 7.9e-05 22.8 0.1 0.051 13.6 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp domain CPSase_L_D2 PF02786.17 GAP83163.1 - 0.00026 20.6 0.0 0.001 18.6 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AMP-binding PF00501.28 GAP83164.1 - 1.5e-52 178.6 0.0 1.8e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP83164.1 - 1e-15 58.4 0.0 2.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ICE2 PF08426.10 GAP83165.1 - 1.8e-157 524.7 11.0 2e-157 524.5 11.0 1.0 1 0 0 1 1 1 1 ICE2 Fungal_trans_2 PF11951.8 GAP83166.1 - 1.2e-07 30.9 0.2 1.2e-07 30.9 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain TauD PF02668.16 GAP83167.1 - 6.5e-57 193.3 0.1 8.1e-57 193.0 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SLAC1 PF03595.17 GAP83168.1 - 1.7e-84 283.9 37.1 1.9e-84 283.7 37.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel zf-CCHC_2 PF13696.6 GAP83169.1 - 0.015 15.1 2.9 0.029 14.2 2.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Exonuc_VII_L PF02601.15 GAP83169.1 - 1.1 8.8 7.5 1.6 8.2 7.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit EIF4E-T PF10477.9 GAP83169.1 - 3.2 6.5 16.0 0.86 8.3 12.6 1.6 2 0 0 2 2 2 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Presenilin PF01080.17 GAP83169.1 - 6.4 5.4 6.4 8.5 5.0 6.4 1.1 1 0 0 1 1 1 0 Presenilin MAS20 PF02064.15 GAP83169.1 - 9.8 6.3 12.4 20 5.3 12.4 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor Ank_2 PF12796.7 GAP83170.1 - 9.1e-12 45.4 0.0 0.1 13.2 0.0 4.7 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP83170.1 - 1e-10 40.9 0.1 0.036 14.6 0.0 6.5 6 1 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 GAP83170.1 - 3.8e-10 39.7 0.8 0.047 14.1 0.3 5.6 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 GAP83170.1 - 1.1e-08 35.4 0.0 0.032 14.8 0.0 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP83170.1 - 2.9e-06 27.4 0.1 0.75 10.2 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) F-box-like PF12937.7 GAP83170.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 F-box-like TRAM_LAG1_CLN8 PF03798.16 GAP83171.1 - 1.3e-37 129.4 12.6 1.3e-37 129.4 12.6 2.1 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.11 GAP83171.1 - 1.5e-21 75.8 0.0 1.5e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein PRELI PF04707.14 GAP83172.1 - 2.1e-19 69.9 0.0 2.9e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family PalH PF08733.10 GAP83174.1 - 0.93 8.4 8.8 2.5 7.0 8.9 1.6 1 1 0 1 1 1 0 PalH/RIM21 Virul_fac_BrkB PF03631.15 GAP83174.1 - 4.4 6.8 18.0 1.1 8.8 9.8 2.3 2 0 0 2 2 2 0 Virulence factor BrkB TMIE PF16038.5 GAP83174.1 - 6.5 6.7 6.5 18 5.2 0.1 2.6 2 0 0 2 2 2 0 TMIE protein G_glu_transpept PF01019.21 GAP83176.1 - 9.6e-135 450.2 0.0 1.1e-134 450.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase LysM PF01476.20 GAP83178.1 - 4.7e-14 52.2 0.0 0.0013 18.8 0.0 4.8 4 1 1 5 5 5 4 LysM domain UPF0203 PF05254.12 GAP83178.1 - 0.00076 19.7 0.6 15 5.9 0.0 3.9 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0203) LysM PF01476.20 GAP83179.1 - 8.2e-11 41.8 0.0 5.6e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 LysM domain Ank_4 PF13637.6 GAP83180.1 - 3.6e-23 81.6 1.7 3.4e-07 30.7 0.0 7.8 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP83180.1 - 3e-20 72.6 0.2 3.3e-06 27.6 0.0 4.8 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP83180.1 - 3e-14 52.9 1.8 0.0072 16.6 0.0 6.5 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 GAP83180.1 - 3.1e-13 49.5 10.5 0.21 12.1 0.0 8.6 8 1 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 GAP83180.1 - 3.1e-12 45.5 1.8 0.017 15.6 0.0 8.4 8 1 0 8 8 8 3 Ankyrin repeat PBP1_TM PF14812.6 GAP83182.1 - 0.046 14.1 2.8 0.11 12.8 2.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3446 PF11928.8 GAP83182.1 - 9.7 6.6 9.6 2.8 8.3 3.8 2.7 3 0 0 3 3 3 0 Early growth response N-terminal domain Glyco_hydro_7 PF00840.20 GAP83183.1 - 4.7e-176 585.8 11.9 5.3e-176 585.6 11.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Beta_helix PF13229.6 GAP83185.1 - 5.9e-06 26.2 0.1 9e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 GAP83185.1 - 0.0017 17.7 0.1 0.0037 16.6 0.1 1.6 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Glutaredoxin PF00462.24 GAP83186.1 - 9.2e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF374 PF04028.13 GAP83186.1 - 0.12 11.9 0.2 0.21 11.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Flavoprotein PF02441.19 GAP83187.1 - 1.2e-41 142.1 0.0 2.6e-38 131.3 0.0 2.2 2 1 0 2 2 2 2 Flavoprotein Ribosomal_L12_N PF16320.5 GAP83187.1 - 0.0092 15.7 0.3 0.1 12.3 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain zf-CCCH_4 PF18044.1 GAP83188.1 - 1.9e-07 30.7 2.2 3.6e-07 29.8 2.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAP83188.1 - 4.4e-06 26.5 5.0 8.1e-06 25.7 5.0 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 GAP83188.1 - 3.8e-05 24.4 1.3 3.8e-05 24.4 1.3 2.8 2 0 0 2 2 2 1 Torus domain zf-CCCH PF00642.24 GAP83188.1 - 0.0001 22.1 1.5 0.00019 21.2 1.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 GAP83188.1 - 0.0092 16.2 0.1 0.0092 16.2 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 GAP83188.1 - 0.016 15.7 2.8 0.027 14.9 2.8 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger OATP PF03137.20 GAP83188.1 - 5.2 5.2 6.2 12 4.0 6.2 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sec1 PF00995.23 GAP83190.1 - 5.2e-126 422.2 0.0 6.1e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Chitin_synth_1 PF01644.17 GAP83191.1 - 4.3e-74 247.9 0.3 6.5e-74 247.3 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAP83191.1 - 4.4e-30 103.5 0.1 9.7e-30 102.4 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAP83191.1 - 3.4e-21 75.5 1.3 1.5e-15 56.8 0.0 2.5 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAP83191.1 - 1.3e-06 28.5 8.2 1.3e-06 28.5 8.2 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAP83191.1 - 0.0062 16.4 0.0 0.013 15.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 p450 PF00067.22 GAP83192.1 - 9.5e-71 238.9 0.0 1.2e-70 238.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aconitase PF00330.20 GAP83193.1 - 1.3e-144 482.6 0.0 1.7e-144 482.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAP83193.1 - 1.3e-36 125.8 0.0 2.7e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain FAD_binding_3 PF01494.19 GAP83195.1 - 2.2e-12 46.9 0.0 7.2e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP83195.1 - 2e-10 40.4 0.1 4.8e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP83195.1 - 1.4e-08 34.3 0.0 3.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP83195.1 - 2.3e-08 34.0 0.2 3.1e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP83195.1 - 9.6e-07 28.9 0.0 2.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAP83195.1 - 4.3e-06 25.7 0.0 1.7e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 GAP83195.1 - 7.9e-06 25.5 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 GAP83195.1 - 4.6e-05 22.7 0.0 7.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 GAP83195.1 - 5.2e-05 23.7 0.1 0.0003 21.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAP83195.1 - 5.9e-05 22.3 0.2 0.00037 19.7 0.2 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 GAP83195.1 - 0.00046 19.2 0.1 0.24 10.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase AlaDh_PNT_C PF01262.21 GAP83195.1 - 0.007 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 GAP83195.1 - 0.0084 15.4 0.0 0.0084 15.4 0.0 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP83195.1 - 0.031 13.5 0.6 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family MFS_1 PF07690.16 GAP83196.1 - 2.2e-34 119.0 24.1 2.2e-34 119.0 24.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sars6 PF12133.8 GAP83196.1 - 0.018 15.0 0.1 0.056 13.4 0.1 1.8 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus T_cell_tran_alt PF15128.6 GAP83196.1 - 3.1 7.7 5.8 0.53 10.1 0.1 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered YqhR PF11085.8 GAP83196.1 - 5.4 6.9 12.0 3.5 7.5 0.5 3.3 3 0 0 3 3 3 0 Conserved membrane protein YqhR Actin PF00022.19 GAP83197.1 - 3.7e-128 427.6 0.0 1.5e-127 425.6 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAP83197.1 - 0.027 13.3 0.0 6.4 5.5 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein DUF3602 PF12223.8 GAP83198.1 - 2.2e-18 66.6 11.7 1.9e-16 60.4 1.9 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Pkinase_fungal PF17667.1 GAP83200.1 - 2.4e-91 306.6 5.6 3.7e-62 210.4 0.1 3.0 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 GAP83200.1 - 4e-05 23.1 0.0 6.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAP83200.1 - 0.0066 16.4 0.2 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_C2 PF00648.21 GAP83201.1 - 1.8e-16 60.0 0.0 2.6e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease Peptidase_C1 PF00112.23 GAP83201.1 - 0.17 12.0 1.4 0.36 10.9 1.4 1.6 1 1 0 1 1 1 0 Papain family cysteine protease Acyl_transf_3 PF01757.22 GAP83202.1 - 2.5e-45 155.0 19.3 7.8e-45 153.4 19.3 1.7 1 1 0 1 1 1 1 Acyltransferase family Serglycin PF04360.12 GAP83202.1 - 0.23 11.4 5.1 0.052 13.5 1.8 1.6 2 0 0 2 2 2 0 Serglycin Peptidase_S9 PF00326.21 GAP83203.1 - 1.4e-45 155.4 0.6 2.5e-45 154.6 0.6 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 GAP83203.1 - 0.038 13.9 6.7 0.047 13.6 0.1 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Arylesterase PF01731.20 GAP83203.1 - 0.079 13.2 0.4 7.4 6.8 0.0 4.0 5 0 0 5 5 5 0 Arylesterase NHL PF01436.21 GAP83203.1 - 0.11 12.6 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 0 NHL repeat WD40 PF00400.32 GAP83204.1 - 1.5e-29 101.6 0.2 2.1e-07 31.5 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP83204.1 - 6.4e-15 55.2 0.0 0.00058 20.1 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAP83204.1 - 0.00057 19.8 0.0 0.21 11.4 0.0 3.0 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 GAP83204.1 - 0.0029 16.7 0.0 0.0094 15.0 0.0 1.7 1 1 1 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.6 GAP83204.1 - 0.0046 16.6 0.0 0.037 13.6 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 GAP83204.1 - 0.0082 15.5 0.0 0.93 8.8 0.0 2.5 1 1 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 GAP83204.1 - 0.028 13.1 0.0 0.08 11.6 0.0 1.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 SdiA-regulated PF06977.11 GAP83204.1 - 0.12 11.6 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 SdiA-regulated FTHFS PF01268.19 GAP83205.1 - 8.5e-253 839.6 0.1 1.1e-252 839.2 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 GAP83205.1 - 1.6e-68 229.0 2.5 2.3e-68 228.6 0.4 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 GAP83205.1 - 1.9e-36 124.8 0.9 4e-36 123.8 0.9 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF4588 PF15251.6 GAP83206.1 - 2.9e-07 30.5 0.0 4.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) SNF2_N PF00176.23 GAP83207.1 - 3e-74 249.8 0.0 4.9e-74 249.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 GAP83207.1 - 3.4e-42 143.1 3.6 1.7e-41 140.8 1.1 2.7 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 GAP83207.1 - 2.9e-36 124.6 3.2 2.9e-36 124.6 3.2 3.7 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 GAP83207.1 - 2.3e-18 66.6 0.0 8.4e-18 64.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP83207.1 - 5.1e-11 42.9 0.1 4.7e-10 39.7 0.0 2.8 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 GAP83207.1 - 8.3e-07 29.1 0.0 0.0089 16.2 0.0 3.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 GAP83207.1 - 6.1e-06 25.6 0.0 1.7e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF1086 PF06461.11 GAP83207.1 - 0.00071 19.4 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) DUF5618 PF18498.1 GAP83207.1 - 0.001 19.3 1.7 0.053 13.7 0.8 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5618) SWI2_SNF2 PF18766.1 GAP83207.1 - 0.0022 17.7 0.0 0.0081 15.9 0.0 2.0 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 GAP83207.1 - 0.003 17.4 0.0 0.0088 15.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 GAP83207.1 - 0.0043 16.3 0.1 0.01 15.1 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Tn7_Tnp_TnsA_C PF08721.11 GAP83207.1 - 0.058 14.0 0.1 0.31 11.7 0.1 2.3 1 0 0 1 1 1 0 TnsA endonuclease C terminal AAA_22 PF13401.6 GAP83207.1 - 0.18 12.1 0.6 1.9 8.8 0.0 3.0 4 0 0 4 4 4 0 AAA domain ALAD PF00490.21 GAP83208.1 - 5.9e-119 396.9 0.0 7.8e-119 396.5 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Avl9 PF09794.9 GAP83209.1 - 0.033 12.9 0.0 0.046 12.4 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 RIO1 PF01163.22 GAP83209.1 - 0.054 13.1 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 GAP83209.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 GAP83210.1 - 6.4e-14 51.6 54.4 6.4e-14 51.6 54.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Y_phosphatase3 PF13350.6 GAP83211.1 - 3.4e-52 177.7 0.0 3.9e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAP83211.1 - 0.00069 19.3 0.0 0.00089 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 GAP83211.1 - 0.0054 16.3 0.0 0.0075 15.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GAP83211.1 - 0.26 11.1 0.0 0.44 10.4 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Amidohydro_3 PF07969.11 GAP83212.1 - 1.3e-65 222.8 3.1 1.5e-65 222.5 3.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 GAP83212.1 - 4.6e-05 22.9 0.0 0.00076 18.9 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family PPR_3 PF13812.6 GAP83213.1 - 4.3e-07 29.9 0.0 0.02 15.0 0.0 4.8 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 GAP83213.1 - 9e-07 29.0 0.0 3.3 8.0 0.0 5.4 5 1 1 6 6 6 3 PPR repeat family PPR_long PF17177.4 GAP83213.1 - 2.3e-05 23.9 1.2 0.013 14.9 0.0 3.9 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAP83213.1 - 0.0099 16.1 3.0 5.2 7.6 0.0 5.2 6 0 0 6 6 6 1 PPR repeat Ribosomal_S18 PF01084.20 GAP83214.1 - 1.1e-10 41.5 0.0 2.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 CAP_N PF01213.19 GAP83214.1 - 6.7 6.1 8.3 9.5 5.6 8.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal S4 PF01479.25 GAP83215.1 - 9.3e-12 44.5 0.0 1.7e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 GAP83215.1 - 0.0014 19.5 0.1 0.0035 18.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain THDPS_N_2 PF14805.6 GAP83215.1 - 0.027 14.7 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal HTH_56 PF18662.1 GAP83215.1 - 0.096 12.8 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Cch helix turn helix domain HORMA PF02301.18 GAP83217.1 - 7.8e-33 113.9 0.0 9.3e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 GAP83217.1 - 0.00076 19.5 0.3 0.0043 17.1 0.1 2.2 1 1 0 2 2 2 1 Autophagy-related protein 101 DUF2660 PF10859.8 GAP83217.1 - 0.023 15.2 0.0 0.053 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF4148 PF13663.6 GAP83217.1 - 0.041 14.1 5.0 0.09 13.0 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) bacHORMA_2 PF18173.1 GAP83217.1 - 0.045 13.6 0.1 0.11 12.4 0.1 1.6 1 1 0 1 1 1 0 Bacterial HORMA domain 2 UCH PF00443.29 GAP83218.1 - 1.7e-34 119.5 0.0 2.3e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 GAP83218.1 - 3.6e-23 81.1 2.0 1.6e-22 79.0 0.2 2.4 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 GAP83218.1 - 1.3e-22 79.3 0.1 3.5e-11 42.8 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 GAP83218.1 - 4.6e-22 78.1 16.4 2.8e-18 66.0 2.5 2.9 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GAP83218.1 - 2.7e-18 66.6 1.0 8.2e-17 61.8 0.0 3.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 GAP83218.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain NifU_N PF01592.16 GAP83219.1 - 8.8e-54 181.1 0.0 1.1e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain DEAD PF00270.29 GAP83220.1 - 1.4e-50 171.4 0.0 1.1e-49 168.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP83220.1 - 1.2e-34 119.0 0.0 6.3e-32 110.2 0.0 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP83220.1 - 7.1e-07 29.4 0.0 7.1e-07 29.4 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAP83220.1 - 0.0015 17.4 0.0 0.013 14.3 0.0 2.4 3 0 0 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 GAP83220.1 - 0.0032 16.7 0.0 0.0032 16.7 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 GAP83220.1 - 0.016 14.6 0.0 0.016 14.6 0.0 4.2 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit SOBP PF15279.6 GAP83220.1 - 0.052 14.1 9.1 0.078 13.6 9.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIF_alpha PF05793.12 GAP83220.1 - 2 6.9 37.6 3.5 6.1 37.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rft-1 PF04506.13 GAP83221.1 - 1.2e-148 496.1 0.9 1.3e-148 495.9 0.9 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 GAP83221.1 - 0.0032 16.7 3.9 0.048 12.9 0.1 3.3 2 1 0 3 3 3 1 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.19 GAP83222.1 - 3.5e-53 180.9 0.0 4.7e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP83222.1 - 4.4e-37 127.8 0.0 7.2e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAP83222.1 - 7.3e-07 28.6 0.3 0.002 17.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAP83222.1 - 1.2e-05 25.1 0.5 0.00015 21.4 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAP83222.1 - 0.00014 21.3 0.7 0.24 10.6 0.2 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAP83222.1 - 0.00047 19.3 0.1 0.00078 18.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAP83222.1 - 0.0016 17.7 0.5 0.0031 16.8 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP83222.1 - 0.0083 16.3 1.4 0.018 15.2 1.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAP83222.1 - 0.01 15.1 0.2 0.13 11.5 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 GAP83222.1 - 0.065 12.1 0.3 0.1 11.5 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 GAP83222.1 - 0.082 12.9 0.2 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sugar_tr PF00083.24 GAP83223.1 - 1.2e-122 410.1 17.6 1.3e-122 409.9 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP83223.1 - 2.2e-26 92.6 28.1 1.6e-17 63.5 9.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily HgmA PF04209.13 GAP83224.1 - 9.3e-14 51.0 0.1 1.1e-13 50.8 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase RPE65 PF03055.15 GAP83225.1 - 4.2e-109 365.8 0.0 4.8e-109 365.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Lipase_GDSL PF00657.22 GAP83226.1 - 0.0001 22.4 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAP83226.1 - 0.0043 17.5 0.3 0.025 15.0 0.3 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MIT PF04212.18 GAP83227.1 - 1.7e-14 53.6 2.4 3.4e-14 52.7 2.4 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TIM PF00121.18 GAP83228.1 - 1.3e-35 122.9 0.0 3.1e-35 121.7 0.0 1.6 1 1 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 GAP83229.1 - 1.3e-40 138.6 0.3 1.5e-40 138.4 0.3 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase KptA_kDCL PF18176.1 GAP83229.1 - 0.076 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain Dak1 PF02733.17 GAP83230.1 - 3.9e-102 341.3 0.1 4.8e-102 341.0 0.1 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 GAP83230.1 - 1.3e-37 129.4 1.9 2.3e-37 128.6 1.9 1.4 1 0 0 1 1 1 1 DAK2 domain F_bP_aldolase PF01116.20 GAP83231.1 - 8.1e-84 281.4 0.4 9.1e-84 281.2 0.4 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NAD_binding_2 PF03446.15 GAP83232.1 - 1.4e-35 122.8 0.0 2.2e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAP83232.1 - 1.4e-31 109.3 0.0 1.3e-22 80.3 0.0 2.5 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAP83232.1 - 1.2e-05 25.8 0.0 6.2e-05 23.5 0.0 2.2 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 GAP83232.1 - 1.6e-05 24.8 0.7 0.0008 19.3 0.0 2.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 GAP83232.1 - 0.00052 19.7 0.0 0.00088 18.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 GAP83232.1 - 0.096 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-UBR PF02207.20 GAP83233.1 - 9.5e-14 51.3 2.7 9.5e-14 51.3 2.7 2.6 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) SCHIP-1 PF10148.9 GAP83233.1 - 0.12 12.0 0.2 0.23 11.1 0.2 1.4 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 MCM PF00493.23 GAP83234.1 - 8.7e-101 335.7 0.0 1.5e-100 334.9 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAP83234.1 - 2.5e-38 130.8 0.2 4.8e-38 129.8 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 GAP83234.1 - 7.6e-36 123.7 31.8 7.6e-36 123.7 31.8 2.2 3 0 0 3 3 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 GAP83234.1 - 1.7e-25 89.3 0.6 5.4e-25 87.6 0.6 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAP83234.1 - 8.9e-16 58.4 0.1 2.2e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAP83234.1 - 9.6e-08 31.6 0.0 6.3e-06 25.7 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAP83234.1 - 2e-06 27.8 0.0 4.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAP83234.1 - 0.00046 20.1 0.0 0.014 15.3 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAP83234.1 - 0.0021 17.8 0.2 0.015 15.0 0.2 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF3113 PF11310.8 GAP83234.1 - 0.015 15.2 0.2 2.7 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) Zn_ribbon_2 PF12674.7 GAP83234.1 - 0.054 14.2 0.4 0.16 12.6 0.4 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-TFIIB PF13453.6 GAP83234.1 - 0.097 12.0 1.9 0.21 11.0 1.9 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger AAA_16 PF13191.6 GAP83234.1 - 0.13 12.6 0.3 0.62 10.4 0.2 2.5 2 1 0 2 2 2 0 AAA ATPase domain AA_permease PF00324.21 GAP83235.1 - 1.4e-80 271.2 39.6 1.7e-80 270.9 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP83235.1 - 2.7e-31 108.9 41.3 3.2e-31 108.6 41.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4763 PF15960.5 GAP83236.1 - 0.06 12.6 0.4 0.11 11.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) TSNAXIP1_N PF15739.5 GAP83236.1 - 0.082 13.3 0.5 0.2 12.1 0.5 1.8 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Bacillus_HBL PF05791.11 GAP83236.1 - 0.12 12.2 0.3 0.21 11.4 0.3 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TolA_bind_tri PF16331.5 GAP83236.1 - 1.9 8.6 6.1 3.4 7.8 0.4 2.7 3 0 0 3 3 3 0 TolA binding protein trimerisation Rootletin PF15035.6 GAP83236.1 - 4.4 7.3 16.6 0.8 9.7 12.2 2.0 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Glyco_hydro_2_N PF02837.18 GAP83237.1 - 4.6e-15 55.9 0.1 9.2e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 GAP83237.1 - 3.8e-12 46.8 0.1 8.9e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 GAP83237.1 - 2.5e-09 36.7 0.5 7.5e-09 35.1 0.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Big_7 PF17957.1 GAP83237.1 - 0.00048 20.8 3.9 0.0093 16.7 0.1 2.9 2 0 0 2 2 2 1 Bacterial Ig domain NAD_binding_10 PF13460.6 GAP83239.1 - 1.1e-08 35.2 1.4 1.4e-08 34.9 1.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP83239.1 - 5.6e-05 22.7 0.3 7.3e-05 22.3 0.3 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAP83239.1 - 0.00059 19.5 0.3 0.00074 19.1 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 GAP83239.1 - 0.001 19.3 0.1 0.0015 18.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 GAP83239.1 - 0.0012 19.1 0.4 0.0016 18.6 0.4 1.2 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 GAP83239.1 - 0.002 17.6 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ApbA PF02558.16 GAP83239.1 - 0.0083 15.8 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 GAP83239.1 - 0.01 15.9 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 GAP83239.1 - 0.015 14.6 0.2 0.022 14.1 0.2 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAP83239.1 - 0.058 12.7 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAP83239.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_76 PF03663.14 GAP83242.1 - 8.5e-124 413.8 10.0 9.7e-124 413.6 10.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 His_Phos_1 PF00300.22 GAP83243.1 - 4.3e-18 65.7 0.0 5.3e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CTNNBL PF08216.11 GAP83244.1 - 5.3e-36 122.9 0.0 2.2e-35 121.0 0.0 2.2 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear PET117 PF15786.5 GAP83244.1 - 1.7e-25 89.0 2.9 4.3e-25 87.8 2.9 1.7 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Arm_3 PF16186.5 GAP83244.1 - 0.0015 18.0 0.1 0.58 9.8 0.1 2.9 2 0 0 2 2 2 2 Atypical Arm repeat DUF4863 PF16155.5 GAP83245.1 - 1.2e-68 229.7 0.0 1.5e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) Sugar_tr PF00083.24 GAP83246.1 - 2.8e-77 260.5 22.3 3.3e-77 260.3 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP83246.1 - 5e-13 48.7 29.8 2.5e-11 43.1 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAP83246.1 - 0.00047 19.1 4.9 0.00047 19.1 4.9 2.2 2 0 0 2 2 2 1 MFS_1 like family Fungal_trans_2 PF11951.8 GAP83247.1 - 5.8e-10 38.5 0.7 1.2e-09 37.5 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP83247.1 - 2.2e-07 30.9 9.4 4.2e-07 30.0 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIOX PF05153.15 GAP83248.1 - 8.3e-126 418.6 0.7 1.1e-125 418.3 0.7 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 GAP83248.1 - 0.023 14.9 0.0 0.67 10.2 0.0 2.3 2 0 0 2 2 2 0 HD domain NOG1_N PF17835.1 GAP83248.1 - 0.31 11.0 3.1 2.8 7.9 0.1 2.4 2 1 0 2 2 2 0 NOG1 N-terminal helical domain DUF1940 PF09155.10 GAP83248.1 - 1.3 9.1 4.8 2.4 8.3 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) DUF1996 PF09362.10 GAP83249.1 - 9.3e-86 287.6 1.1 1.2e-85 287.3 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 GAP83249.1 - 4.2e-18 65.3 3.7 4.2e-18 65.3 3.7 1.9 2 0 0 2 2 2 1 WSC domain DUF2828 PF11443.8 GAP83250.1 - 3.5e-249 828.2 0.0 4.1e-249 827.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) REV1_C PF16727.5 GAP83250.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain TFB6 PF17110.5 GAP83251.1 - 4.6e-55 186.0 7.5 2.7e-50 170.5 7.5 2.8 1 1 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH zf-CCHC PF00098.23 GAP83252.1 - 3.4e-46 153.3 59.0 5.7e-08 32.5 2.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 GAP83252.1 - 1.3e-09 37.6 40.9 0.16 11.8 1.1 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 GAP83252.1 - 5.9e-06 26.1 44.4 0.097 12.7 1.0 6.9 4 2 3 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 GAP83252.1 - 0.00016 21.3 44.0 0.018 14.7 1.0 7.1 4 2 3 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 GAP83252.1 - 0.083 12.7 0.5 0.083 12.7 0.5 7.1 6 1 1 7 7 7 0 Zinc knuckle WD40 PF00400.32 GAP83254.1 - 3.1e-38 129.1 7.4 1.1e-07 32.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP83254.1 - 2.9e-14 53.1 0.4 6.1e-05 23.2 0.0 5.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 GAP83254.1 - 3.1e-05 22.9 1.7 0.45 9.2 0.1 3.9 1 1 0 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 GAP83254.1 - 0.006 15.9 0.1 1 8.6 0.1 3.2 1 1 1 3 3 3 1 WD40-like domain DUF5046 PF16465.5 GAP83254.1 - 0.1 12.1 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) Ge1_WD40 PF16529.5 GAP83254.1 - 0.11 11.5 0.0 11 4.9 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TRAPP PF04051.16 GAP83255.1 - 1.4e-35 122.1 0.1 1.7e-35 121.9 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 GAP83255.1 - 0.058 12.2 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A LisH PF08513.11 GAP83256.1 - 0.05 13.6 0.3 0.092 12.7 0.3 1.4 1 0 0 1 1 1 0 LisH MFS_1 PF07690.16 GAP83257.1 - 2.7e-18 66.0 32.2 2.2e-12 46.6 20.2 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP83257.1 - 0.02 13.8 12.2 0.17 10.7 0.4 3.2 2 1 1 3 3 3 0 Sugar (and other) transporter MFS_1 PF07690.16 GAP83258.1 - 9.9e-26 90.5 48.5 3.1e-24 85.5 37.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAP83258.1 - 5.9e-05 22.5 20.6 8.8e-05 22.0 20.6 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 GAP83258.1 - 8.9e-05 21.1 4.7 0.00015 20.3 4.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COesterase PF00135.28 GAP83259.1 - 1.8e-77 261.3 0.0 2.3e-77 261.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP83259.1 - 1e-10 41.8 0.5 7.7e-10 39.0 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 GAP83259.1 - 0.0027 16.8 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 GAP83259.1 - 0.0033 16.4 0.0 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 GAP83259.1 - 0.093 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 GAP83259.1 - 0.18 10.6 0.1 7.3 5.3 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase PSD2 PF07624.11 GAP83260.1 - 0.057 13.2 0.2 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) CitMHS PF03600.16 GAP83260.1 - 0.4 9.8 6.4 0.41 9.8 6.4 1.1 1 0 0 1 1 1 0 Citrate transporter TAL_FSA PF00923.19 GAP83261.1 - 4.6e-24 85.2 0.0 6.4e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pkinase PF00069.25 GAP83263.1 - 5.6e-52 176.7 0.0 7.8e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP83263.1 - 2e-19 69.9 0.0 3.2e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP83263.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP83263.1 - 0.17 11.4 0.4 0.32 10.6 0.4 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mpp10 PF04006.12 GAP83264.1 - 9.6e-113 377.8 57.7 2.1e-112 376.6 57.7 1.5 1 1 0 1 1 1 1 Mpp10 protein YopX PF09643.10 GAP83264.1 - 0.57 10.3 5.9 1.8 8.6 3.4 2.8 2 1 1 3 3 3 0 YopX protein Adap_comp_sub PF00928.21 GAP83265.1 - 2.2e-68 230.5 0.0 2.7e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAP83265.1 - 0.00013 22.0 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Acyl_transf_1 PF00698.21 GAP83266.1 - 3e-23 82.8 0.2 1.8e-16 60.5 0.1 2.1 1 1 1 2 2 2 2 Acyl transferase domain DUF2458 PF10454.9 GAP83266.1 - 0.03 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Sedlin_N PF04628.13 GAP83267.1 - 2.8e-13 50.1 0.0 4.2e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAP83267.1 - 0.18 11.7 0.0 3.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Sybindin-like family Ribosomal_60s PF00428.19 GAP83267.1 - 0.23 12.1 2.0 0.5 11.0 2.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein AFG1_ATPase PF03969.16 GAP83268.1 - 1.6e-33 116.1 0.0 6.7e-17 61.4 0.0 4.1 4 0 0 4 4 4 4 AFG1-like ATPase Bac_DnaA PF00308.18 GAP83268.1 - 0.19 11.5 0.0 4 7.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein Nucleoporin_C PF03177.14 GAP83269.1 - 7e-157 523.7 12.2 7e-157 523.7 12.2 1.8 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 GAP83269.1 - 9.4e-70 235.5 0.0 1.3e-69 235.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Acetyltransf_1 PF00583.25 GAP83270.1 - 1.4e-13 51.1 0.2 2.8e-13 50.1 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP83270.1 - 2.3e-10 40.5 0.1 1.2e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP83270.1 - 1.5e-09 38.1 0.3 7e-09 36.0 0.3 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP83270.1 - 2.8e-07 30.4 0.1 6.2e-07 29.3 0.1 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 GAP83270.1 - 1.1e-05 25.5 0.1 0.01 15.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAP83270.1 - 0.015 15.4 0.1 0.032 14.4 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SUIM_assoc PF16619.5 GAP83270.1 - 0.69 10.0 11.8 1.8 8.7 11.8 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Aldolase_II PF00596.21 GAP83272.1 - 4.8e-48 163.6 0.6 7.2e-48 163.0 0.6 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TetR_N PF00440.23 GAP83272.1 - 0.26 11.1 5.5 0.52 10.1 0.0 2.8 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family Fungal_trans_2 PF11951.8 GAP83273.1 - 0.0044 15.9 0.8 0.0064 15.3 0.2 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Arrestin_N PF00339.29 GAP83275.1 - 2.7e-14 53.5 0.0 4.7e-09 36.5 0.0 3.7 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Iso_dh PF00180.20 GAP83276.1 - 1.6e-72 244.6 0.0 1.8e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ATG_C PF09333.11 GAP83276.1 - 0.15 12.4 0.5 1.1 9.6 0.2 2.2 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain AhpC-TSA PF00578.21 GAP83277.1 - 2.4e-23 82.4 0.0 3.7e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAP83277.1 - 3.4e-13 49.5 0.1 4.4e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 GAP83277.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme zf-C3HC4_4 PF15227.6 GAP83278.1 - 0.039 14.1 1.1 0.16 12.2 1.1 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2H2 PF00096.26 GAP83278.1 - 0.049 14.1 1.9 0.049 14.1 1.9 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type OrsD PF12013.8 GAP83278.1 - 3.3 8.2 12.3 0.68 10.4 0.7 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Glyco_hydro_127 PF07944.12 GAP83281.1 - 4.9e-109 365.2 0.1 6.1e-109 364.9 0.1 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Not3 PF04065.15 GAP83282.1 - 5.1e-91 304.2 19.5 5.1e-91 304.2 19.5 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 GAP83282.1 - 3.6e-41 140.3 11.5 9e-41 139.0 11.5 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 GAP83282.1 - 0.0048 17.2 1.9 0.0048 17.2 1.9 3.0 5 0 0 5 5 5 1 Syntaxin-like protein DUF2373 PF10180.9 GAP83282.1 - 0.014 15.3 2.8 0.036 13.9 2.8 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.11 GAP83282.1 - 0.017 15.2 3.9 0.017 15.2 3.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Sec5 PF15469.6 GAP83282.1 - 0.048 13.5 9.3 0.075 12.8 0.8 2.7 3 0 0 3 3 3 0 Exocyst complex component Sec5 Cep57_MT_bd PF06657.13 GAP83282.1 - 0.13 12.7 10.3 3.6 8.1 2.1 3.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Nnf1 PF03980.14 GAP83282.1 - 1.3 9.5 11.1 2.2 8.7 9.2 2.4 1 1 1 2 2 2 0 Nnf1 MerR-DNA-bind PF09278.11 GAP83282.1 - 3.2 8.4 12.2 4.5 7.9 1.7 3.2 2 1 1 3 3 3 0 MerR, DNA binding Cob_adeno_trans PF01923.18 GAP83282.1 - 6.6 6.9 6.2 29 4.7 5.9 2.2 1 1 0 1 1 1 0 Cobalamin adenosyltransferase FlaC_arch PF05377.11 GAP83282.1 - 6.8 7.2 6.7 51 4.4 0.0 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) 5_3_exonuc PF01367.20 GAP83282.1 - 8.8 7.0 7.1 14 6.4 1.2 2.7 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Tyr_Deacylase PF02580.16 GAP83283.1 - 6e-52 176.0 0.3 6.9e-52 175.8 0.3 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Yippee-Mis18 PF03226.14 GAP83284.1 - 5.1e-16 58.8 0.0 7e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 GAP83284.1 - 0.00056 20.1 0.5 0.0021 18.3 0.2 1.8 2 0 0 2 2 2 1 C-terminal domain of RIG-I DNA_RNApol_7kD PF03604.13 GAP83284.1 - 0.35 10.6 1.8 2.6 7.8 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Peptidase_M48 PF01435.18 GAP83287.1 - 4.3e-39 134.3 0.0 6.2e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 SpecificRecomb PF10136.9 GAP83287.1 - 0.11 10.8 0.3 0.16 10.2 0.3 1.1 1 0 0 1 1 1 0 Site-specific recombinase Ank_2 PF12796.7 GAP83288.1 - 9.3e-111 362.6 34.0 6.4e-21 74.7 0.3 7.1 1 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP83288.1 - 9.4e-58 191.5 14.9 3.9e-11 43.0 0.2 10.3 2 1 9 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 GAP83288.1 - 2.9e-56 185.6 31.2 2e-06 28.0 0.3 12.2 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.6 GAP83288.1 - 9.9e-54 179.1 10.9 2.9e-09 37.3 0.1 9.7 3 3 7 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP83288.1 - 2.1e-51 165.9 23.2 7.2e-05 22.9 0.0 12.2 13 0 0 13 13 11 11 Ankyrin repeat PEGA PF08308.11 GAP83288.1 - 1.7e-07 31.0 4.3 1.5 8.7 0.0 6.1 6 0 0 6 6 6 3 PEGA domain GATase_7 PF13537.6 GAP83288.1 - 0.00039 20.3 0.0 8.8 6.3 0.0 4.7 3 1 1 4 4 4 1 Glutamine amidotransferase domain HET-s_218-289 PF11558.8 GAP83288.1 - 0.0025 17.8 0.0 0.98 9.5 0.0 3.0 2 0 0 2 2 2 1 Het-s 218-289 Sigma_M_inh PF17453.2 GAP83288.1 - 0.072 13.5 1.2 74 3.9 0.0 4.3 3 1 3 6 6 6 0 Sigma-M inhibitor Shigella_OspC PF06128.11 GAP83288.1 - 0.11 12.2 2.4 35 4.0 0.0 4.6 2 2 2 5 5 5 0 Shigella flexneri OspC protein Zn_clus PF00172.18 GAP83288.1 - 0.3 11.2 8.1 0.52 10.5 8.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyt-b5 PF00173.28 GAP83289.1 - 1.2e-20 73.5 0.2 1.3e-20 73.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 GAP83289.1 - 0.013 15.6 0.0 0.88 9.7 0.0 2.1 1 1 1 2 2 2 0 V-ATPase subunit H EFP_N PF08207.12 GAP83289.1 - 0.024 14.7 0.1 0.047 13.7 0.1 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain TPP_enzyme_C PF02775.21 GAP83289.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain dCMP_cyt_deam_1 PF00383.23 GAP83290.1 - 6e-26 90.3 1.9 7.9e-26 89.9 1.9 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAP83290.1 - 2.3e-09 37.1 0.1 3.5e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase TSA PF03249.13 GAP83290.1 - 0.036 12.9 0.1 0.047 12.5 0.1 1.1 1 0 0 1 1 1 0 Type specific antigen ATG7_N PF16420.5 GAP83291.1 - 3.2e-102 342.2 0.0 4.1e-102 341.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 GAP83291.1 - 3.9e-42 144.3 0.0 6.1e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 GAP83291.1 - 0.14 12.2 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AbiEii PF08843.11 GAP83292.1 - 0.065 13.2 0.1 0.32 10.9 0.1 1.9 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system MFS_1 PF07690.16 GAP83293.1 - 1.2e-35 123.1 54.9 3.4e-30 105.2 35.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP83293.1 - 2.8e-21 75.9 17.6 1.2e-17 63.9 5.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DnaJ PF00226.31 GAP83294.1 - 8.5e-05 22.6 0.0 0.43 10.8 0.0 2.2 2 0 0 2 2 2 2 DnaJ domain F-box PF00646.33 GAP83295.1 - 0.00098 18.9 0.1 0.0036 17.2 0.0 2.0 2 0 0 2 2 2 1 F-box domain GSK-3_bind PF05350.12 GAP83295.1 - 0.002 17.5 2.6 0.27 10.5 0.3 2.2 2 0 0 2 2 2 2 Glycogen synthase kinase-3 binding F-box-like PF12937.7 GAP83295.1 - 0.004 17.0 2.8 0.13 12.2 0.1 2.8 2 0 0 2 2 2 2 F-box-like FA_desaturase PF00487.24 GAP83296.1 - 1.5e-27 97.1 17.2 1.5e-27 97.1 17.2 1.5 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 GAP83296.1 - 3.5e-18 64.8 0.5 6.2e-18 64.0 0.5 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 GAP83297.1 - 3.9e-24 84.6 0.2 8.4e-24 83.5 0.2 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.8 GAP83297.1 - 0.023 14.9 0.4 0.073 13.3 0.0 2.0 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF756 PF05506.12 GAP83297.1 - 0.091 13.7 0.0 0.24 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF756) Ycf9 PF01737.17 GAP83297.1 - 0.31 11.0 5.2 2.3 8.1 0.0 2.7 3 0 0 3 3 3 0 YCF9 UBX PF00789.20 GAP83298.1 - 6.4e-05 23.1 0.0 0.00021 21.4 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 GAP83298.1 - 0.00097 19.0 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 GAP83298.1 - 0.06 13.7 0.9 0.11 12.8 0.1 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SOBP PF15279.6 GAP83298.1 - 1 9.9 4.3 1.2 9.6 4.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.14 GAP83298.1 - 2.1 6.5 15.6 2.5 6.3 15.6 1.1 1 0 0 1 1 1 0 CDC45-like protein FapA PF03961.13 GAP83298.1 - 2.3 6.7 18.4 3.2 6.3 18.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_11 PF13086.6 GAP83298.1 - 2.3 7.9 14.7 3.6 7.3 14.7 1.4 1 0 0 1 1 1 0 AAA domain GAGA_bind PF06217.12 GAP83298.1 - 3.7 7.8 13.5 5.1 7.3 13.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family V_ATPase_I PF01496.19 GAP83298.1 - 5.3 4.8 9.1 5.7 4.7 9.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 GAP83298.1 - 6.9 5.2 5.6 8.4 4.9 5.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_60s PF00428.19 GAP83299.1 - 2.1e-26 92.3 7.8 2.9e-26 91.9 7.8 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.9 GAP83300.1 - 4.1e-40 137.5 0.1 6.7e-25 88.2 0.0 4.5 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) Q_salvage PF10343.9 GAP83300.1 - 0.04 13.5 0.2 0.061 12.9 0.2 1.2 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family NPV_P10 PF05531.12 GAP83300.1 - 0.076 13.5 3.1 2.3 8.8 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2920 PF11144.8 GAP83300.1 - 0.13 11.4 0.4 91 2.0 0.0 3.5 3 1 0 4 4 4 0 Protein of unknown function (DUF2920) Snapin_Pallidin PF14712.6 GAP83300.1 - 0.17 12.3 1.7 10 6.6 0.4 3.7 3 1 1 4 4 4 0 Snapin/Pallidin COG2 PF06148.11 GAP83300.1 - 0.17 12.0 1.8 0.42 10.7 0.5 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RPW8 PF05659.11 GAP83300.1 - 0.29 10.8 2.8 8.6 6.1 0.5 2.5 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4201 PF13870.6 GAP83300.1 - 5.9 6.6 7.3 0.89 9.3 1.9 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) YCII PF03795.14 GAP83301.1 - 0.00038 20.8 0.0 0.00051 20.4 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain SP_C-Propep PF08999.10 GAP83302.1 - 0.0055 16.5 1.9 0.0073 16.1 1.9 1.3 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide AMP-binding PF00501.28 GAP83303.1 - 3e-85 286.4 0.0 3.7e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP83303.1 - 1.8e-15 57.7 0.0 4.6e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 GAP83303.1 - 2.9e-05 23.1 0.0 0.0004 19.4 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter G-patch PF01585.23 GAP83304.1 - 5.7e-13 48.5 1.1 1.4e-12 47.3 1.1 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 GAP83304.1 - 0.00053 19.7 0.0 0.0018 18.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Recep_L_domain PF01030.24 GAP83305.1 - 7.3e-11 42.2 1.4 0.0053 16.9 0.0 3.3 2 1 1 3 3 3 3 Receptor L domain Ecm33 PF12454.8 GAP83305.1 - 0.0048 17.0 0.3 0.016 15.4 0.3 2.0 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Tannase PF07519.11 GAP83306.1 - 1.1e-99 334.5 0.5 1.3e-99 334.3 0.5 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase cIII PF08134.11 GAP83306.1 - 0.12 12.2 0.0 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 cIII protein family HhH-GPD PF00730.25 GAP83307.1 - 2.8e-12 47.1 0.0 1.1e-11 45.2 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Anp1 PF03452.14 GAP83308.1 - 1.5e-109 365.5 0.0 1.9e-109 365.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 UCR_14kD PF02271.16 GAP83309.1 - 9.4e-43 144.3 0.3 1.4e-42 143.7 0.3 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 GAP83310.1 - 1.8e-63 210.4 5.1 9.4e-22 76.8 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_2 PF00891.18 GAP83312.1 - 1.7e-19 70.0 0.0 2.8e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 GAP83312.1 - 0.00034 20.6 0.1 0.00084 19.3 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 GAP83312.1 - 0.0057 17.0 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator Dimerisation2 PF16864.5 GAP83312.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain RVT_1 PF00078.27 GAP83315.1 - 1.2e-10 41.3 0.7 7.8e-10 38.6 0.3 2.4 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CRISPR_Cas9_WED PF18061.1 GAP83315.1 - 0.066 13.3 0.9 0.31 11.1 0.1 2.4 2 0 0 2 2 2 0 CRISPR-Cas9 WED domain KilA-N PF04383.13 GAP83317.1 - 0.00068 19.5 0.0 0.012 15.5 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain FeS PF04060.13 GAP83318.1 - 0.051 13.2 0.1 0.79 9.4 0.0 2.1 2 0 0 2 2 2 0 Putative Fe-S cluster BRCT_2 PF16589.5 GAP83319.1 - 1.5e-08 34.9 0.0 2.9e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 GAP83319.1 - 0.00061 19.7 0.5 0.002 18.0 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 GAP83319.1 - 0.0017 18.6 0.0 0.0037 17.5 0.0 1.6 1 1 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 GAP83319.1 - 0.0034 17.7 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain APH PF01636.23 GAP83323.1 - 7.4e-12 45.7 0.4 2.5e-09 37.4 0.4 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP83323.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 GAP83323.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1236 PF06823.12 GAP83323.1 - 0.029 14.2 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1236) Pkinase PF00069.25 GAP83323.1 - 0.1 11.9 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain Prenylcys_lyase PF07156.14 GAP83324.1 - 1.7e-13 50.5 0.0 5.6e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 GAP83324.1 - 2.9e-07 30.1 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 GAP83324.1 - 3e-07 30.3 0.9 1.4e-06 28.1 0.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAP83324.1 - 1.4e-06 28.4 0.4 2.4e-05 24.4 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAP83324.1 - 1.6e-06 28.3 0.0 4.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP83324.1 - 0.00026 20.3 0.0 0.0067 15.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAP83324.1 - 0.0022 17.3 0.2 0.027 13.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 GAP83324.1 - 0.0025 17.1 0.1 0.0046 16.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 GAP83324.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 MCRA family Pyr_redox PF00070.27 GAP83324.1 - 0.029 14.9 0.0 3.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP83324.1 - 0.044 13.0 0.4 0.74 9.0 0.3 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP83324.1 - 0.11 11.5 0.3 4.1 6.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Omega-toxin PF06357.11 GAP83325.1 - 3.7 7.4 5.8 0.79 9.6 0.8 2.5 2 0 0 2 2 2 0 Omega-atracotoxin ELMO_CED12 PF04727.13 GAP83326.1 - 3.3e-48 164.1 0.2 1.8e-47 161.7 0.2 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 GAP83326.1 - 1.1e-34 119.9 0.0 2.1e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 GAP83326.1 - 8.7e-15 55.0 0.0 2.1e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) zf-GRF PF06839.12 GAP83327.1 - 0.00037 20.5 0.8 0.00069 19.7 0.8 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF1772 PF08592.11 GAP83328.1 - 0.00018 21.8 14.3 0.0015 18.8 14.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) MscS_TM PF12794.7 GAP83328.1 - 0.031 13.1 0.5 0.031 13.1 0.5 1.4 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 adh_short_C2 PF13561.6 GAP83329.1 - 3e-38 131.7 0.3 4.6e-38 131.1 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP83329.1 - 4.9e-29 101.2 1.1 7.2e-29 100.6 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP83329.1 - 1e-08 35.3 1.4 3.6e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAP83329.1 - 0.046 12.8 0.1 0.065 12.4 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAP83329.1 - 0.061 12.7 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAP83329.1 - 0.066 12.7 0.1 0.1 12.0 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAP83331.1 - 1.1e-40 139.2 0.1 1.7e-40 138.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP83331.1 - 4.8e-30 104.9 0.1 7.1e-30 104.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP83331.1 - 3e-10 40.3 5.8 5.3e-09 36.2 5.8 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP83331.1 - 2.5e-08 33.7 0.3 4.2e-08 33.0 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP83331.1 - 0.00012 22.0 0.4 0.00021 21.2 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAP83331.1 - 0.00039 19.5 0.0 0.00059 18.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAP83331.1 - 0.0037 16.7 0.1 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAP83331.1 - 0.0047 16.1 0.0 0.0083 15.3 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 GAP83331.1 - 0.019 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 GAP83331.1 - 0.026 14.8 0.0 0.071 13.4 0.0 1.8 1 1 1 2 2 2 0 TrkA-N domain FtsJ PF01728.19 GAP83331.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase 3HCDH_N PF02737.18 GAP83331.1 - 0.18 11.7 0.7 0.6 10.0 0.4 1.9 1 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Indigoidine_A PF04227.12 GAP83333.1 - 5.5e-107 357.5 0.1 7.7e-107 357.0 0.1 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 GAP83333.1 - 1.4e-08 34.4 0.1 4.8e-07 29.4 0.0 3.0 2 1 0 2 2 2 1 pfkB family carbohydrate kinase WD40 PF00400.32 GAP83334.1 - 8.5e-08 32.8 0.2 0.23 12.4 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP83334.1 - 1.4e-06 28.5 0.1 0.3 11.4 0.0 5.3 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAP83334.1 - 0.00096 19.0 0.2 0.94 9.5 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF3328 PF11807.8 GAP83338.1 - 0.024 14.4 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF4231 PF14015.6 GAP83338.1 - 0.14 12.7 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF1180 PF06679.12 GAP83338.1 - 1.1 9.7 6.7 0.41 11.1 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) MFS_1 PF07690.16 GAP83339.1 - 1.2e-20 73.8 35.3 5.7e-20 71.5 32.2 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Aconitase PF00330.20 GAP83340.1 - 1.4e-132 443.0 0.0 2.3e-132 442.3 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAP83340.1 - 2.2e-35 121.8 0.0 4.9e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 GAP83340.1 - 0.19 10.4 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Fungal_trans PF04082.18 GAP83341.1 - 8.7e-11 41.4 0.6 7.5e-10 38.3 0.2 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP83341.1 - 5.5e-10 39.2 8.2 5.5e-10 39.2 8.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.14 GAP83342.1 - 4.7e-13 49.6 4.9 4.6e-11 43.0 2.3 2.0 1 1 0 2 2 2 2 Amidohydrolase RraA-like PF03737.15 GAP83343.1 - 2.6e-32 112.1 0.0 3.1e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Abhydrolase_3 PF07859.13 GAP83344.1 - 2.1e-54 184.6 0.2 2.7e-54 184.2 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP83344.1 - 1.4e-06 27.9 0.0 0.0019 17.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 GAP83344.1 - 1.2e-05 24.4 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 GAP83344.1 - 0.009 15.6 0.0 0.03 13.9 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 GAP83344.1 - 0.035 12.8 0.0 0.059 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 GAP83344.1 - 8.6 6.9 14.9 11 6.6 14.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-C2H2 PF00096.26 GAP83346.1 - 3.6e-13 49.2 11.4 3.6e-06 27.1 2.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP83346.1 - 4.7e-09 36.3 1.8 1.9e-07 31.2 0.2 5.0 6 0 0 6 6 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP83346.1 - 6.7e-09 35.8 10.2 0.0004 21.0 1.5 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAP83346.1 - 3.1e-08 33.4 5.4 0.00032 20.6 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP83346.1 - 7.9e-06 26.0 1.9 0.087 13.1 0.1 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP83346.1 - 3.4e-05 24.1 0.8 0.013 15.9 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 GAP83346.1 - 0.0043 16.8 4.8 0.41 10.5 0.7 3.6 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-Di19 PF05605.12 GAP83346.1 - 0.071 13.4 1.5 0.17 12.2 1.5 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 GAP83346.1 - 0.079 13.5 0.9 0.19 12.3 0.9 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 GAP83346.1 - 0.3 11.6 2.4 6.9 7.2 0.3 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 GAP83346.1 - 0.73 10.1 3.4 17 5.7 0.1 2.5 1 1 1 2 2 2 0 LIM domain ADH_zinc_N PF00107.26 GAP83347.1 - 7.9e-13 48.5 0.3 1.5e-12 47.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP83347.1 - 2.9e-06 27.1 0.4 1.5e-05 24.8 0.2 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAP83347.1 - 0.14 13.2 0.1 0.27 12.3 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Trypan_PARP PF05887.11 GAP83349.1 - 0.00079 19.4 42.4 0.00079 19.4 42.4 15.4 10 7 5 17 17 17 1 Procyclic acidic repetitive protein (PARP) PP2C PF00481.21 GAP83350.1 - 7.2e-54 183.1 0.0 1.7e-53 181.9 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 GAP83350.1 - 9.9e-40 134.1 62.4 2.6e-08 33.5 1.3 9.2 4 2 3 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 GAP83350.1 - 1.7e-36 123.6 72.9 6.6e-06 26.4 1.9 12.3 8 3 3 12 12 12 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 GAP83350.1 - 9.5e-29 100.3 0.0 3.7e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 GAP83350.1 - 8.3e-21 73.4 3.2 4.5e-20 71.1 3.2 2.4 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 GAP83350.1 - 6.2e-06 26.1 57.5 6.3 7.8 0.1 15.9 17 1 0 17 17 17 2 Leucine Rich Repeat RA PF00788.23 GAP83350.1 - 1.6e-05 25.4 0.0 3.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.6 GAP83350.1 - 0.037 13.5 21.3 1.5 8.3 0.9 4.6 2 1 2 4 4 4 0 Leucine-rich repeat PorA PF11271.8 GAP83350.1 - 0.1 11.9 0.2 0.2 10.9 0.2 1.3 1 0 0 1 1 1 0 Porin PorA LRR_6 PF13516.6 GAP83350.1 - 0.16 12.1 53.0 1.7 8.9 0.0 13.0 13 0 0 13 13 13 0 Leucine Rich repeat Dynamitin PF04912.14 GAP83351.1 - 1.3e-106 357.3 8.3 1.6e-106 356.9 8.3 1.1 1 0 0 1 1 1 1 Dynamitin SKA2 PF16740.5 GAP83351.1 - 0.00066 19.4 7.2 0.33 10.7 0.1 3.3 3 0 0 3 3 3 1 Spindle and kinetochore-associated protein 2 FH2 PF02181.23 GAP83351.1 - 0.0026 16.9 8.8 0.17 11.0 0.2 3.1 3 0 0 3 3 3 2 Formin Homology 2 Domain DUF1664 PF07889.12 GAP83351.1 - 0.0076 16.3 6.6 1.8 8.6 0.4 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) HMMR_N PF15905.5 GAP83351.1 - 0.0098 15.4 9.9 0.13 11.7 0.4 3.1 3 0 0 3 3 3 1 Hyaluronan mediated motility receptor N-terminal DUF2408 PF10303.9 GAP83351.1 - 0.014 15.9 5.3 0.45 11.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Laminin_II PF06009.12 GAP83351.1 - 0.015 15.3 14.5 0.091 12.8 0.4 4.1 2 2 2 4 4 4 0 Laminin Domain II TPR_MLP1_2 PF07926.12 GAP83351.1 - 0.021 14.9 21.1 0.35 11.0 1.1 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Sipho_Gp157 PF05565.11 GAP83351.1 - 0.025 14.6 8.4 0.75 9.8 0.1 3.3 3 1 0 3 3 3 0 Siphovirus Gp157 SKA1 PF07160.12 GAP83351.1 - 0.026 14.4 6.1 1.3 8.8 0.2 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Spc7 PF08317.11 GAP83351.1 - 0.026 13.4 14.8 0.46 9.3 1.3 3.4 2 1 0 3 3 3 0 Spc7 kinetochore protein DUF2203 PF09969.9 GAP83351.1 - 0.028 15.1 7.4 8.7 7.1 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) AAA_27 PF13514.6 GAP83351.1 - 0.029 13.9 2.6 0.47 10.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain Jnk-SapK_ap_N PF09744.9 GAP83351.1 - 0.03 14.6 10.4 1.3 9.2 0.1 3.2 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Dor1 PF04124.12 GAP83351.1 - 0.035 12.8 4.1 0.63 8.7 0.1 3.0 3 0 0 3 3 3 0 Dor1-like family BLOC1_2 PF10046.9 GAP83351.1 - 0.049 13.9 9.1 6.9 7.1 0.3 3.8 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Muted PF14942.6 GAP83351.1 - 0.061 13.7 6.3 1.1 9.5 0.2 3.2 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein COG5 PF10392.9 GAP83351.1 - 0.083 13.1 7.5 0.18 12.0 0.1 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF2046 PF09755.9 GAP83351.1 - 0.091 12.0 5.9 1.1 8.4 1.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Wtap PF17098.5 GAP83351.1 - 0.092 12.7 10.6 1.2 9.1 1.7 3.1 3 0 0 3 3 3 0 WTAP/Mum2p family APG17 PF04108.12 GAP83351.1 - 0.096 11.8 7.8 1.7 7.7 0.1 2.9 2 1 1 3 3 3 0 Autophagy protein Apg17 Prominin PF05478.11 GAP83351.1 - 0.13 10.2 2.1 3 5.7 0.0 2.7 3 0 0 3 3 3 0 Prominin Phage_GP20 PF06810.11 GAP83351.1 - 0.15 11.8 11.8 0.5 10.2 0.3 3.7 3 1 0 3 3 3 0 Phage minor structural protein GP20 Spore_III_AB PF09548.10 GAP83351.1 - 0.16 12.1 7.0 1.3 9.1 0.3 3.5 4 0 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) IFT57 PF10498.9 GAP83351.1 - 0.17 10.8 8.7 0.96 8.4 0.0 3.4 4 0 0 4 4 4 0 Intra-flagellar transport protein 57 YscO PF07321.12 GAP83351.1 - 0.19 11.7 11.9 0.76 9.7 0.2 3.2 3 0 0 3 3 3 0 Type III secretion protein YscO APG6_N PF17675.1 GAP83351.1 - 0.23 12.0 16.7 4.6 7.8 0.2 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 GAP83351.1 - 0.3 11.1 5.6 4.5 7.3 0.4 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 GAP83351.1 - 0.31 11.2 8.9 6.4 7.0 0.1 3.7 3 1 0 4 4 4 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.6 GAP83351.1 - 0.34 11.4 9.9 0.54 10.7 0.1 3.9 3 1 0 3 3 3 0 Snapin/Pallidin DivIC PF04977.15 GAP83351.1 - 0.42 10.4 16.8 0.7 9.7 0.5 4.2 3 1 1 4 4 4 0 Septum formation initiator YkyA PF10368.9 GAP83351.1 - 0.49 10.0 14.2 0.22 11.2 0.3 3.3 3 1 0 3 3 3 0 Putative cell-wall binding lipoprotein TMPIT PF07851.13 GAP83351.1 - 0.49 9.6 8.9 1.7 7.8 0.4 3.0 3 0 0 3 3 3 0 TMPIT-like protein DUF1192 PF06698.11 GAP83351.1 - 0.82 9.8 12.5 1.5 8.9 0.6 3.5 4 0 0 4 4 2 0 Protein of unknown function (DUF1192) DUF948 PF06103.11 GAP83351.1 - 1 9.6 6.8 21 5.5 0.4 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 GAP83351.1 - 1.1 9.5 11.4 9 6.6 0.8 3.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain MIIP PF15734.5 GAP83351.1 - 1.2 8.5 7.6 0.27 10.7 2.7 1.9 1 1 1 2 2 2 0 Migration and invasion-inhibitory Golgin_A5 PF09787.9 GAP83351.1 - 1.3 8.4 17.8 0.75 9.2 2.1 3.2 3 0 0 3 3 3 0 Golgin subfamily A member 5 DUF724 PF05266.14 GAP83351.1 - 1.4 8.7 12.1 1.4 8.7 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF4618 PF15397.6 GAP83351.1 - 1.5 8.2 9.4 6.3 6.1 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) FlaC_arch PF05377.11 GAP83351.1 - 1.8 9.0 14.4 16 6.0 0.1 5.5 5 2 1 6 6 6 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 GAP83351.1 - 2.7 8.3 23.4 0.068 13.4 4.4 4.5 3 2 2 5 5 5 0 ABC transporter C-terminal domain CdvA PF18822.1 GAP83351.1 - 2.8 7.8 14.5 5.2 6.9 1.2 3.5 3 0 0 3 3 3 0 CdvA-like coiled-coil domain RmuC PF02646.16 GAP83351.1 - 3.6 6.6 11.0 17 4.4 0.2 3.1 3 0 0 3 3 3 0 RmuC family XhlA PF10779.9 GAP83351.1 - 4 7.7 11.4 1.3 9.3 0.3 3.9 3 1 1 4 4 4 0 Haemolysin XhlA Rx_N PF18052.1 GAP83351.1 - 4.4 7.7 9.2 3.4 8.0 1.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain GTP-bdg_M PF16360.5 GAP83351.1 - 5.5 7.7 12.1 0.23 12.1 1.1 3.3 4 0 0 4 4 3 0 GTP-binding GTPase Middle Region ACCA PF03255.14 GAP83351.1 - 5.8 6.8 9.5 12 5.8 0.2 3.2 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FlgN PF05130.12 GAP83351.1 - 6.1 7.4 19.0 2.8 8.4 3.4 3.1 2 1 1 3 3 3 0 FlgN protein Med11 PF10280.9 GAP83351.1 - 8.5 6.8 9.3 6.5 7.2 0.2 3.4 3 1 1 4 4 4 0 Mediator complex protein LXG PF04740.12 GAP83351.1 - 9.5 5.9 10.0 6.1 6.5 0.2 3.2 3 0 0 3 3 3 0 LXG domain of WXG superfamily RTC4 PF14474.6 GAP83352.1 - 2.2e-35 121.4 0.1 5.2e-35 120.2 0.1 1.7 1 0 0 1 1 1 1 RTC4-like domain Cu-oxidase_3 PF07732.15 GAP83355.1 - 5.1e-18 65.2 0.0 1.1e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 GAP83355.1 - 7.1e-05 23.0 0.0 0.00021 21.4 0.0 1.7 1 1 0 1 1 1 1 Multicopper oxidase Exotox-A_cataly PF09009.10 GAP83355.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Exotoxin A catalytic DUF2205 PF10224.9 GAP83356.1 - 3.5e-36 123.0 1.2 5e-36 122.5 1.2 1.2 1 0 0 1 1 1 1 Short coiled-coil protein FYVE PF01363.21 GAP83358.1 - 3e-21 75.3 0.8 3e-21 75.3 0.8 2.4 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 GAP83358.1 - 1.7e-07 31.5 5.8 1.7e-07 31.5 5.8 3.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 GAP83358.1 - 7.8e-05 22.3 5.9 7.8e-05 22.3 5.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAP83358.1 - 0.00027 20.7 4.1 0.00027 20.7 4.1 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 GAP83358.1 - 0.071 13.3 8.8 0.042 14.1 1.3 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Rad50_zn_hook PF04423.14 GAP83358.1 - 0.099 12.5 0.6 0.85 9.5 0.1 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif RINGv PF12906.7 GAP83358.1 - 3.3 7.9 8.4 3 8.0 5.0 2.5 2 0 0 2 2 2 0 RING-variant domain Lipase_GDSL_2 PF13472.6 GAP83359.1 - 3.5e-07 30.8 0.7 4.7e-07 30.4 0.7 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ABC_membrane PF00664.23 GAP83360.1 - 3.3e-82 276.2 35.3 9.1e-46 156.7 11.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAP83360.1 - 3.5e-60 202.5 0.6 8.3e-32 110.6 0.0 3.4 3 0 0 3 3 3 3 ABC transporter SMC_N PF02463.19 GAP83360.1 - 2.8e-12 46.6 3.1 0.00071 19.1 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 GAP83360.1 - 3.2e-05 22.9 0.0 0.045 12.6 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 GAP83360.1 - 3.8e-05 24.1 1.7 0.001 19.5 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAP83360.1 - 7.2e-05 23.1 0.3 0.037 14.3 0.0 3.6 3 1 0 3 3 3 1 AAA domain AP3D1 PF06375.11 GAP83360.1 - 0.0004 20.7 2.7 0.00098 19.4 2.7 1.6 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 AAA_29 PF13555.6 GAP83360.1 - 0.00047 19.8 1.2 1.1 9.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAP83360.1 - 0.0009 19.2 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 GAP83360.1 - 0.0025 18.0 1.3 2 8.7 0.2 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 GAP83360.1 - 0.0034 17.8 1.0 17 5.9 0.0 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 GAP83360.1 - 0.0064 16.3 3.4 0.12 12.2 0.0 3.6 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 GAP83360.1 - 0.01 15.6 0.9 0.53 10.0 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.6 GAP83360.1 - 0.018 14.7 0.0 0.85 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 GAP83360.1 - 0.02 14.6 0.0 0.02 14.6 0.0 2.7 2 1 1 3 3 2 0 AAA ATPase domain AAA_7 PF12775.7 GAP83360.1 - 0.034 13.6 0.2 4.1 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 GAP83360.1 - 0.047 13.3 0.0 1.2 8.8 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 GAP83360.1 - 1.6 8.7 3.6 2.7 8.0 0.0 3.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) G6PD_C PF02781.16 GAP83361.1 - 6.1e-115 383.4 0.0 9.8e-115 382.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 GAP83361.1 - 1e-60 205.4 0.0 1.9e-60 204.5 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_L35Ae PF01247.18 GAP83362.1 - 2.6e-37 126.9 0.1 2.9e-37 126.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 GAP83362.1 - 1.3e-05 25.3 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 GAP83362.1 - 0.1 12.4 0.2 0.49 10.2 0.1 2.1 2 0 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) L_lactis_RepB_C PF06430.12 GAP83362.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Lactococcus lactis RepB C-terminus DUF2406 PF10295.9 GAP83363.1 - 2.6e-25 88.9 0.7 2.6e-25 88.9 0.7 3.0 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) TFIIA PF03153.13 GAP83363.1 - 0.22 11.5 24.5 0.021 14.9 19.9 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit VMA21 PF09446.10 GAP83364.1 - 1.7e-15 56.9 9.3 2.6e-15 56.3 9.3 1.3 1 0 0 1 1 1 1 VMA21-like domain DUF1772 PF08592.11 GAP83364.1 - 0.014 15.7 0.0 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) PTP_N PF12453.8 GAP83364.1 - 0.19 11.5 1.5 0.47 10.2 1.5 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Pribosyl_synth PF14572.6 GAP83365.1 - 1.8e-40 138.9 4.7 1e-35 123.4 0.8 2.7 3 1 1 4 4 4 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 GAP83365.1 - 4.7e-27 94.2 0.7 2.5e-18 66.1 0.0 3.4 3 1 0 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 GAP83365.1 - 3.1e-16 59.3 0.5 5.8e-16 58.4 0.5 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_hydro_42C PF08533.10 GAP83365.1 - 0.094 12.5 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain SNF2_N PF00176.23 GAP83366.1 - 6.7e-51 173.0 0.3 1.2e-50 172.3 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP83366.1 - 1.9e-11 44.3 0.0 4.6e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Transketolase_C PF02780.20 GAP83366.1 - 0.19 11.6 0.1 0.49 10.3 0.1 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain SSPI PF14098.6 GAP83367.1 - 0.061 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Small, acid-soluble spore protein I DUF5585 PF17823.1 GAP83367.1 - 0.12 11.3 0.1 0.16 10.9 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5585) G-patch PF01585.23 GAP83368.1 - 2.7e-05 24.0 0.0 0.0001 22.1 0.0 2.1 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAP83368.1 - 0.0038 17.3 0.0 0.0038 17.3 0.0 3.8 4 1 0 4 4 4 1 G-patch domain DUF2981 PF11200.8 GAP83368.1 - 0.58 9.9 3.2 0.85 9.3 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Period_C PF12114.8 GAP83369.1 - 0.0081 15.8 0.2 0.011 15.3 0.2 1.1 1 0 0 1 1 1 1 Period protein 2/3C-terminal region NMO PF03060.15 GAP83370.1 - 1.4e-16 60.9 0.4 4.5e-15 55.9 0.2 2.1 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 GAP83370.1 - 0.00037 19.6 0.0 0.00043 19.4 0.0 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TM1506 PF08973.10 GAP83370.1 - 0.11 12.2 0.2 3.2 7.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1893) RhoGAP PF00620.27 GAP83372.1 - 4.3e-44 150.0 0.4 1e-43 148.8 0.4 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 GAP83372.1 - 3e-12 47.0 0.0 6.2e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF3450 PF11932.8 GAP83372.1 - 0.0025 17.2 1.8 0.0061 15.9 1.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) PH_8 PF15409.6 GAP83372.1 - 0.0093 16.2 0.0 0.043 14.1 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain bZIP_2 PF07716.15 GAP83373.1 - 7.5e-10 38.8 5.2 7.5e-10 38.8 5.2 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 GAP83373.1 - 1.1e-07 31.8 6.7 1.1e-07 31.8 6.7 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 GAP83373.1 - 0.00019 21.9 3.3 0.00039 20.9 3.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor SR-25 PF10500.9 GAP83373.1 - 0.0022 17.6 5.5 0.003 17.2 5.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Glyco_hydro_18 PF00704.28 GAP83374.1 - 2.8e-21 76.6 0.3 3.5e-21 76.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 COS PF18568.1 GAP83374.1 - 0.048 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain SoxE PF06525.11 GAP83374.1 - 0.065 12.7 0.1 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Sulfocyanin (SoxE) domain Amidoligase_2 PF12224.8 GAP83375.1 - 3.1e-11 43.4 0.0 2.8e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Putative amidoligase enzyme DUF629 PF04780.12 GAP83375.1 - 0.14 10.7 0.0 0.29 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Reprolysin_4 PF13583.6 GAP83376.1 - 0.009 15.7 0.5 0.014 15.1 0.2 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Kinesin PF00225.23 GAP83377.1 - 7.9e-60 202.5 0.0 1.3e-59 201.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAP83377.1 - 9.2e-26 90.6 0.0 2.1e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding ABC_tran_Xtn PF12848.7 GAP83377.1 - 1.7 8.7 12.4 1.6 8.8 1.0 3.3 2 1 1 3 3 3 0 ABC transporter Golgin_A5 PF09787.9 GAP83377.1 - 2.4 7.6 9.8 0.094 12.2 2.7 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 OmpH PF03938.14 GAP83377.1 - 6 7.2 13.6 0.048 14.0 4.8 2.0 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Glyco_hydro_53 PF07745.13 GAP83378.1 - 5.9e-94 314.8 0.1 1.5e-93 313.5 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 53 TMEM154 PF15102.6 GAP83378.1 - 0.0067 16.3 0.0 0.0067 16.3 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family Amnionless PF14828.6 GAP83378.1 - 0.016 14.1 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 GAP83378.1 - 0.042 14.7 0.0 0.13 13.2 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 GAP83378.1 - 0.049 13.9 2.5 48 4.3 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) SARAF PF06682.12 GAP83378.1 - 0.26 10.9 0.0 0.26 10.9 0.0 2.7 2 1 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Glyco_hydro_17 PF00332.18 GAP83379.1 - 2e-05 24.3 0.2 2.8e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 ArabFuran-catal PF09206.11 GAP83380.1 - 3.2e-152 506.3 11.5 4.5e-152 505.9 11.5 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 GAP83380.1 - 1.7e-56 190.1 2.7 3e-56 189.3 2.7 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain HSP20 PF00011.21 GAP83381.1 - 8.7e-21 74.0 0.4 2.5e-14 53.3 0.2 2.6 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 GAP83381.1 - 7.7e-05 22.2 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA INO80_Ies4 PF08193.11 GAP83381.1 - 0.077 13.0 4.8 0.14 12.2 4.8 1.3 1 0 0 1 1 1 0 INO80 complex subunit Ies4 DUF1387 PF07139.11 GAP83381.1 - 0.14 11.9 2.8 0.17 11.6 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) YTH PF04146.15 GAP83382.1 - 1.5e-62 210.4 0.0 6.4e-62 208.4 0.0 1.9 2 0 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 GAP83382.1 - 0.015 15.1 0.0 0.049 13.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.26 GAP83383.1 - 4e-30 104.7 0.2 8.9e-30 103.6 0.2 1.5 1 1 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.27 GAP83384.1 - 8.2e-38 130.6 0.1 2.9e-35 122.3 0.1 3.0 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 GAP83384.1 - 8.4e-22 77.5 0.1 2e-21 76.3 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) LacY_symp PF01306.19 GAP83384.1 - 0.088 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 LacY proton/sugar symporter SusD-like_3 PF14322.6 GAP83384.1 - 0.14 12.5 0.1 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 Starch-binding associating with outer membrane Trypsin_2 PF13365.6 GAP83385.1 - 0.004 18.1 0.0 0.06 14.2 0.0 3.0 1 1 1 2 2 2 1 Trypsin-like peptidase domain YabA PF06156.13 GAP83385.1 - 0.022 15.4 1.9 0.073 13.7 1.9 1.9 1 0 0 1 1 1 0 Initiation control protein YabA CENP-K PF11802.8 GAP83385.1 - 1.6 8.3 5.0 3.4 7.2 5.0 1.5 1 1 0 1 1 1 0 Centromere-associated protein K DUF5326 PF17260.2 GAP83386.1 - 0.036 14.2 1.4 0.064 13.4 1.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5326) BLF1 PF17752.1 GAP83386.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Burkholderia lethal factor 1 Cation_efflux PF01545.21 GAP83387.1 - 9.6e-23 80.9 11.8 1.2e-22 80.6 11.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAP83387.1 - 0.00013 22.0 0.1 0.00027 21.0 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4271 PF14093.6 GAP83387.1 - 0.7 9.8 7.0 0.1 12.5 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) YL1 PF05764.13 GAP83388.1 - 0.012 15.7 2.4 0.012 15.7 2.4 2.3 2 0 0 2 2 2 0 YL1 nuclear protein FAM70 PF14967.6 GAP83388.1 - 2.7 7.4 4.0 10 5.5 4.0 2.0 1 0 0 1 1 1 0 FAM70 protein DMRL_synthase PF00885.19 GAP83389.1 - 2.5e-53 179.7 0.0 3.1e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DNA_mis_repair PF01119.19 GAP83390.1 - 7.9e-10 38.4 0.0 1.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Nha1_C PF08619.10 GAP83390.1 - 2.9 7.0 8.8 0.058 12.6 0.6 1.9 1 1 1 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus SLATT_fungal PF18142.1 GAP83391.1 - 2.2e-32 111.6 0.7 4.5e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain Apolipoprotein PF01442.18 GAP83391.1 - 7.1e-05 22.8 18.4 0.00042 20.3 11.2 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain ETF_alpha PF00766.19 GAP83391.1 - 0.016 15.2 1.1 0.35 10.9 0.1 3.2 3 0 0 3 3 3 0 Electron transfer flavoprotein FAD-binding domain DUF3584 PF12128.8 GAP83391.1 - 0.094 10.2 6.9 0.12 9.8 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4351 PF14261.6 GAP83391.1 - 0.094 12.8 0.3 0.35 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) PV-1 PF06637.11 GAP83391.1 - 0.18 10.6 1.9 0.29 9.9 1.9 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) AIG2_2 PF13772.6 GAP83392.1 - 3.3e-05 24.2 0.0 0.0031 17.9 0.0 2.3 2 0 0 2 2 2 2 AIG2-like family Mito_fiss_reg PF05308.11 GAP83392.1 - 0.52 10.4 10.4 0.45 10.6 1.5 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator NAD_Gly3P_dh_N PF01210.23 GAP83393.1 - 5.8e-48 162.8 0.1 1.9e-47 161.2 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 GAP83393.1 - 2.4e-41 141.3 0.3 4.3e-41 140.5 0.3 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 GAP83393.1 - 0.012 16.1 0.0 3.8 8.1 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent hDGE_amylase PF14701.6 GAP83394.1 - 1.9e-173 577.6 0.0 2.4e-173 577.3 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 GAP83394.1 - 1.1e-90 304.3 2.2 3.8e-89 299.3 0.2 2.7 2 1 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 GAP83394.1 - 6.7e-29 101.3 6.6 5.5e-11 42.6 0.5 4.3 1 1 3 4 4 4 4 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 GAP83394.1 - 1.2e-28 99.1 0.0 2.5e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Ctr PF04145.15 GAP83396.1 - 1.3e-26 94.0 10.5 5.4e-26 92.0 10.5 1.8 1 1 0 1 1 1 1 Ctr copper transporter family NUDIX PF00293.28 GAP83397.1 - 2.7e-08 33.9 0.1 9.6e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain DUF1840 PF08895.11 GAP83397.1 - 0.44 10.9 3.3 1.1 9.7 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Roughex PF06020.11 GAP83397.1 - 1.1 8.2 3.9 1.6 7.8 3.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein FAM70 PF14967.6 GAP83397.1 - 7.8 5.9 6.8 11 5.3 6.8 1.2 1 0 0 1 1 1 0 FAM70 protein Pkinase PF00069.25 GAP83399.1 - 2.3e-77 259.9 0.0 3e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP83399.1 - 1.6e-36 125.9 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 GAP83399.1 - 3.2e-16 59.4 0.1 7.1e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 GAP83399.1 - 3e-11 43.2 0.0 1.2e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 GAP83399.1 - 2.6e-09 37.3 0.0 7e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 GAP83399.1 - 5.8e-06 25.3 0.0 9.2e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAP83399.1 - 0.00047 19.6 0.2 0.0011 18.3 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAP83399.1 - 0.0024 17.5 0.1 0.98 9.0 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 GAP83399.1 - 0.0069 15.4 0.1 0.0099 14.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 GAP83399.1 - 0.03 13.3 0.1 0.077 11.9 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 GAP83399.1 - 0.031 13.8 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2961 PF11175.8 GAP83399.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) APH PF01636.23 GAP83399.1 - 0.11 12.4 0.1 0.56 10.1 0.1 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family E1-E2_ATPase PF00122.20 GAP83400.1 - 2.3e-45 154.4 0.0 2.3e-45 154.4 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAP83400.1 - 1.2e-36 126.1 6.2 8e-20 71.3 1.8 2.8 1 1 1 2 2 2 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAP83400.1 - 5e-22 79.2 0.1 4.9e-21 76.0 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAP83400.1 - 1.2e-17 63.4 0.0 2.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAP83400.1 - 6.8e-13 48.5 0.0 1.4e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAP83400.1 - 0.0001 22.2 0.5 0.001 18.9 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.13 GAP83401.1 - 9.1e-35 119.2 0.0 1.7e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GAP83401.1 - 4.5e-08 32.3 0.2 1e-07 31.1 0.2 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Elongin_A PF06881.11 GAP83403.1 - 6.4e-30 103.8 0.1 6.4e-30 103.8 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ubiquitin PF00240.23 GAP83404.1 - 3.1e-24 84.5 0.1 3.5e-24 84.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAP83404.1 - 6.5e-10 38.7 0.2 7.2e-10 38.6 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAP83404.1 - 0.00059 20.2 0.0 0.00079 19.8 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAP83404.1 - 0.0017 18.4 0.1 0.0061 16.6 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 GAP83404.1 - 0.022 14.7 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAP83404.1 - 0.06 13.7 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain Band_7 PF01145.25 GAP83405.1 - 8.4e-23 81.3 3.1 1.3e-22 80.7 3.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family CSTF2_hinge PF14327.6 GAP83406.1 - 5.1e-34 116.6 2.1 5.1e-34 116.6 2.1 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 GAP83406.1 - 6.9e-22 77.1 0.0 1.3e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 GAP83406.1 - 6.7e-09 35.2 6.9 6.7e-09 35.2 6.9 3.0 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal DUF3135 PF11333.8 GAP83406.1 - 0.048 13.9 1.6 0.048 13.9 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) RRM_7 PF16367.5 GAP83406.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif L1R_F9L PF02442.17 GAP83406.1 - 0.1 12.4 0.3 0.22 11.4 0.1 1.6 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses Spo7_2_N PF15407.6 GAP83406.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 CorA PF01544.18 GAP83407.1 - 9.7e-41 140.0 0.4 1.4e-39 136.2 0.4 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Osmo_CC PF08946.10 GAP83407.1 - 0.088 13.1 0.2 0.24 11.7 0.2 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Amino_oxidase PF01593.24 GAP83408.1 - 4.4e-20 72.4 0.0 5.6e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAP83408.1 - 3.2e-11 43.3 0.7 1.1e-10 41.5 0.6 2.1 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP83408.1 - 7.9e-09 35.5 0.6 1.5e-05 24.8 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP83408.1 - 3.4e-06 26.5 0.0 0.00075 18.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP83408.1 - 0.00077 18.8 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 GAP83408.1 - 0.0083 16.1 0.0 0.12 12.4 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAP83408.1 - 0.019 15.5 0.2 0.24 12.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 GAP83408.1 - 0.032 13.0 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 MCRA family zf-CCCH_2 PF14608.6 GAP83409.1 - 9.7e-12 44.9 58.5 6.2e-05 23.3 12.4 5.4 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 GAP83409.1 - 0.0017 18.6 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) p450 PF00067.22 GAP83410.1 - 3.1e-58 197.6 0.0 2.2e-57 194.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.22 GAP83411.1 - 2.8e-84 283.5 0.0 3.5e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 GAP83411.1 - 1.6e-25 90.4 0.0 2.7e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 GAP83411.1 - 1.7e-07 32.0 0.0 4.2e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 Aldedh PF00171.22 GAP83412.1 - 4.6e-184 612.2 0.3 5.3e-184 612.0 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 GAP83412.1 - 0.0046 16.4 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Aminotran_1_2 PF00155.21 GAP83413.1 - 2.2e-18 66.6 0.0 2.9e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 GAP83413.1 - 2.1e-05 23.5 0.0 0.00024 20.0 0.0 2.1 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 GAP83413.1 - 0.056 12.7 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_16 PF00722.21 GAP83414.1 - 1.5e-37 128.8 0.3 2.6e-37 128.0 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I PF01028.20 GAP83416.1 - 3.4e-96 321.0 7.1 3.4e-96 321.0 7.1 1.9 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 GAP83416.1 - 3.5e-96 320.8 2.2 3.5e-96 320.8 2.2 2.9 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 GAP83416.1 - 2.7e-30 104.1 0.2 8.7e-30 102.5 0.2 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.19 GAP83417.1 - 1.3e-79 267.8 1.7 1.6e-79 267.5 1.7 1.0 1 0 0 1 1 1 1 ATP synthase Amino_oxidase PF01593.24 GAP83418.1 - 1.3e-84 285.1 0.1 5.8e-83 279.7 0.1 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 GAP83418.1 - 1.7e-12 47.5 0.0 5.5e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 GAP83418.1 - 3e-07 30.6 0.3 7.2e-07 29.3 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.10 GAP83418.1 - 1e-06 29.2 5.1 2.3e-06 28.1 5.1 1.5 1 0 0 1 1 1 1 HMG-box domain Pyr_redox_2 PF07992.14 GAP83418.1 - 5.2e-06 25.9 0.1 0.0035 16.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HMG_box PF00505.19 GAP83418.1 - 9e-05 22.8 6.2 9e-05 22.8 6.2 2.4 2 1 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.24 GAP83418.1 - 0.0027 17.4 0.1 0.0069 16.0 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Sec1 PF00995.23 GAP83419.1 - 7.5e-127 425.0 0.0 8.5e-127 424.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family UQ_con PF00179.26 GAP83420.1 - 8.3e-27 93.6 0.0 9.6e-27 93.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAP83420.1 - 3.9e-07 29.8 0.0 4.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GAP83420.1 - 0.0065 16.3 0.0 0.0093 15.8 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 GAP83420.1 - 0.011 16.0 0.1 0.014 15.6 0.1 1.4 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 GAP83420.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 GMP_synt_C PF00958.22 GAP83421.1 - 0.19 11.8 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 GMP synthase C terminal domain Pkinase PF00069.25 GAP83422.1 - 4.1e-70 236.2 0.0 6.1e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP83422.1 - 4e-34 118.1 0.0 5.7e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP83422.1 - 1.2e-06 28.0 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAP83422.1 - 9.6e-05 21.8 0.1 0.00016 21.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 GAP83422.1 - 0.0012 18.4 0.1 0.0085 15.6 0.0 2.4 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 GAP83422.1 - 0.0069 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase KTI12 PF08433.10 GAP83423.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF4172 PF13776.6 GAP83424.1 - 0.0078 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4172) Med14 PF08638.11 GAP83425.1 - 3e-63 212.7 0.1 5.2e-63 211.9 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 ArfGap PF01412.18 GAP83427.1 - 3.6e-33 114.1 0.2 1.7e-32 111.9 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 GAP83427.1 - 2.5e-22 79.8 14.6 4e-22 79.1 14.6 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 GAP83427.1 - 3.9e-11 43.4 1.2 6.4e-11 42.7 0.1 1.9 2 0 0 2 2 2 1 PH domain FTO_CTD PF12934.7 GAP83427.1 - 0.11 12.3 1.4 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 FTO C-terminal domain DUF4358 PF14270.6 GAP83427.1 - 0.11 12.8 3.7 1.8 8.9 1.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) APG6_N PF17675.1 GAP83427.1 - 5.6 7.5 18.3 11 6.5 5.4 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Hemocyanin_C PF03723.14 GAP83428.1 - 0.064 12.6 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Hemocyanin, ig-like domain Membr_traf_MHD PF10540.9 GAP83429.1 - 5.3e-17 62.4 2.4 4.6e-08 33.4 0.3 3.5 3 1 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 GAP83429.1 - 1.3e-15 57.5 0.0 2.8e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 GAP83429.1 - 9e-06 24.5 0.4 9e-06 24.5 0.4 1.8 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) HAMP PF00672.25 GAP83431.1 - 4.4e-39 132.7 14.1 9.9e-08 32.2 0.3 7.4 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.26 GAP83431.1 - 1.5e-31 109.2 0.0 4.8e-31 107.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAP83431.1 - 4.7e-26 91.2 0.2 3.1e-25 88.5 0.3 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAP83431.1 - 2.1e-17 62.9 3.0 8.3e-17 61.0 0.6 3.4 4 0 0 4 4 3 1 His Kinase A (phospho-acceptor) domain GLE1 PF07817.13 GAP83431.1 - 0.0019 17.4 5.3 1.4 8.1 0.0 4.3 2 1 2 4 4 4 2 GLE1-like protein Fib_alpha PF08702.10 GAP83431.1 - 0.0027 17.9 31.8 0.064 13.4 0.4 6.7 6 1 0 6 6 6 2 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 GAP83431.1 - 0.0039 16.8 0.2 0.0039 16.8 0.2 5.1 3 3 2 5 5 5 2 Domain of unknown function (DUF4795) DUF948 PF06103.11 GAP83431.1 - 0.04 14.2 48.5 1.4 9.2 0.1 9.9 4 2 4 8 8 8 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.6 GAP83431.1 - 0.26 9.9 20.8 0.18 10.4 7.0 3.1 2 1 1 3 3 3 0 AAA domain GhoS PF11080.8 GAP83431.1 - 0.26 11.3 3.9 0.72 9.9 0.0 3.5 4 0 0 4 4 4 0 Endoribonuclease GhoS DUF3829 PF12889.7 GAP83431.1 - 1.1 8.6 14.1 2.6 7.4 0.2 5.0 4 2 2 6 6 6 0 Protein of unknown function (DUF3829) DUF883 PF05957.13 GAP83431.1 - 1.5 9.4 17.4 3.7 8.2 0.4 5.6 5 1 1 6 6 5 0 Bacterial protein of unknown function (DUF883) APG6_N PF17675.1 GAP83432.1 - 0.04 14.4 0.6 0.044 14.3 0.6 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 GAP83432.1 - 0.041 13.2 0.9 0.044 13.1 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 GAP83432.1 - 0.048 12.5 0.3 0.055 12.3 0.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 GAP83432.1 - 0.1 12.8 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Haemolysin XhlA HMG_box PF00505.19 GAP83433.1 - 3.5e-17 62.6 0.5 7.9e-17 61.4 0.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAP83433.1 - 2.2e-14 53.8 0.5 5.4e-14 52.5 0.5 1.7 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 GAP83433.1 - 4.4e-10 39.9 0.0 7.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAP83433.1 - 1.5e-06 28.2 0.0 3.1e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Cnd2 PF05786.14 GAP83434.1 - 0 1012.4 7.5 0 1012.2 7.5 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 GAP83434.1 - 0.0066 16.6 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Lipase_GDSL_2 PF13472.6 GAP83434.1 - 0.25 11.7 1.2 2.1 8.7 0.0 2.9 4 0 0 4 4 4 0 GDSL-like Lipase/Acylhydrolase family Pep1_7 PF17232.2 GAP83434.1 - 0.38 11.2 2.8 1.9 9.0 2.7 2.2 2 0 0 2 2 2 0 Elicitor peptide 1-7 ADC PF06314.11 GAP83435.1 - 0.002 17.8 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Fungal_trans PF04082.18 GAP83436.1 - 3.1e-08 33.0 0.1 6e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP83436.1 - 3e-07 30.5 8.6 3e-07 30.5 8.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-MYND PF01753.18 GAP83437.1 - 0.00077 19.5 11.1 0.0014 18.7 11.1 1.4 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 GAP83437.1 - 0.12 10.2 1.7 0.18 9.7 1.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 GAP83437.1 - 0.21 11.9 10.5 0.48 10.8 10.5 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding p450 PF00067.22 GAP83439.1 - 4e-57 194.0 0.0 1.3e-41 142.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 GAP83440.1 - 1.6e-36 126.0 28.0 1.6e-36 126.0 28.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4229 PF14012.6 GAP83440.1 - 0.83 9.8 8.7 0.12 12.5 2.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Dicty_CAR PF05462.11 GAP83441.1 - 1.4e-08 34.3 9.3 1.4e-08 34.3 9.3 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 GAP83441.1 - 1.6e-08 34.1 10.3 2.9e-08 33.3 10.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 GAP83441.1 - 1.3e-06 28.4 13.2 2e-06 27.7 13.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 GAP83441.1 - 2.3e-05 23.8 3.2 3.3e-05 23.4 3.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 GAP83441.1 - 0.048 12.7 11.7 0.015 14.4 6.2 2.1 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region MFS_1 PF07690.16 GAP83442.1 - 2.9e-33 115.3 23.2 2.9e-33 115.3 23.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Nas2_N PF18265.1 GAP83443.1 - 1.7e-31 108.0 0.2 2.5e-31 107.4 0.2 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 GAP83443.1 - 2.2e-08 33.8 0.1 6e-08 32.4 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 GAP83443.1 - 2e-07 31.2 0.1 4.8e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 GAP83443.1 - 2.2e-05 24.8 0.0 5.2e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 GAP83443.1 - 0.00012 22.4 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain CENP-K PF11802.8 GAP83443.1 - 0.075 12.6 0.0 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 Centromere-associated protein K Ras PF00071.22 GAP83444.1 - 8.2e-49 165.3 0.0 9.8e-49 165.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP83444.1 - 4.4e-29 101.1 0.0 1.1e-28 99.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP83444.1 - 5.2e-10 39.0 0.0 6.9e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 GAP83444.1 - 0.00064 20.1 0.1 0.0064 16.9 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 GAP83444.1 - 0.00092 19.3 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAP83444.1 - 0.0054 16.1 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 GAP83444.1 - 0.02 14.4 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 GAP83444.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 GAP83444.1 - 0.031 14.2 0.1 9.2 6.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 GAP83444.1 - 0.033 13.3 1.9 1.4 8.0 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 GAP83444.1 - 0.075 12.7 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAP83444.1 - 0.11 12.7 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAP83444.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GAP83444.1 - 0.12 12.8 0.1 0.22 11.9 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 GAP83444.1 - 0.2 10.9 0.5 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 Septin E1-E2_ATPase PF00122.20 GAP83445.1 - 4.8e-52 176.1 5.2 2.2e-51 174.0 2.8 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAP83445.1 - 2.2e-45 154.6 5.1 2.2e-45 154.6 5.1 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAP83445.1 - 3.5e-24 86.3 2.6 2e-23 83.8 2.6 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAP83445.1 - 1.4e-20 73.2 0.0 2.6e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAP83445.1 - 1.1e-18 66.6 0.0 3.9e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAP83445.1 - 5.5e-10 39.4 2.0 9.4e-07 28.8 1.3 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAP83445.1 - 1.1e-06 29.2 0.0 3e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GAP83445.1 - 0.015 15.4 0.0 0.068 13.3 0.0 2.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GHL6 PF14871.6 GAP83445.1 - 0.14 12.3 0.0 3.3 7.9 0.0 2.8 2 1 1 3 3 3 0 Hypothetical glycosyl hydrolase 6 Proteasome PF00227.26 GAP83446.1 - 5e-43 146.8 0.0 6e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 GAP83447.1 - 5.3e-23 81.0 0.1 9.9e-23 80.1 0.1 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain Rad60-SLD PF11976.8 GAP83447.1 - 0.00013 21.7 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4950 PF16308.5 GAP83447.1 - 0.003 17.6 0.2 0.089 12.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4950) ubiquitin PF00240.23 GAP83447.1 - 0.018 14.8 0.0 0.066 13.0 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin family Ribosomal_L36e PF01158.18 GAP83448.1 - 1.9e-37 127.4 9.0 2.1e-37 127.3 9.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 GAP83448.1 - 0.071 13.2 0.6 0.085 12.9 0.6 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide RhoGEF PF00621.20 GAP83449.1 - 1.5e-24 87.3 0.0 2.4e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain SBDS PF01172.18 GAP83450.1 - 4e-23 81.3 0.5 4.8e-23 81.0 0.5 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein OPA3 PF07047.12 GAP83453.1 - 1.4e-45 154.1 0.7 1.9e-45 153.7 0.7 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) JAKMIP_CC3 PF16034.5 GAP83453.1 - 0.0036 17.3 11.2 0.024 14.6 11.2 1.9 1 1 0 1 1 1 1 JAKMIP CC3 domain TMF_TATA_bd PF12325.8 GAP83453.1 - 0.52 10.5 8.7 0.2 11.9 1.6 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Pkinase PF00069.25 GAP83454.1 - 1.7e-66 224.3 0.0 2.3e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP83454.1 - 3e-42 144.7 0.0 4.2e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 GAP83454.1 - 2.8e-06 27.4 0.0 0.0027 17.9 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 GAP83454.1 - 1.4e-05 24.6 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAP83454.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAP83454.1 - 0.01 14.6 0.1 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 GAP83454.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Sel1 PF08238.12 GAP83455.1 - 6e-38 128.4 27.9 2.5e-06 28.0 0.2 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 GAP83455.1 - 0.12 13.1 0.5 7.3 7.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Chitin_synth_2 PF03142.15 GAP83456.1 - 9.1e-289 958.4 0.2 1.2e-288 958.1 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 GAP83456.1 - 1.7e-12 47.7 2.2 5.6e-12 46.0 2.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAP83456.1 - 7.3e-11 42.4 0.0 1.4e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAP83456.1 - 0.011 15.3 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 DUF2415 PF10313.9 GAP83457.1 - 0.0027 17.6 0.0 0.0087 16.0 0.0 1.9 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 GAP83457.1 - 0.0042 17.9 3.1 0.0051 17.6 0.3 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP83457.1 - 0.013 15.8 0.0 18 5.8 0.0 4.0 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_17 PF00332.18 GAP83458.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 DUF2105 PF09878.9 GAP83459.1 - 0.039 13.7 0.3 0.044 13.5 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) RNB PF00773.19 GAP83460.1 - 5.1e-61 206.8 0.0 9.9e-61 205.9 0.0 1.5 1 1 0 1 1 1 1 RNB domain DUF1752 PF08550.10 GAP83461.1 - 5e-11 42.2 2.9 1.2e-10 41.1 2.9 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Met_10 PF02475.16 GAP83462.1 - 1.2e-70 237.4 0.0 1.5e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 GAP83462.1 - 0.073 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase 2OG-FeII_Oxy_2 PF13532.6 GAP83463.1 - 2.5e-26 93.1 0.0 1.6e-25 90.5 0.0 2.2 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily DUF3291 PF11695.8 GAP83464.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) Prenyltransf PF01255.19 GAP83464.1 - 0.088 12.3 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase DUF2415 PF10313.9 GAP83464.1 - 0.094 12.7 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Sec10 PF07393.11 GAP83465.1 - 5.9e-213 709.3 6.8 1.1e-212 708.3 6.8 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec10 Homeodomain PF00046.29 GAP83466.1 - 9.4e-15 54.2 1.9 2.2e-14 53.0 1.9 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAP83466.1 - 0.13 12.2 0.3 0.36 10.8 0.3 1.8 1 0 0 1 1 1 0 Homeobox KN domain NAD_kinase PF01513.21 GAP83467.1 - 1.6e-79 267.1 0.0 2.2e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.21 GAP83468.1 - 9.7e-11 42.3 0.0 1.8e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAP83468.1 - 0.084 12.9 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 PTPA PF03095.15 GAP83469.1 - 3.1e-111 371.7 0.0 3.6e-111 371.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ank_2 PF12796.7 GAP83471.1 - 4.6e-42 142.5 0.0 1.7e-13 51.0 0.0 6.8 4 2 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP83471.1 - 1.9e-38 130.3 0.0 8.7e-09 35.8 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP83471.1 - 1e-35 121.3 1.4 1.8e-09 37.6 0.0 8.0 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 GAP83471.1 - 3.3e-28 96.8 1.2 0.00078 19.8 0.1 10.0 9 2 1 10 10 10 5 Ankyrin repeat Ank_3 PF13606.6 GAP83471.1 - 1.9e-27 92.2 0.3 0.0026 18.1 0.0 11.1 13 0 0 13 13 13 4 Ankyrin repeat AAA_16 PF13191.6 GAP83471.1 - 3.2e-07 30.9 0.0 1.2e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GAP83471.1 - 0.00028 20.9 0.4 0.0017 18.3 0.1 2.5 2 2 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 GAP83471.1 - 0.008 16.4 0.0 0.034 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 GAP83471.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Anp1 PF03452.14 GAP83472.1 - 4.7e-107 357.3 0.0 5.6e-107 357.0 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 GAP83472.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 UQ_con PF00179.26 GAP83473.1 - 2e-28 98.8 0.0 2.2e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cgr1 PF03879.14 GAP83475.1 - 3.9e-33 114.0 30.8 4.5e-33 113.8 30.8 1.0 1 0 0 1 1 1 1 Cgr1 family ArAE_2_N PF10337.9 GAP83475.1 - 0.33 9.9 3.3 0.4 9.7 3.3 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal RR_TM4-6 PF06459.12 GAP83475.1 - 1 9.1 14.7 1.1 9.0 14.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 COX16 PF14138.6 GAP83475.1 - 6.7 7.3 11.3 12 6.5 11.3 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 HCMV_UL139 PF12507.8 GAP83476.1 - 0.0027 18.1 1.8 0.0087 16.4 1.9 1.8 1 1 0 1 1 1 1 Human Cytomegalovirus UL139 protein Fib_alpha PF08702.10 GAP83476.1 - 0.0034 17.6 4.9 0.0072 16.5 4.9 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF4559 PF15112.6 GAP83476.1 - 0.015 15.0 2.7 0.02 14.6 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) T4SS PF07996.11 GAP83476.1 - 0.036 14.5 9.3 0.052 14.0 9.0 1.4 1 1 0 1 1 1 0 Type IV secretion system proteins ZapB PF06005.12 GAP83476.1 - 0.095 13.2 6.5 1.9 9.0 0.5 2.7 2 0 0 2 2 2 0 Cell division protein ZapB DUF16 PF01519.16 GAP83476.1 - 0.36 11.3 4.2 0.67 10.5 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 CorA PF01544.18 GAP83476.1 - 0.41 9.9 5.7 2 7.7 2.5 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein CENP-H PF05837.12 GAP83476.1 - 3.1 8.2 10.5 2.4 8.6 4.7 2.9 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF3818 PF12825.7 GAP83477.1 - 4.1e-129 430.5 4.9 7e-129 429.7 4.9 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 GAP83477.1 - 1e-39 135.5 0.2 2.2e-39 134.4 0.2 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 GAP83477.1 - 6.4e-17 61.6 0.2 2.5e-15 56.5 0.0 3.3 3 1 0 3 3 3 1 PX domain Cwf_Cwc_15 PF04889.12 GAP83477.1 - 0.027 14.2 1.9 0.078 12.7 1.9 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAF1A PF12253.8 GAP83477.1 - 0.091 12.9 2.9 0.23 11.7 2.9 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A CREPT PF16566.5 GAP83477.1 - 1.9 8.6 11.0 0.038 14.2 1.1 2.7 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour FAD_binding_2 PF00890.24 GAP83478.1 - 3.7e-124 415.0 3.3 4.6e-124 414.7 3.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 GAP83478.1 - 3.4e-43 146.7 0.2 5.1e-43 146.1 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 GAP83478.1 - 1.5e-05 24.2 1.1 0.046 12.8 1.9 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 GAP83478.1 - 1.8e-05 24.2 0.1 0.0032 16.7 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP83478.1 - 0.0002 20.7 0.2 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 GAP83478.1 - 0.0028 16.9 1.6 0.0031 16.8 0.1 1.8 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 GAP83478.1 - 0.061 12.9 0.9 0.12 12.0 0.9 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF600 PF04634.12 GAP83478.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF600 adh_short_C2 PF13561.6 GAP83479.1 - 6.6e-43 146.9 1.0 8.4e-43 146.6 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP83479.1 - 1.6e-36 125.6 0.0 2e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP83479.1 - 6.1e-08 32.8 0.2 8.7e-08 32.3 0.2 1.2 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 GAP83480.1 - 3.9e-37 128.0 22.5 3.9e-37 128.0 22.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP83480.1 - 1.7e-17 63.4 2.3 1.7e-17 63.4 2.3 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAP83480.1 - 0.0052 15.3 1.9 0.012 14.1 1.9 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 GAP83480.1 - 0.023 13.0 0.8 0.34 9.1 0.8 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 GAP83481.1 - 1.2e-14 54.0 1.7 1.4e-14 53.8 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAP83481.1 - 3.5e-11 42.9 5.8 1.4e-05 25.3 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 GAP83481.1 - 3e-06 27.3 9.9 3e-06 27.3 9.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 GAP83481.1 - 0.00032 21.0 7.5 0.0017 18.7 0.7 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP83481.1 - 0.0014 19.3 13.8 0.027 15.3 1.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP83481.1 - 0.079 13.3 2.8 1.1 9.7 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 GAP83481.1 - 0.24 11.0 5.3 8.9 6.0 0.1 3.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 GAP83481.1 - 1 9.2 9.2 0.73 9.7 1.0 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 GAP83481.1 - 6.1 7.4 11.1 2.1 8.8 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ank_3 PF13606.6 GAP83482.1 - 1.6e-09 37.2 0.2 0.0051 17.2 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 GAP83482.1 - 2.2e-08 34.2 0.3 0.00066 20.0 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 GAP83482.1 - 2.9e-06 27.8 0.1 0.00014 22.3 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP83482.1 - 0.00068 20.2 0.8 0.0025 18.4 0.1 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP83482.1 - 0.056 13.8 0.1 1.5 9.2 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) BDV_P10 PF06515.11 GAP83482.1 - 0.5 10.4 0.1 0.5 10.4 0.1 2.6 3 0 0 3 3 3 0 Borna disease virus P10 protein CENP-B_dimeris PF09026.10 GAP83482.1 - 1.5 9.3 7.1 3.2 8.2 7.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SSP160 PF06933.11 GAP83482.1 - 6.7 4.8 13.9 1.6 6.8 5.8 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Beta_helix PF13229.6 GAP83483.1 - 3.7e-10 39.9 12.4 7.4e-10 38.9 12.4 1.5 1 0 0 1 1 1 1 Right handed beta helix region Chondroitinas_B PF14592.6 GAP83483.1 - 2.7e-07 29.8 0.0 5.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.11 GAP83483.1 - 0.038 13.3 0.4 0.038 13.3 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1565) MGC-24 PF05283.11 GAP83484.1 - 0.0029 18.0 3.4 0.0029 18.0 3.4 1.9 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin eIF3_subunit PF08597.10 GAP83485.1 - 4.1e-72 243.0 21.5 5.1e-72 242.7 21.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit BRF1 PF07741.13 GAP83485.1 - 0.38 11.1 17.4 0.24 11.7 9.5 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Rrn6 PF10214.9 GAP83485.1 - 1.4 7.3 11.8 2.4 6.5 11.8 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4228 PF14009.6 GAP83485.1 - 5.4 7.4 9.3 5.6 7.3 6.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) LRIF1 PF15741.5 GAP83485.1 - 5.6 5.4 11.5 0.43 9.1 6.3 1.6 2 0 0 2 2 2 0 Ligand-dependent nuclear receptor-interacting factor 1 MDM31_MDM32 PF08118.11 GAP83486.1 - 2e-249 828.6 0.0 3e-249 828.1 0.0 1.2 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.29 GAP83487.1 - 0.027 14.3 0.5 0.062 13.1 0.5 1.6 1 0 0 1 1 1 0 KH domain KH_8 PF17903.1 GAP83487.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Krr1 KH1 domain GMC_oxred_N PF00732.19 GAP83488.1 - 1.9e-27 96.4 0.0 7.8e-19 68.1 0.0 3.2 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP83488.1 - 1.2e-25 90.7 0.0 3.1e-25 89.4 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAP83488.1 - 6.8e-07 28.8 0.0 2.6e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP83488.1 - 0.00062 20.0 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAP83488.1 - 0.0089 15.3 1.3 2.2 7.5 0.3 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP83488.1 - 0.012 14.7 0.7 0.031 13.4 0.2 2.0 3 0 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.19 GAP83488.1 - 0.017 14.4 0.2 0.027 13.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAP83488.1 - 0.055 12.2 0.1 0.14 10.8 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 GAP83488.1 - 0.066 12.8 0.2 1 8.9 0.1 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAP83488.1 - 0.073 12.4 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 GAP83488.1 - 0.19 11.4 0.1 0.42 10.2 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_15 PF00723.21 GAP83489.1 - 1.6e-51 175.5 0.0 7.4e-46 156.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 F-box-like PF12937.7 GAP83490.1 - 4.5e-05 23.3 0.3 9.6e-05 22.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP83490.1 - 0.0049 16.7 0.3 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 F-box domain Bromo_TP PF07524.13 GAP83491.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAFII55_N PF04658.13 GAP83492.1 - 2e-42 144.6 0.0 5e-42 143.3 0.0 1.7 1 0 0 1 1 1 1 TAFII55 protein conserved region D123 PF07065.14 GAP83492.1 - 0.37 9.9 4.1 1.2 8.2 4.1 1.9 1 0 0 1 1 1 0 D123 CNDH2_C PF16858.5 GAP83492.1 - 0.45 10.3 13.0 1.4 8.7 0.6 2.5 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Ribosomal_L37 PF08561.10 GAP83493.1 - 4.7e-42 143.3 1.8 4.7e-42 143.3 1.8 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L37 Dicty_REP PF05086.12 GAP83493.1 - 0.29 9.0 1.6 0.32 8.9 1.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 GAP83493.1 - 4.1 7.4 25.9 5.5 7.0 24.7 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein MGC-24 PF05283.11 GAP83493.1 - 4.7 7.7 11.1 10 6.5 11.1 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pkinase PF00069.25 GAP83494.1 - 2.4e-07 30.4 0.0 4.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 GAP83494.1 - 1.6e-05 24.3 0.0 4.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP83494.1 - 0.0004 20.4 2.8 0.00079 19.4 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.6 GAP83494.1 - 0.0089 16.0 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.20 GAP83494.1 - 0.0095 15.5 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 GAP83494.1 - 0.024 13.7 0.1 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_Tyr PF07714.17 GAP83494.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase SVIP PF15811.5 GAP83494.1 - 0.22 12.0 10.3 0.98 9.9 10.3 2.1 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Macoilin PF09726.9 GAP83494.1 - 2.5 6.5 14.4 0.17 10.4 8.9 1.7 2 0 0 2 2 2 0 Macoilin family CDC45 PF02724.14 GAP83494.1 - 4.2 5.6 6.6 0.27 9.5 0.4 1.9 2 0 0 2 2 2 0 CDC45-like protein NDUFB10 PF10249.9 GAP83495.1 - 0.011 16.2 0.0 0.012 16.1 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 GAP83495.1 - 0.058 14.1 0.0 0.086 13.6 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase Ank_2 PF12796.7 GAP83496.1 - 4.2e-05 24.0 0.0 0.00015 22.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP83496.1 - 0.016 15.5 0.0 4.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP83496.1 - 0.099 13.3 0.0 5.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat AAA_16 PF13191.6 GAP83497.1 - 4.5e-05 23.9 0.0 9.9e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP83497.1 - 0.00078 19.7 0.1 0.0014 18.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 GAP83497.1 - 0.002 18.0 0.1 0.003 17.5 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NACHT PF05729.12 GAP83497.1 - 0.0028 17.6 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 GAP83497.1 - 0.0029 17.8 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAP83497.1 - 0.0061 17.0 0.0 0.0089 16.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAP83497.1 - 0.022 15.1 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 GAP83497.1 - 0.041 13.6 0.1 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 GAP83497.1 - 0.046 13.3 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 GAP83497.1 - 0.056 12.7 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 GAP83497.1 - 0.056 13.2 0.1 0.089 12.5 0.1 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 GAP83497.1 - 0.077 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF463 PF04317.12 GAP83497.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_17 PF13207.6 GAP83497.1 - 0.12 12.8 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Ploopntkinase1 PF18748.1 GAP83497.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 AAA_18 PF13238.6 GAP83497.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 GAP83498.1 - 6.2e-37 125.3 0.5 8.9e-18 63.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAP83498.1 - 0.0007 19.7 0.2 0.38 10.9 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Pkinase PF00069.25 GAP83500.1 - 2.1e-60 204.3 0.0 1.9e-38 132.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP83500.1 - 1.3e-27 96.8 0.0 5e-20 71.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 GAP83500.1 - 3.8e-14 52.8 0.0 7.2e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 GAP83500.1 - 1.6e-07 30.9 0.0 0.00011 21.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 GAP83500.1 - 4.2e-05 23.6 0.8 0.0035 17.3 0.1 3.2 3 1 1 4 4 4 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAP83500.1 - 0.0092 15.0 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAP83500.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAP83500.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_9 PF13426.7 GAP83500.1 - 0.15 12.4 0.0 0.59 10.4 0.0 2.0 2 0 0 2 2 2 0 PAS domain Pkinase_fungal PF17667.1 GAP83501.1 - 3e-08 32.9 0.0 3.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase bZIP_1 PF00170.21 GAP83502.1 - 1.2e-05 25.3 8.2 2.4e-05 24.4 8.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAP83502.1 - 0.69 10.0 10.7 4.2 7.5 10.7 2.1 1 1 0 1 1 1 0 Basic region leucine zipper eIF-3_zeta PF05091.12 GAP83503.1 - 4.7e-208 692.4 0.0 5.7e-208 692.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 GAP83503.1 - 0.0058 16.3 0.1 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF569) Ribul_P_3_epim PF00834.19 GAP83504.1 - 4e-62 209.1 0.0 2.2e-61 206.7 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Aminotran_5 PF00266.19 GAP83505.1 - 1.6e-40 139.3 0.0 1e-35 123.4 0.0 2.8 2 1 0 2 2 2 2 Aminotransferase class-V TilS PF09179.11 GAP83505.1 - 3.1 8.4 6.4 3 8.4 1.1 2.6 2 0 0 2 2 2 0 TilS substrate binding domain Fringe PF02434.16 GAP83506.1 - 5.4e-10 39.1 0.0 1.2e-07 31.5 0.1 3.0 2 1 0 2 2 2 1 Fringe-like Acetyltransf_6 PF13480.7 GAP83506.1 - 0.01 16.0 3.2 0.19 11.9 0.5 3.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain PAN_4 PF14295.6 GAP83506.1 - 0.03 14.2 1.5 0.062 13.2 1.5 1.6 1 0 0 1 1 1 0 PAN domain Glyco_transf_34 PF05637.12 GAP83506.1 - 0.33 10.7 1.3 0.54 9.9 1.3 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family IMUP PF15761.5 GAP83506.1 - 4.3 8.1 6.1 8 7.2 6.1 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Ofd1_CTDD PF10637.9 GAP83507.1 - 3e-94 315.2 0.0 4.8e-90 301.4 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 GAP83507.1 - 2.4e-25 89.0 0.0 9e-25 87.2 0.0 2.0 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 GAP83507.1 - 6.4e-13 49.4 0.1 1.9e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TFIIF_alpha PF05793.12 GAP83507.1 - 4.1 5.9 24.3 0.03 12.9 15.6 1.9 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Metallophos PF00149.28 GAP83508.1 - 4.8e-08 33.8 2.2 4.8e-08 33.8 2.2 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF3381 PF11861.8 GAP83508.1 - 0.6 9.9 12.8 0.18 11.6 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) His_Phos_1 PF00300.22 GAP83509.1 - 5.1e-13 49.2 0.0 6.2e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Stk19 PF10494.9 GAP83510.1 - 6.1e-37 127.6 0.0 8.1e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 LexA_DNA_bind PF01726.16 GAP83510.1 - 0.084 12.7 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 LexA DNA binding domain Kinesin PF00225.23 GAP83511.1 - 4.9e-96 321.5 0.0 7.8e-96 320.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAP83511.1 - 1.5e-21 76.9 0.0 3.5e-20 72.5 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 GAP83511.1 - 0.014 15.2 0.7 0.014 15.2 0.7 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ALC PF17527.2 GAP83511.1 - 0.15 11.7 0.4 0.32 10.6 0.4 1.5 1 0 0 1 1 1 0 Phage ALC protein Tho2 PF11262.8 GAP83511.1 - 2.5 7.2 4.1 4.8 6.3 4.1 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 p450 PF00067.22 GAP83513.1 - 1.8e-68 231.4 0.0 2.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Gcn1_N PF12074.8 GAP83513.1 - 0.017 14.4 0.2 0.037 13.3 0.2 1.5 1 1 0 1 1 1 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal DUF3045 PF11243.8 GAP83513.1 - 0.053 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) DUF3074 PF11274.8 GAP83514.1 - 5.6e-41 140.5 0.2 7.8e-41 140.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) CRT10 PF08728.10 GAP83515.1 - 9.3e-07 27.4 0.0 3.5e-06 25.5 0.0 1.9 2 1 0 2 2 2 1 CRT10 Ammonium_transp PF00909.21 GAP83516.1 - 1.4e-110 369.7 28.6 1.6e-110 369.5 28.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Fungal_trans PF04082.18 GAP83517.1 - 3.5e-28 98.4 0.0 4.2e-27 94.9 0.0 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP83517.1 - 2.8e-09 37.0 7.6 4.8e-09 36.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DcpS PF05652.12 GAP83518.1 - 4.7e-34 117.3 0.0 8.4e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 GAP83518.1 - 1.4e-28 99.7 0.7 2.8e-28 98.7 0.7 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Dynamitin PF04912.14 GAP83518.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Dynamitin Hexokinase_1 PF00349.21 GAP83519.1 - 7.4e-49 166.4 0.0 1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 GAP83519.1 - 7e-45 153.3 0.0 9.1e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase MFS_1 PF07690.16 GAP83520.1 - 3.8e-43 147.8 49.8 1.8e-42 145.6 45.9 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP83520.1 - 5.2e-14 52.0 10.7 3.9e-13 49.1 1.6 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 GAP83520.1 - 9.2e-07 27.7 6.4 9.2e-07 27.7 6.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 GAP83520.1 - 1.3 7.3 5.7 0.21 9.8 0.8 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Myb_Cef PF11831.8 GAP83521.1 - 2.8e-51 174.4 3.9 2.8e-51 174.4 3.9 3.3 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 GAP83521.1 - 3.8e-24 84.6 4.4 5.3e-12 45.7 0.6 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP83521.1 - 9.6e-22 77.0 7.1 7.1e-15 55.0 2.4 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 GAP83521.1 - 0.23 11.5 6.0 0.33 11.1 0.0 3.6 4 0 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Cyt-b5 PF00173.28 GAP83523.1 - 9.1e-13 48.2 0.0 1.2e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF5555 PF17710.1 GAP83523.1 - 0.15 11.5 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5555) MACPF PF01823.19 GAP83524.1 - 6.8e-08 32.9 0.1 1.6e-07 31.7 0.1 1.5 1 1 0 1 1 1 1 MAC/Perforin domain Glyco_transf_15 PF01793.16 GAP83525.1 - 1.7e-92 310.1 3.8 2.6e-92 309.6 3.8 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase KASH PF10541.9 GAP83525.1 - 2.7 8.3 5.5 5.4 7.4 5.5 1.5 1 0 0 1 1 1 0 Nuclear envelope localisation domain EXS PF03124.14 GAP83526.1 - 3.2e-111 371.8 7.3 3.7e-111 371.6 7.3 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.14 GAP83527.1 - 2.9e-42 144.8 0.3 3.9e-42 144.4 0.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 GAP83527.1 - 6.3e-12 45.1 8.4 1e-11 44.5 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP83527.1 - 2.7e-11 43.6 8.7 4.7e-11 42.8 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 GAP83527.1 - 3.3e-10 39.7 6.5 5.1e-10 39.1 6.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP83527.1 - 6.4e-10 38.7 6.4 1.1e-09 38.0 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP83527.1 - 1.5e-07 31.4 7.1 2.8e-07 30.4 7.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAP83527.1 - 3.1e-07 30.2 5.5 5.2e-07 29.5 5.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 GAP83527.1 - 7e-07 29.4 7.0 1.3e-06 28.5 7.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 GAP83527.1 - 7.6e-07 29.2 7.7 1.3e-06 28.5 7.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAP83527.1 - 9.2e-07 28.6 6.9 1.5e-06 27.9 6.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GAP83527.1 - 0.00057 20.0 5.9 0.00098 19.2 5.9 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 GAP83527.1 - 0.0007 19.4 2.2 0.0013 18.5 2.2 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 GAP83527.1 - 0.0041 16.9 0.8 0.0069 16.2 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 GAP83527.1 - 0.072 12.9 6.1 0.15 11.9 6.1 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Dicty_REP PF05086.12 GAP83527.1 - 0.13 10.2 5.4 0.18 9.8 5.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-ANAPC11 PF12861.7 GAP83527.1 - 0.24 11.5 4.3 0.65 10.1 4.3 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Shisa PF13908.6 GAP83527.1 - 0.35 11.1 2.9 0.77 10.0 2.9 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator zf-RING_11 PF17123.5 GAP83527.1 - 0.52 10.1 3.3 1.1 9.1 3.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 GAP83527.1 - 0.57 9.8 5.2 1 9.0 5.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FSA_C PF10479.9 GAP83527.1 - 0.91 7.6 2.6 5.9 4.9 4.3 1.4 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Mucin PF01456.17 GAP83527.1 - 1.1 9.2 22.0 2.2 8.3 22.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Aim21 PF11489.8 GAP83527.1 - 1.4 7.8 5.8 2.1 7.1 5.8 1.2 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 21 SSP160 PF06933.11 GAP83527.1 - 3.1 5.9 14.9 4.9 5.2 14.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-LYAR PF08790.11 GAP83528.1 - 5.1e-08 32.7 0.2 1e-07 31.7 0.2 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Hydrolase_4 PF12146.8 GAP83529.1 - 1.2e-17 64.0 0.0 1.4e-12 47.4 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP83529.1 - 7.4e-12 45.5 0.1 1.6e-08 34.5 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 GAP83529.1 - 1.8e-06 26.9 0.0 0.066 11.9 0.0 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 GAP83529.1 - 5.6e-05 23.8 0.0 0.00014 22.5 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAP83529.1 - 0.00011 21.8 0.0 0.00024 20.6 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 GAP83529.1 - 0.00019 21.1 0.0 0.0017 18.0 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 GAP83529.1 - 0.00028 20.6 0.0 0.00066 19.4 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DUF818 PF05677.12 GAP83529.1 - 0.00061 18.8 0.0 0.00095 18.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 GAP83529.1 - 0.024 14.4 0.1 0.95 9.2 0.1 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 GAP83529.1 - 0.031 14.2 0.0 0.92 9.4 0.0 2.2 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 GAP83529.1 - 0.032 14.1 0.0 0.083 12.7 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 GAP83529.1 - 0.077 12.6 0.0 7.1 6.1 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 GAP83529.1 - 0.1 12.3 0.5 1.5 8.5 0.4 2.4 1 1 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 GAP83529.1 - 0.16 11.5 0.0 0.44 10.1 0.0 1.6 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 GAP83529.1 - 0.17 11.7 0.0 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thioredoxin PF00085.20 GAP83531.1 - 1.6e-64 214.3 1.9 7.2e-32 109.5 0.2 3.9 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 GAP83531.1 - 1.1e-48 165.5 0.8 1.6e-36 125.9 0.1 3.7 2 2 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 GAP83531.1 - 4.1e-10 39.7 0.1 0.0013 18.9 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 GAP83531.1 - 1.4e-08 35.1 0.9 0.0008 19.8 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 GAP83531.1 - 1.5e-08 34.4 0.3 0.0038 16.6 0.0 2.7 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GAP83531.1 - 1.5e-08 34.8 0.0 0.0033 17.7 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.17 GAP83531.1 - 3.9e-08 32.7 0.6 3.9e-08 32.7 0.6 2.6 2 1 0 3 3 3 1 Calsequestrin AhpC-TSA PF00578.21 GAP83531.1 - 1.8e-06 27.9 1.8 0.015 15.2 0.1 3.1 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 GAP83531.1 - 2.1e-06 27.5 2.3 0.012 15.3 0.0 3.2 2 1 1 3 3 3 2 Redoxin ERp29_N PF07912.13 GAP83531.1 - 0.00026 21.1 0.4 3 8.0 0.0 3.9 3 2 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.6 GAP83531.1 - 0.0014 18.9 1.5 0.24 11.5 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin DSBA PF01323.20 GAP83531.1 - 0.0037 17.1 0.1 20 4.9 0.0 4.1 3 1 1 4 4 4 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 GAP83531.1 - 0.0067 16.5 0.1 0.048 13.7 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain IL33 PF15095.6 GAP83531.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Interleukin 33 Cas9_Topo PF17894.1 GAP83532.1 - 0.023 14.7 0.0 0.08 13.0 0.0 1.9 1 0 0 1 1 1 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 ATXN-1_C PF12547.8 GAP83532.1 - 1 9.8 4.9 4.2 7.8 2.0 3.3 1 1 1 2 2 2 0 Capicua transcriptional repressor modulator Mon1 PF03164.14 GAP83533.1 - 3e-153 510.7 0.0 3.5e-153 510.5 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 GCD14_N PF14801.6 GAP83533.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Dopey_N PF04118.14 GAP83534.1 - 1.7e-113 378.8 0.0 4.1e-112 374.3 0.0 2.5 2 0 0 2 2 2 2 Dopey, N-terminal bZIP_1 PF00170.21 GAP83535.1 - 0.00093 19.3 11.1 0.0016 18.5 11.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 GAP83535.1 - 0.048 13.4 6.2 0.12 12.2 6.2 1.6 1 1 0 1 1 1 0 Septum formation initiator Tmemb_cc2 PF10267.9 GAP83535.1 - 0.18 10.9 4.3 0.26 10.4 4.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Fib_alpha PF08702.10 GAP83535.1 - 0.28 11.4 2.2 1.1 9.4 3.0 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family THOC7 PF05615.13 GAP83535.1 - 0.62 10.4 8.9 1.1 9.5 8.9 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 bZIP_Maf PF03131.17 GAP83535.1 - 1 9.9 12.3 2.1 9.0 12.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Atg14 PF10186.9 GAP83535.1 - 3.5 6.6 7.9 5.5 6.0 7.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 GAP83535.1 - 3.7 4.9 13.7 4.9 4.5 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HET PF06985.11 GAP83536.1 - 0.00018 21.9 0.9 0.19 12.1 0.4 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) YwiC PF14256.6 GAP83536.1 - 0.051 13.9 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 YwiC-like protein FA_desaturase PF00487.24 GAP83536.1 - 0.11 12.3 1.0 0.22 11.3 1.0 1.4 1 0 0 1 1 1 0 Fatty acid desaturase RRN3 PF05327.11 GAP83537.1 - 9.6e-170 565.8 0.0 9.6e-170 565.8 0.0 2.3 3 0 0 3 3 3 1 RNA polymerase I specific transcription initiation factor RRN3 CBFD_NFYB_HMF PF00808.23 GAP83538.1 - 4.1e-29 100.6 1.0 5.5e-29 100.2 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAP83538.1 - 9.1e-06 26.1 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 GAP83538.1 - 0.0012 18.9 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 GAP83538.1 - 0.0019 18.1 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 GAP83538.1 - 0.0059 16.7 0.0 0.008 16.3 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 GAP83538.1 - 0.044 14.3 0.1 0.13 12.8 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.20 GAP83539.1 - 7.5e-27 93.4 9.8 8.5e-27 93.2 9.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4757 PF15949.5 GAP83539.1 - 0.00037 21.0 2.8 0.00047 20.7 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4757) TACC_C PF05010.14 GAP83539.1 - 0.0036 17.1 6.5 0.0044 16.8 6.5 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2205 PF10224.9 GAP83539.1 - 0.032 14.2 5.7 0.11 12.5 0.9 2.2 2 0 0 2 2 2 0 Short coiled-coil protein Prefoldin PF02996.17 GAP83539.1 - 0.032 14.1 6.7 3.8 7.4 6.8 2.3 1 1 0 1 1 1 0 Prefoldin subunit CagS PF16707.5 GAP83539.1 - 0.04 13.9 1.4 0.046 13.7 1.4 1.1 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Golgin_A5 PF09787.9 GAP83539.1 - 0.045 13.2 5.6 0.05 13.1 5.6 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 HBB PF06777.11 GAP83539.1 - 0.047 13.4 0.4 0.09 12.4 0.4 1.6 1 1 0 1 1 1 0 Helical and beta-bridge domain Tho2 PF11262.8 GAP83539.1 - 0.058 12.6 3.6 0.34 10.1 3.6 1.9 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Syntaxin-6_N PF09177.11 GAP83539.1 - 0.078 13.5 3.5 1.7 9.2 3.5 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal SAS-6_N PF16531.5 GAP83539.1 - 0.083 13.5 0.4 0.13 12.8 0.4 1.6 1 1 0 1 1 1 0 Centriolar protein SAS N-terminal SLATT_1 PF18181.1 GAP83539.1 - 0.089 12.7 1.0 0.22 11.4 0.3 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 OmpH PF03938.14 GAP83539.1 - 0.13 12.6 9.0 1.9 8.8 2.1 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2089 PF09862.9 GAP83539.1 - 0.52 10.4 3.7 3.2 7.8 3.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2089) Rho_Binding PF08912.11 GAP83539.1 - 0.99 10.3 10.9 0.74 10.7 2.3 2.3 2 0 0 2 2 2 0 Rho Binding Spc24 PF08286.11 GAP83539.1 - 1.3 9.3 8.2 0.45 10.8 2.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Tmemb_14 PF03647.13 GAP83540.1 - 1.1e-23 83.8 8.8 1.2e-23 83.6 8.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DAD PF02109.16 GAP83541.1 - 6e-51 171.3 1.5 7.1e-51 171.1 1.5 1.1 1 0 0 1 1 1 1 DAD family TrbL PF04610.14 GAP83541.1 - 0.0046 16.8 0.2 0.0064 16.3 0.1 1.4 1 1 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein GRASP55_65 PF04495.14 GAP83542.1 - 1.6e-44 151.5 0.0 1.9e-43 148.1 0.0 2.0 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 GAP83542.1 - 0.019 14.8 0.1 4.2 7.3 0.1 2.4 2 0 0 2 2 2 0 PDZ domain Methyltransf_15 PF09445.10 GAP83543.1 - 2.9e-41 140.8 0.0 3.7e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 GAP83543.1 - 3.8e-06 26.8 0.0 4.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein N6_Mtase PF02384.16 GAP83543.1 - 0.01 15.1 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_3 PF01596.17 GAP83543.1 - 0.027 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.18 GAP83543.1 - 0.045 13.4 0.0 0.075 12.7 0.0 1.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 DNA_methylase PF00145.17 GAP83543.1 - 0.062 12.6 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_18 PF12847.7 GAP83543.1 - 0.21 11.5 0.0 0.79 9.6 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain DSPc PF00782.20 GAP83544.1 - 7.9e-23 80.7 0.0 1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain HEAT_2 PF13646.6 GAP83545.1 - 3.1e-36 123.6 49.8 5.9e-07 29.8 3.8 6.9 2 2 9 11 11 11 11 HEAT repeats NACHT PF05729.12 GAP83545.1 - 6e-19 68.6 0.0 1.3e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Vac14_Fab1_bd PF12755.7 GAP83545.1 - 2.4e-15 56.9 15.3 0.037 14.6 0.1 10.9 2 2 9 11 11 11 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAP83545.1 - 1.4e-14 53.0 21.6 0.57 10.6 0.1 10.8 11 0 0 11 11 11 5 HEAT repeat HEAT_EZ PF13513.6 GAP83545.1 - 6.3e-14 52.1 29.4 1.4 9.5 0.4 11.6 8 2 4 12 12 12 6 HEAT-like repeat Cnd1 PF12717.7 GAP83545.1 - 3.2e-12 46.8 14.4 0.045 13.8 0.9 7.8 2 2 7 9 9 9 4 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 GAP83545.1 - 1.2e-08 35.1 6.1 12 6.0 0.0 9.2 6 3 2 9 9 9 0 V-ATPase subunit H Adaptin_N PF01602.20 GAP83545.1 - 4e-08 32.3 5.1 4.1e-05 22.3 0.1 4.5 2 2 0 3 3 3 1 Adaptin N terminal region NLRC4_HD2 PF17776.1 GAP83545.1 - 1.4e-06 28.9 0.1 2.3e-05 24.9 0.1 2.9 2 0 0 2 2 2 1 NLRC4 helical domain HD2 NB-ARC PF00931.22 GAP83545.1 - 4.2e-06 26.2 0.0 8.4e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Arm PF00514.23 GAP83545.1 - 1.3e-05 25.0 15.2 17 5.6 0.0 9.8 11 0 0 11 11 10 0 Armadillo/beta-catenin-like repeat AAA_22 PF13401.6 GAP83545.1 - 1.4e-05 25.4 0.6 0.00027 21.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain Nipped-B_C PF12830.7 GAP83545.1 - 4.3e-05 23.5 12.4 2.7 7.9 0.1 7.1 3 3 5 8 8 8 1 Sister chromatid cohesion C-terminus Sec6 PF06046.13 GAP83545.1 - 0.00057 18.4 0.1 0.73 8.1 0.0 3.0 1 1 2 3 3 3 2 Exocyst complex component Sec6 SEN1_N PF12726.7 GAP83545.1 - 0.0014 16.9 0.0 0.33 9.1 0.0 2.9 2 1 0 2 2 2 1 SEN1 N terminal AAA_18 PF13238.6 GAP83545.1 - 0.0032 18.0 0.1 0.027 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RICTOR_N PF14664.6 GAP83545.1 - 0.0038 16.3 0.2 6.2 5.7 0.0 4.6 2 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 GAP83545.1 - 0.0091 16.4 18.5 17 5.8 0.0 7.8 3 3 5 9 9 9 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain AAA PF00004.29 GAP83545.1 - 0.0093 16.4 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF5578 PF17741.1 GAP83545.1 - 0.021 14.3 0.6 6 6.2 0.0 3.2 1 1 2 3 3 3 0 Family of unknown function (DUF5578) NTPase_1 PF03266.15 GAP83545.1 - 0.038 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase RTP1_C1 PF10363.9 GAP83545.1 - 0.047 13.9 6.0 8.1 6.7 0.1 5.5 4 1 2 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 PduV-EutP PF10662.9 GAP83545.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Cohesin_HEAT PF12765.7 GAP83545.1 - 2.5 8.5 11.1 59 4.1 0.1 5.9 6 1 1 7 7 6 0 HEAT repeat associated with sister chromatid cohesion AAA_16 PF13191.6 GAP83545.1 - 3.1 8.1 7.9 0.42 11.0 0.2 3.2 2 2 0 2 2 2 0 AAA ATPase domain WSC PF01822.19 GAP83546.1 - 4.2e-52 174.3 44.1 2.8e-18 65.9 8.0 3.3 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.11 GAP83546.1 - 2.8e-26 92.2 0.0 8e-26 90.7 0.0 1.7 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 GAP83546.1 - 4.2e-20 71.8 0.0 8e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) 5TM-5TMR_LYT PF07694.12 GAP83546.1 - 0.22 11.0 2.5 0.41 10.1 2.5 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT R3H PF01424.22 GAP83547.1 - 1.8e-14 53.4 0.2 3.9e-14 52.4 0.2 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 GAP83547.1 - 6.8e-05 22.8 12.3 6.8e-05 22.8 12.3 8.1 8 2 0 8 8 8 2 NF-X1 type zinc finger zf-HIT PF04438.16 GAP83548.1 - 6.7e-08 32.3 4.4 9.9e-08 31.7 4.4 1.3 1 0 0 1 1 1 1 HIT zinc finger NolX PF05819.11 GAP83550.1 - 0.15 11.3 0.4 0.68 9.2 0.0 1.9 2 0 0 2 2 2 0 NolX protein Lactonase PF10282.9 GAP83551.1 - 0.00023 20.5 0.0 0.0048 16.2 0.0 2.6 1 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller bZIP_1 PF00170.21 GAP83552.1 - 0.0003 20.8 0.3 0.0003 20.8 0.3 1.7 2 0 0 2 2 2 1 bZIP transcription factor Ntox30 PF15532.6 GAP83552.1 - 0.0083 16.5 0.6 0.023 15.1 0.1 1.8 2 0 0 2 2 2 1 Bacterial toxin 30 WLM PF08325.10 GAP83553.1 - 5.2e-26 91.9 1.4 1.2e-25 90.7 1.4 1.7 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 GAP83553.1 - 9.6e-08 32.3 0.3 9.6e-08 32.3 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 DZR PF12773.7 GAP83553.1 - 0.16 12.0 3.9 0.85 9.7 4.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 GAP83553.1 - 1.9 7.9 7.4 0.088 12.2 1.2 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF4110 PF13422.6 GAP83554.1 - 1.7e-31 108.1 0.2 1.7e-31 108.1 0.2 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 GAP83554.1 - 1.1e-20 73.4 13.6 1.6e-07 31.4 0.0 6.6 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.6 GAP83554.1 - 3.7e-19 68.5 14.7 0.00011 22.2 0.5 6.6 4 2 2 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 GAP83554.1 - 1.7e-18 66.2 1.0 8e-07 28.9 0.1 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 GAP83554.1 - 2.3e-13 49.5 6.0 0.0018 18.2 0.0 6.2 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 GAP83554.1 - 1.1e-11 44.6 4.1 0.00063 19.9 0.2 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 GAP83554.1 - 2.2e-08 33.5 0.2 0.0026 17.3 0.0 5.0 5 0 0 5 5 5 1 Kelch motif YL1 PF05764.13 GAP83554.1 - 0.0086 16.2 13.2 0.0086 16.2 13.2 3.0 3 0 0 3 3 3 1 YL1 nuclear protein BUD22 PF09073.10 GAP83554.1 - 1.3 8.3 33.0 0.07 12.5 15.9 2.4 2 0 0 2 2 2 0 BUD22 Mito_carr PF00153.27 GAP83555.1 - 6.1e-63 208.8 0.3 5.4e-22 77.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.15 GAP83556.1 - 6.9e-46 155.7 3.4 8.1e-46 155.4 3.4 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF3546 PF12066.8 GAP83557.1 - 6.3e-34 116.5 2.0 6.3e-34 116.5 2.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 GAP83557.1 - 4.7e-12 45.5 0.1 1.2e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 GAP83557.1 - 1.3e-09 38.8 6.9 4.9e-09 36.8 6.9 2.1 1 1 0 1 1 1 1 Arsenite-resistance protein 2 PEP-utilisers_N PF05524.13 GAP83557.1 - 1.4 9.1 5.3 0.75 10.0 1.7 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Ribonuc_L-PSP PF01042.21 GAP83558.1 - 3e-23 82.1 0.0 4.1e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP TraH PF06122.11 GAP83558.1 - 0.11 11.7 1.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Conjugative relaxosome accessory transposon protein Alpha_E1_glycop PF01589.16 GAP83558.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein Sulf_transp PF04143.14 GAP83559.1 - 3.3e-33 115.6 27.6 6.5e-33 114.6 27.6 1.5 1 1 0 1 1 1 1 Sulphur transport ADH_zinc_N PF00107.26 GAP83560.1 - 1.8e-19 70.0 0.1 2.9e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP83560.1 - 1.7e-10 42.1 0.0 3.9e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP83560.1 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 GAP83560.1 - 0.01 15.3 0.1 0.017 14.6 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase SMK-1 PF04802.15 GAP83561.1 - 6.6e-79 264.2 5.1 6.8e-79 264.2 0.9 2.8 3 1 0 3 3 3 1 Component of IIS longevity pathway SMK-1 NblA PF04485.12 GAP83561.1 - 0.14 12.6 2.0 4.4 7.8 0.0 3.2 3 0 0 3 3 3 0 Phycobilisome degradation protein nblA Kelch_4 PF13418.6 GAP83563.1 - 0.00026 21.0 0.3 0.22 11.6 0.0 2.8 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAP83563.1 - 0.00061 20.0 1.4 0.2 12.0 0.0 3.1 3 1 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 GAP83563.1 - 0.0086 16.0 0.2 5.3 7.1 0.1 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 GAP83563.1 - 0.012 15.6 0.1 0.58 10.2 0.1 2.6 2 0 0 2 2 2 0 Kelch motif F5_F8_type_C PF00754.25 GAP83563.1 - 0.016 15.4 0.2 0.027 14.6 0.2 1.4 1 0 0 1 1 1 0 F5/8 type C domain Glyoxal_oxid_N PF07250.11 GAP83563.1 - 0.038 13.2 0.0 0.11 11.7 0.0 1.7 1 1 1 2 2 2 0 Glyoxal oxidase N-terminus MFS_1 PF07690.16 GAP83564.1 - 4.4e-25 88.4 75.6 5.8e-24 84.7 47.8 3.0 1 1 1 3 3 3 3 Major Facilitator Superfamily ABC2_membrane_3 PF12698.7 GAP83564.1 - 0.45 9.6 13.9 1.2 8.1 13.9 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein Caps_synth PF05704.12 GAP83566.1 - 2e-16 60.2 0.0 3.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 GAP83566.1 - 8.2e-05 23.2 0.0 0.00025 21.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Glyco_hydro_129 PF11308.8 GAP83566.1 - 0.002 17.3 0.0 0.0074 15.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases related to GH101 family, GH129 CDC45 PF02724.14 GAP83567.1 - 0.0018 16.7 6.3 0.0027 16.1 6.3 1.2 1 0 0 1 1 1 1 CDC45-like protein DDHD PF02862.17 GAP83567.1 - 0.0023 18.1 1.2 0.0061 16.7 1.2 1.7 1 0 0 1 1 1 1 DDHD domain DUF262 PF03235.14 GAP83567.1 - 0.0083 16.3 2.3 0.02 15.1 2.3 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF262 Vfa1 PF08432.10 GAP83567.1 - 0.011 16.1 28.5 0.023 15.0 28.5 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.11 GAP83567.1 - 0.027 13.0 5.3 0.05 12.2 5.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.15 GAP83567.1 - 0.059 12.1 5.5 0.089 11.6 5.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 GAP83567.1 - 0.13 12.3 3.9 0.23 11.5 3.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.12 GAP83567.1 - 0.21 10.9 24.6 0.43 9.9 24.6 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger RNA_pol_Rpc4 PF05132.14 GAP83567.1 - 0.25 11.8 14.4 0.55 10.7 14.4 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 GAP83567.1 - 0.25 10.5 7.2 0.51 9.5 7.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 GAP83567.1 - 0.3 10.5 16.7 0.53 9.7 16.7 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TERB2 PF15101.6 GAP83567.1 - 0.32 11.0 8.0 0.77 9.8 8.0 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NPR3 PF03666.13 GAP83567.1 - 0.35 9.6 17.2 0.59 8.9 17.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.8 GAP83567.1 - 1 8.2 26.9 1.9 7.3 26.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF913 PF06025.12 GAP83567.1 - 1 8.2 6.7 2.7 6.9 6.7 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BORG_CEP PF14957.6 GAP83567.1 - 1.3 10.2 9.6 0.81 10.9 7.4 1.8 2 0 0 2 2 1 0 Cdc42 effector Pox_Ag35 PF03286.14 GAP83567.1 - 2.3 8.0 23.6 5.6 6.7 23.6 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 GAP83567.1 - 4.7 6.6 19.7 8.4 5.7 19.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SLC12 PF03522.15 GAP83567.1 - 5 6.0 15.0 8.1 5.3 15.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Tim54 PF11711.8 GAP83567.1 - 5.3 5.7 20.5 8.8 5.0 20.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CENP-N PF05238.13 GAP83567.1 - 5.5 6.2 13.9 9.1 5.5 13.9 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DDRGK PF09756.9 GAP83567.1 - 6.8 6.2 41.3 13 5.3 41.3 1.4 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.12 GAP83567.1 - 8.5 6.1 28.1 16 5.2 28.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GCD14 PF08704.10 GAP83567.1 - 8.5 6.0 7.6 16 5.1 7.6 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Selenoprotein_S PF06936.11 GAP83567.1 - 9.2 6.0 20.3 17 5.1 20.3 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) Eapp_C PF10238.9 GAP83567.1 - 9.4 6.3 15.1 24 5.0 15.1 1.7 1 0 0 1 1 1 0 E2F-associated phosphoprotein Glycos_transf_2 PF00535.26 GAP83568.1 - 2.2e-23 82.9 0.0 7.1e-23 81.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 GAP83568.1 - 1.4e-07 31.6 0.1 5.2e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 GAP83568.1 - 0.02 15.4 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 GAP83568.1 - 0.029 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pribosyltran PF00156.27 GAP83568.1 - 0.093 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain SE PF08491.10 GAP83569.1 - 5.2e-83 278.3 0.0 6.6e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 GAP83569.1 - 2.5e-10 40.1 0.1 5.1e-07 29.3 0.0 2.2 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAP83569.1 - 1.2e-07 31.6 0.0 2.7e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP83569.1 - 0.00057 20.1 0.1 0.0015 18.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAP83569.1 - 0.00087 18.6 0.0 0.0021 17.3 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 GAP83569.1 - 0.0012 19.4 0.2 0.0041 17.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP83569.1 - 0.0012 18.1 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 GAP83569.1 - 0.002 18.2 0.1 0.0034 17.4 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.7 GAP83569.1 - 0.002 17.5 0.2 0.0093 15.4 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP83569.1 - 0.0024 17.0 1.9 0.004 16.3 1.0 1.7 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 GAP83569.1 - 0.0035 16.5 0.0 0.017 14.2 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 GAP83569.1 - 0.0037 17.3 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 GAP83569.1 - 0.0044 16.9 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 GAP83569.1 - 0.0057 16.3 0.1 0.0095 15.6 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 GAP83569.1 - 0.0067 15.5 0.2 0.018 14.1 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 GAP83569.1 - 0.069 11.8 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 GAP83569.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 GAP83569.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 ThiF family MerC PF03203.14 GAP83569.1 - 0.63 10.5 3.8 1.4 9.4 3.1 1.9 1 1 1 2 2 2 0 MerC mercury resistance protein Trypan_PARP PF05887.11 GAP83570.1 - 0.013 15.5 5.8 0.031 14.3 5.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mito_fiss_reg PF05308.11 GAP83570.1 - 5.7 7.0 6.4 10 6.1 6.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Mito_carr PF00153.27 GAP83571.1 - 1.4e-64 214.1 0.4 1.1e-21 76.6 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Pec_lyase PF09492.10 GAP83571.1 - 0.17 11.1 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Pectic acid lyase Peptidase_S24 PF00717.23 GAP83572.1 - 1.4e-05 24.9 0.2 4.7e-05 23.3 0.0 2.0 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 GAP83572.1 - 0.00046 20.0 0.0 0.048 13.4 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Amidase_6 PF12671.7 GAP83572.1 - 0.16 12.1 0.0 2.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Putative amidase domain EIF_2_alpha PF07541.12 GAP83573.1 - 8.7e-37 125.8 0.0 1.5e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 GAP83573.1 - 8.7e-14 51.6 0.7 1.5e-13 50.8 0.7 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Treacle PF03546.14 GAP83573.1 - 0.042 12.7 0.1 0.053 12.4 0.1 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle cNMP_binding PF00027.29 GAP83574.1 - 1e-28 99.2 0.3 2.5e-14 53.1 0.0 5.7 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 GAP83574.1 - 7.5e-17 62.2 3.1 4.5e-16 59.6 3.1 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase TMEM43 PF07787.12 GAP83574.1 - 6.3 6.1 8.5 42 3.4 9.3 1.8 2 0 0 2 2 2 0 Transmembrane protein 43 UPF0542 PF15086.6 GAP83575.1 - 0.89 9.5 6.0 0.14 12.1 1.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0542 Pyridoxal_deC PF00282.19 GAP83576.1 - 3.2e-104 348.6 0.0 3.9e-104 348.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain HNH_3 PF13392.6 GAP83577.1 - 0.0097 15.6 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF1272 PF06906.11 GAP83577.1 - 0.022 14.9 1.4 0.062 13.4 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 GAP83577.1 - 0.07 13.2 1.2 0.18 11.8 1.2 1.7 1 0 0 1 1 1 0 Double zinc ribbon Pax2_C PF12403.8 GAP83577.1 - 0.44 10.6 5.6 0.073 13.1 1.4 1.9 2 0 0 2 2 2 0 Paired-box protein 2 C terminal zinc-ribbons_6 PF07191.12 GAP83577.1 - 0.86 9.6 7.5 0.93 9.5 1.1 2.3 2 0 0 2 2 2 0 zinc-ribbons Glyco_hydro_61 PF03443.14 GAP83578.1 - 3.4e-19 69.6 0.0 6.1e-18 65.5 0.0 1.9 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 AAA_16 PF13191.6 GAP83579.1 - 9.1e-06 26.2 0.0 2.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 GAP83579.1 - 1.8e-05 24.7 0.0 4.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAP83579.1 - 0.00023 21.5 0.0 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 GAP83579.1 - 0.0045 16.9 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 NB-ARC PF00931.22 GAP83579.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF676 PF05057.14 GAP83579.1 - 0.016 14.7 0.0 0.078 12.5 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) MMR_HSR1 PF01926.23 GAP83579.1 - 0.07 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 GAP83579.1 - 0.077 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAP83579.1 - 0.088 13.3 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 GAP83579.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 GAP83579.1 - 0.18 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain KH_1 PF00013.29 GAP83580.1 - 1.9e-43 146.1 5.9 2.6e-18 65.6 0.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAP83580.1 - 1.8e-11 43.7 3.5 0.0032 17.3 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GAP83580.1 - 3.1e-06 27.0 0.5 0.38 10.6 0.1 3.2 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 GAP83580.1 - 0.00042 20.3 0.0 0.03 14.3 0.0 2.5 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 GAP83580.1 - 0.00074 19.6 9.3 0.39 10.8 0.4 3.4 3 0 0 3 3 3 3 NusA-like KH domain CENP-K PF11802.8 GAP83581.1 - 1.1e-06 28.4 4.6 0.034 13.7 0.0 2.6 2 1 0 2 2 2 2 Centromere-associated protein K BST2 PF16716.5 GAP83581.1 - 0.00079 20.0 3.5 0.00079 20.0 3.5 3.4 4 0 0 4 4 4 1 Bone marrow stromal antigen 2 DUF745 PF05335.13 GAP83581.1 - 0.025 14.3 4.9 0.48 10.1 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Unstab_antitox PF09720.10 GAP83581.1 - 0.53 10.4 2.8 1.3 9.1 0.1 3.0 3 0 0 3 3 3 0 Putative addiction module component DUF2514 PF10721.9 GAP83581.1 - 0.65 10.0 4.6 0.22 11.5 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) DUF948 PF06103.11 GAP83581.1 - 0.66 10.3 6.1 2.8 8.2 1.8 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Tropomyosin PF00261.20 GAP83581.1 - 0.73 9.2 11.2 0.35 10.2 5.6 2.4 2 0 0 2 2 2 0 Tropomyosin DUF848 PF05852.11 GAP83581.1 - 1.9 8.6 6.8 20 5.2 0.1 2.6 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SlyX PF04102.12 GAP83581.1 - 2.8 8.6 10.3 15 6.3 0.1 4.2 3 1 1 4 4 4 0 SlyX Syntaxin_2 PF14523.6 GAP83581.1 - 4 7.8 10.3 5.6 7.4 1.2 3.7 3 1 1 4 4 4 0 Syntaxin-like protein E2F_CC-MB PF16421.5 GAP83581.1 - 5.4 7.5 6.6 5.7 7.4 0.1 3.4 4 0 0 4 4 4 0 E2F transcription factor CC-MB domain BAR_3 PF16746.5 GAP83581.1 - 5.6 6.6 10.3 5.3 6.7 5.4 3.0 3 1 0 3 3 3 0 BAR domain of APPL family Cnn_1N PF07989.11 GAP83581.1 - 7.2 6.9 11.6 3.1 8.0 2.0 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 FAM76 PF16046.5 GAP83581.1 - 8 5.7 10.0 15 4.9 9.2 1.8 1 1 1 2 2 2 0 FAM76 protein dUTPase PF00692.19 GAP83582.1 - 4.5e-37 126.6 0.0 6.4e-37 126.1 0.0 1.2 1 0 0 1 1 1 1 dUTPase PCNA_N PF00705.18 GAP83583.1 - 7.7e-54 180.8 5.2 2.4e-53 179.2 4.1 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 GAP83583.1 - 2.1e-49 166.9 0.0 4.8e-49 165.8 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 GAP83583.1 - 2e-08 34.0 0.2 2.5e-08 33.7 0.2 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 GAP83583.1 - 7.9e-07 28.4 0.9 1.1e-05 24.7 0.9 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 GAP83583.1 - 0.0011 18.1 0.6 0.012 14.8 0.6 2.4 1 1 0 1 1 1 1 Hus1-like protein DNA_pol3_beta_3 PF02768.15 GAP83583.1 - 0.011 15.6 0.2 0.074 12.9 0.0 2.3 2 2 1 3 3 3 0 DNA polymerase III beta subunit, C-terminal domain Vezatin PF12632.7 GAP83584.1 - 5.2e-43 147.4 0.2 7.5e-43 146.9 0.2 1.2 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF747 PF05346.11 GAP83584.1 - 0.12 11.8 0.5 1.2 8.5 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic membrane protein family Rab5ip PF07019.12 GAP83585.1 - 8.2e-28 96.8 9.5 8.2e-28 96.8 9.5 1.8 2 0 0 2 2 2 1 Rab5-interacting protein (Rab5ip) Spo7 PF03907.13 GAP83585.1 - 0.045 13.2 1.0 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 Spo7-like protein GTP_EFTU PF00009.27 GAP83586.1 - 3.2e-08 33.3 0.0 1.6e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAP83586.1 - 0.009 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 GAP83586.1 - 0.15 12.3 0.1 3.7 7.8 0.2 2.7 3 0 0 3 3 3 0 AAA domain Dec-1 PF04624.14 GAP83587.1 - 0.094 12.6 2.7 0.75 9.7 1.4 3.0 2 0 0 2 2 2 0 Dec-1 repeat THOC7 PF05615.13 GAP83587.1 - 0.34 11.2 18.6 0.38 11.0 7.1 3.2 1 1 0 2 2 2 0 Tho complex subunit 7 WDCP PF15390.6 GAP83587.1 - 0.85 7.9 8.4 1.1 7.5 8.4 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family KxDL PF10241.9 GAP83587.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.7 3 1 1 4 4 4 0 Uncharacterized conserved protein Complex1_LYR_2 PF13233.6 GAP83588.1 - 7e-11 42.7 0.0 8.8e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAP83588.1 - 0.0015 18.5 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HA2 PF04408.23 GAP83589.1 - 3.8e-19 68.9 0.0 1e-18 67.6 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAP83589.1 - 7.2e-12 45.6 0.0 1.6e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GAP83589.1 - 5.9e-10 39.4 0.0 1.9e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 GAP83589.1 - 1.5e-06 28.1 0.0 4.1e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAP83589.1 - 0.00022 21.5 0.0 0.00067 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 GAP83589.1 - 0.024 14.4 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 GAP83589.1 - 0.11 11.6 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 GAP83589.1 - 0.17 12.4 0.0 0.5 10.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 GAP83589.1 - 0.19 11.1 0.0 0.48 9.7 0.0 1.6 1 0 0 1 1 1 0 KaiC MaoC_dehydratas PF01575.19 GAP83591.1 - 1.4e-22 79.6 0.0 2.3e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GAP83591.1 - 0.00026 21.1 0.0 0.52 10.5 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase CAP_GLY PF01302.25 GAP83592.1 - 8.5e-19 67.3 0.0 1.9e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 GAP83592.1 - 5.2e-13 49.0 3.6 0.022 15.2 0.0 5.0 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAP83592.1 - 5.7e-10 38.8 4.9 0.0065 16.2 0.3 4.7 4 2 1 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 GAP83592.1 - 1.6e-09 37.1 0.4 3.9 7.8 0.1 6.4 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 GAP83592.1 - 0.00029 21.0 1.1 68 4.6 0.0 6.0 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_9 PF14580.6 GAP83592.1 - 0.0013 18.3 0.0 0.12 11.8 0.0 3.0 1 1 0 2 2 2 1 Leucine-rich repeat Spem1 PF15670.5 GAP83593.1 - 0.52 9.9 2.5 0.97 9.0 2.5 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 zf_CCCH_4 PF18345.1 GAP83593.1 - 0.55 10.4 3.7 1.2 9.3 3.7 1.5 1 0 0 1 1 1 0 Zinc finger domain Phage_lysis PF03245.13 GAP83593.1 - 1.4 9.1 7.8 0.058 13.5 1.3 2.0 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein SAE2 PF08573.10 GAP83593.1 - 8.2 7.6 10.3 0.2 12.8 2.6 2.2 3 0 0 3 3 3 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Fer2_3 PF13085.6 GAP83594.1 - 1.3e-33 115.3 0.0 2e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 GAP83594.1 - 2.8e-08 34.2 5.5 2.8e-08 34.2 5.5 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAP83594.1 - 3.1e-07 30.7 7.4 3.1e-07 30.7 7.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAP83594.1 - 4.7e-07 29.8 3.0 4.7e-07 29.8 3.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 GAP83594.1 - 0.00096 19.7 3.5 0.00096 19.7 3.5 2.3 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 GAP83594.1 - 0.0018 18.2 0.3 0.0018 18.2 0.3 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DNA_pol3_tau_4 PF12168.8 GAP83594.1 - 0.2 12.2 0.4 0.2 12.2 0.4 1.7 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_9 PF13187.6 GAP83594.1 - 0.68 10.2 11.6 4.8 7.4 9.6 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain SpoIIE PF07228.12 GAP83595.1 - 1.2e-11 44.9 0.1 4.4e-11 43.1 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GAP83595.1 - 2.7e-09 37.1 0.0 0.0014 18.3 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAP83595.1 - 3.1e-08 33.5 0.3 7.5e-08 32.3 0.3 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C GPI-anchored PF10342.9 GAP83596.1 - 9.2e-15 55.2 0.2 9.2e-15 55.2 0.2 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MG2 PF01835.19 GAP83596.1 - 0.0057 17.1 0.5 0.016 15.6 0.5 2.1 1 1 0 1 1 1 1 MG2 domain Macoilin PF09726.9 GAP83596.1 - 0.03 12.9 12.0 0.031 12.8 12.0 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 GAP83596.1 - 0.18 11.0 24.0 0.2 10.8 24.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 GAP83596.1 - 0.49 10.0 6.9 0.55 9.8 6.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PPP4R2 PF09184.11 GAP83596.1 - 0.61 9.6 12.5 0.72 9.4 12.5 1.1 1 0 0 1 1 1 0 PPP4R2 GREB1 PF15782.5 GAP83596.1 - 1.7 5.6 10.8 1.8 5.6 10.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 GAP83596.1 - 3.1 7.6 15.6 3.4 7.5 15.6 1.1 1 0 0 1 1 1 0 SPX domain PRCC PF10253.9 GAP83596.1 - 7.3 7.3 17.8 11 6.8 17.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Plasmodium_Vir PF05795.11 GAP83596.1 - 8.8 5.6 9.6 11 5.3 9.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Methyltransf_16 PF10294.9 GAP83597.1 - 0.00074 19.3 0.0 0.027 14.2 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase MtrC PF04211.13 GAP83597.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C Methyltransf_31 PF13847.6 GAP83597.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.6 GAP83598.1 - 6.3e-06 26.3 0.0 2.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 GAP83598.1 - 6.4e-06 24.9 0.0 2.9e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAP83598.1 - 0.011 14.9 0.0 0.17 11.0 0.0 2.3 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Ank_2 PF12796.7 GAP83599.1 - 5.7e-149 485.1 0.1 1.9e-21 76.4 0.1 8.9 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.30 GAP83599.1 - 2.3e-95 309.2 0.0 1.7e-06 28.2 0.0 14.1 14 0 0 14 14 13 13 Ankyrin repeat Ank_3 PF13606.6 GAP83599.1 - 2.3e-91 288.6 0.0 8.3e-06 25.8 0.0 14.9 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.6 GAP83599.1 - 8.4e-88 287.7 4.7 2.9e-12 46.8 0.0 11.0 2 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP83599.1 - 5.5e-80 262.4 0.0 3.6e-08 33.5 0.0 12.4 2 1 12 14 14 14 13 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 GAP83599.1 - 2.1e-16 59.9 0.1 6.2e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 Phosphorylase superfamily NACHT PF05729.12 GAP83599.1 - 2.3e-05 24.4 0.0 0.0001 22.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain DUF4988 PF16378.5 GAP83599.1 - 6e-05 22.8 2.1 14 5.3 0.1 4.8 1 1 5 6 6 6 0 Domain of unknown function AAA_22 PF13401.6 GAP83599.1 - 0.00017 21.8 0.0 0.00043 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP83599.1 - 0.00029 21.3 0.0 0.0011 19.3 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain RNA_helicase PF00910.22 GAP83599.1 - 0.0028 18.0 0.0 0.007 16.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 GAP83599.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NUP PF06516.11 GAP83599.1 - 0.0081 15.4 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) ABC_tran PF00005.27 GAP83599.1 - 0.033 14.7 0.0 0.079 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 GAP83599.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GAP83599.1 - 0.12 11.7 0.0 0.45 9.8 0.0 1.8 1 1 1 2 2 2 0 KaiC KAP_NTPase PF07693.14 GAP83599.1 - 0.13 11.5 0.4 8.4 5.5 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 GAP83599.1 - 0.14 12.7 0.0 0.38 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cyt-b5 PF00173.28 GAP83600.1 - 1.1e-18 67.1 0.0 1.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FMN_dh PF01070.18 GAP83600.1 - 1.4e-17 63.8 5.1 1.6e-11 43.9 0.8 3.2 1 1 2 3 3 3 3 FMN-dependent dehydrogenase DUF3712 PF12505.8 GAP83601.1 - 1e-28 100.1 4.9 1e-28 100.1 4.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAP83601.1 - 0.00021 21.8 0.4 0.0035 17.9 0.1 2.6 2 1 0 2 2 2 1 Late embryogenesis abundant protein FolB PF02152.18 GAP83602.1 - 9.1e-19 68.0 0.0 1.5e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Dihydroneopterin aldolase Acetyltransf_1 PF00583.25 GAP83603.1 - 1.4e-08 35.0 0.0 2.6e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP83603.1 - 1.4e-05 25.4 0.0 1.9e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAP83603.1 - 2.9e-05 24.0 0.0 5.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP83603.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SET PF00856.28 GAP83604.1 - 2.7e-09 37.6 0.0 5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 SET domain AAA_13 PF13166.6 GAP83605.1 - 7.2e-05 21.6 12.5 0.00014 20.7 12.5 1.4 1 0 0 1 1 1 1 AAA domain Leu_zip PF15294.6 GAP83605.1 - 0.00018 21.2 12.7 0.0029 17.2 10.8 2.2 2 0 0 2 2 2 1 Leucine zipper DUF812 PF05667.11 GAP83605.1 - 0.00044 19.3 7.9 0.00044 19.3 7.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF812) NPV_P10 PF05531.12 GAP83605.1 - 0.0011 19.4 10.5 1.3 9.5 0.8 4.6 2 1 3 5 5 5 1 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 GAP83605.1 - 0.0045 17.0 21.2 0.17 11.9 6.6 3.4 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlqD PF11068.8 GAP83605.1 - 0.0067 16.8 11.0 1.3 9.4 0.6 3.3 1 1 1 2 2 2 1 YlqD protein ZapB PF06005.12 GAP83605.1 - 0.0076 16.7 0.3 0.0076 16.7 0.3 4.8 2 1 0 2 2 1 1 Cell division protein ZapB EzrA PF06160.12 GAP83605.1 - 0.01 14.1 14.2 0.26 9.4 2.6 2.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FlaC_arch PF05377.11 GAP83605.1 - 0.017 15.5 16.4 0.25 11.8 0.6 5.5 3 2 3 6 6 6 0 Flagella accessory protein C (FlaC) Metal_resist PF13801.6 GAP83605.1 - 0.018 15.2 0.9 0.018 15.2 0.9 2.6 2 0 0 2 2 2 0 Heavy-metal resistance Alpha-mann_mid PF09261.11 GAP83605.1 - 0.022 14.9 0.2 0.081 13.1 0.2 2.0 1 0 0 1 1 1 0 Alpha mannosidase middle domain Spc7 PF08317.11 GAP83605.1 - 0.029 13.2 21.1 0.15 10.9 1.7 2.8 1 1 1 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 GAP83605.1 - 0.03 13.7 12.9 0.018 14.4 7.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 GAP83605.1 - 0.072 13.1 13.5 0.28 11.2 0.5 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Filament PF00038.21 GAP83605.1 - 0.081 12.5 21.8 0.032 13.8 2.4 4.0 1 1 2 4 4 4 0 Intermediate filament protein Fez1 PF06818.15 GAP83605.1 - 0.09 13.2 20.1 0.041 14.3 12.0 3.0 1 1 1 2 2 2 0 Fez1 DIT1_PvcA PF05141.12 GAP83605.1 - 0.14 11.6 3.4 0.23 10.9 3.4 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein YabA PF06156.13 GAP83605.1 - 0.14 12.8 17.9 0.57 10.8 1.0 4.3 1 1 3 4 4 4 0 Initiation control protein YabA DUF4709 PF15821.5 GAP83605.1 - 0.19 12.0 8.8 0.042 14.1 3.6 2.5 2 1 2 4 4 2 0 Domain of unknown function (DUF4709) ADIP PF11559.8 GAP83605.1 - 0.26 11.4 23.4 0.87 9.7 0.6 4.1 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 GAP83605.1 - 0.27 11.4 18.5 0.69 10.1 6.1 3.6 1 1 3 4 4 4 0 Tropomyosin like IFT57 PF10498.9 GAP83605.1 - 0.34 9.8 13.6 0.21 10.5 7.9 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Viral_P18 PF04521.13 GAP83605.1 - 0.38 10.6 2.1 16 5.3 0.0 2.7 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein FAM184 PF15665.5 GAP83605.1 - 0.39 10.5 15.3 0.066 13.0 9.9 2.2 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B DUF724 PF05266.14 GAP83605.1 - 0.43 10.4 15.8 12 5.6 9.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF724) HIP1_clath_bdg PF16515.5 GAP83605.1 - 0.47 11.1 19.1 0.78 10.4 8.0 4.0 2 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF16 PF01519.16 GAP83605.1 - 0.6 10.6 12.1 0.14 12.7 1.7 3.4 1 1 2 3 3 3 0 Protein of unknown function DUF16 TPR_MLP1_2 PF07926.12 GAP83605.1 - 0.61 10.2 19.0 2.7 8.1 6.9 3.7 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CREPT PF16566.5 GAP83605.1 - 0.65 10.2 13.1 1.1 9.4 1.1 3.2 2 1 1 3 3 2 0 Cell-cycle alteration and expression-elevated protein in tumour LPP PF04728.13 GAP83605.1 - 0.69 10.3 10.3 1.4 9.4 0.0 4.6 3 1 2 5 5 5 0 Lipoprotein leucine-zipper DUF3450 PF11932.8 GAP83605.1 - 0.71 9.1 17.8 0.24 10.7 0.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Lipoprotein_7 PF01540.16 GAP83605.1 - 0.9 8.8 10.4 0.47 9.7 5.4 2.3 1 1 2 3 3 3 0 Adhesin lipoprotein Fib_alpha PF08702.10 GAP83605.1 - 0.91 9.7 17.8 0.48 10.6 3.0 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 GAP83605.1 - 1 7.2 8.8 3.4 5.5 0.3 1.9 1 1 1 2 2 2 0 Prominin DUF1090 PF06476.12 GAP83605.1 - 1.1 9.3 5.7 0.45 10.7 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1090) Exonuc_VII_S PF02609.16 GAP83605.1 - 1.3 9.2 5.8 16 5.7 0.2 2.6 2 0 0 2 2 2 0 Exonuclease VII small subunit Lectin_N PF03954.14 GAP83605.1 - 1.3 8.8 10.6 0.18 11.5 2.9 3.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain AAA_11 PF13086.6 GAP83605.1 - 1.3 8.8 12.1 0.18 11.5 8.0 1.6 2 0 0 2 2 1 0 AAA domain TolA_bind_tri PF16331.5 GAP83605.1 - 1.4 9.1 14.3 19 5.4 0.2 5.0 4 1 0 4 4 4 0 TolA binding protein trimerisation Csm1_N PF18504.1 GAP83605.1 - 1.7 9.0 18.0 7.2 7.0 0.2 5.2 2 1 3 5 5 5 0 Csm1 N-terminal domain DUF4200 PF13863.6 GAP83605.1 - 1.8 9.0 20.1 0.69 10.3 0.7 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF5082 PF16888.5 GAP83605.1 - 1.8 8.8 17.4 3.4 8.0 0.8 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) TMF_TATA_bd PF12325.8 GAP83605.1 - 2.3 8.5 19.2 22 5.3 3.9 3.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.11 GAP83605.1 - 2.5 8.2 13.1 0.43 10.7 1.9 3.4 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 CCDC-167 PF15188.6 GAP83605.1 - 2.6 8.4 17.6 0.97 9.8 1.3 4.6 4 1 0 4 4 4 0 Coiled-coil domain-containing protein 167 Spectrin PF00435.21 GAP83605.1 - 2.7 8.5 16.3 4 8.0 0.2 3.7 2 1 0 3 3 3 0 Spectrin repeat Baculo_PEP_C PF04513.12 GAP83605.1 - 3.5 7.7 14.8 9.5 6.3 2.1 3.4 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF745 PF05335.13 GAP83605.1 - 4 7.1 12.5 0.18 11.5 2.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF745) zf-C4H2 PF10146.9 GAP83605.1 - 4.8 7.4 17.4 6.7 7.0 11.4 2.7 1 1 1 2 2 2 0 Zinc finger-containing protein HrpB7 PF09486.10 GAP83605.1 - 4.8 7.5 14.9 0.53 10.7 1.0 3.8 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Exonuc_VII_L PF02601.15 GAP83605.1 - 5.4 6.5 17.2 1.8e+02 1.5 16.8 2.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 GAP83605.1 - 5.6 7.7 13.7 1.5 9.5 0.3 4.7 2 1 2 5 5 4 0 SlyX Atg14 PF10186.9 GAP83605.1 - 5.6 6.0 20.7 3.3 6.7 4.2 3.2 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin PF02996.17 GAP83605.1 - 8.8 6.3 13.6 24 4.9 0.2 4.4 3 2 1 4 4 4 0 Prefoldin subunit Snapin_Pallidin PF14712.6 GAP83605.1 - 9.3 6.7 16.9 1.4 9.4 3.3 4.2 3 1 1 4 4 3 0 Snapin/Pallidin RNase_T PF00929.24 GAP83606.1 - 5.5e-09 36.8 0.0 3.7e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Exonuclease TPR_1 PF00515.28 GAP83607.1 - 3.2e-22 77.4 2.0 5.9e-07 29.0 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAP83607.1 - 9e-21 72.3 4.8 3e-05 23.8 0.1 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAP83607.1 - 1.6e-17 62.9 3.9 3e-07 30.0 0.0 5.0 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 GAP83607.1 - 1.5e-12 47.9 5.3 0.00031 21.3 1.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP83607.1 - 4.2e-12 45.3 3.9 4e-05 23.5 0.1 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAP83607.1 - 1.2e-11 44.4 5.4 0.0081 16.9 0.1 5.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAP83607.1 - 1.8e-11 44.3 7.2 0.00016 22.1 2.6 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAP83607.1 - 6.1e-11 41.9 2.3 0.004 17.4 0.0 5.0 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAP83607.1 - 2e-10 40.7 0.9 0.0025 17.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP83607.1 - 4.4e-09 35.7 6.7 0.016 15.2 0.1 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAP83607.1 - 1.8e-08 34.5 8.9 4.7e-05 23.6 0.3 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAP83607.1 - 1.1e-06 28.8 3.7 0.69 10.7 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 GAP83607.1 - 8e-06 26.1 6.5 0.4 11.0 0.4 4.5 4 1 1 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP83607.1 - 1.1e-05 25.5 3.4 0.0095 16.1 0.7 2.6 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF4192 PF13830.6 GAP83607.1 - 0.0054 16.9 2.1 0.0079 16.3 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4192) MIT PF04212.18 GAP83607.1 - 0.023 14.8 0.7 11 6.2 0.0 3.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 GAP83607.1 - 0.025 14.6 0.0 7.5 6.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAP83607.1 - 0.05 13.5 9.2 0.14 12.1 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1641 PF07849.11 GAP83607.1 - 0.068 13.1 0.4 0.24 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) Retrotran_gag_2 PF14223.6 GAP83607.1 - 0.071 12.8 0.1 9.8 5.8 0.0 2.7 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type RRM_1 PF00076.22 GAP83608.1 - 1e-35 121.3 0.0 1.6e-17 63.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAP83608.1 - 0.00038 20.0 0.0 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAP83608.1 - 0.008 16.2 0.1 0.091 12.8 0.0 2.2 2 1 0 2 2 2 1 Limkain b1 RRM_Rrp7 PF17799.1 GAP83608.1 - 0.049 13.4 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 GAP83608.1 - 0.088 12.9 0.0 1.5 9.0 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 GAP83608.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HLH PF00010.26 GAP83609.1 - 6.9e-12 45.1 2.6 1.7e-11 43.9 1.5 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4776 PF16003.5 GAP83609.1 - 0.0016 17.5 1.2 0.0023 17.0 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4776) NRBF2 PF08961.10 GAP83609.1 - 0.0085 15.7 3.4 0.02 14.5 3.4 1.6 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 GAP83609.1 - 0.048 14.1 0.1 0.048 14.1 0.1 2.3 1 1 1 2 2 2 0 Cell division protein ZapB MSA-2c PF12238.8 GAP83609.1 - 0.082 12.9 0.1 0.082 12.9 0.1 2.5 3 0 0 3 3 3 0 Merozoite surface antigen 2c NifQ PF04891.12 GAP83609.1 - 0.38 11.1 3.1 0.77 10.1 3.1 1.5 1 0 0 1 1 1 0 NifQ DUF1213 PF06740.12 GAP83609.1 - 5.2 7.7 7.7 25 5.6 0.3 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) RepA_C PF04796.12 GAP83610.1 - 0.001 19.1 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid encoded RepA protein Zn_clus PF00172.18 GAP83611.1 - 1.5e-07 31.4 13.5 2.9e-07 30.5 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIN_8 PF18476.1 GAP83612.1 - 0.18 11.6 8.0 0.028 14.3 1.9 2.1 2 0 0 2 2 2 0 PIN like domain THOC7 PF05615.13 GAP83612.1 - 0.22 11.8 11.1 1.2 9.5 3.5 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 RST PF12174.8 GAP83612.1 - 0.9 9.5 2.9 11 6.0 0.1 3.2 2 1 1 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Mod_r PF07200.13 GAP83612.1 - 1 9.4 15.3 0.59 10.2 7.4 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PI3K_P85_iSH2 PF16454.5 GAP83612.1 - 1.5 8.4 12.7 0.61 9.7 0.7 3.1 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CLZ PF16526.5 GAP83612.1 - 2 8.8 11.0 1.8 8.9 0.9 3.4 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 GAP83612.1 - 4.8 6.0 13.4 1.2 8.0 6.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Fungal_trans PF04082.18 GAP83613.1 - 5.7e-25 87.8 0.0 9.6e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP83613.1 - 3.8e-07 30.1 12.6 6.4e-07 29.4 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.21 GAP83614.1 - 1.9e-17 63.4 0.0 3.7e-17 62.5 0.0 1.4 1 1 0 1 1 1 1 ThiF family PAPS_reduct PF01507.19 GAP83614.1 - 0.13 12.2 0.0 2.4 8.2 0.0 2.5 3 0 0 3 3 3 0 Phosphoadenosine phosphosulfate reductase family MFS_1 PF07690.16 GAP83616.1 - 1.1e-40 139.7 44.8 6e-39 134.0 45.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP83616.1 - 2.7e-15 56.2 10.5 2.7e-15 56.2 10.5 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAP83616.1 - 7.6e-05 21.3 20.4 0.00014 20.4 20.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 GAP83616.1 - 0.004 17.3 0.6 0.07 13.3 0.0 3.1 3 0 0 3 3 3 1 Poxvirus virion envelope protein A14 DUF2070 PF09843.9 GAP83616.1 - 0.4 8.9 11.7 0.24 9.6 4.5 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Anp1 PF03452.14 GAP83617.1 - 1.1e-113 379.0 0.5 2.7e-113 377.8 0.0 1.7 2 0 0 2 2 2 1 Anp1 Smg8_Smg9 PF10220.9 GAP83617.1 - 1 7.6 9.4 1.3 7.2 9.4 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Sec7 PF01369.20 GAP83618.1 - 6.1e-64 215.1 0.1 1e-63 214.4 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 GAP83618.1 - 2.3e-20 73.1 0.0 1.3e-17 64.2 0.0 4.0 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 GAP83618.1 - 0.028 14.1 1.0 0.058 13.0 0.1 1.9 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 SGL PF08450.12 GAP83619.1 - 0.00079 19.1 0.1 0.018 14.7 0.1 2.1 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region bZIP_1 PF00170.21 GAP83620.1 - 2e-08 34.2 10.1 2e-08 34.2 10.1 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAP83620.1 - 0.0003 20.8 9.5 0.0003 20.8 9.5 2.6 2 0 0 2 2 2 1 Basic region leucine zipper adh_short PF00106.25 GAP83623.1 - 9.4e-25 87.2 0.0 1.3e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP83623.1 - 2.6e-12 46.8 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAP83623.1 - 7.7e-07 28.8 0.0 0.00013 21.5 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAP83623.1 - 5.4e-06 26.4 0.0 1.2e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 GAP83623.1 - 0.0029 17.1 0.0 0.44 9.9 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAP83623.1 - 0.0081 16.1 0.0 0.064 13.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding S-layer PF07752.11 GAP83623.1 - 0.043 12.9 0.1 0.22 10.6 0.1 1.8 1 1 1 2 2 2 0 S-layer protein NmrA PF05368.13 GAP83623.1 - 0.069 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family FSIP2 PF15783.5 GAP83623.1 - 0.23 9.3 0.0 0.31 8.9 0.0 1.0 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 Fungal_trans_2 PF11951.8 GAP83624.1 - 1.1e-27 96.8 0.4 4.9e-26 91.4 0.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP83624.1 - 3.4e-08 33.5 6.4 5.8e-08 32.7 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_1 PF00300.22 GAP83625.1 - 0.16 11.7 0.0 0.54 9.9 0.0 1.9 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) Ribosomal_L44 PF00935.19 GAP83626.1 - 4.6e-36 123.1 10.9 6.5e-36 122.7 10.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 CIAPIN1 PF05093.13 GAP83627.1 - 2.1e-37 127.6 1.4 3.9e-37 126.8 1.4 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 GAP83627.1 - 2e-28 99.3 0.0 3.6e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus RdRP PF05183.12 GAP83628.1 - 3.3e-113 379.4 0.0 5.1e-113 378.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.6 GAP83628.1 - 1.8e-49 168.1 0.0 2.9e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAP83628.1 - 9.5e-42 143.6 0.8 2e-22 80.2 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 GAP83628.1 - 6.9e-14 52.4 0.1 3.3e-13 50.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAP83628.1 - 1.2e-12 48.0 0.1 3.9e-12 46.3 0.1 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 GAP83628.1 - 1.2e-07 31.9 0.0 1.3e-06 28.5 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 GAP83628.1 - 2.6e-06 27.4 0.1 0.0043 16.8 0.0 3.3 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 GAP83628.1 - 0.00013 21.5 0.1 0.00048 19.6 0.1 1.9 1 1 0 1 1 1 1 PhoH-like protein Helicase_RecD PF05127.14 GAP83628.1 - 0.00018 21.4 0.0 0.00062 19.7 0.0 1.9 1 1 0 1 1 1 1 Helicase DEAD PF00270.29 GAP83628.1 - 0.00024 20.9 0.0 0.00083 19.2 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 GAP83628.1 - 0.0018 17.8 0.1 0.0058 16.2 0.1 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.14 GAP83628.1 - 0.0031 17.5 0.3 1.2 9.1 0.2 2.7 1 1 1 2 2 2 1 Flavivirus DEAD domain UvrD_C_2 PF13538.6 GAP83628.1 - 0.0073 16.1 0.0 0.024 14.5 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 GAP83628.1 - 0.05 14.0 0.2 0.18 12.3 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAP83629.1 - 2.2e-30 106.1 0.2 2.9e-30 105.6 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP83629.1 - 2.6e-05 24.7 1.2 5.7e-05 23.6 1.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAP83629.1 - 0.00042 20.4 0.0 0.0024 17.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAP83629.1 - 0.0012 18.9 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_22 PF13401.6 GAP83629.1 - 0.0025 18.1 0.0 0.0073 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 GAP83629.1 - 0.005 16.5 0.0 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 Thymidylate kinase AAA_19 PF13245.6 GAP83629.1 - 0.0054 17.1 0.2 0.01 16.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain DUF2742 PF10888.8 GAP83629.1 - 0.016 15.5 1.0 0.036 14.3 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2742) AAA_32 PF13654.6 GAP83629.1 - 0.022 13.6 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAP83629.1 - 0.024 13.7 0.1 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 GAP83629.1 - 0.04 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 GAP83629.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Septin PF00735.18 GAP83629.1 - 0.092 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin MobB PF03205.14 GAP83629.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 GAP83629.1 - 0.16 12.1 0.9 1.2 9.3 0.7 2.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAP83629.1 - 0.21 12.0 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RHD3 PF05879.12 GAP83629.1 - 0.21 9.7 0.0 0.28 9.3 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) NAD_binding_9 PF13454.6 GAP83631.1 - 2.7e-11 43.7 0.0 1.3e-09 38.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAP83631.1 - 1.5e-05 24.3 0.4 4.5e-05 22.8 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP83631.1 - 0.027 13.7 0.0 4.6 6.4 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP83631.1 - 0.054 12.6 0.0 0.34 10.0 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Haem_oxygenas_2 PF14518.6 GAP83632.1 - 0.036 13.8 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Iron-containing redox enzyme Frag1 PF10277.9 GAP83633.1 - 2.1e-11 43.8 3.5 2.7e-11 43.4 3.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Pox_A14 PF05767.12 GAP83633.1 - 0.023 14.9 1.1 0.039 14.1 0.4 1.8 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 Sugar_tr PF00083.24 GAP83634.1 - 6.8e-68 229.6 20.0 2e-66 224.7 20.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP83634.1 - 1.6e-15 56.9 32.5 4.5e-15 55.4 23.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily BLOC1_2 PF10046.9 GAP83635.1 - 3.3e-06 27.3 0.2 0.00037 20.7 0.1 2.6 2 1 1 3 3 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 GAP83635.1 - 5.8e-06 26.4 2.0 0.00014 22.0 0.4 2.6 2 1 1 3 3 2 1 Haemolysin XhlA Baculo_PEP_C PF04513.12 GAP83635.1 - 1.1e-05 25.5 0.3 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 GAP83635.1 - 4.6e-05 23.8 0.8 0.00087 19.7 0.1 2.8 1 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.8 GAP83635.1 - 9.4e-05 22.3 0.1 0.002 18.1 0.0 2.1 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 GAP83635.1 - 9.6e-05 22.4 0.1 0.00073 19.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) CLZ PF16526.5 GAP83635.1 - 0.00038 20.8 1.2 0.22 11.9 0.2 3.0 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5082 PF16888.5 GAP83635.1 - 0.00043 20.5 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) Tropomyosin_1 PF12718.7 GAP83635.1 - 0.0011 19.1 0.2 0.0099 16.0 0.0 2.1 2 1 0 2 2 1 1 Tropomyosin like PspA_IM30 PF04012.12 GAP83635.1 - 0.0012 18.4 0.6 0.0027 17.3 0.2 1.8 2 1 0 2 2 2 1 PspA/IM30 family ZapB PF06005.12 GAP83635.1 - 0.0014 19.0 0.9 0.01 16.2 0.4 2.5 2 1 0 2 2 2 1 Cell division protein ZapB DUF16 PF01519.16 GAP83635.1 - 0.0017 18.8 1.0 0.0037 17.7 0.2 1.9 2 1 0 2 2 1 1 Protein of unknown function DUF16 MbeB_N PF04837.12 GAP83635.1 - 0.0025 18.1 0.1 0.0078 16.5 0.0 1.9 2 0 0 2 2 1 1 MbeB-like, N-term conserved region MbeD_MobD PF04899.12 GAP83635.1 - 0.0027 17.8 1.4 0.16 12.1 0.2 3.0 2 1 1 3 3 3 1 MbeD/MobD like FlaC_arch PF05377.11 GAP83635.1 - 0.0028 18.0 0.1 0.067 13.6 0.0 2.6 2 1 1 3 3 2 1 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 GAP83635.1 - 0.0032 17.5 0.1 0.01 15.9 0.0 1.7 2 0 0 2 2 2 1 Laminin Domain II SlyX PF04102.12 GAP83635.1 - 0.0044 17.6 0.7 0.0083 16.7 0.2 1.8 2 0 0 2 2 1 1 SlyX CENP-F_leu_zip PF10473.9 GAP83635.1 - 0.0063 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.6 GAP83635.1 - 0.0069 16.6 0.7 0.15 12.4 0.2 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4164) TRAF_BIRC3_bd PF16673.5 GAP83635.1 - 0.0083 15.9 0.1 0.17 11.7 0.1 3.0 1 1 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain bZIP_2 PF07716.15 GAP83635.1 - 0.0094 16.0 0.3 2.3 8.4 0.1 2.7 1 1 1 2 2 2 1 Basic region leucine zipper DUF4988 PF16378.5 GAP83635.1 - 0.0097 15.6 0.0 2.6 7.7 0.1 2.4 1 1 1 2 2 2 1 Domain of unknown function AAA_13 PF13166.6 GAP83635.1 - 0.012 14.3 0.0 0.018 13.7 0.0 1.2 1 1 0 1 1 1 0 AAA domain DUF948 PF06103.11 GAP83635.1 - 0.014 15.6 0.1 0.35 11.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ABC_tran_CTD PF16326.5 GAP83635.1 - 0.026 14.8 0.0 2.2 8.6 0.0 2.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain HrpB7 PF09486.10 GAP83635.1 - 0.028 14.8 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4795 PF16043.5 GAP83635.1 - 0.028 14.0 0.0 0.065 12.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF2730 PF10805.8 GAP83635.1 - 0.034 14.2 0.1 0.081 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Troponin PF00992.20 GAP83635.1 - 0.038 14.3 0.0 0.068 13.5 0.0 1.4 1 0 0 1 1 1 0 Troponin CENP-Q PF13094.6 GAP83635.1 - 0.042 14.0 0.4 0.067 13.4 0.4 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3552 PF12072.8 GAP83635.1 - 0.045 13.2 0.5 0.28 10.6 0.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) TelA PF05816.11 GAP83635.1 - 0.048 12.7 0.3 0.082 12.0 0.0 1.4 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) ADIP PF11559.8 GAP83635.1 - 0.05 13.7 0.2 0.087 12.9 0.0 1.5 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 GAP83635.1 - 0.066 13.3 0.1 1.9 8.7 0.0 2.4 1 1 1 2 2 2 0 bZIP transcription factor DivIVA PF05103.13 GAP83635.1 - 0.07 13.2 0.0 3.3 7.8 0.0 2.2 2 0 0 2 2 2 0 DivIVA protein Gp58 PF07902.11 GAP83635.1 - 0.075 11.3 0.3 0.11 10.8 0.1 1.3 2 0 0 2 2 2 0 gp58-like protein Fzo_mitofusin PF04799.13 GAP83635.1 - 0.076 12.6 0.1 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 fzo-like conserved region Apolipoprotein PF01442.18 GAP83635.1 - 0.08 12.8 2.4 0.92 9.4 2.4 2.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Dynactin_p22 PF07426.11 GAP83635.1 - 0.082 12.8 1.6 20 5.0 0.2 3.0 1 1 2 3 3 3 0 Dynactin subunit p22 TAN PF11640.8 GAP83635.1 - 0.091 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DUF5446 PF17522.2 GAP83635.1 - 0.091 12.9 0.3 7.7 6.8 0.2 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5446) BRI3BP PF14965.6 GAP83635.1 - 0.1 12.1 0.6 6 6.3 0.6 2.5 1 1 0 1 1 1 0 Negative regulator of p53/TP53 Phage_GP20 PF06810.11 GAP83635.1 - 0.11 12.2 0.1 0.24 11.2 0.0 1.6 2 0 0 2 2 1 0 Phage minor structural protein GP20 Fib_alpha PF08702.10 GAP83635.1 - 0.12 12.6 0.1 0.35 11.1 0.0 1.8 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family Tropomyosin PF00261.20 GAP83635.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Tropomyosin DUF3294 PF07957.11 GAP83635.1 - 0.12 12.1 0.8 1.1 9.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3294) UPF0449 PF15136.6 GAP83635.1 - 0.13 12.7 1.0 0.52 10.8 0.1 1.9 2 1 1 3 3 2 0 Uncharacterised protein family UPF0449 Osmo_CC PF08946.10 GAP83635.1 - 0.15 12.4 0.6 8.9 6.7 0.1 3.0 2 1 1 3 3 2 0 Osmosensory transporter coiled coil COG6 PF06419.11 GAP83635.1 - 0.15 10.3 0.0 0.47 8.6 0.0 1.7 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 Trimer_CC PF08954.11 GAP83635.1 - 0.2 11.2 3.1 0.91 9.1 1.7 2.5 1 1 1 2 2 2 0 Trimerisation motif Phage_holin_3_6 PF07332.11 GAP83636.1 - 0.027 14.5 0.1 0.027 14.5 0.1 2.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Amidase PF01425.21 GAP83637.1 - 3.7e-62 210.8 0.0 9.3e-62 209.4 0.0 1.5 1 1 0 1 1 1 1 Amidase Phage_glycop_gL PF11108.8 GAP83639.1 - 0.033 14.2 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 Viral glycoprotein L Glyco_tranf_2_2 PF10111.9 GAP83640.1 - 0.049 13.1 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DOCK_N PF16172.5 GAP83641.1 - 1.4e-80 271.1 0.7 2.4e-77 260.4 0.0 3.7 2 1 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 GAP83641.1 - 9e-36 123.6 3.6 2.7e-35 122.0 3.6 1.6 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 GAP83641.1 - 2.4e-17 63.4 0.0 6e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 GAP83641.1 - 4.1e-05 23.1 0.0 9.3e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAP83641.1 - 0.00016 21.4 0.3 0.00042 20.1 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain zf-C2H2_4 PF13894.6 GAP83642.1 - 0.094 13.6 4.7 0.49 11.4 1.1 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Ufd2P_core PF10408.9 GAP83643.1 - 2.3e-212 707.0 4.0 3.1e-212 706.6 4.0 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 GAP83643.1 - 1e-19 70.5 1.4 4e-19 68.5 1.4 2.1 1 0 0 1 1 1 1 U-box domain V-SNARE PF05008.15 GAP83643.1 - 0.0027 18.0 3.4 0.2 12.1 0.1 3.7 4 0 0 4 4 4 1 Vesicle transport v-SNARE protein N-terminus Rubella_Capsid PF05750.11 GAP83643.1 - 0.041 13.5 2.6 0.071 12.7 2.6 1.3 1 0 0 1 1 1 0 Rubella capsid protein RPW8 PF05659.11 GAP83643.1 - 0.11 12.2 0.9 0.51 10.0 0.1 2.4 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Halogen_Hydrol PF10112.9 GAP83643.1 - 0.13 12.2 1.7 3.5 7.6 0.1 2.9 2 1 1 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Nup54 PF13874.6 GAP83643.1 - 0.69 10.0 4.0 4.3 7.4 0.0 3.2 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 zf-ZPR1 PF03367.13 GAP83643.1 - 2.1 8.2 4.1 3.5 7.5 0.4 2.7 3 0 0 3 3 3 0 ZPR1 zinc-finger domain Gram_pos_anchor PF00746.21 GAP83644.1 - 3.4 7.7 5.3 6.3 6.8 5.3 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Epimerase PF01370.21 GAP83645.1 - 3e-15 56.3 0.0 4.4e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAP83645.1 - 4.7e-11 42.2 0.0 6.9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAP83645.1 - 1.9e-08 33.8 0.2 8.7e-07 28.4 0.2 2.3 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 GAP83645.1 - 2.7e-08 33.6 0.0 4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAP83645.1 - 5.1e-08 33.0 0.0 7.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAP83645.1 - 5.3e-05 22.5 0.0 7.3e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAP83645.1 - 0.005 16.8 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 GAP83645.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 GAP83645.1 - 0.071 12.7 0.1 0.12 12.0 0.1 1.4 1 1 0 1 1 1 0 NmrA-like family zf-C2H2 PF00096.26 GAP83647.1 - 4e-18 64.8 30.4 4.2e-05 23.8 0.7 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP83647.1 - 3.7e-13 49.3 36.2 2.1e-05 24.7 1.8 5.4 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP83647.1 - 2.5e-06 27.9 36.2 0.0072 17.1 0.5 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP83647.1 - 0.00027 21.1 1.6 4.2 7.8 0.0 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP83647.1 - 0.018 15.4 8.0 0.3 11.5 0.1 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 GAP83647.1 - 0.032 14.0 6.2 0.059 13.1 2.4 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type MFS_1 PF07690.16 GAP83648.1 - 1.5e-19 70.2 39.9 1.4e-18 67.0 34.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP83648.1 - 5.8e-06 25.4 4.3 5.8e-06 25.4 4.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Mito_carr PF00153.27 GAP83649.1 - 1.5e-43 146.6 9.6 8.1e-16 57.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Dioxygenase_C PF00775.21 GAP83651.1 - 4.5e-07 29.5 0.0 6.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase SelK_SelG PF10961.8 GAP83651.1 - 0.0094 16.5 2.9 0.032 14.8 2.9 1.9 1 0 0 1 1 1 1 Selenoprotein SelK_SelG DUF4148 PF13663.6 GAP83651.1 - 2.6 8.3 6.1 0.27 11.4 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) adh_short_C2 PF13561.6 GAP83652.1 - 2.6e-53 181.0 4.9 2.3e-33 115.7 1.5 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP83652.1 - 1.6e-42 145.2 3.7 7.3e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAP83652.1 - 8.6e-09 35.6 1.9 1.3e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 GAP83652.1 - 0.029 13.8 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 GAP83652.1 - 0.071 13.8 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_12 PF01670.16 GAP83653.1 - 3e-47 161.4 15.0 3.5e-47 161.2 15.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 LRR_6 PF13516.6 GAP83654.1 - 0.16 12.1 2.9 14 6.1 0.2 4.0 3 0 0 3 3 3 0 Leucine Rich repeat zf-C2H2 PF00096.26 GAP83655.1 - 0.0041 17.5 0.3 0.0092 16.4 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP83655.1 - 0.041 14.7 0.2 0.089 13.7 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger FOXP-CC PF16159.5 GAP83655.1 - 0.082 13.5 0.0 0.24 12.1 0.0 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF1770 PF08589.10 GAP83655.1 - 1.1 10.2 8.6 5.3 8.1 2.6 2.6 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) Hexapep PF00132.24 GAP83656.1 - 1e-05 25.0 5.1 0.16 11.7 0.0 4.1 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 GAP83656.1 - 0.0067 14.6 1.0 0.027 12.6 0.4 1.8 1 1 0 2 2 2 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 GAP83656.1 - 0.0084 16.5 0.0 0.019 15.3 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 GAP83656.1 - 0.03 13.3 0.9 0.078 11.9 0.9 1.6 1 1 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 GAP83656.1 - 0.037 13.8 6.8 13 5.6 0.1 3.7 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Spt20 PF12090.8 GAP83658.1 - 7.8e-48 163.1 0.0 7.8e-48 163.1 0.0 3.4 2 1 0 2 2 2 1 Spt20 family PAT1 PF09770.9 GAP83658.1 - 0.00055 18.4 34.0 0.00084 17.8 34.0 1.4 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 GAP83658.1 - 3.9 6.3 33.4 5.9 5.8 33.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ATG27 PF09451.10 GAP83661.1 - 2.5e-90 302.9 0.0 2.9e-90 302.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 GAP83661.1 - 0.16 12.1 0.1 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat Trypan_PARP PF05887.11 GAP83661.1 - 0.96 9.4 5.1 1.8 8.5 5.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Coprogen_oxidas PF01218.18 GAP83662.1 - 7.8e-145 481.1 0.0 9.4e-145 480.9 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Peptidase_C12 PF01088.21 GAP83663.1 - 2.7e-37 128.6 0.0 3.3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 bZIP_1 PF00170.21 GAP83664.1 - 9.3e-05 22.5 9.6 0.00012 22.0 9.6 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAP83664.1 - 0.00024 21.1 14.4 0.00072 19.6 14.4 1.7 1 1 0 1 1 1 1 Basic region leucine zipper MCC-bdg_PDZ PF10506.9 GAP83664.1 - 0.00026 21.0 0.4 0.00042 20.3 0.4 1.3 1 0 0 1 1 1 1 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_Maf PF03131.17 GAP83664.1 - 0.0018 18.7 4.6 0.0026 18.2 4.6 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Takusan PF04822.13 GAP83664.1 - 0.017 15.0 2.6 0.029 14.2 2.6 1.4 1 0 0 1 1 1 0 Takusan Clat_adaptor_s PF01217.20 GAP83665.1 - 1.7e-44 151.2 0.0 2.9e-44 150.4 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Mito_fiss_reg PF05308.11 GAP83666.1 - 0.25 11.4 6.9 0.32 11.1 6.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 GAP83666.1 - 3.4 7.7 19.5 1.8 8.7 17.5 1.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 GAP83666.1 - 9.1 5.7 13.6 12 5.3 13.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-CSL PF05207.13 GAP83668.1 - 2.6e-13 49.5 0.0 2.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 CSL zinc finger ABC_membrane_2 PF06472.15 GAP83669.1 - 1.2e-101 339.6 0.2 1.9e-101 339.0 0.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAP83669.1 - 1.8e-17 64.2 0.0 3.7e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAP83669.1 - 0.00027 20.8 0.0 0.00054 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAP83669.1 - 0.013 15.9 0.4 0.32 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 GAP83669.1 - 0.013 16.0 0.2 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAP83669.1 - 0.081 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 GAP83669.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RuvB_N PF05496.12 GAP83669.1 - 0.14 11.9 0.0 0.42 10.4 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAP83669.1 - 0.15 12.4 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAP83669.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 GAP83669.1 - 0.18 11.1 0.0 0.56 9.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TRAM1 PF08390.11 GAP83670.1 - 0.071 12.8 3.2 0.14 11.8 3.2 1.5 1 0 0 1 1 1 0 TRAM1-like protein HET PF06985.11 GAP83671.1 - 0.047 14.0 0.7 1.8 8.9 0.0 2.5 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) HET PF06985.11 GAP83672.1 - 0.0022 18.4 0.8 0.089 13.1 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ATP-synt_8 PF00895.20 GAP83673.1 - 9.5 6.8 6.2 9.1 6.8 0.8 2.9 3 0 0 3 3 3 0 ATP synthase protein 8 MFS_1 PF07690.16 GAP83674.1 - 3.7e-39 134.7 53.9 1.7e-32 112.7 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP83674.1 - 3e-38 131.9 21.1 7.2e-38 130.6 21.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.8 GAP83674.1 - 2.4e-05 23.2 9.0 0.00021 20.1 2.3 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_5 PF05631.14 GAP83674.1 - 0.007 15.3 1.1 0.084 11.8 0.3 2.1 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Esterase_phd PF10503.9 GAP83675.1 - 6.4e-21 74.9 0.9 9.8e-21 74.3 0.9 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 GAP83675.1 - 9.2e-12 44.9 1.8 1.3e-11 44.3 1.8 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 GAP83675.1 - 5e-06 25.7 1.8 7.2e-06 25.1 1.8 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP83675.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AIP3 PF03915.13 GAP83676.1 - 4.4e-158 526.7 12.8 7.6e-158 525.9 12.8 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 FliL PF03748.14 GAP83676.1 - 0.011 16.3 0.2 0.19 12.3 0.1 3.1 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL RasGAP_C PF03836.15 GAP83676.1 - 0.074 13.2 7.7 1.7 8.8 0.5 4.8 5 1 0 5 5 5 0 RasGAP C-terminus DUF2935 PF11155.8 GAP83676.1 - 0.24 11.7 1.2 1.4 9.3 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) GNVR PF13807.6 GAP83676.1 - 0.28 11.2 1.8 1.7 8.6 0.3 2.6 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase MIP-T3_C PF17749.1 GAP83676.1 - 0.63 10.0 14.7 0.38 10.7 2.8 3.4 3 1 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region NPV_P10 PF05531.12 GAP83676.1 - 0.89 10.1 10.8 0.17 12.4 0.5 4.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.14 GAP83676.1 - 1.9 8.8 19.7 0.82 10.0 0.9 4.4 2 1 2 4 4 4 0 Outer membrane protein (OmpH-like) Med11 PF10280.9 GAP83676.1 - 2.2 8.8 9.0 2.3 8.7 0.1 3.8 3 2 0 3 3 3 0 Mediator complex protein P120R PF08062.11 GAP83676.1 - 2.8 8.4 7.8 10 6.6 7.8 2.0 1 0 0 1 1 1 0 P120R (NUC006) repeat DUF1664 PF07889.12 GAP83676.1 - 6 6.9 12.1 3.3 7.8 0.3 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) LsmAD PF06741.13 GAP83677.1 - 2.9e-28 98.2 3.4 2.9e-28 98.2 3.4 2.3 2 0 0 2 2 2 1 LsmAD domain DUF677 PF05055.12 GAP83677.1 - 0.14 11.0 0.1 0.23 10.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) LPMO_10 PF03067.15 GAP83678.1 - 0.031 14.9 0.2 0.13 13.0 0.0 2.0 2 1 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Serglycin PF04360.12 GAP83678.1 - 0.045 13.7 3.0 0.14 12.1 3.0 1.8 1 0 0 1 1 1 0 Serglycin Glyco_hydro_61 PF03443.14 GAP83678.1 - 0.083 12.8 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 61 SUIM_assoc PF16619.5 GAP83679.1 - 0.013 15.5 8.8 0.053 13.6 1.2 2.5 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3408 PF11888.8 GAP83679.1 - 0.043 14.0 0.8 1.3 9.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3408) BSP_II PF05432.11 GAP83679.1 - 0.19 11.4 7.9 2.5 7.7 1.5 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.10 GAP83679.1 - 0.6 10.5 2.9 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BRO1 PF03097.18 GAP83680.1 - 3.1e-119 398.3 0.0 4.4e-119 397.8 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GAP83680.1 - 7.9e-79 265.0 3.8 7.9e-79 265.0 3.8 1.8 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV DUF604 PF04646.12 GAP83681.1 - 1.5e-10 40.9 0.0 1.4e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF604 Fringe PF02434.16 GAP83681.1 - 6.4e-09 35.6 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Fringe-like 2-oxoacid_dh PF00198.23 GAP83682.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) HMGL-like PF00682.19 GAP83683.1 - 2e-43 148.9 0.0 5.7e-43 147.4 0.0 1.6 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab PF00006.25 GAP83684.1 - 3.3e-66 223.0 0.0 4.5e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAP83684.1 - 3.3e-11 43.5 0.5 6.1e-11 42.7 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Aldose_epim PF01263.20 GAP83685.1 - 2.8e-47 161.5 0.6 3.7e-47 161.1 0.6 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Pex14_N PF04695.13 GAP83686.1 - 0.052 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_3 PF01596.17 GAP83687.1 - 3.2e-22 78.8 0.0 3.9e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 GAP83687.1 - 7.6e-09 36.6 0.1 1.4e-08 35.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAP83687.1 - 0.00087 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TrmK PF04816.12 GAP83687.1 - 0.035 13.6 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_15 PF09445.10 GAP83687.1 - 0.083 12.5 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Diphthamide_syn PF01866.17 GAP83688.1 - 3.4e-116 387.9 0.0 4.4e-116 387.6 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF3328 PF11807.8 GAP83689.1 - 1.9e-21 76.8 1.0 2.6e-21 76.4 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SKG6 PF08693.10 GAP83690.1 - 0.00024 20.4 0.0 0.00046 19.5 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 GAP83690.1 - 0.071 12.9 0.1 0.095 12.5 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2407_C PF13373.6 GAP83690.1 - 0.17 12.1 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain HET PF06985.11 GAP83691.1 - 4.2e-12 46.6 2.5 3.7e-10 40.3 0.2 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 GAP83692.1 - 1.5e-23 83.7 0.6 3e-23 82.8 0.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1996 PF09362.10 GAP83693.1 - 2.9e-68 230.4 0.1 3.8e-68 230.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NACHT PF05729.12 GAP83694.1 - 8.4e-07 29.0 0.4 4.7e-06 26.6 0.4 2.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP83694.1 - 1.1e-05 25.9 0.1 1.1e-05 25.9 0.1 2.4 3 0 0 3 3 2 1 AAA ATPase domain SesA PF17107.5 GAP83694.1 - 0.00037 20.7 0.1 0.001 19.2 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ATPase_2 PF01637.18 GAP83694.1 - 0.00045 20.2 0.0 0.0009 19.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 GAP83694.1 - 0.004 17.5 0.0 0.0086 16.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA PF00004.29 GAP83694.1 - 0.0047 17.4 0.0 0.0098 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 GAP83694.1 - 0.0088 15.2 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 GAP83694.1 - 0.011 16.0 0.0 0.039 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAP83694.1 - 0.016 15.7 0.0 0.063 13.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter ATP-synt_ab PF00006.25 GAP83694.1 - 0.023 14.4 0.0 0.12 12.0 0.1 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 GAP83694.1 - 0.028 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 GAP83694.1 - 0.035 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad4 PF03835.15 GAP83694.1 - 0.047 13.4 0.3 0.85 9.3 0.0 2.2 1 1 1 2 2 2 0 Rad4 transglutaminase-like domain TPR_1 PF00515.28 GAP83694.1 - 0.14 12.0 1.8 24 5.0 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_14 PF13173.6 GAP83694.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain TPR_2 PF07719.17 GAP83694.1 - 0.2 11.9 4.9 11 6.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat RTP1_C1 PF10363.9 GAP83695.1 - 1.7e-25 89.4 0.1 4.8e-25 87.9 0.1 1.9 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 GAP83695.1 - 1.8e-12 46.7 2.4 1.8e-12 46.7 2.4 2.3 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 2 DUF5535 PF17687.1 GAP83695.1 - 0.016 15.3 0.1 0.046 13.9 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5535) DUF1977 PF09320.11 GAP83696.1 - 4e-27 94.5 0.0 8.2e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 GAP83696.1 - 4.4e-19 68.4 0.1 7.6e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain PWWP PF00855.17 GAP83696.1 - 0.076 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 PWWP domain CPP1-like PF11833.8 GAP83697.1 - 0.0097 15.6 0.3 0.01 15.5 0.3 1.2 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like ATP19 PF11022.8 GAP83697.1 - 0.07 13.5 0.1 2.3 8.6 0.0 2.2 2 0 0 2 2 2 0 ATP synthase subunit K Y_phosphatase2 PF03162.13 GAP83698.1 - 9.7e-43 145.6 0.0 1.4e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 GAP83698.1 - 1.1e-07 32.1 0.0 1.4e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GAP83698.1 - 0.0025 17.6 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAP83698.1 - 0.0068 16.0 0.0 0.015 14.8 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DAO PF01266.24 GAP83699.1 - 6.6e-29 101.6 0.0 8.4e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP83699.1 - 0.0011 18.3 0.0 0.0033 16.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAP83699.1 - 0.0041 17.5 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 GAP83699.1 - 0.0045 17.5 1.6 0.012 16.2 0.6 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP83699.1 - 0.0054 16.9 0.3 0.012 15.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAP83699.1 - 0.0099 15.0 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAP83699.1 - 0.013 14.8 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAP83699.1 - 0.066 12.5 0.1 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Het-C PF07217.11 GAP83701.1 - 7.5e-280 929.3 0.0 9.1e-280 929.0 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C TctA PF01970.16 GAP83701.1 - 0.048 12.4 0.1 0.079 11.7 0.1 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Ydc2-catalyt PF09159.10 GAP83702.1 - 4.1e-61 207.2 0.0 5e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 GAP83702.1 - 1.9e-07 30.7 0.0 5.9e-06 25.9 0.1 2.5 2 0 0 2 2 2 1 SAP domain Pox_A22 PF04848.13 GAP83702.1 - 0.019 15.1 0.0 2.2 8.4 0.0 2.6 3 0 0 3 3 3 0 Poxvirus A22 protein Pyr_redox_2 PF07992.14 GAP83703.1 - 4.7e-53 180.3 0.1 7.4e-53 179.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAP83703.1 - 1.9e-33 115.0 0.2 2.5e-32 111.4 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAP83703.1 - 5.8e-16 58.8 0.1 1.9e-15 57.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP83703.1 - 1.6e-07 30.9 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Ntox47 PF15540.6 GAP83703.1 - 0.018 15.3 0.2 0.04 14.2 0.2 1.5 1 0 0 1 1 1 0 Bacterial toxin 47 K_oxygenase PF13434.6 GAP83703.1 - 0.025 13.7 0.0 0.17 11.0 0.0 1.9 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) SOG2 PF10428.9 GAP83704.1 - 3.1e-67 227.9 0.0 3.2e-44 152.0 0.0 4.6 4 1 1 5 5 5 2 RAM signalling pathway protein LRR_8 PF13855.6 GAP83704.1 - 3.4e-15 55.5 8.9 4e-07 29.7 1.9 3.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 GAP83704.1 - 5.6e-13 48.9 8.1 1.9e-06 28.1 0.1 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAP83704.1 - 0.003 17.9 6.3 7.6 7.5 0.2 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 GAP83704.1 - 0.41 10.8 10.2 6.1 7.2 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat Helicase_C PF00271.31 GAP83705.1 - 5.5e-18 65.3 0.0 4.9e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 GAP83705.1 - 7.2e-16 58.5 0.0 1.8e-15 57.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 GAP83705.1 - 4.7e-12 46.4 4.5 1.2e-11 45.1 4.5 1.7 1 0 0 1 1 1 1 RecQ zinc-binding GCN5L1 PF06320.13 GAP83706.1 - 5.4e-16 58.8 1.3 8.2e-16 58.2 1.3 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Rootletin PF15035.6 GAP83706.1 - 0.0028 17.7 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CREPT PF16566.5 GAP83706.1 - 0.033 14.4 0.8 0.056 13.6 0.8 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Spc7 PF08317.11 GAP83706.1 - 0.037 12.9 1.4 0.055 12.3 1.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2968 PF11180.8 GAP83706.1 - 0.073 12.7 3.8 0.1 12.2 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Steroid_dh PF02544.16 GAP83707.1 - 1.2e-30 106.5 0.6 1.7e-30 106.0 0.6 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 GAP83707.1 - 0.00016 22.0 0.6 0.00035 20.9 0.6 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 GAP83707.1 - 0.00028 20.5 0.2 0.00045 19.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) zf-TRAF PF02176.18 GAP83708.1 - 2e-14 54.0 23.8 3.2e-06 27.7 2.9 3.7 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 GAP83708.1 - 3.1e-07 30.1 8.0 3.1e-07 30.1 8.0 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP83708.1 - 5e-07 29.6 4.6 5e-07 29.6 4.6 3.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-TRAF_2 PF15965.5 GAP83708.1 - 1.3e-06 28.8 24.2 7e-06 26.4 8.5 2.8 2 1 0 2 2 2 2 TRAF-like zinc-finger zf-C3HC4_3 PF13920.6 GAP83708.1 - 1.7e-06 27.8 5.4 1.7e-06 27.8 5.4 3.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP83708.1 - 5e-06 26.4 5.8 5e-06 26.4 5.8 3.0 2 2 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAP83708.1 - 3.5e-05 24.1 7.2 3.5e-05 24.1 7.2 3.9 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 GAP83708.1 - 9.3e-05 22.2 8.2 9.3e-05 22.2 8.2 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAP83708.1 - 0.00011 22.2 8.3 0.00011 22.2 8.3 2.7 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 GAP83708.1 - 0.0014 18.7 3.3 0.0014 18.7 3.3 2.8 2 1 0 2 2 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 GAP83708.1 - 0.013 15.6 1.3 0.013 15.6 1.3 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 GAP83708.1 - 0.023 14.6 0.6 0.023 14.6 0.6 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 GAP83708.1 - 0.028 14.7 7.3 0.028 14.7 7.3 4.0 2 2 1 3 3 2 0 RING-H2 zinc finger domain Sina PF03145.16 GAP83708.1 - 0.63 10.0 19.6 0.1 12.5 1.0 3.3 1 1 2 3 3 2 0 Seven in absentia protein family zf-P11 PF03854.14 GAP83708.1 - 5.2 6.8 9.9 3 7.6 1.9 3.0 1 1 1 2 2 2 0 P-11 zinc finger DENN PF02141.21 GAP83709.1 - 9.4e-40 136.6 0.0 1.6e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAP83709.1 - 8.6e-07 29.6 0.0 3.6e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 uDENN domain Inovirus_Gp2 PF11726.8 GAP83709.1 - 1.9 8.4 7.0 0.16 11.9 1.3 2.2 3 0 0 3 3 3 0 Inovirus Gp2 PCRF PF03462.18 GAP83709.1 - 2.3 8.0 11.7 2.1 8.1 7.2 2.4 1 1 1 2 2 2 0 PCRF domain CENP-K PF11802.8 GAP83709.1 - 6.9 6.2 18.1 2.7 7.5 7.1 2.2 1 1 1 2 2 2 0 Centromere-associated protein K DUF4448 PF14610.6 GAP83711.1 - 0.053 13.3 0.0 0.073 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Pirin PF02678.16 GAP83713.1 - 1.6e-29 102.0 0.0 2.7e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 GAP83713.1 - 4.3e-23 81.7 0.0 9.4e-22 77.3 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 GAP83713.1 - 3.3e-05 23.5 0.5 0.00012 21.8 0.4 1.9 2 0 0 2 2 2 1 Cupin domain DUF948 PF06103.11 GAP83713.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Glyco_hydro_11 PF00457.17 GAP83715.1 - 5.5e-69 231.4 13.5 6.6e-69 231.1 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Ank_2 PF12796.7 GAP83716.1 - 1e-52 176.6 14.2 3.2e-11 43.6 0.6 5.9 3 1 5 8 8 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP83716.1 - 1.6e-41 140.1 8.0 7.1e-10 39.2 0.1 6.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP83716.1 - 2.3e-37 126.5 21.7 1.6e-10 41.0 0.4 5.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 GAP83716.1 - 1.3e-31 107.7 13.6 3.7e-06 27.1 0.1 7.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 GAP83716.1 - 1.9e-29 98.4 8.3 0.00047 20.4 0.0 8.1 8 0 0 8 8 7 6 Ankyrin repeat NACHT PF05729.12 GAP83716.1 - 5.2e-08 33.0 0.0 1.4e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 GAP83716.1 - 2.1e-07 30.5 0.5 5.1e-07 29.3 0.2 1.8 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 GAP83716.1 - 2e-05 25.0 2.2 0.00072 20.0 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain V-SNARE PF05008.15 GAP83716.1 - 0.00069 20.0 4.9 0.0013 19.1 0.6 3.1 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus NB-ARC PF00931.22 GAP83716.1 - 0.003 16.8 0.0 0.021 14.0 0.0 2.4 1 1 1 2 2 2 1 NB-ARC domain SesA PF17107.5 GAP83716.1 - 0.0032 17.7 1.2 0.0091 16.2 0.6 2.0 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases FRB_dom PF08771.11 GAP83716.1 - 0.036 14.5 0.3 0.15 12.5 0.3 2.1 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain DUF2383 PF09537.10 GAP83716.1 - 0.051 13.9 0.1 0.23 11.8 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) P4Ha_N PF08336.11 GAP83716.1 - 0.082 12.9 0.7 0.3 11.1 0.3 2.2 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF1451 PF07295.11 GAP83716.1 - 1.2 9.2 4.5 12 5.9 0.1 2.6 2 1 0 2 2 2 0 Zinc-ribbon containing domain Syntaxin_2 PF14523.6 GAP83716.1 - 1.8 9.0 9.1 2.3 8.6 0.7 3.5 2 1 1 3 3 3 0 Syntaxin-like protein But2 PF09792.9 GAP83717.1 - 3e-06 27.7 0.1 2.9e-05 24.5 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3712 PF12505.8 GAP83718.1 - 3.5e-10 40.2 0.1 5.6e-07 29.9 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 GAP83718.1 - 0.018 15.6 0.9 12 6.4 0.3 4.1 4 0 0 4 4 4 0 Late embryogenesis abundant protein OTCace PF00185.24 GAP83719.1 - 2.9e-44 150.9 0.0 4.4e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 GAP83719.1 - 8e-41 139.5 0.1 1.1e-40 139.1 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Helicase_C_3 PF13625.6 GAP83719.1 - 0.17 12.1 0.1 0.67 10.1 0.1 2.1 2 1 0 2 2 2 0 Helicase conserved C-terminal domain ACT PF01842.25 GAP83720.1 - 5e-14 51.8 0.1 9.5e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ALS_ss_C PF10369.9 GAP83720.1 - 8.8e-14 51.5 0.0 8.3e-13 48.4 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 GAP83720.1 - 3.2e-08 33.3 0.0 6.9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 GAP83720.1 - 0.1 12.6 0.0 23 5.1 0.0 2.6 2 0 0 2 2 2 0 ACT domain KH_1 PF00013.29 GAP83721.1 - 1.6e-09 37.5 0.0 2.4e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 KH domain Ank_2 PF12796.7 GAP83722.1 - 4.2e-49 165.0 0.2 8.2e-17 61.6 0.1 7.2 4 2 2 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP83722.1 - 1.1e-37 127.9 0.3 2.6e-08 34.3 0.0 7.9 5 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP83722.1 - 3.3e-35 119.7 1.4 2e-08 34.3 0.0 7.3 8 1 0 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 GAP83722.1 - 7e-31 105.3 3.6 2.2e-06 27.8 0.1 11.2 12 0 0 12 12 12 5 Ankyrin repeat Ank_3 PF13606.6 GAP83722.1 - 2.7e-28 94.9 3.8 0.026 15.0 0.0 11.8 13 0 0 13 13 13 7 Ankyrin repeat AAA_16 PF13191.6 GAP83722.1 - 5e-06 27.0 0.0 2.1e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GAP83722.1 - 8.9e-06 25.7 0.0 4.2e-05 23.5 0.0 2.1 2 1 0 2 2 2 1 NACHT domain TsaE PF02367.17 GAP83722.1 - 0.0021 18.1 0.0 0.008 16.2 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 GAP83722.1 - 0.0043 17.3 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain MCR_gamma PF02240.16 GAP83723.1 - 0.092 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit Peptidase_S8 PF00082.22 GAP83724.1 - 8e-12 45.0 0.0 2.4e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 GAP83724.1 - 2.1e-08 34.6 3.9 0.00012 22.5 0.8 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP83724.1 - 4.8e-07 29.9 2.6 0.015 15.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP83724.1 - 1.6e-05 24.9 4.8 0.19 12.4 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 GAP83724.1 - 0.0016 19.0 1.9 1.2 9.8 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 GAP83724.1 - 0.02 15.3 0.7 0.6 10.7 0.3 3.6 2 1 0 2 2 2 0 Ankyrin repeat DUF974 PF06159.13 GAP83725.1 - 1.2e-78 264.3 0.0 1.5e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.21 GAP83726.1 - 2.5e-54 184.0 0.0 4.2e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 GAP83726.1 - 7.8e-15 55.4 0.0 1.9e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 GAP83726.1 - 3.3e-13 49.4 0.2 6.5e-13 48.5 0.2 1.5 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.16 GAP83726.1 - 0.015 15.6 7.2 0.028 14.8 7.2 1.4 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 GAP83726.1 - 2.6 8.0 8.6 4.9 7.1 8.6 1.4 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 GAP83726.1 - 9.6 6.2 10.0 16 5.5 10.0 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MMR_HSR1 PF01926.23 GAP83727.1 - 2.9e-05 24.1 0.0 0.37 10.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GET2 PF08690.10 GAP83728.1 - 1.2e-38 133.6 0.0 3.7e-38 132.0 0.0 1.7 1 1 0 1 1 1 1 GET complex subunit GET2 DUF2967 PF11179.8 GAP83729.1 - 0.0012 17.0 4.7 0.0016 16.6 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2967) RNA_pol_3_Rpc31 PF11705.8 GAP83729.1 - 0.0041 17.4 6.8 0.0053 17.1 6.8 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 GAP83729.1 - 0.0042 16.6 3.5 0.0052 16.3 3.5 1.1 1 0 0 1 1 1 1 SDA1 PPP4R2 PF09184.11 GAP83729.1 - 0.0073 15.9 4.2 0.0087 15.7 4.2 1.1 1 0 0 1 1 1 1 PPP4R2 Cwf_Cwc_15 PF04889.12 GAP83729.1 - 0.026 14.3 5.3 0.033 13.9 5.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAP83729.1 - 0.25 10.6 14.8 0.37 10.1 14.8 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 GAP83729.1 - 1 7.5 8.4 1.3 7.2 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAP83729.1 - 1.5 6.9 12.4 1.9 6.6 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 GAP83729.1 - 4 7.3 7.6 5.9 6.7 7.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Glyco_hydro_18 PF00704.28 GAP83731.1 - 8.7e-27 94.7 0.2 1.5e-26 93.8 0.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SART-1 PF03343.13 GAP83732.1 - 4.5e-181 603.7 61.3 5.1e-181 603.5 61.3 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.21 GAP83733.1 - 1.4e-104 350.4 0.1 1.9e-104 350.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 GAP83733.1 - 3.5e-33 113.4 1.1 7.3e-33 112.4 1.1 1.6 1 0 0 1 1 1 1 Starch binding domain Fructosamin_kin PF03881.14 GAP83735.1 - 2.3e-72 243.6 0.0 2.7e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 GAP83735.1 - 0.0023 17.9 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GAP83735.1 - 0.061 12.2 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ATP-grasp_2 PF08442.10 GAP83736.1 - 7.4e-77 257.5 0.3 7.4e-77 257.5 0.3 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 GAP83736.1 - 1e-26 93.6 0.5 2e-26 92.6 0.5 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 GAP83736.1 - 1.4e-10 41.0 0.0 3.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAP83736.1 - 0.00038 20.3 1.1 0.015 15.1 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain p450 PF00067.22 GAP83737.1 - 5.5e-55 186.9 0.0 7.6e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HSF_DNA-bind PF00447.17 GAP83739.1 - 6.2e-30 103.7 0.7 1.2e-29 102.8 0.7 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Aa_trans PF01490.18 GAP83741.1 - 1.7e-55 188.4 34.5 1.9e-55 188.3 34.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GMC_oxred_N PF00732.19 GAP83742.1 - 5.6e-32 111.3 0.0 2.2e-30 106.0 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP83742.1 - 1.1e-29 103.8 0.0 2.3e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAP83742.1 - 2.3e-06 27.0 0.0 0.0076 15.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAP83742.1 - 2.4e-05 23.7 0.1 6.6e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP83742.1 - 4.6e-05 23.6 0.1 0.00017 21.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP83742.1 - 0.0055 16.3 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAP83742.1 - 0.006 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAP83742.1 - 0.0063 15.8 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP83742.1 - 0.0068 15.5 0.1 0.24 10.4 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAP83742.1 - 0.013 14.7 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 GAP83742.1 - 0.059 12.7 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAP83742.1 - 0.059 12.1 0.0 0.095 11.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 GAP83742.1 - 0.081 13.5 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SDA1 PF05285.12 GAP83743.1 - 3.4e-84 283.2 61.9 7.3e-83 278.9 51.0 3.1 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 GAP83743.1 - 1.2e-17 64.0 0.1 2.8e-17 62.8 0.1 1.7 1 0 0 1 1 1 1 NUC130/3NT domain Pkinase PF00069.25 GAP83744.1 - 2.4e-51 174.6 0.0 3.2e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP83744.1 - 6.5e-40 137.0 0.0 9.7e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP83744.1 - 0.001 18.5 0.0 0.0046 16.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAP83744.1 - 0.0019 17.1 0.0 0.0047 15.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 GAP83744.1 - 0.0022 17.0 0.0 0.11 11.4 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 GAP83744.1 - 0.029 14.3 0.0 0.31 10.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 GAP83744.1 - 0.037 13.4 0.0 0.093 12.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2934 PF11154.8 GAP83744.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) His_Phos_1 PF00300.22 GAP83745.1 - 1.8e-24 86.5 0.3 6.7e-24 84.6 0.3 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DASH_Dad3 PF08656.10 GAP83746.1 - 5.7e-33 112.8 0.4 7e-33 112.5 0.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.15 GAP83747.1 - 6.1e-21 73.7 0.0 1.7e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 GAP83747.1 - 7.1e-17 61.2 0.1 1.2e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain CRR7 PF12095.8 GAP83747.1 - 0.0097 16.3 0.1 0.064 13.7 0.1 2.1 2 0 0 2 2 2 1 Protein CHLORORESPIRATORY REDUCTION 7 OAD_gamma PF04277.13 GAP83748.1 - 0.0077 16.8 0.8 0.01 16.4 0.5 1.4 1 1 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain S1FA PF04689.13 GAP83748.1 - 0.013 15.6 0.3 0.017 15.3 0.3 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA DUF5589 PF17672.1 GAP83748.1 - 0.061 13.3 0.1 0.069 13.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5589) DUF2556 PF10831.8 GAP83748.1 - 0.15 12.0 0.1 0.2 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) Vpu PF00558.19 GAP83748.1 - 0.16 11.8 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Vpu protein Ribosomal_L16 PF00252.18 GAP83750.1 - 8.7e-32 109.9 0.7 1.1e-31 109.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e bMG6 PF17962.1 GAP83750.1 - 0.15 12.2 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial macroglobulin domain 6 RFC1 PF08519.12 GAP83751.1 - 2.7e-57 193.4 0.0 8e-57 191.8 0.0 1.9 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 GAP83751.1 - 3.5e-15 56.2 0.0 8.3e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 GAP83751.1 - 2.5e-09 37.7 0.0 7.9e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAP83751.1 - 2.6e-06 27.5 0.0 5.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 GAP83751.1 - 0.00069 20.0 0.1 0.022 15.2 0.1 3.0 2 1 0 3 3 3 1 AAA ATPase domain DNA_pol3_delta PF06144.13 GAP83751.1 - 0.0007 19.4 0.1 0.003 17.3 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 GAP83751.1 - 0.0009 19.5 0.0 0.0027 18.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAP83751.1 - 0.0052 16.5 0.0 0.0052 16.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 GAP83751.1 - 0.011 15.6 0.0 2.6 7.9 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 GAP83751.1 - 0.014 15.6 0.0 0.052 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAP83751.1 - 0.02 15.4 0.1 0.02 15.4 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 GAP83751.1 - 0.03 14.6 1.6 0.17 12.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 GAP83751.1 - 0.04 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain PTCB-BRCT PF12738.7 GAP83751.1 - 0.041 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain RuvB_N PF05496.12 GAP83751.1 - 0.044 13.5 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 GAP83751.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 GAP83751.1 - 0.13 12.1 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 NTPase GrpE PF01025.19 GAP83753.1 - 2.7e-48 163.7 5.0 3.6e-48 163.4 5.0 1.1 1 0 0 1 1 1 1 GrpE DUF334 PF03904.13 GAP83753.1 - 0.069 12.7 1.4 0.096 12.2 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) RNA_pol_A_bac PF01000.26 GAP83754.1 - 1.5e-31 109.1 0.0 2.2e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAP83754.1 - 1.2e-18 66.3 0.0 1.6e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain FeS_assembly_P PF01883.19 GAP83754.1 - 0.078 13.2 0.2 2.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein Mito_carr PF00153.27 GAP83755.1 - 3.6e-50 167.9 0.8 4.3e-20 71.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.20 GAP83756.1 - 6.3e-47 160.1 0.1 1.4e-24 86.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 GAP83756.1 - 3.4e-25 88.3 0.0 7.4e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Calcipressin PF04847.12 GAP83757.1 - 2.1e-51 174.3 0.1 2.8e-51 173.9 0.1 1.2 1 0 0 1 1 1 1 Calcipressin Phage_cap_P2 PF05125.12 GAP83757.1 - 0.059 12.4 0.1 0.089 11.8 0.1 1.2 1 0 0 1 1 1 0 Phage major capsid protein, P2 family DUF2236 PF09995.9 GAP83758.1 - 8.9e-27 94.8 4.1 1.3e-26 94.2 4.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Neugrin PF06413.11 GAP83759.1 - 7.2e-14 52.3 0.2 1.3e-13 51.6 0.2 1.3 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 GAP83759.1 - 3.9e-06 27.1 0.5 7.3e-06 26.3 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Thump_like PF18096.1 GAP83759.1 - 0.038 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 THUMP domain-like ADH_zinc_N PF00107.26 GAP83760.1 - 4.3e-07 30.0 0.0 8.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP83760.1 - 0.00049 20.0 0.3 0.0011 18.8 0.2 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAP83760.1 - 0.013 16.5 0.0 0.026 15.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase p450 PF00067.22 GAP83762.1 - 4.4e-29 101.5 0.0 5.5e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FliX PF10768.9 GAP83762.1 - 0.17 12.4 0.1 0.31 11.5 0.1 1.3 1 0 0 1 1 1 0 Class II flagellar assembly regulator MFS_1 PF07690.16 GAP83763.1 - 2.5e-34 118.7 51.9 1.7e-33 116.0 51.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP83763.1 - 1.8e-17 63.0 21.6 2.7e-17 62.5 21.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP83763.1 - 7.7e-09 34.9 15.2 7.7e-09 34.9 15.2 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter Zn_clus PF00172.18 GAP83765.1 - 1.9e-06 27.9 9.8 4.4e-06 26.7 9.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 GAP83766.1 - 5e-72 242.8 0.0 8.2e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 GAP83766.1 - 2e-71 240.5 0.0 1.6e-70 237.6 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 GAP83766.1 - 2.1e-61 208.0 0.0 3.1e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.21 GAP83766.1 - 4.3e-51 174.3 0.1 9.6e-51 173.2 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAP83766.1 - 1.6e-49 168.8 0.1 2.8e-49 168.0 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 GAP83766.1 - 2.9e-48 164.1 0.1 1.9e-47 161.5 0.0 2.4 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 GAP83766.1 - 1.5e-32 112.8 0.0 1.4e-31 109.6 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 GAP83766.1 - 5.4e-29 100.6 0.0 1.5e-28 99.2 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 GAP83766.1 - 7.7e-19 67.8 4.2 1.5e-09 38.0 0.1 3.0 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 GAP83766.1 - 7e-16 58.8 0.0 3.5e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAP83766.1 - 1.3e-12 48.2 0.0 3.3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 GAP83766.1 - 5e-11 43.2 0.1 5.3e-10 39.9 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP83766.1 - 7.7e-11 42.1 0.0 2e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 GAP83766.1 - 9.8e-11 41.6 0.0 4.4e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 GAP83766.1 - 1.1e-09 38.8 0.1 1e-08 35.7 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP83766.1 - 6.2e-09 35.8 0.1 1.9e-08 34.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 GAP83766.1 - 2e-08 33.9 0.0 9.6e-08 31.7 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Ubie_methyltran PF01209.18 GAP83766.1 - 0.00049 19.5 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.19 GAP83766.1 - 0.00051 19.1 0.0 0.00093 18.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.9 GAP83766.1 - 0.00092 19.0 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase SAT PF16073.5 GAP83766.1 - 0.0015 18.3 0.6 0.11 12.2 0.9 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 GAP83766.1 - 0.0038 16.6 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C PF13193.6 GAP83766.1 - 0.052 14.5 0.0 0.21 12.6 0.0 2.2 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain WD40 PF00400.32 GAP83767.1 - 6.9e-12 45.7 5.8 0.024 15.5 0.3 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP83767.1 - 7.6e-05 22.9 0.0 4.4 7.7 0.0 4.8 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 GAP83767.1 - 0.02 14.5 0.1 0.88 9.1 0.0 3.5 3 1 1 4 4 4 0 PQQ-like domain Phage_CI_repr PF07022.13 GAP83767.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain WD40_like PF17005.5 GAP83767.1 - 0.15 11.4 1.4 12 5.1 0.1 2.5 2 0 0 2 2 2 0 WD40-like domain Rgp1 PF08737.10 GAP83768.1 - 8.8e-158 525.9 0.0 1.4e-157 525.2 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.22 GAP83768.1 - 0.011 16.2 0.0 0.27 11.7 0.0 2.7 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAP83768.1 - 0.021 14.9 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain COesterase PF00135.28 GAP83769.1 - 9.8e-76 255.7 0.0 1.5e-75 255.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP83769.1 - 2.1e-05 24.5 0.1 5.9e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP83769.1 - 0.057 12.9 0.2 0.15 11.6 0.1 1.6 1 1 1 2 2 2 0 Prolyl oligopeptidase family Ribonuclease_3 PF00636.26 GAP83771.1 - 1.1e-38 132.1 0.0 6.5e-22 78.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAP83771.1 - 2.1e-23 82.9 0.1 1.2e-13 51.4 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 GAP83771.1 - 3.1e-20 72.1 0.0 7.8e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 GAP83771.1 - 7.6e-19 68.1 0.1 3.7e-18 65.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAP83771.1 - 9e-18 64.6 0.0 1.8e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAP83771.1 - 3.2e-13 50.1 0.0 6e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3638 PF12340.8 GAP83771.1 - 0.017 14.4 0.2 0.032 13.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) DEAD_2 PF06733.15 GAP83771.1 - 0.15 11.7 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 Proteasome PF00227.26 GAP83772.1 - 1.8e-52 177.6 0.0 1.2e-28 99.9 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit RINGv PF12906.7 GAP83773.1 - 3.1e-11 43.2 4.5 3.1e-11 43.2 1.0 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 GAP83773.1 - 0.23 11.8 3.4 0.57 10.6 0.7 2.2 2 0 0 2 2 2 0 Ring finger domain Sigma_reg_N PF13800.6 GAP83773.1 - 0.49 10.7 2.2 1.5 9.2 0.5 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal PHD PF00628.29 GAP83773.1 - 0.85 9.6 4.4 0.44 10.5 1.9 1.8 2 0 0 2 2 2 0 PHD-finger Glyco_transf_34 PF05637.12 GAP83774.1 - 3.3e-71 239.8 0.0 4.1e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 GAP83774.1 - 0.0013 18.3 0.0 0.11 12.0 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 Pyridoxal_deC PF00282.19 GAP83775.1 - 5.7e-16 58.2 0.0 7.9e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAP83775.1 - 0.00099 18.2 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAP83775.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family BCDHK_Adom3 PF10436.9 GAP83777.1 - 3.1e-75 251.5 0.0 4.3e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAP83777.1 - 8.9e-09 35.9 0.0 1.7e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Packaging_FI PF14000.6 GAP83778.1 - 0.0053 17.2 0.8 0.056 13.9 0.0 2.3 2 0 0 2 2 2 1 DNA packaging protein FI APG6_N PF17675.1 GAP83778.1 - 0.036 14.6 6.9 0.03 14.8 5.1 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region FUSC PF04632.12 GAP83778.1 - 0.34 9.4 2.0 1 7.8 2.0 1.7 1 1 0 1 1 1 0 Fusaric acid resistance protein family WLM PF08325.10 GAP83779.1 - 2.7e-30 105.9 0.1 6.6e-30 104.6 0.1 1.7 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 GAP83779.1 - 0.0029 17.7 2.2 0.0047 17.0 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 GAP83779.1 - 0.0092 15.8 0.7 0.02 14.7 0.7 1.4 1 1 0 1 1 1 1 SprT-like family ER_lumen_recept PF00810.18 GAP83780.1 - 1.4e-53 181.7 5.7 2.4e-53 180.9 5.7 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 GAP83780.1 - 0.97 9.3 0.0 0.97 9.3 0.0 3.6 4 1 0 4 4 4 0 PQ loop repeat Adeno_E3_CR2 PF02439.15 GAP83781.1 - 0.15 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ctf8 PF09696.10 GAP83782.1 - 1e-42 145.8 0.1 1.8e-42 145.1 0.1 1.4 1 1 0 1 1 1 1 Ctf8 DUF3287 PF11690.8 GAP83782.1 - 0.15 11.8 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Ribosomal_S6e PF01092.19 GAP83783.1 - 1.5e-59 199.5 0.5 2.3e-59 198.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e Atg14 PF10186.9 GAP83783.1 - 1.8 7.6 8.3 2.5 7.1 8.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pribosyltran_N PF13793.6 GAP83784.1 - 4.8e-43 145.8 0.3 2.8e-42 143.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAP83784.1 - 1.1e-37 129.9 3.8 7.6e-33 114.1 2.0 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAP83784.1 - 9.6e-17 61.0 1.9 1.9e-16 60.0 0.8 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 GAP83784.1 - 0.0022 17.5 0.2 0.0036 16.8 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF4392 PF14336.6 GAP83784.1 - 0.027 13.9 0.1 0.039 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DUF2007 PF09413.10 GAP83784.1 - 0.12 12.6 0.1 1 9.6 0.0 2.5 3 0 0 3 3 3 0 Putative prokaryotic signal transducing protein TFIID_30kDa PF03540.13 GAP83785.1 - 1.1e-23 82.9 0.4 1.6e-23 82.3 0.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 GAP83785.1 - 0.027 15.0 1.1 0.027 15.0 1.1 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Cellulase PF00150.18 GAP83786.1 - 6.5e-55 186.5 7.0 7.7e-55 186.3 7.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF908 PF06012.12 GAP83787.1 - 3.2e-121 405.1 2.8 3.2e-121 405.1 2.8 3.1 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 GAP83787.1 - 3.6e-121 404.6 0.0 3.6e-121 404.6 0.0 5.0 4 1 0 4 4 4 1 Domain of Unknown Function (DUF913) HECT PF00632.25 GAP83787.1 - 7.6e-94 314.6 0.0 1.2e-93 314.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 GAP83787.1 - 4.3e-21 73.6 29.3 1.4e-07 30.7 1.9 5.4 4 1 1 5 5 5 3 Ubiquitin binding region TAF4 PF05236.14 GAP83787.1 - 0.84 9.3 15.3 2 8.1 15.3 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Bud13 PF09736.9 GAP83787.1 - 5.1 7.5 16.1 31 4.9 16.1 2.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex WW PF00397.26 GAP83788.1 - 3.8e-11 42.9 0.3 8.8e-11 41.7 0.3 1.7 1 0 0 1 1 1 1 WW domain Tubulin PF00091.25 GAP83789.1 - 1.2e-67 227.9 0.0 1.7e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAP83789.1 - 1.3e-48 164.3 0.0 2.2e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAP83789.1 - 0.0018 18.0 0.0 0.0055 16.4 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain EF-hand_4 PF12763.7 GAP83790.1 - 2.2e-34 117.5 0.0 5.2e-13 48.8 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 GAP83790.1 - 1.1e-06 28.9 0.0 0.00083 19.8 0.1 4.1 4 1 1 5 5 3 1 EF-hand domain pair UBA PF00627.31 GAP83790.1 - 3.5e-06 26.8 0.1 6.3e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Spc7 PF08317.11 GAP83790.1 - 0.00018 20.5 29.5 0.0045 15.9 14.6 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 GAP83790.1 - 0.0011 19.0 32.0 0.0068 16.5 17.1 2.7 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein EF-hand_1 PF00036.32 GAP83790.1 - 0.0017 17.8 0.3 8.7 6.2 0.0 4.5 6 0 0 6 6 4 0 EF hand TMF_TATA_bd PF12325.8 GAP83790.1 - 0.0043 17.2 22.5 0.043 14.0 3.6 3.3 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding COG2 PF06148.11 GAP83790.1 - 0.0057 16.7 15.2 0.047 13.8 3.5 2.4 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Myosin_tail_1 PF01576.19 GAP83790.1 - 0.014 13.2 28.0 0.032 12.0 28.0 1.4 1 1 0 1 1 1 0 Myosin tail DUF3584 PF12128.8 GAP83790.1 - 0.018 12.6 27.3 0.024 12.2 27.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LPP PF04728.13 GAP83790.1 - 0.046 14.1 14.4 0.24 11.8 3.2 3.9 2 2 1 3 3 3 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 GAP83790.1 - 0.082 12.9 30.5 0.02 14.9 9.8 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 GAP83790.1 - 0.1 12.8 32.9 0.13 12.4 10.4 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 GAP83790.1 - 0.14 11.8 31.3 1.5 8.4 31.6 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease EF-hand_6 PF13405.6 GAP83790.1 - 0.16 12.0 2.9 4.9 7.3 0.0 4.3 5 0 0 5 5 4 0 EF-hand domain TolA_bind_tri PF16331.5 GAP83790.1 - 0.19 11.8 34.3 0.19 11.8 11.0 4.2 3 1 1 5 5 4 0 TolA binding protein trimerisation DUF812 PF05667.11 GAP83790.1 - 0.23 10.3 27.0 0.14 11.1 23.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) ADIP PF11559.8 GAP83790.1 - 0.24 11.5 31.4 0.87 9.7 10.5 2.5 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding YkyA PF10368.9 GAP83790.1 - 0.25 11.0 18.4 1.5 8.4 15.9 2.6 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF4559 PF15112.6 GAP83790.1 - 0.26 10.9 13.3 0.41 10.3 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) APG6_N PF17675.1 GAP83790.1 - 0.31 11.6 31.4 0.41 11.2 9.7 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 GAP83790.1 - 0.33 11.0 16.6 0.6 10.1 4.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 GAP83790.1 - 0.37 10.5 24.8 4.4 7.0 14.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Csm1_N PF18504.1 GAP83790.1 - 0.41 11.0 21.6 0.044 14.1 2.4 3.9 2 2 1 4 4 4 0 Csm1 N-terminal domain BAR_3 PF16746.5 GAP83790.1 - 0.48 10.1 17.4 0.36 10.5 3.0 2.2 1 1 1 2 2 2 0 BAR domain of APPL family FUSC PF04632.12 GAP83790.1 - 1 7.8 7.2 1.5 7.2 7.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SPATA1_C PF15743.5 GAP83790.1 - 1.1 9.3 16.8 1.8 8.7 15.9 1.8 1 1 0 1 1 1 0 Spermatogenesis-associated C-terminus DUF724 PF05266.14 GAP83790.1 - 1.2 8.9 21.2 1.5 8.6 6.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PRKG1_interact PF15898.5 GAP83790.1 - 1.6 9.7 27.1 0.024 15.5 8.4 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain GAS PF13851.6 GAP83790.1 - 1.6 8.0 29.5 3.3 7.0 13.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 GAP83790.1 - 1.6 7.9 30.7 1.1 8.5 12.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Laminin_I PF06008.14 GAP83790.1 - 1.7 8.3 26.2 0.21 11.3 4.7 3.1 1 1 2 3 3 3 0 Laminin Domain I HMMR_N PF15905.5 GAP83790.1 - 1.7 8.0 25.6 2.8 7.3 25.6 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HMMR_C PF15908.5 GAP83790.1 - 3.1 8.0 16.0 6.4 7.0 16.0 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal DUF4472 PF14739.6 GAP83790.1 - 3.2 8.5 20.6 3 8.6 9.2 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Golgin_A5 PF09787.9 GAP83790.1 - 3.9 6.8 29.2 17 4.7 29.2 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 EzrA PF06160.12 GAP83790.1 - 4.1 5.5 20.7 11 4.0 20.8 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Atg14 PF10186.9 GAP83790.1 - 4.7 6.2 28.5 0.28 10.2 14.5 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 GAP83790.1 - 6.5 5.6 24.2 1.9 7.3 18.2 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Fez1 PF06818.15 GAP83790.1 - 6.6 7.1 25.8 2 8.8 13.1 2.2 1 1 1 2 2 2 0 Fez1 HOOK PF05622.12 GAP83790.1 - 7.3 4.6 26.3 12 3.9 20.6 2.2 1 1 1 2 2 2 0 HOOK protein FliJ PF02050.16 GAP83790.1 - 7.4 6.8 29.7 2 8.7 10.8 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein Occludin_ELL PF07303.13 GAP83790.1 - 8.2 7.2 13.6 9.7 7.0 2.6 2.8 1 1 1 2 2 2 0 Occludin homology domain MscS_porin PF12795.7 GAP83790.1 - 8.6 5.8 39.8 4.7 6.7 20.3 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Fib_alpha PF08702.10 GAP83790.1 - 9.9 6.3 22.4 3.3 7.9 8.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PHO4 PF01384.20 GAP83791.1 - 2.3e-88 296.5 11.6 2.6e-88 296.3 11.6 1.0 1 0 0 1 1 1 1 Phosphate transporter family Ribosomal_S8e PF01201.22 GAP83792.1 - 6.6e-55 185.0 1.0 7.8e-55 184.8 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e An_peroxidase PF03098.15 GAP83792.1 - 0.058 12.0 0.1 0.087 11.4 0.1 1.2 1 0 0 1 1 1 0 Animal haem peroxidase RabGAP-TBC PF00566.18 GAP83793.1 - 7.9e-49 166.2 0.2 7.7e-48 163.0 0.2 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 GAP83793.1 - 0.00054 20.1 9.4 0.00054 20.1 9.4 3.8 4 1 1 5 5 5 2 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 GAP83793.1 - 0.00058 20.1 17.1 0.00058 20.1 17.1 3.0 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 DUF4094 PF13334.6 GAP83793.1 - 0.14 12.6 2.5 0.56 10.7 2.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Mod_r PF07200.13 GAP83793.1 - 2.4 8.2 25.3 0.53 10.4 9.8 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.8 GAP83793.1 - 5.6 7.0 34.0 0.34 11.0 8.0 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding SNARE PF05739.19 GAP83794.1 - 0.24 11.4 0.6 0.61 10.1 0.6 1.7 1 0 0 1 1 1 0 SNARE domain Cellulase PF00150.18 GAP83795.1 - 6e-52 176.8 2.5 7.8e-52 176.4 2.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Steroid_dh PF02544.16 GAP83796.1 - 6.7e-22 78.1 1.4 3.6e-21 75.7 1.4 2.1 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 GAP83796.1 - 2.1e-06 27.4 2.0 3.6e-06 26.7 1.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PhyH PF05721.13 GAP83797.1 - 6.2e-13 49.5 0.1 9.1e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 GAP83797.1 - 8.8e-07 28.1 0.0 1.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP83797.1 - 9.1e-06 25.7 9.4 2e-05 24.6 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MINDY_DUB PF04424.13 GAP83798.1 - 8.9e-25 87.0 0.0 1.6e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase TRF PF08558.10 GAP83799.1 - 1.4e-39 136.1 0.4 2.9e-39 135.1 0.4 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 GAP83799.1 - 5.2e-05 23.4 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP83799.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Aldedh PF00171.22 GAP83800.1 - 4e-184 612.4 0.8 4.5e-184 612.3 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAA_hydrolase PF01557.18 GAP83801.1 - 6.4e-56 189.4 0.0 7.8e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.19 GAP83802.1 - 1.2e-38 133.3 0.0 3.4e-23 82.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 GAP83802.1 - 4.1e-06 26.3 0.1 7.1e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP83802.1 - 0.00052 19.3 0.1 0.00085 18.6 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 GAP83802.1 - 0.00075 18.7 0.0 0.017 14.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAP83802.1 - 0.00078 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP83802.1 - 0.0014 17.8 0.1 0.0021 17.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAP83802.1 - 0.0018 17.1 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 GAP83802.1 - 0.0039 17.4 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAP83802.1 - 0.03 13.5 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 GAP83802.1 - 0.069 13.7 0.1 0.19 12.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP83802.1 - 0.07 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 GAP83802.1 - 0.26 10.3 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyoxalase PF00903.25 GAP83803.1 - 3.1e-09 37.1 3.0 1.3e-08 35.1 1.6 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAP83803.1 - 0.032 14.5 0.1 0.5 10.7 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.18 GAP83804.1 - 7.6e-10 38.3 0.3 1.6e-09 37.2 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP83804.1 - 6.8e-09 35.7 12.3 1.2e-08 34.9 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glycos_transf_1 PF00534.20 GAP83805.1 - 1e-31 109.8 0.0 7e-30 103.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAP83805.1 - 7.2e-17 61.9 0.2 1.1e-16 61.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAP83805.1 - 1.7e-14 54.4 0.1 4.2e-14 53.1 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAP83805.1 - 1.3e-09 38.7 2.6 1.2e-08 35.6 1.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 GAP83805.1 - 0.011 15.8 0.3 4.6 7.2 0.3 2.8 1 1 1 2 2 2 0 ALG11 mannosyltransferase N-terminus IPK PF03770.16 GAP83806.1 - 1.8e-54 184.6 0.0 5.9e-54 182.9 0.0 1.8 2 0 0 2 2 2 1 Inositol polyphosphate kinase Pam17 PF08566.10 GAP83806.1 - 0.017 15.0 0.1 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Tcp11 PF05794.13 GAP83807.1 - 1.6e-96 324.1 1.2 1.3e-95 321.1 0.0 2.3 2 0 0 2 2 2 1 T-complex protein 11 IQ PF00612.27 GAP83807.1 - 0.047 13.5 0.6 0.18 11.7 0.6 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif UPF0242 PF06785.11 GAP83807.1 - 1.5 8.9 9.9 3 7.9 9.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mre11_DNA_bind PF04152.14 GAP83808.1 - 4e-50 170.4 2.2 4e-50 170.4 2.2 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 GAP83808.1 - 2.9e-15 57.3 2.0 5.7e-15 56.4 2.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAP83808.1 - 4.7e-05 23.6 0.1 0.00024 21.3 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2884 PF11101.8 GAP83808.1 - 0.0056 16.2 3.0 0.01 15.4 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) DUF445 PF04286.12 GAP83808.1 - 0.13 12.1 3.0 0.054 13.3 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF445) LicD PF04991.13 GAP83809.1 - 1.2e-22 81.2 2.4 1.3e-11 45.1 0.8 3.2 2 1 1 3 3 3 3 LicD family ADH_N PF08240.12 GAP83810.1 - 3.1e-07 30.3 0.0 9.3e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.21 GAP83810.1 - 0.046 13.8 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit ADH_N_2 PF16884.5 GAP83810.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Fungal_trans PF04082.18 GAP83811.1 - 2.7e-17 62.7 0.6 2.7e-17 62.7 0.6 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAP83811.1 - 1.3e-08 34.8 8.8 5.7e-05 23.3 3.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP83811.1 - 6e-06 26.7 8.2 0.0019 18.9 2.9 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GAP83811.1 - 0.0012 18.6 3.0 0.0037 17.1 3.0 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 GAP83811.1 - 0.0013 19.0 8.0 0.0014 19.0 1.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAP83811.1 - 0.023 15.0 0.6 0.051 13.9 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 GAP83811.1 - 0.066 13.5 4.4 1.1 9.6 4.5 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 GAP83811.1 - 2.4 8.0 9.7 1.2 9.0 0.1 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type CTD_bind PF04818.13 GAP83812.1 - 0.0013 19.5 0.0 0.0038 18.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 GAP83812.1 - 0.0013 19.2 1.4 0.0068 16.9 1.4 2.2 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 zf-C2H2_4 PF13894.6 GAP83812.1 - 0.042 14.7 2.5 1.1 10.3 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 GAP83812.1 - 0.47 10.1 7.7 0.08 12.6 2.2 2.4 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Cu_bind_like PF02298.17 GAP83814.1 - 0.00097 19.1 0.1 0.0024 17.9 0.1 1.6 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 GAP83814.1 - 0.026 15.0 1.9 0.14 12.6 0.6 2.2 1 1 1 2 2 2 0 Copper binding proteins, plastocyanin/azurin family RRM_1 PF00076.22 GAP83815.1 - 5.4e-14 51.8 0.1 9.8e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAP83815.1 - 0.0094 15.9 0.2 0.02 14.9 0.2 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 GAP83815.1 - 0.15 12.1 0.2 0.26 11.3 0.2 1.4 1 0 0 1 1 1 0 RL domain YhzD PF14120.6 GAP83815.1 - 4.8 7.4 6.6 0.7 10.0 0.7 2.5 3 0 0 3 3 3 0 YhzD-like protein TMEM154 PF15102.6 GAP83816.1 - 0.00025 21.0 0.7 0.00035 20.5 0.0 1.6 2 0 0 2 2 2 1 TMEM154 protein family Glycophorin_A PF01102.18 GAP83816.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A Podoplanin PF05808.11 GAP83816.1 - 0.09 12.9 6.4 0.17 12.0 6.3 1.5 1 1 0 1 1 1 0 Podoplanin GRAB PF10375.9 GAP83817.1 - 2.6e-09 36.6 0.1 5e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Spc7 PF08317.11 GAP83817.1 - 5.7e-05 22.1 26.1 5.7e-05 22.1 26.1 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 GAP83817.1 - 0.00015 21.8 58.8 0.12 12.4 13.9 3.3 2 1 1 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 GAP83817.1 - 0.0016 18.1 50.0 0.25 10.9 28.3 2.7 1 1 1 2 2 2 2 Intermediate filament protein NPV_P10 PF05531.12 GAP83817.1 - 0.0025 18.2 17.3 0.055 13.9 0.4 4.3 3 2 1 4 4 4 2 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 GAP83817.1 - 0.003 17.6 27.0 0.043 13.8 7.4 3.5 1 1 1 3 3 3 3 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 GAP83817.1 - 0.0038 17.3 33.8 0.0078 16.3 13.7 4.6 1 1 5 6 6 6 3 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 GAP83817.1 - 0.0066 16.7 12.7 0.0066 16.7 12.7 3.9 1 1 3 4 4 3 2 JNK_SAPK-associated protein-1 Baculo_PEP_C PF04513.12 GAP83817.1 - 0.021 14.9 14.4 0.92 9.6 7.3 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 GAP83817.1 - 0.043 13.3 51.4 0.096 12.1 24.4 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 HALZ PF02183.18 GAP83817.1 - 0.057 13.7 0.9 0.057 13.7 0.9 5.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper Fib_alpha PF08702.10 GAP83817.1 - 0.36 11.0 29.7 0.3 11.3 7.7 3.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family ApoO PF09769.9 GAP83817.1 - 0.47 10.4 7.5 2.1 8.3 0.6 3.5 2 1 1 3 3 3 0 Apolipoprotein O COG5 PF10392.9 GAP83817.1 - 0.49 10.6 20.3 1.7 8.8 5.8 3.6 1 1 1 3 3 3 0 Golgi transport complex subunit 5 TMPIT PF07851.13 GAP83817.1 - 0.66 9.2 31.5 0.68 9.1 4.3 3.2 2 1 1 3 3 3 0 TMPIT-like protein RPW8 PF05659.11 GAP83817.1 - 0.91 9.2 16.7 0.52 10.0 0.5 4.1 1 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 IFT57 PF10498.9 GAP83817.1 - 1.1 8.1 35.8 0.12 11.3 21.3 2.4 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Occludin_ELL PF07303.13 GAP83817.1 - 1.3 9.8 26.9 1.7 9.4 1.9 4.3 1 1 2 4 4 4 0 Occludin homology domain AAA_15 PF13175.6 GAP83817.1 - 2 8.0 19.1 12 5.5 19.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain FPP PF05911.11 GAP83817.1 - 2.1 6.4 45.1 0.019 13.2 21.2 2.6 1 1 1 2 2 1 0 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 GAP83817.1 - 2.1 8.5 67.5 0.45 10.7 27.2 4.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 GAP83817.1 - 2.6 7.3 48.4 0.51 9.6 9.9 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) HOOK PF05622.12 GAP83817.1 - 2.9 5.9 53.7 0.054 11.6 17.9 2.7 1 1 1 2 2 2 0 HOOK protein CEP63 PF17045.5 GAP83817.1 - 3.9 7.3 47.0 0.036 14.0 36.4 2.1 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Lectin_N PF03954.14 GAP83817.1 - 4.4 7.1 23.8 2.1 8.1 2.1 3.5 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain Nup54_57_C PF18570.1 GAP83817.1 - 5.5 6.7 10.4 0.55 9.9 0.1 4.2 4 1 1 5 5 5 0 NUP57/Nup54 C-terminal domain DUF3584 PF12128.8 GAP83817.1 - 5.6 4.3 53.5 0.086 10.3 41.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) GAS PF13851.6 GAP83817.1 - 6.3 6.1 53.3 0.18 11.1 10.7 3.5 1 1 3 4 4 3 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 GAP83817.1 - 8.8 4.4 39.8 19 3.3 12.3 2.9 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA CHD5 PF04420.14 GAP83818.1 - 2.6e-58 196.4 1.2 4.4e-58 195.6 1.2 1.4 1 0 0 1 1 1 1 CHD5-like protein PPTA PF01239.22 GAP83819.1 - 2.9e-07 30.0 3.5 0.017 14.8 0.3 3.7 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat acVLRF1 PF18859.1 GAP83819.1 - 0.1 12.9 0.4 0.66 10.3 0.3 2.1 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor Asp PF00026.23 GAP83820.1 - 3.3e-72 243.6 4.0 4.2e-72 243.2 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP83820.1 - 7.9e-15 55.5 2.3 1.6e-12 48.0 0.8 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAP83820.1 - 0.0011 19.5 0.2 0.14 12.8 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 GAP83820.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 GAP83820.1 - 0.0055 17.2 0.0 0.026 15.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Aa_trans PF01490.18 GAP83821.1 - 3.4e-71 240.1 28.7 4.2e-71 239.8 28.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ras PF00071.22 GAP83823.1 - 6e-56 188.5 0.0 6.9e-56 188.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP83823.1 - 8.2e-22 77.7 0.0 1.2e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP83823.1 - 3.2e-07 30.0 0.0 5.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAP83823.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 GAP83823.1 - 0.067 12.4 0.1 0.62 9.2 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 GAP83823.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region KOW PF00467.29 GAP83824.1 - 0.00048 20.0 0.2 0.0011 18.9 0.2 1.6 1 0 0 1 1 1 1 KOW motif IKI3 PF04762.12 GAP83825.1 - 6e-301 1000.9 0.0 7.3e-301 1000.6 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 GAP83825.1 - 8.4e-08 32.4 1.0 0.18 12.1 0.0 5.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4736 PF15883.5 GAP83825.1 - 0.091 12.5 0.3 0.21 11.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) TPR_1 PF00515.28 GAP83825.1 - 2.4 8.1 4.6 11 6.0 1.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 GAP83825.1 - 2.6 9.1 5.3 6.9e+02 1.4 0.0 5.5 6 0 0 6 6 6 0 WD domain, G-beta repeat TPR_2 PF07719.17 GAP83825.1 - 7.1 7.0 8.2 16 5.9 3.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3984 PF13136.6 GAP83826.1 - 2.1e-60 204.9 17.9 1.2e-59 202.5 17.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) Hpt PF01627.23 GAP83827.1 - 1e-13 51.3 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Hpt domain AKAP7_NLS PF10469.9 GAP83828.1 - 4e-31 108.5 0.0 4.8e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 GAP83828.1 - 0.022 15.0 0.0 8.1 6.7 0.0 3.0 2 1 1 3 3 3 0 LigT like Phosphoesterase HrpB7 PF09486.10 GAP83829.1 - 0.0009 19.7 11.2 0.0018 18.7 11.2 1.5 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 GAP83829.1 - 0.003 16.5 9.7 0.0058 15.5 9.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein IFT57 PF10498.9 GAP83829.1 - 0.028 13.4 5.6 0.049 12.6 5.6 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ADIP PF11559.8 GAP83829.1 - 0.087 12.9 13.8 0.33 11.0 7.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 GAP83829.1 - 0.12 11.7 6.0 0.22 10.8 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2959 PF11172.8 GAP83829.1 - 0.15 12.2 9.9 0.15 12.2 7.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) DUF2508 PF10704.9 GAP83829.1 - 0.17 12.1 5.4 0.72 10.1 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) Golgin_A5 PF09787.9 GAP83829.1 - 0.17 11.3 12.7 0.041 13.4 8.3 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 VPS38 PF17649.1 GAP83829.1 - 0.2 10.5 4.5 0.19 10.6 0.2 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting 38 FlxA PF14282.6 GAP83829.1 - 0.25 11.4 4.3 0.88 9.6 2.0 2.7 1 1 1 2 2 2 0 FlxA-like protein Bap31_Bap29_C PF18035.1 GAP83829.1 - 0.26 11.3 3.5 1.9 8.5 0.2 2.8 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain CENP-F_leu_zip PF10473.9 GAP83829.1 - 0.27 11.2 11.5 0.57 10.2 11.5 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.6 GAP83829.1 - 0.86 10.1 11.1 0.98 9.9 1.0 3.0 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) BRE1 PF08647.11 GAP83829.1 - 0.97 9.6 7.1 0.8 9.8 1.3 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 GAP83829.1 - 1.2 9.3 16.2 18 5.5 16.0 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 GAP83829.1 - 1.2 8.4 7.2 3 7.1 6.7 1.7 1 1 1 2 2 2 0 FAM76 protein TSC22 PF01166.18 GAP83829.1 - 2.6 8.4 5.7 1.7 9.0 0.8 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Cnn_1N PF07989.11 GAP83829.1 - 4.1 7.6 7.6 13 6.1 1.5 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Seryl_tRNA_N PF02403.22 GAP83829.1 - 4.2 7.7 10.7 4.6 7.5 0.3 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 GAP83829.1 - 8.4 6.5 9.9 12 6.0 2.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 GAP83829.1 - 9.3 6.7 13.1 0.5 10.7 1.9 3.3 2 1 1 3 3 3 0 Csm1 N-terminal domain HSP70 PF00012.20 GAP83830.1 - 2e-07 29.6 0.1 1.2e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein FtsA PF14450.6 GAP83830.1 - 0.004 17.6 0.1 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 Cell division protein FtsA Pkinase PF00069.25 GAP83831.1 - 8e-56 189.3 0.0 1.2e-55 188.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP83831.1 - 3.5e-31 108.4 0.0 2.5e-29 102.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 GAP83831.1 - 0.0027 16.7 0.0 0.0053 15.8 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 GAP83831.1 - 0.066 12.2 0.0 0.096 11.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 GAP83831.1 - 0.11 11.9 0.9 0.21 10.9 0.9 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Stc1 PF12898.7 GAP83832.1 - 3.1e-14 53.3 12.2 6.4e-14 52.3 12.2 1.5 1 0 0 1 1 1 1 Stc1 domain dsRBD2 PF17842.1 GAP83832.1 - 0.2 11.9 1.9 0.75 10.0 0.4 2.2 1 1 1 2 2 2 0 Double-stranded RNA binding domain 2 zf-CHY PF05495.12 GAP83832.1 - 2.9 8.4 7.2 1 9.9 4.1 1.8 2 0 0 2 2 2 0 CHY zinc finger DUF4746 PF15928.5 GAP83833.1 - 0.61 9.5 2.1 0.98 8.8 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sugar_tr PF00083.24 GAP83834.1 - 1.5e-93 314.1 16.7 1.9e-93 313.8 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP83834.1 - 1.7e-21 76.5 34.3 5.8e-18 64.9 4.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4601 PF15373.6 GAP83834.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) PLDc_N PF13396.6 GAP83835.1 - 2.3e-12 46.6 1.9 2.3e-12 46.6 1.9 1.9 3 0 0 3 3 3 1 Phospholipase_D-nuclease N-terminal Pox_A14 PF05767.12 GAP83835.1 - 0.041 14.0 0.2 0.066 13.4 0.2 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 MSP1a PF11670.8 GAP83835.1 - 0.045 13.1 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Tetraspanin PF00335.20 GAP83835.1 - 0.096 12.4 2.3 0.14 11.8 2.3 1.3 1 1 0 1 1 1 0 Tetraspanin family Cytochrom_B561 PF03188.16 GAP83835.1 - 0.11 12.7 1.0 2.7 8.1 0.1 2.1 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 DUF3976 PF13121.6 GAP83835.1 - 0.11 12.6 0.4 0.11 12.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3976) DUF3951 PF13131.6 GAP83835.1 - 0.17 12.1 0.1 0.17 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) HisKA_7TM PF16927.5 GAP83835.1 - 0.41 10.7 6.1 0.88 9.6 6.1 1.5 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase DUF2207 PF09972.9 GAP83835.1 - 0.81 8.4 2.6 0.77 8.4 2.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Orai-1 PF07856.12 GAP83835.1 - 2.5 7.7 6.6 2.8 7.6 0.6 1.9 1 1 1 2 2 2 0 Mediator of CRAC channel activity CMAS PF02353.20 GAP83836.1 - 1.5e-17 63.8 0.0 2.3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 GAP83836.1 - 6.3e-13 48.9 0.0 9.6e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP83836.1 - 1.7e-11 44.7 0.1 7.7e-10 39.4 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP83836.1 - 4e-10 40.2 0.0 2.2e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP83836.1 - 4.4e-09 36.3 0.0 4.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAP83836.1 - 1e-08 35.8 0.0 1.1e-07 32.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP83836.1 - 0.0012 18.5 0.0 0.0026 17.3 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.12 GAP83836.1 - 0.0014 18.2 0.1 0.035 13.7 0.0 2.6 3 1 1 4 4 4 1 Methionine biosynthesis protein MetW DOT1 PF08123.13 GAP83836.1 - 0.038 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 GAP83836.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GFO_IDH_MocA PF01408.22 GAP83837.1 - 4e-19 69.6 0.1 6e-19 69.0 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Bac_rhodopsin PF01036.18 GAP83837.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein Aldo_ket_red PF00248.21 GAP83838.1 - 4.8e-14 52.3 0.0 1.3e-13 50.8 0.0 1.6 1 1 1 2 2 2 1 Aldo/keto reductase family Methyltransf_25 PF13649.6 GAP83839.1 - 3.4e-07 30.9 1.7 1.4e-05 25.7 1.7 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP83839.1 - 3.6e-07 30.7 0.1 4.9e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP83839.1 - 4.7e-06 26.5 0.0 3.8e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP83839.1 - 0.0004 20.2 0.0 0.067 13.0 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAP83839.1 - 0.003 18.3 0.0 0.011 16.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Serglycin PF04360.12 GAP83839.1 - 0.03 14.3 0.9 0.03 14.3 0.9 1.8 2 0 0 2 2 2 0 Serglycin MetW PF07021.12 GAP83839.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ubiquitin_2 PF14560.6 GAP83841.1 - 6.3e-22 77.8 0.0 1.1e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 GAP83841.1 - 1.9e-21 75.9 1.0 3.5e-21 75.0 1.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 GAP83841.1 - 0.00017 21.3 0.0 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zf-RING_2 PF13639.6 GAP83842.1 - 2.5e-12 46.9 3.8 4.1e-12 46.2 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAP83842.1 - 5.5e-10 38.8 1.5 1.2e-09 37.7 1.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAP83842.1 - 1.1e-06 28.4 2.2 1.9e-06 27.7 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP83842.1 - 1.6e-06 27.9 3.9 2.7e-06 27.1 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAP83842.1 - 7.6e-06 26.1 4.2 2.1e-05 24.7 4.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAP83842.1 - 2.8e-05 23.9 3.6 5.7e-05 22.9 3.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAP83842.1 - 3.3e-05 23.8 1.2 6e-05 22.9 1.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAP83842.1 - 0.0054 16.6 1.4 0.0097 15.7 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAP83842.1 - 0.0077 16.3 1.1 0.015 15.3 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 GAP83842.1 - 0.023 14.7 5.2 0.051 13.6 5.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 GAP83842.1 - 0.065 13.0 2.5 0.11 12.3 2.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 GAP83842.1 - 0.11 12.8 1.6 0.18 12.1 1.6 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 GAP83842.1 - 0.32 10.9 2.4 0.63 10.0 2.4 1.5 1 0 0 1 1 1 0 PHD-finger CCDC53 PF10152.9 GAP83842.1 - 2.8 8.4 6.2 1.1 9.7 2.9 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Prok-RING_1 PF14446.6 GAP83842.1 - 3.1 7.8 5.3 10 6.1 3.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Glyco_hydro_cc PF11790.8 GAP83843.1 - 2.6e-53 181.0 1.4 3.8e-53 180.5 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Zn_clus PF00172.18 GAP83844.1 - 5.6e-08 32.8 9.1 9.8e-08 32.0 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAP83844.1 - 0.00059 18.8 0.2 0.00095 18.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4614 PF15391.6 GAP83845.1 - 0.11 12.5 10.8 0.85 9.6 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) SR-25 PF10500.9 GAP83845.1 - 0.34 10.5 19.0 0.22 11.1 9.7 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 GAP83845.1 - 0.98 9.8 20.4 8.5 6.8 16.0 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain FAM104 PF15434.6 GAP83845.1 - 1.2 9.7 8.7 0.73 10.4 4.9 2.2 2 0 0 2 2 2 0 Family 104 CDK2AP PF09806.9 GAP83845.1 - 1.2 9.1 7.9 0.17 12.0 2.8 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein TFIIF_alpha PF05793.12 GAP83845.1 - 4 5.9 4.6 6.7 5.2 4.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IMUP PF15761.5 GAP83845.1 - 5.8 7.7 19.6 10 6.9 1.1 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein RSRP PF17069.5 GAP83845.1 - 9.8 5.6 24.0 1.9 8.0 10.6 2.1 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 BING4CT PF08149.11 GAP83846.1 - 1.7e-34 117.4 0.1 1.1e-32 111.7 0.0 3.5 4 0 0 4 4 4 1 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 GAP83846.1 - 1.7e-05 25.0 2.2 4.9 7.5 0.0 5.4 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 GAP83846.1 - 0.00017 20.8 0.0 0.00036 19.7 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 GAP83846.1 - 0.15 13.0 2.2 72 4.5 1.8 4.0 1 1 1 2 2 2 0 WD domain, G-beta repeat RIBIOP_C PF04950.12 GAP83847.1 - 8.6e-110 366.8 0.0 1.2e-109 366.2 0.0 1.2 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAP83847.1 - 2.2e-17 62.9 0.0 5.8e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.19 GAP83848.1 - 4.4e-34 117.6 0.0 5.7e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 GAP83848.1 - 1.4e-05 24.3 1.2 9.4e-05 21.5 1.2 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 GAP83848.1 - 0.0016 19.0 0.0 0.0023 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 GAP83848.1 - 0.037 14.1 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 GAP83848.1 - 0.1 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain zf-HIT PF04438.16 GAP83850.1 - 1.9e-08 34.0 8.8 2.9e-08 33.5 8.8 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 GAP83850.1 - 0.042 13.9 5.1 0.065 13.3 5.1 1.3 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.24 GAP83850.1 - 0.17 12.1 4.7 0.28 11.4 4.7 1.3 1 0 0 1 1 1 0 B-box zinc finger Nfu_N PF08712.11 GAP83851.1 - 4e-28 97.3 0.0 1.1e-27 95.8 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 GAP83851.1 - 8.2e-27 93.2 0.1 1.4e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.12 GAP83852.1 - 7e-28 96.8 0.9 7e-28 96.8 0.9 1.7 2 0 0 2 2 2 1 PSP1 C-terminal conserved region DUF5094 PF17015.5 GAP83852.1 - 0.098 12.8 1.1 0.19 11.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) DUF3881 PF12997.7 GAP83852.1 - 0.23 10.7 1.3 0.36 10.0 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) FRB_dom PF08771.11 GAP83853.1 - 0.14 12.6 1.7 0.2 12.1 0.5 1.9 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain F_actin_bund_C PF18060.1 GAP83853.1 - 4.2 7.6 10.4 0.67 10.1 4.6 2.5 2 1 0 2 2 2 0 F actin bundling C terminal Ribosomal_L15e PF00827.17 GAP83854.1 - 1.1e-89 299.3 9.7 1.3e-89 299.0 9.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 PUF PF00806.19 GAP83855.1 - 5.5e-58 189.5 11.2 3.9e-08 32.5 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RNA_pol_Rpb2_6 PF00562.28 GAP83856.1 - 6.8e-121 404.0 0.0 1e-120 403.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAP83856.1 - 6.5e-50 169.5 0.1 1.1e-49 168.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 GAP83856.1 - 8.4e-33 112.6 0.5 2e-32 111.4 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 GAP83856.1 - 5.3e-27 94.7 0.0 1.3e-26 93.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 GAP83856.1 - 4.7e-22 78.1 0.0 1.3e-21 76.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 GAP83856.1 - 2.3e-20 72.5 0.0 4.8e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 GAP83856.1 - 6.8e-12 45.8 0.1 2.5e-11 43.9 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Rad51 PF08423.11 GAP83857.1 - 2.2e-41 141.8 0.0 2.8e-39 134.9 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 GAP83857.1 - 2.3e-07 30.6 0.3 1.2e-06 28.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain RecA PF00154.21 GAP83857.1 - 2.4e-06 27.2 0.0 4.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 GAP83857.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.6 GAP83857.1 - 0.0023 18.4 0.1 0.0065 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 GAP83857.1 - 0.018 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAP83857.1 - 0.052 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TrbC PF04956.13 GAP83858.1 - 0.051 13.8 0.7 0.093 13.0 0.0 1.7 2 0 0 2 2 2 0 TrbC/VIRB2 family Secretin_N_2 PF07655.13 GAP83858.1 - 0.7 10.5 13.1 1.4 9.5 13.1 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain S6OS1 PF15676.5 GAP83858.1 - 0.81 8.1 4.5 1.1 7.6 4.5 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Carn_acyltransf PF00755.20 GAP83859.1 - 5.5e-207 689.0 0.0 1.5e-206 687.5 0.0 1.6 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase MMU163 PF17119.5 GAP83861.1 - 2.4e-77 259.4 7.3 7.8e-57 192.3 1.6 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Tom5 PF10642.9 GAP83861.1 - 0.12 12.4 0.3 0.38 10.8 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Ras PF00071.22 GAP83862.1 - 1.7e-65 219.5 0.5 2e-65 219.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP83862.1 - 7.1e-36 123.1 0.1 1.3e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP83862.1 - 3.5e-16 59.2 0.1 4.2e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAP83862.1 - 2.7e-05 24.2 0.0 9.4e-05 22.5 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP83862.1 - 3.8e-05 23.6 0.2 0.13 12.1 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 GAP83862.1 - 8.9e-05 22.1 0.4 0.00024 20.7 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAP83862.1 - 0.00027 20.4 0.1 0.00034 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAP83862.1 - 0.00045 19.7 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 GAP83862.1 - 0.0027 18.1 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 GAP83862.1 - 0.0043 16.6 0.0 0.025 14.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 GAP83862.1 - 0.0077 16.6 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP83862.1 - 0.035 14.4 0.0 0.068 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAP83862.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 GAP83862.1 - 0.083 12.9 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.18 GAP83862.1 - 0.085 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 GAP83862.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 GAP83862.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 GAP83862.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 GAP83862.1 - 0.11 12.2 0.1 0.68 9.7 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation IBR PF01485.21 GAP83864.1 - 1.9e-13 50.4 38.0 5.5e-08 32.9 4.9 4.1 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 GAP83864.1 - 0.014 15.2 1.8 0.014 15.2 1.8 5.0 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP83864.1 - 0.02 14.7 2.2 0.02 14.7 2.2 4.3 5 1 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Pox_vIL-18BP PF05566.12 GAP83864.1 - 0.047 13.9 0.1 0.22 11.8 0.1 2.1 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein zf_UBZ PF18439.1 GAP83864.1 - 0.21 11.2 6.1 1.4 8.5 0.1 4.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF1563 PF07599.11 GAP83864.1 - 0.45 10.6 2.3 0.84 9.8 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) adh_short PF00106.25 GAP83865.1 - 9.2e-19 67.7 0.0 2e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP83865.1 - 3.5e-07 30.0 0.1 7.8e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP83865.1 - 1.5e-05 25.0 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP83865.1 - 0.17 11.3 0.1 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family WD40 PF00400.32 GAP83866.1 - 1.1e-14 54.6 16.2 0.011 16.6 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP83866.1 - 0.0051 17.1 0.2 7.7 6.9 0.0 3.8 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 GAP83866.1 - 0.0091 15.0 0.2 1.2 8.0 0.0 2.4 2 0 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 GAP83866.1 - 0.011 15.1 0.1 0.73 9.1 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain PQQ_3 PF13570.6 GAP83866.1 - 0.014 15.8 0.3 1.2 9.7 0.0 3.8 4 1 0 4 4 4 0 PQQ-like domain DUF627 PF04781.12 GAP83866.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Nup160 PF11715.8 GAP83866.1 - 0.18 10.4 2.9 2.7 6.5 0.1 3.6 2 1 3 5 5 5 0 Nucleoporin Nup120/160 Mcl1_mid PF12341.8 GAP83867.1 - 6e-100 334.4 0.0 1.5e-97 326.6 0.0 2.7 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 GAP83867.1 - 1.7e-22 79.3 1.5 9.7e-08 32.6 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP83867.1 - 4.9e-16 58.8 0.0 6.5e-05 23.2 0.1 6.9 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAP83867.1 - 0.00029 20.8 0.0 0.0051 16.7 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 GAP83867.1 - 0.00089 18.4 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region DNA_pol_alpha_N PF12254.8 GAP83867.1 - 0.0012 18.8 0.3 0.0041 17.2 0.3 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal PD40 PF07676.12 GAP83867.1 - 0.0026 17.6 0.1 20 5.3 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 GAP83867.1 - 0.0057 14.7 0.1 0.011 13.8 0.1 1.4 1 0 0 1 1 1 1 IKI3 family Frtz PF11768.8 GAP83867.1 - 0.016 13.5 0.0 0.5 8.6 0.0 2.4 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 GAP83867.1 - 0.12 11.7 0.0 12 5.1 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain DUF1664 PF07889.12 GAP83869.1 - 0.13 12.3 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Abhydrolase_3 PF07859.13 GAP83870.1 - 5.4e-36 124.4 0.0 1.5e-25 90.3 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP83870.1 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Lipase_3 PF01764.25 GAP83870.1 - 0.024 14.5 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Aminotran_3 PF00202.21 GAP83871.1 - 2e-111 372.5 0.0 2.6e-111 372.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Pyridoxal_deC PF00282.19 GAP83872.1 - 5.3e-59 199.8 0.0 7.4e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAP83872.1 - 0.00031 19.8 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 GAP83872.1 - 0.03 13.1 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Fungal_trans PF04082.18 GAP83875.1 - 2.9e-23 82.3 0.0 4.9e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain APC_N_CC PF16689.5 GAP83875.1 - 0.36 10.9 1.1 0.71 10.0 1.1 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain RabGAP-TBC PF00566.18 GAP83876.1 - 8e-50 169.5 0.0 1.6e-49 168.5 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Porphobil_deamC PF03900.15 GAP83876.1 - 0.14 12.5 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain Fungal_trans PF04082.18 GAP83877.1 - 1.5e-24 86.5 0.0 2.6e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP83877.1 - 2.1e-05 24.5 11.1 3.7e-05 23.7 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.8 GAP83877.1 - 9.2e-05 22.4 3.4 0.00018 21.4 3.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) BSP_II PF05432.11 GAP83877.1 - 0.021 14.5 4.8 0.033 13.9 4.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.6 GAP83877.1 - 0.041 13.5 1.4 0.073 12.7 1.4 1.3 1 0 0 1 1 1 0 FAM176 family PBP_sp32 PF07222.12 GAP83877.1 - 0.1 12.0 5.3 0.18 11.2 5.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Androgen_recep PF02166.16 GAP83877.1 - 0.16 10.8 13.2 0.074 11.9 6.2 2.3 2 0 0 2 2 2 0 Androgen receptor Ctr PF04145.15 GAP83877.1 - 0.24 12.0 0.6 0.63 10.6 0.4 1.7 2 0 0 2 2 2 0 Ctr copper transporter family BRF1 PF07741.13 GAP83877.1 - 0.54 10.6 2.3 1.3 9.4 2.3 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4834 PF16118.5 GAP83877.1 - 0.6 11.1 3.2 1.5 9.8 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SSP160 PF06933.11 GAP83877.1 - 1.8 6.7 11.8 2.7 6.1 11.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Activator_LAG-3 PF11498.8 GAP83877.1 - 8.5 5.2 14.2 14 4.5 14.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 adh_short_C2 PF13561.6 GAP83878.1 - 4.3e-51 173.7 1.0 5.3e-51 173.4 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP83878.1 - 8.2e-40 136.3 0.9 1.1e-39 136.0 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP83878.1 - 1.1e-15 58.0 0.2 1.5e-15 57.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP83878.1 - 1.8e-07 30.9 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAP83878.1 - 0.0021 17.3 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAP83878.1 - 0.0057 16.1 0.0 0.0076 15.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAP83878.1 - 0.052 12.5 0.1 0.065 12.2 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PRK PF00485.18 GAP83879.1 - 3.1e-06 27.1 0.0 4.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 GAP83879.1 - 6.4e-05 23.4 0.0 8.7e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 GAP83879.1 - 0.00014 22.0 0.2 0.00066 19.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAP83879.1 - 0.00024 20.4 0.0 0.00037 19.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain T2SSE PF00437.20 GAP83879.1 - 0.00041 19.5 0.1 0.00092 18.3 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 GAP83879.1 - 0.00088 19.7 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAP83879.1 - 0.0017 18.9 0.0 0.0036 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAP83879.1 - 0.0024 17.2 0.0 0.0059 15.9 0.0 1.6 2 0 0 2 2 1 1 Zeta toxin AAA_19 PF13245.6 GAP83879.1 - 0.0032 17.8 0.0 0.0037 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAP83879.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 GAP83879.1 - 0.0072 16.6 0.1 0.022 15.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAP83879.1 - 0.0085 16.4 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain CobU PF02283.16 GAP83879.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase Cytidylate_kin PF02224.18 GAP83879.1 - 0.012 15.3 0.1 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_30 PF13604.6 GAP83879.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAP83879.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 GAP83879.1 - 0.018 14.8 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAP83879.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 GAP83879.1 - 0.026 14.5 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 GAP83879.1 - 0.031 13.8 0.1 0.066 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 GAP83879.1 - 0.033 13.4 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.20 GAP83879.1 - 0.035 14.0 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 GAP83879.1 - 0.036 14.5 0.0 0.055 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 GAP83879.1 - 0.037 13.4 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 GAP83879.1 - 0.044 14.3 0.0 0.048 14.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 GAP83879.1 - 0.046 13.6 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain CoaE PF01121.20 GAP83879.1 - 0.054 13.2 0.1 2.7 7.6 0.1 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_24 PF13479.6 GAP83879.1 - 0.084 12.6 0.0 0.27 10.9 0.0 1.7 1 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAP83879.1 - 0.1 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.10 GAP83879.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Rad17 PF03215.15 GAP83879.1 - 0.15 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_PrkA PF08298.11 GAP83879.1 - 0.16 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain Thymidylate_kin PF02223.17 GAP83879.1 - 0.16 11.6 0.0 7.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase MeaB PF03308.16 GAP83879.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 GAP83879.1 - 0.19 11.8 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase adh_short_C2 PF13561.6 GAP83880.1 - 1.7e-58 197.9 4.6 2e-58 197.7 4.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP83880.1 - 1.4e-42 145.4 3.5 1.8e-42 145.0 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP83880.1 - 1.3e-14 54.5 0.9 1.7e-14 54.1 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP83880.1 - 0.0045 16.5 0.3 0.06 12.8 0.2 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 GAP83880.1 - 0.015 15.4 1.0 0.04 14.0 0.9 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 GAP83880.1 - 0.024 14.9 0.3 0.037 14.3 0.3 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Fibrillin_U_N PF18193.1 GAP83881.1 - 0.033 14.3 0.5 0.079 13.1 0.5 1.7 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain PHD PF00628.29 GAP83881.1 - 2.5 8.1 10.9 1.6 8.7 2.5 2.8 1 1 1 2 2 2 0 PHD-finger P21-Arc PF04062.14 GAP83883.1 - 4.7e-71 238.4 0.0 5.3e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.18 GAP83883.1 - 0.082 13.0 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Pancreatic hormone peptide Gcd10p PF04189.13 GAP83884.1 - 3.7e-120 400.6 0.0 5e-120 400.2 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family HopJ PF08888.11 GAP83884.1 - 0.16 12.2 0.1 0.32 11.2 0.1 1.4 1 0 0 1 1 1 0 HopJ type III effector protein Band_7 PF01145.25 GAP83885.1 - 4.2e-15 56.2 0.1 4.2e-15 56.2 0.1 2.9 2 1 1 3 3 3 1 SPFH domain / Band 7 family Flot PF15975.5 GAP83885.1 - 0.018 15.2 6.3 0.018 15.2 6.3 3.7 2 1 1 3 3 3 0 Flotillin Spc7 PF08317.11 GAP83887.1 - 0.00093 18.2 3.7 0.0015 17.5 3.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF812 PF05667.11 GAP83887.1 - 0.0033 16.4 1.5 0.0047 15.9 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GAS PF13851.6 GAP83887.1 - 0.02 14.3 5.0 0.042 13.2 5.0 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Vps5 PF09325.10 GAP83887.1 - 0.02 14.5 1.3 0.69 9.4 1.2 2.3 2 0 0 2 2 2 0 Vps5 C terminal like DUF4201 PF13870.6 GAP83887.1 - 0.029 14.1 2.4 0.054 13.2 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF724 PF05266.14 GAP83887.1 - 0.069 13.0 3.7 0.12 12.2 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ERM PF00769.19 GAP83887.1 - 0.072 12.9 5.4 0.14 12.0 5.4 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family V-SNARE_C PF12352.8 GAP83887.1 - 0.078 13.3 0.4 0.3 11.4 0.1 2.2 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF1664 PF07889.12 GAP83887.1 - 0.098 12.7 3.9 0.46 10.5 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SprA_N PF14349.6 GAP83887.1 - 0.15 10.9 0.3 0.21 10.4 0.3 1.1 1 0 0 1 1 1 0 Motility related/secretion protein Vps51 PF08700.11 GAP83887.1 - 0.15 12.1 3.6 0.25 11.4 0.9 2.7 3 0 0 3 3 3 0 Vps51/Vps67 I_LWEQ PF01608.17 GAP83887.1 - 0.18 12.1 4.2 0.75 10.0 0.6 2.3 1 1 1 2 2 2 0 I/LWEQ domain Vps53_N PF04100.12 GAP83887.1 - 0.19 10.6 2.4 0.34 9.8 2.4 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal APG6_N PF17675.1 GAP83887.1 - 0.29 11.7 1.8 0.6 10.6 1.8 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Fib_alpha PF08702.10 GAP83887.1 - 0.32 11.2 4.0 7.7 6.7 1.2 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 GAP83887.1 - 0.43 11.0 10.6 0.68 10.4 1.7 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 GAP83887.1 - 0.68 9.9 5.4 0.91 9.5 2.7 2.2 2 0 0 2 2 2 0 Laminin Domain II XhlA PF10779.9 GAP83887.1 - 1.4 9.2 6.4 0.33 11.2 2.0 2.3 2 1 0 2 2 2 0 Haemolysin XhlA ATG16 PF08614.11 GAP83887.1 - 2.5 8.3 7.7 0.23 11.6 2.6 1.9 2 0 0 2 2 1 0 Autophagy protein 16 (ATG16) Rep-A_N PF04057.12 GAP83888.1 - 0.0019 18.2 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain BRCA-2_OB1 PF09103.10 GAP83888.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Glyco_hydro_61 PF03443.14 GAP83889.1 - 3.1e-06 27.3 0.1 7.5e-05 22.8 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 LPG_synthase_TM PF03706.13 GAP83890.1 - 0.095 12.2 0.1 0.092 12.3 0.1 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region SARAF PF06682.12 GAP83891.1 - 0.00014 21.6 0.7 0.00014 21.6 0.7 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CYYR1 PF10873.8 GAP83891.1 - 0.00035 21.0 1.0 0.00053 20.5 0.2 1.6 1 1 1 2 2 2 1 Cysteine and tyrosine-rich protein 1 RCR PF12273.8 GAP83891.1 - 0.0018 18.9 1.1 0.0027 18.3 1.1 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 GAP83891.1 - 0.0049 17.7 0.0 0.0077 17.1 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 GAP83891.1 - 0.0055 17.0 0.2 0.0071 16.6 0.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Peptidase_M56 PF05569.11 GAP83891.1 - 0.0069 15.6 0.0 0.0081 15.4 0.0 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 OATP PF03137.20 GAP83891.1 - 0.0089 14.4 0.1 0.01 14.2 0.1 1.0 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MLANA PF14991.6 GAP83891.1 - 0.014 15.6 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A DUF2062 PF09835.9 GAP83891.1 - 0.015 15.2 0.1 0.03 14.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Phage_holin_2_4 PF16082.5 GAP83891.1 - 0.016 14.9 0.2 0.027 14.2 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF2207 PF09972.9 GAP83891.1 - 0.03 13.1 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM100 PF16311.5 GAP83891.1 - 0.031 13.9 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 SNARE_assoc PF09335.11 GAP83891.1 - 0.035 14.6 0.0 0.047 14.2 0.0 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF3413 PF11893.8 GAP83891.1 - 0.043 13.0 0.0 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) LapA_dom PF06305.11 GAP83891.1 - 0.047 13.5 1.5 0.075 12.9 1.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Vpu PF00558.19 GAP83891.1 - 0.054 13.3 0.1 0.086 12.6 0.1 1.3 1 0 0 1 1 1 0 Vpu protein DUF2244 PF10003.9 GAP83891.1 - 0.067 12.9 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Saf_2TM PF18303.1 GAP83891.1 - 0.069 12.7 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Herpes_gE PF02480.16 GAP83891.1 - 0.077 11.7 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3318 PF11780.8 GAP83891.1 - 0.099 12.6 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) DUF4381 PF14316.6 GAP83891.1 - 0.14 12.4 2.0 0.19 12.0 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Stevor PF17410.2 GAP83891.1 - 0.19 11.3 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4834 PF16118.5 GAP83891.1 - 2.2 9.3 3.6 1.1 10.2 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) p450 PF00067.22 GAP83892.1 - 1.4e-82 277.9 0.0 1.7e-82 277.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UL2 PF08196.11 GAP83893.1 - 0.002 18.1 0.3 0.002 18.1 0.3 1.9 1 1 1 2 2 2 1 UL2 protein Sulf_transp PF04143.14 GAP83893.1 - 0.026 14.1 3.5 0.03 13.9 3.5 1.0 1 0 0 1 1 1 0 Sulphur transport Virul_Fac PF10139.9 GAP83893.1 - 0.15 10.2 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor Sigma_reg_N PF13800.6 GAP83893.1 - 0.81 10.0 5.2 9.9 6.5 0.8 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal T2SSF PF00482.23 GAP83893.1 - 1.4 8.9 7.0 3.1 7.8 1.2 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F SLATT_5 PF18160.1 GAP83893.1 - 1.6 8.0 6.9 12 5.2 6.9 1.9 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 E1-E2_ATPase PF00122.20 GAP83893.1 - 2.4 7.7 7.0 12 5.4 6.5 1.9 1 1 1 2 2 2 0 E1-E2 ATPase DUF5383 PF17355.2 GAP83893.1 - 3.5 8.0 4.5 19 5.6 1.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Amnionless PF14828.6 GAP83893.1 - 7 5.4 5.7 5.8 5.6 0.6 1.9 1 1 1 2 2 2 0 Amnionless Glyco_hydro_61 PF03443.14 GAP83894.1 - 2.9e-59 200.4 0.3 3.6e-59 200.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3425 PF11905.8 GAP83895.1 - 4.8e-21 75.0 0.1 9.7e-21 74.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAP83895.1 - 0.024 14.7 4.2 0.046 13.8 4.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor FAD_binding_4 PF01565.23 GAP83896.1 - 6.1e-19 68.1 3.9 1.1e-18 67.3 3.4 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP83896.1 - 0.0041 17.2 0.0 0.0095 16.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 GAP83897.1 - 6.7e-48 163.4 35.8 6.7e-48 163.4 35.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP83897.1 - 1.7e-14 53.6 7.3 1.7e-14 53.6 7.3 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 GAP83897.1 - 2.4 6.3 13.1 0.015 13.6 1.4 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Cwf_Cwc_15 PF04889.12 GAP83898.1 - 0.077 12.7 3.9 0.1 12.3 3.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein KASH_CCD PF14662.6 GAP83899.1 - 0.0033 17.3 5.6 0.087 12.6 0.4 2.1 1 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH PKcGMP_CC PF16808.5 GAP83899.1 - 0.0088 15.9 0.7 0.0088 15.9 0.7 2.0 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase ERM PF00769.19 GAP83899.1 - 0.1 12.4 9.2 0.14 11.9 9.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF641 PF04859.12 GAP83899.1 - 0.11 12.8 2.0 0.58 10.5 2.0 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Atg14 PF10186.9 GAP83899.1 - 0.16 11.0 6.8 0.2 10.7 6.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 GAP83899.1 - 0.25 11.7 4.8 2.6 8.5 0.2 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain Phlebovirus_NSM PF07246.11 GAP83899.1 - 0.75 9.1 2.4 0.95 8.8 2.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FUSC PF04632.12 GAP83899.1 - 6.6 5.1 15.9 8.1 4.8 15.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family MPS2 PF17060.5 GAP83900.1 - 0.00049 19.5 5.7 0.0035 16.7 5.7 1.9 1 1 0 1 1 1 1 Monopolar spindle protein 2 FPP PF05911.11 GAP83900.1 - 0.0015 16.8 0.7 0.0015 16.8 0.7 1.7 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 GAP83900.1 - 0.0034 16.3 4.8 0.0034 16.3 4.8 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein ATG16 PF08614.11 GAP83900.1 - 0.0064 16.7 11.2 0.015 15.5 4.1 3.1 2 2 1 3 3 2 2 Autophagy protein 16 (ATG16) DUF4472 PF14739.6 GAP83900.1 - 0.09 13.5 0.7 0.09 13.5 0.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) DUF1664 PF07889.12 GAP83900.1 - 0.099 12.7 0.9 1.2 9.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 GAP83900.1 - 0.14 12.3 8.5 0.32 11.2 8.5 1.6 1 0 0 1 1 1 0 Tropomyosin like BicD PF09730.9 GAP83900.1 - 0.16 10.4 11.3 0.25 9.7 11.3 1.3 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Atg14 PF10186.9 GAP83900.1 - 0.3 10.1 10.6 0.57 9.2 10.4 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 GAP83900.1 - 0.43 10.6 6.5 9.3 6.3 0.0 2.6 2 1 1 3 3 3 0 Laminin Domain II UPF0242 PF06785.11 GAP83900.1 - 3.5 7.7 9.8 4.7 7.3 5.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 GAP83900.1 - 3.8 7.9 8.9 0.34 11.2 2.2 2.4 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) DUF913 PF06025.12 GAP83900.1 - 7.3 5.5 7.5 11 4.9 0.3 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FAM76 PF16046.5 GAP83900.1 - 8.6 5.6 14.7 0.73 9.1 1.7 2.2 2 0 0 2 2 2 0 FAM76 protein Exonuc_VII_L PF02601.15 GAP83900.1 - 8.9 5.8 11.6 0.22 11.0 3.4 1.9 1 1 0 2 2 2 0 Exonuclease VII, large subunit DBR1 PF05011.13 GAP83902.1 - 9e-20 71.5 0.0 1.6e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 GAP83902.1 - 2e-06 28.5 0.4 3.1e-06 27.8 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Skp1_POZ PF03931.15 GAP83903.1 - 4.1e-10 39.7 0.0 5.5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ras PF00071.22 GAP83904.1 - 1.4e-47 161.3 0.0 1.9e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP83904.1 - 2.6e-20 72.8 0.0 4.8e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP83904.1 - 1.4e-05 24.6 0.0 4e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 GAP83904.1 - 0.02 14.4 0.1 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 GAP83904.1 - 0.078 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DASH_Dad1 PF08649.10 GAP83905.1 - 1.2e-26 92.6 2.4 1.5e-26 92.3 2.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 GAP83905.1 - 0.04 13.9 0.2 0.06 13.3 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 CK2S PF15011.6 GAP83905.1 - 0.055 13.4 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate Metallophos PF00149.28 GAP83906.1 - 7.4e-33 114.8 0.0 8.4e-31 108.1 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 GAP83906.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Smg4_UPF3 PF03467.15 GAP83907.1 - 1.4e-40 139.1 0.0 1.4e-40 139.1 0.0 2.8 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 GAP83907.1 - 1e-05 25.2 0.1 0.00011 21.9 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A PF15396.6 GAP83908.1 - 0.056 13.5 0.9 0.094 12.7 0.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PI3K_1B_p101 PF10486.9 GAP83908.1 - 0.063 11.0 2.0 0.088 10.6 2.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PPP4R2 PF09184.11 GAP83908.1 - 0.28 10.8 7.4 0.42 10.2 7.4 1.2 1 0 0 1 1 1 0 PPP4R2 PBP1_TM PF14812.6 GAP83908.1 - 1.4 9.4 7.0 0.25 11.7 2.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_19 PF14559.6 GAP83909.1 - 0.022 15.3 0.3 0.11 13.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-ZPR1 PF03367.13 GAP83910.1 - 3.5e-113 374.7 0.0 2e-57 193.5 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 GAP83910.1 - 0.16 12.0 2.2 2.8 8.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbons DnaJ_CXXCXGXG PF00684.19 GAP83910.1 - 0.71 10.3 3.5 12 6.3 0.1 2.7 2 1 1 3 3 3 0 DnaJ central domain Rpr2 PF04032.16 GAP83911.1 - 1.2e-12 47.9 0.6 1.2e-12 47.9 0.6 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain CAP_N PF01213.19 GAP83911.1 - 0.058 12.9 6.2 0.1 12.1 6.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 GAP83911.1 - 0.14 12.2 6.2 0.21 11.6 6.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Abhydrolase_6 PF12697.7 GAP83912.1 - 2.2e-17 64.4 8.7 4e-17 63.6 8.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP83912.1 - 4.7e-15 55.5 2.0 1.6e-14 53.7 1.1 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP83912.1 - 1.3e-14 54.5 0.7 2.3e-14 53.7 0.7 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP83912.1 - 0.00066 19.2 0.9 0.063 12.7 0.6 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 GAP83912.1 - 0.0033 17.6 0.3 0.0056 16.8 0.3 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 GAP83912.1 - 0.0092 15.7 1.1 0.072 12.8 1.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 GAP83912.1 - 0.051 13.4 0.1 0.082 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF3425 PF11905.8 GAP83914.1 - 1.7e-14 53.8 0.0 3.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Amidohydro_1 PF01979.20 GAP83915.1 - 6.4e-24 84.9 0.0 7.7e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAP83915.1 - 2.2e-06 27.4 1.2 6.5e-06 25.9 1.2 1.6 1 1 0 1 1 1 1 Amidohydrolase family RRM_1 PF00076.22 GAP83916.1 - 3.3e-23 81.3 0.1 2.9e-14 52.6 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAP83916.1 - 0.0034 17.0 0.0 0.59 9.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAP83916.1 - 0.0036 17.1 0.0 0.82 9.6 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif DbpA PF03880.15 GAP83916.1 - 0.0094 15.9 0.0 5.1 7.2 0.0 2.4 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_9 PF18444.1 GAP83916.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif MFS_1 PF07690.16 GAP83917.1 - 1.1e-30 106.8 44.8 1.1e-30 106.8 44.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP83917.1 - 3.7e-13 48.8 16.9 6.5e-13 48.0 15.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.8 GAP83917.1 - 0.0019 16.9 8.7 0.0019 16.9 8.7 2.3 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like DUF3574 PF12098.8 GAP83918.1 - 0.039 13.7 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) DUF4398 PF14346.6 GAP83919.1 - 0.02 15.5 2.8 0.022 15.3 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) PAN_4 PF14295.6 GAP83920.1 - 5.6e-05 23.0 0.7 0.0001 22.1 0.7 1.4 1 0 0 1 1 1 1 PAN domain 2Fe-2S_thioredx PF01257.19 GAP83921.1 - 0.22 11.4 0.1 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin SET PF00856.28 GAP83922.1 - 8.1e-07 29.6 0.1 3e-06 27.7 0.1 1.7 1 1 0 1 1 1 1 SET domain Phage_holin_2_2 PF10746.9 GAP83924.1 - 9.6 6.0 6.8 0.83 9.4 0.8 2.4 2 1 1 3 3 3 0 Phage holin T7 family, holin superfamily II DUF3328 PF11807.8 GAP83925.1 - 2.4e-21 76.5 10.3 6.2e-21 75.2 10.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) ROKNT PF08067.11 GAP83926.1 - 0.002 18.4 13.1 1.9 8.9 0.8 4.4 1 1 5 6 6 6 6 ROKNT (NUC014) domain Lpp-LpqN PF10738.9 GAP83926.1 - 0.13 11.7 3.9 13 5.2 0.1 2.9 1 1 3 4 4 4 0 Probable lipoprotein LpqN Polbeta PF18765.1 GAP83926.1 - 1.4 9.0 22.0 1.3e+02 2.7 7.1 4.8 1 1 1 2 2 2 0 Polymerase beta, Nucleotidyltransferase DUF4398 PF14346.6 GAP83926.1 - 6.5 7.5 12.3 1.4e+02 3.2 10.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) DUF3328 PF11807.8 GAP83927.1 - 3e-21 76.2 0.0 7.1e-20 71.7 0.1 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) FAD_binding_4 PF01565.23 GAP83928.1 - 7e-25 87.4 2.5 7e-25 87.4 2.5 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAP83928.1 - 0.001 19.1 0.4 0.0029 17.7 0.4 1.8 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 GAP83929.1 - 6.2e-43 147.1 52.8 6.2e-43 147.1 52.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP83929.1 - 1e-09 37.4 16.4 4.7e-09 35.2 11.2 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Methyltransf_33 PF10017.9 GAP83930.1 - 2.8e-79 266.5 0.0 3.3e-79 266.3 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent SRCR PF00530.18 GAP83930.1 - 0.065 13.7 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain FERM_f0 PF16511.5 GAP83930.1 - 0.12 12.7 0.1 5.1 7.5 0.0 2.3 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM AMP-binding PF00501.28 GAP83931.1 - 0 1112.3 0.0 5.2e-74 249.3 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 GAP83931.1 - 7.8e-218 723.7 0.0 2.9e-39 135.0 0.0 6.5 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.25 GAP83931.1 - 4.8e-59 196.6 3.8 2.1e-12 47.2 0.0 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAP83931.1 - 2.3e-09 38.1 0.0 0.12 13.4 0.0 5.8 5 0 0 5 5 5 2 AMP-binding enzyme C-terminal domain adh_short PF00106.25 GAP83932.1 - 1.4e-10 41.0 0.0 1.5e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP83932.1 - 9.5e-08 31.9 0.1 1e-07 31.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AidB_N PF18158.1 GAP83935.1 - 5.9e-11 42.5 0.0 1.4e-10 41.3 0.0 1.5 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 GAP83935.1 - 1.1e-08 35.4 0.0 3.1e-08 34.0 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 GAP83935.1 - 0.011 16.0 0.0 0.03 14.6 0.0 1.8 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_S28 PF05577.12 GAP83936.1 - 1.8e-54 185.2 0.0 3e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 TPR_2 PF07719.17 GAP83938.1 - 1e-06 28.4 0.5 0.0043 17.1 0.1 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAP83938.1 - 1.5e-06 28.4 0.2 0.0065 16.7 0.1 3.7 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAP83938.1 - 0.00036 20.2 1.0 0.02 14.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAP83938.1 - 0.00064 20.2 0.2 0.0024 18.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAP83938.1 - 0.0028 18.3 0.1 9.3 7.4 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP83938.1 - 0.019 15.6 0.5 9.6 7.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAP83938.1 - 0.055 13.7 0.2 37 4.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAP83938.1 - 0.073 13.0 2.8 3.3 7.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAP83938.1 - 0.14 11.9 0.1 1.4 8.6 0.0 2.7 3 0 0 3 3 3 0 TPR repeat Sugar_tr PF00083.24 GAP83939.1 - 1.8e-110 369.9 18.6 2.1e-110 369.7 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP83939.1 - 7.1e-20 71.2 41.2 4.2e-15 55.5 10.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 GAP83939.1 - 0.0016 17.0 2.5 0.0025 16.3 0.3 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.20 GAP83939.1 - 0.022 13.1 4.2 0.056 11.7 3.1 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family UBA PF00627.31 GAP83940.1 - 0.00017 21.5 0.7 0.00035 20.4 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain TPR_1 PF00515.28 GAP83940.1 - 0.003 17.3 0.0 0.9 9.5 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAP83940.1 - 0.0054 16.8 0.0 0.4 10.9 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DnaJ PF00226.31 GAP83940.1 - 0.032 14.4 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 DnaJ domain TPR_12 PF13424.6 GAP83940.1 - 0.048 14.0 1.0 1 9.7 0.0 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1996 PF09362.10 GAP83941.1 - 2.2e-80 270.0 1.2 3.5e-80 269.4 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SOG2 PF10428.9 GAP83941.1 - 0.12 11.5 9.1 0.16 11.1 9.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4682 PF15733.5 GAP83942.1 - 5.8 7.5 6.9 0.77 10.4 1.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4682) Voldacs PF03517.13 GAP83943.1 - 3.9e-21 75.6 0.1 8.6e-21 74.5 0.1 1.6 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Zn_clus PF00172.18 GAP83946.1 - 7.5e-08 32.4 8.9 1.3e-07 31.6 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAP83946.1 - 0.00015 20.7 0.1 0.0002 20.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.15 GAP83947.1 - 1.2e-20 73.8 38.8 2.8e-20 72.5 38.8 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pro-kuma_activ PF09286.11 GAP83948.1 - 2.9e-38 131.3 0.3 1.5e-36 125.8 0.0 2.8 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAP83948.1 - 8.5e-09 35.1 0.1 1.5e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_18 PF00704.28 GAP83950.1 - 4.7e-11 43.0 0.0 6.5e-11 42.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 EXS PF03124.14 GAP83951.1 - 2.5e-99 332.8 31.5 3e-99 332.5 31.5 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 GAP83951.1 - 3.5e-84 284.0 2.0 7.2e-84 282.9 2.0 1.5 1 0 0 1 1 1 1 SPX domain FUR PF01475.19 GAP83951.1 - 0.17 12.0 0.1 0.4 10.8 0.1 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family p450 PF00067.22 GAP83952.1 - 3.1e-77 260.3 0.0 4.2e-77 259.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sld5 PF05916.11 GAP83952.1 - 0.26 11.8 1.6 0.59 10.6 1.6 1.5 1 0 0 1 1 1 0 GINS complex protein Peptidase_M18 PF02127.15 GAP83953.1 - 8.5e-130 433.4 0.0 1e-129 433.1 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) PAF-AH_p_II PF03403.13 GAP83954.1 - 2.5e-44 151.3 0.0 1.2e-40 139.2 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 GAP83954.1 - 0.00071 18.6 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 GAP83954.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.8 GAP83954.1 - 0.025 13.8 0.1 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 GAP83954.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Sporozoite_P67 PF05642.11 GAP83954.1 - 0.34 8.9 4.1 0.51 8.4 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPPII_N PF12583.8 GAP83954.1 - 0.55 10.8 4.7 0.89 10.1 4.7 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Mucin PF01456.17 GAP83954.1 - 0.64 10.0 16.4 1.3 9.1 16.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 GAP83954.1 - 1.9 6.3 5.4 2.6 5.9 5.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GCD14 PF08704.10 GAP83955.1 - 5.1e-59 199.9 0.0 7.2e-41 140.5 0.0 2.7 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit tRNA-synt_1e PF01406.19 GAP83956.1 - 7.5e-113 376.9 0.0 1.2e-112 376.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 GAP83956.1 - 1.4e-05 24.0 0.5 0.066 11.9 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 GAP83956.1 - 0.019 15.4 0.4 0.048 14.2 0.0 2.0 2 0 0 2 2 2 0 DALR domain HTH_34 PF13601.6 GAP83956.1 - 0.054 13.7 0.6 0.39 10.9 0.0 2.6 3 0 0 3 3 3 0 Winged helix DNA-binding domain LSM PF01423.22 GAP83957.1 - 2.1e-16 59.4 0.2 2.7e-16 59.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain tRNA-synt_1b PF00579.25 GAP83958.1 - 4.1e-17 62.4 0.0 4.2e-16 59.1 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF1656 PF07869.12 GAP83959.1 - 0.89 9.6 6.7 2.8 8.0 6.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DUF3176 PF11374.8 GAP83960.1 - 1.7e-28 98.9 1.4 3.2e-28 98.1 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) BRCT PF00533.26 GAP83961.1 - 0.016 15.5 0.0 0.082 13.3 0.0 2.2 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Chorion_3 PF05387.11 GAP83963.1 - 6.6 6.3 11.1 9 5.8 11.1 1.1 1 0 0 1 1 1 0 Chorion family 3 Zw10 PF06248.13 GAP83964.1 - 4.8e-11 41.9 5.8 3e-10 39.3 3.2 2.6 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 GAP83964.1 - 9.8e-05 22.1 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal DUF459 PF04311.13 GAP83964.1 - 0.011 14.7 0.4 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF459) Filament PF00038.21 GAP83964.1 - 0.1 12.1 0.1 0.1 12.1 0.1 2.1 2 1 1 3 3 3 0 Intermediate filament protein Peptidase_M16_C PF05193.21 GAP83965.1 - 3.8e-19 69.4 0.0 3.9e-15 56.4 0.0 3.8 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAP83965.1 - 6.1e-07 29.5 0.2 3.1e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) LPD22 PF18834.1 GAP83965.1 - 0.073 13.3 0.8 0.71 10.1 0.2 2.7 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 M16C_assoc PF08367.11 GAP83965.1 - 0.78 8.8 2.9 5.1 6.1 2.9 2.2 1 1 0 1 1 1 0 Peptidase M16C associated Polyketide_cyc2 PF10604.9 GAP83966.1 - 0.0011 19.2 1.6 0.017 15.4 1.1 2.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Molydop_binding PF01568.21 GAP83966.1 - 0.16 12.0 0.6 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain DIOX_N PF14226.6 GAP83968.1 - 2.4e-21 76.7 0.0 4.9e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP83968.1 - 1.3e-13 51.3 0.0 2.2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TetR_C_31 PF17940.1 GAP83968.1 - 0.08 13.2 0.3 5.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Glyco_hydro_61 PF03443.14 GAP83969.1 - 1.7e-51 175.1 0.1 2.1e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PilM PF07419.12 GAP83969.1 - 0.07 13.3 0.0 4.9 7.3 0.0 2.2 2 0 0 2 2 2 0 PilM zf-C2H2_4 PF13894.6 GAP83970.1 - 0.0053 17.5 15.2 0.39 11.7 0.1 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.12 GAP83970.1 - 0.0077 16.5 9.3 1.3 9.4 0.1 4.0 3 1 1 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 GAP83970.1 - 0.19 11.5 1.7 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 GAP83970.1 - 0.56 10.8 9.1 0.67 10.5 0.1 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type PMG PF05287.12 GAP83972.1 - 0.0033 17.5 4.0 0.0051 16.9 4.0 1.2 1 0 0 1 1 1 1 PMG protein Peptidase_M35 PF02102.15 GAP83973.1 - 1e-63 215.4 16.5 1.1e-63 215.2 16.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 GAP83973.1 - 1.1e-37 129.8 2.8 1.1e-37 129.8 2.8 1.5 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Grg1 PF11034.8 GAP83977.1 - 1.5e-30 105.2 14.5 1.7e-30 105.0 14.5 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 EBP PF05241.12 GAP83978.1 - 4.2e-66 221.8 9.6 4.9e-66 221.6 9.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein Gln-synt_C PF00120.24 GAP83979.1 - 5.9e-78 262.3 0.0 7.6e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain TFIIA PF03153.13 GAP83981.1 - 0.01 15.9 33.7 0.013 15.5 33.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 GAP83981.1 - 0.02 13.9 17.4 0.029 13.4 17.4 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 GAP83981.1 - 0.041 12.7 17.5 0.051 12.3 17.5 1.1 1 0 0 1 1 1 0 Presenilin Endostatin PF06482.11 GAP83981.1 - 0.059 12.8 11.9 0.071 12.6 11.9 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PAT1 PF09770.9 GAP83981.1 - 0.26 9.5 31.4 0.34 9.1 31.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Otopetrin PF03189.13 GAP83981.1 - 0.27 10.0 5.2 0.33 9.7 5.2 1.1 1 0 0 1 1 1 0 Otopetrin DDRGK PF09756.9 GAP83981.1 - 0.37 10.4 23.2 0.52 9.9 23.2 1.1 1 0 0 1 1 1 0 DDRGK domain Ndc1_Nup PF09531.10 GAP83981.1 - 0.44 9.2 5.7 0.46 9.1 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.12 GAP83981.1 - 0.67 9.7 14.0 0.92 9.3 14.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TERB2 PF15101.6 GAP83981.1 - 0.8 9.7 17.9 1.3 9.1 17.9 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 GREB1 PF15782.5 GAP83981.1 - 0.9 6.6 13.4 1.1 6.3 13.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Velvet PF11754.8 GAP83981.1 - 1.1 9.1 16.5 1.5 8.7 16.5 1.3 1 0 0 1 1 1 0 Velvet factor Exonuc_VII_L PF02601.15 GAP83981.1 - 1.3 8.6 14.5 1.5 8.3 14.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MDFI PF15316.6 GAP83981.1 - 1.5 8.9 6.4 2.1 8.4 6.4 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Sec62 PF03839.16 GAP83981.1 - 1.7 8.1 14.8 2.4 7.6 14.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 GAP83981.1 - 2 7.1 16.4 2.6 6.8 16.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 GAP83981.1 - 2.6 8.1 15.5 3.9 7.4 15.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 GAP83981.1 - 3.5 7.6 13.5 5.1 7.1 13.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A ALMT PF11744.8 GAP83981.1 - 3.7 6.3 13.3 5.1 5.8 13.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 GAP83981.1 - 4.6 6.2 17.5 6.2 5.7 17.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 ADSL_C PF10397.9 GAP83982.1 - 1.6e-14 54.2 0.0 5.6e-14 52.4 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Lyase_1 PF00206.20 GAP83982.1 - 1.7e-10 40.8 0.0 3.8e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Lyase RAI16-like PF10257.9 GAP83983.1 - 1e-70 238.4 2.8 1.6e-70 237.8 2.8 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein ORC6 PF05460.13 GAP83983.1 - 0.52 9.5 2.7 1.6 8.0 2.7 1.8 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DLH PF01738.18 GAP83984.1 - 8.5e-11 41.8 0.0 2.1e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Methyltransf_23 PF13489.6 GAP83985.1 - 2.3e-21 76.3 0.1 1.3e-20 73.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP83985.1 - 1.6e-10 41.5 0.0 4e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP83985.1 - 9.9e-08 31.9 0.0 4.9e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP83985.1 - 2e-06 28.4 0.0 1e-05 26.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP83985.1 - 9.7e-06 26.2 0.0 2.8e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAP83985.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Ubie_methyltran PF01209.18 GAP83985.1 - 0.032 13.6 0.0 0.38 10.1 0.0 2.4 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAP83985.1 - 0.037 13.6 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 GAP83985.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 GAP83985.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 GAP83985.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Spt20 PF12090.8 GAP83985.1 - 0.28 10.8 7.5 0.37 10.4 7.5 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 GAP83985.1 - 0.37 9.6 5.5 0.48 9.2 5.5 1.1 1 0 0 1 1 1 0 Androgen receptor T5orf172 PF10544.9 GAP83986.1 - 5.6e-25 87.9 0.0 1.4e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 GAP83986.1 - 3.3e-24 85.4 0.5 5.9e-24 84.5 0.1 1.7 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 Pyr_redox_2 PF07992.14 GAP83987.1 - 2.1e-20 73.1 0.5 3.1e-17 62.7 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP83987.1 - 6.8e-20 71.5 0.1 5.8e-19 68.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAP83987.1 - 8.4e-16 57.5 0.0 2.5e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAP83987.1 - 4.1e-15 55.8 0.9 3.8e-12 46.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 GAP83987.1 - 5.5e-08 33.3 0.4 0.015 15.8 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP83987.1 - 8.4e-07 29.1 0.2 5.2e-06 26.6 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 GAP83987.1 - 9.4e-06 25.7 0.1 0.0035 17.4 0.0 2.6 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 GAP83987.1 - 1.9e-05 24.1 0.1 0.085 12.2 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 GAP83987.1 - 2e-05 24.4 5.4 0.27 10.8 0.0 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP83987.1 - 2.1e-05 23.8 1.0 0.0034 16.5 0.3 2.4 2 0 0 2 2 2 1 FAD binding domain ThiF PF00899.21 GAP83987.1 - 3.3e-05 23.4 0.3 0.033 13.5 0.0 2.3 2 0 0 2 2 2 2 ThiF family FAD_binding_3 PF01494.19 GAP83987.1 - 3.6e-05 23.2 0.5 3.6e-05 23.2 0.5 1.9 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 GAP83987.1 - 0.0002 21.4 1.8 1.3 9.0 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAP83987.1 - 0.00036 20.0 0.8 0.0011 18.4 0.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAP83987.1 - 0.00039 19.8 0.1 0.46 9.7 0.0 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 GAP83987.1 - 0.00087 18.1 2.7 0.21 10.2 0.8 2.9 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.12 GAP83987.1 - 0.00096 18.3 1.5 0.023 13.7 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein TrkA_N PF02254.18 GAP83987.1 - 0.0015 18.8 0.5 2.2 8.6 0.1 2.5 2 0 0 2 2 2 2 TrkA-N domain Thi4 PF01946.17 GAP83987.1 - 0.0047 16.2 0.9 1.5 8.0 0.1 3.6 4 0 0 4 4 4 1 Thi4 family ApbA PF02558.16 GAP83987.1 - 0.0072 16.0 0.3 6.1 6.5 0.0 3.1 2 1 1 3 3 3 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 GAP83987.1 - 0.0083 15.7 0.1 0.73 9.4 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 GAP83987.1 - 0.019 14.1 3.8 2.3 7.2 0.1 3.8 4 0 0 4 4 4 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 GAP83987.1 - 0.068 13.1 0.5 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAP83987.1 - 0.081 12.2 0.3 5.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 GAP83987.1 - 0.086 13.3 0.1 3.7 8.0 0.1 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding MFS_1 PF07690.16 GAP83988.1 - 3.9e-35 121.4 61.5 3.9e-35 121.4 61.5 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP83988.1 - 2.3e-11 42.9 15.1 4.7e-11 41.8 15.1 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PRIMA1 PF16101.5 GAP83989.1 - 0.46 10.5 4.8 0.81 9.7 4.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Zn_clus PF00172.18 GAP83990.1 - 1.5 9.1 14.7 4.1 7.6 14.7 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FemAB PF02388.16 GAP83991.1 - 0.0057 15.6 0.7 0.0057 15.6 0.7 2.4 2 0 0 2 2 2 1 FemAB family Seryl_tRNA_N PF02403.22 GAP83991.1 - 0.21 11.8 19.4 1.5 9.1 6.7 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Flagellar_rod PF05149.12 GAP83991.1 - 0.27 10.7 17.1 1.7 8.1 1.6 2.4 1 1 1 2 2 2 0 Paraflagellar rod protein Macoilin PF09726.9 GAP83991.1 - 0.64 8.5 20.8 0.0071 15.0 9.5 2.3 2 0 0 2 2 2 0 Macoilin family DUF1664 PF07889.12 GAP83991.1 - 1.2 9.2 8.3 5.5 7.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ndc1_Nup PF09531.10 GAP83991.1 - 2.7 6.6 13.5 0.61 8.7 0.1 2.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF3287 PF11690.8 GAP83991.1 - 2.9 7.6 6.7 7 6.4 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) 4HBT_2 PF13279.6 GAP83992.1 - 1.6e-18 67.4 0.1 2.3e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 GAP83992.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Complex1_LYR_2 PF13233.6 GAP83993.1 - 0.002 18.9 1.0 0.0026 18.5 1.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAP83993.1 - 0.0036 17.3 0.1 0.0054 16.8 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_25 PF13649.6 GAP83994.1 - 1.5e-14 54.5 0.0 2.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP83994.1 - 1.2e-11 45.1 0.0 3.1e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP83994.1 - 2.4e-09 37.2 0.0 4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP83994.1 - 8.9e-07 28.5 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAP83994.1 - 8e-06 25.8 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP83994.1 - 2.7e-05 24.8 0.0 8.7e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAP83994.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 GAP83994.1 - 0.079 13.0 0.2 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Exo_endo_phos PF03372.23 GAP83995.1 - 2e-18 66.7 0.2 2.3e-17 63.3 0.2 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 GAP83995.1 - 1.1e-10 41.6 3.7 9.9e-06 25.8 0.2 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAP83995.1 - 5.6e-08 32.4 6.5 3.7e-07 29.8 0.5 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 GAP83995.1 - 1.6 9.6 7.1 6.4 7.7 0.2 4.0 4 1 0 4 4 4 0 Leucine Rich Repeat TFIIA PF03153.13 GAP83995.1 - 3.1 7.7 11.4 5.3 6.9 11.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_6 PF13516.6 GAP83995.1 - 3.6 7.9 6.6 5.6 7.3 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeat 2OG-FeII_Oxy PF03171.20 GAP83996.1 - 1.2e-13 51.4 0.0 2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 GAP83996.1 - 1.1e-09 39.1 0.0 1.8e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal tRNA-synt_1f PF01921.18 GAP83997.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) SKG6 PF08693.10 GAP83997.1 - 1.8 8.1 7.6 1.6 8.2 0.3 2.7 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Gemini_mov PF01708.16 GAP83999.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 Geminivirus putative movement protein Phage_Gp19 PF09355.10 GAP83999.1 - 0.16 12.4 0.1 0.34 11.4 0.1 1.5 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 Ribonuclease_T2 PF00445.18 GAP84000.1 - 9.7e-36 123.7 0.0 1.4e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family TPR_MLP1_2 PF07926.12 GAP84001.1 - 0.025 14.6 3.8 0.025 14.6 3.8 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 GAP84001.1 - 0.038 14.5 2.4 5.5 7.4 0.0 2.4 3 0 0 3 3 3 0 Fez1 RNA_lig_T4_1 PF09511.10 GAP84001.1 - 0.038 13.8 0.2 0.071 13.0 0.2 1.4 1 0 0 1 1 1 0 RNA ligase ATG16 PF08614.11 GAP84001.1 - 0.059 13.6 1.5 0.13 12.4 1.5 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CdvA PF18822.1 GAP84001.1 - 0.72 9.7 0.0 0.72 9.7 0.0 2.5 3 0 0 3 3 3 0 CdvA-like coiled-coil domain DUF676 PF05057.14 GAP84002.1 - 3.3e-06 26.8 0.1 5.8e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAP84002.1 - 7.9e-06 25.8 0.4 0.00013 21.8 0.1 2.3 1 1 1 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 GAP84002.1 - 3.3e-05 23.3 0.0 0.00017 20.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAP84002.1 - 5.3e-05 23.9 0.1 0.00011 22.8 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Macoilin PF09726.9 GAP84002.1 - 0.002 16.8 3.6 0.0026 16.4 3.6 1.2 1 0 0 1 1 1 1 Macoilin family Abhydrolase_1 PF00561.20 GAP84002.1 - 0.0065 16.1 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 GAP84002.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.12 GAP84002.1 - 0.035 14.1 0.0 0.09 12.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF900 PF05990.12 GAP84002.1 - 0.051 13.1 0.0 0.17 11.3 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.8 GAP84002.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 GAP84002.1 - 0.085 13.0 4.7 0.49 10.5 0.0 3.0 2 1 0 2 2 2 0 Thioesterase domain LCAT PF02450.15 GAP84002.1 - 0.09 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase AF-4 PF05110.13 GAP84002.1 - 0.11 10.5 18.8 0.16 10.0 18.8 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LIDHydrolase PF10230.9 GAP84002.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Cdh1_DBD_1 PF18196.1 GAP84002.1 - 0.46 10.8 11.5 1.1 9.6 11.5 1.6 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Atg14 PF10186.9 GAP84002.1 - 1 8.4 8.5 6.4 5.8 9.5 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DDHD PF02862.17 GAP84002.1 - 5.4 7.1 7.2 12 6.0 7.2 1.5 1 0 0 1 1 1 0 DDHD domain F-box-like PF12937.7 GAP84003.1 - 0.00025 20.9 0.1 0.00069 19.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 GAP84003.1 - 0.4 11.2 5.2 1 9.8 0.1 3.2 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Rox3 PF08633.10 GAP84004.1 - 5.9e-66 222.7 0.4 3.1e-65 220.3 0.1 1.9 2 0 0 2 2 2 1 Rox3 mediator complex subunit UQ_con PF00179.26 GAP84005.1 - 1.2e-35 122.1 0.0 1.6e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_4 PF14555.6 GAP84006.1 - 4.1e-05 23.3 0.1 9.2e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 GAP84006.1 - 0.29 11.1 3.7 0.88 9.6 3.7 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif DnaJ_C PF01556.18 GAP84007.1 - 8.2e-37 126.6 1.1 1.1e-36 126.2 1.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAP84007.1 - 4.3e-28 97.2 2.8 7.7e-28 96.4 2.8 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3274 PF11678.8 GAP84007.1 - 0.2 10.9 0.4 8.6 5.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3274) NAD_binding_4 PF07993.12 GAP84008.1 - 0.00013 21.3 0.0 0.00031 20.0 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 GAP84008.1 - 0.0012 18.3 0.0 0.006 16.1 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PBP PF01161.20 GAP84009.1 - 4.4e-11 43.2 0.0 5e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_60s PF00428.19 GAP84009.1 - 0.04 14.5 5.2 0.04 14.5 5.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Aminotran_1_2 PF00155.21 GAP84010.1 - 9.5e-43 146.7 0.0 1.2e-42 146.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II TauD PF02668.16 GAP84013.1 - 2.7e-24 86.4 0.0 4.4e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 GAP84013.1 - 0.073 12.2 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 CsiD Methyltransf_2 PF00891.18 GAP84014.1 - 3.9e-18 65.5 0.0 4.4e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 GAP84014.1 - 0.02 14.7 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 GAP84015.1 - 1.9e-79 262.3 0.0 3.9e-14 53.0 0.0 8.7 4 1 5 9 9 9 6 Ankyrin repeats (3 copies) Ank PF00023.30 GAP84015.1 - 2.1e-57 189.2 0.6 1.3e-05 25.4 0.0 14.2 15 0 0 15 15 15 11 Ankyrin repeat Ank_3 PF13606.6 GAP84015.1 - 6e-56 179.8 3.2 0.0025 18.2 0.0 15.1 15 0 0 15 15 14 11 Ankyrin repeat Ank_4 PF13637.6 GAP84015.1 - 2e-54 181.3 3.6 8.3e-10 39.0 0.0 8.7 7 3 2 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP84015.1 - 3e-36 123.0 3.5 1.1e-05 25.6 0.1 10.5 4 3 7 11 11 11 9 Ankyrin repeats (many copies) NACHT PF05729.12 GAP84015.1 - 3.3e-05 23.8 0.5 0.00011 22.2 0.1 2.1 2 0 0 2 2 2 1 NACHT domain DUF3734 PF12536.8 GAP84015.1 - 4e-05 23.9 0.7 1.4 9.3 0.0 6.0 7 0 0 7 7 7 1 Patatin phospholipase AAA_22 PF13401.6 GAP84015.1 - 0.00011 22.5 1.1 0.00025 21.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAP84015.1 - 0.0038 17.6 1.2 0.013 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ATLF PF07737.11 GAP84015.1 - 0.18 11.1 0.1 0.32 10.2 0.1 1.3 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain VWA_3_C PF18571.1 GAP84015.1 - 0.31 10.9 8.2 26 4.8 0.0 5.8 8 0 0 8 8 8 0 von Willebrand factor type A C-terminal domain DUF676 PF05057.14 GAP84017.1 - 0.0026 17.3 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 GAP84017.1 - 0.022 15.4 0.1 0.052 14.1 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family LCAT PF02450.15 GAP84017.1 - 0.042 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 GAP84017.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CBS PF00571.28 GAP84019.1 - 3.2e-21 75.5 5.5 2.7e-07 30.9 0.0 4.4 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.27 GAP84020.1 - 9.6e-13 48.2 0.0 1.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Spt20 PF12090.8 GAP84020.1 - 1.5 8.4 14.4 3.7 7.1 14.4 1.6 1 0 0 1 1 1 0 Spt20 family GHMP_kinases_N PF00288.26 GAP84020.1 - 7.1 7.0 8.0 6.4 7.1 3.7 2.7 1 1 1 2 2 2 0 GHMP kinases N terminal domain Zn_clus PF00172.18 GAP84021.1 - 1.3e-06 28.4 11.3 1.3e-06 28.4 11.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.7 GAP84021.1 - 2.4e-05 24.6 0.1 7.8e-05 22.9 0.1 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAP84021.1 - 0.0018 18.5 0.2 0.0018 18.5 0.2 2.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 GAP84021.1 - 0.0056 16.2 0.2 0.015 14.9 0.1 1.8 2 0 0 2 2 2 1 MYST family zinc finger domain zf-C2H2 PF00096.26 GAP84021.1 - 0.043 14.3 0.2 0.043 14.3 0.2 3.7 2 2 1 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP84021.1 - 0.2 12.6 0.7 0.2 12.6 0.7 4.0 3 1 1 4 4 4 0 C2H2-type zinc finger Metallophos PF00149.28 GAP84023.1 - 3.6e-19 70.1 0.6 6e-19 69.3 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nitroreductase PF00881.24 GAP84024.1 - 1.8e-13 50.9 0.0 2.4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family FAD_binding_1 PF00667.20 GAP84025.1 - 3e-42 144.7 0.0 4.3e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GAP84025.1 - 1e-08 35.8 0.0 3.2e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_3 PF01494.19 GAP84026.1 - 2.3e-12 46.9 6.8 1.9e-11 43.8 6.8 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAP84026.1 - 0.00018 21.7 0.6 0.00055 20.1 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP84026.1 - 0.0031 16.8 0.3 0.024 13.9 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP84026.1 - 0.0099 15.9 0.3 0.042 13.9 0.4 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.10 GAP84026.1 - 0.025 13.6 0.0 0.073 12.1 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Lycopene_cycl PF05834.12 GAP84026.1 - 0.047 12.7 0.3 0.047 12.7 0.3 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 GAP84026.1 - 0.069 12.4 0.5 0.13 11.5 0.5 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 GAP84026.1 - 0.31 10.1 5.9 0.029 13.5 1.3 1.6 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 GAP84026.1 - 0.32 10.5 11.0 0.045 13.3 2.6 2.9 1 1 1 3 3 3 0 FAD dependent oxidoreductase p450 PF00067.22 GAP84027.1 - 2.6e-36 125.3 0.1 2.6e-26 92.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Phage_spike PF18715.1 GAP84027.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Phage spike trimer CAP_N PF01213.19 GAP84027.1 - 2.6 7.4 6.9 5.6 6.3 6.9 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_25 PF13649.6 GAP84028.1 - 0.039 14.6 0.0 0.083 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAP84028.1 - 0.11 13.2 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PBP PF01161.20 GAP84029.1 - 2.1e-14 54.0 0.0 2.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein 2-Hacid_dh_C PF02826.19 GAP84030.1 - 1.3e-51 174.5 0.0 2.1e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP84030.1 - 5.2e-16 58.5 0.0 7.5e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 GAP84030.1 - 0.012 14.9 0.1 0.62 9.3 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TIMELESS PF04821.14 GAP84031.1 - 9.4e-84 280.9 0.3 2.7e-83 279.4 0.0 2.0 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 GAP84031.1 - 2.5e-31 109.5 14.3 2.5e-31 109.5 14.3 4.1 2 1 1 3 3 3 1 Timeless protein C terminal region KCT2 PF17818.1 GAP84031.1 - 2 8.5 5.4 1.2 9.2 2.1 2.4 1 1 1 2 2 2 0 Keratinocyte-associated gene product 3HCDH_N PF02737.18 GAP84032.1 - 6.9e-53 179.2 1.7 9e-53 178.8 1.7 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 GAP84032.1 - 3.2e-32 111.0 0.0 6.4e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 GAP84032.1 - 1.7e-05 25.0 0.4 4.8e-05 23.6 0.2 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 GAP84032.1 - 0.00071 19.8 0.5 0.002 18.3 0.4 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 GAP84032.1 - 0.0059 16.2 0.1 0.0082 15.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP84032.1 - 0.011 15.0 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAP84032.1 - 0.012 15.0 0.4 0.038 13.3 0.1 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAP84032.1 - 0.03 13.9 0.2 0.062 12.9 0.1 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PALP PF00291.25 GAP84032.1 - 0.065 12.6 1.0 0.085 12.2 0.1 1.6 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme F420_oxidored PF03807.17 GAP84032.1 - 1.4 9.6 4.5 1.4 9.5 1.8 2.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 GAP84033.1 - 3.2e-33 114.9 1.8 3.4e-33 114.8 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP84033.1 - 4.5e-08 33.1 8.6 9.4e-08 32.1 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 GAP84034.1 - 4.3e-69 232.8 0.0 6e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84034.1 - 7.9e-36 123.7 0.0 1.5e-35 122.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP84034.1 - 0.0016 17.8 0.1 0.0033 16.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAP84034.1 - 0.0054 16.1 0.2 0.031 13.6 0.1 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 GAP84034.1 - 0.014 15.0 0.1 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 GAP84034.1 - 0.031 13.2 0.1 0.17 10.8 0.1 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 GAP84034.1 - 0.2 10.4 0.0 0.2 10.4 0.0 2.4 2 0 0 2 2 2 0 Fungal protein kinase UL2 PF08196.11 GAP84035.1 - 0.19 11.7 1.5 0.54 10.2 1.5 1.8 1 0 0 1 1 1 0 UL2 protein DUF2011 PF09428.10 GAP84036.1 - 8.7e-21 74.0 0.2 4.7e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) NDT80_PhoG PF05224.12 GAP84038.1 - 8.3e-34 117.4 0.0 5.1e-33 114.8 0.0 2.1 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family IBR PF01485.21 GAP84040.1 - 2.2e-21 75.8 39.6 9.6e-15 54.6 4.0 4.2 3 1 1 4 4 4 4 IBR domain, a half RING-finger domain RWD PF05773.22 GAP84040.1 - 1.2e-15 57.8 0.0 2.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 GAP84040.1 - 5.7e-05 23.1 6.0 5.7e-05 23.1 6.0 3.7 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 GAP84040.1 - 0.00011 22.4 8.2 0.00011 22.4 8.2 3.9 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.25 GAP84040.1 - 0.00039 20.2 8.4 0.00039 20.2 8.4 4.2 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAP84040.1 - 0.019 15.1 4.5 0.019 15.1 4.5 4.3 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 GAP84040.1 - 0.11 12.3 9.2 0.38 10.5 9.2 2.0 1 0 0 1 1 1 0 RING-like zinc finger PAP2 PF01569.21 GAP84041.1 - 7.5e-13 48.4 1.4 7.5e-13 48.4 1.4 2.0 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 GAP84041.1 - 0.0014 18.8 0.0 0.046 13.9 0.0 2.2 2 0 0 2 2 2 1 Divergent PAP2 family DUF3810 PF12725.7 GAP84041.1 - 0.043 13.2 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3402 PF11882.8 GAP84042.1 - 1.7e-194 647.3 0.0 2.2e-194 646.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 GAP84042.1 - 8.4e-80 268.0 0.0 1.2e-79 267.5 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein GAS2 PF02187.17 GAP84043.1 - 1.2e-06 28.5 0.1 2.6e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain PQ-loop PF04193.14 GAP84044.1 - 1.7e-32 111.0 11.1 2.9e-17 62.2 3.3 3.1 3 0 0 3 3 3 2 PQ loop repeat SfLAP PF11139.8 GAP84044.1 - 0.059 12.8 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein GATase_4 PF13230.6 GAP84045.1 - 7e-17 61.2 0.0 2.6e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 GAP84045.1 - 1.7e-08 34.8 0.0 2.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Dynamin_N PF00350.23 GAP84046.1 - 1.7e-43 148.6 0.2 4.1e-43 147.3 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 GAP84046.1 - 2.2e-12 46.8 0.0 6.4e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 GAP84046.1 - 9.5e-07 28.9 0.1 0.083 13.0 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 GAP84046.1 - 0.027 14.8 0.4 0.26 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 GAP84046.1 - 0.028 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAP84046.1 - 0.071 12.8 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 GAP84049.1 - 4e-18 66.1 0.1 1.9e-17 63.9 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAP84049.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAP84049.1 - 0.01 16.3 0.4 0.043 14.2 0.3 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 GAP84049.1 - 0.034 14.6 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAP84049.1 - 0.083 13.2 0.2 0.48 10.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 GAP84049.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 GAP84049.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase PF06745.13 GAP84049.1 - 0.17 11.2 0.2 0.35 10.2 0.2 1.4 1 0 0 1 1 1 0 KaiC GSDH PF07995.11 GAP84050.1 - 0.00068 19.0 0.2 0.0034 16.7 0.0 2.0 2 1 1 3 3 3 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 GAP84050.1 - 0.0051 16.4 0.0 0.014 15.0 0.0 1.8 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region WD40 PF00400.32 GAP84050.1 - 0.05 14.5 1.2 77 4.4 0.2 4.5 3 1 1 4 4 4 0 WD domain, G-beta repeat RCC1_2 PF13540.6 GAP84050.1 - 0.11 12.4 1.4 37 4.3 0.1 3.7 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Orn_Arg_deC_N PF02784.16 GAP84053.1 - 3.5e-83 278.8 0.0 4.6e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 GAP84053.1 - 3.2e-18 65.8 0.0 4.3e-18 65.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 GAP84053.1 - 0.0022 17.5 0.0 0.0046 16.4 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HTH_Tnp_4 PF13613.6 GAP84054.1 - 0.056 13.2 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.6 GAP84054.1 - 0.069 13.0 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DUF2793 PF10983.8 GAP84054.1 - 0.14 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) HET PF06985.11 GAP84055.1 - 5.9e-24 85.1 0.0 1.4e-23 83.9 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ferric_reduct PF01794.19 GAP84056.1 - 7.6e-21 74.5 9.5 2.2e-20 73.0 9.5 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAP84056.1 - 0.047 13.8 0.2 0.097 12.8 0.2 1.4 1 0 0 1 1 1 0 FAD-binding domain M16C_assoc PF08367.11 GAP84057.1 - 1.2e-83 280.1 1.2 1.7e-83 279.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 GAP84057.1 - 3.5e-34 118.4 0.0 4.3e-23 82.3 0.0 3.2 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAP84057.1 - 3.4e-08 33.6 0.0 2.1e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) UvrA_inter PF17760.1 GAP84057.1 - 0.00067 19.7 0.9 0.0048 17.0 0.1 2.4 2 0 0 2 2 2 1 UvrA interaction domain Taxilin PF09728.9 GAP84058.1 - 1e-85 287.6 62.3 1.5e-85 287.1 62.3 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein PAH PF02671.21 GAP84058.1 - 0.14 12.4 2.3 0.8 9.9 0.5 2.7 2 0 0 2 2 2 0 Paired amphipathic helix repeat TMF_TATA_bd PF12325.8 GAP84058.1 - 1.2 9.4 54.8 1.5 9.0 15.9 4.8 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding LTV PF04180.14 GAP84059.1 - 2e-119 399.8 16.7 2.3e-119 399.6 16.7 1.0 1 0 0 1 1 1 1 Low temperature viability protein BAP PF06639.11 GAP84059.1 - 1.6 9.2 2.9 1 9.7 0.1 2.0 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) MMR_HSR1 PF01926.23 GAP84060.1 - 1.3e-17 63.9 0.3 1.7e-15 57.1 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAP84060.1 - 1.9e-07 30.7 0.4 4.5e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAP84060.1 - 6.3e-05 22.9 0.2 0.0053 16.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 GAP84060.1 - 0.0032 16.8 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 GAP84060.1 - 0.016 15.3 6.5 0.2 11.7 0.5 3.2 3 1 1 4 4 4 0 Dynamin family cobW PF02492.19 GAP84060.1 - 0.18 11.3 0.1 0.72 9.4 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RRP7 PF12923.7 GAP84061.1 - 0.099 12.8 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain TFIIF_alpha PF05793.12 GAP84061.1 - 0.41 9.2 3.4 0.46 9.0 3.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF11 PF01345.18 GAP84062.1 - 0.0012 19.1 0.3 0.0018 18.5 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF11 HCV_NS4a PF01006.20 GAP84062.1 - 0.1 12.4 0.4 0.26 11.1 0.1 1.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a DUF3506 PF12014.8 GAP84062.1 - 0.13 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Aldo_ket_red PF00248.21 GAP84063.1 - 5e-50 170.4 0.0 1.6e-49 168.7 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.6 GAP84064.1 - 5.2e-20 71.4 0.0 1.2e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP84064.1 - 2.7e-19 69.0 0.0 7.5e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAP84064.1 - 0.14 12.4 0.0 9.7 6.4 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAP84064.1 - 0.14 12.2 0.1 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 GAP84064.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Cerato-platanin PF07249.12 GAP84065.1 - 0.0096 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Cerato-platanin HET PF06985.11 GAP84066.1 - 4.7e-29 101.6 0.1 8.2e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M20 PF01546.28 GAP84067.1 - 1.9e-34 119.2 0.1 2.8e-34 118.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAP84067.1 - 6.8e-12 45.3 0.1 1.5e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAP84067.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M28 Abhydrolase_1 PF00561.20 GAP84069.1 - 1e-11 45.0 0.0 5e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP84069.1 - 0.014 14.7 0.0 0.05 12.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAP84069.1 - 0.014 16.1 0.1 0.018 15.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CutC PF03932.14 GAP84070.1 - 6.1e-26 91.2 0.2 8.2e-24 84.2 0.2 3.3 1 1 0 1 1 1 1 CutC family adh_short PF00106.25 GAP84071.1 - 1.4e-10 41.0 0.0 2.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84071.1 - 1.4e-09 37.9 0.1 1.6e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 GAP84071.1 - 0.078 12.3 0.1 0.18 11.1 0.1 1.6 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 GAP84071.1 - 0.092 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAP84071.1 - 0.12 12.5 0.2 0.25 11.4 0.1 1.7 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PGP_phosphatase PF09419.10 GAP84072.1 - 2.8e-63 212.5 0.0 3.3e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 GAP84072.1 - 1.1e-06 28.5 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like ORC2 PF04084.14 GAP84073.1 - 3e-121 404.4 0.0 3.8e-121 404.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 GFA PF04828.14 GAP84074.1 - 3.1e-10 40.2 0.7 8.6e-10 38.8 0.1 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Lipase_GDSL_2 PF13472.6 GAP84076.1 - 2.4e-14 54.1 0.1 3.8e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP84076.1 - 4.4e-08 33.3 0.0 7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 GAP84076.1 - 0.00036 20.7 0.1 0.0017 18.5 0.0 2.0 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 GAP84076.1 - 0.21 10.8 0.1 0.34 10.1 0.1 1.2 1 0 0 1 1 1 0 OSK domain Fasciclin PF02469.22 GAP84077.1 - 8.1e-22 77.8 0.2 3.3e-15 56.4 0.1 2.5 2 1 0 2 2 2 2 Fasciclin domain Pkinase PF00069.25 GAP84079.1 - 1.5e-70 237.6 0.0 2e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84079.1 - 7.7e-50 169.6 0.0 1.1e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP84079.1 - 1.1e-05 24.4 0.0 2.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAP84079.1 - 6.2e-05 22.5 0.0 0.00015 21.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Transglut_core PF01841.19 GAP84080.1 - 2.2e-09 37.8 1.0 4.6e-09 36.7 1.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 GAP84080.1 - 1.2e-08 34.5 0.2 2.7e-08 33.4 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAP84080.1 - 1.8e-07 30.7 1.2 3.5e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 GAP84080.1 - 0.0027 17.5 0.2 0.0055 16.5 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain Patatin PF01734.22 GAP84080.1 - 0.011 16.0 0.2 0.026 14.7 0.2 1.7 1 0 0 1 1 1 0 Patatin-like phospholipase Sugar_tr PF00083.24 GAP84081.1 - 5.9e-60 203.4 3.8 6.7e-60 203.2 3.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP84081.1 - 9.5e-14 51.1 11.5 1.2e-13 50.8 11.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Homeodomain PF00046.29 GAP84083.1 - 2.5e-17 62.5 4.8 5.7e-17 61.3 4.8 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAP84083.1 - 0.0027 17.6 0.1 0.0069 16.3 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain HCO3_cotransp PF00955.21 GAP84084.1 - 1.5e-79 268.2 6.7 9.6e-46 156.7 5.1 3.1 2 1 1 3 3 3 3 HCO3- transporter family Spt5_N PF11942.8 GAP84084.1 - 0.021 15.8 2.0 0.043 14.8 2.0 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Sulfate_transp PF00916.20 GAP84084.1 - 0.023 13.5 7.4 1.1 8.0 3.2 2.3 2 0 0 2 2 2 0 Sulfate permease family DUF4799 PF16056.5 GAP84084.1 - 0.16 11.1 0.3 0.31 10.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) Peptidase_M41 PF01434.18 GAP84085.1 - 1.8e-63 213.9 0.0 2.8e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAP84085.1 - 4.1e-42 143.7 0.0 9.5e-42 142.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 GAP84085.1 - 4.3e-12 46.3 0.1 1.6e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_lid_3 PF17862.1 GAP84085.1 - 9.3e-11 41.4 0.2 2.9e-10 39.8 0.1 1.9 1 1 1 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 GAP84085.1 - 0.0014 18.7 0.0 0.0049 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP84085.1 - 0.0014 18.9 0.3 0.14 12.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAP84085.1 - 0.0017 18.5 0.0 0.038 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAP84085.1 - 0.0018 18.1 0.0 0.019 14.7 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAP84085.1 - 0.014 15.8 0.2 0.9 9.9 0.1 2.8 1 1 0 2 2 2 0 AAA ATPase domain TIP49 PF06068.13 GAP84085.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 GAP84085.1 - 0.018 15.2 0.0 0.047 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAP84085.1 - 0.022 14.5 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 GAP84085.1 - 0.025 15.0 0.1 0.68 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Gram_pos_anchor PF00746.21 GAP84085.1 - 0.054 13.4 0.4 0.17 11.9 0.4 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif AAA_25 PF13481.6 GAP84085.1 - 0.078 12.6 0.4 1.4 8.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 GAP84085.1 - 0.18 11.1 0.2 0.38 10.1 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Fungal_trans PF04082.18 GAP84086.1 - 5.4e-23 81.4 0.0 1.1e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP84086.1 - 1.6e-08 34.5 8.3 2.8e-08 33.7 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.8 GAP84086.1 - 0.042 12.5 0.0 0.094 11.4 0.0 1.5 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Folliculin PF11704.8 GAP84086.1 - 0.53 10.2 2.3 0.45 10.4 0.1 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport GET2 PF08690.10 GAP84086.1 - 8.5 5.9 8.3 15 5.1 1.0 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 DUF4551 PF15087.6 GAP84087.1 - 2 7.1 10.3 3.8 6.2 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SURF6 PF04935.12 GAP84087.1 - 4.9 6.9 12.9 9.3 6.0 12.9 1.3 1 0 0 1 1 1 0 Surfeit locus protein 6 PAT1 PF09770.9 GAP84087.1 - 5.8 5.1 16.5 7.6 4.7 16.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF5301 PF17225.3 GAP84088.1 - 0.065 13.7 5.3 0.068 13.6 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) IGPD PF00475.18 GAP84089.1 - 3.1e-61 205.9 0.6 4.3e-61 205.4 0.6 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase MARVEL PF01284.23 GAP84090.1 - 0.0018 18.3 16.2 0.0032 17.5 16.2 1.4 1 1 0 1 1 1 1 Membrane-associating domain CENP-S PF15630.6 GAP84091.1 - 8.9e-35 118.9 0.0 1.4e-34 118.3 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 GAP84091.1 - 8.4e-09 35.5 0.0 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 GAP84091.1 - 0.01 15.8 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 GAP84091.1 - 0.022 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TAF PF02969.17 GAP84091.1 - 0.034 14.3 0.1 0.6 10.3 0.0 2.5 3 0 0 3 3 3 0 TATA box binding protein associated factor (TAF) PGA2 PF07543.12 GAP84092.1 - 2.5e-37 127.9 3.5 3.8e-37 127.3 3.5 1.3 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF3456 PF11938.8 GAP84092.1 - 0.02 15.4 1.5 0.03 14.8 1.5 1.2 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP AA_permease_2 PF13520.6 GAP84093.1 - 3.3e-44 151.4 30.6 4.1e-44 151.1 30.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP84093.1 - 3.2e-23 82.1 30.4 7.1e-23 80.9 30.4 1.4 1 1 0 1 1 1 1 Amino acid permease VPDSG-CTERM PF18205.1 GAP84093.1 - 0.91 9.4 5.0 2.7 7.9 0.4 3.5 2 0 0 2 2 2 0 VPDSG-CTERM motif Glyco_hydro_28 PF00295.17 GAP84095.1 - 2.1e-45 155.2 9.1 2.7e-45 154.9 9.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Malic_M PF03949.15 GAP84096.1 - 3.5e-91 305.0 0.0 4.6e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAP84096.1 - 4.7e-69 231.8 0.0 7.3e-69 231.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain NAD_binding_10 PF13460.6 GAP84098.1 - 2.8e-10 40.4 0.0 5.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP84098.1 - 4.9e-10 39.3 0.0 0.00044 19.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 GAP84098.1 - 6.5e-05 23.4 0.0 0.00016 22.1 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAP84098.1 - 0.00012 21.2 0.0 0.017 14.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 GAP84098.1 - 0.00038 20.7 0.0 0.00061 20.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 GAP84098.1 - 0.0014 18.2 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 GAP84098.1 - 0.0017 17.6 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 GAP84098.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 GAP84098.1 - 0.033 13.6 0.0 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAP84098.1 - 0.067 12.3 0.0 0.15 11.2 0.0 1.7 1 1 0 1 1 1 0 Male sterility protein DapB_N PF01113.20 GAP84098.1 - 0.08 13.1 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 GAP84098.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DJ-1_PfpI PF01965.24 GAP84099.1 - 1.7e-07 31.2 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family FAD_binding_4 PF01565.23 GAP84100.1 - 3e-21 75.6 1.4 4e-21 75.2 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain Mito_carr PF00153.27 GAP84101.1 - 3.8e-56 187.0 4.7 6e-19 67.8 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PG_binding_1 PF01471.18 GAP84101.1 - 0.027 14.7 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Serine_protease PF18405.1 GAP84101.1 - 4 6.5 9.7 10 5.2 0.1 3.6 3 2 0 3 3 3 0 Gammaproteobacterial serine protease DUF3042 PF11240.8 GAP84101.1 - 6.3 6.9 8.2 4.3 7.4 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3042) NIF PF03031.18 GAP84102.1 - 4.4e-21 75.3 0.0 5.8e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RRP36 PF06102.12 GAP84103.1 - 6.6e-51 172.6 18.5 6.6e-51 172.6 18.5 1.7 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 ABC1 PF03109.16 GAP84104.1 - 5.4e-30 104.0 0.0 9.9e-30 103.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family WD40 PF00400.32 GAP84105.1 - 4.1e-50 166.7 26.0 0.00012 22.8 0.0 11.6 11 1 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 GAP84105.1 - 7.9e-49 165.2 0.2 1.2e-48 164.6 0.2 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 GAP84105.1 - 8.1e-11 42.1 10.8 0.2 11.9 0.1 8.7 6 4 2 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP84105.1 - 4.5e-07 28.9 4.9 0.62 8.6 0.0 5.5 4 2 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAP84105.1 - 4.1e-06 25.8 5.0 6 5.5 0.0 6.1 5 2 2 7 7 7 4 Nup133 N terminal like Ge1_WD40 PF16529.5 GAP84105.1 - 0.00049 19.2 1.0 0.97 8.3 0.2 4.9 4 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein adh_short PF00106.25 GAP84108.1 - 1.3e-31 109.6 0.1 9e-23 80.7 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84108.1 - 1.1e-20 74.3 0.3 3.4e-18 66.1 0.3 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP84108.1 - 1.2e-07 31.9 0.1 2.2e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAP84108.1 - 1.9e-07 31.2 0.9 4.3e-07 30.0 0.9 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP84108.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAP84108.1 - 0.17 11.4 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Oxidored_FMN PF00724.20 GAP84109.1 - 1.1e-16 61.1 0.0 1.9e-15 57.0 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DUF561 PF04481.12 GAP84109.1 - 0.018 14.2 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Abhydrolase_1 PF00561.20 GAP84110.1 - 3.6e-25 89.1 0.1 7.2e-25 88.1 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP84110.1 - 2.6e-20 74.0 19.9 7.1e-20 72.5 19.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP84110.1 - 1.3e-10 41.0 0.1 3.3e-07 29.8 0.5 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 GAP84110.1 - 0.00014 20.6 0.0 0.00021 20.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 GAP84110.1 - 0.13 11.1 0.1 0.36 9.7 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme Mito_carr PF00153.27 GAP84111.1 - 5.4e-72 237.8 1.2 6.7e-26 90.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GAP84111.1 - 1.4e-18 67.1 3.8 4.8e-08 33.3 0.3 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 GAP84111.1 - 3.6e-18 63.7 4.0 4e-06 26.0 0.0 6.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 GAP84111.1 - 3.8e-18 63.8 1.1 1.8e-05 24.3 0.0 6.1 6 0 0 6 6 6 3 EF-hand domain EF-hand_5 PF13202.6 GAP84111.1 - 4.7e-11 41.7 1.4 0.00061 19.2 0.1 4.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 GAP84111.1 - 8.3e-10 38.4 0.8 0.0024 17.7 0.1 5.5 4 2 1 5 5 5 3 EF-hand domain pair Arena_nucleocap PF00843.17 GAP84111.1 - 0.0099 14.8 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 1 Arenavirus nucleocapsid N-terminal domain Dockerin_1 PF00404.18 GAP84111.1 - 0.014 15.5 0.0 0.077 13.2 0.0 2.2 2 0 0 2 2 2 0 Dockerin type I domain MurB_C PF02873.16 GAP84111.1 - 0.062 13.4 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain EF-hand_9 PF14658.6 GAP84111.1 - 0.075 13.4 0.0 64 4.0 0.0 3.9 3 1 0 3 3 3 0 EF-hand domain Cyclin_N PF00134.23 GAP84112.1 - 1.1e-44 151.3 0.0 1.9e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAP84112.1 - 5.8e-36 123.2 0.2 1.4e-35 122.0 0.1 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Zn_clus PF00172.18 GAP84114.1 - 0.00063 19.8 11.7 0.0012 18.9 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 GAP84114.1 - 0.008 15.6 0.1 0.038 13.4 0.1 2.2 1 0 0 1 1 1 1 Histone chaperone domain CHZ MFS_1 PF07690.16 GAP84115.1 - 6.8e-25 87.7 22.5 9.4e-25 87.3 22.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2427 PF10348.9 GAP84115.1 - 0.069 12.9 4.0 0.4 10.5 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) Abhydrolase_6 PF12697.7 GAP84116.1 - 2.5e-05 25.0 6.3 3e-05 24.7 6.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAP84116.1 - 0.00024 21.0 3.6 0.0043 16.9 0.3 3.2 3 1 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP84116.1 - 0.0054 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAP84116.1 - 0.0068 16.6 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 GAP84116.1 - 0.024 14.3 0.1 0.045 13.4 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.8 GAP84116.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF915 PF06028.11 GAP84116.1 - 0.23 10.8 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) RNA_pol_Rpc4 PF05132.14 GAP84117.1 - 3.6e-22 79.4 0.1 3.6e-22 79.4 0.1 4.0 3 3 1 4 4 4 1 RNA polymerase III RPC4 DUF3073 PF11273.8 GAP84117.1 - 0.15 12.8 0.1 0.15 12.8 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3073) UreD PF01774.17 GAP84118.1 - 7.4e-74 248.2 0.0 8.7e-74 248.0 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.11 GAP84119.1 - 1.1e-33 115.5 0.1 2.7e-32 111.0 0.0 3.1 2 0 0 2 2 2 1 STAG domain Cnd1 PF12717.7 GAP84119.1 - 1.2e-05 25.4 0.2 0.083 12.9 0.2 3.1 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAP84119.1 - 3.7e-05 24.0 0.0 0.0054 17.1 0.0 2.8 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 GAP84119.1 - 0.0023 18.0 0.4 19 5.8 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat POT1PC PF16686.5 GAP84120.1 - 2.8e-42 144.2 1.3 5.8e-42 143.2 0.1 2.2 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 GAP84120.1 - 1.6e-14 53.9 0.0 3.7e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 PIEZO PF15917.5 GAP84120.1 - 3.4 7.1 0.0 3.4 7.1 0.0 2.6 3 0 0 3 3 3 0 Piezo Arm PF00514.23 GAP84121.1 - 1.6e-95 310.6 15.9 1.9e-13 49.9 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 GAP84121.1 - 5.9e-28 97.2 1.9 1.1e-27 96.3 0.7 2.1 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 GAP84121.1 - 1.5e-23 82.1 5.1 4.4e-23 80.6 3.8 2.2 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 GAP84121.1 - 2.4e-21 75.8 11.7 5.4e-09 36.4 0.2 6.6 6 1 1 7 7 7 4 HEAT-like repeat HEAT_2 PF13646.6 GAP84121.1 - 1.6e-18 66.9 0.2 1.4e-08 35.0 0.0 5.4 1 1 4 5 5 5 3 HEAT repeats HEAT PF02985.22 GAP84121.1 - 1.2e-17 62.5 3.8 1.7e-05 24.7 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 GAP84121.1 - 1e-07 31.7 0.0 0.019 14.5 0.0 3.7 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 GAP84121.1 - 3.2e-05 22.7 0.0 0.0025 16.4 0.0 2.7 1 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 GAP84121.1 - 0.00019 21.5 0.0 1.8 8.7 0.0 4.3 3 2 1 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.16 GAP84121.1 - 0.00086 19.8 0.5 1.9 9.4 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 GAP84121.1 - 0.0027 17.8 0.0 5.4 7.0 0.0 3.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 GAP84121.1 - 0.031 14.5 5.6 3 8.1 0.1 4.8 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 GAP84121.1 - 0.046 13.3 0.0 6 6.4 0.0 3.5 2 1 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 6PF2K PF01591.18 GAP84122.1 - 4.6e-61 206.0 0.1 6.3e-61 205.5 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAP84122.1 - 1.6e-20 73.6 1.0 5.7e-19 68.6 1.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAP84122.1 - 0.0082 16.3 0.0 0.037 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Porin_3 PF01459.22 GAP84123.1 - 6.6e-79 265.2 0.6 7.7e-79 264.9 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin SPC22 PF04573.12 GAP84124.1 - 2.7e-12 46.5 1.2 6.9e-08 32.2 0.1 2.1 1 1 1 2 2 2 2 Signal peptidase subunit Peptidase_C48 PF02902.19 GAP84125.1 - 3.1e-33 115.4 0.0 9.1e-33 113.9 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MFS18 PF17352.2 GAP84126.1 - 0.044 14.2 0.9 0.044 14.2 0.9 2.7 2 1 1 3 3 3 0 Male Flower Specific protein 18 WSC PF01822.19 GAP84127.1 - 3.2e-70 232.3 55.6 5.3e-19 68.2 5.6 4.5 4 0 0 4 4 4 4 WSC domain peroxidase PF00141.23 GAP84127.1 - 1.5e-20 73.9 0.0 2.8e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Peroxidase SUI1 PF01253.22 GAP84128.1 - 1.6e-25 89.5 1.4 2.1e-25 89.0 1.4 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ribosomal_L4 PF00573.22 GAP84129.1 - 4.4e-37 127.6 0.1 5.7e-37 127.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 GAP84129.1 - 4e-26 90.9 1.6 4.9e-26 90.6 0.1 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Aminotran_1_2 PF00155.21 GAP84130.1 - 4.2e-07 29.5 0.0 8.1e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II MTHFR PF02219.17 GAP84133.1 - 8.5e-102 340.3 0.0 1.2e-101 339.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase HTH_WhiA PF02650.14 GAP84134.1 - 3.3e-07 30.6 0.1 0.00023 21.5 0.0 2.7 3 0 0 3 3 3 2 WhiA C-terminal HTH domain PQ-loop PF04193.14 GAP84135.1 - 2.1e-18 65.9 2.2 6.6e-12 45.0 0.4 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 GAP84135.1 - 0.74 10.6 6.6 8 7.3 6.6 2.1 1 1 0 1 1 1 0 ER lumen protein retaining receptor Zn_clus PF00172.18 GAP84136.1 - 6e-07 29.5 8.3 9.7e-07 28.8 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cohesin_load PF10345.9 GAP84138.1 - 1e-127 427.1 12.7 1e-127 427.1 12.7 1.6 2 0 0 2 2 2 1 Cohesin loading factor EPL1 PF10513.9 GAP84138.1 - 0.87 10.0 16.6 1.9 8.9 16.6 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like Presenilin PF01080.17 GAP84138.1 - 2.3 6.9 24.3 35 3.0 23.9 2.2 2 0 0 2 2 2 0 Presenilin Peptidase_S64 PF08192.11 GAP84138.1 - 5.8 5.3 15.0 9 4.6 15.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 SpoIIP PF07454.11 GAP84138.1 - 9.7 5.5 19.7 16 4.8 19.7 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Abhydrolase_1 PF00561.20 GAP84140.1 - 3.8e-16 59.5 0.0 6.5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP84140.1 - 4.9e-10 39.1 0.0 2.3e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Cutinase PF01083.22 GAP84140.1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Cutinase RAI1 PF08652.11 GAP84141.1 - 2.1e-28 98.3 0.1 5.4e-28 97.0 0.0 1.8 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease TPALS PF18178.1 GAP84142.1 - 0.049 13.1 0.6 0.071 12.5 0.6 1.2 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family DUF410 PF04190.13 GAP84143.1 - 4e-90 302.1 0.0 4.9e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) EHN PF06441.12 GAP84145.1 - 4.4e-22 78.5 0.0 8.6e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus ELO PF01151.18 GAP84146.1 - 3.8e-63 213.3 20.0 5.1e-63 212.9 20.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family adh_short PF00106.25 GAP84148.1 - 2e-16 60.0 0.0 6.6e-12 45.3 0.1 2.4 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84148.1 - 1.2e-09 38.1 0.0 3.6e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 GAP84148.1 - 0.014 15.1 0.3 0.028 14.2 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_oxidored PF12831.7 GAP84148.1 - 0.051 12.9 0.2 0.069 12.5 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase KR PF08659.10 GAP84148.1 - 0.28 11.1 0.9 0.96 9.3 0.9 1.8 1 1 0 1 1 1 0 KR domain COX5A PF02284.16 GAP84149.1 - 2.9e-41 139.6 0.3 3.6e-41 139.3 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va HDA2-3 PF11496.8 GAP84150.1 - 2.8e-06 26.7 2.7 0.00011 21.5 2.7 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERM PF00769.19 GAP84150.1 - 9.7 5.9 22.9 8.3 6.1 14.4 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Chromo PF00385.24 GAP84151.1 - 2.4e-05 24.2 0.1 3.7e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Trypan_PARP PF05887.11 GAP84151.1 - 0.00013 21.9 5.3 0.00013 21.9 5.3 2.1 2 1 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 GAP84151.1 - 0.73 8.2 8.5 1 7.8 8.5 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein GMC_oxred_C PF05199.13 GAP84152.1 - 3.7e-10 40.5 0.1 7.4e-08 33.0 0.1 2.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 GAP84152.1 - 2.2e-08 33.9 0.0 1.2e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAP84152.1 - 6.6e-05 22.2 0.1 0.00011 21.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAP84152.1 - 0.00014 22.0 0.3 0.00044 20.4 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAP84152.1 - 0.00038 19.9 0.1 0.00065 19.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP84152.1 - 0.00044 19.6 0.1 0.0087 15.3 0.1 2.3 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP84152.1 - 0.009 15.1 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 GAP84152.1 - 0.048 12.4 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 GAP84152.1 - 0.061 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAP84152.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAP84152.1 - 0.2 12.2 0.0 0.2 12.2 0.0 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.21 GAP84154.1 - 4.6e-82 275.4 4.2 5.7e-82 275.1 4.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 GAP84154.1 - 2.1e-50 170.0 0.0 4.2e-50 169.0 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 GAP84154.1 - 0.0049 17.3 0.1 0.011 16.2 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding DNA_pol_B PF00136.21 GAP84155.1 - 3.8e-149 497.3 1.8 4.9e-149 496.9 1.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAP84155.1 - 7.2e-78 262.1 0.0 3.3e-77 259.9 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GAP84155.1 - 1.2e-17 64.1 4.9 2.6e-17 63.0 4.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 GAP84155.1 - 0.00083 19.4 0.2 0.0091 16.0 0.2 2.5 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.13 GAP84155.1 - 0.0018 17.2 0.5 0.13 11.1 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 GAP84155.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Peptidase_M48_N PF16491.5 GAP84156.1 - 3.2e-65 219.4 7.5 3.2e-65 219.4 7.5 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 GAP84156.1 - 4.3e-47 160.4 0.1 7.7e-47 159.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 GAP84156.1 - 0.00012 21.4 0.1 0.0002 20.7 0.1 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 SprT-like PF10263.9 GAP84156.1 - 0.065 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 SprT-like family DUF4538 PF15061.6 GAP84156.1 - 0.38 10.5 5.4 0.19 11.5 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Ish1 PF10281.9 GAP84157.1 - 1.4e-06 28.5 0.2 2e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.27 GAP84157.1 - 0.038 13.7 0.0 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 SAP domain DNA_meth_N PF18284.1 GAP84157.1 - 0.28 11.1 1.7 0.42 10.6 1.7 1.4 1 1 0 1 1 1 0 DNA methylase N-terminal domain Ribosomal_L38e PF01781.18 GAP84158.1 - 1.1e-32 111.9 4.7 1.3e-32 111.6 4.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family ABM PF03992.16 GAP84159.1 - 2.7e-05 24.2 7.2 0.015 15.4 4.3 3.4 2 2 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 GAP84159.1 - 0.05 13.9 0.3 3.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) GHMP_kinases_N PF00288.26 GAP84160.1 - 2.2e-16 59.8 0.0 2.2e-16 59.8 0.0 2.3 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAP84160.1 - 1.5e-07 31.7 0.1 3.4e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 GAP84160.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature GvpG PF05120.12 GAP84160.1 - 0.038 14.0 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 Gas vesicle protein G PPTA PF01239.22 GAP84161.1 - 6.9e-35 117.8 16.4 9.4e-07 28.4 0.4 6.0 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.6 GAP84161.1 - 0.0031 18.0 0.1 0.97 10.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP84161.1 - 0.032 14.2 1.5 1.3 9.2 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAP84161.1 - 0.07 13.4 1.4 1.7 9.0 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF572 PF04502.13 GAP84162.1 - 4.6e-71 240.2 4.3 5.2e-71 240.0 4.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) IBR PF01485.21 GAP84162.1 - 0.079 13.2 1.8 0.14 12.4 1.8 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-ACC PF17848.1 GAP84162.1 - 5.3 7.2 6.5 14 5.9 0.4 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain GCP_N_terminal PF17681.1 GAP84163.1 - 4.4e-37 128.3 0.0 8.5e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAP84163.1 - 1.8e-26 93.4 0.8 1.8e-26 93.4 0.8 2.0 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 GAP84163.1 - 4.9e-08 31.8 0.0 7.8e-08 31.1 0.0 1.2 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.16 GAP84164.1 - 5.8e-113 377.4 5.1 6.9e-113 377.2 5.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.32 GAP84165.1 - 1.6e-20 73.0 3.0 0.00017 22.3 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP84165.1 - 1.2e-08 35.1 0.0 0.05 13.9 0.0 5.6 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 GAP84165.1 - 0.0023 17.4 0.1 0.53 9.7 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) Cytochrom_D1 PF02239.16 GAP84165.1 - 0.014 13.9 0.2 0.042 12.4 0.1 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ PF01011.21 GAP84165.1 - 0.16 11.9 4.4 28 4.9 0.0 4.1 5 0 0 5 5 5 0 PQQ enzyme repeat Pet127 PF08634.10 GAP84166.1 - 5.9e-120 399.8 4.4 8.7e-120 399.3 4.4 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Serglycin PF04360.12 GAP84167.1 - 0.022 14.7 2.0 0.022 14.7 2.0 2.2 2 0 0 2 2 2 0 Serglycin HGTP_anticodon2 PF12745.7 GAP84168.1 - 5.4e-76 255.6 0.0 5.4e-76 255.6 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 GAP84168.1 - 1.9e-75 253.6 0.0 5.1e-34 117.8 0.0 4.7 5 0 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84168.1 - 8.3e-43 146.5 0.0 4.3e-16 59.0 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 GAP84168.1 - 5.4e-16 58.7 0.0 1.2e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.22 GAP84168.1 - 2.9e-13 50.1 0.1 9.5e-13 48.5 0.1 1.9 1 0 0 1 1 1 1 RWD domain APH PF01636.23 GAP84168.1 - 0.00015 21.7 6.8 0.13 12.1 0.1 3.3 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAP84168.1 - 0.0078 15.0 2.9 1 8.1 2.5 2.8 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 GAP84168.1 - 0.012 15.0 0.0 0.18 11.1 0.0 2.4 3 0 0 3 3 3 0 Kinase-like HGTP_anticodon PF03129.20 GAP84168.1 - 0.015 15.4 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 Anticodon binding domain FTA2 PF13095.6 GAP84168.1 - 0.074 12.7 3.9 2.4 7.7 0.0 3.5 4 0 0 4 4 3 0 Kinetochore Sim4 complex subunit FTA2 Vps23_core PF09454.10 GAP84168.1 - 0.28 11.2 1.2 2.2 8.3 0.2 2.8 3 0 0 3 3 3 0 Vps23 core domain DUF1682 PF07946.14 GAP84168.1 - 1.9 7.7 11.5 2.8 7.1 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.12 GAP84168.1 - 2 8.2 8.3 4.4 7.0 8.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cut12 PF11500.8 GAP84169.1 - 8.3e-39 132.8 18.1 8.3e-39 132.8 18.1 4.8 3 1 0 4 4 4 1 Spindle pole body formation-associated protein UreF PF01730.16 GAP84169.1 - 8.7e-10 39.3 6.5 8.7e-10 39.3 6.5 2.6 2 0 0 2 2 2 1 UreF Golgin_A5 PF09787.9 GAP84169.1 - 0.0015 18.1 19.4 0.0015 18.1 19.4 3.1 2 1 0 3 3 3 1 Golgin subfamily A member 5 Pox_A_type_inc PF04508.12 GAP84169.1 - 0.12 12.3 24.3 0.31 10.9 0.1 6.0 5 1 1 6 6 6 0 Viral A-type inclusion protein repeat GAS PF13851.6 GAP84169.1 - 0.24 10.7 38.5 0.038 13.3 20.1 3.1 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding E1-E2_ATPase PF00122.20 GAP84169.1 - 0.73 9.3 4.3 3.7 7.0 0.4 2.5 2 0 0 2 2 2 0 E1-E2 ATPase Bacillus_HBL PF05791.11 GAP84169.1 - 9 6.1 13.7 4.6 7.0 3.2 3.0 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Torus PF16131.5 GAP84170.1 - 1.3e-42 144.9 0.3 3.8e-42 143.4 0.3 1.8 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 GAP84170.1 - 9.6e-08 31.7 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 GAP84170.1 - 0.00013 21.9 0.6 0.00013 21.9 0.6 1.9 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 GAP84170.1 - 0.0097 15.8 0.7 0.02 14.8 0.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 GAP84170.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Acyl-CoA_dh_1 PF00441.24 GAP84171.1 - 4.2e-30 104.9 0.4 7.8e-30 104.1 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAP84171.1 - 1e-19 70.5 0.0 1.8e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAP84171.1 - 4e-13 50.0 0.1 9.3e-13 48.8 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAP84171.1 - 4.1e-13 49.8 0.9 9.9e-13 48.5 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Spo12 PF05032.12 GAP84172.1 - 1.2e-15 57.1 0.3 2.2e-15 56.3 0.3 1.5 1 0 0 1 1 1 1 Spo12 family MMR_HSR1_Xtn PF16897.5 GAP84173.1 - 1.7e-34 118.0 1.2 7e-34 116.0 0.5 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 GAP84173.1 - 2.4e-20 72.7 0.0 5.9e-20 71.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 GAP84173.1 - 1.5e-19 69.7 0.1 2.8e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 GAP84173.1 - 1.7e-12 47.1 0.0 2.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAP84173.1 - 0.00014 21.9 0.2 0.11 12.6 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 GAP84173.1 - 0.079 11.9 0.1 0.17 10.9 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 GAP84173.1 - 0.1 11.7 0.1 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain TPR_12 PF13424.6 GAP84174.1 - 5.3e-33 113.2 15.6 5.2e-12 45.9 0.1 7.0 6 2 3 9 9 7 5 Tetratricopeptide repeat NB-ARC PF00931.22 GAP84174.1 - 6.1e-22 78.0 0.0 1.1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 GAP84174.1 - 1.5e-19 69.2 18.0 2.7e-06 27.1 0.1 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAP84174.1 - 1.3e-12 46.9 1.6 0.18 12.1 0.1 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP84174.1 - 3.9e-10 39.0 7.8 0.16 12.0 0.1 7.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAP84174.1 - 4.9e-10 38.8 3.4 0.028 14.3 0.0 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAP84174.1 - 8e-09 35.0 7.7 1.8 8.8 0.0 8.5 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAP84174.1 - 3.6e-08 33.6 12.5 1.9 9.5 0.0 8.5 6 2 2 8 8 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAP84174.1 - 2.6e-07 30.4 7.6 2.7e-06 27.0 1.6 3.8 3 1 0 3 3 3 1 MalT-like TPR region AAA_16 PF13191.6 GAP84174.1 - 1.1e-06 29.2 0.2 1.2e-05 25.7 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain Goodbye PF17109.5 GAP84174.1 - 1.8e-05 25.2 0.0 7.6e-05 23.2 0.0 2.2 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain TPR_19 PF14559.6 GAP84174.1 - 2.6e-05 24.6 4.3 0.062 13.8 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAP84174.1 - 0.00032 21.0 0.4 2.8 8.8 0.0 4.6 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAP84174.1 - 0.012 16.2 12.9 0.51 11.0 0.3 6.2 5 1 1 6 6 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 GAP84174.1 - 0.016 15.5 0.0 0.075 13.3 0.0 2.2 2 0 0 2 2 1 0 AAA domain TPR_17 PF13431.6 GAP84174.1 - 0.023 15.1 0.2 25 5.5 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 GAP84174.1 - 0.051 13.8 0.1 9.2 6.8 0.0 3.7 4 0 0 4 4 2 0 PPR repeat TPR_6 PF13174.6 GAP84174.1 - 0.078 13.7 8.1 74 4.3 0.0 6.8 8 0 0 8 8 5 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 GAP84174.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_11 PF13414.6 GAP84174.1 - 0.11 12.2 1.9 90 2.9 0.1 4.5 4 0 0 4 4 4 0 TPR repeat ATPase PF06745.13 GAP84174.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF4487 PF14868.6 GAP84175.1 - 0.074 11.9 0.0 0.092 11.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) Peptidase_M49 PF03571.15 GAP84176.1 - 4.4e-202 672.3 0.0 5.2e-202 672.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 GFO_IDH_MocA PF01408.22 GAP84177.1 - 8e-11 42.8 0.9 3.7e-10 40.7 0.9 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 GAP84177.1 - 0.14 12.8 0.0 0.22 12.2 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 GAP84177.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain DHDPS PF00701.22 GAP84178.1 - 1.1e-31 109.7 0.0 1.2e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DAO PF01266.24 GAP84179.1 - 1.8e-65 221.9 3.7 2.2e-65 221.6 3.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP84179.1 - 0.00015 21.1 0.1 0.0038 16.5 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP84179.1 - 0.00024 21.2 0.4 0.00072 19.7 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAP84179.1 - 0.0013 19.2 0.1 0.088 13.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAP84179.1 - 0.0027 16.6 1.0 0.004 16.1 0.4 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 GAP84179.1 - 0.0095 16.2 0.8 0.051 13.8 0.1 2.4 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain MCRA PF06100.11 GAP84179.1 - 0.06 12.1 0.0 0.16 10.7 0.1 1.6 2 0 0 2 2 2 0 MCRA family NAD_binding_9 PF13454.6 GAP84179.1 - 0.064 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Spermine_synth PF01564.17 GAP84179.1 - 0.08 12.3 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Thi4 PF01946.17 GAP84179.1 - 0.087 12.0 1.0 0.13 11.5 0.2 1.6 2 0 0 2 2 2 0 Thi4 family GSHPx PF00255.19 GAP84180.1 - 1.6e-37 127.4 0.0 2.1e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 GAP84180.1 - 0.00025 20.9 0.1 0.00081 19.3 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAP84180.1 - 0.0058 16.3 0.2 0.0074 16.0 0.2 1.3 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.6 GAP84180.1 - 0.15 12.6 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Inhibitor_Mig-6 PF11555.8 GAP84182.1 - 0.019 15.1 0.1 0.055 13.6 0.1 1.9 1 1 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Fungal_trans_2 PF11951.8 GAP84183.1 - 2.3e-53 181.4 0.3 4.2e-53 180.6 0.3 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Nop16 PF09420.10 GAP84184.1 - 2.9e-63 213.7 0.2 3.3e-63 213.5 0.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 MARVEL PF01284.23 GAP84185.1 - 2.8e-06 27.4 9.2 5.1e-06 26.6 9.2 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.6 GAP84185.1 - 0.0034 17.7 0.5 0.0057 17.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) SCAMP PF04144.13 GAP84185.1 - 0.016 15.5 3.4 0.023 15.0 3.4 1.1 1 0 0 1 1 1 0 SCAMP family MKT1_C PF12246.8 GAP84186.1 - 2.8e-70 236.3 0.0 4e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 GAP84186.1 - 2.3e-28 98.3 0.0 4.7e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 GAP84186.1 - 0.00085 19.8 0.0 0.015 15.8 0.0 2.4 2 0 0 2 2 2 1 XPG N-terminal domain DIOX_N PF14226.6 GAP84187.1 - 1.3e-21 77.6 0.0 2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP84187.1 - 2.1e-12 47.4 0.0 4.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 GAP84190.1 - 5.3e-09 36.1 11.1 1e-08 35.1 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAP84190.1 - 2e-05 23.6 0.1 9.6e-05 21.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 GAP84191.1 - 3.9e-14 52.3 0.8 7.2e-14 51.4 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP84191.1 - 2.8e-07 30.6 9.8 5.3e-07 29.7 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 GAP84192.1 - 2.3e-82 276.0 0.0 2.9e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP84192.1 - 1.1e-07 32.0 0.1 3.6e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding DUF3798 PF12683.7 GAP84192.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) DUF2498 PF10692.9 GAP84192.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) DNA_pol_E_B PF04042.16 GAP84194.1 - 2.5e-50 170.8 0.0 3.3e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 GAP84194.1 - 8.8e-37 126.1 0.0 1.3e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain WD40 PF00400.32 GAP84195.1 - 7.5e-20 70.9 12.9 2.7e-07 31.2 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.12 GAP84195.1 - 3.3e-16 59.6 0.2 5.3e-16 58.9 0.2 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 GAP84195.1 - 0.012 14.3 0.6 0.71 8.4 0.0 3.3 2 2 2 4 4 4 0 Nucleoporin Nup120/160 DNA_pol_A_exo1 PF01612.20 GAP84196.1 - 1.4e-11 44.4 0.0 2.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DUF2528 PF10800.8 GAP84196.1 - 0.089 13.4 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) RNA_pol_L_2 PF13656.6 GAP84197.1 - 2.4e-20 72.1 0.0 3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 GAP84197.1 - 0.00037 19.9 0.0 0.0019 17.6 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Aa_trans PF01490.18 GAP84198.1 - 1.1e-82 278.0 34.5 1.3e-82 277.7 34.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SPT_ssu-like PF11779.8 GAP84198.1 - 2.8 7.7 9.9 1.2 8.8 0.1 4.0 4 0 0 4 4 4 0 Small subunit of serine palmitoyltransferase-like XRN_M PF17846.1 GAP84199.1 - 2.4e-98 330.0 4.9 4.2e-98 329.2 4.9 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 GAP84199.1 - 7.7e-97 323.5 0.0 1.2e-96 322.8 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 GAP84199.1 - 2.3e-75 252.6 0.0 3.9e-75 251.9 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 GAP84199.1 - 1.3e-32 111.8 0.0 3.2e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 GAP84199.1 - 2.6e-23 81.9 0.1 7.4e-23 80.4 0.1 1.9 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 GAP84199.1 - 8.6e-06 25.8 0.1 1.8e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 zf-RanBP PF00641.18 GAP84201.1 - 2.2e-16 58.9 15.3 2.4e-09 36.3 2.9 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 GAP84201.1 - 5.7e-08 32.5 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 GAP84201.1 - 7.4e-06 26.6 0.0 1.1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Pmp3 PF01679.17 GAP84202.1 - 1.3e-20 73.3 6.9 1.6e-20 73.0 6.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator GLEYA PF10528.9 GAP84204.1 - 3.7e-25 88.2 0.1 5.2e-25 87.7 0.1 1.2 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 GAP84204.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 PA14 domain DUF454 PF04304.13 GAP84204.1 - 0.23 11.5 0.2 0.23 11.5 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF454) TMEM52 PF14979.6 GAP84205.1 - 0.06 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Transmembrane 52 HET PF06985.11 GAP84207.1 - 7.1e-26 91.3 0.1 1.5e-25 90.3 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 GAP84207.1 - 1.5e-17 63.7 0.0 4.3e-16 59.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84207.1 - 2.7e-11 43.5 0.0 1e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP84207.1 - 4.8e-08 33.1 0.1 1e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP84207.1 - 6.9e-07 29.0 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP84207.1 - 0.051 13.5 0.2 0.092 12.6 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DUF3425 PF11905.8 GAP84208.1 - 1.9e-18 66.6 0.0 3.9e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) AAA PF00004.29 GAP84209.1 - 4.8e-14 52.9 0.0 1.3e-13 51.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP84209.1 - 0.00013 22.4 0.2 0.00035 21.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAP84209.1 - 0.0034 17.4 0.0 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) CPT PF07931.12 GAP84209.1 - 0.0049 16.7 0.0 0.014 15.2 0.0 1.8 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 GAP84209.1 - 0.0076 16.5 0.2 0.16 12.3 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 GAP84209.1 - 0.062 13.8 0.1 0.19 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAP84209.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Ank_2 PF12796.7 GAP84210.1 - 4e-64 213.2 0.0 5.7e-14 52.5 0.4 5.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP84210.1 - 5.1e-52 167.8 0.1 0.0015 18.8 0.0 10.9 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.6 GAP84210.1 - 1.7e-45 152.8 0.0 1e-08 35.5 0.0 8.1 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 GAP84210.1 - 3.1e-45 150.7 0.9 0.0005 20.4 0.0 11.1 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 GAP84210.1 - 8.1e-43 143.9 1.4 7.2e-09 35.7 0.1 9.8 7 3 4 11 11 11 8 Ankyrin repeats (many copies) FUSC PF04632.12 GAP84210.1 - 1.5 7.2 4.6 2.1 6.8 4.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Amidase PF01425.21 GAP84211.1 - 4.2e-07 29.3 0.0 5e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Amidase ABC2_membrane PF01061.24 GAP84212.1 - 6.8e-38 130.2 17.2 6.8e-38 130.2 17.2 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 GAP84212.1 - 4.5e-24 85.5 0.0 1e-23 84.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 GAP84212.1 - 1.4e-05 25.1 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 GAP84212.1 - 0.00032 19.9 26.7 0.00032 19.9 26.7 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 GAP84212.1 - 0.031 13.7 0.0 0.17 11.3 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAP84212.1 - 0.043 13.6 0.1 0.096 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAP84212.1 - 0.053 13.9 0.3 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 GAP84212.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase PDR_CDR PF06422.12 GAP84212.1 - 2.1 8.3 5.2 0.45 10.5 0.2 2.5 3 0 0 3 3 3 0 CDR ABC transporter hEGF PF12661.7 GAP84212.1 - 3.1 8.6 18.6 8.9 7.1 5.5 4.6 3 0 0 3 3 3 0 Human growth factor-like EGF Melibiase_C PF17801.1 GAP84213.1 - 0.12 12.5 0.0 3.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain NGP1NT PF08153.12 GAP84214.1 - 2e-47 160.6 0.3 3.9e-47 159.6 0.0 1.6 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 GAP84214.1 - 6.5e-17 61.7 0.0 1e-13 51.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 GAP84214.1 - 7.9e-06 25.5 0.0 9.9e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAP84214.1 - 5.4e-05 23.1 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 GAP84214.1 - 0.0096 16.0 0.2 3 7.9 0.1 3.2 2 1 1 3 3 3 1 Dynamin family Arf PF00025.21 GAP84214.1 - 0.044 13.2 0.1 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Na_trans_assoc PF06512.13 GAP84214.1 - 1 9.6 5.0 2.1 8.6 5.0 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated But2 PF09792.9 GAP84215.1 - 1.3e-15 58.1 1.1 2.6e-15 57.1 0.0 2.1 3 0 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain Glyco_hydro_18 PF00704.28 GAP84216.1 - 1.1e-25 91.1 3.8 9.7e-25 87.9 3.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 GAP84216.1 - 5.4e-11 42.3 14.2 2.4e-10 40.2 14.2 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain NHL PF01436.21 GAP84218.1 - 0.0022 18.0 0.1 0.051 13.6 0.0 2.8 3 0 0 3 3 3 1 NHL repeat RNase_II_C_S1 PF18614.1 GAP84218.1 - 0.015 15.3 0.7 0.099 12.6 0.0 2.2 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain Arylesterase PF01731.20 GAP84218.1 - 0.046 13.9 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 0 Arylesterase AMP-binding PF00501.28 GAP84221.1 - 5.2e-29 101.1 0.1 1.9e-11 43.2 0.3 5.3 4 1 1 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 GAP84221.1 - 4.4e-16 58.6 0.0 1.2e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.25 GAP84221.1 - 1.2e-09 38.4 0.0 0.0017 18.6 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site HEPN_MAE_28990 PF18737.1 GAP84221.1 - 0.0049 16.8 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 MAE_28990/MAE_18760-like HEPN AMP-binding PF00501.28 GAP84222.1 - 2.7e-17 62.5 0.1 4e-17 61.9 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAP84222.1 - 2e-11 44.0 0.1 5e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 GAP84222.1 - 6.6e-05 21.8 0.0 0.00011 21.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain GH3 PF03321.13 GAP84222.1 - 0.22 10.3 0.0 0.58 8.9 0.0 1.6 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Abhydrolase_6 PF12697.7 GAP84223.1 - 4.6e-10 40.5 1.1 9.2e-10 39.5 1.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP84223.1 - 1.2e-05 25.1 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP84223.1 - 0.0022 17.0 0.0 0.0033 16.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase SSP160 PF06933.11 GAP84224.1 - 1.7 6.7 6.1 3.1 5.9 6.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WD40 PF00400.32 GAP84227.1 - 6.1e-35 118.6 4.4 2.9e-07 31.0 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP84227.1 - 3.8e-21 75.2 0.0 1.9e-08 34.5 0.0 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAP84227.1 - 8.5e-06 25.8 0.4 0.21 11.4 0.0 3.3 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAP84227.1 - 0.046 12.7 5.4 0.72 8.7 0.3 4.1 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cornichon PF03311.14 GAP84228.1 - 1.7e-50 170.4 12.1 1.9e-50 170.2 12.1 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M24 PF00557.24 GAP84229.1 - 8.1e-48 162.9 0.1 1e-47 162.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 GAP84229.1 - 5.2e-21 74.7 7.9 5.6e-21 74.6 6.3 1.9 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 GAP84229.1 - 9.9e-06 25.5 4.1 9.9e-06 25.5 4.1 2.4 2 0 0 2 2 2 1 MYND finger EGF_CA PF07645.15 GAP84229.1 - 4.3 7.6 9.3 3.5 7.9 1.7 2.8 1 1 1 2 2 2 0 Calcium-binding EGF domain FAD_binding_3 PF01494.19 GAP84230.1 - 8.3e-19 68.0 0.0 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP84230.1 - 3.6e-06 26.4 0.0 7.2e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP84230.1 - 4.1e-05 23.7 0.1 9e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAP84230.1 - 0.0021 17.2 0.0 0.0051 15.9 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 GAP84230.1 - 0.0027 18.2 0.0 0.0075 16.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP84230.1 - 0.0033 17.0 0.0 0.0079 15.8 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAP84230.1 - 0.006 15.3 0.0 0.0088 14.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 GAP84230.1 - 0.033 13.3 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase FAD_oxidored PF12831.7 GAP84230.1 - 0.04 13.3 0.1 0.083 12.2 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAP84230.1 - 0.041 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GAP84230.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 GAP84230.1 - 0.14 11.4 0.0 0.94 8.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family adh_short PF00106.25 GAP84231.1 - 9.9e-31 106.7 0.7 2.1e-25 89.3 0.2 2.2 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84231.1 - 9.9e-22 77.6 1.6 8e-21 74.7 1.6 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP84231.1 - 1.1e-09 38.4 0.1 1.8e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP84231.1 - 4.7e-05 23.0 0.0 7.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAP84231.1 - 0.00034 20.2 0.2 0.00054 19.6 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP84231.1 - 0.0013 18.7 0.8 0.012 15.5 0.2 2.3 2 1 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAP84231.1 - 0.0082 15.6 0.4 0.027 13.9 0.4 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase PEP_hydrolase PF09370.10 GAP84232.1 - 9e-127 421.8 2.0 1e-126 421.6 2.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like UPF0261 PF06792.11 GAP84233.1 - 3.1e-10 39.6 0.0 3.3e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Meiotic_rec114 PF03525.14 GAP84233.1 - 0.19 10.7 0.0 0.2 10.6 0.0 1.0 1 0 0 1 1 1 0 Meiotic recombination protein rec114 UPF0261 PF06792.11 GAP84234.1 - 9e-114 380.5 0.2 1e-113 380.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) SR-25 PF10500.9 GAP84234.1 - 2.4 7.7 7.0 3.5 7.2 7.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 GAP84234.1 - 2.5 8.4 6.9 3.9 7.8 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) WD40 PF00400.32 GAP84236.1 - 5.2e-42 141.0 32.1 8.6e-06 26.4 0.7 11.0 11 0 0 11 11 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP84236.1 - 5e-20 71.6 0.3 0.0011 19.2 0.0 8.8 4 4 3 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain NACHT_N PF17100.5 GAP84236.1 - 2.2e-10 40.8 0.0 4.5e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 GAP84236.1 - 1.3e-08 35.0 0.2 2.9e-08 33.8 0.2 1.6 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 GAP84236.1 - 6.5e-05 22.0 1.7 12 4.8 0.0 5.5 3 2 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 GAP84236.1 - 0.00074 19.9 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP84236.1 - 0.0047 17.2 0.1 0.032 14.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain Nup160 PF11715.8 GAP84236.1 - 0.012 14.3 3.8 0.13 10.9 0.0 4.1 6 0 0 6 6 6 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 GAP84236.1 - 0.084 12.4 0.0 13 5.3 0.0 3.8 5 0 0 5 5 5 0 PQQ-like domain Nbas_N PF15492.6 GAP84236.1 - 0.085 12.2 0.1 5.2 6.3 0.0 3.1 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 GAP84236.1 - 0.093 12.7 0.0 4.6 7.3 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF2075 PF09848.9 GAP84236.1 - 0.17 11.1 1.3 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 GAP84236.1 - 0.17 11.1 1.4 0.33 10.1 0.7 1.7 2 0 0 2 2 2 0 KAP family P-loop domain GATase_5 PF13507.6 GAP84237.1 - 7.3e-97 323.5 0.0 1.1e-96 323.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 GAP84237.1 - 5.7e-33 114.3 0.0 6.3e-21 75.1 0.1 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 GAP84237.1 - 1.4e-22 79.9 0.0 2.8e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 GAP84237.1 - 1.5e-20 73.5 0.0 3.7e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Abhydrolase_1 PF00561.20 GAP84238.1 - 5.8e-08 32.7 0.0 8.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP84238.1 - 9.8e-07 29.6 0.6 9.8e-07 29.6 0.6 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP84238.1 - 0.033 13.4 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cupin_2 PF07883.11 GAP84239.1 - 3.1e-14 52.4 0.2 4.5e-14 51.9 0.2 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 GAP84239.1 - 8.2e-05 22.2 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 GAP84239.1 - 0.00016 21.6 0.2 0.00021 21.2 0.2 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 GAP84239.1 - 0.00063 19.4 0.0 0.00087 18.9 0.0 1.2 1 0 0 1 1 1 1 Cupin GPI PF06560.11 GAP84239.1 - 0.011 15.1 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) ARD PF03079.14 GAP84239.1 - 0.048 13.9 0.1 0.068 13.3 0.1 1.1 1 0 0 1 1 1 0 ARD/ARD' family DUF3506 PF12014.8 GAP84240.1 - 4.8e-55 185.4 0.0 6.9e-55 184.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) DUF1769 PF08588.10 GAP84241.1 - 7.1e-27 93.4 1.1 2.2e-26 91.8 1.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Ada3 PF10198.9 GAP84242.1 - 3.4e-52 176.1 0.8 6.8e-52 175.1 0.0 1.9 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Amidohydro_1 PF01979.20 GAP84243.1 - 2.1e-73 247.6 0.6 4.6e-73 246.5 0.3 1.6 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 GAP84243.1 - 1.5e-55 186.7 2.1 2.9e-55 185.8 2.1 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 GAP84243.1 - 1.9e-40 137.2 0.7 3.7e-40 136.2 0.1 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Urease_beta PF00699.20 GAP84243.1 - 8.2e-40 134.8 0.2 6.4e-39 131.9 0.0 2.3 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 GAP84243.1 - 8.4e-11 42.0 2.3 3.7e-07 30.0 0.8 2.5 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 GAP84243.1 - 0.012 15.4 0.2 0.057 13.2 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase HMG_box PF00505.19 GAP84244.1 - 3.1e-07 30.7 0.1 7.1e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAP84244.1 - 5.5e-05 23.7 0.1 0.00026 21.5 0.1 2.2 2 0 0 2 2 2 1 HMG-box domain Het-C PF07217.11 GAP84245.1 - 1.1e-233 776.9 0.0 1.4e-233 776.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.18 GAP84245.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Zinc dependent phospholipase C Glyco_hydro_45 PF02015.16 GAP84246.1 - 2.2e-71 240.1 19.2 2.7e-71 239.8 19.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 GMC_oxred_C PF05199.13 GAP84247.1 - 1.4e-15 58.1 0.0 3.8e-15 56.7 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 GAP84247.1 - 2e-07 30.7 0.1 1.4e-05 24.6 0.0 2.6 3 0 0 3 3 3 1 GMC oxidoreductase ApbA PF02558.16 GAP84247.1 - 2.2e-05 24.2 0.1 4.8e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 GAP84247.1 - 2.9e-05 23.5 0.0 0.0056 15.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAP84247.1 - 0.00012 21.5 0.1 0.00022 20.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 GAP84247.1 - 0.0023 17.9 0.1 0.0039 17.1 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 GAP84247.1 - 0.0023 18.1 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 GAP84247.1 - 0.006 16.2 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 GAP84247.1 - 0.025 13.9 0.1 0.052 12.9 0.1 1.5 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.27 GAP84247.1 - 0.035 14.6 0.1 0.091 13.3 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAP84247.1 - 0.071 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 GAP84247.1 - 0.083 11.6 0.1 0.16 10.7 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.6 GAP84247.1 - 0.091 13.2 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 GAP84247.1 - 0.13 11.7 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fructosamin_kin PF03881.14 GAP84249.1 - 2.1e-11 43.6 0.0 8.2e-11 41.6 0.0 1.7 1 1 1 2 2 2 1 Fructosamine kinase HET PF06985.11 GAP84250.1 - 7.5e-27 94.5 0.0 2.9e-26 92.6 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 GAP84251.1 - 8.3e-26 91.1 0.3 1.4e-25 90.4 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Surp PF01805.20 GAP84251.1 - 0.0061 16.5 0.1 0.016 15.2 0.1 1.7 1 0 0 1 1 1 1 Surp module DAO PF01266.24 GAP84252.1 - 5.9e-28 98.4 0.0 7.2e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP84252.1 - 1.3e-07 31.1 0.0 1.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP84252.1 - 0.00025 20.4 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP84252.1 - 0.00048 20.3 0.2 0.0014 18.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAP84252.1 - 0.0056 15.8 0.2 0.0084 15.2 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 GAP84252.1 - 0.0067 15.2 0.5 0.0089 14.8 0.5 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAP84252.1 - 0.012 14.8 0.3 0.018 14.3 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP84252.1 - 0.02 14.2 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 GAP84252.1 - 0.022 15.3 1.0 0.053 14.1 0.6 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAP84252.1 - 0.025 14.2 1.7 0.028 14.1 0.1 2.0 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 GAP84252.1 - 0.054 14.1 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 GAP84252.1 - 0.11 11.7 0.2 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAP84252.1 - 0.12 11.5 0.2 0.16 11.0 0.2 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 GAP84252.1 - 0.12 11.9 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 GAP84252.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Acyl-CoA_dh_1 PF00441.24 GAP84253.1 - 5.7e-30 104.5 5.9 1.2e-29 103.5 5.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAP84253.1 - 1.9e-22 79.3 0.3 3.2e-22 78.5 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAP84253.1 - 2.2e-21 76.6 0.0 7e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAP84253.1 - 0.00081 19.7 2.4 0.00081 19.7 2.4 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain MMM1 PF10296.9 GAP84254.1 - 1.1e-05 24.7 0.0 4.8e-05 22.6 0.0 2.0 2 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PRR18 PF15671.5 GAP84254.1 - 0.13 12.1 17.5 0.1 12.4 14.7 2.3 2 1 0 2 2 2 0 Proline-rich protein family 18 CYSTM PF12734.7 GAP84254.1 - 0.43 10.9 2.7 1.2 9.6 2.7 1.8 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance SARAF PF06682.12 GAP84254.1 - 4.4 6.9 6.7 1.4 8.5 0.0 2.4 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis MCM2_N PF12619.8 GAP84254.1 - 9.6 6.5 20.3 2.2 8.6 3.1 2.8 3 0 0 3 3 3 0 Mini-chromosome maintenance protein 2 PIP5K PF01504.18 GAP84255.1 - 7.1e-35 120.6 0.9 5.4e-26 91.4 1.3 2.9 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 GAP84255.1 - 6.5e-26 91.0 0.0 1e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 GAP84255.1 - 9.4e-13 48.1 11.3 3e-12 46.5 10.8 2.1 2 0 0 2 2 2 1 FYVE zinc finger DUF4486 PF14858.6 GAP84255.1 - 0.26 9.7 1.5 0.37 9.2 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4486) FYVE_2 PF02318.16 GAP84255.1 - 2.3 8.4 9.7 0.31 11.2 3.9 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger AMP-binding PF00501.28 GAP84257.1 - 3.8e-67 226.7 0.0 3.7e-34 118.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 GAP84257.1 - 5.5e-10 40.1 0.0 1.8e-09 38.4 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.18 GAP84258.1 - 1.1e-55 187.8 0.2 1.4e-55 187.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Methyltransf_16 PF10294.9 GAP84259.1 - 1.8e-15 57.1 0.0 3.7e-14 52.8 0.0 2.1 1 1 1 2 2 2 1 Lysine methyltransferase 2OG-FeII_Oxy_3 PF13640.6 GAP84259.1 - 3.4e-12 47.1 0.0 6.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_12 PF08242.12 GAP84259.1 - 0.0085 16.8 0.0 0.041 14.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP84259.1 - 0.11 13.3 0.0 0.37 11.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAP84259.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAP84259.1 - 0.13 12.9 0.0 0.29 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAP84259.1 - 0.15 11.6 0.1 0.94 9.0 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase small domain APH PF01636.23 GAP84261.1 - 1.7e-14 54.4 0.0 2.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP84261.1 - 0.0002 21.0 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Sugar_tr PF00083.24 GAP84262.1 - 1.5e-106 356.9 18.1 1.7e-106 356.8 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP84262.1 - 1e-27 97.0 54.3 9.5e-24 84.0 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAP84262.1 - 0.00036 18.9 0.9 0.00065 18.1 0.9 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.8 GAP84263.1 - 1.5e-19 70.1 3.0 3.1e-19 69.1 3.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 GAP84264.1 - 8.3e-23 80.9 0.2 9.9e-23 80.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84264.1 - 5e-20 72.1 0.1 6.4e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP84264.1 - 5.3e-09 36.2 0.1 7.7e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP84264.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAP84264.1 - 0.069 12.1 0.0 0.19 10.7 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAP84264.1 - 0.18 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Transketolase_N PF00456.21 GAP84265.1 - 3.8e-124 414.0 0.0 6.7e-124 413.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAP84265.1 - 2.2e-39 135.0 0.1 1.6e-38 132.2 0.0 2.4 3 0 0 3 3 3 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 GAP84265.1 - 1.6e-09 37.4 0.0 3.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 GAP84265.1 - 1.9e-05 24.6 0.0 5.8e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 GAP84265.1 - 7.1e-05 21.9 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 GAP84265.1 - 0.00047 20.0 4.6 0.0095 15.7 0.7 3.7 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Borrelia_P13 PF05628.12 GAP84265.1 - 0.062 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Borrelia membrane protein P13 Peptidase_C14 PF00656.22 GAP84266.1 - 7.5e-21 75.2 0.0 1.3e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 GAP84266.1 - 0.1 12.1 0.0 0.53 9.7 0.0 2.0 2 0 0 2 2 2 0 Peptidase C13 family DUF4252 PF14060.6 GAP84266.1 - 0.21 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Actin PF00022.19 GAP84268.1 - 5.9e-144 479.6 0.0 6.7e-144 479.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 GAP84268.1 - 1.1e-06 27.8 0.1 0.012 14.4 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein D-ser_dehydrat PF14031.6 GAP84269.1 - 5.7e-24 84.6 0.1 1.2e-23 83.6 0.1 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 GAP84269.1 - 9.3e-07 28.7 0.1 1.9e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain Foamy_virus_ENV PF03408.14 GAP84269.1 - 0.022 12.6 0.0 0.029 12.2 0.0 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein Sporozoite_P67 PF05642.11 GAP84269.1 - 0.27 9.3 1.5 0.37 8.8 1.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen THOC2_N PF16134.5 GAP84269.1 - 0.4 9.2 2.5 0.55 8.8 2.5 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus TSGP1 PF07771.11 GAP84269.1 - 0.9 9.7 9.3 1.8 8.8 9.3 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 CDC45 PF02724.14 GAP84269.1 - 5 5.3 4.9 6.8 4.9 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 GAP84269.1 - 5.4 7.5 11.1 10 6.5 11.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HMG-CoA_red PF00368.18 GAP84270.1 - 4.5e-137 457.0 7.7 5.9e-137 456.6 7.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 GAP84270.1 - 8.7e-48 162.1 0.3 1.4e-47 161.5 0.3 1.3 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 GAP84270.1 - 3.9e-12 46.3 7.5 9.4e-11 41.8 7.5 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 GAP84270.1 - 3.1e-08 32.2 0.4 3.1e-08 32.2 0.4 1.6 2 0 0 2 2 2 1 Patched family Isochorismatase PF00857.20 GAP84272.1 - 3.4e-14 53.4 0.0 8.6e-14 52.1 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family Abhydrolase_3 PF07859.13 GAP84273.1 - 1.7e-25 90.1 0.1 2.2e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP84273.1 - 4.1e-13 48.9 0.0 8.2e-12 44.7 0.0 2.1 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 GAP84273.1 - 0.00096 18.1 0.1 0.0051 15.7 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family DHquinase_II PF01220.19 GAP84274.1 - 1.3e-59 199.8 0.1 1.4e-59 199.7 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II TetR_C_11 PF16859.5 GAP84274.1 - 0.058 13.7 0.8 0.1 12.9 0.7 1.4 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3844 PF12955.7 GAP84276.1 - 8.4e-38 128.7 4.2 8.4e-38 128.7 4.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) TMF_TATA_bd PF12325.8 GAP84277.1 - 0.73 10.1 3.3 1.1 9.4 0.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding LSM PF01423.22 GAP84278.1 - 1.1e-21 76.3 0.5 1.2e-21 76.2 0.5 1.0 1 0 0 1 1 1 1 LSM domain Glyco_hydro_76 PF03663.14 GAP84279.1 - 5.8e-131 437.3 1.4 6.7e-131 437.1 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 GvpL_GvpF PF06386.11 GAP84280.1 - 0.036 14.0 3.3 0.057 13.3 3.3 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Caudo_TAP PF02413.17 GAP84280.1 - 0.18 12.0 6.3 0.11 12.7 4.0 1.8 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Glyco_tranf_2_3 PF13641.6 GAP84281.1 - 6e-25 88.5 0.0 7.9e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 GAP84281.1 - 4.7e-06 26.2 0.0 1e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAP84281.1 - 1.7e-05 24.7 0.0 2.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Meth_synt_2 PF01717.18 GAP84282.1 - 1.5e-05 24.5 0.0 7.8e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain YrhK PF14145.6 GAP84283.1 - 0.19 11.6 26.3 0.66 9.9 0.2 4.9 3 2 1 4 4 4 0 YrhK-like protein Phage_holin_4_2 PF04020.13 GAP84283.1 - 1.5 9.5 6.8 0.46 11.2 0.7 2.4 2 0 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV Pkinase PF00069.25 GAP84284.1 - 1.3e-62 211.6 0.0 2.2e-62 210.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84284.1 - 2e-35 122.3 0.0 5.2e-30 104.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAP84284.1 - 5.3e-08 32.5 0.0 0.00013 21.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 GAP84284.1 - 0.0015 18.5 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAP84284.1 - 0.025 13.5 0.1 0.039 12.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 GAP84284.1 - 0.029 14.0 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 GAP84284.1 - 0.094 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Levi_coat PF01819.17 GAP84284.1 - 0.45 10.5 2.1 0.83 9.7 0.3 2.3 3 0 0 3 3 3 0 Levivirus coat protein DAHP_synth_2 PF01474.16 GAP84285.1 - 2.3e-204 678.9 0.0 2.6e-204 678.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family p450 PF00067.22 GAP84287.1 - 2.4e-48 165.1 0.0 2.8e-47 161.5 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Na_Ca_ex PF01699.24 GAP84288.1 - 6.2e-38 130.1 38.6 1.7e-20 73.5 19.1 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SPT6_acidic PF14632.6 GAP84288.1 - 0.27 11.9 4.6 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 PI3K_1B_p101 PF10486.9 GAP84288.1 - 2.2 6.0 5.5 3.4 5.3 5.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SPRY PF00622.28 GAP84289.1 - 4.5e-07 30.0 0.0 6.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain ANAPC4_WD40 PF12894.7 GAP84290.1 - 6.8e-10 39.1 0.0 0.00073 19.8 0.0 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_6 PF12697.7 GAP84290.1 - 5.6e-08 33.7 0.2 2.2e-07 31.7 0.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 GAP84290.1 - 2.3e-05 24.0 0.0 5.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) WD40 PF00400.32 GAP84290.1 - 2.8e-05 24.8 2.6 0.22 12.5 0.0 6.2 6 0 0 6 6 6 1 WD domain, G-beta repeat PGAP1 PF07819.13 GAP84290.1 - 5.3e-05 23.0 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.12 GAP84290.1 - 0.0001 22.3 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 GAP84290.1 - 0.021 14.1 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 GAP84290.1 - 0.03 14.7 0.0 0.083 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Frtz PF11768.8 GAP84290.1 - 0.059 11.7 0.0 0.11 10.8 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz NB-ARC PF00931.22 GAP84290.1 - 0.14 11.3 0.0 0.43 9.7 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain Beta_helix PF13229.6 GAP84291.1 - 0.00011 22.1 23.4 0.011 15.6 16.2 2.4 1 1 1 2 2 2 2 Right handed beta helix region Fructosamin_kin PF03881.14 GAP84292.1 - 4.4e-26 91.7 0.0 5.6e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 GAP84292.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family ADH_N PF08240.12 GAP84293.1 - 5.1e-28 97.1 3.1 6.9e-28 96.7 1.6 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP84293.1 - 2e-14 53.7 0.0 2.8e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAP84293.1 - 0.00024 20.7 0.9 0.0077 15.7 0.9 2.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ATP-synt_G PF04718.15 GAP84294.1 - 1.7e-32 112.2 2.8 4.5e-32 110.8 0.5 2.1 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit SipA_VBS PF17985.1 GAP84294.1 - 0.05 13.5 0.1 0.05 13.5 0.1 2.9 3 0 0 3 3 3 0 SipA vinculin binding site Methyltransf_23 PF13489.6 GAP84295.1 - 1.5e-16 60.6 0.0 2.2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP84295.1 - 1.6e-11 44.7 0.0 4.3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP84295.1 - 2.1e-08 34.1 0.0 3.4e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP84295.1 - 2.5e-07 31.3 0.0 5.9e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP84295.1 - 7.3e-05 23.4 0.1 0.00075 20.2 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 GAP84295.1 - 0.0031 17.6 0.0 0.0045 17.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 GAP84295.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 GAP84295.1 - 0.031 13.6 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family TFIIA PF03153.13 GAP84297.1 - 2.1e-90 304.7 10.5 2.4e-90 304.5 10.5 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ANAPC4_WD40 PF12894.7 GAP84298.1 - 2.5e-17 63.0 3.9 3.5e-05 24.0 0.1 4.3 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAP84298.1 - 1.5e-15 57.3 17.9 0.00033 21.4 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAP84298.1 - 5.2e-06 25.7 0.0 0.00034 19.7 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAP84298.1 - 6.6e-06 26.1 0.4 0.001 19.0 0.2 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.6 GAP84299.1 - 2.3e-28 97.9 6.2 4.9e-08 32.8 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 GAP84299.1 - 6.6e-24 83.4 2.4 4.3e-06 26.6 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 GAP84299.1 - 4.1e-22 77.6 4.0 0.00016 21.8 0.0 5.0 2 1 2 4 4 4 4 Kelch motif Kelch_3 PF13415.6 GAP84299.1 - 4.4e-20 71.5 2.1 8.7e-07 29.1 0.1 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAP84299.1 - 1.7e-18 65.9 0.2 7.5e-05 22.2 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 GAP84299.1 - 2.2e-17 62.3 2.6 0.00023 21.0 0.0 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 GAP84299.1 - 1.3e-09 38.2 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 GAP84299.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 BTB And C-terminal Kelch zf-C2H2_aberr PF17017.5 GAP84300.1 - 0.022 14.9 0.0 0.022 14.9 0.0 2.4 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 GAP84300.1 - 0.027 15.3 19.1 0.85 10.6 5.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAP84300.1 - 0.031 14.7 18.9 0.081 13.4 0.7 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP84300.1 - 0.034 14.6 2.5 0.034 14.6 2.5 3.6 4 0 0 4 4 4 0 Zinc-finger double domain zf-CHCC PF10276.9 GAP84300.1 - 0.21 11.7 0.9 0.45 10.6 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger domain zf-BED PF02892.15 GAP84300.1 - 2.7 8.1 8.7 0.93 9.6 0.8 3.0 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_jaz PF12171.8 GAP84300.1 - 4.4 7.7 10.4 7.8 6.9 3.3 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HIG_1_N PF04588.13 GAP84301.1 - 1.7e-06 28.1 1.1 1.7e-06 28.1 1.1 2.0 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Romo1 PF10247.9 GAP84301.1 - 2.3 8.7 7.2 1 9.8 4.4 1.8 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Kelch_5 PF13854.6 GAP84302.1 - 7.5e-41 137.5 12.9 3e-06 27.1 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 GAP84302.1 - 7.9e-38 128.2 16.3 6e-08 32.6 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 GAP84302.1 - 1.4e-36 123.8 16.6 2.6e-08 33.3 0.5 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAP84302.1 - 5.7e-36 122.1 13.7 4.3e-09 36.4 0.0 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 GAP84302.1 - 8.6e-29 98.9 15.7 4e-07 30.1 0.0 6.6 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.15 GAP84302.1 - 1.3e-26 91.5 18.2 1.6e-05 24.6 0.2 6.6 6 1 0 6 6 6 6 Kelch motif Dus PF01207.17 GAP84303.1 - 9.1e-38 130.1 0.0 6.4e-28 97.7 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 GAP84303.1 - 0.26 11.4 7.6 0.93 9.6 1.1 2.8 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 GAP84303.1 - 9.4 6.3 8.5 18 5.4 1.5 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bap31 PF05529.12 GAP84304.1 - 1.9e-48 163.8 10.0 2.4e-48 163.4 10.0 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 GAP84304.1 - 3.8e-15 55.6 0.6 3.8e-15 55.6 0.6 1.9 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain TRAF_BIRC3_bd PF16673.5 GAP84304.1 - 0.034 13.9 0.6 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF2730 PF10805.8 GAP84304.1 - 0.044 13.9 0.2 0.08 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) RE_HaeIII PF09556.10 GAP84304.1 - 0.049 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease V_ATPase_I PF01496.19 GAP84304.1 - 0.088 10.7 0.5 0.14 10.1 0.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Wtap PF17098.5 GAP84304.1 - 0.097 12.6 1.2 0.17 11.8 1.2 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family Lebercilin PF15619.6 GAP84304.1 - 0.1 12.3 3.1 0.15 11.7 3.1 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Cep57_MT_bd PF06657.13 GAP84304.1 - 0.15 12.5 2.6 4.2 7.9 2.6 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6_N PF17675.1 GAP84304.1 - 0.24 12.0 3.2 0.46 11.0 3.2 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region GPS2_interact PF15784.5 GAP84304.1 - 0.35 11.3 4.8 0.82 10.1 4.4 1.8 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Csm1_N PF18504.1 GAP84304.1 - 0.43 10.9 3.7 1.1 9.7 2.5 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain DivIC PF04977.15 GAP84304.1 - 0.69 9.7 8.7 0.52 10.1 1.1 3.3 2 2 1 3 3 3 0 Septum formation initiator DUF4337 PF14235.6 GAP84304.1 - 1 9.5 3.3 1.9 8.6 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BRE1 PF08647.11 GAP84304.1 - 2 8.6 6.3 13 5.9 6.4 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1479 PF07350.12 GAP84305.1 - 2.5e-147 491.0 0.0 2.5e-128 428.4 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) Glyco_hydro_99 PF16317.5 GAP84306.1 - 0.02 14.1 0.0 0.34 10.0 0.0 2.2 2 1 0 2 2 2 0 Glycosyl hydrolase family 99 HHH PF00633.23 GAP84307.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-met2 PF12907.7 GAP84308.1 - 1.9e-15 56.7 1.3 3.2e-15 56.0 1.3 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 GAP84308.1 - 5e-07 30.5 12.7 9.6e-07 29.6 12.7 1.4 1 0 0 1 1 1 1 4F5 protein family DUF382 PF04037.13 GAP84308.1 - 0.062 13.5 0.3 0.076 13.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF382) DIOX_N PF14226.6 GAP84309.1 - 3.1e-33 115.0 0.0 1.2e-31 109.9 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP84309.1 - 2.3e-13 50.5 0.0 4.6e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 GAP84310.1 - 1.7e-09 38.1 9.7 0.0012 19.6 0.2 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP84310.1 - 0.00085 19.6 0.1 3.4 8.0 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PPK2 PF03976.14 GAP84310.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) RNA_pol_N PF01194.17 GAP84311.1 - 6.7e-30 103.2 0.6 7.9e-30 102.9 0.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 GAP84311.1 - 0.1 12.9 0.5 0.23 11.7 0.5 1.6 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) XK-related PF09815.9 GAP84312.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 XK-related protein Cu_bind_CorA PF18252.1 GAP84312.1 - 0.056 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Copper(I)-binding protein CorA Helo_like_N PF17111.5 GAP84312.1 - 0.057 12.8 0.3 0.75 9.1 0.0 2.4 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Myb_DNA-binding PF00249.31 GAP84314.1 - 0.0017 18.5 0.2 0.017 15.3 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP84314.1 - 0.075 13.3 0.6 2.1 8.7 0.0 3.2 2 1 1 3 3 3 0 Myb-like DNA-binding domain Methyltransf_16 PF10294.9 GAP84315.1 - 2.1e-24 86.2 0.0 4.5e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAP84315.1 - 0.00058 19.7 0.0 0.00086 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP84315.1 - 0.012 16.3 0.0 0.11 13.2 0.0 2.7 3 1 0 3 3 3 0 Methyltransferase domain PrmA PF06325.13 GAP84315.1 - 0.037 13.4 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 GAP84315.1 - 0.078 12.8 0.0 0.47 10.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAP84315.1 - 0.11 12.1 0.1 0.37 10.3 0.1 1.7 1 1 1 2 2 2 0 Methyltransferase small domain pPIWI_RE_REase PF18154.1 GAP84315.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 REase associating with pPIWI_RE Dynein_light PF01221.18 GAP84318.1 - 1.1e-40 137.8 1.1 1.2e-40 137.7 1.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.22 GAP84319.1 - 8e-75 246.6 1.6 1.3e-16 60.2 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAP84319.1 - 3.6e-12 46.0 0.0 0.017 14.9 0.0 5.3 5 0 0 5 5 5 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GAP84319.1 - 8.3e-10 38.5 0.0 0.035 14.1 0.0 4.6 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 GAP84319.1 - 1.1e-09 38.2 0.0 0.0099 15.9 0.0 4.4 3 1 0 3 3 3 3 Limkain b1 RRM_3 PF08777.11 GAP84319.1 - 1.4e-08 34.7 0.5 0.41 10.7 0.0 4.9 5 0 0 5 5 5 3 RNA binding motif RRM_7 PF16367.5 GAP84319.1 - 1.1e-07 31.9 0.0 0.24 11.5 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif RRM_5 PF13893.6 GAP84319.1 - 5.4e-05 22.8 0.0 0.1 12.2 0.0 3.7 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 GAP84319.1 - 0.00011 21.7 0.1 21 4.9 0.0 4.9 4 1 0 4 4 4 0 Histone lysine methyltransferase SET associated PHM7_cyt PF14703.6 GAP84319.1 - 0.00067 19.9 5.0 4.7 7.4 0.0 6.7 5 3 3 8 8 8 1 Cytosolic domain of 10TM putative phosphate transporter Smg4_UPF3 PF03467.15 GAP84319.1 - 0.043 13.8 1.3 0.69 9.9 1.3 2.7 1 1 0 1 1 1 0 Smg-4/UPF3 family WW_like PF17890.1 GAP84319.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain TEA PF01285.18 GAP84320.1 - 3.4e-21 75.1 1.1 1.2e-20 73.4 0.1 2.4 2 0 0 2 2 2 1 TEA/ATTS domain ATG16 PF08614.11 GAP84321.1 - 0.0042 17.4 24.5 0.0042 17.4 24.5 5.2 2 1 1 4 4 4 2 Autophagy protein 16 (ATG16) Spc7 PF08317.11 GAP84321.1 - 0.0043 16.0 20.3 0.0043 16.0 20.3 5.5 2 1 2 5 5 5 2 Spc7 kinetochore protein DUF2856 PF11043.8 GAP84321.1 - 1.2 9.3 7.4 3.4 7.8 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) BRE1 PF08647.11 GAP84321.1 - 4.6 7.4 0.0 4.6 7.4 0.0 8.6 3 1 5 8 8 8 0 BRE1 E3 ubiquitin ligase TPR_12 PF13424.6 GAP84322.1 - 2.2e-07 31.1 12.2 0.00029 21.1 4.7 3.8 2 1 3 5 5 5 3 Tetratricopeptide repeat HET PF06985.11 GAP84322.1 - 1.3e-06 28.9 0.0 7.3e-05 23.2 0.0 2.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.6 GAP84322.1 - 7.5e-05 22.5 11.6 0.014 15.2 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAP84322.1 - 0.00071 20.2 14.5 8.3 7.5 0.7 6.9 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAP84322.1 - 0.095 12.1 12.4 0.1 11.9 10.3 1.8 1 1 1 2 2 2 0 MalT-like TPR region VCBS PF13517.6 GAP84323.1 - 2.6e-07 31.1 5.4 0.00055 20.5 1.9 3.6 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAP84323.1 - 2.4e-05 24.4 3.9 0.032 14.4 0.4 3.6 3 0 0 3 3 3 2 FG-GAP repeat EF-hand_6 PF13405.6 GAP84323.1 - 0.00011 21.8 0.8 1.5 8.9 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain P_proprotein PF01483.20 GAP84323.1 - 0.00049 20.1 0.9 14 5.8 0.1 4.0 3 1 1 4 4 4 1 Proprotein convertase P-domain EF-hand_1 PF00036.32 GAP84323.1 - 0.0006 19.2 0.3 0.8 9.4 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 GAP84323.1 - 0.021 14.3 3.4 6.2 6.5 0.1 3.4 3 0 0 3 3 3 0 EF hand DUF756 PF05506.12 GAP84323.1 - 0.085 13.8 1.4 5.7 7.9 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF756) PNP_UDP_1 PF01048.20 GAP84324.1 - 1e-06 28.2 1.0 6.7e-06 25.5 1.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Glyco_transf_90 PF05686.12 GAP84327.1 - 7e-07 28.5 1.1 0.00066 18.7 0.3 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 90 T_cell_tran_alt PF15128.6 GAP84327.1 - 0.17 11.7 1.3 17 5.3 0.3 2.9 2 0 0 2 2 2 0 T-cell leukemia translocation-altered PX PF00787.24 GAP84328.1 - 4.2e-19 68.6 0.2 1.2e-18 67.1 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 GAP84328.1 - 5.8e-07 29.3 11.1 0.00012 21.7 1.6 2.3 2 0 0 2 2 2 2 Vps5 C terminal like Snapin_Pallidin PF14712.6 GAP84328.1 - 0.22 12.0 5.1 9.2 6.8 0.1 3.3 2 1 1 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.12 GAP84328.1 - 1.2 9.2 5.5 3.7 7.6 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TerB PF05099.13 GAP84328.1 - 5.5 6.9 9.0 1.1 9.3 1.7 2.8 3 0 0 3 3 3 0 Tellurite resistance protein TerB K_channel_TID PF07941.11 GAP84329.1 - 0.01 16.2 5.6 0.01 16.2 5.6 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Peptidase_S8 PF00082.22 GAP84330.1 - 1.2e-33 116.7 1.4 1.9e-33 116.0 1.4 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 GAP84330.1 - 2.3e-26 91.6 1.4 5.1e-26 90.5 1.4 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 GAP84330.1 - 2e-05 25.3 0.2 5.2e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 GAP84330.1 - 0.15 12.5 0.0 0.65 10.5 0.0 2.0 1 1 1 2 2 2 0 N-terminal of Subtilase family Glyco_hydro_47 PF01532.20 GAP84332.1 - 5e-113 378.4 0.0 6.8e-113 378.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PD-C2-AF1 PF09310.10 GAP84332.1 - 0.026 13.9 0.1 0.047 13.1 0.1 1.3 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 Myb_DNA-binding PF00249.31 GAP84333.1 - 0.0024 18.0 0.5 0.41 10.9 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP84333.1 - 0.056 13.7 4.3 2.1 8.7 0.4 3.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain RRS1 PF04939.12 GAP84333.1 - 3.3 7.6 9.2 0.43 10.4 3.3 2.3 1 1 1 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) Fungal_trans PF04082.18 GAP84335.1 - 0.0012 17.9 0.9 0.0024 16.9 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP84335.1 - 0.06 13.5 10.8 0.13 12.4 1.9 2.6 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain IclR PF01614.18 GAP84335.1 - 0.14 12.0 0.2 0.51 10.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial transcriptional regulator Cytochrom_B562 PF07361.11 GAP84335.1 - 0.53 11.0 2.6 0.72 10.5 0.1 2.3 3 0 0 3 3 3 0 Cytochrome b562 Cupin_2 PF07883.11 GAP84337.1 - 3.5e-10 39.4 0.6 3.2e-05 23.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 GAP84337.1 - 1.6e-06 27.8 0.1 1.9e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.12 GAP84337.1 - 0.0032 17.1 0.1 0.013 15.2 0.1 1.8 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_3 PF05899.12 GAP84337.1 - 0.053 13.2 0.0 0.25 11.1 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF861) NmrA PF05368.13 GAP84338.1 - 1.2e-59 201.8 0.0 1.4e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP84338.1 - 1.3e-20 74.0 0.0 2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAP84338.1 - 4e-07 29.3 0.0 5.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAP84338.1 - 0.00021 20.8 0.1 0.00042 19.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAP84338.1 - 0.0013 19.0 0.1 0.0021 18.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 GAP84338.1 - 0.035 13.7 0.7 0.064 12.8 0.6 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Peroxin-13_N PF04088.13 GAP84339.1 - 3e-51 173.5 0.0 4.5e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 GAP84339.1 - 4.1e-08 32.8 0.0 9.7e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAP84339.1 - 1.8e-07 30.7 0.0 3.8e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAP84339.1 - 1.1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 GAP84339.1 - 0.26 11.7 0.0 0.44 11.0 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain TraT PF05818.12 GAP84339.1 - 7.3 6.2 6.5 17 5.0 6.5 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein tRNA-synt_2 PF00152.20 GAP84340.1 - 2.9e-87 292.7 0.0 4e-87 292.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 GAP84340.1 - 0.00011 22.2 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 GAP84340.1 - 0.01 15.3 0.0 0.077 12.5 0.1 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) ANTH PF07651.16 GAP84341.1 - 2.4e-64 217.0 0.3 3e-64 216.7 0.3 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 GAP84341.1 - 5.6e-07 29.6 0.0 8.8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain MAT1 PF06391.13 GAP84342.1 - 4.3e-31 108.3 4.2 6.1e-31 107.8 4.2 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 GAP84342.1 - 1.6e-26 91.9 9.8 2.7e-26 91.2 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP84342.1 - 0.0026 17.6 7.8 0.0063 16.4 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 GAP84342.1 - 0.018 15.2 1.8 0.036 14.2 1.8 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger MRP-S26 PF14943.6 GAP84342.1 - 0.058 13.3 12.2 0.12 12.3 12.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 eIF-3_zeta PF05091.12 GAP84342.1 - 0.065 12.2 1.1 0.084 11.8 1.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf-RING_6 PF14835.6 GAP84342.1 - 0.067 13.1 4.4 0.15 11.9 3.8 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 GAP84342.1 - 0.088 13.2 6.8 0.2 12.0 6.8 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 GAP84342.1 - 0.093 12.6 6.0 0.21 11.5 6.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP84342.1 - 0.63 10.1 6.3 1.5 8.9 6.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 GAP84342.1 - 0.72 9.9 9.4 4.2 7.4 9.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain DUF1682 PF07946.14 GAP84342.1 - 1.7 7.7 8.8 2.5 7.2 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MAS20 PF02064.15 GAP84342.1 - 2.7 8.1 9.2 4.8 7.3 9.2 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor zf-RING_4 PF14570.6 GAP84342.1 - 5 7.0 8.9 35 4.3 9.4 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain CS PF04969.16 GAP84343.1 - 4.8e-15 56.3 0.1 1.1e-14 55.2 0.0 1.6 2 0 0 2 2 2 1 CS domain RL10P_insert PF17777.1 GAP84343.1 - 0.022 14.7 0.3 0.07 13.1 0.1 1.9 2 0 0 2 2 2 0 Insertion domain in 60S ribosomal protein L10P Prefoldin_3 PF13758.6 GAP84344.1 - 2.8e-24 85.0 0.8 7.8e-24 83.6 0.8 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 GAP84344.1 - 4e-23 82.1 0.1 4e-23 82.1 0.1 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF3835) Mitoc_mL59 PF18126.1 GAP84344.1 - 0.0081 16.5 0.9 0.032 14.6 0.9 2.0 1 1 1 2 2 2 1 Mitochondrial ribosomal protein mL59 ABC_tran_CTD PF16326.5 GAP84344.1 - 0.04 14.2 0.2 0.04 14.2 0.2 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain HR1 PF02185.16 GAP84344.1 - 0.14 12.3 0.9 0.49 10.5 0.1 2.3 2 0 0 2 2 2 0 Hr1 repeat STAT_alpha PF01017.20 GAP84344.1 - 0.15 11.9 2.4 0.1 12.5 0.3 1.8 2 0 0 2 2 2 0 STAT protein, all-alpha domain Prefoldin_2 PF01920.20 GAP84344.1 - 7.2 6.6 8.5 1.3 9.0 0.1 3.4 3 1 0 3 3 3 0 Prefoldin subunit RhgB_N PF09284.10 GAP84345.1 - 4.1e-92 308.3 6.6 6.3e-92 307.6 6.6 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 GAP84345.1 - 2e-35 122.1 0.1 7.6e-35 120.2 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 GAP84345.1 - 5.9e-21 74.0 3.7 5.9e-21 74.0 3.7 3.6 4 1 1 5 5 5 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 GAP84345.1 - 0.00021 21.5 0.6 0.00021 21.5 0.6 2.8 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain PEGA PF08308.11 GAP84345.1 - 0.078 12.9 0.1 0.75 9.7 0.0 2.5 2 0 0 2 2 2 0 PEGA domain WLM PF08325.10 GAP84346.1 - 8.1e-63 212.0 0.0 8.1e-63 212.0 0.0 2.0 3 0 0 3 3 3 1 WLM domain zf-RanBP PF00641.18 GAP84346.1 - 0.002 17.4 5.3 0.002 17.4 5.3 3.3 2 1 1 3 3 3 2 Zn-finger in Ran binding protein and others RskA PF10099.9 GAP84346.1 - 0.0085 16.4 10.4 0.0085 16.4 10.4 1.9 2 1 0 2 2 2 1 Anti-sigma-K factor rskA DUF45 PF01863.17 GAP84346.1 - 0.14 12.1 1.3 0.4 10.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 PAT1 PF09770.9 GAP84346.1 - 0.22 9.7 7.4 0.33 9.2 7.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 GAP84346.1 - 0.23 11.1 8.2 0.51 9.9 8.2 1.5 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 GAP84346.1 - 0.35 10.8 8.1 0.52 10.3 8.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit C1_2 PF03107.16 GAP84346.1 - 0.68 10.3 5.6 4 7.8 0.2 2.6 2 0 0 2 2 2 0 C1 domain PHD PF00628.29 GAP84346.1 - 2.2 8.2 9.1 20 5.2 4.1 2.7 2 0 0 2 2 2 0 PHD-finger DZR PF12773.7 GAP84346.1 - 6 7.0 10.8 50 4.0 10.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon Glyco_hydro_71 PF03659.14 GAP84347.1 - 1.4e-84 284.1 0.1 1.7e-84 283.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 PPC PF04151.15 GAP84347.1 - 0.19 12.9 0.4 0.19 12.9 0.4 3.5 3 1 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain PQQ_2 PF13360.6 GAP84348.1 - 6.2e-06 26.0 1.7 0.00012 21.7 0.1 3.3 3 1 1 4 4 4 1 PQQ-like domain WD40 PF00400.32 GAP84348.1 - 8e-06 26.5 16.0 0.041 14.8 0.0 7.9 8 1 0 8 8 8 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP84348.1 - 0.00037 20.7 0.4 2.2 8.6 0.0 4.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAP84348.1 - 0.002 18.0 0.3 2.2 8.3 0.0 3.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 GAP84348.1 - 0.006 15.6 0.0 5.7 5.8 0.0 3.3 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 GAP84348.1 - 0.011 15.6 0.4 2.9 8.0 0.1 3.2 2 0 0 2 2 2 0 PQQ enzyme repeat Hira PF07569.11 GAP84348.1 - 0.17 11.6 0.1 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split PQQ_3 PF13570.6 GAP84348.1 - 1.3 9.6 4.3 19 5.9 0.1 4.5 5 0 0 5 5 5 0 PQQ-like domain Rad4 PF03835.15 GAP84349.1 - 7.1e-16 58.2 1.8 1.6e-15 57.1 1.8 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 GAP84349.1 - 6.8e-15 55.5 1.7 1.5e-14 54.4 1.7 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SAP130_C PF16014.5 GAP84349.1 - 0.74 8.8 5.5 0.21 10.6 0.2 2.1 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus Scramblase PF03803.15 GAP84352.1 - 0.022 14.1 0.3 5.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Scramblase zf-LITAF-like PF10601.9 GAP84353.1 - 0.00013 22.1 5.0 0.11 12.8 2.8 2.1 2 0 0 2 2 2 2 LITAF-like zinc ribbon domain Lar_restr_allev PF14354.6 GAP84353.1 - 0.028 14.8 1.4 0.084 13.3 1.4 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar SWIRM-assoc_2 PF16496.5 GAP84354.1 - 0.00045 19.2 1.3 0.00045 19.2 1.3 4.6 4 1 0 5 5 5 1 SWIRM-associated domain at the N-terminal ELH PF02323.15 GAP84354.1 - 0.21 10.9 12.6 0.81 9.0 12.6 2.0 1 0 0 1 1 1 0 Egg-laying hormone precursor MFS_1 PF07690.16 GAP84355.1 - 9.8e-46 156.3 55.5 3.8e-45 154.4 53.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP84355.1 - 2.1e-16 59.5 16.0 3.1e-16 59.0 16.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP84355.1 - 2.1e-15 56.5 3.7 2.1e-15 56.5 3.7 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter LETM1 PF07766.13 GAP84357.1 - 2.5e-103 345.1 0.7 2.5e-103 345.1 0.7 1.7 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 GAP84357.1 - 0.00093 18.9 0.0 0.047 13.5 0.0 3.2 3 0 0 3 3 3 1 SAP domain DUF1664 PF07889.12 GAP84358.1 - 0.01 15.9 2.1 0.02 14.9 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) GPS2_interact PF15784.5 GAP84358.1 - 0.018 15.5 0.3 0.063 13.7 0.3 1.9 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Nup54 PF13874.6 GAP84358.1 - 0.037 14.1 5.8 0.086 13.0 5.2 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Tropomyosin_1 PF12718.7 GAP84358.1 - 0.69 10.1 6.0 0.37 11.0 2.2 2.3 2 0 0 2 2 2 0 Tropomyosin like BLOC1_2 PF10046.9 GAP84358.1 - 1.2 9.5 8.2 6.8 7.1 6.1 2.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 GAP84358.1 - 5 7.6 10.4 0.67 10.5 5.7 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region CLTH PF10607.9 GAP84359.1 - 3.8e-32 111.2 0.0 6.5e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 GAP84359.1 - 6.1e-06 26.2 0.1 1.2e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAP84359.1 - 0.00075 19.8 0.1 0.0013 19.0 0.1 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 GAP84359.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 GAP84359.1 - 0.0051 16.7 0.1 0.0087 16.0 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAP84359.1 - 0.007 16.2 0.2 0.013 15.3 0.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAP84359.1 - 0.011 15.6 0.2 0.019 14.8 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP84359.1 - 0.055 13.3 0.4 0.11 12.4 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP84359.1 - 0.057 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAP84359.1 - 0.11 12.7 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MIG-14_Wnt-bd PF06664.12 GAP84360.1 - 0.0018 17.5 1.2 0.0018 17.5 1.2 3.0 1 1 1 2 2 2 1 Wnt-binding factor required for Wnt secretion Ctr PF04145.15 GAP84360.1 - 1.8 9.2 6.8 16 6.1 0.1 3.6 3 1 0 3 3 3 0 Ctr copper transporter family MpPF26 PF07666.11 GAP84360.1 - 7.3 6.7 17.0 0.14 12.3 6.1 3.0 2 2 0 2 2 2 0 M penetrans paralogue family 26 PPP4R2 PF09184.11 GAP84361.1 - 1.2e-08 34.9 0.0 1.2e-08 34.9 0.0 2.4 2 1 0 2 2 2 1 PPP4R2 PsiA PF06952.11 GAP84361.1 - 0.17 11.1 0.0 0.39 9.9 0.0 1.5 1 0 0 1 1 1 0 PsiA protein AAA_23 PF13476.6 GAP84362.1 - 1.2e-29 104.3 0.1 1.2e-29 104.3 0.1 7.2 1 1 3 5 5 5 1 AAA domain AAA_15 PF13175.6 GAP84362.1 - 1.3e-11 44.8 35.2 2.2e-09 37.5 0.0 5.0 1 1 2 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 GAP84362.1 - 3.4e-09 37.0 6.5 0.00066 19.6 1.4 3.7 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GAP84362.1 - 1.5e-06 28.3 0.0 6.3e-06 26.3 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 GAP84362.1 - 9.2e-06 25.3 0.0 9.2e-06 25.3 0.0 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAP84362.1 - 0.0067 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain BRE1 PF08647.11 GAP84362.1 - 0.011 15.8 1.1 0.011 15.8 1.1 12.1 6 5 4 12 12 12 0 BRE1 E3 ubiquitin ligase AAA_16 PF13191.6 GAP84362.1 - 0.027 14.9 0.0 0.027 14.9 0.0 4.6 3 2 0 3 3 3 0 AAA ATPase domain AAA_13 PF13166.6 GAP84362.1 - 0.06 12.0 0.0 0.06 12.0 0.0 6.9 2 1 4 7 7 7 0 AAA domain ABC_tran PF00005.27 GAP84362.1 - 0.12 12.9 0.0 0.12 12.9 0.0 7.7 4 2 0 4 4 4 0 ABC transporter GATA PF00320.27 GAP84363.1 - 1.4e-15 56.6 5.5 2.5e-15 55.8 5.5 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 GAP84363.1 - 2.4e-13 50.2 0.0 4.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 GAP84363.1 - 4e-06 27.0 0.0 1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 GAP84363.1 - 1.8e-05 24.7 0.1 5.2e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 GAP84363.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 GAP84363.1 - 0.0081 16.3 0.2 0.018 15.1 0.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain PAS_9 PF13426.7 GAP84363.1 - 0.024 14.9 0.3 0.061 13.6 0.0 1.9 2 0 0 2 2 2 0 PAS domain TF_Zn_Ribbon PF08271.12 GAP84363.1 - 0.15 11.6 0.6 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.6 GAP84363.1 - 1.6 8.7 5.3 0.37 10.7 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) ECH_1 PF00378.20 GAP84364.1 - 3.7e-40 137.8 0.0 1.9e-26 92.9 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAP84364.1 - 4.7e-22 78.9 0.1 6.9e-19 68.5 0.2 2.5 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase FAD_binding_3 PF01494.19 GAP84366.1 - 3.9e-70 236.8 0.0 4.7e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP84366.1 - 1.4e-06 28.2 0.1 2.6e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAP84366.1 - 1.1e-05 24.8 0.0 2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 GAP84366.1 - 4.7e-05 23.5 0.1 0.00014 22.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAP84366.1 - 0.0001 21.5 0.2 0.0019 17.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP84366.1 - 0.00024 20.5 1.0 0.0025 17.1 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP84366.1 - 0.00064 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP84366.1 - 0.0013 17.5 0.2 0.0058 15.4 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 GAP84366.1 - 0.0024 18.4 0.9 0.06 13.9 0.5 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAP84366.1 - 0.003 16.5 0.0 0.0056 15.6 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Phe_hydrox_dim PF07976.12 GAP84366.1 - 0.0031 17.6 0.0 0.01 15.9 0.0 1.9 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain TrkA_N PF02254.18 GAP84366.1 - 0.0054 17.0 0.1 0.031 14.5 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 GAP84366.1 - 0.021 15.2 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 GAP84366.1 - 0.031 13.9 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 GAP84366.1 - 0.13 11.3 0.2 0.2 10.7 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Transp_cyt_pur PF02133.15 GAP84367.1 - 1e-37 130.0 29.4 1e-37 130.0 29.4 1.8 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin F-box PF00646.33 GAP84368.1 - 0.0061 16.4 1.2 0.035 14.0 0.3 2.4 2 0 0 2 2 2 1 F-box domain RecR PF02132.15 GAP84368.1 - 2.3 7.8 7.4 1.6 8.4 0.1 2.6 2 1 0 2 2 2 0 RecR protein ADH_N PF08240.12 GAP84370.1 - 4.3e-25 87.7 0.5 6.8e-25 87.1 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP84370.1 - 0.00016 21.7 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP84370.1 - 0.059 14.4 0.0 0.088 13.9 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 GAP84370.1 - 0.12 12.3 0.2 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase DUF2401 PF10287.9 GAP84371.1 - 4.5e-81 271.8 0.0 6.4e-81 271.3 0.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 GAP84371.1 - 4.2e-23 81.5 0.0 1.1e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SelP_N PF04592.14 GAP84371.1 - 0.14 11.5 1.4 8.5 5.7 3.0 2.3 3 0 0 3 3 3 0 Selenoprotein P, N terminal region DUF423 PF04241.15 GAP84372.1 - 1.6e-23 82.7 3.4 2.2e-23 82.2 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Lyase_1 PF00206.20 GAP84373.1 - 2.9e-87 293.0 0.0 3.9e-87 292.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 GAP84373.1 - 6.3e-23 81.3 0.1 1.5e-22 80.1 0.1 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SHOCT PF09851.9 GAP84373.1 - 0.083 12.7 0.4 0.81 9.5 0.1 2.5 2 0 0 2 2 2 0 Short C-terminal domain Pribosyltran PF00156.27 GAP84374.1 - 4e-13 49.2 0.0 8.8e-13 48.1 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain PRTase_3 PF15610.6 GAP84374.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like UPRTase PF14681.6 GAP84374.1 - 0.14 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Cytochrom_B558a PF05038.13 GAP84375.1 - 0.0081 15.8 0.3 0.026 14.1 0.1 1.9 1 1 1 2 2 2 1 Cytochrome Cytochrome b558 alpha-subunit Zn_clus PF00172.18 GAP84376.1 - 1e-10 41.5 9.3 2.8e-10 40.2 9.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP84376.1 - 5.2e-07 29.0 0.1 8e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pex2_Pex12 PF04757.14 GAP84377.1 - 6.5e-36 124.0 1.9 9.3e-36 123.5 1.9 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 GAP84377.1 - 0.00017 21.6 4.2 0.00033 20.8 4.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 GAP84377.1 - 0.021 14.9 1.0 0.055 13.5 1.0 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 GAP84377.1 - 0.11 12.3 2.1 0.27 11.1 2.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP84377.1 - 0.33 10.8 4.4 0.12 12.3 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBN_N PF03810.19 GAP84378.1 - 1.9e-12 46.9 0.3 2.4e-11 43.4 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GAP84378.1 - 2.3e-05 24.5 3.0 0.00048 20.2 0.0 3.7 3 1 0 4 4 4 1 Exportin 1-like protein Cse1 PF08506.10 GAP84378.1 - 0.039 12.8 0.0 0.094 11.5 0.0 1.6 2 0 0 2 2 2 0 Cse1 PH_6 PF15406.6 GAP84379.1 - 2.2e-43 147.1 1.3 2.2e-43 147.1 1.3 3.1 4 0 0 4 4 4 1 Pleckstrin homology domain PH PF00169.29 GAP84379.1 - 0.011 16.3 0.6 0.024 15.1 0.0 2.0 2 0 0 2 2 2 0 PH domain tRNA-synt_2 PF00152.20 GAP84381.1 - 2.6e-67 227.1 0.0 3.2e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAP84381.1 - 1e-10 41.4 0.0 2.5e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAP84381.1 - 1.4e-05 24.8 0.0 0.0045 16.5 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.15 GAP84382.1 - 3.7e-19 68.1 1.4 4.3e-19 67.9 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger BrkDBD PF09607.10 GAP84382.1 - 0.078 12.8 0.1 0.45 10.3 0.0 2.1 2 1 0 2 2 2 0 Brinker DNA-binding domain ADK PF00406.22 GAP84383.1 - 2.1e-38 131.8 0.0 5.2e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 GAP84383.1 - 1.1e-14 54.0 0.0 2.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 GAP84383.1 - 1.4e-14 54.7 0.1 5.8e-10 39.7 0.0 2.5 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 GAP84383.1 - 8e-06 26.4 0.0 0.037 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAP84383.1 - 0.012 15.7 0.8 0.039 14.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 GAP84383.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP84383.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_hydro_76 PF03663.14 GAP84384.1 - 6.5e-19 68.7 2.1 4.9e-12 46.0 0.0 3.2 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 ER_lumen_recept PF00810.18 GAP84386.1 - 2.4e-39 135.5 10.2 2.4e-39 135.5 10.2 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 GAP84386.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.8 3 0 0 3 3 3 0 PQ loop repeat Cwf_Cwc_15 PF04889.12 GAP84386.1 - 0.36 10.5 11.7 0.52 10.0 11.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tub_N PF16322.5 GAP84386.1 - 3.1 8.2 6.2 5 7.5 6.2 1.3 1 0 0 1 1 1 0 Tubby N-terminal zf-GRF PF06839.12 GAP84387.1 - 0.051 13.7 1.8 0.086 12.9 1.8 1.5 1 1 0 1 1 1 0 GRF zinc finger Ribosomal_L37ae PF01780.19 GAP84388.1 - 2.8e-38 129.9 5.6 3.1e-38 129.7 5.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 GAP84388.1 - 0.046 13.7 6.7 0.075 13.0 6.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 GAP84388.1 - 0.091 12.8 2.6 5.3 7.1 2.6 2.2 1 1 0 1 1 1 0 BED zinc finger A2L_zn_ribbon PF08792.10 GAP84388.1 - 0.16 11.7 1.9 4.5 7.1 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain CHCH PF06747.13 GAP84391.1 - 0.019 15.1 2.8 0.14 12.4 0.3 2.4 2 0 0 2 2 2 0 CHCH domain Mitochondr_Som1 PF11093.8 GAP84391.1 - 0.098 12.7 0.2 0.26 11.3 0.2 1.8 1 0 0 1 1 1 0 Mitochondrial export protein Som1 Ribosomal_S17_N PF16205.5 GAP84392.1 - 2.7e-33 114.1 1.1 5e-33 113.3 1.1 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 GAP84392.1 - 6e-26 90.4 2.2 7.2e-26 90.1 0.7 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 Spc7_N PF15402.6 GAP84393.1 - 6e-210 699.9 59.8 3.2e-208 694.2 59.8 2.2 1 1 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 GAP84393.1 - 2.3e-125 417.6 7.2 2.3e-125 417.6 7.2 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 GAP84393.1 - 9.1e-22 76.9 0.1 1.7e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Spc7_C2 PMEI PF04043.15 GAP84393.1 - 0.047 14.0 0.8 0.15 12.4 0.8 1.8 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Meis_PKNOX_N PF16493.5 GAP84393.1 - 0.19 12.1 0.6 0.62 10.4 0.6 1.8 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 Peptidase_C50 PF03568.17 GAP84393.1 - 0.22 10.6 3.1 0.42 9.7 3.1 1.4 1 0 0 1 1 1 0 Peptidase family C50 Pox_A_type_inc PF04508.12 GAP84393.1 - 0.38 10.7 8.3 6 6.9 0.2 4.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FapA PF03961.13 GAP84393.1 - 1.6 7.3 4.9 0.66 8.5 0.5 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4407 PF14362.6 GAP84393.1 - 2.9 7.2 12.5 0.11 11.8 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 GAP84393.1 - 5.3 7.5 12.9 0.21 12.0 3.1 2.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.22 GAP84393.1 - 7.3 6.9 10.2 0.34 11.2 3.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3275 PF11679.8 GAP84394.1 - 0.62 10.0 2.0 1.4 8.8 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Atg14 PF10186.9 GAP84395.1 - 1.5e-73 247.7 0.0 1.9e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 AIP3 PF03915.13 GAP84395.1 - 0.033 13.3 0.5 0.047 12.8 0.5 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 FAM76 PF16046.5 GAP84395.1 - 0.28 10.5 1.9 0.37 10.1 1.9 1.2 1 0 0 1 1 1 0 FAM76 protein Filament PF00038.21 GAP84395.1 - 1.9 8.0 8.6 0.45 10.1 5.6 1.4 2 0 0 2 2 2 0 Intermediate filament protein DUF488 PF04343.13 GAP84396.1 - 0.23 12.1 6.5 0.69 10.5 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF488 DUF3807 PF12720.7 GAP84397.1 - 7.5e-45 153.4 2.9 8.9e-45 153.2 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) NINJA_B PF16136.5 GAP84397.1 - 8.8 6.8 0.0 8.8 6.8 0.0 2.5 2 1 0 2 2 2 0 Putative nuclear localisation signal Pkinase PF00069.25 GAP84398.1 - 2.3e-66 223.9 0.1 2.7e-66 223.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84398.1 - 2.3e-20 73.0 0.0 3.2e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP84398.1 - 3.1e-08 33.8 0.0 5.5e-06 26.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAP84398.1 - 0.007 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAP84398.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 GAP84398.1 - 0.023 14.0 0.2 0.053 12.9 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GAP84398.1 - 0.093 12.3 0.1 0.093 12.3 0.1 2.2 4 0 0 4 4 4 0 Choline/ethanolamine kinase Scm3 PF10384.9 GAP84399.1 - 3.8e-14 52.2 0.5 3.8e-14 52.2 0.5 2.1 2 0 0 2 2 2 1 Centromere protein Scm3 AT_hook PF02178.19 GAP84399.1 - 0.032 14.1 2.6 0.17 11.9 2.6 2.4 1 0 0 1 1 1 0 AT hook motif FISNA PF14484.6 GAP84399.1 - 0.14 12.4 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 Fish-specific NACHT associated domain APG6 PF04111.12 GAP84400.1 - 4.4e-64 215.7 0.0 6.5e-64 215.2 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 GAP84400.1 - 3.1e-38 131.3 14.4 4.4e-38 130.8 14.4 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region zf-C4H2 PF10146.9 GAP84400.1 - 0.002 18.5 0.1 0.0035 17.7 0.1 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein KASH_CCD PF14662.6 GAP84400.1 - 0.015 15.1 10.8 0.024 14.5 10.8 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ERM PF00769.19 GAP84400.1 - 0.045 13.6 11.5 0.077 12.8 11.5 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 GAP84400.1 - 0.25 10.6 8.8 1.9 7.7 9.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 GAP84400.1 - 0.28 11.3 10.5 0.46 10.6 10.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 GAP84400.1 - 0.84 7.5 4.8 1.2 7.0 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 GAP84400.1 - 2.1 8.5 8.7 4.6 7.4 8.7 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF724 PF05266.14 GAP84400.1 - 2.3 8.0 11.0 1.4 8.7 6.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HET PF06985.11 GAP84401.1 - 2e-20 73.6 0.0 4.4e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 GAP84401.1 - 0.0014 19.0 0.0 0.0045 17.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) C166 PF17615.2 GAP84402.1 - 5.1e-26 91.7 16.5 3.6e-25 89.0 16.5 2.0 1 1 0 1 1 1 1 Family of unknown function HsbA PF12296.8 GAP84402.1 - 0.036 14.5 2.0 0.43 11.0 0.4 2.6 2 1 0 2 2 2 0 Hydrophobic surface binding protein A COesterase PF00135.28 GAP84403.1 - 2e-51 175.4 0.0 2.9e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 GAP84404.1 - 7.2e-18 66.0 0.3 9.6e-18 65.6 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAP84404.1 - 0.00033 20.6 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP84404.1 - 0.0015 17.8 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAP84404.1 - 0.017 15.3 0.0 0.052 13.7 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain LIDHydrolase PF10230.9 GAP84404.1 - 0.021 14.4 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 GAP84404.1 - 0.051 13.3 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S8 PF00082.22 GAP84405.1 - 5.9e-30 104.6 14.0 7.6e-30 104.2 14.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAP84405.1 - 2.4e-18 66.6 0.2 4.2e-18 65.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3176 PF11374.8 GAP84406.1 - 3.1e-31 107.8 3.3 6.7e-31 106.7 3.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Glyco_hydro_18 PF00704.28 GAP84408.1 - 3.1e-67 227.5 0.0 3.8e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ANAPC4_WD40 PF12894.7 GAP84409.1 - 0.00072 19.8 0.0 0.1 12.9 0.0 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP84409.1 - 0.0047 15.6 0.0 0.0074 15.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 SDA1 PF05285.12 GAP84409.1 - 0.031 13.7 17.9 0.042 13.3 17.9 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 GAP84409.1 - 0.074 13.2 8.9 0.11 12.7 8.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 GAP84409.1 - 0.15 11.4 12.8 0.2 10.9 12.8 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAP84409.1 - 0.22 9.8 17.6 0.31 9.3 17.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 GAP84409.1 - 0.58 8.5 14.0 0.8 8.1 14.0 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 GAP84409.1 - 0.95 7.6 14.2 1.2 7.2 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.32 GAP84409.1 - 5.2 8.1 11.6 10 7.2 0.0 5.1 7 0 0 7 7 7 0 WD domain, G-beta repeat RNA_polI_A34 PF08208.11 GAP84409.1 - 7.8 6.5 15.0 13 5.8 15.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Inositol_P PF00459.25 GAP84410.1 - 2e-79 266.9 0.0 2.5e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family SDH_C PF18317.1 GAP84411.1 - 4.5e-05 23.1 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_dh_N PF08501.11 GAP84412.1 - 3.1e-20 72.2 0.0 5.9e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 GAP84412.1 - 0.045 13.8 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 GAP84413.1 - 1e-123 413.6 19.1 1.8e-123 412.7 19.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP84413.1 - 2.2e-22 79.5 38.1 5.1e-22 78.3 35.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AP_endonuc_2 PF01261.24 GAP84414.1 - 3e-32 111.8 0.5 4.7e-32 111.1 0.5 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Carot_N PF09150.10 GAP84414.1 - 0.091 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal Fungal_trans PF04082.18 GAP84415.1 - 3.5e-18 65.6 0.1 6.1e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP84415.1 - 0.00016 21.7 11.9 0.0003 20.9 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.15 GAP84416.1 - 8.6e-22 78.5 0.0 1.5e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 GAP84416.1 - 1.8e-21 76.1 0.0 4.3e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 GAP84416.1 - 5.7e-11 42.8 0.0 1.3e-10 41.6 0.0 1.6 2 0 0 2 2 2 1 Shikimate kinase SDH_C PF18317.1 GAP84416.1 - 3e-09 36.5 0.4 6.7e-09 35.4 0.4 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 GAP84416.1 - 3.2e-06 27.3 0.1 6.7e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 GAP84416.1 - 0.004 17.3 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sacchrp_dh_NADP PF03435.18 GAP84416.1 - 0.16 12.3 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Zeta_toxin PF06414.12 GAP84416.1 - 0.32 10.2 1.3 0.39 10.0 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin CTD PF12815.7 GAP84417.1 - 8e-25 87.2 61.2 1.5e-16 60.7 18.3 4.8 1 1 3 4 4 4 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.13 GAP84417.1 - 2.5e-22 78.6 0.0 4.2e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 GAP84417.1 - 5e-17 62.7 9.2 5e-17 62.7 9.2 3.4 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 GAP84417.1 - 9.3e-05 22.2 16.8 0.0024 17.7 0.2 5.9 6 0 0 6 6 6 2 KOW motif DUF3912 PF13051.6 GAP84417.1 - 0.12 12.6 0.3 3.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) WD40 PF00400.32 GAP84418.1 - 1.1e-11 45.1 13.0 2.7e-05 24.8 0.0 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat CTP_transf_like PF01467.26 GAP84419.1 - 1.4e-05 25.3 0.0 2.9e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like adh_short_C2 PF13561.6 GAP84420.1 - 5.5e-46 157.0 0.0 6.5e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP84420.1 - 5.5e-37 127.1 0.1 7.5e-37 126.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP84420.1 - 3.9e-12 46.5 0.0 5.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP84420.1 - 3.4e-06 26.7 0.1 5e-06 26.2 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP84420.1 - 1.2e-05 24.9 0.0 1.6e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAP84420.1 - 0.00038 19.5 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAP84420.1 - 0.0086 15.2 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 GAP84420.1 - 0.12 12.4 0.2 0.93 9.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PAN_4 PF14295.6 GAP84421.1 - 0.015 15.2 1.8 0.035 14.0 1.8 1.6 1 0 0 1 1 1 0 PAN domain Spc7 PF08317.11 GAP84422.1 - 0.0098 14.8 4.9 0.19 10.6 0.6 2.4 2 0 0 2 2 2 2 Spc7 kinetochore protein TRAF_BIRC3_bd PF16673.5 GAP84422.1 - 0.093 12.5 0.2 0.093 12.5 0.2 2.8 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Bacillus_HBL PF05791.11 GAP84422.1 - 0.99 9.2 4.3 14 5.5 0.3 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) GTP-bdg_M PF16360.5 GAP84422.1 - 1.2 9.8 4.5 1.8 9.2 0.9 3.0 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Seryl_tRNA_N PF02403.22 GAP84422.1 - 1.2 9.4 9.6 0.38 11.0 5.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.14 GAP84422.1 - 1.4 8.7 8.5 0.18 11.7 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fmp27_WPPW PF10359.9 GAP84422.1 - 3.3 6.4 7.5 1.1 8.0 2.4 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF1748 PF08520.10 GAP84423.1 - 2.5e-32 110.6 0.1 3e-32 110.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 GAP84424.1 - 4.3e-169 561.9 3.0 5.5e-169 561.6 3.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 GAP84424.1 - 6.9e-35 119.8 0.0 2e-34 118.3 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 GAP84424.1 - 0.00022 20.4 0.6 0.00064 18.9 0.3 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Ank PF00023.30 GAP84425.1 - 5.4e-16 58.2 1.7 0.015 15.7 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 GAP84425.1 - 3.3e-12 45.4 4.6 0.0061 17.0 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 GAP84425.1 - 4.2e-12 46.3 0.4 0.072 13.7 0.0 6.2 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP84425.1 - 1.6e-11 44.6 0.0 3.5e-05 24.3 0.0 4.1 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP84425.1 - 2.5e-08 34.0 0.0 0.012 15.9 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) F-box-like PF12937.7 GAP84425.1 - 4e-08 33.0 0.2 2e-07 30.8 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAP84425.1 - 5.8e-07 29.2 0.4 1.8e-06 27.6 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 GAP84425.1 - 0.16 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 F-box LCM PF04072.14 GAP84426.1 - 1.4e-20 74.1 0.0 2.2e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TM1586_NiRdase PF14512.6 GAP84426.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative TM nitroreductase MFS_1 PF07690.16 GAP84427.1 - 2.7e-48 164.7 29.4 2.7e-48 164.7 29.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP84427.1 - 4.9e-13 48.7 14.0 4.9e-13 48.7 14.0 2.7 2 2 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 GAP84427.1 - 5e-06 26.0 3.2 5e-06 26.0 3.2 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 GAP84427.1 - 7.5e-06 24.6 0.3 7.5e-06 24.6 0.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Vut_1 PF02592.15 GAP84427.1 - 0.87 9.9 15.5 1.3 9.4 0.2 3.9 3 1 1 4 4 4 0 Putative vitamin uptake transporter OATP PF03137.20 GAP84427.1 - 5.3 5.2 9.0 7.7 4.7 5.7 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 GAP84428.1 - 5.4e-17 61.7 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP84428.1 - 4.4e-05 23.5 10.1 7.9e-05 22.7 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 GAP84429.1 - 7.5e-39 133.7 0.0 9.7e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 GAP84430.1 - 1.3e-31 109.8 31.7 1.3e-31 109.8 31.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily HPP PF04982.13 GAP84430.1 - 4.2 7.6 13.5 0.03 14.5 3.1 2.8 3 0 0 3 3 3 0 HPP family MMPL PF03176.15 GAP84430.1 - 5.3 5.9 10.5 0.029 13.3 0.7 2.2 3 0 0 3 3 3 0 MMPL family Polysacc_synt_4 PF04669.13 GAP84431.1 - 3.1e-22 79.1 0.9 1.2e-20 73.8 0.9 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_membrane PF00664.23 GAP84432.1 - 7.9e-79 265.1 28.6 6e-48 163.9 12.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAP84432.1 - 1e-61 207.4 0.0 2.1e-31 109.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAP84432.1 - 6.4e-14 51.9 0.8 2.4e-05 23.9 0.0 5.2 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAP84432.1 - 6.9e-11 42.5 0.6 0.07 12.9 0.0 4.7 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAP84432.1 - 6.3e-08 32.3 0.5 0.018 14.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 GAP84432.1 - 3.5e-06 26.1 0.0 0.00016 20.7 0.0 2.9 3 0 0 3 3 3 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 GAP84432.1 - 4.2e-06 26.8 0.0 0.083 12.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAP84432.1 - 5.7e-06 26.8 1.7 0.23 11.8 0.1 4.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 GAP84432.1 - 6.9e-06 26.7 0.3 0.016 15.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAP84432.1 - 5.5e-05 23.5 2.6 0.69 10.2 0.1 4.0 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 GAP84432.1 - 0.00023 20.8 0.0 0.58 9.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 GAP84432.1 - 0.00035 21.0 0.0 0.14 12.6 0.0 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 GAP84432.1 - 0.0011 19.5 0.0 3 8.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 GAP84432.1 - 0.0028 17.4 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 GAP84432.1 - 0.0029 17.7 0.1 1.5 8.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.14 GAP84432.1 - 0.0037 17.3 0.4 5.3 7.1 0.0 4.0 5 1 0 5 5 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAP84432.1 - 0.0061 16.7 0.0 6.9 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAP84432.1 - 0.0084 15.8 0.1 7.8 6.2 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.22 GAP84432.1 - 0.012 16.0 0.0 5.3 7.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 GAP84432.1 - 0.03 14.0 0.2 4.7 6.9 0.0 3.5 4 0 0 4 4 4 0 AAA domain NB-ARC PF00931.22 GAP84432.1 - 0.033 13.4 0.1 2.8 7.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 GAP84432.1 - 0.055 13.5 1.4 7.3 6.6 0.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 GAP84432.1 - 0.11 11.8 0.0 8.2 5.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DUF3987 PF13148.6 GAP84432.1 - 0.11 11.5 0.0 4.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_24 PF13479.6 GAP84432.1 - 0.12 12.1 0.3 6.4 6.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 GAP84432.1 - 0.15 12.4 0.6 7.1 7.0 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 GAP84432.1 - 1 8.6 2.5 41 3.4 0.1 3.1 3 0 0 3 3 3 0 KaiC Glyco_hydro_61 PF03443.14 GAP84433.1 - 3.2e-47 161.2 0.0 3.6e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NmrA PF05368.13 GAP84435.1 - 5.8e-24 84.9 0.0 7.6e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP84435.1 - 6.5e-19 68.5 1.0 1.1e-18 67.8 0.9 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP84435.1 - 0.0028 17.2 0.5 0.0067 15.9 0.5 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAP84435.1 - 0.0046 16.4 1.0 0.0079 15.7 1.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 GAP84435.1 - 0.011 14.8 0.3 0.016 14.3 0.3 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 GAP84435.1 - 0.037 13.0 0.3 0.13 11.2 0.3 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 GAP84435.1 - 0.053 13.4 1.3 0.12 12.2 1.3 1.7 1 1 0 1 1 1 0 KR domain DapB_N PF01113.20 GAP84435.1 - 0.071 13.2 0.4 0.13 12.4 0.4 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 GAP84435.1 - 0.078 13.4 0.5 0.13 12.7 0.5 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DFP PF04127.15 GAP84435.1 - 1 9.1 4.1 1.9 8.3 4.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Tyrosinase PF00264.20 GAP84436.1 - 1e-31 110.9 4.1 1.9e-31 110.1 4.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase UDPG_MGDP_dh PF00984.19 GAP84437.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain MutS_V PF00488.21 GAP84438.1 - 2.4e-66 223.4 0.2 4.5e-66 222.5 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAP84438.1 - 6.2e-43 147.3 1.5 1e-42 146.6 0.2 2.1 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 GAP84438.1 - 8e-31 106.6 0.0 1.8e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 GAP84438.1 - 1.3e-16 61.1 0.0 3.8e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 GAP84438.1 - 3.8e-12 46.4 0.4 9.7e-12 45.1 0.4 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 GAP84438.1 - 0.011 16.3 0.1 0.011 16.3 0.1 3.0 4 0 0 4 4 4 0 AAA domain AAA_21 PF13304.6 GAP84438.1 - 0.036 13.9 0.2 0.11 12.3 0.2 1.9 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAP84438.1 - 0.045 13.5 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3461 PF11944.8 GAP84438.1 - 0.14 12.3 1.2 0.39 10.8 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Hamartin PF04388.12 GAP84438.1 - 7.6 5.1 25.0 11 4.6 25.0 1.2 1 0 0 1 1 1 0 Hamartin protein UbiA PF01040.18 GAP84439.1 - 6.5e-56 189.4 19.3 6.5e-56 189.4 19.3 1.4 1 1 1 2 2 2 1 UbiA prenyltransferase family Mito_carr PF00153.27 GAP84439.1 - 0.028 14.3 0.5 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial carrier protein Myb_DNA-binding PF00249.31 GAP84440.1 - 1.6e-06 28.2 0.2 8.7e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP84440.1 - 0.00071 19.8 0.5 0.0025 18.0 0.3 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.8 GAP84440.1 - 0.073 13.2 0.0 0.23 11.6 0.0 2.0 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SUIM_assoc PF16619.5 GAP84440.1 - 1.8 8.6 13.2 0.17 12.0 3.5 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Sugar_tr PF00083.24 GAP84441.1 - 1.7e-116 389.8 22.1 2.3e-116 389.4 22.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP84441.1 - 1.9e-26 92.8 53.2 7.9e-24 84.2 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily mRNA_triPase PF02940.15 GAP84443.1 - 4.8e-49 167.0 0.0 4.8e-49 167.0 0.0 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain DUF4407 PF14362.6 GAP84443.1 - 0.31 10.3 10.9 0.54 9.6 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SpoIIP PF07454.11 GAP84443.1 - 0.37 10.2 11.7 0.71 9.3 11.7 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAA_23 PF13476.6 GAP84443.1 - 0.8 10.2 13.8 1.4 9.4 13.8 1.3 1 0 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.12 GAP84443.1 - 4.9 6.0 19.2 9.5 5.1 19.2 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARP1 PF12569.8 GAP84443.1 - 5.2 5.9 11.6 8.6 5.1 11.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RPN2_C PF18004.1 GAP84444.1 - 1.7e-49 167.8 1.8 4.7e-49 166.4 1.8 1.8 1 1 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 GAP84444.1 - 8.5e-35 117.4 25.3 4.4e-09 36.3 0.0 8.1 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 GAP84444.1 - 3.6e-20 72.1 0.1 1.7e-14 54.0 0.0 4.8 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 GAP84444.1 - 2.9e-06 27.0 0.2 0.22 11.9 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 GAP84444.1 - 3.5e-06 27.4 0.1 0.00088 19.7 0.0 4.4 1 1 3 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 GAP84444.1 - 0.0011 19.1 0.0 0.53 10.3 0.0 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Codanin-1_C PF15296.6 GAP84444.1 - 0.0032 17.5 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 Codanin-1 C-terminus PepSY_2 PF13670.6 GAP84444.1 - 2 8.5 5.8 4.1 7.5 0.6 3.5 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Xan_ur_permease PF00860.20 GAP84445.1 - 3.1e-62 210.5 34.9 6e-61 206.3 34.9 2.1 1 1 0 1 1 1 1 Permease family SOP4 PF17081.5 GAP84445.1 - 0.21 11.1 0.0 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein DUF3752 PF12572.8 GAP84446.1 - 0.051 14.1 9.3 0.062 13.8 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF3682 PF12446.8 GAP84446.1 - 0.59 10.6 7.4 0.67 10.4 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF3464 PF11947.8 GAP84446.1 - 0.7 9.6 7.1 0.8 9.4 7.1 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Connexin PF00029.19 GAP84446.1 - 0.71 9.6 4.6 0.68 9.7 4.6 1.0 1 0 0 1 1 1 0 Connexin NARP1 PF12569.8 GAP84446.1 - 0.84 8.5 13.4 0.91 8.4 13.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 LMBR1 PF04791.16 GAP84446.1 - 0.95 8.3 2.2 1 8.2 2.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_S2 PF00318.20 GAP84446.1 - 1 8.6 4.1 1.1 8.4 4.1 1.0 1 0 0 1 1 1 0 Ribosomal protein S2 Borrelia_P83 PF05262.11 GAP84446.1 - 2.2 6.7 12.3 2.4 6.5 12.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 GAP84446.1 - 2.6 6.7 5.3 2.7 6.6 5.3 1.0 1 0 0 1 1 1 0 Presenilin DUF3391 PF11871.8 GAP84446.1 - 3.3 8.2 11.0 4 8.0 11.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF2992 PF11208.8 GAP84446.1 - 3.6 7.8 15.7 4.3 7.6 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) RR_TM4-6 PF06459.12 GAP84446.1 - 4.7 7.0 10.5 5.2 6.8 10.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tho2 PF11262.8 GAP84446.1 - 4.8 6.3 7.8 5 6.2 7.8 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4337 PF14235.6 GAP84446.1 - 4.8 7.3 9.7 5.3 7.1 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Peptidase_S49_N PF08496.10 GAP84446.1 - 5 7.2 10.7 6.7 6.8 10.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TMPIT PF07851.13 GAP84446.1 - 5.7 6.1 5.1 6.1 6.0 5.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein Casc1_N PF15927.5 GAP84446.1 - 8.9 5.9 16.3 11 5.7 16.3 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ribosomal_S19 PF00203.21 GAP84447.1 - 5.1e-30 103.2 0.0 6.9e-30 102.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Pedibin PF08182.11 GAP84448.1 - 0.0081 15.9 0.5 0.022 14.5 0.5 1.8 1 0 0 1 1 1 1 Pedibin/Hym-346 family TMF_DNA_bd PF12329.8 GAP84448.1 - 0.012 15.6 5.1 0.019 15.0 5.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Glyco_hydro_61 PF03443.14 GAP84449.1 - 1.3e-55 188.6 0.0 2.4e-55 187.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DprA_WH PF17782.1 GAP84449.1 - 3.5 7.8 5.2 13 6.0 1.9 2.8 2 0 0 2 2 2 0 DprA winged helix domain Glyco_hydro_31 PF01055.26 GAP84450.1 - 3.3e-149 497.8 5.7 4.2e-149 497.5 5.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAP84450.1 - 2.5e-30 105.0 0.0 4e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase DUF5110 PF17137.4 GAP84450.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) zf-CCCH PF00642.24 GAP84451.1 - 5.2e-13 48.6 16.6 1.7e-06 27.8 0.3 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAP84451.1 - 9.8e-11 41.3 17.2 2.3e-06 27.5 2.5 3.4 3 0 0 3 3 3 3 Zinc finger domain Torus PF16131.5 GAP84451.1 - 6.7e-07 30.0 11.2 0.035 14.8 0.3 3.1 1 1 2 3 3 3 3 Torus domain zf-CCCH_4 PF18044.1 GAP84451.1 - 0.0027 17.5 19.5 0.46 10.3 3.0 3.5 3 0 0 3 3 3 3 CCCH-type zinc finger GRP PF07172.11 GAP84451.1 - 6.2 7.6 25.2 9.5 7.0 25.2 1.4 1 0 0 1 1 1 0 Glycine rich protein family zf-CCCH_3 PF15663.5 GAP84451.1 - 8.9 6.6 6.7 6.5 7.0 4.1 1.8 1 1 1 2 2 2 0 Zinc-finger containing family DUF1776 PF08643.10 GAP84452.1 - 1.5e-100 336.4 0.0 1.8e-100 336.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Oxidored_FMN PF00724.20 GAP84453.1 - 9.4e-93 311.2 0.0 1.1e-92 311.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Toxin_27 PF08099.11 GAP84453.1 - 0.069 13.3 0.9 0.12 12.5 0.9 1.4 1 0 0 1 1 1 0 Scorpion calcine family Kinesin PF00225.23 GAP84454.1 - 1e-47 162.7 0.0 2.8e-24 85.7 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 GAP84454.1 - 0.00024 21.1 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding DUF4140 PF13600.6 GAP84454.1 - 0.99 9.9 3.9 1.1 9.8 1.1 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) p450 PF00067.22 GAP84455.1 - 1.1e-62 212.3 0.0 2.1e-62 211.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAP84456.1 - 1.3e-32 113.1 26.3 1.8e-32 112.7 26.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Neurensin PF14927.6 GAP84456.1 - 0.05 13.3 0.3 14 5.3 0.0 2.7 3 0 0 3 3 3 0 Neurensin BATS PF06968.13 GAP84457.1 - 2.8e-23 81.8 0.0 6.8e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 GAP84457.1 - 4.3e-15 56.5 0.1 8.8e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_1_2 PF00155.21 GAP84458.1 - 6.3e-20 71.7 0.0 9.1e-20 71.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_helix PF13229.6 GAP84458.1 - 0.11 12.4 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 Right handed beta helix region Aminotran_3 PF00202.21 GAP84459.1 - 1.1e-41 142.9 0.0 6.4e-23 81.1 0.0 3.2 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 GAP84459.1 - 5e-05 23.2 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Peptidase_M35 PF02102.15 GAP84460.1 - 9.5e-81 271.4 22.4 1.2e-80 271.2 22.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 GAP84460.1 - 1.3e-39 136.1 7.1 1.3e-39 136.1 7.1 2.1 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase Apolipoprotein PF01442.18 GAP84461.1 - 0.0025 17.7 1.3 0.0032 17.4 1.3 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Leu_zip PF15294.6 GAP84461.1 - 0.0089 15.6 0.2 0.0099 15.4 0.2 1.1 1 0 0 1 1 1 1 Leucine zipper CdvA PF18822.1 GAP84461.1 - 0.0091 15.8 0.6 0.015 15.1 0.6 1.4 1 0 0 1 1 1 1 CdvA-like coiled-coil domain Sds3 PF08598.11 GAP84461.1 - 0.024 14.6 0.3 0.034 14.1 0.3 1.1 1 0 0 1 1 1 0 Sds3-like HSCB_C PF07743.13 GAP84461.1 - 0.027 14.9 3.6 0.13 12.8 2.9 2.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Syntaxin-6_N PF09177.11 GAP84461.1 - 0.051 14.1 0.5 0.15 12.7 0.5 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 GAP84461.1 - 0.06 13.4 0.4 0.14 12.2 0.2 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFP_35_N PF07334.13 GAP84461.1 - 0.067 13.3 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Prominin PF05478.11 GAP84461.1 - 0.073 11.0 0.0 0.073 11.0 0.0 1.0 1 0 0 1 1 1 0 Prominin DUF1351 PF07083.11 GAP84461.1 - 0.11 12.3 0.5 0.15 11.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) PKcGMP_CC PF16808.5 GAP84461.1 - 0.12 12.2 9.5 14 5.7 1.8 3.2 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GMC_oxred_N PF00732.19 GAP84463.1 - 1.4e-52 178.9 0.0 2e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP84463.1 - 1e-29 103.9 0.1 1.8e-29 103.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GIDA PF01134.22 GAP84463.1 - 6.3e-09 35.4 0.3 0.0016 17.6 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 GAP84463.1 - 7.9e-08 32.3 0.5 0.00017 21.3 0.0 2.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP84463.1 - 8e-08 31.8 0.1 0.0014 17.8 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 GAP84463.1 - 2.3e-06 26.6 0.0 0.0025 16.6 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 GAP84463.1 - 5.3e-06 25.9 0.0 0.00081 18.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAP84463.1 - 1.6e-05 24.2 0.1 2.3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAP84463.1 - 2.4e-05 23.8 0.0 0.063 12.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAP84463.1 - 4.8e-05 22.9 0.4 0.0028 17.1 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP84463.1 - 6e-05 23.2 0.1 0.00017 21.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAP84463.1 - 0.0071 16.3 0.2 0.4 10.6 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 GAP84463.1 - 0.038 12.8 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 GAP84463.1 - 0.042 14.4 0.1 0.64 10.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Myb_DNA-bind_3 PF12776.7 GAP84463.1 - 0.055 14.5 0.1 0.13 13.2 0.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Thi4 PF01946.17 GAP84463.1 - 0.07 12.4 0.1 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 GAP84463.1 - 0.16 11.2 0.0 0.38 10.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Abhydrolase_1 PF00561.20 GAP84465.1 - 2.1e-19 70.2 0.0 5.6e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP84465.1 - 5.6e-14 53.3 0.2 8e-14 52.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP84465.1 - 1.1e-13 51.0 0.0 1.6e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 GAP84465.1 - 8.2e-06 25.1 0.0 1.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.14 GAP84465.1 - 0.00039 19.2 0.0 0.00058 18.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family UPF0227 PF05728.12 GAP84465.1 - 0.0083 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.13 GAP84465.1 - 0.036 13.9 0.0 0.091 12.6 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.13 GAP84465.1 - 0.054 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.11 GAP84465.1 - 0.083 12.2 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PAF-AH_p_II PF03403.13 GAP84465.1 - 0.093 11.2 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.25 GAP84465.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Pex24p PF06398.11 GAP84466.1 - 0.033 13.2 0.4 0.078 12.0 0.0 1.7 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin TPR_10 PF13374.6 GAP84467.1 - 6.8e-29 98.9 17.2 2.3e-10 40.0 0.1 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAP84467.1 - 1.5e-28 98.9 20.3 8.1e-13 48.5 0.3 5.5 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 GAP84467.1 - 5.3e-07 29.2 15.4 0.64 10.2 0.1 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat NB-ARC PF00931.22 GAP84467.1 - 1.9e-06 27.3 0.0 3.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 GAP84467.1 - 4.4e-05 23.3 17.3 6.5 7.1 1.5 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 GAP84467.1 - 0.00023 21.8 0.3 0.00083 20.0 0.1 2.0 2 0 0 2 2 1 1 Alpha/beta hydrolase family TPR_14 PF13428.6 GAP84467.1 - 0.0016 19.1 13.0 0.59 11.1 0.1 6.4 3 2 4 7 7 6 1 Tetratricopeptide repeat NACHT PF05729.12 GAP84467.1 - 0.0016 18.4 0.0 0.017 15.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 GAP84467.1 - 0.0054 17.0 0.0 0.02 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.28 GAP84467.1 - 0.011 15.6 12.9 4.1 7.4 0.5 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_16 PF13191.6 GAP84467.1 - 0.016 15.6 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain PGAP1 PF07819.13 GAP84467.1 - 0.032 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 GAP84467.1 - 0.032 13.9 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold TPR_4 PF07721.14 GAP84467.1 - 0.035 14.7 13.0 24 5.9 0.1 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TniB PF05621.11 GAP84467.1 - 0.041 13.3 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein DUF915 PF06028.11 GAP84467.1 - 0.045 13.1 0.0 0.32 10.3 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PilW PF16074.5 GAP84467.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Type IV Pilus-assembly protein W AAA_24 PF13479.6 GAP84467.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PPR PF01535.20 GAP84467.1 - 0.062 13.6 0.7 13 6.3 0.0 3.5 3 0 0 3 3 3 0 PPR repeat TPR_19 PF14559.6 GAP84467.1 - 0.076 13.5 11.8 0.077 13.5 0.2 4.8 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAP84467.1 - 0.08 13.2 9.7 14 6.2 0.3 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 GAP84467.1 - 0.083 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Thioesterase PF00975.20 GAP84467.1 - 0.089 12.9 0.2 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Hydrolase_4 PF12146.8 GAP84467.1 - 0.12 11.6 0.5 0.5 9.6 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AAA_18 PF13238.6 GAP84467.1 - 0.13 12.8 0.0 0.49 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain TPR_16 PF13432.6 GAP84467.1 - 0.16 12.6 15.2 0.94 10.2 5.7 4.7 2 2 2 4 4 4 0 Tetratricopeptide repeat Baculo_LEF-10 PF07206.11 GAP84467.1 - 0.29 11.3 1.4 3.1 8.0 0.7 2.7 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) TPR_9 PF13371.6 GAP84467.1 - 5.5 7.2 15.4 7.6 6.8 0.1 5.0 3 1 3 6 6 5 0 Tetratricopeptide repeat HET PF06985.11 GAP84468.1 - 7.9e-18 65.2 1.4 2.5e-17 63.6 1.4 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.28 GAP84469.1 - 4.2e-66 223.3 0.0 5.2e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF3176 PF11374.8 GAP84470.1 - 1.7e-29 102.2 0.5 4.1e-29 100.9 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) FHA PF00498.26 GAP84471.1 - 2.7e-17 62.9 0.1 7e-17 61.5 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 GAP84471.1 - 4.7e-05 23.6 0.0 0.00016 21.9 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 GAP84471.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 YhfZ C-terminal domain DUF4715 PF15835.5 GAP84471.1 - 0.29 11.2 1.8 2.8 8.0 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) DUF4482 PF14818.6 GAP84471.1 - 2.3 9.1 13.7 1.2 10.0 1.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4482) Atg14 PF10186.9 GAP84471.1 - 5 6.1 10.5 1.3 8.1 1.7 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cu-oxidase_3 PF07732.15 GAP84472.1 - 8.5e-43 145.2 8.1 1.2e-41 141.4 0.3 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 GAP84472.1 - 4.3e-34 117.9 2.5 1.7e-32 112.8 0.1 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAP84472.1 - 2.1e-33 115.0 10.5 1.2e-30 106.0 2.3 3.8 3 1 0 3 3 3 3 Multicopper oxidase Ras PF00071.22 GAP84473.1 - 1.1e-52 178.0 0.0 1.2e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP84473.1 - 7.6e-22 77.8 0.0 1.2e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP84473.1 - 5.6e-10 38.9 0.0 1.6e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAP84473.1 - 4.5e-06 26.2 0.0 5.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 GAP84473.1 - 0.002 17.4 0.0 0.0067 15.6 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 GAP84473.1 - 0.0034 16.8 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAP84473.1 - 0.0039 17.2 0.0 0.0065 16.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAP84473.1 - 0.066 12.7 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAP84473.1 - 0.12 12.2 0.0 16 5.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_21 PF13304.6 GAP84473.1 - 0.19 11.5 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system CWC25 PF12542.8 GAP84474.1 - 1.8e-22 80.1 0.0 1.8e-22 80.1 0.0 4.1 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 GAP84474.1 - 4e-14 52.5 3.1 4e-14 52.5 3.1 4.1 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.27 GAP84475.1 - 1.7e-18 67.0 0.6 4e-18 65.9 0.1 1.9 2 0 0 2 2 2 1 PCI domain Pkinase_Tyr PF07714.17 GAP84475.1 - 0.022 14.1 0.3 0.12 11.6 0.2 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase TPR_7 PF13176.6 GAP84475.1 - 0.044 13.8 2.0 1.9 8.7 0.1 4.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAP84475.1 - 0.074 13.2 3.9 1.5 9.1 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat NUDIX PF00293.28 GAP84476.1 - 6.7e-15 55.3 0.0 9.2e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NmrA PF05368.13 GAP84477.1 - 1.5e-11 44.3 0.0 1.8e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP84477.1 - 4.7e-06 26.6 0.0 5.4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP84477.1 - 0.037 13.5 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family WD40 PF00400.32 GAP84478.1 - 2.3e-07 31.4 0.3 0.00016 22.4 0.1 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP84478.1 - 8.8e-05 22.7 0.0 0.04 14.2 0.0 3.2 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 GAP84478.1 - 0.0011 17.4 0.0 0.091 11.1 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Rax2 PF12768.7 GAP84480.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity OATP PF03137.20 GAP84480.1 - 0.19 10.0 0.6 0.26 9.5 0.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Presenilin PF01080.17 GAP84480.1 - 1.4 7.6 6.4 2.4 6.9 6.4 1.3 1 0 0 1 1 1 0 Presenilin EphA2_TM PF14575.6 GAP84480.1 - 8.3 7.4 8.2 13 6.8 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Activator_LAG-3 PF11498.8 GAP84480.1 - 9.7 5.0 36.3 17 4.2 36.3 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PFK PF00365.20 GAP84481.1 - 1.5e-188 624.9 0.5 6.1e-106 353.9 0.8 2.2 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 GAP84481.1 - 0.028 14.0 0.1 0.31 10.6 0.1 2.7 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain Med17 PF10156.9 GAP84482.1 - 4e-82 276.4 0.0 5e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex AC_N PF16214.5 GAP84484.1 - 3.5 6.7 4.7 5.7 6.0 4.7 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region CBFD_NFYB_HMF PF00808.23 GAP84485.1 - 7.8e-18 64.5 0.2 1.3e-17 63.8 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAP84485.1 - 8.3e-06 26.2 0.2 2.1e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 adh_short PF00106.25 GAP84486.1 - 9.4e-42 142.7 0.0 1.1e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84486.1 - 3.4e-32 111.9 0.1 4.2e-32 111.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP84486.1 - 5.1e-10 39.5 0.1 7.2e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAP84486.1 - 0.042 13.7 0.5 0.1 12.4 0.5 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 GAP84486.1 - 0.046 13.2 0.3 0.4 10.1 0.3 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 GAP84488.1 - 2.3e-41 141.9 32.8 2.3e-41 141.9 32.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3405 PF11885.8 GAP84489.1 - 2.5e-205 683.0 0.7 1.6e-204 680.3 0.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Palm_thioest PF02089.15 GAP84491.1 - 6.2e-08 32.8 0.0 2e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 GAP84491.1 - 1.9e-07 31.1 0.1 3.5e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAP84491.1 - 3.4e-06 27.8 2.7 5.2e-06 27.2 2.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 GAP84491.1 - 1.1e-05 25.1 0.0 3.5e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 GAP84491.1 - 2.3e-05 24.2 1.2 0.00018 21.2 1.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 GAP84491.1 - 0.00099 18.4 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Glyco_trans_4_4 PF13579.6 GAP84491.1 - 0.0041 17.6 1.8 0.047 14.1 0.3 2.3 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Lipase_2 PF01674.18 GAP84491.1 - 0.0051 16.3 0.1 0.047 13.2 0.0 2.3 3 0 0 3 3 3 1 Lipase (class 2) DUF900 PF05990.12 GAP84491.1 - 0.016 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 GAP84491.1 - 0.03 13.6 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 GAP84491.1 - 0.09 12.0 0.1 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Enoyl_reductase PF12241.8 GAP84491.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Peptidase_S10 PF00450.22 GAP84493.1 - 5e-113 378.7 0.1 6.5e-113 378.3 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase zf-MIZ PF02891.20 GAP84494.1 - 1.3e-07 31.2 5.3 1.8e-06 27.6 5.3 2.4 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger Imm41 PF15592.6 GAP84494.1 - 0.072 13.4 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 41 zf-Nse PF11789.8 GAP84494.1 - 0.086 12.7 1.2 0.25 11.2 1.2 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SAM_2 PF07647.17 GAP84495.1 - 5.9e-14 51.9 0.0 1.2e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 GAP84495.1 - 9.9e-14 50.9 0.1 3.5e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 GAP84495.1 - 8.9e-12 44.4 0.0 1.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 GAP84495.1 - 4.8e-10 39.9 0.0 3.3e-09 37.2 0.0 2.3 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 GAP84495.1 - 0.00014 21.5 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 GAP84495.1 - 0.001 19.5 0.2 0.0025 18.2 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 GAP84495.1 - 0.054 13.8 0.0 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain SAM_1 PF00536.30 GAP84495.1 - 0.065 13.7 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Formyl_trans_N PF00551.19 GAP84496.1 - 3e-18 66.2 0.0 4.3e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase HABP4_PAI-RBP1 PF04774.15 GAP84497.1 - 0.055 14.3 5.6 0.17 12.7 5.6 1.7 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family DUF1279 PF06916.13 GAP84498.1 - 2.8e-25 88.7 0.0 1.4e-24 86.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) GMC_oxred_N PF00732.19 GAP84499.1 - 5.7e-59 199.9 0.0 7e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP84499.1 - 4.3e-30 105.1 0.0 7.5e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAP84499.1 - 2.7e-08 33.3 3.0 0.003 16.7 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAP84499.1 - 5e-06 26.0 1.8 0.023 14.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP84499.1 - 7e-06 25.5 0.5 0.0045 16.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP84499.1 - 1.2e-05 25.0 4.9 9.5e-05 22.1 4.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP84499.1 - 2.1e-05 24.7 0.6 6.6e-05 23.1 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAP84499.1 - 0.00016 22.2 3.5 0.061 13.9 0.3 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAP84499.1 - 0.00059 19.0 0.2 0.0011 18.1 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAP84499.1 - 0.0024 17.2 1.3 0.0061 15.8 0.2 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 GAP84499.1 - 0.0055 15.5 1.2 0.032 12.9 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein TrkA_N PF02254.18 GAP84499.1 - 0.029 14.6 0.4 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 GAP84499.1 - 0.076 13.0 2.5 0.15 12.0 0.2 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAP84499.1 - 0.11 11.7 0.3 8.9 5.3 0.1 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 GAP84499.1 - 0.12 11.2 0.4 0.23 10.2 0.4 1.4 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 GAP84499.1 - 0.91 8.8 8.2 0.94 8.8 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase MARVEL PF01284.23 GAP84500.1 - 6.7e-19 68.3 18.4 8.2e-19 68.1 18.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.12 GAP84500.1 - 7.8 6.1 12.1 49 3.5 9.8 2.3 2 0 0 2 2 2 0 SUR7/PalI family Glyco_hydro_43 PF04616.14 GAP84501.1 - 1.8e-70 237.6 1.3 2.3e-70 237.2 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAP84501.1 - 6.7e-15 55.4 0.0 1.7e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Sugar_tr PF00083.24 GAP84502.1 - 2e-102 343.4 15.4 2.3e-102 343.2 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP84502.1 - 2.7e-24 85.8 31.7 3.4e-23 82.2 23.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAP84502.1 - 1.2e-06 27.3 1.0 1.7e-06 26.7 1.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 GAP84503.1 - 6.8e-16 58.1 1.0 1.2e-15 57.3 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAP84503.1 - 6.3e-08 32.7 11.8 0.00043 20.6 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP84503.1 - 0.00048 20.7 10.0 0.19 12.7 2.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 GAP84503.1 - 0.037 14.6 0.3 0.1 13.2 0.3 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 GAP84503.1 - 2.6 8.2 6.5 17 5.5 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger AMPK1_CBM PF16561.5 GAP84504.1 - 3.6e-20 72.0 0.1 7e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 GAP84504.1 - 0.14 12.7 0.2 0.38 11.4 0.2 1.7 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) DHO_dh PF01180.21 GAP84505.1 - 7.3e-17 61.5 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase zf-RING_UBOX PF13445.6 GAP84505.1 - 2e-06 27.7 8.2 2e-05 24.5 4.3 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAP84505.1 - 1.6e-05 24.8 7.4 2.9e-05 23.9 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAP84505.1 - 1.6e-05 24.6 9.3 3.7e-05 23.5 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP84505.1 - 5.3e-05 23.5 10.3 0.00012 22.3 10.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAP84505.1 - 0.00025 20.8 7.4 0.001 18.9 4.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP84505.1 - 0.00054 19.8 8.9 0.0012 18.6 8.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAP84505.1 - 0.012 15.8 7.8 0.11 12.7 8.5 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAP84505.1 - 0.96 9.4 12.2 11 5.9 11.8 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 GAP84505.1 - 3 8.1 5.4 2.3 8.4 3.1 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 GAP84505.1 - 9.4 6.6 7.6 32 4.9 7.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain CFEM PF05730.11 GAP84506.1 - 0.092 12.9 11.3 0.21 11.7 11.2 1.8 1 1 0 1 1 1 0 CFEM domain Oxidored_q6 PF01058.22 GAP84507.1 - 7e-22 77.7 0.0 1.1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit F-box-like PF12937.7 GAP84509.1 - 0.013 15.4 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 F-box-like CTP_transf_like PF01467.26 GAP84510.1 - 4.4e-30 104.8 0.0 7e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Tctex-1 PF03645.13 GAP84511.1 - 1.1e-36 125.2 0.0 1.2e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 GAP84512.1 - 0.00014 22.2 2.1 0.0016 18.8 0.2 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF202) HECT PF00632.25 GAP84515.1 - 6e-95 318.3 0.0 8.2e-95 317.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 GAP84515.1 - 1.1e-33 115.0 24.2 6.9e-13 48.4 6.3 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 GAP84515.1 - 4.2e-19 68.7 0.0 1.1e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain SUIM_assoc PF16619.5 GAP84515.1 - 6.5 6.9 12.0 2.3 8.4 6.2 2.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Helo_like_N PF17111.5 GAP84516.1 - 0.00016 21.1 0.1 0.00031 20.2 0.1 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 GAP84516.1 - 0.00049 20.3 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases MLD PF11647.8 GAP84516.1 - 0.03 14.6 1.6 9.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Membrane Localization Domain TPR_12 PF13424.6 GAP84516.1 - 0.49 10.7 9.9 0.13 12.5 1.5 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.19 GAP84517.1 - 5.9e-45 152.8 0.0 1e-44 152.0 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP84517.1 - 0.0022 17.6 0.0 0.005 16.5 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.6 GAP84517.1 - 0.0069 16.8 0.0 0.086 13.3 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 GAP84517.1 - 0.0085 16.2 0.0 0.19 11.8 0.0 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 GAP84517.1 - 0.056 13.5 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 GAP84517.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XdhC_C PF13478.6 GAP84517.1 - 0.09 13.3 0.0 0.73 10.3 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain SNF2_N PF00176.23 GAP84518.1 - 6.3e-22 77.8 0.0 1.2e-21 76.9 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 GAP84518.1 - 1.2e-09 38.4 0.0 4.3e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAP84518.1 - 0.00043 20.6 0.1 0.0013 19.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_11 PF13086.6 GAP84518.1 - 0.027 14.2 0.2 17 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain CDPS PF16715.5 GAP84518.1 - 0.045 13.4 0.1 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 Cyclodipeptide synthase MFS_1 PF07690.16 GAP84519.1 - 1e-35 123.3 28.8 1e-35 123.3 28.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Cu-oxidase_3 PF07732.15 GAP84520.1 - 7.1e-41 139.0 1.8 4.2e-40 136.5 1.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAP84520.1 - 7.1e-40 135.9 8.5 1.3e-37 128.6 0.4 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 GAP84520.1 - 6.5e-36 123.8 1.2 6.5e-35 120.6 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase HAD_2 PF13419.6 GAP84522.1 - 0.00044 20.4 0.0 0.00076 19.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP84522.1 - 0.085 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Ribosomal_L5e PF17144.4 GAP84523.1 - 9.1e-81 269.6 0.1 1.5e-80 268.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 GAP84523.1 - 4.4e-35 120.5 9.2 4.4e-35 120.5 9.2 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 GAP84523.1 - 0.021 15.2 1.7 0.026 14.9 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast LRR_6 PF13516.6 GAP84525.1 - 0.079 13.0 11.1 3.9 7.8 0.1 6.3 6 0 0 6 6 6 0 Leucine Rich repeat U3_snoRNA_assoc PF08297.11 GAP84525.1 - 0.088 13.5 10.0 0.38 11.5 10.0 2.1 1 0 0 1 1 1 0 U3 snoRNA associated His_Phos_1 PF00300.22 GAP84528.1 - 1.2e-17 64.3 0.0 1.5e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MutS_II PF05188.17 GAP84528.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 MutS domain II SWIRM-assoc_2 PF16496.5 GAP84529.1 - 0.21 10.4 6.0 0.37 9.6 6.0 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Spem1 PF15670.5 GAP84529.1 - 2.2 7.8 6.6 3.8 7.0 6.6 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 adh_short PF00106.25 GAP84530.1 - 9.2e-18 64.4 0.1 1.6e-09 37.5 0.1 3.2 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84530.1 - 4e-07 29.8 0.4 0.0067 16.0 0.4 3.1 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Voldacs PF03517.13 GAP84530.1 - 0.0026 17.9 0.6 0.065 13.4 0.0 2.2 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling KR PF08659.10 GAP84530.1 - 0.0034 17.3 0.2 0.0072 16.3 0.2 1.5 1 0 0 1 1 1 1 KR domain ApbA PF02558.16 GAP84530.1 - 0.05 13.2 0.2 0.11 12.1 0.2 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sporozoite_P67 PF05642.11 GAP84530.1 - 0.22 9.6 1.0 3.4 5.7 0.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF3439 PF11921.8 GAP84530.1 - 1.2 9.2 5.8 2.7 8.0 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_S10 PF00450.22 GAP84531.1 - 4.8e-96 322.7 0.1 5.7e-96 322.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase TFIIA PF03153.13 GAP84532.1 - 0.44 10.5 5.1 0.61 10.0 5.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUR7 PF06687.12 GAP84535.1 - 1.4e-16 60.8 10.6 1.4e-16 60.8 10.6 1.7 1 1 1 2 2 2 1 SUR7/PalI family DuoxA PF10204.9 GAP84535.1 - 1.1 8.2 9.4 0.42 9.6 6.6 1.7 2 0 0 2 2 2 0 Dual oxidase maturation factor ECSCR PF15820.5 GAP84535.1 - 6.9 6.5 12.5 20 5.1 5.6 3.0 2 1 1 3 3 3 0 Endothelial cell-specific chemotaxis regulator FACT-Spt16_Nlob PF14826.6 GAP84536.1 - 2e-57 193.5 0.6 2e-57 193.5 0.6 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 GAP84536.1 - 1.6e-56 190.7 0.1 1.6e-56 190.7 0.1 3.3 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 GAP84536.1 - 1.7e-26 93.2 0.0 3.2e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 GAP84536.1 - 2.5e-16 59.9 0.7 1e-15 57.9 0.1 2.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like MFS_1 PF07690.16 GAP84537.1 - 7.5e-26 90.9 45.9 9.1e-22 77.4 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PC_rep PF01851.22 GAP84537.1 - 4.9 7.8 6.2 4.2 8.0 0.2 2.7 2 0 0 2 2 2 0 Proteasome/cyclosome repeat Pkinase PF00069.25 GAP84538.1 - 3.1e-08 33.3 0.0 4.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 GAP84538.1 - 0.00057 19.3 0.0 0.00088 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 GAP84538.1 - 0.00063 19.1 0.0 0.00093 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP84538.1 - 0.0086 16.0 0.1 0.016 15.1 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DnaB PF00772.21 GAP84538.1 - 0.2 11.7 0.0 0.49 10.5 0.0 1.7 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain NACHT_N PF17100.5 GAP84539.1 - 3.1e-66 223.4 0.0 4.8e-66 222.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 GAP84539.1 - 2.8e-42 141.9 20.4 1.3e-06 29.0 0.1 11.5 12 0 0 12 12 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP84539.1 - 7.8e-20 71.0 0.4 0.046 14.0 0.0 8.7 2 2 8 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 GAP84539.1 - 5.8e-13 49.1 0.2 1.1e-12 48.2 0.2 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 GAP84539.1 - 9.7e-08 31.8 0.5 6.3 6.9 0.0 7.8 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 GAP84539.1 - 1.4e-07 30.8 0.2 0.39 9.6 0.0 5.3 1 1 6 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAP84539.1 - 6.3e-07 29.5 0.0 0.5 10.2 0.0 4.4 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 GAP84539.1 - 0.0001 21.8 2.7 6.8 5.9 0.0 5.8 3 2 4 7 7 7 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 GAP84539.1 - 0.0027 16.4 1.8 1.9 7.0 0.2 4.2 2 1 1 4 4 4 1 Nucleoporin Nup120/160 AAA_16 PF13191.6 GAP84539.1 - 0.016 15.6 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Proteasome_A_N PF10584.9 GAP84539.1 - 0.029 14.1 2.8 38 4.1 0.0 5.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF1513 PF07433.11 GAP84539.1 - 0.065 12.3 0.4 10 5.1 0.0 3.6 3 1 0 4 4 4 0 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.11 GAP84539.1 - 0.074 11.8 0.0 4.4 5.9 0.0 3.2 1 1 1 3 3 3 0 Nup133 N terminal like PIF1 PF05970.14 GAP84539.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase PQQ_2 PF13360.6 GAP84539.1 - 0.13 11.8 10.7 4.2 6.9 4.1 4.2 1 1 3 4 4 4 0 PQQ-like domain ResIII PF04851.15 GAP84539.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GAP84539.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 GAP84540.1 - 1.8e-29 102.8 0.0 3e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2802 PF10975.8 GAP84540.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) ketoacyl-synt PF00109.26 GAP84541.1 - 1.8e-76 257.0 0.4 5.3e-76 255.5 0.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAP84541.1 - 1.1e-36 125.4 0.8 2.7e-36 124.1 0.8 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 GAP84541.1 - 2.1e-24 86.6 0.2 2.9e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain HTH_51 PF18558.1 GAP84541.1 - 1.1e-17 63.6 0.0 3.7e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain PS-DH PF14765.6 GAP84541.1 - 3e-17 62.8 0.0 6.4e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 GAP84541.1 - 5.2e-15 55.8 7.1 1.7e-09 37.8 1.7 4.3 3 1 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 GAP84541.1 - 9.8e-14 51.9 0.0 2.6e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 GAP84541.1 - 5e-13 49.2 0.3 1.5e-12 47.7 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 GAP84541.1 - 2.2e-11 43.9 0.0 9.5e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP84541.1 - 5.7e-11 43.0 0.0 2e-10 41.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP84541.1 - 1.4e-07 32.1 0.0 4.6e-07 30.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP84541.1 - 3.3e-07 30.2 0.0 8.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 GAP84541.1 - 8.1e-07 28.7 0.6 2.4e-06 27.1 0.3 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 GAP84541.1 - 1.1e-05 25.9 0.0 3.3e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_33 PF10017.9 GAP84541.1 - 0.001 18.3 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DUF1041 PF06292.17 GAP84541.1 - 0.13 12.7 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) p450 PF00067.22 GAP84542.1 - 8.8e-51 173.1 0.0 1.3e-50 172.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 GAP84543.1 - 6.6e-52 176.7 2.9 6.2e-51 173.5 2.9 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP84543.1 - 8.7e-35 120.4 0.0 1.4e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAP84543.1 - 2.5e-06 26.9 0.3 0.015 14.5 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP84543.1 - 1.1e-05 24.7 0.6 0.03 13.4 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAP84543.1 - 0.00058 20.0 0.7 0.0018 18.5 0.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAP84543.1 - 0.0016 17.7 0.1 0.0084 15.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP84543.1 - 0.013 15.2 4.0 0.19 11.3 3.9 2.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAP84543.1 - 0.1 11.6 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 GAP84543.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Maf1 PF09174.10 GAP84544.1 - 4.2e-60 202.8 0.0 6.1e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 GAP84545.1 - 2.6e-51 173.3 1.0 3e-51 173.1 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 GAP84545.1 - 0.034 14.9 0.1 0.057 14.2 0.1 1.4 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Aldo_ket_red PF00248.21 GAP84546.1 - 2e-10 40.4 0.0 2.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.14 GAP84547.1 - 8.6e-09 35.1 0.0 4.3e-05 23.0 0.0 2.6 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 GAP84547.1 - 1.3e-07 31.3 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAP84547.1 - 3.2e-06 27.3 5.5 0.0049 16.8 1.3 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 GAP84547.1 - 3.3e-05 23.6 0.1 0.0077 15.9 0.1 2.4 1 1 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 GAP84547.1 - 7.5e-05 22.1 0.0 0.00014 21.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP84547.1 - 0.015 14.1 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RRP7 PF12923.7 GAP84549.1 - 5.7e-32 110.3 13.2 5.7e-32 110.3 13.2 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 GAP84549.1 - 3.8e-19 69.1 0.0 6.3e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain Ehbp PF10622.9 GAP84549.1 - 0.058 13.4 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) MFS_1 PF07690.16 GAP84550.1 - 8.8e-54 182.8 44.8 5.7e-43 147.2 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAP84550.1 - 1.1e-09 37.3 4.2 1.1e-09 37.3 4.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 GAP84550.1 - 0.033 12.5 8.7 0.54 8.5 3.0 3.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ADH_zinc_N PF00107.26 GAP84551.1 - 3.5e-07 30.3 0.0 5.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP84551.1 - 4.7e-06 26.4 0.0 8.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAP84551.1 - 9e-05 23.5 0.0 0.00019 22.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 GAP84552.1 - 1.4e-07 30.8 0.0 2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S32 PF05579.13 GAP84552.1 - 0.13 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Trp_oprn_chp PF09534.10 GAP84553.1 - 3.7 7.3 6.6 24 4.6 0.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sugar_tr PF00083.24 GAP84554.1 - 4.1e-75 253.4 20.2 5e-75 253.1 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP84554.1 - 2.4e-23 82.6 23.9 3.6e-23 82.1 23.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 GAP84554.1 - 0.043 13.6 0.2 0.18 11.6 0.2 2.1 1 0 0 1 1 1 0 Bacteriophage holin family HP1 eIF-5_eIF-2B PF01873.17 GAP84556.1 - 3.1e-41 139.9 0.3 4.6e-41 139.4 0.3 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 ZapA PF05164.13 GAP84556.1 - 0.0046 17.4 0.1 0.01 16.2 0.1 1.6 1 0 0 1 1 1 1 Cell division protein ZapA TF_Zn_Ribbon PF08271.12 GAP84556.1 - 0.033 13.7 0.5 0.068 12.7 0.5 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 GAP84556.1 - 0.64 10.4 6.2 1.2 9.6 0.2 2.8 1 1 1 2 2 2 0 Archaeal TRASH domain HET PF06985.11 GAP84557.1 - 3e-11 43.9 6.1 3.3e-10 40.5 0.9 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3425 PF11905.8 GAP84559.1 - 6.4e-16 58.5 2.1 7.6e-16 58.2 0.8 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAP84559.1 - 0.02 15.0 10.6 0.13 12.4 10.6 2.0 1 1 0 1 1 1 0 bZIP transcription factor DUF1003 PF06210.11 GAP84559.1 - 1.2 9.3 3.4 2.8 8.1 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) HSCB_C PF07743.13 GAP84559.1 - 2.4 8.7 5.4 4.1 7.9 5.4 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain TSC22 PF01166.18 GAP84559.1 - 2.4 8.5 4.3 28 5.1 0.1 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family Wbp11 PF09429.10 GAP84559.1 - 2.6 8.5 8.1 5.1 7.6 8.1 1.4 1 0 0 1 1 1 0 WW domain binding protein 11 bZIP_2 PF07716.15 GAP84559.1 - 3.4 7.8 13.9 2.6 8.2 7.7 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Macoilin PF09726.9 GAP84559.1 - 4.4 5.7 8.2 6.8 5.1 8.2 1.1 1 0 0 1 1 1 0 Macoilin family PseudoU_synth_2 PF00849.22 GAP84560.1 - 3.9e-29 101.8 0.0 5.8e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Auto_anti-p27 PF06677.12 GAP84560.1 - 0.069 13.3 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 4HBT_2 PF13279.6 GAP84561.1 - 1.3e-08 35.4 0.1 1.6e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 GAP84561.1 - 6.9e-08 32.7 0.0 9.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 GAP84561.1 - 1.3e-06 27.9 0.9 3.2e-06 26.6 0.7 1.6 2 0 0 2 2 2 1 Acyl-ACP thioesterase Epsilon_antitox PF08998.11 GAP84561.1 - 0.099 12.9 0.2 0.9 9.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial epsilon antitoxin COX_ARM PF06481.14 GAP84561.1 - 0.27 11.2 1.6 0.41 10.6 0.2 2.0 2 0 0 2 2 2 0 COX Aromatic Rich Motif GFO_IDH_MocA PF01408.22 GAP84562.1 - 7.3e-14 52.6 0.1 2.8e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAP84562.1 - 0.0018 18.3 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Transglut_core PF01841.19 GAP84562.1 - 0.062 13.8 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily NmrA PF05368.13 GAP84563.1 - 2.5e-24 86.1 0.0 3.2e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP84563.1 - 8.3e-16 58.4 0.7 3.9e-15 56.2 0.7 1.9 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAP84563.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 GAP84563.1 - 0.043 13.9 0.1 0.074 13.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 GAP84563.1 - 0.059 12.8 0.9 0.13 11.7 0.1 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3394 PF11874.8 GAP84563.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Acetyltransf_10 PF13673.7 GAP84564.1 - 0.0014 18.5 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP84564.1 - 0.022 15.0 0.1 0.036 14.3 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF5386 PF17360.2 GAP84565.1 - 0.13 12.2 0.0 4.2 7.3 0.0 2.7 1 1 2 3 3 3 0 Family of unknown function (DUF5386) DUF3328 PF11807.8 GAP84566.1 - 1e-37 130.1 1.0 1.3e-37 129.7 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) GFA PF04828.14 GAP84567.1 - 2e-23 82.5 0.0 2.7e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 GAP84567.1 - 0.085 12.9 1.6 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon NMD3 PF04981.13 GAP84567.1 - 0.18 11.2 0.2 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 NMD3 family Zn_ribbon_recom PF13408.6 GAP84567.1 - 0.35 11.4 0.0 0.35 11.4 0.0 2.5 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain MBF1 PF08523.10 GAP84569.1 - 2.2e-23 82.5 1.2 4.4e-23 81.5 1.2 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 GAP84569.1 - 2.8e-09 36.9 0.0 4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 GAP84569.1 - 0.00064 20.0 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 GAP84569.1 - 0.093 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CDT1_C PF16679.5 GAP84570.1 - 3e-17 62.8 0.1 3e-17 62.8 0.1 2.9 4 0 0 4 4 4 1 DNA replication factor Cdt1 C-terminal domain Dicty_REP PF05086.12 GAP84570.1 - 0.0014 16.8 10.4 0.012 13.6 4.2 2.1 2 0 0 2 2 2 2 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 GAP84570.1 - 0.0014 18.6 21.5 0.12 12.3 12.6 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3439) Mucin PF01456.17 GAP84570.1 - 0.54 10.3 29.8 0.072 13.1 10.8 3.0 3 0 0 3 3 3 0 Mucin-like glycoprotein Tir_receptor_C PF07489.11 GAP84570.1 - 1 9.3 10.9 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus AT_hook PF02178.19 GAP84570.1 - 1.3 9.1 9.6 8.4 6.6 9.6 2.5 1 0 0 1 1 1 0 AT hook motif AJAP1_PANP_C PF15298.6 GAP84570.1 - 6.1 7.0 14.6 11 6.1 8.3 2.5 2 0 0 2 2 2 0 AJAP1/PANP C-terminus GST_N_3 PF13417.6 GAP84574.1 - 0.017 15.5 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Aft1_HRR PF11787.8 GAP84575.1 - 4.3e-26 91.9 4.2 4.3e-26 91.9 4.2 3.5 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_HRA PF11786.8 GAP84575.1 - 7.2e-24 83.9 9.6 7.2e-24 83.9 9.6 3.4 3 1 0 3 3 3 1 Aft1 HRA domain Aft1_OSA PF11785.8 GAP84575.1 - 1.4e-12 47.8 6.2 1.4e-12 47.8 6.2 4.0 5 0 0 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 GAP84575.1 - 4.9e-12 45.8 6.7 7.7e-12 45.1 6.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAP84575.1 - 2.2e-05 24.5 6.4 4e-05 23.6 6.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAP84575.1 - 0.0076 16.8 3.3 0.0076 16.8 3.3 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor HALZ PF02183.18 GAP84575.1 - 0.09 13.0 0.2 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Macoilin PF09726.9 GAP84575.1 - 0.23 10.0 7.3 0.31 9.6 7.3 1.1 1 0 0 1 1 1 0 Macoilin family MIS13 PF08202.11 GAP84576.1 - 3e-61 207.3 0.6 3e-61 207.3 0.6 2.1 2 0 0 2 2 2 1 Mis12-Mtw1 protein family XhlA PF10779.9 GAP84576.1 - 0.31 11.3 2.9 18 5.6 0.3 2.5 2 0 0 2 2 2 0 Haemolysin XhlA ABC_tran_CTD PF16326.5 GAP84576.1 - 9.4 6.6 7.4 3.8 7.8 1.1 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain Sdh5 PF03937.16 GAP84577.1 - 9.1e-25 86.4 0.1 1.8e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase NAM-associated PF14303.6 GAP84577.1 - 0.15 12.8 3.5 0.27 11.9 3.5 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Med3 PF11593.8 GAP84577.1 - 5.7 6.0 9.4 7.7 5.6 9.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal EMP24_GP25L PF01105.24 GAP84578.1 - 2.4e-40 138.4 0.0 3e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 GAP84578.1 - 0.026 12.7 1.0 0.034 12.3 1.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA zf-U1 PF06220.12 GAP84579.1 - 6.7e-22 77.0 3.4 1e-21 76.4 3.4 1.3 1 0 0 1 1 1 1 U1 zinc finger DUF2959 PF11172.8 GAP84580.1 - 0.17 12.0 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) SpoU_methylase PF00588.19 GAP84583.1 - 5.6e-25 88.2 0.0 9e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 GAP84583.1 - 5.8e-08 32.9 0.0 9.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Ring_hydroxyl_B PF00866.18 GAP84583.1 - 0.0041 17.2 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Ring hydroxylating beta subunit HET PF06985.11 GAP84584.1 - 1.1e-25 90.7 0.0 2.1e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-PHD-like PF15446.6 GAP84585.1 - 7.7e-67 224.1 10.1 1.4e-66 223.3 10.1 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 GAP84585.1 - 2.1e-48 164.9 0.1 3.1e-48 164.3 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP84585.1 - 8.7e-18 64.7 0.0 2.2e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 GAP84585.1 - 1.7e-07 30.8 1.3 5.7e-07 29.0 1.3 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 GAP84585.1 - 3.1e-05 24.0 0.0 6.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 GAP84585.1 - 3.1e-05 23.8 0.1 0.01 15.7 0.1 3.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 GAP84585.1 - 0.0013 18.6 4.3 0.0013 18.6 4.3 4.1 4 1 1 5 5 5 2 PHD-finger PHD_2 PF13831.6 GAP84585.1 - 0.0071 15.9 1.0 0.0071 15.9 1.0 2.9 4 0 0 4 4 4 1 PHD-finger Zf_RING PF16744.5 GAP84585.1 - 0.0097 16.0 9.5 0.014 15.5 0.3 3.0 2 1 0 2 2 2 1 KIAA1045 RING finger ADK_lid PF05191.14 GAP84585.1 - 1.7 8.7 5.8 0.4 10.7 0.1 2.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 GAP84585.1 - 1.7 8.6 5.5 0.85 9.6 2.3 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 adh_short PF00106.25 GAP84587.1 - 8.1e-38 129.8 0.1 1.6e-37 128.8 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84587.1 - 1.5e-27 96.7 0.0 2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAP84587.1 - 3.7e-07 29.8 0.0 2e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAP84587.1 - 7.3e-07 29.3 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 GAP84587.1 - 4.9e-06 25.8 0.0 8.1e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAP84587.1 - 1e-05 25.5 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAP84587.1 - 0.016 14.8 0.0 0.086 12.4 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family NACHT PF05729.12 GAP84588.1 - 3.8e-09 36.7 0.1 1.3e-08 34.9 0.1 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP84588.1 - 0.0025 18.2 3.1 0.0033 17.8 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAP84588.1 - 0.0052 17.1 0.2 0.029 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain TMEM154 PF15102.6 GAP84588.1 - 0.016 15.1 0.0 0.05 13.5 0.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 GAP84588.1 - 0.031 13.7 2.2 0.076 12.4 2.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain cobW PF02492.19 GAP84588.1 - 0.075 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 GAP84588.1 - 0.08 13.5 0.5 0.38 11.3 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 GAP84588.1 - 0.099 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF5531 PF17671.1 GAP84588.1 - 0.38 10.6 3.7 13 5.7 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5531) MDFI PF15316.6 GAP84588.1 - 3.1 7.9 8.2 5.6 7.0 0.6 2.7 2 0 0 2 2 2 0 MyoD family inhibitor DUF1664 PF07889.12 GAP84588.1 - 7.1 6.7 11.6 8.9 6.4 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 GAP84588.1 - 7.5 6.9 7.8 5.5 7.3 0.3 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Acetyltransf_3 PF13302.7 GAP84589.1 - 1.5e-11 45.2 0.0 2.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP84589.1 - 3.3e-07 30.6 0.0 4.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Cutinase PF01083.22 GAP84590.1 - 2.5e-31 109.0 1.1 3e-31 108.8 1.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAP84590.1 - 0.00048 19.7 0.1 0.00065 19.3 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 GAP84590.1 - 0.0091 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Palm_thioest PF02089.15 GAP84590.1 - 0.041 13.7 0.0 0.055 13.3 0.0 1.3 1 1 0 1 1 1 0 Palmitoyl protein thioesterase PMM PF03332.13 GAP84590.1 - 0.074 12.8 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase Abhydrolase_6 PF12697.7 GAP84590.1 - 0.1 13.2 0.1 0.14 12.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mur_ligase_M PF08245.12 GAP84592.1 - 0.00013 22.0 0.0 0.0003 20.9 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Methyltransf_25 PF13649.6 GAP84593.1 - 8.5e-09 36.0 0.0 4.9e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP84593.1 - 1.7e-07 31.2 0.0 2.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP84593.1 - 9.3e-07 29.5 0.0 1.9e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP84593.1 - 0.0013 19.3 0.0 0.0043 17.7 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 GAP84593.1 - 0.0017 17.9 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 GAP84593.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Allantoicase PF03561.15 GAP84593.1 - 0.016 15.2 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Allantoicase repeat DUF218 PF02698.17 GAP84594.1 - 3.6e-05 23.8 0.0 4.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Zn_clus PF00172.18 GAP84596.1 - 8.4e-05 22.6 9.9 8.4e-05 22.6 9.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAP84596.1 - 0.00085 18.2 0.2 0.002 17.0 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain SprB PF13573.6 GAP84596.1 - 0.1 12.4 0.2 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 SprB repeat CorA PF01544.18 GAP84597.1 - 0.00025 20.4 0.2 0.00072 19.0 0.0 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SUR7 PF06687.12 GAP84597.1 - 0.044 13.4 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 SUR7/PalI family Pkinase PF00069.25 GAP84598.1 - 3.5e-36 124.9 0.0 1.9e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84598.1 - 2.7e-17 62.9 0.0 2e-16 60.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase 4HBT_2 PF13279.6 GAP84599.1 - 0.00014 22.3 0.0 0.00021 21.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily CFEM PF05730.11 GAP84600.1 - 7.2e-10 38.8 12.9 1.3e-09 38.0 12.9 1.4 1 0 0 1 1 1 1 CFEM domain DUF3435 PF11917.8 GAP84601.1 - 2.6e-11 43.1 0.6 1.4e-05 24.2 0.0 2.0 1 1 0 2 2 2 2 Protein of unknown function (DUF3435) CN_hydrolase PF00795.22 GAP84602.1 - 1.8e-38 132.4 0.0 2.7e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 GAP84602.1 - 1.1e-23 83.6 0.0 3.5e-23 82.0 0.0 1.7 1 1 0 1 1 1 1 NAD synthase PCRF PF03462.18 GAP84603.1 - 5.1e-46 157.0 0.3 1.2e-45 155.8 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 GAP84603.1 - 2.1e-33 114.7 1.5 5.2e-33 113.4 1.5 1.7 1 0 0 1 1 1 1 RF-1 domain CorA PF01544.18 GAP84603.1 - 0.13 11.5 0.9 0.23 10.8 0.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Peptidase_S10 PF00450.22 GAP84604.1 - 1.2e-81 275.3 0.0 1.6e-81 274.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.25 GAP84605.1 - 5e-73 245.7 0.0 1.2e-72 244.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84605.1 - 9e-49 166.1 0.0 1.7e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP84605.1 - 7.8e-05 21.6 0.0 0.00017 20.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 GAP84605.1 - 0.0048 16.2 0.0 0.053 12.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF3384 PF11864.8 GAP84605.1 - 0.1 11.5 5.3 2.9 6.7 5.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3384) GerD PF17898.1 GAP84605.1 - 0.35 10.8 1.3 1.1 9.2 1.3 1.8 1 0 0 1 1 1 0 Spore germination GerD central core domain adh_short_C2 PF13561.6 GAP84606.1 - 2.6e-40 138.4 1.1 5.4e-40 137.4 1.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP84606.1 - 1e-35 123.0 0.6 1.6e-35 122.3 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP84606.1 - 8.3e-05 22.6 1.0 0.00019 21.4 1.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP84606.1 - 0.00054 19.5 0.3 0.05 13.0 0.2 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP84606.1 - 0.00098 19.1 0.2 0.0015 18.4 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 GAP84606.1 - 0.0033 17.7 0.2 0.0053 17.0 0.2 1.3 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N PF00107.26 GAP84606.1 - 0.0044 17.0 1.6 0.0083 16.1 1.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.27 GAP84606.1 - 0.012 16.1 0.4 0.024 15.2 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 GAP84606.1 - 0.012 15.8 0.4 0.018 15.3 0.4 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 GAP84606.1 - 0.018 14.7 0.4 0.029 14.0 0.4 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA B12-binding PF02310.19 GAP84606.1 - 0.083 12.9 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 B12 binding domain 3HCDH_N PF02737.18 GAP84606.1 - 0.13 12.2 1.5 0.2 11.5 1.5 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rad52_Rad22 PF04098.15 GAP84608.1 - 1.4e-60 203.6 0.0 2e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Cut8 PF08559.10 GAP84609.1 - 6.9e-76 255.0 0.0 8.3e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Lyase_aromatic PF00221.19 GAP84611.1 - 1.8e-151 505.0 3.8 2.1e-151 504.7 3.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase adh_short PF00106.25 GAP84612.1 - 5.3e-40 137.0 0.1 7.6e-40 136.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84612.1 - 1.9e-29 102.9 0.1 2.4e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP84612.1 - 4.6e-12 46.2 0.0 6.9e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP84612.1 - 0.00014 21.4 0.1 0.00027 20.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAP84612.1 - 0.002 17.3 0.0 0.0027 16.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 GAP84612.1 - 0.0054 16.1 0.0 0.0075 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 GAP84612.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAP84612.1 - 0.032 13.8 0.0 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 GAP84612.1 - 0.06 12.4 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 GAP84613.1 - 2e-24 86.1 0.2 2.7e-24 85.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84613.1 - 3.2e-13 49.8 0.1 4.7e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAP84613.1 - 3.8e-05 23.3 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 GAP84613.1 - 9.7e-05 22.3 0.2 0.00024 21.1 0.1 1.6 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 GAP84613.1 - 0.012 15.0 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAP84613.1 - 0.11 12.4 0.4 0.2 11.5 0.4 1.7 1 1 0 1 1 1 0 NAD(P)H-binding FAD_binding_4 PF01565.23 GAP84614.1 - 5.5e-22 78.0 0.4 9.7e-22 77.2 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP84614.1 - 0.0011 19.1 0.7 0.0044 17.1 0.7 2.1 1 1 0 1 1 1 1 Berberine and berberine like FAD_binding_3 PF01494.19 GAP84615.1 - 2.5e-20 73.0 0.0 3.9e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP84615.1 - 1e-07 31.9 0.6 7e-05 22.6 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP84615.1 - 3.2e-06 27.3 0.5 7.9e-06 26.0 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP84615.1 - 4.8e-06 26.0 0.1 8.3e-05 22.0 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP84615.1 - 1.1e-05 25.9 0.0 0.0004 20.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP84615.1 - 5.7e-05 22.0 0.1 0.011 14.4 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 GAP84615.1 - 7.8e-05 21.9 0.8 0.00013 21.2 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 GAP84615.1 - 0.0001 21.7 0.7 0.0051 16.1 0.8 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 GAP84615.1 - 0.0028 17.0 0.0 0.033 13.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP84615.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 GAP84615.1 - 0.015 14.4 0.3 0.022 13.9 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 GAP84615.1 - 0.023 14.4 0.2 0.042 13.5 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 GAP84615.1 - 0.078 12.3 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAP84615.1 - 0.11 11.8 0.1 0.21 10.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 GAP84615.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cupin_2 PF07883.11 GAP84616.1 - 4.5e-08 32.7 0.0 8.5e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain p450 PF00067.22 GAP84617.1 - 5e-61 206.9 0.0 5.7e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 GAP84618.1 - 5.2e-34 117.7 13.6 7.2e-34 117.2 13.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family NPP1 PF05630.11 GAP84621.1 - 6.9e-66 222.1 0.0 8e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) HET PF06985.11 GAP84622.1 - 4.3e-25 88.8 1.0 1.4e-24 87.1 1.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tubulin PF00091.25 GAP84623.1 - 2.4e-69 233.5 0.0 3.4e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAP84623.1 - 2e-45 154.0 0.3 5.5e-45 152.6 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAP84623.1 - 1.1e-07 32.2 0.0 2.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 GAP84623.1 - 0.066 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Tubulin domain Hrs_helical PF12210.8 GAP84623.1 - 0.22 12.1 0.4 0.85 10.2 0.0 2.2 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate WD40 PF00400.32 GAP84625.1 - 8.2e-19 67.6 10.9 0.0013 19.5 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP84625.1 - 8.5e-09 35.6 0.0 4.3e-05 23.7 0.0 4.5 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAP84625.1 - 7.6e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 GAP84625.1 - 0.0024 16.9 0.3 0.074 12.0 0.0 2.9 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAP84625.1 - 0.047 12.3 0.3 0.28 9.8 0.3 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Peptidase_M24 PF00557.24 GAP84626.1 - 2.4e-39 135.2 0.0 3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 CCDC106 PF15794.5 GAP84626.1 - 1 9.0 3.7 1.6 8.4 3.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TSGP1 PF07771.11 GAP84626.1 - 3.8 7.7 9.4 8.1 6.6 9.4 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 Goodbye PF17109.5 GAP84627.1 - 3e-18 66.4 0.0 8.1e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 GAP84627.1 - 0.00013 22.0 0.0 0.00053 20.0 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAP84627.1 - 0.0054 17.0 0.0 0.024 14.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain TPR_2 PF07719.17 GAP84627.1 - 0.049 13.8 3.0 33 4.9 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_helicase PF00910.22 GAP84627.1 - 0.075 13.4 0.0 0.37 11.2 0.0 2.3 1 0 0 1 1 1 0 RNA helicase TPR_8 PF13181.6 GAP84627.1 - 0.099 12.9 0.1 24 5.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 GAP84627.1 - 0.12 13.1 5.4 0.27 12.0 0.0 4.1 5 0 0 5 5 5 0 Sel1 repeat AAA_16 PF13191.6 GAP84627.1 - 0.17 12.2 0.3 5 7.5 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain C1_2 PF03107.16 GAP84627.1 - 2.3 8.6 4.7 5 7.5 4.7 1.5 1 0 0 1 1 1 0 C1 domain C2 PF00168.30 GAP84628.1 - 3e-14 53.1 0.0 5.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF3987 PF13148.6 GAP84629.1 - 0.38 9.7 2.3 0.67 8.9 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF1053 PF06327.14 GAP84629.1 - 2 9.0 5.3 0.99 10.0 1.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) TMEM234 PF10639.9 GAP84630.1 - 8.2e-35 119.3 0.2 1.2e-34 118.9 0.2 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 GAP84630.1 - 7.4e-06 26.2 1.9 0.0063 16.7 1.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family UPF0060 PF02694.15 GAP84630.1 - 1.8 8.9 6.6 0.24 11.6 2.8 1.7 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family CH PF00307.31 GAP84632.1 - 1.9e-69 230.8 0.0 3e-18 66.0 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 GAP84632.1 - 0.00047 20.5 0.5 0.0081 16.6 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GAP84632.1 - 0.092 12.3 1.4 52 3.7 0.4 3.7 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 GAP84632.1 - 0.81 9.8 3.7 5.4 7.2 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain MBOAT PF03062.19 GAP84633.1 - 2.4e-39 135.7 14.9 2.4e-39 135.7 14.9 2.4 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 GAP84633.1 - 5e-05 23.5 2.0 0.00016 21.9 2.0 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RRM_1 PF00076.22 GAP84634.1 - 1.1e-11 44.4 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAP84634.1 - 4.2e-05 23.5 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 GAP84635.1 - 1.7e-73 242.7 4.3 2.7e-24 84.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAP84635.1 - 7.5e-05 22.0 0.9 0.0042 16.3 0.0 3.1 3 1 1 4 4 4 2 Gammaproteobacterial serine protease Ribosomal_L18 PF17135.4 GAP84636.1 - 1.6e-94 314.6 2.6 1.7e-94 314.5 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 GAP84636.1 - 0.00057 20.6 0.0 0.0014 19.3 0.0 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SRAP PF02586.14 GAP84637.1 - 1.2e-83 279.9 0.0 1.7e-83 279.5 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Amidase_6 PF12671.7 GAP84637.1 - 0.0051 16.9 0.7 0.0096 16.0 0.4 1.6 1 1 0 1 1 1 1 Putative amidase domain Shadoo PF14999.6 GAP84638.1 - 0.005 16.9 2.2 0.0061 16.7 2.2 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective DUF1616 PF07760.11 GAP84638.1 - 0.088 12.2 0.4 0.1 11.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) LOR PF04525.12 GAP84639.1 - 7.2e-07 29.0 0.6 1.1e-06 28.3 0.6 1.3 1 1 0 1 1 1 1 LURP-one-related Methyltransf_33 PF10017.9 GAP84639.1 - 0.12 11.5 0.3 0.16 11.1 0.3 1.1 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent MBOAT_2 PF13813.6 GAP84640.1 - 1.6e-16 60.3 2.4 1.6e-16 60.3 2.4 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family TMEM208_SND2 PF05620.11 GAP84640.1 - 0.83 9.4 9.4 0.64 9.8 0.1 3.5 3 1 1 4 4 4 0 SRP-independent targeting protein 2/TMEM208 Cellulase PF00150.18 GAP84641.1 - 1.8e-50 172.0 0.0 2.1e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_61 PF03443.14 GAP84642.1 - 1.5e-43 149.2 0.0 1.8e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CDH-cyt PF16010.5 GAP84643.1 - 1.8e-60 203.8 1.1 3.1e-60 203.0 0.3 1.9 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 GAP84643.1 - 5.7e-26 91.6 0.0 1.5e-25 90.2 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP84643.1 - 1.3e-22 80.9 0.0 2.2e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAP84643.1 - 2.2e-06 27.0 0.0 0.0024 17.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAP84643.1 - 7.9e-05 22.8 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP84643.1 - 0.00021 20.6 0.0 0.003 16.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAP84643.1 - 0.00066 18.8 0.1 0.0015 17.7 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 GAP84643.1 - 0.00081 19.1 0.2 0.02 14.5 0.1 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase DOMON PF03351.17 GAP84643.1 - 0.0023 18.2 0.0 0.014 15.6 0.0 2.3 2 0 0 2 2 2 1 DOMON domain Pyr_redox_3 PF13738.6 GAP84643.1 - 0.003 16.8 0.3 0.0076 15.5 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP84643.1 - 0.0051 15.6 0.0 0.0073 15.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 GAP84643.1 - 0.041 13.1 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Zn_clus PF00172.18 GAP84644.1 - 3.7e-07 30.1 7.0 7.1e-07 29.3 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP84644.1 - 0.0032 16.5 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NifW PF03206.14 GAP84646.1 - 0.013 16.0 0.1 0.034 14.7 0.1 1.6 1 0 0 1 1 1 0 Nitrogen fixation protein NifW 6PF2K PF01591.18 GAP84647.1 - 3e-66 222.9 0.0 4e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAP84647.1 - 2.9e-20 72.8 0.0 6.5e-20 71.6 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAP84647.1 - 4.8e-06 26.8 0.1 1.1e-05 25.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAP84647.1 - 0.0017 17.9 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 GAP84647.1 - 0.023 15.2 0.0 0.08 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 GAP84647.1 - 0.037 14.1 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Torsin Zeta_toxin PF06414.12 GAP84647.1 - 0.059 12.6 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 GAP84647.1 - 0.074 12.7 0.1 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 GAP84647.1 - 0.09 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAP84647.1 - 0.097 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.13 GAP84648.1 - 1.6e-55 188.3 0.1 2.1e-55 187.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAP84648.1 - 4.2e-10 39.1 0.0 1.2e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 GAP84648.1 - 0.0014 18.2 0.0 0.24 10.9 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 GAP84648.1 - 0.0019 17.8 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase_phd PF10503.9 GAP84648.1 - 0.0024 17.4 0.2 0.0024 17.4 0.2 2.4 2 1 0 2 2 2 1 Esterase PHB depolymerase AXE1 PF05448.12 GAP84648.1 - 0.064 11.9 0.2 0.32 9.6 0.1 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) IDO PF01231.18 GAP84649.1 - 1.8e-35 122.6 0.0 2.4e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase INO80_Ies4 PF08193.11 GAP84650.1 - 5.8e-58 196.7 19.6 6.4e-58 196.6 19.6 1.0 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.9 GAP84651.1 - 1.8e-34 118.8 0.1 7.8e-34 116.7 0.1 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 GAP84651.1 - 8.1e-28 97.0 0.1 1.3e-27 96.2 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 GAP84651.1 - 6e-05 22.8 1.4 0.00012 21.9 0.1 2.3 3 0 0 3 3 3 1 LisH Adeno_PV PF03910.13 GAP84652.1 - 0.87 8.2 6.1 0.93 8.1 6.1 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF4148 PF13663.6 GAP84652.1 - 1.6 8.9 10.1 2.9 8.2 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) GST_N_4 PF17172.4 GAP84653.1 - 8e-20 71.4 0.0 1.4e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GAP84653.1 - 1e-15 57.3 0.0 2.2e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 GAP84653.1 - 1.2e-08 35.3 0.2 4.7e-08 33.4 0.2 2.0 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C PF00043.25 GAP84653.1 - 0.012 15.9 0.0 0.032 14.4 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 GAP84653.1 - 0.029 14.6 0.1 0.058 13.7 0.1 1.5 1 0 0 1 1 1 0 SAM35, subunit of SAM coomplex adh_short_C2 PF13561.6 GAP84654.1 - 1.3e-38 132.9 0.3 4.1e-32 111.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP84654.1 - 1.6e-26 93.0 0.0 6e-24 84.6 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase DUF4238 PF14022.6 GAP84655.1 - 2.4e-70 237.2 2.1 3.4e-70 236.7 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Egh16-like PF11327.8 GAP84656.1 - 1.3e-24 87.6 7.7 2.7e-24 86.6 7.7 1.5 1 0 0 1 1 1 1 Egh16-like virulence factor TPMT PF05724.11 GAP84657.1 - 1.9e-33 115.9 0.0 3.2e-28 98.9 0.0 2.1 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 GAP84657.1 - 1.7e-11 44.7 0.0 2.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP84657.1 - 2.4e-09 37.7 0.0 3.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP84657.1 - 6.7e-08 32.5 0.0 1.3e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP84657.1 - 7.6e-08 32.3 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP84657.1 - 2.1e-07 31.6 0.0 4.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 GAP84657.1 - 0.091 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB N2227 PF07942.12 GAP84657.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein Aldedh PF00171.22 GAP84658.1 - 5.9e-13 48.1 10.5 2.6e-07 29.5 7.3 2.7 1 1 1 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 GAP84658.1 - 0.0042 16.3 0.0 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF885 PF05960.11 GAP84658.1 - 2.2 7.8 5.7 25 4.3 5.7 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Peptidase_M14 PF00246.24 GAP84659.1 - 1e-14 55.0 0.0 2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 GAP84659.1 - 0.00024 20.3 0.0 0.00043 19.4 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 GAP84659.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) MFS_1 PF07690.16 GAP84661.1 - 1.9e-39 135.6 64.0 8.9e-39 133.4 39.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily RseC_MucC PF04246.12 GAP84661.1 - 0.71 9.8 4.0 2.1 8.3 0.3 2.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PALP PF00291.25 GAP84662.1 - 1.5e-63 215.0 0.8 2.3e-63 214.4 0.8 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Transglut_core PF01841.19 GAP84662.1 - 0.14 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily IlvN PF07991.12 GAP84663.1 - 2.8e-46 157.1 0.0 4.3e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 GAP84663.1 - 2.3e-41 141.4 0.1 5.5e-41 140.2 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 GAP84663.1 - 0.037 14.6 0.0 0.12 13.0 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAP84663.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UQ_con PF00179.26 GAP84664.1 - 1.8e-37 128.1 0.0 2.5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 GAP84664.1 - 0.059 13.7 0.1 0.097 13.0 0.1 1.3 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 GAP84664.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 GAP84664.1 - 0.13 11.9 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Mcp5_PH PF12814.7 GAP84665.1 - 5.4e-46 155.7 0.0 1.5e-45 154.3 0.0 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 GAP84665.1 - 0.0039 17.7 13.8 0.0086 16.6 13.8 1.5 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 GAP84665.1 - 0.87 8.4 13.1 1.5 7.7 13.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 GAP84665.1 - 2.3 7.5 16.6 3 7.1 15.5 1.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 GAP84665.1 - 3.3 7.8 23.5 0.26 11.4 13.0 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 GAP84665.1 - 6.9 6.0 16.5 12 5.2 16.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Ras PF00071.22 GAP84666.1 - 2.3e-51 173.6 0.0 3.9e-51 172.9 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAP84666.1 - 1e-17 64.5 0.0 2.2e-16 60.2 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP84666.1 - 0.00039 19.9 0.0 0.0014 18.1 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAP84666.1 - 0.0071 16.3 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAP84666.1 - 0.046 13.3 0.1 0.45 10.0 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B Abhydrolase_4 PF08386.10 GAP84666.1 - 0.049 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein AAA_16 PF13191.6 GAP84666.1 - 0.079 13.3 0.1 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 GAP84666.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.6 GAP84667.1 - 1.1e-08 35.3 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP84667.1 - 4.4e-08 33.7 0.0 7.1e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP84667.1 - 7.6e-05 22.7 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Opy2 PF09463.10 GAP84668.1 - 8.5e-09 35.6 20.3 1.3e-08 35.0 20.3 1.3 1 0 0 1 1 1 1 Opy2 protein DUF2076 PF09849.9 GAP84668.1 - 0.19 11.7 0.5 2.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Chitin_synth_1 PF01644.17 GAP84669.1 - 1.4e-69 233.2 0.0 2.3e-69 232.5 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAP84669.1 - 6.2e-27 93.3 0.0 1.2e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAP84669.1 - 2.3e-24 85.9 0.0 1.9e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase OTU PF02338.19 GAP84669.1 - 6.3e-22 78.4 0.0 1.5e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Glyco_trans_2_3 PF13632.6 GAP84669.1 - 3.7e-08 33.5 0.9 1.5e-07 31.5 0.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Peptidase_C65 PF10275.9 GAP84669.1 - 0.0016 17.9 0.0 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 Peptidase C65 Otubain DUF3989 PF13150.6 GAP84669.1 - 0.23 11.2 7.3 12 5.7 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3989) CAP-ZIP_m PF15255.6 GAP84669.1 - 0.4 11.0 4.3 0.87 9.9 4.3 1.5 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region DHHC PF01529.20 GAP84669.1 - 9.7 6.3 14.4 6.6 6.8 2.9 3.4 2 1 1 3 3 3 0 DHHC palmitoyltransferase OPT PF03169.15 GAP84670.1 - 2.9e-130 435.8 45.3 3.3e-130 435.6 45.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein APH PF01636.23 GAP84671.1 - 1.5e-08 34.8 0.0 1.8e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP84671.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 GAP84671.1 - 0.25 10.6 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3405 PF11885.8 GAP84672.1 - 1.8e-183 610.8 0.4 2.7e-183 610.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) LIM PF00412.22 GAP84673.1 - 9.1e-24 83.5 16.2 9.7e-13 48.1 5.5 2.9 3 0 0 3 3 3 2 LIM domain WRC PF08879.10 GAP84673.1 - 0.037 13.7 1.3 0.38 10.5 0.6 2.3 2 0 0 2 2 2 0 WRC zf-C2H2 PF00096.26 GAP84673.1 - 2.2 8.9 4.6 36 5.1 0.4 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf_C2HC_14 PF18574.1 GAP84673.1 - 2.5 7.9 6.1 1.8 8.4 1.1 2.6 2 0 0 2 2 2 0 C2HC Zing finger domain Desulfoferrod_N PF06397.12 GAP84673.1 - 2.7 7.7 4.9 1.2 8.8 0.3 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain NAD_binding_5 PF07994.12 GAP84674.1 - 8.8e-144 478.8 0.0 1.2e-143 478.4 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 GAP84674.1 - 1.6e-45 153.8 0.7 4e-45 152.5 0.7 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Aldo_ket_red PF00248.21 GAP84676.1 - 2e-42 145.4 0.0 2.9e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Ribonuc_L-PSP PF01042.21 GAP84676.1 - 1.6e-12 47.5 0.0 5.7e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Endoribonuclease L-PSP PIF1 PF05970.14 GAP84677.1 - 7.6e-38 130.6 0.0 2e-27 96.3 0.0 2.5 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 GAP84677.1 - 3.9e-22 78.9 0.0 4.2e-20 72.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAP84677.1 - 9.8e-09 35.7 0.0 2.6e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 GAP84677.1 - 1.7e-06 28.1 0.0 0.037 13.9 0.0 2.7 3 0 0 3 3 3 2 NTPase Herpes_Helicase PF02689.14 GAP84677.1 - 1.7e-06 26.3 0.0 6.1e-05 21.2 0.0 2.3 3 0 0 3 3 3 1 Helicase Viral_helicase1 PF01443.18 GAP84677.1 - 7e-06 25.9 1.0 0.13 12.0 0.1 3.6 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 GAP84677.1 - 2.8e-05 24.4 0.0 8.2e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 GAP84677.1 - 6.5e-05 22.0 0.1 0.00011 21.4 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB UvrD_C_2 PF13538.6 GAP84677.1 - 0.00014 21.6 0.0 0.00054 19.7 0.0 2.1 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 GAP84677.1 - 0.0033 17.4 0.0 0.022 14.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAP84677.1 - 0.0041 16.3 0.0 0.0085 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 GAP84677.1 - 0.0042 17.5 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 GAP84677.1 - 0.0043 17.1 0.0 0.024 14.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 GAP84677.1 - 0.0062 16.3 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA PF00004.29 GAP84677.1 - 0.0089 16.5 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 GAP84677.1 - 0.012 16.1 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter PRK PF00485.18 GAP84677.1 - 0.051 13.3 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 GAP84677.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 GAP84677.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 GAP84677.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_7 PF12775.7 GAP84677.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 GAP84677.1 - 0.15 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TniB PF05621.11 GAP84677.1 - 0.17 11.3 0.0 0.42 10.0 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein DUF1996 PF09362.10 GAP84678.1 - 1.8e-82 276.9 0.3 2.2e-82 276.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AMP-binding PF00501.28 GAP84679.1 - 5.5e-83 278.9 0.0 6.8e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP84679.1 - 1.6e-12 48.2 0.3 3.6e-12 47.1 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.14 GAP84680.1 - 1.2e-17 64.1 0.1 5.7e-12 45.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP84680.1 - 0.00089 18.4 0.5 0.011 14.8 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 GAP84680.1 - 0.0018 17.1 0.1 0.003 16.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 GAP84680.1 - 0.0023 18.1 0.1 0.005 17.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAP84680.1 - 0.012 14.8 0.4 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 GAP84680.1 - 0.013 14.6 0.1 0.03 13.4 0.0 1.6 1 1 1 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 GAP84680.1 - 0.014 14.6 0.3 0.033 13.4 0.2 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 GAP84680.1 - 0.026 13.8 0.1 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAP84680.1 - 0.046 12.8 0.1 0.089 11.8 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein T3SS_ExsE PF18286.1 GAP84680.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Type III secretion system ExsE FAD_oxidored PF12831.7 GAP84680.1 - 0.23 10.7 1.6 0.34 10.2 1.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 GAP84680.1 - 0.5 9.9 4.8 0.34 10.4 1.4 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Cyt-b5 PF00173.28 GAP84681.1 - 2e-14 53.5 0.0 7.2e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 GAP84681.1 - 6.9e-13 48.2 0.0 5.6e-12 45.2 0.0 2.1 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.20 GAP84681.1 - 2.1e-08 34.1 0.0 4.8e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 GAP84681.1 - 6.4e-08 33.2 0.0 1.8e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Lipase_GDSL_2 PF13472.6 GAP84682.1 - 1.3e-10 41.9 0.6 1.8e-10 41.5 0.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP84682.1 - 0.0024 17.9 0.5 0.0052 16.8 0.5 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DPBB_1 PF03330.18 GAP84683.1 - 3.5e-05 24.0 0.2 5.6e-05 23.3 0.2 1.4 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAP84683.1 - 0.033 14.0 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 Barwin family RSN1_7TM PF02714.15 GAP84684.1 - 1.7e-75 253.9 19.5 2.6e-75 253.3 19.5 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAP84684.1 - 1.6e-38 132.7 0.2 2.3e-38 132.2 0.2 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GAP84684.1 - 7.6e-36 123.2 2.1 7.6e-36 123.2 2.1 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4361 PF14274.6 GAP84684.1 - 0.11 12.8 0.9 0.17 12.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4361) DUF4407 PF14362.6 GAP84684.1 - 0.41 10.0 1.0 9.7 5.4 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) A_deaminase PF00962.22 GAP84686.1 - 4e-24 85.6 0.0 7.6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase GATase_4 PF13230.6 GAP84686.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II NAD_binding_10 PF13460.6 GAP84687.1 - 2.3e-07 30.9 0.0 1.4e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAP84687.1 - 4.9e-06 26.3 0.0 1.4e-05 24.8 0.0 1.7 2 1 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 GAP84687.1 - 0.0009 19.5 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 GAP84687.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 GAP84687.1 - 0.077 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding LpxI_N PF17930.1 GAP84687.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain CsbD PF05532.12 GAP84688.1 - 7.2e-19 67.4 20.1 4.8e-10 39.2 2.6 3.4 2 1 1 3 3 3 3 CsbD-like Aminotran_5 PF00266.19 GAP84689.1 - 4.6e-92 308.8 0.0 5.5e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAP84689.1 - 1.9e-06 27.4 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAP84689.1 - 4.3e-05 23.0 0.0 9.1e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 GAP84689.1 - 0.00025 19.9 0.0 0.0004 19.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 GAP84689.1 - 0.014 13.9 0.0 0.021 13.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BAR PF03114.18 GAP84690.1 - 3.5e-66 223.3 6.5 4.4e-66 222.9 6.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 GAP84690.1 - 1e-14 53.9 0.0 1.8e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAP84690.1 - 9.5e-12 44.6 0.0 1.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAP84690.1 - 1.9e-09 37.0 0.1 4.4e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Condensation PF00668.20 GAP84691.1 - 1.9e-144 481.8 0.0 2.2e-84 283.7 0.0 3.4 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 GAP84691.1 - 7.7e-141 469.5 0.0 2.9e-75 253.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 GAP84691.1 - 2.9e-33 114.0 0.1 1.5e-10 41.3 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site ApbA_C PF08546.11 GAP84691.1 - 1.7e-30 105.8 0.0 4.7e-30 104.4 0.0 1.8 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 GAP84691.1 - 1.1e-25 90.0 0.0 2.5e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AMP-binding_C PF13193.6 GAP84691.1 - 2.2e-05 25.3 0.0 0.44 11.6 0.0 4.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.6 GAP84691.1 - 7.4e-05 23.4 0.0 0.0003 21.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP84691.1 - 0.00021 21.2 0.0 0.0007 19.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP84691.1 - 0.00024 21.7 0.0 0.00079 20.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP84691.1 - 0.0041 17.8 0.0 0.013 16.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PMI_typeI PF01238.21 GAP84692.1 - 3.5e-120 401.6 0.0 4.1e-120 401.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 GAP84692.1 - 0.01 15.7 0.0 7.1 6.5 0.0 2.6 2 0 0 2 2 2 0 AraC-like ligand binding domain PHY PF00360.20 GAP84692.1 - 0.19 11.0 0.0 7.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Phytochrome region F-box-like PF12937.7 GAP84695.1 - 1.4e-06 28.1 0.3 4.6e-06 26.4 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAP84695.1 - 0.016 15.0 1.1 2.9 7.9 0.1 2.8 3 0 0 3 3 3 0 F-box domain Meth_synt_2 PF01717.18 GAP84696.1 - 4e-12 46.0 0.0 3.5e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 GAP84696.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain 5_nucleotid_C PF02872.18 GAP84697.1 - 1.6e-37 129.2 0.0 3.2e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 GAP84697.1 - 7.9e-06 26.5 0.1 1.2e-05 25.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EamA PF00892.20 GAP84698.1 - 2.6e-08 34.1 34.1 6e-06 26.5 4.4 2.8 2 1 1 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 GAP84698.1 - 8.5e-06 25.0 15.0 0.00059 18.9 14.5 2.7 1 1 0 1 1 1 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 GAP84698.1 - 0.0085 15.3 0.2 0.0085 15.3 0.2 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter CDC45 PF02724.14 GAP84698.1 - 0.013 13.9 0.1 0.017 13.4 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC35F PF06027.12 GAP84698.1 - 0.12 11.9 5.9 0.2 11.1 6.0 1.5 1 1 0 1 1 1 0 Solute carrier family 35 Aldo_ket_red PF00248.21 GAP84699.1 - 1.1e-46 159.4 0.0 1.2e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MMR_HSR1 PF01926.23 GAP84700.1 - 1.4e-06 28.4 0.6 4.6e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAP84700.1 - 1.4e-05 24.5 0.0 3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family DUF3040 PF11239.8 GAP84700.1 - 0.0035 17.6 0.8 0.021 15.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3040) RsgA_GTPase PF03193.16 GAP84700.1 - 0.0071 16.3 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 GAP84700.1 - 0.0099 16.0 9.3 0.81 9.7 0.3 3.9 4 1 1 5 5 5 2 Dynamin family IIGP PF05049.13 GAP84700.1 - 0.018 14.1 0.5 0.055 12.5 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.27 GAP84700.1 - 0.049 13.2 1.7 33 3.9 0.0 3.9 3 2 0 3 3 3 0 Elongation factor Tu GTP binding domain Viral_helicase1 PF01443.18 GAP84700.1 - 0.055 13.2 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 GAP84700.1 - 0.099 12.7 0.0 0.099 12.7 0.0 2.9 2 1 0 2 2 1 0 Helicase HerA, central domain ABC_tran PF00005.27 GAP84700.1 - 0.12 12.9 2.3 0.32 11.5 0.0 2.6 2 1 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 GAP84700.1 - 0.24 11.2 0.7 1.6 8.4 0.0 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Septin PF00735.18 GAP84700.1 - 0.5 9.6 0.0 0.5 9.6 0.0 2.5 3 0 0 3 3 3 0 Septin AAA_16 PF13191.6 GAP84700.1 - 0.79 10.1 3.5 1.5 9.2 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 GAP84700.1 - 2.7 8.3 0.0 2.7 8.3 0.0 2.9 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 GAP84701.1 - 8.7e-10 38.7 1.5 2.3e-09 37.4 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAP84701.1 - 2.2e-05 23.9 2.0 0.00063 19.1 0.0 2.4 2 0 0 2 2 2 1 AIG1 family Septin PF00735.18 GAP84701.1 - 9.8e-05 21.8 0.5 0.00019 20.8 0.0 1.7 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 GAP84701.1 - 0.0031 17.4 0.0 0.014 15.3 0.0 2.0 1 1 0 1 1 1 1 RsgA GTPase IIGP PF05049.13 GAP84701.1 - 0.008 15.3 0.7 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 GAP84701.1 - 0.027 14.5 11.2 0.17 11.9 0.0 3.7 2 2 2 4 4 4 0 Dynamin family AAA_18 PF13238.6 GAP84701.1 - 0.067 13.7 0.7 0.37 11.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAP84701.1 - 0.068 13.4 3.3 0.09 13.1 0.0 2.5 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 GAP84701.1 - 0.078 13.5 0.8 0.67 10.5 0.0 2.5 2 1 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 GAP84701.1 - 0.18 11.5 0.1 0.18 11.5 0.1 2.8 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 GAP84701.1 - 0.18 10.7 1.3 0.43 9.5 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 GAP84701.1 - 0.3 10.8 1.4 0.37 10.5 0.1 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 GAP84701.1 - 0.39 10.4 2.1 2.4 7.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 GAP84701.1 - 0.9 9.1 3.7 0.82 9.3 0.5 2.4 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain Fib_alpha PF08702.10 GAP84701.1 - 1 9.6 9.3 0.28 11.3 1.0 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 GAP84701.1 - 1.5 9.2 14.1 3.2 8.1 14.1 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 GAP84701.1 - 1.5 7.4 10.3 2.7 6.5 10.3 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Fungal_TACC PF12709.7 GAP84701.1 - 2.1 8.9 8.1 1.1 9.7 0.7 3.0 3 0 0 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins CENP-H PF05837.12 GAP84701.1 - 2.8 8.4 13.8 16 6.0 13.5 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF87 PF01935.17 GAP84701.1 - 5.4 7.0 12.5 0.72 9.9 0.3 2.9 2 1 0 2 2 2 0 Helicase HerA, central domain DUF1664 PF07889.12 GAP84701.1 - 7.6 6.6 8.2 3.6 7.6 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HGTP_anticodon PF03129.20 GAP84702.1 - 1.1e-19 70.3 0.0 1.2e-18 67.1 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAP84702.1 - 5.2e-09 36.3 0.1 4e-08 33.4 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Ank_2 PF12796.7 GAP84703.1 - 2.6e-10 40.8 0.1 4.5e-05 24.0 0.3 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAP84703.1 - 2.2e-09 37.3 0.2 0.00032 21.0 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 GAP84703.1 - 3.7e-08 33.0 0.0 0.021 15.3 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 GAP84703.1 - 8.3e-08 32.6 0.6 0.0098 16.5 0.3 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP84703.1 - 1.7e-06 28.2 0.2 0.00034 20.8 0.2 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.13 GAP84703.1 - 2.3e-05 24.2 0.2 0.00018 21.3 0.2 2.4 1 1 0 1 1 1 1 KilA-N domain AAA_13 PF13166.6 GAP84703.1 - 0.0047 15.6 3.9 0.0047 15.6 3.9 2.1 3 0 0 3 3 3 1 AAA domain PMEI PF04043.15 GAP84703.1 - 1.7 9.0 4.0 2.2 8.6 2.2 2.1 2 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor APG6_N PF17675.1 GAP84703.1 - 2.1 8.9 14.0 7.6 7.1 9.6 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Endonuclease_NS PF01223.23 GAP84705.1 - 0.0048 16.7 0.3 0.011 15.5 0.3 1.5 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease TraG_N PF07916.11 GAP84705.1 - 0.16 10.8 8.0 0.25 10.1 8.0 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region adh_short PF00106.25 GAP84706.1 - 9e-34 116.6 0.0 1.2e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84706.1 - 1.1e-16 61.1 1.0 1.6e-16 60.6 1.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP84706.1 - 2.5e-09 37.3 1.6 1.4e-07 31.6 1.6 2.3 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 GAP84706.1 - 0.068 13.4 0.4 0.12 12.6 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Asp PF00026.23 GAP84707.1 - 6.4e-74 249.2 1.2 7.4e-74 249.0 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP84707.1 - 1.1e-12 48.6 1.2 7.9e-07 29.5 0.0 2.8 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAP84707.1 - 0.0005 20.6 2.2 0.11 13.2 0.6 2.7 2 1 0 2 2 2 2 Aspartyl protease Voltage_CLC PF00654.20 GAP84708.1 - 5.2e-91 305.5 26.0 5.2e-91 305.5 26.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 GAP84708.1 - 1.2e-12 48.1 0.8 1.8e-05 25.1 0.0 3.0 2 1 1 3 3 3 2 CBS domain CBFD_NFYB_HMF PF00808.23 GAP84709.1 - 7.4e-11 42.2 0.0 2.2e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LIP1 PF15904.5 GAP84709.1 - 0.13 12.6 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 LRR_9 PF14580.6 GAP84710.1 - 4.4e-53 179.3 0.2 7e-53 178.7 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 GAP84710.1 - 2e-06 27.4 2.9 2e-06 27.4 2.9 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 GAP84710.1 - 3e-06 27.5 10.3 0.00036 20.9 4.1 3.4 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) DUF4349 PF14257.6 GAP84710.1 - 0.12 11.8 4.9 0.095 12.1 3.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) PspB PF06667.12 GAP84710.1 - 0.17 12.0 1.6 0.49 10.5 1.6 1.8 1 0 0 1 1 1 0 Phage shock protein B LRR_6 PF13516.6 GAP84710.1 - 0.53 10.5 4.8 55 4.2 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Aldo_ket_red PF00248.21 GAP84712.1 - 8.9e-64 215.5 0.0 1e-63 215.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 GAP84713.1 - 4.6e-09 36.3 7.9 4.6e-09 36.3 7.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactonase PF10282.9 GAP84714.1 - 1e-84 284.8 0.0 1e-84 284.8 0.0 1.4 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller DUF2722 PF10846.8 GAP84714.1 - 0.0016 17.5 0.1 0.0017 17.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) CcmD PF04995.14 GAP84714.1 - 0.026 14.6 3.0 0.091 12.9 3.0 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4407 PF14362.6 GAP84714.1 - 0.052 12.9 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliP PF00813.20 GAP84714.1 - 0.28 11.0 0.8 0.45 10.4 0.2 1.5 2 0 0 2 2 2 0 FliP family Activator_LAG-3 PF11498.8 GAP84714.1 - 1.2 8.0 13.0 1.7 7.5 13.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 GAP84714.1 - 1.4 8.5 13.3 2.1 7.9 13.3 1.1 1 0 0 1 1 1 0 Spt20 family DivIC PF04977.15 GAP84714.1 - 2.4 8.0 6.9 3.8 7.3 6.9 1.3 1 0 0 1 1 1 0 Septum formation initiator Ly49 PF08391.10 GAP84714.1 - 3.4 8.1 5.6 5.7 7.3 5.6 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region WD40 PF00400.32 GAP84716.1 - 1.3e-26 92.3 9.0 4.7e-06 27.2 0.8 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP84716.1 - 8e-08 32.5 0.3 0.11 12.8 0.0 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP84716.1 - 1e-06 27.7 7.8 0.44 9.1 0.1 4.9 3 2 2 5 5 5 4 Nucleoporin Nup120/160 DUF3929 PF13066.6 GAP84716.1 - 0.00053 20.0 0.2 1.1 9.4 0.1 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3929) BBS2_Mid PF14783.6 GAP84716.1 - 0.027 14.5 0.0 1.6 8.8 0.0 3.1 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Hira PF07569.11 GAP84716.1 - 0.12 12.0 0.1 6.5 6.4 0.0 3.1 3 0 0 3 3 3 0 TUP1-like enhancer of split Suppressor_APC PF11414.8 GAP84716.1 - 1.6 8.9 3.8 1.4 9.0 0.3 2.3 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein BCIP PF13862.6 GAP84718.1 - 1.8e-69 233.6 0.2 2.2e-69 233.4 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Cyclin_N PF00134.23 GAP84719.1 - 0.00034 20.3 0.1 0.0051 16.5 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain WD40 PF00400.32 GAP84721.1 - 1.3e-11 44.9 2.6 0.072 14.0 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP84721.1 - 0.053 13.8 0.0 40 4.6 0.0 3.4 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ATP_bind_1 PF03029.17 GAP84722.1 - 2.4e-78 263.3 0.0 3e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 GAP84722.1 - 0.0045 16.0 0.0 0.0081 15.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 GAP84722.1 - 0.038 13.3 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_31 PF13614.6 GAP84722.1 - 0.14 12.0 0.0 8.1 6.3 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAP84722.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_2 PF00891.18 GAP84723.1 - 4.2e-23 81.8 0.0 7.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DHHC PF01529.20 GAP84724.1 - 0.35 11.0 3.0 0.61 10.2 3.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Promethin PF16015.5 GAP84724.1 - 0.36 10.8 9.6 0.73 9.8 9.6 1.4 1 0 0 1 1 1 0 Promethin Ank_2 PF12796.7 GAP84725.1 - 4.7e-131 427.7 10.4 1.8e-16 60.4 0.2 12.9 3 3 11 15 15 15 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP84725.1 - 1.4e-101 331.7 25.2 1.1e-11 45.0 0.0 16.6 10 3 6 17 17 17 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP84725.1 - 1.1e-86 274.3 19.2 0.0011 19.2 0.0 26.0 25 1 1 26 26 25 17 Ankyrin repeat Ank_5 PF13857.6 GAP84725.1 - 1.8e-85 279.9 34.1 4e-07 30.2 0.1 21.4 8 5 13 21 21 21 20 Ankyrin repeats (many copies) Ank PF00023.30 GAP84725.1 - 2.8e-76 248.9 38.5 0.00018 21.8 0.2 24.5 26 0 0 26 26 26 18 Ankyrin repeat NACHT PF05729.12 GAP84725.1 - 6.4e-07 29.4 0.0 1e-05 25.5 0.0 2.8 2 1 0 2 2 1 1 NACHT domain Abhydrolase_6 PF12697.7 GAP84725.1 - 0.0015 19.2 0.1 0.0015 19.2 0.1 3.7 4 1 0 4 4 4 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAP84725.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein AAA_19 PF13245.6 GAP84725.1 - 0.016 15.5 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAP84725.1 - 0.025 14.9 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 1 0 AAA ATPase domain SplA PF11132.8 GAP84725.1 - 0.027 14.2 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator protein (SplA) AAA_14 PF13173.6 GAP84725.1 - 0.054 13.5 0.2 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAP84725.1 - 0.082 13.2 0.0 0.3 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 GAP84725.1 - 0.12 12.5 0.0 1.7 8.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA PF00004.29 GAP84725.1 - 0.15 12.5 0.0 0.47 10.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 GAP84725.1 - 0.18 10.9 0.0 0.48 9.5 0.0 1.8 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 VWA_3_C PF18571.1 GAP84725.1 - 3.7 7.5 6.9 28 4.7 0.1 4.9 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain MoeA_N PF03453.17 GAP84726.1 - 6.2e-40 136.5 3.6 1.3e-39 135.4 3.6 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 GAP84726.1 - 7e-33 113.3 1.8 9.3e-25 87.0 0.2 2.8 3 0 0 3 3 3 2 Probable molybdopterin binding domain MoeA_C PF03454.15 GAP84726.1 - 4.4e-17 62.0 0.0 1.3e-16 60.6 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 GAP84726.1 - 1.1 8.6 12.2 1.6 8.1 12.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pkinase PF00069.25 GAP84727.1 - 2.3e-28 99.3 0.1 4.9e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84727.1 - 1.9e-16 60.1 0.0 2.9e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP84727.1 - 0.043 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAP84727.1 - 0.17 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2235 PF09994.9 GAP84728.1 - 6.5e-63 212.8 0.0 1.1e-62 212.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF5026 PF16429.5 GAP84728.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) Trigger_C PF05698.14 GAP84728.1 - 0.12 12.3 0.1 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus Methyltransf_11 PF08241.12 GAP84729.1 - 1.9e-14 54.1 0.0 3.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP84729.1 - 3.1e-13 50.2 0.0 6.2e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP84729.1 - 4.3e-13 49.1 0.0 6.9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAP84729.1 - 7.1e-12 45.5 0.0 1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP84729.1 - 2.4e-10 41.0 0.0 4.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP84729.1 - 3.7e-10 39.8 0.0 6.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAP84729.1 - 1.4e-05 25.1 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP84729.1 - 0.0025 17.4 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain zf_C2H2_13 PF18508.1 GAP84730.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Zinc finger domain DUF2781 PF10914.8 GAP84731.1 - 4.2e-36 124.6 7.9 4.8e-36 124.4 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) EMG1 PF03587.14 GAP84731.1 - 0.23 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase SAP130_C PF16014.5 GAP84732.1 - 0.17 10.9 1.3 0.19 10.8 1.3 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DUF5393 PF17371.2 GAP84733.1 - 0.13 10.3 1.2 5.8 4.9 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5393) Tannase PF07519.11 GAP84734.1 - 9.7e-132 440.2 5.8 1.1e-131 440.0 5.8 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase U-box PF04564.15 GAP84736.1 - 1e-17 64.1 0.0 1.8e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 U-box domain CHIP_TPR_N PF18391.1 GAP84736.1 - 7.7e-05 23.4 9.3 0.00014 22.6 9.3 1.4 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_2 PF07719.17 GAP84736.1 - 0.0018 18.2 1.8 0.62 10.3 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP84736.1 - 0.046 13.9 1.2 0.14 12.4 0.8 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-NOSIP PF15906.5 GAP84736.1 - 0.078 13.1 0.0 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_17 PF13431.6 GAP84736.1 - 0.24 11.9 1.7 2.1 8.9 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat CFEM PF05730.11 GAP84737.1 - 2.3e-07 30.8 6.9 3.9e-07 30.1 6.9 1.3 1 0 0 1 1 1 1 CFEM domain DUF5476 PF17570.2 GAP84738.1 - 0.18 12.2 0.1 0.31 11.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5476) HET PF06985.11 GAP84739.1 - 7.9e-05 23.0 1.0 0.0029 18.0 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Nucleoporin_N PF08801.11 GAP84740.1 - 9.6e-88 294.8 0.2 1.3e-87 294.3 0.2 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 GAP84740.1 - 3.1e-53 181.4 0.4 2.7e-52 178.3 0.2 2.0 1 1 1 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal K_oxygenase PF13434.6 GAP84740.1 - 0.085 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) adh_short PF00106.25 GAP84741.1 - 5.4e-39 133.7 0.0 7.1e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84741.1 - 1.8e-22 80.1 0.0 2.5e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP84741.1 - 1.6e-06 28.1 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 GAP84741.1 - 0.0057 16.6 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family Polysacc_synt_2 PF02719.15 GAP84741.1 - 0.006 15.7 0.0 0.0081 15.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAP84741.1 - 0.059 13.3 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Erg28 PF03694.13 GAP84742.1 - 4.2e-43 146.2 0.5 5.2e-43 145.9 0.5 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.22 GAP84743.1 - 3.1e-69 233.1 0.0 1e-67 228.2 0.0 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 GAP84743.1 - 6.9e-60 201.6 0.1 1.1e-59 200.9 0.1 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 GAP84743.1 - 0.021 15.6 0.0 0.07 13.9 0.0 1.9 2 0 0 2 2 2 0 HIT domain TRAP-gamma PF07074.12 GAP84743.1 - 0.043 13.4 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) ZZ PF00569.17 GAP84744.1 - 3.3e-10 39.6 3.6 5.9e-10 38.8 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 GAP84744.1 - 7.3e-09 35.7 0.0 1.9e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 GAP84744.1 - 1.8e-05 25.0 0.0 5.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain O-FucT PF10250.9 GAP84745.1 - 1.7e-22 80.6 0.0 3.9e-22 79.4 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Rhodanese PF00581.20 GAP84746.1 - 5.5e-12 46.2 0.0 8.3e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Med13_C PF06333.12 GAP84747.1 - 0.031 13.6 5.6 0.035 13.4 5.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain MAP65_ASE1 PF03999.12 GAP84747.1 - 0.34 9.5 14.7 0.4 9.3 14.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) NUDE_C PF04880.13 GAP84747.1 - 0.91 10.0 14.7 1.2 9.5 14.7 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Glypican PF01153.19 GAP84747.1 - 1.2 7.9 4.7 6.4 5.5 0.7 2.0 1 1 1 2 2 2 0 Glypican ORC6 PF05460.13 GAP84747.1 - 2.2 7.5 14.6 2.8 7.1 14.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Macoilin PF09726.9 GAP84747.1 - 8.4 4.8 6.2 9.6 4.6 6.2 1.1 1 0 0 1 1 1 0 Macoilin family MSP1_C PF07462.11 GAP84747.1 - 8.7 4.9 10.5 11 4.6 10.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Methyltransf_2 PF00891.18 GAP84748.1 - 4.5e-20 71.8 0.0 6.5e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 GAP84748.1 - 0.013 15.5 0.3 0.038 14.0 0.1 2.0 2 0 0 2 2 2 0 Dimerisation domain AMP-binding PF00501.28 GAP84749.1 - 5.8e-44 150.4 0.0 9.7e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 GAP84749.1 - 1.2e-27 97.6 0.0 2.9e-27 96.3 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 GAP84749.1 - 2.5e-13 50.2 0.1 2.5e-13 50.2 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 GAP84749.1 - 0.0047 17.6 0.1 0.015 15.9 0.1 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP84749.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP84749.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aldo_ket_red PF00248.21 GAP84750.1 - 2.6e-42 145.0 0.0 3.5e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 GAP84751.1 - 9.4e-11 42.1 2.0 0.00053 20.7 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP84751.1 - 0.0029 17.9 0.0 27 5.1 0.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP84751.1 - 0.033 13.1 0.1 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BNR PF02012.20 GAP84751.1 - 0.16 12.0 0.1 0.76 10.0 0.1 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat Glyco_hydro_75 PF07335.11 GAP84752.1 - 1.1e-64 217.6 0.4 1.4e-64 217.3 0.4 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 MFS_1 PF07690.16 GAP84753.1 - 2.1e-43 148.6 34.4 2.1e-43 148.6 34.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP84753.1 - 2.4e-15 56.4 3.3 2.4e-15 56.4 3.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 GAP84753.1 - 0.1 10.9 7.0 0.96 7.7 1.1 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cutinase PF01083.22 GAP84754.1 - 1.1e-32 113.5 4.3 1.5e-32 113.0 4.3 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAP84754.1 - 0.0033 17.0 0.3 0.0091 15.6 0.0 1.7 2 0 0 2 2 2 1 PE-PPE domain VirJ PF06057.11 GAP84754.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Senescence PF06911.12 GAP84754.1 - 0.076 13.3 0.0 0.16 12.2 0.0 1.4 1 1 0 1 1 1 0 Senescence-associated protein P4Ha_N PF08336.11 GAP84755.1 - 0.13 12.2 10.1 1.4 8.9 2.0 2.7 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3453 PF11935.8 GAP84756.1 - 2.4e-66 223.6 0.0 2.4e-65 220.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Abhydrolase_1 PF00561.20 GAP84756.1 - 0.13 11.8 0.2 0.29 10.7 0.1 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Coiled-coil_56 PF09813.9 GAP84757.1 - 0.0055 16.7 0.0 0.0055 16.7 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Sds3 PF08598.11 GAP84758.1 - 1.5e-16 61.1 3.4 1.5e-16 61.1 3.4 2.4 2 2 0 2 2 2 1 Sds3-like Glyco_hydro_47 PF01532.20 GAP84759.1 - 1.3e-171 571.6 0.0 1.4e-171 571.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Asp PF00026.23 GAP84760.1 - 0.0025 17.3 0.0 0.0054 16.2 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF1206 PF06724.11 GAP84760.1 - 0.017 15.2 0.2 0.037 14.1 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) CD99L2 PF12301.8 GAP84760.1 - 0.097 13.0 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 ADIP PF11559.8 GAP84762.1 - 0.0025 17.9 2.4 0.0025 17.9 2.4 1.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 GAP84762.1 - 0.0062 16.4 0.4 0.017 14.9 0.4 1.7 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mod_r PF07200.13 GAP84762.1 - 0.013 15.6 1.4 0.013 15.6 1.4 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein NRBF2_MIT PF17169.4 GAP84762.1 - 0.017 15.3 0.9 0.041 14.1 0.9 1.6 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Cluap1 PF10234.9 GAP84762.1 - 0.039 13.3 0.6 0.1 12.0 0.6 1.7 1 0 0 1 1 1 0 Clusterin-associated protein-1 TMF_TATA_bd PF12325.8 GAP84762.1 - 0.062 13.5 0.8 0.062 13.5 0.8 2.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Ax_dynein_light PF10211.9 GAP84762.1 - 0.11 12.4 4.3 0.21 11.5 1.8 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain BRE1 PF08647.11 GAP84762.1 - 0.18 11.9 6.6 0.51 10.5 2.4 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 GAP84762.1 - 0.19 11.5 6.0 0.8 9.5 3.4 2.8 3 0 0 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.8 GAP84762.1 - 0.27 11.3 8.8 0.11 12.5 4.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Herpes_UL6 PF01763.16 GAP84762.1 - 0.27 9.7 0.3 0.41 9.1 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like FliD_C PF07195.12 GAP84762.1 - 0.31 10.4 4.0 0.85 9.0 4.0 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus GrpE PF01025.19 GAP84762.1 - 0.39 10.4 2.7 1.1 8.9 2.7 1.7 1 0 0 1 1 1 0 GrpE ZapB PF06005.12 GAP84762.1 - 0.7 10.4 11.4 0.053 14.0 3.8 2.7 3 0 0 3 3 3 0 Cell division protein ZapB YabA PF06156.13 GAP84762.1 - 0.96 10.1 8.2 0.17 12.5 1.0 2.8 3 0 0 3 3 3 0 Initiation control protein YabA bZIP_2 PF07716.15 GAP84762.1 - 1.1 9.3 9.0 1.1 9.4 3.1 3.0 2 1 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.18 GAP84762.1 - 1.3 9.4 3.7 1.5 9.2 1.3 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family APG6_N PF17675.1 GAP84762.1 - 1.9 9.0 6.7 0.26 11.8 1.5 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DHR10 PF18595.1 GAP84762.1 - 2 8.5 9.7 0.4 10.7 5.5 2.0 2 0 0 2 2 1 0 Designed helical repeat protein 10 domain DivIVA PF05103.13 GAP84762.1 - 3.2 7.8 10.0 3.7 7.7 1.5 2.7 3 0 0 3 3 3 0 DivIVA protein bZIP_1 PF00170.21 GAP84762.1 - 4.1 7.6 11.1 12 6.0 4.8 3.0 2 1 1 3 3 3 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 GAP84762.1 - 5.4 7.2 9.1 2 8.6 5.1 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 CDH-cyt PF16010.5 GAP84765.1 - 2e-66 223.2 3.1 2.8e-65 219.4 2.2 2.4 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 GAP84765.1 - 3.9e-27 95.4 0.1 7e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP84765.1 - 9.7e-24 84.5 0.4 1.8e-23 83.7 0.4 1.5 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 GAP84765.1 - 8.1e-10 38.5 13.2 2.6e-09 36.9 13.2 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.24 GAP84765.1 - 6.5e-09 35.4 0.3 0.00022 20.4 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAP84765.1 - 4.9e-05 23.5 0.0 0.00018 21.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP84765.1 - 6.4e-05 22.7 1.2 0.0006 19.5 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP84765.1 - 0.0014 17.9 0.1 0.0029 16.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP84765.1 - 0.002 16.9 0.1 0.0031 16.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 GAP84765.1 - 0.018 14.4 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAP84765.1 - 0.026 13.8 1.3 0.08 12.2 1.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAP84765.1 - 0.033 13.2 0.1 0.05 12.6 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAP84765.1 - 0.054 12.7 0.1 0.087 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 GAP84765.1 - 0.063 13.8 0.0 0.43 11.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP84765.1 - 0.12 11.6 2.0 0.12 11.6 0.6 1.7 2 0 0 2 2 2 0 Thi4 family Mpv17_PMP22 PF04117.12 GAP84766.1 - 4.7e-15 55.6 0.5 1.1e-14 54.4 0.5 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ank_2 PF12796.7 GAP84767.1 - 1.1e-26 93.2 6.2 4.5e-05 23.9 0.0 8.4 7 1 1 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP84767.1 - 2.1e-16 60.0 5.7 0.0085 16.7 0.0 9.5 8 2 0 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP84767.1 - 1.1e-12 47.0 6.3 3.3 8.6 0.0 13.0 14 2 1 15 15 15 1 Ankyrin repeat Ank PF00023.30 GAP84767.1 - 2.9e-11 43.3 18.0 0.0036 17.7 0.0 9.6 10 0 0 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 GAP84767.1 - 7.8e-10 38.8 5.6 4.7e-06 26.8 0.0 6.3 7 0 0 7 7 7 1 Ankyrin repeats (many copies) HpaB_N PF11794.8 GAP84767.1 - 0.027 14.1 0.8 0.058 13.1 0.8 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Ank_2 PF12796.7 GAP84768.1 - 1.3e-14 54.5 4.3 0.0022 18.6 0.0 6.1 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP84768.1 - 9.3e-08 31.8 7.1 36 5.4 0.0 9.5 11 0 0 11 11 11 1 Ankyrin repeat Ank_4 PF13637.6 GAP84768.1 - 3.7e-07 30.6 0.7 1.7 9.3 0.0 6.4 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP84768.1 - 0.00053 20.2 2.6 3.8 7.9 0.0 6.8 8 2 1 9 9 9 1 Ankyrin repeats (many copies) Epimerase PF01370.21 GAP84769.1 - 1.2e-48 165.7 0.0 1.5e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP84769.1 - 1.4e-48 166.0 0.0 2.1e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAP84769.1 - 6e-17 61.5 0.0 3.8e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAP84769.1 - 1.2e-11 44.4 0.0 5.5e-10 38.8 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAP84769.1 - 4.8e-11 42.3 0.0 6.6e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 GAP84769.1 - 8.6e-08 31.9 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 GAP84769.1 - 7.6e-07 28.6 0.0 0.00014 21.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 GAP84769.1 - 5e-05 23.3 0.0 8.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAP84769.1 - 0.00017 21.5 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAP84769.1 - 0.013 15.1 0.0 0.069 12.7 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 GAP84769.1 - 0.015 14.8 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.6 GAP84769.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Sad1_UNC PF07738.13 GAP84770.1 - 3e-07 30.5 0.2 1.1e-06 28.7 0.2 2.0 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Ufd2P_core PF10408.9 GAP84770.1 - 0.044 12.4 0.9 0.065 11.8 0.9 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core UL42 PF17638.2 GAP84770.1 - 0.07 13.1 4.8 1.6 8.7 0.4 2.8 2 0 0 2 2 2 0 HCMV UL42 DEAD PF00270.29 GAP84771.1 - 1e-46 158.9 0.0 1.7e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP84771.1 - 4.7e-21 75.2 0.0 2.4e-20 72.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAP84771.1 - 1e-20 73.7 0.0 2.4e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAP84771.1 - 2.4e-07 30.9 0.0 9.2e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit GMC_oxred_N PF00732.19 GAP84772.1 - 3.9e-50 170.9 0.0 5.4e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP84772.1 - 3.4e-37 128.2 0.0 5.3e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAP84772.1 - 7.6e-06 25.2 0.1 1.1e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAP84772.1 - 0.00017 21.7 0.1 0.0007 19.8 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP84772.1 - 0.00026 20.7 0.1 0.0011 18.6 0.1 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP84772.1 - 0.00041 19.6 0.0 0.031 13.4 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP84772.1 - 0.0017 17.7 0.0 0.0058 15.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAP84772.1 - 0.0072 15.2 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 GAP84772.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 GAP84772.1 - 0.018 15.6 0.0 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP84772.1 - 0.061 13.3 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAP84772.1 - 0.12 11.7 0.1 14 4.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Aldedh PF00171.22 GAP84773.1 - 7.6e-153 509.3 0.0 9.9e-153 509.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DnaB_bind PF10410.9 GAP84773.1 - 0.19 11.9 0.1 0.49 10.6 0.1 1.6 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase HAUS6_N PF14661.6 GAP84774.1 - 8.6e-56 189.1 1.9 9.1e-56 189.0 0.0 2.0 3 0 0 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus Pyr_redox_2 PF07992.14 GAP84777.1 - 8.8e-12 44.8 0.3 4.6e-07 29.4 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP84777.1 - 0.0041 16.3 3.1 0.053 12.6 0.7 2.8 2 1 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 GAP84777.1 - 0.014 14.7 0.7 0.032 13.5 0.7 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 GAP84777.1 - 0.014 14.7 1.2 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP84777.1 - 0.093 12.0 0.8 0.2 10.9 0.3 1.7 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 GAP84777.1 - 0.12 11.4 0.5 0.2 10.7 0.5 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 GAP84777.1 - 0.42 10.1 2.8 1 8.9 2.8 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase FNIP_N PF14636.6 GAP84778.1 - 1.2e-40 140.0 0.5 1.2e-40 140.0 0.5 4.8 4 1 0 5 5 5 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 GAP84778.1 - 0.2 11.7 0.0 4.2 7.3 0.1 2.5 2 1 1 3 3 3 0 Folliculin-interacting protein middle domain PHP PF02811.19 GAP84779.1 - 3.1e-11 43.8 0.0 4.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 PHP domain DUF1983 PF09327.11 GAP84779.1 - 0.03 14.4 1.8 0.075 13.1 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1983) SSP160 PF06933.11 GAP84779.1 - 5.8 5.0 14.4 7.8 4.6 14.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RRM_1 PF00076.22 GAP84780.1 - 2.4e-07 30.5 0.4 8e-07 28.8 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 GAP84780.1 - 1.7e-06 28.2 0.0 3.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 GAP84780.1 - 6.3e-05 22.8 4.6 0.00012 21.9 4.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 GAP84780.1 - 0.00022 21.2 0.0 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif FbpA PF05833.11 GAP84780.1 - 0.0078 15.0 0.9 0.012 14.4 0.9 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) zf_CCCH_4 PF18345.1 GAP84780.1 - 0.0083 16.2 5.5 0.016 15.2 5.5 1.5 1 0 0 1 1 1 1 Zinc finger domain DUF1330 PF07045.11 GAP84780.1 - 0.063 13.6 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) HAUS6_N PF14661.6 GAP84780.1 - 0.15 11.6 5.4 0.26 10.9 5.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus zf-CCCH_4 PF18044.1 GAP84780.1 - 0.62 9.9 6.4 1.1 9.2 6.4 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger RRM_3 PF08777.11 GAP84780.1 - 1.3 9.1 8.0 0.56 10.3 0.1 3.1 3 0 0 3 3 3 0 RNA binding motif HrpJ PF07201.11 GAP84780.1 - 1.4 9.2 11.2 1.9 8.8 10.1 1.7 2 0 0 2 2 2 0 HrpJ-like domain PHM7_cyt PF14703.6 GAP84780.1 - 1.9 8.7 5.0 8.2 6.6 0.1 2.8 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Cation_efflux PF01545.21 GAP84782.1 - 8.8e-49 165.9 10.7 1.1e-48 165.6 10.7 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 GAP84782.1 - 0.0072 15.5 1.4 0.0072 15.5 1.4 2.1 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component CD20 PF04103.15 GAP84782.1 - 0.02 15.0 1.7 1.1 9.3 0.5 2.6 2 0 0 2 2 2 0 CD20-like family TMEM43 PF07787.12 GAP84782.1 - 6.4 6.1 7.8 2.3 7.5 0.9 2.5 2 0 0 2 2 2 0 Transmembrane protein 43 adh_short PF00106.25 GAP84783.1 - 1.6e-28 99.5 1.8 7.5e-26 90.8 0.7 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84783.1 - 2.3e-17 63.3 0.2 2e-15 57.0 0.2 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP84783.1 - 2.7e-07 30.7 0.2 6.7e-07 29.4 0.1 1.7 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAP84783.1 - 0.0039 16.4 0.1 0.0061 15.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAP84783.1 - 0.0057 16.1 0.7 0.018 14.5 0.7 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP84783.1 - 0.016 14.6 0.4 0.054 12.9 0.4 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase IML1 PF12257.8 GAP84784.1 - 5.9e-115 383.3 0.0 8.7e-115 382.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 GAP84784.1 - 1.9e-27 95.1 0.2 3.9e-27 94.1 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Na_Ca_ex PF01699.24 GAP84785.1 - 1.6e-42 145.0 36.2 1.1e-21 77.3 12.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ATP-synt_8 PF00895.20 GAP84785.1 - 0.091 13.2 0.3 0.36 11.3 0.3 2.1 1 0 0 1 1 1 0 ATP synthase protein 8 Tad PF13400.6 GAP84785.1 - 0.33 11.3 10.9 2.7 8.4 0.7 3.7 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like PTR2 PF00854.21 GAP84786.1 - 6.7e-40 137.1 1.5 1.1e-39 136.4 1.5 1.3 1 0 0 1 1 1 1 POT family CLP1_P PF16575.5 GAP84788.1 - 1.6e-34 119.4 0.0 2.2e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 GAP84788.1 - 1.2e-30 106.3 0.0 2.1e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 GAP84788.1 - 4.2e-27 94.2 0.0 6.9e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor MMR_HSR1 PF01926.23 GAP84788.1 - 2.8e-05 24.2 0.3 0.00014 21.9 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 GAP84788.1 - 0.00023 21.0 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 GAP84788.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 GAP84788.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 GAP84788.1 - 0.05 12.7 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 FeoB_N PF02421.18 GAP84788.1 - 0.13 11.7 0.0 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 GAP84788.1 - 0.15 11.4 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein KTI12 PF08433.10 GAP84788.1 - 0.2 11.1 0.0 1.7 8.0 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IPK PF03770.16 GAP84789.1 - 4.3e-47 160.6 0.0 5.8e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.10 GAP84790.1 - 1.1e-121 406.8 0.0 1.4e-121 406.4 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Hist_deacetyl PF00850.19 GAP84791.1 - 3.4e-54 184.4 0.3 5.3e-54 183.8 0.3 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 GAP84791.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region ParA PF10609.9 GAP84792.1 - 5.3e-94 314.3 0.0 6.2e-94 314.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAP84792.1 - 8.5e-09 35.5 0.0 1.6e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAP84792.1 - 0.00072 19.5 0.1 0.0064 16.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 GAP84792.1 - 0.003 16.8 1.2 0.021 14.0 0.9 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 GAP84792.1 - 0.0033 17.0 0.5 0.0058 16.2 0.5 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 GAP84792.1 - 0.0096 15.8 0.1 0.58 9.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAP84792.1 - 0.022 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAP84792.1 - 0.032 14.2 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 GAP84792.1 - 0.036 14.1 0.1 0.066 13.2 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 GAP84792.1 - 0.048 14.0 0.1 0.09 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain Fer4_NifH PF00142.18 GAP84792.1 - 0.083 12.3 0.0 2.3 7.6 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNA_helicase PF00910.22 GAP84792.1 - 0.095 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MipZ PF09140.11 GAP84792.1 - 0.19 11.0 0.1 0.42 9.8 0.1 1.6 1 1 0 1 1 1 0 ATPase MipZ Cofilin_ADF PF00241.20 GAP84793.1 - 4.1e-16 58.9 0.0 5.3e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Glyco_hydro_43 PF04616.14 GAP84794.1 - 4.7e-42 144.3 4.0 5.3e-42 144.1 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HTH_Tnp_Tc5 PF03221.16 GAP84795.1 - 8.2e-17 61.0 4.8 5.3e-06 26.4 0.1 6.1 5 1 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.11 GAP84795.1 - 6.5e-15 54.8 1.0 6.5e-15 54.8 1.0 3.2 4 0 0 4 4 4 1 Homeobox KN domain Homeodomain PF00046.29 GAP84795.1 - 5.1e-05 23.0 0.2 0.00013 21.7 0.2 1.7 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 GAP84795.1 - 0.00059 20.1 13.5 0.044 14.2 3.9 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP84795.1 - 0.0035 18.0 3.8 0.0035 18.0 3.8 4.7 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP84795.1 - 0.48 10.8 2.1 2.5 8.5 2.1 2.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 GAP84795.1 - 3.3 7.9 9.1 0.93 9.7 2.6 2.5 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 GAP84795.1 - 4.4 7.9 7.0 32 5.2 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain DUF3425 PF11905.8 GAP84798.1 - 5.4e-12 45.8 1.5 1.7e-11 44.1 1.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) MTHFR PF02219.17 GAP84800.1 - 7.7e-110 366.7 0.0 1.2e-109 366.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MoCF_biosynth PF00994.24 GAP84801.1 - 1e-34 119.3 0.0 1.6e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain THEG PF14912.6 GAP84801.1 - 0.046 14.2 0.6 0.15 12.5 0.2 1.9 2 0 0 2 2 2 0 Testicular haploid expressed repeat Ras PF00071.22 GAP84802.1 - 6.5e-55 185.2 0.1 7.5e-55 184.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP84802.1 - 1.8e-18 66.9 0.0 2.5e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP84802.1 - 1.3e-06 28.0 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAP84802.1 - 0.00034 20.6 0.4 0.59 10.0 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAP84802.1 - 0.0013 18.7 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAP84802.1 - 0.0027 17.3 0.3 0.017 14.7 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF4309 PF14172.6 GAP84802.1 - 0.033 14.2 0.0 8 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4309) Ldh_1_N PF00056.23 GAP84802.1 - 0.14 12.2 0.0 0.48 10.5 0.0 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Zn_clus PF00172.18 GAP84803.1 - 0.0042 17.2 4.6 0.0042 17.2 4.6 3.6 3 1 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dehydrin PF00257.19 GAP84804.1 - 4.2 7.9 13.4 10 6.6 0.0 2.7 1 1 1 2 2 2 0 Dehydrin Zn_clus PF00172.18 GAP84805.1 - 1.1e-06 28.7 12.5 1.7e-06 28.0 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 GAP84806.1 - 1e-17 64.2 1.0 1.3e-17 63.9 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP84806.1 - 1.2e-13 51.1 0.3 1.7e-13 50.7 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP84806.1 - 1.9e-10 41.0 0.4 2.7e-10 40.5 0.4 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAP84806.1 - 0.0033 16.6 0.0 0.0048 16.1 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAP84806.1 - 0.098 12.1 0.2 0.16 11.4 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 GAP84807.1 - 9.4e-77 258.7 0.0 1.2e-76 258.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1932 PF09130.11 GAP84808.1 - 4.7e-25 87.3 0.2 1.3e-24 85.9 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 GAP84808.1 - 4.9e-09 36.6 0.1 1.2e-08 35.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAP84808.1 - 1.5e-07 31.7 0.0 2.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 GAP84808.1 - 0.0021 17.4 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GAP84808.1 - 0.0065 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 GAP84808.1 - 0.12 11.3 0.1 0.2 10.6 0.1 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase RRM_1 PF00076.22 GAP84809.1 - 7.1e-18 64.2 0.0 1.3e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 GAP84809.1 - 9.9e-07 29.2 7.5 9.9e-07 29.2 7.5 3.0 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 SET PF00856.28 GAP84811.1 - 1.2e-14 55.1 0.1 6.7e-14 52.6 0.0 2.2 2 1 0 2 2 2 1 SET domain PI-PLC-X PF00388.19 GAP84812.1 - 8e-12 45.0 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DAGAT PF03982.13 GAP84813.1 - 1.7e-95 319.3 0.0 2.3e-95 318.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase TPT PF03151.16 GAP84814.1 - 2.3e-19 69.8 11.9 3.1e-19 69.4 11.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAP84814.1 - 4.3e-05 23.7 34.1 0.012 15.8 16.9 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 GAP84814.1 - 0.034 13.3 14.4 0.057 12.6 14.4 1.3 1 0 0 1 1 1 0 UAA transporter family PUNUT PF16913.5 GAP84814.1 - 0.036 13.3 13.9 0.021 14.1 1.1 2.6 2 1 1 3 3 3 0 Purine nucleobase transmembrane transport FAM176 PF14851.6 GAP84814.1 - 0.28 10.8 4.5 0.53 9.9 0.1 2.5 2 0 0 2 2 2 0 FAM176 family RRM_1 PF00076.22 GAP84815.1 - 5.5e-16 58.1 0.0 5.5e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytotoxic PF09000.10 GAP84815.1 - 0.01 16.2 0.7 0.024 15.0 0.0 1.9 2 0 0 2 2 2 0 Cytotoxic 6PGD PF00393.19 GAP84816.1 - 3.5e-127 423.7 0.0 4.4e-127 423.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 GAP84816.1 - 2.1e-51 174.2 0.0 3.5e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ANT PF03374.14 GAP84816.1 - 0.048 14.0 0.0 6 7.2 0.0 2.8 3 0 0 3 3 3 0 Phage antirepressor protein KilAC domain NAD_binding_11 PF14833.6 GAP84816.1 - 0.073 13.3 0.1 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.19 GAP84816.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoglycerate kinase F420_oxidored PF03807.17 GAP84816.1 - 0.14 12.8 0.0 0.48 11.0 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SWI-SNF_Ssr4 PF08549.10 GAP84817.1 - 3.9e-255 849.0 18.3 1.7e-237 790.6 9.1 2.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) RRM_1 PF00076.22 GAP84819.1 - 1.2e-11 44.2 0.0 8.3e-10 38.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SH3_2 PF07653.17 GAP84821.1 - 1.4e-09 37.5 0.0 2.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAP84821.1 - 2e-09 36.9 0.1 4.5e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAP84821.1 - 7.6e-08 32.1 0.1 1.7e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF572 PF04502.13 GAP84821.1 - 0.0051 16.5 3.2 0.0084 15.8 3.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) DNase-RNase PF02577.14 GAP84821.1 - 0.034 13.8 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Bifunctional nuclease RPAP2_Rtr1 PF04181.13 GAP84822.1 - 1.5e-22 79.7 0.1 2.8e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Zein-binding PF04576.15 GAP84822.1 - 0.059 13.7 2.1 0.12 12.6 2.1 1.5 1 0 0 1 1 1 0 Zein-binding Ribosomal_S17e PF00833.18 GAP84823.1 - 3.5e-57 191.6 0.1 4.2e-57 191.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 GAP84824.1 - 2.4e-120 402.5 0.1 2.8e-120 402.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF1681 PF07933.14 GAP84825.1 - 2.3e-55 186.4 0.0 2.8e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) GGDEF_2 PF17853.1 GAP84825.1 - 0.066 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 GGDEF-like domain CAP_N PF01213.19 GAP84825.1 - 0.79 9.1 5.2 1.9 7.9 4.6 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Neuraminidase PF18413.1 GAP84826.1 - 0.13 11.9 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Neuraminidase-like domain TGT PF01702.18 GAP84827.1 - 3.8e-140 467.0 0.0 4.5e-140 466.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase p450 PF00067.22 GAP84828.1 - 3.3e-32 111.8 0.2 5.6e-32 111.1 0.2 1.3 1 0 0 1 1 1 1 Cytochrome P450 GCK PF07802.11 GAP84828.1 - 0.016 15.6 0.1 0.087 13.3 0.0 2.0 2 0 0 2 2 2 0 GCK domain ATG101 PF07855.12 GAP84828.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Autophagy-related protein 101 DUF2034 PF10356.9 GAP84830.1 - 2.3e-27 95.6 0.0 6.4e-14 51.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 GAP84830.1 - 4.2e-08 33.2 0.0 7.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.8 GAP84831.1 - 9.9e-47 158.8 12.3 1.1e-46 158.7 12.3 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 GAP84831.1 - 0.021 14.9 1.6 0.021 14.9 1.6 2.7 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2841 PF11001.8 GAP84831.1 - 0.027 14.5 3.2 0.042 13.9 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2841) Spore_III_AB PF09548.10 GAP84831.1 - 0.052 13.6 4.2 0.074 13.2 4.2 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Cauli_AT PF03233.13 GAP84831.1 - 0.083 12.8 2.3 0.11 12.5 2.2 1.3 1 1 0 1 1 1 0 Aphid transmission protein DUF3090 PF11290.8 GAP84831.1 - 0.14 11.9 2.0 0.16 11.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) Fib_alpha PF08702.10 GAP84831.1 - 0.28 11.3 6.3 0.65 10.2 4.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HAD_2 PF13419.6 GAP84832.1 - 2.8e-14 53.6 0.0 4.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP84832.1 - 3.9e-11 43.7 0.0 4.2e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP84832.1 - 8.2e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like 5_nucleotid PF05761.14 GAP84832.1 - 0.0067 15.4 0.1 0.033 13.1 0.0 1.9 2 0 0 2 2 2 1 5' nucleotidase family HAD PF12710.7 GAP84832.1 - 0.012 16.0 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2664 PF10867.8 GAP84833.1 - 0.059 13.8 1.6 0.13 12.7 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) KH_1 PF00013.29 GAP84834.1 - 8e-35 118.5 3.1 6.2e-08 32.3 0.0 7.1 8 0 0 8 8 8 6 KH domain Peptidase_M16 PF00675.20 GAP84834.1 - 0.058 13.4 0.1 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Ins_allergen_rp PF06757.13 GAP84834.1 - 0.094 12.7 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Acetyltransf_1 PF00583.25 GAP84835.1 - 1.1e-08 35.3 0.0 2.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP84835.1 - 9.4e-08 32.1 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP84835.1 - 1.5e-06 28.5 0.0 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAP84835.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 GAP84835.1 - 0.035 14.2 0.0 3.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Nop14 PF04147.12 GAP84835.1 - 0.3 9.2 10.6 0.39 8.9 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAP84835.1 - 0.91 8.9 11.7 1.2 8.5 11.7 1.1 1 0 0 1 1 1 0 SDA1 DUF5523 PF17661.1 GAP84835.1 - 1.3 8.6 8.0 1.9 8.1 8.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Menin PF05053.13 GAP84835.1 - 1.8 6.9 5.4 2.4 6.4 5.4 1.1 1 0 0 1 1 1 0 Menin Cwf_Cwc_15 PF04889.12 GAP84835.1 - 2.2 7.9 18.5 3.3 7.4 18.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GAP84835.1 - 3.6 5.8 10.4 4.8 5.3 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Secretin_N_2 PF07655.13 GAP84835.1 - 4.5 7.9 13.5 3.6 8.2 10.9 2.0 2 0 0 2 2 2 0 Secretin N-terminal domain NOG1_N PF17835.1 GAP84836.1 - 3.4e-48 163.6 0.1 3.4e-48 163.6 0.1 2.2 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 GAP84836.1 - 9.1e-27 92.8 0.3 2.4e-26 91.5 0.3 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 GAP84836.1 - 4.3e-26 90.4 0.3 9.3e-26 89.4 0.3 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 GAP84836.1 - 8.5e-14 51.6 0.0 1.9e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAP84836.1 - 1.3e-07 31.3 0.0 2.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAP84836.1 - 0.00035 20.5 0.7 0.025 14.5 0.1 3.3 3 0 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 GAP84836.1 - 0.00091 19.3 0.1 1.9 8.5 0.0 2.8 1 1 1 2 2 2 2 Dynamin family Ras PF00071.22 GAP84836.1 - 0.097 12.3 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 Ras family PPV_E1_C PF00519.17 GAP84836.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Pribosyltran PF00156.27 GAP84837.1 - 5.5e-17 61.7 0.1 8.4e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Fungal_trans PF04082.18 GAP84838.1 - 1.4e-14 53.8 0.1 2.6e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 GAP84838.1 - 9.7e-07 28.9 6.6 1.8e-05 24.9 1.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 GAP84838.1 - 0.00075 19.7 4.4 0.0016 18.7 4.4 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 GAP84838.1 - 0.0012 19.5 15.1 0.063 14.1 5.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP84838.1 - 0.21 11.9 3.1 8.8 6.7 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 GAP84838.1 - 7.2 7.3 19.5 0.37 11.3 7.3 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type MRP-L47 PF06984.13 GAP84839.1 - 3.4e-22 78.3 0.3 6.1e-22 77.5 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.18 GAP84840.1 - 1e-191 637.2 0.0 1.2e-191 637.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 GAP84840.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAP84840.1 - 0.14 12.8 0.1 0.95 10.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IF-2B PF01008.17 GAP84841.1 - 8.4e-39 133.5 0.1 1.3e-38 132.9 0.1 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family RepL PF05732.11 GAP84841.1 - 0.00058 19.3 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) Methyltransf_33 PF10017.9 GAP84842.1 - 5.1e-86 288.6 0.0 7.6e-86 288.0 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 GAP84842.1 - 5.7e-20 72.0 0.8 1.9e-10 40.8 0.1 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 GAP84842.1 - 2.5e-05 24.8 0.2 6.7e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 DinB superfamily Asp_protease PF09668.10 GAP84843.1 - 2.4e-55 185.6 0.4 3.6e-55 185.1 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 GAP84843.1 - 4.6e-22 78.4 0.3 1.4e-21 76.8 0.2 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAP84843.1 - 2.7e-10 40.8 0.1 8e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 GAP84843.1 - 4.9e-08 32.6 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 GAP84843.1 - 2e-05 24.4 0.0 6.1e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 GAP84843.1 - 3e-05 24.2 0.0 5.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 GAP84843.1 - 0.00017 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Tropomyosin PF00261.20 GAP84843.1 - 0.002 17.5 0.2 0.0029 17.0 0.2 1.1 1 0 0 1 1 1 1 Tropomyosin UBA_4 PF14555.6 GAP84843.1 - 0.002 17.9 0.3 0.0049 16.6 0.3 1.6 1 0 0 1 1 1 1 UBA-like domain Sporozoite_P67 PF05642.11 GAP84843.1 - 0.1 10.7 1.4 0.14 10.2 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YukD PF08817.10 GAP84843.1 - 0.13 13.0 0.1 0.48 11.1 0.0 2.1 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD FliT PF05400.13 GAP84843.1 - 0.13 13.1 3.7 2.1 9.2 3.3 2.5 2 0 0 2 2 2 0 Flagellar protein FliT Methyltransf_8 PF05148.15 GAP84844.1 - 1.8e-57 194.7 0.0 2e-55 188.0 0.0 2.4 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 GAP84844.1 - 2.3e-05 24.9 0.0 7.2e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP84844.1 - 0.00029 21.5 0.0 0.022 15.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAP84844.1 - 0.0014 18.6 2.0 0.0027 17.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAP84844.1 - 0.048 13.2 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.6 GAP84844.1 - 0.071 12.9 0.0 6.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Fungal_trans_2 PF11951.8 GAP84845.1 - 2.6e-21 75.9 0.8 2.3e-11 43.1 0.1 2.9 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP84845.1 - 4.6e-08 33.1 12.0 8.1e-08 32.3 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP84845.1 - 0.013 14.5 1.1 0.031 13.3 0.1 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain Proteasome PF00227.26 GAP84847.1 - 5.5e-57 192.3 0.3 6.9e-57 192.0 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAP84847.1 - 1.6e-12 46.9 0.0 3.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 GAP84848.1 - 3.6e-65 220.6 0.1 6.2e-65 219.8 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 GAP84848.1 - 2e-60 204.9 2.7 2e-60 204.9 2.7 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal YqeY PF09424.10 GAP84849.1 - 1.2e-21 77.3 0.9 1.6e-21 76.9 0.9 1.1 1 0 0 1 1 1 1 Yqey-like protein Methyltransf_23 PF13489.6 GAP84850.1 - 2.9e-13 50.0 0.1 3.8e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP84850.1 - 1.4e-09 38.6 0.0 3.9e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP84850.1 - 2.5e-08 34.4 0.0 5.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP84850.1 - 4.5e-08 33.0 0.0 1.2e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP84850.1 - 4.5e-05 24.1 0.0 0.00021 22.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 GAP84850.1 - 0.0015 18.6 0.0 0.028 14.6 0.0 2.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 GAP84850.1 - 0.002 17.6 0.0 0.0043 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 GAP84850.1 - 0.02 14.2 0.0 0.081 12.2 0.0 2.0 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family PI3_PI4_kinase PF00454.27 GAP84852.1 - 7.3e-46 157.0 0.0 1.1e-45 156.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SelP_N PF04592.14 GAP84853.1 - 0.52 9.7 9.0 0.91 8.9 9.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SNF2_N PF00176.23 GAP84855.1 - 8.7e-74 248.3 0.0 1.3e-73 247.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP84855.1 - 4.4e-13 49.5 0.0 2.2e-12 47.3 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAP84855.1 - 0.0003 20.6 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 GAP84855.1 - 0.0041 17.1 3.3 0.0077 16.2 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAP84855.1 - 0.074 12.9 4.0 0.16 11.9 4.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 GAP84855.1 - 0.099 12.6 0.0 0.49 10.4 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DHC_N1 PF08385.12 GAP84855.1 - 0.21 10.2 0.9 0.34 9.5 0.0 1.7 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 Prok-RING_4 PF14447.6 GAP84855.1 - 0.24 11.3 3.2 0.53 10.2 3.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAP84855.1 - 2.4 8.4 4.8 6.3 7.0 4.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FA_desaturase PF00487.24 GAP84856.1 - 3.3e-18 66.4 9.2 3.3e-18 66.4 9.2 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAP84856.1 - 2.2e-17 63.0 0.0 7.3e-17 61.3 0.0 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 GAP84857.1 - 1e-09 38.1 0.0 6.1e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84857.1 - 1.1e-06 28.1 0.0 4.9e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 GAP84857.1 - 0.095 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 KIP1 PF07765.12 GAP84857.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 KIP1-like protein Lon_C PF05362.13 GAP84858.1 - 4.2e-65 219.1 0.0 8.5e-65 218.1 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 GAP84858.1 - 1.2e-32 113.5 0.0 3.4e-32 112.0 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 GAP84858.1 - 6.3e-22 78.4 0.0 1.6e-21 77.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 GAP84858.1 - 7.4e-08 32.3 0.0 2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 GAP84858.1 - 6.5e-07 29.4 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAP84858.1 - 9.7e-07 29.1 0.0 4.4e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 GAP84858.1 - 5e-05 22.4 0.0 0.00011 21.3 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 GAP84858.1 - 5.4e-05 23.5 0.0 0.00076 19.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAP84858.1 - 0.00014 21.7 0.0 0.00069 19.4 0.0 2.2 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAP84858.1 - 0.00025 21.5 0.1 0.0017 18.7 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain ClpB_D2-small PF10431.9 GAP84858.1 - 0.0027 17.7 3.5 0.0052 16.8 0.1 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_14 PF13173.6 GAP84858.1 - 0.0088 16.1 0.0 0.041 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAP84858.1 - 0.014 15.9 0.4 0.07 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAP84858.1 - 0.024 14.4 0.1 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 GAP84858.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DNTTIP1_dimer PF18192.1 GAP84858.1 - 0.037 14.4 0.4 1.6 9.2 0.2 2.9 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain RNA_helicase PF00910.22 GAP84858.1 - 0.056 13.8 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 GAP84858.1 - 0.057 13.3 0.2 0.15 12.0 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase SKI PF01202.22 GAP84858.1 - 0.058 13.5 0.1 0.51 10.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase AAA_7 PF12775.7 GAP84858.1 - 0.084 12.4 0.4 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GAP84858.1 - 0.091 12.7 0.2 1.6 8.6 0.0 2.5 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.27 GAP84858.1 - 0.13 12.8 0.7 0.87 10.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter PIN_12 PF16289.5 GAP84858.1 - 6.4 7.2 7.1 1.9 9.0 0.7 2.9 2 0 0 2 2 2 0 PIN domain ResIII PF04851.15 GAP84859.1 - 2.4e-24 86.2 0.0 5.9e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAP84859.1 - 2.8e-13 50.2 0.0 5.3e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAP84859.1 - 5.3e-10 39.4 0.0 5.5e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 GAP84859.1 - 0.00031 20.5 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 GAP84859.1 - 0.0079 15.5 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF2890 PF11081.8 GAP84859.1 - 0.025 14.7 0.1 0.066 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) ERCC3_RAD25_C PF16203.5 GAP84859.1 - 0.06 12.5 0.1 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 GAP84859.1 - 0.14 12.4 0.2 1.3 9.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain Aldo_ket_red PF00248.21 GAP84860.1 - 1.2e-71 241.3 0.3 1.3e-71 241.2 0.3 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_tail_X PF05489.12 GAP84860.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X DUF3425 PF11905.8 GAP84861.1 - 8.8e-17 61.2 0.0 2.2e-16 60.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) LAMTOR5 PF16672.5 GAP84861.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 bZIP_1 PF00170.21 GAP84861.1 - 2.5 8.3 11.8 4 7.6 11.8 1.2 1 0 0 1 1 1 0 bZIP transcription factor Myb_DNA-binding PF00249.31 GAP84862.1 - 0.0022 18.2 0.0 0.0078 16.4 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 GAP84863.1 - 1.9e-31 107.8 2.0 3.6e-31 107.0 2.0 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM PF04433.17 GAP84863.1 - 2.8e-30 104.5 0.2 6e-30 103.4 0.2 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 GAP84863.1 - 1.2e-10 41.4 0.1 2.6e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP84863.1 - 2.7e-06 27.5 0.3 5.7e-06 26.5 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAP84863.1 - 0.05 13.8 0.2 0.1 12.8 0.2 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF3439 PF11921.8 GAP84863.1 - 0.062 13.3 0.5 0.13 12.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ETF PF01012.21 GAP84864.1 - 4.2e-44 150.6 2.3 6.6e-44 150.0 2.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 GAP84864.1 - 3.2e-33 113.6 0.9 7e-33 112.5 0.9 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Pyr_redox_2 PF07992.14 GAP84865.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PFK PF00365.20 GAP84865.1 - 0.03 13.7 0.0 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 Phosphofructokinase DUF1275 PF06912.11 GAP84867.1 - 6.5e-45 153.4 9.1 8.4e-45 153.1 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PEP_mutase PF13714.6 GAP84868.1 - 1.8e-29 102.9 0.2 9.1e-21 74.4 0.1 2.2 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase ICL PF00463.21 GAP84868.1 - 1.6e-10 40.1 0.1 2.4e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family FAM176 PF14851.6 GAP84869.1 - 0.053 13.2 1.8 0.19 11.4 0.4 2.0 2 0 0 2 2 2 0 FAM176 family Treacle PF03546.14 GAP84869.1 - 0.36 9.6 0.2 0.63 8.8 0.0 1.5 2 0 0 2 2 2 0 Treacher Collins syndrome protein Treacle AATase PF07247.12 GAP84870.1 - 0.0058 15.2 0.0 0.0076 14.8 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase PLAC8 PF04749.17 GAP84871.1 - 9.5e-26 90.7 15.1 1.3e-25 90.3 15.1 1.2 1 0 0 1 1 1 1 PLAC8 family DUF5132 PF17195.4 GAP84873.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) DUF2057 PF09829.9 GAP84873.1 - 0.093 12.9 0.9 0.37 10.9 0.9 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DSBA PF01323.20 GAP84874.1 - 8.4e-26 90.9 0.0 1.1e-25 90.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain GST_N PF02798.20 GAP84875.1 - 5.8e-16 58.6 0.0 9.9e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP84875.1 - 2e-10 40.7 0.0 3.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAP84875.1 - 2.7e-10 40.3 0.1 7.3e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP84875.1 - 1.1e-08 34.9 0.0 2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAP84875.1 - 2.1e-07 31.2 0.0 6.5e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAP84875.1 - 1e-06 29.1 0.0 1.7e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAP84875.1 - 0.0044 16.8 0.0 0.0093 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 2-Hacid_dh_C PF02826.19 GAP84876.1 - 4e-40 137.1 0.0 2.4e-39 134.5 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP84876.1 - 5.9e-23 81.0 0.0 7.7e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 GAP84876.1 - 0.03 13.6 0.6 0.4 9.9 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 GAP84876.1 - 0.045 13.3 0.0 0.79 9.3 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 GAP84876.1 - 0.11 12.6 0.1 0.69 10.1 0.1 2.2 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Kelch_5 PF13854.6 GAP84877.1 - 0.00018 21.4 0.9 0.12 12.3 0.1 3.2 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 GAP84877.1 - 0.0011 19.2 9.6 0.019 15.3 0.9 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAP84877.1 - 0.0013 18.9 1.9 0.92 9.9 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 GAP84877.1 - 0.24 11.5 3.8 14 5.8 0.2 4.2 4 0 0 4 4 4 0 Galactose oxidase, central domain SKG6 PF08693.10 GAP84877.1 - 3.8 7.0 4.7 0.77 9.2 0.3 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF591 PF04569.14 GAP84878.1 - 0.068 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function CUE PF02845.16 GAP84879.1 - 2.3e-06 27.2 0.0 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 GAP84879.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) p450 PF00067.22 GAP84880.1 - 8e-66 222.7 0.0 9.7e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.21 GAP84881.1 - 1.9e-29 102.5 0.0 3e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAP84881.1 - 2.1e-27 95.4 0.0 4.3e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 GAP84881.1 - 9.5e-24 83.4 0.1 1.5e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 GAP84881.1 - 2.7e-05 24.4 0.0 0.00053 20.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 GAP84881.1 - 0.026 14.7 0.0 0.086 13.0 0.0 1.9 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain ISK_Channel PF02060.15 GAP84882.1 - 0.13 12.0 0.4 77 3.0 0.0 3.7 1 1 6 7 7 7 0 Slow voltage-gated potassium channel DUF3328 PF11807.8 GAP84883.1 - 7.5e-45 153.4 0.1 9.4e-45 153.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cauli_VI PF01693.16 GAP84884.1 - 1.4e-09 38.1 2.5 3.5e-09 36.8 2.5 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin Pex14_N PF04695.13 GAP84885.1 - 0.028 15.1 1.9 0.028 15.1 1.9 3.0 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 GAP84886.1 - 3.1e-60 203.8 0.0 7.9e-60 202.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84886.1 - 5.4e-36 124.2 0.0 9.3e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 GAP84886.1 - 1.3e-23 82.9 12.7 7.9e-14 51.5 3.4 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 GAP84886.1 - 1.4e-18 66.5 31.5 1.2e-11 44.4 10.7 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 GAP84886.1 - 1.8e-13 50.9 0.9 1.8e-13 50.9 0.9 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 GAP84886.1 - 0.041 13.2 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF3895 PF13034.6 GAP84886.1 - 0.07 13.1 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) Haspin_kinase PF12330.8 GAP84886.1 - 0.1 11.5 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_9 PF13901.6 GAP84886.1 - 5.4 6.9 23.1 1.9 8.4 8.1 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon She9_MDM33 PF05546.11 GAP84887.1 - 4.5e-77 258.3 3.2 6.5e-77 257.8 3.2 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family Macoilin PF09726.9 GAP84887.1 - 0.0039 15.8 1.4 0.0039 15.8 1.4 2.1 2 0 0 2 2 2 1 Macoilin family Cep57_CLD_2 PF14197.6 GAP84887.1 - 0.03 14.4 0.5 0.96 9.6 0.1 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 PsbH PF00737.20 GAP84887.1 - 0.27 11.0 1.0 0.48 10.2 1.0 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein eIF-1a PF01176.19 GAP84888.1 - 4.9e-20 71.1 0.0 6.9e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF2554 PF10829.8 GAP84888.1 - 0.092 13.2 0.1 1.3 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) ALG3 PF05208.13 GAP84889.1 - 8.7e-88 295.1 9.6 1e-87 294.9 9.6 1.0 1 0 0 1 1 1 1 ALG3 protein DUF4408 PF14364.6 GAP84889.1 - 0.094 12.5 0.1 0.094 12.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4408) DUF2723 PF11028.8 GAP84889.1 - 1.2 9.1 9.7 0.38 10.7 6.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2723) DAO PF01266.24 GAP84890.1 - 1.8e-37 129.8 2.5 2.1e-37 129.6 2.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP84890.1 - 1e-05 25.6 0.1 3.6e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAP84890.1 - 9e-05 21.8 0.1 9e-05 21.8 0.1 2.0 2 1 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 GAP84890.1 - 0.0024 17.0 0.3 0.0052 15.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 GAP84890.1 - 0.0031 18.0 0.1 0.017 15.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP84890.1 - 0.0092 15.2 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP84890.1 - 0.056 12.1 0.0 0.086 11.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FYVE_2 PF02318.16 GAP84891.1 - 0.25 11.6 21.8 0.68 10.2 1.6 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger Sar8_2 PF03058.14 GAP84891.1 - 2.7 8.6 16.4 0.78 10.3 0.3 3.4 3 0 0 3 3 3 0 Sar8.2 family Clr2_transil PF16761.5 GAP84892.1 - 2e-14 54.2 3.6 2e-14 54.2 3.6 1.7 2 0 0 2 2 2 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 GAP84892.1 - 7e-10 39.9 1.4 4.4e-09 37.3 0.0 2.6 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 Med3 PF11593.8 GAP84892.1 - 0.23 10.6 9.6 0.43 9.7 9.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal adh_short PF00106.25 GAP84893.1 - 4.5e-16 58.9 2.1 2.2e-15 56.6 0.2 2.3 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.10 GAP84893.1 - 6.1e-07 29.5 0.2 9e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 KR domain Clat_adaptor_s PF01217.20 GAP84894.1 - 1.4e-56 190.4 2.0 1.6e-56 190.2 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-CCHC_2 PF13696.6 GAP84895.1 - 9.5e-09 34.9 24.3 2.1e-07 30.6 12.7 2.5 2 0 0 2 2 2 2 Zinc knuckle eIF3g PF12353.8 GAP84895.1 - 0.0012 19.2 5.0 0.42 11.0 2.0 2.8 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit G Ist1 PF03398.14 GAP84896.1 - 1.6e-60 203.8 1.7 2e-60 203.5 1.7 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ArAE_2_N PF10337.9 GAP84897.1 - 2.5e-21 76.3 5.9 3.6e-15 56.0 0.3 2.4 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 GAP84897.1 - 4.9e-15 55.3 11.6 2.1e-14 53.2 6.3 2.5 3 0 0 3 3 3 2 Aluminium activated malate transporter FUSC_2 PF13515.6 GAP84897.1 - 1.6e-13 50.8 14.0 1.6e-13 50.8 14.0 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 GAP84897.1 - 1.4e-06 27.2 14.4 3.5e-05 22.6 14.4 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 GAP84897.1 - 0.00091 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 adh_short_C2 PF13561.6 GAP84898.1 - 7.5e-48 163.1 0.0 1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP84898.1 - 5.2e-38 130.5 0.0 7e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP84898.1 - 1.7e-09 37.8 0.0 2.3e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 KR domain CENP-B_dimeris PF09026.10 GAP84898.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPV_E1_N PF00524.18 GAP84898.1 - 0.16 12.4 0.4 0.32 11.4 0.4 1.5 1 0 0 1 1 1 0 E1 Protein, N terminal domain DUF4064 PF13273.6 GAP84901.1 - 0.0014 18.9 0.1 0.0016 18.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) RTA1 PF04479.13 GAP84901.1 - 0.019 14.6 0.5 0.021 14.4 0.5 1.0 1 0 0 1 1 1 0 RTA1 like protein Trp_oprn_chp PF09534.10 GAP84901.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sod_Cu PF00080.20 GAP84902.1 - 3.1e-09 37.2 0.0 5.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Aminotran_5 PF00266.19 GAP84904.1 - 1.4e-19 70.3 0.0 2.4e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Zn_clus PF00172.18 GAP84905.1 - 3.7e-06 27.0 7.8 5.2e-06 26.5 7.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF202 PF02656.15 GAP84906.1 - 0.00021 21.7 2.0 0.00021 21.7 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) zf-C2H2 PF00096.26 GAP84907.1 - 6.9e-06 26.2 22.6 0.00075 19.8 0.5 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP84907.1 - 0.0023 18.6 0.8 0.0023 18.6 0.8 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAP84907.1 - 0.024 14.7 0.4 0.024 14.7 0.4 2.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAP84907.1 - 0.45 10.9 5.3 0.34 11.2 2.8 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 GAP84907.1 - 6.5 7.5 10.6 3.4 8.3 2.2 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain TRP PF06011.12 GAP84908.1 - 4.8e-133 444.0 17.3 5.8e-133 443.7 17.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 GAP84908.1 - 8.7e-39 133.1 2.0 1.5e-38 132.3 2.0 1.4 1 0 0 1 1 1 1 ML-like domain Proteasome PF00227.26 GAP84909.1 - 8.3e-47 159.1 0.1 1e-46 158.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M22 PF00814.25 GAP84910.1 - 8.8e-45 153.5 0.4 8e-15 55.3 0.2 4.1 4 0 0 4 4 4 4 Glycoprotease family Tubulin PF00091.25 GAP84911.1 - 2.8e-54 184.3 0.0 4.1e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAP84911.1 - 2.5e-44 150.5 0.0 3.9e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 GAP84911.1 - 0.00052 19.7 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Peptidase_S8 PF00082.22 GAP84912.1 - 2.6e-29 102.4 8.1 3.8e-29 101.9 8.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAP84912.1 - 3.4e-06 27.6 0.0 7.7e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF1989 PF09347.10 GAP84913.1 - 2.2e-58 196.6 0.0 2.9e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Terpene_synth_C PF03936.16 GAP84914.1 - 1.1e-08 34.7 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain BicD PF09730.9 GAP84914.1 - 0.1 11.0 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Med16 PF11635.8 GAP84915.1 - 1.6e-71 241.3 0.1 2.1e-71 240.9 0.1 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 SIR2 PF02146.17 GAP84916.1 - 1.9e-28 99.6 0.0 8.9e-28 97.4 0.0 1.9 1 1 0 1 1 1 1 Sir2 family SNF2_N PF00176.23 GAP84917.1 - 9.1e-58 195.6 0.1 1.5e-57 194.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 GAP84917.1 - 5.4e-24 83.9 2.6 5.5e-16 58.2 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 GAP84917.1 - 3.7e-18 65.9 0.0 1e-17 64.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 GAP84917.1 - 3.9e-10 40.0 2.4 4.8e-10 39.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 GAP84917.1 - 3.4e-08 33.0 0.6 9.4e-08 31.6 0.0 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 GAP84917.1 - 9.2e-07 29.0 0.0 4.5e-06 26.8 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 GAP84917.1 - 4.1e-06 27.1 1.5 4.1e-06 27.1 1.5 5.4 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 GAP84917.1 - 0.0021 18.1 0.8 0.021 14.8 0.0 3.0 2 1 0 2 2 2 1 SLIDE AAA_22 PF13401.6 GAP84917.1 - 0.12 12.6 0.0 0.57 10.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain FF PF01846.19 GAP84918.1 - 2.6e-48 162.0 13.7 7.5e-14 51.6 0.2 7.2 6 1 0 6 6 6 6 FF domain WW PF00397.26 GAP84918.1 - 5.8e-18 64.7 17.2 7.8e-10 38.7 3.1 2.9 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 GAP84918.1 - 0.00021 21.9 8.3 2 9.1 0.0 5.1 4 1 1 5 5 5 2 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 GAP84918.1 - 0.95 9.8 6.9 5.6 7.3 0.2 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Trs65 PF12735.7 GAP84919.1 - 2e-111 372.4 0.2 2.7e-111 372.0 0.2 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Guanylate_cyc PF00211.20 GAP84920.1 - 0.018 14.7 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain L6_membrane PF05805.12 GAP84922.1 - 1 8.9 5.9 0.18 11.3 0.6 2.1 2 0 0 2 2 2 0 L6 membrane protein Filament PF00038.21 GAP84923.1 - 0.0056 16.3 10.7 0.0056 16.3 10.7 6.1 5 1 1 6 6 6 4 Intermediate filament protein RTBV_P12 PF06361.11 GAP84923.1 - 0.31 11.5 1.1 12 6.4 0.0 3.5 2 1 1 3 3 3 0 Rice tungro bacilliform virus P12 protein MtrG PF04210.13 GAP84923.1 - 0.31 10.9 1.3 31 4.5 0.0 3.2 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Glyco_hydro_88 PF07470.13 GAP84924.1 - 1.1e-42 146.3 0.5 1.5e-42 145.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 NAD_binding_4 PF07993.12 GAP84926.1 - 6e-36 123.9 0.0 9.2e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAP84926.1 - 1.1e-23 83.6 1.1 1.7e-22 79.6 1.1 2.4 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAP84926.1 - 3.1e-10 40.2 0.1 1.9e-09 37.8 0.0 2.4 3 0 0 3 3 3 1 Phosphopantetheine attachment site Epimerase PF01370.21 GAP84926.1 - 0.00019 21.0 0.0 0.0013 18.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAP84926.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 KR domain Methyltransf_2 PF00891.18 GAP84927.1 - 3.2e-24 85.4 0.0 4.5e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAP84927.1 - 0.00014 22.5 0.0 0.00075 20.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP84927.1 - 0.0019 18.9 0.0 0.0038 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP84927.1 - 0.0024 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GAP84927.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Lyase_aromatic PF00221.19 GAP84928.1 - 1e-150 502.5 5.5 1.5e-150 501.9 5.5 1.2 1 0 0 1 1 1 1 Aromatic amino acid lyase FAD_binding_3 PF01494.19 GAP84929.1 - 9.9e-47 159.9 0.0 1.3e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP84929.1 - 3.1e-06 27.0 0.3 9.5e-06 25.4 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP84929.1 - 2.2e-05 24.6 0.2 4.9e-05 23.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAP84929.1 - 0.00011 21.4 0.0 0.006 15.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAP84929.1 - 0.00018 20.4 0.1 0.00033 19.5 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAP84929.1 - 0.0002 20.7 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP84929.1 - 0.0016 17.7 0.0 0.0031 16.8 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP84929.1 - 0.0036 16.6 0.0 0.0061 15.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.16 GAP84929.1 - 0.0047 16.6 0.1 0.0081 15.8 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 GAP84929.1 - 0.015 15.8 0.1 0.17 12.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAP84929.1 - 0.03 13.7 0.1 0.073 12.4 0.2 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 GAP84929.1 - 0.03 14.7 0.0 0.069 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 GAP84929.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 GAP84929.1 - 0.074 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 GAP84929.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_23 PF13489.6 GAP84930.1 - 1e-11 45.0 0.0 2e-11 44.0 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP84930.1 - 1.2e-07 32.3 0.0 1e-06 29.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP84930.1 - 8.6e-06 26.4 0.0 2.1e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP84930.1 - 6.6e-05 23.5 0.0 0.00018 22.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP84930.1 - 0.0032 17.3 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP84930.1 - 0.012 15.0 0.0 0.053 12.8 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 GAP84930.1 - 0.023 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 GAP84930.1 - 0.055 13.0 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 GAP84932.1 - 3.8e-74 250.1 0.0 4.3e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3445 PF11927.8 GAP84934.1 - 5.2e-77 258.5 0.0 6.4e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) RsbU_N PF08673.10 GAP84934.1 - 0.085 13.0 0.0 2.1 8.5 0.1 2.4 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF5397 PF17375.2 GAP84934.1 - 0.13 12.0 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5397) Gram_pos_anchor PF00746.21 GAP84934.1 - 0.18 11.8 0.6 0.33 10.9 0.6 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF846 PF05832.12 GAP84935.1 - 2.7e-42 144.1 4.1 3.2e-42 143.9 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Dpy19 PF10034.9 GAP84935.1 - 0.086 11.0 0.0 0.079 11.2 0.0 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF4191 PF13829.6 GAP84935.1 - 0.64 9.3 1.8 0.77 9.1 0.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF4448 PF14610.6 GAP84936.1 - 0.067 13.0 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SelP_N PF04592.14 GAP84936.1 - 0.23 10.8 6.2 0.47 9.8 6.2 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SKG6 PF08693.10 GAP84936.1 - 0.27 10.7 4.1 0.21 11.0 1.9 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain MGC-24 PF05283.11 GAP84936.1 - 9.7 6.6 10.4 0.75 10.2 3.3 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF726 PF05277.12 GAP84937.1 - 3.3e-124 414.3 1.0 4.9e-124 413.7 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) p450 PF00067.22 GAP84938.1 - 2.7e-68 230.8 0.0 3.6e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fcf1 PF04900.12 GAP84939.1 - 8.6e-24 83.8 0.0 1.5e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Fcf1 SpoIIE PF07228.12 GAP84940.1 - 3.2e-06 27.2 0.0 2.8e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 GAP84940.1 - 0.00096 18.9 0.1 0.37 10.4 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 GAP84940.1 - 0.0027 17.4 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PH PF00169.29 GAP84941.1 - 2.8e-07 31.0 0.1 2.7e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 GAP84941.1 - 0.00089 19.6 0.0 0.0058 17.0 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Lipase_GDSL_2 PF13472.6 GAP84942.1 - 5.3e-18 66.0 0.0 6.8e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BLM10_N PF16547.5 GAP84942.1 - 0.014 15.7 0.1 0.031 14.6 0.1 1.5 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Lipase_GDSL PF00657.22 GAP84942.1 - 0.084 12.8 0.0 0.89 9.5 0.0 2.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase PCI PF01399.27 GAP84943.1 - 2.4e-09 37.7 0.0 1.5e-08 35.1 0.0 2.2 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.9 GAP84943.1 - 0.013 15.2 0.1 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Rx_N PF18052.1 GAP84943.1 - 0.84 9.9 4.5 4 7.8 0.9 3.3 3 1 1 4 4 4 0 Rx N-terminal domain HSCB_C PF07743.13 GAP84944.1 - 8.4e-18 64.6 1.2 1.6e-17 63.7 0.3 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 GAP84944.1 - 0.00083 19.4 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain F-box-like PF12937.7 GAP84945.1 - 0.044 13.7 0.2 0.16 11.8 0.2 2.1 1 1 0 1 1 1 0 F-box-like LRR_4 PF12799.7 GAP84945.1 - 3.3 8.3 7.7 1.6 9.2 0.8 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAP84945.1 - 5.4 6.9 6.9 7 6.5 1.9 2.6 2 0 0 2 2 2 0 Leucine rich repeat SNF2_N PF00176.23 GAP84946.1 - 9.4e-38 129.8 0.0 3.7e-33 114.7 0.0 2.4 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP84946.1 - 3.2e-06 27.4 0.1 8.2e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP84946.1 - 2.9e-05 24.2 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Aldo_ket_red PF00248.21 GAP84948.1 - 1.3e-57 195.3 0.0 1.4e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dus PF01207.17 GAP84949.1 - 5.3e-25 88.2 0.0 2.6e-21 76.0 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Pkinase PF00069.25 GAP84950.1 - 3.5e-67 226.6 0.0 4.3e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84950.1 - 6.9e-32 110.7 0.0 9.4e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAP84950.1 - 0.00028 21.5 1.1 0.00028 21.5 1.1 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 GAP84950.1 - 0.0072 15.3 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 GAP84950.1 - 0.083 12.5 0.0 0.94 9.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Oest_recep PF02159.15 GAP84950.1 - 0.16 12.5 1.6 0.28 11.7 1.6 1.4 1 0 0 1 1 1 0 Oestrogen receptor CDH-cyt PF16010.5 GAP84951.1 - 2.7e-20 72.8 1.4 2.7e-20 72.8 1.4 1.6 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 GAP84951.1 - 7.3e-07 29.4 0.1 1.6e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 GAP84951.1 - 0.041 13.7 9.1 0.045 13.5 4.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) RAP1 PF07218.11 GAP84951.1 - 5.9 5.0 9.8 8.1 4.6 9.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) WD40 PF00400.32 GAP84952.1 - 3e-37 126.0 19.1 1.4e-07 32.0 0.1 7.9 7 1 0 7 7 7 5 WD domain, G-beta repeat PRP4 PF08799.11 GAP84952.1 - 7.1e-15 54.3 4.4 7.1e-15 54.3 4.4 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 GAP84952.1 - 3.6e-13 49.6 2.5 0.017 15.4 0.0 5.7 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAP84952.1 - 0.0042 16.5 0.0 1.2 8.3 0.0 3.0 3 0 0 3 3 3 1 WD40-like domain eIF2A PF08662.11 GAP84952.1 - 0.0047 16.8 0.0 0.072 13.0 0.0 2.7 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 GAP84952.1 - 0.0095 15.3 0.0 0.44 9.8 0.0 2.3 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 GAP84952.1 - 0.24 10.3 0.0 23 3.8 0.0 3.3 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cyclin_N PF00134.23 GAP84953.1 - 1.1e-10 41.4 0.1 1.9e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 GAP84953.1 - 0.041 13.9 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat ATP_sub_h PF10775.9 GAP84954.1 - 2.5e-26 91.4 1.3 3.7e-26 90.9 1.3 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h Pkinase PF00069.25 GAP84955.1 - 9e-69 231.8 0.0 1.2e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP84955.1 - 1.9e-31 109.3 0.0 2.8e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAP84955.1 - 1.4e-13 51.3 1.3 5e-13 49.5 0.4 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 GAP84955.1 - 4.3e-10 39.4 0.1 1.8e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 GAP84955.1 - 1.1e-07 32.1 0.0 1.2e-05 25.6 0.0 2.7 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 GAP84955.1 - 0.00094 18.2 0.2 0.0021 17.1 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAP84955.1 - 0.0098 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAP84955.1 - 0.04 13.5 0.3 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 GAP84955.1 - 0.057 13.0 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Adeno_E3_15_3 PF03307.14 GAP84955.1 - 0.095 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region APH PF01636.23 GAP84955.1 - 0.11 12.4 0.2 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GFA PF04828.14 GAP84957.1 - 1.9e-15 56.9 0.2 2.5e-15 56.6 0.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 GAP84957.1 - 0.0072 16.0 1.8 0.0072 16.0 1.8 2.4 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 GAP84957.1 - 8 6.5 9.3 1 9.3 0.3 2.4 2 0 0 2 2 2 0 Nudix N-terminal Peptidase_C98 PF15499.6 GAP84959.1 - 0.23 10.9 1.7 0.91 8.9 0.0 2.5 2 1 1 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF1993 PF09351.10 GAP84959.1 - 2.8 8.1 9.3 0.19 11.9 0.4 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1993) CorA PF01544.18 GAP84959.1 - 4.7 6.4 8.6 0.13 11.5 1.2 2.2 3 1 0 3 3 3 0 CorA-like Mg2+ transporter protein SUZ PF12752.7 GAP84960.1 - 7.5e-05 23.4 5.0 7.5e-05 23.4 5.0 3.3 3 2 0 3 3 3 1 SUZ domain Nexin_C PF08628.12 GAP84960.1 - 0.14 12.7 2.7 2.8 8.6 0.1 2.2 2 0 0 2 2 2 0 Sorting nexin C terminal Fe_hyd_lg_C PF02906.14 GAP84961.1 - 7e-53 179.8 0.0 1.3e-52 178.9 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SH3_9 PF14604.6 GAP84963.1 - 1.1e-29 102.0 3.9 1.5e-14 53.6 0.5 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 GAP84963.1 - 2.3e-26 91.1 3.3 7.5e-13 47.9 0.4 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 GAP84963.1 - 1.2e-15 56.9 0.0 1.3e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 GAP84963.1 - 1.7e-13 50.4 0.0 3.4e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Glutaredoxin PF00462.24 GAP84964.1 - 2.6e-16 59.6 0.0 2.9e-15 56.2 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 GAP84964.1 - 3.1e-13 49.6 0.0 6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 GAP84964.1 - 0.0051 16.8 0.4 0.024 14.7 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.11 GAP84964.1 - 0.0058 16.6 0.0 0.04 13.9 0.0 2.2 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 GAP84964.1 - 0.021 15.1 0.0 1.3 9.4 0.0 2.5 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 GAP84964.1 - 0.046 14.2 0.1 0.9 10.0 0.0 2.8 1 1 1 2 2 2 0 Thioredoxin-like domain SR-25 PF10500.9 GAP84965.1 - 5.4 6.6 9.8 6 6.4 9.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM199X PF15814.5 GAP84965.1 - 6.4 5.7 10.5 7.4 5.5 10.5 1.0 1 0 0 1 1 1 0 Protein family FAM199X Ion_trans PF00520.31 GAP84966.1 - 8.6e-126 418.1 83.8 5.5e-42 143.7 6.5 4.9 4 1 0 4 4 4 4 Ion transport protein EF-hand_7 PF13499.6 GAP84966.1 - 0.12 12.8 0.0 0.39 11.2 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair GPHH PF16905.5 GAP84966.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated EamA PF00892.20 GAP84967.1 - 9.9e-05 22.5 8.8 0.0002 21.5 3.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family PP2C_2 PF13672.6 GAP84967.1 - 0.092 12.4 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C TMEM234 PF10639.9 GAP84967.1 - 0.12 12.4 1.3 0.19 11.8 1.3 1.2 1 0 0 1 1 1 0 Putative transmembrane family 234 DUF2754 PF10953.8 GAP84967.1 - 0.23 11.7 1.9 3.2 8.1 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2754) TFIIA_gamma_N PF02268.16 GAP84968.1 - 9.8e-25 86.3 0.2 1.4e-24 85.9 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 GAP84968.1 - 2.5e-22 78.8 1.3 4e-22 78.1 1.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DSBA PF01323.20 GAP84969.1 - 8.9e-37 126.7 0.0 1e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 GAP84969.1 - 0.0051 16.8 0.1 0.41 10.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.6 GAP84969.1 - 0.015 15.5 0.0 0.066 13.4 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin GRAS PF03514.14 GAP84969.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 GRAS domain family Asp PF00026.23 GAP84970.1 - 4.6e-10 39.4 0.0 4.3e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic aspartyl protease HAD PF12710.7 GAP84971.1 - 0.00083 19.8 0.1 0.0026 18.2 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Comm PF15957.5 GAP84972.1 - 0.029 14.7 0.0 0.057 13.8 0.0 1.5 1 0 0 1 1 1 0 Commissureless Shisa PF13908.6 GAP84972.1 - 0.19 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Sulfotransfer_4 PF17784.1 GAP84973.1 - 7e-62 209.1 0.0 9.3e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain OppC_N PF12911.7 GAP84974.1 - 2.2 8.3 5.2 1.8 8.6 0.1 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C GMC_oxred_N PF00732.19 GAP84975.1 - 1.5e-63 214.9 0.0 2.4e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP84975.1 - 3.2e-30 105.5 0.0 5.7e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAP84975.1 - 0.00027 20.1 0.3 0.00042 19.5 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAP84975.1 - 0.009 15.3 0.7 0.021 14.1 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 GAP84975.1 - 0.014 14.5 0.3 3.6 6.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.16 GAP84976.1 - 7.3e-23 81.0 38.5 7.3e-23 81.0 38.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAP84976.1 - 0.0014 17.6 7.4 0.0014 17.6 7.4 2.2 1 1 0 2 2 2 1 MFS_1 like family zf-C2H2_3rep PF18868.1 GAP84977.1 - 0.012 16.3 1.2 0.012 16.3 1.2 2.1 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 GAP84977.1 - 0.014 15.7 2.3 0.014 15.7 2.3 3.1 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 GAP84977.1 - 0.03 15.1 1.6 0.03 15.1 1.6 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAP84977.1 - 0.91 9.9 8.1 1.7 9.0 2.0 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TPR_10 PF13374.6 GAP84978.1 - 4.2e-36 121.8 0.0 4.3e-11 42.3 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAP84978.1 - 1.7e-26 92.3 0.0 5.4e-10 39.4 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 GAP84978.1 - 8e-15 54.7 0.0 1.4e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.22 GAP84978.1 - 2.1e-06 27.2 0.0 3.1e-05 23.3 0.0 2.4 2 1 0 2 2 2 1 NB-ARC domain TPR_2 PF07719.17 GAP84978.1 - 2.5e-06 27.2 0.0 0.65 10.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP84978.1 - 2.8e-06 27.0 0.1 0.16 12.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAP84978.1 - 0.0018 18.0 0.0 2.6 8.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAP84978.1 - 0.0055 17.3 0.0 4.7 7.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAP84978.1 - 0.0058 17.1 1.7 2.7 8.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.12 GAP84978.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TPR_14 PF13428.6 GAP84978.1 - 0.017 15.9 0.2 37 5.5 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 GAP84978.1 - 0.045 14.1 1.0 0.15 12.4 0.2 2.3 2 1 0 2 2 2 0 AAA ATPase domain TPR_19 PF14559.6 GAP84978.1 - 0.1 13.1 0.0 25 5.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 GAP84979.1 - 5.3e-147 490.4 6.2 6e-147 490.2 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 GAP84979.1 - 0.067 13.7 0.1 0.28 11.7 0.0 2.1 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch FtsA PF14450.6 GAP84979.1 - 0.56 10.7 1.9 1 9.8 1.9 1.8 1 1 0 1 1 1 0 Cell division protein FtsA zf-H2C2 PF09337.10 GAP84980.1 - 1.2e-14 54.2 0.5 2.6e-14 53.1 0.5 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 GAP84980.1 - 8e-12 45.1 0.1 8e-12 45.1 0.1 2.6 3 0 0 3 3 3 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 GAP84980.1 - 0.006 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family EF-G-binding_N PF07299.11 GAP84980.1 - 0.46 11.0 2.2 0.88 10.1 2.2 1.3 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Presenilin PF01080.17 GAP84980.1 - 7 5.3 8.7 8.9 5.0 1.3 2.1 2 0 0 2 2 2 0 Presenilin CPSF100_C PF13299.6 GAP84980.1 - 9.4 6.4 9.0 4.6 7.4 1.5 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal MFS_1 PF07690.16 GAP84981.1 - 2.9e-14 52.8 19.8 2.9e-14 52.8 19.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 GAP84981.1 - 0.038 14.3 0.3 0.038 14.3 0.3 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF1772) Ribosomal_S2 PF00318.20 GAP84982.1 - 5.6e-64 215.3 0.1 1.1e-62 211.1 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 Med3 PF11593.8 GAP84982.1 - 0.00031 20.1 3.4 0.00051 19.3 3.4 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal PGA_cap PF09587.10 GAP84982.1 - 0.13 11.7 0.7 0.35 10.3 0.1 1.9 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap CBS PF00571.28 GAP84983.1 - 1.4e-33 115.1 5.5 1.1e-08 35.4 0.0 5.5 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 GAP84983.1 - 7e-11 41.9 0.2 1.9e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 PB1 domain FAD_binding_3 PF01494.19 GAP84984.1 - 4.6e-33 114.9 0.0 7.1e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP84984.1 - 4.8e-09 35.9 2.5 0.00071 18.9 0.1 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP84984.1 - 2e-08 33.9 0.0 9.6e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP84984.1 - 2e-08 33.3 0.5 6.4e-05 21.8 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.24 GAP84984.1 - 3.3e-08 33.3 0.6 0.00042 19.7 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 GAP84984.1 - 3.1e-07 29.8 0.1 8.9e-07 28.3 0.1 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 GAP84984.1 - 9.9e-06 25.4 1.4 0.0062 16.1 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAP84984.1 - 8.2e-05 23.1 2.6 0.036 14.6 0.3 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP84984.1 - 0.00012 22.3 0.3 0.00029 21.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAP84984.1 - 0.00015 21.0 0.4 0.00015 21.0 0.4 2.0 3 0 0 3 3 3 1 FAD binding domain Trp_halogenase PF04820.14 GAP84984.1 - 0.00025 20.1 0.9 0.45 9.3 0.0 2.9 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 GAP84984.1 - 0.0022 18.0 1.1 0.095 12.7 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAP84984.1 - 0.0029 16.9 0.0 0.0072 15.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 GAP84984.1 - 0.0038 16.4 1.0 0.052 12.6 0.3 2.2 2 1 0 2 2 2 1 Glucose inhibited division protein A DUF1382 PF07131.11 GAP84984.1 - 0.029 14.4 0.3 1.1 9.3 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1382) FAD_oxidored PF12831.7 GAP84984.1 - 0.077 12.3 1.8 0.13 11.6 0.9 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase HET PF06985.11 GAP84985.1 - 9.7e-26 90.9 0.0 2.5e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 GAP84986.1 - 1e-22 80.9 0.0 1.6e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP84986.1 - 1.2e-07 31.7 1.4 1.7e-05 24.6 0.3 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP84986.1 - 2.6e-05 23.6 0.1 0.00041 19.7 0.1 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP84986.1 - 3.7e-05 23.0 0.7 0.00015 21.0 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 GAP84986.1 - 7.9e-05 21.9 0.0 0.00016 20.9 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAP84986.1 - 9.6e-05 22.5 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAP84986.1 - 0.0017 18.9 0.0 0.036 14.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP84986.1 - 0.0025 17.1 0.1 0.16 11.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP84986.1 - 0.0051 15.6 0.1 0.57 8.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 GAP84986.1 - 0.031 13.3 0.2 0.052 12.6 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF2439 PF10382.9 GAP84986.1 - 0.032 14.5 0.2 0.074 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) SE PF08491.10 GAP84986.1 - 0.047 12.7 0.0 3.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_10 PF13460.6 GAP84987.1 - 5.2e-32 111.2 0.0 6.1e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP84987.1 - 5.8e-06 25.9 0.0 6.8e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAP84987.1 - 7.2e-05 22.4 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 GAP84987.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain Mid2 PF04478.12 GAP84988.1 - 4.1e-05 23.4 0.0 9.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor AA_permease PF00324.21 GAP84989.1 - 2.2e-126 422.3 40.4 2.6e-126 422.0 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP84989.1 - 5.1e-29 101.4 49.0 6.1e-29 101.1 49.0 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 GAP84991.1 - 4.9e-13 48.7 0.0 6.9e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP84991.1 - 4.1e-10 39.6 7.9 7.6e-10 38.8 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 GAP84992.1 - 1.5e-15 57.6 0.8 3.1e-15 56.5 0.3 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP84992.1 - 6.6e-07 28.8 0.2 2.5e-06 26.9 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 CDC45 PF02724.14 GAP84993.1 - 0.2 9.9 3.3 0.28 9.4 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_ligase_A_M PF01068.21 GAP84994.1 - 7.9e-48 162.8 0.0 2.4e-45 154.7 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAP84994.1 - 1.2e-34 120.1 0.0 3e-34 118.8 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 GAP84994.1 - 2.4e-19 69.8 0.0 1.5e-12 47.9 0.0 3.3 4 0 0 4 4 4 2 ATP dependent DNA ligase C terminal region NuDC PF16273.5 GAP84994.1 - 0.35 11.4 0.1 0.35 11.4 0.1 3.3 3 0 0 3 3 3 0 Nuclear distribution C domain NOA36 PF06524.12 GAP84994.1 - 2.7 7.2 7.6 0.81 8.9 0.2 2.4 2 0 0 2 2 2 0 NOA36 protein Aldose_epim PF01263.20 GAP84995.1 - 2.6e-57 194.5 0.0 3.2e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3767 PF12597.8 GAP84997.1 - 7.3e-37 125.2 0.2 7.3e-37 125.2 0.2 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) SARAF PF06682.12 GAP84997.1 - 0.031 13.9 0.5 0.04 13.6 0.5 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DivIC PF04977.15 GAP84997.1 - 0.16 11.8 4.7 0.21 11.4 4.7 1.1 1 0 0 1 1 1 0 Septum formation initiator 5TM-5TMR_LYT PF07694.12 GAP84997.1 - 0.2 11.2 0.7 0.27 10.7 0.7 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF1744 PF08490.12 GAP84998.1 - 1.3e-158 527.8 0.1 1.9e-158 527.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 GAP84998.1 - 1.2e-78 264.6 0.0 2.5e-78 263.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 GAP84998.1 - 3.2e-16 59.1 0.2 1.4e-13 50.4 0.1 3.0 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 GAP84998.1 - 6e-08 32.6 0.2 2.8e-07 30.4 0.2 2.0 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 GAP84998.1 - 5.1e-05 23.3 0.0 0.0002 21.4 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily Ank_2 PF12796.7 GAP84999.1 - 8.7e-17 61.5 0.0 3.8e-10 40.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAP84999.1 - 6.1e-13 48.6 0.0 0.019 15.4 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 GAP84999.1 - 1.1e-12 48.2 0.0 1.3e-05 25.6 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP84999.1 - 6.2e-09 36.0 0.0 0.00061 20.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP84999.1 - 1.5e-08 34.2 0.0 0.56 10.9 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat vWA-TerF-like PF10138.9 GAP84999.1 - 0.0004 20.6 0.0 0.00098 19.3 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus Carbam_trans_N PF02543.15 GAP84999.1 - 0.1 12.2 0.0 1 8.9 0.0 2.0 1 1 1 2 2 2 0 Carbamoyltransferase N-terminus FAD_binding_4 PF01565.23 GAP85000.1 - 2.3e-26 92.2 0.1 1.6e-25 89.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAP85000.1 - 2.1e-10 40.5 0.3 5e-10 39.3 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 GAP85001.1 - 8e-29 100.5 0.6 1.9e-28 99.3 0.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP85001.1 - 1.8e-14 53.9 0.4 3.4e-14 53.0 0.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP85001.1 - 2.3e-10 40.7 0.7 3e-10 40.3 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP85001.1 - 0.0009 18.8 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAP85001.1 - 0.054 12.6 0.3 0.068 12.3 0.3 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peripla_BP_1 PF00532.21 GAP85001.1 - 0.083 12.3 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Zn_clus PF00172.18 GAP85003.1 - 2.9e-07 30.5 10.1 5e-07 29.7 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_45 PF02015.16 GAP85004.1 - 3e-85 285.4 16.4 3.5e-85 285.2 16.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 ADH_N PF08240.12 GAP85005.1 - 5.8e-26 90.5 5.1 9.5e-26 89.8 5.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP85005.1 - 2.8e-14 53.2 0.0 6.4e-14 52.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAP85005.1 - 0.0025 17.1 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAP85005.1 - 0.0043 16.4 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GPP34 PF05719.11 GAP85006.1 - 1.2e-68 231.2 0.0 1.5e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) RPAP1_C PF08620.10 GAP85007.1 - 1.1e-11 44.6 0.0 2.4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 GAP85007.1 - 5.6e-07 29.2 1.7 1.1e-06 28.3 1.7 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal SPX PF03105.19 GAP85007.1 - 0.052 13.5 0.7 0.059 13.3 0.7 1.2 1 0 0 1 1 1 0 SPX domain LPD26 PF18842.1 GAP85007.1 - 0.11 12.4 0.1 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein associated domain 26 HUN PF08729.10 GAP85008.1 - 3e-07 30.3 0.4 7e-07 29.1 0.4 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain TFIIA PF03153.13 GAP85008.1 - 1.9 8.4 40.0 0.13 12.2 1.7 2.3 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 GAP85009.1 - 2.3e-32 112.1 0.1 3.2e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP85009.1 - 1.3e-27 96.9 1.2 3.6e-27 95.4 1.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP85009.1 - 4.2e-06 26.8 0.3 2.9e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 GAP85009.1 - 0.0043 16.5 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DEC-1_N PF04625.13 GAP85010.1 - 0.024 13.6 2.1 0.032 13.3 2.1 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SURF6 PF04935.12 GAP85011.1 - 3.9e-51 173.7 44.7 3.9e-51 173.7 44.7 4.3 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 GAP85011.1 - 2.1e-14 53.9 0.6 2.1e-14 53.9 0.6 7.9 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 Peptidase_S51 PF03575.17 GAP85012.1 - 9.4e-15 54.8 0.0 1.1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 FMN_dh PF01070.18 GAP85014.1 - 2.3e-85 286.7 0.1 5.7e-48 163.7 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 GAP85014.1 - 0.00082 18.5 0.7 0.003 16.6 0.7 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 GAP85014.1 - 0.00096 18.6 0.1 0.0049 16.3 0.1 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 GAP85014.1 - 0.041 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase ThiG PF05690.14 GAP85014.1 - 0.044 13.1 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Beta-lactamase PF00144.24 GAP85015.1 - 9.7e-50 169.7 0.1 1.4e-49 169.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 GAP85015.1 - 2.8e-14 53.4 0.0 1e-13 51.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) PilO PF04350.13 GAP85015.1 - 0.11 12.7 0.0 1.3 9.2 0.0 2.4 3 0 0 3 3 3 0 Pilus assembly protein, PilO Patatin PF01734.22 GAP85016.1 - 9.3e-24 84.7 0.0 2.5e-23 83.3 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 GAP85016.1 - 8.9e-13 48.0 0.4 1.9e-08 33.8 0.1 2.5 1 1 1 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 GAP85016.1 - 1.6e-06 28.6 0.1 6.3e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Phage_portal PF04860.12 GAP85016.1 - 0.023 13.9 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Phage portal protein AAA_33 PF13671.6 GAP85016.1 - 0.05 13.8 0.5 8.8 6.5 0.0 3.7 4 0 0 4 4 4 0 AAA domain Abhydrolase_6 PF12697.7 GAP85017.1 - 1.4e-10 42.2 0.2 1.7e-10 41.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank PF00023.30 GAP85018.1 - 4.6e-16 58.5 0.0 4.6e-06 26.8 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 GAP85018.1 - 4.8e-16 59.1 0.0 5.7e-07 30.0 0.0 3.8 3 1 1 4 4 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP85018.1 - 1.3e-15 57.3 0.2 4.2e-07 30.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAP85018.1 - 5e-15 55.7 0.3 6e-06 26.7 0.0 4.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP85018.1 - 8.6e-12 44.2 0.0 0.0002 21.5 0.0 5.5 5 0 0 5 5 4 2 Ankyrin repeat NACHT PF05729.12 GAP85018.1 - 7.5e-10 39.0 0.0 1.4e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP85018.1 - 2.6e-07 31.2 0.1 1.8e-06 28.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP85018.1 - 0.0001 22.6 0.0 0.0013 19.0 0.0 2.9 4 0 0 4 4 2 1 AAA domain KAP_NTPase PF07693.14 GAP85018.1 - 0.00064 19.1 0.2 0.045 13.0 0.0 2.2 1 1 1 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.22 GAP85018.1 - 0.0036 16.5 0.0 0.02 14.1 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.6 GAP85018.1 - 0.0075 16.0 0.0 0.43 10.4 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain PGAP1 PF07819.13 GAP85018.1 - 0.019 14.7 0.0 0.054 13.2 0.0 1.7 2 0 0 2 2 1 0 PGAP1-like protein AAA_30 PF13604.6 GAP85018.1 - 0.022 14.5 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAP85018.1 - 0.029 14.4 0.0 9.6 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 GAP85018.1 - 0.047 14.1 0.0 0.18 12.3 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Abhydrolase_6 PF12697.7 GAP85018.1 - 0.049 14.2 0.9 0.19 12.3 0.0 2.5 2 1 0 2 2 1 0 Alpha/beta hydrolase family HTH_Crp_2 PF13545.6 GAP85018.1 - 0.082 12.9 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Ploopntkinase3 PF18751.1 GAP85018.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 GAP85018.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase HTH_38 PF13936.6 GAP85018.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_18 PF13238.6 GAP85018.1 - 0.11 13.0 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 GAP85018.1 - 0.12 12.1 0.1 0.3 10.8 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF676 PF05057.14 GAP85018.1 - 0.12 11.8 0.0 0.88 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 GAP85018.1 - 0.14 11.4 0.0 0.76 9.0 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SseC PF04888.12 GAP85019.1 - 0.15 11.7 3.5 0.59 9.7 3.5 1.8 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Methyltransf_2 PF00891.18 GAP85020.1 - 0.0057 16.0 0.1 0.014 14.7 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation PF08100.11 GAP85020.1 - 0.045 13.8 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Dimerisation domain HTH_IclR PF09339.10 GAP85020.1 - 0.16 11.8 1.1 1.2 8.9 0.0 2.6 2 1 0 2 2 2 0 IclR helix-turn-helix domain MGC-24 PF05283.11 GAP85021.1 - 0.75 10.2 3.7 1.1 9.7 3.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MFS_1 PF07690.16 GAP85022.1 - 3.7e-10 39.3 47.0 1.4e-09 37.3 37.2 3.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2970 PF11174.8 GAP85023.1 - 0.031 14.1 0.4 0.06 13.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Oxidored_q2 PF00420.24 GAP85023.1 - 0.037 13.7 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Plasmodium_HRP PF05403.11 GAP85024.1 - 0.013 15.3 0.1 0.016 15.0 0.1 1.1 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) ABC_membrane PF00664.23 GAP85025.1 - 1.8e-41 142.6 10.8 2.3e-41 142.3 10.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAP85025.1 - 2.6e-32 112.2 0.0 4.5e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 GAP85025.1 - 4.3e-06 26.3 0.0 0.0026 17.2 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAP85025.1 - 0.00055 20.4 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 GAP85025.1 - 0.00086 19.2 0.0 0.027 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 GAP85025.1 - 0.002 18.2 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAP85025.1 - 0.0029 17.9 0.0 0.042 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAP85025.1 - 0.0066 16.9 0.0 0.028 14.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 GAP85025.1 - 0.0087 16.1 0.0 0.074 13.1 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 GAP85025.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 GAP85025.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 GAP85025.1 - 0.015 15.0 0.1 0.044 13.5 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAP85025.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 GAP85025.1 - 0.033 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 GAP85025.1 - 0.033 14.7 0.0 0.063 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAP85025.1 - 0.041 14.1 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAP85025.1 - 0.071 13.7 0.0 0.24 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 GAP85025.1 - 0.091 13.0 0.3 1.2 9.4 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 GAP85025.1 - 0.091 12.3 0.1 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAP85025.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_10 PF12846.7 GAP85025.1 - 0.14 11.0 0.1 0.35 9.7 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.12 GAP85025.1 - 0.15 11.3 0.0 0.46 9.7 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 GAP85025.1 - 0.16 11.7 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF1388 PF07142.12 GAP85026.1 - 0.0051 16.7 1.9 0.013 15.4 1.9 1.6 1 0 0 1 1 1 1 Repeat of unknown function (DUF1388) IBR PF01485.21 GAP85027.1 - 2.1e-21 75.9 43.8 3.6e-11 43.1 3.6 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 GAP85027.1 - 0.0003 20.6 4.4 0.0003 20.6 4.4 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP85027.1 - 0.0013 19.0 6.4 0.0013 19.0 6.4 3.9 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAP85027.1 - 0.0035 17.1 4.2 0.0035 17.1 4.2 4.8 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.8 GAP85027.1 - 0.013 16.0 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-RING_UBOX PF13445.6 GAP85027.1 - 0.022 14.8 4.0 0.022 14.8 4.0 3.8 3 1 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAP85027.1 - 0.39 10.9 28.9 0.21 11.8 3.2 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 GAP85027.1 - 4 7.3 39.8 4.2 7.2 3.9 4.2 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain XPG_I PF00867.18 GAP85028.1 - 9.1e-23 80.4 0.0 1.6e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GAP85028.1 - 1.1e-22 80.4 0.0 2.1e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 GAP85028.1 - 0.00015 21.3 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 GAP85028.1 - 0.0039 17.8 0.0 0.012 16.2 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Peptidase_M42 PF05343.14 GAP85028.1 - 0.075 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase CX9C PF16860.5 GAP85028.1 - 0.15 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, HHH_5 PF14520.6 GAP85028.1 - 0.17 12.5 0.2 14 6.4 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix domain Tma16 PF11176.8 GAP85029.1 - 2.1e-44 150.9 2.5 2.5e-44 150.7 2.5 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 CHASE7 PF17151.4 GAP85029.1 - 0.08 12.5 0.2 0.13 11.8 0.1 1.4 1 1 0 1 1 1 0 Periplasmic sensor domain MAM33 PF02330.16 GAP85030.1 - 8.5e-71 238.3 0.9 1e-70 238.0 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Glyco_hydro_11 PF00457.17 GAP85031.1 - 5.4e-76 254.2 15.0 6.6e-76 253.9 15.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Transferase PF02458.15 GAP85032.1 - 1.2e-18 67.0 0.0 9.4e-18 64.1 0.0 2.0 1 1 0 1 1 1 1 Transferase family Apolipoprotein PF01442.18 GAP85033.1 - 0.04 13.8 2.5 0.06 13.2 2.5 1.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4758 PF15950.5 GAP85033.1 - 0.047 14.0 1.1 0.061 13.7 1.1 1.1 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein NgoMIV_restric PF09015.10 GAP85033.1 - 0.17 11.0 1.5 0.22 10.6 1.2 1.3 1 1 0 1 1 1 0 NgoMIV restriction enzyme DUF883 PF05957.13 GAP85033.1 - 0.18 12.4 8.0 0.24 12.0 3.7 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Bot1p PF12298.8 GAP85033.1 - 0.79 9.9 4.1 2.8 8.1 4.1 1.9 1 1 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Acyl_transf_3 PF01757.22 GAP85035.1 - 1.2e-23 83.8 21.2 1.2e-23 83.8 21.2 1.4 1 1 0 1 1 1 1 Acyltransferase family p450 PF00067.22 GAP85036.1 - 3.9e-43 147.9 0.0 1.7e-39 135.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Gag_p30 PF02093.16 GAP85036.1 - 0.015 14.9 0.1 0.049 13.1 0.0 1.9 2 0 0 2 2 2 0 Gag P30 core shell protein DUF4570 PF15134.6 GAP85036.1 - 0.026 14.5 0.1 0.052 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Pkinase PF00069.25 GAP85037.1 - 9.2e-28 97.3 0.0 1.2e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP85037.1 - 1.2e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP85037.1 - 0.00096 18.0 0.3 0.0014 17.5 0.3 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAP85037.1 - 0.012 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Drc1-Sld2 PF11719.8 GAP85038.1 - 3.3e-97 326.9 26.2 3.8e-97 326.7 26.2 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein eIF-3c_N PF05470.12 GAP85038.1 - 2 6.6 7.1 3.2 6.0 7.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus zf-RING_2 PF13639.6 GAP85039.1 - 5.7e-07 29.8 12.2 9.6e-07 29.0 12.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAP85039.1 - 2e-06 27.5 8.3 3.3e-06 26.8 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP85039.1 - 1.2e-05 25.0 11.9 2.1e-05 24.2 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP85039.1 - 0.0013 18.6 13.1 0.002 17.9 13.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAP85039.1 - 0.0051 17.1 8.8 0.02 15.2 8.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 GAP85039.1 - 0.33 10.8 7.9 0.63 9.9 7.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1996 PF09362.10 GAP85040.1 - 2.9e-68 230.4 4.1 4.4e-68 229.8 4.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gal_mutarotas_2 PF13802.6 GAP85040.1 - 0.04 14.3 0.3 0.087 13.2 0.3 1.7 1 1 0 1 1 1 0 Galactose mutarotase-like Methyltransf_23 PF13489.6 GAP85041.1 - 2e-22 79.8 0.0 3.2e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP85041.1 - 1.8e-08 34.9 0.0 4.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP85041.1 - 6.3e-08 32.5 0.0 5.2e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP85041.1 - 6.6e-07 30.0 0.0 4.6e-06 27.3 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP85041.1 - 0.00012 22.6 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAP85041.1 - 0.0064 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 GAP85041.1 - 0.047 13.1 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 GAP85041.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase GidB PF02527.15 GAP85041.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Dabb PF07876.12 GAP85042.1 - 1.1e-24 86.9 0.0 1.2e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain IL1 PF00340.19 GAP85042.1 - 0.14 11.8 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Interleukin-1 / 18 Osmo_CC PF08946.10 GAP85045.1 - 0.022 15.0 0.4 0.058 13.7 0.4 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Helo_like_N PF17111.5 GAP85045.1 - 0.14 11.5 3.9 0.67 9.3 0.0 2.9 2 1 1 3 3 3 0 Fungal N-terminal domain of STAND proteins zf-GRF PF06839.12 GAP85046.1 - 7.3e-08 32.4 1.2 7.3e-08 32.4 1.2 2.3 2 0 0 2 2 2 1 GRF zinc finger Zn_clus PF00172.18 GAP85046.1 - 6.5e-05 23.0 11.3 6.5e-05 23.0 11.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 GAP85046.1 - 0.00015 21.8 9.2 0.00033 20.7 9.2 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAP85046.1 - 0.0077 16.3 6.2 0.017 15.2 6.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor TTKRSYEDQ PF10212.9 GAP85046.1 - 0.2 10.6 0.2 0.38 9.7 0.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein zf-met PF12874.7 GAP85046.1 - 0.43 11.0 6.8 7.3 7.1 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAP85046.1 - 0.69 10.9 12.0 2.9 9.0 0.0 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Choline_transpo PF04515.12 GAP85047.1 - 4.5e-78 262.7 24.2 4.5e-78 262.7 24.2 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF202 PF02656.15 GAP85047.1 - 0.033 14.6 1.2 0.033 14.6 1.2 5.4 3 1 1 4 4 4 0 Domain of unknown function (DUF202) Galanin PF01296.18 GAP85048.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Galanin F-box-like PF12937.7 GAP85049.1 - 0.0012 18.7 0.0 0.0034 17.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP85049.1 - 0.024 14.5 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box domain FSH1 PF03959.13 GAP85050.1 - 1.2e-24 87.1 0.0 1.6e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) AAA_12 PF13087.6 GAP85051.1 - 3.8e-39 134.4 0.0 6.8e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAP85051.1 - 7.9e-16 58.6 2.1 1.6e-15 57.6 2.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAP85051.1 - 0.074 13.4 0.0 0.81 10.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain zf-CCCH PF00642.24 GAP85051.1 - 0.18 11.8 0.6 0.4 10.6 0.6 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CFEM PF05730.11 GAP85052.1 - 1e-10 41.5 12.8 1.2e-10 41.3 12.8 1.1 1 0 0 1 1 1 1 CFEM domain LDcluster4 PF18306.1 GAP85052.1 - 0.034 13.7 0.5 0.04 13.5 0.5 1.2 1 0 0 1 1 1 0 SLOG cluster4 family Fungal_trans_2 PF11951.8 GAP85053.1 - 7.9e-06 24.9 0.0 1.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3Beta_HSD PF01073.19 GAP85054.1 - 1.2e-20 73.7 0.0 2.2e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAP85054.1 - 7.7e-11 41.9 0.1 3e-10 40.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAP85054.1 - 1.3e-09 37.7 0.1 4.8e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 GAP85054.1 - 5.1e-06 26.5 0.3 9.1e-06 25.7 0.3 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAP85054.1 - 0.00074 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAP85054.1 - 0.0081 15.7 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 GAP85054.1 - 0.11 11.7 0.7 1.8 7.6 0.7 2.2 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Thioesterase PF00975.20 GAP85057.1 - 4.6e-11 43.3 0.0 7.4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 GAP85057.1 - 0.00011 22.8 0.0 0.00022 21.9 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF3638 PF12340.8 GAP85058.1 - 6.3e-96 320.1 0.1 1.3e-95 319.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 GAP85058.1 - 2.2e-16 58.9 0.7 4.2e-16 58.0 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Adaptin_N PF01602.20 GAP85060.1 - 2.9e-137 458.4 2.5 4e-137 458.0 2.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAP85060.1 - 1.8e-63 213.4 2.9 1e-61 207.7 0.1 2.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAP85060.1 - 1.2e-17 64.1 0.3 4e-08 33.5 0.0 5.3 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.22 GAP85060.1 - 4.1e-10 39.0 8.6 0.012 15.8 0.0 6.7 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 GAP85060.1 - 2e-05 25.0 0.2 0.63 10.6 0.0 5.2 3 1 1 4 4 4 1 HEAT-like repeat UNC45-central PF11701.8 GAP85060.1 - 0.002 18.1 0.7 0.064 13.2 0.1 2.8 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 GAP85060.1 - 0.0096 16.1 0.4 0.82 9.9 0.0 3.8 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 GAP85060.1 - 0.027 14.0 0.2 2.1 7.8 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal NIF3 PF01784.18 GAP85061.1 - 3.2e-61 207.1 0.0 4e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Vps51 PF08700.11 GAP85062.1 - 5.5e-28 96.9 0.2 9.4e-28 96.1 0.2 1.4 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 GAP85062.1 - 0.00017 20.4 0.5 0.00021 20.1 0.5 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 GAP85062.1 - 0.00036 20.7 0.3 0.00058 20.0 0.3 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 COG2 PF06148.11 GAP85062.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 RMI1_N PF08585.12 GAP85063.1 - 6.6e-48 163.3 0.0 9.2e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 RecQ mediated genome instability protein HET PF06985.11 GAP85063.1 - 3.6e-13 50.1 3.4 3.6e-11 43.6 3.4 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CATSPERD PF15020.6 GAP85063.1 - 0.11 10.8 0.0 0.35 9.1 0.0 1.7 2 0 0 2 2 2 0 Cation channel sperm-associated protein subunit delta Abhydrolase_3 PF07859.13 GAP85065.1 - 2.8e-15 56.7 0.0 3.7e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 GAP85066.1 - 6.6e-26 91.1 33.4 1.1e-15 57.4 2.7 3.0 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP85066.1 - 1.1e-09 37.7 2.8 1.1e-09 37.7 2.8 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 GAP85066.1 - 4.1e-09 35.4 7.9 4.1e-09 35.4 7.9 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3522 PF12036.8 GAP85066.1 - 0.033 14.5 1.4 0.19 12.0 1.0 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) ADH_N PF08240.12 GAP85067.1 - 8.1e-28 96.5 1.4 1.4e-27 95.7 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP85067.1 - 1.1e-17 64.2 0.0 2.1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP85067.1 - 0.00054 21.0 0.0 0.0011 20.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAP85067.1 - 0.0029 17.1 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 GAP85067.1 - 0.061 13.3 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 GAP85067.1 - 0.092 12.0 1.0 0.17 11.2 1.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DDE_Tnp_IS66_C PF13817.6 GAP85067.1 - 0.099 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 IS66 C-terminal element p450 PF00067.22 GAP85068.1 - 8e-60 202.9 0.0 9.5e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_20 PF00982.21 GAP85069.1 - 1e-148 495.9 0.0 1.6e-148 495.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAP85069.1 - 1.6e-70 236.9 0.0 3.1e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 GAP85069.1 - 0.06 12.9 0.0 0.5 9.9 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferases group 1 COG5 PF10392.9 GAP85070.1 - 1.2e-38 132.3 3.5 1.4e-38 132.0 0.4 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Peptidase_M41 PF01434.18 GAP85070.1 - 0.047 13.5 1.0 0.11 12.3 0.4 1.8 2 0 0 2 2 2 0 Peptidase family M41 Seryl_tRNA_N PF02403.22 GAP85070.1 - 0.091 13.0 0.4 16 5.8 0.9 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SKA1 PF07160.12 GAP85070.1 - 0.22 11.3 2.3 0.4 10.5 1.9 1.5 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF3810 PF12725.7 GAP85072.1 - 0.0018 17.7 0.3 0.0041 16.5 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3810) Peptidase_M57 PF12388.8 GAP85072.1 - 0.057 13.0 0.7 5 6.7 0.0 2.2 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase DUF3144 PF11342.8 GAP85072.1 - 5.4 7.4 9.3 0.34 11.2 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3144) COesterase PF00135.28 GAP85073.1 - 1.2e-81 275.2 0.0 3.1e-81 273.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP85073.1 - 6.2e-06 26.2 0.1 2e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP85073.1 - 0.046 13.2 0.7 0.072 12.5 0.7 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Dabb PF07876.12 GAP85074.1 - 5.8e-05 23.6 0.3 7.5e-05 23.3 0.3 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Lectin_C PF00059.21 GAP85074.1 - 0.0037 18.0 0.4 0.0044 17.7 0.4 1.1 1 0 0 1 1 1 1 Lectin C-type domain ETC_C1_NDUFA4 PF04800.12 GAP85074.1 - 0.065 13.5 3.1 0.26 11.6 0.5 2.3 1 1 1 2 2 2 0 ETC complex I subunit conserved region ketoacyl-synt PF00109.26 GAP85075.1 - 7.2e-69 232.2 0.1 1.4e-68 231.3 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP85075.1 - 4.6e-54 183.0 0.4 1.1e-53 181.8 0.1 1.9 2 0 0 2 2 2 1 KR domain Condensation PF00668.20 GAP85075.1 - 3.2e-44 151.4 0.0 4.9e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 GAP85075.1 - 2.2e-41 142.0 0.1 4e-41 141.2 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP85075.1 - 9.5e-37 127.2 0.1 4.7e-36 124.9 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP85075.1 - 1.3e-28 99.3 0.0 3e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAP85075.1 - 5.2e-15 55.9 0.0 1.4e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAP85075.1 - 3.8e-09 36.3 0.0 9.1e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.12 GAP85075.1 - 3.3e-05 24.6 0.0 0.00024 21.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 GAP85075.1 - 0.00012 22.4 0.1 0.00038 20.7 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 GAP85075.1 - 0.00029 20.7 0.0 0.00071 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP85075.1 - 0.0016 18.2 0.0 0.0046 16.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP85075.1 - 0.0029 17.0 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 GAP85075.1 - 0.0049 16.3 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 GAP85075.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 GAP85075.1 - 0.008 16.0 1.3 0.14 12.1 1.3 2.5 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_11 PF08241.12 GAP85075.1 - 0.0094 16.6 0.0 0.026 15.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 GAP85075.1 - 0.094 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PKD_channel PF08016.12 GAP85076.1 - 0.55 8.9 9.4 2.3 6.8 0.7 2.1 2 0 0 2 2 2 0 Polycystin cation channel p450 PF00067.22 GAP85077.1 - 1e-53 182.7 0.0 1.3e-53 182.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAP85078.1 - 3.6e-33 115.0 51.4 3.6e-33 115.0 51.4 2.9 2 2 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP85078.1 - 3.3e-11 42.7 18.1 3.3e-11 42.7 18.1 2.8 2 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 GAP85078.1 - 4.1e-10 38.7 14.8 6e-10 38.2 14.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF43 PF01861.16 GAP85078.1 - 0.19 10.9 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain 4HBT_3 PF13622.6 GAP85079.1 - 6.7e-36 124.8 0.5 7.6e-36 124.6 0.5 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily APH PF01636.23 GAP85081.1 - 0.0061 16.5 0.4 0.11 12.4 0.0 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Prenylcys_lyase PF07156.14 GAP85082.1 - 8.2e-91 304.8 0.0 1e-90 304.5 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 GAP85082.1 - 4.4e-14 52.5 0.1 1.3e-13 51.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAP85082.1 - 1.6e-12 47.5 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 GAP85082.1 - 1.2e-07 31.7 1.3 2.1e-05 24.3 1.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP85082.1 - 0.00022 20.6 0.3 0.011 15.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP85082.1 - 0.001 19.1 0.4 0.0026 17.8 0.1 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAP85082.1 - 0.021 15.4 0.7 0.48 11.0 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP85082.1 - 0.023 13.4 1.3 0.18 10.5 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 GAP85082.1 - 0.034 13.4 0.1 0.074 12.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 GAP85082.1 - 0.063 12.1 0.3 0.1 11.4 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.16 GAP85082.1 - 0.15 11.7 1.0 0.4 10.3 0.4 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF3433 PF11915.8 GAP85083.1 - 1.4e-28 99.2 23.2 3.1e-18 66.0 7.3 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) COX2_TM PF02790.15 GAP85083.1 - 4.4e-05 23.5 6.5 0.038 14.1 1.3 3.0 2 0 0 2 2 2 2 Cytochrome C oxidase subunit II, transmembrane domain SK_channel PF03530.14 GAP85083.1 - 4.2 7.4 5.5 5.1 7.1 1.9 2.9 2 1 0 2 2 2 0 Calcium-activated SK potassium channel HD_assoc PF13286.6 GAP85084.1 - 0.082 13.5 0.4 0.35 11.4 0.4 2.1 1 1 0 1 1 1 0 Phosphohydrolase-associated domain 2-Hacid_dh_C PF02826.19 GAP85085.1 - 4.8e-39 133.6 0.0 6.9e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP85085.1 - 1.3e-11 44.2 0.0 1.8e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 GAP85085.1 - 0.0078 16.8 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 GAP85085.1 - 0.01 16.1 0.0 0.34 11.2 0.0 2.4 1 1 0 1 1 1 0 TrkA-N domain Gp_dh_N PF00044.24 GAP85085.1 - 0.035 14.4 0.0 0.065 13.6 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain UDPG_MGDP_dh_C PF03720.15 GAP85085.1 - 0.038 14.4 0.1 10 6.6 0.0 3.0 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DapB_N PF01113.20 GAP85085.1 - 0.041 14.0 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_7 PF13241.6 GAP85085.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Mito_carr PF00153.27 GAP85086.1 - 1.9e-53 178.3 3.7 8.5e-20 70.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.13 GAP85087.1 - 1.6e-175 584.8 0.0 2.3e-175 584.3 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.10 GAP85087.1 - 7.2e-06 26.6 1.4 0.0042 17.6 1.9 2.9 2 0 0 2 2 2 1 CRISPR-associated protein Cse2 (CRISPR_cse2) DHR10 PF18595.1 GAP85087.1 - 0.048 13.7 0.4 0.048 13.7 0.4 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Orthopox_A5L PF06193.11 GAP85087.1 - 0.098 12.1 1.2 0.2 11.1 1.2 1.5 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Sec8_exocyst PF04048.14 GAP85087.1 - 0.13 12.1 0.6 7 6.5 0.2 3.0 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 GAP85087.1 - 0.16 12.0 0.5 0.72 9.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 GAP85087.1 - 0.54 10.3 2.5 2.5 8.2 1.1 2.8 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4164 PF13747.6 GAP85087.1 - 0.56 10.5 10.0 0.15 12.3 3.4 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) ABC_tran PF00005.27 GAP85088.1 - 2.2e-33 115.7 0.0 3.1e-17 63.4 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAP85088.1 - 3.2e-12 46.3 2.3 0.00028 20.4 0.0 3.9 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 GAP85088.1 - 3.5e-12 45.9 4.8 3.5e-12 45.9 4.8 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 GAP85088.1 - 1.2e-09 38.5 7.4 0.028 14.2 0.0 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 GAP85088.1 - 3.2e-06 27.5 0.0 0.0012 19.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAP85088.1 - 1.2e-05 25.8 0.1 0.036 14.5 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP85088.1 - 3e-05 24.5 0.0 0.094 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Fer4 PF00037.27 GAP85088.1 - 4.5e-05 23.1 2.8 4.5e-05 23.1 2.8 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 GAP85088.1 - 6.6e-05 22.8 0.8 0.53 9.9 0.0 3.1 5 0 0 5 5 3 2 AAA ATPase domain SRP54 PF00448.22 GAP85088.1 - 0.00019 21.2 2.7 0.026 14.2 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 GAP85088.1 - 0.0002 21.3 0.0 0.76 9.7 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase RNA_helicase PF00910.22 GAP85088.1 - 0.00024 21.4 0.1 0.26 11.7 0.1 2.8 3 0 0 3 3 2 1 RNA helicase AAA_23 PF13476.6 GAP85088.1 - 0.00035 21.1 0.5 0.044 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAP85088.1 - 0.00047 19.9 0.5 0.073 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAP85088.1 - 0.00053 19.9 0.1 0.52 10.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 GAP85088.1 - 0.00059 19.5 0.3 0.69 9.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_13 PF13166.6 GAP85088.1 - 0.00063 18.5 0.6 0.0025 16.6 0.0 2.2 3 0 0 3 3 3 1 AAA domain Fer4_10 PF13237.6 GAP85088.1 - 0.001 19.1 8.4 0.016 15.3 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Rad17 PF03215.15 GAP85088.1 - 0.0012 18.8 0.1 0.45 10.4 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_21 PF14697.6 GAP85088.1 - 0.0017 18.4 10.5 0.0043 17.2 10.5 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAP85088.1 - 0.0018 18.3 1.2 0.0018 18.3 1.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 GAP85088.1 - 0.0022 18.2 0.1 2.8 8.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAP85088.1 - 0.0036 17.9 0.1 6 7.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 GAP85088.1 - 0.0038 17.0 0.1 3.3 7.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 GAP85088.1 - 0.0048 16.9 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 GAP85088.1 - 0.0048 16.6 0.1 1.6 8.3 0.0 2.6 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 GAP85088.1 - 0.0068 16.7 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAP85088.1 - 0.022 14.3 1.3 0.25 10.8 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 GAP85088.1 - 0.03 13.5 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Fer4_7 PF12838.7 GAP85088.1 - 0.043 14.4 0.7 0.043 14.4 0.7 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAP85088.1 - 0.067 13.4 11.0 0.14 12.3 11.0 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain MMR_HSR1 PF01926.23 GAP85088.1 - 0.093 12.8 0.4 22 5.2 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Fer4_16 PF13484.6 GAP85088.1 - 0.093 13.7 0.2 0.093 13.7 0.2 2.7 2 0 0 2 2 1 0 4Fe-4S double cluster binding domain TniB PF05621.11 GAP85088.1 - 0.11 11.9 0.0 2.1 7.7 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein Mg_chelatase PF01078.21 GAP85088.1 - 0.12 11.8 0.7 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GAP85088.1 - 0.13 12.3 0.7 27 4.8 0.1 3.3 2 1 1 3 3 3 0 AAA domain MukB PF04310.12 GAP85088.1 - 0.15 11.9 0.1 8.2 6.2 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal DnaB_C PF03796.15 GAP85088.1 - 0.15 11.4 0.0 0.34 10.2 0.0 1.6 2 0 0 2 2 1 0 DnaB-like helicase C terminal domain Rad51 PF08423.11 GAP85088.1 - 0.17 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Rad51 NTPase_1 PF03266.15 GAP85088.1 - 0.23 11.4 3.8 4 7.3 0.2 3.0 3 0 0 3 3 3 0 NTPase AAA_5 PF07728.14 GAP85088.1 - 0.26 11.3 3.1 4.8 7.2 0.0 3.2 3 1 1 4 4 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 GAP85088.1 - 0.36 10.6 3.1 1 9.1 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_2 PF12797.7 GAP85088.1 - 4.4 7.6 10.2 0.68 10.2 1.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain p450 PF00067.22 GAP85089.1 - 9.6e-65 219.1 0.0 1.2e-64 218.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAP85090.1 - 1.5e-36 126.2 0.1 2.5e-20 72.7 0.0 2.7 1 1 1 2 2 2 2 Cytochrome P450 Terpene_synth_C PF03936.16 GAP85091.1 - 0.00086 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF4812 PF16071.5 GAP85091.1 - 0.0029 17.4 0.2 0.007 16.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4812) TRI5 PF06330.11 GAP85091.1 - 0.0099 14.8 0.1 0.024 13.5 0.0 1.6 2 0 0 2 2 2 1 Trichodiene synthase (TRI5) Sulfotransfer_4 PF17784.1 GAP85092.1 - 4.6e-66 222.7 0.0 5.5e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAP85092.1 - 0.011 16.1 0.1 1.9 8.8 0.0 2.2 1 1 1 2 2 2 0 Sulfotransferase family HET PF06985.11 GAP85093.1 - 2.1e-12 47.6 8.1 1.4e-09 38.4 2.6 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HNH_2 PF13391.6 GAP85094.1 - 6.5e-14 51.8 0.0 1.6e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease ParE_toxin PF05016.15 GAP85094.1 - 0.11 13.1 0.0 3.8 8.2 0.0 2.7 3 0 0 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE CN_hydrolase PF00795.22 GAP85095.1 - 3.1e-47 161.1 0.0 3.7e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_S48 PF03574.15 GAP85095.1 - 0.097 12.9 0.0 0.3 11.3 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S48 p450 PF00067.22 GAP85097.1 - 2.3e-29 102.5 0.0 4.3e-29 101.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAP85098.1 - 4.5e-09 35.6 0.0 3.4e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 ABC2_membrane PF01061.24 GAP85100.1 - 6.4e-72 241.4 41.8 1.1e-39 136.1 17.2 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 GAP85100.1 - 4.7e-33 114.6 0.0 3.6e-15 56.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAP85100.1 - 7.2e-24 83.5 0.0 7.2e-24 83.5 0.0 2.4 3 0 0 3 3 2 1 CDR ABC transporter AAA_16 PF13191.6 GAP85100.1 - 0.00049 20.5 0.7 0.0066 16.9 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAP85100.1 - 0.00076 19.4 0.2 0.0048 16.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 GAP85100.1 - 0.0017 17.8 0.0 1 8.8 0.0 3.4 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 GAP85100.1 - 0.0021 17.2 40.4 0.13 11.3 20.4 3.2 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.6 GAP85100.1 - 0.0033 17.0 1.9 0.03 13.9 0.3 2.8 3 0 0 3 3 3 1 AAA domain ABC_trans_N PF14510.6 GAP85100.1 - 0.0063 17.1 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal MMR_HSR1 PF01926.23 GAP85100.1 - 0.012 15.7 0.2 0.3 11.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 GAP85100.1 - 0.04 13.7 0.0 6.8 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 GAP85100.1 - 0.088 13.4 0.1 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 GAP85100.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase NACHT PF05729.12 GAP85100.1 - 0.21 11.5 3.7 11 5.9 0.2 3.6 3 0 0 3 3 3 0 NACHT domain AAA_29 PF13555.6 GAP85100.1 - 0.29 10.9 1.8 17 5.2 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 GAP85100.1 - 0.48 10.6 1.4 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 GAP85100.1 - 1.2 8.7 3.9 0.27 10.8 0.4 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain p450 PF00067.22 GAP85101.1 - 1.1e-31 110.2 0.0 5.4e-31 107.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 AAA PF00004.29 GAP85103.1 - 3.4e-17 63.1 0.0 7e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP85103.1 - 0.00011 22.6 0.1 0.00063 20.2 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP85103.1 - 0.00017 21.9 0.2 0.0012 19.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAP85103.1 - 0.00048 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAP85103.1 - 0.0037 17.8 0.0 0.019 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 GAP85103.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAP85103.1 - 0.024 14.8 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAP85103.1 - 0.062 13.6 0.2 0.32 11.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 GAP85103.1 - 0.14 11.7 0.0 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 GAP85103.1 - 0.25 11.6 1.4 1.1 9.5 0.0 2.5 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain AIM24 PF01987.17 GAP85105.1 - 9.7e-50 169.2 0.2 1.2e-49 168.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 MFS_1 PF07690.16 GAP85106.1 - 1.1e-34 119.9 70.3 7.9e-31 107.3 44.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAP85106.1 - 0.07 12.0 20.7 0.069 12.0 4.1 3.6 2 2 1 3 3 3 0 MFS_1 like family Hva1_TUDOR PF11160.8 GAP85108.1 - 3.8e-16 59.0 1.9 3.8e-16 59.0 1.9 2.7 3 0 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain TMEM119 PF15724.5 GAP85108.1 - 0.013 15.6 5.8 0.013 15.6 5.8 2.2 1 1 1 2 2 2 0 TMEM119 family ECH_1 PF00378.20 GAP85109.1 - 3.3e-36 124.9 0.0 4.7e-30 104.7 0.0 3.0 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAP85109.1 - 2.3e-23 83.3 0.1 8e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Ank_2 PF12796.7 GAP85110.1 - 6e-12 46.0 0.0 9.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP85110.1 - 3.1e-11 43.3 0.4 1.9e-08 34.4 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAP85110.1 - 9.7e-10 38.8 0.5 2.1e-05 25.0 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP85110.1 - 5.5e-09 35.5 0.0 2.4e-05 24.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 GAP85110.1 - 3.3e-08 33.6 0.1 4.4e-06 26.9 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat Peptidase_M6 PF05547.11 GAP85111.1 - 2.1e-07 29.7 0.2 0.0084 14.5 0.0 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 7TMR-DISMED2 PF07696.11 GAP85111.1 - 0.012 15.7 0.0 0.62 10.1 0.0 2.4 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 Peptidase_S28 PF05577.12 GAP85112.1 - 1.2e-43 149.5 0.5 1.5e-34 119.6 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Sec7 PF01369.20 GAP85114.1 - 9.9e-29 100.3 0.6 1.9e-28 99.4 0.1 1.6 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 GAP85114.1 - 7.3e-20 71.5 0.0 1.5e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain AA_permease_2 PF13520.6 GAP85115.1 - 1.3e-49 169.2 43.0 1.8e-49 168.8 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP85115.1 - 9.9e-22 77.2 34.3 1.4e-21 76.7 34.3 1.2 1 0 0 1 1 1 1 Amino acid permease Phage_holin_3_5 PF16085.5 GAP85115.1 - 0.067 13.3 3.7 0.23 11.6 3.7 2.0 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III CLLAC PF15675.5 GAP85115.1 - 0.33 10.5 5.5 1.2 8.7 5.5 2.1 1 0 0 1 1 1 0 CLLAC-motif containing domain ketoacyl-synt PF00109.26 GAP85116.1 - 5.7e-67 225.9 0.1 1.1e-66 225.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAP85116.1 - 3.1e-45 154.8 0.0 6.9e-45 153.7 0.0 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ketoacyl-synt_C PF02801.22 GAP85116.1 - 1.4e-34 118.6 0.1 3.4e-34 117.4 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 GAP85116.1 - 1.1e-29 103.9 0.0 3.6e-29 102.3 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Thioesterase PF00975.20 GAP85116.1 - 7.3e-17 62.3 0.0 4.5e-16 59.7 0.0 2.3 1 1 0 1 1 1 1 Thioesterase domain PS-DH PF14765.6 GAP85116.1 - 1.7e-13 50.5 0.0 3.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 GAP85116.1 - 1.8e-08 34.6 0.1 5e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAP85116.1 - 6.1e-06 26.7 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 GAP85116.1 - 0.022 14.2 0.1 0.06 12.7 0.1 1.7 1 0 0 1 1 1 0 Thiolase, N-terminal domain Hydrolase_4 PF12146.8 GAP85116.1 - 0.11 11.8 0.0 0.61 9.3 0.0 2.2 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAP85116.1 - 2.9 8.4 10.4 0.17 12.4 0.2 3.4 3 2 0 3 3 3 0 Alpha/beta hydrolase family Amidohydro_3 PF07969.11 GAP85117.1 - 1e-15 58.2 2.0 8.4e-10 38.7 0.0 3.3 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_1 PF01979.20 GAP85117.1 - 2.2e-09 37.1 0.6 7.8e-08 32.0 0.0 3.0 4 0 0 4 4 4 1 Amidohydrolase family DUF4131 PF13567.6 GAP85117.1 - 0.043 13.5 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) p450 PF00067.22 GAP85118.1 - 5.4e-37 127.6 0.0 7.6e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_4 PF01063.19 GAP85119.1 - 1.1e-06 28.7 0.0 1.3e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV NUDIX PF00293.28 GAP85120.1 - 8.7e-07 29.1 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 GAP85120.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) MFS_1 PF07690.16 GAP85121.1 - 6.1e-23 81.3 61.8 6.1e-21 74.7 34.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.6 GAP85122.1 - 6e-07 30.0 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Menin PF05053.13 GAP85122.1 - 0.13 10.6 1.7 0.21 9.9 1.7 1.2 1 0 0 1 1 1 0 Menin CPSF100_C PF13299.6 GAP85122.1 - 0.69 10.1 3.3 2 8.6 1.0 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Mucin PF01456.17 GAP85122.1 - 0.93 9.5 9.2 1.6 8.7 9.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PTPRCAP PF15713.5 GAP85122.1 - 5.8 7.2 12.1 3.2 8.0 6.8 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF809 PF05663.11 GAP85122.1 - 7.7 6.7 5.9 4.3 7.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF809) PIP5K PF01504.18 GAP85123.1 - 9.2e-44 149.7 0.0 1.5e-43 149.0 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MOSC PF03473.17 GAP85124.1 - 1.9e-21 76.5 0.0 3.4e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 MOSC domain 3-alpha PF03475.14 GAP85124.1 - 2.4e-12 46.5 0.0 5e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 3-alpha domain Fer2 PF00111.27 GAP85124.1 - 2.4e-09 37.0 1.1 4.4e-09 36.2 1.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 GAP85124.1 - 0.0023 18.5 0.1 0.033 14.8 0.1 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAP85124.1 - 0.026 14.6 0.1 5 7.2 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain AAA PF00004.29 GAP85125.1 - 5.3e-16 59.2 0.0 9.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAP85125.1 - 0.00048 20.1 0.0 0.008 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP85125.1 - 0.001 19.4 0.3 0.0061 16.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 GAP85125.1 - 0.0032 17.8 0.4 0.011 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Torsin PF06309.11 GAP85125.1 - 0.0073 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_30 PF13604.6 GAP85125.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAP85125.1 - 0.05 13.9 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAP85125.1 - 0.083 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.14 GAP85125.1 - 0.09 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ORC6 PF05460.13 GAP85126.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Fimbrial_PilY2 PF14481.6 GAP85126.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Gpi1 PF05024.15 GAP85127.1 - 2.2e-76 256.1 8.8 4.3e-76 255.2 8.8 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.21 GAP85127.1 - 0.0048 16.3 0.8 0.013 14.8 0.8 1.7 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DNA_pol_A_exo1 PF01612.20 GAP85128.1 - 6.8e-40 136.6 0.1 1e-39 136.1 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 GAP85128.1 - 1.7e-28 99.2 0.7 4.3e-28 97.8 0.7 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 GAP85128.1 - 6.4e-14 51.7 0.0 1.3e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Nop53 PF07767.11 GAP85128.1 - 0.08 12.3 19.5 0.13 11.6 19.5 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Herpes_UL56 PF04534.12 GAP85128.1 - 0.49 9.9 4.7 1.1 8.7 4.7 1.5 1 0 0 1 1 1 0 Herpesvirus UL56 protein SEEEED PF14797.6 GAP85128.1 - 1.2 9.3 21.0 2.6 8.2 21.0 1.5 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Draxin PF15550.6 GAP85128.1 - 1.7 8.5 11.6 3.2 7.5 11.6 1.4 1 0 0 1 1 1 0 Draxin DUF3292 PF11696.8 GAP85128.1 - 9.1 4.5 9.7 14 3.9 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) UPF0203 PF05254.12 GAP85129.1 - 6.3e-26 90.4 3.2 7.4e-26 90.2 3.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 GAP85129.1 - 0.0033 17.8 2.0 0.0085 16.4 2.0 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 GAP85129.1 - 0.028 14.4 0.2 0.028 14.4 0.2 2.5 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2732 PF10809.8 GAP85129.1 - 0.036 13.9 0.1 0.048 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) UCR_hinge PF02320.16 GAP85129.1 - 0.3 11.3 4.0 0.85 9.9 4.0 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein PTR2 PF00854.21 GAP85130.1 - 9.9e-50 169.5 6.7 1.6e-49 168.8 5.3 1.8 1 1 1 2 2 2 1 POT family CcmH PF03918.14 GAP85130.1 - 0.068 12.5 0.7 5.8 6.2 0.0 2.7 2 1 1 3 3 3 0 Cytochrome C biogenesis protein Oxidored_q2 PF00420.24 GAP85130.1 - 5.1 6.8 7.8 1.2 8.8 1.5 2.8 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Peptidase_M28 PF04389.17 GAP85132.1 - 3.1e-38 131.5 0.0 4.7e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAP85132.1 - 5.4e-12 45.6 1.7 1.1e-11 44.6 1.7 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 GAP85132.1 - 0.0013 18.5 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Y_phosphatase PF00102.27 GAP85133.1 - 3.2e-49 167.6 0.0 4.6e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAP85133.1 - 0.00014 22.0 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 GAP85133.1 - 0.00041 20.4 0.0 0.00074 19.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 GAP85133.1 - 0.053 13.3 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Folliculin PF11704.8 GAP85135.1 - 1.1e-59 201.4 0.0 3.3e-59 199.9 0.0 1.8 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport K_channel_TID PF07941.11 GAP85135.1 - 0.53 10.8 6.9 0.78 10.2 4.7 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain MFS_1 PF07690.16 GAP85136.1 - 2.1e-32 112.4 27.7 2.1e-32 112.4 27.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DLH PF01738.18 GAP85138.1 - 3.1e-05 23.6 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family NIF3 PF01784.18 GAP85138.1 - 0.025 14.2 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) DLH PF01738.18 GAP85139.1 - 3.2e-11 43.2 0.1 3.5e-11 43.1 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Fungal_trans PF04082.18 GAP85140.1 - 2.2e-10 40.0 0.1 3.7e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85140.1 - 8.9e-09 35.3 7.7 1.7e-08 34.4 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAP85141.1 - 1.1e-24 87.0 30.2 1.6e-24 86.5 30.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fig1 PF12351.8 GAP85142.1 - 2.4e-59 200.4 2.8 2.4e-59 200.4 2.8 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 GAP85142.1 - 8e-09 35.4 9.4 1.3e-08 34.7 9.4 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 GAP85142.1 - 0.0018 17.4 9.0 0.0032 16.6 9.0 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF751 PF05421.11 GAP85142.1 - 0.3 11.8 0.1 0.3 11.8 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF751) DUF2976 PF11190.8 GAP85142.1 - 4.1 7.3 0.0 4.1 7.3 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) DUF2207 PF09972.9 GAP85142.1 - 9.4 4.9 16.6 0.34 9.6 0.3 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.16 GAP85143.1 - 3.1e-41 141.5 47.0 2e-40 138.8 45.4 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP85143.1 - 4.3e-17 61.8 25.3 4.5e-17 61.7 24.6 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP85143.1 - 7e-10 38.3 12.4 7e-10 38.3 12.4 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.22 GAP85144.1 - 2e-26 92.7 0.0 2.8e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 gpUL132 PF11359.8 GAP85144.1 - 0.26 10.8 0.9 0.54 9.8 0.9 1.5 1 0 0 1 1 1 0 Glycoprotein UL132 PsbH PF00737.20 GAP85145.1 - 0.065 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Baculo_11_kDa PF06143.11 GAP85145.1 - 1.1 8.9 6.3 2 8.0 6.3 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Glyco_hydro_47 PF01532.20 GAP85146.1 - 1e-180 601.5 0.1 1.3e-180 601.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 GAP85146.1 - 0.37 10.3 2.7 0.53 9.7 0.7 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 AA_permease PF00324.21 GAP85148.1 - 4.2e-126 421.3 44.4 4.8e-126 421.2 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP85148.1 - 1.7e-27 96.4 50.0 2.3e-27 95.9 50.0 1.1 1 0 0 1 1 1 1 Amino acid permease GMC_oxred_C PF05199.13 GAP85149.1 - 3e-25 89.4 0.0 6.6e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 GAP85149.1 - 9.3e-18 64.6 0.0 8e-14 51.7 0.0 3.1 3 0 0 3 3 3 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAP85149.1 - 0.00092 18.5 0.0 0.0059 15.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP85149.1 - 0.0015 17.7 0.0 0.077 12.1 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 GAP85149.1 - 0.0026 16.9 0.0 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAP85149.1 - 0.0095 15.2 0.0 3.4 6.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP85149.1 - 0.019 15.2 0.1 0.074 13.3 0.1 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAP85149.1 - 0.24 10.1 0.0 0.4 9.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein ADH_zinc_N PF00107.26 GAP85150.1 - 6.1e-30 103.9 2.8 1.3e-29 102.8 2.8 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP85150.1 - 9.6e-19 68.8 0.6 1.9e-18 67.8 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP85150.1 - 2e-11 43.7 0.0 7e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 GAP85150.1 - 6.1e-05 22.6 1.1 9.9e-05 21.9 1.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 GAP85150.1 - 0.002 18.4 0.1 0.0067 16.7 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain AlaDh_PNT_C PF01262.21 GAP85150.1 - 0.042 13.1 2.9 0.12 11.6 2.9 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AstE_AspA PF04952.14 GAP85150.1 - 0.05 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family WSC PF01822.19 GAP85152.1 - 1e-09 38.4 7.4 1e-09 38.4 7.4 1.8 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 GAP85152.1 - 1.3e-08 34.1 1.7 2.4e-08 33.2 1.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 GAP85152.1 - 0.00065 20.2 1.0 0.001 19.5 1.0 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4366 PF14283.6 GAP85152.1 - 0.0015 18.6 0.4 0.0026 17.8 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Podoplanin PF05808.11 GAP85152.1 - 0.0023 18.1 0.8 0.0036 17.4 0.8 1.3 1 0 0 1 1 1 1 Podoplanin DUF5305 PF17231.2 GAP85152.1 - 0.011 15.1 0.4 0.016 14.6 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Peptidase_M56 PF05569.11 GAP85152.1 - 0.011 14.9 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Insulin_TMD PF17870.1 GAP85152.1 - 0.012 15.6 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment BatD PF13584.6 GAP85152.1 - 0.015 14.2 0.2 0.02 13.7 0.2 1.1 1 0 0 1 1 1 0 Oxygen tolerance Amnionless PF14828.6 GAP85152.1 - 0.037 12.9 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF4448 PF14610.6 GAP85152.1 - 0.042 13.6 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Glycophorin_A PF01102.18 GAP85152.1 - 0.076 13.3 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Glycophorin A Alpha_GJ PF03229.13 GAP85152.1 - 0.08 13.5 2.3 0.16 12.5 2.3 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF2407_C PF13373.6 GAP85152.1 - 0.088 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain FTCD PF02971.14 GAP85152.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Formiminotransferase domain CbtA PF09490.10 GAP85152.1 - 0.13 12.0 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Gram_pos_anchor PF00746.21 GAP85152.1 - 0.18 11.7 0.5 0.55 10.2 0.5 1.9 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Adeno_E3_CR2 PF02439.15 GAP85152.1 - 0.25 11.1 1.4 0.47 10.3 1.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AtuA PF07287.11 GAP85154.1 - 3.1e-103 345.2 0.1 4.7e-103 344.6 0.1 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA FAD_binding_4 PF01565.23 GAP85155.1 - 8.9e-21 74.1 3.5 1.8e-20 73.1 3.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP85155.1 - 1.2e-11 44.5 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like APH PF01636.23 GAP85156.1 - 9.9e-38 130.4 0.0 1.7e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAP85156.1 - 2.1e-05 24.0 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 GAP85156.1 - 0.0011 17.9 0.0 0.02 13.8 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 GAP85156.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 GAP85156.1 - 0.022 14.3 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Acyl-CoA_dh_N PF02771.16 GAP85157.1 - 2.4e-07 31.4 0.1 9.5e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 GAP85158.1 - 8.7e-20 71.5 1.4 3.2e-19 69.6 1.4 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 GAP85158.1 - 7.9e-06 26.2 1.1 1.4e-05 25.4 1.1 1.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FHA PF00498.26 GAP85159.1 - 1.1e-13 51.3 0.0 2.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain AAA_16 PF13191.6 GAP85160.1 - 8.3e-08 32.8 0.1 4.3e-07 30.5 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 GAP85160.1 - 2.7e-05 23.5 0.0 4.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.14 GAP85160.1 - 0.019 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAP85160.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Pinin_SDK_N PF04697.13 GAP85161.1 - 0.094 13.4 5.2 0.17 12.5 5.2 1.5 1 1 0 1 1 1 0 pinin/SDK conserved region SpoIIE PF07228.12 GAP85162.1 - 0.068 13.1 0.0 0.083 12.8 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Glyco_hydro_88 PF07470.13 GAP85164.1 - 5.7e-10 38.8 0.1 8e-10 38.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 UcrQ PF02939.16 GAP85164.1 - 0.089 12.7 0.0 5.1 7.1 0.0 2.4 2 0 0 2 2 2 0 UcrQ family HET PF06985.11 GAP85165.1 - 3.5e-11 43.7 0.9 9.4e-11 42.3 0.9 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FTA2 PF13095.6 GAP85166.1 - 2.6e-40 138.4 0.3 5e-19 68.8 0.3 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 UCH PF00443.29 GAP85168.1 - 4.9e-38 131.1 0.7 2.2e-37 129.0 0.7 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAP85168.1 - 1.5e-07 31.3 2.1 1e-06 28.6 2.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4050 PF13259.6 GAP85168.1 - 0.016 15.6 0.8 0.016 15.6 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) PUB PF09409.10 GAP85168.1 - 0.016 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 PUB domain HLH PF00010.26 GAP85168.1 - 0.043 13.8 0.1 28 4.8 0.0 3.7 4 0 0 4 4 4 0 Helix-loop-helix DNA-binding domain zf-LYAR PF08790.11 GAP85168.1 - 3.5 7.6 4.8 1.7 8.7 1.7 2.0 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Tim17 PF02466.19 GAP85169.1 - 3e-06 27.6 9.7 4e-06 27.2 9.2 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Fst_toxin PF13955.6 GAP85170.1 - 0.16 11.9 0.4 0.35 10.8 0.4 1.6 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system HAD_SAK_1 PF10307.9 GAP85171.1 - 1.7e-76 256.6 0.0 2.6e-76 256.0 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins DNA_primase_S PF01896.19 GAP85172.1 - 3.2e-64 216.2 0.0 4.8e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 DNA primase small subunit XPC-binding PF09280.11 GAP85173.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 XPC-binding domain GATase1_like PF07090.11 GAP85174.1 - 0.091 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative glutamine amidotransferase MFS_1 PF07690.16 GAP85175.1 - 2.3e-33 115.6 52.4 2.1e-32 112.4 52.0 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP85175.1 - 5e-12 45.0 21.0 7.5e-12 44.5 20.0 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP85175.1 - 3.7e-08 32.7 28.9 6.2e-08 31.9 13.4 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter EthD PF07110.11 GAP85176.1 - 0.00032 21.8 0.4 0.00045 21.3 0.4 1.2 1 0 0 1 1 1 1 EthD domain JmjN PF02375.17 GAP85176.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 jmjN domain DUF1772 PF08592.11 GAP85177.1 - 0.0013 19.1 0.1 0.0019 18.5 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) ADH_N PF08240.12 GAP85178.1 - 0.0081 16.0 0.0 0.1 12.5 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.18 GAP85179.1 - 0.0015 18.6 6.3 0.0028 17.7 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Elf1 PF05129.13 GAP85179.1 - 0.08 13.0 0.9 0.22 11.6 0.9 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like LppX_LprAFG PF07161.13 GAP85179.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 LppX_LprAFG lipoprotein CFEM PF05730.11 GAP85180.1 - 1.5e-13 50.6 9.0 2.5e-13 49.9 9.0 1.3 1 0 0 1 1 1 1 CFEM domain DUF1100 PF06500.11 GAP85181.1 - 7.7e-11 41.4 0.0 1.7e-10 40.3 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 GAP85181.1 - 1.3e-09 38.9 0.8 3.5e-08 34.3 0.2 2.5 2 1 1 3 3 3 1 Alpha/beta hydrolase family Connexin40_C PF16791.5 GAP85181.1 - 0.0038 18.5 0.2 0.0068 17.6 0.2 1.4 1 0 0 1 1 1 1 Connexin 40 C-terminal domain Hydrolase_4 PF12146.8 GAP85181.1 - 0.019 14.2 0.0 0.087 12.1 0.0 2.0 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAP85181.1 - 0.035 13.6 0.0 0.082 12.4 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family ketoacyl-synt PF00109.26 GAP85182.1 - 4.5e-70 236.1 0.0 8e-70 235.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 GAP85182.1 - 9.3e-65 218.9 0.0 9.3e-64 215.6 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 GAP85182.1 - 1.5e-63 215.0 0.0 2.2e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 GAP85182.1 - 2.5e-54 183.9 0.1 1.5e-52 178.1 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 GAP85182.1 - 2.9e-46 158.1 0.0 5.6e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP85182.1 - 8.5e-45 153.6 0.0 1.6e-44 152.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP85182.1 - 1.2e-33 115.6 0.1 2.3e-33 114.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 GAP85182.1 - 2.4e-28 99.0 0.0 1.2e-27 96.7 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein KAsynt_C_assoc PF16197.5 GAP85182.1 - 6.8e-15 55.5 0.0 1.5e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 GAP85182.1 - 6.8e-13 48.8 1.0 3.9e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 GAP85182.1 - 6.9e-13 48.5 0.3 4.6e-12 45.8 0.1 2.5 3 0 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.21 GAP85182.1 - 7.8e-10 38.6 0.0 3.8e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAP85182.1 - 9e-07 28.2 0.0 0.028 13.4 0.0 3.3 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 GAP85182.1 - 6.6e-06 25.8 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AMP-binding_C PF13193.6 GAP85182.1 - 0.0027 18.7 0.0 0.0097 16.9 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 GAP85182.1 - 0.01 15.7 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding Thiolase_N PF00108.23 GAP85182.1 - 0.012 15.0 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain NmrA PF05368.13 GAP85182.1 - 0.028 14.0 0.0 4.4 6.8 0.0 3.0 3 0 0 3 3 3 0 NmrA-like family DUF268 PF03269.14 GAP85182.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 ENOD40 PF08247.11 GAP85182.1 - 0.13 12.3 0.8 0.47 10.6 0.8 2.0 1 0 0 1 1 1 0 ENOD40 protein GDP_Man_Dehyd PF16363.5 GAP85182.1 - 0.16 11.3 0.0 0.97 8.8 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Methyltransf_12 PF08242.12 GAP85182.1 - 0.18 12.6 0.0 0.59 10.9 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain ANAPC_CDC26 PF10471.9 GAP85183.1 - 0.009 16.8 11.5 0.009 16.8 11.5 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex APC subunit CDC26 DUF4407 PF14362.6 GAP85183.1 - 0.11 11.8 7.0 1.6 8.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SOG2 PF10428.9 GAP85183.1 - 0.4 9.8 20.4 0.47 9.6 20.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein UPF0560 PF10577.9 GAP85183.1 - 2 6.8 15.0 14 4.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 TERB2 PF15101.6 GAP85183.1 - 2.5 8.1 8.7 5.3 7.1 8.7 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ndc1_Nup PF09531.10 GAP85183.1 - 6.3 5.4 14.7 9.1 4.8 14.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Paralemmin PF03285.15 GAP85183.1 - 7 6.1 12.5 6.2 6.3 0.2 2.3 2 0 0 2 2 2 0 Paralemmin eIF-3_zeta PF05091.12 GAP85183.1 - 7.4 5.4 10.7 0.72 8.8 6.5 1.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) OmpH PF03938.14 GAP85183.1 - 8.5 6.7 23.2 3.7 7.9 1.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2236 PF09995.9 GAP85185.1 - 2.3e-34 119.6 7.2 3.6e-34 118.9 7.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Lgl_C PF08596.10 GAP85186.1 - 2.5e-114 382.1 0.0 3.6e-114 381.5 0.0 1.2 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal Glyco_hydro_3_C PF01915.22 GAP85186.1 - 4e-47 160.8 0.1 6.7e-47 160.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAP85186.1 - 1.5e-41 142.9 0.0 2.2e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAP85186.1 - 2.9e-17 62.6 0.4 1.1e-16 60.6 0.1 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain WD40 PF00400.32 GAP85186.1 - 0.0039 18.0 6.3 0.15 12.9 0.1 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Mito_carr PF00153.27 GAP85187.1 - 3e-41 139.2 0.5 1.1e-15 57.3 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.23 GAP85188.1 - 9.8e-58 195.5 0.0 2.1e-57 194.4 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 GAP85188.1 - 5.5e-55 186.3 0.6 1.8e-54 184.6 1.1 1.7 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 GAP85188.1 - 9.9e-15 54.8 0.0 3.2e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP85188.1 - 3e-08 33.9 0.0 5.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 GAP85188.1 - 0.0032 16.7 0.0 0.013 14.7 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 GAP85188.1 - 0.077 12.7 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Sel1 PF08238.12 GAP85189.1 - 3.1e-15 56.3 28.8 8.2e-08 32.7 0.1 7.2 7 0 0 7 7 7 3 Sel1 repeat TPR_2 PF07719.17 GAP85189.1 - 0.022 14.8 1.3 1 9.6 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAP85189.1 - 0.053 14.4 2.2 6.8 7.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAP85189.1 - 0.11 12.3 0.2 0.11 12.3 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAP85189.1 - 1.2 9.5 5.5 0.43 10.9 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAP85189.1 - 1.7 9.5 7.0 0.55 11.0 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 GAP85190.1 - 1.4e-19 70.5 0.0 2.4e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 GAP85190.1 - 0.0044 16.4 0.0 0.0059 16.0 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Coatomer_WDAD PF04053.14 GAP85191.1 - 4.6e-148 494.0 0.1 7.8e-148 493.2 0.0 1.4 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 GAP85191.1 - 3.8e-98 328.9 0.0 5.3e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 GAP85191.1 - 3.9e-37 125.6 21.0 1.8e-07 31.7 0.3 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP85191.1 - 6.3e-06 26.4 0.5 0.97 9.8 0.0 5.4 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 GAP85191.1 - 0.064 13.1 0.2 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS Glyco_transf_24 PF18404.1 GAP85192.1 - 1e-148 494.0 3.7 1.6e-148 493.3 3.7 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 GAP85192.1 - 2.9e-69 233.9 0.1 7.4e-68 229.3 0.0 2.6 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 GAP85192.1 - 3.9e-52 177.3 0.1 5e-51 173.6 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 GAP85192.1 - 1.4e-46 158.8 0.1 3.9e-45 154.1 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 GAP85192.1 - 4.2e-41 139.5 0.0 8e-41 138.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 GAP85192.1 - 5.6e-40 136.4 0.4 2.5e-39 134.3 0.0 2.3 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 GAP85192.1 - 0.0001 21.9 0.2 0.00021 20.9 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_2 PF00891.18 GAP85193.1 - 3.4e-22 78.8 0.0 5.5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FAD_binding_4 PF01565.23 GAP85194.1 - 1.5e-26 92.8 0.2 3.9e-26 91.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain UbiA PF01040.18 GAP85195.1 - 2.7e-43 148.1 15.5 2.7e-43 148.1 15.5 1.8 1 1 1 2 2 2 2 UbiA prenyltransferase family adh_short PF00106.25 GAP85196.1 - 4.5e-18 65.4 0.1 1.7e-17 63.5 0.0 1.9 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP85196.1 - 9.5e-10 38.4 0.1 3.2e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP85196.1 - 3e-06 27.3 0.0 5.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP85196.1 - 0.085 12.3 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family OPT PF03169.15 GAP85197.1 - 0.038 12.6 0.1 0.046 12.4 0.1 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein p450 PF00067.22 GAP85198.1 - 1.2e-26 93.5 0.1 3e-22 79.0 0.2 3.2 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 GAP85200.1 - 1.3e-48 166.0 0.0 1.7e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.29 GAP85202.1 - 1.6e-17 64.2 0.0 3.3e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP85202.1 - 8.1e-06 26.3 0.9 0.00038 20.9 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain Zot PF05707.12 GAP85202.1 - 0.00011 21.9 0.2 0.0012 18.5 0.1 2.3 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_5 PF07728.14 GAP85202.1 - 0.0012 18.9 0.0 0.0034 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP85202.1 - 0.0013 19.0 0.4 0.045 14.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain Laminin_II PF06009.12 GAP85202.1 - 0.12 12.3 0.6 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain II RFXA_RFXANK_bdg PF15289.6 GAP85202.1 - 1.3 9.3 5.5 3.2 8.1 5.5 1.6 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Ribosomal_60s PF00428.19 GAP85203.1 - 0.013 16.1 7.2 0.013 16.1 7.2 3.3 2 1 0 2 2 2 0 60s Acidic ribosomal protein TFIIE-A_C PF11521.8 GAP85203.1 - 1.4 9.3 6.4 9.6 6.6 0.3 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Importin_rep_4 PF18808.1 GAP85204.1 - 5.3e-30 103.6 1.6 5.3e-30 103.6 1.6 4.9 6 0 0 6 6 5 1 Importin repeat HEAT_EZ PF13513.6 GAP85204.1 - 2.3e-23 82.3 11.9 2.2e-10 40.8 0.1 8.8 7 1 2 9 9 8 3 HEAT-like repeat Importin_rep_5 PF18816.1 GAP85204.1 - 1.5e-19 70.0 3.7 2.9e-19 69.1 0.6 3.1 3 0 0 3 3 3 1 Importin repeat HEAT PF02985.22 GAP85204.1 - 4.9e-14 51.2 12.8 0.0071 16.5 0.0 10.1 10 0 0 10 10 9 2 HEAT repeat HEAT_2 PF13646.6 GAP85204.1 - 7.2e-14 51.9 14.5 2.8e-05 24.4 0.0 8.1 4 2 4 8 8 8 3 HEAT repeats Importin_rep_6 PF18829.1 GAP85204.1 - 1.1e-11 44.8 2.8 3.5e-11 43.2 0.2 3.0 3 0 0 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 GAP85204.1 - 2.5e-11 44.0 0.0 0.0058 17.2 0.0 6.0 4 1 3 7 7 6 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 GAP85204.1 - 4.3e-09 36.4 0.0 0.00022 21.0 0.0 4.4 3 1 1 4 4 4 3 rRNA processing/ribosome biogenesis DRIM PF07539.12 GAP85204.1 - 1.4e-07 30.3 0.7 0.001 17.5 0.1 3.8 2 1 1 3 3 3 2 Down-regulated in metastasis DUF3385 PF11865.8 GAP85204.1 - 6.7e-07 29.4 0.8 0.045 13.6 0.0 5.5 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 GAP85204.1 - 9.7e-07 28.2 4.1 1.8e-06 27.3 0.1 3.2 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 GAP85204.1 - 1.7e-05 24.9 0.2 0.039 14.0 0.0 4.8 5 2 1 6 6 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 GAP85204.1 - 0.00014 21.6 0.4 0.0048 16.5 0.0 3.5 3 1 1 4 4 4 1 CLASP N terminal IBN_N PF03810.19 GAP85204.1 - 0.00019 21.3 0.1 0.0015 18.4 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 GAP85204.1 - 0.0021 18.2 0.2 0.18 12.0 0.2 3.6 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 GAP85204.1 - 0.0028 17.6 4.7 3.2 7.7 0.2 3.9 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Adaptin_N PF01602.20 GAP85204.1 - 0.0032 16.1 1.6 0.18 10.3 0.3 3.0 1 1 2 3 3 3 2 Adaptin N terminal region Telomere_reg-2 PF10193.9 GAP85204.1 - 0.0033 17.9 2.6 0.02 15.3 0.6 3.2 3 0 0 3 3 3 1 Telomere length regulation protein Cnd3 PF12719.7 GAP85204.1 - 0.0093 15.2 0.0 0.09 12.0 0.0 2.6 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain TFCD_C PF12612.8 GAP85204.1 - 0.026 14.4 0.1 2.5 7.9 0.0 3.3 2 1 1 3 3 3 0 Tubulin folding cofactor D C terminal V-ATPase_H_N PF03224.14 GAP85204.1 - 0.035 13.4 0.7 0.2 10.9 0.0 2.6 3 1 1 4 4 4 0 V-ATPase subunit H DNA_alkylation PF08713.11 GAP85204.1 - 0.045 13.5 0.5 0.4 10.4 0.1 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme Arm PF00514.23 GAP85204.1 - 0.2 11.8 11.9 4.8 7.4 0.0 6.0 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat Antimicrobial_4 PF08024.11 GAP85204.1 - 0.29 11.2 0.8 0.69 10.0 0.8 1.6 1 0 0 1 1 1 0 Ant antimicrobial peptide Pyr_redox_2 PF07992.14 GAP85205.1 - 5.5e-41 140.7 0.5 7.6e-41 140.3 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP85205.1 - 5.2e-12 46.2 1.8 3.2e-10 40.4 0.7 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP85205.1 - 6.4e-05 22.7 2.9 0.78 9.2 0.0 4.0 2 1 2 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAP85205.1 - 0.00028 20.1 0.0 0.0044 16.2 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 GAP85205.1 - 0.00085 18.3 1.6 4 6.2 0.0 3.2 2 1 1 3 3 3 2 Tryptophan halogenase DUF4147 PF13660.6 GAP85205.1 - 0.0015 18.1 0.1 0.23 10.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4147) Lycopene_cycl PF05834.12 GAP85205.1 - 0.0019 17.4 0.8 0.28 10.2 0.1 3.2 4 0 0 4 4 4 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAP85205.1 - 0.0022 17.3 0.0 0.02 14.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP85205.1 - 0.0048 17.1 0.1 0.48 10.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAP85205.1 - 0.0052 15.9 2.6 0.29 10.1 0.2 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAP85205.1 - 0.0061 15.7 0.2 1.3 8.0 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain Pribosyltran PF00156.27 GAP85205.1 - 0.028 13.9 0.0 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Thi4 PF01946.17 GAP85205.1 - 0.037 13.3 0.0 0.33 10.2 0.0 2.2 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 GAP85205.1 - 0.046 13.0 2.3 0.83 8.9 0.3 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 GAP85205.1 - 0.048 12.4 1.3 0.72 8.5 0.1 3.0 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 GAP85205.1 - 0.052 13.5 1.8 86 3.1 0.0 4.6 4 1 0 5 5 5 0 FAD-NAD(P)-binding CheB_methylest PF01339.17 GAP85205.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 CheB methylesterase FAD_oxidored PF12831.7 GAP85205.1 - 0.17 11.2 1.4 3.1 7.0 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase CBS PF00571.28 GAP85206.1 - 7.1e-17 61.6 6.4 0.00014 22.2 0.1 5.3 5 1 0 5 5 5 4 CBS domain Mog1 PF04603.12 GAP85207.1 - 2.2e-35 122.0 0.0 2.9e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.9 GAP85208.1 - 1e-27 96.2 0.1 2.4e-27 95.0 0.1 1.7 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 GAP85208.1 - 1.4e-07 31.3 3.4 2.5e-07 30.5 3.4 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Glucan_synthase PF02364.15 GAP85209.1 - 0 1359.3 0.0 0 1358.7 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 GAP85209.1 - 2e-42 144.6 0.1 8.2e-42 142.6 0.1 2.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Abhydrolase_1 PF00561.20 GAP85211.1 - 4.1e-07 29.9 0.3 1.2e-05 25.1 0.2 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP85211.1 - 9.5e-06 25.0 0.2 0.0026 17.1 0.2 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 DUF3246 PF11596.8 GAP85211.1 - 1.6 8.1 3.1 22 4.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) RTA1 PF04479.13 GAP85212.1 - 9.1e-40 136.5 6.3 1.3e-39 136.0 6.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DEAD PF00270.29 GAP85213.1 - 2.5e-46 157.6 0.0 3.6e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP85213.1 - 4.1e-31 107.6 0.0 1.5e-30 105.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP85213.1 - 2.1e-05 24.6 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAP85213.1 - 0.0049 17.2 0.0 0.0086 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Bystin PF05291.11 GAP85215.1 - 2.2e-116 388.2 0.0 2.8e-116 387.9 0.0 1.1 1 0 0 1 1 1 1 Bystin Rsa3 PF14615.6 GAP85216.1 - 8.9e-22 76.4 0.3 1.2e-21 76.0 0.3 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Ytp1 PF10355.9 GAP85217.1 - 7.6e-117 389.4 4.6 7.6e-117 389.4 4.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 GAP85217.1 - 2.9e-31 107.4 4.9 2.9e-31 107.4 4.9 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) DUF5504 PF17608.2 GAP85217.1 - 0.22 11.6 5.9 0.53 10.4 2.7 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5504) Ca_hom_mod PF14798.6 GAP85217.1 - 0.26 10.3 1.3 0.45 9.6 0.0 2.0 2 0 0 2 2 2 0 Calcium homeostasis modulator Lactamase_B PF00753.27 GAP85218.1 - 1.1e-17 64.7 4.7 2e-15 57.3 4.7 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 GAP85218.1 - 1.1e-16 60.6 0.2 2.5e-16 59.4 0.2 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 GAP85218.1 - 1.1e-05 25.1 1.0 3.5e-05 23.4 0.8 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain DinB_2 PF12867.7 GAP85218.1 - 0.027 15.0 0.4 0.047 14.2 0.4 1.7 1 1 0 1 1 1 0 DinB superfamily UCH PF00443.29 GAP85219.1 - 9.5e-49 166.2 1.8 1.3e-48 165.8 1.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAP85219.1 - 1e-29 104.2 4.6 1e-29 104.2 4.6 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAP85219.1 - 0.00033 20.9 0.2 0.00033 20.9 0.2 2.5 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein TF_Zn_Ribbon PF08271.12 GAP85219.1 - 0.079 12.5 8.5 2.2 7.9 0.1 4.2 3 1 1 4 4 4 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 GAP85219.1 - 0.27 11.2 5.7 0.89 9.5 0.2 2.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain N6-adenineMlase PF10237.9 GAP85220.1 - 2.5e-47 160.7 0.0 3.1e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase DUF3446 PF11928.8 GAP85220.1 - 0.042 14.1 2.0 0.042 14.1 2.0 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 GAP85220.1 - 1.4 8.5 6.3 2 7.9 6.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NmrA PF05368.13 GAP85221.1 - 2.9e-15 56.5 0.0 4.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP85221.1 - 4.3e-15 56.1 0.0 6.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP85221.1 - 6.2e-13 48.8 0.1 1.4e-12 47.6 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAP85221.1 - 3.7e-09 36.0 0.0 6.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAP85221.1 - 2.3e-07 30.6 0.4 1.2e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAP85221.1 - 4.1e-07 29.4 0.0 5.7e-06 25.6 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 GAP85221.1 - 9.3e-06 25.2 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP85221.1 - 0.0005 19.7 0.0 0.00084 19.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 GAP85221.1 - 0.024 13.8 0.1 0.95 8.6 0.0 2.4 1 1 2 3 3 3 0 Male sterility protein KR PF08659.10 GAP85221.1 - 0.057 13.3 0.0 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 GAP85221.1 - 0.15 11.2 0.0 0.29 10.2 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein PCI PF01399.27 GAP85222.1 - 0.083 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 PCI domain Gaa1 PF04114.14 GAP85223.1 - 9.1e-164 546.1 0.2 1.1e-163 545.9 0.2 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 GAP85224.1 - 2e-11 44.1 12.0 2e-11 44.1 12.0 1.6 2 0 0 2 2 2 1 Rhomboid family 5TM-5TMR_LYT PF07694.12 GAP85224.1 - 0.0057 16.2 5.0 0.0057 16.2 5.0 1.9 2 0 0 2 2 2 1 5TMR of 5TMR-LYT Aconitase PF00330.20 GAP85225.1 - 4.2e-148 494.2 0.0 5.3e-148 493.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAP85225.1 - 5.6e-43 146.4 0.0 9.6e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 GAP85226.1 - 1.1e-09 38.4 0.1 1.9e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP85226.1 - 0.021 15.2 0.1 0.043 14.2 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAP85226.1 - 0.099 13.0 0.2 0.17 12.2 0.2 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DASH_Dam1 PF08653.10 GAP85227.1 - 2.7e-27 94.3 0.9 3.6e-27 93.9 0.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 RT_RNaseH PF17917.1 GAP85228.1 - 2.4e-15 56.7 0.0 6.1e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 GAP85228.1 - 8.9e-15 54.6 0.0 1.9e-07 31.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 GAP85228.1 - 4.3e-07 29.7 0.0 9.3e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 GAP85228.1 - 1.6e-06 28.3 0.0 4.6e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 GAP85228.1 - 0.0011 19.0 0.2 0.0037 17.3 0.0 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain zf-C2H2 PF00096.26 GAP85228.1 - 1.9 9.1 5.6 9.8 6.9 5.6 2.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP85228.1 - 3.5 8.7 9.2 0.86 10.6 4.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger CRAL_TRIO PF00650.20 GAP85229.1 - 6.5e-39 133.2 0.0 1.1e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAP85229.1 - 1.4e-11 44.3 0.1 3.9e-11 43.0 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAP85229.1 - 9.1e-08 32.3 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TP53IP5 PF15331.6 GAP85229.1 - 0.65 10.1 5.0 0.91 9.6 0.2 2.5 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 HIT PF01230.23 GAP85230.1 - 1.7e-21 76.7 0.1 2.4e-21 76.3 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAP85230.1 - 6.2e-11 42.8 0.0 8.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 GAP85230.1 - 1.4e-05 24.9 0.0 2.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Gelsolin PF00626.22 GAP85231.1 - 1.4e-33 114.6 0.1 2e-10 40.4 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Aminotran_1_2 PF00155.21 GAP85232.1 - 7.7e-38 130.6 0.0 9.2e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAP85232.1 - 0.03 12.8 0.0 0.068 11.7 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF3755 PF12579.8 GAP85232.1 - 1.1 9.0 2.9 0.48 10.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) Glyco_hydro_17 PF00332.18 GAP85233.1 - 2.7e-07 30.5 0.3 8e-07 28.9 0.1 1.8 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 Inp1 PF12634.7 GAP85234.1 - 1.1e-38 132.4 0.0 2.9e-38 131.0 0.0 1.8 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Beta_elim_lyase PF01212.21 GAP85236.1 - 1.4e-65 221.5 0.0 2.2e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Trp_DMAT PF11991.8 GAP85236.1 - 5.3e-13 49.1 0.0 3e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase ATPase_2 PF01637.18 GAP85237.1 - 0.019 14.9 0.6 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 GAP85237.1 - 0.052 13.8 0.3 30 4.9 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 GAP85237.1 - 0.073 13.6 0.1 0.26 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 GAP85237.1 - 0.083 12.9 0.0 0.58 10.1 0.0 2.1 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit zf-CCHC_4 PF14392.6 GAP85238.1 - 1.5e-05 24.6 30.2 0.12 12.1 0.7 5.1 4 1 1 5 5 5 4 Zinc knuckle NPV_P10 PF05531.12 GAP85239.1 - 0.0043 17.5 22.4 2.2 8.8 0.5 6.1 2 1 4 6 6 6 2 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.10 GAP85239.1 - 0.038 13.8 8.9 3.6 7.4 0.4 5.0 5 1 1 6 6 6 0 DASH complex subunit Duo1 FolB PF02152.18 GAP85239.1 - 0.04 14.5 0.3 0.2 12.2 0.3 2.1 2 0 0 2 2 2 0 Dihydroneopterin aldolase Prominin PF05478.11 GAP85239.1 - 0.29 9.0 12.6 0.015 13.3 6.4 1.7 2 0 0 2 2 2 0 Prominin APG6_N PF17675.1 GAP85239.1 - 0.5 10.9 19.4 0.57 10.7 3.8 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Pneumovirus_M2 PF06436.11 GAP85239.1 - 0.67 9.4 4.2 1.1 8.7 0.4 2.3 2 0 0 2 2 2 0 Pneumovirus matrix protein 2 (M2) DUF745 PF05335.13 GAP85239.1 - 1.1 8.9 11.0 1.6 8.4 1.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF745) CCDC-167 PF15188.6 GAP85239.1 - 1.4 9.4 16.8 8.4 6.8 0.6 4.9 3 2 2 5 5 5 0 Coiled-coil domain-containing protein 167 XhlA PF10779.9 GAP85239.1 - 1.9 8.7 13.6 2.2 8.5 0.6 5.3 4 1 2 6 6 6 0 Haemolysin XhlA Laminin_II PF06009.12 GAP85239.1 - 3.1 7.8 16.0 0.77 9.8 0.4 3.6 4 0 0 4 4 4 0 Laminin Domain II DUF1664 PF07889.12 GAP85239.1 - 3.4 7.7 21.3 6.5 6.8 0.4 5.2 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 GAP85239.1 - 4.1 7.6 22.5 2.5 8.3 3.8 3.7 2 1 0 3 3 3 0 JNK_SAPK-associated protein-1 THOC7 PF05615.13 GAP85239.1 - 4.4 7.6 14.6 8.9 6.6 1.4 3.5 3 0 0 3 3 3 0 Tho complex subunit 7 LPP PF04728.13 GAP85239.1 - 7.4 7.0 11.8 40 4.7 1.9 5.1 4 1 1 5 5 5 0 Lipoprotein leucine-zipper COG5 PF10392.9 GAP85239.1 - 7.5 6.7 8.2 26 5.0 1.0 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Lebercilin PF15619.6 GAP85240.1 - 3.5 7.3 8.9 1.1 8.8 2.3 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DnaJ-X PF14308.6 GAP85241.1 - 3.1e-75 252.2 1.2 3.1e-75 252.2 1.2 2.1 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 GAP85241.1 - 1.2e-25 89.4 0.7 3e-25 88.1 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain Peptidase_S8 PF00082.22 GAP85242.1 - 2.9e-06 26.8 0.1 8e-06 25.3 0.1 1.7 1 1 0 1 1 1 1 Subtilase family WD40 PF00400.32 GAP85244.1 - 7.3e-55 181.7 29.8 9e-08 32.7 0.4 11.3 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP85244.1 - 1.6e-23 82.8 0.5 0.00093 19.4 0.0 9.3 6 4 3 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain NACHT_N PF17100.5 GAP85244.1 - 1.3e-17 64.4 0.0 4.1e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Ge1_WD40 PF16529.5 GAP85244.1 - 2.7e-13 49.6 0.0 0.0097 14.9 0.0 6.1 3 2 2 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAP85244.1 - 2.9e-07 30.2 2.1 4.1 7.4 0.0 7.1 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 GAP85244.1 - 0.0038 15.9 0.0 5.2 5.6 0.0 3.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 VID27 PF08553.10 GAP85244.1 - 0.0054 15.8 0.0 2.5 7.0 0.0 2.4 2 0 0 2 2 2 2 VID27 C-terminal WD40-like domain Proteasome_A_N PF10584.9 GAP85244.1 - 0.024 14.3 4.3 36 4.2 0.0 5.6 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature HNH_2 PF13391.6 GAP85245.1 - 8.5e-09 35.4 0.2 2e-08 34.2 0.2 1.7 1 0 0 1 1 1 1 HNH endonuclease RmlD_sub_bind PF04321.17 GAP85246.1 - 5.5e-15 55.2 0.0 2.5e-14 53.1 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 GAP85246.1 - 4.8e-12 45.8 0.0 8.3e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAP85246.1 - 0.00037 19.7 0.0 0.00072 18.8 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAP85246.1 - 0.00039 19.9 0.0 0.00086 18.8 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAP85246.1 - 0.041 12.9 0.1 0.11 11.5 0.0 1.5 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family C2-set_2 PF08205.12 GAP85246.1 - 0.08 13.0 0.2 0.17 12.0 0.2 1.6 1 1 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Aminotran_3 PF00202.21 GAP85247.1 - 3.9e-11 42.3 0.0 5.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAP85247.1 - 0.0011 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Tyrosinase PF00264.20 GAP85248.1 - 7.2e-54 183.4 0.8 1.2e-53 182.6 0.8 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 GAP85248.1 - 4.7e-20 72.5 0.0 9.8e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain Gal-bind_lectin PF00337.22 GAP85248.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Galactoside-binding lectin AMP-binding PF00501.28 GAP85249.1 - 2.2e-65 220.9 0.0 2.9e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP85249.1 - 0.025 15.6 0.0 0.051 14.6 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 GAP85250.1 - 1.7e-16 60.1 0.1 3.1e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85250.1 - 5.9e-08 32.7 7.0 1.1e-07 31.9 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SKA1 PF07160.12 GAP85250.1 - 1.9 8.3 7.5 4.4 7.1 1.9 3.3 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 1 NIF PF03031.18 GAP85251.1 - 4.4e-37 127.3 0.0 6.8e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Esterase_phd PF10503.9 GAP85252.1 - 3.5e-05 23.4 0.1 7.6e-05 22.3 0.1 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 GAP85252.1 - 0.00062 19.3 0.1 0.0018 17.8 0.2 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 GAP85252.1 - 0.0016 18.1 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 GAP85252.1 - 0.16 10.6 0.1 0.32 9.6 0.0 1.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF3173 PF11372.8 GAP85253.1 - 0.21 11.5 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) RNase_PH PF01138.21 GAP85254.1 - 1e-30 106.9 0.1 2e-30 106.0 0.1 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Herpes_capsid PF06112.11 GAP85254.1 - 4.9 7.2 8.8 0.79 9.8 4.4 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Thioredoxin PF00085.20 GAP85255.1 - 3.6e-32 110.4 0.0 4.6e-27 94.0 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 GAP85255.1 - 1.2e-08 34.7 0.0 1.4e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GAP85255.1 - 2.2e-07 31.3 0.2 0.0036 17.8 0.1 2.7 1 1 1 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 GAP85255.1 - 6.4e-05 22.9 0.5 0.0057 16.6 0.0 3.0 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_8 PF13905.6 GAP85255.1 - 8.2e-05 22.9 0.0 0.27 11.6 0.0 3.6 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 GAP85255.1 - 0.0013 18.9 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like QSOX_Trx1 PF18108.1 GAP85255.1 - 0.0056 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 QSOX Trx-like domain HyaE PF07449.11 GAP85255.1 - 0.011 15.6 0.0 3.3 7.7 0.0 2.8 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 GAP85255.1 - 0.022 14.8 0.1 0.55 10.3 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin domain MIF PF01187.18 GAP85255.1 - 0.1 12.9 0.7 0.34 11.2 0.1 2.0 2 0 0 2 2 2 0 Macrophage migration inhibitory factor (MIF) TraF PF13728.6 GAP85255.1 - 0.11 12.3 11.0 0.13 12.1 0.0 3.5 3 1 0 3 3 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 GAP85255.1 - 0.13 12.5 1.9 0.46 10.7 0.0 2.5 3 0 0 3 3 2 0 Glutaredoxin Vta1 PF04652.16 GAP85256.1 - 8.1e-54 181.5 1.4 1.6e-53 180.6 0.6 1.7 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 GAP85256.1 - 2.7e-17 62.1 0.2 2.7e-17 62.1 0.2 1.6 2 0 0 2 2 2 1 Vta1 C-terminal domain adh_short_C2 PF13561.6 GAP85257.1 - 6.1e-52 176.5 5.7 3.7e-50 170.7 5.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP85257.1 - 1.4e-45 155.2 0.5 3.1e-45 154.0 0.5 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP85257.1 - 2.6e-14 53.5 1.0 2.6e-14 53.5 1.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAP85257.1 - 0.0036 16.8 0.1 0.0092 15.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CAP PF00188.26 GAP85258.1 - 4.5e-06 27.5 0.4 5.8e-06 27.1 0.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 GAP85259.1 - 1.8e-05 25.6 0.1 2.5e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_hydro_43 PF04616.14 GAP85260.1 - 9.3e-33 113.8 7.7 1.1e-32 113.5 7.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Herpes_heli_pri PF05774.11 GAP85260.1 - 0.1 12.8 0.3 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus helicase-primase complex component TRI12 PF06609.13 GAP85261.1 - 7.6e-72 242.6 22.2 1e-71 242.2 22.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAP85261.1 - 4e-27 95.1 52.2 5.2e-26 91.4 48.4 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP85261.1 - 7.4e-10 38.3 6.2 7.4e-10 38.3 6.2 3.3 2 1 2 4 4 4 1 Sugar (and other) transporter ECH_1 PF00378.20 GAP85262.1 - 4.1e-58 196.6 0.0 5.5e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAP85262.1 - 7.8e-26 91.3 0.1 4.4e-23 82.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 GAP85263.1 - 2.7e-38 131.7 0.1 3.4e-38 131.3 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ABC_tran PF00005.27 GAP85264.1 - 5.2e-34 117.7 0.0 1e-33 116.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 GAP85264.1 - 1.4e-33 116.7 12.0 1.4e-33 116.7 12.0 1.5 2 0 0 2 2 1 1 ABC transporter transmembrane region SMC_N PF02463.19 GAP85264.1 - 4.4e-05 23.0 0.3 0.0026 17.2 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAP85264.1 - 0.00053 20.3 0.2 0.0023 18.2 0.2 1.9 1 1 0 1 1 1 1 AAA domain MTABC_N PF16185.5 GAP85264.1 - 0.0033 17.0 1.8 0.0081 15.7 0.0 2.4 3 0 0 3 3 3 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_10 PF12846.7 GAP85264.1 - 0.0041 16.1 0.1 0.0083 15.1 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.6 GAP85264.1 - 0.0046 16.7 0.3 0.016 14.9 0.3 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 GAP85264.1 - 0.013 15.9 1.2 0.16 12.3 1.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 GAP85264.1 - 0.061 13.6 0.3 0.53 10.6 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 GAP85264.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 GAP85264.1 - 0.1 12.4 0.3 0.63 9.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Ank_4 PF13637.6 GAP85266.1 - 3.6e-10 40.2 0.1 6.8e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP85266.1 - 1.9e-08 34.4 0.1 0.00049 20.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP85266.1 - 1.1e-07 31.5 0.0 0.016 15.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 GAP85266.1 - 1.5e-07 31.9 0.0 2.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAP85266.1 - 0.0041 17.5 0.2 2.5 8.7 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeat Mo25 PF08569.11 GAP85266.1 - 0.0083 15.5 0.2 0.014 14.8 0.2 1.3 1 0 0 1 1 1 1 Mo25-like bZIP_1 PF00170.21 GAP85266.1 - 0.014 15.5 6.9 0.03 14.4 6.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor Nop25 PF09805.9 GAP85266.1 - 0.022 15.2 0.4 0.034 14.6 0.4 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) HR1 PF02185.16 GAP85266.1 - 0.075 13.2 3.1 0.15 12.2 3.1 1.4 1 0 0 1 1 1 0 Hr1 repeat PSD5 PF07637.11 GAP85266.1 - 0.1 12.9 0.3 0.22 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) PHC2_SAM_assoc PF16616.5 GAP85266.1 - 4.5 8.1 7.2 0.48 11.2 2.5 1.8 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 RCDG1 PF15725.5 GAP85267.1 - 0.13 12.7 1.7 0.24 11.8 1.7 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Pkinase PF00069.25 GAP85269.1 - 4.2e-33 114.8 0.0 5.9e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP85269.1 - 6.3e-17 61.7 0.0 9.9e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP85269.1 - 0.0046 16.3 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CAP_N PF01213.19 GAP85271.1 - 0.023 14.2 4.6 0.028 13.9 4.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 GAP85271.1 - 0.06 13.4 1.2 0.06 13.4 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 GAP85271.1 - 3.2 7.8 6.3 4.9 7.2 6.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 GrpB PF04229.14 GAP85272.1 - 4.8e-51 173.1 0.0 5.6e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 GrpB protein His_Phos_1 PF00300.22 GAP85272.1 - 0.041 13.6 1.3 4.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) Amidase PF01425.21 GAP85274.1 - 9.7e-46 156.6 0.4 1.5e-45 156.0 0.4 1.4 1 1 0 1 1 1 1 Amidase Oxidored_FMN PF00724.20 GAP85275.1 - 6.1e-89 298.6 0.0 7e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NACHT PF05729.12 GAP85276.1 - 4e-08 33.4 0.0 1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP85276.1 - 7.9e-07 29.6 0.2 5.2e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 GAP85276.1 - 2.4e-06 27.6 0.6 3 7.9 0.0 4.8 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.6 GAP85276.1 - 0.0018 18.8 0.1 0.0075 16.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain HTH_20 PF12840.7 GAP85276.1 - 0.0081 16.2 0.1 0.055 13.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain WD40 PF00400.32 GAP85276.1 - 0.017 16.0 0.0 0.058 14.3 0.0 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat HTH_5 PF01022.20 GAP85276.1 - 0.018 14.9 0.2 0.077 12.9 0.2 2.1 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TPR_MLP1_2 PF07926.12 GAP85276.1 - 0.02 14.9 0.1 0.047 13.7 0.1 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein NB-ARC PF00931.22 GAP85276.1 - 0.022 13.9 0.0 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 GAP85276.1 - 0.025 14.8 0.1 0.32 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAP85276.1 - 0.049 14.0 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 GAP85276.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 GAP85276.1 - 0.12 12.0 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 GAP85276.1 - 1.1 8.4 3.4 3.9 6.6 0.7 2.4 1 1 1 2 2 2 0 KAP family P-loop domain Fungal_trans_2 PF11951.8 GAP85277.1 - 1.8e-23 83.0 0.0 4.4e-17 62.0 0.0 2.6 1 1 1 2 2 2 2 Fungal specific transcription factor domain Thi4 PF01946.17 GAP85277.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Spt20 PF12090.8 GAP85277.1 - 1.7 8.2 5.3 2.6 7.6 5.3 1.2 1 0 0 1 1 1 0 Spt20 family Cwf_Cwc_15 PF04889.12 GAP85277.1 - 4.1 7.1 14.1 6.4 6.4 14.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPR_1 PF00515.28 GAP85278.1 - 1.6e-48 160.7 14.7 2e-06 27.3 0.2 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 GAP85278.1 - 2.7e-40 133.2 13.2 5.5e-07 29.2 0.1 10.0 10 0 0 10 10 10 9 Tetratricopeptide repeat STI1 PF17830.1 GAP85278.1 - 4.2e-34 116.3 11.3 1.1e-18 66.9 0.4 2.9 3 0 0 3 3 3 2 STI1 domain TPR_11 PF13414.6 GAP85278.1 - 2.5e-24 84.7 11.5 0.00013 21.6 0.0 7.3 6 1 2 8 8 8 6 TPR repeat TPR_8 PF13181.6 GAP85278.1 - 1.6e-22 77.8 14.6 0.00012 22.0 0.2 8.1 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAP85278.1 - 1.8e-18 65.7 1.5 0.018 15.8 0.1 8.1 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAP85278.1 - 1.2e-15 57.8 3.0 0.0015 19.2 0.1 5.9 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 GAP85278.1 - 5.6e-15 55.6 2.1 0.17 12.4 0.0 6.5 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 GAP85278.1 - 2.2e-14 53.5 9.2 1.5e-07 31.6 0.3 6.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP85278.1 - 2e-13 49.3 1.4 0.012 15.6 0.0 7.5 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAP85278.1 - 9.8e-13 48.1 0.0 0.0004 20.5 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAP85278.1 - 2.6e-09 36.8 6.4 1.3 9.6 0.1 8.2 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAP85278.1 - 8.5e-06 25.5 6.4 0.91 9.5 0.1 6.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP85278.1 - 0.00095 19.7 14.0 2.1 9.2 0.0 7.1 9 0 0 9 9 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP85278.1 - 0.0017 18.5 4.2 1.1 9.6 0.7 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 GAP85278.1 - 0.0047 16.4 0.6 6.2 6.4 0.0 4.0 4 0 0 4 4 4 1 SHNi-TPR DUF5113 PF17140.4 GAP85278.1 - 0.017 15.0 5.3 2.9 7.7 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) MIT PF04212.18 GAP85278.1 - 6.2 7.0 18.1 11 6.2 0.1 6.5 7 1 0 7 7 7 0 MIT (microtubule interacting and transport) domain RNA_pol_Rpc34 PF05158.12 GAP85279.1 - 3.4e-81 273.2 0.0 4.3e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 GAP85279.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC GntR PF00392.21 GAP85279.1 - 0.021 14.4 1.0 0.15 11.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_27 PF13463.6 GAP85279.1 - 0.041 14.4 0.0 0.085 13.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain TFIIE_alpha PF02002.17 GAP85279.1 - 0.041 13.7 0.8 0.08 12.8 0.1 1.8 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_36 PF13730.6 GAP85279.1 - 0.063 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 GAP85279.1 - 0.15 12.0 0.1 0.34 10.8 0.1 1.6 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 GAP85279.1 - 0.2 12.1 0.5 5.1 7.5 0.2 2.7 2 1 0 2 2 2 0 Transcriptional regulator Pro_isomerase PF00160.21 GAP85280.1 - 1.9e-45 155.0 0.1 2.1e-45 154.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 GAP85281.1 - 1.8e-45 154.0 0.1 2.8e-45 153.4 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 GAP85281.1 - 0.00054 19.0 0.0 0.00085 18.4 0.0 1.3 1 0 0 1 1 1 1 ANTH domain AF-4 PF05110.13 GAP85282.1 - 0.0018 16.5 10.7 0.0026 15.9 10.7 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein MARVEL PF01284.23 GAP85282.1 - 0.08 13.0 13.0 0.26 11.3 13.0 1.8 1 1 0 1 1 1 0 Membrane-associating domain Apt1 PF10351.9 GAP85282.1 - 0.082 11.8 1.8 0.11 11.3 1.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 GAP85282.1 - 0.78 7.9 5.5 0.97 7.6 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SARAF PF06682.12 GAP85282.1 - 2 8.0 4.6 5.3 6.6 4.6 1.7 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Macoilin PF09726.9 GAP85282.1 - 9.5 4.6 7.3 13 4.2 7.3 1.2 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_12 PF01670.16 GAP85283.1 - 4.6e-20 72.5 4.4 7.5e-20 71.8 4.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 OpcA PF07239.11 GAP85283.1 - 0.085 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Outer membrane protein OpcA UDG PF03167.19 GAP85286.1 - 1.1e-11 45.0 0.0 6e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily UDPGP PF01704.18 GAP85288.1 - 1.6e-49 168.7 0.0 3.5e-48 164.3 0.0 2.0 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 GAP85288.1 - 0.084 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain FAR1 PF03101.15 GAP85289.1 - 0.0024 18.5 0.0 0.0052 17.4 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain Mpv17_PMP22 PF04117.12 GAP85290.1 - 2.7e-25 88.4 1.3 4.4e-25 87.7 1.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family PX PF00787.24 GAP85291.1 - 6.7e-19 68.0 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 PX domain Sulfotransfer_4 PF17784.1 GAP85292.1 - 2.2e-47 161.7 0.0 2.5e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAP85292.1 - 0.032 14.6 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 Sulfotransferase family DUF5445 PF17520.2 GAP85294.1 - 0.28 11.1 1.1 2 8.4 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5445) 2-Hacid_dh_C PF02826.19 GAP85295.1 - 9.8e-42 142.3 0.0 6e-41 139.8 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP85295.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain dsrm PF00035.26 GAP85296.1 - 0.0059 17.3 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Cwf_Cwc_15 PF04889.12 GAP85296.1 - 0.029 14.1 19.2 0.05 13.3 19.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 GAP85296.1 - 0.056 13.5 10.1 0.13 12.3 10.1 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 GAP85296.1 - 0.21 9.6 17.4 0.26 9.3 17.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GAP85296.1 - 0.32 9.1 12.9 0.46 8.6 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 GAP85296.1 - 0.34 11.2 6.4 0.57 10.5 6.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.12 GAP85296.1 - 0.64 9.3 17.0 0.95 8.7 17.0 1.2 1 0 0 1 1 1 0 NOA36 protein Tom22 PF04281.13 GAP85296.1 - 0.67 9.7 8.3 1.2 8.9 8.3 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CDC45 PF02724.14 GAP85296.1 - 0.74 8.0 10.9 1 7.6 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 GAP85296.1 - 1.6 7.3 20.4 0.07 11.7 14.4 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM176 PF14851.6 GAP85296.1 - 2.3 7.9 9.8 5.8 6.6 9.8 1.7 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.11 GAP85296.1 - 3.5 6.0 10.1 4.7 5.6 10.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 GAP85296.1 - 4.6 7.7 19.3 15 6.0 19.3 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Astro_capsid_p PF12226.8 GAP85296.1 - 5 6.2 11.0 7.7 5.6 11.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein adh_short PF00106.25 GAP85297.1 - 4.1e-35 121.0 0.2 4.9e-35 120.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP85297.1 - 1e-31 110.3 0.1 1.2e-31 110.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP85297.1 - 2.3e-09 37.4 0.8 9.6e-09 35.4 0.8 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 GAP85297.1 - 0.1 11.6 0.1 4.4 6.2 0.1 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.22 GAP85298.1 - 2e-42 144.6 0.0 2.8e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP85298.1 - 2.9e-29 101.7 0.0 4e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP85298.1 - 7e-11 41.9 0.0 2.7e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAP85298.1 - 0.00034 20.7 0.0 0.00049 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAP85298.1 - 0.0032 16.9 0.0 0.0041 16.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAP85298.1 - 0.0046 16.5 0.0 0.018 14.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 GAP85298.1 - 0.01 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 GAP85298.1 - 0.018 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAP85298.1 - 0.034 14.1 0.0 0.11 12.4 0.0 1.8 1 1 1 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 GAP85298.1 - 0.046 14.0 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAP85298.1 - 0.053 13.9 0.1 0.091 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAP85298.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GAP85298.1 - 0.08 12.9 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 GAP85298.1 - 0.089 12.5 0.0 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 GAP85298.1 - 0.15 12.6 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 GAP85298.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Mannosidase_ig PF17786.1 GAP85299.1 - 3.1e-12 47.0 0.1 1e-11 45.3 0.0 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 GAP85299.1 - 3.2e-09 37.4 0.0 9.3e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 GAP85299.1 - 8.7e-05 22.2 0.0 0.00022 20.9 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 GAP85299.1 - 0.0041 17.0 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 GAP85299.1 - 0.0083 15.3 0.5 0.025 13.7 0.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cytotoxic PF09000.10 GAP85299.1 - 0.041 14.2 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Cytotoxic ADH_N PF08240.12 GAP85300.1 - 1.2e-28 99.2 1.2 1.3e-28 99.0 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP85300.1 - 2.4e-22 79.3 0.4 4.3e-22 78.5 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAP85300.1 - 3.3e-08 33.3 0.6 5.6e-08 32.5 0.6 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAP85300.1 - 3.7e-07 31.3 0.1 9.5e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 GAP85300.1 - 0.0015 17.8 0.5 0.0032 16.7 0.4 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAP85300.1 - 0.002 17.5 1.6 0.0033 16.8 1.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 GAP85300.1 - 0.0068 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PALP PF00291.25 GAP85300.1 - 0.011 15.2 3.5 0.011 15.2 3.5 1.5 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Pyr_redox PF00070.27 GAP85300.1 - 0.025 15.1 0.3 0.15 12.6 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP85300.1 - 0.045 12.4 1.7 0.065 11.9 1.7 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAP85300.1 - 0.12 11.6 0.3 0.29 10.3 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 GAP85300.1 - 0.2 11.7 1.1 0.39 10.8 1.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GST_N_3 PF13417.6 GAP85301.1 - 6.7e-12 45.6 0.0 1.7e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAP85301.1 - 4.8e-11 42.8 0.1 1.2e-10 41.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAP85301.1 - 0.0017 18.5 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAP85301.1 - 0.0046 17.3 0.0 0.0092 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP85301.1 - 0.0081 16.2 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3160 PF11369.8 GAP85301.1 - 0.071 11.6 0.0 0.097 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) GST_C_5 PF16865.5 GAP85301.1 - 0.17 12.5 0.0 0.28 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Hist_deacetyl PF00850.19 GAP85302.1 - 1.9e-82 277.2 0.0 3.8e-82 276.2 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain Rap1_C PF11626.8 GAP85302.1 - 2.1 8.5 5.7 0.19 11.8 0.6 1.9 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ribosomal_L14 PF00238.19 GAP85303.1 - 2.6e-33 114.7 0.0 3.1e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF5427 PF10310.9 GAP85305.1 - 1.7e-180 601.0 0.0 2e-180 600.8 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 GAP85305.1 - 0.028 14.6 0.2 0.078 13.2 0.2 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain SARAF PF06682.12 GAP85305.1 - 0.18 11.4 3.6 0.32 10.6 3.6 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Malic_M PF03949.15 GAP85306.1 - 1.6e-84 283.2 0.0 2.5e-84 282.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 GAP85306.1 - 2.4e-66 223.0 0.0 4.4e-66 222.1 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF1996 PF09362.10 GAP85307.1 - 7.5e-82 274.8 2.8 9.1e-82 274.6 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1660 PF07874.11 GAP85307.1 - 0.037 14.5 1.2 11 6.6 0.0 2.8 3 0 0 3 3 3 0 Prophage protein (DUF1660) RIFIN PF02009.16 GAP85309.1 - 0.35 10.7 0.0 0.55 10.1 0.0 1.2 1 0 0 1 1 1 0 Rifin Syndecan PF01034.20 GAP85309.1 - 0.36 10.8 2.5 0.82 9.6 2.5 1.5 1 0 0 1 1 1 0 Syndecan domain GRDP-like PF07173.12 GAP85310.1 - 9.5e-21 74.9 0.2 7.3e-13 49.4 0.0 2.6 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Lar_restr_allev PF14354.6 GAP85310.1 - 0.001 19.4 1.5 0.0031 17.9 0.1 2.5 2 0 0 2 2 2 1 Restriction alleviation protein Lar CpXC PF14353.6 GAP85310.1 - 0.043 13.9 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 CpXC protein Atg14 PF10186.9 GAP85312.1 - 4e-11 42.6 8.3 4e-11 42.6 8.3 2.9 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 GAP85312.1 - 3.2e-10 39.5 0.1 2.3e-06 26.8 0.0 2.7 3 0 0 3 3 3 2 Vacuolar protein sorting 38 HrpB2 PF09487.10 GAP85312.1 - 0.027 14.9 1.0 0.059 13.8 1.0 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Apq12 PF12716.7 GAP85313.1 - 0.17 11.8 2.2 0.33 10.9 2.2 1.4 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Glyco_hydro_115 PF15979.5 GAP85314.1 - 1.3e-140 468.6 0.7 6e-140 466.5 0.6 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 GAP85314.1 - 1.8e-47 161.4 0.0 3e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Kinesin PF00225.23 GAP85315.1 - 5e-115 384.0 0.0 7.1e-115 383.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAP85315.1 - 3.5e-26 91.9 0.0 7.8e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 GAP85315.1 - 0.0031 17.8 1.7 0.0064 16.7 1.7 1.5 1 0 0 1 1 1 1 Herpesvirus UL14-like protein Ntox3 PF15536.6 GAP85321.1 - 0.0082 16.2 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial toxin 3 KSHV_K1 PF11049.8 GAP85321.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus Nbas_N PF15492.6 GAP85322.1 - 0.047 13.0 0.1 5.7 6.2 0.0 2.9 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 GAP85322.1 - 0.13 13.2 0.8 33 5.6 0.1 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat RCC1_2 PF13540.6 GAP85322.1 - 0.96 9.3 0.0 0.96 9.3 0.0 4.0 6 0 0 6 6 6 0 Regulator of chromosome condensation (RCC1) repeat GFA PF04828.14 GAP85324.1 - 7.4e-16 58.3 3.5 1.1e-15 57.7 3.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme LMBR1 PF04791.16 GAP85325.1 - 6.4e-16 58.4 22.6 7.4e-14 51.5 19.5 2.6 2 1 0 2 2 2 1 LMBR1-like membrane protein Fungal_trans PF04082.18 GAP85326.1 - 1e-24 87.0 1.5 1e-24 87.0 1.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ldh_2 PF02615.14 GAP85327.1 - 5.4e-126 420.2 0.9 6.1e-126 420.1 0.9 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase ILVD_EDD PF00920.21 GAP85328.1 - 1.1e-156 522.5 3.0 1.3e-156 522.2 3.0 1.0 1 0 0 1 1 1 1 Dehydratase family Dabb PF07876.12 GAP85328.1 - 1.6e-10 41.4 0.2 2.9e-10 40.6 0.2 1.4 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Metallophos PF00149.28 GAP85329.1 - 1.6e-35 123.4 0.0 2.6e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAP85329.1 - 1.8e-15 57.1 0.1 3.1e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain SUR7 PF06687.12 GAP85330.1 - 1.2e-34 119.8 9.4 1.9e-34 119.2 9.4 1.3 1 0 0 1 1 1 1 SUR7/PalI family WD40 PF00400.32 GAP85330.1 - 7e-16 58.3 6.1 7e-05 23.5 0.3 9.8 11 0 0 11 11 11 3 WD domain, G-beta repeat HicB_lk_antitox PF15919.5 GAP85330.1 - 0.14 12.2 0.1 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system SRP-alpha_N PF04086.13 GAP85331.1 - 0.031 14.2 4.9 0.035 14.0 4.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SR-25 PF10500.9 GAP85331.1 - 0.035 13.7 8.6 0.044 13.4 8.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FancD2 PF14631.6 GAP85331.1 - 0.084 10.3 0.8 0.097 10.1 0.8 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF755 PF05501.11 GAP85331.1 - 0.11 12.8 8.8 0.16 12.3 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Dehydrin PF00257.19 GAP85331.1 - 0.12 12.9 7.7 0.17 12.4 7.7 1.2 1 0 0 1 1 1 0 Dehydrin RAP1 PF07218.11 GAP85331.1 - 6.2 5.0 5.6 6.5 4.9 5.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RRF PF01765.19 GAP85332.1 - 5.1e-15 55.8 0.2 6e-15 55.6 0.2 1.0 1 0 0 1 1 1 1 Ribosome recycling factor Mobilization_B PF17511.2 GAP85332.1 - 0.01 16.2 1.4 0.017 15.5 1.4 1.3 1 0 0 1 1 1 0 Mobilization protein B WXG100 PF06013.12 GAP85332.1 - 0.093 13.0 0.2 0.21 11.8 0.0 1.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Aldedh PF00171.22 GAP85334.1 - 3.4e-167 556.6 0.4 3.8e-167 556.5 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_79C PF16862.5 GAP85335.1 - 3.5e-21 76.0 0.5 1.2e-20 74.3 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain SUR7 PF06687.12 GAP85336.1 - 0.01 15.5 0.3 0.01 15.5 0.3 1.9 1 1 1 2 2 2 0 SUR7/PalI family HATPase_c PF02518.26 GAP85337.1 - 4.1e-23 82.0 0.1 9.3e-23 80.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAP85337.1 - 4.1e-21 75.2 0.1 9.1e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 GAP85337.1 - 2e-10 40.9 0.0 0.00037 20.7 0.0 3.7 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 GAP85337.1 - 3.2e-07 30.3 1.4 9.3e-07 28.8 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 GAP85337.1 - 1.4e-06 28.5 0.0 4.4e-05 23.7 0.0 3.1 2 1 1 3 3 3 1 PAS domain PAS PF00989.25 GAP85337.1 - 9.2e-06 25.6 0.1 0.013 15.5 0.0 3.6 2 1 1 3 3 3 2 PAS fold GAF_2 PF13185.6 GAP85337.1 - 3e-05 24.3 0.0 0.16 12.2 0.0 3.0 2 0 0 2 2 2 2 GAF domain PAS_3 PF08447.12 GAP85337.1 - 0.0065 16.7 0.5 0.019 15.2 0.2 2.0 2 0 0 2 2 2 1 PAS fold GAF_3 PF13492.6 GAP85337.1 - 0.019 15.3 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 GAF domain PAS_8 PF13188.7 GAP85337.1 - 0.028 14.5 0.0 0.4 10.8 0.0 2.7 3 0 0 3 3 3 0 PAS domain CENP-Q PF13094.6 GAP85337.1 - 1.6 8.9 4.0 0.39 10.9 0.4 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fungal_trans PF04082.18 GAP85338.1 - 1e-14 54.2 0.0 2.1e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85338.1 - 5.5e-09 36.0 11.0 9.6e-09 35.2 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 GAP85339.1 - 3.7e-09 36.4 0.0 4.7e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAP85339.1 - 0.0024 17.5 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 GAP85339.1 - 0.0068 15.6 0.0 0.033 13.4 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 GAP85339.1 - 0.034 13.2 0.0 0.35 9.8 0.0 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 GAP85339.1 - 0.12 13.0 0.0 0.42 11.2 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF3437 PF11919.8 GAP85340.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Serglycin PF04360.12 GAP85340.1 - 2.9 7.8 16.7 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Serglycin MARVEL PF01284.23 GAP85341.1 - 2.5e-07 30.8 22.9 1.1e-06 28.7 21.7 2.1 1 1 1 2 2 2 1 Membrane-associating domain TssN PF17555.2 GAP85341.1 - 1.6 8.1 7.4 2.5 7.4 7.4 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN Methyltransf_2 PF00891.18 GAP85342.1 - 4.5e-28 98.0 0.0 8.1e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAP85342.1 - 0.00065 20.3 0.1 0.0024 18.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP85342.1 - 0.0035 17.2 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP85342.1 - 0.0071 17.1 0.0 0.018 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 GAP85342.1 - 0.023 14.2 0.0 0.051 13.0 0.0 1.5 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain HTH_AsnC-type PF13404.6 GAP85342.1 - 0.1 12.4 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 GAP85342.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain TolB_N PF04052.13 GAP85342.1 - 0.12 12.6 0.2 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 TolB amino-terminal domain GIT_SHD PF08518.11 GAP85343.1 - 1.1e-23 82.6 7.6 3.1e-12 45.9 1.6 3.2 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT THP2 PF09432.10 GAP85343.1 - 0.086 12.9 5.3 0.1 12.6 3.7 1.9 1 1 0 1 1 1 0 Tho complex subunit THP2 DUF1843 PF08898.10 GAP85343.1 - 0.11 13.1 0.1 0.42 11.1 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) PSII_Pbs27 PF13326.6 GAP85343.1 - 2.3 8.5 10.5 4.8 7.5 6.6 3.0 2 1 0 2 2 2 0 Photosystem II Pbs27 FUSC PF04632.12 GAP85343.1 - 7.9 4.9 20.3 7.1 5.0 16.0 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Ssu72 PF04722.13 GAP85344.1 - 3.2e-85 284.5 0.0 3.6e-85 284.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.28 GAP85345.1 - 2.5e-09 36.6 0.0 4.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAP85345.1 - 2.7e-08 33.5 0.1 5.2e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAP85345.1 - 0.00043 19.9 0.0 0.0008 19.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Glyco_transf_28 PF03033.20 GAP85346.1 - 2.3e-18 66.6 0.5 1e-10 41.8 0.1 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 GAP85346.1 - 6.7e-05 21.9 0.0 0.00013 20.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 GAP85346.1 - 0.00019 21.7 0.0 0.00065 20.0 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain UIM PF02809.20 GAP85346.1 - 0.078 12.9 31.7 0.35 10.9 0.1 7.1 7 0 0 7 7 7 0 Ubiquitin interaction motif CCD PF07860.11 GAP85346.1 - 0.084 12.9 1.6 0.2 11.7 0.8 2.0 2 0 0 2 2 2 0 WisP family C-Terminal Region Glyco_tran_28_C PF04101.16 GAP85346.1 - 0.091 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain HSP70 PF00012.20 GAP85347.1 - 1.9e-223 743.1 6.6 2.1e-223 742.9 6.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAP85347.1 - 7.2e-15 54.6 0.1 1.5e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GAP85347.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GAP85347.1 - 0.0023 18.3 0.3 3.4 8.1 0.0 3.6 3 1 0 3 3 3 1 Cell division protein FtsA BcrAD_BadFG PF01869.20 GAP85347.1 - 0.03 13.8 0.1 7.4 6.0 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Bromodomain PF00439.25 GAP85348.1 - 2.2e-31 107.8 0.3 2.2e-15 56.5 0.1 2.4 2 0 0 2 2 2 2 Bromodomain SDA1 PF05285.12 GAP85348.1 - 0.0016 17.9 15.9 0.0024 17.4 15.9 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 GAP85348.1 - 0.039 12.2 18.2 0.031 12.5 15.3 1.9 2 0 0 2 2 2 0 Nop14-like family eIF3_subunit PF08597.10 GAP85348.1 - 0.082 12.8 13.2 0.17 11.8 13.2 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit EF1G PF00647.19 GAP85348.1 - 0.12 12.5 0.4 0.73 9.9 0.1 2.1 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain BUD22 PF09073.10 GAP85348.1 - 0.92 8.8 20.4 1.7 7.9 20.4 1.4 1 0 0 1 1 1 0 BUD22 CKS PF01111.19 GAP85349.1 - 7e-35 119.1 1.5 9.2e-35 118.7 1.5 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ERO1 PF04137.15 GAP85350.1 - 4.8e-137 456.9 0.1 7.4e-137 456.3 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HVSL PF09749.9 GAP85351.1 - 2e-68 230.4 0.0 1.9e-67 227.2 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.11 GAP85352.1 - 4.2e-09 37.3 0.1 5.2e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Pal1 cell morphology protein CPSF_A PF03178.15 GAP85354.1 - 4e-82 276.1 0.0 8.7e-82 275.0 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 GAP85354.1 - 4.7e-15 55.2 0.0 8.5e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PBP1_TM PF14812.6 GAP85354.1 - 0.031 14.6 0.3 0.082 13.3 0.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PapC_C PF13953.6 GAP85354.1 - 0.11 12.4 0.2 2.8 7.8 0.0 2.8 2 0 0 2 2 2 0 PapC C-terminal domain RNA_pol_Rpb1_1 PF04997.12 GAP85358.1 - 2e-104 349.3 0.1 3.2e-104 348.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 GAP85358.1 - 4.8e-100 334.4 0.0 9.3e-100 333.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAP85358.1 - 4.4e-77 258.0 0.0 8.5e-77 257.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 GAP85358.1 - 7e-55 185.8 0.9 1.1e-54 185.1 0.9 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 GAP85358.1 - 4.9e-44 150.0 0.0 1.3e-43 148.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 GAP85358.1 - 3.9e-39 133.7 2.9 1.7e-38 131.7 2.7 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 GAP85358.1 - 6.2e-36 122.6 0.0 1.5e-35 121.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 GAP85358.1 - 0.0062 16.8 12.1 0.0062 16.8 12.1 14.0 9 2 1 14 14 14 9 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.32 GAP85359.1 - 1.6e-14 54.0 5.4 3e-05 24.7 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP85359.1 - 3.1e-09 37.0 1.3 0.0014 18.9 0.0 5.1 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAP85359.1 - 1.4e-05 25.1 0.1 0.047 13.6 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 GAP85359.1 - 0.0004 20.0 0.6 0.01 15.5 0.0 2.7 2 1 0 2 2 2 1 PQQ-like domain Thg1 PF04446.12 GAP85360.1 - 1.9e-52 176.6 0.0 2.8e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 GAP85360.1 - 7.9e-51 171.3 0.9 1.1e-50 170.9 0.9 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain G-patch PF01585.23 GAP85361.1 - 0.008 16.0 0.1 0.031 14.2 0.1 2.0 1 1 0 1 1 1 1 G-patch domain MRP-S32 PF10210.9 GAP85361.1 - 6.1 7.5 12.9 13 6.5 12.9 1.6 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 VIR_N PF15912.5 GAP85361.1 - 8 6.0 6.6 11 5.6 6.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal ANAPC_CDC26 PF10471.9 GAP85362.1 - 8.1e-10 39.4 21.8 8.1e-10 39.4 21.8 5.3 3 3 0 3 3 3 1 Anaphase-promoting complex APC subunit CDC26 CENP-B_dimeris PF09026.10 GAP85362.1 - 0.00013 22.3 8.3 0.00013 22.3 8.3 3.5 3 0 0 3 3 3 1 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.8 GAP85362.1 - 0.02 15.2 28.7 0.021 15.1 0.2 3.1 4 0 0 4 4 4 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 GAP85362.1 - 0.042 13.2 20.8 0.25 10.6 13.1 2.4 2 0 0 2 2 2 0 NOA36 protein Cwf_Cwc_15 PF04889.12 GAP85362.1 - 0.23 11.2 36.3 0.016 15.0 18.7 2.7 3 1 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 GAP85362.1 - 0.93 7.6 24.4 0.036 12.3 14.5 2.2 2 0 0 2 2 2 0 Nop14-like family CEP19 PF14933.6 GAP85362.1 - 6 7.1 12.2 0.44 10.8 5.5 2.3 1 1 1 2 2 2 0 CEP19-like protein Peptidase_M1_N PF17900.1 GAP85363.1 - 3.5e-08 33.9 0.0 0.00013 22.2 0.0 2.9 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain APG6_N PF17675.1 GAP85363.1 - 0.00098 19.7 3.0 0.0034 17.9 3.0 1.9 1 0 0 1 1 1 1 Apg6 coiled-coil region HEAT_2 PF13646.6 GAP85363.1 - 0.0074 16.6 0.4 0.042 14.2 0.0 2.4 3 0 0 3 3 3 1 HEAT repeats Peptidase_M1 PF01433.20 GAP85363.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M1 domain HEAT PF02985.22 GAP85363.1 - 0.089 13.1 0.0 16 6.0 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat SAS4 PF15460.6 GAP85364.1 - 2.3e-31 107.8 0.2 1.2e-30 105.5 0.2 2.3 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DUF2722 PF10846.8 GAP85364.1 - 0.06 12.3 0.1 0.06 12.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Nop14 PF04147.12 GAP85364.1 - 0.093 10.9 18.9 0.15 10.3 18.9 1.3 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 GAP85364.1 - 0.87 9.1 14.0 1.9 8.0 14.0 1.5 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 GAP85364.1 - 0.93 9.7 23.4 0.037 14.3 16.4 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 GAP85364.1 - 1.1 8.5 23.0 0.15 11.4 18.2 1.9 2 0 0 2 2 2 0 BUD22 IQ PF00612.27 GAP85365.1 - 2.6e-05 23.6 1.3 9.2e-05 21.9 1.3 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cellulase PF00150.18 GAP85366.1 - 2.1e-19 70.0 0.0 3e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 GAP85366.1 - 4.2e-14 52.2 10.5 2.1e-13 49.9 10.5 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF4038 PF13204.6 GAP85366.1 - 0.00031 20.5 0.1 0.00045 20.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 GAP85366.1 - 0.005 16.0 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 GAP85366.1 - 0.0057 16.0 0.0 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase MGC-24 PF05283.11 GAP85366.1 - 0.019 15.4 5.4 0.053 14.0 5.4 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TFX_C PF14601.6 GAP85366.1 - 0.074 13.0 0.0 0.97 9.4 0.0 2.1 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term Alpha-amylase PF00128.24 GAP85366.1 - 0.12 11.9 0.0 11 5.4 0.0 2.6 3 0 0 3 3 3 0 Alpha amylase, catalytic domain Sporozoite_P67 PF05642.11 GAP85366.1 - 7.7 4.5 6.3 11 3.9 6.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC_membrane_2 PF06472.15 GAP85367.1 - 2.7e-92 309.0 2.2 3.3e-91 305.5 0.0 2.6 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 GAP85367.1 - 1.1e-16 61.6 0.0 2.8e-16 60.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 GAP85367.1 - 0.015 15.7 0.8 0.035 14.5 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain End3 PF12761.7 GAP85367.1 - 0.038 14.2 1.2 0.15 12.2 1.8 1.6 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 THOC7 PF05615.13 GAP85367.1 - 0.039 14.2 1.5 0.087 13.1 1.5 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 AAA PF00004.29 GAP85367.1 - 0.04 14.3 0.2 0.37 11.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GAP85367.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 GAP85367.1 - 0.081 12.7 0.1 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAP85367.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 GAP85367.1 - 0.26 11.8 8.9 5.9 7.3 8.9 2.4 1 1 0 1 1 1 0 AAA domain NIF PF03031.18 GAP85368.1 - 2.8e-54 183.1 0.2 3.8e-54 182.7 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1713 PF08213.11 GAP85369.1 - 6.1e-10 38.8 20.7 6.1e-10 38.8 20.7 2.0 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Arginase PF00491.21 GAP85370.1 - 7.3e-74 248.8 0.1 9.4e-74 248.4 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 GAP85370.1 - 0.15 12.3 0.4 0.22 11.7 0.4 1.2 1 0 0 1 1 1 0 UPF0489 domain Fungal_trans PF04082.18 GAP85371.1 - 1.9e-11 43.5 0.1 2.9e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85371.1 - 2.7e-05 24.2 7.6 2.7e-05 24.2 7.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAP85372.1 - 4.7e-26 91.5 40.6 9e-22 77.5 20.6 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP85372.1 - 5.2e-05 22.3 0.5 5.2e-05 22.3 0.5 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter SET PF00856.28 GAP85375.1 - 1.5e-05 25.4 0.1 6.2e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 SET domain Peptidase_M16 PF00675.20 GAP85376.1 - 6.1e-55 185.3 0.4 2.1e-54 183.6 0.1 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAP85376.1 - 7.5e-36 123.9 0.0 3.5e-35 121.7 0.0 2.1 3 0 0 3 3 3 1 Peptidase M16 inactive domain Esterase PF00756.20 GAP85376.1 - 0.06 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Raffinose_syn PF05691.12 GAP85377.1 - 9.6e-54 182.4 2.1 4.2e-49 167.0 1.8 3.2 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Hydrolase_4 PF12146.8 GAP85378.1 - 9e-05 21.8 0.0 0.036 13.3 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP85378.1 - 0.0001 22.0 0.0 0.0036 17.0 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP85378.1 - 0.00066 20.4 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAP85378.1 - 0.045 13.2 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4121 PF13497.6 GAP85379.1 - 0.094 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) DUF3270 PF11674.8 GAP85380.1 - 0.14 12.4 0.5 0.46 10.7 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) LRR_4 PF12799.7 GAP85382.1 - 1.2e-41 140.0 55.4 4.3e-09 36.5 1.3 7.7 1 1 11 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAP85382.1 - 1.3e-22 79.3 29.6 1.5e-07 31.1 4.3 6.1 1 1 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 GAP85382.1 - 1.5e-15 57.1 14.5 7e-07 28.9 4.2 4.2 1 1 3 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 GAP85382.1 - 0.00053 19.8 22.2 0.79 9.9 0.1 8.3 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.33 GAP85382.1 - 0.044 14.3 24.2 30 5.7 0.1 9.2 10 1 0 10 10 10 0 Leucine Rich Repeat Pox_M2 PF04887.12 GAP85382.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Poxvirus M2 protein Aldo_ket_red PF00248.21 GAP85383.1 - 8.9e-30 103.9 0.0 1.8e-29 102.9 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 GAP85384.1 - 0.0036 16.6 0.1 0.0043 16.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 GAP85385.1 - 6.6e-09 35.5 0.0 0.00026 20.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP85385.1 - 2.7e-07 30.1 0.0 3.9e-06 26.3 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Cellulase PF00150.18 GAP85386.1 - 6.6e-16 58.6 1.8 9.7e-16 58.0 1.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3377 PF11857.8 GAP85387.1 - 0.0026 17.7 2.5 0.097 12.6 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3377) Cation_ATPase_C PF00689.21 GAP85387.1 - 0.97 9.1 12.2 2.6 7.7 1.1 2.4 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus PS-DH PF14765.6 GAP85388.1 - 1.7e-59 201.5 0.0 4.1e-59 200.3 0.0 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.10 GAP85388.1 - 1.1e-55 188.4 0.4 2.4e-55 187.2 0.4 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 GAP85388.1 - 1.1e-52 179.5 0.0 1.9e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 GAP85388.1 - 4.1e-45 154.3 0.0 1.6e-44 152.4 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAP85388.1 - 5e-34 116.8 0.0 1.5e-33 115.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAP85388.1 - 2.7e-24 85.8 0.0 5.5e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension MFS_1 PF07690.16 GAP85388.1 - 5.2e-24 84.8 35.5 8.8e-24 84.1 35.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.26 GAP85388.1 - 1.3e-15 57.6 0.0 4.9e-15 55.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP85388.1 - 3e-11 44.5 0.0 6.9e-10 40.1 0.0 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAP85388.1 - 9e-11 41.6 0.2 2.1e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Sugar_tr PF00083.24 GAP85388.1 - 4.7e-10 38.9 11.9 8.6e-10 38.1 11.9 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter ADH_N PF08240.12 GAP85388.1 - 9.5e-08 31.9 0.2 3.1e-07 30.3 0.2 1.8 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 GAP85388.1 - 7.7e-07 29.4 0.1 3.1e-06 27.5 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 GAP85388.1 - 1.9e-06 27.6 0.1 4.1e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 GAP85388.1 - 0.00062 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 GAP85388.1 - 0.00073 19.3 2.0 0.017 14.9 0.2 2.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis 3Beta_HSD PF01073.19 GAP85388.1 - 0.0016 17.5 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.6 GAP85388.1 - 0.002 18.0 0.0 0.0053 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP85388.1 - 0.016 15.9 0.0 0.063 14.0 0.0 2.1 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAP85388.1 - 0.063 13.9 0.0 0.31 11.7 0.0 2.3 1 0 0 1 1 1 0 Methyltransferase domain Thiolase_N PF00108.23 GAP85388.1 - 0.096 12.0 0.2 0.23 10.8 0.2 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 GAP85388.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RRN9 PF10680.9 GAP85389.1 - 8.7e-18 64.4 0.3 8.7e-18 64.4 0.3 2.5 3 0 0 3 3 3 1 RNA polymerase I specific transcription initiation factor Peptidase_M35 PF02102.15 GAP85389.1 - 0.1 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Pescadillo_N PF06732.11 GAP85390.1 - 9.3e-123 409.1 0.0 9.3e-123 409.1 0.0 1.6 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.26 GAP85390.1 - 8.4e-06 26.1 0.0 3e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAP85390.1 - 0.0026 18.2 0.1 0.012 16.0 0.0 2.3 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Nop53 PF07767.11 GAP85390.1 - 1 8.6 34.7 2 7.7 34.7 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PIG-U PF06728.13 GAP85391.1 - 1e-119 400.1 31.4 1.1e-119 399.9 31.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF3687 PF12459.8 GAP85391.1 - 0.35 10.4 5.3 1.1 8.8 4.1 2.4 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein 8TM_micro PF17028.5 GAP85391.1 - 0.84 9.3 10.2 5.1 6.7 10.2 2.3 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain MFS_1 PF07690.16 GAP85392.1 - 5.2e-34 117.7 41.9 8.1e-34 117.1 36.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1230 PF06799.11 GAP85392.1 - 0.05 13.7 2.0 0.066 13.3 0.1 2.1 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 FAD_binding_3 PF01494.19 GAP85393.1 - 1.7e-10 40.7 0.2 0.0022 17.3 0.1 3.0 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 GAP85393.1 - 0.00017 21.7 0.0 0.00038 20.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP85393.1 - 0.002 17.4 0.0 0.39 9.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP85393.1 - 0.004 16.8 0.2 0.018 14.7 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAP85393.1 - 0.022 15.3 0.0 0.4 11.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 GAP85393.1 - 0.19 11.4 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 GAP85393.1 - 0.29 10.4 0.0 0.44 9.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CDT1_C PF16679.5 GAP85394.1 - 0.055 13.9 0.0 0.093 13.2 0.0 1.3 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Tom37 PF10568.9 GAP85395.1 - 2.1e-31 108.8 0.1 3.5e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 GAP85395.1 - 0.00032 20.4 0.1 0.00098 18.9 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP85395.1 - 0.0038 17.2 0.1 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAP85395.1 - 0.0041 17.8 0.0 0.012 16.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain tRNA-synt_1 PF00133.22 GAP85397.1 - 6.9e-154 513.4 0.0 1e-153 512.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GAP85397.1 - 3.2e-20 72.2 0.2 2.8e-12 46.1 0.0 3.9 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAP85397.1 - 2.8e-15 56.6 0.0 5.8e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.14 GAP85397.1 - 0.0028 17.5 5.9 0.0078 16.0 5.9 1.8 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 GAP85397.1 - 0.012 15.0 0.0 0.99 8.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 GAP85397.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Kinesin PF00225.23 GAP85399.1 - 4.1e-108 361.2 0.4 7.6e-108 360.4 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 GAP85399.1 - 4.3e-25 88.4 0.7 5.5e-24 84.8 0.0 3.0 3 0 0 3 3 3 1 Microtubule binding Microtub_bind PF13931.6 GAP85399.1 - 1.3e-07 32.0 3.9 1.3e-07 32.0 3.9 5.4 5 1 0 5 5 5 2 Kinesin-associated microtubule-binding Phasin PF05597.11 GAP85399.1 - 0.21 11.6 24.1 0.51 10.3 1.0 5.8 3 2 2 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TetR_C_23 PF17931.1 GAP85399.1 - 0.45 10.6 4.5 0.25 11.5 0.4 2.8 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain UPF0183 PF03676.14 GAP85400.1 - 1.4e-58 199.0 0.0 2.7e-36 125.7 0.0 3.1 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0183) Epimerase PF01370.21 GAP85401.1 - 7.3e-09 35.4 2.5 1.4e-07 31.2 2.5 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP85401.1 - 5.4e-05 22.7 0.9 6.6e-05 22.5 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAP85401.1 - 0.0001 21.6 0.0 0.0011 18.3 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein NmrA PF05368.13 GAP85401.1 - 0.0014 18.3 0.7 0.0024 17.5 0.7 1.6 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 GAP85401.1 - 0.047 12.7 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 GAP85401.1 - 0.69 9.3 4.5 1.2 8.5 0.9 2.3 2 0 0 2 2 2 0 short chain dehydrogenase FMO-like PF00743.19 GAP85402.1 - 5.9e-56 190.0 0.0 1.5e-53 182.0 0.0 3.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAP85402.1 - 2.9e-17 62.8 0.0 6.9e-14 51.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP85402.1 - 7.8e-15 54.9 0.0 8e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP85402.1 - 1.8e-08 34.8 0.0 0.0016 18.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP85402.1 - 4.2e-08 33.3 0.1 1.2e-07 31.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 GAP85402.1 - 7.5e-07 28.6 0.0 0.00015 21.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAP85402.1 - 7.4e-06 26.0 0.3 0.12 12.3 0.0 3.9 4 0 0 4 4 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAP85402.1 - 0.00084 18.7 0.1 0.002 17.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 GAP85402.1 - 0.001 19.5 0.0 1.8 9.0 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.14 GAP85402.1 - 0.0022 16.8 0.1 0.0039 16.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 GAP85402.1 - 0.0022 17.3 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 GAP85402.1 - 0.0048 16.5 0.4 0.068 12.7 0.2 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP85402.1 - 0.0066 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain IlvN PF07991.12 GAP85402.1 - 0.015 14.9 0.0 0.95 9.0 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_oxidored PF12831.7 GAP85402.1 - 0.021 14.2 1.3 0.056 12.8 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAP85402.1 - 0.023 14.0 0.1 0.065 12.5 0.0 1.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 GAP85402.1 - 0.098 12.7 0.0 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 GAP85402.1 - 0.23 10.7 0.1 0.47 9.7 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cep57_MT_bd PF06657.13 GAP85403.1 - 2.4e-18 66.4 0.5 2.4e-18 66.4 0.5 4.8 5 0 0 5 5 5 2 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 GAP85403.1 - 3.3e-06 27.1 13.3 3.3e-06 27.1 13.3 5.0 3 1 0 4 4 4 2 Centrosome localisation domain of PPC89 WXG100 PF06013.12 GAP85403.1 - 0.0097 16.1 4.0 0.0097 16.1 4.0 3.9 4 0 0 4 4 4 1 Proteins of 100 residues with WXG TMF_DNA_bd PF12329.8 GAP85403.1 - 4.1 7.5 35.8 0.64 10.1 0.9 5.0 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding RRM_1 PF00076.22 GAP85404.1 - 1.4e-12 47.3 0.0 2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.7 GAP85404.1 - 0.0034 18.0 22.3 0.0034 18.0 22.3 1.6 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RRM_3 PF08777.11 GAP85404.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 RNA binding motif Transformer PF06495.11 GAP85404.1 - 0.55 10.3 11.0 0.79 9.8 11.0 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein DUF3915 PF13054.6 GAP85404.1 - 2 8.4 9.4 3.5 7.6 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 GAP85404.1 - 2.8 6.1 12.5 3.5 5.8 12.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family UQ_con PF00179.26 GAP85405.1 - 2e-25 89.1 0.0 3.3e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 GAP85405.1 - 0.0095 15.6 0.1 0.039 13.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 GAP85405.1 - 0.038 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 GAP85405.1 - 0.039 13.6 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 GAP85405.1 - 0.096 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain DHHC PF01529.20 GAP85406.1 - 1.3e-30 106.2 0.0 2.1e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase CDC45 PF02724.14 GAP85406.1 - 0.00043 18.7 0.0 0.00057 18.3 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein Oxidored_q2 PF00420.24 GAP85406.1 - 0.042 13.5 0.6 0.068 12.8 0.6 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Nop14 PF04147.12 GAP85406.1 - 0.32 9.2 6.3 0.41 8.8 6.3 1.0 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L40e PF01020.17 GAP85406.1 - 0.36 10.8 9.5 0.7 9.8 9.5 1.4 1 0 0 1 1 1 0 Ribosomal L40e family DZR PF12773.7 GAP85406.1 - 0.88 9.6 9.6 1.6 8.8 9.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon Myosin_head PF00063.21 GAP85408.1 - 4.3e-237 788.6 5.4 5.1e-237 788.4 5.4 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 GAP85408.1 - 4.2e-48 163.5 0.0 7.5e-48 162.7 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 GAP85408.1 - 2.5e-13 49.4 0.1 5.1e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAP85408.1 - 8.2e-10 38.4 0.0 1.9e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAP85408.1 - 4e-08 32.8 0.0 1.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.27 GAP85408.1 - 0.006 16.3 11.4 0.19 11.6 3.3 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 GAP85408.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 GAP85408.1 - 0.053 13.0 0.6 4.7 6.7 0.1 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.27 GAP85408.1 - 0.09 13.3 0.7 0.42 11.1 0.0 2.4 3 0 0 3 3 3 0 ABC transporter SH3_3 PF08239.11 GAP85408.1 - 0.091 13.1 0.3 0.24 11.7 0.3 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain AAA_16 PF13191.6 GAP85408.1 - 0.1 13.0 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 GAP85408.1 - 0.16 11.6 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 GAP85408.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 GAP85408.1 - 0.18 11.1 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF4913 PF16259.5 GAP85408.1 - 0.24 11.5 1.0 0.63 10.1 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) NAD_binding_6 PF08030.12 GAP85410.1 - 2.5e-22 79.7 0.0 4.2e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAP85410.1 - 3.3e-22 78.6 0.0 7.2e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 GAP85410.1 - 1.6e-21 76.7 9.5 1.6e-21 76.7 9.5 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component LrgA PF03788.14 GAP85410.1 - 0.035 14.0 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 LrgA family FAD_binding_6 PF00970.24 GAP85410.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAP85410.1 - 0.12 13.0 0.0 3.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4780 PF16012.5 GAP85410.1 - 0.46 9.9 1.4 0.78 9.2 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4780) Solute_trans_a PF03619.16 GAP85411.1 - 1.1e-45 156.2 7.5 1.4e-45 155.9 7.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PGG PF13962.6 GAP85411.1 - 0.061 13.2 3.8 2 8.3 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function CENP-B_dimeris PF09026.10 GAP85411.1 - 0.93 9.9 6.0 2 8.9 6.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 GAP85411.1 - 2.2 7.5 5.4 3.7 6.8 5.4 1.3 1 0 0 1 1 1 0 NOA36 protein DUF829 PF05705.14 GAP85412.1 - 2.5e-51 174.9 0.0 3e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) F-box PF00646.33 GAP85413.1 - 0.022 14.6 0.1 0.19 11.6 0.0 2.5 2 0 0 2 2 2 0 F-box domain fn3 PF00041.21 GAP85414.1 - 7e-07 29.5 0.0 1.7e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Peptidase_S49 PF01343.18 GAP85414.1 - 0.53 10.2 4.2 1.2 9.1 4.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 GST_N_2 PF13409.6 GAP85415.1 - 1e-06 29.0 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAP85415.1 - 1.2e-06 28.8 0.0 2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP85415.1 - 0.00081 19.4 0.9 0.002 18.1 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Cyt-b5 PF00173.28 GAP85416.1 - 3e-17 62.5 0.0 4.4e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NIBRIN_BRCT_II PF16508.5 GAP85417.1 - 1.2e-37 128.9 0.0 3.8e-37 127.2 0.0 1.9 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 GAP85417.1 - 2.5e-09 37.3 0.0 5.5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 GAP85417.1 - 0.00037 20.3 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 GAP85417.1 - 0.0019 18.5 0.1 0.0071 16.6 0.1 2.0 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain HET PF06985.11 GAP85418.1 - 2.7e-24 86.2 0.0 5.4e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) KcnmB2_inactiv PF09303.10 GAP85418.1 - 2.2 8.1 4.3 2.9 7.8 0.7 3.0 3 0 0 3 3 3 0 KCNMB2, ball and chain domain SelP_N PF04592.14 GAP85419.1 - 6.4 6.1 11.4 7.9 5.8 11.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Acetyltransf_1 PF00583.25 GAP85420.1 - 4.5e-12 46.2 0.0 6.3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP85420.1 - 5.7e-07 29.9 0.0 8.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAP85420.1 - 3.8e-06 26.9 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP85420.1 - 6.8e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GAP85420.1 - 0.0062 17.2 0.0 0.0086 16.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAP85420.1 - 0.018 15.2 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain rve_3 PF13683.6 GAP85420.1 - 0.091 12.6 0.1 6 6.7 0.0 2.3 1 1 0 2 2 2 0 Integrase core domain PALP PF00291.25 GAP85421.1 - 3.2e-78 263.1 0.3 4e-78 262.8 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 GAP85421.1 - 7.3e-43 144.3 0.0 3.2e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Glyco_hydro_47 PF01532.20 GAP85422.1 - 5.7e-172 572.7 0.0 6.7e-172 572.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 GAP85422.1 - 0.067 12.4 0.1 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) TFIIA PF03153.13 GAP85423.1 - 0.0011 19.0 12.9 0.0014 18.7 12.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1689 PF07954.11 GAP85423.1 - 0.0025 18.2 2.4 1 9.7 2.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1689) Roughex PF06020.11 GAP85423.1 - 0.028 13.6 2.9 0.039 13.1 2.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein TMEM51 PF15345.6 GAP85423.1 - 0.041 13.7 2.8 0.062 13.1 2.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2722 PF10846.8 GAP85423.1 - 0.13 11.2 15.6 0.17 10.8 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) EphA2_TM PF14575.6 GAP85423.1 - 0.2 12.5 1.5 0.88 10.5 1.5 2.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4770 PF15994.5 GAP85423.1 - 0.27 11.4 6.6 0.42 10.8 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Med3 PF11593.8 GAP85423.1 - 0.4 9.8 10.8 0.65 9.1 10.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 GAP85423.1 - 0.52 9.9 25.8 0.83 9.2 25.8 1.2 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 GAP85423.1 - 0.72 8.8 9.8 0.94 8.4 9.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Activator_LAG-3 PF11498.8 GAP85423.1 - 0.76 8.7 28.8 1 8.2 28.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Presenilin PF01080.17 GAP85423.1 - 0.77 8.5 10.9 1.3 7.7 5.5 2.6 2 0 0 2 2 2 0 Presenilin DUF3682 PF12446.8 GAP85423.1 - 2.1 8.8 12.4 3.4 8.1 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) MMR1 PF08505.10 GAP85423.1 - 2.3 8.5 10.3 3.3 7.9 10.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Dicty_REP PF05086.12 GAP85423.1 - 2.4 6.1 6.1 3.1 5.7 6.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF5349 PF17298.2 GAP85423.1 - 3 7.5 12.1 4.1 7.1 12.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Pex14_N PF04695.13 GAP85423.1 - 8.9 7.0 17.2 0.5 11.0 11.8 1.6 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Histidinol_dh PF00815.20 GAP85424.1 - 1e-161 538.6 4.2 1.7e-161 537.8 4.2 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 GAP85424.1 - 1.4e-24 85.7 0.1 2.7e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 GAP85424.1 - 2.9e-13 50.1 1.0 5.4e-13 49.2 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.15 GAP85425.1 - 1.1e-31 109.4 0.0 7.9e-31 106.7 0.0 1.9 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit SOG2 PF10428.9 GAP85425.1 - 9.4 5.3 7.0 11 5.1 7.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein LNS2 PF08235.13 GAP85426.1 - 7e-92 307.0 0.0 9.4e-92 306.6 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 GAP85426.1 - 2.2e-41 139.9 0.0 5.1e-41 138.8 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 GAP85426.1 - 0.0014 18.2 0.2 0.38 10.3 0.0 2.5 3 0 0 3 3 3 2 HAD superfamily, subfamily IIIB (Acid phosphatase) zf-C2H2_4 PF13894.6 GAP85428.1 - 2e-07 31.2 2.9 0.0056 17.4 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAP85428.1 - 1.9e-06 28.0 3.2 0.0081 16.6 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ima1_N PF09779.9 GAP85428.1 - 0.0074 17.1 1.7 0.019 15.8 0.2 2.0 2 0 0 2 2 2 1 Ima1 N-terminal domain zf-C2H2_6 PF13912.6 GAP85428.1 - 0.021 14.8 1.6 0.28 11.3 0.5 2.4 1 1 1 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 GAP85428.1 - 0.21 11.9 1.1 3.5 8.0 0.7 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.25 GAP85434.1 - 4.6e-70 236.0 0.0 8e-70 235.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP85434.1 - 1.4e-33 116.3 0.0 2.2e-32 112.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAP85434.1 - 2e-05 23.7 0.0 2.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAP85434.1 - 0.0013 18.1 1.0 1 8.6 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 GAP85434.1 - 0.015 14.1 1.4 0.023 13.5 0.0 2.1 2 1 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 GAP85434.1 - 0.037 13.4 0.2 0.072 12.4 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP85434.1 - 0.053 13.4 1.0 0.18 11.7 0.1 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 GAP85434.1 - 0.054 13.1 1.9 0.15 11.7 1.9 1.7 1 1 0 1 1 1 0 RIO1 family Zn_clus PF00172.18 GAP85437.1 - 1.3e-07 31.6 4.7 1.3e-07 31.6 4.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAP85437.1 - 0.0051 15.7 0.1 0.0064 15.3 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3459 PF11941.8 GAP85437.1 - 0.068 13.5 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) RTA1 PF04479.13 GAP85438.1 - 1.1e-51 175.4 2.9 1.8e-51 174.7 2.9 1.3 1 0 0 1 1 1 1 RTA1 like protein Isochorismatase PF00857.20 GAP85438.1 - 1.9e-29 103.1 0.0 4.6e-29 101.8 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family SNF2_N PF00176.23 GAP85440.1 - 5.9e-61 206.1 0.5 1.1e-60 205.2 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP85440.1 - 2.3e-14 53.7 0.0 9e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP85440.1 - 1.1e-10 41.8 0.0 2.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAP85440.1 - 7.9e-08 32.3 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 GAP85440.1 - 4.4e-07 29.6 1.3 1.3e-06 28.1 1.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP85440.1 - 2.1e-05 24.4 2.7 5.8e-05 23.0 2.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAP85440.1 - 2.7e-05 23.9 4.5 7.5e-05 22.5 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP85440.1 - 5.2e-05 23.1 2.9 0.00021 21.1 2.9 2.2 1 0 0 1 1 1 1 zinc-RING finger domain AAA_34 PF13872.6 GAP85440.1 - 0.00011 21.2 0.0 0.00019 20.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4_3 PF13920.6 GAP85440.1 - 0.00023 21.0 4.9 0.00023 21.0 4.9 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP85440.1 - 0.00048 20.4 2.0 0.00048 20.4 2.0 2.4 2 0 0 2 2 1 1 Ring finger domain zf-MYND PF01753.18 GAP85440.1 - 0.00069 19.6 5.1 0.00069 19.6 5.1 2.0 2 0 0 2 2 2 1 MYND finger zf-Nse PF11789.8 GAP85440.1 - 0.0025 17.6 2.8 0.0032 17.3 1.5 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 GAP85440.1 - 0.0038 17.3 4.8 0.011 15.9 4.8 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAP85440.1 - 0.047 13.6 6.5 0.31 10.9 6.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 U71 PF17474.2 GAP85440.1 - 0.24 11.4 1.4 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 Tegument protein UL11 homolog Amidohydro_1 PF01979.20 GAP85441.1 - 2.9e-22 79.5 0.1 1e-18 67.8 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 GAP85441.1 - 3.8e-17 62.9 9.1 9.7e-13 48.4 2.8 2.3 1 1 0 2 2 2 2 Amidohydrolase family Fungal_trans_2 PF11951.8 GAP85442.1 - 1.1e-06 27.8 0.4 3.3e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain CUE PF02845.16 GAP85444.1 - 0.015 15.0 0.2 0.073 12.8 0.0 2.1 2 0 0 2 2 2 0 CUE domain Memo PF01875.17 GAP85445.1 - 4.3e-74 249.1 0.0 4.9e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Syntaxin PF00804.25 GAP85446.1 - 1.3e-19 70.7 20.7 4.4e-19 69.0 20.7 1.8 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 GAP85446.1 - 4.4e-11 42.6 0.9 4.4e-11 42.6 0.9 3.2 4 0 0 4 4 4 1 SNARE domain Moulting_cycle PF04870.16 GAP85446.1 - 0.018 14.4 6.7 0.028 13.7 6.7 1.2 1 0 0 1 1 1 0 Moulting cycle DUF1664 PF07889.12 GAP85446.1 - 0.085 12.9 14.3 0.097 12.7 1.7 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.11 GAP85446.1 - 0.42 10.1 7.4 0.5 9.8 1.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein BLOC1_2 PF10046.9 GAP85446.1 - 0.74 10.2 10.1 3.7 7.9 1.9 3.4 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TssO PF17561.2 GAP85446.1 - 0.95 9.6 7.9 0.77 9.9 1.3 2.7 2 1 0 3 3 3 0 Type VI secretion system, TssO Baculo_p24 PF05073.12 GAP85446.1 - 1 9.1 6.6 3 7.6 0.6 2.3 2 0 0 2 2 2 0 Baculovirus P24 capsid protein DUF4094 PF13334.6 GAP85446.1 - 2.5 8.6 6.0 37 4.8 1.5 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) PBECR5 PF18814.1 GAP85446.1 - 2.6 7.9 13.2 28 4.6 13.2 2.0 1 1 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 Spore_III_AB PF09548.10 GAP85446.1 - 7.2 6.7 11.1 61 3.7 0.1 3.0 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) V-SNARE PF05008.15 GAP85446.1 - 9.2 6.7 15.7 0.35 11.3 3.5 3.7 2 2 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus zf-ANAPC11 PF12861.7 GAP85448.1 - 2e-45 152.8 12.0 2.4e-45 152.5 12.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 GAP85448.1 - 1.7e-21 76.2 12.5 2.5e-21 75.7 12.5 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAP85448.1 - 3.6e-08 33.6 15.6 7.3e-07 29.4 15.6 2.4 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAP85448.1 - 9.6e-06 25.5 7.2 0.00016 21.6 4.7 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAP85448.1 - 0.00031 20.6 14.4 0.0012 18.7 14.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP85448.1 - 0.00084 19.1 7.9 0.00084 19.1 7.9 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 GAP85448.1 - 0.0027 17.9 16.4 0.051 13.7 16.4 3.0 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAP85448.1 - 0.0034 17.0 11.9 0.029 14.0 11.9 2.1 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 GAP85448.1 - 0.0045 16.7 13.4 0.1 12.4 10.7 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 GAP85448.1 - 0.008 16.0 13.8 0.008 16.0 13.8 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAP85448.1 - 0.0086 16.2 11.3 0.012 15.8 9.1 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 GAP85448.1 - 0.012 15.4 5.0 0.022 14.6 5.0 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit YacG PF03884.14 GAP85448.1 - 0.093 12.5 6.3 0.17 11.7 0.2 2.7 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-HIT PF04438.16 GAP85448.1 - 0.1 12.5 1.0 0.1 12.5 1.0 2.3 2 0 0 2 2 2 0 HIT zinc finger Rad50_zn_hook PF04423.14 GAP85448.1 - 0.12 12.2 4.3 0.23 11.3 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_5 PF14634.6 GAP85448.1 - 0.31 11.0 18.0 11 6.1 18.4 2.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 GAP85448.1 - 0.34 10.7 12.8 0.65 9.8 9.2 2.8 2 1 0 2 2 2 0 RING-like zinc finger UBZ_FAAP20 PF15750.5 GAP85448.1 - 0.65 10.0 6.3 2.1 8.4 0.3 2.8 2 1 1 3 3 3 0 Ubiquitin-binding zinc-finger RINGv PF12906.7 GAP85448.1 - 1.1 9.5 13.4 2 8.6 12.3 2.1 1 1 1 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 GAP85448.1 - 3.2 8.1 13.5 6.4 7.2 11.5 2.2 1 1 1 2 2 2 0 RING-like domain Opy2 PF09463.10 GAP85448.1 - 4.2 7.8 11.1 7.8 6.9 6.3 2.4 2 1 0 2 2 2 0 Opy2 protein DZR PF12773.7 GAP85448.1 - 5.9 7.0 13.1 5.4 7.1 5.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon Rhodanese PF00581.20 GAP85449.1 - 6.8e-20 71.6 0.0 2.1e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain PGM_PMM_II PF02879.16 GAP85449.1 - 0.051 14.2 0.0 2.2 8.9 0.0 2.7 3 0 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II WSC PF01822.19 GAP85450.1 - 9.1e-16 57.8 8.2 9.1e-16 57.8 8.2 2.6 2 0 0 2 2 2 1 WSC domain Ribosomal_S5 PF00333.20 GAP85451.1 - 2.3e-27 94.8 1.0 5.1e-27 93.7 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 GAP85451.1 - 5.5e-23 80.2 0.0 9e-23 79.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 GAP85451.1 - 4.1 8.0 14.6 9.9 6.8 14.6 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Cyclin_N PF00134.23 GAP85452.1 - 6.6e-38 129.3 0.7 1.3e-37 128.3 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAP85452.1 - 1.2e-12 47.9 0.2 7.1e-12 45.5 0.2 2.2 1 1 0 1 1 1 1 Cyclin, C-terminal domain Phosducin PF02114.16 GAP85453.1 - 0.038 12.9 2.6 0.071 12.0 2.6 1.3 1 0 0 1 1 1 0 Phosducin ADH_N PF08240.12 GAP85455.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Glyco_hydro_76 PF03663.14 GAP85456.1 - 2.8e-68 231.1 20.9 3.2e-68 230.9 20.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.14 GAP85457.1 - 4.6e-22 79.0 0.0 5.5e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RasGAP PF00616.19 GAP85458.1 - 9.9e-50 169.1 0.0 2.4e-49 167.9 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAP85458.1 - 5.3e-46 156.2 2.9 5.3e-46 156.2 2.9 2.5 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 GAP85458.1 - 1.1e-20 71.4 23.4 0.0028 17.3 0.3 12.1 11 0 0 11 11 11 7 IQ calmodulin-binding motif CH PF00307.31 GAP85458.1 - 1.2e-05 25.4 0.0 3.9e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain YlbD_coat PF14071.6 GAP85458.1 - 1.2 9.4 6.6 0.91 9.8 1.2 3.2 2 1 1 3 3 3 0 Putative coat protein RBD-FIP PF09457.10 GAP85458.1 - 4.4 7.3 7.6 53 3.8 0.6 3.7 3 0 0 3 3 3 0 FIP domain IMPDH PF00478.25 GAP85459.1 - 6.1e-126 420.1 4.4 7.3e-126 419.8 4.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 GAP85459.1 - 4.1e-11 43.2 0.0 0.00014 22.3 0.1 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 GAP85459.1 - 3e-09 36.4 1.3 2e-07 30.4 0.6 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.15 GAP85459.1 - 9.9e-08 31.7 4.8 0.01 15.3 0.0 2.5 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 GAP85459.1 - 0.0019 17.7 2.2 24 4.3 0.1 2.2 1 1 0 1 1 1 0 Histidine biosynthesis protein YpsA PF06908.11 GAP85459.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 YspA SLOG family PK PF00224.21 GAP85459.1 - 0.051 12.5 0.0 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Pyruvate kinase, barrel domain ThiG PF05690.14 GAP85459.1 - 0.14 11.4 3.7 0.21 10.8 1.4 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.16 GAP85460.1 - 8.1e-37 127.0 25.5 9.1e-25 87.3 7.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP85460.1 - 3.5e-08 32.7 1.4 3.5e-08 32.7 1.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1082 PF06449.11 GAP85460.1 - 0.12 12.2 0.1 0.38 10.6 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) TFR_dimer PF04253.15 GAP85461.1 - 2.1e-30 105.3 0.0 3.9e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 GAP85461.1 - 1.4e-18 67.3 0.0 2.5e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAP85461.1 - 2.5e-08 33.8 0.0 6.4e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 GAP85461.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Sigma_reg_N PF13800.6 GAP85462.1 - 0.63 10.4 9.2 0.96 9.8 9.2 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Bunya_G2 PF03563.13 GAP85462.1 - 1.2 8.3 9.4 1.6 7.9 9.4 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 DUF2207 PF09972.9 GAP85462.1 - 2.5 6.8 3.9 3 6.5 3.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3139 PF11337.8 GAP85462.1 - 2.6 8.8 8.8 4.9 7.9 8.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) ASFV_J13L PF05568.11 GAP85462.1 - 4.7 6.9 10.3 8.7 6.0 10.3 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Orf78 PF06024.12 GAP85462.1 - 4.9 7.5 8.0 9 6.7 8.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 GAP85462.1 - 6.6 6.6 13.8 11 5.9 13.8 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF3377 PF11857.8 GAP85462.1 - 9.9 6.2 9.5 11 6.0 6.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Gpr1_Fun34_YaaH PF01184.19 GAP85463.1 - 1.8e-88 295.5 21.3 2.1e-88 295.3 21.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Translin PF01997.16 GAP85464.1 - 2.8e-53 181.0 0.0 3.3e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Translin family Tmemb_cc2 PF10267.9 GAP85464.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein NPV_P10 PF05531.12 GAP85464.1 - 0.16 12.4 0.1 1.3 9.5 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mannosyl_trans PF05007.13 GAP85465.1 - 6.2e-74 249.1 0.9 1.1e-73 248.3 0.9 1.4 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 GAP85465.1 - 4.1e-12 45.8 0.0 4.1e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 GAP85465.1 - 8.1e-07 29.0 13.2 8.1e-07 29.0 13.2 3.3 2 1 0 3 3 3 1 Glycosyltransferase family 87 F-box-like PF12937.7 GAP85466.1 - 1.3e-06 28.2 0.1 8.3e-06 25.6 0.0 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 GAP85466.1 - 1 9.3 3.6 3.9 7.5 0.6 3.0 3 0 0 3 3 3 0 F-box domain Peptidase_S8 PF00082.22 GAP85467.1 - 1.2e-29 103.5 13.5 2.1e-29 102.7 13.5 1.3 1 0 0 1 1 1 1 Subtilase family SQS_PSY PF00494.19 GAP85468.1 - 1.2e-34 120.0 0.0 1.8e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase ADH_N PF08240.12 GAP85469.1 - 2.1e-10 40.4 0.1 4e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP85469.1 - 1.6e-07 31.4 0.4 2.8e-07 30.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 GAP85469.1 - 0.0014 18.5 0.1 0.0031 17.4 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Epimerase PF01370.21 GAP85469.1 - 0.0048 16.4 0.1 0.0074 15.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP85469.1 - 0.17 11.2 0.1 0.24 10.8 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ank_2 PF12796.7 GAP85470.1 - 3.8e-17 62.6 0.0 4.8e-14 52.7 0.0 2.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP85470.1 - 6.9e-13 47.5 0.0 0.0063 16.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 GAP85470.1 - 1.1e-11 45.0 0.0 2.6e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 GAP85470.1 - 7.5e-10 38.8 0.0 0.014 15.8 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 GAP85470.1 - 3e-06 27.4 0.0 0.06 13.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) NmrA PF05368.13 GAP85471.1 - 8e-31 107.4 0.0 2.3e-30 105.9 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP85471.1 - 1.1e-08 35.3 0.0 1.4e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP85471.1 - 0.015 14.7 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAP85471.1 - 0.083 13.1 0.1 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Tubulin PF00091.25 GAP85472.1 - 1.1e-54 185.7 0.1 7.5e-34 117.6 0.0 2.7 2 1 1 3 3 3 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAP85472.1 - 1.3e-36 125.5 0.4 2.7e-36 124.5 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAP85472.1 - 7.3e-05 23.1 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 GAP85472.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 GAP85472.1 - 0.01 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Tubulin like zf_CCCH_4 PF18345.1 GAP85473.1 - 2.7e-11 43.1 21.6 5.8e-07 29.4 4.8 3.4 3 0 0 3 3 3 2 Zinc finger domain IBR PF01485.21 GAP85473.1 - 1.8e-10 40.9 37.6 1.4e-06 28.4 6.5 4.0 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-CCCH PF00642.24 GAP85473.1 - 4.1e-09 36.1 9.1 1.6e-05 24.7 2.1 3.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAP85473.1 - 1.1e-08 34.6 10.9 2.2e-06 27.3 2.3 4.0 4 0 0 4 4 3 2 CCCH-type zinc finger zf-RING_UBOX PF13445.6 GAP85473.1 - 5.1e-06 26.4 6.1 5.1e-06 26.4 6.1 4.5 4 0 0 4 4 3 1 RING-type zinc-finger Torus PF16131.5 GAP85473.1 - 1.2e-05 25.9 4.7 0.0013 19.4 0.3 3.2 2 1 1 3 3 2 2 Torus domain zf-C3HC4 PF00097.25 GAP85473.1 - 5.6e-05 22.9 4.5 5.6e-05 22.9 4.5 4.7 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP85473.1 - 0.00017 21.4 5.6 0.00017 21.4 5.6 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAP85473.1 - 0.00038 20.5 5.3 0.00038 20.5 5.3 4.1 4 1 0 4 4 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAP85473.1 - 0.00077 19.3 4.1 0.00077 19.3 4.1 4.5 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP85473.1 - 0.0013 18.7 7.9 0.0013 18.7 7.9 4.0 3 1 0 3 3 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAP85473.1 - 0.0014 18.9 5.8 0.0014 18.9 5.8 4.1 2 1 1 3 3 2 1 Ring finger domain zf-CCCH_3 PF15663.5 GAP85473.1 - 0.0025 18.0 12.1 0.24 11.6 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger containing family Prok-RING_4 PF14447.6 GAP85473.1 - 0.0048 16.7 4.6 0.0048 16.7 4.6 5.1 4 1 1 5 5 3 1 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 GAP85473.1 - 0.0056 17.1 25.6 0.026 15.0 4.1 4.6 4 0 0 4 4 4 2 RNA-binding, Nab2-type zinc finger zf-RING_11 PF17123.5 GAP85473.1 - 1.5 8.6 8.7 9.7 6.0 4.0 3.1 2 0 0 2 2 2 0 RING-like zinc finger CGI-121 PF08617.10 GAP85474.1 - 6.9e-47 159.6 0.0 8.5e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Pro_dh PF01619.18 GAP85475.1 - 7.9e-65 219.3 0.0 9.4e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Tim17 PF02466.19 GAP85476.1 - 0.013 15.8 7.7 0.045 14.1 7.8 1.8 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 GAP85476.1 - 0.6 10.5 9.2 1.2 9.5 0.5 3.2 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 tRNA_synthFbeta PF17759.1 GAP85478.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain BNR_4 PF15892.5 GAP85479.1 - 4.7e-57 193.4 0.0 6.6e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-containing family member Sugar_tr PF00083.24 GAP85480.1 - 1.3e-125 419.8 17.4 1.5e-125 419.6 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP85480.1 - 4.1e-23 81.9 27.0 1.6e-15 56.9 4.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sulfotransfer_4 PF17784.1 GAP85481.1 - 1e-52 179.1 0.2 1.2e-52 178.9 0.2 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAP85481.1 - 0.00038 20.9 1.3 0.0036 17.7 0.1 2.2 1 1 1 2 2 2 1 Sulfotransferase family Ribosomal_L35Ae PF01247.18 GAP85483.1 - 6.2e-37 125.7 0.0 7e-37 125.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 GAP85483.1 - 0.00051 20.2 0.1 0.41 10.9 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 GAP85483.1 - 0.076 12.8 0.3 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) PMSR PF01625.21 GAP85484.1 - 1.1e-60 204.2 1.4 1.4e-60 204.0 1.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Bax1-I PF01027.20 GAP85485.1 - 9.3e-35 120.3 10.8 1.5e-34 119.7 10.8 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 cNMP_binding PF00027.29 GAP85487.1 - 2.3e-36 123.7 0.0 3.5e-19 68.6 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 GAP85487.1 - 2.6e-31 109.2 7.7 1.5e-30 106.7 8.4 2.0 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein LRR_6 PF13516.6 GAP85487.1 - 1.7e-11 43.2 3.4 0.1 12.7 0.0 6.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 GAP85487.1 - 8.6e-07 29.2 0.0 0.35 11.4 0.0 4.5 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.33 GAP85487.1 - 2.9e-05 23.8 0.7 2.9e-05 23.8 0.7 3.5 5 0 0 5 5 5 1 F-box domain F-box-like PF12937.7 GAP85487.1 - 5.8e-05 22.9 1.8 5.8e-05 22.9 1.8 2.2 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 GAP85487.1 - 0.0096 16.3 7.7 19 6.3 0.0 6.4 9 0 0 9 9 9 1 Leucine Rich Repeat Cupin_3 PF05899.12 GAP85487.1 - 0.21 11.3 0.3 25 4.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) LRR_8 PF13855.6 GAP85487.1 - 0.22 11.3 0.7 16 5.4 0.0 3.5 2 1 2 4 4 4 0 Leucine rich repeat ADH_zinc_N PF00107.26 GAP85488.1 - 1.3e-26 93.1 0.2 1.9e-26 92.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP85488.1 - 2.2e-24 87.0 0.1 3.9e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP85488.1 - 4.2e-05 23.4 0.2 0.00014 21.7 0.2 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FAD_binding_3 PF01494.19 GAP85489.1 - 5.3e-42 144.3 0.0 2e-23 83.2 0.0 2.0 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAP85489.1 - 1.9e-05 24.8 0.0 5.7e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP85489.1 - 0.00087 19.0 0.1 0.027 14.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAP85489.1 - 0.0015 17.3 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAP85489.1 - 0.014 14.6 0.0 0.02 14.2 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP85489.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAP85489.1 - 0.019 14.0 0.4 0.054 12.5 0.4 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAP85489.1 - 0.034 14.7 0.0 0.099 13.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAP85489.1 - 0.05 12.9 0.0 5.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 GAP85489.1 - 0.067 13.2 0.2 0.49 10.4 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 GAP85489.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 GAP85489.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 GAP85490.1 - 1.4e-12 47.3 14.2 1.7e-12 46.9 14.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP85490.1 - 3e-12 46.1 2.9 4.6e-12 45.6 2.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Ank_2 PF12796.7 GAP85491.1 - 1.4e-65 217.9 5.4 9.9e-10 38.9 0.0 11.0 4 3 6 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP85491.1 - 1.4e-50 169.0 8.3 3.3e-10 40.3 0.0 14.7 10 3 7 17 17 17 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP85491.1 - 4.3e-43 140.4 16.8 0.0095 16.4 0.0 18.8 20 1 1 21 21 21 7 Ankyrin repeat Ank_5 PF13857.6 GAP85491.1 - 1.4e-42 143.1 22.9 6.5e-10 39.1 0.0 14.4 9 4 7 16 16 16 11 Ankyrin repeats (many copies) Ank PF00023.30 GAP85491.1 - 7.3e-34 114.7 9.9 0.0049 17.3 0.0 14.5 14 1 0 14 14 14 10 Ankyrin repeat ZZ PF00569.17 GAP85491.1 - 4.1e-07 29.7 12.2 8e-07 28.8 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 GAP85491.1 - 1.9 8.8 13.0 3.9 7.9 13.0 1.5 1 0 0 1 1 1 0 C1 domain Patatin PF01734.22 GAP85492.1 - 2e-16 60.8 0.0 6.1e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase Peptidase_S8 PF00082.22 GAP85492.1 - 1.2e-12 47.7 1.6 6e-12 45.4 1.6 1.9 1 1 0 1 1 1 1 Subtilase family Na_Ca_ex PF01699.24 GAP85493.1 - 1e-24 87.2 33.6 4.2e-16 59.2 8.3 3.3 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 GAP85493.1 - 8.4e-17 61.6 11.6 8.4e-17 61.6 11.6 4.8 6 0 0 6 6 6 1 Inner membrane component domain AAA PF00004.29 GAP85494.1 - 7.7e-44 149.3 0.0 1.3e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAP85494.1 - 1.9e-14 53.2 0.0 4.3e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAP85494.1 - 1e-07 32.0 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAP85494.1 - 1.4e-07 31.8 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAP85494.1 - 4.3e-06 27.2 0.0 0.00011 22.6 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 GAP85494.1 - 5.9e-06 26.1 3.3 1.6e-05 24.8 3.3 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 GAP85494.1 - 2.5e-05 24.6 0.2 0.006 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAP85494.1 - 5.8e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAP85494.1 - 0.00063 20.3 0.1 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 GAP85494.1 - 0.001 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 GAP85494.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 GAP85494.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 GAP85494.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 GAP85494.1 - 0.0081 15.5 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 GAP85494.1 - 0.0081 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 GAP85494.1 - 0.0098 15.5 0.2 0.032 13.9 0.2 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 GAP85494.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GAP85494.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GAP85494.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 GAP85494.1 - 0.023 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 GAP85494.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 GAP85494.1 - 0.031 13.7 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 GAP85494.1 - 0.032 14.0 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAP85494.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAP85494.1 - 0.035 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 GAP85494.1 - 0.05 13.2 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain HR1 PF02185.16 GAP85494.1 - 0.053 13.7 0.9 0.13 12.4 0.9 1.6 1 0 0 1 1 1 0 Hr1 repeat Parvo_NS1 PF01057.17 GAP85494.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 GAP85494.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Y_phosphatase PF00102.27 GAP85495.1 - 3.2e-59 200.4 0.0 3.3e-52 177.4 0.0 3.1 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 GAP85495.1 - 1.6e-11 44.6 0.0 5.1e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 GAP85495.1 - 0.048 13.6 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 GAP85495.1 - 0.068 13.0 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.7 GAP85497.1 - 6.3e-28 96.4 44.2 3.4e-06 27.3 0.7 9.4 4 2 6 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAP85497.1 - 8.6e-23 79.9 42.7 9.1e-07 28.5 2.6 7.2 3 1 5 8 8 8 7 Leucine rich repeat LRR_9 PF14580.6 GAP85497.1 - 7.3e-11 41.9 13.3 5.9e-05 22.6 0.8 5.0 1 1 4 5 5 5 5 Leucine-rich repeat Aspzincin_M35 PF14521.6 GAP85499.1 - 0.0016 19.0 3.4 0.011 16.3 3.4 2.0 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase COesterase PF00135.28 GAP85500.1 - 2.3e-74 251.1 0.0 5.8e-67 226.7 0.0 2.0 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP85500.1 - 9.3e-08 32.2 0.1 2.2e-07 30.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP85500.1 - 0.00032 21.4 3.7 0.0015 19.2 3.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.8 GAP85501.1 - 8.1e-46 156.6 1.1 1.3e-45 155.9 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.21 GAP85502.1 - 7.7e-106 354.5 44.8 9.2e-106 354.3 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP85502.1 - 7e-23 81.1 47.5 8.7e-23 80.8 47.5 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.6 GAP85503.1 - 1.8e-55 188.1 5.8 3.1e-55 187.3 5.8 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP85503.1 - 1.3e-42 145.5 1.8 2.2e-42 144.7 1.8 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP85503.1 - 6.8e-11 42.4 4.7 2.2e-09 37.5 4.7 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP85503.1 - 0.00081 18.9 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAP85503.1 - 0.0015 17.7 0.1 0.0024 17.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Adeno_PIX PF03955.14 GAP85503.1 - 0.0033 17.6 0.0 0.0086 16.2 0.0 1.7 1 0 0 1 1 1 1 Adenovirus hexon-associated protein (IX) Ldh_1_N PF00056.23 GAP85503.1 - 0.017 15.2 0.3 0.1 12.7 0.4 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain FMO-like PF00743.19 GAP85504.1 - 7.2e-11 41.2 0.0 2.1e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 GAP85504.1 - 2.3e-09 37.3 1.4 9e-07 29.0 0.1 3.7 4 1 0 4 4 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAP85504.1 - 1.5e-06 28.3 0.1 0.0055 16.7 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAP85504.1 - 2.1e-06 27.2 0.0 4.3e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP85504.1 - 3.6e-06 26.3 0.0 0.00035 19.8 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAP85504.1 - 8.6e-06 25.2 0.0 0.0017 17.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP85504.1 - 2.2e-05 24.2 1.4 0.044 13.4 0.2 3.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 GAP85504.1 - 0.00012 21.4 0.0 0.00067 19.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Semialdhyde_dh PF01118.24 GAP85504.1 - 0.016 15.7 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAP85504.1 - 0.038 14.1 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 GAP85504.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 GAP85505.1 - 3.3e-48 164.3 5.4 1.8e-47 161.9 5.4 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP85505.1 - 1e-31 109.9 4.4 1.7e-30 106.0 4.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP85505.1 - 1e-08 35.3 5.5 3.5e-08 33.6 5.5 1.8 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAP85505.1 - 0.0057 16.6 0.4 0.0091 15.9 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain V_ATPase_I PF01496.19 GAP85506.1 - 0 1051.8 0.0 0 1051.6 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Golgin_A5 PF09787.9 GAP85506.1 - 0.015 14.8 6.3 0.092 12.2 0.4 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 GAP85506.1 - 0.067 12.1 5.1 2.3 7.0 0.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein CheZ PF04344.13 GAP85506.1 - 0.079 12.9 4.3 0.16 11.8 0.2 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF4382 PF14321.6 GAP85506.1 - 0.09 13.0 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4382) DUF1664 PF07889.12 GAP85506.1 - 0.23 11.5 5.8 2.5 8.2 1.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GAP85506.1 - 0.26 11.3 7.8 1.6 8.8 2.1 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 GAP85506.1 - 0.29 11.4 6.3 0.96 9.8 1.6 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) EzrA PF06160.12 GAP85506.1 - 0.31 9.2 6.1 0.7 8.0 0.4 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Filament PF00038.21 GAP85506.1 - 0.39 10.3 11.7 0.79 9.3 1.3 2.6 2 1 1 3 3 3 0 Intermediate filament protein SesA PF17107.5 GAP85506.1 - 0.41 10.8 2.5 0.82 9.9 0.1 2.5 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Nup54 PF13874.6 GAP85506.1 - 0.44 10.6 4.3 6.3 6.9 0.2 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Prefoldin_2 PF01920.20 GAP85506.1 - 0.5 10.4 5.8 3.7 7.6 0.3 2.9 3 0 0 3 3 3 0 Prefoldin subunit CLZ PF16526.5 GAP85506.1 - 0.53 10.7 8.1 2.9 8.3 1.0 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GAS PF13851.6 GAP85506.1 - 0.6 9.4 5.3 4.9 6.5 0.8 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 GAP85506.1 - 0.63 10.6 4.9 1.2 9.7 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 LXG PF04740.12 GAP85506.1 - 0.65 9.7 5.6 8.8 6.0 0.8 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily BLOC1_2 PF10046.9 GAP85506.1 - 0.66 10.3 6.1 7.7 6.9 0.2 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 GAP85506.1 - 0.71 9.9 4.4 11 6.0 0.1 2.5 2 0 0 2 2 2 0 Laminin Domain II FAM76 PF16046.5 GAP85506.1 - 0.93 8.8 1.7 12 5.1 0.0 2.1 2 0 0 2 2 2 0 FAM76 protein TRPM_tetra PF16519.5 GAP85506.1 - 0.97 9.6 4.4 2.9 8.1 1.2 2.6 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF639 PF04842.12 GAP85506.1 - 1 8.7 4.5 0.3 10.5 0.7 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) WXG100 PF06013.12 GAP85506.1 - 1.1 9.6 4.9 3.3 8.0 0.4 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF4140 PF13600.6 GAP85506.1 - 1.3 9.5 8.5 3.2 8.2 1.8 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HMMR_N PF15905.5 GAP85506.1 - 1.3 8.4 7.0 5.2 6.5 0.4 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SKA2 PF16740.5 GAP85506.1 - 2.1 8.2 7.2 6.5 6.6 1.1 2.9 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Spc24 PF08286.11 GAP85506.1 - 2.9 8.2 5.6 6.6 7.0 0.1 2.7 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 GAP85506.1 - 3.4 8.0 7.1 2.8 8.2 0.9 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlgN PF05130.12 GAP85506.1 - 4.4 7.8 10.0 4.5 7.8 1.5 2.4 2 0 0 2 2 2 0 FlgN protein DivIC PF04977.15 GAP85506.1 - 9.2 6.1 11.9 0.26 11.1 0.4 3.3 3 0 0 3 3 3 0 Septum formation initiator ZapB PF06005.12 GAP85506.1 - 9.9 6.7 12.0 6.8 7.2 1.8 2.5 2 0 0 2 2 2 0 Cell division protein ZapB DUF5305 PF17231.2 GAP85508.1 - 0.008 15.6 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) DUF4366 PF14283.6 GAP85508.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) MGC-24 PF05283.11 GAP85508.1 - 0.014 15.9 8.0 0.025 15.0 8.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 GAP85508.1 - 0.12 12.4 17.4 0.19 11.7 17.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 GAP85508.1 - 3.6 5.6 10.9 4.7 5.2 10.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SUIM_assoc PF16619.5 GAP85509.1 - 0.00081 19.4 0.9 0.0016 18.5 0.9 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GAP85509.1 - 0.075 12.6 3.3 0.099 12.2 3.3 1.1 1 0 0 1 1 1 0 Spt20 family BAT2_N PF07001.11 GAP85509.1 - 0.44 11.0 7.2 0.22 12.0 4.8 1.8 2 0 0 2 2 2 0 BAT2 N-terminus Myb_DNA-binding PF00249.31 GAP85510.1 - 5.5e-06 26.5 0.0 0.0002 21.5 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 GAP85510.1 - 0.068 13.1 0.0 0.068 13.1 0.0 2.2 2 0 0 2 2 2 0 Myb DNA-binding like DUF4632 PF15451.6 GAP85511.1 - 0.62 10.2 9.9 24 5.1 0.0 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4632) DS PF01916.17 GAP85512.1 - 2.1e-131 437.4 0.0 2.5e-131 437.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Pro_isomerase PF00160.21 GAP85513.1 - 3.7e-43 147.5 0.0 6.4e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 GAP85513.1 - 0.008 16.6 0.1 0.008 16.6 0.1 3.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) HSF_DNA-bind PF00447.17 GAP85514.1 - 3.7e-28 98.0 0.5 8.4e-28 96.8 0.5 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding RIH_assoc PF08454.11 GAP85514.1 - 0.0036 17.1 1.2 0.008 16.0 1.2 1.5 1 0 0 1 1 1 1 RyR and IP3R Homology associated Ets PF00178.22 GAP85514.1 - 0.085 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Ets-domain Mod_r PF07200.13 GAP85514.1 - 0.26 11.4 6.0 5.7 7.0 0.0 2.8 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF4140 PF13600.6 GAP85514.1 - 0.38 11.2 4.5 3.4 8.2 0.5 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Phage_HK97_TLTM PF06120.11 GAP85514.1 - 1.1 8.4 4.7 7.1 5.7 2.3 2.4 2 0 0 2 2 2 0 Tail length tape measure protein Nup54 PF13874.6 GAP85514.1 - 1.4 9.0 11.8 0.74 9.9 2.7 2.7 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 DUF2203 PF09969.9 GAP85514.1 - 4.3 8.1 5.4 8.6 7.1 1.4 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) HIP1_clath_bdg PF16515.5 GAP85514.1 - 6.3 7.5 11.9 4.2 8.0 0.8 3.2 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 GAP85514.1 - 8.9 6.8 13.5 4.7 7.7 1.6 3.3 4 0 0 4 4 4 0 Apg6 coiled-coil region ZapB PF06005.12 GAP85514.1 - 9.9 6.7 17.9 10 6.7 3.3 3.3 3 0 0 3 3 3 0 Cell division protein ZapB DoxX_3 PF13781.6 GAP85515.1 - 0.03 14.9 0.3 0.03 14.9 0.3 2.7 2 1 1 3 3 3 0 DoxX-like family TauD PF02668.16 GAP85516.1 - 3.9e-27 95.7 0.0 5.1e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family OTT_1508_deam PF14441.6 GAP85517.1 - 1.1e-20 73.4 2.5 2e-20 72.6 2.5 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF997 PF06196.12 GAP85518.1 - 0.42 10.6 5.1 1.4 9.0 5.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF997) Sec6 PF06046.13 GAP85519.1 - 2.9e-165 550.9 12.2 4.2e-165 550.4 12.2 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 GAP85519.1 - 0.00012 21.2 2.2 0.00012 21.2 2.2 2.4 3 0 0 3 3 3 1 Vps53-like, N-terminal OmdA PF13376.6 GAP85519.1 - 0.05 13.6 1.5 0.27 11.3 0.0 2.8 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated NPV_P10 PF05531.12 GAP85519.1 - 0.16 12.4 3.6 20 5.7 1.2 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Vps5 PF09325.10 GAP85519.1 - 1.9 8.0 8.1 10 5.6 0.1 3.5 3 0 0 3 3 3 0 Vps5 C terminal like DUF745 PF05335.13 GAP85519.1 - 5.2 6.8 7.4 4.5 7.0 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF745) DUF4709 PF15821.5 GAP85519.1 - 5.3 7.4 6.8 48 4.3 0.2 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) Zn_clus PF00172.18 GAP85520.1 - 6.8e-06 26.1 8.0 1.3e-05 25.2 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 GAP85520.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold SPO22 PF08631.10 GAP85521.1 - 8.2e-62 209.2 14.4 8.9e-62 209.1 1.6 3.8 4 0 0 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.17 GAP85521.1 - 0.0028 17.6 0.6 0.12 12.6 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP85521.1 - 0.0099 16.1 1.5 0.06 13.6 0.1 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAP85521.1 - 0.014 15.9 2.4 0.058 13.9 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1487 PF07368.11 GAP85521.1 - 0.022 14.2 0.1 0.044 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) TPR_16 PF13432.6 GAP85521.1 - 0.041 14.5 1.2 40 5.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ATG22 PF11700.8 GAP85522.1 - 9.7e-126 420.2 23.4 1.1e-125 420.0 23.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like SHOCT PF09851.9 GAP85522.1 - 0.052 13.3 0.1 0.082 12.7 0.1 1.3 1 0 0 1 1 1 0 Short C-terminal domain MFS_1 PF07690.16 GAP85524.1 - 2e-31 109.2 37.0 2e-31 109.2 37.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.12 GAP85524.1 - 0.0098 14.5 0.4 0.017 13.7 0.4 1.3 1 0 0 1 1 1 1 Ferroportin1 (FPN1) UXS1_N PF11803.8 GAP85524.1 - 0.34 11.3 1.2 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal PTR2 PF00854.21 GAP85524.1 - 1.2 7.9 6.7 0.11 11.3 1.5 1.9 2 0 0 2 2 2 0 POT family DUF2722 PF10846.8 GAP85525.1 - 1.7e-08 33.9 1.2 8.8e-08 31.5 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2722) DUF5401 PF17380.2 GAP85525.1 - 0.72 7.8 4.5 1.1 7.3 4.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Toxin_11 PF07473.11 GAP85526.1 - 0.059 13.5 1.6 0.14 12.3 1.6 1.6 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species Tir_receptor_N PF07490.11 GAP85526.1 - 0.11 12.3 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus HATPase_c PF02518.26 GAP85527.1 - 3.4e-31 108.1 0.0 7.8e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAP85527.1 - 5.3e-21 74.9 0.1 1.3e-20 73.7 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 GAP85527.1 - 5.9e-19 67.9 0.4 2.3e-18 66.0 0.4 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 GAP85527.1 - 1.1e-12 48.6 0.1 5.3e-12 46.4 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.6 GAP85527.1 - 1.1e-09 38.7 0.0 4.2e-09 36.8 0.0 2.1 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 GAP85527.1 - 1.6e-06 27.7 0.0 3.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 GAP85527.1 - 3.3e-06 27.8 0.0 1.9e-05 25.3 0.0 2.5 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 GAP85527.1 - 5.7e-05 23.0 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 GAP85527.1 - 0.001 18.4 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.6 GAP85527.1 - 0.0092 16.2 1.4 0.0092 16.2 1.4 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat NAD_binding_8 PF13450.6 GAP85528.1 - 3.4e-06 27.2 0.1 6.5e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAP85528.1 - 9e-05 21.9 0.0 0.00023 20.6 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 GAP85528.1 - 0.041 13.9 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 GAP85528.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 GAP85528.1 - 0.11 11.7 0.1 0.26 10.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 GAP85528.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAP85528.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TPT PF03151.16 GAP85529.1 - 1.7e-24 86.7 23.0 2.4e-24 86.2 23.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF5534 PF17686.1 GAP85529.1 - 0.38 11.0 1.1 0.99 9.6 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5534) EamA PF00892.20 GAP85529.1 - 0.97 9.6 39.2 2 8.6 14.4 3.0 3 0 0 3 3 3 0 EamA-like transporter family Ribosomal_L27e PF01777.18 GAP85530.1 - 3e-37 126.8 4.1 4.5e-37 126.3 4.1 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 GAP85530.1 - 0.0068 16.3 0.9 0.018 15.0 0.9 1.7 1 0 0 1 1 1 1 KOW motif TPR_17 PF13431.6 GAP85531.1 - 0.022 15.1 0.0 0.24 11.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase PF00903.25 GAP85532.1 - 1.8e-22 79.9 0.1 2.6e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAP85532.1 - 5.3e-11 42.8 0.0 0.00033 20.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 GAP85532.1 - 2.6e-06 27.7 0.0 0.2 11.8 0.0 3.1 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 GAP85532.1 - 0.12 12.5 0.1 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DHQ_synthase PF01761.20 GAP85532.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase Ssl1 PF04056.14 GAP85533.1 - 7.3e-73 244.5 0.0 9.5e-73 244.1 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 GAP85533.1 - 2.6e-18 66.0 6.5 2.6e-18 66.0 6.5 3.1 3 1 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 GAP85533.1 - 1.2e-14 54.9 0.0 2.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.7 GAP85533.1 - 1.6 8.8 20.0 2.9 8.0 5.7 3.3 2 1 0 2 2 2 0 Double zinc ribbon Chs7 PF12271.8 GAP85534.1 - 4.6e-111 370.8 3.7 5.2e-111 370.6 3.7 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2627 PF11118.8 GAP85534.1 - 1.5 9.4 5.6 4.4 7.9 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2627) Sugar_tr PF00083.24 GAP85535.1 - 2.5e-106 356.2 14.0 3e-106 356.0 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP85535.1 - 6.8e-28 97.6 46.9 1.5e-26 93.2 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAP85535.1 - 6.6e-09 34.8 19.8 9.8e-07 27.7 4.0 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 GAP85535.1 - 0.00011 21.2 9.3 0.011 14.6 0.2 2.4 2 0 0 2 2 2 2 MFS_1 like family MFS_5 PF05631.14 GAP85535.1 - 0.0018 17.2 1.3 0.0018 17.2 1.3 1.5 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM DUF2530 PF10745.9 GAP85535.1 - 0.21 11.9 1.8 2.1 8.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) MFS_3 PF05977.13 GAP85535.1 - 0.29 9.5 4.8 1.8 6.9 0.4 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Aldedh PF00171.22 GAP85536.1 - 3.4e-131 437.9 0.0 4e-131 437.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aminotran_1_2 PF00155.21 GAP85537.1 - 3.7e-66 223.8 0.0 4.2e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAP85537.1 - 0.0005 19.4 0.0 0.00079 18.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAP85537.1 - 0.0013 18.2 0.0 0.003 16.9 0.0 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 GAP85537.1 - 0.0014 17.3 0.1 0.0028 16.2 0.1 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAP85537.1 - 0.0069 15.4 0.1 0.017 14.1 0.1 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DUF2407 PF10302.9 GAP85538.1 - 8.8e-29 100.1 0.0 1.3e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.6 GAP85538.1 - 1.8e-17 63.8 3.6 1.7e-14 54.2 0.4 2.2 1 1 1 2 2 2 2 DUF2407 C-terminal domain ubiquitin PF00240.23 GAP85538.1 - 0.049 13.4 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family Phage_holin_2_1 PF04971.12 GAP85538.1 - 2.4 8.2 8.3 14 5.8 0.3 2.4 2 0 0 2 2 2 0 Bacteriophage P21 holin S rRNA_proc-arch PF13234.6 GAP85539.1 - 1.5e-86 290.6 0.1 3.6e-86 289.4 0.1 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 GAP85539.1 - 2e-51 173.9 2.2 4.6e-51 172.7 0.8 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 GAP85539.1 - 1.2e-19 70.7 0.0 7.9e-19 68.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP85539.1 - 2.2e-07 31.2 0.0 1.4e-06 28.6 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP85539.1 - 8e-06 26.0 0.1 5.1e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 GAP85539.1 - 0.011 15.7 2.0 0.43 10.5 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 GAP85539.1 - 0.022 15.0 0.1 0.23 11.7 0.0 2.7 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 GAP85539.1 - 0.077 12.0 0.0 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Metallophos PF00149.28 GAP85540.1 - 2.8e-13 50.9 0.1 4.7e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAP85540.1 - 2.1e-07 31.3 0.0 6.2e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PPR_2 PF13041.6 GAP85541.1 - 4.5e-17 62.0 0.7 8e-06 26.0 0.1 4.5 3 1 1 4 4 4 4 PPR repeat family PPR PF01535.20 GAP85541.1 - 3.7e-11 42.5 13.4 3.4e-05 23.8 0.1 5.8 5 1 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 GAP85541.1 - 1.9e-06 27.9 0.2 0.005 16.9 0.0 4.3 5 1 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAP85541.1 - 7.5e-06 25.6 5.2 0.17 11.6 0.0 4.7 4 1 0 4 4 4 2 PPR repeat PPR_long PF17177.4 GAP85541.1 - 0.0019 17.6 0.4 0.087 12.2 0.4 2.7 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP MRP-S25 PF13741.6 GAP85542.1 - 2.7e-65 220.1 9.3 4.4e-59 199.8 3.9 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 GAP85542.1 - 2.1e-06 28.0 6.4 2.3e-06 27.9 4.0 2.1 2 1 0 2 2 2 1 Mitochondrial ribosomal protein S23 ADSL_C PF10397.9 GAP85542.1 - 0.042 14.4 0.2 0.11 13.1 0.2 1.7 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminus MIT PF04212.18 GAP85543.1 - 2e-11 43.8 3.9 2.3e-11 43.6 3.9 1.1 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Fungal_trans_2 PF11951.8 GAP85543.1 - 0.0077 15.1 0.2 0.0084 15.0 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_10 PF13374.6 GAP85543.1 - 0.07 13.0 1.3 0.16 11.9 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 GAP85545.1 - 1.5e-45 152.9 0.9 4.6e-21 74.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 GAP85545.1 - 6.8e-23 81.6 0.0 1.9e-22 80.1 0.0 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 GAP85545.1 - 4.5e-05 23.2 0.0 0.34 10.8 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 GAP85545.1 - 0.00032 20.7 0.6 0.017 15.2 0.0 2.9 3 1 0 3 3 3 1 RNA binding motif PHM7_cyt PF14703.6 GAP85545.1 - 0.013 15.7 0.1 0.46 10.7 0.1 3.0 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 GAP85545.1 - 0.017 15.2 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 GAP85545.1 - 0.023 14.3 0.0 0.048 13.3 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.28 GAP85546.1 - 4.4e-18 65.2 2.0 5.5e-18 64.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 GAP85546.1 - 2e-12 47.6 21.3 2e-12 47.6 21.3 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.6 GAP85546.1 - 0.052 13.4 1.5 0.12 12.3 0.5 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Anth_synt_I_N PF04715.13 GAP85546.1 - 0.12 12.6 0.3 0.3 11.3 0.2 1.6 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region Ima1_N PF09779.9 GAP85547.1 - 2.3e-32 112.7 0.1 5.3e-32 111.5 0.1 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain Zn_Tnp_IS1595 PF12760.7 GAP85547.1 - 0.0042 17.0 5.0 0.0091 15.9 5.0 1.6 1 0 0 1 1 1 1 Transposase zinc-ribbon domain HscB_4_cys PF18256.1 GAP85547.1 - 0.072 12.9 7.5 0.51 10.2 0.1 2.6 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Mcm10 PF09332.11 GAP85547.1 - 1.3 8.4 3.3 2.1 7.7 3.3 1.2 1 0 0 1 1 1 0 Mcm10 replication factor Alg14 PF08660.11 GAP85548.1 - 5.7e-42 143.6 0.1 1e-41 142.7 0.1 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF812 PF05667.11 GAP85549.1 - 0.00019 20.5 6.3 0.00035 19.6 6.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AAA_23 PF13476.6 GAP85549.1 - 0.013 16.0 1.6 0.026 15.0 1.6 1.5 1 0 0 1 1 1 0 AAA domain Piezo_RRas_bdg PF12166.8 GAP85549.1 - 0.025 13.9 2.9 0.039 13.2 2.9 1.2 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Caldesmon PF02029.15 GAP85549.1 - 0.76 8.5 20.2 1.2 7.8 20.2 1.2 1 0 0 1 1 1 0 Caldesmon DUF745 PF05335.13 GAP85549.1 - 0.8 9.4 13.7 1.6 8.4 13.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Spc7 PF08317.11 GAP85549.1 - 0.86 8.4 19.9 1.5 7.7 19.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Cauli_AT PF03233.13 GAP85549.1 - 0.95 9.4 4.9 2.1 8.3 4.9 1.6 1 0 0 1 1 1 0 Aphid transmission protein EcoEI_R_C PF08463.10 GAP85549.1 - 1 9.4 8.7 2 8.5 8.2 1.7 1 1 0 1 1 1 0 EcoEI R protein C-terminal Prominin PF05478.11 GAP85549.1 - 1.4 6.8 4.7 1.9 6.3 4.7 1.2 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 GAP85549.1 - 1.4 9.0 10.7 2.8 8.0 10.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KxDL PF10241.9 GAP85549.1 - 1.5 9.1 13.3 2.7 8.3 5.0 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein CorA PF01544.18 GAP85549.1 - 2.3 7.5 5.8 3.8 6.8 5.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein LMBR1 PF04791.16 GAP85549.1 - 7.5 5.3 6.0 14 4.5 6.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 GAP85549.1 - 8.9 4.1 8.5 14 3.4 8.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family adh_short PF00106.25 GAP85551.1 - 1.8e-19 70.0 0.0 3.3e-18 65.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP85551.1 - 3.6e-09 36.5 0.0 5.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP85551.1 - 1.1e-08 35.2 0.1 3.1e-08 33.7 0.0 1.7 1 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAP85551.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein VWA PF00092.28 GAP85552.1 - 0.0019 18.5 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 GAP85552.1 - 0.1 13.2 0.0 0.45 11.2 0.0 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain CPSF73-100_C PF11718.8 GAP85553.1 - 1.9e-88 295.6 0.0 3e-88 295.0 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 GAP85553.1 - 8.2e-29 100.1 0.0 1.7e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 GAP85553.1 - 8.3e-19 68.4 0.6 2.2e-18 67.0 0.6 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 GAP85553.1 - 1.3e-17 63.8 0.1 2.3e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 GAP85553.1 - 2.5e-13 49.8 0.0 5.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 GAP85553.1 - 2.1e-05 24.5 0.1 6e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 GAP85553.1 - 2.1e-05 24.1 0.5 8e-05 22.2 0.7 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain TAF4 PF05236.14 GAP85554.1 - 1.7e-24 87.0 0.5 2.4e-17 63.6 0.2 2.8 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CN_hydrolase PF00795.22 GAP85555.1 - 2.5e-39 135.2 0.0 3.9e-23 82.1 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase SR-25 PF10500.9 GAP85555.1 - 0.0014 18.3 7.5 0.0021 17.7 7.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein LSM14 PF12701.7 GAP85556.1 - 8.1e-31 106.0 0.2 1.2e-30 105.4 0.2 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 GAP85556.1 - 9.7e-16 58.5 7.4 9.7e-16 58.5 7.4 2.7 3 1 0 3 3 3 1 FDF domain SM-ATX PF14438.6 GAP85556.1 - 5e-08 33.0 0.0 9.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain SOG2 PF10428.9 GAP85556.1 - 1.4 8.0 8.9 2.2 7.4 8.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein zf-HIT PF04438.16 GAP85557.1 - 3.5e-09 36.4 9.8 5.4e-09 35.8 9.8 1.3 1 0 0 1 1 1 1 HIT zinc finger Glyco_transf_8 PF01501.20 GAP85558.1 - 1.2e-12 47.9 0.1 2.6e-12 46.9 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAP85558.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative Ala_racemase_N PF01168.20 GAP85559.1 - 3.8e-19 69.2 0.0 5.1e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 GAP85561.1 - 1.7e-121 406.3 5.3 2.1e-121 406.1 5.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 GAP85561.1 - 6.3e-46 155.2 0.0 1.6e-45 153.9 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 GAP85561.1 - 4.1e-16 59.3 0.0 7.4e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Parvo_coat PF00740.18 GAP85561.1 - 0.21 10.2 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Membrane_bind PF14564.6 GAP85563.1 - 1.4e-09 38.4 0.0 0.00063 20.2 0.0 2.4 1 1 1 2 2 2 2 Membrane binding Crystall_3 PF08964.10 GAP85563.1 - 1.7e-08 34.5 0.0 3.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall PF00030.19 GAP85563.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin Methyltransf_11 PF08241.12 GAP85564.1 - 5.2e-10 39.8 0.0 1.2e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP85564.1 - 7.4e-10 38.9 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP85564.1 - 1.2e-08 35.5 0.0 2.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP85564.1 - 1.2e-07 32.4 0.0 4.3e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP85564.1 - 7.1e-06 25.9 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP85564.1 - 0.067 12.5 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family P16-Arc PF04699.14 GAP85565.1 - 3.7e-50 170.3 0.0 4.3e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) SOCS PF12610.8 GAP85566.1 - 0.16 12.4 0.8 0.26 11.7 0.8 1.4 1 1 0 1 1 1 0 Suppressor of cytokine signalling CDC45 PF02724.14 GAP85567.1 - 0.031 12.6 12.6 0.0038 15.6 8.0 1.7 2 0 0 2 2 2 0 CDC45-like protein RRN3 PF05327.11 GAP85567.1 - 0.064 11.8 16.3 0.005 15.5 11.1 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 GAP85567.1 - 0.7 7.9 37.0 0.18 9.9 34.0 1.4 2 0 0 2 2 2 0 DNA polymerase phi Peptidase_S8 PF00082.22 GAP85568.1 - 1.2e-10 41.1 0.0 4.5e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 Subtilase family Tcf25 PF04910.14 GAP85570.1 - 5.5e-58 196.7 0.0 7.3e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 CENP-X PF09415.10 GAP85570.1 - 0.014 15.7 0.1 0.039 14.3 0.1 1.8 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Nop53 PF07767.11 GAP85570.1 - 0.31 10.4 14.3 0.034 13.5 8.5 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) YL1 PF05764.13 GAP85570.1 - 0.77 9.8 18.7 0.05 13.7 11.2 2.2 2 0 0 2 2 2 0 YL1 nuclear protein BUD22 PF09073.10 GAP85570.1 - 6 6.1 31.4 0.53 9.6 20.2 2.2 2 0 0 2 2 2 0 BUD22 HMA PF00403.26 GAP85571.1 - 1.9e-14 53.8 0.6 2.4e-14 53.5 0.6 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 GAP85571.1 - 0.067 13.6 0.1 0.15 12.4 0.1 1.6 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DUF211 PF02680.14 GAP85571.1 - 0.095 12.9 0.1 0.15 12.2 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 Fungal_trans PF04082.18 GAP85572.1 - 2.8e-18 65.9 0.2 4.7e-18 65.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85572.1 - 6.5e-07 29.4 11.3 1.6e-06 28.1 11.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IRK_N PF08466.10 GAP85573.1 - 0.016 15.4 0.0 0.05 13.7 0.0 1.8 1 0 0 1 1 1 0 Inward rectifier potassium channel N-terminal CorA PF01544.18 GAP85573.1 - 0.13 11.6 0.7 0.29 10.4 0.1 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Sugar_tr PF00083.24 GAP85574.1 - 5.2e-84 282.7 16.3 6e-84 282.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP85574.1 - 5e-13 48.7 33.1 2.9e-12 46.2 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4418 PF14387.6 GAP85574.1 - 5.3 7.3 7.5 8.9 6.6 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4418) Thiolase_N PF00108.23 GAP85577.1 - 2.8e-15 56.4 0.1 1.8e-14 53.8 0.0 2.2 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAP85577.1 - 5.2e-11 42.3 2.1 7.2e-11 41.8 0.4 2.2 2 1 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 GAP85577.1 - 4.4e-05 23.2 0.2 0.0026 17.6 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 GAP85577.1 - 0.0012 18.5 0.1 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AAA PF00004.29 GAP85578.1 - 1.1e-49 168.2 0.0 4.9e-38 130.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAP85578.1 - 2e-08 33.9 0.1 4.4e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain ATPase_2 PF01637.18 GAP85578.1 - 2.3e-08 34.3 0.1 0.015 15.2 0.0 4.1 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GAP85578.1 - 6.7e-08 33.1 0.0 0.0028 18.0 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAP85578.1 - 1.4e-07 31.8 0.0 0.00089 19.5 0.0 3.7 2 2 1 3 3 3 1 AAA domain AAA_5 PF07728.14 GAP85578.1 - 2.6e-07 30.7 0.0 0.0012 18.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 GAP85578.1 - 1.7e-06 27.5 0.0 0.054 12.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 GAP85578.1 - 3.5e-06 27.1 0.0 0.02 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 GAP85578.1 - 9e-06 25.4 0.3 0.00022 20.9 0.1 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 GAP85578.1 - 1e-05 25.7 0.0 0.00023 21.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 GAP85578.1 - 2e-05 25.1 0.0 0.089 13.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 GAP85578.1 - 4.4e-05 23.7 0.0 0.26 11.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAP85578.1 - 0.00024 21.5 0.0 0.24 11.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 GAP85578.1 - 0.00024 20.9 0.2 0.12 12.2 0.1 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 GAP85578.1 - 0.00037 20.0 0.4 0.006 16.0 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAP85578.1 - 0.0021 17.8 0.0 0.61 9.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 GAP85578.1 - 0.0031 17.5 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAP85578.1 - 0.0033 17.0 0.3 0.14 11.7 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 GAP85578.1 - 0.0061 16.3 0.1 0.038 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAP85578.1 - 0.0089 16.0 2.2 6.1 6.7 0.1 3.4 4 0 0 4 4 3 0 NACHT domain ATPase PF06745.13 GAP85578.1 - 0.01 15.2 0.1 0.023 14.1 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 GAP85578.1 - 0.011 16.0 0.0 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAP85578.1 - 0.029 14.1 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 GAP85578.1 - 0.066 13.7 0.2 0.66 10.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 GAP85578.1 - 0.078 12.5 0.5 3.4 7.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 GAP85578.1 - 0.11 11.6 0.1 1.9 7.6 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain PhoH PF02562.16 GAP85578.1 - 0.13 11.7 0.1 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 GAP85578.1 - 0.14 11.2 0.1 1.4 7.9 0.1 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 GAP85578.1 - 0.17 12.3 0.1 25 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 GAP85578.1 - 0.18 11.0 0.0 3.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.6 GAP85578.1 - 0.18 11.5 0.1 0.46 10.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain DEAD PF00270.29 GAP85579.1 - 9.5e-11 41.8 0.0 1.1e-09 38.4 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAP85579.1 - 8.6e-09 35.6 0.0 7.6e-08 32.5 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAP85579.1 - 3.8e-06 27.2 0.0 1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Defensin_3 PF08131.11 GAP85579.1 - 0.093 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Defensin-like peptide family F-box-like PF12937.7 GAP85580.1 - 0.0013 18.6 0.0 0.0055 16.6 0.0 2.0 2 1 0 2 2 2 1 F-box-like COesterase PF00135.28 GAP85581.1 - 1e-82 278.7 0.0 1.3e-82 278.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP85581.1 - 3.5e-06 27.0 0.1 2.5e-05 24.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 GAP85584.1 - 3.5e-12 45.9 28.4 3.5e-12 45.9 28.4 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 GAP85584.1 - 5.1e-05 22.9 4.7 0.00013 21.5 4.7 1.7 1 1 0 1 1 1 1 Nodulin-like 7tm_7 PF08395.12 GAP85584.1 - 0.14 11.4 0.2 0.35 10.0 0.2 1.6 1 0 0 1 1 1 0 7tm Chemosensory receptor F-box-like PF12937.7 GAP85585.1 - 0.0013 18.6 0.1 0.0025 17.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 GAP85586.1 - 1.4e-36 125.0 0.0 2.4e-10 40.8 0.0 5.4 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP85586.1 - 1.6e-26 89.4 11.6 0.00092 19.5 0.0 9.1 10 0 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 GAP85586.1 - 1.5e-25 88.5 5.5 9.7e-06 25.8 0.1 8.6 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 GAP85586.1 - 1.7e-23 82.7 6.2 5.3e-08 33.3 0.3 6.5 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP85586.1 - 1.8e-22 79.1 7.7 3.5e-07 30.4 0.1 8.0 6 1 3 9 9 9 5 Ankyrin repeats (many copies) HET PF06985.11 GAP85586.1 - 1.8e-09 38.1 2.6 3.8e-09 37.0 2.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MAPEG PF01124.18 GAP85587.1 - 7.2e-16 58.3 0.8 8.2e-16 58.1 0.8 1.1 1 0 0 1 1 1 1 MAPEG family Fungal_trans PF04082.18 GAP85588.1 - 6.3e-15 54.9 0.8 9.9e-15 54.3 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85588.1 - 1.4e-06 28.4 7.6 2.8e-06 27.4 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cut8 PF08559.10 GAP85588.1 - 0.027 14.1 1.8 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein Hepatitis_core PF00906.20 GAP85588.1 - 1.8 8.1 6.0 1.9 8.0 0.1 2.2 2 0 0 2 2 2 0 Hepatitis core antigen Phosphoesterase PF04185.14 GAP85589.1 - 7e-25 88.0 0.3 4.9e-24 85.2 0.3 2.0 1 1 0 1 1 1 1 Phosphoesterase family DUF1115 PF06544.12 GAP85590.1 - 0.0026 17.9 0.0 0.0042 17.2 0.0 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1115) DUF2066 PF09839.9 GAP85590.1 - 0.095 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) Glyco_hydro_61 PF03443.14 GAP85591.1 - 3.6e-53 180.5 0.1 5.6e-53 179.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 GAP85591.1 - 2.6e-08 33.7 13.0 2.6e-08 33.7 13.0 3.7 3 1 0 3 3 3 1 Fungal cellulose binding domain Tetraspanin PF00335.20 GAP85593.1 - 5.7e-09 36.0 0.3 8.2e-09 35.5 0.3 1.1 1 0 0 1 1 1 1 Tetraspanin family Como_LCP PF02247.16 GAP85593.1 - 0.12 10.9 0.3 0.26 9.8 0.3 1.5 1 1 0 1 1 1 0 Large coat protein DUF308 PF03729.13 GAP85594.1 - 0.0012 19.1 11.0 0.0012 19.1 11.0 3.2 3 0 0 3 3 3 1 Short repeat of unknown function (DUF308) DPM2 PF07297.12 GAP85594.1 - 0.02 15.2 0.4 2.8 8.3 0.6 2.7 1 1 1 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) SAYSvFN PF10260.9 GAP85594.1 - 0.049 13.6 3.1 0.56 10.2 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) An_peroxidase PF03098.15 GAP85595.1 - 1.5e-32 112.9 0.0 4.8e-25 88.1 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 GAP85595.1 - 1.8e-07 30.3 0.0 3.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.9 GAP85596.1 - 4.5e-84 282.2 0.1 6.1e-84 281.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Pec_lyase_C PF00544.19 GAP85598.1 - 1.6e-38 132.4 7.4 2.3e-38 131.9 7.4 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GAP85598.1 - 0.0009 19.1 11.9 0.005 16.7 4.4 2.3 1 1 1 2 2 2 2 Right handed beta helix region Phage_attach PF05354.11 GAP85598.1 - 0.025 14.4 0.6 0.064 13.1 0.6 1.6 1 0 0 1 1 1 0 Phage Head-Tail Attachment PSII_Ycf12 PF05969.11 GAP85598.1 - 0.11 12.4 1.1 0.3 11.1 1.1 1.7 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 Ge1_WD40 PF16529.5 GAP85599.1 - 0.011 14.8 0.1 0.41 9.6 0.0 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BC10 PF06726.12 GAP85600.1 - 1.8e-17 63.3 11.3 3.5e-17 62.4 11.3 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Cellulase PF00150.18 GAP85601.1 - 4e-08 33.0 0.0 1.8e-06 27.6 0.0 2.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PP2C PF00481.21 GAP85602.1 - 3.8e-43 148.0 0.0 6.8e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAP85602.1 - 0.00033 20.6 0.0 0.28 11.1 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 GAP85602.1 - 0.0028 17.3 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF2014 PF09427.10 GAP85602.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) DUF5572 PF17733.1 GAP85603.1 - 8.9e-15 54.3 0.3 1.8e-14 53.3 0.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) SelP_N PF04592.14 GAP85604.1 - 0.037 13.4 7.6 0.054 12.9 7.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAD_binding_4 PF01565.23 GAP85605.1 - 4.6e-21 75.0 1.4 3.5e-20 72.2 2.3 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAP85605.1 - 3.3e-13 49.5 1.0 6.5e-13 48.6 1.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 GAP85605.1 - 0.087 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding PhnA PF03831.14 GAP85605.1 - 0.14 12.0 0.0 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 PhnA domain adh_short PF00106.25 GAP85607.1 - 8.8e-24 84.0 0.1 1.1e-23 83.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP85607.1 - 7.3e-16 58.4 0.0 9.4e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP85607.1 - 1.4e-07 31.6 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAP85607.1 - 0.00019 20.7 0.0 0.00025 20.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 GAP85607.1 - 0.0029 17.7 0.1 0.0054 16.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 GAP85607.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain p450 PF00067.22 GAP85608.1 - 2.2e-41 142.1 0.0 2.8e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 GAP85609.1 - 1.7e-21 76.5 3.5 1.7e-21 76.5 3.5 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAP85609.1 - 9.5e-10 38.4 0.2 1.9e-09 37.4 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 GAP85610.1 - 1.9e-48 165.4 0.0 2.3e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CorA PF01544.18 GAP85611.1 - 9.2e-07 28.5 4.2 5.3e-06 26.0 0.0 2.9 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein Ank_2 PF12796.7 GAP85611.1 - 2.5e-05 24.8 0.0 0.0023 18.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP85611.1 - 0.00038 20.7 0.3 0.057 13.8 0.1 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) YgaB PF14182.6 GAP85611.1 - 0.013 15.9 2.5 0.054 13.9 2.5 2.1 1 0 0 1 1 1 0 YgaB-like protein APP_E2 PF12925.7 GAP85611.1 - 0.015 15.0 0.3 0.096 12.4 0.0 2.3 1 1 1 2 2 2 0 E2 domain of amyloid precursor protein Ank_4 PF13637.6 GAP85611.1 - 0.052 14.2 0.7 1 10.0 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) ACBP PF00887.19 GAP85612.1 - 1.4e-23 82.9 0.0 2.9e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein CYTH PF01928.21 GAP85613.1 - 4.1e-06 26.9 1.6 1.1e-05 25.4 0.3 2.2 3 0 0 3 3 3 1 CYTH domain Radical_SAM PF04055.21 GAP85614.1 - 1.1e-15 58.5 1.7 2.3e-15 57.4 1.6 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GAP85614.1 - 9.4e-07 29.2 0.4 9.4e-07 29.2 0.4 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 GAP85614.1 - 3.2e-06 27.3 0.3 6.1e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain NIF PF03031.18 GAP85614.1 - 0.14 11.9 0.2 0.4 10.4 0.1 1.7 1 1 0 2 2 2 0 NLI interacting factor-like phosphatase ADK PF00406.22 GAP85615.1 - 4.4e-17 62.6 0.0 6e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAP85615.1 - 1.8e-14 54.3 0.0 2.7e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAP85615.1 - 2.1e-07 31.6 0.0 5.3e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAP85615.1 - 1.9e-05 24.1 0.1 0.00095 18.5 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 GAP85615.1 - 0.00027 21.1 0.2 0.0012 19.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP85615.1 - 0.00093 19.6 0.0 0.0013 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP85615.1 - 0.0011 19.3 0.1 0.0032 17.8 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 GAP85615.1 - 0.0034 17.8 0.0 0.0065 16.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 GAP85615.1 - 0.008 16.1 0.0 0.01 15.8 0.0 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 GAP85615.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 GAP85615.1 - 0.013 15.4 0.1 0.21 11.5 0.1 2.1 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 GAP85615.1 - 0.02 15.4 0.0 0.023 15.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.17 GAP85615.1 - 0.027 14.2 0.5 2 8.0 0.1 2.7 2 1 0 2 2 2 0 Thymidylate kinase NB-ARC PF00931.22 GAP85615.1 - 0.041 13.1 0.0 0.092 11.9 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain RNA12 PF10443.9 GAP85615.1 - 0.055 12.2 0.0 0.29 9.8 0.0 1.8 2 0 0 2 2 2 0 RNA12 protein Ploopntkinase3 PF18751.1 GAP85615.1 - 0.059 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 GAP85615.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF5623 PF18536.1 GAP85615.1 - 0.12 12.7 0.1 1.1 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) Sigma54_activat PF00158.26 GAP85615.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 GAP85615.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 GAP85615.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 GAP85615.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAP85615.1 - 0.24 11.1 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ribonuclease_3 PF00636.26 GAP85617.1 - 4.7e-16 59.3 0.1 2.7e-15 56.9 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 GAP85617.1 - 1.1e-09 38.5 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like MRP-S33 PF08293.11 GAP85618.1 - 1e-31 109.0 0.1 1.2e-31 108.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.19 GAP85619.1 - 6.9e-38 126.2 0.9 1e-05 25.0 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat RasGEF PF00617.19 GAP85619.1 - 0.038 14.2 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 RasGEF domain Molybdopterin PF00384.22 GAP85620.1 - 5.6e-67 226.6 0.0 1.5e-33 116.4 0.0 2.1 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 GAP85620.1 - 2.6e-20 72.2 0.2 7.6e-20 70.7 0.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 GAP85620.1 - 1.5e-17 64.0 0.0 3.7e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 GAP85620.1 - 7.9e-17 60.5 0.2 7.9e-17 60.5 0.2 2.1 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 GAP85620.1 - 1.1e-08 34.9 0.6 1.1e-08 34.9 0.6 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 GAP85620.1 - 0.028 14.2 0.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ketoacyl-synt PF00109.26 GAP85621.1 - 9.5e-74 248.2 0.1 5.8e-73 245.6 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAP85621.1 - 1.5e-51 175.8 0.0 2.7e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 GAP85621.1 - 1.7e-49 168.2 0.0 6.8e-49 166.2 0.0 2.2 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 GAP85621.1 - 4.7e-43 147.5 0.0 7.4e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAP85621.1 - 1.3e-36 125.2 0.0 5.1e-36 123.3 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAP85621.1 - 9.9e-21 74.3 0.0 4e-20 72.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 GAP85621.1 - 1.4e-16 61.7 0.0 1.9e-14 54.8 0.0 3.2 3 0 0 3 3 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 GAP85621.1 - 6.7e-16 58.7 0.0 6.9e-11 42.6 0.0 3.0 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 GAP85621.1 - 8.1e-15 55.0 0.9 5.4e-14 52.3 0.1 2.9 4 0 0 4 4 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 GAP85621.1 - 7.2e-13 48.7 0.0 2.2e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP85621.1 - 2.5e-12 47.3 0.0 9.6e-12 45.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP85621.1 - 7e-12 45.8 0.0 2.6e-11 44.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP85621.1 - 3.8e-10 39.8 0.0 1.4e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP85621.1 - 1.9e-08 33.9 0.0 3.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short PF00106.25 GAP85621.1 - 6.4e-07 29.0 0.6 6.4e-06 25.8 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase ADH_N PF08240.12 GAP85621.1 - 8e-06 25.7 0.1 1.8e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 GAP85621.1 - 0.00024 20.6 0.0 0.00074 19.0 0.0 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain DREV PF05219.12 GAP85621.1 - 0.0024 17.0 0.0 0.0055 15.8 0.0 1.5 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_24 PF13578.6 GAP85621.1 - 0.015 16.3 0.0 0.048 14.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain PP-binding PF00550.25 GAP85621.1 - 0.018 15.4 0.0 0.051 13.9 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_8 PF05148.15 GAP85621.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase PCMT PF01135.19 GAP85621.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Peptidase_M15_4 PF13539.6 GAP85621.1 - 0.11 13.1 0.1 0.39 11.3 0.1 2.0 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase ILVD_EDD PF00920.21 GAP85622.1 - 1.1e-87 294.9 0.7 4.6e-84 282.9 0.3 2.1 2 0 0 2 2 2 2 Dehydratase family CENP-F_N PF10481.9 GAP85622.1 - 0.03 14.0 0.2 0.041 13.5 0.2 1.1 1 0 0 1 1 1 0 Cenp-F N-terminal domain SHOCT PF09851.9 GAP85622.1 - 0.032 14.0 0.3 0.41 10.5 0.0 2.6 2 0 0 2 2 2 0 Short C-terminal domain DUF1611_N PF17396.2 GAP85622.1 - 0.033 14.4 0.2 0.23 11.7 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_N) Rossmann-like domain DUF1465 PF07323.12 GAP85622.1 - 0.055 13.3 0.2 0.098 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) PspB PF06667.12 GAP85622.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B XRCC4 PF06632.12 GAP85625.1 - 2e-06 26.9 10.2 4.9e-06 25.6 10.2 1.8 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3584 PF12128.8 GAP85625.1 - 0.0093 13.5 0.6 0.012 13.2 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) FlxA PF14282.6 GAP85625.1 - 0.18 11.8 4.0 0.17 11.9 1.0 2.3 2 0 0 2 2 2 0 FlxA-like protein Aldo_ket_red PF00248.21 GAP85626.1 - 3.3e-36 125.0 0.0 6e-35 120.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.14 GAP85627.1 - 1.3e-124 416.6 0.0 1.6e-124 416.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family PAP2 PF01569.21 GAP85628.1 - 9.1e-23 80.5 3.4 2e-22 79.4 3.4 1.6 1 0 0 1 1 1 1 PAP2 superfamily Fungal_trans_2 PF11951.8 GAP85629.1 - 2.8e-17 62.6 0.0 2.2e-09 36.7 0.0 3.1 2 1 1 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85629.1 - 1.6e-07 31.3 8.3 3.6e-07 30.2 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 GAP85630.1 - 1.8e-07 31.0 0.0 2.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP85630.1 - 2.3e-07 30.5 0.0 2.3e-06 27.2 0.1 2.2 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 GAP85630.1 - 0.0042 16.6 0.0 0.055 12.9 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAP85630.1 - 0.0094 15.1 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain LigB PF02900.18 GAP85631.1 - 2.9e-32 111.8 0.0 3.9e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase His_Phos_1 PF00300.22 GAP85632.1 - 3.9e-16 59.3 0.4 5.2e-16 58.9 0.4 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AlcCBM31 PF11606.8 GAP85633.1 - 0.052 13.7 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein DUF2681 PF10883.8 GAP85633.1 - 0.12 12.7 0.0 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Acetyltransf_7 PF13508.7 GAP85634.1 - 3.9e-05 24.0 0.0 6.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP85634.1 - 0.0012 18.8 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAP85634.1 - 0.0016 18.4 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP85634.1 - 0.0034 17.5 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP85634.1 - 0.0046 17.2 0.0 0.0083 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Abhydrolase_1 PF00561.20 GAP85635.1 - 2.7e-18 66.6 0.0 4.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 GAP85635.1 - 7.6e-18 64.5 0.1 2.2e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein SET PF00856.28 GAP85636.1 - 4.8e-07 30.3 0.0 2.7e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 SET domain FeS PF04060.13 GAP85636.1 - 7.6 6.3 8.7 0.37 10.5 2.6 1.9 2 0 0 2 2 2 0 Putative Fe-S cluster Methyltr_RsmB-F PF01189.17 GAP85637.1 - 2.2e-70 236.4 0.0 3.6e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 GAP85637.1 - 1.7e-08 34.8 0.0 5.4e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_25 PF13649.6 GAP85637.1 - 0.015 16.0 0.0 0.037 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Blt1 PF12754.7 GAP85638.1 - 1.8e-36 125.7 0.1 2.4e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 GAP85638.1 - 2.4e-18 65.5 0.1 3.9e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 GAP85638.1 - 0.026 14.3 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family Cofilin_ADF PF00241.20 GAP85639.1 - 4.1e-39 133.1 0.0 4.6e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.24 GAP85640.1 - 1.9e-88 297.3 10.2 3.5e-88 296.4 10.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 GAP85640.1 - 0.083 13.3 0.1 0.27 11.6 0.1 1.9 1 0 0 1 1 1 0 Transcriptional regulator adh_short PF00106.25 GAP85641.1 - 3.4e-14 52.8 0.0 9.7e-13 48.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP85641.1 - 6.1e-05 22.7 0.0 0.00018 21.1 0.0 1.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase CDCA PF18484.1 GAP85641.1 - 0.0085 16.0 0.0 0.024 14.5 0.0 1.6 1 1 1 2 2 2 1 Cadmium carbonic anhydrase repeat BPL_LplA_LipB PF03099.19 GAP85643.1 - 5.3e-06 26.4 0.0 3e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF3439 PF11921.8 GAP85643.1 - 0.33 10.9 5.1 1.4 8.9 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Clathrin PF00637.20 GAP85644.1 - 9.6e-24 83.9 3.9 1.1e-21 77.1 4.1 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 GAP85644.1 - 4.5e-15 55.6 0.2 2.5e-14 53.2 0.2 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 GAP85644.1 - 2.2e-07 30.8 2.6 2.2e-07 30.8 2.6 2.0 2 0 0 2 2 2 1 Zinc-finger zf-RING_5 PF14634.6 GAP85644.1 - 0.00057 19.8 1.1 0.0011 18.8 1.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.6 GAP85644.1 - 0.00086 18.9 0.0 0.0029 17.2 0.0 1.9 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.6 GAP85644.1 - 0.0027 18.4 1.0 5.4 8.1 0.0 4.0 3 1 1 4 4 3 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 GAP85644.1 - 0.005 17.2 2.0 0.014 15.7 2.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAP85644.1 - 0.0058 16.4 5.8 0.025 14.4 5.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAP85644.1 - 0.0063 16.5 0.9 0.016 15.2 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 GAP85644.1 - 0.012 15.8 1.6 0.029 14.6 1.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAP85644.1 - 0.018 15.1 3.8 0.047 13.7 3.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger TPR_2 PF07719.17 GAP85644.1 - 0.072 13.2 2.2 0.3 11.3 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF4810 PF16068.5 GAP85644.1 - 0.085 13.4 0.2 19 5.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) zf-C3HC4 PF00097.25 GAP85644.1 - 0.1 12.5 0.9 0.26 11.2 0.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ANAPC3 PF12895.7 GAP85644.1 - 0.65 10.3 4.4 10 6.4 0.2 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-C3HC4_4 PF15227.6 GAP85644.1 - 0.66 10.2 1.9 1.5 9.1 1.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DAG1 PF05454.11 GAP85644.1 - 1 8.7 3.7 1.7 8.0 3.7 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) HATPase_c_3 PF13589.6 GAP85645.1 - 3.4e-16 59.3 0.0 6.6e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 GAP85645.1 - 9.5e-07 28.7 0.0 2.5e-05 24.1 0.0 2.5 1 1 1 2 2 2 1 MutL C terminal dimerisation domain CN_hydrolase PF00795.22 GAP85647.1 - 1.7e-28 99.7 0.1 1.4e-21 77.0 0.1 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase CFEM PF05730.11 GAP85648.1 - 1e-08 35.1 2.4 2.3e-08 34.0 2.4 1.6 1 1 0 1 1 1 1 CFEM domain NACHT_N PF17100.5 GAP85649.1 - 3.7e-21 76.0 2.1 3.7e-21 76.0 2.1 3.0 3 1 1 4 4 4 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 GAP85649.1 - 6.2e-13 49.1 0.2 0.00018 22.0 0.0 6.1 2 2 3 7 7 7 3 Ankyrin repeats (3 copies) NACHT PF05729.12 GAP85649.1 - 3.8e-05 23.7 0.0 0.00012 22.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.6 GAP85649.1 - 0.00011 22.3 0.2 0.47 11.2 0.0 5.7 7 0 0 7 7 4 1 Ankyrin repeat Ank PF00023.30 GAP85649.1 - 0.0021 18.5 0.3 1.9 9.1 0.0 5.3 6 0 0 6 6 6 1 Ankyrin repeat KAP_NTPase PF07693.14 GAP85649.1 - 0.0039 16.5 0.1 0.42 9.8 0.0 2.9 1 1 1 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.6 GAP85649.1 - 0.0048 17.3 1.0 0.039 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Peptidase_M99 PF17033.5 GAP85649.1 - 0.038 13.4 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic Ank_4 PF13637.6 GAP85649.1 - 0.038 14.6 0.0 0.61 10.7 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP85649.1 - 0.14 12.5 0.0 0.87 10.0 0.0 2.4 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Med30 PF11315.8 GAP85649.1 - 0.2 11.8 6.8 2.2 8.5 2.8 2.6 2 0 0 2 2 2 0 Mediator complex subunit 30 CpxA_peri PF16527.5 GAP85649.1 - 0.33 11.3 2.8 3.4 8.0 2.8 2.6 3 0 0 3 3 3 0 Two-component sensor protein CpxA, periplasmic domain DUF4047 PF13256.6 GAP85649.1 - 0.79 9.9 5.4 2.1 8.5 5.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF3837 PF12939.7 GAP85649.1 - 4 7.9 8.0 4.4 7.8 3.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) eIF3_N PF09440.10 GAP85649.1 - 9.3 6.7 8.3 3.5 8.1 4.2 2.4 3 0 0 3 3 2 0 eIF3 subunit 6 N terminal domain Ribonuc_red_lgC PF02867.15 GAP85650.1 - 1.2e-190 634.5 0.0 1.6e-190 634.1 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 GAP85650.1 - 9.4e-24 83.2 0.0 3.3e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 GAP85650.1 - 1.5e-16 60.7 0.0 3.6e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain adh_short_C2 PF13561.6 GAP85651.1 - 9.8e-55 185.6 1.9 1.1e-54 185.4 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP85651.1 - 7.9e-41 139.7 1.3 1e-40 139.3 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP85651.1 - 3.3e-13 50.0 0.3 4.8e-13 49.4 0.3 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAP85651.1 - 0.031 13.6 0.2 0.066 12.5 0.1 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 GAP85651.1 - 0.043 13.3 0.2 0.071 12.6 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Amidase02_C PF12123.8 GAP85651.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DRTGG PF07085.12 GAP85651.1 - 0.12 12.2 0.4 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 DRTGG domain TatD_DNase PF01026.21 GAP85652.1 - 4.7e-40 137.6 0.0 4.8e-39 134.3 0.0 2.0 1 1 0 1 1 1 1 TatD related DNase CENP-N PF05238.13 GAP85653.1 - 6.6e-137 457.2 0.0 8e-137 456.9 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.15 GAP85654.1 - 3.4e-11 43.0 11.0 6.2e-11 42.2 11.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAP85654.1 - 0.00016 21.7 9.5 0.00029 20.9 9.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.11 GAP85654.1 - 0.0014 18.4 0.4 0.0028 17.5 0.4 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region XhlA PF10779.9 GAP85654.1 - 0.025 14.8 1.0 0.046 13.9 1.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Prefoldin_2 PF01920.20 GAP85654.1 - 0.039 13.9 1.0 0.065 13.2 1.0 1.3 1 0 0 1 1 1 0 Prefoldin subunit TSC22 PF01166.18 GAP85654.1 - 0.057 13.7 0.4 0.1 12.9 0.4 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family GIT_CC PF16559.5 GAP85654.1 - 0.061 13.2 0.8 0.098 12.5 0.2 1.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HET PF06985.11 GAP85656.1 - 3.6e-25 89.0 0.1 8.2e-25 87.9 0.1 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) WSC PF01822.19 GAP85657.1 - 9.8e-33 112.2 24.6 3.9e-18 65.4 10.6 2.5 2 0 0 2 2 2 2 WSC domain Glyoxal_oxid_N PF07250.11 GAP85657.1 - 1.6e-26 93.0 0.0 1.5e-25 89.9 0.0 2.3 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 GAP85657.1 - 5.8e-23 81.0 0.0 1.2e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) p450 PF00067.22 GAP85658.1 - 6.4e-53 180.1 0.0 7.6e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.9 GAP85659.1 - 4.9e-23 81.9 0.0 8e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.23 GAP85659.1 - 4.3e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP85659.1 - 0.00045 20.2 0.2 0.0017 18.3 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 GAP85659.1 - 0.0011 18.4 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Septin Roc PF08477.13 GAP85659.1 - 0.0011 19.2 0.1 0.0033 17.6 0.1 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP85659.1 - 0.0059 16.1 0.2 0.91 9.0 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AIG1 PF04548.16 GAP85659.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Gtr1_RagA PF04670.12 GAP85659.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 GAP85659.1 - 0.032 13.8 0.4 0.11 12.1 0.4 1.8 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.6 GAP85659.1 - 0.034 14.4 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAP85659.1 - 0.042 14.4 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 GAP85659.1 - 0.088 12.9 0.2 0.23 11.5 0.2 1.8 1 1 0 1 1 1 0 Dynamin family AAA_7 PF12775.7 GAP85659.1 - 0.089 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 GAP85659.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 GAP85659.1 - 0.14 11.2 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) NTPase_1 PF03266.15 GAP85659.1 - 0.32 10.9 1.4 0.51 10.2 0.2 2.0 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 GAP85660.1 - 7.9e-12 45.7 0.0 6.8e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 GAP85660.1 - 7.6e-11 42.1 0.1 1.7e-06 27.8 0.0 2.6 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 GAP85660.1 - 1.5e-08 34.4 0.0 3.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 GAP85660.1 - 5.7e-06 25.9 0.0 9.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 GAP85660.1 - 0.0013 18.5 0.0 0.0037 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAP85660.1 - 0.0095 16.2 0.1 0.34 11.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain Cas_Cas4 PF01930.17 GAP85660.1 - 0.017 15.3 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF83 AAA_12 PF13087.6 GAP85660.1 - 0.018 14.7 0.0 0.049 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 GAP85660.1 - 0.023 14.4 0.0 4.3 7.0 0.0 3.3 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 GAP85660.1 - 0.035 13.9 0.0 0.088 12.6 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 GAP85660.1 - 0.053 13.9 0.0 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.9 GAP85660.1 - 0.15 11.3 0.0 1.8 7.7 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Glyco_hydro_64 PF16483.5 GAP85661.1 - 1.1e-82 278.3 0.0 1.3e-82 278.0 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase HET PF06985.11 GAP85662.1 - 1.9e-34 119.2 0.1 3.3e-34 118.3 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.26 GAP85662.1 - 0.00031 20.7 0.3 0.0031 17.6 0.2 2.6 2 0 0 2 2 2 1 WW domain Amidase PF01425.21 GAP85663.1 - 1.9e-33 116.1 0.1 3e-33 115.5 0.1 1.2 1 0 0 1 1 1 1 Amidase SLAC1 PF03595.17 GAP85664.1 - 9.7e-80 268.2 47.7 1.1e-79 268.0 47.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PAPS_reduct PF01507.19 GAP85665.1 - 4.1e-40 137.7 0.0 6.1e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Asp_Glu_race PF01177.22 GAP85666.1 - 4.9e-55 186.8 0.0 5.5e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Peripla_BP_1 PF00532.21 GAP85666.1 - 0.076 12.4 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family AP_endonuc_2 PF01261.24 GAP85666.1 - 0.08 12.4 0.0 12 5.3 0.0 2.2 1 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Aminotran_5 PF00266.19 GAP85667.1 - 2.1e-31 109.2 0.0 3.2e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAP85667.1 - 0.00054 19.4 0.1 0.0023 17.3 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 GAP85667.1 - 0.0059 15.8 0.1 0.019 14.2 0.0 1.8 3 0 0 3 3 3 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAP85667.1 - 0.007 14.9 0.0 0.012 14.2 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HTH_16 PF12645.7 GAP85667.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain NatB_MDM20 PF09797.9 GAP85667.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Frigida PF07899.11 GAP85667.1 - 0.21 10.8 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Frigida-like protein Pyr_redox_2 PF07992.14 GAP85668.1 - 4e-23 82.1 0.0 7.7e-23 81.1 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP85668.1 - 5.6e-06 26.4 0.8 0.0066 16.5 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 GAP85668.1 - 9.7e-06 25.0 0.2 0.064 12.5 0.0 2.7 3 0 0 3 3 3 2 Thi4 family Pyr_redox_3 PF13738.6 GAP85668.1 - 1.1e-05 24.9 0.0 0.061 12.6 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP85668.1 - 0.00012 21.4 0.0 0.0044 16.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 GAP85668.1 - 0.00014 21.1 0.3 0.046 12.8 0.0 2.3 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 GAP85668.1 - 0.00021 20.5 0.3 0.0067 15.6 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 GAP85668.1 - 0.00046 19.3 0.3 0.072 12.1 0.5 2.2 1 1 1 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 GAP85668.1 - 0.0012 17.6 0.2 0.0029 16.4 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 GAP85668.1 - 0.004 17.4 0.3 0.008 16.4 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP85668.1 - 0.0062 16.2 0.2 0.14 11.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAP85668.1 - 0.023 14.1 0.7 0.023 14.1 0.7 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAP85668.1 - 0.025 13.8 0.1 0.057 12.7 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Aminotran_1_2 PF00155.21 GAP85670.1 - 9.9e-19 67.7 0.0 1.6e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 GAP85671.1 - 1.8e-46 158.7 43.1 1.8e-46 158.7 43.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP85671.1 - 1.3e-17 63.9 26.3 3.3e-17 62.5 11.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 GAP85671.1 - 7.3e-07 28.0 17.4 9.8e-07 27.6 17.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 GAP85672.1 - 1.4e-70 238.4 0.0 1.8e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF983 PF06170.12 GAP85673.1 - 0.093 13.1 1.4 0.12 12.8 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Ank_2 PF12796.7 GAP85674.1 - 1.4e-46 157.0 1.1 6.8e-11 42.6 0.1 7.6 5 2 3 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP85674.1 - 1.3e-37 127.7 9.5 4.9e-09 36.5 0.0 11.4 7 3 4 12 12 12 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP85674.1 - 4.6e-26 90.5 10.3 5.3e-08 33.0 0.2 8.7 7 2 2 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP85674.1 - 2.7e-24 82.6 14.0 0.036 14.6 0.0 13.3 14 1 0 14 14 14 6 Ankyrin repeat Ank PF00023.30 GAP85674.1 - 2.5e-22 78.3 22.4 0.0057 17.1 0.2 11.3 11 1 0 11 11 11 7 Ankyrin repeat Pkinase PF00069.25 GAP85675.1 - 1e-50 172.6 0.0 3.9e-35 121.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP85675.1 - 6.4e-23 81.4 0.1 5.3e-20 71.8 0.1 3.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP85675.1 - 2.2e-05 23.9 0.0 5.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAP85675.1 - 0.00012 22.0 0.1 0.0046 16.9 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAP85675.1 - 0.02 13.7 0.0 0.053 12.3 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase SRP19 PF01922.17 GAP85676.1 - 6e-29 100.8 0.0 9.9e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Pex14_N PF04695.13 GAP85676.1 - 0.15 12.7 8.0 0.25 12.0 8.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PP31 PF05311.11 GAP85676.1 - 0.43 10.0 1.4 0.56 9.7 1.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Suf PF05843.14 GAP85676.1 - 0.49 10.3 4.8 0.7 9.8 4.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 GAP85676.1 - 6.7 6.2 14.3 9.3 5.8 14.3 1.1 1 0 0 1 1 1 0 Spt20 family Dynactin PF12455.8 GAP85677.1 - 1.4e-104 349.4 12.4 1.4e-104 349.4 12.4 4.1 6 0 0 6 6 6 1 Dynein associated protein CAP_GLY PF01302.25 GAP85677.1 - 3.4e-22 78.2 0.3 5.9e-22 77.5 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain F_actin_bind PF08919.10 GAP85677.1 - 0.019 15.0 2.4 1.2 9.3 0.7 3.7 2 0 0 2 2 2 0 F-actin binding MHC_II_beta PF00969.19 GAP85677.1 - 0.63 10.2 2.1 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain p450 PF00067.22 GAP85678.1 - 1e-62 212.5 0.0 9.1e-42 143.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Methyltransf_2 PF00891.18 GAP85678.1 - 1.2e-27 96.6 0.0 3.2e-27 95.2 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain GST_N_3 PF13417.6 GAP85678.1 - 1.9e-05 25.0 0.0 5.8e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAP85678.1 - 4.1e-05 23.8 0.1 0.00024 21.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Dimerisation2 PF16864.5 GAP85678.1 - 0.00018 21.4 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain GST_N PF02798.20 GAP85678.1 - 0.00023 21.4 0.1 0.0009 19.5 0.1 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP85678.1 - 0.00056 20.1 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP85678.1 - 0.0049 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MBOAT_2 PF13813.6 GAP85679.1 - 8.3e-17 61.2 3.6 2.2e-16 59.9 3.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Pyr_redox_2 PF07992.14 GAP85679.1 - 2.1e-09 37.1 0.0 2.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP85679.1 - 0.013 14.2 0.0 3.1 6.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 GAP85679.1 - 0.015 15.5 0.1 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAP85679.1 - 0.038 13.1 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 GAP85679.1 - 0.049 12.9 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP85679.1 - 0.077 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAP85679.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAP85679.1 - 0.42 9.9 1.3 2 7.7 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HMG_box PF00505.19 GAP85680.1 - 3.8e-20 72.1 0.8 6.8e-20 71.3 0.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAP85680.1 - 3.4e-06 27.5 0.5 7.9e-06 26.4 0.5 1.6 1 0 0 1 1 1 1 HMG-box domain SUIM_assoc PF16619.5 GAP85680.1 - 1.9 8.6 10.2 6.9 6.8 10.2 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GAP85680.1 - 5.7 6.5 11.7 0.41 10.2 6.7 1.6 2 0 0 2 2 2 0 Spt20 family TIP49 PF06068.13 GAP85681.1 - 1e-165 551.1 0.1 1.3e-165 550.8 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GAP85681.1 - 9.4e-25 86.5 0.7 2e-24 85.5 0.7 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 GAP85681.1 - 7.4e-11 42.6 0.2 1.6e-06 28.6 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAP85681.1 - 7.8e-09 35.5 0.1 1.9e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAP85681.1 - 3.2e-05 24.2 0.2 0.32 11.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAP85681.1 - 9.2e-05 22.9 0.1 0.00053 20.4 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 GAP85681.1 - 0.00013 22.2 0.2 0.00033 20.9 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAP85681.1 - 0.0019 18.5 1.9 0.18 12.1 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAP85681.1 - 0.0024 17.9 0.2 0.049 13.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAP85681.1 - 0.0036 17.9 0.1 0.014 15.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 GAP85681.1 - 0.0071 15.9 0.2 0.04 13.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAP85681.1 - 0.014 14.8 0.1 0.28 10.5 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 GAP85681.1 - 0.02 14.1 0.2 0.039 13.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 GAP85681.1 - 0.024 14.4 0.1 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 GAP85681.1 - 0.027 14.2 0.1 2.1 8.0 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.6 GAP85681.1 - 0.046 13.4 0.2 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 GAP85681.1 - 0.075 12.1 0.2 0.27 10.2 0.1 1.9 1 1 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 GAP85681.1 - 0.11 11.7 0.3 0.39 10.0 0.1 1.9 3 0 0 3 3 3 0 Zeta toxin AAA_7 PF12775.7 GAP85681.1 - 0.12 11.9 0.1 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region EamA PF00892.20 GAP85682.1 - 6e-19 68.6 26.1 1.9e-12 47.5 2.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family TFIID-18kDa PF02269.16 GAP85683.1 - 5e-21 74.5 0.1 1.1e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 GAP85683.1 - 0.026 14.9 0.0 0.081 13.3 0.0 1.8 1 0 0 1 1 1 0 CENP-S protein CENP-T_C PF15511.6 GAP85683.1 - 0.033 14.3 0.2 0.12 12.5 0.3 2.0 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 GAP85683.1 - 0.043 13.8 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TAF PF02969.17 GAP85683.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF1242 PF06842.12 GAP85684.1 - 1.5e-18 66.3 0.7 2e-18 65.8 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Tcp11 PF05794.13 GAP85685.1 - 3e-106 356.2 0.1 5.5e-106 355.3 0.1 1.4 1 1 0 1 1 1 1 T-complex protein 11 RsbRD_N PF14361.6 GAP85685.1 - 0.0058 17.3 0.2 16 6.2 0.0 3.6 4 0 0 4 4 4 2 RsbT co-antagonist protein rsbRD N-terminal domain Exo_endo_phos PF03372.23 GAP85686.1 - 3.8e-07 29.9 0.0 1.3e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Uds1 PF15456.6 GAP85687.1 - 8.6e-40 135.9 5.5 8.6e-40 135.9 5.5 7.3 4 3 4 8 8 8 1 Up-regulated During Septation CENP-H PF05837.12 GAP85687.1 - 0.002 18.5 8.4 0.002 18.5 8.4 7.3 5 1 4 9 9 9 2 Centromere protein H (CENP-H) ZapB PF06005.12 GAP85687.1 - 0.012 16.1 10.0 0.012 16.1 10.0 8.6 3 2 3 6 6 6 0 Cell division protein ZapB Rhomboid PF01694.22 GAP85688.1 - 0.00067 19.7 7.6 0.001 19.1 5.7 2.1 1 1 1 2 2 2 1 Rhomboid family DUF1751 PF08551.10 GAP85688.1 - 0.0011 19.5 1.2 0.0022 18.5 1.2 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Transgly_assoc PF04226.13 GAP85688.1 - 0.096 13.0 4.6 19 5.6 0.0 3.4 3 0 0 3 3 3 0 Transglycosylase associated protein Gly-zipper_Omp PF13488.6 GAP85688.1 - 0.13 12.2 0.6 0.38 10.8 0.1 2.0 2 0 0 2 2 2 0 Glycine zipper Prenyltransf PF01255.19 GAP85689.1 - 4.5e-80 268.4 0.0 2.1e-79 266.2 0.0 1.7 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase ING PF12998.7 GAP85690.1 - 1.6e-07 31.8 0.0 0.00035 21.1 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAP85690.1 - 2.5e-06 27.2 7.8 4.3e-06 26.5 7.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 GAP85690.1 - 0.29 11.4 1.3 0.73 10.1 1.3 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 GAP85690.1 - 0.5 10.0 2.2 0.93 9.1 2.2 1.4 1 0 0 1 1 1 0 PHD-finger FSA_C PF10479.9 GAP85690.1 - 0.58 8.2 6.1 0.31 9.1 3.4 1.9 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus LRR_6 PF13516.6 GAP85691.1 - 0.00013 21.7 3.7 0.13 12.4 0.1 4.7 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 GAP85691.1 - 0.058 13.8 5.1 0.4 11.2 0.1 4.4 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) AF-4 PF05110.13 GAP85691.1 - 0.18 9.9 1.4 0.24 9.4 1.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LRR_8 PF13855.6 GAP85691.1 - 0.45 10.3 3.1 4.2 7.2 0.0 3.5 4 0 0 4 4 4 0 Leucine rich repeat TauD PF02668.16 GAP85692.1 - 2e-37 129.4 2.2 3.4e-37 128.7 2.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.18 GAP85693.1 - 3.7e-07 30.1 13.2 6.3e-07 29.4 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP85693.1 - 0.014 14.4 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2368 PF10166.9 GAP85693.1 - 0.021 14.4 0.2 0.042 13.5 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) OMPdecase PF00215.24 GAP85694.1 - 1e-95 319.6 0.0 1.2e-95 319.4 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family CDP-OH_P_transf PF01066.21 GAP85695.1 - 2.9e-13 50.4 0.6 2.9e-13 50.4 0.6 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase AA_permease_2 PF13520.6 GAP85697.1 - 2e-48 165.3 47.0 2.4e-48 165.0 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP85697.1 - 1e-25 90.3 36.0 1e-25 90.3 36.0 2.0 1 1 1 2 2 2 1 Amino acid permease BRI3BP PF14965.6 GAP85698.1 - 0.04 13.4 0.5 0.04 13.4 0.5 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Peptidase_S10 PF00450.22 GAP85700.1 - 7.8e-74 249.6 0.0 4.3e-73 247.1 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Bd3614-deam PF14439.6 GAP85700.1 - 0.74 9.9 2.7 0.65 10.1 0.7 1.8 2 0 0 2 2 2 0 Bd3614-like deaminase DUF3632 PF12311.8 GAP85702.1 - 4.6e-34 118.4 1.5 9e-34 117.4 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ank_5 PF13857.6 GAP85703.1 - 1.5e-10 41.1 0.4 8.4e-08 32.3 0.2 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP85703.1 - 3e-10 40.5 0.0 3.6e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP85703.1 - 7.8e-08 32.7 1.2 0.0011 19.5 0.0 4.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 GAP85703.1 - 4.8e-07 29.9 0.0 0.00029 21.2 0.3 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 GAP85703.1 - 1.9e-06 27.7 0.0 7.9e-05 22.8 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat DGF-1_C PF11040.8 GAP85704.1 - 0.32 11.0 4.2 0.28 11.2 3.0 1.5 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Frataxin_Cyay PF01491.16 GAP85705.1 - 7.4e-38 128.9 0.1 9.3e-38 128.6 0.1 1.1 1 0 0 1 1 1 1 Frataxin-like domain Gp_dh_C PF02800.20 GAP85706.1 - 2.8e-72 241.5 0.0 3.8e-72 241.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAP85706.1 - 3.6e-39 133.2 0.0 8e-39 132.1 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 GAP85706.1 - 0.0054 16.9 0.7 0.03 14.5 0.2 2.5 2 1 1 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 GAP85706.1 - 0.058 12.7 0.0 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TIP49 PF06068.13 GAP85707.1 - 4.5e-154 512.9 1.6 5.8e-154 512.5 1.6 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 GAP85707.1 - 1.4e-21 76.4 0.3 7.2e-21 74.1 0.2 2.3 2 0 0 2 2 2 1 TIP49 AAA-lid domain RuvB_N PF05496.12 GAP85707.1 - 4.5e-09 36.2 0.5 6.3e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 GAP85707.1 - 1.5e-08 35.1 0.4 5.4e-05 23.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 GAP85707.1 - 1.2e-06 28.1 0.9 2.4e-06 27.1 0.9 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 GAP85707.1 - 2.9e-06 27.8 1.1 1.7e-05 25.3 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 GAP85707.1 - 0.00031 20.2 0.5 0.0061 16.0 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 GAP85707.1 - 0.0027 18.0 0.1 0.28 11.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 GAP85707.1 - 0.0052 17.1 3.0 0.21 11.9 3.0 2.7 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAP85707.1 - 0.0062 16.3 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_11 PF13086.6 GAP85707.1 - 0.025 14.4 0.6 0.23 11.2 0.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAP85707.1 - 0.053 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAP85707.1 - 0.056 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAP85707.1 - 0.075 12.5 0.2 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 GAP85707.1 - 0.1 12.6 0.1 3.5 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HALZ PF02183.18 GAP85708.1 - 0.019 15.2 5.3 0.027 14.7 0.8 3.4 3 1 0 3 3 2 0 Homeobox associated leucine zipper DUF1664 PF07889.12 GAP85708.1 - 0.02 14.9 26.1 0.25 11.4 0.5 5.7 2 1 3 6 6 6 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GAP85708.1 - 0.025 14.6 27.2 0.54 10.3 1.6 4.0 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CagZ PF09053.10 GAP85708.1 - 0.079 12.6 3.3 0.18 11.4 3.3 1.6 1 0 0 1 1 1 0 CagZ Phage_Gp19 PF09355.10 GAP85708.1 - 0.083 13.3 1.0 0.53 10.7 0.4 2.5 2 0 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 CALCOCO1 PF07888.11 GAP85708.1 - 0.1 11.4 25.0 0.68 8.7 16.7 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like CLZ PF16526.5 GAP85708.1 - 1.5 9.2 25.4 0.4 11.1 0.4 6.8 4 2 3 7 7 7 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MLD PF11647.8 GAP85708.1 - 2 8.8 5.2 2 8.7 0.3 3.2 3 0 0 3 3 3 0 Membrane Localization Domain NPV_P10 PF05531.12 GAP85708.1 - 2 8.9 23.4 2.2 8.8 1.8 6.5 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 GAP85708.1 - 3.6 6.4 35.8 0.45 9.3 0.9 3.8 1 1 3 4 4 4 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.19 GAP85708.1 - 3.9 5.2 33.4 0.83 7.4 28.9 1.9 1 1 1 2 2 2 0 Myosin tail PTH2 PF01981.16 GAP85709.1 - 6.9e-42 142.4 0.3 6.1e-37 126.5 0.1 2.2 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 DUF3438 PF11920.8 GAP85709.1 - 0.11 11.7 2.1 0.61 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3438) GYF PF02213.16 GAP85711.1 - 4.7e-11 42.2 3.2 1.1e-10 41.0 3.2 1.6 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.14 GAP85712.1 - 5.3e-68 227.9 0.0 6.9e-68 227.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 FXMRP1_C_core PF12235.8 GAP85714.1 - 0.87 10.2 4.8 1.6 9.3 4.8 1.6 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal DUF908 PF06012.12 GAP85714.1 - 4.7 6.5 5.2 5.4 6.3 5.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) HET PF06985.11 GAP85716.1 - 2.5e-10 40.9 4.1 1.3e-06 28.8 0.2 3.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Het-C PF07217.11 GAP85717.1 - 3.1e-148 494.8 0.0 3.9e-148 494.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Anophelin PF10731.9 GAP85717.1 - 0.026 14.4 2.6 1.8 8.5 0.4 2.7 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Zn_dep_PLPC PF00882.18 GAP85717.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc dependent phospholipase C Uma2 PF05685.12 GAP85720.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative restriction endonuclease RXT2_N PF08595.11 GAP85720.1 - 0.17 11.9 3.2 0.11 12.6 0.6 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal HET PF06985.11 GAP85721.1 - 0.0017 18.8 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phage_lysozyme PF00959.19 GAP85722.1 - 3.3e-12 46.8 0.0 4.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme DUF2530 PF10745.9 GAP85723.1 - 0.2 11.9 2.0 0.68 10.2 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) Cu_amine_oxid PF01179.20 GAP85724.1 - 4e-155 516.7 0.0 4.9e-155 516.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 GAP85724.1 - 1.4e-09 38.1 0.0 2.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 GAP85724.1 - 3.1e-06 27.5 0.0 1.4e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain adh_short_C2 PF13561.6 GAP85725.1 - 1.4e-52 178.6 2.3 1.6e-52 178.4 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP85725.1 - 5.6e-48 163.0 3.9 6.8e-48 162.7 3.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP85725.1 - 8.6e-19 68.1 2.1 1.2e-18 67.7 2.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP85725.1 - 1.6e-05 24.5 1.0 9.4e-05 22.0 1.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAP85725.1 - 0.00029 20.2 0.5 0.00052 19.4 0.5 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_trans_2 PF11951.8 GAP85726.1 - 2.6e-52 177.9 1.2 3.1e-52 177.7 1.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.6 GAP85727.1 - 4.2e-55 187.3 46.5 5.2e-55 187.0 46.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP85727.1 - 3.6e-21 75.3 37.2 5.4e-21 74.7 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_3 PF07859.13 GAP85728.1 - 1.3e-45 155.9 0.0 1.6e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAP85728.1 - 1.1e-06 27.8 0.0 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Amino_oxidase PF01593.24 GAP85729.1 - 4e-49 168.1 0.0 4.9e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAP85729.1 - 2.9e-13 49.9 0.4 1.7e-12 47.3 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP85729.1 - 9.8e-13 48.4 0.7 4e-12 46.4 0.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAP85729.1 - 1.5e-06 27.8 0.1 2.9e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP85729.1 - 1.5e-05 24.3 2.0 3e-05 23.3 2.0 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAP85729.1 - 5.5e-05 22.6 0.2 0.0006 19.2 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP85729.1 - 0.00015 21.1 0.1 0.00075 18.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP85729.1 - 0.0004 19.2 0.1 0.002 16.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 GAP85729.1 - 0.001 18.4 0.3 0.002 17.4 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 GAP85729.1 - 0.0014 19.1 0.4 0.012 16.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP85729.1 - 0.0026 16.9 0.0 0.006 15.7 0.0 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAP85729.1 - 0.041 12.9 0.1 0.14 11.2 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Autoind_bind PF03472.15 GAP85729.1 - 0.073 12.5 0.0 4 6.9 0.0 2.5 2 0 0 2 2 2 0 Autoinducer binding domain Mac PF12464.8 GAP85730.1 - 4e-13 49.4 0.1 8.2e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 GAP85730.1 - 8.7e-11 41.4 4.4 1.1e-07 31.5 0.6 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 GAP85730.1 - 6.5e-09 35.2 5.0 1.3e-06 27.9 1.1 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) CDC37_N PF03234.14 GAP85732.1 - 1.6e-29 103.5 0.0 5.5e-29 101.7 0.0 2.0 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_C PF08564.10 GAP85732.1 - 8.8e-25 86.7 0.1 2.3e-24 85.4 0.1 1.7 1 0 0 1 1 1 1 Cdc37 C terminal domain CDC37_M PF08565.11 GAP85732.1 - 5.8e-19 68.2 0.0 1.2e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain ProSAAS PF07259.12 GAP85732.1 - 0.015 15.3 0.2 0.035 14.1 0.2 1.6 1 0 0 1 1 1 0 ProSAAS precursor YfbU PF03887.14 GAP85732.1 - 0.055 13.5 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 YfbU domain ScsC_N PF18312.1 GAP85732.1 - 0.25 11.2 0.0 0.25 11.2 0.0 2.5 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain HET PF06985.11 GAP85733.1 - 3.7e-24 85.7 0.2 2.1e-23 83.3 0.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_33 PF13671.6 GAP85734.1 - 2.8e-07 30.8 0.0 4.1e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAP85734.1 - 2.4e-05 24.9 0.0 6.9e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAP85734.1 - 0.0044 16.3 0.0 0.022 14.0 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 GAP85734.1 - 0.0055 17.0 0.0 0.0058 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 GAP85734.1 - 0.013 15.9 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAP85734.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAP85734.1 - 0.17 12.2 0.0 0.18 12.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain Imm58 PF15581.6 GAP85735.1 - 0.0024 17.9 0.1 0.004 17.2 0.1 1.5 1 1 0 1 1 1 1 Immunity protein 58 FAA_hydrolase PF01557.18 GAP85736.1 - 6e-32 111.1 0.0 2.6e-31 109.0 0.0 1.7 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RRM_1 PF00076.22 GAP85737.1 - 2.4e-43 145.8 0.0 1e-15 57.3 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAP85737.1 - 1.1e-34 118.1 0.0 1.8e-27 95.0 0.0 3.9 4 0 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GAP85737.1 - 3.4e-10 39.7 0.0 0.00074 19.5 0.0 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAP85737.1 - 0.0032 17.5 0.0 0.94 9.6 0.0 3.8 3 0 0 3 3 3 1 RNA recognition motif SUIM_assoc PF16619.5 GAP85737.1 - 0.0089 16.1 6.4 0.046 13.8 6.4 2.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 IHABP4_N PF16174.5 GAP85737.1 - 1.3 9.7 22.2 2.8 8.5 8.8 2.5 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Hep_59 PF07052.11 GAP85737.1 - 2.7 8.8 12.8 1.1 10.0 1.7 3.8 3 1 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 PHM7_cyt PF14703.6 GAP85737.1 - 5.4 7.2 12.7 5.5 7.2 0.0 4.7 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter HA2 PF04408.23 GAP85738.1 - 2.7e-15 56.6 2.8 5.7e-15 55.5 0.0 2.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAP85738.1 - 1.3e-14 54.5 0.0 4.1e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAP85738.1 - 5.6e-11 42.5 0.0 1.3e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 GAP85738.1 - 2e-07 31.3 0.0 4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 GAP85738.1 - 5.2e-07 30.0 0.2 5.2e-07 30.0 0.2 3.0 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 GAP85738.1 - 0.036 14.0 0.4 0.15 12.0 0.4 2.0 1 1 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 GAP85738.1 - 0.052 14.1 0.2 0.26 11.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 GAP85738.1 - 0.061 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 KaiC VRR_NUC PF08774.11 GAP85738.1 - 0.15 12.1 1.8 54 3.9 0.1 4.1 4 0 0 4 4 4 0 VRR-NUC domain AAA_23 PF13476.6 GAP85738.1 - 8.2 6.9 0.0 8.2 6.9 0.0 3.9 3 1 0 3 3 3 0 AAA domain Gcn1_N PF12074.8 GAP85739.1 - 3e-118 395.2 0.3 2.3e-117 392.3 0.1 2.9 2 0 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 GAP85739.1 - 8.4e-31 103.4 37.9 0.61 10.5 0.0 23.8 27 0 0 27 27 23 8 HEAT repeat HEAT_EZ PF13513.6 GAP85739.1 - 2e-25 88.8 55.9 2.8e-05 24.5 0.0 21.2 20 6 7 27 27 23 6 HEAT-like repeat HEAT_2 PF13646.6 GAP85739.1 - 9.4e-24 83.6 46.1 3.8e-05 24.0 0.1 15.9 12 5 7 20 20 19 9 HEAT repeats Cnd1 PF12717.7 GAP85739.1 - 2.2e-15 57.1 6.6 2.4 8.2 0.2 11.3 9 3 0 11 11 11 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GAP85739.1 - 4.9e-14 52.7 0.0 1.1 9.9 0.0 9.5 7 1 1 8 8 8 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 GAP85739.1 - 5.7e-10 38.4 4.4 0.011 14.3 1.5 7.0 7 2 2 9 9 9 3 Adaptin N terminal region ParcG PF10274.9 GAP85739.1 - 1e-09 38.8 1.5 0.0012 19.1 0.0 5.7 5 0 0 5 5 5 2 Parkin co-regulated protein UME PF08064.13 GAP85739.1 - 3.8e-08 33.2 0.9 2 8.4 0.0 7.3 6 1 1 7 7 6 1 UME (NUC010) domain CLASP_N PF12348.8 GAP85739.1 - 8.1e-08 32.1 0.0 0.38 10.3 0.0 6.0 5 1 1 6 6 6 2 CLASP N terminal MMS19_C PF12460.8 GAP85739.1 - 2.3e-06 27.0 16.5 0.00055 19.2 0.3 7.3 6 2 3 9 9 9 2 RNAPII transcription regulator C-terminal TIP120 PF08623.10 GAP85739.1 - 7.3e-06 25.9 0.1 0.022 14.5 0.0 6.1 6 2 1 7 7 4 1 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 GAP85739.1 - 2.7e-05 24.1 0.1 0.83 9.5 0.0 5.6 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) DUF937 PF06078.11 GAP85739.1 - 0.00018 22.1 1.3 38 4.9 0.0 6.6 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF937) Tti2 PF10521.9 GAP85739.1 - 0.00097 18.7 8.2 2 7.9 0.0 6.6 7 2 1 8 8 8 2 Tti2 family TAF6_C PF07571.13 GAP85739.1 - 0.0011 19.3 2.0 2.1 8.7 0.0 6.8 7 1 2 9 9 6 1 TAF6 C-terminal HEAT repeat domain Ipi1_N PF12333.8 GAP85739.1 - 0.0012 19.4 0.6 0.28 11.8 0.0 4.1 4 0 0 4 4 3 1 Rix1 complex component involved in 60S ribosome maturation TFCD_C PF12612.8 GAP85739.1 - 0.0083 16.0 2.8 0.097 12.5 0.0 4.3 5 0 0 5 5 5 1 Tubulin folding cofactor D C terminal Pes-10 PF07149.11 GAP85739.1 - 0.018 14.1 0.1 0.034 13.2 0.1 1.4 1 0 0 1 1 1 0 Pes-10 FANCI_S2 PF14676.6 GAP85739.1 - 0.039 14.3 1.0 2.4 8.4 0.1 4.4 5 0 0 5 5 5 0 FANCI solenoid 2 DRIM PF07539.12 GAP85739.1 - 0.046 12.0 15.3 0.35 9.1 0.4 5.2 5 2 1 6 6 6 0 Down-regulated in metastasis Dopey_N PF04118.14 GAP85739.1 - 0.083 12.0 2.2 25 3.9 0.0 4.7 5 2 1 6 6 6 0 Dopey, N-terminal RasGEF_N_2 PF14663.6 GAP85739.1 - 0.083 13.3 0.0 2.1 8.8 0.0 3.6 3 0 0 3 3 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain U3snoRNP10 PF12397.8 GAP85739.1 - 0.096 13.0 14.4 13 6.2 0.0 7.2 6 1 0 6 6 6 0 U3 small nucleolar RNA-associated protein 10 Arm PF00514.23 GAP85739.1 - 0.24 11.5 11.9 21 5.4 0.1 8.2 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 GAP85739.1 - 0.28 12.0 15.3 51 5.0 0.2 8.4 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat RIX1 PF08167.12 GAP85739.1 - 0.3 10.8 7.1 0.21 11.3 0.8 4.1 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Ribosomal_L19e PF01280.20 GAP85740.1 - 1.9e-61 206.4 7.5 1.9e-61 206.4 7.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e TRAP-gamma PF07074.12 GAP85740.1 - 0.079 12.5 5.3 0.13 11.9 5.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) SHMT PF00464.19 GAP85741.1 - 6.3e-196 650.7 0.0 7.4e-196 650.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Hydrolase_6 PF13344.6 GAP85742.1 - 7.6e-24 83.7 0.0 1.3e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP85742.1 - 2.4e-14 53.1 0.0 1.6e-13 50.5 0.0 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 GAP85742.1 - 0.061 13.6 0.0 21 5.3 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Co_AT_N PF12557.8 GAP85742.1 - 2.9 7.9 5.2 5.3 7.1 5.2 1.4 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal adh_short_C2 PF13561.6 GAP85743.1 - 1.3e-52 178.7 0.3 1.6e-52 178.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP85743.1 - 5.3e-41 140.2 0.1 6.2e-41 140.0 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP85743.1 - 7.8e-10 38.9 1.4 1.1e-09 38.4 1.4 1.2 1 0 0 1 1 1 1 KR domain MR_MLE_C PF13378.6 GAP85744.1 - 1.8e-42 145.4 0.0 2.8e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAP85744.1 - 2.3e-10 40.7 0.0 4.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.15 GAP85744.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.4 2 0 0 2 2 2 0 Beta-galactosidase Fungal_trans PF04082.18 GAP85745.1 - 1.4e-23 83.2 0.6 2.1e-23 82.7 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85745.1 - 1.1e-08 35.0 13.0 1.8e-08 34.3 13.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CFEM PF05730.11 GAP85747.1 - 1.4e-08 34.7 7.3 3.7e-08 33.3 7.3 1.7 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 GAP85747.1 - 0.02 14.3 1.4 0.078 12.4 1.4 2.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RIFIN PF02009.16 GAP85747.1 - 0.14 12.0 0.3 0.2 11.5 0.3 1.2 1 0 0 1 1 1 0 Rifin Podoplanin PF05808.11 GAP85747.1 - 4 7.5 17.9 9.4 6.3 16.3 2.4 1 1 1 2 2 2 0 Podoplanin Ribosomal_L22 PF00237.19 GAP85748.1 - 1.5e-20 73.3 0.5 3.9e-20 72.0 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Exonuc_VII_L PF02601.15 GAP85748.1 - 0.4 10.2 6.3 0.095 12.3 3.4 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Mitochondr_Som1 PF11093.8 GAP85749.1 - 2.3e-26 91.6 0.0 2.7e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 FAR1 PF03101.15 GAP85751.1 - 7e-10 39.5 0.1 7e-10 39.5 0.1 2.4 2 1 0 2 2 2 1 FAR1 DNA-binding domain Macoilin PF09726.9 GAP85751.1 - 0.082 11.5 16.9 0.12 11.0 16.9 1.2 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 GAP85751.1 - 0.19 11.3 30.5 0.31 10.6 30.5 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apt1 PF10351.9 GAP85751.1 - 0.6 8.9 16.8 0.86 8.4 16.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP1 PF08601.10 GAP85751.1 - 1.8 8.2 34.8 3.7 7.2 34.8 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Utp14 PF04615.13 GAP85751.1 - 2 6.9 22.6 2.9 6.3 22.6 1.1 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 GAP85751.1 - 2.6 5.0 31.9 3.4 4.7 31.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MMR1 PF08505.10 GAP85751.1 - 3.5 7.8 37.1 8 6.7 37.1 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PAT1 PF09770.9 GAP85751.1 - 4.6 5.4 45.3 7 4.8 45.3 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HTH_AsnC-type PF13404.6 GAP85751.1 - 9.5 6.1 9.4 0.22 11.4 0.5 2.8 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Isochorismatase PF00857.20 GAP85752.1 - 3.4e-26 92.5 0.0 9.9e-26 91.0 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.6 GAP85752.1 - 1.1e-24 87.8 0.0 1.1e-24 87.8 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GST_C_2 PF13410.6 GAP85752.1 - 0.0019 18.2 0.2 0.022 14.8 0.1 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PAT1 PF09770.9 GAP85752.1 - 0.19 10.0 10.8 0.27 9.5 10.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LIM_bind PF01803.16 GAP85752.1 - 1.7 8.1 6.3 3.4 7.1 6.3 1.4 1 0 0 1 1 1 0 LIM-domain binding protein Spt20 PF12090.8 GAP85752.1 - 4.5 6.8 28.0 0.16 11.5 20.4 2.0 2 0 0 2 2 2 0 Spt20 family TAF8_C PF10406.9 GAP85754.1 - 9.6e-13 48.5 2.3 9.6e-13 48.5 2.3 2.2 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 GAP85754.1 - 1.1e-12 47.8 0.0 2.3e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 GAP85754.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone-fold protein WD40 PF00400.32 GAP85755.1 - 3.3e-44 148.0 24.2 7.7e-09 36.1 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP85755.1 - 8.9e-09 35.5 0.7 0.1 12.9 0.0 4.4 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP85755.1 - 2.3e-06 26.6 7.2 0.09 11.4 0.0 4.3 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAP85755.1 - 0.0018 17.3 0.1 8.3 5.3 0.0 4.0 1 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAP85755.1 - 0.0087 16.0 0.3 22 5.1 0.0 4.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 GAP85755.1 - 0.011 15.1 0.0 0.72 9.1 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 GAP85755.1 - 0.023 13.3 0.1 2.9 6.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain mRNA_stabil PF13929.6 GAP85755.1 - 0.17 10.9 0.1 0.58 9.1 0.0 1.7 2 0 0 2 2 2 0 mRNA stabilisation VID27 PF08553.10 GAP85755.1 - 0.2 10.7 0.0 0.9 8.5 0.0 1.9 2 1 0 2 2 2 0 VID27 C-terminal WD40-like domain RNA_pol_Rpb2_6 PF00562.28 GAP85756.1 - 3.7e-124 414.7 0.0 5.6e-124 414.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAP85756.1 - 6.4e-53 179.3 0.0 2.3e-52 177.4 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 GAP85756.1 - 2.3e-46 157.9 0.1 4.5e-46 156.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GAP85756.1 - 2.4e-33 114.4 0.1 6.3e-33 113.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 GAP85756.1 - 1.7e-25 89.0 0.1 4.9e-25 87.5 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 GAP85756.1 - 2.8e-23 82.0 0.1 8.6e-23 80.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 GAP85756.1 - 6.9e-23 81.0 0.2 2.3e-22 79.3 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 SBF2 PF12335.8 GAP85756.1 - 0.21 11.2 0.6 0.47 10.0 0.6 1.5 1 0 0 1 1 1 0 Myotubularin protein DUF2235 PF09994.9 GAP85757.1 - 4.9e-95 318.2 0.2 6.3e-95 317.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 GAP85759.1 - 1.6e-42 145.8 0.0 2.5e-24 85.7 0.0 3.7 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 GAP85759.1 - 0.08 11.7 0.0 0.31 9.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome P450 DUF1958 PF09211.10 GAP85759.1 - 1.3 9.4 6.6 9.1 6.7 1.4 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF1958) E1-E2_ATPase PF00122.20 GAP85760.1 - 5.5e-41 140.1 0.7 1.2e-37 129.2 0.2 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAP85760.1 - 6.9e-36 123.7 5.1 6.9e-36 123.7 5.1 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAP85760.1 - 8.5e-24 85.0 0.7 2.5e-12 47.5 0.7 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAP85760.1 - 5.6e-14 52.0 0.0 1.5e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 GAP85760.1 - 3.6e-11 42.6 0.0 8.3e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAP85760.1 - 0.00033 20.5 0.3 0.0011 18.8 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CcmH PF03918.14 GAP85760.1 - 0.038 13.3 0.2 0.61 9.4 0.2 2.4 2 0 0 2 2 2 0 Cytochrome C biogenesis protein HAD PF12710.7 GAP85760.1 - 0.14 12.5 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Abhydrolase_7 PF12715.7 GAP85760.1 - 0.21 10.8 0.1 0.35 10.0 0.1 1.3 1 0 0 1 1 1 0 Abhydrolase family DUF2231 PF09990.9 GAP85760.1 - 0.22 12.0 2.9 0.15 12.5 0.3 2.0 2 0 0 2 2 1 0 Predicted membrane protein (DUF2231) DUF1772 PF08592.11 GAP85760.1 - 0.51 10.6 3.4 0.39 11.0 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) MgtE PF01769.16 GAP85760.1 - 6.3 7.2 15.9 0.14 12.6 1.6 3.4 4 0 0 4 4 4 0 Divalent cation transporter Abhydrolase_6 PF12697.7 GAP85761.1 - 8.3e-21 75.6 4.9 1.1e-20 75.2 4.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP85761.1 - 5.9e-19 68.7 0.1 1.5e-18 67.4 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP85761.1 - 1.1e-07 31.3 0.0 6.7e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 GAP85761.1 - 0.00088 18.0 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase PF07224.11 GAP85761.1 - 0.073 12.1 0.0 0.29 10.1 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase FAM176 PF14851.6 GAP85762.1 - 0.0009 18.9 0.2 0.0014 18.3 0.2 1.3 1 0 0 1 1 1 1 FAM176 family DUF2457 PF10446.9 GAP85762.1 - 0.0038 16.4 9.9 0.0046 16.2 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) GRA6 PF05084.13 GAP85762.1 - 0.0058 16.6 0.1 0.0058 16.6 0.1 1.3 2 0 0 2 2 2 1 Granule antigen protein (GRA6) DUF4611 PF15387.6 GAP85762.1 - 0.0058 16.8 4.3 0.0086 16.3 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) CobT PF06213.12 GAP85762.1 - 0.04 13.3 4.6 0.047 13.1 4.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 GAP85762.1 - 0.046 12.9 0.2 0.054 12.7 0.2 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.11 GAP85762.1 - 0.051 11.7 2.5 0.061 11.4 2.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Osteopontin PF00865.18 GAP85762.1 - 0.091 12.2 14.2 0.11 12.0 14.2 1.0 1 0 0 1 1 1 0 Osteopontin Polyoma_lg_T_C PF06431.11 GAP85762.1 - 0.14 11.1 1.6 0.18 10.7 1.6 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Sigma70_ner PF04546.13 GAP85762.1 - 0.25 11.2 3.1 0.29 11.0 3.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 GAP85762.1 - 0.56 8.7 4.1 0.63 8.5 4.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 GAP85762.1 - 0.65 9.3 8.3 0.75 9.1 8.3 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GAP85762.1 - 0.69 8.0 8.6 0.8 7.8 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family SMN PF06003.12 GAP85762.1 - 1.2 8.4 9.2 2.1 7.6 9.2 1.4 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) GCIP PF13324.6 GAP85762.1 - 2 8.0 7.2 2.4 7.7 7.2 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 GAP85762.1 - 2.3 7.5 14.0 2.9 7.1 14.0 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GAP85762.1 - 2.8 5.9 14.5 3.1 5.8 14.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 GAP85762.1 - 4.8 5.4 9.6 5.7 5.1 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein IDO PF01231.18 GAP85763.1 - 6.7e-161 535.9 0.0 7.7e-161 535.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.13 GAP85764.1 - 8.2e-36 122.5 0.0 1.4e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 GAP85764.1 - 1.1e-20 73.3 0.0 2e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain DUF1764 PF08576.10 GAP85765.1 - 1.4 9.9 9.2 6.2 7.8 9.3 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Abhydrolase_3 PF07859.13 GAP85766.1 - 1.5e-27 96.9 0.0 1.8e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP85766.1 - 1.2e-13 50.7 0.0 1.7e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF3089 PF11288.8 GAP85766.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3089) Peptidase_S9 PF00326.21 GAP85766.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family CFEM PF05730.11 GAP85767.1 - 2.9e-13 49.7 12.2 4.3e-13 49.1 12.2 1.3 1 0 0 1 1 1 1 CFEM domain DUF3810 PF12725.7 GAP85767.1 - 1.6 8.0 9.1 6.4 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) FixS PF03597.15 GAP85767.1 - 9.2 6.1 9.2 1.2 8.9 3.1 2.6 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF829 PF05705.14 GAP85768.1 - 1.3e-36 126.7 0.0 1.7e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.16 GAP85769.1 - 6.2e-31 107.6 46.7 1.3e-26 93.4 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAP85769.1 - 5.4e-13 48.2 11.1 6.6e-13 47.9 11.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ketoacyl-synt PF00109.26 GAP85770.1 - 2e-70 237.3 0.7 4.1e-70 236.2 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAP85770.1 - 1.8e-50 172.2 0.0 2.7e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAP85770.1 - 4.4e-47 160.7 0.2 7.5e-47 160.0 0.2 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAP85770.1 - 7.2e-34 116.3 0.0 1.9e-33 115.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAP85770.1 - 1.8e-15 57.5 0.0 4.5e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP85770.1 - 1.2e-10 41.9 0.0 4.5e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP85770.1 - 1.2e-10 41.9 0.0 6.2e-10 39.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAP85770.1 - 2.3e-10 40.9 0.0 8.5e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 GAP85770.1 - 2.9e-10 40.2 0.0 6.4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP85770.1 - 5.7e-09 36.0 0.0 5.4e-08 32.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP85770.1 - 0.00032 20.1 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 GAP85770.1 - 0.0005 21.1 0.0 0.0031 18.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 GAP85770.1 - 0.0013 18.2 0.4 0.0029 17.0 0.4 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_PK PF05891.12 GAP85770.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 GAP85770.1 - 0.003 17.3 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase RrnaAD PF00398.20 GAP85770.1 - 0.054 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase KR PF08659.10 GAP85771.1 - 1.3e-64 217.4 0.1 3.5e-64 216.0 0.0 1.8 2 0 0 2 2 2 1 KR domain ADH_zinc_N_2 PF13602.6 GAP85771.1 - 3.3e-17 63.8 0.0 2e-16 61.2 0.0 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAP85771.1 - 7.2e-14 51.9 0.1 4.6e-13 49.3 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAP85771.1 - 3.6e-12 46.1 0.3 8.4e-11 41.7 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.25 GAP85771.1 - 4.2e-10 39.8 0.0 1.1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PALP PF00291.25 GAP85771.1 - 0.0015 18.0 0.1 0.016 14.6 0.0 2.3 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Creatininase PF02633.14 GAP85771.1 - 0.012 15.1 0.1 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 Creatinine amidohydrolase WD40 PF00400.32 GAP85772.1 - 1.9e-36 123.4 18.1 2.7e-11 43.8 0.0 7.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP85772.1 - 5.4e-22 77.9 0.0 3.1e-07 30.6 0.0 5.6 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT_N PF17100.5 GAP85772.1 - 3.8e-21 76.0 0.0 6.3e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ge1_WD40 PF16529.5 GAP85772.1 - 2.5e-07 30.0 0.0 0.57 9.1 0.0 4.8 4 1 1 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 GAP85772.1 - 3e-06 27.2 0.0 6.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Proteasom_PSMB PF10508.9 GAP85772.1 - 0.11 11.0 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit FTA4 PF13093.6 GAP85773.1 - 7.3e-12 45.6 0.1 9.2e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Peptidase_C2 PF00648.21 GAP85774.1 - 5.6e-64 216.0 1.1 2.7e-62 210.5 1.1 2.3 1 1 0 1 1 1 1 Calpain family cysteine protease OAD_gamma PF04277.13 GAP85774.1 - 0.35 11.5 0.0 0.35 11.5 0.0 4.9 3 2 1 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Glyco_hydro_16 PF00722.21 GAP85775.1 - 3.5e-15 55.9 0.1 5.4e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 GAP85775.1 - 0.00077 18.0 1.6 0.23 9.8 0.8 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 GAP85775.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) F-box PF00646.33 GAP85776.1 - 1e-08 34.9 1.4 2.6e-08 33.5 1.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAP85776.1 - 1.3e-07 31.4 1.7 4.8e-07 29.6 1.7 2.1 1 0 0 1 1 1 1 F-box-like ANAPC3 PF12895.7 GAP85776.1 - 0.031 14.5 0.2 0.88 9.8 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAP85776.1 - 0.12 13.0 4.9 33 5.4 1.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAP85776.1 - 0.14 12.0 0.1 4.1 7.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAP85776.1 - 0.25 11.6 1.8 15 6.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAP85776.1 - 1.6 9.7 6.3 7.5 7.7 0.6 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAP85776.1 - 2 8.7 7.5 19 5.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ADIP PF11559.8 GAP85777.1 - 5.9e-42 143.3 7.1 5.9e-42 143.3 7.1 2.2 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 GAP85777.1 - 0.0033 17.0 5.3 0.0033 17.0 5.3 2.2 2 1 0 2 2 2 1 Golgin subfamily A member 5 PS_Dcarbxylase PF02666.15 GAP85778.1 - 8.1e-56 188.7 0.0 1.3e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 GAP85778.1 - 2.5e-39 133.7 0.0 3.5e-18 65.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 GAP85778.1 - 0.0037 16.7 0.6 0.0092 15.5 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GAP85778.1 - 0.012 15.5 0.5 0.1 12.6 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 GAP85778.1 - 0.03 14.8 0.0 0.16 12.4 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 GAP85778.1 - 0.047 13.2 0.0 0.16 11.6 0.0 2.0 1 0 0 1 1 1 0 EF hand Phage-scaffold PF09306.10 GAP85778.1 - 0.066 12.6 1.1 0.13 11.6 1.1 1.4 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein PBP1_TM PF14812.6 GAP85778.1 - 0.94 9.9 7.9 2.9 8.3 7.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HAD PF12710.7 GAP85779.1 - 3.1e-25 89.7 0.4 4.7e-25 89.1 0.1 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 GAP85779.1 - 0.0029 17.0 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.26 GAP85779.1 - 0.063 13.6 0.2 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 GAP85779.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Inv-AAD PF18785.1 GAP85780.1 - 3.1e-48 162.9 0.0 4.2e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 GAP85780.1 - 2.1e-13 50.0 0.0 2.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF3391 PF11871.8 GAP85780.1 - 0.032 14.8 0.3 0.86 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) NACHT PF05729.12 GAP85781.1 - 1e-07 32.1 0.0 2.7e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.7 GAP85781.1 - 8.5e-06 26.5 0.6 3.2e-05 24.6 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family ANAPC4_WD40 PF12894.7 GAP85781.1 - 2.2e-05 24.7 0.0 1.3 9.4 0.0 5.1 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 GAP85781.1 - 9.8e-05 22.8 0.2 0.0056 17.1 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain PGAP1 PF07819.13 GAP85781.1 - 0.00029 20.6 0.0 0.00085 19.1 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAP85781.1 - 0.0012 18.4 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_18 PF13238.6 GAP85781.1 - 0.011 16.3 0.1 0.086 13.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain Hydrolase_4 PF12146.8 GAP85781.1 - 0.043 13.1 0.0 0.089 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AAA_25 PF13481.6 GAP85781.1 - 0.048 13.2 0.1 16 5.0 0.0 3.1 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAP85781.1 - 0.052 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 GAP85781.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 GAP85781.1 - 0.088 13.1 0.0 1 9.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Flu_C_NS1 PF03506.13 GAP85781.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) NTPase_1 PF03266.15 GAP85781.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 GAP85781.1 - 0.11 12.7 0.1 0.72 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAP85781.1 - 0.12 12.6 0.0 0.93 9.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 GAP85781.1 - 0.16 12.4 0.0 0.51 10.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 GAP85781.1 - 0.18 11.1 0.0 0.42 9.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 GAP85781.1 - 2.3 8.1 4.1 0.73 9.6 0.0 2.3 3 0 0 3 3 2 0 P-loop containing region of AAA domain cIII PF08134.11 GAP85783.1 - 0.086 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 cIII protein family MARVEL PF01284.23 GAP85784.1 - 3.4e-07 30.4 9.0 3.4e-07 30.4 9.0 1.8 2 0 0 2 2 2 1 Membrane-associating domain NnrS PF05940.12 GAP85784.1 - 0.0085 15.5 9.0 0.014 14.8 9.0 1.3 1 0 0 1 1 1 1 NnrS protein MASE3 PF17159.4 GAP85784.1 - 0.014 15.1 3.3 0.017 14.7 3.3 1.1 1 0 0 1 1 1 0 Membrane-associated sensor domain DUF1774 PF08611.10 GAP85784.1 - 0.036 14.4 2.4 0.036 14.4 2.4 3.0 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1774) T4SS_CagC PF16943.5 GAP85784.1 - 0.12 12.6 1.8 9.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system DUF4231 PF14015.6 GAP85784.1 - 0.13 12.8 0.8 0.27 11.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) SIS PF01380.22 GAP85785.1 - 3.7e-12 46.2 0.0 8.4e-12 45.1 0.0 1.6 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 GAP85785.1 - 0.024 14.7 0.1 0.12 12.4 0.1 2.0 1 1 1 2 2 2 0 SIS domain DAO PF01266.24 GAP85786.1 - 1.2e-20 74.4 1.4 2.4e-20 73.5 1.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP85786.1 - 0.00056 20.1 0.0 0.0017 18.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP85786.1 - 0.00081 18.7 0.0 0.023 14.0 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP85786.1 - 0.0026 18.3 0.0 0.0047 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP85786.1 - 0.0075 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 GAP85786.1 - 0.0077 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.21 GAP85786.1 - 0.0078 15.6 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 ThiF family GIDA PF01134.22 GAP85786.1 - 0.054 12.6 0.1 0.69 8.9 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 GAP85786.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 GAP85786.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 GAP85786.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA p450 PF00067.22 GAP85787.1 - 2.9e-70 237.3 0.0 3.8e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rhamnogal_lyase PF06045.11 GAP85787.1 - 0.16 11.3 0.0 0.4 10.1 0.0 1.6 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family RRM_1 PF00076.22 GAP85789.1 - 4.1e-17 61.8 0.3 1.4e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAS PF13851.6 GAP85789.1 - 0.0013 18.1 1.1 0.0018 17.7 1.1 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ZapB PF06005.12 GAP85789.1 - 0.0031 17.9 3.4 0.0051 17.2 3.4 1.2 1 0 0 1 1 1 1 Cell division protein ZapB RRM_occluded PF16842.5 GAP85789.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif GPS2_interact PF15784.5 GAP85789.1 - 0.036 14.5 0.6 0.061 13.8 0.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Nup35_RRM_2 PF14605.6 GAP85789.1 - 0.042 13.9 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Spc7 PF08317.11 GAP85789.1 - 0.05 12.5 0.9 0.065 12.1 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GCIP PF13324.6 GAP85789.1 - 0.093 12.3 0.8 0.14 11.8 0.1 1.5 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting DUF2913 PF11140.8 GAP85789.1 - 0.11 12.3 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Spc24 PF08286.11 GAP85789.1 - 0.15 12.3 1.0 0.24 11.7 1.0 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 GRP PF07172.11 GAP85789.1 - 2.1 9.1 19.4 1.2 9.8 15.6 2.1 2 0 0 2 2 2 0 Glycine rich protein family WD40 PF00400.32 GAP85790.1 - 6.7e-24 83.7 14.5 1.6e-07 31.9 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP85790.1 - 3.3e-10 40.1 0.1 0.078 13.3 0.0 4.3 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP85790.1 - 0.057 12.1 0.0 2.9 6.4 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Zn_clus PF00172.18 GAP85793.1 - 3.3e-09 36.7 15.6 5.3e-09 36.1 15.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FIN1 PF17300.2 GAP85793.1 - 0.052 13.0 0.3 0.082 12.4 0.3 1.2 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Snapin_Pallidin PF14712.6 GAP85793.1 - 0.058 13.8 1.0 0.091 13.2 0.1 1.7 2 0 0 2 2 2 0 Snapin/Pallidin ABC_tran_CTD PF16326.5 GAP85793.1 - 0.17 12.2 0.3 15 6.0 0.1 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain HIPIP PF01355.17 GAP85793.1 - 3 8.2 7.8 6.2 7.3 7.8 1.4 1 0 0 1 1 1 0 High potential iron-sulfur protein APG5 PF04106.12 GAP85794.1 - 8.3e-46 156.4 0.0 2.4e-45 154.9 0.0 1.6 1 1 0 1 1 1 1 Autophagy protein Apg5 Ten1 PF12658.7 GAP85797.1 - 6.1e-25 87.5 0.0 8.2e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 GAP85797.1 - 0.00019 21.1 0.0 0.00054 19.7 0.0 1.7 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit Snf7 PF03357.21 GAP85798.1 - 4.4e-33 114.3 21.4 4.4e-33 114.3 21.4 1.9 1 1 1 2 2 2 1 Snf7 DUF3854 PF12965.7 GAP85798.1 - 0.071 13.1 1.0 0.13 12.2 0.2 1.9 2 1 0 3 3 3 0 Domain of unknown function (DUF3854) DUF1216 PF06746.11 GAP85798.1 - 0.14 12.1 11.5 1.1 9.3 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) DUF3138 PF11336.8 GAP85798.1 - 0.82 8.2 11.5 0.28 9.7 7.9 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3138) Allexi_40kDa PF05549.11 GAP85798.1 - 3.8 6.9 10.8 1.2 8.6 6.3 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF963 PF06131.11 GAP85800.1 - 2.7 7.5 13.9 1.4 8.4 0.2 5.0 2 1 1 4 4 4 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF3824 PF12868.7 GAP85801.1 - 1e-07 32.7 49.8 1e-07 32.7 49.8 9.4 5 3 5 10 10 10 4 Domain of unknwon function (DUF3824) Gly-zipper_Omp PF13488.6 GAP85801.1 - 0.0013 18.7 17.6 0.014 15.4 4.8 4.0 4 0 0 4 4 4 2 Glycine zipper Gly-zipper_YMGG PF13441.6 GAP85801.1 - 0.011 15.5 7.1 0.011 15.5 7.1 4.2 4 1 0 4 4 4 0 YMGG-like Gly-zipper DUF3759 PF12585.8 GAP85801.1 - 0.47 10.5 14.9 0.14 12.2 2.1 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3759) TraT PF05818.12 GAP85801.1 - 0.71 9.5 2.2 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein NDUF_B12 PF08122.12 GAP85801.1 - 1.1 9.4 5.5 5.3 7.2 0.0 3.7 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family Spermine_synth PF01564.17 GAP85802.1 - 9.7e-72 240.3 0.0 1.7e-71 239.6 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 GAP85802.1 - 8e-25 86.5 0.1 1.6e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 GAP85802.1 - 3.2e-05 24.5 0.0 7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP85802.1 - 0.0052 17.5 0.1 0.032 15.0 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain DUF43 PF01861.16 GAP85802.1 - 0.0066 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_30 PF05430.11 GAP85802.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 GAP85802.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain VCPO_N PF17897.1 GAP85802.1 - 0.1 12.3 0.4 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Vanadium chloroperoxidase N-terminal domain Methyltransf_24 PF13578.6 GAP85802.1 - 0.12 13.5 0.1 0.44 11.6 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 GAP85802.1 - 0.12 11.6 0.2 0.38 10.0 0.1 1.8 1 1 1 2 2 2 0 O-methyltransferase domain Methyltransf_23 PF13489.6 GAP85802.1 - 0.15 11.9 0.0 0.39 10.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FSA_C PF10479.9 GAP85802.1 - 4.7 5.2 6.6 6.5 4.8 6.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ran_BP1 PF00638.18 GAP85803.1 - 2.4e-12 47.2 0.0 4.6e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain SCP2 PF02036.17 GAP85804.1 - 1.9e-24 86.1 0.3 2.3e-24 85.8 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 GAP85804.1 - 3.7e-06 27.2 0.1 7.5e-06 26.2 0.1 1.5 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 GAP85804.1 - 0.0014 19.0 0.0 0.0018 18.7 0.0 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain Fungal_trans_2 PF11951.8 GAP85805.1 - 1.2e-52 179.0 6.4 1.5e-52 178.7 6.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85805.1 - 2.2e-08 34.1 5.0 3.9e-08 33.3 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.22 GAP85806.1 - 6.9e-46 156.7 0.0 8.7e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AA_permease_2 PF13520.6 GAP85807.1 - 1.6e-53 182.1 48.8 1.9e-53 181.8 48.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP85807.1 - 2.2e-25 89.2 41.5 2.8e-25 88.9 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease SLATT_5 PF18160.1 GAP85807.1 - 0.51 9.6 3.6 0.34 10.2 1.2 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 GCS PF03074.16 GAP85808.1 - 1.8e-173 577.0 0.0 2.2e-173 576.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.27 GAP85809.1 - 4.3e-16 58.2 3.5 6.7e-16 57.6 3.5 1.3 1 0 0 1 1 1 1 GATA zinc finger Periviscerokin PF08259.11 GAP85810.1 - 0.11 12.8 3.8 0.3 11.5 3.8 1.8 1 0 0 1 1 1 0 Periviscerokinin family MFS_1 PF07690.16 GAP85811.1 - 2.3e-06 26.8 39.0 2.8e-05 23.2 31.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MNHE PF01899.16 GAP85811.1 - 0.39 10.5 2.8 2 8.1 2.8 2.2 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit MARVEL PF01284.23 GAP85812.1 - 2.9e-19 69.5 14.4 3.6e-19 69.2 14.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain Collagen PF01391.18 GAP85813.1 - 1.5e-07 31.0 39.0 4.4e-06 26.3 15.3 5.1 4 1 1 5 5 5 2 Collagen triple helix repeat (20 copies) Methyltransf_23 PF13489.6 GAP85814.1 - 2.7e-09 37.1 0.0 4.4e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP85814.1 - 1.4e-05 25.6 0.0 0.00041 20.9 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP85814.1 - 0.00053 20.7 0.0 0.00094 19.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP85814.1 - 0.00065 19.1 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAP85814.1 - 0.0018 19.0 0.0 0.088 13.5 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 GAP85814.1 - 0.1 11.8 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family DnaJ_C PF01556.18 GAP85815.1 - 9e-26 90.7 0.0 1.3e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAP85815.1 - 3.2e-25 88.0 0.8 6.5e-25 87.0 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAP85815.1 - 4.4e-14 52.6 15.1 8.2e-14 51.7 15.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAP85815.1 - 5.9e-05 23.0 6.7 0.041 13.8 0.4 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 GAP85815.1 - 0.0081 16.2 6.6 0.37 10.8 0.9 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Peptidase_MA_2 PF13485.6 GAP85815.1 - 0.24 11.0 0.0 0.39 10.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase MA superfamily TackOD1 PF18551.1 GAP85815.1 - 1.2 8.7 7.4 3 7.5 0.6 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 OB_NTP_bind PF07717.16 GAP85816.1 - 5.7e-22 77.9 0.0 1.5e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GAP85816.1 - 4.1e-19 68.9 0.1 4.1e-19 68.9 0.1 4.1 4 1 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAP85816.1 - 3.1e-15 56.5 0.0 8.9e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAP85816.1 - 1.1e-05 25.2 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAP85816.1 - 2e-05 24.9 0.0 5.6e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAP85816.1 - 0.0013 18.5 1.5 0.0015 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAP85816.1 - 0.005 15.9 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 GAP85816.1 - 0.012 15.3 0.2 0.027 14.1 0.2 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 GAP85816.1 - 0.017 15.4 0.1 0.052 13.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAP85816.1 - 0.036 14.6 0.0 0.16 12.5 0.0 2.1 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.20 GAP85817.1 - 5.8e-108 361.2 0.8 6.9e-108 361.0 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAP85817.1 - 6.2e-13 48.6 1.3 4.7e-08 32.7 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAP85817.1 - 0.00034 20.1 1.6 0.021 14.2 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAP85817.1 - 0.039 14.2 0.6 7.8 6.8 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 GAP85817.1 - 0.054 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 GAP85817.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Glyco_hydro_3 PF00933.21 GAP85818.1 - 1.3e-40 139.7 0.0 2.8e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAP85818.1 - 3.1e-39 135.0 0.0 5.9e-39 134.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 GAP85818.1 - 9.5e-22 76.9 0.1 1.7e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.18 GAP85819.1 - 6.4e-10 38.5 0.0 1.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85819.1 - 5.1e-08 32.9 15.0 1.2e-07 31.7 15.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.19 GAP85820.1 - 6.6e-11 42.8 12.7 0.0011 19.0 0.0 4.2 3 1 1 4 4 4 3 SPX domain GAF_2 PF13185.6 GAP85821.1 - 7.8e-08 32.7 0.0 1.5e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 GAP85821.1 - 0.00048 20.8 0.1 0.0011 19.6 0.0 1.6 2 0 0 2 2 2 1 GAF domain AlaDh_PNT_C PF01262.21 GAP85821.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CN_hydrolase PF00795.22 GAP85822.1 - 9e-53 179.3 0.0 1e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BiPBP_C PF06832.12 GAP85822.1 - 0.037 14.1 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family HET PF06985.11 GAP85823.1 - 4.3e-33 114.7 1.3 8.5e-33 113.8 1.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kelch_6 PF13964.6 GAP85824.1 - 1.5e-06 28.3 0.1 0.053 13.8 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 GAP85824.1 - 3.5e-05 23.7 1.6 0.0015 18.5 0.2 2.9 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.6 GAP85824.1 - 0.00017 21.7 3.7 0.1 12.9 0.1 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAP85824.1 - 0.001 18.6 0.0 0.013 15.1 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 GAP85824.1 - 0.0093 15.9 1.8 30 4.7 0.1 4.1 3 1 0 3 3 3 0 Kelch motif TMEM132D_C PF15706.5 GAP85824.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EphA2_TM PF14575.6 GAP85824.1 - 0.035 15.0 0.0 0.074 13.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 GAP85824.1 - 0.047 13.8 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Podoplanin Shisa PF13908.6 GAP85824.1 - 0.098 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator VSP PF03302.13 GAP85824.1 - 0.24 10.2 1.3 0.35 9.7 1.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DAP10 PF07213.11 GAP85824.1 - 0.5 10.4 2.1 0.37 10.8 0.1 1.8 2 0 0 2 2 2 0 DAP10 membrane protein ArfGap PF01412.18 GAP85826.1 - 7.9e-39 132.4 0.2 1.5e-38 131.5 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pyridoxal_deC PF00282.19 GAP85829.1 - 1.9e-25 89.4 0.0 4.2e-25 88.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 GAP85829.1 - 5.1e-05 22.7 0.0 7.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAP85829.1 - 0.0015 17.8 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase PF00069.25 GAP85830.1 - 1.7e-27 96.5 0.0 2.3e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP85830.1 - 2.9e-14 53.0 0.0 3.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP85830.1 - 9.3e-07 28.0 0.0 1.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase EMP24_GP25L PF01105.24 GAP85831.1 - 4e-53 180.1 0.1 4.5e-53 179.9 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SANT_DAMP1_like PF16282.5 GAP85832.1 - 1.2e-30 105.5 0.4 2.9e-30 104.3 0.4 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 GAP85832.1 - 0.0063 16.4 11.4 0.82 9.5 8.1 3.4 2 1 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) HGD-D PF06050.13 GAP85832.1 - 0.15 11.8 2.6 3.7 7.2 0.9 2.1 2 0 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF1413 PF07205.11 GAP85833.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) Kinesin PF00225.23 GAP85834.1 - 1e-106 356.6 0.0 2.8e-106 355.2 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 GAP85834.1 - 6.9e-47 159.9 0.0 4.4e-46 157.3 0.0 2.3 2 1 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 GAP85834.1 - 8.2e-37 127.1 12.9 3.7e-31 108.7 0.3 3.8 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 GAP85834.1 - 1.3e-21 77.1 0.0 3.9e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 GAP85834.1 - 2.5e-06 27.8 0.7 8.3e-06 26.1 0.7 2.0 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 GAP85834.1 - 9.4e-05 22.7 0.4 0.00063 20.0 0.3 2.5 2 0 0 2 2 2 1 FHA domain PH PF00169.29 GAP85834.1 - 0.073 13.6 0.0 0.79 10.3 0.0 2.6 1 1 0 1 1 1 0 PH domain Peptidase_M1 PF01433.20 GAP85835.1 - 6.8e-43 146.8 0.2 1e-42 146.2 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 GAP85835.1 - 3.5e-30 104.4 0.0 9.1e-30 103.0 0.0 1.7 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 GAP85835.1 - 3e-23 83.0 0.0 6.1e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 GAP85835.1 - 0.48 10.8 3.1 7.1 7.1 1.9 2.8 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Uds1 PF15456.6 GAP85836.1 - 8.9e-32 110.0 8.9 2.1e-31 108.8 8.9 1.7 1 0 0 1 1 1 1 Up-regulated During Septation Stathmin PF00836.19 GAP85836.1 - 0.016 15.2 0.3 0.062 13.3 0.3 2.0 1 0 0 1 1 1 0 Stathmin family Wbp11 PF09429.10 GAP85836.1 - 0.054 13.9 0.6 0.054 13.9 0.6 2.0 2 0 0 2 2 2 0 WW domain binding protein 11 K_channel_TID PF07941.11 GAP85836.1 - 0.064 13.7 1.4 0.17 12.4 1.4 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Spc7 PF08317.11 GAP85836.1 - 0.22 10.4 2.5 0.37 9.6 2.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-RING_UBOX PF13445.6 GAP85837.1 - 0.032 14.2 1.7 0.064 13.3 1.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 GAP85837.1 - 0.043 14.2 7.9 0.18 12.2 7.9 2.0 1 1 0 1 1 1 0 Ring finger domain Trm112p PF03966.16 GAP85837.1 - 0.054 14.1 0.2 0.12 12.9 0.2 1.8 1 0 0 1 1 1 0 Trm112p-like protein DUF2011 PF09428.10 GAP85838.1 - 0.011 16.0 0.0 0.059 13.6 0.0 2.0 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Proteasome PF00227.26 GAP85839.1 - 5.6e-49 166.2 0.0 7.8e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAP85839.1 - 1.6e-12 46.9 0.1 1.6e-12 46.9 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SCP2 PF02036.17 GAP85839.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 SCP-2 sterol transfer family DUF2373 PF10180.9 GAP85840.1 - 3.5e-19 68.4 0.0 7.1e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) FancD2 PF14631.6 GAP85840.1 - 0.7 7.2 3.0 1 6.7 3.0 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease L_HMGIC_fpl PF10242.9 GAP85841.1 - 0.00045 20.5 1.0 0.0012 19.1 1.0 1.8 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DHquinase_I PF01487.15 GAP85842.1 - 1.2e-42 146.8 0.0 1.6e-42 146.3 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.18 GAP85843.1 - 1.9e-24 86.1 0.0 2.8e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85843.1 - 1.6e-05 24.9 15.8 3.3e-05 23.9 15.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 GAP85844.1 - 4.4e-29 101.7 3.3 7.5e-29 101.0 3.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ketoacyl-synt PF00109.26 GAP85848.1 - 8.6e-72 241.7 0.3 2.6e-71 240.2 0.2 1.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAP85848.1 - 3.4e-32 110.9 0.0 6.4e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 GAP85848.1 - 2.4e-23 81.8 0.0 5.4e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain PP-binding PF00550.25 GAP85848.1 - 4.8e-19 68.5 0.9 2.9e-09 37.1 0.2 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 GAP85848.1 - 1.1e-17 64.6 0.0 5.3e-17 62.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.6 GAP85848.1 - 1.1e-15 57.7 0.0 1.7e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP85848.1 - 5.5e-15 55.7 0.0 9.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_23 PF13489.6 GAP85848.1 - 1.7e-10 40.9 0.0 5.9e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP85848.1 - 8.9e-10 39.2 0.0 3.1e-09 37.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP85848.1 - 5.8e-09 36.5 0.0 3e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAP85848.1 - 3.3e-07 30.8 0.0 6.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 GAP85848.1 - 2.4e-06 27.4 0.0 6.7e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 GAP85848.1 - 0.00052 19.5 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 GAP85848.1 - 0.0019 17.6 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 GAP85848.1 - 0.0022 17.2 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FAD_binding_4 PF01565.23 GAP85849.1 - 4.3e-20 71.9 1.9 4.3e-20 71.9 1.9 1.5 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAP85849.1 - 0.0011 19.0 0.7 0.0023 18.0 0.7 1.6 1 0 0 1 1 1 1 Berberine and berberine like Guanylin PF02058.15 GAP85849.1 - 0.011 16.1 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 Guanylin precursor Myelin_PLP PF01275.19 GAP85850.1 - 0.49 10.2 9.3 0.27 11.0 4.2 2.3 1 1 1 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) DUF2207 PF09972.9 GAP85850.1 - 2.9 6.6 5.3 4.5 5.9 5.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Methyltransf_2 PF00891.18 GAP85851.1 - 4.9e-19 68.5 0.0 8.1e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAP85851.1 - 2.3e-06 28.2 0.0 4.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP85851.1 - 0.0025 18.5 0.0 0.0046 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAP85851.1 - 0.026 14.0 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.12 GAP85851.1 - 0.065 13.9 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 GAP85851.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 GAP85851.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 GAP85851.1 - 0.19 11.2 0.1 0.34 10.4 0.1 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain NAD_binding_8 PF13450.6 GAP85852.1 - 4.9e-13 49.1 0.0 5.6e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 GAP85852.1 - 4.8e-12 45.1 0.0 1.9e-11 43.1 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAP85852.1 - 2.7e-11 43.3 0.0 7.2e-10 38.6 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP85852.1 - 8.1e-11 41.7 0.0 1.5e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP85852.1 - 4.4e-06 26.5 0.5 2.9e-05 23.8 0.5 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAP85852.1 - 1.3e-05 24.6 0.2 0.00033 19.9 0.0 2.9 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 GAP85852.1 - 0.00019 20.7 0.1 0.00049 19.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 GAP85852.1 - 0.00049 20.1 0.0 0.24 11.4 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding Mqo PF06039.15 GAP85852.1 - 0.0069 15.0 0.3 0.43 9.1 0.0 2.2 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 GAP85852.1 - 0.054 14.1 0.4 22 5.7 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PD40 PF07676.12 GAP85852.1 - 0.061 13.3 0.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat FAD_binding_3 PF01494.19 GAP85852.1 - 0.086 12.1 0.4 0.15 11.2 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Bac_luciferase PF00296.20 GAP85853.1 - 1.3e-60 205.4 0.0 2e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 GAP85853.1 - 3.6e-27 95.2 33.3 5.1e-27 94.7 33.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Bac_luciferase PF00296.20 GAP85854.1 - 5e-59 200.3 1.2 6.4e-59 199.9 1.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase UNC-93 PF05978.16 GAP85855.1 - 1.5e-06 28.0 3.9 1.5e-06 28.0 3.9 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 GAP85855.1 - 1.8e-06 27.1 33.1 4.4e-06 25.9 33.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3433 PF11915.8 GAP85857.1 - 5.5e-28 97.3 13.4 5.9e-17 61.9 4.5 4.0 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) CrgA PF06781.12 GAP85857.1 - 0.074 13.1 0.1 0.49 10.5 0.0 2.5 3 0 0 3 3 3 0 Cell division protein CrgA AMP_N PF05195.16 GAP85857.1 - 0.21 11.3 0.0 0.65 9.7 0.0 1.7 2 0 0 2 2 2 0 Aminopeptidase P, N-terminal domain DTHCT PF08070.11 GAP85858.1 - 0.0024 18.6 3.8 0.0038 18.0 3.8 1.3 1 0 0 1 1 1 1 DTHCT (NUC029) region SDF PF00375.18 GAP85858.1 - 0.081 11.9 0.0 0.095 11.7 0.0 1.0 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family GDPD PF03009.17 GAP85859.1 - 5.2e-33 114.9 0.0 7.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 GAP85859.1 - 0.084 13.4 1.1 2.9 8.5 0.0 2.8 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family Fungal_trans PF04082.18 GAP85860.1 - 5.2e-35 120.8 0.3 1.1e-34 119.6 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85860.1 - 1.4e-09 37.9 11.7 2.7e-09 37.0 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 GAP85860.1 - 0.047 13.8 0.2 0.14 12.3 0.2 1.8 1 0 0 1 1 1 0 bZIP transcription factor DUF4635 PF15466.6 GAP85860.1 - 0.35 10.4 2.7 0.29 10.7 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) SET PF00856.28 GAP85861.1 - 0.063 13.7 0.0 0.13 12.6 0.0 1.8 1 1 0 1 1 1 0 SET domain MMR_HSR1_C PF08438.10 GAP85862.1 - 7.5e-34 116.7 0.0 1.3e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 GAP85862.1 - 1.9e-21 76.3 0.0 3.9e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAP85862.1 - 2.4e-10 40.2 0.2 1.4e-07 31.2 0.0 2.7 3 0 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 GAP85862.1 - 0.00071 19.2 0.0 0.33 10.5 0.0 2.6 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAP85862.1 - 0.00077 19.4 0.2 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 GAP85862.1 - 0.02 15.4 0.0 0.46 11.0 0.0 2.5 3 0 0 3 3 3 0 ABC transporter Dynamin_N PF00350.23 GAP85862.1 - 0.027 14.5 0.1 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Dynamin family Ploopntkinase3 PF18751.1 GAP85862.1 - 0.08 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 GAP85862.1 - 0.094 11.7 0.2 0.52 9.2 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1_Xtn PF16897.5 GAP85862.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Phage_AlpA PF05930.12 GAP85862.1 - 0.15 11.9 0.5 2.6 7.9 0.8 2.3 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) AAA_28 PF13521.6 GAP85862.1 - 0.16 12.2 0.6 1 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF952 PF06108.12 GAP85863.1 - 1.7e-18 66.4 0.0 2.7e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF952) MDM10 PF12519.8 GAP85866.1 - 0.077 11.8 6.2 0.088 11.7 6.2 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF1387 PF07139.11 GAP85866.1 - 0.87 9.3 11.8 0.92 9.2 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Sin_N PF04801.13 GAP85866.1 - 1.9 7.6 18.6 2.1 7.5 18.6 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Suf PF05843.14 GAP85866.1 - 4.2 7.3 17.2 4.9 7.1 17.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4100 PF13352.6 GAP85866.1 - 4.8 6.9 6.2 0.87 9.3 2.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4100) TFIIA PF03153.13 GAP85866.1 - 5.8 6.8 26.7 7.1 6.5 26.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Asp-B-Hydro_N PF05279.11 GAP85866.1 - 9.8 6.2 9.1 11 6.0 9.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Patatin PF01734.22 GAP85867.1 - 1.9e-08 34.7 0.0 3.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Rib_hydrolayse PF02267.17 GAP85869.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.4 1 1 0 1 1 1 0 ADP-ribosyl cyclase Glyco_hydro_92 PF07971.12 GAP85870.1 - 2.4e-148 494.9 0.4 2.9e-148 494.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAP85870.1 - 6.8e-61 206.2 1.8 1.1e-60 205.6 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Ribosomal_L7Ae PF01248.26 GAP85871.1 - 3.3e-18 65.2 0.5 1.2e-17 63.4 0.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4050 PF13259.6 GAP85871.1 - 0.6 10.4 3.2 0.67 10.2 2.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) DUF1761 PF08570.10 GAP85872.1 - 5.7e-27 94.4 4.0 6.5e-27 94.3 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) STAR_dimer PF16544.5 GAP85872.1 - 0.091 12.3 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein NIF PF03031.18 GAP85873.1 - 1.6e-55 187.1 0.0 2.3e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IMUP PF15761.5 GAP85873.1 - 1.5 9.5 14.5 0.12 13.1 7.5 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein tRNA-synt_1 PF00133.22 GAP85874.1 - 1.5e-207 690.6 0.0 5.5e-206 685.4 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAP85874.1 - 3.8e-29 101.6 0.0 1.2e-28 100.0 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAP85874.1 - 1.9e-15 56.6 0.1 0.00013 20.9 0.0 4.8 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAP85874.1 - 6.3e-13 48.6 3.1 1e-09 38.2 0.0 3.2 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAP85874.1 - 0.055 12.8 0.1 1.1 8.5 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain BrnA_antitoxin PF14384.6 GAP85874.1 - 0.57 10.7 3.3 0.73 10.4 0.0 2.7 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system DNApol_Exo PF18136.1 GAP85874.1 - 2.3 7.3 5.0 14 4.7 4.3 2.1 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain Enkurin PF13864.6 GAP85874.1 - 8.1 6.9 11.4 0.71 10.3 2.4 2.8 2 0 0 2 2 2 0 Calmodulin-binding IF-2B PF01008.17 GAP85875.1 - 4.2e-41 141.0 0.0 6.3e-41 140.4 0.0 1.2 1 1 0 1 1 1 1 Initiation factor 2 subunit family SAPS PF04499.15 GAP85876.1 - 0.21 10.3 0.1 0.32 9.7 0.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mac PF12464.8 GAP85876.1 - 0.67 10.2 7.3 1.9 8.8 7.3 1.8 1 0 0 1 1 1 0 Maltose acetyltransferase DDHD PF02862.17 GAP85876.1 - 1.3 9.2 6.4 0.4 10.8 1.1 2.3 2 0 0 2 2 2 0 DDHD domain Nop53 PF07767.11 GAP85876.1 - 2.9 7.2 38.7 3.7 6.8 13.1 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Acetyltransf_1 PF00583.25 GAP85877.1 - 6.1e-13 49.0 0.0 1.2e-12 48.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAP85877.1 - 2.3e-07 30.7 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAP85877.1 - 8e-07 29.0 0.1 1.2e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP85877.1 - 2.8e-06 27.7 0.0 5.9e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP85877.1 - 0.014 15.5 0.1 0.029 14.4 0.1 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 GAP85877.1 - 0.13 11.7 0.1 0.25 10.8 0.0 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase adh_short PF00106.25 GAP85878.1 - 1.1e-44 152.3 0.0 1.4e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP85878.1 - 3.9e-44 151.0 0.0 4.5e-39 134.4 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP85878.1 - 8.9e-15 55.1 0.0 1.3e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP85878.1 - 0.0086 15.6 0.0 0.046 13.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAP85878.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UFD1 PF03152.14 GAP85878.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Yae1_N PF09811.9 GAP85879.1 - 5.5e-10 38.8 7.0 1.6e-09 37.3 7.0 1.8 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF4449 PF14613.6 GAP85879.1 - 0.053 13.6 1.2 0.07 13.2 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) ANAPC_CDC26 PF10471.9 GAP85879.1 - 0.11 13.3 10.5 0.21 12.5 10.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 PGA2 PF07543.12 GAP85879.1 - 0.16 12.0 3.7 0.28 11.2 3.7 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Spt20 PF12090.8 GAP85879.1 - 0.59 9.7 8.5 0.77 9.3 8.5 1.1 1 0 0 1 1 1 0 Spt20 family CI-B14_5a PF07347.12 GAP85880.1 - 0.027 14.4 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Band_7 PF01145.25 GAP85881.1 - 2.9e-25 89.3 7.5 6.3e-25 88.2 7.5 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 GAP85881.1 - 0.0017 17.5 4.6 0.0023 17.1 4.6 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 GAP85881.1 - 0.022 14.5 0.1 0.037 13.7 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF676 PF05057.14 GAP85883.1 - 4e-53 180.2 0.0 5.7e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 GAP85883.1 - 3.7e-05 23.7 0.0 5.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 GAP85883.1 - 0.00088 19.1 0.0 0.0076 16.0 0.0 2.3 2 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAP85883.1 - 0.0016 19.1 0.0 0.005 17.5 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 GAP85883.1 - 0.0099 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Lipase_2 PF01674.18 GAP85883.1 - 0.053 13.0 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) HhH-GPD PF00730.25 GAP85884.1 - 1.8e-15 57.3 0.0 3.3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAP85884.1 - 1.3e-07 31.1 0.0 3.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Dicty_REP PF05086.12 GAP85884.1 - 0.23 9.4 7.0 0.42 8.5 7.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-AN1 PF01428.16 GAP85885.1 - 3.7e-13 49.4 5.3 3.7e-13 49.4 5.3 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 GAP85885.1 - 0.48 10.8 6.5 0.26 11.7 4.5 1.6 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain ADH_N PF08240.12 GAP85886.1 - 5.1e-26 90.7 1.9 1.5e-25 89.2 1.9 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP85886.1 - 1.1e-19 70.8 1.0 1.9e-19 69.9 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP85886.1 - 0.0024 18.9 0.0 0.0059 17.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAP85886.1 - 0.0033 16.7 0.5 0.0065 15.8 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 GAP85886.1 - 0.0036 16.8 0.1 0.0066 15.9 0.1 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 GAP85886.1 - 0.006 16.8 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 GAP85886.1 - 0.11 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Nucleopor_Nup85 PF07575.13 GAP85887.1 - 5.8e-08 31.8 0.0 2.9e-06 26.2 0.0 2.7 1 1 0 1 1 1 1 Nup85 Nucleoporin Transthyretin PF00576.21 GAP85888.1 - 1e-36 125.9 0.2 1.6e-36 125.3 0.2 1.3 1 1 0 1 1 1 1 HIUase/Transthyretin family YonK PF09642.10 GAP85888.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 YonK protein ArsA_ATPase PF02374.15 GAP85889.1 - 1.5e-111 372.4 0.1 1.7e-111 372.2 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 GAP85889.1 - 6e-14 52.4 0.1 7.7e-13 48.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 GAP85889.1 - 1.5e-12 47.6 0.0 3.1e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 GAP85889.1 - 4e-06 26.5 0.0 1.1e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 GAP85889.1 - 4.8e-06 26.2 0.5 0.00021 20.9 0.1 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 GAP85889.1 - 1.5e-05 24.7 0.0 0.0016 18.1 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 GAP85889.1 - 7e-05 22.4 0.0 0.00025 20.6 0.0 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 GAP85889.1 - 0.011 16.2 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 GAP85889.1 - 0.019 14.5 0.1 0.051 13.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAP85889.1 - 0.15 12.6 0.0 0.44 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 GAP85889.1 - 0.17 11.3 0.1 0.47 9.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Amidohydro_2 PF04909.14 GAP85890.1 - 1.7e-24 87.2 0.0 2e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF4328 PF14219.6 GAP85891.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF4381 PF14316.6 GAP85891.1 - 0.038 14.2 0.2 0.092 13.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Lipase_GDSL_2 PF13472.6 GAP85893.1 - 2.5e-17 63.8 1.0 3.4e-17 63.4 1.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP85893.1 - 9.1e-13 48.6 0.0 1.2e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AvrE_T3Es PF11725.8 GAP85893.1 - 0.15 9.2 0.1 0.19 8.9 0.1 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) Acetyltransf_10 PF13673.7 GAP85894.1 - 4.2e-08 33.2 0.0 6.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP85894.1 - 6.5e-05 23.2 0.0 9.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP85894.1 - 0.00012 22.4 0.0 0.00023 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP85894.1 - 0.0048 17.0 0.0 0.014 15.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP85894.1 - 0.032 14.2 0.0 0.081 12.9 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein COQ7 PF03232.13 GAP85895.1 - 1.5e-70 236.5 0.4 1.7e-70 236.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 GAP85895.1 - 0.0021 18.4 0.0 0.0041 17.5 0.0 1.6 1 1 0 1 1 1 1 Rubrerythrin Vitellogenin_N PF01347.22 GAP85895.1 - 0.075 11.4 0.0 0.096 11.1 0.0 1.2 1 1 0 1 1 1 0 Lipoprotein amino terminal region Plus-3 PF03126.18 GAP85896.1 - 1.7e-29 102.5 0.0 7.3e-29 100.5 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain TssO PF17561.2 GAP85896.1 - 0.085 13.0 0.3 0.085 13.0 0.3 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO YebO PF13974.6 GAP85896.1 - 3.2 7.9 8.1 0.68 10.1 2.9 2.5 2 0 0 2 2 2 0 YebO-like protein Fungal_trans PF04082.18 GAP85897.1 - 1.4e-21 76.7 0.2 2.1e-21 76.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85897.1 - 1.3e-07 31.6 9.6 3e-07 30.4 9.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 GAP85898.1 - 2e-50 171.7 2.8 2.8e-50 171.2 2.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 GAP85898.1 - 1.4e-15 57.0 0.0 3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 GAP85898.1 - 1.4e-12 48.0 1.6 5.9e-11 42.8 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 GAP85898.1 - 1.2e-06 28.9 0.0 3.8e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 GAP85898.1 - 0.0028 16.9 0.1 1.8 7.6 0.0 2.5 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAP85898.1 - 0.042 13.8 1.7 18 5.3 0.0 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 GAP85898.1 - 0.047 13.9 0.2 11 6.3 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain FIST PF08495.10 GAP85898.1 - 0.05 13.6 0.3 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 FIST N domain DivIVA PF05103.13 GAP85899.1 - 0.17 12.0 24.2 7.6 6.6 15.5 4.0 2 1 2 4 4 4 0 DivIVA protein SARAF PF06682.12 GAP85899.1 - 0.28 10.8 7.9 0.023 14.4 1.9 2.2 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Phage_GP20 PF06810.11 GAP85899.1 - 0.44 10.4 17.2 0.043 13.6 1.8 3.8 2 1 1 4 4 4 0 Phage minor structural protein GP20 DUF4763 PF15960.5 GAP85899.1 - 0.5 9.6 24.8 0.24 10.7 5.2 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4763) Bacillus_HBL PF05791.11 GAP85899.1 - 0.63 9.8 9.0 8.9 6.1 2.9 3.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4686 PF15742.5 GAP85899.1 - 0.69 9.0 31.1 0.019 14.1 22.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) V_ATPase_I PF01496.19 GAP85899.1 - 1.2 7.0 12.2 1.8 6.4 12.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.7 GAP85899.1 - 1.4 9.1 29.7 0.29 11.3 24.3 2.5 2 1 1 3 3 3 0 Tropomyosin like SHE3 PF17078.5 GAP85899.1 - 1.4 8.5 25.7 0.13 11.9 6.0 2.6 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 DHR10 PF18595.1 GAP85899.1 - 2.2 8.4 37.1 0.36 10.9 22.8 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain AAA_13 PF13166.6 GAP85899.1 - 2.8 6.5 16.5 5.2 5.6 16.5 1.4 1 0 0 1 1 1 0 AAA domain Lectin_N PF03954.14 GAP85899.1 - 3.6 7.3 14.2 0.37 10.5 2.4 4.3 3 1 2 5 5 5 0 Hepatic lectin, N-terminal domain CHD5 PF04420.14 GAP85899.1 - 4.2 7.2 6.7 14 5.5 6.6 2.0 1 1 0 1 1 1 0 CHD5-like protein HAP1_N PF04849.13 GAP85899.1 - 6.4 5.9 35.5 1.2 8.3 0.1 3.0 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Fib_alpha PF08702.10 GAP85899.1 - 6.6 6.9 19.8 1.6 8.9 6.0 3.3 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family GAS PF13851.6 GAP85899.1 - 8.9 5.6 30.8 4.2 6.7 11.4 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding PLDc PF00614.22 GAP85900.1 - 2.5e-17 62.3 0.4 1.3e-07 31.4 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 GAP85900.1 - 4.9e-14 52.3 0.0 5.3e-07 29.6 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 GAP85900.1 - 5e-09 36.1 0.0 3.5e-08 33.4 0.0 2.5 1 1 0 1 1 1 1 PX domain DNAPolymera_Pol PF11590.8 GAP85900.1 - 0.18 11.7 3.7 15 5.6 0.8 2.9 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol MFS_1 PF07690.16 GAP85901.1 - 7.8e-27 94.1 34.4 1.4e-25 90.0 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRP PF06011.12 GAP85902.1 - 4.6e-35 121.2 22.8 2.9e-34 118.5 22.8 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 GAP85902.1 - 1.8e-17 64.0 0.0 4.2e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 ML-like domain Cys_Met_Meta_PP PF01053.20 GAP85903.1 - 5.8e-55 186.4 0.0 1.2e-54 185.3 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAP85903.1 - 0.03 13.3 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V WBS_methylT PF12589.8 GAP85904.1 - 2.4e-13 50.6 4.8 4.5e-13 49.7 4.8 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 GAP85904.1 - 2.9e-11 43.8 0.0 5.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP85904.1 - 1.2e-09 38.7 0.0 2.8e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAP85904.1 - 0.00019 21.2 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GAP85904.1 - 0.00053 19.8 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP85904.1 - 0.00063 20.4 0.0 0.0019 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP85904.1 - 0.0016 18.3 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAP85904.1 - 0.012 15.0 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 GAP85904.1 - 0.058 12.7 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Erv26 PF04148.13 GAP85905.1 - 7.3e-92 306.8 3.0 8.4e-92 306.6 3.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.20 GAP85905.1 - 0.019 14.7 2.4 0.019 14.7 2.4 1.9 2 1 0 2 2 2 0 Cytochrome C assembly protein DUF3377 PF11857.8 GAP85905.1 - 0.11 12.4 0.9 0.72 9.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Pox_A9 PF04835.12 GAP85905.1 - 0.17 12.1 2.5 0.34 11.1 0.5 2.4 2 0 0 2 2 2 0 A9 protein conserved region RNase_T PF00929.24 GAP85906.1 - 2.1e-11 44.7 0.0 6.3e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Exonuclease HTH_15 PF12324.8 GAP85906.1 - 0.13 12.2 0.8 10 6.2 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase MCM PF00493.23 GAP85907.1 - 1.2e-103 345.1 0.7 1.7e-103 344.5 0.7 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAP85907.1 - 5.7e-40 136.1 0.2 1.1e-39 135.1 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 GAP85907.1 - 5.3e-33 113.5 0.0 1.2e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 GAP85907.1 - 3.6e-24 85.0 0.1 1.4e-23 83.1 0.1 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAP85907.1 - 1.7e-23 83.1 2.5 2.2e-23 82.8 0.6 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAP85907.1 - 8.6e-08 31.8 0.0 7.3e-07 28.8 0.1 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAP85907.1 - 0.00081 19.2 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAP85907.1 - 0.00094 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 GAP85907.1 - 0.035 14.1 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) F1F0-ATPsyn_F PF10791.9 GAP85909.1 - 4.6e-40 136.0 0.2 5.2e-40 135.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi ETC_C1_NDUFA4 PF04800.12 GAP85910.1 - 7.5e-37 125.5 1.1 1.1e-36 124.9 1.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region CLTH PF10607.9 GAP85911.1 - 2.1e-35 121.8 1.9 3.1e-35 121.3 1.9 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GAP85911.1 - 6e-08 32.4 0.1 5.1e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 LisH DUF3349 PF11829.8 GAP85911.1 - 0.055 14.3 0.7 20 6.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3349) FOP_dimer PF09398.10 GAP85911.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 FOP N terminal dimerisation domain TPR_20 PF14561.6 GAP85911.1 - 0.2 12.0 1.7 0.52 10.7 0.3 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat PRK PF00485.18 GAP85912.1 - 1.8e-58 197.5 0.0 2.5e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 GAP85912.1 - 3e-38 131.3 0.0 4.7e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 GAP85912.1 - 4.8e-05 23.9 0.0 0.00024 21.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 GAP85912.1 - 0.00015 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 GAP85912.1 - 0.00034 20.8 0.0 0.0016 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAP85912.1 - 0.0031 17.9 0.1 3.1 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 GAP85912.1 - 0.0034 17.9 0.3 0.017 15.6 0.2 2.0 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 GAP85912.1 - 0.006 15.9 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 GAP85912.1 - 0.024 14.3 0.7 0.052 13.3 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.22 GAP85912.1 - 0.048 12.8 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 GAP85912.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 GAP85912.1 - 0.074 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 GAP85912.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 GAP85912.1 - 0.12 12.2 0.1 8.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Cytidylate_kin PF02224.18 GAP85912.1 - 0.15 11.7 0.2 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase TIP41 PF04176.13 GAP85912.1 - 0.16 11.5 0.2 6 6.3 0.0 2.5 2 0 0 2 2 2 0 TIP41-like family Abhydrolase_6 PF12697.7 GAP85913.1 - 2.4e-15 57.7 2.5 3.3e-15 57.3 2.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 GAP85913.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF900 PF05990.12 GAP85913.1 - 0.098 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) BAR_2 PF10455.9 GAP85914.1 - 7.1e-60 202.6 0.5 1e-59 202.1 0.5 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 GAP85914.1 - 1.3e-22 80.6 3.1 1.8e-21 76.9 3.1 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 GAP85914.1 - 0.0017 18.1 0.8 0.0065 16.2 0.1 2.1 2 0 0 2 2 2 1 BAR domain of APPL family YdjC PF04794.12 GAP85914.1 - 0.075 13.0 1.2 0.13 12.2 0.4 1.7 1 1 0 1 1 1 0 YdjC-like protein Mod_r PF07200.13 GAP85914.1 - 1.7 8.7 6.3 0.73 9.9 0.1 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ETC_C1_NDUFA5 PF04716.14 GAP85915.1 - 3e-25 87.8 4.7 2.9e-23 81.4 0.1 2.7 3 0 0 3 3 3 2 ETC complex I subunit conserved region DUF4731 PF15875.5 GAP85915.1 - 0.21 11.8 0.0 0.47 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) RNA_pol_I_TF PF04090.12 GAP85916.1 - 3.7e-09 36.4 0.0 4.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor Yip1 PF04893.17 GAP85917.1 - 0.00052 19.8 0.7 0.00069 19.4 0.7 1.3 1 1 0 1 1 1 1 Yip1 domain PAS PF00989.25 GAP85918.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_3 PF08447.12 GAP85918.1 - 0.092 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold DUF3439 PF11921.8 GAP85919.1 - 0.51 10.3 6.7 1 9.3 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 GAP85919.1 - 0.81 7.8 7.0 1.1 7.4 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 LysM PF01476.20 GAP85920.1 - 3.2e-16 59.1 2.9 6.9e-07 29.2 0.1 6.4 7 0 0 7 7 7 3 LysM domain CxC6 PF18721.1 GAP85920.1 - 0.12 12.7 0.9 0.45 10.8 0.3 2.4 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Med3 PF11593.8 GAP85920.1 - 0.31 10.2 7.1 0.85 8.7 7.1 1.7 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sporozoite_P67 PF05642.11 GAP85920.1 - 6.2 4.8 6.8 13 3.7 6.8 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_18 PF00704.28 GAP85921.1 - 1.5e-71 241.7 2.6 2.5e-71 240.9 2.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 GAP85921.1 - 1.3e-12 48.0 14.5 1.3e-12 48.0 14.5 4.0 4 0 0 4 4 4 1 Chitin recognition protein zf-C2H2 PF00096.26 GAP85922.1 - 5.3e-12 45.5 14.5 2e-06 27.9 0.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP85922.1 - 3e-08 33.8 9.2 0.0023 18.6 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAP85922.1 - 1.4e-07 31.6 11.8 7.2e-07 29.4 4.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAP85922.1 - 2.5e-06 27.6 3.7 0.0015 18.7 0.7 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP85922.1 - 1.7e-05 25.0 9.3 0.00011 22.4 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GAP85922.1 - 0.00057 19.8 8.9 0.0066 16.4 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger MAS20 PF02064.15 GAP85922.1 - 0.026 14.6 0.4 0.061 13.4 0.4 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor zf_C2H2_ZHX PF18387.1 GAP85922.1 - 0.028 14.0 3.8 1.6 8.4 0.2 2.6 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_UBZ PF18439.1 GAP85922.1 - 0.072 12.7 2.0 3.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 GAP85922.1 - 0.094 12.8 5.6 0.061 13.4 1.6 2.4 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 GAP85922.1 - 0.36 10.6 5.6 9.5 6.1 0.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 GAP85922.1 - 1.9 8.7 5.2 10 6.4 0.6 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 GAP85922.1 - 2.3 8.9 5.6 28 5.4 2.8 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 GAP85922.1 - 8.7 6.9 7.1 97 3.5 7.1 2.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 GAP85922.1 - 9.1 6.3 8.0 6.7 6.7 2.6 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Diphthami_syn_2 PF01902.17 GAP85923.1 - 9.8e-18 64.4 0.0 2.1e-06 27.4 0.0 4.1 4 0 0 4 4 4 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 GAP85923.1 - 1.9e-05 24.6 0.0 0.0017 18.4 0.0 3.3 4 0 0 4 4 4 1 Endoribonuclease L-PSP Trypan_PARP PF05887.11 GAP85923.1 - 0.022 14.8 1.7 0.11 12.5 2.3 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SOG2 PF10428.9 GAP85923.1 - 0.14 11.4 10.7 0.21 10.7 10.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 GAP85923.1 - 1.9 8.3 10.6 3.5 7.4 10.6 1.4 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 GAP85923.1 - 7.5 5.3 7.0 11 4.7 7.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Polysacc_lyase PF14099.6 GAP85924.1 - 2e-52 178.1 10.7 2.3e-52 177.9 10.7 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Triabin PF03973.13 GAP85924.1 - 0.038 13.9 0.1 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 Triabin Tim17 PF02466.19 GAP85925.1 - 7.1e-15 55.4 1.0 1.4e-14 54.3 0.9 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 GAP85925.1 - 0.025 14.7 3.2 4.1 7.6 1.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5518) CAP59_mtransfer PF11735.8 GAP85926.1 - 4.5e-78 262.3 0.0 5.6e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Methyltransf_11 PF08241.12 GAP85927.1 - 1.5e-12 48.0 0.0 2.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP85927.1 - 8.5e-11 42.4 0.0 1.7e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP85927.1 - 5e-06 26.4 0.0 1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP85927.1 - 0.00012 22.7 0.0 0.00021 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP85927.1 - 0.00018 20.9 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 GAP85927.1 - 0.00065 19.5 0.0 0.0058 16.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 GAP85927.1 - 0.013 15.1 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 GAP85927.1 - 0.028 14.3 0.0 0.075 12.9 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase LSM PF01423.22 GAP85928.1 - 1.3e-20 72.8 0.2 1.7e-20 72.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAP85928.1 - 0.00021 21.4 0.1 0.00025 21.1 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 GAP85928.1 - 0.00035 20.6 0.2 0.00042 20.4 0.2 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain IceA2 PF05862.11 GAP85928.1 - 0.071 13.1 1.5 0.14 12.1 0.2 2.0 1 1 1 2 2 2 0 Helicobacter pylori IceA2 protein Rad60-SLD PF11976.8 GAP85929.1 - 7.4e-11 41.7 0.2 1.9e-10 40.4 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TmoB PF06234.12 GAP85929.1 - 0.00096 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Toluene-4-monooxygenase system protein B (TmoB) Cellulase PF00150.18 GAP85930.1 - 1.5e-39 136.1 0.1 1.8e-39 135.9 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribonucleas_3_3 PF14622.6 GAP85931.1 - 7.9e-12 45.5 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 GAP85931.1 - 1.1e-09 38.8 0.0 1e-08 35.7 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease III domain Kdo PF06293.14 GAP85932.1 - 2.4e-06 27.0 0.1 4.1e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP85932.1 - 0.00013 22.0 0.5 0.00053 20.0 0.5 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAP85932.1 - 0.0025 17.2 0.2 0.0037 16.7 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 GAP85932.1 - 0.0047 16.5 0.1 0.0097 15.5 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 GAP85932.1 - 0.036 12.8 0.3 0.058 12.2 0.3 1.2 1 0 0 1 1 1 0 Fungal protein kinase WaaY PF06176.11 GAP85932.1 - 0.036 13.7 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) FTA2 PF13095.6 GAP85932.1 - 0.072 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 GAP85932.1 - 0.15 11.6 0.2 3.4 7.2 0.3 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase 7tm_2 PF00002.24 GAP85933.1 - 7.4e-07 28.7 11.9 7.6e-07 28.7 9.7 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 GAP85933.1 - 5e-05 22.6 3.7 9.2e-05 21.7 3.7 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor NICE-3 PF07406.11 GAP85933.1 - 2 8.4 4.1 34 4.4 0.0 2.3 2 0 0 2 2 2 0 NICE-3 protein UL42 PF17638.2 GAP85933.1 - 8.8 6.3 8.4 14 5.7 3.5 2.6 2 0 0 2 2 2 0 HCMV UL42 G_path_suppress PF15991.5 GAP85933.1 - 10 6.2 12.5 16 5.6 12.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor HET PF06985.11 GAP85934.1 - 2.1e-14 54.1 2.7 2.1e-14 54.1 2.7 2.9 3 1 0 3 3 3 1 Heterokaryon incompatibility protein (HET) GEN1_C PF18380.1 GAP85934.1 - 0.062 14.2 2.2 0.17 12.8 2.2 1.7 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Helicase_C PF00271.31 GAP85935.1 - 5.7e-22 78.2 0.2 1.2e-21 77.1 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP85935.1 - 1.2e-21 77.5 0.0 2.5e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAP85935.1 - 1.9e-16 60.3 0.0 4.6e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAP85935.1 - 0.00022 21.5 0.0 0.00068 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain ART PF01129.18 GAP85935.1 - 0.029 13.7 0.0 0.34 10.2 0.0 2.1 1 1 1 2 2 2 0 NAD:arginine ADP-ribosyltransferase TAP_C PF03943.13 GAP85936.1 - 1.8e-17 62.7 0.5 4.2e-17 61.5 0.5 1.7 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 GAP85936.1 - 1.2e-05 25.0 0.1 0.0001 22.0 0.0 2.4 2 0 0 2 2 2 1 UBA-like domain RRM_9 PF18444.1 GAP85936.1 - 1.9e-05 24.4 0.0 7e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif LRR_9 PF14580.6 GAP85936.1 - 0.00068 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.20 GAP85936.1 - 0.021 15.4 0.0 0.082 13.5 0.0 2.1 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 GAP85936.1 - 0.46 11.0 5.1 0.41 11.1 0.9 2.5 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Kelch_6 PF13964.6 GAP85937.1 - 0.00034 20.8 2.1 0.019 15.2 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Cadherin_C_2 PF16492.5 GAP85937.1 - 0.0081 16.9 0.0 0.044 14.5 0.0 2.2 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal Rax2 PF12768.7 GAP85937.1 - 0.022 14.2 0.1 0.078 12.4 0.1 2.0 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.6 GAP85937.1 - 0.036 14.0 0.2 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 TMEM154 protein family Podoplanin PF05808.11 GAP85937.1 - 0.051 13.7 0.2 0.14 12.3 0.2 1.8 1 0 0 1 1 1 0 Podoplanin Kelch_4 PF13418.6 GAP85937.1 - 0.055 13.5 3.7 5.7 7.0 0.0 4.3 4 1 0 4 4 4 0 Galactose oxidase, central domain STE2 PF02116.15 GAP85937.1 - 0.084 12.2 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR DUF4381 PF14316.6 GAP85937.1 - 0.2 11.9 1.0 0.27 11.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM51 PF15345.6 GAP85937.1 - 6.3 6.6 6.7 22 4.8 0.5 2.4 1 1 0 2 2 2 0 Transmembrane protein 51 MSC PF09402.10 GAP85938.1 - 5.4e-102 341.7 0.2 2e-101 339.8 0.2 1.8 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 GAP85938.1 - 8e-16 57.5 0.0 1.4e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 GAP85938.1 - 0.00087 18.8 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Thymopoietin protein HLH PF00010.26 GAP85939.1 - 3.2e-16 59.0 0.0 1.2e-15 57.2 0.0 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tropomyosin PF00261.20 GAP85939.1 - 0.34 10.3 15.2 0.047 13.0 1.1 2.2 2 0 0 2 2 2 0 Tropomyosin AAA_23 PF13476.6 GAP85939.1 - 2.7 8.4 18.4 0.69 10.4 11.7 2.2 2 0 0 2 2 2 0 AAA domain Peptidase_S49_N PF08496.10 GAP85939.1 - 4.5 7.3 8.6 11 6.0 8.6 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal APG6_N PF17675.1 GAP85939.1 - 4.6 7.8 26.3 6 7.4 20.2 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Peptidase_S30 PF01577.16 GAP85939.1 - 5.6 6.5 15.3 1.8 8.1 0.2 2.5 2 0 0 2 2 2 0 Potyvirus P1 protease ARGLU PF15346.6 GAP85939.1 - 9.5 6.1 26.8 5 7.0 20.5 2.4 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 SHR3_chaperone PF08229.11 GAP85940.1 - 5.1e-76 253.9 0.0 6e-76 253.6 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 GAP85940.1 - 0.011 15.7 2.7 0.024 14.6 0.7 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5453) DUF2157 PF09925.9 GAP85940.1 - 0.11 12.3 3.0 12 5.7 0.0 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Alpha_GJ PF03229.13 GAP85941.1 - 4.2e-05 24.1 9.3 4.2e-05 24.1 9.3 2.2 2 0 0 2 2 2 1 Alphavirus glycoprotein J Granulin PF00396.18 GAP85941.1 - 7.2 7.0 30.1 0.68 10.3 6.3 3.4 2 1 1 3 3 3 0 Granulin HAD_2 PF13419.6 GAP85942.1 - 6.7e-11 42.6 0.0 1.2e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP85942.1 - 2.5e-07 31.2 0.0 1.2e-06 29.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP85942.1 - 1.4e-06 28.3 0.1 2.8e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Fungal_trans_2 PF11951.8 GAP85943.1 - 4.3e-81 272.7 1.1 5.6e-81 272.3 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain FerI PF08151.12 GAP85943.1 - 0.077 13.1 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 FerI (NUC094) domain SAM_2 PF07647.17 GAP85944.1 - 5.9e-06 26.3 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAP85944.1 - 7.7e-06 26.3 0.1 4e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 GAP85944.1 - 0.00018 22.0 0.0 0.00069 20.1 0.0 2.0 1 1 0 1 1 1 1 PH domain Sod_Fe_C PF02777.18 GAP85945.1 - 2.7e-19 69.2 0.0 1e-08 35.3 0.0 2.6 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Mito_carr PF00153.27 GAP85947.1 - 1.3e-60 201.3 1.0 1.2e-19 70.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAP85947.1 - 2.2 7.4 6.0 1.8 7.6 0.3 3.1 4 0 0 4 4 4 0 Gammaproteobacterial serine protease ApoO PF09769.9 GAP85948.1 - 1.9e-39 134.6 0.1 6.3e-39 132.9 0.0 1.8 2 0 0 2 2 2 1 Apolipoprotein O Peptidase_M3 PF01432.20 GAP85949.1 - 7.7e-127 424.3 0.1 1.2e-126 423.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M3 O-FucT PF10250.9 GAP85949.1 - 0.0044 16.8 0.5 0.0077 16.0 0.2 1.6 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase eIF3_N PF09440.10 GAP85949.1 - 0.088 13.3 2.7 9 6.7 0.0 2.9 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain Peptidase_M50B PF13398.6 GAP85949.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like WSC PF01822.19 GAP85950.1 - 1.3e-16 60.5 2.5 1.3e-16 60.5 2.5 1.8 2 0 0 2 2 2 1 WSC domain IMS PF00817.20 GAP85951.1 - 5.9e-38 130.2 0.0 1.2e-37 129.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 GAP85951.1 - 3.2e-25 88.4 0.3 5.9e-25 87.5 0.3 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 GAP85951.1 - 2.1e-14 52.4 10.7 1.7e-06 27.2 1.3 3.8 3 0 0 3 3 3 3 Ubiquitin binding region IMS_C PF11799.8 GAP85951.1 - 7.2e-13 49.3 0.0 2.7e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 GAP85951.1 - 1.3e-05 25.5 0.0 4.1e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain mCpol PF18182.1 GAP85951.1 - 0.0025 18.1 0.0 0.0066 16.8 0.0 1.7 1 0 0 1 1 1 1 minimal CRISPR polymerase domain IMS_HHH PF11798.8 GAP85951.1 - 0.007 16.6 0.3 0.031 14.6 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif F420_ligase PF01996.16 GAP85951.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase MgtE_N PF03448.17 GAP85951.1 - 0.032 14.8 0.5 4.6 7.9 0.0 3.3 2 1 0 2 2 2 0 MgtE intracellular N domain BRCT PF00533.26 GAP85951.1 - 0.06 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain RED_N PF07808.13 GAP85952.1 - 1.3e-06 28.2 7.7 1.3e-06 28.2 7.7 2.6 3 0 0 3 3 3 1 RED-like protein N-terminal region DUF2924 PF11149.8 GAP85952.1 - 0.57 10.6 2.6 1.2 9.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) IU_nuc_hydro PF01156.19 GAP85953.1 - 1.1e-18 67.8 0.1 1.3e-18 67.7 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.19 GAP85954.1 - 1.9e-14 54.0 0.0 2.1e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Mago-bind PF09282.10 GAP85955.1 - 8.7e-13 47.9 2.2 2.4e-12 46.5 2.2 1.8 1 0 0 1 1 1 1 Mago binding zf-UBR PF02207.20 GAP85956.1 - 4.2e-19 68.5 15.7 1.1e-18 67.1 15.7 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 GAP85956.1 - 0.00016 21.4 0.0 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DNA_pol_phi PF04931.13 GAP85956.1 - 0.42 8.7 16.6 0.93 7.5 16.6 1.5 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 GAP85957.1 - 3.5e-54 179.6 14.2 1.6e-09 38.3 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP85957.1 - 6.3e-21 74.5 0.0 0.0048 17.2 0.0 6.9 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP85957.1 - 6.9e-06 25.3 0.1 1.7 7.5 0.0 4.9 1 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAP85957.1 - 8e-06 25.9 0.0 0.0036 17.2 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 GAP85957.1 - 0.00039 19.6 0.0 0.74 8.8 0.0 3.6 1 1 3 4 4 4 2 VID27 C-terminal WD40-like domain Nup160 PF11715.8 GAP85957.1 - 0.00098 17.9 6.9 0.33 9.5 0.1 4.5 3 2 2 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 GAP85957.1 - 0.0024 17.3 0.0 0.27 10.5 0.0 2.3 1 1 0 2 2 2 1 WD40-like domain PD40 PF07676.12 GAP85957.1 - 0.0031 17.4 6.0 2.3 8.3 0.0 5.2 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 GAP85957.1 - 0.023 13.3 0.0 0.14 10.6 0.0 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain Frtz PF11768.8 GAP85957.1 - 0.052 11.9 0.0 0.32 9.3 0.0 1.9 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Apt1 PF10351.9 GAP85957.1 - 1.7 7.4 16.9 2.2 7.1 16.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain QWRF PF04484.12 GAP85957.1 - 4.7 6.9 17.9 7.3 6.2 17.9 1.4 1 0 0 1 1 1 0 QWRF family Exo_endo_phos PF03372.23 GAP85958.1 - 2e-12 47.1 0.1 4.4e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 GAP85959.1 - 5.1e-53 180.1 0.0 7e-32 110.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP85959.1 - 6.5e-26 91.2 0.0 6.1e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GAP85959.1 - 0.0013 18.7 3.7 0.042 13.8 0.3 3.3 2 1 0 3 3 3 1 Phosphotransferase enzyme family TFIIA PF03153.13 GAP85959.1 - 0.068 13.2 5.5 0.18 11.8 5.5 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 GAP85959.1 - 0.3 10.8 1.2 0.72 9.5 1.2 1.6 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 GAP85959.1 - 1.5 6.8 6.3 2.2 6.3 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 GAP85959.1 - 1.6 6.9 4.7 2.5 6.2 4.7 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 GAP85959.1 - 4.5 7.7 15.8 14 6.2 15.8 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FKBP_C PF00254.28 GAP85960.1 - 9.8e-32 109.2 0.1 5.3e-31 106.8 0.1 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 GAP85960.1 - 7.8e-29 100.3 0.3 2.8e-28 98.6 0.0 2.1 2 0 0 2 2 2 1 Nucleoplasmin-like domain DJ-1_PfpI PF01965.24 GAP85961.1 - 9e-09 35.3 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_trans_2_3 PF13632.6 GAP85962.1 - 2.3e-21 76.6 0.2 2.3e-21 76.6 0.2 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 FmiP_Thoc5 PF09766.9 GAP85963.1 - 8e-32 110.9 12.6 9.8e-32 110.6 12.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 GAP85963.1 - 0.037 14.1 9.2 0.049 13.7 4.3 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus K-box PF01486.17 GAP85963.1 - 0.06 13.5 0.8 0.06 13.5 0.8 2.9 3 1 0 3 3 3 0 K-box region DUF87 PF01935.17 GAP85963.1 - 0.073 13.2 2.4 0.095 12.8 2.4 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain CENP-F_leu_zip PF10473.9 GAP85963.1 - 0.61 10.1 14.0 3.4 7.7 6.9 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Casc1_N PF15927.5 GAP85963.1 - 8.3 6.0 15.3 0.064 12.9 4.9 2.2 2 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DOR PF14839.6 GAP85963.1 - 9.6 6.1 7.5 0.52 10.2 1.7 1.7 2 0 0 2 2 2 0 DOR family HlyIII PF03006.20 GAP85964.1 - 2.1e-61 207.5 18.5 3.1e-61 207.0 18.5 1.2 1 0 0 1 1 1 1 Haemolysin-III related RabGAP-TBC PF00566.18 GAP85965.1 - 6.6e-31 107.6 0.0 9.6e-26 90.8 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain REV PF00424.18 GAP85965.1 - 0.12 12.4 5.8 0.36 10.9 5.8 1.9 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Sulfate_transp PF00916.20 GAP85966.1 - 3.8e-109 364.9 23.1 5e-109 364.5 23.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAP85966.1 - 9.4e-07 28.5 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAP85966.1 - 0.003 18.0 3.2 0.003 18.0 3.2 4.0 3 2 1 4 4 4 1 Molybdate transporter of MFS superfamily DUF1096 PF06493.11 GAP85967.1 - 0.0048 17.3 3.0 0.0099 16.3 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1096) SWIM PF04434.17 GAP85967.1 - 0.14 11.8 0.7 0.29 10.9 0.7 1.5 1 0 0 1 1 1 0 SWIM zinc finger Pkinase PF00069.25 GAP85968.1 - 1.9e-05 24.2 0.1 3.7e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.18 GAP85969.1 - 5.1 7.3 13.2 0.069 13.3 5.3 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 GAP85970.1 - 1.3e-21 77.6 0.4 1.7e-21 77.2 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 GAP85970.1 - 0.029 13.5 0.1 0.044 12.9 0.1 1.1 1 0 0 1 1 1 0 CsiD Fungal_trans PF04082.18 GAP85971.1 - 1.6e-41 142.1 0.1 4.8e-41 140.6 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85971.1 - 1.9e-08 34.3 5.7 3.7e-08 33.4 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipin_mid PF16876.5 GAP85971.1 - 0.035 14.2 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain MFS_1 PF07690.16 GAP85972.1 - 8.2e-39 133.5 24.0 8.2e-39 133.5 24.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP85972.1 - 5e-11 42.1 4.9 5e-11 42.1 4.9 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAP85972.1 - 0.00045 18.8 0.8 0.00078 18.0 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) S4 PF01479.25 GAP85973.1 - 9e-15 54.1 0.0 1.8e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain Septin PF00735.18 GAP85974.1 - 5e-120 400.0 0.1 5e-120 400.0 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 GAP85974.1 - 1.6e-08 34.6 1.0 3.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP85974.1 - 8.6e-05 22.5 2.4 0.0034 17.3 0.7 3.2 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 GAP85974.1 - 0.00012 21.6 1.9 0.0026 17.3 0.0 2.9 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 GAP85974.1 - 0.00022 21.7 2.3 0.031 14.8 0.0 2.7 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 GAP85974.1 - 0.0025 18.2 0.1 0.0069 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 GAP85974.1 - 0.0049 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 GAP85974.1 - 0.0073 15.7 2.6 0.0095 15.3 0.0 2.4 3 0 0 3 3 3 1 AIG1 family AAA_29 PF13555.6 GAP85974.1 - 0.016 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 GAP85974.1 - 0.017 14.8 0.0 0.075 12.6 0.0 2.1 2 0 0 2 2 2 0 Ras family AAA_22 PF13401.6 GAP85974.1 - 0.02 15.2 1.0 0.057 13.7 0.0 2.2 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GAP85974.1 - 0.066 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 GAP85974.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 GAP85974.1 - 0.098 12.7 7.1 1.2 9.1 0.0 3.5 3 1 0 3 3 3 0 Dynamin family RNA_helicase PF00910.22 GAP85974.1 - 0.11 12.9 0.7 0.81 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 GAP85974.1 - 0.12 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 GAP85974.1 - 0.44 11.0 6.4 21 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 GAP85974.1 - 0.97 9.2 3.3 17 5.1 0.0 3.0 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 GAP85974.1 - 1.1 8.8 7.4 1.7 8.1 7.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PPR_3 PF13812.6 GAP85977.1 - 4.8e-11 42.6 0.1 2.2e-05 24.4 0.0 4.2 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 GAP85977.1 - 3.1e-08 33.3 0.7 0.0074 15.7 0.1 3.5 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 GAP85977.1 - 2e-07 31.1 0.0 0.11 12.7 0.0 5.2 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.20 GAP85977.1 - 9.9e-06 25.5 1.1 0.37 11.1 0.0 4.8 6 0 0 6 6 6 2 PPR repeat LSM PF01423.22 GAP85978.1 - 1.8e-16 59.5 0.0 2.4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAP85978.1 - 0.027 14.6 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain SAP18 PF06487.12 GAP85978.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 1 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) DUF1180 PF06679.12 GAP85979.1 - 0.072 13.5 0.5 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) HemY_N PF07219.13 GAP85979.1 - 0.18 12.0 3.3 0.37 11.0 3.3 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Zn_clus PF00172.18 GAP85980.1 - 1.2e-08 34.9 9.3 2.4e-08 33.9 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ku PF02735.16 GAP85981.1 - 3.5e-43 147.7 0.0 1.1e-42 146.1 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 GAP85981.1 - 4.7e-25 88.6 0.0 7.5e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 GAP85981.1 - 1.8e-21 76.6 0.0 5.1e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 GAP85981.1 - 3.4e-11 42.6 0.7 7.2e-11 41.6 0.7 1.6 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.13 GAP85981.1 - 0.006 16.0 0.1 0.0099 15.2 0.1 1.2 1 0 0 1 1 1 1 LETM1-like protein Complex1_51K PF01512.17 GAP85981.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Ferrochelatase PF00762.19 GAP85982.1 - 9.4e-100 333.7 0.0 1.1e-99 333.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.16 GAP85983.1 - 6.8e-23 81.2 36.0 2.4e-18 66.2 21.4 2.5 2 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP85983.1 - 6.3e-09 35.2 1.1 6.3e-09 35.2 1.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF5326 PF17260.2 GAP85983.1 - 0.00091 19.3 0.6 0.00091 19.3 0.6 4.4 5 1 0 5 5 5 1 Family of unknown function (DUF5326) ATG22 PF11700.8 GAP85983.1 - 0.0074 15.0 0.3 0.0074 15.0 0.3 2.3 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like OATP PF03137.20 GAP85983.1 - 0.013 13.8 5.6 0.24 9.7 5.6 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family YajC PF02699.15 GAP85983.1 - 1.4 8.9 3.9 8 6.4 0.6 2.5 2 0 0 2 2 2 0 Preprotein translocase subunit Ank_2 PF12796.7 GAP85984.1 - 1.4e-11 44.8 0.0 2.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP85984.1 - 8.3e-11 41.9 0.6 9.3e-07 29.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAP85984.1 - 3.4e-10 40.2 0.1 5.9e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP85984.1 - 1.8e-09 37.0 0.8 8.9e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 GAP85984.1 - 1.1e-08 35.2 1.2 1.9e-06 28.0 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat bZIP_1 PF00170.21 GAP85984.1 - 0.0051 16.9 7.0 0.0096 16.0 7.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor PSD5 PF07637.11 GAP85984.1 - 0.12 12.8 0.6 0.21 11.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) Csm1_N PF18504.1 GAP85984.1 - 0.16 12.3 2.0 0.33 11.3 2.0 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain SepSecS PF05889.13 GAP85984.1 - 0.2 10.3 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS OrsD PF12013.8 GAP85984.1 - 0.26 11.8 3.4 7.5 7.0 0.4 3.2 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D M16C_assoc PF08367.11 GAP85984.1 - 0.47 9.5 4.3 0.65 9.1 4.3 1.1 1 0 0 1 1 1 0 Peptidase M16C associated bZIP_Maf PF03131.17 GAP85984.1 - 5.7 7.5 12.3 0.23 12.0 6.2 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor Lipase_GDSL_2 PF13472.6 GAP85985.1 - 1.3e-17 64.8 0.1 2e-17 64.2 0.1 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 GAP85985.1 - 0.091 12.9 0.0 0.88 9.7 0.0 2.4 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family Amidohydro_1 PF01979.20 GAP85986.1 - 1.1e-71 242.0 0.0 4.4e-71 240.0 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAP85986.1 - 1.2e-07 31.6 1.0 6.1e-05 22.7 0.1 2.8 2 1 0 2 2 2 2 Amidohydrolase family DUF1729 PF08354.10 GAP85987.1 - 1e-158 527.9 0.0 1.6e-158 527.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 GAP85987.1 - 1.1e-86 291.3 0.0 5.2e-85 285.7 0.0 3.0 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 GAP85987.1 - 3.8e-54 182.5 0.0 1e-53 181.1 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 GAP85987.1 - 8.5e-41 139.0 0.0 7.7e-40 135.9 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 GAP85987.1 - 6.4e-38 129.1 0.0 1.5e-37 127.9 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 GAP85987.1 - 8.5e-37 127.2 0.0 1.9e-36 126.0 0.0 1.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 GAP85987.1 - 1.7e-22 80.0 0.0 8.3e-22 77.7 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.15 GAP85987.1 - 0.26 10.7 1.8 4.1 6.7 1.8 2.4 1 1 0 1 1 1 0 Nitronate monooxygenase FAS_I_H PF18314.1 GAP85988.1 - 4e-76 255.2 0.0 7.9e-76 254.2 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 GAP85988.1 - 5.3e-73 244.7 0.0 9.9e-73 243.8 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ACPS PF01648.20 GAP85988.1 - 1.2e-19 70.5 0.0 2.7e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ketoacyl-synt PF00109.26 GAP85988.1 - 7e-19 68.4 0.0 1.5e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAP85988.1 - 1.2e-10 41.5 0.0 2.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 GAP85988.1 - 0.00014 21.4 0.0 0.00058 19.4 0.0 2.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP85988.1 - 0.00049 20.0 0.0 0.015 15.2 0.0 2.9 3 0 0 3 3 3 1 KR domain RGS_DHEX PF18148.1 GAP85988.1 - 0.11 12.6 0.6 0.49 10.5 0.6 2.1 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain AA_permease_2 PF13520.6 GAP85989.1 - 4.6e-72 243.2 41.2 5.4e-72 242.9 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP85989.1 - 9.3e-20 70.7 32.6 1.1e-19 70.4 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease Lipoxygenase PF00305.19 GAP85990.1 - 1.7e-16 59.9 0.0 1.5e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Lipoxygenase DUF4329 PF14220.6 GAP85990.1 - 0.11 12.5 0.0 0.52 10.3 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4329) Zn_clus PF00172.18 GAP85991.1 - 2.7e-08 33.8 8.2 4.5e-08 33.1 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MBD_C PF14048.6 GAP85991.1 - 0.02 15.6 0.0 0.087 13.5 0.0 2.0 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF268 PF03269.14 GAP85991.1 - 0.061 13.2 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 Clr5 PF14420.6 GAP85992.1 - 8.4e-12 45.1 0.1 1.7e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Clr5 domain Phage_NinH PF06322.11 GAP85992.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Phage NinH protein Adeno_E3_14_5 PF04834.12 GAP85993.1 - 0.66 10.5 0.0 0.66 10.5 0.0 2.4 2 1 0 2 2 2 0 Early E3 14.5 kDa protein DUF373 PF04123.13 GAP85993.1 - 8.4 5.7 8.3 15 4.9 8.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) PQ-loop PF04193.14 GAP85996.1 - 4.3e-19 68.0 8.4 1.3e-12 47.3 0.9 2.7 2 0 0 2 2 2 2 PQ loop repeat Phage_holin_3_6 PF07332.11 GAP85996.1 - 0.011 15.8 1.5 0.011 15.8 1.5 3.4 2 1 2 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3040 PF11239.8 GAP85996.1 - 0.25 11.6 3.9 0.16 12.2 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Vps55 PF04133.14 GAP85996.1 - 3.1 7.8 11.5 12 5.9 4.2 3.0 3 1 0 3 3 3 0 Vacuolar protein sorting 55 PAN_1 PF00024.26 GAP85997.1 - 3.9e-08 33.1 3.2 0.0029 17.5 1.0 2.3 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 GAP85997.1 - 0.0004 20.2 2.6 0.012 15.5 0.1 2.4 2 0 0 2 2 2 2 PAN domain MANEC PF07502.14 GAP85997.1 - 0.1 12.9 1.0 0.9 9.8 0.0 2.2 2 0 0 2 2 2 0 MANEC domain R3H-assoc PF13902.6 GAP85998.1 - 7.4e-09 36.1 0.9 1.6e-08 35.0 0.9 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain Fungal_trans PF04082.18 GAP85999.1 - 5.1e-12 45.4 0.1 3e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP85999.1 - 1.6e-08 34.5 8.2 3.1e-08 33.6 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 GAP86000.1 - 5.8e-12 45.6 0.1 9.4e-10 38.3 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAP86000.1 - 2.3e-08 33.4 0.2 4.9e-07 29.0 0.1 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAP86000.1 - 2.9e-08 33.2 0.2 6.2e-05 22.2 0.1 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.13 GAP86000.1 - 3e-08 33.5 0.3 4.7e-08 32.9 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 GAP86000.1 - 1.4e-07 31.3 0.2 1.1e-05 25.0 0.1 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAP86000.1 - 2.6e-07 30.7 0.4 5.9e-07 29.5 0.2 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAP86000.1 - 3.7e-07 30.5 0.2 6.5e-07 29.7 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 GAP86000.1 - 0.00013 21.3 0.1 0.0068 15.6 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein TrkA_N PF02254.18 GAP86000.1 - 0.0011 19.2 0.1 0.0034 17.6 0.2 1.8 2 0 0 2 2 2 1 TrkA-N domain Polysacc_synt_2 PF02719.15 GAP86000.1 - 0.0015 17.7 0.1 0.0029 16.8 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAP86000.1 - 0.0034 17.3 0.1 0.0056 16.6 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 GAP86000.1 - 0.005 16.3 0.1 0.0079 15.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 GAP86000.1 - 0.034 14.6 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HTH_13 PF11972.8 GAP86000.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain Chitin_synth_1 PF01644.17 GAP86001.1 - 9.9e-77 256.5 0.1 1.5e-76 255.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 GAP86001.1 - 1.1e-27 95.8 0.3 2.1e-27 94.9 0.3 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 GAP86001.1 - 5.3e-22 78.1 9.7 7.6e-22 77.6 0.1 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAP86001.1 - 1.4e-06 28.4 1.7 1.6e-05 24.9 2.6 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Polysacc_deac_1 PF01522.21 GAP86002.1 - 4e-24 84.9 0.0 6.6e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase GGDEF_2 PF17853.1 GAP86002.1 - 0.046 14.0 0.0 1.4 9.2 0.0 2.7 2 1 1 3 3 3 0 GGDEF-like domain Polysacc_deac_2 PF04748.13 GAP86002.1 - 0.053 12.7 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase HoxA13_N PF12284.8 GAP86002.1 - 0.23 12.1 0.0 0.35 11.5 0.0 1.2 1 0 0 1 1 1 0 Hox protein A13 N terminal WD40 PF00400.32 GAP86004.1 - 2.2e-14 53.6 11.0 0.0065 17.3 0.2 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP86004.1 - 4.7e-07 30.0 0.5 0.003 17.8 0.2 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP86004.1 - 1.8e-06 26.9 1.5 2.6e-05 23.1 0.4 2.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAP86004.1 - 0.0078 15.0 0.0 5.1 5.7 0.0 3.0 2 1 1 3 3 3 2 Nup133 N terminal like HA2 PF04408.23 GAP86005.1 - 2.1e-21 76.2 0.0 2.1e-21 76.2 0.0 3.1 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAP86005.1 - 2.4e-17 63.1 0.0 1.3e-16 60.7 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAP86005.1 - 1.4e-12 48.0 0.0 3.7e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAP86005.1 - 9.6e-09 35.2 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAP86005.1 - 2.2e-05 24.7 0.0 5.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 GAP86005.1 - 5.4e-05 22.6 0.0 5.4e-05 22.6 0.0 1.6 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 GAP86005.1 - 7.3e-05 22.6 0.5 0.00018 21.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAP86005.1 - 0.00041 20.7 0.0 0.00094 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 GAP86005.1 - 0.0016 18.1 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 GAP86005.1 - 0.0017 18.3 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SSE PF00437.20 GAP86005.1 - 0.0036 16.4 0.1 0.014 14.5 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase PF06745.13 GAP86005.1 - 0.0046 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 KaiC ResIII PF04851.15 GAP86005.1 - 0.005 16.9 1.0 1.1 9.3 0.0 2.7 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 GAP86005.1 - 0.037 14.1 0.2 0.27 11.3 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAP86005.1 - 0.058 13.6 1.4 0.36 11.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAP86005.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 GAP86005.1 - 0.1 13.1 0.7 0.32 11.5 0.0 2.2 3 0 0 3 3 1 0 ABC transporter AAA_23 PF13476.6 GAP86005.1 - 0.98 9.9 6.1 1.6 9.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain Acylphosphatase PF00708.18 GAP86006.1 - 9.6e-24 83.6 0.1 1.1e-23 83.5 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase TrpBP PF02081.15 GAP86006.1 - 0.093 12.6 0.2 1.1 9.2 0.0 2.2 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein DUF3539 PF12058.8 GAP86006.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) Hep_59 PF07052.11 GAP86007.1 - 4e-14 53.2 1.8 1.8e-13 51.1 0.1 3.0 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 VanY PF02557.17 GAP86007.1 - 0.027 14.3 0.3 0.044 13.6 0.3 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Pyrid_oxidase_2 PF13883.6 GAP86007.1 - 0.039 13.9 0.1 0.21 11.6 0.1 2.0 1 1 1 2 2 2 0 Pyridoxamine 5'-phosphate oxidase NinF PF05810.12 GAP86008.1 - 0.52 10.2 4.9 1.2 9.0 4.9 1.5 1 0 0 1 1 1 0 NinF protein C1_2 PF03107.16 GAP86008.1 - 1.9 8.9 10.9 0.4 11.0 7.1 1.9 2 0 0 2 2 2 0 C1 domain zf-RING_5 PF14634.6 GAP86008.1 - 5.2 7.1 13.7 14 5.8 4.1 2.6 1 1 1 2 2 2 0 zinc-RING finger domain Sulfotransfer_4 PF17784.1 GAP86009.1 - 4.5e-59 199.9 0.0 5.7e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAP86009.1 - 8.2e-08 32.9 0.9 1.8e-05 25.3 0.9 2.3 1 1 0 1 1 1 1 Sulfotransferase family Lactamase_B_3 PF13483.6 GAP86010.1 - 1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 GAP86010.1 - 0.00017 21.2 0.2 0.00028 20.5 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain EF-hand_1 PF00036.32 GAP86011.1 - 1.3e-26 90.1 7.1 9.2e-07 28.0 0.1 5.3 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 GAP86011.1 - 1.3e-22 80.0 6.6 1.6e-10 41.2 0.0 3.8 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GAP86011.1 - 1.9e-22 77.2 6.6 0.00027 20.6 0.1 5.2 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 GAP86011.1 - 3e-19 68.6 12.1 2.3e-09 37.0 0.1 5.1 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 GAP86011.1 - 4.6e-18 63.8 5.2 8.2e-05 21.9 0.2 4.4 4 0 0 4 4 4 4 EF hand GUN4 PF05419.12 GAP86011.1 - 0.084 13.0 0.0 0.18 11.9 0.0 1.5 2 0 0 2 2 2 0 GUN4-like EF-hand_4 PF12763.7 GAP86011.1 - 0.29 11.1 2.3 2.5 8.1 0.0 2.8 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Ank_2 PF12796.7 GAP86012.1 - 4.6e-92 302.7 1.3 1.4e-16 60.8 0.3 11.5 5 3 5 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP86012.1 - 2e-72 238.7 24.8 7.3e-10 39.2 0.2 15.8 12 5 4 16 16 16 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP86012.1 - 1.7e-65 209.1 23.6 4.7e-05 23.5 0.0 20.0 21 0 0 21 21 21 12 Ankyrin repeat Ank PF00023.30 GAP86012.1 - 5.9e-65 213.1 45.9 4.8e-05 23.6 0.0 21.0 22 0 0 22 22 22 14 Ankyrin repeat Ank_5 PF13857.6 GAP86012.1 - 9.1e-63 207.5 18.8 1.1e-10 41.6 0.0 12.9 11 2 2 13 13 13 9 Ankyrin repeats (many copies) NACHT PF05729.12 GAP86012.1 - 0.00075 19.5 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Imm49 PF15575.6 GAP86012.1 - 0.35 10.6 2.3 16 5.2 0.1 4.1 5 1 1 6 6 6 0 Immunity protein 49 HeLo PF14479.6 GAP86013.1 - 0.088 12.6 4.8 0.7 9.7 0.6 2.3 1 1 1 2 2 2 0 Prion-inhibition and propagation HeLo PF14479.6 GAP86014.1 - 4.1e-39 134.5 0.0 6.1e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation ChaC PF04752.12 GAP86014.1 - 7.4e-23 81.5 1.2 2e-12 47.5 1.8 2.4 1 1 1 2 2 2 2 ChaC-like protein PKS_DE PF18369.1 GAP86014.1 - 1.1 9.9 0.0 1.1 9.9 0.0 2.9 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain RRM_1 PF00076.22 GAP86015.1 - 2.5e-22 78.4 0.0 3.5e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAP86015.1 - 0.0031 17.6 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 GAP86015.1 - 0.18 11.6 0.0 0.32 10.9 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif HpcH_HpaI PF03328.14 GAP86017.1 - 2e-37 128.5 0.0 3e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 GAP86017.1 - 1.9e-10 40.4 0.0 2.2e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Herpes_pp85 PF04637.12 GAP86017.1 - 0.88 7.9 2.4 1.2 7.5 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Pkinase PF00069.25 GAP86018.1 - 4.2e-54 183.7 0.0 5.6e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86018.1 - 3.4e-31 108.5 0.0 4.2e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP86018.1 - 0.00027 20.3 0.0 0.0095 15.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAP86018.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 GAP86018.1 - 0.0047 16.6 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 GAP86018.1 - 0.005 15.9 0.1 0.0086 15.1 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 GAP86018.1 - 0.0081 15.1 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 GAP86018.1 - 0.019 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 GAP86018.1 - 0.025 14.5 0.0 0.07 13.0 0.0 1.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAP86018.1 - 0.028 13.2 0.0 0.041 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 GAP86020.1 - 3e-52 177.6 0.0 4e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86020.1 - 1.5e-24 86.7 0.0 4.4e-24 85.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 GAP86020.1 - 0.04 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 GAP86020.1 - 0.059 12.3 0.0 0.088 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ESR1_C PF12743.7 GAP86020.1 - 0.17 11.7 2.6 0.36 10.6 2.6 1.5 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal TMA7 PF09072.10 GAP86021.1 - 2.1e-28 98.9 16.9 2.3e-28 98.8 16.9 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 HlyIII PF03006.20 GAP86022.1 - 4.8e-64 216.1 7.7 5.8e-64 215.9 7.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related WD40 PF00400.32 GAP86023.1 - 0.00041 21.1 4.1 0.16 12.9 0.2 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Ank_2 PF12796.7 GAP86024.1 - 2.2e-32 111.5 0.0 1.7e-11 44.5 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 GAP86024.1 - 3.1e-22 78.0 1.9 1.2e-05 25.5 0.0 6.8 6 1 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 GAP86024.1 - 1e-20 73.8 0.2 1.6e-07 31.7 0.0 5.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP86024.1 - 2.3e-20 70.5 1.1 0.00015 21.9 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 GAP86024.1 - 1.5e-17 63.4 0.6 1.1e-07 32.0 0.0 4.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) SpoU_sub_bind PF08032.12 GAP86024.1 - 0.16 12.3 0.0 1.1 9.6 0.0 2.3 2 1 1 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding TPP_enzyme_N PF02776.18 GAP86025.1 - 8.7e-54 181.7 0.1 1.9e-52 177.4 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAP86025.1 - 8e-50 168.6 0.0 2.6e-48 163.7 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAP86025.1 - 7.2e-42 142.4 0.7 2.1e-41 140.9 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 GAP86025.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GalKase_gal_bdg PF10509.9 GAP86026.1 - 2.7e-20 71.6 0.0 4.8e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 GAP86026.1 - 3.3e-14 53.0 0.0 1e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 GAP86026.1 - 6.7e-13 48.7 3.7 1.7e-12 47.3 3.7 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain HTH_31 PF13560.6 GAP86026.1 - 0.062 13.6 0.1 1.1 9.6 0.0 2.8 1 1 1 2 2 2 0 Helix-turn-helix domain Sigma70_r3 PF04539.16 GAP86026.1 - 0.08 13.0 0.1 0.38 10.9 0.1 2.1 1 1 1 2 2 2 0 Sigma-70 region 3 HTH_3 PF01381.22 GAP86026.1 - 0.16 12.1 0.0 37 4.5 0.0 3.6 3 1 1 4 4 4 0 Helix-turn-helix DPBB_1 PF03330.18 GAP86028.1 - 2.6e-05 24.4 0.5 0.00013 22.1 0.1 2.3 2 1 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 GAP86028.1 - 0.00029 20.8 0.8 0.00062 19.7 0.8 1.5 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.17 GAP86028.1 - 0.00042 20.2 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 GAP86028.1 - 0.00053 20.1 0.9 0.001 19.2 0.4 1.7 1 1 0 1 1 1 1 Cerato-platanin BNR PF02012.20 GAP86028.1 - 0.098 12.7 0.7 0.32 11.2 0.7 1.9 1 0 0 1 1 1 0 BNR/Asp-box repeat Annexin PF00191.20 GAP86030.1 - 1.4e-73 242.8 4.7 5.8e-20 71.1 0.0 4.1 4 0 0 4 4 4 4 Annexin ABC_tran PF00005.27 GAP86031.1 - 1.4e-44 152.0 0.0 4e-28 98.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAP86031.1 - 2.1e-34 119.5 24.8 5.3e-19 68.9 11.4 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 GAP86031.1 - 6.1e-10 38.9 0.7 0.00056 19.4 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAP86031.1 - 6.8e-06 26.4 0.1 0.075 13.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAP86031.1 - 3.2e-05 24.4 0.3 0.12 12.7 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 GAP86031.1 - 7.2e-05 22.8 0.1 0.092 12.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 GAP86031.1 - 0.00013 21.6 0.7 0.019 14.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 GAP86031.1 - 0.00013 21.6 0.2 0.035 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAP86031.1 - 0.0002 21.3 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 GAP86031.1 - 0.00066 19.6 0.0 16 5.2 0.0 4.1 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAP86031.1 - 0.00086 19.9 1.1 0.21 12.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 GAP86031.1 - 0.0012 18.4 0.1 0.063 12.9 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 GAP86031.1 - 0.0018 18.4 1.6 0.014 15.5 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Zeta_toxin PF06414.12 GAP86031.1 - 0.0028 17.0 0.4 2.4 7.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.23 GAP86031.1 - 0.0088 16.1 0.0 0.65 10.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 GAP86031.1 - 0.022 13.8 1.0 4.2 6.3 0.2 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 GAP86031.1 - 0.036 13.6 0.2 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 GAP86031.1 - 0.047 12.9 1.2 6.7 5.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 GAP86031.1 - 0.053 13.7 0.0 8.5 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAP86031.1 - 0.069 12.9 0.4 14 5.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAP86031.1 - 0.12 12.4 0.2 13 5.8 0.1 2.6 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 GAP86031.1 - 0.12 12.1 0.4 2.9 7.6 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 GAP86031.1 - 0.13 12.6 0.1 27 5.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 GAP86031.1 - 0.15 11.3 0.3 2 7.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zn-ribbon_8 PF09723.10 GAP86032.1 - 0.96 9.6 3.9 2.6 8.2 0.2 2.7 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.26 GAP86032.1 - 6.4 7.4 5.1 52 4.6 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type HOOK PF05622.12 GAP86033.1 - 0.039 12.1 2.7 0.056 11.6 2.7 1.1 1 0 0 1 1 1 0 HOOK protein HLH PF00010.26 GAP86033.1 - 1.7 8.7 8.2 1.4 9.0 0.2 3.6 4 0 0 4 4 4 0 Helix-loop-helix DNA-binding domain DHR10 PF18595.1 GAP86033.1 - 2.9 8.0 7.5 8.3 6.5 7.5 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain PCI PF01399.27 GAP86034.1 - 2.2e-14 53.8 0.8 6.4e-14 52.3 0.4 2.1 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 GAP86034.1 - 3.6e-09 36.2 1.2 7.4e-09 35.2 1.2 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix DUF1451 PF07295.11 GAP86034.1 - 0.00017 21.7 0.7 0.33 11.0 0.0 2.7 2 0 0 2 2 2 2 Zinc-ribbon containing domain Remorin_C PF03763.13 GAP86034.1 - 0.16 11.9 2.2 1.1 9.2 0.1 2.8 3 0 0 3 3 3 0 Remorin, C-terminal region Rrf2 PF02082.20 GAP86034.1 - 0.18 12.2 0.2 2.6 8.4 0.1 2.8 4 0 0 4 4 4 0 Transcriptional regulator ADK PF00406.22 GAP86035.1 - 4.3e-42 143.7 0.1 7.2e-23 81.4 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 GAP86035.1 - 2.8e-31 108.7 0.2 6.7e-30 104.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAP86035.1 - 4.6e-06 27.2 0.0 1e-05 26.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAP86035.1 - 4.4e-05 23.7 0.8 0.00012 22.2 0.8 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 GAP86035.1 - 0.0025 17.5 0.1 0.0063 16.2 0.1 1.6 1 1 0 1 1 1 1 Thymidylate kinase Ploopntkinase3 PF18751.1 GAP86035.1 - 0.093 12.6 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 Dicty_REP PF05086.12 GAP86035.1 - 0.1 10.6 0.4 0.11 10.4 0.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MARVEL PF01284.23 GAP86036.1 - 3.7 7.6 11.8 5.6 7.0 10.1 2.1 1 1 1 2 2 2 0 Membrane-associating domain DUF5102 PF17104.5 GAP86037.1 - 2.3e-107 359.3 1.6 5e-107 358.2 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Nsp1_C PF05064.13 GAP86038.1 - 2.7e-39 133.6 2.9 5.8e-39 132.5 2.9 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 GAP86038.1 - 5.7e-11 43.1 160.4 0.00069 20.4 17.9 8.1 1 1 4 5 5 5 3 Nucleoporin FG repeat region SLATT_fungal PF18142.1 GAP86038.1 - 0.015 15.3 0.2 0.049 13.6 0.1 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Nup88 PF10168.9 GAP86038.1 - 0.031 12.1 1.9 0.042 11.7 1.9 1.2 1 0 0 1 1 1 0 Nuclear pore component RepB PF07506.11 GAP86038.1 - 0.13 12.3 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 RepB plasmid partitioning protein V-SNARE PF05008.15 GAP86038.1 - 0.36 11.2 7.4 0.92 9.9 0.3 3.2 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Mod_r PF07200.13 GAP86038.1 - 1 9.4 5.1 8 6.6 0.0 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4200 PF13863.6 GAP86038.1 - 1.7 9.0 6.0 6 7.3 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) 14-3-3 PF00244.20 GAP86039.1 - 5.9e-107 356.2 3.5 6.8e-107 356.0 3.5 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 GAP86039.1 - 0.12 12.7 1.5 0.26 11.6 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAP86039.1 - 0.51 10.9 3.9 0.74 10.4 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CSL PF05207.13 GAP86040.1 - 7.3e-18 64.1 0.2 1.2e-17 63.4 0.2 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 GAP86040.1 - 4.2e-12 46.0 0.8 5.6e-07 29.6 0.2 2.4 2 0 0 2 2 2 2 DnaJ domain SRP_TPR_like PF17004.5 GAP86040.1 - 0.0048 16.9 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Putative TPR-like repeat Mitoc_mL59 PF18126.1 GAP86041.1 - 1.5e-45 154.7 0.9 1.7e-45 154.5 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 DEAD PF00270.29 GAP86042.1 - 1.3e-47 161.8 0.0 3.4e-47 160.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP86042.1 - 7.8e-28 97.0 0.1 5.9e-27 94.2 0.2 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP86042.1 - 0.00056 20.0 0.0 0.0018 18.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 GAP86042.1 - 0.01 14.6 0.0 0.019 13.7 0.0 1.5 2 0 0 2 2 2 0 SNF2 family N-terminal domain PRAI PF00697.22 GAP86042.1 - 0.017 14.9 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Glyco_transf_15 PF01793.16 GAP86042.1 - 0.028 13.7 1.5 0.03 13.6 0.4 1.5 1 1 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF3334 PF11813.8 GAP86042.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) CMS1 PF14617.6 GAP86042.1 - 0.35 10.2 0.0 0.35 10.2 0.0 2.6 3 1 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit ERAP1_C PF11838.8 GAP86043.1 - 1.5e-87 294.1 0.0 6.8e-87 291.9 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 GAP86043.1 - 2e-84 282.6 0.2 3.7e-84 281.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 GAP86043.1 - 1.3e-50 172.2 0.7 2.1e-50 171.5 0.7 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Enolase_C PF00113.22 GAP86044.1 - 1.5e-151 503.7 0.2 2e-151 503.3 0.2 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 GAP86044.1 - 3.5e-57 192.2 0.2 6.8e-57 191.3 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 GAP86044.1 - 9.9e-06 25.3 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 GAP86044.1 - 0.0013 17.9 0.7 0.11 11.6 0.2 2.9 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus Ribosomal_S13_N PF08069.12 GAP86045.1 - 4.2e-29 100.4 0.4 7.6e-29 99.5 0.4 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 GAP86045.1 - 3e-15 56.2 0.2 4.9e-15 55.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 GAP86045.1 - 0.03 14.3 0.1 0.074 13.0 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.13 GAP86046.1 - 2e-15 56.2 0.1 4.7e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 Dpy-30 motif VRR_NUC PF08774.11 GAP86047.1 - 7.7e-23 80.6 0.0 1.9e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain CBFB_NFYA PF02045.15 GAP86050.1 - 3.2e-28 98.1 4.6 9.7e-28 96.6 4.6 1.9 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B LSM PF01423.22 GAP86051.1 - 2.7e-19 68.6 0.6 3.3e-19 68.3 0.6 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 GAP86051.1 - 0.0087 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Hfq protein DUF1461 PF07314.11 GAP86051.1 - 0.035 14.0 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) SM-ATX PF14438.6 GAP86051.1 - 0.038 14.1 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 GAP86051.1 - 0.069 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain DRMBL PF07522.14 GAP86052.1 - 1.8e-30 105.4 0.0 3.4e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 GAP86052.1 - 2.8e-06 27.0 0.1 9e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain zf-Di19 PF05605.12 GAP86052.1 - 0.016 15.5 1.0 0.065 13.5 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RNF220 PF15926.5 GAP86052.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 FliE PF02049.18 GAP86052.1 - 0.11 12.6 0.2 0.34 11.1 0.2 1.8 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Sugar_tr PF00083.24 GAP86053.1 - 2e-24 86.3 19.3 3.2e-22 79.0 19.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter AP_endonuc_2 PF01261.24 GAP86054.1 - 5.5e-29 101.1 0.1 8.2e-29 100.6 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.12 GAP86055.1 - 2.9e-42 143.6 0.6 5.7e-42 142.6 0.6 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 GAP86055.1 - 5.9e-09 36.0 0.0 2.2e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 GAP86055.1 - 6.1e-06 25.8 0.0 7.8e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86055.1 - 0.011 15.0 0.0 0.12 11.6 0.0 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.6 GAP86055.1 - 0.088 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Mad3_BUB1_I_2 PF17014.5 GAP86055.1 - 0.23 11.6 0.0 0.51 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein TENA_THI-4 PF03070.16 GAP86056.1 - 0.0018 18.1 0.0 0.037 13.8 0.0 2.3 2 0 0 2 2 2 2 TENA/THI-4/PQQC family RRM_1 PF00076.22 GAP86057.1 - 4.6e-23 80.8 0.1 1e-10 41.3 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAP86057.1 - 0.01 15.7 0.1 15 5.5 0.0 3.5 3 1 0 3 3 3 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GAP86057.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif OGG_N PF07934.12 GAP86058.1 - 2.5e-36 124.4 0.1 4.6e-36 123.6 0.1 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 GAP86058.1 - 1.3e-15 57.7 0.0 2.2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAP86058.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif zf-C2H2 PF00096.26 GAP86059.1 - 4.7e-09 36.2 14.9 2.1e-05 24.7 4.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP86059.1 - 1.3e-07 31.7 20.5 2.1e-05 24.7 2.1 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP86059.1 - 3.4e-06 27.4 14.1 0.0012 19.5 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 GAP86059.1 - 5.8e-06 26.5 1.3 1.7e-05 25.0 1.3 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 GAP86059.1 - 0.00011 22.1 2.4 0.00011 22.1 2.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP86059.1 - 0.00052 20.2 4.2 0.00071 19.8 1.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAP86059.1 - 0.051 13.9 1.1 0.051 13.9 1.1 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CCAP PF11105.8 GAP86059.1 - 0.064 13.2 0.7 0.11 12.4 0.7 1.3 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a zf-C2HC_2 PF13913.6 GAP86059.1 - 0.43 10.5 4.5 12 6.0 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 GAP86059.1 - 0.55 10.0 10.9 3.1 7.6 2.7 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type SF3b1 PF08920.10 GAP86061.1 - 2.5e-17 63.5 1.3 2.5e-17 63.5 1.3 2.5 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 GAP86061.1 - 9.6e-11 42.0 2.8 0.052 14.1 0.0 6.9 8 0 0 8 8 7 2 HEAT-like repeat HEAT_2 PF13646.6 GAP86061.1 - 1.3e-10 41.5 5.6 0.23 11.9 0.0 7.7 6 2 3 9 9 9 2 HEAT repeats HEAT PF02985.22 GAP86061.1 - 7.3e-09 35.1 6.8 0.45 10.9 0.1 9.0 11 0 0 11 11 10 1 HEAT repeat Cnd1 PF12717.7 GAP86061.1 - 6.9e-06 26.2 0.2 1.2 9.1 0.0 5.9 5 2 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GAP86061.1 - 0.00031 21.3 0.1 4.3 8.0 0.0 5.1 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 GAP86061.1 - 0.00064 19.7 0.8 0.14 12.1 0.0 4.6 5 2 0 6 6 6 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 GAP86061.1 - 0.00068 19.4 0.6 1.1 8.9 0.0 4.4 4 1 1 5 5 5 1 NUC173 domain Adaptin_N PF01602.20 GAP86061.1 - 0.0023 16.6 0.1 1.1 7.7 0.0 3.1 3 1 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 GAP86061.1 - 0.0026 17.4 0.1 0.91 9.0 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal UNC45-central PF11701.8 GAP86061.1 - 0.0038 17.2 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central DRIM PF07539.12 GAP86061.1 - 0.091 11.1 0.1 11 4.1 0.0 3.4 2 1 3 5 5 5 0 Down-regulated in metastasis Opi1 PF08618.10 GAP86061.1 - 0.12 11.6 5.1 0.26 10.5 5.1 1.5 1 0 0 1 1 1 0 Transcription factor Opi1 Rax2 PF12768.7 GAP86062.1 - 3.8e-71 239.0 0.0 3.3e-70 235.9 0.0 2.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DUF5122 PF17164.4 GAP86062.1 - 0.0048 17.2 12.3 5.6 7.4 0.2 6.6 6 0 0 6 6 6 3 Domain of unknown function (DUF5122) beta-propeller SNase PF00565.17 GAP86063.1 - 2e-25 89.3 0.0 2.7e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue PKD_channel PF08016.12 GAP86064.1 - 0.0015 17.3 7.4 0.061 12.0 0.9 2.2 2 0 0 2 2 2 2 Polycystin cation channel M157 PF11624.8 GAP86064.1 - 0.14 11.5 0.3 0.23 10.8 0.3 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 MTS PF05175.14 GAP86065.1 - 0.00077 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain LSM PF01423.22 GAP86066.1 - 6.4e-18 64.2 0.1 8.3e-18 63.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAP86066.1 - 0.003 17.6 0.1 0.0045 17.1 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.11 GAP86066.1 - 2.4 6.9 5.1 3 6.5 5.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ribosomal_S8e PF01201.22 GAP86067.1 - 1.4e-42 145.1 1.0 2e-42 144.6 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Pkr1 PF08636.10 GAP86068.1 - 3.1e-29 100.9 6.9 4e-29 100.6 6.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 OAD_gamma PF04277.13 GAP86068.1 - 0.39 11.3 4.6 2.5 8.8 4.6 2.5 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Spt5_N PF11942.8 GAP86069.1 - 3.8 8.5 9.8 1.9 9.5 7.5 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal F-box_4 PF15966.5 GAP86070.1 - 0.0015 18.4 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 F-box F-box PF00646.33 GAP86070.1 - 0.002 17.9 0.5 0.015 15.2 0.0 2.7 3 0 0 3 3 3 1 F-box domain F-box-like_2 PF13013.6 GAP86070.1 - 0.13 12.2 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain Ysc84 PF04366.12 GAP86071.1 - 1.8e-31 108.5 0.0 2.9e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Cwf_Cwc_15 PF04889.12 GAP86071.1 - 7.1 6.3 8.2 15 5.2 8.2 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Actin PF00022.19 GAP86072.1 - 2.2e-16 59.5 0.0 1.6e-13 50.0 0.0 2.5 3 0 0 3 3 3 2 Actin GEMIN8 PF15348.6 GAP86072.1 - 1.1 9.6 7.6 0.85 9.9 0.1 2.4 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 ADH_zinc_N PF00107.26 GAP86073.1 - 2e-26 92.5 0.3 4.6e-26 91.3 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP86073.1 - 2.4e-19 70.7 0.1 6.1e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP86073.1 - 8.1e-06 25.7 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cpn60_TCP1 PF00118.24 GAP86074.1 - 1.6e-147 492.1 17.6 1.8e-147 491.9 17.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.6 GAP86074.1 - 0.08 12.9 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) Cas_GSU0054 PF09609.10 GAP86075.1 - 0.086 11.5 0.7 0.18 10.5 0.6 1.5 2 0 0 2 2 2 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) AAA PF00004.29 GAP86076.1 - 3.1e-40 137.7 0.0 5.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAP86076.1 - 7.4e-07 28.9 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAP86076.1 - 7.4e-05 22.8 0.1 0.00062 19.8 0.0 2.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP86076.1 - 0.00013 22.2 0.0 0.0055 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 GAP86076.1 - 0.00042 20.5 0.0 0.0016 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAP86076.1 - 0.00068 20.1 0.1 0.014 15.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 GAP86076.1 - 0.0015 17.7 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 GAP86076.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 GAP86076.1 - 0.022 15.0 0.0 0.063 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAP86076.1 - 0.033 13.7 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 GAP86076.1 - 0.049 13.8 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAP86076.1 - 0.057 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 GAP86076.1 - 0.08 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAP86076.1 - 0.081 12.6 0.1 0.28 10.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAP86076.1 - 0.082 12.6 0.1 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAP86076.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GAP86076.1 - 0.11 12.2 0.4 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAP86076.1 - 0.14 12.7 0.0 0.5 10.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 GAP86076.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Dicty_REP PF05086.12 GAP86077.1 - 0.39 8.7 0.3 0.44 8.5 0.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 GAP86077.1 - 0.47 8.5 1.9 0.61 8.2 1.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus IBR PF01485.21 GAP86077.1 - 8.5 6.7 10.7 1 9.6 5.2 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain RRM_1 PF00076.22 GAP86078.1 - 1.4e-11 44.1 0.1 2.5e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.9 GAP86078.1 - 0.14 11.7 7.9 0.21 11.2 7.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein STIMATE PF12400.8 GAP86079.1 - 2.2e-41 141.3 4.9 2.2e-41 141.3 4.9 1.6 2 0 0 2 2 2 1 STIMATE family Corona_S2 PF01601.16 GAP86080.1 - 8.1 4.8 16.3 11 4.4 16.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF4048 PF13257.6 GAP86081.1 - 0.063 13.1 0.3 0.063 13.1 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4048) RCR PF12273.8 GAP86082.1 - 2.2e-20 73.5 10.1 2.9e-20 73.1 10.1 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 GAP86082.1 - 0.00032 20.5 0.3 0.00039 20.2 0.3 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF2207 PF09972.9 GAP86082.1 - 0.11 11.2 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3328 PF11807.8 GAP86082.1 - 0.16 11.7 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Arf PF00025.21 GAP86083.1 - 1.9e-42 144.7 0.0 2.1e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAP86083.1 - 3.5e-18 65.7 0.0 3.9e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP86083.1 - 4.3e-14 52.8 0.0 7e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAP86083.1 - 4.9e-06 26.6 0.0 7.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAP86083.1 - 1.6e-05 24.4 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAP86083.1 - 1.7e-05 24.3 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAP86083.1 - 0.00012 21.4 0.3 0.00028 20.2 0.1 2.0 2 1 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 GAP86083.1 - 0.0045 16.5 0.0 0.015 14.9 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 GAP86083.1 - 0.0094 15.5 0.3 0.023 14.2 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 GAP86083.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RNA_pol_Rpb2_6 PF00562.28 GAP86084.1 - 2e-115 386.0 0.1 2.6e-115 385.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 GAP86084.1 - 7e-31 107.3 0.0 1.1e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 GAP86084.1 - 1.2e-28 99.0 0.0 2.7e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 GAP86084.1 - 5.2e-24 84.0 0.0 1.1e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 GAP86084.1 - 3.1e-23 82.4 0.0 5.4e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 GAP86084.1 - 1.1e-15 57.8 0.0 3e-14 53.2 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 zinc_ribbon_15 PF17032.5 GAP86084.1 - 0.14 13.0 0.1 0.29 11.9 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon family Tyrosinase PF00264.20 GAP86085.1 - 1.4e-47 162.9 2.3 1.4e-47 162.9 2.3 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 GAP86085.1 - 4.5e-16 59.6 0.0 8.9e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain Glyco_hydro_61 PF03443.14 GAP86086.1 - 1.8e-38 132.6 0.0 2.4e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ammonium_transp PF00909.21 GAP86088.1 - 1.3e-116 389.6 29.4 1.5e-116 389.4 29.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DNA_pol_B_palm PF14792.6 GAP86089.1 - 1.7e-37 128.1 0.0 3.5e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 GAP86089.1 - 4.7e-22 77.6 0.0 9.3e-22 76.6 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 GAP86089.1 - 6.5e-19 68.1 0.5 6.4e-18 64.9 0.4 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.8 GAP86089.1 - 2.5e-05 24.4 0.0 0.063 13.5 0.0 2.5 2 0 0 2 2 2 2 Pathogenicity locus DNA_pol_B_thumb PF14791.6 GAP86089.1 - 3.1e-05 24.1 0.1 6.5e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb NTP_transf_2 PF01909.23 GAP86089.1 - 0.03 14.6 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain GMP_synt_C PF00958.22 GAP86090.1 - 1.4e-35 121.2 0.0 2.7e-35 120.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 GAP86090.1 - 2.6e-32 112.2 0.0 4.6e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 GAP86090.1 - 4.2e-08 32.6 0.0 1.1e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 GAP86090.1 - 0.0012 18.6 0.1 0.0045 16.8 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 GAP86090.1 - 0.0033 16.3 0.1 0.0073 15.1 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 GAP86090.1 - 0.0099 15.4 0.0 0.059 12.9 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 GAP86090.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 GAP86090.1 - 0.041 13.2 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Arginosuccinate synthase ThiI PF02568.14 GAP86090.1 - 0.083 12.5 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 GAP86090.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 PP-loop family sCache_like PF16736.5 GAP86090.1 - 0.2 11.8 0.1 0.51 10.5 0.1 1.6 1 0 0 1 1 1 0 Single Cache-like PhoD PF09423.10 GAP86091.1 - 3.7e-109 365.0 4.0 4.6e-109 364.6 4.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 GAP86091.1 - 2e-30 105.2 0.0 4.6e-30 104.0 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 GAP86091.1 - 5.4e-05 23.7 2.4 6.7e-05 23.4 0.1 2.4 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain PrmA PF06325.13 GAP86092.1 - 1.7e-10 40.8 0.3 3.2e-10 39.9 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAP86092.1 - 1.7e-09 38.3 0.0 6.2e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP86092.1 - 1e-08 35.2 0.5 2.2e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAP86092.1 - 4.3e-07 29.2 0.2 6.5e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 GAP86092.1 - 1.8e-06 28.5 0.0 7.9e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAP86092.1 - 4.3e-05 23.5 0.3 9.1e-05 22.4 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP86092.1 - 0.00011 22.1 0.0 0.00026 20.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PRMT5_C PF17286.2 GAP86092.1 - 0.0016 18.3 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain CMAS PF02353.20 GAP86092.1 - 0.002 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 GAP86092.1 - 0.0023 17.8 0.2 0.005 16.7 0.2 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.14 GAP86092.1 - 0.004 16.7 0.4 0.013 15.1 0.1 1.8 1 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAP86092.1 - 0.0063 17.2 0.0 0.015 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAP86092.1 - 0.055 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 GAP86092.1 - 0.096 11.7 0.1 0.7 8.9 0.1 2.1 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 GAP86092.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Lum_binding PF00677.17 GAP86093.1 - 9e-46 153.8 0.4 6.1e-22 77.4 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain DAGK_cat PF00781.24 GAP86093.1 - 0.078 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain ERCC4 PF02732.15 GAP86094.1 - 3.3e-25 89.1 0.1 5.2e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 GAP86094.1 - 0.00049 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 GAP86094.1 - 0.094 13.3 0.0 0.3 11.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain HTH_27 PF13463.6 GAP86094.1 - 0.12 12.9 0.2 0.64 10.5 0.0 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain PGM_PMM_I PF02878.16 GAP86095.1 - 4.1e-15 55.7 0.1 1.6e-06 27.9 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 GAP86095.1 - 2.1e-10 40.6 0.6 8e-10 38.8 0.5 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 GAP86095.1 - 0.00038 21.0 0.6 0.018 15.7 0.3 3.3 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 GAP86095.1 - 0.00057 20.1 0.2 0.0023 18.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III zf-trcl PF13451.6 GAP86096.1 - 0.002 18.0 0.3 0.0042 16.9 0.3 1.5 1 0 0 1 1 1 1 Probable zinc-ribbon domain NOB1_Zn_bind PF08772.11 GAP86096.1 - 0.04 14.1 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like TF_Zn_Ribbon PF08271.12 GAP86096.1 - 0.073 12.6 0.6 0.17 11.4 0.6 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding zinc-ribbons_6 PF07191.12 GAP86096.1 - 0.11 12.5 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbons Auto_anti-p27 PF06677.12 GAP86096.1 - 0.19 11.9 0.7 0.39 10.9 0.7 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Nudix_N_2 PF14803.6 GAP86096.1 - 2.3 8.2 6.5 7.8 6.5 0.4 3.3 3 0 0 3 3 3 0 Nudix N-terminal Ribonuc_L-PSP PF01042.21 GAP86098.1 - 6.1e-42 142.4 0.0 8.1e-42 142.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Nt_Gln_amidase PF09764.9 GAP86098.1 - 0.034 13.7 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 N-terminal glutamine amidase V-ATPase_H_C PF11698.8 GAP86098.1 - 0.11 12.6 0.1 0.15 12.2 0.1 1.1 1 0 0 1 1 1 0 V-ATPase subunit H L27 PF02828.16 GAP86099.1 - 0.083 12.7 0.1 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 L27 domain zf-H2C2_5 PF13909.6 GAP86101.1 - 0.2 11.5 10.4 0.094 12.5 2.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 GAP86101.1 - 0.63 10.6 14.7 0.12 12.9 4.2 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP86101.1 - 0.91 10.5 19.4 0.4 11.6 3.6 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Per1 PF04080.13 GAP86102.1 - 4.2e-104 347.8 8.9 5.1e-104 347.6 8.9 1.1 1 0 0 1 1 1 1 Per1-like family DUF3433 PF11915.8 GAP86103.1 - 7.2e-26 90.5 20.7 1.8e-15 57.2 1.9 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) SNF2_N PF00176.23 GAP86104.1 - 1.6e-62 211.2 0.0 2.4e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 GAP86104.1 - 1.6e-09 37.8 0.0 4e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAP86104.1 - 5.9e-08 32.9 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAP86104.1 - 0.0012 19.1 0.0 0.0043 17.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 GAP86104.1 - 0.024 14.6 7.9 0.051 13.5 7.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAP86104.1 - 0.049 13.8 3.8 0.11 12.6 3.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GAP86104.1 - 0.05 13.5 7.5 0.14 12.0 7.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP86104.1 - 0.2 12.0 7.9 0.56 10.6 7.9 1.9 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 GAP86104.1 - 0.9 9.4 5.4 2.4 8.1 5.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 NACHT PF05729.12 GAP86105.1 - 1.6e-06 28.1 0.0 4.8e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GAP86105.1 - 3.8e-05 24.1 0.0 0.00012 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP86105.1 - 0.00024 21.4 0.6 0.0011 19.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain zf-H2C2_2 PF13465.6 GAP86105.1 - 0.0026 18.1 0.7 0.0026 18.1 0.7 3.9 3 0 0 3 3 3 1 Zinc-finger double domain ResIII PF04851.15 GAP86105.1 - 0.0036 17.3 0.0 0.0097 15.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PI3K_P85_iSH2 PF16454.5 GAP86105.1 - 0.0064 16.1 0.7 0.014 15.0 0.7 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DZR PF12773.7 GAP86105.1 - 0.025 14.6 1.5 0.059 13.4 1.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF2075 PF09848.9 GAP86105.1 - 0.038 13.2 0.2 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 GAP86105.1 - 0.038 13.9 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 GAP86105.1 - 0.065 12.4 0.1 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 GAP86105.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4337 PF14235.6 GAP86105.1 - 0.17 12.0 0.5 0.39 10.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Endonuclease_7 PF02945.15 GAP86105.1 - 0.67 9.9 4.3 2.4 8.1 4.3 2.0 1 0 0 1 1 1 0 Recombination endonuclease VII zf-C2H2_4 PF13894.6 GAP86105.1 - 1.7 9.7 13.5 5.2 8.2 0.3 4.4 3 0 0 3 3 3 0 C2H2-type zinc finger HET PF06985.11 GAP86106.1 - 2.3e-24 86.4 0.0 4.5e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Melibiase_2 PF16499.5 GAP86106.1 - 0.0049 16.1 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A Thioredoxin_7 PF13899.6 GAP86107.1 - 2.1e-17 63.1 0.0 5.7e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 GAP86107.1 - 9.8e-08 32.1 0.0 3.1e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 GAP86107.1 - 4.8e-06 26.3 0.0 1.7e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain Thioredox_DsbH PF03190.15 GAP86107.1 - 0.053 13.5 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 UIM PF02809.20 GAP86107.1 - 5 7.3 8.1 0.39 10.7 1.6 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif MRC1 PF09444.10 GAP86107.1 - 6.4 7.3 13.6 0.73 10.3 8.1 2.0 2 0 0 2 2 2 0 MRC1-like domain Fungal_trans PF04082.18 GAP86108.1 - 2.6e-10 39.8 0.0 4.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP86108.1 - 3.5e-09 36.6 10.5 3.5e-09 36.6 10.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HIT PF01230.23 GAP86109.1 - 1e-20 74.3 0.0 1.4e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAP86109.1 - 0.0093 16.4 0.1 0.16 12.4 0.1 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.29 GAP86110.1 - 1.7e-11 44.7 0.0 3.1e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAP86110.1 - 2.3e-07 31.2 0.0 5.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAP86110.1 - 4.9e-05 23.3 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAP86110.1 - 8.1e-05 22.4 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 GAP86110.1 - 0.00011 22.2 0.0 0.0003 20.7 0.0 1.7 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_33 PF13671.6 GAP86110.1 - 0.00076 19.7 0.4 0.0024 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAP86110.1 - 0.002 17.9 0.1 0.0044 16.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP86110.1 - 0.003 18.0 0.0 0.0093 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 GAP86110.1 - 0.0032 17.5 0.0 0.0065 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAP86110.1 - 0.0051 17.4 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAP86110.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 GAP86110.1 - 0.018 15.0 0.1 0.076 12.9 0.0 2.2 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 GAP86110.1 - 0.055 14.0 0.1 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 GAP86110.1 - 0.079 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_2 PF07724.14 GAP86110.1 - 0.094 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 GAP86110.1 - 0.094 13.0 0.6 0.62 10.4 0.6 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAP86110.1 - 0.17 11.6 0.1 0.46 10.2 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein Aldedh PF00171.22 GAP86111.1 - 2.5e-143 477.9 1.4 2.8e-143 477.8 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4231 PF14015.6 GAP86112.1 - 0.094 13.2 1.2 0.19 12.2 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Peptidase_M56 PF05569.11 GAP86112.1 - 0.11 11.7 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 FAM209 PF15206.6 GAP86112.1 - 0.2 11.5 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 FAM209 family UPF0370 PF13980.6 GAP86112.1 - 1.1 9.4 2.5 1.8 8.7 2.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DUF917 PF06032.12 GAP86113.1 - 2.9e-123 411.1 1.3 5.4e-123 410.3 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 GAP86113.1 - 5.1e-32 111.3 6.6 1.9e-29 102.9 0.2 3.5 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAP86113.1 - 6.7e-28 97.6 0.2 2.2e-25 89.4 0.0 2.9 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 GAP86113.1 - 0.0021 16.8 2.9 0.0041 15.8 0.0 2.6 3 0 0 3 3 3 1 MutL protein StbA PF06406.11 GAP86113.1 - 0.013 14.8 0.2 3.6 6.7 0.0 2.5 2 0 0 2 2 2 0 StbA protein BcrAD_BadFG PF01869.20 GAP86113.1 - 0.026 14.0 1.4 0.99 8.8 0.1 2.8 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Ribosomal_L5_C PF00673.21 GAP86115.1 - 2.7e-22 78.7 0.0 3.9e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAP86115.1 - 3.3e-20 72.2 0.0 7.2e-20 71.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 GAP86116.1 - 6.7e-18 64.1 0.0 1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain CPSase_L_D2 PF02786.17 GAP86117.1 - 2.5e-81 272.2 0.2 3.9e-81 271.6 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 GAP86117.1 - 3e-69 232.8 0.0 5.2e-69 232.0 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 GAP86117.1 - 3.2e-38 130.7 0.0 6.6e-38 129.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAP86117.1 - 5.2e-32 110.1 0.0 1.5e-31 108.7 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 GAP86117.1 - 3.5e-25 89.1 0.0 6.2e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 GAP86117.1 - 5.2e-19 67.8 3.4 9.8e-19 67.0 1.7 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAP86117.1 - 2.3e-09 37.0 0.9 5.9e-06 26.0 0.0 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 GAP86117.1 - 3.5e-09 36.5 0.0 6.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 GAP86117.1 - 2.4e-07 30.5 0.0 4.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAP86117.1 - 5.9e-05 23.2 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 GAP86117.1 - 0.00054 19.6 0.0 0.002 17.8 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 GAP86117.1 - 0.0021 17.3 0.1 0.13 11.4 0.0 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 GAP86117.1 - 0.0023 17.6 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 GAP86117.1 - 0.0063 17.2 0.2 6.6 7.5 0.0 3.2 4 0 0 4 4 2 1 HlyD family secretion protein DUF2118 PF09891.9 GAP86117.1 - 0.028 14.4 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GARS_A PF01071.19 GAP86117.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.11 GAP86117.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.19 GAP86117.1 - 0.26 11.2 0.7 0.82 9.6 0.1 2.1 2 0 0 2 2 2 0 Glycine cleavage H-protein Clathrin PF00637.20 GAP86118.1 - 9.1e-198 648.1 31.2 3.5e-31 108.0 2.3 7.5 8 0 0 8 8 8 7 Region in Clathrin and VPS TPR_14 PF13428.6 GAP86118.1 - 2.2e-07 31.1 5.0 14 6.9 0.1 9.1 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAP86118.1 - 6.5e-06 25.8 8.1 4.8 7.4 0.0 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAP86118.1 - 0.00041 20.6 5.1 14 6.1 0.1 6.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP86118.1 - 0.0006 19.5 4.8 2.9 7.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 GAP86118.1 - 0.0025 16.9 0.4 1.9 7.4 0.0 2.5 2 0 0 2 2 2 2 Coatomer WD associated region Vps39_1 PF10366.9 GAP86118.1 - 0.0025 18.0 11.5 1.3 9.4 0.1 6.9 5 2 2 7 7 7 1 Vacuolar sorting protein 39 domain 1 TPR_8 PF13181.6 GAP86118.1 - 0.0088 16.2 7.1 0.75 10.2 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat VapB_antitoxin PF09957.9 GAP86118.1 - 0.048 13.6 0.2 0.57 10.1 0.0 2.8 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB TPR_10 PF13374.6 GAP86118.1 - 0.072 13.0 0.6 50 3.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAP86118.1 - 0.87 10.1 10.7 16 6.1 0.1 6.8 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAP86118.1 - 2.4 8.5 16.6 3.2 8.1 0.0 7.4 9 0 0 9 9 9 0 Tetratricopeptide repeat Clathrin_propel PF01394.20 GAP86119.1 - 1.5e-39 132.4 2.3 6.5e-07 29.4 0.1 6.3 6 0 0 6 6 6 6 Clathrin propeller repeat TetM_leader PF08076.11 GAP86119.1 - 0.27 11.0 1.7 0.51 10.2 0.2 2.0 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide DUF1746 PF08508.10 GAP86120.1 - 1.5e-41 141.4 1.0 2.1e-41 140.9 1.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC_insert PF05189.13 GAP86121.1 - 2e-31 108.5 0.0 3.7e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 GAP86121.1 - 5.8e-28 97.6 0.2 7.2e-28 97.3 0.2 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Sec66 PF09802.9 GAP86122.1 - 1.6e-79 265.7 0.2 1.9e-79 265.5 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Cast PF10174.9 GAP86122.1 - 0.00034 19.0 0.8 0.00042 18.7 0.8 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone RRM_1 PF00076.22 GAP86123.1 - 4.8e-12 45.5 0.0 2.2e-05 24.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF780 PF05611.11 GAP86123.1 - 0.011 16.5 3.4 0.011 16.5 3.4 2.3 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF780) GTP-bdg_M PF16360.5 GAP86123.1 - 0.017 15.7 0.4 0.017 15.7 0.4 1.7 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region RRM_occluded PF16842.5 GAP86123.1 - 0.05 13.5 0.0 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_7 PF16367.5 GAP86123.1 - 0.081 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif DUF3405 PF11885.8 GAP86124.1 - 1.1e-222 740.3 0.6 1.3e-222 740.0 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) GCV_T PF01571.21 GAP86126.1 - 8e-81 271.2 0.0 1e-80 270.8 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 GAP86126.1 - 4.6e-21 74.5 0.1 1.1e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Arf PF00025.21 GAP86127.1 - 2.6e-80 268.0 0.3 3e-80 267.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAP86127.1 - 1.7e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAP86127.1 - 2e-14 53.4 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAP86127.1 - 2.6e-13 49.9 1.5 2e-09 37.1 0.5 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GAP86127.1 - 3.4e-13 49.5 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAP86127.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAP86127.1 - 2.9e-06 27.3 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 GAP86127.1 - 0.0095 15.3 1.0 0.028 13.7 1.0 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase EMP24_GP25L PF01105.24 GAP86128.1 - 1.2e-45 155.7 0.0 1.4e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sulfate_transp PF00916.20 GAP86129.1 - 6.6e-50 169.9 16.7 1.2e-49 169.1 16.7 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 GAP86129.1 - 1.2e-14 54.2 0.0 2.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 GAP86129.1 - 2.9e-09 36.6 0.0 7.2e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.11 GAP86130.1 - 6.2e-11 42.7 0.0 9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 GAP86130.1 - 0.069 14.0 0.0 0.51 11.2 0.0 2.3 2 0 0 2 2 2 0 Flagellar protein FliT AICARFT_IMPCHas PF01808.18 GAP86131.1 - 2e-91 306.5 0.1 2.7e-91 306.1 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 GAP86131.1 - 4.5e-24 84.5 0.0 8.8e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain EF1_GNE PF00736.19 GAP86132.1 - 2e-28 98.4 0.3 3.2e-28 97.7 0.3 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 GAP86132.1 - 1.5e-14 54.1 6.9 1.5e-14 54.1 6.9 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 GAP86132.1 - 0.00026 21.1 0.6 0.0012 19.0 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAP86132.1 - 0.00055 20.1 0.1 0.0038 17.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP86132.1 - 0.2 11.7 1.0 2.2 8.4 1.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.14 GAP86133.1 - 2.3e-44 151.5 0.0 2.5e-43 148.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAP86133.1 - 4.2e-36 123.0 2.4 4.2e-36 123.0 2.4 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 GAP86133.1 - 8.7e-25 86.6 0.6 8.7e-25 86.6 0.6 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 GAP86133.1 - 1.4e-18 67.5 0.1 1.1e-09 38.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAP86133.1 - 5.3e-12 45.9 0.0 1.5e-08 34.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAP86133.1 - 5e-10 40.0 3.3 0.00057 20.3 0.4 4.1 2 2 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 GAP86133.1 - 4.3e-07 29.8 0.3 0.00017 21.3 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 GAP86133.1 - 1.7e-06 28.3 5.9 0.021 15.1 0.1 4.0 3 3 1 4 4 3 2 AAA domain NACHT PF05729.12 GAP86133.1 - 5e-06 26.5 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 GAP86133.1 - 5.1e-06 26.6 0.5 2.3 8.1 0.1 4.0 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 GAP86133.1 - 6.4e-05 22.4 0.1 0.013 14.9 0.1 3.4 3 1 0 3 3 2 1 Bacterial TniB protein AAA_7 PF12775.7 GAP86133.1 - 7.6e-05 22.3 0.0 0.34 10.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 GAP86133.1 - 0.00014 21.9 0.0 0.62 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 GAP86133.1 - 0.00077 19.2 0.1 1.8 8.3 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 GAP86133.1 - 0.0015 18.5 0.1 0.57 10.1 0.0 3.0 2 1 1 3 3 3 1 RsgA GTPase RNA_helicase PF00910.22 GAP86133.1 - 0.0018 18.6 0.0 0.38 11.1 0.0 2.9 2 1 0 2 2 2 1 RNA helicase ABC_tran PF00005.27 GAP86133.1 - 0.0022 18.5 2.1 0.75 10.3 0.0 3.4 3 0 0 3 3 3 1 ABC transporter SRP54 PF00448.22 GAP86133.1 - 0.0039 16.8 0.0 0.19 11.3 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 GAP86133.1 - 0.0047 17.2 0.3 7.5 6.8 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA_24 PF13479.6 GAP86133.1 - 0.0058 16.4 0.0 0.77 9.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAP86133.1 - 0.0059 16.3 0.1 0.46 10.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 GAP86133.1 - 0.0075 16.3 0.1 3.5 7.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 GAP86133.1 - 0.0075 16.8 4.6 0.11 13.0 0.0 3.3 4 0 0 4 4 2 1 AAA domain Roc PF08477.13 GAP86133.1 - 0.0078 16.4 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 GAP86133.1 - 0.0086 15.5 0.0 3.2 7.1 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 GAP86133.1 - 0.01 15.5 0.1 0.31 10.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 GAP86133.1 - 0.01 15.4 1.1 0.42 10.1 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 GAP86133.1 - 0.012 15.9 0.5 0.8 10.0 0.1 3.2 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 GAP86133.1 - 0.012 15.6 0.4 5.9 6.9 0.0 3.4 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit PhoH PF02562.16 GAP86133.1 - 0.023 14.2 0.1 0.9 9.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.13 GAP86133.1 - 0.024 13.8 0.2 1.2 8.2 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 GAP86133.1 - 0.037 13.3 0.0 1.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin PIF1 PF05970.14 GAP86133.1 - 0.073 12.2 0.0 1.6 7.8 0.0 2.4 3 0 0 3 3 2 0 PIF1-like helicase CENP-F_leu_zip PF10473.9 GAP86133.1 - 0.076 13.0 18.6 0.16 12.0 16.1 2.6 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_33 PF13671.6 GAP86133.1 - 0.077 13.1 0.0 19 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 GAP86133.1 - 0.088 12.5 0.1 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_6 PF12774.7 GAP86133.1 - 0.17 10.8 0.0 2 7.3 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Macoilin PF09726.9 GAP86133.1 - 0.26 9.8 4.6 0.39 9.2 4.6 1.1 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 GAP86133.1 - 0.32 11.1 10.4 0.62 10.1 10.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAUS2 PF15003.6 GAP86133.1 - 0.43 10.3 8.6 0.72 9.6 4.1 2.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 FAM76 PF16046.5 GAP86133.1 - 0.47 9.8 3.2 0.76 9.1 3.2 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1154 PF06631.11 GAP86133.1 - 0.81 9.8 5.5 15 5.7 5.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1154) DUF1640 PF07798.11 GAP86133.1 - 1.2 9.2 10.8 2.4 8.2 10.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_23 PF13476.6 GAP86133.1 - 3.1 8.2 22.1 2.4e+02 2.1 20.9 3.2 2 1 0 2 2 2 0 AAA domain OEP PF02321.18 GAP86133.1 - 6.3 6.6 10.3 15 5.3 10.3 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein TMCO5 PF14992.6 GAP86133.1 - 8.9 5.8 11.7 14 5.1 11.7 1.2 1 0 0 1 1 1 0 TMCO5 family DEAD PF00270.29 GAP86134.1 - 2e-29 102.6 0.0 3.4e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 GAP86134.1 - 8.3e-22 77.8 0.1 2.2e-21 76.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 GAP86134.1 - 4.9e-13 49.4 0.0 3.7e-12 46.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP86134.1 - 1.1e-05 25.5 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 GAP86134.1 - 8.6e-05 22.9 0.0 0.00025 21.4 0.0 1.7 1 1 0 1 1 1 1 DNA replication factor CDT1 like Ran_BP1 PF00638.18 GAP86135.1 - 5.4e-13 49.3 0.1 1.7e-05 25.0 0.1 2.5 2 0 0 2 2 2 2 RanBP1 domain WH1 PF00568.23 GAP86135.1 - 0.044 13.7 0.0 0.8 9.7 0.0 2.2 2 0 0 2 2 2 0 WH1 domain BSP_II PF05432.11 GAP86135.1 - 1.2 8.8 25.7 0.55 9.9 5.5 2.5 2 1 0 2 2 2 0 Bone sialoprotein II (BSP-II) Chitin_synth_2 PF03142.15 GAP86136.1 - 1.3e-23 83.4 4.9 5.9e-21 74.7 3.0 2.5 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 GAP86136.1 - 6.2e-18 65.4 5.4 6.2e-18 65.4 5.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAP86136.1 - 7e-13 49.0 0.0 1.8e-12 47.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAP86136.1 - 0.018 14.8 0.2 6.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 PH_3 PF14593.6 GAP86136.1 - 0.14 12.3 0.4 0.78 9.9 0.0 2.4 3 0 0 3 3 3 0 PH domain MIF4G PF02854.19 GAP86137.1 - 4e-53 180.2 0.0 1.8e-26 93.1 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 GAP86137.1 - 1.4e-40 139.1 9.5 5.5e-40 137.2 9.5 2.1 1 0 0 1 1 1 1 Up-frameshift suppressor 2 Mo-co_dimer PF03404.16 GAP86138.1 - 2.6e-60 202.4 0.1 5.6e-60 201.3 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 GAP86138.1 - 1.4e-55 187.5 0.0 2.4e-55 186.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 GAP86138.1 - 4.9e-32 110.2 0.0 8.7e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAP86138.1 - 3e-24 85.8 0.0 5.7e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 GAP86138.1 - 1.1e-21 76.7 0.0 9.2e-21 73.8 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 GAP86138.1 - 0.0066 16.6 0.0 0.073 13.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 GAP86139.1 - 8.2e-41 140.1 0.0 1.2e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP86139.1 - 7.7e-13 48.8 0.0 1.8e-10 41.3 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 GAP86139.1 - 1.3e-06 27.5 0.4 3.7e-06 26.1 0.3 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 GAP86139.1 - 1.4e-05 24.7 0.5 4.5e-05 23.0 0.5 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 GAP86139.1 - 0.0001 21.6 0.9 0.00027 20.3 0.9 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 GAP86139.1 - 0.00035 21.0 0.0 0.00077 19.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.6 GAP86139.1 - 0.26 10.5 0.7 1.7 7.8 0.7 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Nop53 PF07767.11 GAP86140.1 - 3e-106 356.2 26.8 3.4e-106 356.0 26.8 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Ras PF00071.22 GAP86141.1 - 5.3e-59 198.4 0.4 6.8e-59 198.1 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP86141.1 - 1.6e-37 128.4 0.1 2.5e-37 127.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP86141.1 - 1.8e-17 63.3 0.4 2.3e-17 63.0 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAP86141.1 - 3.3e-06 26.8 0.1 3e-05 23.7 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 GAP86141.1 - 1.3e-05 24.7 0.1 1.7e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAP86141.1 - 1.6e-05 25.0 0.1 3.3e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAP86141.1 - 2e-05 24.1 0.4 2.5e-05 23.8 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAP86141.1 - 0.00063 19.7 0.2 0.37 10.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 GAP86141.1 - 0.014 15.2 0.1 0.044 13.6 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FlgH PF02107.16 GAP86141.1 - 0.041 13.5 0.5 0.058 13.0 0.5 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein AAA_28 PF13521.6 GAP86141.1 - 0.05 13.8 0.0 14 5.9 0.0 2.2 1 1 0 2 2 2 0 AAA domain TIR_2 PF13676.6 GAP86141.1 - 0.055 14.1 0.1 0.084 13.5 0.1 1.5 1 1 0 1 1 1 0 TIR domain TetR_C_16 PF17920.1 GAP86141.1 - 0.096 12.9 0.0 0.9 9.8 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Rib_5-P_isom_A PF06026.14 GAP86142.1 - 6.1e-42 143.1 0.0 1e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) NIR_SIR PF01077.22 GAP86143.1 - 1e-55 187.6 0.1 1.7e-50 170.6 0.1 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 GAP86143.1 - 3.8e-29 101.7 0.0 8.1e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 GAP86143.1 - 4.7e-29 100.0 0.0 5.7e-14 51.7 0.1 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 GAP86143.1 - 1.2e-05 25.2 0.3 2.8e-05 24.0 0.1 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 GAP86143.1 - 0.0004 20.6 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II AltA1 PF16541.5 GAP86144.1 - 3.7e-08 34.2 1.6 5.2e-08 33.7 1.6 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Lipase_3 PF01764.25 GAP86145.1 - 1.4e-31 109.2 0.0 2e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GAP86145.1 - 0.0012 19.5 0.3 0.0019 18.8 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 GAP86145.1 - 0.042 13.4 0.8 2 7.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 GAP86145.1 - 0.083 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAP86145.1 - 0.23 11.2 0.0 0.38 10.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein 14-3-3 PF00244.20 GAP86146.1 - 2.6e-107 357.4 0.9 3e-107 357.2 0.9 1.0 1 0 0 1 1 1 1 14-3-3 protein Syja_N PF02383.18 GAP86147.1 - 8e-75 252.1 0.0 1.5e-74 251.2 0.0 1.4 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 GAP86147.1 - 2.4e-09 37.0 0.0 4.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BDHCT_assoc PF16204.5 GAP86147.1 - 0.11 12.2 1.0 0.23 11.1 1.0 1.5 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein LAMTOR5 PF16672.5 GAP86148.1 - 0.02 14.8 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 TPR_14 PF13428.6 GAP86149.1 - 3.7e-05 24.2 7.0 0.03 15.1 0.0 6.5 5 2 2 7 7 7 1 Tetratricopeptide repeat Suf PF05843.14 GAP86149.1 - 0.0072 16.3 8.3 1.9 8.4 0.3 4.0 4 1 0 4 4 4 3 Suppressor of forked protein (Suf) peroxidase PF00141.23 GAP86150.1 - 8.5e-49 166.3 0.0 1.5e-48 165.5 0.0 1.4 1 0 0 1 1 1 1 Peroxidase PAN_4 PF14295.6 GAP86151.1 - 0.015 15.2 1.4 0.047 13.6 1.4 1.8 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.12 GAP86151.1 - 0.023 14.5 1.9 0.13 12.1 1.9 2.3 1 0 0 1 1 1 0 PAN-like domain PAN_1 PF00024.26 GAP86151.1 - 0.031 14.2 1.0 0.031 14.2 1.0 2.2 2 0 0 2 2 2 0 PAN domain ATP11 PF06644.11 GAP86152.1 - 4.7e-57 193.8 0.0 1.7e-38 133.0 0.0 2.1 2 0 0 2 2 2 2 ATP11 protein DUF3439 PF11921.8 GAP86152.1 - 0.07 13.1 9.4 0.12 12.4 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAP86152.1 - 0.15 12.1 14.6 0.26 11.3 14.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 GAP86152.1 - 1.9 6.6 17.7 0.28 9.3 13.5 1.6 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 GAP86152.1 - 3 5.7 5.5 3.9 5.3 5.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AMP-binding PF00501.28 GAP86153.1 - 5.7e-96 321.7 0.0 6.6e-96 321.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP86153.1 - 2.6e-14 53.9 0.2 5.2e-14 53.0 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SpecificRecomb PF10136.9 GAP86153.1 - 0.13 10.6 0.3 0.18 10.0 0.3 1.1 1 0 0 1 1 1 0 Site-specific recombinase Abhydro_lipase PF04083.16 GAP86154.1 - 7.4e-20 70.3 0.0 1.5e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 GAP86154.1 - 1e-06 28.6 0.1 3.3e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP86154.1 - 0.0052 16.1 0.0 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF676 PF05057.14 GAP86154.1 - 0.26 10.8 0.0 0.43 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA PF00004.29 GAP86155.1 - 2.2e-48 164.0 0.0 7e-43 146.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP86155.1 - 0.00012 22.5 0.2 0.021 15.2 0.0 3.0 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAP86155.1 - 0.00019 21.2 0.0 0.00057 19.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 GAP86155.1 - 0.00078 18.6 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 GAP86155.1 - 0.0035 17.5 0.0 0.009 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 GAP86155.1 - 0.0057 16.3 0.0 0.028 14.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 GAP86155.1 - 0.0068 15.6 0.0 0.02 14.1 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 GAP86155.1 - 0.0071 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 GAP86155.1 - 0.01 16.1 0.0 0.037 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAP86155.1 - 0.011 16.1 0.0 0.04 14.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 GAP86155.1 - 0.021 14.2 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAP86155.1 - 0.035 14.1 0.0 0.14 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 GAP86155.1 - 0.037 13.4 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 GAP86155.1 - 0.046 13.2 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 GAP86155.1 - 0.071 12.6 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 GAP86155.1 - 0.078 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 GAP86155.1 - 0.089 11.9 0.3 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 GAP86155.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 GAP86155.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAP86155.1 - 0.12 12.5 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_lid_3 PF17862.1 GAP86155.1 - 0.49 10.3 2.3 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 AAA+ lid domain SH3BGR PF04908.15 GAP86156.1 - 0.00016 21.7 0.0 0.00052 20.1 0.0 2.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein TFIIA PF03153.13 GAP86156.1 - 0.023 14.7 23.9 0.042 13.9 23.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 GAP86156.1 - 0.077 11.2 29.4 0.1 10.8 29.4 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 GAP86156.1 - 0.32 10.3 34.0 0.49 9.7 34.0 1.3 1 0 0 1 1 1 0 BUD22 LAT PF15234.6 GAP86157.1 - 1.9 8.1 5.7 2.2 7.9 5.7 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells GCIP PF13324.6 GAP86157.1 - 2.2 7.8 5.6 2.4 7.7 5.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.9 GAP86157.1 - 3.9 6.5 12.1 4.2 6.4 12.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 GAP86157.1 - 7.1 7.1 14.8 8.7 6.8 14.8 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MAD PF05557.13 GAP86158.1 - 0.00069 18.1 4.9 0.0013 17.2 4.9 1.5 1 1 0 1 1 1 1 Mitotic checkpoint protein DUF5082 PF16888.5 GAP86158.1 - 0.0039 17.5 2.6 0.0048 17.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) DUF1664 PF07889.12 GAP86158.1 - 0.055 13.5 0.7 0.11 12.6 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Phe_tRNA-synt_N PF02912.18 GAP86158.1 - 0.055 13.4 1.4 0.055 13.4 1.4 2.5 2 1 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain AIP3 PF03915.13 GAP86158.1 - 0.066 12.3 1.9 0.11 11.6 1.9 1.4 1 0 0 1 1 1 0 Actin interacting protein 3 T3SSipB PF16535.5 GAP86158.1 - 0.32 11.5 6.6 0.49 10.9 6.6 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB MRPL52 PF18699.1 GAP86158.1 - 0.79 10.0 5.7 14 5.9 1.4 2.7 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Halo_GVPC PF05465.13 GAP86158.1 - 1.9 8.8 4.7 7.1 7.0 0.0 3.1 3 1 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF2390 PF09523.10 GAP86158.1 - 2.1 8.7 10.6 0.29 11.5 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) DUF4407 PF14362.6 GAP86158.1 - 8.6 5.6 12.5 13 5.0 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_16 PF00722.21 GAP86159.1 - 1.9e-07 30.7 0.0 4.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_transf_34 PF05637.12 GAP86160.1 - 2.2e-64 217.4 1.1 3.3e-64 216.9 1.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 GAP86160.1 - 0.056 13.4 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF724 PF05266.14 GAP86161.1 - 0.0013 18.6 5.4 0.0081 16.0 5.4 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) PKcGMP_CC PF16808.5 GAP86161.1 - 0.028 14.2 3.8 0.38 10.6 0.5 3.0 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 GAP86161.1 - 0.11 12.9 8.9 0.36 11.2 2.8 3.5 2 1 0 2 2 2 0 Csm1 N-terminal domain DUF4200 PF13863.6 GAP86161.1 - 0.17 12.3 12.0 4.8 7.6 3.0 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.8 GAP86161.1 - 0.67 10.2 11.4 3.9 7.7 11.4 2.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.6 GAP86161.1 - 1.1 9.4 11.6 3.4 7.8 3.7 3.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Fungal_trans PF04082.18 GAP86162.1 - 3.7e-08 32.7 0.0 7.8e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP86162.1 - 1.3e-07 31.6 9.8 2.5e-07 30.7 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 GAP86162.1 - 1.8 8.5 7.2 3 7.7 7.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 GAP86162.1 - 1.9 6.7 7.1 2.7 6.2 7.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 URO-D PF01208.17 GAP86164.1 - 1e-95 320.8 0.0 1.3e-95 320.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) FR47 PF08445.10 GAP86165.1 - 0.00031 20.7 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 GAP86165.1 - 0.0028 17.9 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DUF3602 PF12223.8 GAP86166.1 - 2.2e-16 60.2 15.9 7.9e-13 48.8 2.9 2.7 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Velvet PF11754.8 GAP86167.1 - 1.5e-89 300.3 0.0 1.9e-89 299.9 0.0 1.2 1 0 0 1 1 1 1 Velvet factor RhoGEF PF00621.20 GAP86168.1 - 1.1e-32 113.8 0.4 1.1e-32 113.8 0.4 2.3 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.18 GAP86168.1 - 1.2e-08 35.0 0.5 1.2e-08 35.0 0.5 2.4 3 0 0 3 3 3 1 BAR domain HlyE PF06109.13 GAP86168.1 - 0.15 11.3 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 Haemolysin E (HlyE) ATP-synt_E PF05680.12 GAP86168.1 - 3.2 8.2 10.5 4.2 7.8 0.4 3.3 2 0 0 2 2 2 0 ATP synthase E chain Telomerase_RBD PF12009.8 GAP86169.1 - 6.1e-48 162.3 4.2 1.8e-47 160.8 4.2 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 GAP86169.1 - 2.1e-14 53.6 0.0 6.7e-11 42.1 0.1 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MarR PF01047.22 GAP86169.1 - 0.11 12.4 0.0 0.4 10.7 0.0 2.0 1 0 0 1 1 1 0 MarR family Peptidase_C48 PF02902.19 GAP86171.1 - 1.1e-17 64.6 0.7 5.3e-17 62.4 0.7 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1640 PF07798.11 GAP86172.1 - 1e-55 188.5 9.9 1.4e-55 188.1 9.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 GAP86172.1 - 0.038 13.4 0.7 0.1 12.0 0.1 1.8 1 1 1 2 2 2 0 GNAT acetyltransferase 2 CPSase_L_D2 PF02786.17 GAP86173.1 - 2.1e-110 367.2 0.0 2.8e-84 281.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 GAP86173.1 - 3.4e-40 137.2 0.0 1e-39 135.7 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 GAP86173.1 - 3e-19 69.2 0.1 5e-09 36.0 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAP86173.1 - 3.1e-19 69.3 0.3 1.5e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 GAP86173.1 - 2.1e-11 43.7 0.0 0.00018 21.3 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 GAP86173.1 - 0.00013 21.8 0.2 0.27 11.0 0.1 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 GAP86173.1 - 0.00045 19.7 0.1 1.2 8.5 0.0 3.0 2 1 1 3 3 3 2 ATP-grasp domain NPL4 PF05021.15 GAP86174.1 - 3.8e-137 456.7 0.0 5.2e-137 456.3 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 GAP86174.1 - 2.9e-66 222.1 0.0 4.3e-66 221.5 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 GAP86174.1 - 0.00089 19.7 0.0 0.0023 18.4 0.0 1.7 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF2417 PF10329.9 GAP86175.1 - 1.7e-82 276.4 0.8 2.2e-82 276.0 0.8 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DHHC PF01529.20 GAP86175.1 - 0.86 9.7 6.8 9.6 6.3 1.7 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase SLX9 PF15341.6 GAP86176.1 - 5.1e-37 127.2 5.9 7.1e-37 126.7 5.9 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 MBOAT_2 PF13813.6 GAP86177.1 - 3.7e-15 56.0 1.6 3.7e-15 56.0 1.6 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family HisG PF01634.18 GAP86178.1 - 9.7e-57 191.4 0.0 1.5e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 GAP86178.1 - 8.5e-28 96.3 0.1 1.5e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 GAP86178.1 - 0.0051 16.8 0.0 0.56 10.1 0.0 2.3 2 0 0 2 2 2 2 NMT1/THI5 like MFS_2 PF13347.6 GAP86179.1 - 8.3e-12 44.4 8.2 8.3e-12 44.4 8.2 2.8 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 GAP86179.1 - 1.6e-05 23.9 1.1 5.9e-05 22.1 1.1 2.0 2 1 0 2 2 2 1 MFS_1 like family PUCC PF03209.15 GAP86179.1 - 0.0047 16.0 2.9 0.0091 15.0 2.9 1.4 1 0 0 1 1 1 1 PUCC protein DDDD PF10161.9 GAP86179.1 - 0.14 11.9 0.0 0.49 10.2 0.0 1.9 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Glycos_transf_4 PF00953.21 GAP86179.1 - 2 8.4 8.5 0.49 10.3 0.7 3.2 3 0 0 3 3 3 0 Glycosyl transferase family 4 Rep_fac_C PF08542.11 GAP86180.1 - 7.3e-18 64.8 0.0 1.5e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 GAP86180.1 - 9.9e-16 58.4 0.0 2.3e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GAP86180.1 - 1.1e-12 48.0 0.0 7.5e-08 32.3 0.0 2.5 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 GAP86180.1 - 1.8e-09 37.8 0.0 5.2e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 GAP86180.1 - 2.9e-06 27.1 0.1 1.8e-05 24.5 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 GAP86180.1 - 1.6e-05 25.1 0.2 4.9e-05 23.6 0.2 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 GAP86180.1 - 1.9e-05 25.0 0.1 0.0025 18.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAP86180.1 - 2e-05 25.0 0.0 0.00081 19.8 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_11 PF13086.6 GAP86180.1 - 3.4e-05 23.7 0.1 0.00012 22.0 0.0 1.6 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 GAP86180.1 - 0.00019 20.9 0.0 0.0079 15.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 GAP86180.1 - 0.00023 21.0 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 GAP86180.1 - 0.0013 18.8 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAP86180.1 - 0.0016 18.8 0.0 0.009 16.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAP86180.1 - 0.0032 17.2 0.0 0.029 14.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 GAP86180.1 - 0.0032 16.7 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAP86180.1 - 0.0047 16.5 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 GAP86180.1 - 0.01 15.8 0.1 0.095 12.7 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 GAP86180.1 - 0.014 15.1 0.0 0.058 13.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 GAP86180.1 - 0.017 15.3 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAP86180.1 - 0.047 14.2 0.0 0.12 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 GAP86180.1 - 0.052 13.5 0.0 0.21 11.6 0.0 1.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 GAP86180.1 - 0.061 12.5 0.0 0.22 10.7 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 GAP86180.1 - 0.065 13.1 0.0 0.4 10.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 GAP86180.1 - 0.12 11.8 0.0 2.6 7.4 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein RNA_helicase PF00910.22 GAP86180.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF664 PF04978.12 GAP86181.1 - 1 9.8 7.1 0.38 11.1 0.3 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF664) V_ATPase_I PF01496.19 GAP86181.1 - 9.1 4.1 9.0 0.21 9.5 1.9 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Sec63 PF02889.16 GAP86182.1 - 5.7e-166 550.0 0.1 4.4e-92 307.9 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GAP86182.1 - 1.3e-47 161.8 0.0 2.2e-27 95.9 0.1 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 GAP86182.1 - 1.7e-33 115.1 1.9 2e-33 114.9 0.3 2.1 2 0 0 2 2 1 1 N-terminal helicase PWI domain ResIII PF04851.15 GAP86182.1 - 1.9e-25 89.8 0.0 1.3e-13 51.3 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAP86182.1 - 2e-12 47.5 0.0 3.8e-07 30.4 0.0 3.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAP86182.1 - 2.2e-08 34.4 0.1 0.00096 19.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 GAP86182.1 - 0.0012 18.4 0.0 0.18 11.3 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 GAP86182.1 - 0.0017 17.5 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein TFIIE_alpha PF02002.17 GAP86182.1 - 0.049 13.5 1.4 12 5.8 0.1 3.4 3 0 0 3 3 3 0 TFIIE alpha subunit DUF2075 PF09848.9 GAP86182.1 - 0.099 11.9 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 GAP86182.1 - 0.13 12.0 0.1 12 5.6 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.6 GAP86182.1 - 0.17 12.3 0.6 45 4.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain PWWP PF00855.17 GAP86183.1 - 2.5e-15 56.6 2.7 4.1e-15 55.9 0.0 2.7 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.11 GAP86183.1 - 0.0034 17.4 0.1 0.0073 16.3 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF1299 PF06975.11 GAP86183.1 - 0.0045 17.0 1.5 0.0045 17.0 1.5 5.0 6 0 0 6 6 6 2 Protein of unknown function (DUF1299) AF-4 PF05110.13 GAP86184.1 - 0.00045 18.5 1.3 0.00067 17.9 1.3 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Co_AT_N PF12557.8 GAP86184.1 - 6 6.9 7.2 0.67 9.9 2.7 1.8 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal UQ_con PF00179.26 GAP86185.1 - 4.6e-44 149.5 0.0 1e-30 106.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAP86185.1 - 0.0017 18.0 0.0 0.075 12.7 0.0 2.8 3 0 0 3 3 3 1 Prokaryotic E2 family B UEV PF05743.13 GAP86185.1 - 0.028 14.3 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 UEV domain 3Beta_HSD PF01073.19 GAP86186.1 - 1.1e-66 224.7 0.0 1.5e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAP86186.1 - 5.8e-33 114.3 0.2 8e-33 113.9 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP86186.1 - 2.3e-18 66.7 0.0 5.9e-15 55.5 0.1 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 GAP86186.1 - 2.9e-13 49.6 1.3 5.2e-11 42.2 0.2 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 GAP86186.1 - 1e-12 47.7 0.1 1.4e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAP86186.1 - 1.5e-11 44.5 0.0 3.9e-11 43.2 0.0 1.6 1 1 1 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAP86186.1 - 1.6e-07 30.8 0.0 8.3e-07 28.4 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 GAP86186.1 - 2.3e-06 27.8 0.4 5.8e-05 23.3 0.1 2.6 2 1 1 3 3 3 1 TrkA-N domain NmrA PF05368.13 GAP86186.1 - 0.00026 20.6 0.0 0.00064 19.3 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 GAP86186.1 - 0.00037 20.4 0.5 0.0025 17.8 0.5 2.2 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 GAP86186.1 - 0.095 13.0 0.1 0.82 9.9 0.1 2.6 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain RhoGAP PF00620.27 GAP86187.1 - 1.7e-38 131.8 0.0 4.6e-38 130.4 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 GAP86187.1 - 5.2e-32 109.9 40.3 1.3e-11 44.5 6.9 5.1 5 0 0 5 5 5 4 LIM domain Desulfoferrod_N PF06397.12 GAP86187.1 - 0.087 12.5 0.3 0.44 10.2 0.3 2.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain DZR PF12773.7 GAP86187.1 - 6.3 6.9 30.4 0.45 10.6 2.2 5.1 3 2 1 4 4 4 0 Double zinc ribbon HMG_box PF00505.19 GAP86188.1 - 6.3e-05 23.3 0.2 6.3e-05 23.3 0.2 2.6 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAP86188.1 - 0.00014 22.4 0.4 0.0007 20.1 0.0 2.3 2 0 0 2 2 2 1 HMG-box domain Transposase_24 PF03004.14 GAP86188.1 - 0.094 12.8 7.0 0.064 13.4 1.4 2.7 1 1 2 3 3 3 0 Plant transposase (Ptta/En/Spm family) 4HBT_3 PF13622.6 GAP86188.1 - 1.1 9.5 5.9 0.53 10.5 1.4 2.0 2 0 0 2 2 2 0 Thioesterase-like superfamily AIF_C PF14721.6 GAP86188.1 - 5.9 7.3 5.6 32 4.9 0.9 2.6 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DEAD PF00270.29 GAP86189.1 - 1.8e-50 171.1 0.0 1.5e-49 168.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP86189.1 - 7.9e-28 97.0 0.0 2.6e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP86189.1 - 0.0082 16.2 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-H2C2_2 PF13465.6 GAP86190.1 - 2.7e-23 81.3 21.7 3.4e-08 33.6 0.2 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 GAP86190.1 - 4.9e-21 73.9 29.4 3.3e-05 24.1 0.3 6.9 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP86190.1 - 1.7e-16 59.4 21.1 0.0022 18.6 0.4 7.0 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP86190.1 - 7.9e-05 22.8 3.7 0.14 12.4 0.0 4.5 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAP86190.1 - 0.00041 20.3 17.5 0.27 11.3 0.8 4.9 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GAP86190.1 - 0.00071 19.4 6.1 0.65 10.0 0.2 3.7 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-met PF12874.7 GAP86190.1 - 0.0064 16.8 0.5 0.0064 16.8 0.5 4.2 6 0 0 6 6 5 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 GAP86190.1 - 0.011 16.0 9.8 0.3 11.4 3.4 3.3 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf_UBZ PF18439.1 GAP86190.1 - 0.032 13.8 1.7 4.6 6.9 0.2 3.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 GAP86190.1 - 0.42 10.4 11.2 0.9 9.4 0.0 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type BolA PF01722.18 GAP86190.1 - 0.51 10.6 3.5 47 4.3 0.0 3.3 3 0 0 3 3 3 0 BolA-like protein Ribosomal_L29 PF00831.23 GAP86191.1 - 8.1e-17 60.9 0.6 8.1e-17 60.9 0.6 2.4 1 1 2 3 3 3 1 Ribosomal L29 protein Taeniidae_ag PF05596.11 GAP86191.1 - 0.11 12.5 2.3 6.3 6.9 0.6 2.4 2 0 0 2 2 2 0 Taeniidae antigen V-SNARE_C PF12352.8 GAP86192.1 - 2.8e-13 49.9 0.5 2.8e-13 49.9 0.5 2.9 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus LptF_LptG PF03739.14 GAP86192.1 - 0.0077 15.1 0.0 0.013 14.4 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG STAT_alpha PF01017.20 GAP86192.1 - 0.0087 16.0 1.0 0.0087 16.0 1.0 2.4 1 1 1 2 2 2 1 STAT protein, all-alpha domain Spc7 PF08317.11 GAP86192.1 - 0.039 12.8 12.3 0.014 14.3 10.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2730 PF10805.8 GAP86192.1 - 0.094 12.8 1.4 4.6 7.4 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) AIM5 PF17050.5 GAP86192.1 - 0.44 11.4 6.6 0.11 13.4 2.0 2.2 2 1 0 2 2 2 0 Altered inheritance of mitochondria 5 FTA4 PF13093.6 GAP86192.1 - 1.3 8.9 13.7 12 5.7 12.4 2.6 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Atg14 PF10186.9 GAP86192.1 - 1.6 7.7 14.4 1.9 7.5 12.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CorA PF01544.18 GAP86192.1 - 2.2 7.5 12.1 6.4 6.0 6.6 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF1451 PF07295.11 GAP86192.1 - 3.7 7.6 5.5 5.6 7.0 4.0 1.9 1 1 1 2 2 2 0 Zinc-ribbon containing domain FUSC PF04632.12 GAP86192.1 - 7.7 4.9 9.2 5.7 5.4 7.8 1.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family ATP-synt_10 PF05176.14 GAP86193.1 - 7e-53 179.5 0.0 7.9e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein 2-oxoacid_dh PF00198.23 GAP86194.1 - 8.5e-76 254.5 0.3 1.2e-75 254.0 0.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAP86194.1 - 1.7e-16 59.8 0.1 3.7e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAP86194.1 - 7.3e-13 48.6 0.0 1.5e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain SKI PF01202.22 GAP86195.1 - 1.5e-11 44.6 0.0 1.9e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 GAP86195.1 - 1.1e-09 38.5 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAP86195.1 - 6e-09 36.5 0.0 1.7e-08 35.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 GAP86195.1 - 1.6e-05 25.0 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 GAP86195.1 - 3.6e-05 23.6 0.0 5.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA_17 PF13207.6 GAP86195.1 - 0.00042 20.8 0.0 0.0034 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP86195.1 - 0.00063 20.2 0.0 0.0012 19.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 GAP86195.1 - 0.00078 19.7 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAP86195.1 - 0.0015 18.8 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAP86195.1 - 0.0016 18.8 0.0 0.0031 18.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 GAP86195.1 - 0.0023 17.3 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI dNK PF01712.19 GAP86195.1 - 0.0032 17.3 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_5 PF07728.14 GAP86195.1 - 0.0036 17.3 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PRK PF00485.18 GAP86195.1 - 0.0043 16.8 0.0 0.0064 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 GAP86195.1 - 0.0047 16.9 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 GAP86195.1 - 0.01 15.8 0.0 0.036 14.0 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 GAP86195.1 - 0.014 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAP86195.1 - 0.015 15.6 0.1 0.029 14.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 GAP86195.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 GAP86195.1 - 0.018 15.5 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 GAP86195.1 - 0.021 14.7 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 GAP86195.1 - 0.029 14.1 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 GAP86195.1 - 0.029 14.5 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase-like family CoaE PF01121.20 GAP86195.1 - 0.035 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase ATP_bind_1 PF03029.17 GAP86195.1 - 0.04 13.7 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 GAP86195.1 - 0.048 14.2 0.0 0.072 13.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 GAP86195.1 - 0.053 13.6 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 GAP86195.1 - 0.057 12.5 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Thermopsin PF05317.11 GAP86195.1 - 0.076 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Thermopsin TsaE PF02367.17 GAP86195.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE tRNA_lig_kinase PF08303.11 GAP86195.1 - 0.14 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain SRP54 PF00448.22 GAP86195.1 - 0.16 11.6 0.0 0.92 9.1 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 GAP86195.1 - 0.19 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 GAP86195.1 - 0.21 11.1 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_M49 PF03571.15 GAP86196.1 - 5e-240 797.6 0.0 5.9e-240 797.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.10 GAP86196.1 - 0.28 11.4 1.2 0.57 10.4 1.2 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain Ribosomal_L6e PF01159.19 GAP86197.1 - 6.7e-41 139.3 0.4 6.7e-41 139.3 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.13 GAP86198.1 - 2.9e-25 88.6 0.0 4.6e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 GAP86198.1 - 9.6e-10 38.6 0.4 1e-08 35.3 0.4 2.2 1 1 0 1 1 1 1 UCH-binding domain DMP1 PF07263.11 GAP86198.1 - 0.24 10.2 4.8 0.32 9.8 4.8 1.1 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) DUF3294 PF07957.11 GAP86199.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3294) ORC3_N PF07034.11 GAP86200.1 - 2.7e-43 148.4 1.4 2.2e-41 142.1 1.4 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 GAP86200.1 - 3.6e-27 95.1 0.3 7e-16 58.6 0.0 2.5 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal UPF0014 PF03649.13 GAP86200.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) RL10P_insert PF17777.1 GAP86201.1 - 6.5e-22 77.3 0.0 1.3e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 GAP86201.1 - 2.1e-20 72.7 0.1 5.3e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 GAP86201.1 - 2.3e-14 53.7 2.0 2.3e-14 53.7 2.0 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein PPR_2 PF13041.6 GAP86201.1 - 5.9e-10 39.2 0.0 0.01 16.0 0.0 5.1 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.20 GAP86201.1 - 0.00063 19.8 0.1 1.8 9.0 0.0 4.5 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 GAP86201.1 - 0.016 15.3 0.0 39 4.4 0.0 3.9 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAP86201.1 - 0.14 11.9 1.0 17 5.2 0.0 3.6 4 0 0 4 4 4 0 PPR repeat MutS_V PF00488.21 GAP86202.1 - 1.4e-67 227.4 0.0 3.1e-67 226.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAP86202.1 - 1.5e-45 155.8 1.2 2.3e-45 155.2 1.2 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 GAP86202.1 - 1.3e-20 73.7 0.0 3.3e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 GAP86202.1 - 2e-08 34.6 0.0 5.3e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 MutS domain II Glyco_hydro_38N PF01074.22 GAP86204.1 - 1.3e-88 297.1 1.0 2.4e-88 296.2 1.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 GAP86204.1 - 1.4e-56 192.0 0.0 1.6e-55 188.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 GAP86204.1 - 1.1e-24 86.4 0.0 2.3e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 GAP86204.1 - 1.4e-08 34.7 0.0 3.7e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 GAP86204.1 - 0.0057 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 CAP_GLY PF01302.25 GAP86205.1 - 3.8e-16 58.8 0.7 7.3e-16 57.9 0.7 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 GAP86205.1 - 5.4e-07 29.3 9.8 0.00015 21.6 1.1 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle NPV_P10 PF05531.12 GAP86205.1 - 0.037 14.5 0.8 0.037 14.5 0.8 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 GAP86205.1 - 0.039 14.3 11.8 0.081 13.2 2.7 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med4 PF10018.9 GAP86205.1 - 0.04 13.6 16.9 0.03 14.0 4.3 2.8 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 HemX PF04375.14 GAP86205.1 - 0.31 10.3 19.6 0.014 14.7 5.3 3.0 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Glutaredoxin2_C PF04399.13 GAP86205.1 - 0.51 10.2 4.7 3.2 7.6 0.4 2.5 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Spc29 PF17082.5 GAP86205.1 - 0.65 9.8 24.9 0.7 9.7 2.4 3.7 1 1 2 3 3 3 0 Spindle Pole Component 29 DUF3584 PF12128.8 GAP86205.1 - 0.72 7.3 29.2 1.2 6.6 29.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FliD_N PF02465.18 GAP86205.1 - 0.77 10.5 7.9 10 6.9 0.5 2.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Spc7 PF08317.11 GAP86205.1 - 0.89 8.4 35.7 0.47 9.3 13.1 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein EzrA PF06160.12 GAP86205.1 - 0.9 7.6 15.8 6.6 4.8 15.8 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 GAP86205.1 - 1.4 9.1 21.2 1.1 9.4 0.7 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family DUF812 PF05667.11 GAP86205.1 - 3.3 6.5 32.0 0.52 9.1 20.6 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 GAP86205.1 - 3.3 7.7 5.2 3 7.9 1.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 GAP86205.1 - 3.6 6.1 20.1 0.023 13.3 7.8 1.8 2 1 1 3 3 3 0 AAA domain DUF948 PF06103.11 GAP86205.1 - 4.1 7.7 4.0 2.7 8.3 1.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 GAP86205.1 - 4.6 7.6 13.8 20 5.6 1.5 3.8 2 1 1 3 3 3 0 Uncharacterized conserved protein Flagellin_N PF00669.20 GAP86205.1 - 5.2 7.2 10.5 0.44 10.6 0.1 3.4 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region Fez1 PF06818.15 GAP86205.1 - 8.9 6.7 38.4 46 4.4 25.0 3.3 1 1 1 2 2 2 0 Fez1 Nop14 PF04147.12 GAP86207.1 - 9.2e-262 871.2 19.0 1.3e-261 870.7 19.0 1.2 1 0 0 1 1 1 1 Nop14-like family bZIP_2 PF07716.15 GAP86208.1 - 0.25 11.5 14.8 0.1 12.7 10.7 2.3 2 1 0 2 2 2 0 Basic region leucine zipper DnaJ_C PF01556.18 GAP86209.1 - 1.2e-37 129.3 0.2 1.5e-37 128.9 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAP86209.1 - 1.1e-25 89.5 1.3 1.9e-25 88.7 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAP86209.1 - 9.1e-16 58.0 18.5 1.8e-15 57.0 18.5 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAP86209.1 - 0.058 13.4 19.0 0.45 10.5 6.7 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 GAP86209.1 - 0.077 13.0 9.3 1.9 8.5 0.8 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 GAP86209.1 - 0.66 10.0 6.2 4.8 7.3 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 GAP86209.1 - 1.2 9.1 7.2 28 4.8 7.2 2.3 1 1 0 1 1 1 0 zinc-ribbons DUF2614 PF11023.8 GAP86209.1 - 1.6 8.8 6.3 6.2 7.0 1.1 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain zinc_ribbon_9 PF14369.6 GAP86209.1 - 1.7 9.0 4.0 46 4.4 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon WD40 PF00400.32 GAP86210.1 - 0.0044 17.8 1.8 0.35 11.8 0.2 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat VCBS PF13517.6 GAP86210.1 - 0.02 15.5 0.2 0.79 10.4 0.0 2.8 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CPSF_A PF03178.15 GAP86210.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 2 0 0 2 2 2 0 CPSF A subunit region RecA_dep_nuc PF16786.5 GAP86210.1 - 0.03 14.4 0.2 0.22 11.7 0.0 2.4 3 0 0 3 3 3 0 Recombination enhancement, RecA-dependent nuclease DUF2880 PF11082.8 GAP86210.1 - 0.52 10.7 3.4 14 6.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2880) Pkinase PF00069.25 GAP86211.1 - 8.4e-37 127.0 0.0 2.2e-20 73.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86211.1 - 1.4e-16 60.6 0.0 3.6e-07 29.7 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 GAP86211.1 - 1.7e-05 24.9 0.0 2.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAP86211.1 - 0.0068 15.8 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like DUF4187 PF13821.6 GAP86212.1 - 3.2e-20 71.7 2.5 3.2e-20 71.7 2.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 GAP86212.1 - 8.8e-09 35.1 0.7 1.5e-08 34.4 0.7 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAP86212.1 - 0.0004 20.4 0.9 0.0012 18.8 0.9 1.9 1 0 0 1 1 1 1 G-patch domain dCMP_cyt_deam_1 PF00383.23 GAP86213.1 - 4.2e-06 26.6 0.0 4.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region UPF0515 PF15135.6 GAP86213.1 - 0.00094 18.6 0.1 0.0012 18.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 MafB19-deam PF14437.6 GAP86213.1 - 0.0029 17.4 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase DUF1556 PF07590.11 GAP86213.1 - 0.1 12.9 1.5 0.17 12.2 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) Abhydrolase_1 PF00561.20 GAP86214.1 - 5.1e-14 52.5 1.1 3.1e-11 43.4 0.5 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP86214.1 - 0.00028 21.5 9.7 0.00042 21.0 9.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAH PF01426.18 GAP86215.1 - 5.5e-18 65.0 0.1 1.3e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.6 GAP86215.1 - 1.4e-17 63.9 2.1 1.4e-17 63.9 2.1 4.3 4 1 0 4 4 4 2 PHD-zinc-finger like domain PHD PF00628.29 GAP86215.1 - 7.6e-15 54.5 57.2 3.1e-08 33.4 12.1 6.0 6 0 0 6 6 6 3 PHD-finger zf-HC5HC2H PF13771.6 GAP86215.1 - 1.2e-13 51.1 3.9 1.2e-13 51.1 3.9 5.2 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 GAP86215.1 - 7.1e-09 35.1 7.2 7.1e-09 35.1 7.2 5.0 6 0 0 6 6 6 2 PHD-finger ELM2 PF01448.24 GAP86215.1 - 0.2 12.4 2.6 2.7 8.8 0.1 3.1 2 0 0 2 2 2 0 ELM2 domain Prok-RING_1 PF14446.6 GAP86215.1 - 0.21 11.5 39.3 0.12 12.3 7.6 4.2 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 DEAD PF00270.29 GAP86216.1 - 2e-16 60.3 0.0 6.6e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP86216.1 - 2.1e-08 34.5 0.0 1.2e-06 28.8 0.0 3.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP86216.1 - 0.00058 19.9 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 GAP86216.1 - 0.0026 18.3 0.0 0.0083 16.7 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain COesterase PF00135.28 GAP86217.1 - 6.6e-59 200.1 0.0 9e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP86217.1 - 7.5e-06 25.9 3.6 5.9e-05 23.0 3.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP86217.1 - 0.073 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAP86218.1 - 4.7e-09 36.3 0.0 7.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP86218.1 - 3.7e-05 23.1 0.0 6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SNARE_assoc PF09335.11 GAP86220.1 - 5.8e-16 59.1 6.2 5.8e-16 59.1 6.2 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein Beta-lactamase PF00144.24 GAP86221.1 - 5.9e-61 206.5 0.0 7.2e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase G-patch PF01585.23 GAP86222.1 - 0.0015 18.4 0.1 0.003 17.4 0.1 1.5 1 0 0 1 1 1 1 G-patch domain MFS_1 PF07690.16 GAP86223.1 - 8.2e-44 150.0 33.9 6.6e-43 147.0 17.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 GAP86224.1 - 3e-05 24.1 10.1 6.1e-05 23.1 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAP30_Sin3_bdg PF13867.6 GAP86225.1 - 1.1e-09 38.5 1.4 6.9e-09 35.9 0.4 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DnaJ PF00226.31 GAP86226.1 - 1.5e-23 82.7 1.4 2.6e-23 81.9 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 GAP86226.1 - 4.5e-16 59.3 0.0 1.7e-15 57.4 0.0 1.7 1 1 1 2 2 2 1 DnaJ C terminal domain BRO1 PF03097.18 GAP86227.1 - 3e-130 434.5 0.4 3e-130 434.5 0.4 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 GAP86227.1 - 2.6e-80 269.9 20.9 4.7e-80 269.0 20.9 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV FlaC_arch PF05377.11 GAP86227.1 - 0.044 14.2 1.3 0.15 12.5 0.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1810 PF08837.11 GAP86227.1 - 0.052 13.4 0.2 0.17 11.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) UBA_2 PF08587.11 GAP86227.1 - 0.062 13.4 0.0 0.25 11.5 0.0 2.0 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Gp58 PF07902.11 GAP86227.1 - 0.13 10.5 14.5 0.0057 15.0 6.3 2.2 1 1 1 2 2 2 0 gp58-like protein COG2 PF06148.11 GAP86227.1 - 0.61 10.2 9.3 0.22 11.6 3.0 3.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Avl9 PF09794.9 GAP86228.1 - 9.4e-143 475.5 0.0 1.2e-142 475.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 GAP86228.1 - 5.5e-06 26.3 0.0 0.00039 20.3 0.0 2.3 2 0 0 2 2 2 1 Stabilization of polarity axis DUF2347 PF09804.9 GAP86228.1 - 3e-05 23.8 1.8 0.0018 17.9 0.1 3.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Cullin PF00888.22 GAP86229.1 - 3e-192 640.5 12.4 3.7e-192 640.2 12.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAP86229.1 - 3.2e-24 84.7 2.8 3.2e-24 84.7 2.8 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 GAP86229.1 - 0.049 14.2 1.3 0.21 12.1 0.3 2.6 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal FAM194 PF14977.6 GAP86229.1 - 0.22 10.8 6.0 0.63 9.3 1.2 3.2 3 0 0 3 3 3 0 FAM194 protein DUF588 PF04535.12 GAP86230.1 - 0.0017 18.2 0.1 0.0029 17.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF588) Mit_KHE1 PF10173.9 GAP86231.1 - 6.9e-63 212.2 0.4 1e-62 211.6 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related NOA36 PF06524.12 GAP86232.1 - 6 6.1 18.4 3.7 6.8 2.3 2.1 2 0 0 2 2 2 0 NOA36 protein AvrPto PF11592.8 GAP86234.1 - 0.095 12.7 0.2 0.2 11.7 0.1 1.7 2 0 0 2 2 2 0 Central core of the bacterial effector protein AvrPto Ig_mannosidase PF17753.1 GAP86235.1 - 0.0056 16.4 1.8 0.011 15.5 1.8 1.5 1 1 0 1 1 1 1 Ig-fold domain Methyltransf_25 PF13649.6 GAP86238.1 - 2.5e-10 40.9 0.0 3.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP86238.1 - 1.3e-07 32.2 0.0 2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP86238.1 - 1.3e-06 28.1 0.0 1.8e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 GAP86238.1 - 1.5e-06 28.9 0.0 2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP86238.1 - 1.9e-06 27.7 0.0 2.5e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP86238.1 - 2e-06 27.3 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAP86238.1 - 0.00016 21.6 0.0 0.00022 21.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 GAP86238.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PrmA PF06325.13 GAP86238.1 - 0.049 13.0 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 GAP86238.1 - 0.077 12.6 0.0 0.085 12.5 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) 2_5_RNA_ligase2 PF13563.6 GAP86240.1 - 2.7e-29 102.1 0.0 1.2e-28 99.9 0.1 2.1 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 GAP86240.1 - 1.3e-20 73.5 0.0 2.4e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain MJ1316 PF04457.12 GAP86240.1 - 9.8e-20 71.1 0.3 2.3e-19 69.9 0.3 1.7 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Exo_endo_phos PF03372.23 GAP86240.1 - 1.8e-08 34.2 0.0 4.1e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 GAP86240.1 - 0.0017 18.6 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 GAP86240.1 - 0.017 14.9 0.2 0.07 12.9 0.0 2.1 3 0 0 3 3 3 0 Nrap protein PAP/OAS-like domain MCM PF00493.23 GAP86241.1 - 2.8e-97 324.2 0.3 4.7e-97 323.5 0.3 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAP86241.1 - 1.5e-30 105.6 0.0 2.9e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAP86241.1 - 4.9e-23 81.3 0.3 1e-22 80.3 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 GAP86241.1 - 4.3e-07 29.5 0.0 4.8e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 GAP86241.1 - 8.4e-05 23.1 0.1 0.00032 21.2 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_3 PF07726.11 GAP86241.1 - 0.0012 18.7 0.0 0.0056 16.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAP86241.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4804 PF16062.5 GAP86242.1 - 7.3e-91 305.2 0.0 1.1e-55 189.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4804) adh_short PF00106.25 GAP86243.1 - 1e-32 113.2 0.1 1.3e-32 112.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP86243.1 - 4.6e-25 88.5 0.4 5.5e-25 88.3 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP86243.1 - 2.7e-12 47.0 0.3 3.9e-12 46.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP86243.1 - 8.7e-08 31.9 0.3 1.3e-07 31.3 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP86243.1 - 1.9e-05 24.6 0.1 2.9e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAP86243.1 - 0.00078 18.9 0.5 0.0025 17.3 0.5 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase SPX PF03105.19 GAP86244.1 - 1.2 8.9 7.7 1.5 8.7 7.7 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 GAP86244.1 - 2.8 7.0 11.0 3 6.9 11.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DIE2_ALG10 PF04922.12 GAP86245.1 - 4.3e-119 398.3 8.3 5.3e-119 398.0 8.3 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Clr5 PF14420.6 GAP86246.1 - 1.5e-18 66.7 3.0 5.1e-18 65.0 0.6 2.3 2 0 0 2 2 2 1 Clr5 domain DHO_dh PF01180.21 GAP86247.1 - 7.5e-09 35.2 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase IMUP PF15761.5 GAP86247.1 - 0.02 15.6 12.9 0.35 11.6 7.4 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF3446 PF11928.8 GAP86247.1 - 0.031 14.6 2.5 0.031 14.6 2.5 2.7 2 1 0 2 2 2 0 Early growth response N-terminal domain Pap_E4 PF02711.14 GAP86247.1 - 0.056 14.4 0.8 1.5 9.8 0.1 2.2 2 0 0 2 2 2 0 E4 protein MCLC PF05934.11 GAP86247.1 - 0.18 10.5 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) SR-25 PF10500.9 GAP86247.1 - 0.54 9.8 18.0 0.3 10.7 9.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 GAP86247.1 - 0.69 10.2 15.6 3.2 8.0 10.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF4692 PF15763.5 GAP86247.1 - 1.8 9.0 8.8 3.8 8.0 3.2 2.1 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DHO_dh PF01180.21 GAP86248.1 - 5.8e-39 134.0 0.4 2e-25 89.6 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.17 GAP86248.1 - 0.0022 17.5 0.9 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.18 GAP86248.1 - 0.016 14.3 4.2 0.033 13.2 4.1 1.7 1 1 0 1 1 1 0 FMN-dependent dehydrogenase Ank_2 PF12796.7 GAP86249.1 - 6.2e-79 260.6 3.3 3.5e-14 53.1 0.1 8.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP86249.1 - 1e-67 223.7 2.5 9.7e-10 38.8 0.0 11.5 3 2 10 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.30 GAP86249.1 - 3.8e-57 188.4 27.0 8.5e-05 22.8 0.2 14.9 15 0 0 15 15 15 11 Ankyrin repeat Ank_3 PF13606.6 GAP86249.1 - 2.4e-43 141.1 6.4 0.009 16.5 0.0 14.8 14 1 1 15 15 15 10 Ankyrin repeat Ank_5 PF13857.6 GAP86249.1 - 3.1e-42 142.1 8.4 1.2e-06 28.7 0.0 10.4 5 3 5 10 10 10 8 Ankyrin repeats (many copies) NACHT PF05729.12 GAP86249.1 - 5.6e-06 26.4 0.1 1.3e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP86249.1 - 0.00013 22.4 0.1 0.00049 20.5 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain TTc_toxin_rep PF18807.1 GAP86249.1 - 0.0044 16.8 1.0 3.4 7.6 0.0 4.1 4 0 0 4 4 4 1 Tripartite Tc toxins repeat RNA_helicase PF00910.22 GAP86249.1 - 0.058 13.8 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase HET-s_218-289 PF11558.8 GAP86249.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Het-s 218-289 Med4 PF10018.9 GAP86250.1 - 7.2e-37 127.0 8.3 7.2e-37 127.0 8.3 1.4 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 SART-1 PF03343.13 GAP86250.1 - 0.00013 20.7 9.3 0.00016 20.4 9.3 1.1 1 0 0 1 1 1 1 SART-1 family Rrn6 PF10214.9 GAP86250.1 - 0.22 10.0 10.4 0.27 9.7 10.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor EMP70 PF02990.16 GAP86251.1 - 1.2e-204 680.8 3.8 1.7e-204 680.3 3.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Sas10_Utp3 PF04000.15 GAP86252.1 - 2.8e-15 56.7 0.5 2.8e-15 56.7 0.5 1.7 2 0 0 2 2 1 1 Sas10/Utp3/C1D family Sporozoite_P67 PF05642.11 GAP86252.1 - 0.0093 14.1 3.2 0.013 13.6 3.2 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CDV3 PF15359.6 GAP86252.1 - 0.041 14.4 5.8 0.088 13.3 5.8 1.6 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 CCDC106 PF15794.5 GAP86252.1 - 0.063 13.0 3.3 0.15 11.8 3.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PPP4R2 PF09184.11 GAP86252.1 - 0.29 10.7 6.2 0.42 10.2 6.2 1.3 1 0 0 1 1 1 0 PPP4R2 FAM176 PF14851.6 GAP86252.1 - 0.44 10.2 5.8 1.3 8.7 5.8 1.9 1 0 0 1 1 1 0 FAM176 family Pes-10 PF07149.11 GAP86252.1 - 0.49 9.4 6.0 0.66 9.0 6.0 1.1 1 0 0 1 1 1 0 Pes-10 GCIP PF13324.6 GAP86252.1 - 0.58 9.7 3.8 0.98 9.0 3.8 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF913 PF06025.12 GAP86252.1 - 0.84 8.6 2.2 1.2 8.1 1.3 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 GAP86252.1 - 0.9 7.6 14.8 1.2 7.2 14.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 GAP86252.1 - 1.1 8.5 15.1 1.9 7.7 15.1 1.3 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 GAP86252.1 - 1.1 9.2 9.5 2.7 8.0 9.5 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 GAP86252.1 - 1.6 7.8 22.1 0.016 14.4 14.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 GAP86252.1 - 2.5 6.2 18.0 0.019 13.2 10.3 1.3 2 0 0 2 2 2 0 Nop14-like family CENP-B_dimeris PF09026.10 GAP86252.1 - 2.6 8.5 20.0 5.8 7.4 20.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CNDH2_C PF16858.5 GAP86252.1 - 3.3 7.5 8.4 1.5 8.7 3.6 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 GAP86252.1 - 4.8 5.3 19.5 8.2 4.6 19.6 1.3 1 1 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 GAP86252.1 - 7.3 5.0 9.4 11 4.5 9.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Dicty_REP PF05086.12 GAP86252.1 - 8.6 4.2 6.1 11 3.9 6.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pyr_redox_3 PF13738.6 GAP86253.1 - 5.3e-16 58.7 0.1 1.8e-15 57.0 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP86253.1 - 8.7e-13 48.2 0.0 1e-11 44.6 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAP86253.1 - 1.6e-12 46.7 0.0 5.2e-12 45.0 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAP86253.1 - 1.1e-08 34.7 0.1 6.3e-07 28.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAP86253.1 - 2.3e-06 27.7 0.5 1.9e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAP86253.1 - 0.00011 22.6 2.9 0.047 14.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAP86253.1 - 0.00026 20.4 0.1 0.041 13.2 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 GAP86253.1 - 0.00029 20.9 0.1 0.19 11.8 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 GAP86253.1 - 0.00079 19.1 5.5 0.0014 18.3 5.0 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 GAP86253.1 - 0.0061 16.5 0.3 0.011 15.6 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 GAP86253.1 - 0.0093 16.0 2.6 0.059 13.4 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAP86253.1 - 0.012 15.0 0.6 0.025 14.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP86253.1 - 0.017 14.2 1.0 0.017 14.2 1.0 1.7 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 GAP86253.1 - 0.042 13.2 0.1 5.8 6.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 GAP86253.1 - 0.047 12.4 3.3 0.1 11.2 0.4 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 GAP86253.1 - 0.079 13.4 0.0 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 GAP86253.1 - 0.1 12.8 0.7 1.9 8.7 0.1 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 GAP86253.1 - 0.26 10.3 4.1 0.08 12.0 0.9 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 GAP86253.1 - 1 8.6 2.7 1.6 7.9 0.3 2.0 2 0 0 2 2 2 0 Thi4 family WD40 PF00400.32 GAP86254.1 - 1.2e-62 206.3 58.9 9.6e-11 42.1 0.4 12.6 13 0 0 13 13 13 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP86254.1 - 5.6e-22 77.9 9.0 0.029 14.7 0.1 10.0 3 2 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 GAP86254.1 - 1.9e-16 60.8 0.4 3.3e-16 60.0 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nucleoporin_N PF08801.11 GAP86254.1 - 4.5e-11 42.2 19.0 0.41 9.3 0.0 8.2 2 2 6 8 8 8 5 Nup133 N terminal like Nup160 PF11715.8 GAP86254.1 - 3.3e-09 35.9 13.8 0.25 10.0 0.2 7.1 3 2 6 9 9 9 5 Nucleoporin Nup120/160 NACHT PF05729.12 GAP86254.1 - 1.4e-06 28.3 0.1 2.6e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 GAP86254.1 - 1.9e-06 27.4 0.1 0.041 13.2 0.0 4.4 2 1 3 5 5 5 1 WD40-like domain AAA_16 PF13191.6 GAP86254.1 - 5.9e-06 26.8 0.0 1.8e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Ge1_WD40 PF16529.5 GAP86254.1 - 8.4e-05 21.7 11.8 14 4.5 0.0 8.3 4 2 3 7 7 7 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAP86254.1 - 0.0004 20.2 20.4 0.16 12.0 0.3 8.3 10 0 0 10 10 9 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 GAP86254.1 - 0.0016 17.0 0.7 0.2 10.2 0.0 3.1 3 0 0 3 3 3 1 Cytochrome D1 heme domain AAA_22 PF13401.6 GAP86254.1 - 0.024 14.9 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 GAP86254.1 - 0.083 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 GAP86254.1 - 0.095 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAP86254.1 - 0.15 12.6 0.3 0.45 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain RicinB_lectin_2 PF14200.6 GAP86254.1 - 0.54 11.0 6.8 0.27 12.0 0.5 3.4 3 1 1 4 4 4 0 Ricin-type beta-trefoil lectin domain-like CHORD PF04968.12 GAP86256.1 - 1.8e-48 163.0 19.9 1.3e-24 86.6 6.9 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 GAP86256.1 - 2.6e-11 44.3 0.0 4e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 CS domain HpcH_HpaI PF03328.14 GAP86257.1 - 2.9e-31 108.3 0.0 3.7e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 GAP86257.1 - 0.14 11.6 1.2 8.3 5.8 0.0 2.6 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase Fungal_trans PF04082.18 GAP86258.1 - 6.1e-11 41.9 0.1 8.6e-11 41.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP86258.1 - 7.6e-09 35.6 9.1 7.6e-09 35.6 9.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 GAP86259.1 - 8.6e-16 58.1 0.1 1.7e-15 57.1 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP86259.1 - 6.9e-09 35.7 0.2 0.00032 20.4 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAP86259.1 - 3.3e-06 27.6 0.0 0.00013 22.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP86259.1 - 7.1e-06 25.5 0.0 0.00023 20.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP86259.1 - 0.026 14.8 0.1 0.06 13.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAP86259.1 - 0.037 12.9 0.2 2.3 7.0 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 GAP86259.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Mg_trans_NIPA PF05653.14 GAP86260.1 - 2.8e-87 292.6 27.3 3.7e-87 292.2 27.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 GAP86260.1 - 5.5e-05 23.4 41.3 7.7e-05 22.9 9.2 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF5435 PF17503.2 GAP86260.1 - 0.059 13.1 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5435) PPP4R2 PF09184.11 GAP86260.1 - 0.17 11.4 2.9 0.33 10.5 2.9 1.4 1 0 0 1 1 1 0 PPP4R2 DUF5362 PF17319.2 GAP86260.1 - 3.4 7.6 8.1 0.58 10.0 0.1 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5362) NOA36 PF06524.12 GAP86260.1 - 3.7 6.8 9.6 6 6.1 9.6 1.2 1 0 0 1 1 1 0 NOA36 protein Acetyltransf_2 PF00797.17 GAP86262.1 - 2.9e-28 99.3 0.0 3.7e-27 95.7 0.0 2.1 2 0 0 2 2 2 1 N-acetyltransferase SGTA_dimer PF16546.5 GAP86263.1 - 3.9e-26 90.6 0.5 7.2e-26 89.8 0.5 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 GAP86263.1 - 1.2e-10 40.6 6.9 0.0041 17.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAP86263.1 - 4e-10 39.1 4.2 0.0044 16.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAP86263.1 - 8.2e-07 29.6 12.8 9.9e-06 26.1 7.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAP86263.1 - 2.8e-06 27.7 8.3 0.029 15.2 4.6 3.9 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAP86263.1 - 3.4e-06 26.6 4.4 0.0015 18.1 1.1 2.7 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 GAP86263.1 - 1.8e-05 24.8 1.1 0.025 14.9 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP86263.1 - 3.5e-05 23.7 3.1 2.5 8.5 0.5 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAP86263.1 - 3.5e-05 24.2 4.0 0.001 19.6 3.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat STI1 PF17830.1 GAP86263.1 - 0.00013 21.9 13.1 0.00057 19.8 7.3 2.6 2 0 0 2 2 2 1 STI1 domain TPR_12 PF13424.6 GAP86263.1 - 0.00096 19.4 4.7 0.0014 18.9 2.8 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat XPC-binding PF09280.11 GAP86263.1 - 0.0091 15.7 2.1 0.019 14.7 2.1 1.6 1 0 0 1 1 1 1 XPC-binding domain TPR_7 PF13176.6 GAP86263.1 - 0.0095 15.9 1.7 2.2 8.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAP86263.1 - 0.022 14.9 3.6 0.14 12.4 1.2 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAP86263.1 - 0.026 14.4 3.9 0.12 12.3 2.9 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SR-25 PF10500.9 GAP86263.1 - 0.051 13.2 2.8 0.082 12.5 2.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BTAD PF03704.17 GAP86263.1 - 0.055 13.9 2.3 7.7 6.9 0.0 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 GAP86263.1 - 0.072 13.8 5.7 10 7.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat GerD PF17898.1 GAP86263.1 - 1.3 9.0 4.9 2.4 8.2 1.6 2.4 1 1 0 1 1 1 0 Spore germination GerD central core domain ABC_tran PF00005.27 GAP86264.1 - 1.4e-31 109.8 0.0 5.1e-31 108.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 GAP86264.1 - 1.8e-18 67.2 3.3 1.8e-18 67.2 3.3 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 GAP86264.1 - 0.00011 21.7 0.0 0.0011 18.5 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain PAM2 PF07145.15 GAP86264.1 - 0.0083 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region RsgA_GTPase PF03193.16 GAP86264.1 - 0.0095 15.9 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 GAP86264.1 - 0.036 13.9 0.3 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 GAP86264.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 GAP86264.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.6 GAP86264.1 - 0.12 12.2 0.1 0.38 10.5 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 GAP86264.1 - 0.18 11.3 0.2 0.49 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain HD PF01966.22 GAP86265.1 - 0.0063 16.7 0.0 0.0091 16.2 0.0 1.3 1 0 0 1 1 1 1 HD domain PAN_4 PF14295.6 GAP86266.1 - 5e-05 23.1 2.0 5.7e-05 22.9 0.3 2.1 2 1 0 2 2 2 1 PAN domain PAN_1 PF00024.26 GAP86266.1 - 0.00094 19.1 0.1 0.0019 18.1 0.1 1.5 1 0 0 1 1 1 1 PAN domain Mucin PF01456.17 GAP86266.1 - 1.6 8.7 16.4 1.2 9.2 14.4 1.7 1 1 1 2 2 2 0 Mucin-like glycoprotein RhoGAP PF00620.27 GAP86267.1 - 6.4e-17 61.8 0.0 1.7e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain Helo_like_N PF17111.5 GAP86267.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF1481 PF07356.12 GAP86268.1 - 0.055 13.2 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) T2SSC PF11356.8 GAP86269.1 - 2 8.3 9.1 2.8 7.8 9.1 1.3 1 0 0 1 1 1 0 Type II secretion system protein C TFIIA PF03153.13 GAP86269.1 - 2.3 8.1 16.0 2.5 8.0 16.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4228 PF14009.6 GAP86269.1 - 5 7.5 9.4 3.1 8.2 7.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) zf-RING_2 PF13639.6 GAP86271.1 - 1.3e-08 35.0 9.3 3.1e-08 33.8 9.3 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 GAP86271.1 - 7.3e-06 26.1 9.0 2.4e-05 24.4 9.0 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 GAP86271.1 - 0.00025 21.0 2.4 0.00059 19.8 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 GAP86271.1 - 0.00065 19.9 8.4 0.0016 18.6 8.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain C1_1 PF00130.22 GAP86271.1 - 0.0019 18.0 3.9 0.0019 18.0 3.9 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.25 GAP86271.1 - 0.0024 17.7 10.6 0.0054 16.6 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 GAP86271.1 - 0.0041 17.2 8.3 0.012 15.8 8.3 1.9 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 GAP86271.1 - 0.012 15.3 5.6 0.029 14.0 5.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 GAP86271.1 - 0.036 13.9 6.2 0.088 12.7 6.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP86271.1 - 0.049 13.5 9.1 0.12 12.3 9.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 GAP86271.1 - 0.11 12.8 8.6 0.25 11.7 8.6 1.6 1 0 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 GAP86271.1 - 0.29 11.0 5.4 0.78 9.7 5.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_9 PF13901.6 GAP86271.1 - 0.37 10.7 7.1 1.1 9.2 7.1 1.8 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 GAP86271.1 - 1.3 9.2 3.8 3.6 7.8 3.8 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 GAP86271.1 - 2 8.4 7.8 4.1 7.4 7.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 GAP86271.1 - 2.6 8.1 6.2 6.4 6.9 6.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 GAP86271.1 - 8.5 6.3 7.9 1.7e+02 2.1 7.9 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Sigma70_r4 PF04545.16 GAP86272.1 - 0.077 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4210 PF13915.6 GAP86273.1 - 2.6e-33 114.4 0.6 6.9e-33 113.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 GAP86273.1 - 3.8e-23 81.4 0.4 7.4e-23 80.5 0.4 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.11 GAP86274.1 - 0.00049 20.2 17.7 0.043 13.8 0.1 2.6 2 1 0 2 2 2 2 rRNA processing SARAF PF06682.12 GAP86274.1 - 1.9 8.1 10.7 2.7 7.6 10.7 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1682 PF07946.14 GAP86274.1 - 6.9 5.8 8.5 11 5.1 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Kelch_5 PF13854.6 GAP86275.1 - 7.1e-13 48.2 8.5 2.6e-07 30.5 0.2 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 GAP86275.1 - 0.0033 17.3 1.8 11 6.2 0.0 5.4 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.6 GAP86275.1 - 0.59 10.5 14.8 4.5 7.7 0.9 6.0 6 0 0 6 6 6 0 Galactose oxidase, central domain Kelch_1 PF01344.25 GAP86275.1 - 2.9 7.5 11.6 28 4.4 0.0 5.4 7 0 0 7 7 7 0 Kelch motif RhoGAP PF00620.27 GAP86276.1 - 3.1e-47 160.2 3.0 2.4e-46 157.3 0.0 2.8 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.22 GAP86276.1 - 5.8e-14 52.1 19.1 3.3e-09 36.8 2.3 2.4 2 0 0 2 2 2 2 LIM domain KASH_CCD PF14662.6 GAP86276.1 - 0.0083 16.0 16.2 0.017 15.0 16.2 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 GAP86276.1 - 0.014 15.5 17.2 0.037 14.1 16.8 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 GAP86276.1 - 0.25 10.7 8.8 0.52 9.6 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 GAP86276.1 - 0.34 11.4 15.0 0.055 14.0 9.4 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Zn-ribbon_8 PF09723.10 GAP86276.1 - 5.8 7.1 20.4 0.86 9.8 1.3 4.0 3 1 1 4 4 4 0 Zinc ribbon domain Acetyltransf_10 PF13673.7 GAP86277.1 - 8.9e-09 35.4 0.1 1.8e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP86277.1 - 1.1e-08 35.4 0.0 2e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP86277.1 - 1.1e-06 28.9 0.0 1.5e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAP86277.1 - 1.6e-05 24.9 0.0 3.8e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 GAP86277.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAP86277.1 - 0.035 14.2 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAP86277.1 - 0.074 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ PPR_2 PF13041.6 GAP86278.1 - 5e-14 52.2 4.9 0.00017 21.7 0.0 7.5 6 3 4 10 10 10 3 PPR repeat family PPR PF01535.20 GAP86278.1 - 4.7e-13 48.4 0.7 0.008 16.4 0.0 7.0 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.6 GAP86278.1 - 8.1e-10 38.6 0.6 5.2e-05 23.2 0.0 4.3 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAP86278.1 - 4.5e-05 23.1 0.2 1.1 9.1 0.0 4.4 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 GAP86278.1 - 0.00027 20.4 0.2 1.4 8.2 0.0 3.4 1 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 GAP86278.1 - 0.00043 20.7 0.1 15 6.2 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAP86278.1 - 0.073 13.2 3.0 36 4.8 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAP86278.1 - 0.086 13.1 1.9 16 6.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAP86278.1 - 1.8 9.4 7.5 21 6.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAP86278.1 - 3.9 7.5 6.2 75 3.4 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP68 PF16969.5 GAP86279.1 - 1.3e-200 668.1 5.8 1.5e-200 668.0 5.8 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 HSP70 PF00012.20 GAP86280.1 - 9.4e-268 889.4 16.3 1.1e-267 889.2 16.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAP86280.1 - 1e-15 57.4 5.5 1.4e-13 50.3 2.2 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 GAP86280.1 - 0.00078 19.2 0.1 0.002 17.9 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 GAP86280.1 - 0.056 13.9 7.5 2.2 8.8 0.2 4.1 3 2 0 3 3 3 0 Cell division protein FtsA SMBP PF16785.5 GAP86280.1 - 0.062 13.5 2.2 0.19 12.0 2.2 1.9 1 0 0 1 1 1 0 Small metal-binding protein Ploopntkinase3 PF18751.1 GAP86280.1 - 0.063 13.2 0.1 0.81 9.6 0.0 2.4 1 1 0 2 2 2 0 P-loop Nucleotide Kinase3 Big_3_4 PF13754.6 GAP86280.1 - 0.15 11.8 0.0 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function EcoR124_C PF12008.8 GAP86280.1 - 5.3 6.6 11.2 1.2 8.7 7.9 1.6 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal DUF2415 PF10313.9 GAP86281.1 - 9e-15 54.3 0.0 1.9e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 GAP86281.1 - 0.00053 20.2 0.0 2.4 8.5 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAP86281.1 - 0.0013 19.5 2.6 0.58 11.1 0.1 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_3 PF13570.6 GAP86281.1 - 0.1 13.1 0.5 93 3.7 0.1 4.3 5 0 0 5 5 5 0 PQQ-like domain DAO PF01266.24 GAP86282.1 - 9.4e-33 114.2 14.8 8.1e-31 107.9 14.8 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP86282.1 - 0.0064 16.7 2.4 0.024 14.8 2.4 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pox_A_type_inc PF04508.12 GAP86283.1 - 0.013 15.3 0.4 0.032 14.1 0.4 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SlyX PF04102.12 GAP86283.1 - 0.05 14.2 12.3 1.1 9.9 5.0 2.4 2 0 0 2 2 2 0 SlyX DUF2046 PF09755.9 GAP86283.1 - 0.081 12.1 5.2 0.055 12.7 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DMSP_lyase PF16867.5 GAP86283.1 - 0.16 11.6 2.5 0.27 10.8 0.6 2.0 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase SKA2 PF16740.5 GAP86283.1 - 0.52 10.1 7.2 0.2 11.5 3.3 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 MFS_1 PF07690.16 GAP86284.1 - 2.2e-32 112.4 31.8 9.6e-28 97.1 9.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP86284.1 - 9e-08 31.4 8.0 9e-08 31.4 8.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 GAP86284.1 - 0.11 10.9 3.9 0.95 7.8 2.4 2.2 1 1 1 2 2 2 0 Transmembrane secretion effector Pkinase PF00069.25 GAP86285.1 - 6.9e-27 94.5 0.0 1.4e-26 93.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86285.1 - 4.5e-13 49.1 0.0 7.1e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ketoacyl-synt PF00109.26 GAP86286.1 - 6.3e-74 248.7 0.0 1.2e-73 247.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAP86286.1 - 1.3e-61 208.4 2.3 1.3e-60 205.2 0.1 2.8 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 GAP86286.1 - 1.2e-43 149.9 0.0 1.9e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP86286.1 - 2.5e-36 124.3 1.2 7.8e-36 122.7 0.3 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 GAP86286.1 - 5.8e-23 81.0 5.1 2.1e-11 44.0 0.2 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 GAP86286.1 - 1.1e-18 68.2 0.5 7.6e-18 65.5 0.1 2.6 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 GAP86286.1 - 1.1e-18 67.5 0.0 4.5e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase DUF2974 PF11187.8 GAP86286.1 - 0.00055 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) KAsynt_C_assoc PF16197.5 GAP86286.1 - 0.0018 18.7 0.0 0.0061 17.0 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 GAP86286.1 - 0.003 17.0 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain HMG_box_5 PF14887.6 GAP86286.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Abhydrolase_6 PF12697.7 GAP86286.1 - 0.064 13.9 1.9 0.68 10.5 0.4 2.9 3 0 0 3 3 3 0 Alpha/beta hydrolase family COesterase PF00135.28 GAP86287.1 - 1.3e-71 242.1 0.0 1.1e-70 238.9 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP86287.1 - 0.004 17.1 9.2 0.02 14.7 0.3 3.0 4 0 0 4 4 4 2 alpha/beta hydrolase fold PGI PF00342.19 GAP86288.1 - 1.3e-227 756.2 0.1 1.5e-227 756.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.25 GAP86289.1 - 8e-71 238.5 0.0 1e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86289.1 - 5.9e-35 120.8 0.0 8e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 GAP86289.1 - 2.4e-09 37.7 5.0 7.5e-09 36.2 5.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 GAP86289.1 - 1.6e-06 27.4 0.0 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAP86289.1 - 0.0072 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.30 GAP86289.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 C2 domain FTA2 PF13095.6 GAP86289.1 - 0.075 12.6 0.1 0.78 9.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAP86289.1 - 0.18 11.1 0.1 0.34 10.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3176 PF11374.8 GAP86290.1 - 3.4e-33 114.0 1.3 3.4e-33 114.0 1.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) PagP PF07017.11 GAP86290.1 - 0.1 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP CcmD PF04995.14 GAP86290.1 - 1.5 8.9 9.5 2.8 8.1 0.6 3.4 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Exo5 PF09810.9 GAP86291.1 - 6.1e-129 430.7 0.0 7.9e-129 430.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 GAP86291.1 - 3.9e-06 27.0 0.0 9.2e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily GATA PF00320.27 GAP86291.1 - 5 6.8 10.5 0.56 9.9 2.4 2.4 2 0 0 2 2 2 0 GATA zinc finger Glyco_hydr_30_2 PF14587.6 GAP86292.1 - 2.3e-14 53.8 0.3 2.7e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 GAP86292.1 - 1.1e-13 51.2 2.2 4.9e-13 49.1 2.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 GAP86292.1 - 1.3e-11 44.3 0.1 1.8e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30 PF02055.16 GAP86292.1 - 9.5e-11 41.2 0.1 2e-10 40.2 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain PfkB PF00294.24 GAP86292.1 - 0.025 13.9 4.9 0.047 13.0 4.9 1.4 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Acyl-CoA_dh_1 PF00441.24 GAP86293.1 - 4.2e-29 101.7 2.2 6.9e-29 101.0 2.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAP86293.1 - 6.3e-21 74.4 0.0 1.1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAP86293.1 - 5.1e-15 56.1 0.0 2.3e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 GAP86293.1 - 5.9e-06 26.6 0.5 1.1e-05 25.7 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4508 PF14969.6 GAP86294.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Glyco_hydro_31 PF01055.26 GAP86296.1 - 3.5e-105 352.7 0.1 5.4e-105 352.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 GAP86296.1 - 0.00012 22.3 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 GAP86296.1 - 0.0027 18.0 3.3 0.0055 17.0 0.1 2.8 2 1 0 2 2 2 1 Galactose mutarotase-like Ish1 PF10281.9 GAP86297.1 - 7.5e-86 282.1 17.2 1.4e-15 57.3 0.0 8.6 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 GAP86297.1 - 2.8e-08 33.3 0.0 13 5.7 0.0 7.7 10 0 0 10 10 10 2 SAP domain HeH PF12949.7 GAP86297.1 - 4.8e-07 29.4 0.3 6.3 6.6 0.0 6.0 7 0 0 7 7 7 3 HeH/LEM domain Slx4 PF09494.10 GAP86297.1 - 3e-06 27.1 1.6 5.7 7.0 0.0 6.3 5 1 1 6 6 6 1 Slx4 endonuclease Thymopoietin PF08198.11 GAP86297.1 - 0.021 14.4 0.0 1.6 8.4 0.0 3.5 4 0 0 4 4 4 0 Thymopoietin protein TubC_N PF18563.1 GAP86297.1 - 0.061 13.3 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 TubC N-terminal docking domain Filo_VP35 PF02097.15 GAP86297.1 - 0.071 12.2 0.0 14 4.6 0.0 3.3 3 1 0 4 4 4 0 Filoviridae VP35 SAM_2 PF07647.17 GAP86297.1 - 0.088 12.9 0.9 52 4.1 0.1 4.1 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) Mannosyl_trans3 PF11051.8 GAP86298.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Asp PF00026.23 GAP86299.1 - 7.6e-11 42.0 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 GAP86299.1 - 4.7e-05 22.7 1.0 9.4e-05 21.7 1.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain VSP PF03302.13 GAP86299.1 - 0.003 16.5 0.2 0.0049 15.8 0.2 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Rax2 PF12768.7 GAP86299.1 - 0.0093 15.4 0.0 0.038 13.4 0.0 2.0 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Podoplanin PF05808.11 GAP86299.1 - 0.029 14.5 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Podoplanin NmrA PF05368.13 GAP86301.1 - 1.5e-14 54.1 0.0 2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP86301.1 - 2.9e-10 40.4 0.0 6.1e-10 39.3 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAP86301.1 - 0.0011 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 GAP86301.1 - 0.027 14.7 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Skp1 PF01466.19 GAP86302.1 - 6.2e-19 67.9 0.3 1.3e-18 66.9 0.3 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GAP86302.1 - 9.5e-10 38.5 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Hen1_Lam_C PF18441.1 GAP86302.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Hen1 La-motif C-terminal domain HET PF06985.11 GAP86304.1 - 2.7e-11 44.0 1.6 4.7e-11 43.2 0.3 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4763 PF15960.5 GAP86305.1 - 0.039 13.3 0.5 0.084 12.2 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) HAD PF12710.7 GAP86306.1 - 2.9e-07 31.1 3.9 0.0087 16.5 0.4 2.8 2 2 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP86306.1 - 0.0054 17.0 0.2 0.47 10.7 0.2 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 GAP86306.1 - 0.0064 16.0 0.0 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 GAP86306.1 - 0.023 14.4 0.0 0.55 9.9 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_60s PF00428.19 GAP86306.1 - 0.16 12.6 2.1 0.49 11.0 0.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein TFIIF_beta_N PF17683.1 GAP86307.1 - 7.8e-30 104.3 0.3 7.8e-30 104.3 0.3 1.8 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 GAP86307.1 - 2.3e-27 94.9 1.6 4.1e-27 94.1 1.6 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Ofd1_CTDD PF10637.9 GAP86307.1 - 0.0097 15.3 1.9 0.0097 15.3 1.9 1.5 2 0 0 2 2 2 1 Oxoglutarate and iron-dependent oxygenase degradation C-term zf-CCCH PF00642.24 GAP86308.1 - 3.2e-07 30.1 19.4 0.011 15.6 0.5 4.7 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tli4_N PF18443.1 GAP86308.1 - 4e-05 24.0 1.6 0.054 13.9 0.3 2.4 2 0 0 2 2 2 2 Tle cognate immunity protein 4 N-terminal domain zf-CCCH_4 PF18044.1 GAP86308.1 - 0.0016 18.2 0.3 0.0016 18.2 0.3 3.5 3 1 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAP86308.1 - 0.0063 16.5 27.3 0.098 12.8 2.5 5.5 5 1 0 5 5 5 3 Zinc finger domain Torus PF16131.5 GAP86308.1 - 0.0063 17.2 13.6 0.4 11.4 0.2 3.9 2 1 2 4 4 4 2 Torus domain zf-CCCH_3 PF15663.5 GAP86308.1 - 0.021 15.1 8.2 0.038 14.2 0.4 2.6 1 1 1 2 2 2 0 Zinc-finger containing family zf-C3H1 PF10650.9 GAP86308.1 - 4.7 7.0 7.9 0.71 9.7 0.9 2.8 2 0 0 2 2 2 0 Putative zinc-finger domain Sel1 PF08238.12 GAP86309.1 - 9.6e-16 57.9 6.3 7.3e-05 23.3 0.7 4.6 5 0 0 5 5 5 3 Sel1 repeat UPF0561 PF10573.9 GAP86309.1 - 1.1 9.4 4.7 0.33 11.1 1.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 bZIP_1 PF00170.21 GAP86310.1 - 6.3e-09 35.8 13.6 1.6e-08 34.5 10.7 2.5 1 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 GAP86310.1 - 2.5e-05 24.2 8.2 2.5e-05 24.2 8.2 2.8 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAP86310.1 - 0.00022 21.7 16.6 0.00093 19.7 13.7 2.6 1 1 1 2 2 2 1 bZIP Maf transcription factor DUF737 PF05300.11 GAP86310.1 - 0.005 17.2 8.8 0.017 15.5 3.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF737) Fmp27_WPPW PF10359.9 GAP86310.1 - 0.016 14.1 8.3 0.03 13.2 8.3 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain KASH_CCD PF14662.6 GAP86310.1 - 0.045 13.6 13.0 0.091 12.6 13.0 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH OrfB_IS605 PF01385.19 GAP86310.1 - 0.11 12.7 3.0 0.23 11.7 3.0 1.5 1 0 0 1 1 1 0 Probable transposase FapA PF03961.13 GAP86310.1 - 1.1 7.8 8.1 1.6 7.3 8.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 GAP86310.1 - 1.3 9.2 17.8 4.1 7.6 15.6 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 GAP86310.1 - 2.6 7.3 11.9 4.5 6.5 8.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) MCU PF04678.13 GAP86310.1 - 4.7 7.3 7.3 58 3.7 4.6 2.6 2 1 0 2 2 2 0 Mitochondrial calcium uniporter CBF PF03914.17 GAP86312.1 - 3.4e-36 124.9 3.8 9.5e-36 123.4 0.6 2.5 2 1 0 2 2 2 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.14 GAP86313.1 - 4.9e-53 179.1 5.9 6e-53 178.8 5.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Rep_trans PF02486.19 GAP86313.1 - 0.055 13.2 2.1 0.072 12.8 1.4 1.5 1 1 0 1 1 1 0 Replication initiation factor Taxilin PF09728.9 GAP86313.1 - 0.057 12.6 7.6 0.07 12.3 7.6 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein rve_3 PF13683.6 GAP86313.1 - 0.11 12.3 0.3 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain HECT_2 PF09814.9 GAP86314.1 - 1.4e-82 277.5 0.4 4.4e-45 154.1 0.0 2.1 2 0 0 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Adipokin_hormo PF06377.11 GAP86314.1 - 0.12 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Adipokinetic hormone Questin_oxidase PF14027.6 GAP86315.1 - 2.5e-91 306.7 0.1 3.2e-91 306.4 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like Rad17 PF03215.15 GAP86316.1 - 6.4e-25 88.2 0.0 1.4e-24 87.0 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 GAP86316.1 - 0.00049 20.5 0.0 0.0043 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 GAP86316.1 - 0.00084 19.8 0.0 0.0023 18.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAP86316.1 - 0.0054 16.5 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAP86316.1 - 0.0064 16.8 0.0 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAP86316.1 - 0.031 14.6 0.5 0.12 12.7 0.5 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GAP86316.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 GAP86316.1 - 0.069 13.1 0.0 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 GAP86316.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 GAP86316.1 - 0.073 13.6 0.0 0.2 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAP86316.1 - 0.13 12.0 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF853 PF05872.12 GAP86316.1 - 0.14 10.8 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Peptidase_U4 PF03419.13 GAP86318.1 - 3.3 6.9 4.7 1.3 8.2 0.2 2.0 2 1 0 2 2 2 0 Sporulation factor SpoIIGA Phage_holin_3_6 PF07332.11 GAP86318.1 - 6.7 6.8 9.6 19 5.3 0.4 3.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Abhydrolase_3 PF07859.13 GAP86319.1 - 4.7e-41 141.0 0.0 6.2e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAP86319.1 - 7.4e-06 25.1 0.1 1.5e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 GAP86319.1 - 0.13 10.9 0.0 1.7 7.2 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 GAP86319.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) tRNA-synt_2 PF00152.20 GAP86320.1 - 8.2e-76 255.1 0.0 1.3e-75 254.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 GAP86320.1 - 1.3e-22 80.2 0.0 2.5e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 GAP86320.1 - 5.2e-09 36.0 0.0 3.3e-08 33.4 0.0 2.4 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAP86320.1 - 0.072 12.6 0.2 10 5.5 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) ABC2_membrane PF01061.24 GAP86321.1 - 1.7e-83 279.2 57.7 6.9e-43 146.5 22.0 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 GAP86321.1 - 7.5e-29 99.5 10.4 5.7e-24 83.8 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 GAP86321.1 - 5.4e-20 72.3 0.0 1.4e-16 61.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 GAP86321.1 - 8.9e-14 51.9 0.6 3.1e-13 50.1 0.6 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 GAP86321.1 - 6e-06 25.6 23.1 5.7e-05 22.4 8.2 2.7 2 0 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 GAP86321.1 - 0.057 12.9 0.1 0.24 10.8 0.0 1.9 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 GAP86321.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system F-box-like PF12937.7 GAP86322.1 - 0.0099 15.8 0.5 0.0099 15.8 0.5 2.4 3 0 0 3 3 3 1 F-box-like MFS_1 PF07690.16 GAP86323.1 - 2.1e-35 122.3 27.1 2.1e-35 122.3 27.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP86323.1 - 6.6e-13 48.3 10.8 7.3e-13 48.2 8.2 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAP86323.1 - 3.1e-08 32.5 9.1 2e-07 29.8 6.0 2.1 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Pre-PUA PF17832.1 GAP86324.1 - 3.2e-22 79.0 0.3 4.4e-22 78.6 0.3 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 GAP86324.1 - 9.9e-13 47.9 0.1 2.2e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 PUA domain PetG PF02529.15 GAP86325.1 - 0.0079 16.0 2.8 0.0079 16.0 2.8 1.6 2 0 0 2 2 2 1 Cytochrome B6-F complex subunit 5 TPT PF03151.16 GAP86326.1 - 1.1e-26 93.9 26.1 1.3e-26 93.6 26.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 GAP86326.1 - 0.0006 19.1 23.3 0.0057 15.9 23.3 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAP86326.1 - 0.035 14.3 38.9 0.12 12.5 10.7 3.0 3 0 0 3 3 3 0 EamA-like transporter family NST1 PF13945.6 GAP86327.1 - 1.3e-46 159.1 12.1 1.3e-46 159.1 12.1 5.3 3 2 2 5 5 5 1 Salt tolerance down-regulator Ras PF00071.22 GAP86328.1 - 5.8e-49 165.8 0.0 6.7e-49 165.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP86328.1 - 1e-21 77.3 0.0 1.4e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP86328.1 - 2.2e-06 27.3 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAP86328.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 GAP86328.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 GAP86328.1 - 0.092 12.5 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 GAP86328.1 - 0.22 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MRP-L28 PF09812.9 GAP86329.1 - 1e-07 32.2 0.3 2.9e-07 30.7 0.3 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 TPR_19 PF14559.6 GAP86332.1 - 0.015 15.8 0.2 11 6.6 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Fusion_gly PF00523.18 GAP86335.1 - 0.73 8.0 2.4 0.98 7.6 2.4 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Methyltransf_16 PF10294.9 GAP86336.1 - 1.1e-11 44.8 0.0 2.2e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase AMP-binding PF00501.28 GAP86338.1 - 3.4e-93 312.6 0.0 4.8e-93 312.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CdhD PF03599.16 GAP86338.1 - 0.0052 15.6 0.0 0.0087 14.8 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit AMP-binding_C PF13193.6 GAP86338.1 - 0.037 15.0 0.0 0.1 13.6 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain EF-hand_7 PF13499.6 GAP86339.1 - 3.3e-25 88.3 8.9 2.8e-16 59.7 1.3 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GAP86339.1 - 1.5e-24 83.7 5.1 3.8e-06 26.4 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 GAP86339.1 - 3e-24 82.7 14.3 3.2e-08 32.5 0.2 4.8 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 GAP86339.1 - 2.6e-17 61.5 14.1 3.8e-05 23.0 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 GAP86339.1 - 6.6e-14 51.5 13.0 3e-05 23.8 1.0 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 GAP86339.1 - 3.8e-09 36.4 8.5 0.0046 16.9 0.2 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 GAP86339.1 - 5.7e-05 23.4 0.7 0.0086 16.4 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAP86339.1 - 0.00076 19.8 3.6 0.84 10.0 0.5 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 GAP86339.1 - 0.02 13.8 0.6 2 7.2 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Staphylokinase PF02821.16 GAP86339.1 - 0.08 13.4 0.0 20 5.6 0.0 2.5 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family EF-hand_14 PF17959.1 GAP86339.1 - 0.13 12.6 3.1 6.8 7.1 0.0 3.6 3 1 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.6 GAP86339.1 - 0.19 11.6 5.7 0.44 10.4 0.1 3.6 5 0 0 5 5 5 0 EF hand Caleosin PF05042.13 GAP86339.1 - 0.23 11.4 2.7 36 4.2 0.0 3.5 2 1 2 4 4 4 0 Caleosin related protein CDC45 PF02724.14 GAP86340.1 - 2.8e-251 835.4 0.6 2.3e-249 829.0 0.6 3.0 1 1 0 1 1 1 1 CDC45-like protein CSRNP_N PF16019.5 GAP86340.1 - 0.092 12.6 1.4 0.21 11.5 1.4 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus FAM60A PF15396.6 GAP86340.1 - 1.1 9.2 7.7 0.054 13.5 1.7 1.7 2 0 0 2 2 2 0 Protein Family FAM60A DUF2201_N PF13203.6 GAP86340.1 - 1.9 8.0 9.4 1.3 8.6 2.2 2.4 2 0 0 2 2 2 0 Putative metallopeptidase domain Trypan_PARP PF05887.11 GAP86340.1 - 6.8 6.7 22.3 0.015 15.3 5.6 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SAPS PF04499.15 GAP86340.1 - 8.1 5.1 6.7 0.35 9.6 0.4 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Cupin_8 PF13621.6 GAP86341.1 - 5.1e-31 108.3 0.0 7.5e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAP86341.1 - 9.3e-08 31.9 0.0 2.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Peptidase_C36 PF05415.11 GAP86341.1 - 0.0087 16.3 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Beet necrotic yellow vein furovirus-type papain-like endopeptidase GNAT_acetyltr_2 PF13718.6 GAP86341.1 - 0.0093 15.4 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 JmjC PF02373.22 GAP86341.1 - 0.014 15.8 0.0 0.058 13.8 0.0 1.9 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 GAP86341.1 - 0.018 14.8 0.2 0.077 12.7 0.0 2.1 2 0 0 2 2 2 0 Cupin domain HA2 PF04408.23 GAP86342.1 - 3.8e-23 81.8 0.0 3.8e-23 81.8 0.0 2.2 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAP86342.1 - 2.9e-21 75.6 0.0 5.7e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAP86342.1 - 5.2e-14 52.5 0.0 1.5e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 GAP86342.1 - 5e-12 46.0 0.8 1.1e-11 44.9 0.8 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 GAP86342.1 - 3.3e-06 27.4 0.0 9.6e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 GAP86342.1 - 7.3e-05 22.6 0.6 0.00028 20.7 0.6 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 GAP86342.1 - 0.00012 21.8 0.1 0.00044 20.0 0.1 1.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 GAP86342.1 - 0.00027 20.1 0.2 0.00069 18.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 GAP86342.1 - 0.0064 16.8 0.2 0.014 15.7 0.2 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 GAP86342.1 - 0.028 13.7 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 GAP86342.1 - 0.04 14.0 0.1 0.33 11.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAP86342.1 - 0.079 13.3 0.1 0.33 11.3 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain ABC_tran PF00005.27 GAP86342.1 - 0.1 13.1 0.0 0.79 10.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 GAP86342.1 - 0.11 12.7 0.0 0.36 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Pmp3 PF01679.17 GAP86343.1 - 2.7e-21 75.5 8.2 4.6e-21 74.7 8.2 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SRF-TF PF00319.18 GAP86344.1 - 0.29 10.6 1.1 0.63 9.6 1.1 1.5 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) SUV3_C PF12513.8 GAP86345.1 - 4.7e-19 68.1 0.9 8.9e-19 67.2 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 GAP86345.1 - 2.2e-15 56.2 0.2 4.6e-15 55.2 0.2 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 GAP86345.1 - 1e-09 38.7 0.0 2.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Alginate_lyase2 PF08787.11 GAP86346.1 - 5.8e-33 114.7 0.0 6.8e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Synaptobrevin PF00957.21 GAP86348.1 - 1.2e-30 105.1 0.4 1.8e-30 104.6 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 GAP86348.1 - 4.8e-28 97.0 0.0 8.9e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain MutL PF13941.6 GAP86349.1 - 0.073 11.6 0.0 0.079 11.5 0.0 1.0 1 0 0 1 1 1 0 MutL protein adh_short PF00106.25 GAP86350.1 - 2.3e-18 66.4 0.0 1.6e-17 63.7 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAP86350.1 - 3e-07 30.5 0.1 1e-06 28.8 0.0 1.9 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 GAP86350.1 - 7.6e-06 25.7 0.0 3.7e-05 23.4 0.0 2.2 2 2 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAP86350.1 - 7.8e-06 25.5 0.0 2.5e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAP86350.1 - 0.0089 15.2 2.6 0.29 10.2 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF2570 PF10828.8 GAP86350.1 - 0.01 15.7 2.5 0.021 14.6 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) NmrA PF05368.13 GAP86350.1 - 0.082 12.5 0.5 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 GAP86350.1 - 0.11 11.8 4.4 0.39 10.1 0.0 2.8 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase ABC_tran_Xtn PF12848.7 GAP86350.1 - 5.2 7.2 15.0 3.5 7.7 12.6 1.9 1 1 0 1 1 1 0 ABC transporter G-patch PF01585.23 GAP86351.1 - 4.4e-09 36.1 0.1 8.2e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 G-patch domain Sec1 PF00995.23 GAP86352.1 - 1.1e-120 404.6 0.0 1.3e-120 404.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Npa1 PF11707.8 GAP86354.1 - 3.1e-102 342.4 0.0 6.5e-102 341.4 0.0 1.6 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 GAP86354.1 - 6.7e-56 189.1 1.0 5.1e-55 186.2 0.0 2.8 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 DIM1 PF02966.16 GAP86355.1 - 1.8e-65 218.7 0.1 2.1e-65 218.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 MOR2-PAG1_N PF14222.6 GAP86356.1 - 7.4e-203 675.5 0.0 1.1e-202 674.8 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 GAP86356.1 - 1.7e-84 283.7 0.1 1.4e-83 280.7 0.0 2.7 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 GAP86356.1 - 1.7e-41 142.0 2.5 1.8e-19 69.0 0.0 3.2 1 1 2 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.7 GAP86356.1 - 0.0029 17.7 3.9 5.3 7.0 0.0 4.7 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAP86356.1 - 0.022 15.2 0.5 1 9.8 0.0 4.1 4 0 0 4 4 4 0 HEAT repeats HEAT PF02985.22 GAP86356.1 - 0.15 12.4 5.4 2.9 8.4 0.0 5.3 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 GAP86356.1 - 0.29 11.7 2.5 72 4.0 0.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat FAD_binding_1 PF00667.20 GAP86357.1 - 8.2e-66 221.8 0.0 1.3e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAP86357.1 - 3.5e-35 121.3 0.5 8.2e-35 120.1 0.5 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAP86357.1 - 1.4e-21 77.2 0.1 2e-20 73.5 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 GAP86357.1 - 0.11 12.7 0.1 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin domain Shikimate_DH PF01488.20 GAP86357.1 - 0.18 11.9 0.2 0.41 10.7 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 GAP86357.1 - 0.2 11.1 0.8 3.9 6.9 0.2 2.2 2 0 0 2 2 2 0 short chain dehydrogenase RRM_1 PF00076.22 GAP86358.1 - 9.1e-20 70.3 0.0 9.8e-10 38.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.22 GAP86359.1 - 1e-38 132.8 0.0 2.9e-26 92.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 GAP86359.1 - 4.9e-30 103.6 0.0 9.1e-30 102.7 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 GAP86359.1 - 6.5e-08 32.8 1.6 0.00025 21.0 1.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GAP86359.1 - 5.9e-05 22.5 0.1 0.0075 15.6 0.1 2.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PaaX PF07848.12 GAP86359.1 - 0.015 15.5 0.1 0.04 14.1 0.1 1.7 1 0 0 1 1 1 0 PaaX-like protein NOA36 PF06524.12 GAP86359.1 - 7 5.9 14.5 10 5.4 14.5 1.1 1 0 0 1 1 1 0 NOA36 protein RPN1_RPN2_N PF17781.1 GAP86360.1 - 1.2e-111 373.0 0.6 2.3e-111 372.1 0.6 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 GAP86360.1 - 5e-30 103.3 0.0 8.7e-30 102.5 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 GAP86360.1 - 5.2e-15 55.0 15.6 0.00011 22.4 0.1 8.2 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 GAP86360.1 - 5.6e-08 33.1 0.1 0.0011 19.3 0.0 3.6 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 GAP86360.1 - 0.11 13.0 0.2 9.6 6.8 0.1 3.1 1 1 1 2 2 2 0 HEAT-like repeat DUF848 PF05852.11 GAP86360.1 - 0.15 12.2 0.6 0.36 10.9 0.6 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) HAND PF09110.11 GAP86360.1 - 0.87 10.4 4.6 2.7 8.8 4.6 1.8 1 0 0 1 1 1 0 HAND IFRD PF05004.13 GAP86360.1 - 1.1 8.3 4.6 2.3 7.2 0.1 3.3 3 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) DEAD PF00270.29 GAP86361.1 - 1.3e-33 116.2 0.3 7e-33 113.9 0.1 2.3 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP86361.1 - 1.2e-22 80.4 0.0 6.5e-22 78.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 GAP86361.1 - 3.1e-21 75.4 0.9 3.1e-21 75.4 0.9 2.0 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 GAP86361.1 - 0.0085 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAP86361.1 - 0.029 14.3 0.1 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DnaJ PF00226.31 GAP86362.1 - 1.2e-13 51.0 1.6 1.9e-13 50.3 0.5 2.0 2 0 0 2 2 2 1 DnaJ domain Arm PF00514.23 GAP86363.1 - 0.00033 20.6 0.2 0.21 11.7 0.0 3.0 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 GAP86363.1 - 0.0013 19.3 0.1 4.7 7.9 0.0 3.7 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAP86363.1 - 0.0017 18.5 0.8 0.051 13.9 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat RTP1_C1 PF10363.9 GAP86363.1 - 0.096 12.9 0.1 4.4 7.5 0.2 3.4 3 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RPN2_C PF18004.1 GAP86363.1 - 0.18 11.7 0.9 0.35 10.8 0.9 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_EZ PF13513.6 GAP86363.1 - 0.36 11.4 4.0 7 7.3 0.0 3.9 4 1 0 4 4 4 0 HEAT-like repeat DUF202 PF02656.15 GAP86365.1 - 7.1e-15 55.2 0.4 7.1e-15 55.2 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PsbI PF02532.14 GAP86365.1 - 0.2 11.6 2.9 0.42 10.6 0.2 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DUF2427 PF10348.9 GAP86365.1 - 0.21 11.4 3.1 0.19 11.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) MatE PF01554.18 GAP86366.1 - 9.9e-61 204.1 30.7 6.5e-34 116.9 9.0 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAP86366.1 - 0.017 15.2 3.9 0.017 15.2 3.9 3.5 3 2 1 4 4 4 0 Polysaccharide biosynthesis C-terminal domain 60KD_IMP PF02096.20 GAP86366.1 - 1.1 9.1 4.7 0.62 9.9 0.7 2.5 1 1 1 2 2 2 0 60Kd inner membrane protein YbgT_YccB PF08173.11 GAP86366.1 - 1.6 8.9 9.4 0.21 11.8 2.7 3.2 3 0 0 3 3 3 0 Membrane bound YbgT-like protein NUDIX PF00293.28 GAP86367.1 - 2e-25 89.4 0.0 2.8e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_1 PF00583.25 GAP86368.1 - 4.8e-07 30.0 0.1 8.6e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP86368.1 - 6e-07 29.8 0.6 1.5e-06 28.5 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP86368.1 - 4.1e-06 26.9 0.2 1e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAP86368.1 - 1.4e-05 25.0 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP86368.1 - 0.00022 21.1 0.0 0.0007 19.5 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 GAP86368.1 - 0.016 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DnaB_bind PF10410.9 GAP86368.1 - 0.031 14.5 0.0 0.26 11.5 0.0 2.4 2 1 1 3 3 3 0 DnaB-helicase binding domain of primase SRA PF18491.1 GAP86368.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 SET and RING associated domain RPA_C PF08784.11 GAP86369.1 - 6.5e-18 65.3 0.0 1.3e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 GAP86369.1 - 2.9e-08 33.6 0.1 6e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 GAP86369.1 - 0.00047 20.0 0.0 0.00091 19.1 0.0 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Ntox47 PF15540.6 GAP86369.1 - 0.07 13.4 0.4 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial toxin 47 Lon_C PF05362.13 GAP86370.1 - 1.5e-62 210.8 0.1 2.7e-62 210.0 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 GAP86370.1 - 1.1e-22 80.9 0.1 4.5e-22 78.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 GAP86370.1 - 1.6e-22 80.4 0.0 4.2e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 GAP86370.1 - 3.2e-08 33.7 0.0 1e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 GAP86370.1 - 6e-08 32.6 0.1 8.9e-07 28.8 0.0 2.4 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase RuvB_N PF05496.12 GAP86370.1 - 1.5e-06 28.0 0.3 7.9e-06 25.7 0.0 2.2 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAP86370.1 - 3.9e-06 27.4 0.0 1.4e-05 25.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.11 GAP86370.1 - 7.6e-05 22.6 0.0 0.00024 21.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAP86370.1 - 0.00012 22.3 0.1 0.013 15.8 0.0 3.1 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 GAP86370.1 - 0.00017 20.9 0.0 0.00039 19.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 GAP86370.1 - 0.00019 21.6 0.0 0.00096 19.3 0.0 2.3 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 GAP86370.1 - 0.00021 21.1 0.0 0.0008 19.2 0.0 2.1 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 GAP86370.1 - 0.0029 17.7 0.0 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 GAP86370.1 - 0.0081 16.1 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 GAP86370.1 - 0.012 16.0 0.0 0.095 13.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 GAP86370.1 - 0.014 15.9 0.0 0.014 15.9 0.0 3.2 2 1 0 3 3 2 0 AAA domain AAA_33 PF13671.6 GAP86370.1 - 0.015 15.4 0.1 0.047 13.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 GAP86370.1 - 0.03 14.9 0.0 0.085 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAP86370.1 - 0.033 13.6 0.3 0.17 11.2 0.1 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 GAP86370.1 - 0.035 14.0 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 GAP86370.1 - 0.043 13.7 0.0 0.76 9.6 0.0 2.7 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_PrkA PF08298.11 GAP86370.1 - 0.057 12.3 0.0 0.42 9.5 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain KinB_sensor PF16767.5 GAP86370.1 - 0.1 13.1 0.3 0.24 11.9 0.3 1.6 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB TsaE PF02367.17 GAP86370.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 GAP86370.1 - 0.13 11.5 0.6 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 GAP86370.1 - 0.14 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 GAP86370.1 - 0.15 11.8 0.1 0.62 9.8 0.0 2.1 3 0 0 3 3 2 0 AAA domain CbiA PF01656.23 GAP86370.1 - 0.18 11.9 0.4 1.3 9.1 0.1 2.4 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 GAP86370.1 - 0.2 12.2 1.5 2.1 8.8 0.0 3.2 3 1 0 3 3 2 0 ABC transporter Ino80_Iec3 PF14612.6 GAP86370.1 - 0.29 11.8 2.8 0.55 10.8 2.8 1.4 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling CENP-X PF09415.10 GAP86370.1 - 0.58 10.5 3.1 0.77 10.1 0.2 2.6 2 0 0 2 2 2 0 CENP-S associating Centromere protein X SOBP PF15279.6 GAP86371.1 - 2.8 8.5 7.9 3.4 8.2 7.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Zn_clus PF00172.18 GAP86373.1 - 1e-06 28.8 10.9 1.6e-06 28.1 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ISET-FN3_linker PF16625.5 GAP86374.1 - 2.5 8.7 10.8 2.1 9.0 1.2 3.1 3 0 0 3 3 3 0 Unstructured linking region I-set and fnIII on Brother of CDO Mlh1_C PF16413.5 GAP86375.1 - 4.3e-99 331.3 0.0 1.2e-98 329.8 0.0 1.7 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 GAP86375.1 - 3.6e-33 113.8 0.0 6.5e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAP86375.1 - 3.6e-13 49.5 0.0 8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAP86375.1 - 4.9e-07 30.2 0.0 1.2e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Myb_DNA-binding PF00249.31 GAP86376.1 - 0.037 14.2 0.2 0.037 14.2 0.2 2.0 2 1 0 2 2 2 0 Myb-like DNA-binding domain PDZ_1 PF12812.7 GAP86377.1 - 6.7e-51 170.2 0.0 9e-33 112.1 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 GAP86377.1 - 6.1e-24 85.6 2.5 1.7e-20 74.5 0.1 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 GAP86377.1 - 8.2e-15 54.9 0.5 1.4e-06 28.5 0.0 4.6 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 GAP86377.1 - 1.7e-14 53.4 0.3 4.5e-06 26.4 0.1 4.1 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 GAP86377.1 - 6.1e-12 45.7 0.0 6.7e-06 26.4 0.0 3.8 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 GAP86377.1 - 0.0001 22.2 1.0 0.014 15.3 0.3 3.5 3 0 0 3 3 3 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 GAP86377.1 - 0.09 12.5 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 GAP86377.1 - 0.12 11.0 0.3 0.26 9.9 0.1 1.5 2 0 0 2 2 2 0 Peptidase S46 Endomucin PF07010.12 GAP86378.1 - 0.058 13.4 29.7 0.076 13.0 29.7 1.1 1 0 0 1 1 1 0 Endomucin SOBP PF15279.6 GAP86378.1 - 0.72 10.4 9.3 1 9.9 9.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 GAP86378.1 - 6.3 3.8 7.9 7.2 3.6 7.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3827 PF12877.7 GAP86378.1 - 8.2 4.7 11.7 10 4.4 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) HsbA PF12296.8 GAP86379.1 - 3.2e-11 43.7 0.0 4.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Zn_clus PF00172.18 GAP86380.1 - 2.8e-09 37.0 9.6 2.8e-09 37.0 9.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_C PF00137.21 GAP86381.1 - 2.6e-27 94.9 28.9 2.5e-15 56.5 11.2 2.2 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 GAP86381.1 - 0.032 13.5 0.4 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 tRNA_bind PF01588.20 GAP86382.1 - 8.2e-22 77.1 0.3 2.6e-21 75.5 0.3 1.9 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 GAP86382.1 - 0.00061 19.8 0.0 0.0018 18.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAP86382.1 - 0.0046 17.2 0.8 0.034 14.4 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain TRM PF02005.16 GAP86383.1 - 0.29 10.3 0.8 0.39 9.8 0.8 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase RNA_pol PF00940.19 GAP86384.1 - 1.2e-185 617.3 0.0 1.5e-185 616.9 0.0 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 GAP86384.1 - 1.5e-96 323.8 0.2 2.8e-96 322.8 0.2 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DUF5473 PF17567.2 GAP86384.1 - 4.3 7.7 7.8 5 7.5 1.6 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5473) RsfS PF02410.15 GAP86385.1 - 1.5e-10 41.4 0.0 6.3e-10 39.4 0.0 2.1 2 1 0 2 2 2 1 Ribosomal silencing factor during starvation DHHA2 PF02833.14 GAP86386.1 - 8.5e-29 100.6 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 GAP86386.1 - 7e-09 35.8 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 DHH family Pkinase PF00069.25 GAP86387.1 - 4e-23 82.1 0.0 6.2e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 GAP86387.1 - 5.8e-10 39.6 9.2 4.3e-07 30.5 0.1 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.22 GAP86387.1 - 2.3e-09 36.7 6.9 0.31 11.4 0.1 6.8 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 GAP86387.1 - 2.7e-05 24.5 2.4 0.2 12.1 0.0 5.1 4 1 1 5 5 5 1 HEAT repeats Pkinase_Tyr PF07714.17 GAP86387.1 - 3e-05 23.4 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 GAP86387.1 - 0.0038 17.3 0.0 4.1 7.4 0.0 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAP86387.1 - 0.0056 17.1 2.3 0.11 13.0 0.3 3.3 3 0 0 3 3 3 1 HEAT-like repeat SH3_9 PF14604.6 GAP86388.1 - 3.7e-06 26.7 0.1 9.3e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SARAF PF06682.12 GAP86388.1 - 6.9e-05 22.6 1.5 0.00015 21.5 1.5 1.6 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis SH3_1 PF00018.28 GAP86388.1 - 8.5e-05 22.1 0.1 0.00017 21.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Glycophorin_A PF01102.18 GAP86388.1 - 0.00055 20.2 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A TMEM51 PF15345.6 GAP86388.1 - 0.021 14.7 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 Syndecan PF01034.20 GAP86388.1 - 0.046 13.6 0.2 0.094 12.6 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain CD34_antigen PF06365.12 GAP86388.1 - 0.19 11.3 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family CbiM PF01891.16 GAP86388.1 - 0.43 10.4 2.0 0.93 9.3 2.0 1.4 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region TraT PF05818.12 GAP86388.1 - 1.5 8.5 3.9 13 5.4 0.1 2.3 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein FAM176 PF14851.6 GAP86390.1 - 0.057 13.1 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 FAM176 family Ribonucleas_3_3 PF14622.6 GAP86391.1 - 1.6e-08 34.8 0.0 0.0013 18.9 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 GAP86391.1 - 1e-05 26.1 0.0 4.8e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease III domain PLA2_B PF01735.18 GAP86392.1 - 3.7e-26 91.6 0.0 7.6e-26 90.6 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DUF4407 PF14362.6 GAP86392.1 - 0.67 9.2 4.9 1.8 7.9 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Phage_holin_2_4 PF16082.5 GAP86392.1 - 3.1 7.6 4.8 57 3.5 4.5 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Serglycin PF04360.12 GAP86392.1 - 3.9 7.4 6.2 8 6.4 6.2 1.4 1 0 0 1 1 1 0 Serglycin Acetyltransf_1 PF00583.25 GAP86394.1 - 0.0093 16.2 0.1 0.013 15.7 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP86394.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NOA36 PF06524.12 GAP86395.1 - 3 7.1 10.8 4.4 6.5 10.8 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 GAP86395.1 - 3.1 7.4 4.5 6.5 6.4 4.5 1.5 1 0 0 1 1 1 0 FAM176 family Pkinase PF00069.25 GAP86396.1 - 1.4e-34 119.7 0.0 1.7e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86396.1 - 2e-10 40.4 0.0 2.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP86396.1 - 0.033 14.1 0.0 0.53 10.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 GAP86396.1 - 0.053 12.8 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 GAP86396.1 - 0.055 13.1 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 GAP86396.1 - 0.088 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase muHD PF10291.9 GAP86397.1 - 6.7e-67 225.7 0.0 1e-66 225.1 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 GAP86397.1 - 6.6e-11 42.3 1.1 6.6e-11 42.3 1.1 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF922 PF06037.11 GAP86397.1 - 0.044 13.6 6.0 0.13 12.0 3.4 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) P16-Arc PF04699.14 GAP86397.1 - 0.27 11.7 5.3 0.97 9.9 0.1 2.8 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) V_ATPase_I PF01496.19 GAP86397.1 - 0.9 7.4 6.9 1.4 6.7 6.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EMC3_TMCO1 PF01956.16 GAP86397.1 - 1.4 8.6 5.5 3.3 7.4 5.5 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF883 PF05957.13 GAP86397.1 - 1.6 9.4 10.8 13 6.5 3.6 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Snapin_Pallidin PF14712.6 GAP86397.1 - 5.5 7.5 7.3 0.7 10.4 1.7 2.4 3 0 0 3 3 3 0 Snapin/Pallidin MAD PF05557.13 GAP86398.1 - 1.6e-63 215.2 67.3 1.8e-62 211.7 66.9 1.9 1 1 1 2 2 2 2 Mitotic checkpoint protein Tam41_Mmp37 PF09139.11 GAP86399.1 - 1.3e-128 429.0 0.0 1.6e-128 428.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Aldo_ket_red PF00248.21 GAP86400.1 - 5.5e-73 245.7 0.0 6.2e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldedh PF00171.22 GAP86402.1 - 7.5e-59 199.4 2.3 1.1e-33 116.5 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Aldedh PF00171.22 GAP86403.1 - 3.5e-33 114.8 0.0 3.8e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cellulase PF00150.18 GAP86404.1 - 1.3e-33 116.7 0.6 2e-33 116.1 0.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 GAP86404.1 - 3.2e-21 75.2 2.6 3.7e-20 71.8 2.6 2.7 2 0 0 2 2 2 1 Carbohydrate binding domain X2 CHB_HEX_C_1 PF13290.6 GAP86404.1 - 0.048 13.7 0.4 0.14 12.1 0.4 1.9 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain tRNA-synt_1 PF00133.22 GAP86405.1 - 8.9e-34 116.7 0.0 7.4e-13 47.6 0.0 3.4 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 GAP86405.1 - 1e-15 57.4 0.2 3.2e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAP86405.1 - 1.9e-12 47.4 0.0 4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 GAP86405.1 - 1.2e-05 24.8 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Glyco_hydro_38 PF18438.1 GAP86406.1 - 0.081 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 Ank_2 PF12796.7 GAP86407.1 - 9.2e-29 99.9 0.0 1.4e-11 44.8 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP86407.1 - 4e-17 62.0 0.1 4.2e-08 33.3 0.0 5.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP86407.1 - 3.9e-15 54.4 0.2 0.008 16.6 0.0 8.2 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.6 GAP86407.1 - 1.1e-14 54.6 0.6 9.2e-07 29.3 0.1 5.7 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 GAP86407.1 - 5.1e-10 39.3 0.2 0.0062 16.9 0.0 6.6 6 1 0 6 6 6 2 Ankyrin repeat AAA_16 PF13191.6 GAP86407.1 - 1.3e-09 38.7 0.0 9.1e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GAP86407.1 - 7.8e-08 32.4 0.0 2.2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAP86407.1 - 0.00092 19.5 0.0 0.0094 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAP86407.1 - 0.037 13.2 0.0 0.085 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Scs3p PF10261.9 GAP86408.1 - 1.1e-38 133.2 0.2 1.3e-38 133.0 0.2 1.0 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Scs3p PF10261.9 GAP86409.1 - 6.7e-08 32.3 1.3 8.7e-08 32.0 0.4 1.5 2 0 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF3439 PF11921.8 GAP86409.1 - 0.0019 18.2 6.6 0.0027 17.6 6.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Auxin_repressed PF05564.12 GAP86409.1 - 0.21 12.3 7.2 0.3 11.8 5.0 1.9 2 0 0 2 2 2 0 Dormancy/auxin associated protein SSP160 PF06933.11 GAP86409.1 - 4.6 5.3 11.4 5.6 5.0 11.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pectate_lyase_3 PF12708.7 GAP86410.1 - 5.4e-93 310.8 18.5 2.8e-80 269.2 8.4 3.2 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAP86410.1 - 1.1e-05 25.1 2.5 0.03 14.0 0.3 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase RestrictionMunI PF11407.8 GAP86410.1 - 0.0033 17.2 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Type II restriction enzyme MunI MHB PF16525.5 GAP86410.1 - 0.04 14.2 0.0 3.8 7.8 0.0 2.7 2 0 0 2 2 2 0 Haemophore, haem-binding Bac_export_1 PF01311.20 GAP86410.1 - 0.12 11.9 0.2 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 Bacterial export proteins, family 1 Period_C PF12114.8 GAP86410.1 - 0.28 10.7 0.0 0.28 10.7 0.0 3.2 2 1 1 3 3 3 0 Period protein 2/3C-terminal region Glyco_hydro_1 PF00232.18 GAP86411.1 - 2.8e-149 497.4 0.1 3.4e-149 497.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 SBF_like PF13593.6 GAP86412.1 - 2.4e-81 273.5 16.5 2.9e-81 273.2 16.5 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Kei1 PF08552.11 GAP86412.1 - 0.066 13.1 0.5 0.64 9.9 0.0 2.4 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Orai-1 PF07856.12 GAP86412.1 - 0.93 9.1 4.5 0.19 11.4 0.2 2.0 2 0 0 2 2 2 0 Mediator of CRAC channel activity Pro-kuma_activ PF09286.11 GAP86413.1 - 1.2e-32 113.2 0.0 1.9e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAP86413.1 - 1e-07 31.5 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Rsm22 PF09243.10 GAP86414.1 - 0.016 14.5 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_31 PF13847.6 GAP86415.1 - 1.2e-10 41.3 0.0 2.7e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP86415.1 - 4.3e-05 24.2 0.0 0.0001 23.0 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP86415.1 - 7.6e-05 22.6 0.1 0.00016 21.6 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP86415.1 - 0.00039 21.1 0.0 0.0013 19.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP86415.1 - 0.00073 20.1 0.0 0.016 15.9 0.0 2.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAP86415.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 GAP86415.1 - 0.026 14.8 0.1 0.061 13.7 0.0 1.6 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase HEAT PF02985.22 GAP86416.1 - 6.8e-37 122.3 15.3 0.015 15.5 0.1 13.2 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 GAP86416.1 - 1e-34 118.8 4.1 7e-10 39.2 0.0 8.2 3 3 6 9 9 9 8 HEAT repeats Vac14_Fab1_bd PF12755.7 GAP86416.1 - 3.1e-11 43.7 2.8 0.021 15.4 0.2 7.5 5 2 4 9 9 9 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 GAP86416.1 - 3.2e-11 43.5 7.5 0.028 14.9 0.1 9.5 9 2 2 11 11 11 1 HEAT-like repeat Cnd1 PF12717.7 GAP86416.1 - 3.4e-09 36.9 12.7 0.015 15.3 0.1 5.9 4 2 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 GAP86416.1 - 2.5e-07 30.8 4.2 0.72 10.1 0.0 5.1 3 1 2 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 GAP86416.1 - 1.2e-05 24.1 9.4 0.037 12.6 2.4 4.6 3 1 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.8 GAP86416.1 - 0.00064 19.3 2.1 2.7 7.5 0.3 4.4 3 3 0 4 4 4 2 CLASP N terminal Proteasom_PSMB PF10508.9 GAP86416.1 - 0.0037 15.8 2.2 0.4 9.1 0.0 2.4 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit M11L PF11099.8 GAP86416.1 - 0.044 14.0 0.5 18 5.6 0.1 3.3 2 1 1 3 3 3 0 Apoptosis regulator M11L like Arm PF00514.23 GAP86416.1 - 0.074 13.1 5.3 2.7 8.1 0.0 4.7 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat TetR_C_16 PF17920.1 GAP86416.1 - 0.092 13.0 0.2 60 3.9 0.0 3.7 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Ecm29 PF13001.7 GAP86416.1 - 0.24 10.0 3.0 11 4.6 0.0 3.7 4 1 1 5 5 5 0 Proteasome stabiliser Myotub-related PF06602.14 GAP86417.1 - 2e-146 487.5 0.0 2.4e-146 487.2 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 GAP86417.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_S3_C PF00189.20 GAP86418.1 - 3.4e-25 88.4 0.2 2.3e-24 85.7 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 GAP86418.1 - 6.1e-12 45.2 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 GAP86418.1 - 0.097 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 GAP86418.1 - 0.11 12.4 0.1 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Coilin N-terminus Mg_trans_NIPA PF05653.14 GAP86419.1 - 5.3e-103 344.2 13.0 6.5e-103 343.9 13.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 GAP86419.1 - 2e-05 24.8 6.2 2e-05 24.8 6.2 3.2 3 0 0 3 3 3 1 EamA-like transporter family DUF2420 PF10336.9 GAP86420.1 - 2.3e-09 37.2 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 GAP86421.1 - 1e-15 57.8 0.0 1.6e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAP86421.1 - 4e-09 36.5 0.1 6.5e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 GAP86421.1 - 0.008 16.6 0.3 0.015 15.7 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) ANAPC4 PF12896.7 GAP86422.1 - 3.6e-66 222.6 3.1 3.8e-66 222.5 2.1 1.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 GAP86422.1 - 1.5e-18 66.9 0.2 1.6e-17 63.5 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAP86422.1 - 0.015 16.2 0.1 0.15 13.0 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat UBX PF00789.20 GAP86422.1 - 0.085 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 UBX domain AMP-binding PF00501.28 GAP86423.1 - 1.8e-69 234.4 0.0 2.4e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP86423.1 - 1e-20 74.5 0.1 2.3e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain KTI12 PF08433.10 GAP86424.1 - 1.1e-66 225.1 0.0 1.6e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 GAP86424.1 - 7.5e-05 22.9 0.1 0.00015 22.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAP86424.1 - 0.0049 17.1 0.0 0.0085 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAP86424.1 - 0.011 16.3 0.0 0.051 14.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.18 GAP86424.1 - 0.04 13.2 0.0 0.071 12.4 0.0 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.6 GAP86424.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Gasdermin PF04598.12 GAP86424.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Gasdermin pore forming domain Pyr_redox_2 PF07992.14 GAP86425.1 - 2.1e-11 43.6 0.0 1.9e-09 37.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP86425.1 - 8.5e-10 38.4 0.0 1.6e-08 34.2 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAP86425.1 - 1e-08 34.1 0.0 3.6e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAP86425.1 - 1.8e-08 34.0 0.0 8.6e-06 25.1 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAP86425.1 - 1.9e-06 28.0 2.1 0.0099 15.9 0.0 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 GAP86425.1 - 0.0001 22.1 0.7 0.022 14.4 0.7 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP86425.1 - 0.00012 22.3 0.0 0.00028 21.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAP86425.1 - 0.0073 15.6 1.3 0.0095 15.2 0.1 1.7 2 0 0 2 2 2 1 Thi4 family SNF5 PF04855.12 GAP86427.1 - 3.7e-65 220.0 0.1 8.5e-64 215.6 0.1 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.24 GAP86428.1 - 0.00016 21.5 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4258 PF14076.6 GAP86428.1 - 0.0079 16.6 0.3 0.22 12.0 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4258) PHD PF00628.29 GAP86429.1 - 3.8e-13 49.1 23.7 4.4e-09 36.1 10.3 2.4 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 GAP86429.1 - 0.00038 19.9 8.3 0.036 13.6 4.5 2.8 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 GAP86429.1 - 0.002 17.7 8.6 0.01 15.5 1.4 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain ROQ_II PF18386.1 GAP86429.1 - 0.026 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Roquin II domain PUF PF00806.19 GAP86430.1 - 1.8e-27 93.4 0.0 3.8e-05 23.1 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 GAP86430.1 - 6.1e-13 48.4 0.0 1.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3439 PF11921.8 GAP86432.1 - 0.018 15.0 3.8 0.043 13.8 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pep3_Vps18 PF05131.14 GAP86433.1 - 5.7e-49 165.8 1.1 8.5e-49 165.2 0.3 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 GAP86433.1 - 2.1e-09 37.4 5.7 1.8e-07 31.1 0.1 3.4 3 1 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 GAP86433.1 - 0.00033 20.2 0.2 0.00073 19.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 GAP86433.1 - 0.00046 20.0 0.6 0.0011 18.8 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP86433.1 - 0.0046 16.9 1.8 0.0046 16.9 1.8 1.7 2 0 0 2 2 2 1 zinc-RING finger domain Vps39_2 PF10367.9 GAP86433.1 - 0.0054 17.2 0.1 0.018 15.5 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 GAP86433.1 - 0.0071 16.7 1.4 0.019 15.3 1.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 GAP86433.1 - 0.012 15.4 4.0 0.012 15.4 4.0 2.3 2 0 0 2 2 2 0 RING-like zinc finger DUF2175 PF09943.9 GAP86433.1 - 0.032 14.5 2.0 0.036 14.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_UBOX PF13445.6 GAP86433.1 - 0.037 14.0 1.9 0.087 12.9 1.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 GAP86433.1 - 0.043 14.1 0.2 0.12 12.7 0.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAP86433.1 - 2.7 7.9 5.6 0.45 10.4 1.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 GAP86433.1 - 5.7 7.1 6.8 1 9.5 2.7 1.9 2 0 0 2 2 2 0 Zinc-finger Methyltransf_23 PF13489.6 GAP86434.1 - 7e-17 61.7 0.1 5.9e-16 58.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP86434.1 - 8.9e-11 42.4 0.0 3.8e-10 40.4 0.0 2.1 2 1 1 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP86434.1 - 3e-09 36.8 0.0 3.7e-08 33.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP86434.1 - 4.7e-09 36.9 0.0 1.5e-08 35.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP86434.1 - 2.6e-08 34.4 0.0 7.7e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP86434.1 - 6.3e-05 22.4 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 GAP86434.1 - 0.00028 20.2 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 GAP86434.1 - 0.0022 17.5 0.0 0.0044 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 GAP86434.1 - 0.0048 16.2 0.1 0.0097 15.2 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 GAP86434.1 - 0.0059 16.2 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 GAP86434.1 - 0.037 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 GAP86435.1 - 1.5e-69 235.0 0.0 1.7e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAP86435.1 - 5e-55 186.6 0.1 6.3e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAP86435.1 - 2.7e-22 79.2 0.0 3e-21 75.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAP86435.1 - 8.7e-19 67.6 0.0 1.1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAP86435.1 - 6.8e-18 64.8 0.3 1.9e-16 60.1 0.3 2.3 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 GAP86435.1 - 5e-17 61.9 0.0 6.5e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 GAP86435.1 - 1.6e-07 31.4 0.0 4.8e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding TPT PF03151.16 GAP86436.1 - 1.8e-06 27.5 17.6 2.5e-06 27.0 17.6 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAP86436.1 - 5.1e-06 26.7 13.9 5.1e-06 26.7 13.9 2.3 2 0 0 2 2 2 1 EamA-like transporter family PX PF00787.24 GAP86437.1 - 7.1e-19 67.9 0.0 2e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 GAP86437.1 - 9.4e-14 51.5 10.2 9.9e-09 35.1 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 GAP86437.1 - 0.0014 18.2 0.4 0.025 14.1 0.2 2.2 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein ATP-synt_C PF00137.21 GAP86438.1 - 5.4e-26 90.7 27.6 1.1e-19 70.5 12.7 2.0 2 0 0 2 2 2 2 ATP synthase subunit C RELT PF12606.8 GAP86438.1 - 0.15 11.1 4.5 0.36 9.9 4.5 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 HET PF06985.11 GAP86439.1 - 2.5e-24 86.3 0.0 4.1e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_C PF05199.13 GAP86440.1 - 1.1e-07 32.4 0.0 1e-06 29.3 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Asp PF00026.23 GAP86441.1 - 3.6e-70 236.9 2.1 4.4e-70 236.6 2.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP86441.1 - 1e-11 45.4 5.7 2.4e-09 37.7 5.2 3.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 GAP86441.1 - 1.8e-06 27.9 0.0 3.2e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 GAP86441.1 - 2.2e-06 28.2 0.6 0.56 10.9 0.0 3.7 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 GAP86441.1 - 0.057 14.0 0.1 25 5.5 0.0 3.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DNA_ligase_A_M PF01068.21 GAP86442.1 - 1.9e-58 197.5 0.7 6.4e-46 156.6 0.2 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAP86442.1 - 1.8e-45 155.4 0.0 1.8e-45 155.4 0.0 2.2 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 GAP86442.1 - 4.8e-29 100.9 0.0 2.5e-28 98.6 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 GAP86442.1 - 5.3e-05 23.6 0.3 9.2e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 RNA ligase PI3K_1B_p101 PF10486.9 GAP86442.1 - 3 5.5 9.4 4.3 5.0 9.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4778 PF16008.5 GAP86442.1 - 6.5 6.7 9.5 16 5.5 9.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) LRR_1 PF00560.33 GAP86444.1 - 0.16 12.6 3.0 71 4.6 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat Pkinase PF00069.25 GAP86446.1 - 9.3e-67 225.2 0.0 1.5e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86446.1 - 1.5e-48 165.4 0.0 2.5e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 GAP86446.1 - 8.9e-27 93.4 0.0 1.7e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 GAP86446.1 - 1.2e-16 60.6 0.3 3.5e-16 59.1 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAP86446.1 - 1.9e-16 60.3 0.1 3.7e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 GAP86446.1 - 2.1e-13 50.7 0.0 3.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 GAP86446.1 - 4.1e-07 29.6 0.0 0.00016 21.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.16 GAP86446.1 - 0.0025 17.7 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Pkinase_fungal PF17667.1 GAP86446.1 - 0.013 14.3 0.1 0.03 13.1 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase SAM_4 PF18017.1 GAP86446.1 - 0.026 14.5 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MRP-L51 PF10244.9 GAP86446.1 - 0.06 13.6 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit SAM_Ste50p PF09235.10 GAP86446.1 - 0.21 11.8 0.5 0.46 10.7 0.5 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif FA_hydroxylase PF04116.13 GAP86449.1 - 2.5e-24 86.1 13.6 1.1e-23 84.1 9.3 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily DUF3606 PF12244.8 GAP86449.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) TCTP PF00838.17 GAP86450.1 - 7.7e-66 221.5 1.3 8.6e-66 221.4 1.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Aminopep PF10023.9 GAP86450.1 - 0.096 12.0 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Putative aminopeptidase AIM3 PF17096.5 GAP86451.1 - 0.018 16.0 0.3 0.018 16.0 0.3 3.8 4 1 1 5 5 5 0 Altered inheritance of mitochondria protein 3 Mis12 PF05859.12 GAP86452.1 - 2.9e-46 156.9 0.0 4.1e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Mis12 protein PPR_2 PF13041.6 GAP86453.1 - 1.2e-24 86.2 0.1 2.5e-09 37.2 0.0 7.8 6 2 2 8 8 8 3 PPR repeat family PPR_long PF17177.4 GAP86453.1 - 1.3e-11 44.2 0.2 1.8e-05 24.3 0.7 3.4 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 GAP86453.1 - 2e-09 37.0 0.1 0.34 11.3 0.0 6.2 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 GAP86453.1 - 2.3e-09 37.2 0.2 0.00078 19.5 0.0 5.1 4 2 1 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 GAP86453.1 - 3.3e-07 29.9 0.0 0.11 12.2 0.0 4.7 4 0 0 4 4 4 2 PPR repeat MRP-S27 PF10037.9 GAP86453.1 - 0.0026 16.7 0.0 0.61 8.9 0.0 2.5 3 0 0 3 3 3 2 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 GAP86453.1 - 0.091 13.6 1.5 20 6.3 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4057 PF13266.6 GAP86453.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) His_Phos_2 PF00328.22 GAP86454.1 - 7e-15 55.3 0.0 3.1e-12 46.6 0.0 2.4 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.22 GAP86455.1 - 1.3e-36 124.2 0.1 1.2e-11 44.3 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAP86455.1 - 1.8e-14 53.4 0.0 0.042 13.7 0.0 4.4 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM_7 PF16367.5 GAP86455.1 - 2.1e-06 27.7 0.0 0.012 15.7 0.0 4.0 4 0 0 4 4 4 2 RNA recognition motif RRM PF10378.9 GAP86455.1 - 7.7e-06 25.5 11.6 7.7e-06 25.5 11.6 3.3 2 1 0 2 2 2 1 Putative RRM domain DUF4523 PF15023.6 GAP86455.1 - 6.2e-05 22.9 0.0 0.045 13.6 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 GAP86455.1 - 0.0036 17.3 0.1 0.18 11.9 0.2 3.0 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 GAP86455.1 - 0.021 14.8 0.0 6.3 6.9 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 GAP86455.1 - 0.083 12.9 0.7 0.42 10.7 0.0 2.5 4 0 0 4 4 4 0 RNA binding domain Arginase PF00491.21 GAP86456.1 - 4e-91 305.4 0.0 5.3e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 GAP86456.1 - 0.032 14.5 0.1 0.059 13.6 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain Ras PF00071.22 GAP86457.1 - 4.3e-53 179.2 0.0 5.1e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP86457.1 - 7e-19 68.2 0.0 9.7e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP86457.1 - 1.6e-06 27.7 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PET117 PF15786.5 GAP86457.1 - 0.062 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial GPS2_interact PF15784.5 GAP86458.1 - 0.035 14.6 2.4 0.085 13.3 0.4 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Pinin_SDK_N PF04697.13 GAP86458.1 - 0.39 11.4 5.2 0.072 13.7 1.1 1.8 2 0 0 2 2 2 0 pinin/SDK conserved region PI3_PI4_kinase PF00454.27 GAP86459.1 - 2.7e-50 171.5 0.0 6.2e-50 170.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 GAP86459.1 - 5.4e-39 133.7 0.0 2.2e-38 131.8 0.0 2.2 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 GAP86459.1 - 1.3e-11 44.1 0.1 4.8e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 GAP86459.1 - 2.4e-11 43.4 3.1 5.3e-11 42.3 3.1 1.5 1 0 0 1 1 1 1 FAT domain Nup192 PF11894.8 GAP86460.1 - 0 1327.9 0.4 0 1327.7 0.4 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 AA_permease PF00324.21 GAP86461.1 - 3.9e-126 421.4 39.6 4.8e-126 421.2 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP86461.1 - 1.3e-39 136.3 42.7 1.6e-39 136.0 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease AAA PF00004.29 GAP86462.1 - 6.5e-52 175.4 0.0 2.2e-42 144.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP86462.1 - 1.1e-08 35.7 0.1 0.0015 18.9 0.2 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 GAP86462.1 - 1.2e-07 31.4 0.0 3.8e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 GAP86462.1 - 8.9e-06 25.6 0.0 9e-05 22.3 0.0 2.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_2 PF07724.14 GAP86462.1 - 2.4e-05 24.5 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 GAP86462.1 - 0.00011 22.2 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAP86462.1 - 0.0012 19.1 0.3 0.077 13.3 0.1 3.3 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.14 GAP86462.1 - 0.0015 18.6 0.0 0.0068 16.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAP86462.1 - 0.0021 18.6 0.7 0.018 15.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAP86462.1 - 0.012 15.9 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.13 GAP86462.1 - 0.014 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 GAP86462.1 - 0.022 14.9 1.7 0.028 14.6 0.0 2.2 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 GAP86462.1 - 0.026 14.3 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 GAP86462.1 - 0.072 12.6 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAP86462.1 - 0.077 12.4 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 GAP86462.1 - 0.09 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 GAP86462.1 - 0.11 12.2 0.0 4.8 6.9 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Torsin PF06309.11 GAP86462.1 - 0.11 12.5 0.1 2.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_28 PF13521.6 GAP86462.1 - 0.2 11.9 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 GAP86462.1 - 0.92 9.2 0.0 0.92 9.2 0.0 3.1 3 1 1 4 4 3 0 AAA domain BLM10_N PF16547.5 GAP86463.1 - 0.088 13.1 0.2 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Dus PF01207.17 GAP86465.1 - 2.1e-59 201.1 0.0 3.3e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 GAP86465.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase API5 PF05918.11 GAP86465.1 - 0.22 10.3 0.6 0.41 9.4 0.6 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Plasmodium_Vir PF05795.11 GAP86465.1 - 1.1 8.6 2.5 1.6 8.1 2.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAD_binding_3 PF01494.19 GAP86467.1 - 2.9e-18 66.3 0.1 6.4e-18 65.1 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP86467.1 - 3e-10 39.8 2.0 1.4e-05 24.5 0.5 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAP86467.1 - 3.7e-07 29.8 0.3 0.012 15.0 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 GAP86467.1 - 7e-07 28.6 0.1 1e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAP86467.1 - 1e-06 28.9 0.6 2.6e-06 27.5 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP86467.1 - 6.5e-06 26.0 5.8 0.0015 18.2 1.4 3.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP86467.1 - 1.8e-05 24.0 1.8 3.8e-05 23.0 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAP86467.1 - 2.9e-05 24.6 2.2 0.014 15.9 1.4 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP86467.1 - 0.00015 21.1 0.2 0.026 13.8 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAP86467.1 - 0.00052 19.0 1.6 0.18 10.6 0.2 2.2 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 GAP86467.1 - 0.00062 18.6 1.9 0.0048 15.7 0.9 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 GAP86467.1 - 0.00063 18.9 0.7 0.00063 18.9 0.7 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAP86467.1 - 0.003 17.0 0.4 0.0054 16.1 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAP86467.1 - 0.0056 16.0 1.2 0.017 14.4 0.5 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAP86467.1 - 0.077 12.2 0.2 0.13 11.4 0.2 1.4 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 GAP86467.1 - 0.088 12.7 0.1 0.24 11.2 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MA3 PF02847.17 GAP86468.1 - 2.2e-21 76.0 0.0 5.1e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 GAP86468.1 - 2.5e-14 53.4 2.2 6.2e-14 52.1 0.1 2.3 2 1 0 2 2 2 1 MIF4G domain RRN3 PF05327.11 GAP86468.1 - 0.073 11.6 5.9 0.13 10.8 5.9 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF5523 PF17661.1 GAP86468.1 - 7.1 6.2 10.8 1.5 8.5 6.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Nop14 PF04147.12 GAP86468.1 - 8.2 4.5 13.5 0.26 9.5 6.7 1.9 2 0 0 2 2 2 0 Nop14-like family DIOX_N PF14226.6 GAP86469.1 - 5.9e-17 62.5 0.0 1.1e-16 61.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP86469.1 - 6.2e-08 33.1 0.0 1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MAGUK_N_PEST PF10608.9 GAP86469.1 - 0.025 15.0 0.0 0.067 13.6 0.0 1.7 1 1 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK AA_permease_2 PF13520.6 GAP86471.1 - 3.1e-53 181.2 47.2 3.7e-53 180.9 47.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP86471.1 - 8.1e-27 93.9 39.8 1.2e-26 93.4 39.8 1.2 1 0 0 1 1 1 1 Amino acid permease IncF PF17626.2 GAP86471.1 - 9.3 6.7 7.8 0.97 9.8 1.0 2.8 3 0 0 3 3 3 0 Inclusion membrane protein F Pyr_redox_2 PF07992.14 GAP86472.1 - 7.6e-11 41.8 0.0 2.8e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP86472.1 - 3.8e-06 25.9 0.0 0.0025 16.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 GAP86472.1 - 0.0013 17.9 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAP86472.1 - 0.0022 17.3 0.0 0.093 12.0 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP86472.1 - 0.023 14.9 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAP86472.1 - 0.033 13.4 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 GAP86472.1 - 0.036 14.1 0.0 6.2 6.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAP86472.1 - 0.04 13.1 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 GAP86472.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAP86472.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_23 PF13489.6 GAP86473.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAP86474.1 - 1.2e-12 48.4 0.0 3.2e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP86474.1 - 6.8e-12 45.9 0.0 3.5e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP86474.1 - 3.1e-07 30.0 0.0 5.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 GAP86474.1 - 3.6e-05 24.4 0.0 9.9e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP86474.1 - 0.00019 21.3 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.11 GAP86474.1 - 0.029 13.9 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Peptidase_M19 PF01244.21 GAP86475.1 - 6.5e-107 357.4 0.0 7.4e-107 357.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DPM2 PF07297.12 GAP86477.1 - 1.2e-30 105.6 1.9 1.3e-30 105.5 1.9 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 GAP86477.1 - 9.7e-05 22.3 1.4 0.00011 22.1 1.4 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 GAP86477.1 - 0.0007 19.6 0.4 0.0007 19.6 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) COX14 PF14880.6 GAP86477.1 - 0.007 16.2 3.7 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome oxidase c assembly LapA_dom PF06305.11 GAP86477.1 - 0.084 12.7 0.2 0.084 12.7 0.2 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ING PF12998.7 GAP86480.1 - 6.2e-06 26.7 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding MttA_Hcf106 PF02416.16 GAP86480.1 - 0.085 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 mttA/Hcf106 family LCD1 PF09798.9 GAP86480.1 - 0.09 11.3 1.4 0.12 10.9 1.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Filaggrin PF03516.13 GAP86480.1 - 6.4 7.6 14.2 2.8 8.7 8.6 2.8 2 0 0 2 2 2 0 Filaggrin Bactofilin PF04519.13 GAP86481.1 - 8.3e-05 22.8 0.6 0.0019 18.4 0.5 2.6 1 1 1 2 2 2 1 Polymer-forming cytoskeletal UBA PF00627.31 GAP86481.1 - 0.053 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain zf-C2H2 PF00096.26 GAP86483.1 - 0.013 15.9 3.5 0.045 14.2 3.5 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1970 PF09301.10 GAP86483.1 - 0.34 11.2 2.7 0.74 10.1 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1970) Sec1 PF00995.23 GAP86484.1 - 1.8e-133 446.8 0.0 2.1e-133 446.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MMM1 PF10296.9 GAP86485.1 - 1.4e-121 405.6 0.4 6.6e-118 393.6 0.0 3.0 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 CPBP PF02517.16 GAP86486.1 - 2.8e-13 50.0 12.6 2.8e-13 50.0 12.6 2.9 2 1 1 3 3 3 1 CPBP intramembrane metalloprotease DUF1635 PF07795.11 GAP86486.1 - 0.43 10.4 0.6 0.86 9.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) MBOAT PF03062.19 GAP86488.1 - 1.8e-54 185.4 6.0 3.2e-54 184.6 6.0 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.21 GAP86488.1 - 0.01 15.6 3.8 0.01 15.6 3.8 2.2 2 1 0 2 2 2 0 PAP2 superfamily DPM3 PF08285.11 GAP86488.1 - 0.057 13.6 3.9 0.068 13.4 0.2 2.9 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MraZ PF02381.18 GAP86488.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like DER1 PF04511.15 GAP86490.1 - 3e-50 170.8 6.5 3.4e-50 170.6 6.5 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.14 GAP86491.1 - 5e-46 156.8 0.8 5.7e-46 156.5 0.8 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 GAP86491.1 - 3.4e-09 36.3 0.0 6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 GAP86491.1 - 5.1e-06 26.4 0.0 7.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Meis_PKNOX_N PF16493.5 GAP86491.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.6 1 1 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 Cupin_1 PF00190.22 GAP86491.1 - 0.16 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Cupin adh_short PF00106.25 GAP86492.1 - 2.8e-27 95.5 0.0 3.8e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP86492.1 - 1.7e-20 73.6 0.0 2.4e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP86492.1 - 8.4e-08 32.3 0.0 1.7e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP86492.1 - 4.4e-05 23.1 0.0 0.00011 21.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAP86492.1 - 0.068 12.3 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 GAP86492.1 - 0.22 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family EamA PF00892.20 GAP86493.1 - 0.00098 19.3 10.3 0.00098 19.3 10.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family Histone PF00125.24 GAP86494.1 - 8.4e-41 139.4 0.0 9.7e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 GAP86494.1 - 0.00039 20.5 0.0 0.00054 20.1 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 GAP86494.1 - 0.00068 20.0 0.1 0.00099 19.4 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 GAP86494.1 - 0.012 15.9 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAP86494.1 - 0.048 13.7 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit FUN14 PF04930.15 GAP86495.1 - 0.063 13.7 2.7 0.063 13.7 2.7 1.8 2 0 0 2 2 2 0 FUN14 family Creatinase_N_2 PF16189.5 GAP86496.1 - 4.6e-56 189.4 0.7 7.9e-55 185.4 0.1 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 GAP86496.1 - 5.8e-44 150.3 0.0 8.5e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 GAP86496.1 - 4.6e-24 85.6 0.0 2.8e-20 73.3 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 GAP86496.1 - 1.8e-23 82.4 0.2 5.3e-23 80.9 0.2 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Importin_rep_3 PF18806.1 GAP86497.1 - 0.0009 19.2 0.0 0.0027 17.7 0.0 1.8 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep PF18773.1 GAP86497.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Importin 13 repeat MMS19_C PF12460.8 GAP86497.1 - 0.19 10.8 1.4 2.1 7.4 0.1 2.7 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Ribosomal_L32e PF01655.18 GAP86499.1 - 5.7e-50 168.3 0.9 6.7e-50 168.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 DnaJ_C PF01556.18 GAP86500.1 - 4.4e-35 120.9 0.1 6.6e-35 120.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 GAP86500.1 - 1.5e-24 85.9 1.7 2.4e-24 85.2 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 GAP86500.1 - 7.6e-14 51.8 17.6 1.3e-13 51.0 17.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 GAP86500.1 - 0.0057 16.6 12.4 0.078 13.0 1.9 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Forkhead_N PF08430.12 GAP86500.1 - 0.17 12.5 5.4 0.3 11.7 5.4 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region RSD-2 PF07547.13 GAP86500.1 - 0.18 12.3 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 RSD-2 N-terminal domain DUF1356 PF07092.12 GAP86500.1 - 0.22 10.8 2.9 1.2 8.3 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1356) HypA PF01155.19 GAP86500.1 - 0.28 11.2 6.4 5.2 7.1 0.5 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Keratin_2_head PF16208.5 GAP86500.1 - 0.6 10.2 14.4 1.3 9.1 14.4 1.5 1 0 0 1 1 1 0 Keratin type II head zf-RING_10 PF16685.5 GAP86500.1 - 0.75 10.0 6.3 5.8 7.1 0.7 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 tRNA-synt_1c PF00749.21 GAP86501.1 - 1.5e-94 316.5 0.0 2e-94 316.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain JAB PF01398.21 GAP86502.1 - 1.7e-31 108.6 0.5 4.6e-31 107.3 0.2 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 GAP86502.1 - 5.3e-20 72.1 0.3 1e-19 71.2 0.3 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 GAP86502.1 - 6e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 GAP86502.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) Ribosomal_S10 PF00338.22 GAP86503.1 - 1.3e-25 89.4 0.0 2.1e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FAM75 PF14650.6 GAP86503.1 - 0.078 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 FAM75 family tRNA-synt_1b PF00579.25 GAP86504.1 - 1.9e-68 230.9 0.0 2.6e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pyr_redox_2 PF07992.14 GAP86505.1 - 1.4e-35 122.9 0.0 4.4e-34 118.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP86505.1 - 3.8e-11 43.4 0.0 9.1e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP86505.1 - 0.094 11.9 0.0 2.3 7.4 0.1 2.3 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAP86506.1 - 3.1e-75 253.6 0.2 4e-75 253.2 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAP86506.1 - 3.9e-39 134.4 0.0 7.5e-39 133.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_oxidored PF12831.7 GAP86506.1 - 0.0004 19.9 0.2 0.0005 19.5 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAP86506.1 - 0.00057 19.2 0.1 0.00088 18.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 GAP86506.1 - 0.00061 19.0 0.2 0.0012 18.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAP86506.1 - 0.0042 17.3 0.3 0.013 15.7 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAP86506.1 - 0.0079 15.5 0.2 0.013 14.8 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP86506.1 - 0.0093 15.6 3.4 0.017 14.8 3.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP86506.1 - 0.04 13.2 0.5 0.098 11.9 0.5 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP86506.1 - 0.085 11.9 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 GAP86506.1 - 0.14 10.8 0.1 0.23 10.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein AAA_5 PF07728.14 GAP86507.1 - 7.3e-124 408.3 0.2 1.3e-21 77.0 0.0 10.0 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 GAP86507.1 - 1.1e-52 176.6 4.1 1.7e-22 79.6 0.0 6.0 6 0 0 6 6 5 3 Midasin AAA lid domain AAA PF00004.29 GAP86507.1 - 5.3e-33 114.3 0.0 0.00013 22.4 0.0 7.0 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 GAP86507.1 - 6.9e-32 110.1 0.0 6.1e-10 39.1 0.0 7.6 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 GAP86507.1 - 2.5e-30 105.3 0.2 1.5e-05 24.6 0.0 6.9 7 0 0 7 7 7 5 P-loop containing dynein motor region AAA_lid_5 PF17865.1 GAP86507.1 - 5.8e-30 103.5 0.1 9.6e-29 99.6 0.0 2.9 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_16 PF13191.6 GAP86507.1 - 3.2e-28 99.2 22.1 0.00012 22.5 0.1 9.4 8 2 0 8 8 7 6 AAA ATPase domain Dynein_heavy PF03028.15 GAP86507.1 - 3.3e-27 94.9 0.0 0.00067 19.7 0.0 8.9 9 1 0 9 9 7 5 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 GAP86507.1 - 3e-23 82.3 0.0 0.0025 16.8 0.0 9.1 9 1 0 9 9 9 5 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 GAP86507.1 - 6.5e-23 81.5 0.1 0.0076 16.5 0.0 7.6 6 0 0 6 6 6 4 AAA domain AAA_18 PF13238.6 GAP86507.1 - 2.7e-22 79.7 0.1 0.001 19.6 0.0 7.6 7 0 0 7 7 6 3 AAA domain AAA_33 PF13671.6 GAP86507.1 - 4.1e-21 75.6 0.1 0.0023 18.1 0.0 6.9 6 0 0 6 6 6 4 AAA domain AAA_14 PF13173.6 GAP86507.1 - 7.9e-19 68.0 0.0 0.0061 16.6 0.0 8.1 7 1 0 7 7 6 3 AAA domain TsaE PF02367.17 GAP86507.1 - 1.3e-18 67.2 2.1 0.0073 16.3 0.1 6.5 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 GAP86507.1 - 1.3e-17 64.0 0.0 0.016 14.9 0.0 6.5 6 0 0 6 6 6 3 Sigma-54 interaction domain RNA_helicase PF00910.22 GAP86507.1 - 4.9e-16 59.0 0.9 0.16 12.3 0.0 6.8 6 0 0 6 6 6 3 RNA helicase Sigma54_activ_2 PF14532.6 GAP86507.1 - 2.3e-15 57.0 0.5 0.00015 21.9 0.0 6.6 6 0 0 6 6 5 2 Sigma-54 interaction domain NACHT PF05729.12 GAP86507.1 - 3.2e-15 56.4 4.6 0.051 13.5 0.0 6.8 6 0 0 6 6 6 4 NACHT domain RuvB_N PF05496.12 GAP86507.1 - 3.8e-14 52.7 4.3 0.00031 20.5 0.0 6.8 6 1 1 7 7 7 2 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 GAP86507.1 - 6.3e-14 52.7 9.0 0.01 16.4 0.0 7.2 7 0 0 7 7 6 3 ABC transporter AAA_30 PF13604.6 GAP86507.1 - 1.2e-13 51.2 0.0 0.022 14.5 0.0 7.2 6 1 0 6 6 6 2 AAA domain Zeta_toxin PF06414.12 GAP86507.1 - 1.4e-13 50.6 1.7 0.021 14.1 0.0 6.6 6 0 0 6 6 6 2 Zeta toxin RsgA_GTPase PF03193.16 GAP86507.1 - 1.5e-13 51.0 2.5 0.17 11.8 0.0 6.5 6 0 0 6 6 6 3 RsgA GTPase AAA_28 PF13521.6 GAP86507.1 - 5.6e-13 49.5 3.4 0.37 11.0 0.1 7.3 6 0 0 6 6 6 2 AAA domain Mg_chelatase PF01078.21 GAP86507.1 - 6.7e-13 48.5 2.8 2.4 7.5 0.0 8.6 8 0 0 8 8 8 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 GAP86507.1 - 8.7e-13 48.6 3.1 0.082 12.8 0.0 6.5 6 0 0 6 6 6 2 Rad17 P-loop domain T2SSE PF00437.20 GAP86507.1 - 1.4e-12 47.3 1.2 0.031 13.4 0.0 6.2 6 0 0 6 6 6 3 Type II/IV secretion system protein AAA_25 PF13481.6 GAP86507.1 - 9.1e-11 41.7 1.5 1.4 8.5 0.0 5.6 5 0 0 5 5 5 2 AAA domain Viral_helicase1 PF01443.18 GAP86507.1 - 7.4e-10 39.0 0.0 0.066 12.9 0.0 6.0 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 GAP86507.1 - 3.2e-09 36.8 0.4 3 7.5 0.0 6.1 6 0 0 6 6 5 0 IstB-like ATP binding protein TniB PF05621.11 GAP86507.1 - 5.3e-09 35.7 0.3 2.9 7.2 0.0 7.2 8 0 0 8 8 7 0 Bacterial TniB protein AAA_19 PF13245.6 GAP86507.1 - 6.7e-09 36.2 4.9 0.92 9.8 0.0 6.1 6 0 0 6 6 5 1 AAA domain ATPase_2 PF01637.18 GAP86507.1 - 1.2e-08 35.1 0.0 0.041 13.8 0.0 6.1 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea SRP54 PF00448.22 GAP86507.1 - 2.3e-08 33.9 1.4 1 9.0 0.0 5.5 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 GAP86507.1 - 5e-08 32.8 2.0 0.07 12.9 0.0 5.7 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 GAP86507.1 - 6.1e-08 32.3 0.2 7.6 6.4 0.0 6.3 6 0 0 6 6 6 0 P-loop containing region of AAA domain AAA_17 PF13207.6 GAP86507.1 - 1.7e-07 31.8 4.0 1.5 9.2 0.0 6.0 5 0 0 5 5 5 2 AAA domain MMR_HSR1 PF01926.23 GAP86507.1 - 2.8e-07 30.6 0.5 6.1 7.0 0.0 6.7 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_24 PF13479.6 GAP86507.1 - 7.3e-07 29.1 0.1 3.4 7.3 0.0 6.4 6 0 0 6 6 6 0 AAA domain dNK PF01712.19 GAP86507.1 - 1.5e-06 28.2 2.6 13 5.6 0.0 5.9 6 0 0 6 6 5 0 Deoxynucleoside kinase DUF815 PF05673.13 GAP86507.1 - 3.1e-06 26.5 2.8 4.3 6.4 0.0 5.7 6 0 0 6 6 6 0 Protein of unknown function (DUF815) Roc PF08477.13 GAP86507.1 - 4.2e-06 27.0 1.2 9.2 6.5 0.0 6.2 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 GAP86507.1 - 7.1e-06 25.7 5.8 8.2 6.0 0.3 6.1 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 GAP86507.1 - 1.4e-05 25.1 7.8 1.7 8.5 0.1 5.9 6 0 0 6 6 5 2 NTPase NB-ARC PF00931.22 GAP86507.1 - 1.5e-05 24.3 4.5 2.2 7.4 0.0 5.9 6 0 0 6 6 5 1 NB-ARC domain MCM PF00493.23 GAP86507.1 - 9.4e-05 21.6 0.3 20 4.2 0.0 6.3 8 0 0 8 8 7 0 MCM P-loop domain TIP49 PF06068.13 GAP86507.1 - 0.00013 21.3 0.2 15 4.6 0.0 4.7 5 0 0 5 5 4 0 TIP49 P-loop domain ResIII PF04851.15 GAP86507.1 - 0.00015 21.8 0.1 8.4 6.4 0.0 5.4 6 0 0 6 6 5 0 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.17 GAP86507.1 - 0.00035 20.3 1.2 7.5 6.2 0.0 5.6 6 0 0 6 6 5 0 Thymidylate kinase KAP_NTPase PF07693.14 GAP86507.1 - 0.0004 19.7 0.0 7.3 5.7 0.0 4.9 5 0 0 5 5 5 0 KAP family P-loop domain SRPRB PF09439.10 GAP86507.1 - 0.0007 19.1 0.5 52 3.2 0.0 5.6 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit AAA_9 PF12781.7 GAP86507.1 - 0.0016 17.6 0.0 0.31 10.1 0.0 4.4 5 0 0 5 5 4 1 ATP-binding dynein motor region Cytidylate_kin PF02224.18 GAP86507.1 - 0.0028 17.4 0.9 59 3.3 0.1 5.1 5 0 0 5 5 5 0 Cytidylate kinase SKI PF01202.22 GAP86507.1 - 0.0029 17.7 0.7 20 5.3 0.0 4.3 4 0 0 4 4 3 0 Shikimate kinase KTI12 PF08433.10 GAP86507.1 - 0.0031 17.0 0.1 0.29 10.5 0.0 4.0 5 0 0 5 5 3 1 Chromatin associated protein KTI12 DUF4208 PF13907.6 GAP86507.1 - 0.0035 17.8 0.1 4.4 7.8 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) ATP_bind_1 PF03029.17 GAP86507.1 - 0.0054 16.5 7.5 10 5.8 0.1 5.7 7 0 0 7 7 4 0 Conserved hypothetical ATP binding protein CbiA PF01656.23 GAP86507.1 - 0.0065 16.5 0.1 35 4.5 0.0 5.1 5 0 0 5 5 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 GAP86507.1 - 0.0068 15.4 1.8 10 5.0 0.1 3.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 GAP86507.1 - 0.0088 15.4 0.5 11 5.2 0.0 4.6 5 0 0 5 5 4 0 KaiC GAF_2 PF13185.6 GAP86507.1 - 0.009 16.3 0.0 0.12 12.7 0.0 3.0 3 0 0 3 3 1 1 GAF domain DEAD PF00270.29 GAP86507.1 - 0.011 15.6 0.1 8.9 6.0 0.0 4.3 4 0 0 4 4 4 0 DEAD/DEAH box helicase CPT PF07931.12 GAP86507.1 - 0.011 15.5 2.1 62 3.4 0.0 6.1 7 1 0 7 7 3 0 Chloramphenicol phosphotransferase-like protein DAP3 PF10236.9 GAP86507.1 - 0.015 14.5 5.7 3.9 6.5 0.1 5.0 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 VWA_2 PF13519.6 GAP86507.1 - 0.017 15.7 2.6 3.1 8.5 0.0 3.5 3 0 0 3 3 2 0 von Willebrand factor type A domain PRK PF00485.18 GAP86507.1 - 0.033 13.9 0.3 35 4.1 0.0 4.3 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 GAP86507.1 - 0.047 13.0 0.3 23 4.1 0.0 4.2 5 0 0 5 5 5 0 Septin TrwB_AAD_bind PF10412.9 GAP86507.1 - 0.081 11.8 0.7 34 3.2 0.0 4.1 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain tRNA_lig_kinase PF08303.11 GAP86507.1 - 0.15 12.2 2.4 1.6 8.8 0.0 3.9 4 0 0 4 4 3 0 tRNA ligase kinase domain PhoH PF02562.16 GAP86507.1 - 0.17 11.3 0.2 11 5.4 0.0 3.5 4 0 0 4 4 4 0 PhoH-like protein APS_kinase PF01583.20 GAP86507.1 - 0.19 11.6 0.3 17 5.3 0.0 3.7 4 0 0 4 4 3 0 Adenylylsulphate kinase FeoB_N PF02421.18 GAP86507.1 - 0.3 10.6 1.1 46 3.5 0.0 4.3 5 0 0 5 5 4 0 Ferrous iron transport protein B Hpr_kinase_C PF07475.12 GAP86507.1 - 1.2 8.6 3.2 1.3 8.5 0.1 2.7 4 0 0 4 4 1 0 HPr Serine kinase C-terminal domain MobB PF03205.14 GAP86507.1 - 4.8 7.1 6.1 66 3.4 0.1 4.8 6 0 0 6 6 4 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_L12 PF00542.19 GAP86508.1 - 7.5e-21 74.3 7.2 4.7e-20 71.7 6.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 GAP86508.1 - 1.8e-14 53.2 2.8 2.3e-14 52.8 1.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 GAP86508.1 - 0.043 13.6 0.9 0.1 12.4 0.3 1.9 2 1 0 2 2 2 0 Stage VI sporulation protein F ApbA PF02558.16 GAP86509.1 - 8.5e-24 83.9 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 GAP86509.1 - 6.6e-23 81.3 0.0 1.1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 GAP86509.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Zip PF02535.22 GAP86510.1 - 1.5e-36 126.3 14.8 1.6e-27 96.6 9.4 2.9 1 1 1 2 2 2 2 ZIP Zinc transporter Hat1_N PF10394.9 GAP86511.1 - 6e-46 156.6 0.0 9.9e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 GAP86511.1 - 0.0034 17.6 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP86511.1 - 0.012 15.6 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 GAP86511.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Cas_Cas1 PF01867.16 GAP86511.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas1 P5CR_dimer PF14748.6 GAP86512.1 - 3.4e-33 114.0 3.1 6.1e-33 113.2 3.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAP86512.1 - 2.7e-10 40.7 0.9 1.6e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Thioredoxin_3 PF13192.6 GAP86512.1 - 0.062 13.4 0.2 0.21 11.7 0.2 1.9 1 0 0 1 1 1 0 Thioredoxin domain CTK3 PF12243.8 GAP86513.1 - 1.1e-51 174.0 0.8 1.6e-51 173.5 0.8 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 GAP86513.1 - 4.2e-17 62.1 1.7 4.2e-17 62.1 1.7 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus DUF3873 PF12989.7 GAP86513.1 - 0.072 13.5 0.1 0.98 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) WD40 PF00400.32 GAP86514.1 - 2.5e-37 126.2 26.0 1.6e-07 31.9 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 GAP86514.1 - 1.5e-12 47.2 1.5 3.1e-12 46.2 1.5 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 GAP86514.1 - 3.2e-11 43.4 3.6 0.15 12.4 0.0 6.1 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GAP86514.1 - 4.5e-07 29.6 2.5 9.2e-07 28.6 2.5 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 GAP86514.1 - 5e-06 25.4 8.2 0.75 8.4 0.1 6.0 1 1 6 7 7 7 2 Nucleoporin Nup120/160 WD40_like PF17005.5 GAP86514.1 - 0.00014 21.3 0.0 0.016 14.6 0.0 2.4 1 1 2 3 3 3 3 WD40-like domain PQQ_2 PF13360.6 GAP86514.1 - 0.002 17.7 2.8 0.0034 17.0 1.3 2.0 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 GAP86514.1 - 0.0023 18.4 1.2 6.1 7.5 0.0 4.5 4 0 0 4 4 4 1 PQQ-like domain BBS2_Mid PF14783.6 GAP86514.1 - 0.0087 16.1 0.0 3.8 7.6 0.0 3.4 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region EH_Signature PF15611.6 GAP86514.1 - 0.12 11.8 0.1 3.6 6.9 0.1 2.4 3 0 0 3 3 3 0 EH_Signature domain DUF2178 PF09946.9 GAP86514.1 - 0.25 11.5 0.0 0.63 10.2 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) TPR_6 PF13174.6 GAP86515.1 - 1.2 10.0 4.4 97 3.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.11 GAP86516.1 - 3.4e-14 53.3 0.0 3.4e-14 53.3 0.0 5.3 2 1 2 4 4 4 1 U3 snoRNA associated MFS_1 PF07690.16 GAP86517.1 - 4.6e-20 71.8 49.3 4.6e-20 71.8 49.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1180 PF06679.12 GAP86517.1 - 0.14 12.5 0.5 0.88 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) PH_10 PF15411.6 GAP86518.1 - 4.5e-30 104.4 0.3 7.8e-30 103.7 0.3 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 GAP86518.1 - 9.9e-15 55.2 0.0 1.5e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAP86518.1 - 1.2e-10 41.5 0.1 5.9e-10 39.3 0.1 2.1 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 GAP86518.1 - 0.0008 19.7 5.7 0.0014 18.9 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 GAP86518.1 - 0.002 17.7 2.8 0.002 17.7 2.8 1.6 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 GAP86518.1 - 0.017 15.1 5.8 0.029 14.3 5.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 GAP86518.1 - 0.023 15.0 2.9 0.05 13.9 2.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 GAP86518.1 - 0.088 12.6 4.2 0.21 11.4 4.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 GAP86518.1 - 0.1 12.5 4.8 0.19 11.6 4.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP86518.1 - 0.12 12.3 5.5 0.25 11.2 5.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 GAP86518.1 - 0.23 11.8 4.3 0.42 11.0 4.3 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 GAP86518.1 - 0.83 9.6 2.8 4.6 7.3 0.2 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 GAP86518.1 - 2.7 8.1 5.7 5.7 7.1 5.7 1.6 1 0 0 1 1 1 0 Zinc-finger FMO-like PF00743.19 GAP86519.1 - 3.1e-45 154.6 0.0 1.2e-22 80.1 0.0 3.2 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 GAP86519.1 - 4e-19 69.0 0.0 1.8e-13 50.4 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP86519.1 - 5.9e-15 55.3 0.0 3e-08 33.3 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP86519.1 - 1.1e-09 38.3 0.1 1.6e-08 34.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAP86519.1 - 3.9e-08 33.4 0.7 3.8e-05 23.7 0.1 3.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 GAP86519.1 - 1.2e-07 31.7 7.4 0.00022 20.9 2.0 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAP86519.1 - 5.1e-07 29.4 0.2 0.0023 17.3 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 GAP86519.1 - 6.2e-07 28.9 1.3 0.00018 20.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 GAP86519.1 - 8.1e-06 26.3 0.6 0.0016 19.0 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GAP86519.1 - 0.00015 21.8 0.1 0.032 14.3 0.1 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 GAP86519.1 - 0.00093 18.5 1.0 0.005 16.1 0.3 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 GAP86519.1 - 0.0014 17.8 0.3 0.0077 15.4 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GAP86519.1 - 0.0018 17.7 0.6 0.0029 17.0 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAP86519.1 - 0.0028 16.4 0.6 0.0028 16.4 0.6 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 GAP86519.1 - 0.01 15.0 1.6 0.019 14.1 0.3 2.1 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAP86519.1 - 0.022 14.1 0.9 0.12 11.7 0.2 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 GAP86519.1 - 0.022 14.0 0.5 0.045 13.0 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 GAP86519.1 - 0.052 13.4 0.5 0.099 12.5 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAP86519.1 - 0.069 13.3 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 GAP86519.1 - 0.095 13.2 0.2 4.6 7.7 0.0 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 GAP86519.1 - 0.15 11.4 0.3 0.91 8.9 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 GAP86519.1 - 0.26 10.9 1.1 1.5 8.5 0.9 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Cpn60_TCP1 PF00118.24 GAP86520.1 - 7.6e-151 503.1 10.0 8.6e-151 502.9 10.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 GAP86520.1 - 0.00076 19.1 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 EAL domain DUF2204 PF09970.9 GAP86520.1 - 0.002 17.8 0.2 0.62 9.7 0.0 3.0 3 0 0 3 3 3 2 Nucleotidyl transferase of unknown function (DUF2204) PrpR_N PF06506.11 GAP86520.1 - 0.026 14.1 0.1 0.087 12.4 0.1 1.9 1 0 0 1 1 1 0 Propionate catabolism activator HMG_box PF00505.19 GAP86521.1 - 1.5e-08 35.0 3.7 1.5e-08 35.0 3.7 2.4 2 1 1 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAP86521.1 - 3.4e-05 24.4 1.3 3.4e-05 24.4 1.3 2.5 2 1 1 3 3 3 1 HMG-box domain bZIP_1 PF00170.21 GAP86521.1 - 0.00042 20.4 1.4 0.00042 20.4 1.4 2.2 3 0 0 3 3 3 1 bZIP transcription factor MbeD_MobD PF04899.12 GAP86521.1 - 0.15 12.2 5.1 2.6 8.2 1.4 2.3 2 0 0 2 2 2 0 MbeD/MobD like Trypan_PARP PF05887.11 GAP86521.1 - 0.74 9.8 15.2 0.24 11.4 7.1 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF155 PF02582.14 GAP86522.1 - 2.3e-50 171.2 0.1 3.1e-50 170.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Sacchrp_dh_NADP PF03435.18 GAP86523.1 - 1.7e-14 54.2 0.1 3.7e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 GAP86523.1 - 8.3e-06 26.2 0.0 1.6e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PHD PF00628.29 GAP86524.1 - 2.5e-09 36.9 6.4 2.5e-09 36.9 6.4 2.9 2 1 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 GAP86524.1 - 4e-08 33.5 1.0 4e-08 33.5 1.0 4.3 3 1 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 GAP86524.1 - 1.6e-07 31.5 9.6 3.2e-07 30.5 0.6 3.0 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAP86524.1 - 4.4e-05 23.4 0.6 4.4e-05 23.4 0.6 3.7 4 1 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAP86524.1 - 4.5e-05 23.2 1.5 4.5e-05 23.2 1.5 4.0 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAP86524.1 - 5.4e-05 23.2 0.4 5.4e-05 23.2 0.4 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAP86524.1 - 5.6e-05 22.9 1.7 5.6e-05 22.9 1.7 3.8 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 GAP86524.1 - 0.00011 21.9 0.6 0.00011 21.9 0.6 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP86524.1 - 0.00031 20.5 0.7 0.00031 20.5 0.7 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAP86524.1 - 0.00048 19.7 1.3 0.00048 19.7 1.3 2.5 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Rtf2 PF04641.12 GAP86524.1 - 0.008 15.6 0.0 0.025 14.0 0.0 1.8 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_1 PF14446.6 GAP86524.1 - 0.009 15.9 3.9 0.009 15.9 3.9 3.6 3 1 1 4 4 4 1 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.6 GAP86524.1 - 0.013 15.5 0.8 0.013 15.5 0.8 4.9 3 2 1 4 4 3 0 RING-type zinc-finger PHD_2 PF13831.6 GAP86524.1 - 0.014 14.9 3.2 0.014 14.9 3.2 2.3 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 GAP86524.1 - 0.96 9.0 6.8 0.4 10.3 0.9 2.7 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain RINGv PF12906.7 GAP86524.1 - 1.2 9.3 8.4 0.36 11.0 1.9 2.7 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 GAP86524.1 - 1.4 9.2 8.4 0.72 10.1 0.5 2.7 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_9 PF13901.6 GAP86524.1 - 2.3 8.2 10.6 4.5 7.2 0.9 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon DUF1644 PF07800.12 GAP86524.1 - 7.6 6.6 9.5 11 6.1 3.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1644) DnaJ PF00226.31 GAP86525.1 - 2e-12 47.0 0.1 4.1e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain FlxA PF14282.6 GAP86525.1 - 0.014 15.4 0.9 0.78 9.8 0.0 2.7 2 0 0 2 2 2 0 FlxA-like protein RRXRR PF14239.6 GAP86525.1 - 8.4 6.2 13.9 1.2 9.0 0.4 2.4 2 1 0 2 2 2 0 RRXRR protein Pkinase PF00069.25 GAP86526.1 - 5e-62 209.7 0.0 6.1e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86526.1 - 2.7e-34 118.6 0.0 4.1e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP86526.1 - 1.3e-05 24.7 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAP86526.1 - 0.00051 18.9 0.0 0.00073 18.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 GAP86527.1 - 1.6e-131 438.9 0.0 2.1e-131 438.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 GAP86527.1 - 3.6e-07 29.8 0.0 6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAP86527.1 - 0.028 14.3 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 GAP86527.1 - 0.065 12.6 0.1 2 7.7 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 GAP86527.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DEAD PF00270.29 GAP86528.1 - 2.7e-39 134.7 0.4 2.6e-38 131.6 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP86528.1 - 1.4e-29 102.7 0.0 2.8e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP86528.1 - 0.00021 21.4 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAP86528.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase LSDAT_prok PF18171.1 GAP86528.1 - 0.08 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote BUD22 PF09073.10 GAP86529.1 - 0.46 9.8 13.6 0.61 9.4 13.6 1.2 1 0 0 1 1 1 0 BUD22 PBP1_TM PF14812.6 GAP86529.1 - 8.3 6.9 12.3 6.4 7.2 4.1 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GCV_T PF01571.21 GAP86531.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain GTP_EFTU PF00009.27 GAP86532.1 - 1.5e-56 191.1 0.0 2.1e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 GAP86532.1 - 1e-15 57.5 0.0 2.6e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAP86532.1 - 1.3e-09 38.3 0.0 3.1e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAP86532.1 - 1.8e-07 31.1 0.0 3.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 GAP86532.1 - 0.0016 18.2 0.1 0.064 13.0 0.0 3.1 3 1 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 GAP86532.1 - 0.049 13.7 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Paf67 PF10255.9 GAP86533.1 - 1.5e-156 521.5 0.2 1.8e-156 521.2 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Usp PF00582.26 GAP86535.1 - 4.1e-16 59.8 0.2 1.4e-15 58.0 0.0 2.0 2 0 0 2 2 2 1 Universal stress protein family Amidohydro_2 PF04909.14 GAP86536.1 - 2.1e-26 93.4 0.2 4.3e-26 92.4 0.2 1.6 1 1 0 1 1 1 1 Amidohydrolase DIOX_N PF14226.6 GAP86537.1 - 1.8e-24 86.8 0.0 3.1e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP86537.1 - 5.4e-18 65.3 0.0 8.7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GBP_repeat PF02526.14 GAP86537.1 - 0.22 11.3 2.1 6.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Glycophorin-binding protein PGAP1 PF07819.13 GAP86538.1 - 0.0022 17.7 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAP86538.1 - 0.024 15.2 6.2 0.018 15.6 4.6 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP86538.1 - 0.03 13.6 0.2 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PTPLA PF04387.14 GAP86539.1 - 4.5e-54 182.6 9.1 6.1e-54 182.2 9.1 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Ribosomal_S14 PF00253.21 GAP86540.1 - 0.012 15.3 0.1 0.084 12.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e NBD94 PF16830.5 GAP86541.1 - 0.034 14.5 3.7 1.1 9.7 0.3 2.6 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH WD40 PF00400.32 GAP86543.1 - 8.7e-30 102.3 16.0 3.3e-06 27.7 0.0 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP86543.1 - 5.1e-10 39.5 0.2 0.0041 17.4 0.0 5.8 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 GAP86543.1 - 1.4e-08 34.5 0.2 1.4e-08 34.5 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAP86543.1 - 1.2e-06 28.3 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 GAP86543.1 - 0.00066 18.5 1.1 0.22 10.1 0.0 3.4 1 1 0 4 4 4 1 Nucleoporin Nup120/160 FlaG PF03646.15 GAP86543.1 - 0.029 14.5 0.0 0.91 9.7 0.0 2.9 3 0 0 3 3 3 0 FlaG protein PQQ PF01011.21 GAP86543.1 - 0.05 13.5 0.0 2.8 8.0 0.0 3.3 4 0 0 4 4 4 0 PQQ enzyme repeat Zn_clus PF00172.18 GAP86544.1 - 0.0001 22.3 14.1 0.00018 21.6 14.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhlB PF12300.8 GAP86544.1 - 1.5 8.9 11.7 0.14 12.3 2.0 3.0 3 0 0 3 3 3 0 ATP-dependent RNA helicase RhlB Zn_clus PF00172.18 GAP86546.1 - 9.7e-08 32.0 5.7 1.5e-07 31.4 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 GAP86547.1 - 0.0019 18.9 2.4 1.7 9.7 0.7 3.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAP86547.1 - 0.0043 17.4 1.9 0.33 11.5 0.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type ABC_trans_CmpB PF06541.11 GAP86548.1 - 0.0062 16.8 4.2 0.0062 16.8 4.2 1.9 1 1 1 2 2 2 1 Putative ABC-transporter type IV Herpes_UL69 PF05459.12 GAP86548.1 - 0.12 11.7 0.6 0.49 9.7 0.6 1.8 1 1 0 1 1 1 0 Herpesvirus transcriptional regulator family Ribosomal_L1 PF00687.21 GAP86549.1 - 4.4e-47 160.4 0.3 5.1e-47 160.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NUDIX PF00293.28 GAP86550.1 - 3.8e-17 62.6 0.0 1.3e-16 60.9 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.11 GAP86550.1 - 3.5e-12 46.9 0.0 9.8e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 GAP86550.1 - 0.00011 21.7 0.7 0.0002 20.9 0.7 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PQ-loop PF04193.14 GAP86551.1 - 1.2e-39 133.8 8.9 1.1e-19 69.9 1.5 2.5 2 0 0 2 2 2 2 PQ loop repeat MASE4 PF17158.4 GAP86551.1 - 0.21 10.8 2.8 6.3 6.0 0.0 2.4 2 0 0 2 2 2 0 Membrane-associated sensor, integral membrane domain Glyco_hydro_88 PF07470.13 GAP86552.1 - 7.3e-65 219.3 7.0 8.6e-65 219.1 7.0 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 RAMA PF18755.1 GAP86552.1 - 0.13 12.7 0.7 21 5.5 0.0 3.1 3 0 0 3 3 3 0 Restriction Enzyme Adenine Methylase Associated DUF4491 PF14898.6 GAP86553.1 - 7.7 7.0 14.5 16 6.0 6.5 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4491) FAD_binding_7 PF03441.14 GAP86554.1 - 7.5e-73 244.3 0.6 1.1e-72 243.8 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAP86554.1 - 1.7e-36 125.7 0.0 4.3e-36 124.4 0.0 1.7 1 0 0 1 1 1 1 DNA photolyase Inositol_P PF00459.25 GAP86554.1 - 2.4e-33 115.8 0.1 6.9e-33 114.3 0.1 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family DUF543 PF04418.12 GAP86555.1 - 2.8e-30 104.1 0.0 3.2e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.9 GAP86556.1 - 1.3e-55 188.5 0.2 1.9e-54 184.7 0.0 2.6 2 0 0 2 2 2 1 Urb2/Npa2 family NRDE-2 PF08424.10 GAP86557.1 - 8.5e-96 320.9 0.4 2.8e-95 319.2 0.5 1.8 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 GAP86557.1 - 0.00023 21.7 10.6 0.17 12.8 0.1 6.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAP86557.1 - 0.0021 18.5 3.3 1.6 9.3 0.1 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAP86557.1 - 0.1 13.0 0.1 0.7 10.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CAP_N PF01213.19 GAP86557.1 - 0.12 11.8 1.3 11 5.3 0.7 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Voltage_CLC PF00654.20 GAP86558.1 - 2.5e-89 300.0 21.5 2.5e-89 300.0 21.5 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel UCR_Fe-S_N PF10399.9 GAP86558.1 - 6.1 6.3 5.5 1.1 8.7 1.1 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF924 PF06041.11 GAP86560.1 - 5.4e-39 134.2 0.0 6.5e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) TPR_2 PF07719.17 GAP86561.1 - 1.9e-08 33.8 35.8 0.024 14.7 0.1 9.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAP86561.1 - 3.6e-08 33.0 12.7 0.02 15.1 0.1 7.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAP86561.1 - 2.5e-06 27.9 22.9 0.068 13.7 0.1 7.8 5 2 2 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP86561.1 - 8.2e-05 22.3 24.0 0.13 12.2 0.1 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP86561.1 - 9e-05 22.2 3.0 0.17 12.0 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAP86561.1 - 0.00024 21.7 37.6 0.024 15.3 6.8 7.9 7 1 2 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAP86561.1 - 0.00031 21.3 32.3 0.79 10.7 0.1 9.7 9 1 1 10 10 10 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 GAP86561.1 - 0.0033 17.9 1.5 2.4 8.6 0.2 3.3 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_17 PF13431.6 GAP86561.1 - 0.006 16.9 12.4 5.8 7.5 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP86561.1 - 0.027 15.1 12.9 0.17 12.6 0.0 5.0 4 1 0 4 4 3 0 Tetratricopeptide repeat DUF2989 PF11207.8 GAP86561.1 - 0.044 13.6 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) TPR_12 PF13424.6 GAP86561.1 - 0.077 13.3 25.9 1.2 9.5 6.8 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat PPTA PF01239.22 GAP86561.1 - 0.14 11.9 0.1 0.46 10.3 0.1 1.9 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat TPR_MalT PF17874.1 GAP86561.1 - 1.5 8.1 7.5 6.1 6.1 1.4 3.2 3 0 0 3 3 3 0 MalT-like TPR region TPR_20 PF14561.6 GAP86561.1 - 5.2 7.5 12.6 30 5.0 3.3 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat SAM_2 PF07647.17 GAP86562.1 - 2e-09 37.4 0.1 3.9e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAP86562.1 - 3.4e-05 24.2 0.1 6.4e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 GAP86562.1 - 0.067 13.3 0.2 0.19 11.9 0.1 1.7 2 0 0 2 2 2 0 IGR protein motif SAM_3 PF18016.1 GAP86562.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Mito_carr PF00153.27 GAP86563.1 - 2.8e-57 190.6 1.9 4.5e-20 71.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAP86563.1 - 0.026 13.7 0.5 0.11 11.7 0.0 2.2 2 1 1 3 3 3 0 Gammaproteobacterial serine protease Peptidase_C2 PF00648.21 GAP86564.1 - 2e-30 105.8 0.0 3.6e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 GAP86564.1 - 1.4e-09 38.4 0.0 0.00044 20.5 0.0 3.6 3 0 0 3 3 3 2 Calpain large subunit, domain III zf-C2H2 PF00096.26 GAP86565.1 - 3.7e-07 30.2 12.6 0.005 17.2 2.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP86565.1 - 0.0012 19.1 7.9 3 8.4 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP86565.1 - 0.024 15.5 11.1 0.11 13.4 1.7 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 GAP86565.1 - 0.31 11.4 6.8 0.31 11.4 1.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ADH_N PF08240.12 GAP86567.1 - 1.3e-27 95.9 0.4 2.1e-27 95.1 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP86567.1 - 4.6e-14 52.5 0.0 9.4e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAP86567.1 - 1.8e-05 24.3 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 GAP86567.1 - 0.0044 16.9 0.1 0.0094 15.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 GAP86567.1 - 0.072 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sen15 PF09631.10 GAP86568.1 - 1.2e-26 93.0 0.0 1.4e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein DUF2985 PF11204.8 GAP86569.1 - 6.8e-31 106.3 0.5 1.4e-30 105.3 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) AAA PF00004.29 GAP86570.1 - 8.2e-07 29.5 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAP86570.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAP86570.1 - 0.0013 19.2 0.0 0.0045 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP86570.1 - 0.0042 17.4 0.0 0.0085 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 GAP86570.1 - 0.047 13.3 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAP86570.1 - 0.062 13.8 0.0 0.25 11.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain MCM PF00493.23 GAP86570.1 - 0.092 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_33 PF13671.6 GAP86570.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Syntaxin_2 PF14523.6 GAP86571.1 - 2.5e-05 24.6 0.2 6.6e-05 23.2 0.2 1.7 1 0 0 1 1 1 1 Syntaxin-like protein DUF1664 PF07889.12 GAP86571.1 - 0.018 15.0 0.3 0.046 13.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CREPT PF16566.5 GAP86571.1 - 0.084 13.0 0.4 2 8.6 0.4 2.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour KIP1 PF07765.12 GAP86571.1 - 0.09 12.9 0.2 0.53 10.4 0.2 2.4 1 0 0 1 1 1 0 KIP1-like protein Syntaxin-6_N PF09177.11 GAP86571.1 - 0.13 12.9 1.2 1.2 9.7 0.7 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal ArabFuran-catal PF09206.11 GAP86572.1 - 1.5e-143 477.8 9.9 1.9e-143 477.5 9.9 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 GAP86572.1 - 5.4e-53 178.8 0.9 6.6e-53 178.5 0.2 1.5 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B (ABFB) domain Fasciclin PF02469.22 GAP86573.1 - 4.9e-24 85.0 0.0 3.5e-17 62.8 0.0 2.6 2 1 0 2 2 2 2 Fasciclin domain Trypan_PARP PF05887.11 GAP86573.1 - 2.4 8.2 12.3 5.7 6.9 12.3 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1690 PF07956.11 GAP86576.1 - 1e-38 132.9 9.4 1.2e-38 132.7 9.4 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Borrelia_P83 PF05262.11 GAP86576.1 - 0.02 13.4 6.7 0.024 13.2 6.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein MIEAP PF16026.5 GAP86576.1 - 0.071 13.3 2.8 0.097 12.9 2.8 1.2 1 0 0 1 1 1 0 Mitochondria-eating protein BIV_Env PF05858.12 GAP86576.1 - 0.16 10.1 0.5 0.19 9.9 0.5 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) FUSC PF04632.12 GAP86576.1 - 0.37 9.3 5.6 0.42 9.1 5.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2407_C PF13373.6 GAP86576.1 - 0.9 9.7 3.3 0.56 10.4 0.2 1.9 1 1 1 2 2 2 0 DUF2407 C-terminal domain TYW3 PF02676.14 GAP86577.1 - 8.8e-69 231.1 0.0 1.2e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 SUI1 PF01253.22 GAP86577.1 - 5.5e-27 94.1 2.4 9.6e-27 93.3 2.4 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 tRNA_synthFbeta PF17759.1 GAP86578.1 - 2.9e-44 151.1 0.0 5e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain AdoMet_MTase PF07757.13 GAP86578.1 - 5.4e-36 123.3 0.0 1.2e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase PhetRS_B1 PF18262.1 GAP86578.1 - 6.7e-28 96.7 0.0 1.6e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 GAP86578.1 - 4.3e-26 91.6 0.0 7.1e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 GAP86578.1 - 6e-18 64.9 0.2 1.5e-14 54.0 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetase B5 domain Methyltransf_32 PF13679.6 GAP86578.1 - 0.0038 17.2 0.0 0.18 11.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP86578.1 - 0.031 14.1 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Adaptin_N PF01602.20 GAP86579.1 - 4.5e-115 385.2 1.1 5.8e-115 384.8 1.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 GAP86579.1 - 2e-55 187.1 4.3 4e-55 186.1 4.3 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 GAP86579.1 - 3.6e-34 117.3 0.1 1.1e-33 115.8 0.1 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 GAP86579.1 - 9.2e-19 67.6 1.7 2.1e-12 47.2 0.0 5.5 2 1 3 5 5 5 2 HEAT repeats Cnd1 PF12717.7 GAP86579.1 - 2.9e-06 27.4 12.0 0.056 13.5 0.1 5.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 GAP86579.1 - 0.00062 20.2 0.1 1.2 10.0 0.0 4.3 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat CLASP_N PF12348.8 GAP86579.1 - 0.014 15.0 5.9 0.018 14.6 0.2 3.2 3 1 1 4 4 4 0 CLASP N terminal DUF5010 PF16402.5 GAP86579.1 - 0.022 13.6 0.1 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) RTP1_C1 PF10363.9 GAP86579.1 - 0.11 12.6 1.8 4.9 7.4 0.0 3.6 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Alpha_adaptin_C PF02296.16 GAP86579.1 - 0.15 12.3 0.0 0.55 10.4 0.0 2.0 1 1 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain HEAT PF02985.22 GAP86579.1 - 0.33 11.3 10.0 3.1 8.3 0.4 5.3 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 GAP86579.1 - 2.4 8.8 4.2 2.4 8.8 0.6 3.0 3 0 0 3 3 3 0 HEAT-like repeat CDP-OH_P_transf PF01066.21 GAP86580.1 - 1.7e-17 63.9 0.1 1.7e-17 63.9 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase bZIP_1 PF00170.21 GAP86581.1 - 3e-07 30.4 14.2 5.2e-07 29.7 14.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 GAP86581.1 - 0.00042 20.2 0.0 0.00042 20.2 0.0 2.8 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_Maf PF03131.17 GAP86581.1 - 0.0009 19.7 10.4 0.0016 18.9 10.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor SHE3 PF17078.5 GAP86581.1 - 0.0025 17.6 4.3 0.004 16.9 4.3 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 GvpL_GvpF PF06386.11 GAP86581.1 - 0.086 12.8 2.5 0.13 12.2 2.5 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF V_ATPase_I PF01496.19 GAP86581.1 - 0.09 10.7 2.4 0.13 10.2 2.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMSTEN PF07988.12 GAP86581.1 - 0.28 10.7 2.6 11 5.6 0.3 2.6 2 1 0 2 2 2 0 LMSTEN motif bZIP_2 PF07716.15 GAP86581.1 - 0.6 10.2 17.2 3.1 7.9 15.6 2.1 1 1 1 2 2 2 0 Basic region leucine zipper M PF02370.16 GAP86581.1 - 1 10.1 3.2 13 6.7 0.8 2.6 2 0 0 2 2 2 0 M protein repeat Transp_cyt_pur PF02133.15 GAP86583.1 - 8.7e-33 113.8 30.7 4.8e-32 111.3 30.7 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AA_permease_2 PF13520.6 GAP86584.1 - 2e-56 191.6 57.7 2.5e-56 191.3 57.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP86584.1 - 1e-16 60.6 44.0 1.4e-16 60.2 44.0 1.1 1 0 0 1 1 1 1 Amino acid permease Xpo1 PF08389.12 GAP86586.1 - 0.027 14.5 0.1 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Exportin 1-like protein ATP12 PF07542.11 GAP86587.1 - 1e-40 138.8 0.1 1.6e-40 138.2 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein DLH PF01738.18 GAP86590.1 - 1e-12 48.1 0.0 1.3e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family NUDIX PF00293.28 GAP86591.1 - 9.6e-08 32.1 0.3 4.8e-06 26.7 0.3 2.3 1 1 0 1 1 1 1 NUDIX domain Acyl-CoA_dh_1 PF00441.24 GAP86592.1 - 6e-32 110.9 0.4 1.8e-31 109.4 0.4 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAP86592.1 - 4.1e-30 104.7 0.2 9e-30 103.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAP86592.1 - 2.4e-26 91.8 0.2 4.1e-26 91.0 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAP86592.1 - 1.3e-12 48.2 2.9 6e-12 46.0 0.2 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAP86592.1 - 0.00025 20.8 0.2 0.00068 19.4 0.2 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.22 GAP86593.1 - 1.2e-137 459.6 0.1 1.4e-137 459.3 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain DUF1752 PF08550.10 GAP86594.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) RTC PF01137.21 GAP86595.1 - 9.5e-50 168.8 0.0 1.6e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase EST1_DNA_bind PF10373.9 GAP86596.1 - 6e-17 62.0 0.2 3.8e-12 46.3 0.1 2.4 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain DUF4719 PF15843.5 GAP86599.1 - 3.2 7.8 6.1 6.3 6.9 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) SIP1 PF04938.12 GAP86600.1 - 1.1e-09 38.3 0.1 0.0025 17.6 0.2 3.2 3 0 0 3 3 3 3 Survival motor neuron (SMN) interacting protein 1 (SIP1) RNR_inhib PF08591.10 GAP86601.1 - 1.1e-26 94.2 0.1 5.5e-26 92.0 0.0 2.2 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Med25_NR-box PF11244.8 GAP86601.1 - 0.058 13.8 0.1 0.17 12.3 0.1 1.7 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing Ribosomal_S27e PF01667.17 GAP86602.1 - 3.4e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 GAP86602.1 - 0.14 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 GAP86602.1 - 1.2 9.2 7.0 2.7 8.0 4.3 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Phosducin PF02114.16 GAP86603.1 - 1.6e-12 46.9 0.1 2.4e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 GAP86603.1 - 0.019 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin U3_assoc_6 PF08640.11 GAP86603.1 - 0.11 12.5 1.4 0.16 12.0 0.2 1.8 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 NPH-II PF12011.8 GAP86603.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase NPH-II LRR_8 PF13855.6 GAP86604.1 - 7.7e-10 38.4 6.0 7.7e-10 38.4 6.0 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 GAP86604.1 - 2.8e-06 27.6 10.5 0.00013 22.3 0.8 2.8 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAP86604.1 - 0.045 13.8 4.6 5.1 7.4 0.5 2.9 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 GAP86604.1 - 0.18 12.5 8.3 13 6.8 0.2 4.2 2 1 1 3 3 3 0 Leucine Rich Repeat SPT_ssu-like PF11779.8 GAP86605.1 - 3.5e-14 52.1 3.4 5.1e-14 51.6 3.4 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DUF1624 PF07786.12 GAP86605.1 - 0.0097 15.5 0.1 0.011 15.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) AMP-binding PF00501.28 GAP86606.1 - 4.5e-59 200.1 0.1 9.8e-46 156.2 0.0 3.2 1 1 2 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.6 GAP86606.1 - 5.9e-17 62.4 0.6 3.1e-16 60.1 0.6 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.15 GAP86607.1 - 1.9e-13 50.8 0.0 4.1e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3237 PF11578.8 GAP86610.1 - 1.1e-22 80.4 0.1 3.5e-22 78.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3237) Fungal_trans_2 PF11951.8 GAP86611.1 - 1.4e-07 30.7 0.1 8.8e-06 24.8 0.1 2.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ferric_reduct PF01794.19 GAP86612.1 - 4.3e-24 85.0 10.4 4.3e-24 85.0 10.4 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAP86612.1 - 2.1e-17 63.7 0.0 9.9e-16 58.2 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAP86612.1 - 6.1e-09 35.9 0.0 2.4e-07 30.8 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 GAP86612.1 - 0.061 14.0 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain HEAT PF02985.22 GAP86613.1 - 2.5e-14 52.1 10.5 0.0045 17.1 0.0 9.7 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.6 GAP86613.1 - 4.1e-12 46.3 1.9 8.3e-09 35.8 0.0 6.4 8 1 0 8 8 8 1 HEAT-like repeat IBN_N PF03810.19 GAP86613.1 - 6.2e-08 32.5 1.3 6.2e-08 32.5 1.3 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 GAP86613.1 - 1.8e-07 31.5 7.4 0.0006 20.1 0.1 6.0 4 2 2 7 7 7 2 HEAT repeats Arm PF00514.23 GAP86613.1 - 0.00036 20.5 0.6 74 3.6 0.1 6.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 GAP86613.1 - 0.23 11.4 4.0 14 5.6 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) DUF1548 PF07579.11 GAP86613.1 - 1.7 9.0 4.5 28 5.0 0.1 3.7 3 1 1 4 4 4 0 Domain of Unknown Function (DUF1548) Fungal_trans PF04082.18 GAP86614.1 - 1.7e-13 50.2 0.0 2.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP86614.1 - 0.014 15.5 9.7 0.024 14.7 9.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 GAP86614.1 - 2.5 8.0 19.8 3.8 7.4 19.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec2p PF06428.11 GAP86615.1 - 3.8e-28 97.3 16.9 3.8e-28 97.3 16.9 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF5401 PF17380.2 GAP86615.1 - 0.12 10.4 10.2 0.0064 14.6 4.7 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5401) Med9 PF07544.13 GAP86615.1 - 2.9 8.1 10.7 31 4.8 6.2 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 GDI PF00996.18 GAP86616.1 - 1.7e-27 96.0 0.0 1.1e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Rad21_Rec8_N PF04825.13 GAP86617.1 - 1.9e-30 105.2 0.0 3.3e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 GAP86617.1 - 1.3e-09 37.2 0.0 3.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein G5 PF07501.12 GAP86617.1 - 0.22 12.0 1.2 0.64 10.5 1.2 1.7 1 0 0 1 1 1 0 G5 domain ALO PF04030.14 GAP86618.1 - 7.6e-91 304.5 1.7 1e-90 304.1 1.7 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 GAP86618.1 - 2.7e-29 101.7 0.0 3.9e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain RNase_PH PF01138.21 GAP86620.1 - 1.9e-18 67.2 0.0 4e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAP86620.1 - 0.033 14.2 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Ferric_reduct PF01794.19 GAP86621.1 - 6.5e-18 65.0 2.8 6.5e-18 65.0 2.8 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAP86621.1 - 1.4e-12 47.7 0.1 4.9e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 GAP86621.1 - 1.7e-12 47.7 0.0 3.7e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 GAP86621.1 - 0.004 17.8 0.0 1.2 9.8 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Shadoo PF14999.6 GAP86624.1 - 4.5 7.4 10.2 8.3 6.5 0.8 2.6 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SNARE PF05739.19 GAP86626.1 - 1.5e-13 50.5 0.1 3.4e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 GAP86626.1 - 6.5e-09 34.8 1.8 8.4e-09 34.4 0.2 2.2 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 GAP86626.1 - 0.0002 21.6 2.6 0.052 13.8 0.1 3.4 3 0 0 3 3 3 1 Uncharacterized conserved protein Syntaxin PF00804.25 GAP86626.1 - 0.0025 17.5 0.6 0.0025 17.5 0.6 3.3 2 1 1 3 3 3 1 Syntaxin DUF4988 PF16378.5 GAP86626.1 - 0.0083 15.8 4.9 7.6 6.2 0.0 3.3 2 1 1 3 3 3 2 Domain of unknown function Prominin PF05478.11 GAP86626.1 - 0.01 13.9 4.9 0.45 8.4 0.1 2.2 2 0 0 2 2 2 0 Prominin Syntaxin-18_N PF10496.9 GAP86626.1 - 0.024 14.9 0.5 0.18 12.1 0.1 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF1887 PF09002.11 GAP86626.1 - 0.11 11.2 1.9 0.18 10.4 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1887) SOAR PF16533.5 GAP86626.1 - 0.23 11.5 0.2 0.23 11.5 0.2 2.3 3 0 0 3 3 3 0 STIM1 Orai1-activating region NPV_P10 PF05531.12 GAP86626.1 - 0.26 11.8 9.2 16 6.1 0.1 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein TRPM_tetra PF16519.5 GAP86626.1 - 0.26 11.4 4.3 0.43 10.7 0.8 3.1 3 0 0 3 3 3 0 Tetramerisation domain of TRPM SF-assemblin PF06705.11 GAP86626.1 - 0.41 9.9 7.9 0.067 12.5 0.9 2.5 3 0 0 3 3 3 0 SF-assemblin/beta giardin MCPsignal PF00015.21 GAP86626.1 - 0.92 9.3 10.1 0.23 11.3 1.2 2.8 3 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 GAP86626.1 - 1 9.6 5.3 2.7 8.3 0.1 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1771 PF08590.10 GAP86626.1 - 1.6 9.2 5.7 3.3 8.1 4.9 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF1771) BLOC1_2 PF10046.9 GAP86626.1 - 1.6 9.0 5.9 1.7 9.0 0.1 3.2 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 GAP86626.1 - 2.8 8.6 9.8 0.45 11.2 0.4 3.2 3 0 0 3 3 3 0 SlyX DUF1664 PF07889.12 GAP86626.1 - 3.5 7.7 7.6 1.9 8.5 0.5 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 GAP86626.1 - 8.3 7.0 10.7 0.37 11.3 0.6 2.7 3 0 0 3 3 2 0 Protein of unknown function DUF16 Aldo_ket_red PF00248.21 GAP86627.1 - 1e-39 136.5 0.0 1.4e-37 129.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family NACHT PF05729.12 GAP86628.1 - 1.8e-06 28.0 0.0 4.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAP86628.1 - 0.00062 20.1 0.1 0.0047 17.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 GAP86628.1 - 0.0048 17.4 0.0 0.049 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAP86628.1 - 0.0099 16.3 0.1 0.059 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 GAP86628.1 - 0.02 15.4 0.1 0.076 13.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 GAP86628.1 - 0.021 15.2 0.0 0.061 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 GAP86628.1 - 0.067 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GvpG PF05120.12 GAP86628.1 - 0.14 12.1 0.3 0.4 10.7 0.3 1.7 1 0 0 1 1 1 0 Gas vesicle protein G PMC2NT PF08066.12 GAP86628.1 - 0.29 11.9 1.4 2.1 9.1 0.6 2.6 2 0 0 2 2 2 0 PMC2NT (NUC016) domain AAA_23 PF13476.6 GAP86628.1 - 0.64 10.5 2.7 0.83 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ADH_N PF08240.12 GAP86629.1 - 5.8e-26 90.5 0.2 5.8e-26 90.5 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP86629.1 - 1.4e-16 60.7 0.6 1.4e-16 60.7 0.6 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAP86629.1 - 3.9e-09 36.3 3.7 0.00063 19.3 0.0 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 GAP86629.1 - 0.011 14.9 1.5 0.017 14.2 1.5 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAP86629.1 - 0.041 13.2 7.0 0.026 13.8 4.2 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAP86629.1 - 0.18 11.2 0.1 0.39 10.0 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 GAP86629.1 - 2.4 8.2 5.8 0.34 11.0 1.2 1.9 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HI0933_like PF03486.14 GAP86629.1 - 4.4 5.9 8.1 1.5 7.4 5.4 1.5 2 0 0 2 2 2 0 HI0933-like protein adh_short_C2 PF13561.6 GAP86630.1 - 1.6e-56 191.5 0.4 2.1e-56 191.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP86630.1 - 8.3e-51 172.2 1.1 1.5e-50 171.4 0.3 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAP86630.1 - 1e-14 54.9 0.5 2.4e-14 53.7 0.5 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP86630.1 - 1.3e-07 31.3 0.0 1.7e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 GAP86630.1 - 0.00068 19.1 0.4 0.0034 16.9 0.2 1.9 1 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme RmlD_sub_bind PF04321.17 GAP86630.1 - 0.0032 16.6 0.5 0.012 14.8 0.1 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 GAP86630.1 - 0.06 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 GAP86630.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 GAP86630.1 - 0.13 12.7 0.2 0.31 11.5 0.2 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF1815 PF08844.10 GAP86630.1 - 0.14 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) NmrA PF05368.13 GAP86630.1 - 0.75 9.3 4.0 0.29 10.7 0.9 1.9 2 1 0 2 2 2 0 NmrA-like family Acetyltransf_1 PF00583.25 GAP86632.1 - 1.1e-12 48.2 0.0 1.4e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP86632.1 - 3.5e-09 37.0 0.2 5.7e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAP86632.1 - 9.3e-09 35.3 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 GAP86632.1 - 0.0065 15.1 0.0 0.0091 14.6 0.0 1.1 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit Lipase_3 PF01764.25 GAP86633.1 - 2e-14 53.7 0.0 4.3e-13 49.3 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GAP86633.1 - 0.04 14.5 0.3 0.25 11.9 0.1 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP86633.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 23ISL PF16620.5 GAP86633.1 - 0.17 12.0 9.1 0.26 11.4 0.7 2.6 1 1 1 2 2 2 0 Unstructured linker between I-set domains 2 and 3 on MYLCK Glyco_hydro_43 PF04616.14 GAP86634.1 - 1.2e-21 77.2 0.3 7.3e-12 45.2 0.1 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 HET PF06985.11 GAP86635.1 - 1e-17 64.8 0.0 2.4e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 GAP86636.1 - 4.7e-45 154.0 2.8 7.6e-45 153.3 2.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP86636.1 - 1.2e-38 132.5 2.3 2e-38 131.8 2.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP86636.1 - 0.0001 22.2 2.1 0.00019 21.4 2.1 1.3 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.18 GAP86636.1 - 0.0073 16.4 4.9 0.0073 16.4 4.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 GAP86636.1 - 0.038 13.4 0.5 0.072 12.4 0.5 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-met PF12874.7 GAP86636.1 - 0.09 13.2 1.5 0.22 12.0 1.5 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type YjeF_N PF03853.15 GAP86636.1 - 0.14 12.0 1.9 0.13 12.1 0.2 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 GAP86636.1 - 0.39 10.6 2.5 0.27 11.1 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C2H2_jaz PF12171.8 GAP86636.1 - 3.7 7.9 7.2 0.17 12.2 1.3 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding p450 PF00067.22 GAP86637.1 - 9.6e-54 182.8 0.0 2.9e-51 174.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAP86638.1 - 2e-57 195.0 0.0 1.2e-55 189.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 PhyH PF05721.13 GAP86639.1 - 2.5e-23 83.5 0.0 3.2e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) InPase PF18823.1 GAP86640.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Inorganic Pyrophosphatase COX2_TM PF02790.15 GAP86640.1 - 0.77 9.9 8.5 0.18 12.0 1.5 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Methyltransf_2 PF00891.18 GAP86641.1 - 2.6e-08 33.4 0.0 0.0036 16.6 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Adeno_E3_CR2 PF02439.15 GAP86642.1 - 0.0019 17.9 0.1 0.0036 17.0 0.1 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMIE PF16038.5 GAP86642.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 TMIE protein CD34_antigen PF06365.12 GAP86642.1 - 0.21 11.2 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family TNFR_16_TM PF18422.1 GAP86642.1 - 0.27 11.2 1.2 0.5 10.4 1.2 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Epimerase PF01370.21 GAP86643.1 - 1.1e-25 90.6 0.0 1.4e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP86643.1 - 3.7e-13 49.6 0.0 5.7e-13 49.0 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAP86643.1 - 1.4e-11 43.9 0.0 2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAP86643.1 - 3.4e-10 39.5 0.0 1.8e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 GAP86643.1 - 5.8e-07 29.6 0.1 1.4e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 GAP86643.1 - 2.5e-05 23.8 0.1 4.4e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 GAP86643.1 - 7.1e-05 22.1 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 GAP86643.1 - 0.00096 18.8 0.1 0.023 14.2 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.20 GAP86643.1 - 0.001 19.2 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.10 GAP86643.1 - 0.0026 17.7 0.0 0.006 16.5 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAP86643.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Glyco_trans_4_2 PF13477.6 GAP86643.1 - 0.018 15.0 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like RmlD_sub_bind PF04321.17 GAP86643.1 - 0.02 14.0 0.0 0.044 12.9 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 GAP86643.1 - 0.028 14.7 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 GAP86644.1 - 6.8e-08 32.1 0.1 9.6e-08 31.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Mcp5_PH PF12814.7 GAP86646.1 - 4.7e-43 146.2 0.1 2.2e-42 144.0 0.0 2.3 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology zf-CCCH PF00642.24 GAP86647.1 - 1.2e-08 34.6 2.8 2.3e-08 33.7 2.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.25 GAP86647.1 - 1.6e-06 27.8 7.3 3.1e-06 26.9 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP86647.1 - 2.9e-06 27.0 4.7 5.3e-06 26.2 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP86647.1 - 5.3e-06 26.2 6.9 1e-05 25.2 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP86647.1 - 1.5e-05 24.9 8.1 3.1e-05 23.9 8.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 GAP86647.1 - 3.5e-05 23.7 7.1 7e-05 22.8 7.1 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 GAP86647.1 - 9.6e-05 22.4 3.0 0.00023 21.2 3.0 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 GAP86647.1 - 0.00018 21.4 7.3 0.00032 20.6 7.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCCH_4 PF18044.1 GAP86647.1 - 0.00021 21.0 3.6 0.0004 20.1 3.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-RING_2 PF13639.6 GAP86647.1 - 0.0032 17.8 6.6 0.0061 16.9 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 GAP86647.1 - 0.019 15.1 8.5 0.044 13.9 8.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAP86647.1 - 0.03 14.2 5.4 0.056 13.3 5.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 USP19_linker PF16602.5 GAP86647.1 - 0.24 12.0 5.8 0.056 14.0 2.0 1.9 2 0 0 2 2 2 0 Linker region of USP19 deubiquitinase zf-rbx1 PF12678.7 GAP86647.1 - 0.25 11.7 2.8 0.49 10.7 2.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-CCCH_2 PF14608.6 GAP86647.1 - 0.52 10.9 4.8 1.2 9.7 4.8 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PEP_mutase PF13714.6 GAP86648.1 - 1.3e-57 195.1 4.2 1.5e-57 194.9 4.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase AbiEi_4 PF13338.6 GAP86648.1 - 2.3 8.4 7.7 3.5 7.9 0.1 3.8 4 0 0 4 4 4 0 Transcriptional regulator, AbiEi antitoxin Gly_transf_sug PF04488.15 GAP86649.1 - 2e-09 37.9 0.0 3.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif RAC_head PF16717.5 GAP86650.1 - 6.5e-33 113.6 2.1 6.5e-33 113.6 2.1 4.2 3 1 1 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 GAP86650.1 - 3.5e-19 68.7 0.8 3.5e-19 68.7 0.8 2.6 2 1 0 2 2 2 1 DnaJ domain Complex1_LYR PF05347.15 GAP86651.1 - 0.0094 16.0 0.4 0.033 14.3 0.2 2.0 2 1 0 2 2 2 1 Complex 1 protein (LYR family) DUF3148 PF11347.8 GAP86651.1 - 0.098 12.4 0.0 7.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) RRM_1 PF00076.22 GAP86652.1 - 8.4e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAP86652.1 - 0.00027 20.9 0.1 0.00046 20.1 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 GAP86652.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 GAP86652.1 - 0.037 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif MFS_1 PF07690.16 GAP86653.1 - 2.5e-30 105.6 25.0 2.5e-30 105.6 25.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP86653.1 - 1e-06 27.9 5.0 1e-06 27.9 5.0 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter PAN_4 PF14295.6 GAP86654.1 - 0.091 12.7 1.6 0.42 10.6 0.5 2.5 2 0 0 2 2 2 0 PAN domain Fungal_trans PF04082.18 GAP86655.1 - 9.2e-11 41.3 0.0 1.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP86655.1 - 1.4e-06 28.3 11.2 2.3e-06 27.6 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 GAP86657.1 - 0.00014 21.4 0.1 0.0012 18.3 0.1 2.3 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP86657.1 - 0.00082 18.9 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 GAP86658.1 - 5.2e-28 97.8 0.0 2.3e-19 69.6 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP86658.1 - 1.5e-18 67.3 0.0 5.5e-12 45.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP86658.1 - 2.3e-08 34.2 0.0 3.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 GAP86658.1 - 0.04 14.2 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sulfotransfer_4 PF17784.1 GAP86659.1 - 9.6e-67 224.9 0.7 1.1e-66 224.7 0.7 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAP86659.1 - 0.00049 20.5 0.1 0.0008 19.8 0.1 1.5 1 1 0 1 1 1 1 Sulfotransferase family MFS_1 PF07690.16 GAP86660.1 - 8.9e-14 51.2 53.5 1e-13 51.0 31.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.24 GAP86661.1 - 2.9e-08 33.7 0.0 3.7e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pkinase PF00069.25 GAP86663.1 - 1.1e-40 139.7 0.0 8.2e-22 77.8 0.1 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86663.1 - 1.5e-14 53.9 0.4 1e-09 38.1 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP86663.1 - 0.021 13.6 0.0 0.039 12.7 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GAP86663.1 - 0.18 11.7 1.0 3.8 7.4 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family NARP1 PF12569.8 GAP86663.1 - 0.83 8.5 5.2 1.3 7.9 5.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Med26 PF08711.11 GAP86664.1 - 4e-09 36.3 0.0 9.3e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Presenilin PF01080.17 GAP86664.1 - 3.2 6.4 5.9 0.58 8.9 1.8 1.7 2 0 0 2 2 2 0 Presenilin Brr6_like_C_C PF10104.9 GAP86665.1 - 9.7e-33 112.8 0.1 1.4e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.6 GAP86665.1 - 0.08 13.3 0.7 0.33 11.4 0.7 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIA PF03153.13 GAP86665.1 - 0.15 12.0 6.5 0.3 11.0 6.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1388 PF07142.12 GAP86665.1 - 4.9 7.2 7.3 9 6.4 0.6 3.3 2 1 0 2 2 2 0 Repeat of unknown function (DUF1388) Fungal_trans PF04082.18 GAP86666.1 - 2.9e-20 72.4 1.7 3.9e-20 72.0 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP86666.1 - 5.5e-08 32.8 12.7 1.1e-07 31.8 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.7 GAP86667.1 - 6.3e-05 23.2 7.2 0.009 16.4 0.9 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAP86667.1 - 0.0014 19.3 17.8 0.025 15.4 2.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP86667.1 - 0.0069 16.7 1.8 0.0069 16.7 1.8 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.8 GAP86667.1 - 0.023 14.5 3.4 0.17 11.7 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) zf-H2C2_2 PF13465.6 GAP86667.1 - 0.024 15.1 6.1 0.89 10.1 0.5 3.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 GAP86667.1 - 0.14 12.6 14.7 0.06 13.8 1.7 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 GAP86667.1 - 0.21 11.5 6.6 1.2 9.1 0.7 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Mut7-C PF01927.16 GAP86667.1 - 4.9 7.2 6.5 58 3.8 6.5 2.3 1 1 0 1 1 1 0 Mut7-C RNAse domain Arylsulfotran_2 PF14269.6 GAP86668.1 - 4.9e-52 177.2 0.0 6.7e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 GAP86668.1 - 1e-15 57.5 0.0 2.4e-15 56.4 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Globin PF00042.22 GAP86669.1 - 9.8e-09 35.8 0.0 1.6e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 GAP86669.1 - 1.7e-07 31.8 0.0 3.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAP86669.1 - 0.00026 21.3 0.0 0.0037 17.6 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 GAP86669.1 - 0.0004 20.3 0.1 0.00064 19.6 0.1 1.3 1 0 0 1 1 1 1 Protoglobin FAD_binding_8 PF08022.12 GAP86669.1 - 0.0063 16.6 0.0 0.031 14.4 0.0 2.0 1 1 1 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 GAP86669.1 - 0.0086 16.2 0.1 1.1 9.3 0.0 2.8 2 1 1 3 3 3 1 Ferric reductase NAD binding domain DUF3431 PF11913.8 GAP86670.1 - 4.2e-87 291.5 0.0 5.3e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) UQ_con PF00179.26 GAP86672.1 - 5.2e-10 39.1 0.0 9.3e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like PF12937.7 GAP86672.1 - 0.0014 18.5 0.1 0.003 17.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP86672.1 - 0.013 15.3 0.3 0.037 13.9 0.3 1.7 1 0 0 1 1 1 0 F-box domain RWD PF05773.22 GAP86672.1 - 0.015 15.6 0.3 0.031 14.6 0.3 1.5 1 0 0 1 1 1 0 RWD domain GST_C_2 PF13410.6 GAP86673.1 - 7e-05 22.8 0.1 0.00015 21.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAP86673.1 - 0.00014 22.2 0.0 0.00028 21.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP86673.1 - 0.0018 18.5 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAP86673.1 - 0.0087 16.3 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAP86673.1 - 0.024 15.0 0.0 0.3 11.5 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain FAD_binding_3 PF01494.19 GAP86674.1 - 0.14 11.4 3.3 0.17 11.1 0.1 2.3 3 0 0 3 3 3 0 FAD binding domain SAICAR_synt PF01259.18 GAP86675.1 - 1.4e-93 313.2 0.0 1.6e-93 313.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Cutinase PF01083.22 GAP86676.1 - 4.7e-41 140.7 0.2 5.6e-41 140.4 0.2 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAP86676.1 - 0.0015 18.1 0.1 0.0023 17.5 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 GAP86676.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_3 PF07859.13 GAP86676.1 - 0.12 12.2 1.5 0.37 10.6 0.7 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 GAP86676.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AltA1 PF16541.5 GAP86677.1 - 7.8e-07 29.9 0.1 0.085 13.7 0.0 2.5 2 0 0 2 2 2 2 Alternaria alternata allergen 1 zinc_ribbon_10 PF10058.9 GAP86678.1 - 3.8e-18 64.9 0.1 6.7e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein CCDC-167 PF15188.6 GAP86678.1 - 0.0065 16.8 2.2 0.042 14.2 0.0 2.5 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 167 FlaC_arch PF05377.11 GAP86678.1 - 0.1 13.0 0.7 0.43 11.0 0.1 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ima1_N PF09779.9 GAP86678.1 - 3.6 8.5 5.5 0.91 10.4 0.6 2.6 2 1 1 3 3 3 0 Ima1 N-terminal domain GRIP PF01465.20 GAP86679.1 - 4.3e-10 39.3 0.1 1.1e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 GRIP domain DHR10 PF18595.1 GAP86679.1 - 0.0024 17.9 9.9 0.0024 17.9 9.9 9.0 3 2 8 11 11 11 2 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 GAP86679.1 - 0.97 9.9 0.0 0.97 9.9 0.0 7.1 6 2 1 7 7 7 0 Nucleopolyhedrovirus P10 protein Shugoshin_N PF07558.11 GAP86679.1 - 9.4 6.2 20.0 2 8.4 0.8 5.4 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Sugar_tr PF00083.24 GAP86681.1 - 3e-81 273.6 18.8 3.4e-81 273.4 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP86681.1 - 1.4e-24 86.7 29.8 7.4e-22 77.7 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAP86681.1 - 0.00019 20.0 1.6 0.00037 19.0 1.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Amidohydro_1 PF01979.20 GAP86682.1 - 7.2e-55 186.7 0.0 8.5e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAP86682.1 - 5.7e-13 49.1 0.0 6.1e-09 35.9 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family A_deaminase PF00962.22 GAP86682.1 - 0.00041 19.8 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase tRNA-synt_2 PF00152.20 GAP86683.1 - 3.4e-77 259.6 0.4 4.5e-77 259.2 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 GAP86683.1 - 4.5e-06 26.3 0.3 0.0086 15.6 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 GAP86683.1 - 2.1e-05 24.4 0.0 4.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2492 PF10678.9 GAP86683.1 - 0.053 13.8 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) Aft1_OSA PF11785.8 GAP86683.1 - 0.15 12.5 2.5 0.39 11.2 0.5 2.5 2 0 0 2 2 2 0 Aft1 osmotic stress response (OSM) domain Borrelia_P83 PF05262.11 GAP86683.1 - 4.5 5.7 10.3 6.2 5.2 10.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S49_N PF08496.10 GAP86683.1 - 4.6 7.3 7.1 10 6.2 7.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Trypan_PARP PF05887.11 GAP86684.1 - 0.0071 16.3 2.3 0.0096 15.9 2.3 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Herpes_UL25 PF01499.16 GAP86684.1 - 0.015 13.9 4.1 0.017 13.7 4.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DTHCT PF08070.11 GAP86685.1 - 0.15 12.8 9.1 0.24 12.2 9.1 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region Glyco_hydro_17 PF00332.18 GAP86687.1 - 5.5e-08 32.8 1.3 6.5e-06 26.0 0.2 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 SARAF PF06682.12 GAP86687.1 - 0.093 12.4 0.0 0.093 12.4 0.0 2.5 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SNARE PF05739.19 GAP86687.1 - 0.11 12.5 1.1 0.23 11.5 1.1 1.5 1 0 0 1 1 1 0 SNARE domain Trypan_PARP PF05887.11 GAP86688.1 - 1.5 8.8 15.0 0.16 12.0 3.8 3.0 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Toxin_35 PF10530.9 GAP86689.1 - 0.18 11.8 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold Cytochrom_B562 PF07361.11 GAP86690.1 - 0.013 16.1 0.7 0.075 13.7 0.0 2.4 3 0 0 3 3 3 0 Cytochrome b562 DUF3929 PF13066.6 GAP86690.1 - 6.5 6.9 7.7 2.4 8.2 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3929) WD40 PF00400.32 GAP86691.1 - 6.3e-21 74.3 12.0 6.7e-09 36.2 0.2 5.8 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP86691.1 - 2e-07 31.2 0.0 0.12 12.7 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP86691.1 - 6.5e-05 22.1 0.0 0.047 12.6 0.0 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pro_Al_protease PF02983.14 GAP86691.1 - 0.1 12.7 0.4 0.1 12.7 0.4 2.3 3 0 0 3 3 3 0 Alpha-lytic protease prodomain Nup160 PF11715.8 GAP86691.1 - 0.13 10.9 0.1 5.8 5.4 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PUL PF08324.11 GAP86692.1 - 1e-58 198.8 2.7 1.5e-58 198.2 2.7 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 GAP86692.1 - 5.6e-43 145.8 1.8 9.6e-43 145.0 1.8 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 GAP86692.1 - 4.2e-30 103.4 2.8 9.3e-07 29.5 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 GAP86692.1 - 0.012 15.6 0.0 11 6.1 0.0 3.9 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 GAP86692.1 - 0.082 11.5 0.1 1.4 7.5 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 GAP86692.1 - 0.2 12.2 0.7 2.2 8.9 0.0 3.1 2 1 1 3 3 3 0 PQQ-like domain SRR1 PF07985.12 GAP86694.1 - 5.6e-17 61.5 0.0 9.9e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 Peptidase_C48 PF02902.19 GAP86695.1 - 4.5e-08 33.2 0.0 6.4e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-RING_2 PF13639.6 GAP86696.1 - 2e-08 34.4 4.8 2e-08 34.4 4.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 GAP86696.1 - 2e-05 24.5 2.4 5e-05 23.2 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.6 GAP86696.1 - 4.7e-05 23.2 8.2 6.7e-05 22.7 3.4 2.3 1 1 2 3 3 3 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 GAP86696.1 - 5.7e-05 23.1 2.3 5.7e-05 23.1 2.3 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 GAP86696.1 - 0.00015 21.9 4.6 0.00038 20.6 4.6 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.29 GAP86696.1 - 0.00019 21.3 5.3 0.00035 20.4 5.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.6 GAP86696.1 - 0.0036 17.2 4.8 0.0036 17.2 4.8 2.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_4 PF14570.6 GAP86696.1 - 0.0039 16.9 7.4 0.0068 16.2 5.4 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 GAP86696.1 - 0.0044 17.3 5.5 0.0044 17.3 5.5 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 GAP86696.1 - 0.02 14.7 4.8 0.02 14.7 4.8 2.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 GAP86696.1 - 0.024 14.7 5.2 0.049 13.8 5.2 1.6 1 0 0 1 1 1 0 RING-variant domain DNA_ligase_ZBD PF03119.16 GAP86696.1 - 0.087 12.9 2.5 8.8 6.5 0.1 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Rad50_zn_hook PF04423.14 GAP86696.1 - 0.38 10.6 2.4 2.1 8.3 0.2 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif Glyco_hydro_92 PF07971.12 GAP86697.1 - 7.8e-147 489.9 0.0 9.6e-147 489.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAP86697.1 - 2.7e-51 174.8 0.1 4.9e-51 173.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Ank_2 PF12796.7 GAP86698.1 - 1.1e-71 237.4 0.0 2.2e-17 63.4 0.0 7.3 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP86698.1 - 5.1e-54 180.0 2.3 4.5e-10 39.9 0.0 11.1 2 1 8 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP86698.1 - 1.3e-53 172.7 3.1 0.00086 19.6 0.0 14.3 14 0 0 14 14 14 12 Ankyrin repeat Ank PF00023.30 GAP86698.1 - 4.6e-53 175.5 3.5 0.00022 21.5 0.0 13.1 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 GAP86698.1 - 4.3e-46 154.4 9.8 7.6e-09 35.7 0.0 10.0 2 2 7 10 10 10 10 Ankyrin repeats (many copies) NACHT PF05729.12 GAP86698.1 - 2.4e-09 37.3 0.0 6.7e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 GAP86698.1 - 0.00087 19.7 0.0 0.0039 17.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAP86698.1 - 0.0055 17.0 0.0 0.022 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF948 PF06103.11 GAP86698.1 - 0.011 16.0 4.2 0.34 11.2 2.0 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) AAA_16 PF13191.6 GAP86698.1 - 0.032 14.6 0.0 0.2 12.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain SesA PF17107.5 GAP86698.1 - 0.033 14.4 0.9 0.14 12.3 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1664 PF07889.12 GAP86698.1 - 0.061 13.4 6.7 0.23 11.5 0.4 3.4 3 1 2 5 5 4 0 Protein of unknown function (DUF1664) COG2 PF06148.11 GAP86698.1 - 0.1 12.7 1.4 0.27 11.3 0.3 2.3 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_5 PF07728.14 GAP86698.1 - 0.22 11.5 0.5 14 5.7 0.0 3.7 5 1 1 6 6 6 0 AAA domain (dynein-related subfamily) FlaC_arch PF05377.11 GAP86698.1 - 0.22 12.0 5.3 15 6.1 0.0 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 GAP86698.1 - 0.59 10.6 5.9 1.7 9.1 1.2 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 GAP86698.1 - 0.91 9.5 7.3 2.2 8.3 1.3 3.4 3 0 0 3 3 3 0 Laminin Domain II Ferritin_2 PF13668.6 GAP86699.1 - 0.00028 21.1 0.1 0.013 15.7 0.1 2.2 1 1 0 1 1 1 1 Ferritin-like domain WD40 PF00400.32 GAP86700.1 - 2.1e-11 44.1 3.0 0.49 11.3 0.0 6.6 5 1 1 6 6 6 4 WD domain, G-beta repeat CDC45 PF02724.14 GAP86700.1 - 0.22 9.8 18.6 0.33 9.2 18.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 GAP86700.1 - 0.27 10.0 7.4 0.43 9.3 7.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AAA_12 PF13087.6 GAP86701.1 - 3.9e-35 121.3 0.0 7.1e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAP86701.1 - 6.6e-25 88.4 0.5 7.6e-15 55.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAP86701.1 - 1.7e-09 38.1 0.0 3.3e-08 34.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAP86701.1 - 1.7e-08 34.4 0.0 1.6e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GAP86701.1 - 9.2e-05 22.3 0.0 0.1 12.3 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 GAP86701.1 - 0.0012 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAP86701.1 - 0.0043 16.8 0.1 0.0096 15.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 GAP86701.1 - 0.0064 15.8 0.3 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 GAP86701.1 - 0.0068 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.21 GAP86701.1 - 0.021 14.4 0.1 0.81 9.1 0.0 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ATPase PF06745.13 GAP86701.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 GAP86701.1 - 0.093 13.1 0.1 0.34 11.3 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 GAP86701.1 - 0.15 12.1 0.0 0.77 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2235 PF09994.9 GAP86702.1 - 2.2e-82 276.7 0.1 3e-82 276.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 GAP86702.1 - 4.5e-05 23.5 0.2 0.00011 22.1 0.0 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_M28 PF04389.17 GAP86703.1 - 1.6e-25 90.0 0.0 2.3e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAP86703.1 - 1.9e-08 34.3 0.1 9.6e-08 32.0 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 TMEM154 PF15102.6 GAP86704.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family HET PF06985.11 GAP86705.1 - 3.5e-19 69.6 0.0 7.1e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) YjeF_N PF03853.15 GAP86706.1 - 2e-33 115.7 0.0 2.5e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus HTH_20 PF12840.7 GAP86706.1 - 0.16 12.0 0.2 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_S16 PF00886.19 GAP86707.1 - 2.7e-25 88.2 0.1 4.5e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 CPSase_L_D2 PF02786.17 GAP86708.1 - 2e-73 246.4 0.0 3.2e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 GAP86708.1 - 5.9e-37 126.1 0.0 1.3e-36 125.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 GAP86708.1 - 1.1e-36 125.7 0.0 2.1e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 GAP86708.1 - 7.3e-17 61.0 3.5 1.1e-16 60.4 1.1 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAP86708.1 - 8.5e-09 35.1 0.0 0.0005 19.8 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 GAP86708.1 - 2.7e-05 23.8 0.0 7.1e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 GAP86708.1 - 0.00039 20.5 0.0 0.00078 19.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 GAP86708.1 - 0.0034 17.0 0.0 0.018 14.6 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 GAP86708.1 - 0.0047 17.6 0.1 4.4 8.1 0.0 3.3 3 0 0 3 3 3 1 HlyD family secretion protein ATPgrasp_ST PF14397.6 GAP86708.1 - 0.028 13.7 0.0 0.096 11.9 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 GAP86708.1 - 0.13 11.4 0.0 9.2 5.4 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Putative_PNPOx PF01243.20 GAP86709.1 - 1e-13 51.3 0.0 8.4e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 GAP86709.1 - 0.0075 16.3 0.0 0.095 12.7 0.0 2.2 1 1 1 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.14 GAP86709.1 - 0.099 11.1 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Ank_2 PF12796.7 GAP86710.1 - 3.6e-51 171.7 0.0 5.5e-09 36.5 0.0 6.6 5 1 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP86710.1 - 5.5e-40 135.3 0.0 2.5e-05 24.7 0.0 10.4 7 4 4 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP86710.1 - 3.8e-35 115.9 6.5 0.0033 17.8 0.0 13.6 14 0 0 14 14 14 8 Ankyrin repeat Ank_5 PF13857.6 GAP86710.1 - 8.6e-34 115.2 5.7 0.00066 19.9 0.0 8.9 7 2 1 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 GAP86710.1 - 9e-28 95.5 7.5 0.0064 16.9 0.0 12.3 14 1 1 15 15 15 7 Ankyrin repeat FCD PF07729.12 GAP86710.1 - 0.046 14.2 1.6 6.2 7.3 0.1 4.2 3 2 0 3 3 3 0 FCD domain Ada3 PF10198.9 GAP86711.1 - 0.29 11.3 5.5 0.18 12.0 3.0 1.8 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 DUF349 PF03993.12 GAP86711.1 - 1 9.7 8.0 3.9 7.8 8.0 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) HSP70 PF00012.20 GAP86712.1 - 1.2e-08 33.6 0.6 0.0002 19.7 0.1 3.0 3 0 0 3 3 3 3 Hsp70 protein BPL_LplA_LipB PF03099.19 GAP86713.1 - 2.3e-05 24.3 0.0 4.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Peptidase_C65 PF10275.9 GAP86714.1 - 2.7e-64 217.0 0.0 4.8e-64 216.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase C65 Otubain Zip PF02535.22 GAP86714.1 - 0.011 15.0 1.3 0.022 14.0 1.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 GAP86714.1 - 1 9.3 24.1 0.015 15.3 16.9 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 GAP86714.1 - 1.1 8.0 7.1 1.7 7.3 7.1 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 GAP86714.1 - 1.2 9.2 3.5 2.4 8.2 3.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spem1 PF15670.5 GAP86714.1 - 1.6 8.2 12.2 2.6 7.6 12.2 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 PAT1 PF09770.9 GAP86714.1 - 5.4 5.2 19.6 7.6 4.7 19.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 GAP86714.1 - 8.2 6.0 24.5 18 4.8 24.5 1.5 1 0 0 1 1 1 0 Spt20 family Acetyltransf_3 PF13302.7 GAP86717.1 - 9.8e-29 100.8 0.0 1.3e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP86717.1 - 1.3e-05 25.4 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.10 GAP86717.1 - 0.17 11.9 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein GDC-P PF02347.16 GAP86718.1 - 2.3e-177 590.1 0.0 2.7e-160 533.9 0.0 3.0 3 1 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 GAP86718.1 - 6.5e-08 31.9 0.0 0.00025 20.1 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 GAP86718.1 - 1.4e-06 27.9 0.0 2.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 GAP86718.1 - 0.16 10.5 0.0 4.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Nup54 PF13874.6 GAP86719.1 - 2.1e-40 138.1 0.5 2.1e-40 138.1 0.5 3.0 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 GAP86719.1 - 2.9e-14 52.3 5.8 2.9e-14 52.3 5.8 1.7 2 0 0 2 2 2 1 NUP57/Nup54 C-terminal domain DUF2722 PF10846.8 GAP86719.1 - 0.00099 18.2 9.6 0.0014 17.6 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DivIVA PF05103.13 GAP86719.1 - 0.0062 16.6 2.5 0.0062 16.6 2.5 3.1 2 1 1 3 3 3 1 DivIVA protein Adhesin_P1_N PF18652.1 GAP86719.1 - 0.036 14.1 2.1 0.036 14.1 2.1 2.5 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain Spt20 PF12090.8 GAP86719.1 - 0.76 9.3 24.7 0.19 11.3 21.2 1.7 2 0 0 2 2 2 0 Spt20 family Nucleoporin_FG PF13634.6 GAP86719.1 - 1.9 9.4 33.1 12 6.8 33.1 2.0 1 1 0 1 1 1 0 Nucleoporin FG repeat region RAB3GAP2_N PF14655.6 GAP86719.1 - 2.4 7.4 7.0 4.5 6.4 7.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4834 PF16118.5 GAP86719.1 - 6.9 7.7 9.5 1.5 9.8 5.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3484 PF11983.8 GAP86719.1 - 9.1 7.5 14.5 28 5.9 9.9 2.6 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch CHCH PF06747.13 GAP86720.1 - 1.7e-11 43.9 11.8 1.5e-09 37.7 5.9 2.4 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 GAP86720.1 - 0.00014 21.8 8.1 0.00031 20.7 3.6 2.2 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 GAP86720.1 - 0.0074 16.3 10.3 0.38 10.8 3.7 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3455 PF11937.8 GAP86720.1 - 0.12 12.7 0.1 0.18 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Pet191_N PF10203.9 GAP86720.1 - 0.23 11.8 6.5 6.6 7.1 0.0 2.9 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 GAP86720.1 - 3.1 8.1 11.6 8.3 6.7 4.4 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb CAP PF00188.26 GAP86721.1 - 6.8e-16 59.3 4.2 9.8e-16 58.7 4.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Lin-8 PF03353.15 GAP86721.1 - 0.13 11.8 0.3 0.17 11.4 0.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DLH PF01738.18 GAP86722.1 - 5.1e-23 81.8 0.0 1.2e-22 80.5 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAP86722.1 - 0.1 11.8 0.0 0.48 9.6 0.0 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 peroxidase PF00141.23 GAP86723.1 - 7.8e-16 58.5 0.1 1.1e-15 58.0 0.1 1.2 1 0 0 1 1 1 1 Peroxidase FAA_hydrolase PF01557.18 GAP86724.1 - 4.9e-55 186.5 0.0 1.1e-54 185.4 0.0 1.4 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 GAP86724.1 - 2.6e-32 111.2 0.1 4.6e-32 110.4 0.1 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.18 GAP86725.1 - 1.9e-17 63.2 2.0 1.3e-16 60.5 0.0 2.8 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP86725.1 - 2.2e-08 34.1 8.0 3.9e-08 33.3 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.9 GAP86725.1 - 4.6 5.7 11.7 6.7 5.1 11.7 1.2 1 0 0 1 1 1 0 Macoilin family NST1 PF13945.6 GAP86725.1 - 8.2 6.5 14.8 20 5.2 14.8 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator Methyltransf_25 PF13649.6 GAP86726.1 - 1.1e-09 38.9 0.0 6.6e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 GAP86726.1 - 5.9e-09 36.5 0.0 2.6e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP86726.1 - 4.2e-05 24.2 0.0 8.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP86726.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAP86726.1 - 0.063 13.1 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.19 GAP86727.1 - 5.9e-13 48.8 2.7 1.3e-05 24.7 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAP86727.1 - 4.5e-05 22.8 0.1 0.037 13.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP86727.1 - 0.00046 20.7 0.0 0.0019 18.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP86727.1 - 0.0027 17.9 0.0 0.0077 16.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 GAP86727.1 - 0.049 13.6 0.2 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 GAP86727.1 - 0.08 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HgmA PF04209.13 GAP86728.1 - 8.7e-193 640.8 0.0 1e-192 640.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DPPIV_N PF00930.21 GAP86729.1 - 1.3e-108 363.0 1.1 2e-108 362.3 1.1 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 GAP86729.1 - 1.4e-38 132.5 1.8 2.2e-38 131.9 1.0 1.6 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAP86729.1 - 0.015 15.0 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP86729.1 - 0.02 15.5 0.1 0.058 14.0 0.1 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family PD40 PF07676.12 GAP86729.1 - 0.025 14.5 0.1 0.44 10.6 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF2920 PF11144.8 GAP86729.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DCX PF03607.17 GAP86730.1 - 0.063 13.4 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Doublecortin DUF3747 PF12565.8 GAP86732.1 - 0.058 12.7 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) PFL-like PF02901.15 GAP86733.1 - 4.4e-121 405.6 0.0 6.3e-121 405.1 0.0 1.1 1 0 0 1 1 1 1 Pyruvate formate lyase-like Dyp_perox PF04261.12 GAP86733.1 - 1.8e-25 89.6 0.0 3e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Dyp-type peroxidase family Gly_radical PF01228.21 GAP86733.1 - 0.17 12.4 0.0 0.48 11.0 0.0 1.7 1 0 0 1 1 1 0 Glycine radical Chlorosome_CsmC PF11098.8 GAP86735.1 - 0.0081 16.2 6.2 0.0098 15.9 6.2 1.1 1 0 0 1 1 1 1 Chlorosome envelope protein C Senescence PF06911.12 GAP86735.1 - 0.018 15.4 5.0 1.8 8.8 0.0 2.1 1 1 0 2 2 2 0 Senescence-associated protein PGAP1 PF07819.13 GAP86736.1 - 0.00049 19.9 0.0 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAP86736.1 - 0.0024 18.5 0.4 0.015 15.9 0.2 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 GAP86736.1 - 0.027 14.0 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ank_2 PF12796.7 GAP86737.1 - 5.8e-90 296.0 21.5 2e-15 57.1 0.0 13.2 5 2 10 16 16 16 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP86737.1 - 6e-59 195.7 15.5 1.6e-07 31.7 0.0 15.5 14 3 2 16 16 16 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP86737.1 - 5.6e-55 182.7 26.3 7.6e-07 29.3 0.1 17.4 13 4 5 18 18 18 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP86737.1 - 7.4e-42 136.5 16.7 0.03 14.9 0.0 20.9 23 0 0 23 23 23 9 Ankyrin repeat Ank PF00023.30 GAP86737.1 - 5.2e-41 137.4 22.4 1.2e-05 25.5 0.0 16.6 18 0 0 18 18 18 7 Ankyrin repeat SPRY PF00622.28 GAP86737.1 - 1.7e-16 60.4 0.2 6.8e-16 58.5 0.3 2.0 3 0 0 3 3 3 1 SPRY domain Tmemb_40 PF10160.9 GAP86737.1 - 0.014 14.9 0.5 0.024 14.1 0.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein DUF1843 PF08898.10 GAP86737.1 - 0.14 12.7 0.5 5 7.7 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) DUF3659 PF12396.8 GAP86738.1 - 3.6e-142 462.4 96.1 5e-22 77.6 1.5 12.7 11 2 1 12 12 12 11 Protein of unknown function (DUF3659) Trypan_PARP PF05887.11 GAP86738.1 - 0.012 15.6 4.1 0.012 15.6 4.1 7.5 7 1 1 8 8 8 0 Procyclic acidic repetitive protein (PARP) BPL_C PF02237.17 GAP86738.1 - 0.02 14.8 5.6 21 5.1 0.1 4.6 3 0 0 3 3 3 0 Biotin protein ligase C terminal domain 2C_adapt PF08793.10 GAP86738.1 - 0.096 12.9 0.1 10 6.4 0.0 3.7 3 0 0 3 3 3 0 2-cysteine adaptor domain Adeno_E1A PF02703.14 GAP86738.1 - 0.32 10.6 4.1 0.26 10.8 0.3 2.3 2 0 0 2 2 2 0 Early E1A protein SPESP1 PF15754.5 GAP86738.1 - 8.6 5.4 8.4 4.3 6.4 3.0 2.4 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 DUF3659 PF12396.8 GAP86739.1 - 2.1e-16 59.6 7.0 1.8e-10 40.6 5.8 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) DUF1673 PF07895.11 GAP86740.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) LAP1C PF05609.12 GAP86740.1 - 0.23 10.5 22.7 0.29 10.2 22.7 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF1062 PF06353.12 GAP86740.1 - 8.3 7.2 8.0 0.34 11.7 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) SQHop_cyclase_N PF13249.6 GAP86741.1 - 0.036 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain WD40 PF00400.32 GAP86744.1 - 3.8e-41 138.3 17.1 8.9e-07 29.5 0.3 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 GAP86744.1 - 3.6e-11 42.8 0.9 1.7e-10 40.6 0.2 2.3 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 GAP86744.1 - 9e-09 35.5 0.4 2.1 8.7 0.0 5.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GAP86744.1 - 2.7e-08 33.5 0.3 2.7e-08 33.5 0.3 2.2 2 1 0 2 2 2 1 F-box domain Nup160 PF11715.8 GAP86744.1 - 6.9e-05 21.7 5.4 2.2 6.8 0.0 5.1 3 1 2 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 GAP86744.1 - 0.0029 17.2 1.4 2.4 7.7 0.1 3.0 2 1 0 3 3 3 2 PQQ-like domain DUF4597 PF15366.6 GAP86744.1 - 0.072 12.8 0.3 0.91 9.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) F-box_4 PF15966.5 GAP86744.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 F-box DEAD PF00270.29 GAP86745.1 - 6.5e-20 71.6 0.0 1.6e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP86745.1 - 2.6e-18 66.4 0.1 2.8e-15 56.6 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 GAP86745.1 - 6e-05 23.1 0.0 0.0002 21.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 GAP86745.1 - 9.9e-05 23.0 0.7 0.00029 21.5 0.7 1.8 1 0 0 1 1 1 1 RecQ zinc-binding SNF2_N PF00176.23 GAP86745.1 - 0.0058 15.4 0.0 0.01 14.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AbiJ_NTD3 PF18860.1 GAP86745.1 - 0.053 13.1 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 AbiJ N-terminal domain 3 Tyrosinase PF00264.20 GAP86746.1 - 6.6e-46 157.4 1.9 1e-45 156.7 1.9 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DiS_P_DiS PF06750.13 GAP86746.1 - 0.0034 17.5 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain GST_N PF02798.20 GAP86747.1 - 1.3e-11 44.7 0.0 2.1e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAP86747.1 - 4.7e-09 36.5 0.0 8.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP86747.1 - 1.7e-08 34.4 0.2 4.2e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAP86747.1 - 9.2e-07 29.1 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP86747.1 - 9.6e-07 28.9 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAP86747.1 - 5.7e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAP86747.1 - 0.0024 18.4 0.0 0.0086 16.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain adh_short PF00106.25 GAP86748.1 - 5.1e-18 65.2 0.0 2.5e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAP86748.1 - 8.3e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Phosphoesterase PF04185.14 GAP86749.1 - 1.2e-34 120.0 0.2 7.4e-34 117.5 0.0 2.1 1 1 1 2 2 2 1 Phosphoesterase family NUC153 PF08159.12 GAP86749.1 - 0.13 12.1 0.2 0.36 10.7 0.2 1.8 1 0 0 1 1 1 0 NUC153 domain Sugar_tr PF00083.24 GAP86750.1 - 6e-85 285.8 14.5 6.8e-85 285.6 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP86750.1 - 3.5e-26 92.0 16.2 5e-26 91.5 16.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 GAP86750.1 - 8.2e-05 21.3 9.1 0.0028 16.3 2.3 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein PTR2 PF00854.21 GAP86750.1 - 0.97 8.2 10.6 0.25 10.1 3.7 2.2 2 0 0 2 2 2 0 POT family OATP PF03137.20 GAP86750.1 - 2.1 6.5 10.7 1.9 6.6 1.3 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Dynamin_N PF00350.23 GAP86751.1 - 1.8e-18 67.2 0.0 1.4e-17 64.2 0.0 2.3 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 GAP86751.1 - 3.6e-08 33.0 0.1 1.2e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Nefa_Nip30_N PF10187.9 GAP86751.1 - 0.025 14.9 0.7 0.067 13.6 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF5595 PF18077.1 GAP86751.1 - 0.046 13.8 0.3 0.19 11.9 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) GED PF02212.18 GAP86751.1 - 0.057 13.6 1.2 0.48 10.6 0.0 2.7 2 1 1 3 3 3 0 Dynamin GTPase effector domain RPAP1_N PF08621.10 GAP86751.1 - 0.1 12.4 0.6 0.4 10.5 0.6 2.0 1 0 0 1 1 1 0 RPAP1-like, N-terminal MMR_HSR1 PF01926.23 GAP86751.1 - 0.12 12.5 0.0 1.2 9.3 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 GAP86751.1 - 0.21 11.6 1.5 28 4.7 0.5 2.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PAP2 PF01569.21 GAP86752.1 - 4.4e-28 97.7 0.5 4.4e-28 97.7 0.5 2.2 2 0 0 2 2 2 1 PAP2 superfamily CbtA PF09490.10 GAP86752.1 - 0.0072 16.1 0.4 0.018 14.8 0.1 1.8 2 0 0 2 2 2 1 Probable cobalt transporter subunit (CbtA) Pox_P21 PF05313.12 GAP86752.1 - 0.063 12.9 0.2 0.15 11.6 0.1 1.6 2 0 0 2 2 2 0 Poxvirus P21 membrane protein O-antigen_lig PF13425.6 GAP86752.1 - 0.25 10.1 2.2 0.37 9.5 2.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3302 PF11742.8 GAP86752.1 - 9.5 6.4 7.5 3.5 7.8 2.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3302) WW PF00397.26 GAP86753.1 - 1e-08 35.1 5.9 1e-08 35.1 5.9 2.2 2 0 0 2 2 2 1 WW domain FF PF01846.19 GAP86753.1 - 1.2e-08 35.0 0.2 1.2e-08 35.0 0.2 2.8 3 0 0 3 3 3 1 FF domain DUF5641 PF18701.1 GAP86753.1 - 0.3 11.3 7.6 0.13 12.5 1.8 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5641) DLH PF01738.18 GAP86754.1 - 2.5e-27 95.8 0.0 3e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family ENT PF03735.14 GAP86754.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 ENT domain TraQ PF09679.10 GAP86755.1 - 0.39 10.7 1.7 0.55 10.2 0.1 2.0 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Bestrophin PF01062.21 GAP86756.1 - 2.8e-33 115.6 0.0 6.1e-33 114.5 0.0 1.4 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF3730 PF12530.8 GAP86756.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) zf-U1 PF06220.12 GAP86758.1 - 6.2e-07 29.1 0.7 9.9e-07 28.4 0.7 1.3 1 0 0 1 1 1 1 U1 zinc finger GA PF01468.17 GAP86758.1 - 0.046 14.0 1.2 0.15 12.3 1.2 1.9 1 0 0 1 1 1 0 GA module Herpes_pp85 PF04637.12 GAP86758.1 - 0.081 11.3 0.6 0.13 10.7 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4554 PF15091.6 GAP86758.1 - 0.11 11.4 2.0 0.16 10.8 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) HAUS6_N PF14661.6 GAP86758.1 - 1.6 8.3 5.1 0.47 10.0 1.9 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus PIR PF00399.19 GAP86759.1 - 0.045 13.3 0.2 0.045 13.3 0.2 3.3 3 0 0 3 3 3 0 Yeast PIR protein repeat HEAT_EZ PF13513.6 GAP86760.1 - 3.6e-16 59.3 19.5 3.4e-07 30.6 0.1 10.3 9 2 2 11 11 11 3 HEAT-like repeat HEAT_2 PF13646.6 GAP86760.1 - 2e-15 56.9 12.8 0.029 14.8 0.0 8.9 6 4 2 9 9 9 4 HEAT repeats HEAT PF02985.22 GAP86760.1 - 4.7e-15 54.4 10.4 0.0018 18.4 0.0 9.1 10 0 0 10 10 9 3 HEAT repeat IBN_N PF03810.19 GAP86760.1 - 7e-13 48.3 0.1 1.1e-09 38.1 0.0 3.1 2 0 0 2 2 2 2 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 GAP86760.1 - 1.3e-08 35.3 0.2 0.15 12.7 0.0 5.8 3 3 1 5 5 5 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 GAP86760.1 - 4.1e-06 26.6 8.1 1 9.5 0.0 7.3 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 GAP86760.1 - 1.2e-05 25.4 1.5 0.87 9.6 0.0 4.6 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF577 PF04510.12 GAP86760.1 - 0.00052 20.0 0.2 0.03 14.2 0.2 3.3 3 0 0 3 3 3 1 Family of unknown function (DUF577) MMS19_C PF12460.8 GAP86760.1 - 0.0012 18.1 9.3 0.044 12.9 0.1 5.1 4 3 2 6 6 6 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 GAP86760.1 - 0.0023 17.6 0.0 0.058 13.0 0.0 3.1 2 1 0 2 2 2 1 CLASP N terminal ParcG PF10274.9 GAP86760.1 - 0.0032 17.6 0.3 0.15 12.1 0.1 3.3 3 1 1 4 4 4 1 Parkin co-regulated protein Dopey_N PF04118.14 GAP86760.1 - 0.0075 15.4 0.9 6.6 5.7 0.0 4.0 3 1 0 4 4 4 1 Dopey, N-terminal RIX1 PF08167.12 GAP86760.1 - 0.013 15.3 0.1 2.1 8.0 0.0 4.1 3 2 0 3 3 3 0 rRNA processing/ribosome biogenesis FlaF PF07309.11 GAP86760.1 - 0.11 12.6 0.0 0.48 10.5 0.0 2.2 1 0 0 1 1 1 0 Flagellar protein FlaF HEAT_PBS PF03130.16 GAP86760.1 - 0.13 13.1 5.0 26 5.8 0.1 5.1 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat TEA PF01285.18 GAP86760.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 TEA/ATTS domain UNC45-central PF11701.8 GAP86760.1 - 0.14 12.1 2.7 1.1 9.2 0.9 3.3 2 1 2 4 4 4 0 Myosin-binding striated muscle assembly central Importin_rep_6 PF18829.1 GAP86760.1 - 0.22 11.6 3.1 2.6 8.2 0.0 3.5 3 0 0 3 3 3 0 Importin repeat 6 Vitellogenin_N PF01347.22 GAP86760.1 - 0.43 8.9 1.2 0.64 8.3 0.2 1.8 2 1 0 2 2 2 0 Lipoprotein amino terminal region RTP1_C1 PF10363.9 GAP86760.1 - 0.57 10.4 2.4 20 5.4 0.1 4.5 4 2 0 4 4 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Drf_DAD PF06345.11 GAP86760.1 - 3.1 8.0 6.0 0.59 10.3 1.0 2.5 2 0 0 2 2 2 0 DRF Autoregulatory Domain IF-2B PF01008.17 GAP86761.1 - 2.5e-24 86.0 0.0 3.3e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 GAP86761.1 - 1.6e-10 41.1 0.0 3.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Peptidase_M36 PF02128.15 GAP86762.1 - 3.4e-159 529.9 8.6 4.4e-159 529.6 8.6 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 GAP86762.1 - 1.8e-17 62.9 0.7 5e-17 61.5 0.7 1.8 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 GAP86762.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain AMP-binding PF00501.28 GAP86763.1 - 1.2e-216 719.3 0.0 1.7e-77 260.8 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 GAP86763.1 - 1.8e-174 580.7 0.0 1.8e-36 125.8 0.0 6.4 6 1 0 6 6 6 6 Condensation domain PP-binding PF00550.25 GAP86763.1 - 1.8e-58 194.7 9.1 1.5e-11 44.5 0.0 7.2 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAP86763.1 - 3e-08 34.5 0.0 0.002 19.1 0.0 3.8 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 GAP86763.1 - 1e-06 27.7 0.0 0.69 8.5 0.0 4.4 4 0 0 4 4 4 3 Transferase family K_oxygenase PF13434.6 GAP86764.1 - 2.8e-108 362.1 0.0 1.7e-107 359.5 0.0 1.8 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAP86764.1 - 6.2e-06 25.7 0.0 6.6e-05 22.3 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP86764.1 - 0.00019 20.8 0.0 0.0044 16.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F_bP_aldolase PF01116.20 GAP86765.1 - 1.7e-90 303.3 0.0 1.9e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II zf-Nse PF11789.8 GAP86767.1 - 3.5e-17 62.0 1.3 6.1e-17 61.2 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 GAP86767.1 - 0.00031 20.7 0.5 0.00054 19.9 0.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAP86767.1 - 0.021 14.7 0.5 0.04 13.8 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CENP-O PF09496.10 GAP86767.1 - 0.049 13.6 1.3 0.11 12.5 1.3 1.6 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component zf-MIZ PF02891.20 GAP86767.1 - 0.15 11.8 0.5 0.27 11.0 0.5 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Use1 PF09753.9 GAP86767.1 - 2.2 8.0 10.4 1.1 8.9 4.2 2.2 2 0 0 2 2 2 0 Membrane fusion protein Use1 MR_MLE_C PF13378.6 GAP86769.1 - 1.7e-58 197.8 0.2 4e-58 196.6 0.0 1.6 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAP86769.1 - 0.0012 19.0 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 GAP86769.1 - 0.0037 16.4 0.0 0.0057 15.9 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Glyco_transf_29 PF00777.18 GAP86770.1 - 0.19 11.1 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) DAO PF01266.24 GAP86771.1 - 9.8e-30 104.3 0.4 2.8e-29 102.8 0.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 GAP86771.1 - 0.00028 20.1 0.1 0.0011 18.2 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 GAP86771.1 - 0.0029 17.8 0.0 0.0097 16.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP86771.1 - 0.018 14.3 0.0 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP86771.1 - 0.018 15.0 0.0 0.073 13.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 GAP86771.1 - 0.12 11.2 0.0 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Ring_hydroxyl_A PF00848.19 GAP86772.1 - 5.2e-22 78.9 4.1 1e-11 45.3 1.2 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 GAP86772.1 - 5.3e-15 55.1 0.0 1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fungal_trans PF04082.18 GAP86773.1 - 8.6e-11 41.4 2.0 1.6e-10 40.4 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP86773.1 - 6.9e-09 35.7 10.3 1.4e-08 34.7 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCV_T PF01571.21 GAP86774.1 - 2.5e-69 233.5 0.0 4.4e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 GAP86774.1 - 2.5e-45 155.6 1.1 4e-45 154.9 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 GAP86774.1 - 2.3e-23 81.9 0.1 6.5e-23 80.5 0.1 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 GAP86774.1 - 1.8e-16 60.2 0.0 4.2e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 GAP86774.1 - 1.3e-05 24.6 0.5 0.12 11.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP86774.1 - 2e-05 25.0 0.2 0.015 15.8 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP86774.1 - 0.0002 20.6 0.1 0.00031 19.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 GAP86774.1 - 0.00092 18.2 0.3 0.055 12.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.18 GAP86774.1 - 0.0052 17.0 0.2 0.014 15.6 0.2 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_9 PF13454.6 GAP86774.1 - 0.008 16.2 0.2 0.23 11.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 GAP86774.1 - 0.015 15.4 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 GAP86774.1 - 0.077 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 GAP86774.1 - 0.19 11.0 0.6 2 7.6 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Flavoprotein PF02441.19 GAP86775.1 - 1.7e-19 70.2 0.1 3e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Flavoprotein WD40 PF00400.32 GAP86778.1 - 1e-23 83.1 19.0 1.5e-05 25.6 0.1 7.0 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP86778.1 - 2.1e-13 50.4 3.6 3e-05 24.2 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 GAP86778.1 - 8.5e-05 22.6 9.5 0.035 14.0 0.2 3.1 2 2 1 3 3 3 2 Transcription factor IIIC subunit delta N-term ECH_1 PF00378.20 GAP86781.1 - 1.4e-34 119.6 1.2 1.1e-21 77.3 0.6 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAP86781.1 - 1.4e-17 64.2 0.1 2.4e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase adh_short PF00106.25 GAP86782.1 - 5.9e-35 120.5 0.0 1.2e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase HET PF06985.11 GAP86782.1 - 5.7e-28 98.1 0.1 1.1e-27 97.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 GAP86782.1 - 2.2e-26 92.8 0.0 3.4e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAP86782.1 - 1.6e-07 31.0 0.0 6.2e-06 25.8 0.0 2.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 GAP86782.1 - 1.8e-07 31.3 0.0 3.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAP86782.1 - 5.4e-05 23.2 0.0 0.00018 21.5 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAP86782.1 - 0.02 14.4 0.0 0.046 13.2 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAP86782.1 - 0.046 13.3 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_Gly3P_dh_N PF01210.23 GAP86782.1 - 0.063 13.3 0.0 19 5.2 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DFP PF04127.15 GAP86782.1 - 0.13 12.1 0.0 0.73 9.6 0.0 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein bZIP_1 PF00170.21 GAP86783.1 - 2e-06 27.8 6.3 3.5e-06 27.0 6.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAP86783.1 - 8.4e-06 25.8 9.4 1.5e-05 25.0 9.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper TTKRSYEDQ PF10212.9 GAP86783.1 - 0.042 12.8 0.4 0.062 12.3 0.4 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.17 GAP86783.1 - 0.093 13.3 4.0 0.2 12.2 4.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor ABC_tran PF00005.27 GAP86784.1 - 5.1e-47 159.8 0.1 9.1e-23 81.3 0.0 3.5 3 1 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 GAP86784.1 - 6.3e-19 67.8 6.7 6.3e-19 67.8 6.7 3.6 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 GAP86784.1 - 8.6e-18 65.2 3.5 0.0002 21.3 0.0 4.6 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAP86784.1 - 5.1e-11 42.4 4.4 0.0031 17.0 0.0 4.8 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAP86784.1 - 5.4e-07 29.7 0.2 0.01 15.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 GAP86784.1 - 6.8e-07 29.9 0.1 0.071 13.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 GAP86784.1 - 3.4e-06 26.7 0.4 0.066 13.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAP86784.1 - 5.8e-06 26.3 2.0 0.079 12.9 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 GAP86784.1 - 1.9e-05 24.9 0.0 0.15 12.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 GAP86784.1 - 2.2e-05 25.0 16.4 0.0048 17.4 0.1 4.4 5 0 0 5 5 4 2 AAA domain AAA_30 PF13604.6 GAP86784.1 - 3e-05 23.8 0.4 0.011 15.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 GAP86784.1 - 7.3e-05 23.2 0.0 0.23 11.9 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP86784.1 - 0.00017 22.0 5.4 0.42 11.0 1.3 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 GAP86784.1 - 0.00025 21.2 0.1 0.64 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 GAP86784.1 - 0.00035 20.6 0.0 1.1 9.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 GAP86784.1 - 0.00082 19.2 1.4 1.2 8.8 0.2 3.2 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 GAP86784.1 - 0.00098 18.9 12.1 0.12 12.1 0.2 4.6 5 0 0 5 5 5 2 AAA ATPase domain Roc PF08477.13 GAP86784.1 - 0.0013 19.0 0.1 1.1 9.4 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 GAP86784.1 - 0.0017 18.3 0.1 2.3 8.1 0.1 2.5 2 0 0 2 2 2 2 NACHT domain MeaB PF03308.16 GAP86784.1 - 0.0025 16.9 0.2 0.82 8.6 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 GAP86784.1 - 0.0025 18.2 0.0 2.2 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 GAP86784.1 - 0.0026 17.7 0.1 0.45 10.4 0.1 2.8 2 0 0 2 2 2 1 NTPase AAA_7 PF12775.7 GAP86784.1 - 0.0034 16.9 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 GAP86784.1 - 0.0038 17.5 4.5 0.28 11.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 GAP86784.1 - 0.0038 16.8 0.9 0.97 9.0 0.4 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 GAP86784.1 - 0.0054 16.7 0.1 5.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_27 PF13514.6 GAP86784.1 - 0.0066 16.1 2.3 3.7 7.1 0.0 3.4 5 0 0 5 5 2 2 AAA domain MobB PF03205.14 GAP86784.1 - 0.0069 16.3 0.4 0.25 11.3 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 GAP86784.1 - 0.0076 16.3 0.2 3.2 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 GAP86784.1 - 0.017 14.3 0.1 2.8 7.0 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 GAP86784.1 - 0.034 13.8 0.1 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 GAP86784.1 - 0.05 13.2 0.0 3.2 7.3 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 GAP86784.1 - 0.064 13.3 0.2 6.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 GAP86784.1 - 0.15 11.5 0.1 2 7.9 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF87 PF01935.17 GAP86784.1 - 0.27 11.3 9.9 0.52 10.4 0.0 3.8 4 0 0 4 4 4 0 Helicase HerA, central domain Zeta_toxin PF06414.12 GAP86784.1 - 0.3 10.3 3.0 5.1 6.3 0.2 3.1 3 0 0 3 3 3 0 Zeta toxin Dynamin_N PF00350.23 GAP86784.1 - 1 9.4 10.3 16 5.5 0.0 4.5 4 1 0 4 4 4 0 Dynamin family AAA_17 PF13207.6 GAP86784.1 - 1 9.8 5.8 21 5.5 0.2 3.7 4 0 0 4 4 3 0 AAA domain ATP-synt_ab PF00006.25 GAP86786.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ORC6 PF05460.13 GAP86787.1 - 9.3 5.4 26.5 5.8 6.1 1.1 3.9 3 1 0 3 3 3 0 Origin recognition complex subunit 6 (ORC6) Tubulin PF00091.25 GAP86788.1 - 6.2e-68 228.9 0.0 1.3e-67 227.8 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 GAP86788.1 - 4.5e-43 146.4 0.1 7.3e-43 145.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 GAP86788.1 - 3.8e-05 24.0 0.0 9.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 GAP86788.1 - 0.0019 17.5 0.0 0.029 13.6 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 GAP86788.1 - 0.0037 17.0 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Pyr_redox_2 PF07992.14 GAP86789.1 - 7.5e-35 120.6 0.1 1.7e-31 109.5 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 GAP86789.1 - 1.4e-16 60.5 6.3 5.2e-12 45.9 5.5 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 GAP86789.1 - 5.1e-11 42.4 0.1 1.3e-05 25.0 0.0 3.1 3 0 0 3 3 3 2 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 GAP86789.1 - 4.4e-10 39.4 0.0 0.00062 19.7 0.0 2.7 2 0 0 2 2 2 2 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.27 GAP86789.1 - 1.6e-07 31.8 0.9 0.00066 20.2 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.17 GAP86789.1 - 1.8e-07 30.9 0.0 3.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain NIR_SIR PF01077.22 GAP86789.1 - 3.4e-07 29.9 0.0 3e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rubredoxin_C PF18267.1 GAP86789.1 - 1.5e-05 24.9 0.1 0.21 11.5 0.0 3.5 3 1 1 4 4 4 2 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 GAP86789.1 - 0.0014 18.0 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP86789.1 - 0.08 12.9 2.7 8.8 6.3 0.1 3.0 2 1 0 3 3 3 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 GAP86789.1 - 0.19 11.0 0.5 5.1 6.3 0.1 2.4 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase Pex19 PF04614.12 GAP86789.1 - 0.25 11.1 0.0 0.46 10.2 0.0 1.3 1 0 0 1 1 1 0 Pex19 protein family Pkinase PF00069.25 GAP86790.1 - 2.3e-60 204.2 0.0 2.9e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86790.1 - 4.2e-32 111.4 0.0 5.8e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP86790.1 - 0.00024 20.5 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAP86790.1 - 0.0017 18.3 1.1 0.0035 17.3 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAP86790.1 - 0.0038 16.6 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAP86790.1 - 0.054 12.3 0.0 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Ifi-6-16 PF06140.13 GAP86791.1 - 5.7e-07 29.4 15.5 9.7e-07 28.6 15.5 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family E1-E2_ATPase PF00122.20 GAP86791.1 - 2.9 7.4 5.9 6.7 6.2 5.9 1.6 1 1 0 1 1 1 0 E1-E2 ATPase NACHT PF05729.12 GAP86792.1 - 2.4e-08 34.1 0.0 7.7e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP86792.1 - 1.1e-05 25.9 0.7 0.0008 19.8 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAP86792.1 - 3e-05 24.3 0.3 0.0055 17.0 0.0 3.9 5 0 0 5 5 5 1 AAA domain Helo_like_N PF17111.5 GAP86792.1 - 0.0012 18.3 0.6 0.0069 15.8 0.2 2.2 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 GAP86792.1 - 0.0081 16.4 0.1 0.076 13.2 0.1 2.6 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Mito_fiss_reg PF05308.11 GAP86792.1 - 0.036 14.1 0.2 0.067 13.3 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA_24 PF13479.6 GAP86792.1 - 0.04 13.6 0.1 4.2 7.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain HalX PF08663.10 GAP86792.1 - 0.044 14.1 2.2 72 3.8 0.0 3.9 3 0 0 3 3 3 0 HalX domain Vps5 PF09325.10 GAP86792.1 - 0.14 11.7 3.7 2 7.9 0.5 2.6 2 0 0 2 2 2 0 Vps5 C terminal like RNA_helicase PF00910.22 GAP86792.1 - 0.15 12.5 0.1 0.62 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Cob_adeno_trans PF01923.18 GAP86792.1 - 0.2 11.8 1.9 0.89 9.7 1.0 2.5 3 0 0 3 3 3 0 Cobalamin adenosyltransferase NPV_P10 PF05531.12 GAP86792.1 - 0.27 11.7 1.5 10 6.7 0.0 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2524 PF10732.9 GAP86792.1 - 0.28 11.5 2.7 1 9.7 2.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) FlxA PF14282.6 GAP86792.1 - 1.5 8.9 5.2 0.76 9.8 2.6 1.8 2 0 0 2 2 2 0 FlxA-like protein ABC_tran_CTD PF16326.5 GAP86792.1 - 4.1 7.7 5.5 60 4.0 0.3 3.5 2 1 2 4 4 4 0 ABC transporter C-terminal domain MFS_1 PF07690.16 GAP86793.1 - 9.6e-35 120.1 43.3 9.6e-35 120.1 43.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP86793.1 - 3.1e-18 65.5 22.0 4.4e-18 65.0 22.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1056 PF06341.11 GAP86793.1 - 0.0052 17.1 4.8 0.073 13.4 0.7 3.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1056) DUF423 PF04241.15 GAP86793.1 - 0.071 13.3 8.0 0.39 11.0 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF423) MRAP PF15183.6 GAP86793.1 - 1.3 9.0 4.2 5.6 7.0 0.3 2.9 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family PAP1 PF08601.10 GAP86794.1 - 2.3e-82 277.7 51.2 1.3e-56 193.0 6.2 3.3 1 1 2 3 3 3 3 Transcription factor PAP1 bZIP_1 PF00170.21 GAP86794.1 - 1.8e-08 34.3 15.8 4.2e-08 33.2 15.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor TolA_bind_tri PF16331.5 GAP86794.1 - 0.0099 15.9 2.1 0.022 14.8 2.1 1.6 1 0 0 1 1 1 1 TolA binding protein trimerisation SHE3 PF17078.5 GAP86794.1 - 0.012 15.4 6.6 0.012 15.4 6.6 1.5 2 0 0 2 2 1 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 GAP86794.1 - 0.021 15.3 11.3 0.04 14.4 11.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor FlaC_arch PF05377.11 GAP86794.1 - 0.062 13.7 2.3 0.12 12.8 2.3 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 GAP86794.1 - 0.068 13.7 8.8 0.13 12.8 8.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region bZIP_2 PF07716.15 GAP86794.1 - 0.07 13.2 17.7 0.19 11.8 17.0 1.9 1 1 0 1 1 1 0 Basic region leucine zipper dsrm PF00035.26 GAP86794.1 - 0.1 13.3 0.3 0.26 12.0 0.3 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF812 PF05667.11 GAP86794.1 - 0.1 11.5 8.8 0.15 10.9 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 GAP86794.1 - 0.14 11.5 8.7 0.22 10.8 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop53 PF07767.11 GAP86794.1 - 0.14 11.5 20.3 0.27 10.6 20.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) YabA PF06156.13 GAP86794.1 - 0.25 12.0 1.8 0.55 10.9 1.8 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DUF3584 PF12128.8 GAP86794.1 - 0.26 8.8 7.6 0.36 8.3 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ALMT PF11744.8 GAP86794.1 - 0.36 9.6 4.9 0.55 9.0 4.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Prefoldin_2 PF01920.20 GAP86794.1 - 0.58 10.1 7.8 1.2 9.1 7.8 1.5 1 0 0 1 1 1 0 Prefoldin subunit V_ATPase_I PF01496.19 GAP86794.1 - 0.78 7.6 2.9 1.3 6.8 2.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2514 PF10721.9 GAP86794.1 - 1.2 9.2 5.4 2.4 8.2 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) UPF0242 PF06785.11 GAP86794.1 - 1.2 9.2 7.6 2 8.5 7.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 GAP86794.1 - 2.3 7.4 3.7 3.5 6.8 3.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein NAM-associated PF14303.6 GAP86794.1 - 6.5 7.5 30.4 0.16 12.7 14.4 2.7 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain BSD PF03909.17 GAP86795.1 - 1.4e-18 66.7 0.2 2.5e-18 65.8 0.2 1.5 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 GAP86795.1 - 1.1 9.2 9.8 0.081 12.9 4.6 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) V-ATPase_G PF03179.15 GAP86795.1 - 2.4 8.7 9.0 2.3 8.8 4.7 2.5 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit WGG PF10273.9 GAP86796.1 - 2.3e-31 108.3 0.4 3.6e-31 107.7 0.4 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 YL1 PF05764.13 GAP86796.1 - 1.8 8.6 6.4 2.4 8.2 6.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Abhydrolase_3 PF07859.13 GAP86797.1 - 3.7e-42 144.6 0.0 2.7e-32 112.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP86797.1 - 7.1e-14 51.5 0.0 5.3e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 GAP86797.1 - 0.0053 15.7 0.4 0.078 11.8 0.4 2.2 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 GAP86797.1 - 0.016 14.4 0.0 0.044 13.1 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MRP-L27 PF09809.9 GAP86798.1 - 8.8e-19 67.4 0.4 1.8e-18 66.4 0.4 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.13 GAP86799.1 - 3.5e-176 588.1 71.7 3.5e-176 588.1 71.7 2.1 1 1 1 2 2 2 1 Utp14 protein DUF1604 PF07713.13 GAP86800.1 - 4e-41 138.7 1.8 1.3e-40 137.1 1.8 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 GAP86800.1 - 1.7e-06 27.8 4.2 9e-06 25.5 0.7 3.2 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 GAP86800.1 - 0.0045 17.0 0.8 0.0045 17.0 0.8 3.6 4 1 0 4 4 4 1 G-patch domain HET PF06985.11 GAP86801.1 - 2.7e-49 167.3 0.7 1.5e-26 93.5 0.2 3.7 3 0 0 3 3 3 2 Heterokaryon incompatibility protein (HET) AAA PF00004.29 GAP86804.1 - 0.0023 18.3 0.0 0.0049 17.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PNP_UDP_1 PF01048.20 GAP86805.1 - 1.6e-37 129.0 0.2 2.1e-37 128.6 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily FAD_binding_4 PF01565.23 GAP86806.1 - 3.7e-21 75.3 1.1 5.8e-21 74.7 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP86806.1 - 7.5e-07 29.2 0.6 1.7e-06 28.0 0.6 1.6 1 0 0 1 1 1 1 Berberine and berberine like Atx10homo_assoc PF09759.9 GAP86807.1 - 3.5e-10 39.8 0.2 4.7e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain ARID PF01388.21 GAP86809.1 - 1.4e-16 60.9 0.1 3.7e-16 59.6 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 GAP86809.1 - 0.0015 19.1 0.0 0.003 18.1 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Arm PF00514.23 GAP86809.1 - 0.0034 17.4 0.2 0.4 10.8 0.0 2.8 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat SEN1_N PF12726.7 GAP86809.1 - 0.066 11.4 0.2 0.098 10.9 0.2 1.2 1 0 0 1 1 1 0 SEN1 N terminal SOG2 PF10428.9 GAP86809.1 - 0.56 9.3 8.1 0.96 8.6 8.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DLL_N PF12413.8 GAP86809.1 - 8.4 7.7 8.6 19 6.6 0.2 2.5 2 0 0 2 2 2 0 Homeobox protein distal-less-like N terminal KH_1 PF00013.29 GAP86810.1 - 1.2e-89 294.2 24.9 9.4e-13 47.8 0.1 13.5 14 1 0 14 14 14 9 KH domain KH_2 PF07650.17 GAP86810.1 - 1.5e-10 40.8 21.7 0.015 15.1 0.8 7.8 7 1 1 8 8 8 5 KH domain SLS PF14611.6 GAP86810.1 - 7.7e-09 35.7 6.7 0.43 10.4 0.0 7.0 3 2 4 8 8 8 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 GAP86810.1 - 7.9e-06 25.7 2.9 0.012 15.4 0.2 5.5 5 0 0 5 5 5 1 KH domain BON PF04972.17 GAP86810.1 - 0.049 14.0 1.3 5.3 7.4 0.0 3.6 3 0 0 3 3 3 0 BON domain Pkinase PF00069.25 GAP86811.1 - 9.3e-70 235.0 0.0 9.3e-70 235.0 0.0 2.3 2 0 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86811.1 - 7e-45 153.3 0.0 7e-45 153.3 0.0 2.0 2 0 0 2 2 1 1 Protein tyrosine kinase PBD PF00786.28 GAP86811.1 - 1.9e-16 60.2 0.0 1.9e-16 60.2 0.0 3.4 3 2 0 3 3 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 GAP86811.1 - 1.3e-07 30.7 13.0 2.1e-06 26.8 0.0 3.1 3 0 0 3 3 3 2 Fungal protein kinase Kinase-like PF14531.6 GAP86811.1 - 2.6e-06 27.0 0.0 2.6e-06 27.0 0.0 2.2 2 0 0 2 2 1 1 Kinase-like DDHD PF02862.17 GAP86811.1 - 0.0006 20.0 4.5 0.0006 20.0 4.5 3.2 3 0 0 3 3 3 1 DDHD domain LMBR1 PF04791.16 GAP86811.1 - 0.17 10.8 2.4 0.3 9.9 2.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Zip PF02535.22 GAP86811.1 - 0.79 8.9 11.9 0.087 12.0 2.7 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter FTA2 PF13095.6 GAP86811.1 - 0.82 9.2 0.0 0.82 9.2 0.0 2.9 4 0 0 4 4 2 0 Kinetochore Sim4 complex subunit FTA2 SID-1_RNA_chan PF13965.6 GAP86811.1 - 1.1 7.6 5.9 1.9 6.8 5.9 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 KRTAP PF11759.8 GAP86811.1 - 1.1 9.9 6.6 2.8 8.5 6.6 1.6 1 0 0 1 1 1 0 Keratin-associated matrix Cellulose_synt PF03552.14 GAP86811.1 - 2.4 6.5 3.9 4 5.8 3.9 1.2 1 0 0 1 1 1 0 Cellulose synthase EPL1 PF10513.9 GAP86811.1 - 2.6 8.4 30.5 0.037 14.4 12.1 3.4 3 0 0 3 3 3 0 Enhancer of polycomb-like CDC45 PF02724.14 GAP86811.1 - 2.6 6.2 23.3 0.055 11.8 8.9 2.4 3 0 0 3 3 3 0 CDC45-like protein Neur_chan_memb PF02932.16 GAP86811.1 - 5.6 7.0 26.9 0.01 15.9 6.1 3.4 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region adh_short_C2 PF13561.6 GAP86812.1 - 5.8e-62 209.3 1.2 8.2e-62 208.8 1.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP86812.1 - 3.6e-51 173.4 1.0 5.3e-51 172.9 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP86812.1 - 1.2e-11 44.9 0.9 1.5e-11 44.5 0.3 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAP86812.1 - 0.00019 21.0 0.2 0.00058 19.4 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.22 GAP86812.1 - 0.012 15.7 1.0 0.026 14.6 0.3 2.0 2 0 0 2 2 2 0 PA domain Polysacc_synt_2 PF02719.15 GAP86812.1 - 0.015 14.4 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 GAP86812.1 - 0.024 15.3 0.1 0.059 14.1 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain GDP_Man_Dehyd PF16363.5 GAP86812.1 - 0.067 12.6 0.1 0.12 11.8 0.1 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF2530 PF10745.9 GAP86813.1 - 0.15 12.3 2.3 0.76 10.1 2.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Glyco_hydro_31 PF01055.26 GAP86814.1 - 3.7e-106 355.9 0.1 4.5e-106 355.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAP86814.1 - 1.3e-14 54.2 0.2 6e-14 52.1 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_3 PF00933.21 GAP86815.1 - 2.6e-57 194.6 0.0 3.6e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAP86815.1 - 1.1e-52 179.0 0.0 2e-52 178.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 GAP86815.1 - 2.2e-23 82.1 1.4 3e-23 81.7 0.3 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.18 GAP86815.1 - 0.00012 22.3 0.6 0.00045 20.5 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF11 Sugar-bind PF04198.13 GAP86815.1 - 0.053 12.7 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain CARDB PF07705.11 GAP86815.1 - 0.099 12.9 0.2 0.23 11.8 0.2 1.5 1 0 0 1 1 1 0 CARDB ToxS PF17323.2 GAP86815.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Trans-membrane regulatory protein ToxS UQ_con PF00179.26 GAP86816.1 - 3e-14 52.8 0.0 3.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Complex1_LYR PF05347.15 GAP86817.1 - 0.00011 22.2 0.0 0.00029 20.8 0.0 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAP86817.1 - 0.13 13.0 0.1 0.53 11.1 0.0 2.0 2 0 0 2 2 2 0 Complex1_LYR-like SlyX PF04102.12 GAP86817.1 - 7 7.4 7.0 3.8 8.2 1.5 2.6 3 0 0 3 3 3 0 SlyX bZIP_1 PF00170.21 GAP86818.1 - 6e-06 26.3 0.8 1.4e-05 25.1 0.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2722 PF10846.8 GAP86818.1 - 4.8e-05 22.5 27.7 0.00067 18.7 13.4 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF2722) TMEM51 PF15345.6 GAP86818.1 - 0.093 12.6 21.1 4.9 6.9 0.7 3.4 3 0 0 3 3 3 0 Transmembrane protein 51 DUF4770 PF15994.5 GAP86818.1 - 0.6 10.3 24.7 5.9 7.1 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) DUF3347 PF11827.8 GAP86818.1 - 0.71 10.0 16.2 7.8 6.6 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3347) Spt20 PF12090.8 GAP86818.1 - 1.7 8.2 56.3 1.3 8.6 5.0 3.5 3 0 0 3 3 3 0 Spt20 family EPL1 PF10513.9 GAP86818.1 - 1.9 8.9 19.5 3.7 7.9 9.3 3.4 3 0 0 3 3 3 0 Enhancer of polycomb-like EOS1 PF12326.8 GAP86818.1 - 4.2 7.3 4.7 66 3.4 2.2 3.0 3 0 0 3 3 3 0 N-glycosylation protein FAD_binding_3 PF01494.19 GAP86819.1 - 6.6e-21 74.9 0.4 5.6e-17 62.0 0.1 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAP86819.1 - 8.5e-06 25.2 0.4 0.00015 21.1 0.4 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP86819.1 - 3e-05 23.8 4.3 0.00045 19.9 1.5 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 GAP86819.1 - 9.6e-05 21.6 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 GAP86819.1 - 0.00013 22.2 0.3 0.00034 20.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAP86819.1 - 0.00024 20.1 0.1 0.52 9.1 0.1 2.8 3 0 0 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.24 GAP86819.1 - 0.0012 18.0 0.1 0.0021 17.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAP86819.1 - 0.0094 14.7 0.1 0.016 14.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 GAP86819.1 - 0.089 12.1 0.3 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 GAP86819.1 - 0.11 11.5 0.5 4.5 6.2 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 GAP86819.1 - 0.16 11.2 0.7 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 GAP86819.1 - 0.2 10.9 1.1 0.34 10.1 0.2 1.7 2 0 0 2 2 2 0 Thi4 family CRAL_TRIO PF00650.20 GAP86820.1 - 5.6e-24 84.7 0.0 7.1e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAP86820.1 - 0.0045 17.2 0.0 0.0081 16.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Peptidase_M54 PF07998.11 GAP86821.1 - 3.9e-11 43.3 0.0 9.8e-11 42.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M54 Zincin_1 PF06262.11 GAP86821.1 - 0.0018 18.4 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 Zincin-like metallopeptidase Reprolysin PF01421.19 GAP86821.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.6 GAP86821.1 - 0.077 13.5 0.0 0.2 12.2 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAP86821.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 GAP86821.1 - 0.2 11.3 0.3 0.33 10.5 0.3 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 GAP86821.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Matrixin Metallopep PF12044.8 GAP86821.1 - 0.29 9.7 0.4 0.44 9.1 0.4 1.1 1 0 0 1 1 1 0 Putative peptidase family DUF4345 PF14248.6 GAP86824.1 - 0.0087 15.9 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) Chal_sti_synt_N PF00195.19 GAP86825.1 - 7e-16 58.3 0.0 7.9e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 GAP86825.1 - 2.4e-05 23.8 0.0 2.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Thiolase_N PF00108.23 GAP86825.1 - 0.0025 17.2 0.1 0.0035 16.8 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Chal_sti_synt_C PF02797.15 GAP86826.1 - 9.5e-08 32.2 0.0 1.3e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Asparaginase_2 PF01112.18 GAP86827.1 - 8.6e-70 235.2 3.3 1.1e-69 234.9 3.3 1.0 1 0 0 1 1 1 1 Asparaginase Pectate_lyase_3 PF12708.7 GAP86828.1 - 8.4e-101 336.3 19.9 4.6e-84 281.6 6.9 2.8 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAP86828.1 - 1.4e-07 31.1 3.2 0.0017 18.0 0.4 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF2190 PF09956.9 GAP86828.1 - 2.4 8.7 8.3 0.99 9.9 1.8 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2190) E1-E2_ATPase PF00122.20 GAP86829.1 - 1.6e-37 128.8 6.1 5.3e-28 97.8 0.0 3.5 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAP86829.1 - 1.6e-22 80.1 8.7 1.6e-22 80.1 8.7 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Goodbye PF17109.5 GAP86829.1 - 5.6e-22 78.5 0.0 1.6e-21 77.0 0.0 1.9 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Cation_ATPase_N PF00690.26 GAP86829.1 - 1e-16 60.4 0.1 1e-16 60.4 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 GAP86829.1 - 1.3e-12 48.4 0.1 7.5e-12 46.0 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAP86829.1 - 0.00011 22.0 0.3 0.00029 20.7 0.3 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 GAP86829.1 - 0.006 17.0 0.3 0.057 13.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain CbiA PF01656.23 GAP86829.1 - 0.033 14.2 0.1 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CHASE3 PF05227.13 GAP86829.1 - 0.17 11.8 0.8 9 6.2 0.0 3.3 3 0 0 3 3 3 0 CHASE3 domain Glyco_hydro_61 PF03443.14 GAP86830.1 - 1.2e-58 198.4 0.1 1.5e-58 198.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 GAP86831.1 - 4.9e-28 98.1 31.1 4.9e-28 98.1 31.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily HTH_psq PF05225.16 GAP86831.1 - 6.5e-14 51.4 0.2 1e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 GAP86831.1 - 1e-06 28.7 0.3 2.5e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Adeno_E1A PF02703.14 GAP86831.1 - 0.19 11.3 2.2 0.18 11.4 0.3 1.8 2 0 0 2 2 2 0 Early E1A protein Pam16 PF03656.13 GAP86832.1 - 5e-33 113.8 0.2 6.1e-33 113.5 0.2 1.0 1 0 0 1 1 1 1 Pam16 BPL_N PF09825.9 GAP86833.1 - 3.7e-146 487.0 0.0 4.5e-146 486.8 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 GAP86833.1 - 4.6e-25 88.0 0.0 7.4e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Mgm101p PF06420.12 GAP86834.1 - 1.1e-86 288.7 0.0 1.4e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 TB2_DP1_HVA22 PF03134.19 GAP86835.1 - 8.9e-25 86.4 6.7 1.4e-24 85.8 6.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GFA PF04828.14 GAP86836.1 - 1e-21 77.1 0.1 1.6e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.16 GAP86836.1 - 0.014 15.6 0.6 0.1 12.9 0.0 2.1 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RNA_POL_M_15KD PF02150.16 GAP86836.1 - 0.075 12.9 1.4 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit HECT_2 PF09814.9 GAP86836.1 - 0.14 11.0 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding HET PF06985.11 GAP86837.1 - 1.4e-28 100.1 0.0 2.2e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Velvet PF11754.8 GAP86838.1 - 1.4e-35 123.5 2.1 4.3e-26 92.4 0.4 3.6 2 2 1 3 3 3 2 Velvet factor GST_N_4 PF17172.4 GAP86840.1 - 3.8e-18 66.1 0.0 9.8e-18 64.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 GAP86840.1 - 0.00022 21.0 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP86840.1 - 0.00086 19.3 0.8 0.0022 18.0 0.6 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 GAP86840.1 - 0.049 14.0 0.0 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein BLM10_mid PF16507.5 GAP86841.1 - 5.3e-202 672.1 0.0 7.9e-202 671.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 GAP86841.1 - 2.1e-28 98.1 0.0 7.7e-28 96.2 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 GAP86841.1 - 4e-20 71.9 0.0 9.6e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal IFRD PF05004.13 GAP86841.1 - 0.12 11.5 0.0 17 4.4 0.0 2.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) MFS_1 PF07690.16 GAP86843.1 - 1.9e-07 30.4 31.6 1e-06 27.9 31.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 GAP86844.1 - 6.5e-11 41.8 10.3 7.9e-11 41.5 10.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP86844.1 - 0.00025 20.1 0.0 0.00026 20.0 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 GAP86844.1 - 0.0065 15.8 8.2 0.0084 15.4 8.2 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_5 PF05631.14 GAP86844.1 - 0.0096 14.9 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_2 PF13347.6 GAP86844.1 - 0.05 12.1 3.5 0.071 11.7 3.5 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein EKLF_TAD1 PF16832.5 GAP86844.1 - 0.74 9.7 3.7 1.3 8.9 3.7 1.3 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Mannosyl_trans2 PF04188.13 GAP86846.1 - 7.7e-55 187.0 6.9 1.3e-54 186.3 6.9 1.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) Nuc_sug_transp PF04142.15 GAP86848.1 - 8.8e-86 287.9 12.7 2.1e-85 286.7 12.7 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 GAP86848.1 - 2.9e-06 26.7 13.7 1.4e-05 24.4 13.7 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAP86848.1 - 7.6e-05 22.9 32.4 0.00016 21.9 7.2 2.4 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAP86848.1 - 0.016 14.6 17.4 0.47 9.8 5.4 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family Ni_hydr_CYTB PF01292.20 GAP86848.1 - 0.13 11.9 0.1 0.13 11.9 0.1 2.4 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 ETRAMP PF09716.10 GAP86848.1 - 0.28 11.3 2.1 31 4.7 0.0 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DMT_6 PF04342.12 GAP86848.1 - 8.2 6.7 9.7 7.7 6.8 0.2 2.6 3 0 0 3 3 3 0 Putative member of DMT superfamily (DUF486) Sec63 PF02889.16 GAP86849.1 - 1.5e-31 109.5 0.0 7.7e-31 107.2 0.0 1.9 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.29 GAP86849.1 - 4.3e-25 88.5 0.1 8.2e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 GAP86849.1 - 1.4e-11 44.7 0.0 2.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAP86849.1 - 6.7e-09 36.1 0.0 2e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 GAP86849.1 - 2e-06 28.2 0.1 0.002 18.4 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAP86849.1 - 0.0041 16.9 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAP86849.1 - 0.039 14.2 1.6 0.084 13.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 GAP86849.1 - 0.055 12.5 0.0 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein UvrD-helicase PF00580.21 GAP86849.1 - 0.099 12.1 0.1 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DNA_pol_lambd_f PF10391.9 GAP86849.1 - 0.2 11.5 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Oxidored_FMN PF00724.20 GAP86850.1 - 1.8e-41 142.6 0.0 2.7e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family 2OG-FeII_Oxy_3 PF13640.6 GAP86851.1 - 7.4e-09 36.4 0.0 1.5e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aha1_N PF09229.11 GAP86852.1 - 7.9e-39 133.0 0.3 1.2e-38 132.4 0.3 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 GAP86852.1 - 1.5e-19 70.5 0.6 3.1e-19 69.4 0.6 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein FSIP2 PF15783.5 GAP86852.1 - 0.023 12.7 0.2 0.032 12.2 0.2 1.1 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 Sugar_tr PF00083.24 GAP86853.1 - 1.6e-78 264.6 19.1 2.1e-78 264.2 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP86853.1 - 9.9e-36 123.4 43.9 4.8e-31 108.0 24.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAP86853.1 - 0.00016 20.2 3.2 0.00032 19.3 3.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 GAP86853.1 - 0.0042 15.9 14.7 0.023 13.5 4.3 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter Glyco_hydro_2_C PF02836.17 GAP86854.1 - 1.5e-98 329.7 0.0 2.1e-98 329.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 GAP86854.1 - 3.3e-60 203.7 0.0 5.7e-60 202.9 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 GAP86854.1 - 1.1e-38 132.8 0.3 2.4e-38 131.7 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 GAP86854.1 - 2.6e-18 66.3 0.0 6.7e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 GAP86854.1 - 7.9e-09 36.2 0.1 8.3e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 GAP86854.1 - 0.067 13.8 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Pec_lyase_C PF00544.19 GAP86855.1 - 1.4e-43 148.9 10.0 2e-43 148.5 10.0 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GAP86855.1 - 2.7e-06 27.3 16.3 0.00013 21.8 14.1 2.2 1 1 1 2 2 2 2 Right handed beta helix region Alpha_kinase PF02816.18 GAP86856.1 - 2.3e-49 168.1 0.0 3.3e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 GAP86856.1 - 2.9e-13 50.4 0.0 8.8e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain RNaseH_pPIWI_RE PF13032.6 GAP86857.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 RNaseH domain of pPIWI_RE APH PF01636.23 GAP86859.1 - 8.7e-08 32.4 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GAP86859.1 - 0.29 9.9 0.0 0.41 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ank_2 PF12796.7 GAP86860.1 - 4.3e-18 65.7 5.0 0.0027 18.3 0.1 9.6 7 3 3 11 11 11 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP86860.1 - 1.9e-08 33.9 6.1 48 5.0 0.0 11.4 13 0 0 13 13 13 0 Ankyrin repeat Ank_4 PF13637.6 GAP86860.1 - 0.00011 22.6 6.9 7.4 7.3 0.1 8.1 11 1 1 12 12 12 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP86860.1 - 0.00096 19.4 1.0 35 4.9 0.0 6.7 8 0 0 8 8 8 0 Ankyrin repeats (many copies) CNOT1_HEAT PF16418.5 GAP86860.1 - 0.0099 16.0 0.1 0.037 14.1 0.1 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat AbiEi_3 PF11459.8 GAP86860.1 - 0.014 15.1 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Peptidase_M4_C PF02868.15 GAP86861.1 - 9e-48 162.3 0.0 1.9e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 GAP86861.1 - 8.2e-27 94.5 3.0 1.4e-26 93.8 3.0 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 GAP86861.1 - 1.1e-19 69.8 0.5 1.4e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 Protealysin propeptide MFS_1 PF07690.16 GAP86862.1 - 5.6e-07 28.8 26.7 2.8e-06 26.5 26.7 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP86862.1 - 3e-06 25.9 0.5 4.4e-06 25.4 0.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AAA_12 PF13087.6 GAP86863.1 - 5.5e-39 133.9 0.0 9.8e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAP86863.1 - 1.3e-22 80.9 0.2 2.9e-22 79.7 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAP86863.1 - 6e-09 36.4 0.0 7.8e-08 32.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GAP86863.1 - 1.6e-06 27.9 0.0 0.0024 17.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain zf-CCCH_4 PF18044.1 GAP86863.1 - 9.2e-06 25.3 6.4 2.1e-05 24.2 6.4 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger DUF2075 PF09848.9 GAP86863.1 - 1.1e-05 24.9 0.1 0.062 12.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf-CCCH PF00642.24 GAP86863.1 - 0.0013 18.6 4.6 0.0034 17.3 4.6 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) XdhC_C PF13478.6 GAP86863.1 - 0.0016 18.9 0.0 3.1 8.3 0.0 3.2 3 0 0 3 3 3 2 XdhC Rossmann domain Viral_helicase1 PF01443.18 GAP86863.1 - 0.0019 18.0 0.5 0.14 11.9 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Torus PF16131.5 GAP86863.1 - 0.0024 18.5 0.8 0.0066 17.1 0.8 1.6 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 GAP86863.1 - 0.0027 17.7 7.5 0.0064 16.5 7.5 1.7 1 0 0 1 1 1 1 Zinc finger domain AAA_16 PF13191.6 GAP86863.1 - 0.14 12.5 1.6 0.28 11.5 0.2 2.2 2 0 0 2 2 2 0 AAA ATPase domain zf-CCCH_2 PF14608.6 GAP86863.1 - 2.2 8.9 4.7 6.6 7.4 4.7 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Spc24 PF08286.11 GAP86865.1 - 4.1e-36 123.4 0.0 2.6e-33 114.4 0.0 2.2 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 L31 PF09784.9 GAP86865.1 - 0.029 14.8 0.3 0.046 14.1 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF3584 PF12128.8 GAP86865.1 - 0.11 10.0 8.8 0.14 9.6 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAUS-augmin3 PF14932.6 GAP86865.1 - 0.23 11.0 3.8 0.3 10.6 3.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 GAP86865.1 - 0.25 10.6 4.1 0.33 10.3 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 GAP86865.1 - 2.4 8.2 10.9 5.3 7.1 10.9 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 GAP86865.1 - 3.7 7.9 7.9 9.1 6.6 0.5 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Fis1_TPR_C PF14853.6 GAP86866.1 - 1.8e-26 91.9 1.8 3.3e-26 91.1 1.8 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 GAP86866.1 - 6.9e-17 60.8 0.1 1.2e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 GAP86866.1 - 0.0052 16.8 2.3 0.0098 15.9 2.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Podoplanin PF05808.11 GAP86866.1 - 0.5 10.5 1.6 0.94 9.6 1.6 1.4 1 0 0 1 1 1 0 Podoplanin zf-RING_2 PF13639.6 GAP86867.1 - 2.1e-14 53.5 6.2 2.1e-14 53.5 6.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 GAP86867.1 - 3.1e-11 42.8 3.4 3.1e-11 42.8 3.4 2.7 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 GAP86867.1 - 7.4e-09 35.3 10.6 2.9e-08 33.5 1.9 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP86867.1 - 3.4e-08 33.2 5.9 3.4e-08 33.2 5.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAP86867.1 - 5.8e-08 32.9 5.3 5.8e-08 32.9 5.3 2.5 3 1 0 3 3 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 GAP86867.1 - 2e-06 27.6 4.1 2e-06 27.6 4.1 1.8 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAP86867.1 - 1.2e-05 25.2 3.3 1.2e-05 25.2 3.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAP86867.1 - 2.9e-05 23.8 5.0 2.9e-05 23.8 5.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP86867.1 - 0.00021 21.3 3.2 0.00021 21.3 3.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAP86867.1 - 0.00041 20.3 1.9 0.00041 20.3 1.9 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 GAP86867.1 - 0.02 14.8 4.5 5 7.1 0.9 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 GAP86867.1 - 0.24 11.1 13.9 0.025 14.2 5.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 GAP86867.1 - 4.4 7.3 15.8 0.69 9.9 5.2 2.8 2 1 0 2 2 2 0 PHD-finger HypA PF01155.19 GAP86867.1 - 6.8 6.7 7.5 0.55 10.3 1.1 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PBP1_TM PF14812.6 GAP86868.1 - 0.032 14.6 6.1 3.5 8.1 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.22 GAP86868.1 - 0.85 8.8 1.6 1.2 8.3 1.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Fungal_trans PF04082.18 GAP86869.1 - 2.8e-24 85.6 0.9 4.4e-24 84.9 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP86869.1 - 6.2e-08 32.6 9.9 1.3e-07 31.6 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med9 PF07544.13 GAP86870.1 - 0.15 12.2 0.4 5.4 7.2 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Pyridox_oxase_2 PF12766.7 GAP86871.1 - 1.9e-16 60.5 0.0 5.4e-14 52.6 0.0 3.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.17 GAP86872.1 - 6.2e-113 375.5 0.2 6e-83 277.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 GAP86872.1 - 8.6e-46 154.9 0.0 1.9e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 GAP86872.1 - 1.5e-45 154.8 0.0 3.5e-45 153.6 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 GAP86872.1 - 1e-43 149.3 0.0 3.2e-43 147.7 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 GAP86872.1 - 2e-38 131.5 0.0 4.7e-38 130.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 GAP86872.1 - 6.8e-30 104.2 0.0 1.6e-29 103.0 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 GAP86872.1 - 3.4e-21 75.2 0.0 1.8e-20 72.9 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 GAP86872.1 - 1.3e-16 60.6 0.2 2.4e-09 37.0 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 GAP86872.1 - 1.4e-15 57.4 1.1 4.3e-07 29.7 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 GAP86872.1 - 2.7e-10 40.1 0.0 4.8e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon DJ-1_PfpI PF01965.24 GAP86872.1 - 5e-06 26.4 0.0 0.0061 16.4 0.0 3.9 3 0 0 3 3 3 1 DJ-1/PfpI family ATP-grasp_3 PF02655.14 GAP86872.1 - 5.2e-06 26.6 0.7 0.014 15.4 0.1 2.9 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.13 GAP86872.1 - 5e-05 23.2 0.3 0.0029 17.4 0.3 2.5 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 GAP86872.1 - 0.02 14.7 0.2 1.5 8.6 0.0 2.9 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.18 GAP86872.1 - 0.13 12.5 0.1 0.75 10.1 0.0 2.4 3 0 0 3 3 1 0 TrkA-N domain Nipped-B_C PF12830.7 GAP86875.1 - 4.1e-47 160.6 2.2 1.2e-44 152.5 2.3 3.5 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 GAP86875.1 - 4.6e-08 33.2 2.5 4.8e-07 30.0 0.2 3.5 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 GAP86875.1 - 3.1e-05 24.1 0.2 0.044 13.8 0.1 3.0 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAP86875.1 - 9e-05 22.4 1.9 0.013 15.7 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat Adaptin_N PF01602.20 GAP86875.1 - 0.00014 20.6 0.0 0.056 12.0 0.0 3.3 2 1 1 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.7 GAP86875.1 - 0.0002 20.7 0.1 0.35 10.0 0.0 2.7 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain DUF4942 PF13708.6 GAP86875.1 - 0.092 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) TFIIS_C PF01096.18 GAP86876.1 - 1.1e-14 54.0 0.6 1.1e-14 54.0 0.6 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 GAP86876.1 - 0.00015 21.5 8.5 0.00016 21.5 3.7 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit HEAT_2 PF13646.6 GAP86877.1 - 2.8e-25 88.5 5.8 1.9e-11 44.2 0.9 3.6 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 GAP86877.1 - 2.2e-18 65.0 4.3 0.0053 17.3 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 GAP86877.1 - 1.7e-06 27.8 3.5 3.6 8.1 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 GAP86877.1 - 0.0022 18.5 6.2 4.7 7.8 0.1 5.3 4 1 2 6 6 6 2 HEAT-like repeat PNP_phzG_C PF10590.9 GAP86878.1 - 1.5e-20 73.0 3.2 2.4e-20 72.3 0.9 2.5 3 0 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 GAP86878.1 - 7e-20 71.0 0.0 1.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 GAP86878.1 - 0.064 13.9 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase adh_short_C2 PF13561.6 GAP86879.1 - 1.8e-54 184.8 0.3 2.7e-54 184.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP86879.1 - 6.9e-48 162.7 2.7 8.6e-48 162.4 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP86879.1 - 5.6e-13 49.2 0.3 7.2e-13 48.8 0.3 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 GAP86879.1 - 0.0018 18.3 1.4 0.45 10.5 1.4 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 GAP86879.1 - 0.035 13.4 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1372 PF07116.11 GAP86879.1 - 0.054 13.7 0.3 0.17 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1372) 2-Hacid_dh_C PF02826.19 GAP86879.1 - 0.073 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 GAP86879.1 - 0.13 11.4 0.4 2.9 7.0 0.1 2.5 2 1 1 3 3 3 0 Male sterility protein MccV PF17508.2 GAP86879.1 - 0.24 11.9 1.3 28 5.3 0.2 2.6 2 0 0 2 2 2 0 Microcin V bacteriocin AAA PF00004.29 GAP86880.1 - 1.1e-15 58.2 0.0 2.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP86880.1 - 0.0018 18.7 0.2 0.0055 17.1 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain Zot PF05707.12 GAP86880.1 - 0.0029 17.3 0.2 0.096 12.3 0.2 2.3 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) Torsin PF06309.11 GAP86880.1 - 0.036 14.2 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.6 GAP86880.1 - 0.04 14.2 1.0 0.32 11.3 0.2 2.5 2 1 1 3 3 3 0 AAA domain DUF2075 PF09848.9 GAP86880.1 - 0.066 12.4 0.3 0.17 11.1 0.3 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 GAP86880.1 - 0.067 12.5 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 GAP86880.1 - 0.095 12.9 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAP86880.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Bactofilin PF04519.13 GAP86880.1 - 0.17 12.2 2.8 0.35 11.2 2.8 1.4 1 0 0 1 1 1 0 Polymer-forming cytoskeletal DUF1308 PF07000.11 GAP86881.1 - 6.4e-07 29.4 0.0 6.6e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 GAP86881.1 - 0.083 12.2 0.0 8.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5614) Cutinase PF01083.22 GAP86882.1 - 3.5e-44 150.9 2.0 4.4e-44 150.6 2.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAP86882.1 - 0.0018 17.9 0.1 0.0032 17.0 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain Glyco_hydro_18 PF00704.28 GAP86883.1 - 1.5e-21 77.4 0.0 4.9e-21 75.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Aldo_ket_red PF00248.21 GAP86884.1 - 5.4e-37 127.6 0.0 1.2e-36 126.5 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 GAP86887.1 - 2e-56 191.7 0.0 2.6e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 GAP86888.1 - 2.7e-23 82.5 0.1 3.5e-23 82.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP86888.1 - 3.7e-18 65.9 0.1 4.6e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP86888.1 - 0.0011 18.9 0.1 0.0017 18.3 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAP86888.1 - 0.073 12.4 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FAD_binding_4 PF01565.23 GAP86889.1 - 9.6e-23 80.5 4.0 2.7e-22 79.0 4.0 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP86889.1 - 1.1e-08 35.0 0.3 2.4e-08 33.9 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_6 PF12697.7 GAP86890.1 - 1.9e-11 45.0 0.9 2.5e-11 44.6 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP86890.1 - 3e-10 39.8 0.0 9.1e-10 38.2 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP86890.1 - 4.4e-08 33.1 0.0 2.4e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 GAP86890.1 - 2.1e-07 30.8 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 GAP86890.1 - 9.1e-07 28.6 0.0 0.00022 20.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 GAP86890.1 - 1.1e-05 24.3 0.0 6.6e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF1100 PF06500.11 GAP86890.1 - 9.3e-05 21.4 0.0 0.001 18.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.11 GAP86890.1 - 0.00016 21.6 0.0 0.0017 18.4 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 GAP86890.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 GAP86890.1 - 0.17 11.5 0.0 0.47 10.1 0.0 1.8 2 1 0 2 2 2 0 Putative esterase ketoacyl-synt PF00109.26 GAP86891.1 - 3.1e-66 223.5 0.1 5.8e-66 222.6 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 GAP86891.1 - 2.5e-56 191.1 0.0 3.7e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 GAP86891.1 - 7.8e-55 185.6 0.0 1.8e-54 184.4 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 GAP86891.1 - 2.1e-51 175.3 0.0 3.6e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP86891.1 - 2.9e-34 117.6 2.1 8.4e-34 116.1 2.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAP86891.1 - 1.4e-20 73.8 0.0 3.5e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 GAP86891.1 - 6.4e-17 62.9 0.0 3.3e-16 60.5 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAP86891.1 - 2.7e-16 59.7 0.0 1.4e-15 57.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 GAP86891.1 - 2.5e-06 27.7 0.1 6.5e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 GAP86891.1 - 1.9e-05 24.5 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_N PF08240.12 GAP86891.1 - 2.2e-05 24.3 0.0 6.1e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 GAP86891.1 - 0.0026 17.2 0.5 0.0098 15.4 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 GAP86891.1 - 0.055 12.8 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain HNH_2 PF13391.6 GAP86892.1 - 3.3e-11 43.1 0.2 1.3e-10 41.3 0.2 2.0 1 0 0 1 1 1 1 HNH endonuclease TRP PF06011.12 GAP86893.1 - 2.4e-146 487.8 27.8 3.1e-146 487.5 27.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 GAP86893.1 - 5.7e-38 130.4 0.1 9.9e-38 129.6 0.1 1.4 1 0 0 1 1 1 1 ML-like domain MFS_1 PF07690.16 GAP86894.1 - 1.5e-20 73.4 57.5 1.9e-20 73.1 57.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Inhibitor_I9 PF05922.16 GAP86895.1 - 9.9e-11 42.2 0.0 2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 GAP86895.1 - 6e-05 22.5 2.5 6.2e-05 22.4 1.0 1.7 2 0 0 2 2 2 1 Subtilase family Glyco_hydro_64 PF16483.5 GAP86896.1 - 3e-125 418.3 0.0 3.4e-125 418.2 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Evr1_Alr PF04777.13 GAP86897.1 - 2.7e-21 75.9 0.0 3.5e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Proteasome PF00227.26 GAP86898.1 - 7.1e-46 156.1 0.1 8.2e-46 155.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 GAP86899.1 - 3.8e-42 144.4 2.5 6.5e-25 88.4 0.1 2.7 2 0 0 2 2 2 2 Cyclin FMO-like PF00743.19 GAP86900.1 - 5.6e-20 71.3 0.0 6.6e-17 61.1 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAP86900.1 - 7.3e-14 51.7 0.0 2.2e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP86900.1 - 1.9e-12 47.1 0.0 1.2e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP86900.1 - 1.5e-09 37.9 0.1 2.1e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP86900.1 - 7e-09 35.7 0.0 0.0051 16.4 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAP86900.1 - 2.6e-08 34.0 0.2 1.2e-07 31.9 0.1 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAP86900.1 - 3.8e-05 23.0 0.2 0.0049 16.1 0.0 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 GAP86900.1 - 8.4e-05 21.4 0.0 0.027 13.2 0.1 2.5 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 GAP86900.1 - 0.00085 19.8 0.1 7.6 7.2 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP86900.1 - 0.0047 16.2 0.2 0.01 15.1 0.0 1.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 GAP86900.1 - 0.0084 15.4 0.1 0.059 12.6 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain MciZ PF13072.6 GAP86900.1 - 0.12 12.2 0.9 0.26 11.1 0.9 1.5 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ TFR_dimer PF04253.15 GAP86901.1 - 1.3e-22 80.2 0.0 2.1e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 GAP86901.1 - 1.1e-19 70.9 0.0 1.9e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAP86901.1 - 8.5e-09 35.3 2.5 9.8e-09 35.1 0.6 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 GAP86901.1 - 0.035 13.8 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Methyltransf_25 PF13649.6 GAP86902.1 - 1.2e-11 45.2 0.0 2.7e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP86902.1 - 5.7e-09 36.6 0.0 1.2e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP86902.1 - 2.2e-08 34.6 0.0 4.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP86902.1 - 2.6e-06 27.3 0.0 4.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP86902.1 - 6.2e-05 22.9 0.0 9.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 GAP86902.1 - 0.072 12.6 0.0 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase OTT_1508_deam PF14441.6 GAP86903.1 - 7.6e-07 29.0 0.3 2.9e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 OTT_1508-like deaminase DUF3127 PF11325.8 GAP86903.1 - 0.062 13.5 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) HET PF06985.11 GAP86905.1 - 2.7e-31 108.9 0.1 4.8e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 GAP86906.1 - 3.5e-29 102.1 0.1 7.1e-29 101.0 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RPW8 PF05659.11 GAP86907.1 - 0.0022 17.7 0.4 0.0022 17.7 0.4 2.3 2 1 0 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF948 PF06103.11 GAP86907.1 - 0.032 14.5 1.0 2.6 8.4 0.1 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Rx_N PF18052.1 GAP86907.1 - 0.06 13.6 0.7 0.43 10.9 0.2 2.7 2 1 0 2 2 2 0 Rx N-terminal domain Ribosomal_L12 PF00542.19 GAP86907.1 - 0.56 10.6 5.6 0.67 10.4 0.2 3.4 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain RNase_H PF00075.24 GAP86908.1 - 3.1e-18 66.3 0.0 6.1e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-MYND PF01753.18 GAP86908.1 - 1.3e-07 31.5 10.0 2.8e-07 30.5 10.0 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 GAP86908.1 - 0.17 12.0 8.3 0.29 11.3 6.1 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 HET PF06985.11 GAP86909.1 - 1.9e-25 89.9 0.0 4.1e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 GAP86910.1 - 1.6e-09 38.1 0.1 3e-08 33.9 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP86910.1 - 0.00083 19.0 0.0 0.0022 17.6 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 GAP86910.1 - 0.0065 15.7 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.11 GAP86910.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 GAP86911.1 - 2e-15 56.9 0.0 2.3e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP86911.1 - 1.3e-05 24.6 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP86911.1 - 0.00066 19.7 0.1 0.044 13.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAP86911.1 - 0.002 16.9 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Methyltransf_12 PF08242.12 GAP86912.1 - 0.092 13.5 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAP86912.1 - 0.12 13.1 0.0 0.26 12.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PT PF04886.12 GAP86913.1 - 0.00019 20.9 22.0 0.0068 15.9 12.1 2.8 2 0 0 2 2 2 2 PT repeat Glyco_trans_2_3 PF13632.6 GAP86913.1 - 0.0025 17.8 0.4 0.0076 16.2 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF913 PF06025.12 GAP86913.1 - 0.3 10.0 1.7 0.47 9.4 1.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 GAP86913.1 - 1.9 6.7 10.2 2.6 6.2 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 GAP86914.1 - 5.1e-35 121.0 49.5 8.2e-34 117.1 48.8 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP86914.1 - 2.8e-14 52.9 14.6 2.8e-14 52.9 14.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAP86914.1 - 7.1e-13 47.8 21.0 1e-12 47.3 21.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 GAP86915.1 - 2.3e-60 204.7 0.0 2.8e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos PF00149.28 GAP86918.1 - 1.2e-31 110.8 0.1 2e-22 80.7 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAP86918.1 - 0.071 13.6 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 GAP86919.1 - 0.00014 21.9 0.8 0.00021 21.3 0.8 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 BDV_P10 PF06515.11 GAP86919.1 - 1.9 8.6 7.8 0.17 11.9 2.4 1.9 2 0 0 2 2 2 0 Borna disease virus P10 protein GATA PF00320.27 GAP86920.1 - 1.8e-14 53.0 2.5 3.2e-14 52.2 2.5 1.4 1 0 0 1 1 1 1 GATA zinc finger Wtap PF17098.5 GAP86920.1 - 0.0019 18.1 3.9 0.0019 18.1 3.9 2.4 1 1 1 2 2 2 1 WTAP/Mum2p family MMADHC PF10229.9 GAP86920.1 - 0.004 16.9 0.8 0.0062 16.3 0.4 1.5 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein APG6_N PF17675.1 GAP86920.1 - 0.017 15.7 18.2 0.038 14.5 18.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF2802 PF10975.8 GAP86920.1 - 0.048 13.8 9.1 0.2 11.8 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) FIN1 PF17300.2 GAP86920.1 - 0.068 12.7 7.4 0.14 11.6 7.4 1.5 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Cnn_1N PF07989.11 GAP86920.1 - 0.088 13.0 13.5 1 9.5 0.5 3.2 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 TF_Zn_Ribbon PF08271.12 GAP86920.1 - 0.11 12.0 0.5 0.21 11.2 0.5 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding XhlA PF10779.9 GAP86920.1 - 0.12 12.6 7.4 0.14 12.4 3.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA PI3K_P85_iSH2 PF16454.5 GAP86920.1 - 0.15 11.6 15.1 0.25 10.9 15.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fib_alpha PF08702.10 GAP86920.1 - 0.17 12.1 7.0 0.32 11.2 7.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 GAP86920.1 - 0.17 11.4 6.8 0.47 10.0 6.8 1.8 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 GAP86920.1 - 0.23 10.0 8.0 0.32 9.6 8.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Golgin_A5 PF09787.9 GAP86920.1 - 0.49 9.8 18.4 0.81 9.1 18.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fungal_trans_2 PF11951.8 GAP86920.1 - 0.75 8.5 4.1 1.1 7.9 4.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain CENP-F_leu_zip PF10473.9 GAP86920.1 - 0.78 9.8 18.6 6 6.9 1.1 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CHDCT2 PF08074.11 GAP86920.1 - 0.81 9.8 5.7 1.5 9.0 5.7 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Spc7 PF08317.11 GAP86920.1 - 1 8.1 18.6 1.8 7.4 18.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein PIN_8 PF18476.1 GAP86920.1 - 1.5 8.7 7.8 2.2 8.1 7.8 1.2 1 0 0 1 1 1 0 PIN like domain Csm1_N PF18504.1 GAP86920.1 - 2.7 8.4 11.9 1.2 9.6 4.4 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain TMPIT PF07851.13 GAP86920.1 - 3.7 6.7 6.8 5.6 6.1 6.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein GAS PF13851.6 GAP86920.1 - 3.9 6.8 19.7 0.87 8.9 12.9 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HAUS6_N PF14661.6 GAP86920.1 - 4.4 6.8 10.8 7.5 6.1 10.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Atg14 PF10186.9 GAP86920.1 - 5 6.1 16.3 9.7 5.2 16.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fmp27_WPPW PF10359.9 GAP86920.1 - 5.4 5.8 12.3 8.1 5.2 12.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain SpecificRecomb PF10136.9 GAP86920.1 - 6 5.0 5.9 9.3 4.4 5.9 1.2 1 0 0 1 1 1 0 Site-specific recombinase AAA_23 PF13476.6 GAP86920.1 - 8.5 6.8 8.8 14 6.1 8.8 1.2 1 0 0 1 1 1 0 AAA domain KH_8 PF17903.1 GAP86921.1 - 8e-13 48.3 0.0 5.5e-10 39.2 0.0 2.8 2 0 0 2 2 2 2 Krr1 KH1 domain DUF383 PF04063.14 GAP86922.1 - 3.3e-60 203.0 0.3 1.1e-59 201.3 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 GAP86922.1 - 4.2e-21 74.5 3.1 4.2e-21 74.5 3.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Sugar_tr PF00083.24 GAP86925.1 - 1.2e-50 172.8 16.3 1.4e-50 172.5 16.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP86925.1 - 8.2e-15 54.6 33.4 1e-14 54.2 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FMN_dh PF01070.18 GAP86926.1 - 1.2e-119 399.4 0.1 1.4e-119 399.2 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAP86926.1 - 3.6e-23 81.5 0.1 7.2e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 GAP86926.1 - 9.1e-07 28.3 0.1 1.5e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAP86926.1 - 0.00085 18.4 1.5 0.0015 17.6 0.2 2.0 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 GAP86926.1 - 0.0012 18.3 1.0 0.0026 17.2 0.3 1.8 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 GAP86926.1 - 0.045 13.2 0.5 0.76 9.2 0.1 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 GAP86926.1 - 0.12 11.7 0.2 6 6.1 0.1 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ras PF00071.22 GAP86927.1 - 7e-39 133.0 0.0 1e-36 126.0 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 GAP86927.1 - 5.9e-31 107.2 0.0 8.9e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP86927.1 - 1.5e-09 37.6 0.0 2.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAP86927.1 - 0.00038 20.5 0.0 0.00061 19.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAP86927.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SOG2 PF10428.9 GAP86927.1 - 0.021 14.0 2.1 0.026 13.7 2.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein AAA_16 PF13191.6 GAP86927.1 - 0.058 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 GAP86927.1 - 0.11 11.3 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 GAP86927.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAP86927.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Menin PF05053.13 GAP86927.1 - 0.73 8.1 5.1 1.1 7.6 5.1 1.1 1 0 0 1 1 1 0 Menin GRP PF07172.11 GAP86927.1 - 6.6 7.5 13.8 2.4 8.9 5.8 2.3 2 0 0 2 2 2 0 Glycine rich protein family AAA PF00004.29 GAP86928.1 - 1.9e-50 170.7 0.0 2.2e-40 138.2 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAP86928.1 - 6.3e-12 45.1 0.5 2.5e-07 30.4 0.3 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 GAP86928.1 - 3.5e-07 30.3 0.1 0.00039 20.4 0.0 3.3 3 2 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAP86928.1 - 1e-05 26.0 0.0 0.46 10.8 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 GAP86928.1 - 2.8e-05 24.1 0.0 0.033 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAP86928.1 - 4.4e-05 23.2 0.6 0.53 9.8 0.0 3.8 2 2 2 4 4 4 1 AAA domain RuvB_N PF05496.12 GAP86928.1 - 0.00014 21.6 0.0 0.0084 15.9 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAP86928.1 - 0.00037 20.7 0.0 0.81 9.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain CDC48_N PF02359.18 GAP86928.1 - 0.00043 20.4 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_28 PF13521.6 GAP86928.1 - 0.00057 20.2 0.1 0.24 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 GAP86928.1 - 0.0025 17.7 0.6 0.11 12.4 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 GAP86928.1 - 0.0029 17.9 1.7 4.8 7.5 0.0 3.9 3 2 2 5 5 5 1 AAA domain ATPase_2 PF01637.18 GAP86928.1 - 0.0053 16.7 0.1 2.1 8.2 0.0 3.2 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 GAP86928.1 - 0.0056 17.0 0.0 2.4 8.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 GAP86928.1 - 0.0062 15.9 0.2 0.36 10.2 0.1 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 GAP86928.1 - 0.015 14.7 1.2 1.9 7.8 0.5 3.0 2 1 0 2 2 2 0 KaiC TIP49 PF06068.13 GAP86928.1 - 0.019 14.2 0.1 0.051 12.8 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Rad17 PF03215.15 GAP86928.1 - 0.031 14.2 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_2 PF07724.14 GAP86928.1 - 0.065 13.3 0.1 1.6 8.8 0.0 2.7 2 2 0 2 2 2 0 AAA domain (Cdc48 subfamily) DAP3 PF10236.9 GAP86928.1 - 0.089 11.9 0.2 1.6 7.9 0.1 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 GAP86928.1 - 0.13 11.8 0.1 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region CDC45 PF02724.14 GAP86928.1 - 0.14 10.5 0.0 0.22 9.8 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TsaE PF02367.17 GAP86928.1 - 0.14 12.1 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_6 PF17866.1 GAP86928.1 - 2.2 8.5 6.9 0.94 9.7 0.1 3.4 4 0 0 4 4 4 0 AAA lid domain NHase_beta PF02211.15 GAP86929.1 - 0.13 12.3 1.6 1.5 8.7 0.1 2.3 1 1 1 2 2 2 0 Nitrile hydratase beta subunit IATP PF04568.12 GAP86929.1 - 2.2 8.8 5.6 0.6 10.6 2.0 1.9 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Ras PF00071.22 GAP86930.1 - 1.7e-64 216.3 0.0 2e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP86930.1 - 8.1e-34 116.4 0.1 1.1e-33 115.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP86930.1 - 2.8e-13 49.7 0.0 3.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAP86930.1 - 1.9e-05 24.3 0.0 4.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAP86930.1 - 0.0003 20.2 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAP86930.1 - 0.0034 17.3 0.2 2.6 7.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAP86930.1 - 0.0036 17.4 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAP86930.1 - 0.01 15.3 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.29 GAP86930.1 - 0.033 14.6 0.0 9.1 6.7 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 GAP86930.1 - 0.043 13.3 0.0 0.19 11.2 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 GAP86930.1 - 0.15 12.3 0.1 0.47 10.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF1241 PF06840.11 GAP86931.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Zn_clus PF00172.18 GAP86932.1 - 2.1e-05 24.5 13.1 4.8e-05 23.4 13.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec7 PF01369.20 GAP86933.1 - 1.4e-71 240.0 0.4 5.6e-71 238.0 0.1 2.3 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 GAP86933.1 - 1.3e-38 132.4 1.6 1.3e-38 132.4 1.6 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 GAP86933.1 - 4.8e-34 116.1 12.1 6.8e-32 109.2 0.0 6.2 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) DCB PF16213.5 GAP86933.1 - 2e-22 79.7 1.6 1.8e-19 70.1 0.2 3.6 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 2-oxoacid_dh PF00198.23 GAP86934.1 - 2.7e-78 262.6 0.2 3.5e-78 262.2 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAP86934.1 - 9.8e-19 67.0 0.9 2.2e-18 65.8 0.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 GAP86934.1 - 5.3e-12 45.9 0.7 5.3e-12 45.9 0.7 3.1 3 0 0 3 3 3 1 e3 binding domain DUF3614 PF12267.8 GAP86934.1 - 0.0061 17.1 0.8 0.013 16.0 0.3 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3614) Calycin_like PF13944.6 GAP86934.1 - 0.044 14.1 1.8 0.2 12.0 0.0 2.5 2 1 0 3 3 3 0 Calycin-like beta-barrel domain DUF2263 PF10021.9 GAP86935.1 - 7.8e-17 62.0 0.0 2.1e-16 60.6 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) baeRF_family10 PF18854.1 GAP86935.1 - 0.018 15.3 2.1 0.018 15.3 2.1 3.1 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 10 Fungal_trans PF04082.18 GAP86936.1 - 8.1e-10 38.2 0.0 3.1e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP86936.1 - 2e-07 31.0 9.2 3.9e-07 30.1 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferritin PF00210.24 GAP86936.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain DIOX_N PF14226.6 GAP86937.1 - 4.8e-12 46.7 0.0 8.2e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP86937.1 - 3.2e-08 34.0 0.0 5.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ferritin_2 PF13668.6 GAP86938.1 - 3.7e-08 33.6 0.0 5.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain PXB PF12828.7 GAP86938.1 - 0.039 13.9 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 PX-associated ketoacyl-synt PF00109.26 GAP86939.1 - 5.5e-65 219.4 0.0 1.1e-64 218.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP86939.1 - 3.4e-53 180.2 0.1 7.9e-53 179.0 0.1 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 GAP86939.1 - 1.9e-47 162.3 0.0 3.2e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAP86939.1 - 2.6e-40 138.5 0.1 4.2e-40 137.9 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAP86939.1 - 4.2e-37 126.8 0.1 1.6e-36 124.9 0.0 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 GAP86939.1 - 5.6e-18 66.3 0.0 7.1e-17 62.7 0.0 2.8 3 0 0 3 3 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 GAP86939.1 - 6.8e-17 61.9 0.3 2.2e-10 40.9 0.0 2.8 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 GAP86939.1 - 1.1e-16 61.4 0.0 3.1e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 GAP86939.1 - 5e-12 45.9 0.0 3.5e-11 43.2 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 GAP86939.1 - 4.3e-10 40.2 0.0 1.5e-09 38.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP86939.1 - 2.8e-09 36.9 0.0 7.6e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP86939.1 - 4e-09 37.0 0.0 1.3e-08 35.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP86939.1 - 9.9e-08 32.0 0.0 3e-07 30.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 GAP86939.1 - 1.2e-07 32.0 0.0 4.1e-07 30.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 GAP86939.1 - 9.5e-07 28.5 0.0 2.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Ubie_methyltran PF01209.18 GAP86939.1 - 1.3e-06 28.0 0.0 2.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 GAP86939.1 - 0.00097 18.6 0.8 0.0024 17.3 0.3 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 GAP86939.1 - 0.016 15.0 0.5 0.049 13.5 0.5 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAS PF03059.16 GAP86939.1 - 0.048 13.0 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Nicotianamine synthase protein Methyltransf_2 PF00891.18 GAP86939.1 - 0.09 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 GAP86939.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase FSH1 PF03959.13 GAP86940.1 - 9.6e-26 90.8 0.0 3e-25 89.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) p450 PF00067.22 GAP86942.1 - 5.8e-66 223.1 0.0 7.4e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tautomerase_2 PF14552.6 GAP86942.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme Ank_2 PF12796.7 GAP86943.1 - 2.8e-05 24.6 0.0 0.0067 17.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP86943.1 - 0.00029 21.1 0.6 0.0036 17.7 0.2 3.0 3 1 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 GAP86943.1 - 0.00099 19.6 0.1 0.0037 17.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP86943.1 - 0.014 15.7 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 GAP86943.1 - 0.072 13.6 0.1 0.31 11.6 0.1 2.1 1 0 0 1 1 1 0 Ankyrin repeat Aminotran_5 PF00266.19 GAP86944.1 - 1.8e-25 89.7 0.0 1.9e-24 86.3 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAP86944.1 - 0.00028 20.2 0.0 0.00066 19.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_3 PF00933.21 GAP86945.1 - 2.6e-42 145.3 0.0 4.1e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 GAP86945.1 - 2.5e-40 138.6 1.6 1.8e-35 122.7 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 GAP86945.1 - 1.9e-25 88.8 0.0 3.5e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Rick_17kDa_Anti PF05433.15 GAP86947.1 - 9.2e-06 25.4 13.7 9.2e-06 25.4 13.7 3.4 3 1 0 3 3 3 1 Glycine zipper 2TM domain Whi5 PF08528.11 GAP86948.1 - 3.3e-09 36.1 0.0 5.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Whi5 like ZZ PF00569.17 GAP86950.1 - 2.4e-07 30.5 33.1 5.4e-05 22.9 7.0 2.5 2 1 0 2 2 2 2 Zinc finger, ZZ type HET PF06985.11 GAP86951.1 - 2.8e-31 108.8 0.1 4.4e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PRIMA1 PF16101.5 GAP86951.1 - 0.035 14.2 2.0 0.068 13.2 2.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 adh_short PF00106.25 GAP86952.1 - 6e-23 81.3 0.0 1.2e-21 77.1 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP86952.1 - 1e-17 64.5 0.0 6e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP86952.1 - 5.9e-07 29.6 0.1 8.5e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP86952.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAP86953.1 - 1.1e-31 110.0 0.0 1.6e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAP86953.1 - 1.1e-24 86.9 0.0 1.7e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAP86953.1 - 7.5e-10 38.7 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAP86953.1 - 0.0019 18.5 0.0 0.0049 17.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 GAP86953.1 - 0.011 14.9 0.4 0.12 11.4 0.1 2.5 3 0 0 3 3 3 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 GAP86953.1 - 0.047 14.1 0.0 0.35 11.3 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 GAP86953.1 - 0.051 13.5 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 KR domain GYF PF02213.16 GAP86954.1 - 6.6e-19 67.3 0.2 1.5e-18 66.1 0.2 1.7 1 0 0 1 1 1 1 GYF domain TPR_1 PF00515.28 GAP86955.1 - 1.6e-10 40.4 2.0 0.00048 19.8 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAP86955.1 - 2.3e-10 39.8 6.4 7.2e-05 22.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAP86955.1 - 4.8e-09 36.4 1.9 0.00014 22.1 0.0 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAP86955.1 - 3.5e-08 34.0 4.8 1.9e-07 31.6 0.9 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAP86955.1 - 2.1e-05 24.9 0.7 0.56 10.8 0.2 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAP86955.1 - 5.4e-05 23.3 0.8 0.00017 21.6 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP86955.1 - 0.0003 21.2 2.5 9.9 7.0 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAP86955.1 - 0.00062 19.8 0.2 1.5 9.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAP86955.1 - 0.0012 18.7 0.4 0.65 10.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAP86955.1 - 0.0036 18.0 16.8 0.011 16.4 0.1 5.7 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 GAP86955.1 - 0.0077 16.0 0.3 5 6.8 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain SHNi-TPR PF10516.9 GAP86955.1 - 0.03 13.8 0.0 0.084 12.3 0.0 1.8 1 0 0 1 1 1 0 SHNi-TPR TPR_11 PF13414.6 GAP86955.1 - 0.041 13.6 1.3 2.4 7.9 0.0 3.4 2 1 1 3 3 3 0 TPR repeat SNAP PF14938.6 GAP86955.1 - 0.21 11.0 2.1 0.29 10.5 0.1 2.2 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 GAP86955.1 - 0.89 9.5 10.0 2.1 8.3 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Sirohm_synth_C PF14823.6 GAP86957.1 - 2.6e-28 97.4 0.0 3.9e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 GAP86957.1 - 2e-26 92.4 0.0 2.8e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 GAP86957.1 - 1.7e-13 49.8 0.0 2.9e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Cytotoxic PF09000.10 GAP86957.1 - 0.1 13.0 0.1 0.79 10.1 0.0 2.1 2 0 0 2 2 2 0 Cytotoxic Pyr_redox_3 PF13738.6 GAP86957.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FYVE PF01363.21 GAP86958.1 - 5.1e-24 84.2 20.8 5.2e-17 61.7 5.6 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 GAP86958.1 - 2.2e-16 59.3 0.4 5.5e-16 58.0 0.4 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 GAP86958.1 - 0.00018 21.6 2.0 0.00018 21.6 2.0 3.8 4 1 1 5 5 5 1 AN1-like Zinc finger zf-Di19 PF05605.12 GAP86958.1 - 0.00055 20.2 7.7 0.013 15.8 0.1 2.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Seryl_tRNA_N PF02403.22 GAP86958.1 - 0.0092 16.2 0.5 0.0092 16.2 0.5 2.4 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Siva PF05458.12 GAP86958.1 - 0.034 13.8 4.8 0.075 12.7 0.0 3.1 3 0 0 3 3 3 0 Cd27 binding protein (Siva) ABC_tran_CTD PF16326.5 GAP86958.1 - 0.23 11.7 3.0 21 5.5 0.6 3.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain zf-C2H2_9 PF16293.5 GAP86958.1 - 0.24 11.3 2.2 15 5.5 0.0 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 GAP86958.1 - 0.61 10.5 4.0 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) C6_DPF PF10170.9 GAP86958.1 - 3.6 8.0 7.7 0.34 11.3 0.6 2.8 3 0 0 3 3 3 0 Cysteine-rich domain GFA PF04828.14 GAP86958.1 - 9.3 6.7 10.2 0.5 10.7 2.1 3.0 3 1 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme CENP-L PF13092.6 GAP86960.1 - 5e-48 163.4 0.0 5.1e-47 160.1 0.0 2.1 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 DUF1509 PF07420.11 GAP86960.1 - 2 7.3 6.7 3.6 6.5 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Ank_4 PF13637.6 GAP86961.1 - 2.2e-12 47.2 0.2 1.7e-07 31.7 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP86961.1 - 1.9e-10 41.2 0.8 0.00048 20.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAP86961.1 - 2.1e-09 37.4 1.6 0.025 15.0 0.5 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 GAP86961.1 - 1.8e-08 34.0 0.3 0.21 12.3 0.0 4.8 4 1 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 GAP86961.1 - 1.4e-05 24.9 0.3 6.3e-05 22.8 0.3 2.0 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.6 GAP86961.1 - 1.7e-05 25.0 0.6 0.027 14.8 0.4 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF2973 PF11189.8 GAP86961.1 - 0.0028 17.7 0.0 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2973) DUF3584 PF12128.8 GAP86961.1 - 0.01 13.4 2.6 0.017 12.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Med2 PF11214.8 GAP86961.1 - 0.15 12.2 2.8 0.36 11.0 2.8 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 Complex1_LYR PF05347.15 GAP86962.1 - 4.4e-06 26.6 0.7 8.1e-06 25.8 0.7 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAP86962.1 - 0.034 14.9 0.3 0.069 13.9 0.3 1.5 1 0 0 1 1 1 0 Complex1_LYR-like Acetyltransf_1 PF00583.25 GAP86963.1 - 2.2e-14 53.7 0.0 2.8e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP86963.1 - 1.7e-07 31.2 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP86963.1 - 2.1e-07 31.3 0.0 3.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP86963.1 - 5.8e-07 29.4 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAP86963.1 - 0.03 14.5 0.0 0.07 13.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAP86963.1 - 0.03 15.0 0.0 0.042 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAP86963.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ MFS_1 PF07690.16 GAP86967.1 - 4.1e-35 121.4 25.1 4.1e-35 121.4 25.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 GAP86967.1 - 8.8 6.4 12.4 4.1 7.5 0.2 3.4 3 1 0 3 3 3 0 Bacteriophage P21 holin S NAD_binding_10 PF13460.6 GAP86968.1 - 0.0015 18.4 0.2 0.0021 18.0 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAP86968.1 - 0.0092 15.2 0.0 0.15 11.2 0.1 2.1 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 GAP86968.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAP86968.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 GAP86969.1 - 0.0041 17.2 10.3 0.0075 16.4 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAP86970.1 - 1.8e-32 112.6 29.4 2.5e-32 112.2 29.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily NRBF2 PF08961.10 GAP86971.1 - 0.037 13.6 0.6 0.06 12.9 0.6 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Mito_fiss_reg PF05308.11 GAP86971.1 - 0.46 10.5 4.1 0.73 9.9 4.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CoA_trans PF01144.23 GAP86972.1 - 1.2e-58 198.1 0.5 3.1e-50 170.6 0.1 2.2 2 0 0 2 2 2 2 Coenzyme A transferase UDPG_MGDP_dh_N PF03721.14 GAP86973.1 - 6e-41 140.1 0.0 3.5e-30 105.0 0.0 2.3 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 GAP86973.1 - 1e-29 102.5 0.0 2.1e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 GAP86973.1 - 4.1e-19 68.9 0.0 1.3e-14 54.5 0.0 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain HET PF06985.11 GAP86975.1 - 1.3e-28 100.2 0.0 3.5e-27 95.5 0.0 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RTA1 PF04479.13 GAP86976.1 - 8e-53 179.1 10.0 8e-53 179.1 10.0 1.7 2 0 0 2 2 2 1 RTA1 like protein Herpes_UL87 PF03043.14 GAP86977.1 - 0.27 9.6 0.0 0.36 9.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Condensation PF00668.20 GAP86978.1 - 3.4e-48 164.5 0.0 6.7e-33 114.0 0.0 3.3 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 GAP86978.1 - 1.5e-14 54.1 0.0 4e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 GAP86978.1 - 0.013 14.1 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme AMP-binding PF00501.28 GAP86979.1 - 5e-75 252.7 0.0 8.2e-75 252.0 0.0 1.3 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 GAP86979.1 - 6.7e-11 42.4 0.2 8.2e-10 38.9 0.1 2.6 3 0 0 3 3 3 1 Phosphopantetheine attachment site Myb_DNA-bind_3 PF12776.7 GAP86980.1 - 1.8e-21 76.9 0.7 2.9e-21 76.2 0.7 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain BCS1_N PF08740.11 GAP86981.1 - 6.9e-28 97.9 0.7 6.9e-28 97.9 0.7 1.9 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 GAP86981.1 - 5.4e-16 59.2 0.0 1.5e-15 57.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 GAP86981.1 - 0.0058 16.4 1.2 5 6.8 1.7 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAP86981.1 - 0.0097 16.3 0.2 0.036 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GAP86981.1 - 0.025 14.5 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 GAP86981.1 - 0.057 13.0 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain U1snRNP70_N PF12220.8 GAP86981.1 - 0.22 12.2 3.8 0.69 10.6 3.8 1.9 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TMEM119 PF15724.5 GAP86981.1 - 0.22 11.6 2.8 0.34 10.9 2.8 1.2 1 0 0 1 1 1 0 TMEM119 family AAA_18 PF13238.6 GAP86981.1 - 0.24 12.0 0.1 0.24 12.0 0.1 2.6 2 1 0 2 2 2 0 AAA domain DUF2992 PF11208.8 GAP86981.1 - 2.9 8.1 11.0 5.5 7.2 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF5353 PF17304.2 GAP86982.1 - 3.1e-11 42.9 4.6 6e-11 41.9 4.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5353) CHCH PF06747.13 GAP86983.1 - 1.7e-06 28.0 5.7 3.1e-06 27.1 5.7 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 GAP86983.1 - 0.032 14.6 2.1 0.056 13.9 2.1 1.4 1 0 0 1 1 1 0 GCK domain FAM220 PF15487.6 GAP86983.1 - 0.56 9.8 6.6 0.16 11.6 3.6 1.6 2 0 0 2 2 2 0 FAM220 family TPK_catalytic PF04263.16 GAP86984.1 - 3.3e-23 82.0 0.0 4.6e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 GAP86984.1 - 6e-20 70.7 0.0 9.3e-20 70.1 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain PQQ_3 PF13570.6 GAP86984.1 - 0.025 15.0 0.2 0.077 13.5 0.2 1.8 1 0 0 1 1 1 0 PQQ-like domain DUF4577 PF15145.6 GAP86984.1 - 0.23 11.5 0.1 0.38 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) V-SNARE_C PF12352.8 GAP86985.1 - 1e-13 51.3 0.2 2.3e-13 50.2 0.2 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAP86985.1 - 0.00012 22.0 0.0 0.00033 20.5 0.0 1.7 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.16 GAP86985.1 - 0.015 14.8 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 E2F_TDP PF02319.20 GAP86985.1 - 0.043 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain DivIC PF04977.15 GAP86985.1 - 0.14 12.0 4.8 6.7 6.6 2.1 2.6 2 0 0 2 2 2 0 Septum formation initiator EP400_N PF15790.5 GAP86985.1 - 6.1 5.6 7.1 1.8 7.3 0.3 2.0 1 1 1 2 2 2 0 E1A-binding protein p400, N-terminal MFS_1 PF07690.16 GAP86986.1 - 7.7e-52 176.4 23.8 7.7e-52 176.4 23.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP86986.1 - 2.7e-13 49.6 10.0 2.7e-13 49.6 10.0 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAP86986.1 - 6.2e-12 44.7 4.8 9.7e-12 44.1 4.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 GAP86986.1 - 4.3e-07 28.7 7.7 4.3e-07 28.7 7.7 2.7 3 1 0 3 3 3 1 Transmembrane secretion effector MFS_5 PF05631.14 GAP86986.1 - 7.2e-05 21.9 1.9 7.2e-05 21.9 1.9 2.1 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM OATP PF03137.20 GAP86986.1 - 0.0012 17.2 0.3 0.013 13.9 0.0 2.5 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 GAP86986.1 - 0.025 13.5 7.7 0.23 10.3 7.7 2.7 1 1 0 1 1 1 0 MFS_1 like family Thiolase_N PF00108.23 GAP86988.1 - 6e-63 212.6 0.2 7.6e-63 212.3 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAP86988.1 - 1.6e-39 134.3 0.1 1.6e-39 134.3 0.1 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain Glyco_hydro_cc PF11790.8 GAP86989.1 - 8.1e-67 225.3 0.0 9.4e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Pro_CA PF00484.19 GAP86990.1 - 6.7e-50 169.4 0.5 1.6e-49 168.2 0.0 1.8 2 0 0 2 2 2 1 Carbonic anhydrase RAG2_PHD PF13341.6 GAP86991.1 - 0.11 12.6 0.3 0.22 11.6 0.3 1.5 1 0 0 1 1 1 0 RAG2 PHD domain CCDC106 PF15794.5 GAP86992.1 - 0.13 11.9 1.1 0.23 11.2 1.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CTP_transf_1 PF01148.20 GAP86993.1 - 3.8e-80 269.5 22.3 4.6e-80 269.2 22.3 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2304 PF10066.9 GAP86993.1 - 7.1 6.9 14.0 4.3 7.6 0.5 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) DUF3636 PF12331.8 GAP86994.1 - 2.7e-42 144.1 0.8 1.7e-41 141.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3636) TFIIA PF03153.13 GAP86994.1 - 0.00094 19.3 15.8 0.0015 18.6 15.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SKA1 PF07160.12 GAP86994.1 - 0.00098 19.0 3.0 0.00098 19.0 3.0 2.1 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 FAM76 PF16046.5 GAP86994.1 - 0.005 16.2 4.2 0.0076 15.7 4.2 1.1 1 0 0 1 1 1 1 FAM76 protein SARAF PF06682.12 GAP86994.1 - 0.077 12.6 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Dscam_C PF12355.8 GAP86994.1 - 0.33 11.9 6.8 1.1 10.2 0.7 2.7 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal DUF4551 PF15087.6 GAP86994.1 - 3 6.6 7.0 6 5.6 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NHL PF01436.21 GAP86995.1 - 0.025 14.6 0.1 7.3 6.8 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Rb_C PF08934.10 GAP86995.1 - 0.049 13.4 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Rb C-terminal domain SGL PF08450.12 GAP86995.1 - 0.06 12.9 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 GAP86995.1 - 0.067 13.2 0.0 4.5 7.3 0.0 2.8 2 0 0 2 2 2 0 Beta-propeller repeat Sugar_tr PF00083.24 GAP86996.1 - 1.9e-80 270.9 19.4 2.6e-80 270.5 19.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP86996.1 - 1.6e-17 63.5 46.1 1.2e-16 60.6 23.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2456 PF10445.9 GAP86996.1 - 0.44 10.7 7.2 5.6 7.1 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) SET PF00856.28 GAP86997.1 - 4.1e-11 43.6 0.1 2.9e-10 40.8 0.1 2.1 1 1 0 1 1 1 1 SET domain EGF_2 PF07974.13 GAP86998.1 - 0.00096 19.5 8.8 0.0019 18.5 8.8 1.5 1 0 0 1 1 1 1 EGF-like domain Nodulin_late PF07127.11 GAP86998.1 - 0.029 14.7 0.4 0.063 13.6 0.4 1.5 1 0 0 1 1 1 0 Late nodulin protein EB PF01683.18 GAP86998.1 - 0.11 12.7 4.1 0.21 11.9 4.1 1.3 1 0 0 1 1 1 0 EB module hEGF PF12661.7 GAP86998.1 - 0.34 11.6 2.0 0.82 10.4 2.0 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF Sulfate_transp PF00916.20 GAP86999.1 - 1.4e-77 261.0 10.8 1.9e-77 260.6 10.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAP86999.1 - 4.6e-18 64.9 0.0 8e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 GAP86999.1 - 0.0015 18.8 0.0 0.0037 17.6 0.0 1.7 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAP86999.1 - 0.011 16.2 3.4 0.011 16.2 3.4 2.6 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Cation_ATPase_C PF00689.21 GAP87000.1 - 4.6e-49 166.6 10.9 4.6e-49 166.6 10.9 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAP87000.1 - 8.2e-38 129.7 1.5 8.2e-38 129.7 1.5 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAP87000.1 - 1.1e-20 73.5 0.0 2.1e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAP87000.1 - 3.2e-19 70.0 0.5 7.5e-19 68.8 0.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAP87000.1 - 5.5e-12 45.2 0.4 2.9e-11 42.9 0.1 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAP87000.1 - 0.0023 17.7 0.1 0.0051 16.6 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase p450 PF00067.22 GAP87001.1 - 1.3e-68 231.9 0.0 1.7e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MaoC_dehydratas PF01575.19 GAP87002.1 - 1.3e-18 66.8 0.0 2.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 GAP87002.1 - 9.6e-05 22.5 0.0 0.014 15.6 0.0 2.4 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase ATG_C PF09333.11 GAP87003.1 - 0.0072 16.6 0.0 0.019 15.3 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF5336 PF17270.2 GAP87004.1 - 0.015 15.0 2.1 0.039 13.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5336) Sugar_tr PF00083.24 GAP87005.1 - 8.5e-123 410.5 32.9 9.7e-123 410.3 32.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP87005.1 - 5.4e-25 88.1 55.1 3.4e-18 65.7 31.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily C166 PF17615.2 GAP87006.1 - 1.9e-32 112.6 10.5 3.8e-31 108.4 10.5 2.1 1 1 0 1 1 1 1 Family of unknown function Fe-ADH_2 PF13685.6 GAP87006.1 - 0.055 13.2 0.1 0.064 12.9 0.1 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase HTH_47 PF16221.5 GAP87006.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 winged helix-turn-helix HET PF06985.11 GAP87007.1 - 8e-35 120.3 0.0 5.1e-34 117.7 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NTP_transferase PF00483.23 GAP87008.1 - 3.1e-36 125.2 0.0 6.9e-36 124.1 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 GAP87008.1 - 6.4e-13 47.9 10.8 1.7e-09 37.0 3.8 3.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAP87008.1 - 2.6e-05 23.9 2.8 2.6e-05 23.9 2.8 3.5 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 GAP87008.1 - 0.0017 16.6 0.1 0.0039 15.4 0.1 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 GAP87008.1 - 0.06 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain DND1_DSRM PF14709.7 GAP87009.1 - 0.007 16.6 0.3 0.011 16.0 0.3 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 GAP87009.1 - 0.0084 16.8 0.1 0.022 15.5 0.0 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Prenyltrans PF00432.21 GAP87010.1 - 1.7e-36 123.6 20.9 8.5e-11 41.4 0.4 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 GAP87010.1 - 0.021 13.9 0.1 2.6 7.1 0.0 2.3 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 GAP87010.1 - 0.028 13.5 0.0 0.1 11.7 0.1 1.8 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain Zn_clus PF00172.18 GAP87011.1 - 0.004 17.2 7.4 0.0081 16.3 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.12 GAP87011.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein ubiquitin PF00240.23 GAP87012.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 GAP87012.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAP87012.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 GAP87012.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 GAP87012.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAP87012.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAP87012.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 GAP87012.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 GAP87012.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 GAP87012.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 GAP87012.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 GAP87012.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 GAP87012.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 GAP87012.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 GAP87012.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 GAP87012.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 GAP87012.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 GAP87012.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 GAP87012.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 GAP87012.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 GAP87012.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 GAP87012.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 GAP87012.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 GAP87012.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 GAP87012.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 GAP87012.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 GAP87012.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain BRAP2 PF07576.12 GAP87013.1 - 2.2e-28 98.4 0.0 4e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 GAP87013.1 - 2.7e-17 62.8 9.0 2.7e-17 62.8 9.0 2.2 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 GAP87013.1 - 2.4e-08 34.2 8.1 2.4e-08 34.2 8.1 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAP87013.1 - 5.7e-07 29.3 8.5 1.4e-06 28.1 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP87013.1 - 3.1e-05 23.9 4.7 0.0003 20.8 5.2 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 GAP87013.1 - 9.6e-05 22.0 4.8 0.00038 20.1 4.8 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 GAP87013.1 - 0.00011 21.9 6.7 0.00032 20.5 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAP87013.1 - 0.00036 20.8 6.0 0.00098 19.4 6.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAP87013.1 - 0.0011 18.9 7.5 0.0011 18.9 7.5 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAP87013.1 - 0.0011 18.8 6.4 0.0011 18.8 6.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) NBD94 PF16830.5 GAP87013.1 - 0.0059 17.0 0.8 0.18 12.2 0.2 2.2 2 0 0 2 2 2 1 Nucleotide-Binding Domain 94 of RH DUF2031 PF09592.10 GAP87013.1 - 0.008 15.7 2.9 0.012 15.2 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2031) zf-ANAPC11 PF12861.7 GAP87013.1 - 0.0087 16.1 7.2 0.02 15.0 7.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 GAP87013.1 - 0.052 13.4 3.2 0.15 11.9 3.2 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein WD-3 PF09765.9 GAP87013.1 - 0.28 10.5 2.5 0.45 9.8 2.5 1.3 1 0 0 1 1 1 0 WD-repeat region GldM_N PF12081.8 GAP87013.1 - 0.35 10.9 6.4 0.57 10.3 6.4 1.2 1 0 0 1 1 1 0 GldM N-terminal domain YabA PF06156.13 GAP87013.1 - 0.4 11.4 11.7 0.56 10.9 3.4 2.4 1 1 1 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 GAP87013.1 - 0.94 9.9 18.6 2.3 8.7 2.1 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Cep57_CLD_2 PF14197.6 GAP87013.1 - 1 9.5 19.8 3.5 7.8 5.5 2.9 1 1 3 4 4 3 0 Centrosome localisation domain of PPC89 Cas_CXXC_CXXC PF09706.10 GAP87013.1 - 1.3 9.4 4.1 0.91 9.8 1.2 2.3 2 1 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF4200 PF13863.6 GAP87013.1 - 3 8.3 15.9 5 7.5 7.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) BST2 PF16716.5 GAP87013.1 - 4.2 8.0 13.1 1.4 9.5 1.4 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 PRKG1_interact PF15898.5 GAP87013.1 - 4.4 8.3 16.6 2.3 9.2 2.9 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 GAP87013.1 - 6.7 6.0 13.7 10 5.4 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 GAP87013.1 - 9.4 5.7 10.7 14 5.1 10.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Acyltransferase PF01553.21 GAP87014.1 - 2.3e-09 37.0 0.0 8.1e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Suc_Fer-like PF06999.12 GAP87015.1 - 1e-71 240.9 0.0 1.2e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pex14_N PF04695.13 GAP87016.1 - 1e-38 133.5 3.2 1e-38 133.5 3.2 3.6 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Golgin_A5 PF09787.9 GAP87016.1 - 0.0014 18.2 8.3 0.002 17.6 8.3 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 V-SNARE_C PF12352.8 GAP87016.1 - 0.0021 18.3 0.8 0.044 14.1 0.0 2.8 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus LMBR1 PF04791.16 GAP87016.1 - 0.0056 15.7 0.3 0.0075 15.2 0.3 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein FTA4 PF13093.6 GAP87016.1 - 0.024 14.5 0.2 0.058 13.3 0.0 1.6 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FUSC PF04632.12 GAP87016.1 - 0.051 12.1 2.1 0.074 11.6 2.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.11 GAP87016.1 - 0.11 11.3 10.7 0.16 10.8 10.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1043 PF06295.12 GAP87016.1 - 0.15 12.1 6.1 0.26 11.3 5.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Plasmid_RAQPRD PF09686.10 GAP87016.1 - 0.16 12.2 2.3 0.45 10.8 0.9 2.3 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TMPIT PF07851.13 GAP87016.1 - 0.28 10.4 4.8 0.43 9.8 4.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3584 PF12128.8 GAP87016.1 - 0.29 8.6 10.0 0.4 8.1 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 GAP87016.1 - 0.4 10.7 5.0 1.8 8.6 0.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 GAP87016.1 - 0.42 10.7 6.6 0.67 10.0 6.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 GAP87016.1 - 0.46 10.7 7.4 0.73 10.0 7.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cytochrom_B562 PF07361.11 GAP87016.1 - 0.54 10.9 4.0 0.83 10.3 3.3 1.7 1 1 0 1 1 1 0 Cytochrome b562 BST2 PF16716.5 GAP87016.1 - 1.2 9.7 7.3 0.98 10.1 4.3 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 V_ATPase_I PF01496.19 GAP87016.1 - 1.5 6.7 3.7 2 6.2 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 GAP87016.1 - 1.9 8.6 10.8 2.9 8.0 10.2 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4404 PF14357.6 GAP87016.1 - 2.6 8.8 7.3 2.2 9.0 5.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF2524 PF10732.9 GAP87016.1 - 3.2 8.1 6.3 7.1 7.0 4.0 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF2524) DUF4407 PF14362.6 GAP87016.1 - 3.7 6.8 6.4 5.6 6.2 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 GAP87016.1 - 3.7 7.6 8.7 14 5.7 7.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 GAP87016.1 - 4 7.7 11.7 0.033 14.5 1.2 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein CYSTM PF12734.7 GAP87016.1 - 4.9 7.6 7.2 12 6.3 7.2 1.7 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Muted PF14942.6 GAP87016.1 - 6.7 7.1 10.8 1.2 9.4 2.5 2.6 2 1 0 3 3 3 0 Organelle biogenesis, Muted-like protein Seryl_tRNA_N PF02403.22 GAP87016.1 - 7.1 6.9 12.1 22 5.3 10.5 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Abhydrolase_3 PF07859.13 GAP87017.1 - 8.6e-48 163.0 0.2 1.6e-47 162.1 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP87017.1 - 0.0026 16.7 0.0 0.0075 15.2 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase FAD_binding_4 PF01565.23 GAP87018.1 - 2e-14 53.5 0.1 4e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HMG_CoA_synt_C PF08540.10 GAP87019.1 - 7.5e-103 344.0 0.6 9.5e-103 343.7 0.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 GAP87019.1 - 2e-94 314.3 0.2 3.4e-94 313.6 0.2 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal BCS1_N PF08740.11 GAP87020.1 - 9.3e-56 188.8 3.5 9.3e-56 188.8 3.5 2.2 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 GAP87020.1 - 3.7e-16 59.7 0.0 2.9e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP87020.1 - 0.004 17.6 0.0 0.004 17.6 0.0 3.2 1 1 1 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 GAP87020.1 - 0.0095 15.9 0.0 0.032 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 GAP87020.1 - 0.014 15.0 0.0 0.035 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAP87020.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAP87020.1 - 0.35 11.1 2.4 0.74 10.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 GAP87020.1 - 0.43 10.3 0.0 0.43 10.3 0.0 3.3 2 1 0 2 2 1 0 AAA domain GREB1 PF15782.5 GAP87020.1 - 2 5.4 13.2 3 4.8 13.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_33 PF13671.6 GAP87020.1 - 2 8.5 0.0 2 8.5 0.0 3.4 3 1 0 3 3 2 0 AAA domain Herpes_UL6 PF01763.16 GAP87020.1 - 2.2 6.7 8.6 3.4 6.1 8.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like ABC_tran PF00005.27 GAP87020.1 - 3.1 8.3 0.0 3.1 8.3 0.0 3.6 3 1 0 3 3 2 0 ABC transporter Hydin_ADK PF17213.3 GAP87020.1 - 4.5 7.5 19.7 46 4.2 0.0 2.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain MDMPI_N PF11716.8 GAP87020.1 - 4.8 7.9 13.1 3.1 8.5 10.9 1.8 1 1 1 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain PAP1 PF08601.10 GAP87020.1 - 5.2 6.7 15.6 9.2 5.9 15.6 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Borrelia_P83 PF05262.11 GAP87020.1 - 7.6 4.9 37.2 12 4.2 37.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Apt1 PF10351.9 GAP87021.1 - 1.9 7.3 3.9 2 7.2 3.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pex14_N PF04695.13 GAP87021.1 - 2.2 8.9 5.6 3.9 8.1 5.6 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SMN PF06003.12 GAP87021.1 - 9.2 5.4 18.4 18 4.5 18.4 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Aminotran_5 PF00266.19 GAP87022.1 - 1.9e-13 50.1 0.0 2.8e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 GAP87022.1 - 0.088 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF3040 PF11239.8 GAP87023.1 - 1.2 9.4 4.1 0.68 10.2 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF4078 PF13300.6 GAP87024.1 - 4.7e-25 87.7 10.7 4.7e-25 87.7 10.7 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4078) RRF PF01765.19 GAP87024.1 - 0.057 13.4 0.7 0.57 10.1 0.7 2.2 2 0 0 2 2 2 0 Ribosome recycling factor DUF1764 PF08576.10 GAP87024.1 - 0.91 10.5 10.1 0.85 10.6 5.0 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Homoserine_dh PF00742.19 GAP87025.1 - 3.3e-51 173.6 0.0 4.6e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 GAP87025.1 - 1.8e-16 60.8 0.0 3e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_22 PF13401.6 GAP87025.1 - 0.077 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 GAP87026.1 - 7.7e-19 67.8 0.0 3e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Oxidored_q4 PF00507.19 GAP87027.1 - 6.9 6.9 11.6 0.092 12.9 1.9 2.4 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 AMP-binding PF00501.28 GAP87028.1 - 3.9e-72 243.2 0.0 6.4e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme KR PF08659.10 GAP87028.1 - 2.1e-52 177.6 1.6 7.5e-50 169.3 0.2 3.0 3 0 0 3 3 3 2 KR domain ketoacyl-synt PF00109.26 GAP87028.1 - 1.2e-51 175.7 0.3 2.6e-51 174.7 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 GAP87028.1 - 9.2e-31 106.9 0.0 3.6e-30 105.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Condensation PF00668.20 GAP87028.1 - 3.6e-29 101.7 0.0 1.2e-13 50.5 0.5 2.2 1 1 1 2 2 2 2 Condensation domain Ketoacyl-synt_C PF02801.22 GAP87028.1 - 8.3e-29 100.0 0.0 1.7e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 GAP87028.1 - 4.4e-17 62.2 0.8 2.5e-11 43.7 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 GAP87028.1 - 7e-12 45.2 3.4 1e-09 38.1 0.1 2.5 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 GAP87028.1 - 7e-07 28.9 0.1 0.0008 18.9 0.1 2.7 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAP87028.1 - 1.4e-05 24.3 0.2 0.0017 17.4 0.2 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 GAP87028.1 - 1.7e-05 24.3 0.0 3.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C PF13193.6 GAP87028.1 - 0.00096 20.1 0.3 0.0056 17.6 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NmrA PF05368.13 GAP87028.1 - 0.077 12.5 0.1 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.25 GAP87029.1 - 0.25 10.8 0.0 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.16 GAP87030.1 - 5.3e-12 45.3 39.2 3.3e-11 42.7 39.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 GAP87030.1 - 0.0031 16.2 2.3 0.0031 16.2 2.3 1.6 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like Multi_Drug_Res PF00893.19 GAP87030.1 - 7.1 7.4 8.0 1.9 9.2 3.9 2.2 1 1 0 2 2 2 0 Small Multidrug Resistance protein UCR_hinge PF02320.16 GAP87031.1 - 2.8e-26 91.5 10.1 2.8e-26 91.5 10.1 1.6 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF4211 PF13926.6 GAP87031.1 - 0.067 13.3 2.6 0.089 12.8 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) BUD22 PF09073.10 GAP87031.1 - 0.089 12.1 13.7 0.1 12.0 13.7 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 GAP87031.1 - 0.11 10.8 7.1 0.1 10.9 7.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3391 PF11871.8 GAP87031.1 - 0.12 12.9 9.1 0.16 12.5 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF4471 PF14740.6 GAP87031.1 - 0.14 11.4 1.7 0.16 11.2 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) RR_TM4-6 PF06459.12 GAP87031.1 - 0.23 11.2 11.5 0.3 10.9 11.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Bcl-2_BAD PF10514.9 GAP87031.1 - 0.32 11.5 0.1 0.32 11.5 0.1 2.0 1 1 1 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD CPSF100_C PF13299.6 GAP87031.1 - 0.67 10.1 4.1 0.84 9.8 4.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDRGK PF09756.9 GAP87031.1 - 0.86 9.2 13.8 1.1 8.9 13.8 1.1 1 0 0 1 1 1 0 DDRGK domain Sigma70_ner PF04546.13 GAP87031.1 - 1.2 8.9 17.1 1.9 8.3 17.1 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region DUF913 PF06025.12 GAP87031.1 - 1.5 7.7 4.9 1.6 7.7 4.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GAP87031.1 - 1.6 7.4 7.3 1.9 7.1 7.3 1.0 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 GAP87031.1 - 1.8 7.3 5.9 2 7.1 5.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim54 PF11711.8 GAP87031.1 - 1.8 7.2 10.6 2 7.1 10.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 GAP87031.1 - 2.2 7.7 7.8 2.4 7.5 7.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Mitofilin PF09731.9 GAP87031.1 - 2.5 6.8 13.5 2.8 6.7 13.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2052 PF09747.9 GAP87031.1 - 2.6 8.2 18.7 3.3 7.8 18.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Neur_chan_memb PF02932.16 GAP87031.1 - 2.8 7.9 4.0 3 7.8 4.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRN3 PF05327.11 GAP87031.1 - 3 6.3 7.4 3.3 6.2 7.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GAP87031.1 - 4.9 5.2 16.3 5.4 5.1 16.3 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAP87031.1 - 5.9 6.2 16.6 7.5 5.9 16.6 1.2 1 0 0 1 1 1 0 SDA1 GET2 PF08690.10 GAP87031.1 - 6.1 6.4 5.5 6.6 6.3 5.5 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 PTPRCAP PF15713.5 GAP87031.1 - 9.4 6.5 21.2 18 5.6 21.2 1.5 1 1 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Vps36_ESCRT-II PF11605.8 GAP87032.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Drf_GBD PF06371.13 GAP87033.1 - 8.7e-14 51.5 0.7 8.7e-14 51.5 0.7 2.7 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Methyltransf_4 PF02390.17 GAP87034.1 - 5.1e-54 182.3 0.0 7.6e-54 181.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 GAP87034.1 - 0.0013 19.4 0.0 0.0031 18.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP87034.1 - 0.0027 18.4 0.0 0.008 16.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP87034.1 - 0.014 14.9 0.0 0.052 13.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 GAP87034.1 - 0.036 13.9 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 GAP87034.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PXA PF02194.15 GAP87035.1 - 9.1e-52 175.7 0.7 9.1e-52 175.7 0.7 2.8 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 GAP87035.1 - 6.4e-27 94.3 0.1 2.5e-26 92.5 0.1 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 GAP87035.1 - 1.8e-22 79.4 0.5 3.4e-21 75.3 0.3 2.4 2 0 0 2 2 2 1 PX domain RGS PF00615.19 GAP87035.1 - 2.4e-08 34.3 0.0 7e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain HeH PF12949.7 GAP87035.1 - 0.013 15.2 0.1 0.039 13.7 0.1 1.8 1 0 0 1 1 1 0 HeH/LEM domain GyrB_insert PF18053.1 GAP87035.1 - 0.052 13.4 0.8 0.3 10.9 0.8 2.3 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain GST_C PF00043.25 GAP87036.1 - 1.8e-15 56.9 0.1 1e-14 54.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP87036.1 - 1.6e-09 37.6 0.0 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAP87036.1 - 6.3e-08 32.9 0.0 1.8e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAP87036.1 - 2.5e-07 30.8 0.0 8.1e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAP87036.1 - 5.6e-06 26.7 0.0 1.8e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAP87036.1 - 5.9e-05 23.3 0.0 0.00015 22.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glyco_hydro_79C PF16862.5 GAP87037.1 - 1.1e-07 32.7 0.0 3.1e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Rad4 PF03835.15 GAP87039.1 - 3e-30 104.8 0.2 3e-30 104.8 0.2 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 GAP87039.1 - 2e-25 89.0 0.0 3.4e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 GAP87039.1 - 1.2e-21 76.2 0.0 2.6e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 GAP87039.1 - 2.4e-16 60.4 0.1 2.4e-16 60.4 0.1 3.6 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 GAP87039.1 - 0.00024 21.5 0.2 0.0013 19.2 0.0 2.3 2 1 0 2 2 2 1 Transglutaminase-like superfamily AP3D1 PF06375.11 GAP87039.1 - 3.6 7.8 15.6 9.5 6.4 15.6 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 ABC_tran PF00005.27 GAP87040.1 - 3.1e-47 160.5 0.3 6e-26 91.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 GAP87040.1 - 8.3e-24 84.3 37.6 8.4e-13 48.1 23.1 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 GAP87040.1 - 3.4e-19 69.8 3.3 0.00012 22.0 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAP87040.1 - 7.8e-08 31.9 2.6 0.0018 18.0 0.4 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 GAP87040.1 - 1.7e-07 30.9 3.8 0.18 11.2 0.0 4.5 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAP87040.1 - 2.4e-05 24.9 4.9 0.018 15.5 0.7 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAP87040.1 - 0.00011 22.1 1.0 0.35 10.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 GAP87040.1 - 0.00039 20.1 0.5 0.036 13.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAP87040.1 - 0.0018 18.7 0.1 2.1 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 GAP87040.1 - 0.003 17.3 0.0 6.3 6.4 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain DUF4162 PF13732.6 GAP87040.1 - 0.003 18.2 0.0 0.044 14.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_22 PF13401.6 GAP87040.1 - 0.0097 16.2 0.1 5.2 7.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain FAD_binding_4 PF01565.23 GAP87040.1 - 0.016 14.9 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain AAA_30 PF13604.6 GAP87040.1 - 0.02 14.6 0.6 5.6 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 GAP87040.1 - 0.036 14.0 0.0 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain SRP54 PF00448.22 GAP87040.1 - 0.041 13.5 0.9 6.4 6.4 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 GAP87040.1 - 0.07 12.4 0.8 14 4.9 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_17 PF13207.6 GAP87040.1 - 0.072 13.5 0.5 6.8 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAP87040.1 - 0.11 12.9 0.0 12 6.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase MukB PF04310.12 GAP87040.1 - 0.35 10.7 1.2 15 5.3 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AIG1 PF04548.16 GAP87040.1 - 0.98 8.7 2.3 4.2 6.6 0.8 2.4 2 0 0 2 2 2 0 AIG1 family DUF87 PF01935.17 GAP87040.1 - 6.5 6.8 7.1 13 5.7 0.1 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain HATPase_c PF02518.26 GAP87041.1 - 9.8e-19 67.9 0.1 1.8e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAP87041.1 - 8.6e-18 64.5 0.1 2.1e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 GAP87041.1 - 7.9e-09 35.4 0.0 2.1e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain SelP_N PF04592.14 GAP87041.1 - 1.3 8.4 12.5 2.3 7.6 12.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3295 PF11702.8 GAP87045.1 - 2.4e-152 508.8 42.6 7.9e-152 507.1 42.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 GAP87045.1 - 7.2e-12 44.9 2.3 1.6e-11 43.8 2.3 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn_ribbon_SprT PF17283.2 GAP87046.1 - 0.049 13.6 5.0 0.09 12.7 0.3 3.2 3 0 0 3 3 3 0 SprT-like zinc ribbon domain RWD PF05773.22 GAP87046.1 - 0.093 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain zf-trcl PF13451.6 GAP87046.1 - 0.19 11.6 0.1 0.19 11.6 0.1 3.0 4 0 0 4 4 4 0 Probable zinc-ribbon domain HNH_5 PF14279.6 GAP87046.1 - 4.3 7.3 4.8 30 4.5 0.0 3.2 4 0 0 4 4 4 0 HNH endonuclease DUF2688 PF10892.8 GAP87046.1 - 9.2 5.8 6.3 3.1 7.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) Glyco_hydro_17 PF00332.18 GAP87049.1 - 1.5e-05 24.7 0.3 2.5e-05 24.0 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF1180 PF06679.12 GAP87049.1 - 1.1 9.6 4.5 1.8 9.0 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RAP1 PF07218.11 GAP87049.1 - 4.2 5.5 15.0 5.9 5.0 15.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_L9_N PF01281.19 GAP87052.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain RCC1 PF00415.18 GAP87053.1 - 1.2e-19 70.6 4.9 0.0013 19.3 0.0 6.5 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 GAP87053.1 - 7e-13 48.8 0.0 3.6e-10 40.1 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 GAP87053.1 - 3.5e-12 46.6 0.2 1.2e-08 35.3 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.6 GAP87053.1 - 8.4e-08 31.8 0.4 8.4e-08 31.8 0.4 4.9 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.6 GAP87053.1 - 2.2e-06 27.5 0.2 0.17 12.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 GAP87053.1 - 5.2e-06 27.0 0.0 1.2e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP87053.1 - 0.014 15.7 0.0 0.1 13.0 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Mito_carr PF00153.27 GAP87054.1 - 4.1e-66 219.0 1.4 2.8e-24 84.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 GAP87054.1 - 0.012 16.0 1.0 0.044 14.2 1.0 2.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Vfa1 PF08432.10 GAP87055.1 - 0.87 9.9 11.1 2.3 8.5 11.1 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.13 GAP87055.1 - 2.6 6.7 12.6 5 5.8 12.6 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 GAP87055.1 - 3 6.5 7.4 5.3 5.7 7.4 1.3 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 GAP87056.1 - 2.6e-96 323.6 36.6 5e-96 322.7 36.6 1.4 1 1 0 1 1 1 1 BUD22 Nop14 PF04147.12 GAP87056.1 - 0.82 7.8 16.2 1.2 7.2 16.2 1.4 1 0 0 1 1 1 0 Nop14-like family Mito_carr PF00153.27 GAP87057.1 - 8.4e-55 182.7 4.2 2.6e-18 65.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 GAP87059.1 - 1.3e-51 175.8 0.0 2e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Amidoligase_2 PF12224.8 GAP87060.1 - 8.2e-17 61.7 0.0 4.5e-13 49.5 0.0 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme MSG PF02349.15 GAP87060.1 - 0.11 12.7 3.7 5.5 7.3 0.1 2.5 3 0 0 3 3 3 0 Major surface glycoprotein Ada_Zn_binding PF02805.16 GAP87061.1 - 5.1e-27 93.7 5.5 9.5e-27 92.8 5.5 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 GAP87061.1 - 3.9e-09 36.4 0.0 1.4e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 GAP87061.1 - 1.8e-07 31.3 0.0 4.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1203 PF06718.11 GAP87062.1 - 1.6e-28 99.3 0.1 2.1e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1203) Transferase PF02458.15 GAP87063.1 - 2.4e-11 43.0 0.0 1.3e-07 30.6 0.0 2.7 2 1 0 2 2 2 2 Transferase family Pyr_redox_2 PF07992.14 GAP87064.1 - 6.1e-14 51.9 0.1 4.2e-11 42.6 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAP87064.1 - 0.00024 20.1 0.4 0.00043 19.3 0.2 1.5 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 GAP87064.1 - 0.00038 20.2 0.9 0.0026 17.4 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAP87064.1 - 0.00074 18.8 0.1 0.0015 17.8 0.1 1.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 GAP87064.1 - 0.00081 19.6 0.2 0.0035 17.6 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 GAP87064.1 - 0.0091 15.3 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 GAP87064.1 - 0.02 14.0 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 GAP87064.1 - 0.03 14.3 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAP87064.1 - 0.042 13.2 5.5 0.5 9.7 3.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 GAP87064.1 - 0.069 12.2 1.1 0.17 10.9 1.4 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAP87064.1 - 0.078 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 GAP87064.1 - 0.13 10.9 0.2 0.23 10.1 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 GAP87064.1 - 0.15 11.3 0.2 0.48 9.6 0.0 1.9 3 0 0 3 3 3 0 FAD binding domain Pyr_redox PF00070.27 GAP87064.1 - 0.15 12.6 1.0 0.72 10.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP87064.1 - 0.18 11.0 1.0 0.76 9.0 0.5 2.0 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 GAP87065.1 - 5.8e-41 140.7 0.0 8.2e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.11 GAP87065.1 - 0.077 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Aminotran_4 PF01063.19 GAP87066.1 - 1.9e-10 41.0 0.0 2.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV 4HBT_2 PF13279.6 GAP87067.1 - 2.2e-07 31.4 0.0 3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Ank_3 PF13606.6 GAP87068.1 - 1.1e-17 62.3 1.4 6.6e-05 23.0 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 GAP87068.1 - 1.7e-17 63.6 0.4 5.8e-07 29.9 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP87068.1 - 2.2e-17 63.4 0.0 4.6e-08 33.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP87068.1 - 2.9e-14 52.9 1.1 0.00011 22.5 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAP87068.1 - 4.6e-12 45.8 3.5 0.0038 17.6 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat bZIP_2 PF07716.15 GAP87068.1 - 0.053 13.6 4.4 0.1 12.7 4.4 1.4 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 GAP87068.1 - 0.14 12.2 7.7 0.25 11.4 7.7 1.3 1 0 0 1 1 1 0 bZIP transcription factor AMP-binding PF00501.28 GAP87069.1 - 4.9e-142 473.4 0.0 4.2e-76 256.2 0.0 5.1 5 1 0 5 5 5 4 AMP-binding enzyme Condensation PF00668.20 GAP87069.1 - 4.1e-100 335.6 0.0 1.4e-34 119.6 0.0 7.1 6 1 0 6 6 6 6 Condensation domain PP-binding PF00550.25 GAP87069.1 - 3.6e-21 75.3 0.3 8.7e-08 32.4 0.0 4.3 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAP87069.1 - 0.001 20.0 0.0 0.0044 18.0 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 GAP87070.1 - 6.1e-40 137.2 41.6 6.1e-40 137.2 41.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP87070.1 - 5.1e-12 45.0 13.7 5.1e-12 45.0 13.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 GAP87070.1 - 5.1 5.3 9.1 15 3.7 8.2 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 GAP87071.1 - 3.8e-18 65.7 0.1 5e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87071.1 - 2.4e-10 40.4 0.1 3.3e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87071.1 - 8.2e-10 38.9 0.2 1.2e-09 38.3 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAP87071.1 - 0.058 13.3 3.8 0.11 12.3 3.8 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 GAP87071.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 GAP87072.1 - 5.5e-53 179.9 0.6 6.6e-53 179.7 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP87072.1 - 4.1e-35 121.0 0.1 5.2e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP87072.1 - 4.7e-09 36.4 1.5 7.3e-09 35.8 1.5 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAP87072.1 - 0.00084 18.6 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 GAP87072.1 - 0.0015 18.7 1.0 0.0023 18.0 0.1 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GAP87072.1 - 0.0072 16.2 0.2 0.0072 16.2 0.2 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAP87072.1 - 0.02 14.3 0.1 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 GAP87072.1 - 0.12 11.8 0.5 0.42 10.0 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family FliG_C PF01706.16 GAP87072.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.2 1 0 0 1 1 1 0 FliG C-terminal domain GDP_Man_Dehyd PF16363.5 GAP87072.1 - 0.2 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FAD_binding_4 PF01565.23 GAP87073.1 - 8.1e-16 58.0 0.0 1.8e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP87073.1 - 3.8e-06 26.9 0.4 7.8e-06 25.9 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF4265 PF14085.6 GAP87073.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) p450 PF00067.22 GAP87074.1 - 1e-59 202.5 0.0 1.2e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAP87075.1 - 1.8e-54 185.3 0.0 2.3e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fas_alpha_ACP PF18325.1 GAP87076.1 - 2.4e-50 171.1 0.0 1.1e-49 169.0 0.0 2.1 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 GAP87076.1 - 4.4e-45 153.8 0.0 7.8e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 GAP87076.1 - 6.6e-22 78.3 0.1 1.2e-21 77.5 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAP87076.1 - 3.5e-12 46.4 0.0 1e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short_C2 PF13561.6 GAP87076.1 - 0.00051 19.7 0.0 0.00095 18.8 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.22 GAP87077.1 - 1.2e-61 208.9 0.0 1.9e-61 208.3 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Goodbye PF17109.5 GAP87077.1 - 0.15 12.5 0.0 0.7 10.3 0.0 2.0 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Nab2 PF11517.8 GAP87077.1 - 0.22 11.9 0.0 0.41 11.0 0.0 1.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Serglycin PF04360.12 GAP87078.1 - 0.88 9.5 6.4 1.4 8.8 6.4 1.2 1 0 0 1 1 1 0 Serglycin Thiolase_N PF00108.23 GAP87079.1 - 2.7e-72 243.3 3.3 3.8e-72 242.8 3.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAP87079.1 - 2.9e-44 149.6 0.2 7.3e-44 148.4 0.1 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 GAP87079.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal OCD_Mu_crystall PF02423.15 GAP87080.1 - 9.4e-11 41.2 0.1 2.7e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 GAP87080.1 - 0.0034 17.5 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pro_CA PF00484.19 GAP87081.1 - 4.6e-46 157.0 0.1 5.6e-46 156.7 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L7Ae PF01248.26 GAP87082.1 - 1.7e-19 69.3 0.7 3.1e-19 68.5 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATP_bind_3 PF01171.20 GAP87083.1 - 2.1e-18 66.8 0.0 3.3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 GAP87083.1 - 2.2e-18 65.4 3.7 2.2e-18 65.4 3.7 3.5 3 0 0 3 3 3 1 Zinc-ribbon tRNA_Me_trans PF03054.16 GAP87083.1 - 0.0077 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.15 GAP87083.1 - 0.011 15.3 1.0 0.011 15.3 1.0 3.0 4 0 0 4 4 4 0 RecR protein MWFE PF15879.5 GAP87084.1 - 7.4e-32 109.3 0.6 9.2e-32 109.0 0.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit MOZ_SAS PF01853.18 GAP87085.1 - 8.7e-77 256.8 0.0 1.2e-76 256.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAP87085.1 - 7.5e-21 73.5 3.7 1.5e-20 72.6 3.7 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 GAP87085.1 - 0.08 13.4 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M28 PF04389.17 GAP87086.1 - 5e-34 117.7 0.0 7.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 ENTH PF01417.20 GAP87087.1 - 9.3e-48 161.4 0.0 1.7e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 GAP87087.1 - 8.1e-05 22.3 3.0 0.0072 16.2 0.2 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 GAP87087.1 - 0.002 17.2 0.0 0.0036 16.3 0.0 1.4 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.6 GAP87087.1 - 0.0052 16.4 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) VHS PF00790.19 GAP87087.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 VHS domain AAR2 PF05282.11 GAP87087.1 - 1.5 8.1 5.6 0.5 9.7 0.0 2.4 2 1 1 3 3 3 0 AAR2 protein EF-hand_7 PF13499.6 GAP87088.1 - 6e-15 55.5 0.2 9.6e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAP87088.1 - 6.1e-15 53.6 6.3 3.1e-05 23.2 0.7 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 GAP87088.1 - 8.2e-14 50.3 4.7 3.6e-05 23.4 0.9 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 GAP87088.1 - 2.5e-12 46.4 1.6 5e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 GAP87088.1 - 2.3e-06 26.8 3.1 0.04 13.4 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 GAP87088.1 - 0.026 14.5 0.8 0.28 11.2 0.3 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 GAP87088.1 - 0.04 14.3 0.0 1.9 8.9 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain Caleosin PF05042.13 GAP87088.1 - 0.092 12.7 0.0 7.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein Nup96 PF12110.8 GAP87089.1 - 3e-91 305.6 0.9 4.3e-91 305.0 0.9 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 GAP87089.1 - 7e-48 162.5 0.0 1.2e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 GAP87089.1 - 5.1e-20 72.1 322.4 6.7e-08 33.3 35.2 10.9 5 2 6 11 11 11 8 Nucleoporin FG repeat region DUF5026 PF16429.5 GAP87089.1 - 0.046 13.8 0.1 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5026) SIR2 PF02146.17 GAP87090.1 - 4.9e-56 189.4 0.0 8e-56 188.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 GAP87090.1 - 0.0012 18.6 0.1 2 8.1 0.1 2.7 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 GAP87090.1 - 0.002 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) Cation_ATPase_C PF00689.21 GAP87091.1 - 2.2e-42 144.8 7.5 2.2e-42 144.8 7.5 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 GAP87091.1 - 2.3e-32 112.0 0.4 2.3e-32 112.0 0.4 3.5 5 0 0 5 5 5 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAP87091.1 - 3.6e-22 78.2 0.0 7.5e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAP87091.1 - 1.2e-20 74.7 0.4 3.3e-20 73.3 0.4 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAP87091.1 - 1.8e-09 37.1 0.0 1.1e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAP87091.1 - 0.00016 21.5 0.8 0.0006 19.6 0.5 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 GAP87091.1 - 0.03 13.2 2.7 0.04 12.8 1.5 1.8 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG HAD PF12710.7 GAP87091.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2976 PF11190.8 GAP87091.1 - 0.24 11.2 5.0 0.25 11.2 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Zn_clus PF00172.18 GAP87092.1 - 1.1e-05 25.5 13.7 2.2e-05 24.5 13.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_6 PF12913.7 GAP87093.1 - 0.035 13.6 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) Flavokinase PF01687.17 GAP87094.1 - 2.8e-33 114.5 0.0 3.6e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PAS PF00989.25 GAP87095.1 - 0.014 15.4 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 PAS fold Zn_clus PF00172.18 GAP87095.1 - 0.014 15.5 7.9 0.014 15.5 7.9 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5093 PF17011.5 GAP87095.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) Cellulase PF00150.18 GAP87096.1 - 7.1e-11 42.1 0.0 7.1e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF3328 PF11807.8 GAP87096.1 - 0.002 18.0 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) EphA2_TM PF14575.6 GAP87096.1 - 0.0089 16.9 0.0 0.0089 16.9 0.0 2.2 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain Synaptobrevin PF00957.21 GAP87096.1 - 0.0095 15.7 0.2 0.015 15.0 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Protocadherin PF08374.11 GAP87096.1 - 0.097 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Protocadherin Radical_SAM PF04055.21 GAP87096.1 - 0.17 12.3 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily RCR PF12273.8 GAP87096.1 - 0.24 12.1 12.0 1.3 9.6 0.3 2.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red ORC6 PF05460.13 GAP87096.1 - 0.61 9.3 4.7 0.96 8.6 4.7 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Transket_pyr PF02779.24 GAP87097.1 - 1.4e-44 151.9 0.0 2.2e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAP87097.1 - 1.1e-31 109.3 0.0 2.9e-31 107.9 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 GAP87097.1 - 0.02 15.2 0.0 0.065 13.5 0.0 1.8 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II F-actin_cap_A PF01267.17 GAP87098.1 - 3.6e-97 325.0 0.0 4.1e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ACAS_N PF16177.5 GAP87098.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus CSTF2_hinge PF14327.6 GAP87098.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Cyt-b5 PF00173.28 GAP87099.1 - 1.3e-23 82.9 0.3 1.6e-23 82.6 0.3 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF347 PF03988.12 GAP87099.1 - 0.032 14.4 0.1 0.044 14.0 0.1 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) KleE PF17394.2 GAP87099.1 - 0.035 14.3 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein U62_UL91 PF17442.2 GAP87099.1 - 0.052 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins NACHT PF05729.12 GAP87100.1 - 1.1e-10 41.7 0.2 2.3e-09 37.4 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 GAP87100.1 - 0.00049 20.4 0.0 0.0028 17.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP87100.1 - 0.0012 19.3 0.0 0.0045 17.4 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 GAP87100.1 - 0.0092 16.5 0.0 0.092 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAP87100.1 - 0.0096 16.4 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 GAP87100.1 - 0.012 16.1 1.7 0.052 14.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 GAP87100.1 - 0.017 15.5 0.0 1.1 9.7 0.0 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAP87100.1 - 0.022 15.2 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 GAP87100.1 - 0.026 14.7 0.0 0.07 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAP87100.1 - 0.038 14.1 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase SesA PF17107.5 GAP87100.1 - 0.038 14.2 1.0 0.13 12.4 0.6 2.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_29 PF13555.6 GAP87100.1 - 0.052 13.3 0.0 0.23 11.2 0.0 2.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helo_like_N PF17111.5 GAP87100.1 - 0.054 12.9 0.5 0.14 11.5 0.5 1.7 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins NleF_casp_inhib PF16809.5 GAP87100.1 - 0.061 13.2 1.1 2.7 7.9 0.3 2.9 2 1 0 2 2 2 0 NleF caspase inhibitor cobW PF02492.19 GAP87100.1 - 0.076 12.6 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AbiEi_4 PF13338.6 GAP87100.1 - 0.15 12.3 0.0 0.47 10.6 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin TFA2_Winged_2 PF18121.1 GAP87101.1 - 2.9e-19 68.5 0.1 4.7e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 GAP87101.1 - 1.5e-09 38.0 1.9 3.8e-09 36.7 1.4 2.0 2 1 0 2 2 2 1 TFIIE beta subunit core domain Methyltransf_12 PF08242.12 GAP87101.1 - 0.26 12.0 0.8 0.84 10.4 0.8 2.0 1 1 0 1 1 1 0 Methyltransferase domain Menin PF05053.13 GAP87101.1 - 0.36 9.1 4.6 0.53 8.6 4.6 1.2 1 0 0 1 1 1 0 Menin DUF3583 PF12126.8 GAP87101.1 - 0.45 9.9 4.3 0.88 9.0 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) SPX PF03105.19 GAP87101.1 - 0.74 9.7 12.0 0.41 10.5 9.9 1.5 1 1 1 2 2 2 0 SPX domain Ribosomal_60s PF00428.19 GAP87101.1 - 1.1 9.9 13.8 11 6.7 0.0 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein SOG2 PF10428.9 GAP87101.1 - 1.7 7.8 15.9 0.076 12.2 10.6 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein DSBA PF01323.20 GAP87102.1 - 2.7e-09 37.1 0.0 1.5e-05 24.8 0.0 2.5 2 1 0 2 2 2 2 DSBA-like thioredoxin domain zf-C2H2 PF00096.26 GAP87103.1 - 1.5e-17 63.0 31.2 3.7e-05 23.9 1.7 5.0 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP87103.1 - 1.4e-16 60.1 25.3 5.9e-05 23.3 0.9 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP87103.1 - 1.6e-09 37.7 23.8 0.0042 17.8 1.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP87103.1 - 0.00028 21.1 1.6 1.8 8.9 0.0 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 GAP87103.1 - 0.015 14.9 1.6 1.2 8.8 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 GAP87103.1 - 0.02 14.6 0.8 0.02 14.6 0.8 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 GAP87103.1 - 0.12 12.8 9.3 3.4 8.2 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 GAP87103.1 - 0.16 11.6 4.7 4.5 7.0 0.1 3.4 3 0 0 3 3 3 0 MYST family zinc finger domain C1_4 PF07975.12 GAP87103.1 - 0.22 11.8 0.8 5.5 7.3 0.0 2.6 3 0 0 3 3 3 0 TFIIH C1-like domain Glyco_hydro_9 PF00759.19 GAP87103.1 - 0.36 10.2 3.0 0.7 9.3 3.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DUF2256 PF10013.9 GAP87103.1 - 0.52 10.5 2.8 23 5.2 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CRD PF17979.1 GAP87103.1 - 2.4 8.3 7.0 1.7 8.8 1.6 2.1 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions XPA_N PF01286.18 GAP87103.1 - 3.2 7.9 5.6 0.87 9.7 0.5 2.5 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2HC_2 PF13913.6 GAP87103.1 - 9.7 6.2 7.5 47 4.0 0.4 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Acetyltransf_10 PF13673.7 GAP87105.1 - 3.4e-07 30.3 0.0 5.2e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP87105.1 - 0.00021 21.6 0.0 0.00039 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP87105.1 - 0.0074 16.5 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NAD_binding_4 PF07993.12 GAP87106.1 - 2e-29 102.5 0.0 2.9e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAP87106.1 - 8.9e-24 83.9 0.0 1.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAP87106.1 - 5.8e-07 29.2 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAP87106.1 - 0.00019 21.7 0.5 0.00058 20.2 0.5 1.9 1 1 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 GAP87106.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase zf-RING_2 PF13639.6 GAP87107.1 - 6.7e-11 42.4 1.6 8.9e-11 42.0 1.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAP87107.1 - 2.2e-06 27.8 3.1 1e-05 25.7 3.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAP87107.1 - 2.5e-06 27.4 2.2 4.9e-06 26.5 2.2 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAP87107.1 - 4.4e-05 23.2 1.9 7.3e-05 22.5 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP87107.1 - 0.00013 21.8 0.6 0.00027 20.7 0.5 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP87107.1 - 0.00031 20.6 0.4 0.00046 20.0 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAP87107.1 - 0.00064 19.7 0.6 0.0011 19.0 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAP87107.1 - 0.00078 19.3 2.0 0.16 11.8 0.2 2.2 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 GAP87107.1 - 0.0025 17.5 2.0 0.0026 17.5 0.3 1.9 2 0 0 2 2 2 1 RING-like zinc finger Rad50_zn_hook PF04423.14 GAP87107.1 - 0.0096 15.7 0.2 0.38 10.6 0.0 2.6 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-Di19 PF05605.12 GAP87107.1 - 0.015 15.6 0.4 7.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 GAP87107.1 - 0.027 14.9 2.3 0.61 10.6 0.1 2.3 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-UDP PF14569.6 GAP87107.1 - 0.066 13.3 0.5 0.46 10.6 0.1 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zinc_ribbon_9 PF14369.6 GAP87107.1 - 0.085 13.1 3.5 0.3 11.4 0.2 2.5 3 0 0 3 3 2 0 zinc-ribbon zf-C4_Topoisom PF01396.19 GAP87107.1 - 0.089 12.6 1.8 0.25 11.2 0.2 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-RING_5 PF14634.6 GAP87107.1 - 0.11 12.4 0.7 0.28 11.2 0.8 1.6 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_1 PF14446.6 GAP87107.1 - 0.15 12.0 1.5 5.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 GAP87107.1 - 0.21 11.8 1.5 9.6 6.5 1.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain CAP_N PF01213.19 GAP87108.1 - 3.8 6.9 5.0 1.3 8.4 2.8 1.3 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ank_3 PF13606.6 GAP87110.1 - 1.5e-07 31.1 0.0 0.00072 19.8 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 GAP87110.1 - 2.3e-07 31.3 0.0 0.019 15.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP87110.1 - 2.6e-06 27.6 0.5 0.002 18.4 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAP87110.1 - 0.00011 22.4 0.1 0.0035 17.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 GAP87110.1 - 0.00013 22.4 0.4 0.48 11.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ntox43 PF15537.6 GAP87110.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 43 Piwi PF02171.17 GAP87111.1 - 2.2e-78 263.6 0.0 2.8e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 GAP87111.1 - 6.8e-10 38.5 0.0 1.8e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 GAP87111.1 - 2.1e-09 37.6 0.1 6.6e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 GAP87111.1 - 2.7e-07 30.5 0.0 6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 GAP87111.1 - 9.6e-06 26.3 0.0 3.4e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 N-terminal domain of argonaute Phytoreo_P8 PF07124.11 GAP87111.1 - 0.082 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 Inv-AAD PF18785.1 GAP87112.1 - 2.5e-58 195.5 0.2 3e-58 195.3 0.2 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 GAP87112.1 - 2.1e-14 53.2 0.0 3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAP87112.1 - 0.00075 19.3 0.0 0.001 18.8 0.0 1.3 1 1 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 GAP87112.1 - 0.0027 17.6 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Herpes_U47 PF05467.11 GAP87112.1 - 0.067 11.3 0.0 0.091 10.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 SNAD4 PF18750.1 GAP87112.1 - 0.092 12.9 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DnaJ PF00226.31 GAP87113.1 - 2.2e-23 82.2 1.0 5.8e-23 80.8 1.0 1.8 1 0 0 1 1 1 1 DnaJ domain Nif11 PF07862.11 GAP87113.1 - 0.084 13.2 2.7 5.2 7.4 0.0 3.7 4 0 0 4 4 4 0 Nif11 domain PNPase PF03726.14 GAP87113.1 - 0.34 11.5 9.8 8.5 6.9 0.2 4.1 4 0 0 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain NACHT_N PF17100.5 GAP87114.1 - 5.7e-78 261.8 4.6 1.2e-77 260.7 4.6 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 GAP87114.1 - 8e-71 232.2 48.2 4.4e-11 43.2 0.2 14.3 13 1 1 14 14 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP87114.1 - 1.4e-32 111.8 0.9 0.0044 17.3 0.0 11.1 2 2 10 12 12 12 8 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 GAP87114.1 - 4.9e-18 65.6 0.0 9.7e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF1513 PF07433.11 GAP87114.1 - 4.4e-08 32.6 1.2 1.4 7.9 0.0 6.9 2 2 6 8 8 8 2 Protein of unknown function (DUF1513) WD40_like PF17005.5 GAP87114.1 - 1.3e-07 31.3 0.6 0.21 10.9 0.0 4.4 3 1 1 4 4 4 3 WD40-like domain Atu4866 PF11512.8 GAP87114.1 - 3.1e-05 24.2 1.0 37 4.8 0.0 6.3 6 0 0 6 6 6 0 Agrobacterium tumefaciens protein Atu4866 DUF642 PF04862.12 GAP87114.1 - 0.00021 21.1 3.2 3 7.6 0.0 5.5 3 2 1 5 5 5 2 Protein of unknown function (DUF642) AAA_16 PF13191.6 GAP87114.1 - 0.0014 19.1 0.5 0.0051 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF4999 PF16390.5 GAP87114.1 - 0.026 14.8 0.3 82 3.5 0.0 4.5 1 1 4 5 5 5 0 Domain of unknown function AAA_22 PF13401.6 GAP87114.1 - 0.029 14.7 0.0 0.08 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAP87114.1 - 0.032 14.6 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.9 GAP87114.1 - 0.034 13.4 0.0 0.074 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GvpD PF07088.11 GAP87114.1 - 0.098 11.3 0.1 0.25 9.9 0.0 1.7 2 0 0 2 2 2 0 GvpD gas vesicle protein TFR_dimer PF04253.15 GAP87114.1 - 0.11 12.6 0.1 0.34 11.0 0.1 1.9 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain AAA_11 PF13086.6 GAP87114.1 - 1.2 8.9 0.0 1.2 8.9 0.0 2.9 2 1 0 2 2 1 0 AAA domain Stn1 PF10451.9 GAP87115.1 - 2.3e-14 53.0 0.1 1.1e-09 37.6 0.1 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 GAP87115.1 - 0.00011 22.1 0.4 0.12 12.3 0.1 2.4 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain Glyco_hydro81C PF17652.1 GAP87116.1 - 1.2e-160 534.6 2.8 1.5e-160 534.2 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 GAP87116.1 - 5e-115 384.1 1.2 7.5e-115 383.5 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Na_Ca_ex PF01699.24 GAP87117.1 - 2.4e-43 147.7 34.3 3.6e-23 82.2 13.7 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF2627 PF11118.8 GAP87117.1 - 0.32 11.6 6.4 1.3 9.6 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2627) Glyoxalase PF00903.25 GAP87118.1 - 7.6e-41 139.3 0.1 4.1e-20 72.3 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 GAP87118.1 - 4.9e-15 55.8 0.2 2.9e-05 24.3 0.0 4.3 2 2 2 4 4 4 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GAP87118.1 - 2.2e-08 34.9 0.0 0.017 15.9 0.0 3.3 2 2 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 GAP87118.1 - 4.3e-06 26.9 0.0 0.0034 17.5 0.0 2.7 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 GAP87118.1 - 0.0035 17.3 0.2 2.4 8.1 0.0 3.8 4 0 0 4 4 4 1 Glyoxalase-like domain MoaF PF10703.9 GAP87118.1 - 0.031 14.2 0.0 5 7.1 0.0 2.6 2 0 0 2 2 2 0 MoaF N-terminal domain CppA_N PF14506.6 GAP87118.1 - 0.052 13.6 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal 2-Hacid_dh_C PF02826.19 GAP87119.1 - 4.4e-52 176.0 0.0 7.5e-52 175.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP87119.1 - 1e-35 122.3 0.4 1.8e-35 121.5 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MFS_1 PF07690.16 GAP87120.1 - 6e-32 110.9 28.8 3.2e-21 75.7 16.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAP87120.1 - 1.6e-12 46.7 13.0 9.8e-07 27.7 1.3 3.2 3 0 0 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 GAP87120.1 - 3.9e-08 32.6 10.5 8.2e-05 21.6 1.1 2.1 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 GAP87120.1 - 3.3 6.4 19.5 1.1 8.0 8.4 2.6 2 1 0 2 2 2 0 Sugar (and other) transporter OATP PF03137.20 GAP87120.1 - 6.4 4.9 10.6 8.4 4.5 0.5 3.8 2 1 3 5 5 5 0 Organic Anion Transporter Polypeptide (OATP) family DUF4493 PF14900.6 GAP87121.1 - 0.014 15.3 0.5 0.014 15.3 0.5 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4493) Toxin_11 PF07473.11 GAP87122.1 - 0.0021 18.1 1.2 0.0045 17.0 1.2 1.6 1 0 0 1 1 1 1 Spasmodic peptide gm9a; conotoxin from Conus species SLR1-BP PF07333.12 GAP87122.1 - 0.0025 18.2 2.9 0.0045 17.4 2.9 1.4 1 0 0 1 1 1 1 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) TcA_TcB_BD PF18276.1 GAP87123.1 - 3.9e-50 170.6 1.2 4.5e-45 153.9 0.9 2.3 2 0 0 2 2 2 2 Tc toxin complex TcA C-terminal TcB-binding domain Neuraminidase PF18413.1 GAP87123.1 - 6.4e-35 120.3 1.4 1.3e-34 119.3 1.4 1.5 1 0 0 1 1 1 1 Neuraminidase-like domain VRP1 PF03538.14 GAP87123.1 - 2.3e-05 23.9 0.0 4.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Salmonella virulence plasmid 28.1kDa A protein PA14 PF07691.12 GAP87123.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 PA14 domain DUF3439 PF11921.8 GAP87124.1 - 0.36 10.8 3.2 0.73 9.8 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 GAP87124.1 - 3.4 5.5 7.0 4.7 5.1 7.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HSP70 PF00012.20 GAP87125.1 - 1.2e-10 40.3 0.2 3.5e-09 35.4 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein Thaumatin PF00314.17 GAP87126.1 - 5.8e-20 71.9 1.0 7.3e-20 71.5 1.0 1.1 1 0 0 1 1 1 1 Thaumatin family Thaumatin PF00314.17 GAP87127.1 - 1e-26 93.9 0.1 1.3e-26 93.6 0.1 1.1 1 0 0 1 1 1 1 Thaumatin family Ank_3 PF13606.6 GAP87128.1 - 4.2e-08 32.8 0.1 0.014 15.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 GAP87128.1 - 8e-07 29.6 0.0 1.7e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP87128.1 - 3.6e-06 27.4 0.0 6.6e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAP87128.1 - 0.00061 20.1 0.0 0.6 10.6 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAP87128.1 - 0.017 15.4 0.3 3.3 8.1 0.1 3.4 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Gar1 PF04410.14 GAP87128.1 - 0.32 10.8 2.9 0.49 10.1 2.9 1.3 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region TFIIS_C PF01096.18 GAP87129.1 - 8.1e-20 70.4 2.7 8.1e-20 70.4 2.7 2.9 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 GAP87129.1 - 1.3e-08 34.5 1.5 1.3e-07 31.4 0.3 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 GAP87129.1 - 0.0029 17.8 8.5 0.38 11.0 2.1 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 GAP87129.1 - 0.005 16.8 7.4 0.22 11.5 1.2 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Elf1 PF05129.13 GAP87129.1 - 0.013 15.5 3.8 0.14 12.2 0.2 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 GAP87129.1 - 0.015 15.2 6.3 1.6 8.8 0.7 3.3 3 1 0 3 3 3 0 zinc-ribbon domain DUF2387 PF09526.10 GAP87129.1 - 0.028 14.6 5.1 0.04 14.1 0.5 2.2 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Nudix_N_2 PF14803.6 GAP87129.1 - 0.029 14.3 5.9 0.04 13.9 1.8 2.3 2 0 0 2 2 2 0 Nudix N-terminal Glyco_hydro_49N PF17433.2 GAP87129.1 - 0.044 13.4 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain Desulfoferrod_N PF06397.12 GAP87129.1 - 0.097 12.3 1.3 0.81 9.4 0.1 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Zn_ribbon_recom PF13408.6 GAP87129.1 - 0.2 12.2 4.3 0.33 11.5 0.8 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_S27e PF01667.17 GAP87129.1 - 0.36 10.6 3.9 1.7 8.4 0.3 2.8 3 0 0 3 3 3 0 Ribosomal protein S27 UPF0547 PF10571.9 GAP87129.1 - 1.2 9.3 0.1 1.2 9.3 0.1 3.3 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-RING_12 PF17976.1 GAP87129.1 - 1.8 8.9 6.3 0.77 10.1 0.2 2.6 2 2 0 2 2 2 0 RING/Ubox like zinc-binding domain CFEM PF05730.11 GAP87130.1 - 1.4e-10 41.1 8.7 2.1e-10 40.5 8.7 1.2 1 0 0 1 1 1 1 CFEM domain Mito_carr PF00153.27 GAP87130.1 - 1 9.3 0.1 1 9.3 0.1 2.7 4 0 0 4 4 4 0 Mitochondrial carrier protein FAD_binding_4 PF01565.23 GAP87131.1 - 3.4e-17 62.5 2.2 5.2e-17 61.9 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 GAP87131.1 - 0.0014 18.5 0.8 0.18 11.6 0.7 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase AlkA_N PF06029.11 GAP87131.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 AlkA N-terminal domain Atg29_N PF18388.1 GAP87133.1 - 1.8e-26 91.7 1.2 1.8e-26 91.7 1.2 1.9 2 0 0 2 2 2 1 Atg29 N-terminal domain WD40 PF00400.32 GAP87136.1 - 4.1e-12 46.4 1.0 0.0027 18.5 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.6 GAP87136.1 - 0.00042 20.7 0.0 3 8.4 0.0 4.0 4 0 0 4 4 4 2 PQQ-like domain PQQ_2 PF13360.6 GAP87136.1 - 0.032 13.8 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 PQQ-like domain Ras PF00071.22 GAP87137.1 - 4.7e-51 172.6 0.0 5.5e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP87137.1 - 6.7e-17 61.8 0.0 9.6e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP87137.1 - 3.8e-09 36.2 0.0 5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAP87137.1 - 9.5e-06 25.6 0.0 0.085 12.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAP87137.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAP87137.1 - 0.0017 18.0 0.3 0.015 14.9 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 GAP87137.1 - 0.026 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 GAP87137.1 - 0.03 14.5 1.3 0.04 14.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAP87137.1 - 0.033 14.5 0.1 0.31 11.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 GAP87137.1 - 0.057 12.8 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RRM_1 PF00076.22 GAP87139.1 - 6.6e-22 77.1 0.0 1.4e-12 47.3 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAP87139.1 - 0.029 14.2 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 GAP87139.1 - 0.095 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Methyltransf_23 PF13489.6 GAP87141.1 - 8.5e-22 77.7 0.0 2e-21 76.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP87141.1 - 7.7e-14 52.2 0.0 1.7e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP87141.1 - 1.7e-13 50.7 0.0 4.8e-13 49.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP87141.1 - 3.8e-13 49.9 0.0 8e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP87141.1 - 2.3e-10 41.1 0.0 8.2e-09 36.1 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 GAP87141.1 - 0.0016 18.0 0.0 0.0077 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 GAP87141.1 - 0.0039 17.3 0.0 0.0065 16.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 GAP87141.1 - 0.006 16.1 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase GidB PF02527.15 GAP87141.1 - 0.014 14.7 0.0 0.04 13.2 0.0 1.7 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G CheR PF01739.18 GAP87141.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PrmA PF06325.13 GAP87141.1 - 0.029 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 GAP87141.1 - 0.043 13.1 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain PCMT PF01135.19 GAP87141.1 - 0.048 13.4 0.0 0.51 10.1 0.0 2.0 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 GAP87141.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_29 PF03141.16 GAP87141.1 - 0.17 10.4 0.0 1.1 7.7 0.0 1.9 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Zn_clus PF00172.18 GAP87142.1 - 0.0025 17.9 9.5 0.004 17.3 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HrpA_pilin PF09589.10 GAP87142.1 - 0.09 13.5 1.0 0.22 12.3 1.0 1.5 1 0 0 1 1 1 0 HrpA pilus formation protein DUF997 PF06196.12 GAP87144.1 - 0.039 13.9 0.2 0.075 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF997) EGF_2 PF07974.13 GAP87144.1 - 0.75 10.2 10.4 1.3 9.4 10.4 1.4 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 GAP87144.1 - 0.9 9.9 5.0 1.7 9.0 5.0 1.5 1 0 0 1 1 1 0 EGF-like domain HNH_2 PF13391.6 GAP87145.1 - 1.4e-08 34.7 0.1 4.9e-08 33.0 0.1 2.0 1 0 0 1 1 1 1 HNH endonuclease HET PF06985.11 GAP87146.1 - 1.6e-29 103.2 2.3 5.1e-29 101.5 2.3 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3490 PF11995.8 GAP87146.1 - 0.086 12.7 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3490) NUDIX PF00293.28 GAP87147.1 - 0.0001 22.3 1.3 0.00082 19.4 0.4 2.6 2 1 0 2 2 2 1 NUDIX domain ThiF PF00899.21 GAP87148.1 - 4.7e-12 45.8 1.5 8.4e-12 45.0 1.5 1.3 1 0 0 1 1 1 1 ThiF family Ldh_1_N PF00056.23 GAP87148.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAP87148.1 - 0.031 14.5 0.2 0.057 13.7 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DinB_2 PF12867.7 GAP87148.1 - 0.093 13.2 0.0 1.6 9.2 0.0 2.3 1 1 0 1 1 1 0 DinB superfamily ApbA PF02558.16 GAP87148.1 - 0.1 12.3 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 GAP87148.1 - 0.27 11.5 2.5 0.5 10.6 0.1 2.5 3 1 0 3 3 3 0 TrkA-N domain GIDA PF01134.22 GAP87148.1 - 0.65 9.0 2.4 1.1 8.3 0.5 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Carb_anhydrase PF00194.21 GAP87149.1 - 4.6e-33 114.8 0.0 6e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Lipase3_N PF03893.16 GAP87150.1 - 0.00027 20.9 0.2 0.0058 16.6 0.1 2.4 1 1 1 2 2 2 1 Lipase 3 N-terminal region Gly_rich PF12810.7 GAP87150.1 - 0.011 15.7 0.7 0.023 14.6 0.7 1.5 1 0 0 1 1 1 0 Glycine rich protein F-box-like PF12937.7 GAP87150.1 - 0.095 12.6 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 F-box-like Endonuc-BglII PF09195.11 GAP87150.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease BglII MYO10_CC PF16735.5 GAP87150.1 - 0.2 11.8 0.0 0.58 10.3 0.0 1.7 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain PAP_assoc PF03828.19 GAP87151.1 - 1.5e-16 60.3 0.2 4.2e-16 58.9 0.2 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAP87151.1 - 5.7e-06 26.5 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 GAP87151.1 - 0.0068 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Phage_TAC_5 PF08890.11 GAP87151.1 - 0.34 10.9 1.4 5.1 7.1 1.2 2.2 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC AhpC-TSA_2 PF13911.6 GAP87152.1 - 5.2e-07 29.8 0.3 1.3e-06 28.5 0.3 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 GAP87152.1 - 3.9e-06 26.8 0.0 6.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAP87152.1 - 0.0035 17.1 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin CALM_bind PF16025.5 GAP87153.1 - 0.042 14.3 4.0 0.085 13.3 4.0 1.5 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding BORCS7 PF16088.5 GAP87153.1 - 0.13 12.5 0.2 0.28 11.5 0.2 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 SLC35F PF06027.12 GAP87155.1 - 1e-93 314.2 23.7 1.2e-93 313.9 23.7 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 GAP87155.1 - 4.9e-08 32.3 4.2 7.6e-08 31.7 4.2 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 GAP87155.1 - 9.7e-06 25.8 39.9 0.00015 22.0 17.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAP87155.1 - 0.0013 18.1 3.9 0.0013 18.1 3.9 1.7 2 0 0 2 2 2 1 Triose-phosphate Transporter family FUSC-like PF12805.7 GAP87155.1 - 0.65 9.0 8.9 0.085 11.9 2.6 2.5 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS SIR2 PF02146.17 GAP87157.1 - 2.1e-53 180.9 0.0 2.7e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 GAP87157.1 - 0.022 14.5 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Mem_trans PF03547.18 GAP87158.1 - 3.4e-54 183.7 3.4 1.4e-53 181.7 3.4 1.7 1 1 0 1 1 1 1 Membrane transport protein Phage_holin_1 PF04531.13 GAP87158.1 - 0.013 16.0 0.1 0.054 14.0 0.1 2.1 1 0 0 1 1 1 0 Bacteriophage holin Pkinase PF00069.25 GAP87159.1 - 1.9e-51 175.0 0.0 2.2e-48 164.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87159.1 - 3.8e-31 108.3 0.0 6.6e-30 104.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAP87159.1 - 0.00011 21.2 0.0 0.00015 20.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAP87159.1 - 0.00076 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 GAP87159.1 - 0.0023 17.1 0.1 0.004 16.2 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 GAP87159.1 - 0.0058 15.5 0.0 0.008 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 GAP87159.1 - 0.29 10.1 0.0 0.44 9.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SUR7 PF06687.12 GAP87160.1 - 3e-36 125.0 4.0 3.7e-36 124.7 4.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF973 PF06157.11 GAP87160.1 - 0.031 13.3 0.3 0.047 12.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Tim17 PF02466.19 GAP87160.1 - 0.1 12.9 4.6 0.092 13.1 2.3 1.9 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Amastin PF07344.11 GAP87160.1 - 0.2 11.5 15.6 0.036 13.9 11.7 1.6 2 0 0 2 2 2 0 Amastin surface glycoprotein DNA_methylase PF00145.17 GAP87161.1 - 7.9e-35 120.8 0.0 5.7e-22 78.5 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase MFS_1 PF07690.16 GAP87162.1 - 6.4e-33 114.1 57.0 3.8e-29 101.7 40.7 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP87162.1 - 1.8e-10 40.3 12.9 1.8e-10 40.3 12.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAP87162.1 - 2.9e-10 39.2 10.9 2.9e-10 39.2 10.9 2.2 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4079 PF13301.6 GAP87162.1 - 0.051 13.7 0.9 1 9.5 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF3328 PF11807.8 GAP87163.1 - 3.7e-17 62.9 0.0 4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 GAP87164.1 - 5.6e-28 98.2 8.6 2.2e-27 96.3 6.8 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 GAP87165.1 - 1.7e-26 93.4 0.3 2.2e-26 93.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ig_J_chain PF15097.6 GAP87166.1 - 0.06 13.2 0.3 52 3.7 0.0 3.5 1 1 3 4 4 4 0 Immunoglobulin J chain HisKA_3 PF07730.13 GAP87166.1 - 0.19 12.3 0.1 4.1e+02 1.6 0.0 3.8 4 0 0 4 4 4 0 Histidine kinase DUF3755 PF12579.8 GAP87166.1 - 2.8 7.7 6.5 49 3.7 0.1 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3755) DUF3328 PF11807.8 GAP87167.1 - 1.1e-26 93.9 0.4 1.6e-26 93.5 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ank_2 PF12796.7 GAP87168.1 - 5.5e-127 414.6 20.7 1e-15 58.1 0.2 15.4 6 4 9 16 16 16 15 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP87168.1 - 4.5e-97 317.3 20.4 1.1e-09 38.6 0.2 19.7 13 7 8 21 21 21 17 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP87168.1 - 1.4e-74 245.1 33.0 6e-09 36.0 0.2 20.7 14 4 7 21 21 21 17 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP87168.1 - 5.3e-72 229.2 29.4 0.0041 17.5 0.0 26.3 31 0 0 31 31 31 17 Ankyrin repeat Ank PF00023.30 GAP87168.1 - 7.7e-68 222.2 49.9 7.1e-05 23.1 0.2 26.0 26 2 0 26 26 26 16 Ankyrin repeat SPRY PF00622.28 GAP87168.1 - 3.1e-15 56.4 0.8 8.8e-15 54.9 0.5 2.0 2 0 0 2 2 2 1 SPRY domain DUF1182 PF06681.13 GAP87168.1 - 0.15 11.7 0.4 0.29 10.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) Pectinesterase PF01095.19 GAP87169.1 - 1.1e-24 86.7 0.3 2.7e-20 72.3 0.2 2.1 2 0 0 2 2 2 2 Pectinesterase Glyco_hydro_28 PF00295.17 GAP87170.1 - 3.2e-50 171.0 10.1 5e-50 170.4 10.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pirin PF02678.16 GAP87171.1 - 1.4e-23 82.9 0.9 4.5e-23 81.3 0.9 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 GAP87171.1 - 0.00022 20.9 3.3 0.022 14.4 0.4 3.4 2 1 0 2 2 2 2 Cupin domain HhH-GPD PF00730.25 GAP87172.1 - 1.6e-07 31.7 0.0 9.9e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein SEN1_N PF12726.7 GAP87173.1 - 1.9e-182 608.4 4.4 2.4e-182 608.0 4.4 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 GAP87173.1 - 1.2e-72 244.9 0.4 1.2e-72 244.9 0.4 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 GAP87173.1 - 3.9e-62 209.4 0.0 4.8e-61 205.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 GAP87173.1 - 1.6e-09 37.7 0.3 6.8e-06 25.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAP87173.1 - 6.6e-09 36.3 0.2 4.1e-08 33.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 GAP87173.1 - 6.1e-06 26.1 0.7 0.0056 16.4 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 GAP87173.1 - 4.1e-05 23.3 1.2 0.03 13.9 0.0 3.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain MFS_1 PF07690.16 GAP87174.1 - 1.4e-16 60.4 31.3 5.6e-16 58.4 26.9 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy PF03171.20 GAP87175.1 - 6e-15 55.6 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 GAP87175.1 - 1.8e-10 41.6 0.0 3.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal APH PF01636.23 GAP87176.1 - 5e-11 43.0 0.0 1.1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAP87176.1 - 2e-08 33.9 0.1 9.2e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase Choline_kinase PF01633.20 GAP87176.1 - 0.011 15.4 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase FAD_binding_3 PF01494.19 GAP87177.1 - 2.6e-23 82.8 0.0 4.9e-23 81.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 GAP87177.1 - 0.014 14.4 0.0 1.4 7.8 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAP87177.1 - 0.017 15.6 0.1 0.05 14.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP87177.1 - 0.024 13.9 0.1 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP87177.1 - 0.11 12.8 0.0 0.4 11.0 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HET PF06985.11 GAP87180.1 - 7.4e-31 107.5 0.0 1.3e-30 106.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VSP PF03302.13 GAP87181.1 - 0.0023 16.8 0.8 0.0034 16.3 0.8 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein PCI PF01399.27 GAP87182.1 - 3.4e-21 75.7 0.0 1.1e-20 74.1 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 GAP87182.1 - 1.6e-16 60.1 2.7 3.8e-16 58.9 2.7 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF3781 PF12636.7 GAP87182.1 - 0.1 12.5 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) NIPSNAP PF07978.13 GAP87183.1 - 1.3e-41 141.0 0.7 1.6e-30 105.3 0.2 2.5 2 0 0 2 2 2 2 NIPSNAP Rogdi_lz PF10259.9 GAP87184.1 - 3.9e-90 301.9 0.0 4.6e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.8 GAP87185.1 - 9.7e-22 77.4 1.1 1.7e-21 76.6 1.1 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 GAP87185.1 - 5.3e-08 32.6 0.0 1e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 Alba DAO PF01266.24 GAP87186.1 - 7.3e-31 108.0 0.1 1.1e-30 107.5 0.1 1.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 GAP87186.1 - 1.7e-06 27.4 0.0 2.1e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 GAP87186.1 - 1.9e-05 24.7 0.0 0.093 12.7 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAP87186.1 - 5.6e-05 22.5 0.0 0.00047 19.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP87186.1 - 0.0028 17.8 0.0 0.0079 16.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAP87186.1 - 0.0068 15.5 0.0 0.84 8.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.14 GAP87186.1 - 0.022 13.6 0.0 2.2 7.0 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GMC_oxred_N PF00732.19 GAP87186.1 - 0.08 12.3 0.0 8.2 5.7 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase TrkA_N PF02254.18 GAP87186.1 - 0.1 12.9 0.0 0.3 11.4 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain GMC_oxred_N PF00732.19 GAP87187.1 - 8e-27 94.4 0.0 1.3e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP87187.1 - 1.7e-22 80.5 0.2 3.3e-22 79.6 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAP87187.1 - 1.3e-07 31.1 0.1 0.0014 17.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAP87187.1 - 0.00025 21.2 0.0 0.00071 19.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP87187.1 - 0.00045 19.5 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP87187.1 - 0.006 16.2 2.4 0.058 13.0 2.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAP87187.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAP87187.1 - 0.043 12.5 0.0 0.11 11.1 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 GAP87187.1 - 0.053 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAP87187.1 - 0.18 11.0 0.3 0.33 10.1 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CRAL_TRIO PF00650.20 GAP87188.1 - 3.2e-37 127.7 0.0 4.9e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAP87188.1 - 2e-09 37.5 0.0 5.9e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAP87188.1 - 5.5e-05 23.3 0.0 7.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain BNIP3 PF06553.12 GAP87188.1 - 0.015 14.9 1.5 0.023 14.4 1.5 1.2 1 0 0 1 1 1 0 BNIP3 Herpes_pp85 PF04637.12 GAP87188.1 - 0.33 9.3 0.6 0.47 8.8 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SR-25 PF10500.9 GAP87188.1 - 0.5 10.0 3.4 0.78 9.3 3.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FMO-like PF00743.19 GAP87189.1 - 9.9e-11 40.7 0.1 3.2e-09 35.8 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 GAP87189.1 - 5.1e-10 39.0 0.0 2.3e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 GAP87189.1 - 3.9e-09 36.2 0.0 1e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP87189.1 - 5.8e-09 36.1 0.4 6.1e-08 32.8 0.0 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP87189.1 - 1.7e-05 24.6 4.1 0.0001 22.0 0.4 3.2 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP87189.1 - 0.00012 21.4 0.1 0.00057 19.2 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP87189.1 - 0.00027 20.2 0.1 0.0075 15.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 GAP87189.1 - 0.0022 17.1 1.3 0.0085 15.2 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 GAP87189.1 - 0.003 16.9 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 GAP87189.1 - 0.006 16.0 0.2 0.013 14.9 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAP87189.1 - 0.016 14.3 1.0 0.14 11.2 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAP87189.1 - 0.082 13.5 0.1 13 6.4 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP87189.1 - 0.16 11.1 1.0 0.29 10.2 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 GAP87189.1 - 1.7 8.6 4.7 3.4 7.6 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Abhydrolase_3 PF07859.13 GAP87190.1 - 1.1e-28 100.6 0.0 1.4e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP87190.1 - 5.6e-12 45.2 0.0 9.8e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 GAP87190.1 - 0.00075 18.5 0.0 0.0043 16.0 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family adh_short PF00106.25 GAP87191.1 - 1.5e-41 142.0 0.0 2.2e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87191.1 - 2.6e-28 99.2 0.0 3.6e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87191.1 - 2.9e-09 37.1 0.9 9.2e-09 35.5 0.9 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP87191.1 - 1.3e-05 24.8 0.0 2.6e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 GAP87191.1 - 0.00039 19.8 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAP87191.1 - 0.00051 19.1 0.0 0.00067 18.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAP87191.1 - 0.00089 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 GAP87191.1 - 0.01 15.2 0.2 0.019 14.3 0.2 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Zn_clus PF00172.18 GAP87192.1 - 2.5e-09 37.1 9.7 6.7e-09 35.7 9.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAP87192.1 - 0.00084 18.3 0.2 0.0012 17.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 GAP87193.1 - 3.5e-73 246.9 0.0 4.5e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.6 GAP87194.1 - 2.3e-08 34.0 0.0 3.6e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP87194.1 - 4.1e-07 30.6 0.0 8.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP87194.1 - 1.6e-06 28.8 0.0 2.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP87194.1 - 2.4e-05 24.3 0.0 3.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP87194.1 - 0.00088 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 GAP87194.1 - 0.0012 19.4 0.0 0.0022 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 GAP87194.1 - 0.0028 17.2 0.0 0.012 15.2 0.0 1.8 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain CpXC PF14353.6 GAP87194.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 CpXC protein Methyltransf_4 PF02390.17 GAP87194.1 - 0.19 11.2 0.0 0.87 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Glyco_hydro_31 PF01055.26 GAP87195.1 - 2.1e-123 412.8 1.6 1e-84 285.3 0.4 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAP87195.1 - 1.2e-33 115.8 0.1 2e-33 115.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 GAP87195.1 - 7.4e-12 45.4 0.3 4.5e-11 42.9 0.3 2.4 1 0 0 1 1 1 1 Galactose mutarotase-like Semialdhyde_dh PF01118.24 GAP87196.1 - 3.6e-28 98.4 0.0 9.1e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 GAP87196.1 - 0.0084 16.2 0.0 0.028 14.5 0.0 2.0 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DASH_Spc19 PF08287.11 GAP87198.1 - 3.3e-45 153.8 0.8 4.8e-45 153.3 0.8 1.2 1 0 0 1 1 1 1 Spc19 COG5 PF10392.9 GAP87198.1 - 0.0038 17.4 1.0 1.9 8.7 0.1 2.6 2 1 1 3 3 3 2 Golgi transport complex subunit 5 SH3_1 PF00018.28 GAP87199.1 - 9e-09 34.8 0.1 1.7e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAP87199.1 - 1.6e-06 27.7 0.0 2.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAP87199.1 - 6.9e-06 25.8 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Dynactin_p22 PF07426.11 GAP87200.1 - 2.9e-07 30.5 0.0 4.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Aa_trans PF01490.18 GAP87201.1 - 1.1e-93 314.2 16.0 1.4e-93 313.9 16.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 GAP87201.1 - 0.00013 21.2 18.9 0.00024 20.2 18.9 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Abhydrolase_9_N PF15420.6 GAP87201.1 - 0.008 16.2 1.6 0.008 16.2 1.6 2.6 3 0 0 3 3 3 1 Alpha/beta-hydrolase family N-terminus Lyase_1 PF00206.20 GAP87202.1 - 9.1e-110 366.9 0.0 1.2e-109 366.5 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 GAP87202.1 - 1.8e-19 69.9 0.0 5e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus SR-25 PF10500.9 GAP87202.1 - 4.2 6.9 7.9 6.8 6.2 7.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.32 GAP87203.1 - 2e-16 60.1 11.3 0.00061 20.5 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP87203.1 - 5.5e-08 33.0 0.0 0.0052 17.1 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP87203.1 - 0.043 12.8 0.1 9.7 5.0 0.0 3.3 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 GAP87203.1 - 0.055 12.8 0.1 1.4 8.2 0.0 2.8 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Phosphonate-bd PF12974.7 GAP87204.1 - 3.6e-12 46.4 0.0 5e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein AMP-binding PF00501.28 GAP87205.1 - 3.1e-84 283.0 0.0 4.1e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP87205.1 - 2.9e-16 60.2 1.4 1.3e-15 58.1 1.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribosomal_S14 PF00253.21 GAP87207.1 - 2.1e-20 72.2 1.0 4e-20 71.3 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e GGACT PF06094.12 GAP87210.1 - 3.3e-06 27.7 0.1 4.5e-06 27.3 0.1 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like gp37_C PF12604.8 GAP87210.1 - 0.0014 18.3 0.0 0.0051 16.5 0.0 1.8 2 1 0 2 2 2 1 Tail fibre protein gp37 C terminal AIG2_2 PF13772.6 GAP87210.1 - 0.035 14.5 0.0 0.087 13.2 0.0 1.9 1 1 0 1 1 1 0 AIG2-like family GGACT PF06094.12 GAP87211.1 - 1.6e-08 35.2 0.0 6.4e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 GAP87211.1 - 3.7e-07 30.4 0.0 2.2e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family Pro-rich_19 PF15455.6 GAP87211.1 - 0.14 11.3 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Proline-rich 19 TraL PF07178.11 GAP87212.1 - 0.26 11.8 0.9 0.48 10.9 0.9 1.4 1 0 0 1 1 1 0 TraL protein Erf4 PF10256.9 GAP87213.1 - 0.031 14.4 0.0 0.098 12.8 0.0 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Amnionless PF14828.6 GAP87214.1 - 0.0033 16.3 8.1 0.0037 16.1 8.1 1.1 1 0 0 1 1 1 1 Amnionless MMPL PF03176.15 GAP87214.1 - 0.0081 15.1 22.4 0.01 14.8 22.4 1.1 1 0 0 1 1 1 1 MMPL family DUF2207 PF09972.9 GAP87214.1 - 0.025 13.4 3.2 0.025 13.4 3.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Gly-zipper_OmpA PF13436.6 GAP87214.1 - 0.97 9.3 7.0 4 7.3 7.0 1.9 1 1 0 1 1 1 0 Glycine-zipper domain DUF1129 PF06570.11 GAP87214.1 - 1.2 8.6 13.3 1.5 8.3 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) TraG_N PF07916.11 GAP87214.1 - 1.8 7.3 20.3 2 7.1 20.3 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region RhoGAP PF00620.27 GAP87215.1 - 6.9e-50 168.8 0.0 1.8e-49 167.5 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 GAP87215.1 - 1.2e-14 54.4 0.2 1.2e-14 54.4 0.2 2.2 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain UPF0139 PF03669.13 GAP87216.1 - 6.2e-10 38.8 0.0 7.8e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF3325 PF11804.8 GAP87216.1 - 0.085 13.0 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) Med12 PF09497.10 GAP87217.1 - 1.5e-28 98.9 0.3 5.9e-28 97.0 0.3 2.2 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 PQ-loop PF04193.14 GAP87218.1 - 2.9e-36 123.0 15.0 7.3e-19 67.3 1.3 2.8 3 0 0 3 3 3 2 PQ loop repeat S1-P1_nuclease PF02265.16 GAP87219.1 - 1.6e-74 250.9 0.3 1.8e-74 250.8 0.3 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF1691 PF07950.11 GAP87219.1 - 0.047 14.4 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Kelch_4 PF13418.6 GAP87221.1 - 2.5e-34 117.0 8.0 1.8e-06 27.8 0.4 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 GAP87221.1 - 1.4e-31 107.9 6.9 3.7e-09 36.4 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 GAP87221.1 - 2.4e-31 107.0 6.2 4.4e-11 42.7 0.5 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_3 PF13415.6 GAP87221.1 - 2.8e-29 100.8 7.6 3.5e-08 33.5 0.1 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 GAP87221.1 - 5.7e-28 96.2 5.4 5.6e-11 41.8 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 GAP87221.1 - 2.1e-22 78.1 6.4 8.1e-08 31.9 0.3 6.6 6 0 0 6 6 6 5 Kelch motif RAG2 PF03089.14 GAP87221.1 - 0.05 12.6 0.1 1.2 8.0 0.0 3.1 4 0 0 4 4 4 0 Recombination activating protein 2 Raptor_N PF14538.6 GAP87222.1 - 1e-64 216.9 0.0 2.5e-64 215.6 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 GAP87222.1 - 2.3e-05 25.0 1.4 4.4 8.3 0.0 5.2 4 0 0 4 4 4 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 GAP87222.1 - 0.0015 18.6 0.1 2.1 8.4 0.1 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.6 GAP87222.1 - 0.0047 17.3 0.5 0.12 12.7 0.0 3.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 GAP87222.1 - 0.029 14.6 5.6 8 7.0 0.0 5.1 7 0 0 7 7 7 0 HEAT repeat Spt20 PF12090.8 GAP87222.1 - 0.28 10.8 16.7 0.51 9.9 16.7 1.4 1 0 0 1 1 1 0 Spt20 family Blt1 PF12754.7 GAP87222.1 - 0.77 10.1 2.4 1.7 8.9 2.4 1.5 1 0 0 1 1 1 0 Blt1 N-terminal domain TFIIA PF03153.13 GAP87222.1 - 2.6 7.9 28.9 0.16 12.0 23.6 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PA PF02225.22 GAP87223.1 - 0.31 11.1 3.9 0.55 10.3 1.5 2.2 2 0 0 2 2 2 0 PA domain K_channel_TID PF07941.11 GAP87223.1 - 5 7.7 11.7 14 6.3 8.2 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain CorA PF01544.18 GAP87224.1 - 4.2e-11 42.7 0.4 9.3e-11 41.6 0.1 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Big_9 PF17963.1 GAP87225.1 - 0.61 10.9 2.9 3.8 8.3 0.5 2.5 2 1 1 3 3 3 0 Bacterial Ig domain Hydrophobin_2 PF06766.11 GAP87227.1 - 3.1e-30 103.9 8.3 4.4e-30 103.4 8.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DJ-1_PfpI PF01965.24 GAP87228.1 - 2.3e-19 69.8 0.0 2.8e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF2953 PF11167.8 GAP87228.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) ApbA PF02558.16 GAP87229.1 - 1.1e-25 90.0 0.0 1.8e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 GAP87229.1 - 8.3e-23 80.9 0.0 1.3e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.11 GAP87230.1 - 2.6e-20 72.5 3.5 3.5e-20 72.1 3.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like PTPLA PF04387.14 GAP87231.1 - 5e-41 140.2 0.8 5e-41 140.2 0.8 1.6 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Rpr2 PF04032.16 GAP87233.1 - 8e-23 80.5 0.0 1.6e-22 79.6 0.0 1.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.29 GAP87234.1 - 9.3e-39 133.0 0.0 1.6e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP87234.1 - 7.7e-26 90.6 0.2 2.6e-24 85.7 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP87234.1 - 4.3e-08 33.3 0.0 1e-07 32.1 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAP87234.1 - 0.049 13.0 0.1 0.21 10.9 0.1 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF4844 PF16133.5 GAP87234.1 - 0.073 13.6 0.7 0.17 12.4 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Mg_trans_NIPA PF05653.14 GAP87235.1 - 9.8e-16 57.7 7.2 1.7e-15 56.9 7.2 1.3 1 1 0 1 1 1 1 Magnesium transporter NIPA PUNUT PF16913.5 GAP87235.1 - 0.00051 19.4 7.2 0.0017 17.7 7.2 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 GAP87235.1 - 0.00071 19.8 3.0 0.00071 19.8 3.0 3.5 2 2 1 3 3 3 1 EamA-like transporter family vATP-synt_E PF01991.18 GAP87236.1 - 6.1e-67 224.9 12.5 6.8e-67 224.7 12.5 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit VTC PF09359.10 GAP87236.1 - 0.02 14.3 1.4 0.023 14.1 1.4 1.1 1 0 0 1 1 1 0 VTC domain Methyltransf_7 PF03492.15 GAP87236.1 - 0.1 11.8 1.0 0.14 11.3 1.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase PhoLip_ATPase_C PF16212.5 GAP87238.1 - 2.5e-79 266.6 22.4 2.5e-79 266.6 22.4 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAP87238.1 - 1.7e-18 66.0 1.2 4.6e-18 64.7 1.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAP87238.1 - 6e-13 48.7 0.0 5.8e-12 45.5 0.0 2.6 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAP87238.1 - 1.8e-11 44.7 4.0 3.2e-07 30.9 1.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAP87238.1 - 0.0087 15.6 0.0 0.031 13.8 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAP87238.1 - 0.014 15.1 0.6 0.032 14.0 0.6 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldedh PF00171.22 GAP87239.1 - 3.8e-115 385.0 0.0 4.3e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MHYT PF03707.16 GAP87239.1 - 0.15 12.2 1.4 0.7 10.1 0.5 2.5 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat SMC_N PF02463.19 GAP87240.1 - 3e-25 89.0 0.0 5.4e-25 88.1 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 GAP87240.1 - 3.5e-10 40.1 0.1 4e-06 26.8 0.0 3.6 2 2 1 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 GAP87240.1 - 2.1e-08 34.9 67.2 7.8e-08 33.0 36.7 6.6 1 1 1 2 2 2 1 AAA domain AAA_21 PF13304.6 GAP87240.1 - 7.2e-06 26.0 0.8 0.031 14.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAP87240.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 GAP87240.1 - 0.045 14.2 0.0 0.19 12.2 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 GAP87240.1 - 0.53 9.8 0.0 0.53 9.8 0.0 3.9 6 1 0 6 6 6 0 AAA domain Fez1 PF06818.15 GAP87240.1 - 7.5 6.9 65.0 3.1 8.2 5.6 5.1 2 2 2 4 4 4 0 Fez1 DUF3287 PF11690.8 GAP87240.1 - 8.2 6.2 8.7 1.7 8.4 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) Pkinase PF00069.25 GAP87241.1 - 2.5e-65 220.5 0.0 3.7e-64 216.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 GAP87241.1 - 2.6e-42 143.3 0.0 5.2e-42 142.3 0.0 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 GAP87241.1 - 1.6e-33 116.1 0.0 1.7e-30 106.1 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAP87241.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAP87241.1 - 0.00064 18.8 0.9 0.002 17.1 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 GAP87241.1 - 0.016 15.1 0.0 0.056 13.4 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP87241.1 - 0.039 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Malate_synthase PF01274.22 GAP87242.1 - 1.1e-230 766.4 0.0 1.3e-230 766.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Clr5 PF14420.6 GAP87244.1 - 1.8e-23 82.5 0.7 2.4e-23 82.1 0.7 1.2 1 0 0 1 1 1 1 Clr5 domain Menin PF05053.13 GAP87245.1 - 2.6 6.3 4.9 4 5.7 4.9 1.2 1 0 0 1 1 1 0 Menin Robl_LC7 PF03259.17 GAP87246.1 - 8.6e-08 31.9 0.0 2.8e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.8 GAP87247.1 - 8.7e-22 77.6 0.0 2.5e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.6 GAP87247.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats Cyclin PF08613.11 GAP87248.1 - 4.2e-06 27.2 1.3 4.2e-06 27.2 1.3 2.6 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 GAP87248.1 - 0.00039 20.2 0.1 0.00078 19.2 0.1 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain AAA PF00004.29 GAP87251.1 - 2.9e-18 66.6 0.0 7.8e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_5 PF13857.6 GAP87251.1 - 2.9e-07 30.6 0.0 0.00037 20.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_33 PF13671.6 GAP87251.1 - 3.5e-07 30.5 0.1 8.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.7 GAP87251.1 - 9.5e-07 29.3 0.0 4.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP87251.1 - 9.8e-06 26.0 0.0 4.2e-05 24.0 0.0 2.2 2 0 0 2 2 1 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 GAP87251.1 - 6e-05 23.3 0.2 0.0043 17.3 0.1 2.9 1 1 1 2 2 2 1 AAA domain Ank_3 PF13606.6 GAP87251.1 - 0.00072 19.8 0.0 2.8 8.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 GAP87251.1 - 0.001 19.4 0.0 6.4 7.4 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat AAA_5 PF07728.14 GAP87251.1 - 0.0018 18.2 0.0 0.0042 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAP87251.1 - 0.0044 17.6 0.2 0.023 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAP87251.1 - 0.015 15.7 0.2 0.058 13.8 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 GAP87251.1 - 0.032 14.0 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 GAP87251.1 - 0.08 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAP87251.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ATPase PF06745.13 GAP87251.1 - 0.16 11.3 0.9 1.2 8.4 0.2 2.2 1 1 0 2 2 2 0 KaiC HET PF06985.11 GAP87252.1 - 2.8e-35 121.8 0.3 5.9e-35 120.8 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NAD_binding_2 PF03446.15 GAP87253.1 - 3e-37 128.2 0.8 4.5e-37 127.6 0.8 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAP87253.1 - 9.2e-22 77.6 0.1 1.4e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 GAP87253.1 - 1e-05 24.6 0.1 1.7e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 GAP87253.1 - 1.2e-05 25.8 0.0 2.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 GAP87253.1 - 0.0011 19.1 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 GAP87253.1 - 0.0038 16.8 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 GAP87253.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 GAP87253.1 - 0.015 16.1 0.0 0.041 14.7 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 GAP87253.1 - 0.021 15.1 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HET PF06985.11 GAP87254.1 - 2.7e-34 118.6 0.6 4.3e-34 118.0 0.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 GAP87255.1 - 3.5e-68 229.8 0.0 5.8e-68 229.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87255.1 - 1.1e-50 172.3 0.0 1.9e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP87255.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 GAP87255.1 - 0.0045 16.0 0.0 1.4 7.8 0.0 2.9 3 1 0 3 3 3 2 Haspin like kinase domain Kinase-like PF14531.6 GAP87255.1 - 0.038 13.3 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Kinase-like K_channel_TID PF07941.11 GAP87256.1 - 0.036 14.5 2.5 0.036 14.5 2.5 4.3 4 0 0 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain Iso_dh PF00180.20 GAP87257.1 - 9.1e-81 271.7 0.0 1.1e-80 271.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Copine PF07002.16 GAP87257.1 - 0.12 11.8 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Copine Acetyltransf_3 PF13302.7 GAP87258.1 - 9.6e-20 71.7 0.1 1.2e-19 71.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP87258.1 - 0.0034 17.6 0.2 0.52 10.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.10 GAP87258.1 - 0.0093 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 GAP87258.1 - 0.033 13.9 2.8 0.74 9.5 0.0 2.7 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain SH3_9 PF14604.6 GAP87259.1 - 7.8e-06 25.7 0.2 2e-05 24.4 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAP87259.1 - 0.0082 15.8 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAP87259.1 - 0.26 10.9 0.9 0.62 9.7 0.9 1.7 1 0 0 1 1 1 0 SH3 domain G-alpha PF00503.20 GAP87260.1 - 6e-116 387.5 0.1 7e-116 387.2 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAP87260.1 - 1.4e-15 57.2 0.2 1.8e-10 40.6 0.1 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAP87260.1 - 0.00025 20.5 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 GAP87260.1 - 0.0022 18.2 0.1 0.96 9.7 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 GAP87260.1 - 0.085 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.20 GAP87261.1 - 0 1053.0 0.0 0 1052.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.25 GAP87263.1 - 4.4e-68 229.5 0.0 5.5e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87263.1 - 3e-32 111.9 0.0 4.2e-32 111.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAP87263.1 - 8.8e-06 24.9 0.1 1.2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAP87263.1 - 3e-05 23.5 0.1 9.7e-05 21.8 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP87263.1 - 0.0004 20.4 0.1 0.0018 18.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAP87263.1 - 0.00064 19.1 0.0 0.052 12.9 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 GAP87263.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 GAP87263.1 - 0.024 14.3 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Get5_C PF18514.1 GAP87263.1 - 0.12 12.1 0.2 0.27 11.0 0.2 1.6 1 0 0 1 1 1 0 Get5 C-terminal domain Aminotran_3 PF00202.21 GAP87264.1 - 1.2e-17 63.7 0.0 1.5e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.18 GAP87265.1 - 4e-62 209.7 0.1 6.2e-62 209.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PfkB PF00294.24 GAP87267.1 - 2e-12 47.0 0.2 6.3e-07 29.0 0.9 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase CAP_N PF01213.19 GAP87268.1 - 2.1e-115 385.6 0.0 3.3e-115 384.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 GAP87268.1 - 4.2e-58 195.4 4.5 5.7e-58 195.0 4.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 GAP87268.1 - 0.17 11.7 1.6 1.1 9.0 0.7 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor C Carn_acyltransf PF00755.20 GAP87269.1 - 9.8e-205 681.6 0.0 1.1e-204 681.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase WSC PF01822.19 GAP87270.1 - 1.8e-12 47.3 4.8 7.8e-12 45.2 4.8 2.1 1 0 0 1 1 1 1 WSC domain Glyco_hydro_16 PF00722.21 GAP87270.1 - 5.7e-05 22.7 0.4 0.0001 21.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Anoctamin PF04547.12 GAP87271.1 - 2.6e-112 376.0 8.2 3.2e-112 375.7 8.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Metallophos PF00149.28 GAP87272.1 - 1.1e-10 42.4 1.1 1.8e-10 41.7 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAP87272.1 - 1.7e-06 28.3 0.4 1.1e-05 25.6 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4360 PF14273.6 GAP87273.1 - 2.4e-30 105.7 1.6 3e-30 105.4 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pex2_Pex12 PF04757.14 GAP87274.1 - 8.3e-53 179.3 2.2 1.1e-52 178.9 2.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 GAP87274.1 - 0.00044 20.1 2.0 0.00069 19.4 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP87274.1 - 0.0014 18.4 3.9 0.0026 17.5 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP87274.1 - 0.012 15.9 4.3 0.022 15.1 4.3 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 GAP87274.1 - 0.021 15.0 2.6 0.036 14.2 2.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GAP87274.1 - 0.042 13.7 3.4 0.072 13.0 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP87274.1 - 0.05 13.6 2.6 0.095 12.7 2.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger ArfGap PF01412.18 GAP87275.1 - 1.2e-34 118.9 0.3 2.5e-34 117.8 0.3 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Tho1_MOS11_C PF18592.1 GAP87275.1 - 0.93 9.3 4.1 3.8 7.4 0.2 3.1 3 0 0 3 3 3 0 Tho1/MOS11 C-terminal domain TIM21 PF08294.11 GAP87276.1 - 2.5e-45 153.9 0.0 3.1e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 GAP87276.1 - 2e-07 30.8 0.0 3.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 NDT80_PhoG PF05224.12 GAP87277.1 - 1.2e-49 169.1 0.0 1.6e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pterin_bind PF00809.22 GAP87278.1 - 2.8e-75 253.2 0.0 7.1e-70 235.5 0.0 2.2 2 0 0 2 2 2 2 Pterin binding enzyme HPPK PF01288.20 GAP87278.1 - 4.1e-37 127.1 0.0 8.5e-37 126.1 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 GAP87279.1 - 3.7e-52 177.8 0.4 5.2e-52 177.3 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAP87279.1 - 2.4e-10 40.0 2.3 1.1e-09 37.8 2.3 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAP87279.1 - 1.3e-05 24.5 1.6 2e-05 23.8 1.6 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 GAP87279.1 - 0.0038 16.4 1.6 0.008 15.3 1.6 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 GAP87279.1 - 0.025 13.8 0.2 0.04 13.1 0.2 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Radial_spoke_3 PF06098.11 GAP87279.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 adh_short_C2 PF13561.6 GAP87280.1 - 4.8e-38 131.0 0.2 1.7e-37 129.2 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP87280.1 - 3.4e-37 127.8 0.0 6.3e-37 126.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP87280.1 - 8.2e-10 38.9 2.3 1e-08 35.3 2.3 2.1 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 GAP87280.1 - 0.00087 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 GAP87280.1 - 0.089 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MIP PF00230.20 GAP87281.1 - 0.013 15.2 0.7 0.018 14.7 0.7 1.2 1 0 0 1 1 1 0 Major intrinsic protein SUR7 PF06687.12 GAP87282.1 - 1.2e-20 74.0 0.1 1.4e-20 73.8 0.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 GAP87282.1 - 0.014 15.4 3.9 0.014 15.4 3.9 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 FtsX PF02687.21 GAP87282.1 - 0.059 13.8 13.2 0.043 14.3 2.6 3.1 2 1 1 3 3 3 0 FtsX-like permease family DUF1218 PF06749.12 GAP87282.1 - 1.3 9.6 5.2 22 5.6 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) MscL PF01741.18 GAP87283.1 - 8.3e-18 64.8 0.2 1e-17 64.5 0.2 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.22 GAP87283.1 - 0.091 12.7 2.3 0.15 12.0 2.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PRA1 PF03208.19 GAP87283.1 - 0.11 12.1 0.2 0.11 12.1 0.2 1.6 2 0 0 2 2 2 0 PRA1 family protein DZR PF12773.7 GAP87283.1 - 0.12 12.5 1.2 0.17 11.9 1.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-BED PF02892.15 GAP87283.1 - 0.37 10.8 5.0 0.95 9.5 5.0 1.7 1 1 0 1 1 1 0 BED zinc finger Dioxygenase_C PF00775.21 GAP87284.1 - 1.8e-08 34.1 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase WD40 PF00400.32 GAP87286.1 - 2.2e-14 53.6 16.6 6e-07 30.1 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP87286.1 - 0.0098 16.2 0.2 0.66 10.3 0.0 3.2 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Tim17 PF02466.19 GAP87287.1 - 6.3e-30 103.8 8.3 7.9e-30 103.5 8.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family p450 PF00067.22 GAP87288.1 - 1.3e-14 53.9 0.0 1.7e-13 50.2 0.0 2.2 2 1 0 2 2 2 1 Cytochrome P450 3Beta_HSD PF01073.19 GAP87289.1 - 6.6e-27 94.2 0.0 3.5e-26 91.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAP87289.1 - 9.2e-13 48.2 0.1 1.7e-12 47.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAP87289.1 - 3.8e-10 39.4 0.0 1e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 GAP87289.1 - 2.6e-07 30.7 0.0 6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 GAP87289.1 - 1.1e-06 28.7 0.0 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 GAP87289.1 - 2.9e-06 26.7 0.0 5.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 GAP87289.1 - 0.00022 20.8 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 GAP87289.1 - 0.0047 16.4 0.1 0.008 15.6 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Pro_CA PF00484.19 GAP87290.1 - 3e-14 53.6 0.3 6.3e-13 49.3 0.3 2.0 1 1 0 1 1 1 1 Carbonic anhydrase DUF3605 PF12239.8 GAP87291.1 - 2.7e-57 193.4 2.2 3.3e-57 193.1 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) P2_Phage_GpR PF06891.11 GAP87291.1 - 0.05 13.7 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) UDPGP PF01704.18 GAP87292.1 - 1.9e-190 632.8 0.1 2.3e-190 632.6 0.1 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 GAP87292.1 - 0.072 11.9 0.4 1.9 7.2 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4301) ING PF12998.7 GAP87293.1 - 3.3e-22 79.0 2.0 4.9e-22 78.4 2.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 GAP87293.1 - 3.7e-05 23.5 7.5 6.8e-05 22.7 7.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 GAP87293.1 - 0.058 13.6 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Hist_deacetyl PF00850.19 GAP87294.1 - 1.5e-77 261.1 0.0 2e-77 260.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RNA_replicase_B PF03431.13 GAP87294.1 - 0.04 12.4 0.0 0.35 9.3 0.0 1.9 2 0 0 2 2 2 0 RNA replicase, beta-chain DUF3526 PF12040.8 GAP87294.1 - 0.12 12.9 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) Peptidase_M28 PF04389.17 GAP87295.1 - 2.1e-37 128.8 0.0 3.5e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAP87295.1 - 9.6e-12 44.8 0.1 4.2e-11 42.7 0.2 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 GAP87295.1 - 0.0018 18.0 0.0 0.0043 16.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.16 GAP87296.1 - 3.1e-08 32.9 28.8 8.7e-05 21.6 11.9 2.8 2 2 0 2 2 2 2 Major Facilitator Superfamily SUN PF03856.13 GAP87297.1 - 1.9e-80 269.8 6.1 2.5e-80 269.5 6.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) zf-H2C2_2 PF13465.6 GAP87298.1 - 8.1e-10 38.7 21.2 5.7e-07 29.7 2.5 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAP87298.1 - 2.2e-09 37.2 24.5 0.0044 17.4 7.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP87298.1 - 1.2e-06 28.8 21.3 0.04 14.8 6.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger Rad50_zn_hook PF04423.14 GAP87298.1 - 0.0019 18.0 2.9 0.067 13.0 0.7 2.6 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 GAP87298.1 - 0.0066 16.4 19.4 0.1 12.7 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_9 PF16293.5 GAP87298.1 - 0.012 15.4 5.2 1.8 8.5 0.3 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 GAP87298.1 - 0.072 13.2 6.6 0.11 12.6 1.9 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.12 GAP87298.1 - 0.081 13.2 13.3 0.2 12.0 8.7 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 GAP87298.1 - 0.53 10.6 17.2 7.2 7.0 8.5 3.8 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding DZR PF12773.7 GAP87298.1 - 0.71 9.9 7.9 3 7.9 6.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-CHCC PF10276.9 GAP87298.1 - 0.8 9.8 6.2 2.4 8.3 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger domain zinc-ribbons_6 PF07191.12 GAP87298.1 - 2.1 8.4 5.8 11 6.1 5.8 2.0 1 1 0 1 1 1 0 zinc-ribbons zinc_ribbon_9 PF14369.6 GAP87298.1 - 2.4 8.5 6.0 21 5.5 0.1 2.9 2 1 0 2 2 2 0 zinc-ribbon zf-C2HC_2 PF13913.6 GAP87298.1 - 3 7.9 8.2 0.16 11.9 0.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GAGA PF09237.11 GAP87298.1 - 6.3 6.7 8.1 3.3 7.6 1.2 3.1 1 1 2 3 3 3 0 GAGA factor zf-C2H2_2 PF12756.7 GAP87298.1 - 7.6 6.9 15.9 24 5.3 12.1 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SIL1 PF16782.5 GAP87300.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 V-ATPase_H_N PF03224.14 GAP87300.1 - 0.15 11.3 0.1 0.26 10.5 0.1 1.3 1 1 0 1 1 1 0 V-ATPase subunit H RecR PF02132.15 GAP87302.1 - 0.019 14.6 0.2 0.033 13.8 0.2 1.6 1 1 0 1 1 1 0 RecR protein DZR PF12773.7 GAP87302.1 - 0.049 13.7 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Double zinc ribbon 3-HAO PF06052.12 GAP87302.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase 3-HAO PF06052.12 GAP87303.1 - 1.7e-54 183.6 0.0 8.3e-54 181.3 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 GAP87303.1 - 0.00022 20.9 0.1 0.19 11.5 0.0 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 GAP87303.1 - 0.00028 20.5 0.1 0.00035 20.2 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_4 PF08007.12 GAP87303.1 - 0.002 17.6 0.0 0.0024 17.4 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Carb_kinase PF01256.17 GAP87304.1 - 1.7e-53 181.6 0.0 2.6e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 GAP87304.1 - 0.00073 19.0 0.0 0.0043 16.5 0.0 1.9 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family ATP-synt_ab PF00006.25 GAP87305.1 - 1.1e-72 244.2 0.0 1.6e-72 243.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 GAP87305.1 - 1.4e-47 161.1 0.1 2.5e-47 160.3 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 GAP87305.1 - 6e-15 55.5 2.9 1.3e-14 54.4 2.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.18 GAP87305.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea HET PF06985.11 GAP87306.1 - 0.0002 21.7 0.1 0.021 15.2 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AOX PF01786.17 GAP87307.1 - 2.4e-90 301.9 0.1 2.7e-90 301.7 0.1 1.0 1 0 0 1 1 1 1 Alternative oxidase Aminotran_4 PF01063.19 GAP87308.1 - 1.7e-22 80.4 0.0 2.2e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Glyco_transf_20 PF00982.21 GAP87309.1 - 2.4e-160 534.3 0.0 3.2e-160 533.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 GAP87309.1 - 1.8e-42 145.0 0.0 2.9e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase WD40 PF00400.32 GAP87310.1 - 3.4e-48 160.6 25.6 5.1e-07 30.3 0.0 9.2 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP87310.1 - 2.3e-19 69.4 0.1 0.00061 20.0 0.0 6.2 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAP87310.1 - 9.4e-08 32.2 0.0 0.0015 18.5 0.0 3.2 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAP87310.1 - 1.3e-05 24.4 0.2 0.23 10.4 0.0 5.1 3 3 3 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 GAP87310.1 - 0.00033 21.1 0.1 0.00071 20.1 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 GAP87310.1 - 0.001 17.8 0.2 0.91 8.1 0.1 3.3 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 GAP87310.1 - 0.012 15.3 0.8 2.3 8.0 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF3560 PF12083.8 GAP87310.1 - 0.029 14.5 0.6 0.068 13.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) Nucleoporin_N PF08801.11 GAP87310.1 - 0.059 12.1 5.4 0.33 9.7 2.3 3.6 1 1 2 3 3 3 0 Nup133 N terminal like Mcl1_mid PF12341.8 GAP87310.1 - 0.084 12.2 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Cytotoxic PF09000.10 GAP87310.1 - 0.16 12.3 2.1 65 4.0 0.0 3.9 4 0 0 4 4 4 0 Cytotoxic PD40 PF07676.12 GAP87310.1 - 0.2 11.6 4.2 7 6.7 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat MutS_V PF00488.21 GAP87311.1 - 8.3e-63 211.8 0.2 1.4e-62 211.1 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAP87311.1 - 2.3e-28 99.7 2.7 5.4e-28 98.5 2.7 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 GAP87311.1 - 0.0002 21.7 0.1 0.00088 19.6 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 GAP87311.1 - 0.00029 21.1 0.3 0.00078 19.7 0.3 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.6 GAP87311.1 - 0.059 13.4 0.0 0.22 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain B1 PF02246.15 GAP87311.1 - 0.11 12.5 0.4 0.42 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein L b1 domain FAD_binding_3 PF01494.19 GAP87312.1 - 5.3e-75 252.9 0.0 1e-74 251.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP87312.1 - 5.5e-06 25.8 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP87312.1 - 9.6e-06 24.9 0.0 4.5e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 GAP87312.1 - 6.2e-05 22.7 0.3 0.008 15.8 0.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAP87312.1 - 0.00018 20.3 0.1 0.00059 18.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAP87312.1 - 0.00075 18.8 0.0 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP87312.1 - 0.00095 19.4 0.0 0.0054 16.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAP87312.1 - 0.00097 18.3 0.4 0.0072 15.4 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein TrkA_N PF02254.18 GAP87312.1 - 0.0013 18.9 0.0 0.0033 17.7 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain SE PF08491.10 GAP87312.1 - 0.0018 17.4 0.0 0.004 16.3 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase FAD_oxidored PF12831.7 GAP87312.1 - 0.0024 17.3 0.0 0.085 12.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAP87312.1 - 0.0035 17.9 0.0 0.15 12.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP87312.1 - 0.0098 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 GAP87312.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 GAP87312.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 GAP87312.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_hydro_43 PF04616.14 GAP87313.1 - 1.1e-55 189.1 8.0 1.4e-55 188.7 8.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1080 PF06439.11 GAP87313.1 - 0.00079 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Glyco_hydro_32N PF00251.20 GAP87313.1 - 0.0021 17.7 1.5 0.0034 17.0 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Laminin_G_2 PF02210.24 GAP87313.1 - 0.024 15.2 0.0 0.39 11.3 0.0 2.3 2 0 0 2 2 2 0 Laminin G domain O-FucT PF10250.9 GAP87314.1 - 1.6e-11 44.5 0.0 1.9e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RSN1_7TM PF02714.15 GAP87315.1 - 8.6e-78 261.4 23.6 1.7e-77 260.4 23.6 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 GAP87315.1 - 4.6e-39 134.5 0.0 7e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 GAP87315.1 - 2.1e-37 128.3 1.2 2.1e-37 128.3 1.2 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 GAP87315.1 - 0.0035 16.2 0.7 0.0035 16.2 0.7 2.2 2 0 0 2 2 2 1 Calcium-activated chloride channel MutS_V PF00488.21 GAP87316.1 - 1.6e-67 227.2 0.2 1.6e-66 224.0 0.0 2.6 3 1 0 3 3 3 1 MutS domain V MutS_III PF05192.18 GAP87316.1 - 4e-36 125.0 0.9 4e-36 125.0 0.9 1.9 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 GAP87316.1 - 6.1e-29 100.6 0.0 1.5e-28 99.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 GAP87316.1 - 4e-09 36.9 0.1 3e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 GAP87316.1 - 0.00024 21.4 0.0 0.0037 17.6 0.0 2.7 2 0 0 2 2 2 1 MutS family domain IV DUF4911 PF16256.5 GAP87316.1 - 0.023 14.6 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) AAA_27 PF13514.6 GAP87316.1 - 0.057 13.0 0.0 0.23 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain PBP1_TM PF14812.6 GAP87316.1 - 4.2 7.8 9.5 2.9 8.3 6.6 2.2 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2_2 PF12756.7 GAP87317.1 - 0.28 11.5 1.3 0.61 10.5 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ThiF PF00899.21 GAP87318.1 - 2e-65 220.6 0.0 2.8e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 GAP87318.1 - 1.9e-26 92.0 0.0 3.1e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 GAP87318.1 - 0.00047 20.2 1.4 0.0013 18.8 0.1 2.3 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase DUF3419 PF11899.8 GAP87318.1 - 0.17 11.0 0.1 0.27 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) UBA_e1_thiolCys PF10585.9 GAP87318.1 - 0.2 11.5 1.8 9.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Ecm33 PF12454.8 GAP87318.1 - 0.28 11.4 4.2 0.32 11.2 2.9 1.8 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Telomere_reg-2 PF10193.9 GAP87319.1 - 2.8e-36 124.3 0.0 1.7e-35 121.8 0.0 2.3 2 0 0 2 2 2 1 Telomere length regulation protein Pkinase PF00069.25 GAP87320.1 - 4.5e-55 186.9 0.0 6.2e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87320.1 - 2.6e-40 138.4 0.0 3.7e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP87320.1 - 4.6e-05 22.9 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 GAP87320.1 - 0.0012 17.7 0.0 0.0026 16.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAP87320.1 - 0.037 14.0 0.0 1.3 8.9 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAP87320.1 - 0.043 12.8 0.0 0.8 8.6 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 GAP87320.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.29 GAP87321.1 - 1.7e-55 187.0 0.0 3.2e-43 147.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 GAP87321.1 - 1.6e-28 98.9 0.2 4.2e-28 97.6 0.2 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 GAP87321.1 - 7.6e-14 51.3 0.0 5.5e-08 32.5 0.0 2.7 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 GAP87321.1 - 7.5e-12 45.9 2.4 5.4e-05 23.6 0.1 4.6 2 2 2 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 GAP87321.1 - 1.1e-08 35.3 0.0 0.00025 21.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 GAP87321.1 - 9.5e-08 32.1 0.6 8.6e-05 22.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_7 PF12775.7 GAP87321.1 - 8.2e-07 28.7 0.0 4.4e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 GAP87321.1 - 1.6e-06 28.2 0.0 0.0046 17.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 GAP87321.1 - 4.3e-06 26.7 0.1 0.012 15.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 GAP87321.1 - 4.9e-06 26.6 0.1 0.026 14.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP87321.1 - 5.5e-06 26.7 1.4 0.07 13.4 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 GAP87321.1 - 6.7e-06 26.7 0.1 0.019 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAP87321.1 - 7.2e-06 26.2 0.0 0.19 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 GAP87321.1 - 2.3e-05 24.2 0.0 0.015 15.1 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 GAP87321.1 - 0.00017 21.5 0.0 0.17 11.6 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 GAP87321.1 - 0.0002 21.0 0.8 1.4 8.4 0.0 3.2 2 1 0 3 3 3 2 AAA domain TIP49 PF06068.13 GAP87321.1 - 0.00035 19.9 0.0 0.68 9.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 GAP87321.1 - 0.00088 19.0 0.2 0.74 9.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 GAP87321.1 - 0.00093 19.6 0.0 1.6 9.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 GAP87321.1 - 0.0012 18.3 0.1 0.8 9.0 0.1 2.6 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 GAP87321.1 - 0.0014 18.7 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 GAP87321.1 - 0.002 18.4 0.1 0.49 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 GAP87321.1 - 0.0022 17.3 0.1 0.7 9.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 GAP87321.1 - 0.0066 16.2 0.0 0.42 10.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 GAP87321.1 - 0.0076 16.7 0.1 2.5 8.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 GAP87321.1 - 0.019 14.4 0.0 5.1 6.4 0.0 2.6 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 GAP87321.1 - 0.038 14.5 0.0 15 6.1 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Cytidylate_kin2 PF13189.6 GAP87321.1 - 0.038 14.1 0.0 5 7.2 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family NTPase_1 PF03266.15 GAP87321.1 - 0.039 13.9 0.1 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 NTPase KTI12 PF08433.10 GAP87321.1 - 0.042 13.3 0.1 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PduV-EutP PF10662.9 GAP87321.1 - 0.049 13.4 0.1 0.97 9.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.9 GAP87321.1 - 0.053 12.8 0.0 9.2 5.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 GAP87321.1 - 0.062 13.2 0.0 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_3 PF07726.11 GAP87321.1 - 0.067 13.1 0.0 8.4 6.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 GAP87321.1 - 0.068 13.3 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase APS_kinase PF01583.20 GAP87321.1 - 0.068 13.1 0.3 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.13 GAP87321.1 - 0.081 12.1 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 GAP87321.1 - 0.087 12.0 0.3 13 4.8 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 GAP87321.1 - 0.09 12.5 0.2 18 4.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAP87321.1 - 0.11 12.4 0.0 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PEX-2N PF09263.10 GAP87321.1 - 0.11 12.8 0.6 5.1 7.5 0.0 2.9 2 1 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal AAA_29 PF13555.6 GAP87321.1 - 0.15 11.9 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 GAP87321.1 - 0.57 9.7 1.8 2.3 7.8 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 GAP87322.1 - 2.5e-104 347.3 0.0 4e-104 346.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAP87322.1 - 1e-31 109.4 0.8 1.8e-31 108.6 0.8 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAP87322.1 - 4.6e-20 71.8 2.1 1.1e-19 70.7 2.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAP87322.1 - 8.6e-20 71.3 2.0 2.4e-19 69.8 2.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAP87322.1 - 1.2e-07 31.3 0.0 1e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAP87322.1 - 5.4e-06 26.4 0.0 1.9e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 GAP87322.1 - 0.00059 19.6 0.1 0.002 17.9 0.1 2.0 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase_C PF13335.6 GAP87322.1 - 0.0052 17.4 2.0 0.021 15.5 1.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 GAP87322.1 - 0.013 15.4 0.0 0.048 13.5 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAP87322.1 - 0.15 11.8 0.0 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-HYPF PF07503.12 GAP87322.1 - 0.16 11.7 1.4 0.36 10.6 1.4 1.6 1 0 0 1 1 1 0 HypF finger N36 PF11438.8 GAP87322.1 - 2.4 8.0 4.9 1.8 8.5 0.6 2.5 2 0 0 2 2 2 0 36-mer N-terminal peptide of the N protein (N36) DAP3 PF10236.9 GAP87323.1 - 1.2e-84 284.1 0.0 1.5e-84 283.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 T2SSE PF00437.20 GAP87323.1 - 0.047 12.7 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 GAP87323.1 - 0.08 13.3 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain RRS1 PF04939.12 GAP87324.1 - 6.5e-42 143.1 2.2 8e-42 142.9 2.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.27 GAP87325.1 - 3.7e-29 101.5 0.0 6.1e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.21 GAP87326.1 - 2.7e-56 186.9 8.3 1.9e-12 46.7 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 GAP87326.1 - 0.00049 19.3 0.0 0.54 9.3 0.0 3.4 2 1 2 4 4 4 3 Squalene-hopene cyclase N-terminal domain EF-hand_7 PF13499.6 GAP87326.1 - 0.094 13.2 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair RNA_pol_A_bac PF01000.26 GAP87327.1 - 2.4e-23 82.6 0.0 5.6e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 GAP87327.1 - 1e-21 76.1 0.0 1.4e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain FAD_binding_3 PF01494.19 GAP87328.1 - 1.6e-21 76.9 0.0 2.3e-19 69.9 0.0 2.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 GAP87328.1 - 2.4e-06 26.9 0.0 0.0019 17.3 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAP87328.1 - 9.6e-05 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 GAP87328.1 - 0.00015 20.8 0.0 0.057 12.3 0.0 2.8 2 1 1 3 3 3 2 Tryptophan halogenase DAO PF01266.24 GAP87328.1 - 0.00025 20.7 0.1 0.011 15.4 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 GAP87328.1 - 0.0021 17.1 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 GAP87328.1 - 0.0026 17.0 0.0 0.02 14.2 0.0 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP87328.1 - 0.0056 15.9 0.0 0.059 12.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 GAP87328.1 - 0.0063 15.3 0.0 0.008 14.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein K_oxygenase PF13434.6 GAP87328.1 - 0.0095 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAP87328.1 - 0.019 15.2 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CENP-L PF13092.6 GAP87328.1 - 0.12 12.6 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 Pil1 PF13805.6 GAP87329.1 - 2.3e-105 351.8 5.7 3.1e-105 351.4 5.7 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 BAR_3 PF16746.5 GAP87329.1 - 0.037 13.7 0.2 0.061 13.0 0.2 1.5 1 1 0 1 1 1 0 BAR domain of APPL family Ribophorin_I PF04597.14 GAP87330.1 - 2.8e-148 494.8 1.8 3.2e-148 494.6 1.8 1.0 1 0 0 1 1 1 1 Ribophorin I HNH_2 PF13391.6 GAP87331.1 - 6.9e-12 45.3 0.8 1.9e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease Peptidase_C97 PF05903.14 GAP87332.1 - 1.3e-05 25.1 0.2 2.7e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 GAP87332.1 - 0.00056 20.3 0.1 0.00097 19.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF778) DUF4105 PF13387.6 GAP87332.1 - 0.006 16.2 0.1 0.0088 15.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) LRAT PF04970.13 GAP87332.1 - 0.026 14.8 2.8 0.54 10.6 0.4 2.7 2 1 1 3 3 3 0 Lecithin retinol acyltransferase Hexokinase_2 PF03727.16 GAP87333.1 - 5.3e-82 274.8 0.0 7.4e-82 274.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 GAP87333.1 - 3.5e-72 242.5 0.0 6.3e-72 241.7 0.0 1.4 2 0 0 2 2 2 1 Hexokinase Ank_2 PF12796.7 GAP87334.1 - 0.037 14.6 0.1 3.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Roughex PF06020.11 GAP87334.1 - 7.8 5.5 9.1 47 2.9 9.1 1.9 1 1 0 1 1 1 0 Drosophila roughex protein VTC PF09359.10 GAP87335.1 - 2.8e-98 328.7 0.0 2.8e-98 328.7 0.0 1.5 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 GAP87335.1 - 1.4e-13 51.1 3.2 2.6e-13 50.2 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 GAP87335.1 - 2.5e-11 44.1 18.9 4e-06 27.0 0.6 4.1 2 1 1 4 4 4 3 SPX domain Cys_Met_Meta_PP PF01053.20 GAP87336.1 - 3.1e-21 75.3 0.0 4.3e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TPR_11 PF13414.6 GAP87336.1 - 0.004 16.8 0.3 0.06 13.0 0.0 2.9 3 0 0 3 3 3 1 TPR repeat Complex1_49kDa PF00346.19 GAP87338.1 - 7.6e-123 408.9 0.0 1.1e-122 408.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 GAP87338.1 - 0.017 14.0 0.0 0.03 13.2 0.0 1.3 1 1 0 1 1 1 0 Nickel-dependent hydrogenase Glyco_hydro_2_C PF02836.17 GAP87339.1 - 1e-12 47.8 0.0 1.4e-11 44.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 GAP87339.1 - 3.5e-10 40.5 0.0 9.4e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 GAP87339.1 - 1.8e-06 28.0 0.0 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain MCM PF00493.23 GAP87340.1 - 7.2e-100 332.7 0.0 1e-99 332.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 GAP87340.1 - 8.8e-40 135.5 1.4 1.6e-39 134.6 1.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAP87340.1 - 3.2e-27 94.8 3.7 3.2e-27 94.8 3.7 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 GAP87340.1 - 1.7e-17 63.9 0.2 5.6e-17 62.2 0.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 GAP87340.1 - 1.1e-05 25.5 0.0 6.2e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 GAP87340.1 - 2e-05 24.1 0.0 0.0006 19.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAP87340.1 - 0.0012 18.7 0.0 0.0052 16.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAP87340.1 - 0.13 12.0 0.2 3.6 7.2 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Clat_adaptor_s PF01217.20 GAP87341.1 - 1.3e-14 54.3 0.7 1.8e-14 53.9 0.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.18 GAP87342.1 - 4.4e-57 192.5 0.0 6.3e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 GAP87342.1 - 1.2e-31 110.1 0.0 2.1e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding COG4 PF08318.12 GAP87343.1 - 5.8e-125 416.8 0.0 8e-125 416.4 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein THOC7 PF05615.13 GAP87344.1 - 9.4e-41 139.2 6.0 9.4e-40 135.9 0.1 2.2 1 1 1 2 2 2 2 Tho complex subunit 7 FUSC PF04632.12 GAP87344.1 - 0.3 9.6 13.7 0.39 9.2 13.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sigma70_ner PF04546.13 GAP87344.1 - 0.74 9.7 9.7 3.4 7.5 0.1 2.4 2 1 0 2 2 2 0 Sigma-70, non-essential region CysG_dimeriser PF10414.9 GAP87344.1 - 2.2 8.1 16.6 2.6 7.9 2.0 2.7 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region TBCA PF02970.16 GAP87345.1 - 7.1e-24 84.0 4.0 8.9e-24 83.6 4.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Csm1_N PF18504.1 GAP87345.1 - 0.0031 17.8 3.2 0.16 12.3 0.3 2.3 1 1 1 2 2 2 2 Csm1 N-terminal domain APC_N_CC PF16689.5 GAP87345.1 - 0.007 16.4 0.2 0.022 14.8 0.1 1.9 2 0 0 2 2 2 1 Coiled-coil N-terminus of APC, dimerisation domain Spectrin PF00435.21 GAP87345.1 - 0.019 15.5 1.9 0.023 15.1 1.1 1.5 1 1 0 1 1 1 0 Spectrin repeat DUF2408 PF10303.9 GAP87345.1 - 0.025 15.1 0.5 0.03 14.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) COG2 PF06148.11 GAP87345.1 - 0.059 13.5 1.7 0.15 12.1 0.4 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HMMR_N PF15905.5 GAP87345.1 - 0.17 11.3 5.6 2.3 7.6 0.3 1.9 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF1993 PF09351.10 GAP87345.1 - 0.23 11.6 1.3 0.3 11.2 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) COX17 PF05051.13 GAP87346.1 - 2.9e-21 75.5 5.7 3.6e-21 75.3 5.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Sugar_tr PF00083.24 GAP87347.1 - 8.8e-85 285.2 17.8 1e-84 285.1 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP87347.1 - 3.5e-34 118.3 51.9 4.4e-32 111.4 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAP87347.1 - 1.5e-07 30.3 13.6 1.7e-07 30.1 0.4 2.2 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Complex1_LYR PF05347.15 GAP87348.1 - 3e-16 59.2 1.4 9.1e-16 57.7 1.4 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAP87348.1 - 3.1e-05 24.6 0.2 0.00011 22.9 0.2 2.0 1 0 0 1 1 1 1 Complex1_LYR-like Zn_clus PF00172.18 GAP87349.1 - 1e-06 28.8 9.8 3.2e-06 27.2 9.8 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_7 PF02591.15 GAP87349.1 - 0.047 13.9 0.2 0.047 13.9 0.2 2.9 3 0 0 3 3 3 0 C4-type zinc ribbon domain SURF4 PF02077.15 GAP87350.1 - 2.4e-95 319.2 8.0 2.7e-95 319.0 8.0 1.0 1 0 0 1 1 1 1 SURF4 family FAD_binding_4 PF01565.23 GAP87352.1 - 9.7e-22 77.2 0.2 1.7e-21 76.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Tti2 PF10521.9 GAP87353.1 - 4.7e-73 246.2 0.0 1.6e-68 231.3 0.0 2.2 1 1 1 2 2 2 2 Tti2 family Syja_N PF02383.18 GAP87354.1 - 8.6e-77 258.6 0.0 2.2e-76 257.2 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain DUF1077 PF06417.12 GAP87355.1 - 1.2e-50 170.5 3.7 1.5e-50 170.1 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 GAP87356.1 - 5.9e-106 355.1 11.2 3.6e-61 207.3 8.1 2.0 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 GAP87356.1 - 4.8e-55 186.0 9.2 6.2e-54 182.4 0.1 3.9 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAP87356.1 - 5.4e-17 62.0 6.0 1e-09 38.6 0.2 4.7 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 GAP87356.1 - 6.2e-12 44.7 5.6 8.7e-05 22.5 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 GAP87356.1 - 6.4e-08 32.9 4.7 0.18 12.4 0.0 6.4 5 1 1 6 6 6 2 HEAT-like repeat Arm PF00514.23 GAP87356.1 - 9.1e-05 22.4 1.3 1.5 8.9 0.0 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 GAP87356.1 - 0.0014 18.2 3.2 0.88 9.1 0.4 3.5 3 1 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 GAP87356.1 - 0.0095 16.1 1.0 2.9 8.1 0.0 3.5 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 NBD94 PF16830.5 GAP87356.1 - 0.013 15.9 2.0 0.013 15.9 2.0 2.1 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH DUF4042 PF13251.6 GAP87356.1 - 0.069 12.8 0.4 3.7 7.2 0.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4042) Rad60-SLD_2 PF13881.6 GAP87358.1 - 5.2e-13 49.1 0.1 1.3e-12 47.8 0.1 1.6 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAP87358.1 - 0.00016 22.2 0.0 0.00035 21.1 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 GAP87358.1 - 0.0003 20.5 0.0 0.00063 19.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family UMP1 PF05348.11 GAP87359.1 - 9e-30 103.3 0.0 1.7e-29 102.4 0.0 1.5 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.27 GAP87360.1 - 9.7e-24 84.4 0.0 2e-10 41.3 0.0 3.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAP87360.1 - 9.3e-06 25.7 7.9 0.029 14.2 0.6 3.5 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 GAP87360.1 - 0.0001 22.5 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 GAP87360.1 - 0.00019 22.0 0.6 0.0075 16.8 0.8 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAP87360.1 - 0.00085 19.0 0.0 0.093 12.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 GAP87360.1 - 0.016 15.4 0.0 8.1 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAP87360.1 - 0.018 15.3 0.0 8.1 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 GAP87360.1 - 0.04 13.7 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 GAP87360.1 - 0.064 13.7 0.2 0.67 10.4 0.0 2.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAP87360.1 - 0.074 13.5 0.0 4 7.9 0.0 2.6 3 0 0 3 3 3 0 RNA helicase AAA_16 PF13191.6 GAP87360.1 - 0.14 12.5 0.0 11 6.4 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Ploopntkinase1 PF18748.1 GAP87360.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 ATP_bind_1 PF03029.17 GAP87360.1 - 0.16 11.8 0.0 6.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 GAP87360.1 - 0.18 12.4 0.0 18 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain CorA PF01544.18 GAP87362.1 - 0.0032 16.8 0.9 0.0032 16.8 0.9 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Pkinase PF00069.25 GAP87363.1 - 3e-18 66.1 0.0 2.2e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87363.1 - 1e-08 34.8 0.0 3.6e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP87363.1 - 0.14 12.1 0.0 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 GAP87364.1 - 2.4e-17 63.2 0.0 1.8e-11 44.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87364.1 - 6e-13 48.7 0.0 1.7e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP87364.1 - 0.089 12.7 0.0 15 5.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family PBP_sp32 PF07222.12 GAP87365.1 - 0.00046 19.7 8.0 0.00049 19.6 8.0 1.0 1 0 0 1 1 1 1 Proacrosin binding protein sp32 eIF-3_zeta PF05091.12 GAP87365.1 - 0.01 14.9 3.1 0.012 14.7 3.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.17 GAP87365.1 - 0.039 14.1 2.4 0.045 13.9 2.4 1.0 1 0 0 1 1 1 0 DDHD domain AAA_23 PF13476.6 GAP87365.1 - 0.043 14.3 9.7 0.049 14.1 9.7 1.1 1 0 0 1 1 1 0 AAA domain RMI1_N PF08585.12 GAP87365.1 - 0.049 13.4 4.1 0.053 13.3 4.1 1.1 1 0 0 1 1 1 0 RecQ mediated genome instability protein AAA_11 PF13086.6 GAP87365.1 - 0.061 13.1 5.4 0.065 13.0 5.4 1.1 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 GAP87365.1 - 0.067 13.0 10.3 0.077 12.8 10.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 GAP87365.1 - 0.073 12.9 9.3 0.077 12.8 9.3 1.1 1 0 0 1 1 1 0 Coilin N-terminus EIIBC-GUT_N PF03612.14 GAP87365.1 - 0.16 11.7 1.9 0.15 11.8 1.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_S49_N PF08496.10 GAP87365.1 - 0.18 11.8 8.6 0.21 11.6 8.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Trypan_PARP PF05887.11 GAP87365.1 - 0.3 11.1 5.0 0.38 10.7 5.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Presenilin PF01080.17 GAP87365.1 - 0.3 9.8 4.0 0.31 9.7 4.0 1.1 1 0 0 1 1 1 0 Presenilin DUF1682 PF07946.14 GAP87365.1 - 0.36 10.0 23.8 0.48 9.6 23.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Connexin PF00029.19 GAP87365.1 - 0.38 10.5 7.6 0.43 10.3 7.6 1.2 1 0 0 1 1 1 0 Connexin U79_P34 PF03064.16 GAP87365.1 - 0.39 10.1 12.0 0.42 9.9 12.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ORC_WH_C PF18137.1 GAP87365.1 - 0.45 10.6 9.4 0.6 10.2 9.4 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF3987 PF13148.6 GAP87365.1 - 0.48 9.4 6.7 0.47 9.4 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CDC45 PF02724.14 GAP87365.1 - 0.55 8.5 7.4 0.58 8.4 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.19 GAP87365.1 - 0.96 7.3 4.7 0.97 7.3 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Serinc PF03348.15 GAP87365.1 - 1 8.2 1.8 1 8.2 1.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2828 PF11443.8 GAP87365.1 - 1.4 7.0 9.2 1.5 6.8 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) ALMT PF11744.8 GAP87365.1 - 1.9 7.2 5.5 2.1 7.1 5.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RPN2_C PF18004.1 GAP87365.1 - 2.7 7.9 16.8 3.6 7.5 16.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sec62 PF03839.16 GAP87365.1 - 4.1 6.9 8.1 4.7 6.7 8.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4337 PF14235.6 GAP87365.1 - 6.4 6.9 7.4 7.2 6.7 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2956 PF11169.8 GAP87365.1 - 6.5 7.0 13.6 11 6.3 13.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Pectate_lyase22 PF14583.6 GAP87366.1 - 0.15 10.7 0.1 0.16 10.6 0.1 1.0 1 0 0 1 1 1 0 Oligogalacturonate lyase DUF1771 PF08590.10 GAP87367.1 - 1.1e-14 54.6 11.1 2.2e-14 53.6 11.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 GAP87367.1 - 2.7e-08 33.6 7.6 6.4e-06 26.0 0.6 2.8 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 GAP87367.1 - 7.1e-08 32.7 0.0 3.5e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.24 GAP87367.1 - 3.4e-05 23.6 1.8 0.0091 15.9 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 GAP87367.1 - 0.00012 22.4 5.0 0.19 12.3 0.5 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 GAP87367.1 - 0.00045 20.0 10.6 0.0026 17.5 0.4 3.0 2 1 0 2 2 2 1 CCCH-type zinc finger HBS1_N PF08938.10 GAP87367.1 - 0.027 14.8 0.0 0.068 13.5 0.0 1.7 1 0 0 1 1 1 0 HBS1 N-terminus YscJ_FliF PF01514.17 GAP87367.1 - 0.034 13.8 0.2 0.053 13.2 0.2 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family zf-CCCH_3 PF15663.5 GAP87367.1 - 0.14 12.4 2.5 6.9 6.9 0.1 2.3 1 1 1 2 2 2 0 Zinc-finger containing family Torus PF16131.5 GAP87367.1 - 0.15 12.7 5.0 2.2 9.0 0.4 2.4 1 1 1 2 2 2 0 Torus domain Cupin_8 PF13621.6 GAP87368.1 - 7.4e-16 58.6 0.1 2.1e-13 50.6 0.1 2.3 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 GAP87368.1 - 1.5e-10 41.5 0.0 3.6e-10 40.3 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 GAP87368.1 - 3.3e-08 33.3 0.0 9.5e-08 31.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP87368.1 - 4.1e-05 23.3 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAP87368.1 - 0.016 15.0 0.4 0.067 13.1 0.0 2.0 2 0 0 2 2 2 0 F-box DEAD PF00270.29 GAP87369.1 - 1.9e-45 154.7 0.7 3.2e-45 154.1 0.7 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP87369.1 - 4.8e-32 110.6 0.2 8.8e-31 106.5 0.0 2.7 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP87369.1 - 8.9e-06 25.8 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 GAP87369.1 - 0.00072 19.3 0.1 0.0015 18.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAP87369.1 - 0.00093 19.6 1.0 0.0052 17.1 0.3 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAP87369.1 - 0.023 15.0 0.5 0.12 12.7 0.5 2.2 1 1 0 1 1 1 0 AAA domain IL17R_D_N PF16742.5 GAP87369.1 - 0.035 14.1 0.0 0.095 12.8 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D CMS1 PF14617.6 GAP87369.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.25 GAP87369.1 - 0.08 12.3 0.1 0.48 9.7 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) fragilysinNterm PF16376.5 GAP87369.1 - 0.094 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin Flavi_DEAD PF07652.14 GAP87369.1 - 0.14 12.2 0.1 0.64 10.0 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 GAP87369.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Helicase DUF1664 PF07889.12 GAP87370.1 - 0.0025 17.8 4.6 0.66 10.0 0.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Nup54 PF13874.6 GAP87370.1 - 0.006 16.7 0.6 0.013 15.6 0.6 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 UPF0242 PF06785.11 GAP87370.1 - 0.017 15.2 0.2 0.026 14.6 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 GAP87370.1 - 0.04 13.9 3.3 0.74 9.8 3.3 2.2 1 1 1 2 2 2 0 Laminin Domain II Exonuc_VII_L PF02601.15 GAP87370.1 - 0.046 13.3 0.8 0.11 12.0 0.7 1.6 1 1 1 2 2 2 0 Exonuclease VII, large subunit Ferritin PF00210.24 GAP87370.1 - 0.048 13.6 0.1 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 Ferritin-like domain DUF2353 PF09789.9 GAP87370.1 - 0.069 12.5 1.7 0.16 11.3 1.8 1.5 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) GAS PF13851.6 GAP87370.1 - 0.079 12.3 1.4 3.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sec8_exocyst PF04048.14 GAP87370.1 - 0.22 11.4 3.6 3.6 7.5 0.3 2.9 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain COG5 PF10392.9 GAP87370.1 - 0.22 11.7 0.8 13 6.0 0.1 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 GAP87370.1 - 0.34 11.0 1.5 3.3 7.8 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 GAP87370.1 - 0.4 10.9 3.5 1.8 8.7 3.5 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 GAP87370.1 - 0.45 8.4 1.5 1.4 6.8 1.4 1.7 1 1 0 1 1 1 0 Prominin TolA_bind_tri PF16331.5 GAP87370.1 - 4.9 7.3 11.9 4.2 7.5 2.1 3.5 4 0 0 4 4 4 0 TolA binding protein trimerisation Peptidase_S9 PF00326.21 GAP87371.1 - 2.1e-54 184.2 0.0 4.1e-54 183.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 GAP87371.1 - 9e-06 25.5 0.0 3.5e-05 23.6 0.0 2.1 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat NuA4 PF09340.10 GAP87372.1 - 1.1e-24 86.0 0.5 1.1e-24 86.0 0.5 1.9 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 RR_TM4-6 PF06459.12 GAP87372.1 - 0.26 11.1 3.2 0.31 10.8 3.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NUDE_C PF04880.13 GAP87372.1 - 3.6 8.0 10.0 0.35 11.3 5.2 1.7 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region PWI PF01480.17 GAP87373.1 - 2.1e-31 108.0 0.1 3.8e-31 107.2 0.1 1.4 1 0 0 1 1 1 1 PWI domain Isochorismatase PF00857.20 GAP87374.1 - 3.7e-33 115.2 0.8 4.1e-33 115.0 0.8 1.0 1 0 0 1 1 1 1 Isochorismatase family FAA_hydrolase PF01557.18 GAP87376.1 - 1.1e-49 169.1 0.0 1.3e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ZU5 PF00791.20 GAP87376.1 - 0.094 13.1 0.0 0.22 11.9 0.0 1.6 2 0 0 2 2 2 0 ZU5 domain Glyco_hydro_18 PF00704.28 GAP87377.1 - 4.9e-65 220.3 0.0 7.1e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CAP_N PF01213.19 GAP87377.1 - 0.42 10.1 6.6 0.63 9.5 6.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CHORD PF04968.12 GAP87379.1 - 0.2 12.4 0.5 0.2 12.4 0.5 3.0 2 1 0 2 2 2 0 CHORD GP67 PF17634.2 GAP87379.1 - 3.5 8.1 8.4 2 8.9 0.4 2.3 2 0 0 2 2 2 0 Gene product 67 Glyco_hydro_61 PF03443.14 GAP87380.1 - 2.7e-30 105.8 0.0 3.4e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Prenylcys_lyase PF07156.14 GAP87381.1 - 7.7e-16 58.1 0.0 1.4e-15 57.3 0.0 1.3 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 GAP87381.1 - 2.6e-05 24.3 0.0 9.6e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP87381.1 - 4.1e-05 23.3 1.4 0.053 13.1 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP87381.1 - 0.00011 21.5 0.0 0.00024 20.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP87381.1 - 0.00042 20.3 0.1 0.0012 18.8 0.1 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAP87381.1 - 0.064 12.5 0.8 0.16 11.2 0.4 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP87381.1 - 0.092 12.0 0.2 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 GAP87381.1 - 0.19 10.4 0.2 0.32 9.7 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein PMT PF02366.18 GAP87382.1 - 5.4e-82 275.1 17.9 8.2e-82 274.5 17.9 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAP87382.1 - 4e-70 235.5 5.6 4e-70 235.5 5.6 2.8 3 1 1 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAP87382.1 - 5.3e-19 68.8 1.5 8.3e-19 68.2 1.5 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 GAP87382.1 - 0.0048 17.1 8.8 0.0048 17.1 8.8 3.2 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Glyco_hydro_7 PF00840.20 GAP87383.1 - 9.4e-118 393.7 17.3 2.8e-116 388.8 17.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 GAP87383.1 - 4.3e-13 49.0 11.7 4.3e-13 49.0 11.7 3.8 3 1 0 3 3 3 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.11 GAP87383.1 - 0.36 8.9 2.8 0.49 8.4 2.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_18 PF00704.28 GAP87384.1 - 4.1e-26 92.4 0.2 7.3e-26 91.6 0.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 GAP87384.1 - 4.5e-10 39.3 10.2 4.5e-10 39.3 10.2 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Sin_N PF04801.13 GAP87385.1 - 3.3e-22 79.3 0.0 9.3e-22 77.8 0.0 1.7 1 1 1 2 2 2 1 Sin-like protein conserved region PAT1 PF09770.9 GAP87386.1 - 0 1158.6 0.3 0 1158.3 0.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 HNH_2 PF13391.6 GAP87387.1 - 7.2e-15 54.9 0.0 3e-14 52.9 0.0 1.7 1 1 1 2 2 2 1 HNH endonuclease Glyco_transf_15 PF01793.16 GAP87388.1 - 4.4e-131 437.0 4.9 5.5e-131 436.6 4.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 GAP87389.1 - 1.1e-30 105.6 0.2 1.5e-30 105.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyl-CoA_dh_1 PF00441.24 GAP87390.1 - 3.8e-39 134.3 4.9 6e-39 133.6 4.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAP87390.1 - 8.4e-29 100.5 0.2 2.8e-28 98.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAP87390.1 - 2.1e-23 82.3 0.1 4.3e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAP87390.1 - 2.1e-16 60.4 1.0 3.3e-16 59.8 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 GAP87390.1 - 0.0018 18.0 0.0 0.0049 16.6 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 GAP87390.1 - 0.023 14.7 0.3 0.078 13.0 0.0 2.0 2 0 0 2 2 2 0 Staphylococcal AgrD protein Glyco_hydro_15 PF00723.21 GAP87391.1 - 3e-80 270.2 0.0 3.6e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 GAP87391.1 - 2.2e-17 62.7 0.0 5.6e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain Zip PF02535.22 GAP87392.1 - 1.6e-59 201.8 8.0 4.9e-58 196.9 8.0 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter SR-25 PF10500.9 GAP87392.1 - 1.5 8.4 8.9 2.2 7.8 8.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bul1_C PF04426.12 GAP87393.1 - 3.4e-07 30.0 0.5 6.4e-06 25.8 0.0 2.5 3 0 0 3 3 3 1 Bul1 C terminus Arrestin_N PF00339.29 GAP87393.1 - 7.4e-05 22.8 0.2 0.00062 19.9 0.2 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 GAP87393.1 - 0.0035 16.2 0.3 0.0035 16.2 0.3 2.2 2 1 1 3 3 3 1 Bul1 N terminus Transglut_core PF01841.19 GAP87394.1 - 4.8e-12 46.3 0.1 1.6e-11 44.7 0.1 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 GAP87394.1 - 0.012 16.6 0.1 0.041 14.9 0.1 2.0 1 1 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase CzcE PF16986.5 GAP87394.1 - 0.081 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal resistance protein CzcE MFS_1 PF07690.16 GAP87395.1 - 7.2e-40 137.0 64.7 1.5e-39 135.9 60.6 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP87395.1 - 1.4e-09 37.3 32.4 4.5e-09 35.7 9.9 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 GAP87395.1 - 3e-06 26.0 25.4 3e-06 26.0 25.4 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 GAP87396.1 - 1.1e-15 57.4 0.0 1.7e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP87396.1 - 8e-10 38.7 11.5 1.4e-09 37.9 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF932 PF06067.11 GAP87396.1 - 0.036 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Cep3 PF16846.5 GAP87396.1 - 0.1 11.0 0.1 0.15 10.5 0.1 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B DIOX_N PF14226.6 GAP87397.1 - 3.3e-24 85.9 0.0 6e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP87397.1 - 4.3e-21 75.3 0.0 1e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 GAP87398.1 - 2.1e-62 211.4 0.0 2.9e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PITH PF06201.13 GAP87401.1 - 6.1e-39 133.7 0.0 8.5e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 GAP87401.1 - 3.4e-27 94.4 0.0 5.1e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAP87401.1 - 8.4e-07 29.4 0.0 1.6e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAP87401.1 - 1.2e-05 25.6 0.0 0.00011 22.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 GAP87401.1 - 0.00025 20.5 0.0 0.0005 19.5 0.0 1.4 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 GAP87401.1 - 0.001 18.8 0.1 0.0018 18.0 0.1 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 GAP87401.1 - 0.029 14.1 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 GAP87401.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family HyaE PF07449.11 GAP87401.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DnaJ PF00226.31 GAP87402.1 - 7.2e-19 67.7 1.7 1.2e-18 67.0 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain Sigma70_ECF PF07638.11 GAP87402.1 - 0.0081 16.1 0.2 4.9 7.0 0.0 2.3 2 0 0 2 2 2 2 ECF sigma factor DUF456 PF04306.13 GAP87402.1 - 0.012 15.9 0.7 0.019 15.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 GAP87402.1 - 0.19 11.9 7.7 0.34 11.1 7.7 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PT-VENN PF04829.13 GAP87402.1 - 0.33 11.1 1.7 0.79 9.9 1.7 1.6 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif SARAF PF06682.12 GAP87402.1 - 0.8 9.3 4.8 1.6 8.3 4.8 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PRA1 PF03208.19 GAP87404.1 - 6.6e-34 116.6 0.8 9.8e-34 116.0 0.8 1.2 1 0 0 1 1 1 1 PRA1 family protein DUF3574 PF12098.8 GAP87405.1 - 0.033 14.0 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Wound_ind PF08186.11 GAP87406.1 - 0.16 12.4 0.2 0.32 11.4 0.2 1.4 1 0 0 1 1 1 0 Wound-inducible basic protein family MtlR PF05068.12 GAP87406.1 - 0.2 11.7 0.0 1.6 8.7 0.0 2.0 2 0 0 2 2 2 0 Mannitol repressor Pyridoxal_deC PF00282.19 GAP87408.1 - 8.6e-20 70.8 0.0 1.7e-12 46.8 0.0 3.0 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Glyco_hydro_3_C PF01915.22 GAP87409.1 - 1.1e-42 146.3 0.0 1.6e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAP87409.1 - 2.3e-37 129.1 0.0 3.5e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain WSC PF01822.19 GAP87409.1 - 1.3e-36 124.6 21.8 2.7e-20 72.3 7.4 2.4 2 0 0 2 2 2 2 WSC domain Fn3-like PF14310.6 GAP87409.1 - 6.1e-07 29.5 0.0 1.5e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_43 PF04616.14 GAP87410.1 - 1.1e-28 100.4 2.1 1.5e-28 100.0 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAP87410.1 - 8.8e-19 68.0 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain EBP PF05241.12 GAP87411.1 - 1.1e-55 187.9 6.8 1.3e-55 187.6 6.8 1.1 1 0 0 1 1 1 1 Emopamil binding protein Tim17 PF02466.19 GAP87412.1 - 8.9e-25 87.2 4.5 1.3e-24 86.7 4.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.9 GAP87413.1 - 1e-63 215.2 0.1 4.1e-62 209.9 0.0 3.0 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 GAP87413.1 - 0.00016 21.6 8.7 2 8.9 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 GAP87413.1 - 0.0087 16.4 1.0 0.36 11.3 0.7 3.9 4 1 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 GAP87413.1 - 0.093 12.8 0.0 20 5.2 0.0 3.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ThiD2 PF17792.1 GAP87413.1 - 0.16 12.4 0.4 5.8 7.4 0.1 2.8 2 0 0 2 2 2 0 ThiD2 family DUF1765 PF08578.10 GAP87413.1 - 0.4 11.2 2.5 4.1 7.9 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) Phosphodiest PF01663.22 GAP87414.1 - 7.1e-14 52.2 2.0 5e-09 36.2 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAP87414.1 - 0.00034 20.1 0.1 0.0033 16.8 0.0 2.2 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 GAP87414.1 - 0.0066 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Glyco_transf_22 PF03901.17 GAP87415.1 - 5.5e-59 200.5 25.8 6.7e-59 200.2 25.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pet100 PF09803.9 GAP87416.1 - 1.9e-20 73.2 0.3 2.3e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 Pet100 Nitr_red_bet_C PF14711.6 GAP87416.1 - 0.14 11.9 0.8 0.19 11.4 0.8 1.2 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal Transcrip_reg PF01709.20 GAP87417.1 - 2.2e-65 220.4 0.0 2.5e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator HEAT_2 PF13646.6 GAP87418.1 - 6.6e-09 36.0 3.8 2.5 8.6 0.6 7.3 6 1 1 7 7 7 2 HEAT repeats HEAT PF02985.22 GAP87418.1 - 1.7e-07 30.8 4.5 2.7 8.5 0.0 7.5 7 0 0 7 7 7 2 HEAT repeat V-ATPase_H_C PF11698.8 GAP87418.1 - 0.028 14.5 0.1 1.5 8.9 0.0 3.5 3 0 0 3 3 3 0 V-ATPase subunit H CLASP_N PF12348.8 GAP87418.1 - 0.046 13.3 4.6 3.5 7.1 0.1 3.9 3 0 0 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.6 GAP87418.1 - 0.055 14.0 9.8 6.6 7.3 0.1 6.6 6 1 1 7 7 7 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 GAP87418.1 - 0.072 13.7 0.0 41 4.9 0.0 4.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Whi5 PF08528.11 GAP87420.1 - 5.7e-10 38.6 0.1 8.9e-10 38.0 0.1 1.3 1 0 0 1 1 1 1 Whi5 like Ribosomal_L37 PF08561.10 GAP87421.1 - 7.8 7.0 7.2 11 6.6 2.2 3.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Peptidase_M18 PF02127.15 GAP87422.1 - 1.7e-53 182.0 0.0 1.9e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M18 PF02127.15 GAP87423.1 - 6.8e-110 367.8 0.4 3.6e-108 362.2 0.4 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 GAP87423.1 - 1.4e-07 30.9 0.2 8.9e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase HTH_3 PF01381.22 GAP87423.1 - 0.12 12.5 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix Xpo1 PF08389.12 GAP87424.1 - 3.4e-32 111.6 1.6 1.6e-30 106.2 0.0 3.5 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 GAP87424.1 - 0.0051 17.0 0.1 4.9 7.7 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat IBN_N PF03810.19 GAP87424.1 - 0.0094 15.9 0.0 0.057 13.3 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain EF-G-binding_N PF07299.11 GAP87424.1 - 0.018 15.5 0.2 1.9 9.0 0.0 3.9 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal FANCF PF11107.8 GAP87424.1 - 0.033 13.4 0.2 0.067 12.4 0.2 1.6 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) HEAT_EZ PF13513.6 GAP87424.1 - 0.041 14.4 0.5 65 4.2 0.1 4.0 3 0 0 3 3 3 0 HEAT-like repeat Occludin_ELL PF07303.13 GAP87424.1 - 0.19 12.5 0.0 0.61 10.9 0.0 1.9 1 0 0 1 1 1 0 Occludin homology domain DUF4844 PF16133.5 GAP87424.1 - 0.44 11.1 1.7 6.9 7.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) MtrF PF09472.10 GAP87429.1 - 0.56 9.6 4.9 0.93 8.9 0.3 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF5617 PF18493.1 GAP87430.1 - 0.14 12.3 0.1 20 5.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) RPAP1_N PF08621.10 GAP87430.1 - 0.27 11.0 2.1 0.66 9.8 2.1 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal ECH_1 PF00378.20 GAP87431.1 - 2.8e-29 102.2 0.0 3.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAP87431.1 - 2.3e-19 70.1 0.0 2.6e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PP2C PF00481.21 GAP87432.1 - 1.1e-34 120.3 0.0 1.6e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 GAP87432.1 - 0.014 15.3 0.0 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) Epimerase PF01370.21 GAP87433.1 - 1e-07 31.7 0.3 0.00029 20.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP87433.1 - 0.0024 17.8 2.3 0.0045 16.9 2.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 GAP87433.1 - 0.0038 17.7 0.1 0.013 15.9 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain PUF PF00806.19 GAP87434.1 - 8.9e-62 201.4 10.5 3.2e-08 32.8 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 GAP87434.1 - 0.068 13.0 0.3 48 3.8 0.0 3.9 4 1 1 5 5 5 0 Single Cache domain 2 SapB_2 PF03489.17 GAP87434.1 - 0.2 11.8 0.4 6.2 7.0 0.1 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 2 VPDSG-CTERM PF18205.1 GAP87435.1 - 1.5 8.7 7.2 3.6 7.5 7.2 1.6 1 0 0 1 1 1 0 VPDSG-CTERM motif DPBB_1 PF03330.18 GAP87436.1 - 1.3e-05 25.4 0.0 3.4e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Lytic transglycolase adh_short PF00106.25 GAP87437.1 - 1.2e-34 119.6 0.0 1.4e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87437.1 - 1.9e-30 106.2 0.0 2.5e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87437.1 - 1.7e-10 41.1 0.1 2.7e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 KR domain ThiF PF00899.21 GAP87437.1 - 0.033 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 ThiF family Eno-Rase_NADH_b PF12242.8 GAP87437.1 - 0.044 13.6 0.2 4.7 7.1 0.1 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 GAP87437.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Phosphodiest PF01663.22 GAP87438.1 - 1.1e-14 54.8 0.2 2.1e-14 53.9 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAP87438.1 - 7.5e-05 22.3 0.1 0.00012 21.5 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 GAP87438.1 - 0.00015 21.2 0.2 0.00031 20.2 0.2 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 GAP87438.1 - 0.37 10.8 0.9 13 5.8 0.1 2.3 2 0 0 2 2 2 0 PglZ domain DUF5543 PF17697.1 GAP87439.1 - 0.07 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5543) Bac_chlorC PF02043.17 GAP87439.1 - 0.1 12.6 0.0 0.71 9.9 0.1 2.1 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein ABC_membrane PF00664.23 GAP87440.1 - 3.8e-100 335.0 41.6 2.4e-51 175.0 13.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAP87440.1 - 4.8e-68 227.9 0.0 1.1e-32 113.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAP87440.1 - 1.1e-13 51.1 0.0 6e-05 22.6 0.0 3.6 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAP87440.1 - 2.9e-08 34.3 1.1 0.00091 19.6 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 GAP87440.1 - 5.5e-07 29.2 2.0 0.002 17.8 0.2 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAP87440.1 - 5.7e-06 26.3 0.0 0.1 12.5 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase ABC_ATPase PF09818.9 GAP87440.1 - 1.1e-05 24.5 3.9 0.036 12.9 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 GAP87440.1 - 0.00016 21.9 1.8 0.42 10.9 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAP87440.1 - 0.00018 21.1 0.1 0.3 10.7 0.1 3.0 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 GAP87440.1 - 0.00037 20.3 0.0 0.98 9.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 GAP87440.1 - 0.00041 20.8 1.5 10 6.5 0.0 4.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 GAP87440.1 - 0.00044 20.2 0.6 0.83 9.4 0.0 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 GAP87440.1 - 0.00064 19.5 2.5 0.97 9.1 0.1 3.6 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.6 GAP87440.1 - 0.00066 20.2 0.1 0.77 10.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 GAP87440.1 - 0.0014 18.9 2.1 1.5 9.1 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 GAP87440.1 - 0.0028 17.8 0.9 1.3 9.1 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain Zeta_toxin PF06414.12 GAP87440.1 - 0.0029 16.9 0.0 1.9 7.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin G-alpha PF00503.20 GAP87440.1 - 0.0057 15.9 0.0 2.7 7.0 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 GAP87440.1 - 0.0073 16.6 0.6 0.62 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 GAP87440.1 - 0.013 15.5 0.3 12 5.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAP87440.1 - 0.025 14.7 1.0 10 6.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 GAP87440.1 - 0.032 13.7 0.0 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 GAP87440.1 - 0.039 14.5 0.1 14 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain TMIE PF16038.5 GAP87440.1 - 0.047 13.5 0.2 0.53 10.2 0.0 2.6 2 0 0 2 2 2 0 TMIE protein SRP54 PF00448.22 GAP87440.1 - 0.056 13.1 0.3 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 GAP87440.1 - 0.1 12.0 0.4 4.5 6.6 0.1 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.15 GAP87440.1 - 0.1 12.5 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 GAP87440.1 - 0.17 11.6 0.3 9.6 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 GAP87440.1 - 0.25 11.4 0.7 20 5.3 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase SARAF PF06682.12 GAP87441.1 - 6.9e-94 315.2 4.5 1.2e-93 314.4 4.5 1.3 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis BRE1 PF08647.11 GAP87442.1 - 6.3e-23 80.7 8.2 6.3e-23 80.7 8.2 7.2 3 2 1 5 5 5 2 BRE1 E3 ubiquitin ligase zf-RING_UBOX PF13445.6 GAP87442.1 - 1.2e-08 34.8 4.2 2.9e-08 33.6 4.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAP87442.1 - 2.5e-08 33.6 7.3 3.9e-08 33.0 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAP87442.1 - 3.8e-08 33.1 6.3 6.5e-08 32.3 6.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAP87442.1 - 2.7e-07 30.3 7.5 4.6e-07 29.6 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP87442.1 - 4.3e-07 30.1 7.1 7.4e-07 29.4 7.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAP87442.1 - 1.6e-06 27.9 7.6 2.9e-06 27.1 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP87442.1 - 3.1e-06 27.0 9.1 5.6e-06 26.2 9.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAP87442.1 - 0.0066 16.6 4.8 0.013 15.7 4.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_PEP_C PF04513.12 GAP87442.1 - 0.0096 16.0 2.4 0.0096 16.0 2.4 5.4 3 3 2 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus bZIP_1 PF00170.21 GAP87442.1 - 0.022 14.9 0.8 0.022 14.9 0.8 8.9 7 1 1 9 9 8 0 bZIP transcription factor zf-RING_6 PF14835.6 GAP87442.1 - 0.024 14.5 2.8 0.049 13.5 2.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 GAP87442.1 - 0.031 14.1 6.8 0.15 11.9 7.0 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 GAP87442.1 - 0.033 14.3 5.5 0.066 13.3 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_10 PF16685.5 GAP87442.1 - 0.034 14.3 4.2 0.1 12.8 4.2 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 TRAF6_Z2 PF18048.1 GAP87442.1 - 0.093 12.8 0.1 0.26 11.4 0.1 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 zf-ribbon_3 PF13248.6 GAP87442.1 - 0.094 12.2 1.3 1.4 8.5 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-rbx1 PF12678.7 GAP87442.1 - 0.12 12.6 6.0 0.48 10.8 6.0 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF4677 PF15726.5 GAP87442.1 - 0.21 11.8 1.4 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) FYVE PF01363.21 GAP87442.1 - 0.27 11.4 11.1 2.8 8.1 11.1 2.3 1 1 0 1 1 1 0 FYVE zinc finger zf-C2HE PF16278.5 GAP87442.1 - 0.47 11.0 3.2 1.1 9.7 0.5 3.3 2 0 0 2 2 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 GAP87442.1 - 0.48 10.9 4.5 5.5 7.6 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP87442.1 - 0.68 10.9 4.0 21 6.3 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 GAP87442.1 - 0.91 10.1 5.4 13 6.4 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-FCS PF06467.14 GAP87442.1 - 0.97 9.4 7.0 2.3 8.2 2.5 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FlaC_arch PF05377.11 GAP87442.1 - 1 9.8 0.0 1 9.8 0.0 8.9 7 3 4 11 11 10 0 Flagella accessory protein C (FlaC) DZR PF12773.7 GAP87442.1 - 2.4 8.3 5.8 5.2 7.2 5.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon MbeD_MobD PF04899.12 GAP87442.1 - 2.4 8.3 26.7 0.78 9.9 0.1 7.3 5 3 3 8 8 8 0 MbeD/MobD like zf-C2H2_jaz PF12171.8 GAP87442.1 - 8.5 6.8 11.4 17 5.8 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Myb_DNA-bind_7 PF15963.5 GAP87443.1 - 5.1e-24 84.0 2.1 1.1e-23 82.9 2.1 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 GAP87443.1 - 2.6e-07 30.7 1.1 5.7e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP87443.1 - 0.00095 19.4 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DTHCT PF08070.11 GAP87443.1 - 7.2 7.4 19.8 0.61 10.9 8.4 3.5 3 0 0 3 3 3 0 DTHCT (NUC029) region XPC-binding PF09280.11 GAP87444.1 - 2e-25 88.3 16.0 4e-25 87.3 16.0 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 GAP87444.1 - 5.7e-23 80.4 9.8 3e-13 49.4 0.5 2.9 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.23 GAP87444.1 - 9.9e-20 70.1 0.5 1.7e-19 69.3 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAP87444.1 - 1.7e-07 30.9 1.3 3.1e-07 30.1 1.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 GAP87444.1 - 0.00036 20.3 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain DUF2407 PF10302.9 GAP87444.1 - 0.0034 17.9 0.0 0.0073 16.8 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAP87444.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAP87444.1 - 0.022 15.1 0.2 0.043 14.2 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain CUE PF02845.16 GAP87444.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 CUE domain DUF1421 PF07223.11 GAP87444.1 - 0.048 13.5 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 UBA-like domain (DUF1421) ARS2 PF04959.13 GAP87444.1 - 0.052 13.9 4.7 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Arsenite-resistance protein 2 MCM_N PF14551.6 GAP87444.1 - 0.12 13.0 0.5 0.31 11.6 0.2 1.8 2 0 0 2 2 1 0 MCM N-terminal domain MSA-2c PF12238.8 GAP87444.1 - 0.12 12.3 12.7 0.037 14.0 3.5 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c TFIIA PF03153.13 GAP87444.1 - 0.32 10.9 9.2 0.49 10.3 9.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rib_recp_KP_reg PF05104.12 GAP87444.1 - 8.1 7.5 21.4 3.6 8.6 7.2 2.2 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region PrsW-protease PF13367.6 GAP87445.1 - 0.058 12.8 4.1 0.14 11.6 4.2 1.5 1 1 0 1 1 1 0 PrsW family intramembrane metalloprotease Aminotran_3 PF00202.21 GAP87447.1 - 3.7e-120 401.3 0.0 4.3e-120 401.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAP87447.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SRI PF08236.11 GAP87448.1 - 6.8e-22 77.4 11.3 1.7e-21 76.2 11.3 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 GAP87448.1 - 2.9e-17 63.6 0.2 2.9e-17 63.6 0.2 4.2 3 2 0 3 3 3 1 SET domain AWS PF17907.1 GAP87448.1 - 1.2e-12 47.7 13.6 1.2e-12 47.7 13.6 2.6 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 GAP87448.1 - 7.6e-05 22.7 1.6 0.00012 22.0 0.1 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.26 GAP87448.1 - 0.0058 16.7 2.0 0.016 15.3 2.0 1.8 1 0 0 1 1 1 1 WW domain HHH_9 PF17674.1 GAP87448.1 - 1.2 10.1 3.7 0.92 10.5 0.1 2.7 3 0 0 3 3 3 0 HHH domain DUF445 PF04286.12 GAP87448.1 - 1.3 8.7 7.9 4.4 7.0 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) AT_hook PF02178.19 GAP87449.1 - 8.2 6.7 10.2 0.13 12.2 2.1 2.6 2 0 0 2 2 2 0 AT hook motif DUF2431 PF10354.9 GAP87450.1 - 4.5e-67 225.5 0.0 6.2e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) SPX PF03105.19 GAP87450.1 - 0.028 14.3 4.3 0.035 14.0 4.3 1.2 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 GAP87450.1 - 0.17 11.5 18.1 0.28 10.7 18.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 GAP87450.1 - 0.54 8.7 4.5 0.66 8.5 4.5 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 GAP87450.1 - 0.76 8.6 3.8 0.99 8.2 3.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC106 PF15794.5 GAP87450.1 - 9.9 5.8 7.4 17 5.0 7.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 ThiF PF00899.21 GAP87452.1 - 2.9e-28 98.9 0.0 4.3e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family eIF-6 PF01912.18 GAP87454.1 - 2.4e-80 268.6 0.7 3.5e-80 268.1 0.7 1.2 1 0 0 1 1 1 1 eIF-6 family HupE_UreJ PF04955.12 GAP87454.1 - 0.16 11.4 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 HupE / UreJ protein ERM PF00769.19 GAP87455.1 - 0.035 13.9 19.3 0.053 13.3 19.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SKA1 PF07160.12 GAP87455.1 - 0.038 13.9 6.8 0.063 13.1 6.8 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Exonuc_VII_L PF02601.15 GAP87455.1 - 0.14 11.7 3.8 0.21 11.1 3.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PIEZO PF15917.5 GAP87455.1 - 0.17 11.3 8.5 0.36 10.3 8.0 1.7 2 0 0 2 2 2 0 Piezo YscO PF07321.12 GAP87455.1 - 0.41 10.6 23.4 1.9 8.4 21.5 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO Spc7 PF08317.11 GAP87455.1 - 0.56 9.0 12.6 0.85 8.4 12.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 GAP87455.1 - 0.59 9.5 14.8 0.87 9.0 14.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 OmpH PF03938.14 GAP87455.1 - 1.9 8.8 15.3 3.6 7.9 15.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Nup88 PF10168.9 GAP87455.1 - 3.8 5.2 8.5 5.3 4.7 8.5 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF3138 PF11336.8 GAP87455.1 - 9 4.8 7.6 0.26 9.9 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) NDUF_B12 PF08122.12 GAP87456.1 - 6.2e-24 83.8 0.8 1.1e-23 83.0 0.8 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.20 GAP87457.1 - 4.1e-23 82.1 0.7 4.1e-11 42.6 0.0 2.9 3 0 0 3 3 3 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 GAP87457.1 - 0.06 14.0 0.0 2.5 8.8 0.0 2.6 3 0 0 3 3 3 0 RFX DNA-binding domain Ndc1_Nup PF09531.10 GAP87457.1 - 0.2 10.3 0.7 0.29 9.8 0.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-3_zeta PF05091.12 GAP87457.1 - 0.34 9.8 2.4 0.49 9.3 2.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SUIM_assoc PF16619.5 GAP87457.1 - 1.3 9.2 13.1 4 7.6 13.1 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CLTH PF10607.9 GAP87458.1 - 2.4e-31 108.6 0.0 4.5e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 GAP87458.1 - 0.00011 22.0 0.0 0.00026 20.8 0.0 1.7 1 0 0 1 1 1 1 LisH HLH PF00010.26 GAP87459.1 - 1.8e-13 50.2 0.7 5.2e-13 48.7 0.7 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT1_C PF12205.8 GAP87459.1 - 0.014 15.5 1.4 0.067 13.3 1.4 2.1 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Pox_A30L_A26L PF06086.12 GAP87459.1 - 0.22 11.2 0.0 0.32 10.7 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein eIF-5_eIF-2B PF01873.17 GAP87460.1 - 5.9e-40 135.8 0.0 2e-39 134.1 0.0 1.9 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 GAP87460.1 - 1.7e-23 82.5 0.9 1.1e-22 79.9 0.2 2.6 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Pns11_12 PF17464.2 GAP87460.1 - 0.039 13.7 2.4 0.071 12.8 2.4 1.3 1 0 0 1 1 1 0 Non-structural protein 11 and 12 CoaE PF01121.20 GAP87462.1 - 1e-42 145.9 0.0 2.2e-42 144.8 0.0 1.5 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 GAP87462.1 - 0.028 15.0 0.1 0.2 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain GARS_A PF01071.19 GAP87463.1 - 4.5e-84 281.1 0.0 7.5e-84 280.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 GAP87463.1 - 9.3e-33 112.9 0.0 2.7e-32 111.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 GAP87463.1 - 2.8e-32 112.0 0.0 4.4e-31 108.1 0.0 2.5 3 0 0 3 3 3 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 GAP87463.1 - 5.6e-28 97.1 1.3 1.3e-27 95.8 1.3 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 GAP87463.1 - 1.8e-14 54.2 2.9 6.6e-14 52.3 2.9 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 GAP87463.1 - 0.0022 17.6 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 GAP87463.1 - 0.0032 17.0 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 GAP87463.1 - 0.013 15.6 0.0 0.043 13.9 0.0 2.0 2 1 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 GAP87463.1 - 0.11 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Lipase_3 PF01764.25 GAP87464.1 - 2.6e-07 30.6 0.0 7.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 GAP87464.1 - 0.002 17.4 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 GAP87464.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family VPS9 PF02204.18 GAP87465.1 - 1.4e-26 92.7 0.1 2.9e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 GAP87465.1 - 0.00015 22.0 0.5 0.00048 20.4 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CH PF00307.31 GAP87466.1 - 6.8e-47 158.2 0.0 3.6e-23 81.8 0.0 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 GAP87466.1 - 2e-22 79.1 0.1 6.6e-22 77.4 0.0 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 GAP87466.1 - 1.9e-12 46.8 0.1 1.9e-06 27.6 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 GAP87466.1 - 0.00015 21.4 0.1 0.00074 19.3 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 GAP87466.1 - 0.00052 20.4 4.3 0.00071 20.0 2.3 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 GAP87466.1 - 0.0011 18.7 0.7 0.0059 16.4 0.1 2.5 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 GAP87466.1 - 0.0036 16.8 0.3 0.03 13.8 0.0 2.4 2 0 0 2 2 2 1 EF hand Spectrin PF00435.21 GAP87466.1 - 0.15 12.6 4.9 4.8 7.7 0.0 2.7 2 0 0 2 2 2 0 Spectrin repeat SRR1 PF07985.12 GAP87467.1 - 0.0012 18.8 0.1 0.0058 16.6 0.0 2.2 3 0 0 3 3 3 1 SRR1 FAD-oxidase_C PF02913.19 GAP87468.1 - 1e-64 218.6 0.0 1.3e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAP87468.1 - 3e-36 124.2 0.9 5.7e-36 123.3 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain Ribosomal_L23 PF00276.20 GAP87469.1 - 9.1e-17 61.2 0.7 1.8e-16 60.2 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 GAP87469.1 - 2.4e-11 43.6 13.3 3e-11 43.4 9.0 2.7 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Phage_lysozyme PF00959.19 GAP87469.1 - 0.031 14.7 0.1 0.97 9.9 0.0 2.1 2 0 0 2 2 2 0 Phage lysozyme DUF2608 PF11019.8 GAP87469.1 - 0.063 12.8 0.2 0.08 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Bmt2 PF11968.8 GAP87470.1 - 1.7e-85 286.3 0.0 2.3e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 HAD_2 PF13419.6 GAP87471.1 - 0.0029 17.7 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP87471.1 - 0.012 15.9 0.0 0.053 13.8 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP87471.1 - 0.056 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Pkinase PF00069.25 GAP87472.1 - 8.6e-56 189.2 0.0 1.3e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87472.1 - 7.2e-33 114.0 0.0 9.9e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP87472.1 - 1.3e-12 47.6 0.0 2.1e-09 37.2 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 GAP87472.1 - 0.0071 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP87472.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAN_4 PF14295.6 GAP87473.1 - 7.2e-05 22.6 1.7 0.00013 21.7 1.7 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 GAP87473.1 - 0.00082 19.3 0.2 0.0022 17.9 0.2 1.7 1 0 0 1 1 1 1 PAN domain Rhabdo_glycop PF00974.18 GAP87473.1 - 0.051 12.0 0.8 0.38 9.2 0.2 2.0 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein SpoIIIAH PF12685.7 GAP87473.1 - 0.14 12.0 0.5 0.19 11.5 0.5 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein LCM PF04072.14 GAP87474.1 - 5.5e-14 52.5 0.0 9.3e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kinetochor_Ybp2 PF08568.10 GAP87475.1 - 1.2e-86 291.7 0.0 1.6e-86 291.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HET PF06985.11 GAP87476.1 - 1e-23 84.3 0.3 3.6e-23 82.5 0.3 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 GAP87477.1 - 7.9e-33 114.0 0.1 9.2e-33 113.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP87477.1 - 2.9e-16 59.5 0.1 3.5e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.25 GAP87478.1 - 3.7e-15 55.9 0.0 4.7e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP87478.1 - 3.6e-12 46.5 0.1 5.8e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 GAP87478.1 - 4.7e-09 36.2 0.1 6.5e-09 35.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAP87478.1 - 0.0061 16.1 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 GAP87478.1 - 0.11 13.0 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GDP_Man_Dehyd PF16363.5 GAP87478.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 GAP87478.1 - 0.25 10.3 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PRAS PF15798.5 GAP87479.1 - 0.084 13.5 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Proline-rich AKT1 substrate 1 Cellulase PF00150.18 GAP87480.1 - 5.6e-48 163.8 0.0 7.9e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Man-6-P_recep PF02157.15 GAP87481.1 - 3.8e-19 68.8 0.0 8e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 GAP87481.1 - 4.9e-12 46.3 0.1 1.3e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 GAP87481.1 - 3e-08 33.8 0.5 6.2e-05 23.1 0.1 2.5 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat RGS12_us1 PF16613.5 GAP87481.1 - 0.0058 16.9 1.7 0.012 15.9 1.7 1.5 1 0 0 1 1 1 1 Unstructured region of RGS12 CDC45 PF02724.14 GAP87481.1 - 0.023 13.0 11.5 0.029 12.7 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 GAP87481.1 - 0.053 12.9 19.5 0.071 12.5 19.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GAP87481.1 - 0.32 9.1 20.9 0.45 8.7 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2842 PF11003.8 GAP87481.1 - 0.45 10.8 4.4 1 9.7 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) Mpp10 PF04006.12 GAP87481.1 - 1.6 7.1 18.8 2 6.7 18.8 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 GAP87481.1 - 9.6 4.9 6.4 12 4.5 6.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Glyco_transf_25 PF01755.17 GAP87482.1 - 8.7e-05 22.5 0.0 0.00092 19.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) SKG6 PF08693.10 GAP87483.1 - 0.00053 19.3 2.6 0.00053 19.3 2.6 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rax2 PF12768.7 GAP87483.1 - 0.0065 16.0 0.0 0.0096 15.4 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity EphA2_TM PF14575.6 GAP87483.1 - 0.15 13.0 0.0 3.8 8.5 0.0 2.7 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain AAA PF00004.29 GAP87484.1 - 3.9e-16 59.7 0.0 5.9e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Citrate_synt PF00285.21 GAP87485.1 - 2.4e-121 405.2 0.0 3.1e-121 404.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain FAM184 PF15665.5 GAP87486.1 - 0.015 15.1 0.1 0.015 15.1 0.1 3.8 3 1 0 4 4 4 0 Family with sequence similarity 184, A and B Metal_resist PF13801.6 GAP87486.1 - 0.018 15.3 0.8 4.3 7.5 0.0 3.7 4 1 0 4 4 4 0 Heavy-metal resistance Apolipoprotein PF01442.18 GAP87486.1 - 0.071 13.0 17.3 0.81 9.5 1.9 4.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1772 PF08592.11 GAP87486.1 - 0.074 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) RasGAP PF00616.19 GAP87486.1 - 0.24 11.1 2.9 0.2 11.3 0.1 2.1 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase DUF2939 PF11159.8 GAP87486.1 - 0.37 11.2 1.7 7 7.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) Rep_fac-A_C PF08646.10 GAP87486.1 - 0.68 9.7 4.3 0.7 9.6 0.4 2.9 3 1 1 4 4 4 0 Replication factor-A C terminal domain YtxH PF12732.7 GAP87486.1 - 2.5 8.7 30.8 20 5.8 3.3 5.6 2 1 0 2 2 2 0 YtxH-like protein EAP30 PF04157.16 GAP87486.1 - 3.7 6.8 7.9 4.2 6.6 1.3 3.0 3 0 0 3 3 3 0 EAP30/Vps36 family GTP_EFTU PF00009.27 GAP87488.1 - 2.4e-18 66.4 0.1 5.1e-18 65.3 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAP87488.1 - 1.5e-08 34.9 1.3 4.1e-08 33.5 0.8 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 GAP87488.1 - 6.9e-05 23.1 0.0 0.00017 21.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain RsgA_GTPase PF03193.16 GAP87488.1 - 0.0016 18.4 0.5 0.69 9.8 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAP87488.1 - 0.0017 18.4 0.1 0.0057 16.7 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 GAP87488.1 - 0.04 13.7 0.4 2.4 7.9 0.1 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 GAP87488.1 - 0.082 13.0 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 Dynamin family p450 PF00067.22 GAP87489.1 - 1.1e-70 238.7 0.0 1.4e-70 238.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1971 PF09313.11 GAP87489.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) TetR_C_12 PF16914.5 GAP87489.1 - 0.068 13.3 0.7 0.43 10.7 0.2 2.1 2 0 0 2 2 2 0 Bacterial transcriptional repressor C-terminal SDH_alpha PF03313.15 GAP87490.1 - 9.9e-100 333.5 0.7 1.3e-99 333.2 0.7 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 GAP87490.1 - 3.7e-54 183.3 0.0 8.1e-54 182.2 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain LDB19 PF13002.7 GAP87491.1 - 9.7e-35 120.0 0.2 2.4e-34 118.7 0.1 1.7 1 1 0 1 1 1 1 Arrestin_N terminal like DUF4606 PF15379.6 GAP87491.1 - 0.021 15.1 1.5 0.06 13.6 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) CCDC53 PF10152.9 GAP87491.1 - 4.9 7.6 8.6 2.3 8.6 0.5 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF2502 PF10697.9 GAP87492.1 - 0.077 13.4 0.3 0.15 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) SQS_PSY PF00494.19 GAP87494.1 - 6.3e-56 189.8 0.0 8e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.23 GAP87495.1 - 1.9e-75 253.8 0.0 2.6e-75 253.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 GAP87495.1 - 1.2e-22 79.7 0.0 2.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 GAP87495.1 - 6.8e-15 55.4 0.0 1.7e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP87495.1 - 1.7e-05 24.9 0.0 4.5e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 GAP87495.1 - 0.00015 21.6 10.5 0.00033 20.5 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP87495.1 - 0.00052 19.8 7.5 0.0014 18.4 7.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.6 GAP87495.1 - 0.0012 18.6 0.1 0.028 14.2 0.0 2.8 2 0 0 2 2 2 1 UBA-like domain zf-RING_2 PF13639.6 GAP87495.1 - 0.0027 18.0 11.4 0.0075 16.6 11.4 1.8 1 0 0 1 1 1 1 Ring finger domain PLU-1 PF08429.11 GAP87495.1 - 0.02 14.1 0.6 0.041 13.1 0.6 1.4 1 0 0 1 1 1 0 PLU-1-like protein zf-C3HC4_3 PF13920.6 GAP87495.1 - 0.06 13.2 12.5 0.013 15.3 8.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP87495.1 - 0.063 13.3 9.5 0.17 11.9 9.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Tenui_NS3 PF05310.12 GAP87495.1 - 0.24 11.5 0.8 3.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Tenuivirus movement protein zf-RING_5 PF14634.6 GAP87495.1 - 0.93 9.5 12.8 0.91 9.5 9.3 2.7 2 1 1 3 3 3 0 zinc-RING finger domain TRAM_LAG1_CLN8 PF03798.16 GAP87496.1 - 1.5e-36 126.0 8.1 1.5e-36 126.0 8.1 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 GAP87496.1 - 1.1e-16 60.2 0.0 2.7e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein MFS_1 PF07690.16 GAP87497.1 - 4e-35 121.4 16.8 1.3e-17 63.8 4.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP87497.1 - 2.8e-07 29.8 11.8 0.00042 19.3 6.2 3.4 4 0 0 4 4 4 2 Sugar (and other) transporter MFS_5 PF05631.14 GAP87497.1 - 7.3e-06 25.1 1.7 9.4e-06 24.8 0.7 1.7 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_2 PF13347.6 GAP87497.1 - 0.00031 19.4 23.9 0.084 11.4 10.7 3.4 2 2 1 3 3 3 3 MFS/sugar transport protein OATP PF03137.20 GAP87497.1 - 0.0065 14.8 11.2 0.0097 14.2 0.1 2.5 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 GAP87497.1 - 0.019 13.8 14.3 0.02 13.8 6.0 3.1 2 1 0 2 2 2 0 MFS_1 like family MFS_3 PF05977.13 GAP87497.1 - 0.52 8.6 10.2 0.8 8.0 1.9 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Ank_2 PF12796.7 GAP87498.1 - 1.4e-44 150.6 0.0 1.1e-07 32.3 0.0 8.1 5 2 1 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP87498.1 - 3.8e-32 106.7 2.4 3.7e-05 23.8 0.0 11.8 13 0 0 13 13 13 5 Ankyrin repeat Ank_4 PF13637.6 GAP87498.1 - 7.4e-31 106.1 3.9 0.001 19.6 0.0 10.5 7 2 5 12 12 12 7 Ankyrin repeats (many copies) Pkinase PF00069.25 GAP87498.1 - 6e-26 91.4 0.0 9.9e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 GAP87498.1 - 1.6e-24 85.6 2.8 2e-05 24.8 0.0 7.6 6 1 2 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 GAP87498.1 - 2.2e-22 78.4 12.9 0.0002 21.7 0.0 9.8 11 1 1 12 12 12 5 Ankyrin repeat Pkinase_Tyr PF07714.17 GAP87498.1 - 3.4e-18 65.9 0.0 5.7e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP87498.1 - 0.0042 16.5 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 GAP87498.1 - 0.094 11.7 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HeLo PF14479.6 GAP87499.1 - 3.7e-15 56.3 0.1 7.5e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation P5CR_dimer PF14748.6 GAP87500.1 - 1.2e-36 125.1 0.7 1.2e-36 125.1 0.7 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAP87500.1 - 2e-17 63.6 1.1 4.1e-17 62.5 0.3 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAP87500.1 - 0.043 14.0 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaE PF06610.13 GAP87500.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 L-alanine exporter NAD_Gly3P_dh_N PF01210.23 GAP87500.1 - 0.16 11.9 1.9 0.3 11.1 0.5 2.1 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_25 PF13649.6 GAP87501.1 - 0.0002 22.0 0.0 0.00041 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP87501.1 - 0.028 15.1 0.0 0.058 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 GAP87503.1 - 1.4e-17 63.7 17.5 2.1e-17 63.1 17.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 GAP87504.1 - 1.8e-42 145.7 0.0 2.7e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Bax1-I PF01027.20 GAP87504.1 - 0.2 11.5 10.5 0.33 10.7 10.5 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DEAD PF00270.29 GAP87505.1 - 3.5e-35 121.3 0.2 5.2e-35 120.8 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP87505.1 - 2.5e-28 98.6 0.0 5.7e-27 94.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP87505.1 - 1.9e-07 31.3 0.0 3.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FAD_binding_3 PF01494.19 GAP87506.1 - 5e-10 39.2 2.0 2.3e-07 30.4 0.4 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAP87506.1 - 0.00015 21.4 1.6 0.00077 19.1 0.8 2.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase SE PF08491.10 GAP87506.1 - 0.012 14.7 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.6 GAP87506.1 - 0.016 15.4 2.2 0.018 15.3 0.1 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAP87506.1 - 0.077 11.8 0.2 8.6 5.1 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase Anillin PF08174.11 GAP87507.1 - 1e-11 45.4 0.0 3.6e-11 43.7 0.0 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 GAP87507.1 - 1.7e-08 34.9 0.0 5.1e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 PH domain POB3_N PF17292.2 GAP87508.1 - 8.2e-32 109.5 0.5 7e-28 96.9 0.1 3.0 3 0 0 3 3 3 2 POB3-like N-terminal PH domain SSrecog PF03531.14 GAP87508.1 - 6.8e-31 106.0 0.3 3.9e-30 103.6 0.0 2.4 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 GAP87508.1 - 9.7e-24 83.6 0.0 1.3e-22 80.0 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Na_trans_assoc PF06512.13 GAP87508.1 - 9.6 6.4 16.2 2 8.6 12.2 1.8 2 1 0 2 2 2 0 Sodium ion transport-associated HET PF06985.11 GAP87509.1 - 8.3e-33 113.8 0.0 1.3e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SnoaL PF07366.12 GAP87510.1 - 0.026 14.3 0.0 1.5 8.7 0.0 2.1 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase MOLO1 PF17175.4 GAP87510.1 - 0.086 13.0 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Modulator of levamisole receptor-1 DUF1899 PF08953.11 GAP87511.1 - 1.1e-35 121.3 0.1 1.9e-35 120.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 GAP87511.1 - 2.6e-20 72.0 0.1 5.4e-20 71.0 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 GAP87511.1 - 1.2e-15 57.6 5.0 1.8e-05 25.4 0.3 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP87511.1 - 1.8e-07 31.4 0.0 0.0031 17.8 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP87511.1 - 0.00026 19.8 0.1 0.04 12.6 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 GAP87511.1 - 0.0046 16.0 0.0 0.023 13.7 0.0 2.0 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAP87511.1 - 0.018 14.9 0.0 0.13 12.2 0.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A SOG2 PF10428.9 GAP87511.1 - 0.051 12.8 5.0 0.07 12.3 5.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SlyX PF04102.12 GAP87511.1 - 0.29 11.8 2.1 0.44 11.2 0.5 2.1 2 1 0 2 2 2 0 SlyX DUF5446 PF17522.2 GAP87511.1 - 4.6 7.5 5.1 11 6.3 0.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5446) His_biosynth PF00977.21 GAP87512.1 - 9.5e-34 116.8 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF4602 PF15375.6 GAP87513.1 - 1.4e-11 44.9 0.1 1.4e-11 44.9 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4602) Nop25 PF09805.9 GAP87513.1 - 3.4 8.1 9.5 0.26 11.8 3.6 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Glyco_transf_15 PF01793.16 GAP87514.1 - 8.4e-95 317.7 6.3 8.9e-94 314.4 6.3 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4604 PF15377.6 GAP87516.1 - 1.1e-16 61.7 4.1 3e-16 60.3 4.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Chs7 PF12271.8 GAP87517.1 - 1.3e-118 395.6 14.3 1.5e-118 395.4 14.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Alginate_exp PF13372.6 GAP87519.1 - 0.054 12.2 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Alginate export RicinB_lectin_2 PF14200.6 GAP87520.1 - 2.7e-10 40.8 0.0 8.6e-05 23.2 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 GAP87520.1 - 0.02 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Ricin_B_lectin PF00652.22 GAP87520.1 - 0.027 14.7 0.1 0.088 13.1 0.1 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF3433 PF11915.8 GAP87522.1 - 1.4e-28 99.1 13.5 1.5e-15 57.4 4.6 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) HRG PF16954.5 GAP87522.1 - 0.15 12.5 0.2 0.15 12.5 0.2 3.3 5 0 0 5 5 5 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Beta-lactamase PF00144.24 GAP87523.1 - 3.7e-25 88.9 0.0 2.1e-24 86.4 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 GAP87523.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase MGC-24 PF05283.11 GAP87525.1 - 0.00032 21.2 1.9 0.00072 20.0 1.9 1.6 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin15 PF15672.5 GAP87525.1 - 0.0063 16.0 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 Alpha_GJ PF03229.13 GAP87525.1 - 0.033 14.8 5.9 0.059 13.9 5.9 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Adeno_E3_CR2 PF02439.15 GAP87525.1 - 0.22 11.3 0.2 0.45 10.3 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 tRNA-synt_2d PF01409.20 GAP87526.1 - 2.4e-82 276.1 0.0 3.2e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 GAP87526.1 - 5.8e-14 52.1 0.1 1.3e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 GAP87526.1 - 1.1e-05 24.7 0.1 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 GAP87526.1 - 3.9e-05 23.2 0.1 0.093 12.2 0.0 2.9 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 GAP87526.1 - 0.05 13.6 0.4 0.2 11.7 0.4 2.1 1 1 0 1 1 1 0 PheRS DNA binding domain 2 Glyco_hydro_3 PF00933.21 GAP87527.1 - 2e-42 145.7 0.0 3.2e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAP87527.1 - 3.7e-14 52.6 0.1 6.8e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 GAP87527.1 - 1.4e-09 38.2 0.0 3.5e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain PA14 PF07691.12 GAP87527.1 - 4e-06 26.7 0.0 1.5e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 PA14 domain Abhydrolase_1 PF00561.20 GAP87528.1 - 3.9e-19 69.3 0.1 7.7e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 GAP87528.1 - 4e-15 55.8 0.0 8e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DUF3176 PF11374.8 GAP87529.1 - 5.3e-32 110.2 2.2 1.2e-31 109.1 2.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Presenilin PF01080.17 GAP87529.1 - 0.062 12.0 0.3 0.098 11.4 0.3 1.3 1 0 0 1 1 1 0 Presenilin FAE1_CUT1_RppA PF08392.12 GAP87529.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein HemY_N PF07219.13 GAP87530.1 - 0.006 16.8 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 HemY protein N-terminus DUF5531 PF17671.1 GAP87530.1 - 0.25 11.2 0.7 0.53 10.2 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5531) EphA2_TM PF14575.6 GAP87530.1 - 0.56 11.1 1.6 11 7.0 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NEMP PF10225.9 GAP87530.1 - 1.6 8.4 4.0 7 6.2 0.1 2.7 2 1 1 3 3 3 0 NEMP family Spt20 PF12090.8 GAP87530.1 - 2.2 7.9 17.7 3.1 7.4 17.7 1.1 1 0 0 1 1 1 0 Spt20 family DUF1561 PF07598.11 GAP87531.1 - 0.022 13.0 0.1 0.032 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) UQ_con PF00179.26 GAP87532.1 - 4e-06 26.5 0.0 7.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme adh_short PF00106.25 GAP87533.1 - 7.9e-31 107.0 0.2 1.5e-23 83.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87533.1 - 5.7e-24 85.0 0.1 1.4e-21 77.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87533.1 - 0.00038 20.4 0.0 0.00064 19.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 GAP87533.1 - 0.13 12.0 0.2 2.7 7.8 0.2 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AA_kinase PF00696.28 GAP87534.1 - 2.1e-34 119.2 0.1 4.2e-34 118.2 0.0 1.6 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.6 GAP87534.1 - 9.4e-09 34.9 4.1 7.9e-07 28.8 2.2 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 GAP87534.1 - 3.1e-05 23.6 3.1 0.00048 19.8 1.0 2.8 2 0 0 2 2 2 1 ACT domain CN_hydrolase PF00795.22 GAP87535.1 - 5.3e-56 189.8 0.0 6.1e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cys_Met_Meta_PP PF01053.20 GAP87536.1 - 6e-141 469.4 0.0 6.9e-141 469.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAP87536.1 - 1.1e-08 34.5 0.2 4.7e-08 32.4 0.1 1.8 1 1 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAP87536.1 - 1.1e-07 31.3 0.0 1.6e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 GAP87536.1 - 3.1e-07 30.0 0.0 6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 GAP87536.1 - 0.0006 19.2 0.7 0.0059 15.9 0.4 2.5 2 1 0 2 2 2 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 GAP87536.1 - 0.0027 16.3 0.0 0.004 15.7 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 GAP87536.1 - 0.015 14.0 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDC-P PF02347.16 GAP87536.1 - 0.018 13.9 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein BRK PF07533.16 GAP87536.1 - 0.046 13.4 0.7 2.4 7.8 0.4 2.4 2 0 0 2 2 2 0 BRK domain ADH_zinc_N PF00107.26 GAP87536.1 - 0.052 13.5 0.1 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase CorA PF01544.18 GAP87538.1 - 2.2e-07 30.5 0.1 3.9e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PdxJ PF03740.13 GAP87538.1 - 0.069 12.3 0.2 0.11 11.5 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Pkinase PF00069.25 GAP87539.1 - 2.2e-73 246.9 0.0 2.7e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87539.1 - 1.1e-37 129.8 0.0 1.4e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP87539.1 - 2e-08 33.9 0.0 3.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Rad21_Rec8 PF04824.16 GAP87539.1 - 0.11 11.8 0.3 0.31 10.4 0.3 1.7 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Lectin_leg-like PF03388.13 GAP87540.1 - 6.5e-66 222.0 0.0 8.1e-66 221.6 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 GAP87540.1 - 0.001 18.7 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.10 GAP87540.1 - 0.13 12.0 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 LMBR1 PF04791.16 GAP87541.1 - 3.7e-117 392.4 3.1 4.2e-117 392.2 3.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein APH PF01636.23 GAP87543.1 - 3.1e-07 30.6 0.0 5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP87543.1 - 0.00018 21.2 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase p450 PF00067.22 GAP87544.1 - 1.2e-59 202.4 0.0 1.7e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 GAP87544.1 - 8e-23 80.7 2.9 1.3e-22 80.0 2.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP87544.1 - 1.5e-07 31.4 0.0 3.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Lactonase PF10282.9 GAP87545.1 - 4.3e-78 263.0 0.0 5.2e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller BAR PF03114.18 GAP87546.1 - 5.5e-65 219.4 4.0 7.1e-65 219.0 4.0 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 GAP87546.1 - 0.0013 19.4 0.2 0.01 16.5 0.0 2.5 2 1 1 3 3 3 1 CP12 domain HisKA_3 PF07730.13 GAP87546.1 - 3.5 8.2 6.0 5.4 7.6 0.5 2.8 3 0 0 3 3 3 0 Histidine kinase Pept_tRNA_hydro PF01195.19 GAP87547.1 - 1.7e-24 86.7 0.0 2e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Histone_HNS PF00816.21 GAP87548.1 - 1.1 10.1 6.0 0.32 11.9 1.2 2.6 2 1 1 3 3 3 0 H-NS histone family DUF4226 PF10774.9 GAP87548.1 - 2 8.7 9.1 6.4 7.1 5.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) DUF4279 PF14106.6 GAP87549.1 - 0.092 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) p450 PF00067.22 GAP87551.1 - 2.7e-57 194.6 0.0 4.5e-40 137.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Ribosomal_L13 PF00572.18 GAP87552.1 - 2.1e-12 47.4 0.0 1.9e-10 41.0 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.20 GAP87552.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain BAG PF02179.16 GAP87553.1 - 3.1e-17 62.8 0.8 5.5e-17 62.0 0.8 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 GAP87553.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Glutaredoxin PF00462.24 GAP87554.1 - 2.2e-19 69.4 0.0 3.9e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 GAP87554.1 - 0.0076 16.7 0.0 0.016 15.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 GAP87554.1 - 0.014 15.8 0.0 0.018 15.5 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 GAP87554.1 - 0.059 13.1 0.1 0.21 11.3 0.1 1.8 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Dak1 PF02733.17 GAP87554.1 - 0.074 11.9 0.1 0.086 11.7 0.1 1.1 1 0 0 1 1 1 0 Dak1 domain TraF PF13728.6 GAP87554.1 - 0.082 12.7 0.0 0.099 12.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Chalcone_2 PF16035.5 GAP87555.1 - 4.2e-78 261.8 0.0 5.3e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 GAP87555.1 - 0.016 15.3 0.0 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 Chalcone isomerase-like FAD_binding_3 PF01494.19 GAP87556.1 - 2.5e-18 66.4 3.7 1.4e-16 60.7 3.7 2.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAP87556.1 - 0.0022 18.2 0.1 0.0049 17.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 GAP87556.1 - 0.0053 15.9 0.0 0.0092 15.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 GAP87556.1 - 0.017 14.3 0.1 0.026 13.8 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP87556.1 - 0.018 13.8 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAP87556.1 - 0.057 12.7 0.1 0.091 12.0 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP87556.1 - 0.09 12.0 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 GAP87556.1 - 0.11 13.1 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAP87556.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Cyclin_C_2 PF16899.5 GAP87557.1 - 2.3e-33 114.7 0.1 2.2e-30 105.1 0.0 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 GAP87557.1 - 0.00014 21.6 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3176 PF11374.8 GAP87558.1 - 1.7e-30 105.4 0.8 1.7e-30 105.4 0.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF2721 PF11026.8 GAP87558.1 - 0.049 13.5 0.1 0.99 9.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Pkinase PF00069.25 GAP87559.1 - 2.7e-13 49.9 0.0 3.6e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAP87559.1 - 2.9e-07 30.7 0.1 4.2e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 GAP87559.1 - 1.7e-06 27.5 0.0 2.4e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP87559.1 - 1.2e-05 24.8 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAP87559.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 GAP87559.1 - 0.0071 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 GAP87559.1 - 0.073 12.6 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2249 PF10006.9 GAP87559.1 - 0.084 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Pkinase_fungal PF17667.1 GAP87559.1 - 0.2 10.4 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase AA_permease PF00324.21 GAP87560.1 - 1.1e-121 406.8 36.1 1.3e-121 406.6 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP87560.1 - 5.4e-32 111.2 39.7 6.3e-32 110.9 39.7 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 GAP87561.1 - 6.8e-18 64.7 0.0 8.9e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HARP PF07443.13 GAP87561.1 - 0.05 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 HepA-related protein (HARP) zf-C3HC4_5 PF17121.5 GAP87561.1 - 0.066 13.1 0.2 8.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.6 GAP87562.1 - 2.9e-12 46.7 0.2 5.7e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAP87562.1 - 4.8e-07 29.5 0.2 0.012 15.0 0.0 2.0 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 GAP87562.1 - 8.2e-07 29.5 1.8 1.1 9.8 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAP87562.1 - 2.3e-06 27.3 0.9 0.023 14.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAP87562.1 - 5.1e-06 26.2 0.3 0.21 11.5 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAP87562.1 - 8.2e-06 25.4 1.1 0.024 14.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 GAP87562.1 - 0.00042 20.7 0.0 1.6 9.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP87562.1 - 0.00049 20.3 0.1 2.7 8.3 0.0 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAP87562.1 - 0.0022 18.6 0.0 2.2 9.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAP87562.1 - 0.0039 17.3 1.0 0.6 10.5 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAP87562.1 - 0.0056 17.4 0.6 11 7.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAP87562.1 - 0.0064 16.4 0.3 0.64 10.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAP87562.1 - 0.016 15.6 0.2 13 6.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 GAP87562.1 - 0.13 11.9 0.1 7.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Response_reg PF00072.24 GAP87563.1 - 1e-15 57.9 0.0 2.3e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 GAP87563.1 - 9.8e-12 45.4 0.0 2.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 GAP87563.1 - 2.7e-08 33.7 0.1 1.2e-07 31.7 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Fer2 PF00111.27 GAP87564.1 - 5.4e-14 51.9 1.0 6.6e-14 51.6 1.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAA_hydrolase_N PF09298.11 GAP87564.1 - 0.03 14.5 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal MCR PF18509.1 GAP87564.1 - 0.21 11.2 1.9 0.38 10.4 1.9 1.5 1 0 0 1 1 1 0 Magnetochrome domain Rrp15p PF07890.12 GAP87565.1 - 2e-32 112.4 9.2 2e-32 112.4 9.2 2.2 2 1 0 2 2 2 1 Rrp15p TauD PF02668.16 GAP87566.1 - 1.1e-45 156.6 0.1 1.6e-45 156.0 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 GAP87566.1 - 1e-05 26.1 0.0 3e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 GAP87566.1 - 0.00012 21.3 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 CsiD IL17 PF06083.11 GAP87566.1 - 0.13 12.8 0.3 0.36 11.3 0.0 1.9 2 0 0 2 2 2 0 Interleukin-17 HEAT_EZ PF13513.6 GAP87568.1 - 4.5e-27 94.1 19.4 3.6e-14 52.9 0.1 11.5 11 2 3 14 14 13 3 HEAT-like repeat HEAT PF02985.22 GAP87568.1 - 1.7e-25 86.9 12.7 5.7e-05 23.0 0.0 10.2 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.6 GAP87568.1 - 3.3e-20 72.3 3.5 1.2e-05 25.6 0.2 7.1 5 2 2 7 7 6 4 HEAT repeats Cnd1 PF12717.7 GAP87568.1 - 9.1e-12 45.3 0.1 0.006 16.6 0.0 4.9 4 0 0 4 4 4 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 GAP87568.1 - 5.9e-11 42.8 0.0 0.18 12.4 0.0 6.1 4 3 3 7 7 7 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 GAP87568.1 - 1.5e-09 37.5 0.1 0.045 12.9 0.0 4.9 4 1 1 5 5 5 3 RNAPII transcription regulator C-terminal IBN_N PF03810.19 GAP87568.1 - 2e-06 27.6 1.8 6.5e-05 22.8 0.1 4.2 4 1 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.8 GAP87568.1 - 2.7e-06 27.1 0.4 17 4.9 0.0 7.1 6 3 1 7 7 7 0 CLASP N terminal Adaptin_N PF01602.20 GAP87568.1 - 4e-06 25.7 0.2 0.007 15.0 0.0 3.0 3 0 0 3 3 3 2 Adaptin N terminal region Mo25 PF08569.11 GAP87568.1 - 0.0029 17.0 0.2 0.32 10.3 0.0 2.7 3 0 0 3 3 3 1 Mo25-like Arm PF00514.23 GAP87568.1 - 0.0073 16.3 5.4 49 4.2 0.1 6.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 GAP87568.1 - 0.013 15.7 0.0 0.096 12.9 0.0 2.6 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 GAP87568.1 - 0.069 13.1 0.4 2.9 7.8 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) TAF6_C PF07571.13 GAP87568.1 - 0.083 13.2 0.0 7.5 6.9 0.0 3.9 5 2 1 6 6 6 0 TAF6 C-terminal HEAT repeat domain CTD_bind PF04818.13 GAP87569.1 - 3.2e-14 53.5 0.0 1.1e-13 51.8 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF4748 PF15932.5 GAP87570.1 - 2.5e-24 84.8 0.3 3.3e-24 84.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) ACTH_assoc PF16102.5 GAP87570.1 - 1.4 9.9 7.9 6.9 7.7 0.8 3.5 4 0 0 4 4 4 0 ACTH-associated domain Exo_endo_phos PF03372.23 GAP87571.1 - 2.4e-10 40.3 1.7 4.3e-10 39.5 0.2 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Questin_oxidase PF14027.6 GAP87573.1 - 6e-85 285.8 0.7 7.2e-85 285.5 0.7 1.1 1 0 0 1 1 1 1 Questin oxidase-like USP7_ICP0_bdg PF12436.8 GAP87574.1 - 2.5e-82 275.8 0.0 1.3e-80 270.2 0.0 2.4 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 GAP87574.1 - 1.3e-74 250.4 5.4 2.4e-72 242.9 2.5 2.9 2 1 1 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 GAP87574.1 - 1.3e-47 162.5 1.5 2.4e-47 161.6 1.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAP87574.1 - 1.8e-23 83.7 0.1 5.7e-23 82.0 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 GAP87574.1 - 1.2e-09 38.3 0.0 3.9e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 MATH domain YukD PF08817.10 GAP87574.1 - 0.025 15.3 0.0 18 6.1 0.0 3.0 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD Rrp40_N PF18311.1 GAP87574.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease Rrp40 N-terminal domain BCDHK_Adom3 PF10436.9 GAP87575.1 - 5.8e-45 153.0 0.0 9.1e-45 152.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAP87575.1 - 1.1e-05 25.9 0.0 5.3e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 GAP87575.1 - 0.053 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Septin PF00735.18 GAP87576.1 - 7e-115 383.1 0.3 1e-114 382.6 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAP87576.1 - 1.4e-07 31.6 0.0 3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP87576.1 - 6.8e-06 26.1 2.3 2e-05 24.5 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 GAP87576.1 - 1.1e-05 25.1 4.4 8.6e-05 22.2 0.2 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 GAP87576.1 - 0.0016 18.7 1.0 0.0051 17.1 0.1 2.2 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 GAP87576.1 - 0.0025 17.3 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 GAP87576.1 - 0.0028 17.9 0.2 0.0063 16.7 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 GAP87576.1 - 0.004 16.5 0.0 0.0086 15.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 GAP87576.1 - 0.0076 15.3 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 GAP87576.1 - 0.018 14.8 0.4 0.046 13.4 0.4 1.7 1 1 0 1 1 1 0 AAA domain Casc1_N PF15927.5 GAP87576.1 - 0.018 14.7 12.0 0.049 13.3 12.0 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus KAP_NTPase PF07693.14 GAP87576.1 - 0.025 13.8 0.0 0.037 13.3 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Ras PF00071.22 GAP87576.1 - 0.028 14.0 0.8 0.085 12.5 0.7 1.9 2 1 0 2 2 1 0 Ras family Val_tRNA-synt_C PF10458.9 GAP87576.1 - 0.032 14.5 2.5 0.093 13.0 0.4 2.7 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm T2SSE PF00437.20 GAP87576.1 - 0.04 13.0 0.4 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 GAP87576.1 - 0.049 14.1 0.4 0.16 12.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 GAP87576.1 - 0.05 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 GAP87576.1 - 0.051 14.0 2.0 0.09 13.2 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain FOXP-CC PF16159.5 GAP87576.1 - 0.066 13.9 1.3 0.066 13.9 1.3 2.7 3 1 1 4 4 2 0 FOXP coiled-coil domain Sigma54_activat PF00158.26 GAP87576.1 - 0.077 12.7 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 GAP87576.1 - 0.09 13.2 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.6 GAP87576.1 - 0.09 12.3 0.2 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ribosomal_L6e PF01159.19 GAP87576.1 - 1 9.9 7.5 2.7 8.5 0.3 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e Dynamin_N PF00350.23 GAP87576.1 - 1.2 9.1 8.7 4.5 7.3 0.1 3.2 2 1 1 3 3 3 0 Dynamin family APG6_N PF17675.1 GAP87576.1 - 2.7 8.5 15.7 0.51 10.9 10.3 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region FUSC PF04632.12 GAP87576.1 - 3.9 5.9 4.1 5.5 5.4 4.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Seryl_tRNA_N PF02403.22 GAP87576.1 - 5.2 7.3 10.2 5.2 7.4 5.6 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_11 PF13086.6 GAP87576.1 - 5.6 6.7 8.2 19 4.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 GAP87577.1 - 8.4e-41 137.2 26.9 1.4e-07 32.1 0.0 13.3 14 0 0 14 14 14 7 WD domain, G-beta repeat Utp12 PF04003.12 GAP87577.1 - 1.8e-24 86.1 0.0 2.7e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 GAP87577.1 - 7.8e-21 74.2 0.0 0.0057 16.9 0.0 10.0 3 2 7 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP87577.1 - 1.1e-08 34.5 1.8 3.6 6.5 0.0 6.1 3 1 2 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAP87577.1 - 4.3e-06 26.7 2.6 0.059 13.2 0.1 5.4 6 1 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAP87577.1 - 0.0013 18.1 0.0 1.4 8.1 0.0 3.8 4 0 0 4 4 4 1 WD40-like domain Nup160 PF11715.8 GAP87577.1 - 0.0015 17.3 2.2 4.2 5.9 0.1 4.0 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 GAP87577.1 - 0.022 14.1 0.1 10 5.4 0.0 3.4 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 GAP87577.1 - 0.12 12.3 2.2 13 5.8 0.1 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Vps39_2 PF10367.9 GAP87579.1 - 9.5e-08 32.5 0.0 2.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 GAP87579.1 - 0.0055 17.0 0.0 0.061 13.6 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.12 GAP87580.1 - 1.4e-96 322.7 19.4 1.3e-95 319.6 0.0 3.1 3 1 1 4 4 4 1 CASP C terminal PI3K_P85_iSH2 PF16454.5 GAP87580.1 - 0.0064 16.1 33.4 0.17 11.5 12.1 4.9 3 1 2 5 5 5 3 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ERM PF00769.19 GAP87580.1 - 0.008 16.0 2.3 0.008 16.0 2.3 4.3 4 1 1 5 5 5 2 Ezrin/radixin/moesin family HR1 PF02185.16 GAP87580.1 - 0.012 15.8 2.2 0.012 15.8 2.2 5.2 5 0 0 5 5 5 0 Hr1 repeat HAP1_N PF04849.13 GAP87580.1 - 0.03 13.5 0.1 0.03 13.5 0.1 4.6 2 1 2 4 4 2 0 HAP1 N-terminal conserved region ZapB PF06005.12 GAP87580.1 - 0.1 13.1 0.3 0.1 13.1 0.3 6.8 4 3 2 6 6 5 0 Cell division protein ZapB SlyX PF04102.12 GAP87580.1 - 0.14 12.8 0.0 0.14 12.8 0.0 6.9 7 0 0 7 7 7 0 SlyX NAD_binding_1 PF00175.21 GAP87580.1 - 0.39 11.4 2.5 5.1 7.8 0.0 3.6 3 1 1 4 4 4 0 Oxidoreductase NAD-binding domain TolA_bind_tri PF16331.5 GAP87580.1 - 0.73 10.0 41.4 0.81 9.8 0.4 5.8 5 1 1 6 6 6 0 TolA binding protein trimerisation ATG16 PF08614.11 GAP87580.1 - 1.7 8.8 64.7 0.18 12.0 0.6 6.2 3 2 3 6 6 6 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 GAP87580.1 - 2 7.8 47.5 4.9 6.5 0.1 4.6 4 1 1 5 5 5 0 Golgin subfamily A member 5 APG6_N PF17675.1 GAP87580.1 - 2.2 8.8 58.5 3.7 8.1 1.5 5.7 2 1 3 5 5 5 0 Apg6 coiled-coil region MscS_porin PF12795.7 GAP87580.1 - 6.3 6.3 51.5 0.17 11.4 2.6 4.8 4 1 0 4 4 4 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 GAP87580.1 - 7.4 5.8 38.8 4.6 6.5 0.1 4.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) DUF3455 PF11937.8 GAP87581.1 - 5.9e-45 153.5 0.0 7.8e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 GAP87581.1 - 0.038 14.1 2.0 0.29 11.3 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2990) MF_alpha_N PF05436.11 GAP87581.1 - 0.07 13.0 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus Peptidase_C12 PF01088.21 GAP87582.1 - 6.8e-67 225.3 0.0 8.7e-67 224.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 GAP87582.1 - 9.8e-10 38.2 0.1 1.8e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Xan_ur_permease PF00860.20 GAP87583.1 - 7.4e-23 80.9 30.9 1.4e-22 80.0 28.5 2.5 2 1 0 2 2 2 1 Permease family 1-cysPrx_C PF10417.9 GAP87583.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin MFS_MOT1 PF16983.5 GAP87583.1 - 1.3 9.4 21.6 0.03 14.7 4.4 3.2 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Methyltransf_23 PF13489.6 GAP87584.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PSD1 PF07587.11 GAP87584.1 - 0.82 9.1 4.0 0.52 9.8 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1553) Dicty_CAR PF05462.11 GAP87585.1 - 2e-14 53.4 6.0 2e-14 53.4 6.0 1.7 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 GAP87585.1 - 3.8e-11 42.8 3.6 4e-11 42.7 2.4 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 GAP87585.1 - 1.1e-06 28.2 1.4 1.4e-06 27.9 1.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 GAP87585.1 - 6.1e-06 26.2 8.1 1.1e-05 25.3 8.1 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 STE3 PF02076.15 GAP87585.1 - 0.00017 20.9 2.7 0.00017 20.9 2.7 1.8 2 1 0 2 2 2 1 Pheromone A receptor Frizzled PF01534.17 GAP87585.1 - 0.00021 20.4 8.0 0.016 14.2 5.2 2.4 2 1 0 2 2 2 1 Frizzled/Smoothened family membrane region 7TM_GPCR_Srsx PF10320.9 GAP87585.1 - 0.0026 17.2 0.9 0.0042 16.5 0.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Glyco_transf_8 PF01501.20 GAP87586.1 - 5.1e-21 75.4 0.6 1.6e-19 70.4 0.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 GAP87586.1 - 0.0074 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Prok-E2_E PF14462.6 GAP87586.1 - 0.48 10.2 1.9 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family E Cation_efflux PF01545.21 GAP87587.1 - 8.4e-18 64.8 7.1 1.1e-17 64.4 7.1 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAP87587.1 - 1.9e-10 40.7 0.1 4.6e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter MRP-S33 PF08293.11 GAP87587.1 - 0.017 15.3 0.1 0.032 14.5 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 TctB PF07331.11 GAP87587.1 - 0.38 11.0 4.7 0.32 11.3 2.0 2.0 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF1700 PF08006.11 GAP87587.1 - 1.4 8.4 4.6 13 5.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) Glyco_hydro_47 PF01532.20 GAP87588.1 - 3e-177 590.1 0.0 3.5e-177 589.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 zf-rbx1 PF12678.7 GAP87589.1 - 9.3e-10 38.7 2.9 1.6e-09 37.9 2.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAP87589.1 - 3.7e-09 36.8 4.3 7.6e-09 35.8 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 GAP87589.1 - 1.5e-05 24.9 2.0 2.9e-05 24.0 2.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAP87589.1 - 1.6e-05 24.7 2.0 2.7e-05 23.9 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP87589.1 - 3e-05 23.9 1.6 8.6e-05 22.4 1.7 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAP87589.1 - 0.00013 21.8 4.3 0.0015 18.4 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAP87589.1 - 0.00031 20.7 1.1 0.00064 19.7 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 GAP87589.1 - 0.00073 19.3 2.1 0.00073 19.3 2.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAP87589.1 - 0.0011 18.8 2.6 0.0034 17.2 2.7 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 GAP87589.1 - 0.0011 18.5 0.3 0.0023 17.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 GAP87589.1 - 0.073 12.8 1.9 0.61 9.9 1.9 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 GAP87589.1 - 0.26 11.5 0.9 0.51 10.5 0.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SnoaL_2 PF12680.7 GAP87590.1 - 0.045 14.4 0.0 0.056 14.1 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Suc_Fer-like PF06999.12 GAP87591.1 - 1.1e-40 139.7 0.0 1.7e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like HET PF06985.11 GAP87591.1 - 1.1e-21 77.7 0.0 2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4611 PF15387.6 GAP87591.1 - 4.3 7.6 8.9 5.7 7.2 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Suc_Fer-like PF06999.12 GAP87592.1 - 3.3e-06 27.1 0.0 3.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Glyco_hydro_76 PF03663.14 GAP87593.1 - 2.5e-109 366.2 0.3 3.1e-109 365.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 GAP87593.1 - 0.032 13.3 0.3 0.43 9.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Period_C PF12114.8 GAP87593.1 - 0.82 9.2 3.9 1.5 8.4 3.9 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region FH2 PF02181.23 GAP87594.1 - 2e-84 283.9 4.8 2e-84 283.9 4.8 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 GAP87594.1 - 4.8e-65 218.7 0.1 1.5e-64 217.1 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 GAP87594.1 - 2.9e-53 180.4 0.3 2.9e-53 180.4 0.3 2.8 2 1 1 3 3 3 1 Diaphanous FH3 Domain Qua1 PF16274.5 GAP87594.1 - 0.48 10.3 2.6 1.1 9.2 0.4 2.7 2 0 0 2 2 2 0 Qua1 domain GTA_holin_3TM PF11351.8 GAP87594.1 - 0.81 10.2 3.0 3.7 8.1 3.0 2.2 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Bap31_Bap29_C PF18035.1 GAP87594.1 - 1.9 8.6 5.9 3.1 7.9 1.9 3.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Pro-NT_NN PF07421.11 GAP87594.1 - 3.4 7.9 6.0 0.7 10.1 0.4 2.5 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor DUF4131 PF13567.6 GAP87595.1 - 0.019 14.6 0.7 0.028 14.1 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) zf-RING_2 PF13639.6 GAP87596.1 - 4e-08 33.4 7.4 4e-08 33.4 7.4 2.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 GAP87596.1 - 5.2e-06 26.2 1.5 5.2e-06 26.2 1.5 2.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 GAP87596.1 - 3.6e-05 23.7 2.4 0.00011 22.2 2.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 GAP87596.1 - 0.00013 22.2 9.7 0.00013 22.2 9.7 2.8 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 GAP87596.1 - 0.016 15.2 2.7 0.016 15.2 2.7 2.9 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 GAP87596.1 - 0.33 10.8 13.6 0.03 14.2 5.9 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAP87596.1 - 0.66 10.2 11.3 0.13 12.5 5.6 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 GAP87596.1 - 1.1 9.3 10.7 0.053 13.5 4.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 GAP87596.1 - 1.9 8.4 12.4 10 6.1 5.1 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 RecR PF02132.15 GAP87596.1 - 5.5 6.7 8.4 19 4.9 0.5 3.2 3 0 0 3 3 3 0 RecR protein Hus1 PF04005.12 GAP87597.1 - 2e-88 296.3 0.0 2.3e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein DUF2807 PF10988.8 GAP87597.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain adh_short PF00106.25 GAP87598.1 - 8.1e-24 84.2 0.0 4.7e-22 78.4 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87598.1 - 1.6e-11 44.2 0.2 2.4e-11 43.6 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87598.1 - 9.1e-11 42.0 0.1 1.3e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAP87598.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAP87598.1 - 0.016 14.6 0.1 0.019 14.4 0.1 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAP87598.1 - 0.031 14.4 0.1 0.048 13.7 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 GAP87598.1 - 0.13 11.3 0.2 0.3 10.1 0.1 1.6 1 1 1 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAP87598.1 - 0.14 11.3 0.0 6.2 5.9 0.0 2.1 1 1 0 2 2 2 0 Male sterility protein Herpes_pp85 PF04637.12 GAP87601.1 - 0.43 8.9 3.8 0.63 8.4 3.8 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Sec16_C PF12931.7 GAP87602.1 - 5.9e-107 357.8 0.1 8.2e-107 357.3 0.1 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 GAP87602.1 - 3.9e-31 108.1 0.2 1.9e-30 105.9 0.0 2.4 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Nup96 PF12110.8 GAP87602.1 - 0.15 11.1 1.4 0.19 10.8 0.1 1.8 2 0 0 2 2 2 0 Nuclear protein 96 R3H-assoc PF13902.6 GAP87602.1 - 0.69 10.3 7.1 0.064 13.6 0.5 2.4 2 0 0 2 2 2 0 R3H-associated N-terminal domain DAO PF01266.24 GAP87603.1 - 4.6e-27 95.5 5.4 3.1e-26 92.8 5.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAP87603.1 - 0.1 11.8 0.0 0.3 10.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Kin17_mid PF10357.9 GAP87604.1 - 6.2e-51 171.6 1.2 6.2e-51 171.6 1.2 2.0 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 GAP87604.1 - 0.00027 21.1 0.4 0.00051 20.3 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP87604.1 - 0.0046 17.3 0.6 0.009 16.4 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAP87604.1 - 0.029 14.7 3.5 0.032 14.6 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Ndc1_Nup PF09531.10 GAP87604.1 - 7.9 5.0 9.4 10 4.6 9.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AA_kinase PF00696.28 GAP87605.1 - 3.4e-39 134.9 0.5 7.8e-39 133.7 0.1 1.7 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 GAP87605.1 - 7e-15 54.5 0.8 9.7e-09 34.9 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 GAP87605.1 - 1.4e-13 50.4 4.2 3.6e-09 36.3 0.3 2.7 2 0 0 2 2 2 2 ACT domain FMN_red PF03358.15 GAP87605.1 - 0.011 15.5 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 NADPH-dependent FMN reductase RFX_DNA_binding PF02257.15 GAP87606.1 - 1.4e-27 96.1 0.0 2.9e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.19 GAP87607.1 - 4.5e-28 97.0 10.2 4.5e-28 97.0 10.2 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Bestrophin PF01062.21 GAP87607.1 - 0.064 12.6 2.2 0.094 12.1 2.2 1.4 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF4407 PF14362.6 GAP87607.1 - 0.58 9.4 1.8 1.2 8.4 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IF4E PF01652.18 GAP87608.1 - 7.3e-53 178.6 0.3 1.3e-52 177.8 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E CAF1A PF12253.8 GAP87609.1 - 2.8e-21 75.5 3.2 2.8e-21 75.5 3.2 2.3 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A Borrelia_P83 PF05262.11 GAP87609.1 - 3.4 6.0 27.3 5 5.5 27.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein E1-E2_ATPase PF00122.20 GAP87610.1 - 3.9e-38 130.8 16.9 9.3e-31 106.7 0.2 3.6 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAP87610.1 - 1.1e-25 90.4 2.1 1.1e-25 90.4 2.1 3.2 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAP87610.1 - 2.1e-21 77.2 0.0 8.3e-20 72.0 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAP87610.1 - 4.1e-14 52.0 0.2 4.1e-14 52.0 0.2 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAP87610.1 - 4.6e-11 42.6 0.0 2.5e-09 37.1 0.0 2.8 2 1 1 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAP87610.1 - 2.3e-05 24.3 0.2 0.0002 21.2 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_3 PF13727.6 GAP87610.1 - 2 8.4 6.8 0.58 10.1 2.0 2.4 2 0 0 2 2 2 0 CoA-binding domain Ribosomal_L34 PF00468.17 GAP87611.1 - 2.3e-10 40.2 11.6 4.6e-10 39.3 11.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L34 Glyco_hydro_3_C PF01915.22 GAP87612.1 - 6.6e-48 163.4 0.1 1.9e-47 161.8 0.0 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAP87612.1 - 4.4e-43 147.9 0.0 6.7e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAP87612.1 - 8.8e-18 64.2 0.0 1.8e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Lipase_3 PF01764.25 GAP87613.1 - 4.5e-34 117.3 0.0 7.1e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 GAP87613.1 - 0.00033 21.3 0.1 0.00041 21.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase3_N PF03893.16 GAP87613.1 - 0.0022 18.0 0.0 0.0067 16.4 0.0 1.9 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 GAP87613.1 - 0.05 12.9 0.1 0.088 12.1 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FMO-like PF00743.19 GAP87614.1 - 9.9e-24 83.6 0.0 4.3e-14 51.8 0.0 3.3 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAP87614.1 - 4.3e-11 42.6 0.0 1.5e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP87614.1 - 7.3e-10 39.0 4.7 1.3e-07 31.7 1.9 4.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 GAP87614.1 - 3.4e-09 36.3 1.3 5.7e-05 22.4 0.4 3.7 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAP87614.1 - 9.9e-07 28.3 3.2 0.00076 18.8 0.1 2.9 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP87614.1 - 1.3e-06 28.5 1.4 6.1e-06 26.4 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP87614.1 - 2.9e-05 23.8 1.1 0.007 16.0 0.2 3.1 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAP87614.1 - 6.3e-05 22.3 0.9 0.007 15.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 GAP87614.1 - 0.0091 16.5 0.1 2 9.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP87614.1 - 0.017 13.8 2.0 0.038 12.7 0.4 2.1 3 0 0 3 3 3 0 HI0933-like protein Amino_oxidase PF01593.24 GAP87614.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 GAP87614.1 - 0.031 14.3 0.0 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MCRA PF06100.11 GAP87614.1 - 0.047 12.5 0.3 0.076 11.8 0.3 1.2 1 0 0 1 1 1 0 MCRA family FAD_binding_3 PF01494.19 GAP87614.1 - 0.054 12.7 2.9 0.069 12.4 0.1 2.2 3 0 0 3 3 3 0 FAD binding domain FAD_binding_2 PF00890.24 GAP87614.1 - 0.096 11.7 0.4 0.52 9.3 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain LRR_4 PF12799.7 GAP87615.1 - 8e-06 26.1 0.7 0.18 12.3 0.5 4.7 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAP87615.1 - 0.0007 19.4 0.4 0.59 10.3 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_8 PF13855.6 GAP87615.1 - 0.0076 16.0 0.0 0.15 11.9 0.0 3.1 4 0 0 4 4 4 1 Leucine rich repeat SpoIIIAH PF12685.7 GAP87615.1 - 1.4 8.7 9.0 2.6 7.8 9.0 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein RR_TM4-6 PF06459.12 GAP87615.1 - 3.5 7.4 5.7 6.6 6.5 5.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM199X PF15814.5 GAP87615.1 - 9.3 5.2 10.0 15 4.5 10.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X SNF2_N PF00176.23 GAP87616.1 - 4.8e-45 153.8 1.9 6e-41 140.3 0.0 2.6 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP87616.1 - 3.5e-16 59.5 0.0 1.8e-15 57.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP87616.1 - 6.8e-06 26.2 0.3 2.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 GAP87616.1 - 3.7e-05 23.5 12.7 3.7e-05 23.5 12.7 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP87616.1 - 0.00039 20.2 11.1 0.00039 20.2 11.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP87616.1 - 0.00075 19.8 12.7 0.00075 19.8 12.7 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAP87616.1 - 0.0031 17.3 12.0 0.0031 17.3 12.0 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 GAP87616.1 - 0.023 13.9 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-Nse PF11789.8 GAP87616.1 - 0.54 10.1 5.0 2.2 8.2 5.0 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 GAP87616.1 - 0.59 10.0 11.8 1.7 8.6 11.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAP87616.1 - 1.4 9.3 9.3 4.2 7.7 9.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain AT_hook PF02178.19 GAP87616.1 - 1.7 8.8 8.9 0.13 12.2 2.0 2.8 2 0 0 2 2 2 0 AT hook motif Zn_Tnp_IS91 PF14319.6 GAP87616.1 - 8.1 6.6 9.7 1.5 8.9 2.2 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain tRNA-synt_1g PF09334.11 GAP87617.1 - 1.9e-98 329.8 0.1 5.5e-97 325.0 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAP87617.1 - 6.1e-22 77.6 4.3 1.1e-09 37.2 0.1 3.9 1 1 2 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 GAP87617.1 - 3.7e-10 39.7 0.1 0.00051 19.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 GAP87617.1 - 0.0045 17.0 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Acetyltransf_3 PF13302.7 GAP87618.1 - 4.4e-21 76.0 0.0 6.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP87618.1 - 2.5e-06 27.4 0.1 0.029 14.4 0.0 2.4 1 1 1 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.6 GAP87618.1 - 7.9e-06 25.6 0.2 0.4 10.4 0.0 3.2 2 1 1 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAP87618.1 - 0.0014 18.6 0.1 0.055 13.4 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAP87618.1 - 0.0051 17.0 0.2 0.011 15.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP87618.1 - 0.0086 16.3 0.3 2.1 8.6 0.1 2.4 1 1 1 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP87618.1 - 0.06 13.8 0.2 0.16 12.4 0.2 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PALP PF00291.25 GAP87620.1 - 1.4e-56 192.1 1.0 1.7e-51 175.4 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme CheR_N PF03705.15 GAP87621.1 - 0.15 11.8 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain Antistasin PF02822.14 GAP87622.1 - 0.81 10.4 9.1 2.7 8.7 1.7 2.8 2 0 0 2 2 2 0 Antistasin family ABC_tran PF00005.27 GAP87623.1 - 1.9e-15 57.6 0.1 2e-14 54.3 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 GAP87623.1 - 4e-12 46.6 0.2 8.3e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAP87623.1 - 0.001 18.5 0.0 0.72 9.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF3584 PF12128.8 GAP87623.1 - 0.0014 16.2 0.2 0.0019 15.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 GAP87623.1 - 0.0022 17.7 0.1 0.0044 16.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 GAP87623.1 - 0.0061 17.1 0.1 0.0087 16.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 GAP87623.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 GAP87623.1 - 0.016 15.4 0.1 0.033 14.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAP87623.1 - 0.016 15.6 0.0 0.049 14.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 GAP87623.1 - 0.023 14.4 0.1 0.033 13.9 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 GAP87623.1 - 0.029 13.8 0.2 0.081 12.4 0.2 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_25 PF13481.6 GAP87623.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAP87623.1 - 0.038 14.4 0.9 0.088 13.2 0.9 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 GAP87623.1 - 0.041 14.2 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 GAP87623.1 - 0.043 13.7 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 GAP87623.1 - 0.046 13.3 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 GAP87623.1 - 0.096 12.7 0.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 GAP87623.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 GAP87623.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 GAP87623.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 GAP87623.1 - 0.18 11.7 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain CENP-I PF07778.11 GAP87624.1 - 1.3e-33 116.5 0.0 1.3e-32 113.2 0.0 2.1 1 1 0 1 1 1 1 Mis6 Acetyltransf_1 PF00583.25 GAP87625.1 - 2.9e-08 34.0 0.0 5.2e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP87625.1 - 3.8e-05 23.6 0.0 0.00052 20.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP87625.1 - 0.00048 20.5 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Nuc_deoxyrib_tr PF05014.15 GAP87625.1 - 0.14 12.2 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase DUF3384 PF11864.8 GAP87627.1 - 6.5e-116 388.1 1.0 1.2e-115 387.2 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 GAP87627.1 - 7.1e-53 178.9 0.0 1.5e-52 177.8 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 GAP87627.1 - 3.5e-36 125.0 0.0 1.4e-32 113.2 0.0 2.9 3 0 0 3 3 3 2 Tuberin DUF3361 PF11841.8 GAP87627.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Phosphoesterase PF04185.14 GAP87627.1 - 0.17 11.0 0.0 0.46 9.6 0.0 1.6 2 0 0 2 2 2 0 Phosphoesterase family CAS_CSE1 PF03378.15 GAP87628.1 - 1.8e-168 560.6 0.0 3.2e-168 559.8 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 GAP87628.1 - 7.9e-155 515.2 1.1 1.3e-154 514.5 1.1 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 GAP87628.1 - 7.8e-13 48.1 0.0 1.8e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF1071 PF06378.11 GAP87628.1 - 0.02 14.5 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Xpo1 PF08389.12 GAP87628.1 - 0.037 14.1 3.1 0.85 9.7 0.1 4.0 4 1 0 4 4 4 0 Exportin 1-like protein V-ATPase_H_N PF03224.14 GAP87628.1 - 0.13 11.6 0.2 0.57 9.4 0.1 2.2 2 0 0 2 2 2 0 V-ATPase subunit H Es2 PF09751.9 GAP87629.1 - 5e-111 372.5 2.6 2.2e-110 370.4 0.2 2.2 2 1 0 2 2 2 1 Nuclear protein Es2 DUF3246 PF11596.8 GAP87629.1 - 0.15 11.5 3.7 0.26 10.7 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) FMN_red PF03358.15 GAP87630.1 - 6e-21 74.8 0.1 8.7e-21 74.3 0.1 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAP87630.1 - 0.00051 19.8 0.0 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold CP_ATPgrasp_2 PF14403.6 GAP87630.1 - 0.097 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 EF-hand_1 PF00036.32 GAP87631.1 - 3.2e-25 85.8 14.0 7.2e-07 28.3 1.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAP87631.1 - 5e-24 84.5 14.5 1.1e-13 51.4 1.9 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GAP87631.1 - 2.3e-19 67.6 7.7 5.3e-05 22.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAP87631.1 - 9.7e-17 59.6 12.7 2.5e-06 26.7 0.7 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAP87631.1 - 8.1e-13 48.0 11.5 5.8e-05 22.8 0.8 4.1 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAP87631.1 - 6.6e-07 29.6 0.2 0.0053 17.1 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAP87631.1 - 1.7e-05 24.7 8.0 0.018 15.0 0.7 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 GAP87631.1 - 0.034 14.5 0.2 1 9.7 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 GAP87631.1 - 0.064 13.5 1.6 0.41 10.9 1.5 2.4 1 1 0 1 1 1 0 Dockerin type I domain EPL1 PF10513.9 GAP87632.1 - 1.2e-19 71.2 2.7 1.2e-19 71.2 2.7 2.4 2 1 0 2 2 2 1 Enhancer of polycomb-like Polbeta PF18765.1 GAP87632.1 - 0.03 14.4 0.1 0.072 13.2 0.1 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase PNK3P PF08645.11 GAP87632.1 - 0.037 13.7 0.2 0.071 12.8 0.2 1.4 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Peptidase_M22 PF00814.25 GAP87633.1 - 2.2e-79 267.0 0.1 2.6e-79 266.7 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family AMPKBI PF04739.15 GAP87634.1 - 2.7e-24 85.2 2.7 2.7e-24 85.2 2.7 2.5 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 GAP87634.1 - 5.1e-23 81.1 0.0 8.7e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Pkinase PF00069.25 GAP87636.1 - 5.7e-61 206.2 0.0 6.7e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87636.1 - 2.5e-27 95.8 0.0 3.4e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP87636.1 - 0.011 14.6 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 GAP87636.1 - 0.015 14.6 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 GAP87636.1 - 0.033 13.1 0.0 0.049 12.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain UCH PF00443.29 GAP87637.1 - 5e-24 85.2 0.0 7e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 GAP87637.1 - 2.7e-11 43.6 0.1 5.9e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 GAP87637.1 - 0.0025 17.4 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase EF1G PF00647.19 GAP87638.1 - 2.5e-40 136.9 0.1 4.4e-40 136.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 GAP87638.1 - 1.6e-13 50.7 0.0 5.1e-13 49.1 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAP87638.1 - 1.7e-10 41.1 0.0 5.4e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP87638.1 - 1.3e-08 34.7 0.1 8.9e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAP87638.1 - 5.1e-06 26.8 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAP87638.1 - 4.1e-05 23.7 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAP87638.1 - 0.037 14.3 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Chorion_3 PF05387.11 GAP87638.1 - 1.2 8.7 5.0 1.8 8.1 5.0 1.2 1 0 0 1 1 1 0 Chorion family 3 Ribosomal_S9 PF00380.19 GAP87639.1 - 1.8e-40 138.2 0.1 3.1e-40 137.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TFIIA PF03153.13 GAP87640.1 - 1 9.3 8.9 1.1 9.1 8.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2235 PF09994.9 GAP87641.1 - 5.6e-45 153.9 0.0 1e-44 153.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.23 GAP87641.1 - 2.3e-07 30.9 0.0 5.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP87641.1 - 0.00017 21.5 0.1 0.0004 20.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 GAP87641.1 - 0.0043 16.4 0.1 0.014 14.6 0.0 1.8 2 0 0 2 2 2 1 Septin AAA_16 PF13191.6 GAP87641.1 - 0.011 16.2 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 GAP87641.1 - 0.034 13.3 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 GAP87641.1 - 0.041 13.8 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 GAP87641.1 - 0.046 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain HycH PF07450.11 GAP87641.1 - 0.074 13.4 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH AAA_23 PF13476.6 GAP87641.1 - 0.11 13.0 0.1 0.36 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 GAP87641.1 - 0.12 12.6 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 GAP87641.1 - 0.18 12.3 0.0 0.99 9.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter DUF2524 PF10732.9 GAP87641.1 - 0.27 11.6 0.8 0.52 10.6 0.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2524) Serglycin PF04360.12 GAP87642.1 - 0.025 14.5 4.5 0.025 14.5 4.5 3.3 2 1 1 3 3 3 0 Serglycin Glyco_hydro_61 PF03443.14 GAP87642.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 FAT PF02259.23 GAP87643.1 - 6.4e-72 242.6 6.3 6.4e-72 242.6 6.3 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 GAP87643.1 - 1.5e-29 103.6 0.0 4.1e-29 102.1 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 GAP87643.1 - 7.3e-08 32.1 0.2 1.8e-07 30.8 0.2 1.8 1 0 0 1 1 1 1 FATC domain FANCI_S2 PF14676.6 GAP87643.1 - 0.0027 18.1 1.2 4.3 7.6 0.0 4.3 4 0 0 4 4 4 2 FANCI solenoid 2 TPR_2 PF07719.17 GAP87643.1 - 2.1 8.6 6.4 10 6.5 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_1 PF00133.22 GAP87644.1 - 1.4e-217 723.7 0.0 1.5e-216 720.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAP87644.1 - 4.4e-31 107.9 0.0 1e-30 106.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAP87644.1 - 7.9e-14 51.2 1.1 0.0013 17.5 0.0 4.6 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 GAP87644.1 - 1.3e-09 37.9 0.0 4.3e-07 29.6 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 GAP87644.1 - 0.016 14.6 0.1 0.043 13.2 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain NAD_binding_2 PF03446.15 GAP87645.1 - 1.7e-32 112.8 0.0 2.4e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAP87645.1 - 9e-13 48.5 0.1 1.7e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAP87645.1 - 8.5e-06 26.3 0.0 1.6e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_1 PF00561.20 GAP87646.1 - 9.3e-22 77.9 0.1 1.1e-16 61.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP87646.1 - 2.3e-14 54.5 0.5 2.3e-14 54.5 0.5 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP87646.1 - 6.8e-09 35.3 0.1 1.3e-08 34.4 0.2 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAP87646.1 - 9.7e-06 25.5 0.2 0.019 14.7 0.0 2.1 1 1 1 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 GAP87646.1 - 0.00033 20.8 0.0 0.00047 20.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 GAP87646.1 - 0.06 13.0 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Chlorophyllase PF07224.11 GAP87646.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 GAP87646.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Palm_thioest PF02089.15 GAP87646.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ras PF00071.22 GAP87647.1 - 1.1e-12 47.9 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Ribosomal_S3Ae PF01015.18 GAP87648.1 - 2.4e-89 298.2 1.3 3e-89 298.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 GAP87648.1 - 0.024 15.2 0.1 0.33 11.5 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 GAP87648.1 - 0.035 14.1 0.6 0.27 11.3 0.0 2.4 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Ribosomal_L22 PF00237.19 GAP87648.1 - 0.06 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e Mitoc_mL59 PF18126.1 GAP87649.1 - 0.00081 19.7 0.1 0.00088 19.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 GTP_CH_N PF12471.8 GAP87650.1 - 1.6e-89 298.8 0.0 2.2e-89 298.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 GAP87650.1 - 1.4e-16 60.5 0.0 2.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF1996 PF09362.10 GAP87651.1 - 1.2e-73 247.9 2.5 1.5e-73 247.6 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Elf1 PF05129.13 GAP87652.1 - 7.8e-29 99.5 0.6 9.7e-29 99.2 0.6 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 GAP87652.1 - 0.25 11.5 1.8 0.71 10.0 1.8 1.8 1 1 1 2 2 2 0 Zinc ribbon domain UPRTase PF14681.6 GAP87653.1 - 1e-75 253.8 0.0 1.4e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAP87653.1 - 0.0012 18.4 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain WAPL PF07814.13 GAP87655.1 - 5.8e-53 180.0 0.0 1.1e-52 179.0 0.0 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.22 GAP87656.1 - 6.3e-45 152.7 0.1 7.2e-45 152.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP87656.1 - 6.7e-16 58.6 0.0 9.7e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP87656.1 - 1.1e-06 28.2 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAP87656.1 - 8.4e-06 25.5 0.0 4.2e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAP87656.1 - 9e-05 22.5 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAP87656.1 - 0.00056 19.4 0.0 0.0015 18.0 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAP87656.1 - 0.0011 18.9 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 GAP87656.1 - 0.0054 16.3 0.0 0.52 9.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_14 PF13173.6 GAP87656.1 - 0.018 15.0 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 GAP87656.1 - 0.18 11.2 0.0 0.5 9.8 0.0 1.8 2 1 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 GAP87656.1 - 0.19 12.1 0.0 0.42 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_C78 PF07910.13 GAP87657.1 - 4.3e-62 209.3 0.0 7.4e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 Ham1p_like PF01725.16 GAP87658.1 - 1.1e-55 188.5 0.0 1.2e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 GAP87659.1 - 1.5e-28 100.0 0.5 2.4e-28 99.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GAP87659.1 - 1.4e-07 32.0 0.1 2.2e-06 28.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 GAP87659.1 - 2.4e-06 28.0 0.1 0.00017 22.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 GAP87659.1 - 5.6e-06 26.7 1.4 8.4e-06 26.1 1.4 1.8 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 GAP87659.1 - 1.2e-05 25.5 0.1 0.0021 18.2 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.6 GAP87659.1 - 3.9e-05 23.8 0.3 0.0014 18.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 GAP87659.1 - 0.0007 19.3 0.3 0.28 10.8 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.6 GAP87659.1 - 0.0011 19.2 0.2 0.0027 18.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 GAP87659.1 - 0.0013 18.8 0.1 0.0038 17.4 0.1 1.7 1 1 0 1 1 1 1 Shikimate kinase Cytidylate_kin2 PF13189.6 GAP87659.1 - 0.0013 18.9 0.0 0.005 17.0 0.0 1.9 1 1 0 1 1 1 1 Cytidylate kinase-like family Hydin_ADK PF17213.3 GAP87659.1 - 0.0037 17.6 0.0 0.0062 16.8 0.0 1.3 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_30 PF13604.6 GAP87659.1 - 0.004 16.9 2.3 0.12 12.1 0.7 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 GAP87659.1 - 0.0055 17.1 0.1 0.0077 16.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 GAP87659.1 - 0.0063 16.4 0.2 0.014 15.3 0.2 1.6 1 0 0 1 1 1 1 NTPase dNK PF01712.19 GAP87659.1 - 0.01 15.7 1.8 0.89 9.4 0.1 2.2 1 1 0 2 2 2 1 Deoxynucleoside kinase KTI12 PF08433.10 GAP87659.1 - 0.011 15.2 0.0 0.027 13.9 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 GAP87659.1 - 0.015 15.6 0.4 0.033 14.5 0.2 1.7 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 GAP87659.1 - 0.019 14.7 0.5 0.035 13.9 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 GAP87659.1 - 0.034 13.9 1.6 0.085 12.6 0.2 2.3 2 2 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAP87659.1 - 0.036 13.8 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 GAP87659.1 - 0.04 13.7 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 GAP87659.1 - 0.055 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 GAP87659.1 - 0.057 12.5 0.1 0.099 11.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 GAP87659.1 - 0.065 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 GAP87659.1 - 0.098 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 GAP87659.1 - 0.11 12.1 0.5 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRP54 PF00448.22 GAP87659.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Arnt_C PF18583.1 GAP87659.1 - 0.11 12.1 0.9 9.9 5.8 0.1 2.6 3 0 0 3 3 3 0 Aminoarabinose transferase C-terminal domain MeaB PF03308.16 GAP87659.1 - 0.13 11.2 0.1 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Myosin_head PF00063.21 GAP87660.1 - 2.1e-257 855.8 0.0 3.8e-257 854.9 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 GAP87660.1 - 2.6e-26 91.9 2.7 2.6e-26 91.9 2.7 2.7 2 1 0 2 2 2 1 DIL domain IQ PF00612.27 GAP87660.1 - 9e-09 34.4 34.4 0.00017 21.1 0.7 7.1 7 0 0 7 7 6 3 IQ calmodulin-binding motif Myosin_N PF02736.19 GAP87660.1 - 0.0011 18.8 1.5 0.0011 18.8 1.5 2.2 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain GAS PF13851.6 GAP87660.1 - 0.0035 16.7 18.4 0.0035 16.7 18.4 2.6 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 GAP87660.1 - 0.0068 15.4 24.6 0.012 14.6 24.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AAA_22 PF13401.6 GAP87660.1 - 0.011 16.0 0.9 0.038 14.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 GAP87660.1 - 0.019 13.6 18.2 0.042 12.5 18.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAP87660.1 - 0.022 15.2 0.0 0.022 15.2 0.0 2.9 3 0 0 3 3 2 0 AAA ATPase domain DUF4164 PF13747.6 GAP87660.1 - 0.023 15.0 11.5 0.086 13.1 9.9 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Spc7 PF08317.11 GAP87660.1 - 0.029 13.3 21.9 0.073 11.9 21.9 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1336 PF07059.12 GAP87660.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) Fez1 PF06818.15 GAP87660.1 - 0.12 12.8 25.3 1.6 9.1 11.6 2.9 1 1 1 2 2 2 0 Fez1 Sec34 PF04136.15 GAP87660.1 - 0.16 11.8 14.1 0.075 12.9 6.1 2.7 1 1 1 2 2 2 0 Sec34-like family Phage_GP20 PF06810.11 GAP87660.1 - 0.38 10.5 19.6 0.24 11.2 7.7 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.12 GAP87660.1 - 1.3 9.1 16.0 5.8 7.0 12.5 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 GAP87660.1 - 1.7 9.1 19.6 3.2 8.3 6.1 3.6 2 1 0 2 2 2 0 Snapin/Pallidin KASH_CCD PF14662.6 GAP87660.1 - 2.5 7.9 32.5 0.47 10.2 10.2 3.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Seryl_tRNA_N PF02403.22 GAP87660.1 - 2.5 8.4 22.6 1.1 9.6 13.6 3.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Dna2 PF08696.11 GAP87660.1 - 2.8 7.7 9.3 1.2 8.9 5.6 2.3 1 1 1 2 2 2 0 DNA replication factor Dna2 DegQ PF08181.11 GAP87660.1 - 4.4 7.5 9.8 0.62 10.2 1.8 3.6 3 0 0 3 3 3 0 DegQ (SacQ) family UPF0242 PF06785.11 GAP87660.1 - 8.4 6.4 29.4 2.2 8.3 18.8 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 GAP87660.1 - 9.1 6.5 31.4 0.48 10.6 9.5 3.1 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 2-Hacid_dh_C PF02826.19 GAP87661.1 - 9.7e-53 178.2 0.0 1.5e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP87661.1 - 1.2e-35 122.0 0.0 1.8e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 GAP87661.1 - 0.00014 21.6 0.3 0.00041 20.0 0.0 2.1 2 0 0 2 2 2 1 ACT domain NAD_binding_2 PF03446.15 GAP87661.1 - 0.0002 21.5 0.4 0.0005 20.3 0.2 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 GAP87661.1 - 0.011 16.2 0.0 0.035 14.6 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain IlvN PF07991.12 GAP87661.1 - 0.013 15.0 0.1 0.06 12.9 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 GAP87661.1 - 0.027 14.5 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Rossmann-like PF10727.9 GAP87661.1 - 0.06 13.2 0.5 0.15 11.9 0.5 1.6 1 0 0 1 1 1 0 Rossmann-like domain NCOA_u2 PF16665.5 GAP87661.1 - 0.16 12.3 0.3 0.28 11.5 0.3 1.4 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein NAP PF00956.18 GAP87662.1 - 7.5e-100 333.6 9.9 1.2e-99 332.9 9.9 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) YqgF PF14639.6 GAP87662.1 - 0.013 15.3 0.8 0.044 13.6 0.5 2.0 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 Striatin PF08232.12 GAP87662.1 - 0.019 15.5 1.9 0.019 15.5 1.9 2.2 2 1 0 2 2 2 0 Striatin family RNA_pol_3_Rpc31 PF11705.8 GAP87662.1 - 7.2 6.8 29.7 0.99 9.6 15.6 2.5 2 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 P5-ATPase PF12409.8 GAP87663.1 - 9.1e-42 142.1 0.3 5.5e-40 136.4 0.1 2.8 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 GAP87663.1 - 6.1e-29 100.8 0.7 1.6e-28 99.5 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAP87663.1 - 1.2e-14 55.1 0.0 4.3e-06 27.2 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAP87663.1 - 0.0087 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAP87663.1 - 0.028 14.5 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) CBP_BcsF PF11120.8 GAP87663.1 - 6.5 6.9 7.7 2.3 8.4 2.8 2.6 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF WD40 PF00400.32 GAP87664.1 - 1.9e-21 75.9 7.1 2.9e-07 31.1 0.3 5.6 4 1 1 5 5 5 4 WD domain, G-beta repeat Proteasome PF00227.26 GAP87665.1 - 7.5e-30 103.8 0.0 8.3e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.29 GAP87666.1 - 5.9e-49 166.2 0.0 2.1e-48 164.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP87666.1 - 1.2e-32 112.6 0.0 3e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP87666.1 - 0.0048 16.9 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAP87666.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 GAP87666.1 - 0.22 10.7 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ABC_membrane PF00664.23 GAP87668.1 - 2.9e-55 187.9 33.4 4.6e-35 121.6 18.8 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 GAP87668.1 - 5.2e-47 159.8 0.0 1.2e-27 97.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.12 GAP87668.1 - 9.1e-06 25.1 0.0 0.00051 19.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 GAP87668.1 - 1.7e-05 25.2 0.1 0.071 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 GAP87668.1 - 2.6e-05 24.3 1.8 0.031 14.4 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 GAP87668.1 - 0.00031 20.7 0.3 0.98 9.2 0.2 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAP87668.1 - 0.0006 19.3 0.7 4.5 6.7 0.0 3.4 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAP87668.1 - 0.0014 18.9 0.8 2.2 8.5 0.1 2.9 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAP87668.1 - 0.0016 18.4 4.2 0.16 11.9 0.1 2.6 3 0 0 3 3 2 2 RsgA GTPase AAA_29 PF13555.6 GAP87668.1 - 0.0029 17.3 2.0 2.1 8.1 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 GAP87668.1 - 0.004 17.3 2.1 0.18 11.9 0.4 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 GAP87668.1 - 0.0052 16.5 1.8 0.89 9.2 0.3 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 GAP87668.1 - 0.0099 16.4 2.7 4.1 7.9 0.1 2.8 3 0 0 3 3 2 2 AAA domain Roc PF08477.13 GAP87668.1 - 0.014 15.7 0.1 4.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 GAP87668.1 - 0.02 14.5 0.5 0.48 10.0 0.1 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 GAP87668.1 - 0.028 13.3 0.8 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 GAP87668.1 - 0.041 13.0 0.1 0.66 9.0 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein MeaB PF03308.16 GAP87668.1 - 0.051 12.5 0.7 3.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 GAP87668.1 - 0.057 13.1 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 GAP87668.1 - 0.06 12.9 0.6 2.9 7.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 GAP87668.1 - 0.06 13.4 4.5 0.41 10.7 0.4 2.6 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.6 GAP87668.1 - 0.063 13.5 0.8 0.33 11.2 0.0 2.5 3 0 0 3 3 2 0 AAA domain Orf78 PF06024.12 GAP87668.1 - 0.067 13.5 0.9 3.8 7.9 0.8 2.9 2 0 0 2 2 2 0 Orf78 (ac78) Ploopntkinase3 PF18751.1 GAP87668.1 - 0.072 13.0 0.3 14 5.5 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 GAP87668.1 - 0.089 12.7 0.3 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 GAP87668.1 - 0.15 12.1 0.2 5.9 6.9 0.0 2.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 GAP87668.1 - 0.24 11.0 2.0 0.77 9.3 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 GAP87668.1 - 0.5 10.1 2.4 8.1 6.1 0.2 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Apt1 PF10351.9 GAP87669.1 - 0.00066 18.6 4.2 0.00091 18.2 4.2 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain GREB1 PF15782.5 GAP87669.1 - 4.1 4.4 6.6 5.2 4.1 6.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fcf1 PF04900.12 GAP87670.1 - 1.9e-36 124.4 0.6 4.5e-36 123.2 0.4 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 GAP87670.1 - 3.7e-11 43.3 0.1 1.1e-10 41.8 0.0 1.7 2 0 0 2 2 2 1 PIN like domain Dehyd-heme_bind PF09098.10 GAP87670.1 - 0.045 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding RNase_T PF00929.24 GAP87671.1 - 2.2e-07 31.6 0.0 3.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 GAP87671.1 - 0.00023 20.9 0.0 0.00062 19.5 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease zf-C2H2_jaz PF12171.8 GAP87671.1 - 0.013 15.8 0.2 0.032 14.5 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP87671.1 - 0.1 13.0 0.1 0.1 13.0 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type N-SET PF11764.8 GAP87672.1 - 5e-50 170.0 2.6 5e-50 170.0 2.6 2.6 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 GAP87672.1 - 4.2e-25 87.2 0.2 2.6e-24 84.7 0.0 2.4 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated SET PF00856.28 GAP87672.1 - 7.7e-20 72.0 0.2 7.7e-20 72.0 0.2 4.0 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.22 GAP87672.1 - 0.014 15.2 0.5 0.18 11.6 0.5 2.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Usp PF00582.26 GAP87673.1 - 0.96 10.0 3.5 3.7 8.1 0.2 2.5 2 0 0 2 2 2 0 Universal stress protein family DNA_pol_phi PF04931.13 GAP87673.1 - 6.4 4.7 7.4 30 2.5 6.1 2.0 2 0 0 2 2 2 0 DNA polymerase phi Tropomyosin_1 PF12718.7 GAP87674.1 - 1.1e-49 168.3 34.1 1.3e-49 168.0 34.1 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 GAP87674.1 - 1.2e-06 28.1 32.9 0.00057 19.3 6.8 3.0 1 1 2 3 3 3 3 Tropomyosin DUF4200 PF13863.6 GAP87674.1 - 8.4e-05 23.0 32.9 0.0064 16.9 14.1 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 GAP87674.1 - 0.00013 22.1 35.1 0.0012 18.9 6.2 2.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 GAP87674.1 - 0.00048 20.2 6.8 0.00048 20.2 6.8 2.1 1 1 1 2 2 2 1 Laminin Domain II DUF3450 PF11932.8 GAP87674.1 - 0.00083 18.7 27.7 0.045 13.1 10.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 GAP87674.1 - 0.0014 18.7 32.0 0.044 13.9 3.2 5.1 1 1 4 5 5 5 2 bZIP transcription factor DUF724 PF05266.14 GAP87674.1 - 0.0022 17.9 28.3 0.015 15.1 9.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF724) BRE1 PF08647.11 GAP87674.1 - 0.0024 17.9 28.6 0.34 11.0 16.7 2.7 1 1 1 2 2 2 2 BRE1 E3 ubiquitin ligase CENP-K PF11802.8 GAP87674.1 - 0.003 17.2 20.4 0.27 10.8 5.7 2.1 1 1 1 2 2 2 2 Centromere-associated protein K Uso1_p115_C PF04871.13 GAP87674.1 - 0.0046 17.3 34.8 0.022 15.1 13.4 2.0 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 GAP87674.1 - 0.009 15.4 32.1 0.18 11.1 24.3 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding ERM PF00769.19 GAP87674.1 - 0.01 15.7 38.2 0.021 14.6 17.1 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HrpB7 PF09486.10 GAP87674.1 - 0.013 15.8 19.6 0.013 15.9 17.8 1.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) FlaC_arch PF05377.11 GAP87674.1 - 0.015 15.7 20.1 0.95 9.9 3.3 4.2 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) KASH_CCD PF14662.6 GAP87674.1 - 0.017 15.0 33.1 0.5 10.2 12.7 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH TACC_C PF05010.14 GAP87674.1 - 0.023 14.5 24.1 0.022 14.5 14.1 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spc7 PF08317.11 GAP87674.1 - 0.034 13.0 33.9 0.035 13.0 20.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 GAP87674.1 - 0.044 14.0 34.7 0.84 9.8 15.9 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 GAP87674.1 - 0.052 13.2 34.9 1.6 8.4 21.8 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Taxilin PF09728.9 GAP87674.1 - 0.068 12.3 29.8 0.54 9.4 17.8 2.2 1 1 1 2 2 2 0 Myosin-like coiled-coil protein ADIP PF11559.8 GAP87674.1 - 0.096 12.8 33.5 0.7 10.0 10.4 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding KLRAQ PF10205.9 GAP87674.1 - 0.1 12.8 23.5 0.31 11.3 7.6 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein TMF_TATA_bd PF12325.8 GAP87674.1 - 0.14 12.4 28.3 3.4 7.9 18.9 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HMMR_N PF15905.5 GAP87674.1 - 0.14 11.6 31.5 0.26 10.7 31.5 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 GAP87674.1 - 0.15 12.6 40.1 0.089 13.3 24.7 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 GAP87674.1 - 0.16 12.0 14.6 0.17 11.9 5.5 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) HOOK PF05622.12 GAP87674.1 - 0.17 10.0 26.7 0.24 9.5 26.7 1.1 1 0 0 1 1 1 0 HOOK protein ZapB PF06005.12 GAP87674.1 - 0.2 12.1 40.3 1.4 9.4 1.8 4.3 1 1 2 3 3 2 0 Cell division protein ZapB Fez1 PF06818.15 GAP87674.1 - 0.22 12.0 28.2 0.59 10.6 28.4 1.6 1 1 0 1 1 1 0 Fez1 CALCOCO1 PF07888.11 GAP87674.1 - 0.24 10.2 32.7 0.22 10.4 8.5 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like UPF0242 PF06785.11 GAP87674.1 - 0.3 11.2 33.2 0.13 12.4 13.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4795 PF16043.5 GAP87674.1 - 0.31 10.6 26.7 2.2 7.8 17.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) MAD PF05557.13 GAP87674.1 - 0.34 9.2 30.1 0.4 9.0 30.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Seryl_tRNA_N PF02403.22 GAP87674.1 - 0.36 11.1 27.3 0.18 12.0 0.8 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 GAP87674.1 - 0.36 10.6 33.0 0.16 11.8 1.7 4.4 1 1 2 4 4 4 0 Septum formation initiator Rab5-bind PF09311.11 GAP87674.1 - 0.37 10.1 26.4 0.21 11.0 16.0 2.2 1 1 1 2 2 2 0 Rabaptin-like protein TMF_DNA_bd PF12329.8 GAP87674.1 - 0.37 10.8 36.1 1.7 8.7 2.0 3.8 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 GAP87674.1 - 0.39 9.7 24.8 0.11 11.5 12.9 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_CLD_2 PF14197.6 GAP87674.1 - 0.39 10.8 32.1 9.9 6.3 14.4 4.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 HAP1_N PF04849.13 GAP87674.1 - 0.47 9.6 31.0 18 4.4 31.0 2.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region BST2 PF16716.5 GAP87674.1 - 0.53 10.9 28.4 0.13 12.9 9.1 3.2 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Jnk-SapK_ap_N PF09744.9 GAP87674.1 - 0.71 10.1 33.3 0.38 11.0 21.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CASP_C PF08172.12 GAP87674.1 - 0.75 9.1 23.1 0.11 11.9 1.4 2.1 1 1 1 2 2 2 0 CASP C terminal TANGO2 PF05742.12 GAP87674.1 - 0.79 9.7 6.9 1.3 9.0 6.8 1.5 1 1 0 1 1 1 0 Transport and Golgi organisation 2 XhlA PF10779.9 GAP87674.1 - 0.82 9.9 23.9 0.5 10.6 1.2 4.1 2 1 1 4 4 4 0 Haemolysin XhlA CENP-H PF05837.12 GAP87674.1 - 0.86 10.0 28.9 1.9 8.9 0.9 3.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4686 PF15742.5 GAP87674.1 - 0.9 8.6 33.6 13 4.8 19.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) SHE3 PF17078.5 GAP87674.1 - 0.99 9.1 25.6 0.22 11.2 2.4 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 FapA PF03961.13 GAP87674.1 - 1 7.9 26.1 0.56 8.8 8.6 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A FAM76 PF16046.5 GAP87674.1 - 1.1 8.6 24.2 2.4 7.4 9.3 2.1 1 1 1 2 2 2 0 FAM76 protein Shugoshin_N PF07558.11 GAP87674.1 - 1.2 9.1 0.1 1.2 9.1 0.1 3.9 6 0 0 6 6 3 0 Shugoshin N-terminal coiled-coil region MIS13 PF08202.11 GAP87674.1 - 1.4 8.2 21.6 7.3 5.8 7.6 2.1 1 1 1 2 2 2 0 Mis12-Mtw1 protein family YabA PF06156.13 GAP87674.1 - 1.5 9.5 25.6 11 6.7 1.1 3.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF2203 PF09969.9 GAP87674.1 - 1.9 9.2 19.3 0.47 11.2 4.5 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4482 PF14818.6 GAP87674.1 - 2 9.3 24.2 0.12 13.2 3.6 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4482) Rootletin PF15035.6 GAP87674.1 - 2.3 8.2 31.6 0.73 9.8 9.3 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.12 GAP87674.1 - 2.4 8.3 36.7 3.1 7.9 11.5 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cep57_MT_bd PF06657.13 GAP87674.1 - 2.7 8.5 23.5 0.96 9.9 5.2 3.7 1 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CLZ PF16526.5 GAP87674.1 - 2.9 8.3 27.8 1.8 9.0 2.7 3.5 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3584 PF12128.8 GAP87674.1 - 3.2 5.1 28.5 8.4 3.8 28.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) TRAF_BIRC3_bd PF16673.5 GAP87674.1 - 3.4 7.5 12.8 1.2 8.9 0.9 3.1 2 2 2 4 4 3 0 TNF receptor-associated factor BIRC3 binding domain CtIP_N PF10482.9 GAP87674.1 - 3.6 7.7 24.3 0.11 12.6 5.7 2.7 1 1 1 2 2 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF2730 PF10805.8 GAP87674.1 - 4.4 7.4 15.0 0.24 11.5 2.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Fmp27_WPPW PF10359.9 GAP87674.1 - 5.1 5.8 27.0 0.97 8.2 11.0 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.6 GAP87674.1 - 6.8 6.0 22.9 78 2.5 23.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 GAP87674.1 - 6.8 7.3 21.0 30 5.2 10.8 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Mod_r PF07200.13 GAP87674.1 - 7.3 6.7 28.8 11 6.1 4.3 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PI3K_P85_iSH2 PF16454.5 GAP87674.1 - 8.5 6.0 27.4 48 3.5 8.9 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AAA_13 PF13166.6 GAP87674.1 - 8.9 4.8 24.5 32 3.0 24.5 1.8 1 1 0 1 1 1 0 AAA domain PRKG1_interact PF15898.5 GAP87674.1 - 9.3 7.2 30.5 3.1 8.7 13.1 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Ax_dynein_light PF10211.9 GAP87674.1 - 9.8 6.1 33.0 7.3 6.5 5.8 3.6 1 1 2 3 3 3 0 Axonemal dynein light chain Nop25 PF09805.9 GAP87675.1 - 5.8e-42 143.4 15.1 5.8e-42 143.4 15.1 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) GvpL_GvpF PF06386.11 GAP87675.1 - 0.058 13.3 4.1 0.12 12.3 4.1 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PIN_5 PF08745.11 GAP87675.1 - 0.29 10.5 2.9 0.52 9.7 2.9 1.3 1 0 0 1 1 1 0 PINc domain ribonuclease APH PF01636.23 GAP87676.1 - 9.8e-09 35.5 0.1 1.9e-07 31.2 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP87676.1 - 2.3e-05 24.1 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 GAP87676.1 - 0.036 13.4 0.0 0.078 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain ATP-synt_S1 PF05827.12 GAP87677.1 - 2.2e-05 24.3 0.1 3.9e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Pro_isomerase PF00160.21 GAP87678.1 - 4.9e-49 166.6 0.3 6.3e-49 166.3 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 GAP87679.1 - 3.9e-18 66.1 1.5 4.4e-16 59.4 1.5 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_M19 PF01244.21 GAP87680.1 - 2.3e-38 132.2 0.0 5.3e-29 101.4 0.0 2.0 1 1 1 2 2 2 2 Membrane dipeptidase (Peptidase family M19) Tom22 PF04281.13 GAP87681.1 - 3e-51 172.8 0.4 3.6e-51 172.6 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Nha1_C PF08619.10 GAP87682.1 - 9.6e-110 367.9 25.1 1.9e-109 367.0 25.1 1.5 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 GAP87682.1 - 3.1e-76 256.6 21.7 3.7e-76 256.4 21.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Colicin_E5 PF12106.8 GAP87682.1 - 0.004 17.4 0.6 0.079 13.3 0.1 2.5 2 0 0 2 2 2 1 Colicin E5 ribonuclease domain DUF21 PF01595.20 GAP87682.1 - 0.93 9.2 8.8 0.27 10.9 1.5 2.5 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain YrhC PF14143.6 GAP87682.1 - 1.2 9.3 8.7 0.32 11.1 0.5 3.1 3 0 0 3 3 3 0 YrhC-like protein FAD_binding_4 PF01565.23 GAP87683.1 - 1.5e-24 86.3 0.0 2.5e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 GAP87683.1 - 6.9e-13 48.8 0.0 1.1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain HPP PF04982.13 GAP87684.1 - 4.2e-37 127.0 9.2 1.2e-36 125.6 7.3 2.1 2 0 0 2 2 2 1 HPP family FUSC_2 PF13515.6 GAP87684.1 - 0.083 13.0 10.7 0.37 10.9 8.7 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein-like CoA_binding_3 PF13727.6 GAP87684.1 - 0.75 9.8 6.8 0.27 11.2 2.4 2.1 1 1 1 2 2 2 0 CoA-binding domain DUF2955 PF11168.8 GAP87684.1 - 3.9 7.3 10.8 1.3 8.9 3.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2955) adh_short PF00106.25 GAP87685.1 - 2.1e-23 82.8 0.0 8.4e-22 77.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87685.1 - 9.2e-16 58.1 0.0 7.5e-15 55.1 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87685.1 - 4.8e-07 29.9 0.0 8.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP87685.1 - 3.6e-05 23.3 0.1 0.00013 21.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP87685.1 - 0.0012 18.3 0.2 0.0078 15.7 0.0 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAP87685.1 - 0.086 12.7 0.1 0.17 11.7 0.1 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Scytalone_dh PF02982.14 GAP87686.1 - 2.8e-91 303.5 0.8 3.2e-91 303.3 0.8 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 GAP87686.1 - 3.1e-09 37.0 0.4 4.1e-09 36.6 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain LPD23 PF18838.1 GAP87686.1 - 0.021 14.5 0.5 0.043 13.6 0.5 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 DUF3142 PF11340.8 GAP87686.1 - 0.14 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) RicinB_lectin_2 PF14200.6 GAP87687.1 - 8.7e-25 87.3 8.7 3.9e-17 62.7 2.7 2.2 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 GAP87687.1 - 1.9e-07 31.4 0.1 9e-07 29.2 0.1 2.1 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain FLgD_tudor PF13861.6 GAP87687.1 - 0.86 9.9 3.6 18 5.7 0.1 3.0 3 0 0 3 3 3 0 FlgD Tudor-like domain Med22 PF06179.12 GAP87689.1 - 1e-16 61.0 0.6 1.3e-16 60.7 0.6 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex SOGA PF11365.8 GAP87689.1 - 0.055 14.6 0.9 4 8.6 0.9 2.2 1 1 0 1 1 1 0 Protein SOGA PseudoU_synth_1 PF01416.20 GAP87690.1 - 4.1e-11 43.3 0.0 9.9e-10 38.9 0.0 2.7 3 0 0 3 3 3 1 tRNA pseudouridine synthase SET PF00856.28 GAP87692.1 - 3.2e-08 34.1 0.0 2.9e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 GAP87692.1 - 1e-05 25.5 16.7 1e-05 25.5 16.7 2.7 2 1 0 2 2 2 1 MYND finger MFS_1 PF07690.16 GAP87693.1 - 6.8e-46 156.8 51.7 3.6e-39 134.7 39.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF726 PF05277.12 GAP87694.1 - 5.8e-125 416.8 0.9 7.1e-125 416.5 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 GAP87694.1 - 0.002 18.3 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.11 GAP87694.1 - 0.034 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_8 PF06259.12 GAP87694.1 - 0.086 12.5 0.1 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase Cutinase PF01083.22 GAP87694.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Cutinase TcdA_TcdB_pore PF12920.7 GAP87694.1 - 0.83 7.8 2.3 1.2 7.3 2.3 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Mpv17_PMP22 PF04117.12 GAP87695.1 - 9.2e-17 61.0 0.2 2e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family E1-E2_ATPase PF00122.20 GAP87696.1 - 6.5e-47 159.4 4.7 6.5e-47 159.4 4.7 2.5 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 GAP87696.1 - 1.1e-20 74.8 0.9 2.1e-20 73.9 0.9 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAP87696.1 - 0.00033 21.1 0.0 0.035 14.6 0.0 2.5 2 0 0 2 2 2 1 Heavy-metal-associated domain APG17 PF04108.12 GAP87697.1 - 3e-128 428.3 10.0 3.4e-128 428.2 10.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Gp-FAR-1 PF05823.12 GAP87697.1 - 0.00078 19.8 0.3 3.6 7.9 0.0 3.6 2 1 1 3 3 3 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) KxDL PF10241.9 GAP87697.1 - 0.0012 19.1 11.9 0.069 13.4 0.3 3.7 3 0 0 3 3 3 2 Uncharacterized conserved protein DUF745 PF05335.13 GAP87697.1 - 0.011 15.4 0.4 0.011 15.4 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF745) CdvA PF18822.1 GAP87697.1 - 0.012 15.5 4.3 0.31 10.9 0.2 3.4 3 0 0 3 3 3 0 CdvA-like coiled-coil domain CTP_transf_like PF01467.26 GAP87697.1 - 0.037 14.2 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Cytidylyltransferase-like DUF5390 PF17365.2 GAP87697.1 - 0.041 14.2 0.0 4 7.7 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5390) DUF4795 PF16043.5 GAP87697.1 - 0.042 13.5 10.5 0.057 13.0 2.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) IL3 PF02059.15 GAP87697.1 - 0.045 13.8 1.3 0.13 12.3 0.1 2.2 2 0 0 2 2 2 0 Interleukin-3 Tropomyosin_1 PF12718.7 GAP87697.1 - 0.086 13.0 7.6 0.99 9.6 2.9 2.8 3 0 0 3 3 2 0 Tropomyosin like ParB PF08775.10 GAP87697.1 - 0.11 13.0 1.4 11 6.6 0.1 2.7 2 0 0 2 2 2 0 ParB family Spc7 PF08317.11 GAP87697.1 - 0.14 11.0 10.6 0.12 11.2 3.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 GAP87697.1 - 0.18 11.8 7.3 3.2 7.8 1.4 3.3 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 GAP87697.1 - 0.2 12.1 5.0 1.4 9.5 0.5 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.11 GAP87697.1 - 0.21 11.4 4.3 1.4 8.8 0.4 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ApoO PF09769.9 GAP87697.1 - 0.28 11.1 1.5 16 5.5 0.0 3.5 4 0 0 4 4 4 0 Apolipoprotein O DUF4600 PF15372.6 GAP87697.1 - 0.47 10.9 4.1 5.2 7.5 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) EIF4E-T PF10477.9 GAP87697.1 - 0.47 9.2 4.7 0.3 9.9 0.3 2.3 2 1 1 3 3 3 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E FliD_N PF02465.18 GAP87697.1 - 0.47 11.2 2.9 38 5.1 0.1 3.5 4 0 0 4 4 3 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.10 GAP87697.1 - 0.68 10.1 9.9 0.35 11.1 2.1 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family LXG PF04740.12 GAP87697.1 - 1.2 8.8 6.6 4 7.1 0.2 2.8 3 0 0 3 3 2 0 LXG domain of WXG superfamily Prefoldin_2 PF01920.20 GAP87697.1 - 1.2 9.1 9.4 5.2 7.1 0.9 2.9 3 0 0 3 3 2 0 Prefoldin subunit JIP_LZII PF16471.5 GAP87697.1 - 1.3 9.2 7.4 2.2 8.5 1.7 3.0 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II EzrA PF06160.12 GAP87697.1 - 1.5 6.9 11.2 0.28 9.3 3.5 2.5 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Sec34 PF04136.15 GAP87697.1 - 2.5 8.0 7.2 0.47 10.3 1.0 2.8 3 0 0 3 3 3 0 Sec34-like family Fez1 PF06818.15 GAP87697.1 - 4.7 7.6 11.9 1.9 8.9 1.6 2.6 2 1 0 2 2 2 0 Fez1 THOC7 PF05615.13 GAP87697.1 - 5 7.4 10.1 1.3 9.3 0.7 2.7 2 1 0 2 2 2 0 Tho complex subunit 7 CCDC-167 PF15188.6 GAP87697.1 - 7.9 6.9 8.7 5.6 7.4 0.5 3.6 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 KLRAQ PF10205.9 GAP87697.1 - 9.5 6.5 12.4 2.4 8.4 0.2 3.3 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein Enkurin PF13864.6 GAP87697.1 - 9.8 6.7 7.1 3.2 8.3 0.2 3.2 3 1 0 3 3 2 0 Calmodulin-binding Flavokinase PF01687.17 GAP87698.1 - 1.8e-10 41.1 0.0 3.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase MFS_1 PF07690.16 GAP87701.1 - 5.8e-31 107.7 31.2 5.8e-31 107.7 31.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4267 PF14087.6 GAP87701.1 - 2.4 8.2 9.6 0.29 11.2 1.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4267) MMPL PF03176.15 GAP87701.1 - 8.3 5.2 12.1 0.67 8.8 1.5 2.4 2 0 0 2 2 2 0 MMPL family Ferric_reduct PF01794.19 GAP87702.1 - 4.3e-17 62.4 9.8 4.3e-17 62.4 9.8 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAP87702.1 - 7.6e-09 35.6 0.0 1.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 GAP87702.1 - 1.5e-07 31.7 0.0 0.00042 20.5 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DUF218 PF02698.17 GAP87703.1 - 2.1e-24 86.0 0.0 3.1e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain DUF1866 PF08952.11 GAP87703.1 - 0.037 13.9 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Methyltransf_25 PF13649.6 GAP87704.1 - 2.9e-10 40.7 0.0 1.8e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP87704.1 - 1.4e-09 38.0 0.0 1.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP87704.1 - 1.2e-08 35.6 0.0 4.1e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP87704.1 - 5.8e-07 30.1 0.0 1.3e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 GAP87704.1 - 0.00042 20.5 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 GAP87704.1 - 0.21 11.5 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAP87705.1 - 2e-19 70.0 0.0 2.9e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP87705.1 - 2.8e-09 37.6 0.0 1.3e-08 35.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 GAP87705.1 - 3.8e-06 27.1 0.0 8.2e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 GAP87705.1 - 8.4e-06 25.6 0.0 8.9e-05 22.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAP87705.1 - 8.3e-05 22.1 0.0 0.00023 20.7 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 GAP87705.1 - 0.00013 22.6 0.0 0.001 19.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP87705.1 - 0.0086 16.7 0.0 0.024 15.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP87705.1 - 0.0087 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain HoxA13_N PF12284.8 GAP87705.1 - 0.054 14.1 6.3 0.055 14.1 4.7 1.8 1 1 1 2 2 2 0 Hox protein A13 N terminal ketoacyl-synt PF00109.26 GAP87706.1 - 1.3e-75 254.3 0.0 2.4e-75 253.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP87706.1 - 4.9e-58 196.0 0.0 8.8e-57 191.9 0.0 3.0 3 0 0 3 3 2 1 KR domain PS-DH PF14765.6 GAP87706.1 - 5.6e-44 150.6 0.0 8.5e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP87706.1 - 1.6e-43 149.4 0.0 2.7e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP87706.1 - 9.5e-33 112.7 0.0 6e-32 110.1 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAP87706.1 - 3.5e-18 66.2 0.0 1.2e-17 64.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 GAP87706.1 - 6.4e-14 52.0 0.0 5.6e-13 49.0 0.0 2.7 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 GAP87706.1 - 1.4e-13 51.1 0.0 3.9e-13 49.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 GAP87706.1 - 1.6e-11 44.1 0.0 1.1e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 GAP87706.1 - 3.6e-11 43.6 0.0 2.4e-10 41.0 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAP87706.1 - 3e-10 40.5 0.0 2.7e-08 34.2 0.0 2.6 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 GAP87706.1 - 5.3e-10 39.3 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP87706.1 - 2.3e-09 37.8 0.0 1.4e-08 35.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 GAP87706.1 - 2.5e-09 38.3 0.0 4.6e-08 34.2 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 GAP87706.1 - 9e-08 32.0 0.1 4.7e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 GAP87706.1 - 2.7e-07 30.8 0.1 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 GAP87706.1 - 4.5e-05 22.9 0.0 9.5e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 GAP87706.1 - 7.4e-05 22.2 0.0 0.00018 21.0 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 GAP87706.1 - 0.00039 20.2 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase ADH_N PF08240.12 GAP87706.1 - 0.00063 19.6 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF938 PF06080.12 GAP87706.1 - 0.1 12.4 0.3 2.1 8.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_28 PF02636.17 GAP87706.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 GAP87706.1 - 0.16 13.0 0.0 0.75 10.8 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase domain Cofilin_ADF PF00241.20 GAP87707.1 - 4.8e-28 97.4 0.0 2.1e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.27 GAP87708.1 - 4.8e-67 221.9 0.6 2.9e-21 75.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 GAP87709.1 - 2.8e-43 145.0 13.8 4.4e-08 33.6 0.1 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 GAP87709.1 - 3e-12 46.3 1.2 6.8e-12 45.1 1.2 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 GAP87709.1 - 2e-10 40.8 0.2 0.017 15.4 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 GAP87709.1 - 4.3e-08 32.9 1.5 4.3e-08 32.9 1.5 2.3 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 GAP87709.1 - 1.8e-06 26.9 6.4 0.41 9.2 0.1 4.5 3 1 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 GAP87709.1 - 0.0012 18.3 0.0 0.0066 15.8 0.0 1.9 2 1 1 3 3 3 2 WD40-like domain eIF2A PF08662.11 GAP87709.1 - 0.021 14.7 0.0 3.2 7.6 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A F-box_4 PF15966.5 GAP87709.1 - 0.024 14.5 1.8 0.079 12.9 1.8 1.9 1 1 0 1 1 1 0 F-box TcfC PF16967.5 GAP87709.1 - 0.033 13.7 0.0 0.43 10.1 0.0 2.4 2 0 0 2 2 2 0 E-set like domain Glyco_hydro_47 PF01532.20 GAP87711.1 - 7.1e-163 542.7 0.0 8.3e-163 542.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TauD PF02668.16 GAP87712.1 - 8.4e-32 111.0 0.3 1.3e-31 110.4 0.3 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 GAP87712.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 CsiD Mito_carr PF00153.27 GAP87713.1 - 1.3e-16 60.3 0.9 1.7e-10 40.7 0.0 3.8 3 1 0 3 3 3 2 Mitochondrial carrier protein DUF3818 PF12825.7 GAP87714.1 - 1.2e-51 175.7 1.9 5.3e-34 117.7 0.5 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 GAP87714.1 - 1.4e-30 106.0 0.0 3.7e-30 104.6 0.0 1.8 1 0 0 1 1 1 1 PX-associated PEX11 PF05648.14 GAP87714.1 - 0.046 13.2 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Metal_resist PF13801.6 GAP87714.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.1 2 0 0 2 2 2 0 Heavy-metal resistance Aspzincin_M35 PF14521.6 GAP87715.1 - 3.5e-33 115.2 2.2 3.5e-33 115.2 2.2 1.8 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 GAP87715.1 - 8.9e-33 113.6 14.9 1.1e-32 113.3 14.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.6 GAP87715.1 - 3.5e-06 26.8 0.7 3.5e-06 26.8 0.7 1.7 2 0 0 2 2 2 1 Putative peptidase family SBE2 PF17076.5 GAP87715.1 - 0.21 9.7 3.5 0.27 9.4 3.5 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation Glyco_hydro_3_C PF01915.22 GAP87716.1 - 3.2e-40 138.3 0.0 1e-39 136.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAP87716.1 - 4e-37 128.3 0.0 7.4e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAP87716.1 - 8.3e-21 73.9 0.1 1.5e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain MARVEL PF01284.23 GAP87717.1 - 2.8e-20 72.8 5.9 4e-20 72.3 5.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain PBP PF01161.20 GAP87718.1 - 1.7e-09 38.0 0.0 3e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-C3HC4_2 PF13923.6 GAP87718.1 - 0.00053 19.8 0.4 0.00053 19.8 0.4 3.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP87718.1 - 0.0014 18.6 0.2 0.0014 18.6 0.2 3.3 4 1 0 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 GAP87718.1 - 0.0016 18.7 0.3 0.0016 18.7 0.3 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 GAP87718.1 - 0.0024 17.7 0.9 0.011 15.6 0.3 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP87718.1 - 0.011 15.7 0.1 0.011 15.7 0.1 2.6 3 0 0 3 3 3 0 RING-type zinc-finger Prok-RING_4 PF14447.6 GAP87718.1 - 0.044 13.7 0.9 0.044 13.7 0.9 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAP87718.1 - 0.14 12.4 0.3 0.14 12.4 0.3 2.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 GAP87718.1 - 5.7 6.9 11.1 0.48 10.3 0.1 3.6 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) VIT PF08487.10 GAP87719.1 - 7.7e-32 109.8 0.1 1.5e-31 108.9 0.1 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 GAP87719.1 - 9e-27 93.9 0.0 1.7e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 GAP87719.1 - 1.1e-10 41.2 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 GAP87719.1 - 6.6e-10 39.5 0.0 1.3e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAP87719.1 - 1.7e-07 31.9 0.0 4.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain RPE65 PF03055.15 GAP87720.1 - 3.1e-90 303.6 0.0 4.7e-90 303.0 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF1264 PF06884.11 GAP87720.1 - 2.7e-29 101.9 2.4 2.2e-28 99.0 2.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1264) SnoaL_4 PF13577.6 GAP87720.1 - 1.7e-27 96.0 1.2 1e-26 93.6 0.5 2.5 2 0 0 2 2 2 1 SnoaL-like domain DUF1192 PF06698.11 GAP87720.1 - 0.1 12.7 0.9 0.22 11.6 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DivIC PF04977.15 GAP87720.1 - 0.43 10.4 1.8 0.43 10.4 0.2 1.8 2 0 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.6 GAP87720.1 - 0.9 10.0 2.3 2 8.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) APH PF01636.23 GAP87721.1 - 3.1e-07 30.6 0.1 1.3e-06 28.5 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Arf PF00025.21 GAP87722.1 - 3.4e-68 228.5 0.8 3.8e-68 228.4 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 GAP87722.1 - 1.4e-13 50.8 0.0 1.6e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP87722.1 - 2.2e-13 50.5 0.0 3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAP87722.1 - 1.7e-12 47.2 0.6 3.5e-07 29.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 GAP87722.1 - 3.8e-10 39.5 0.0 4.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAP87722.1 - 8.4e-09 35.5 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 GAP87722.1 - 3.1e-08 33.3 0.0 3.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 GAP87722.1 - 0.00021 20.9 0.0 0.0086 15.6 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 GAP87722.1 - 0.0033 17.4 0.0 0.059 13.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain FeoB_N PF02421.18 GAP87722.1 - 0.057 12.9 0.2 0.14 11.6 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Hamartin PF04388.12 GAP87724.1 - 3.1 6.4 10.3 3.7 6.1 10.3 1.1 1 0 0 1 1 1 0 Hamartin protein APH PF01636.23 GAP87725.1 - 8e-09 35.8 0.0 1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAP87725.1 - 0.0002 20.8 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 GAP87725.1 - 0.016 14.4 0.0 0.17 11.0 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase Choline_kinase PF01633.20 GAP87725.1 - 0.018 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 GAP87725.1 - 0.07 12.0 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) CTU2 PF10288.9 GAP87726.1 - 3.6e-10 40.1 0.0 1.7e-08 34.7 0.0 2.8 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 GAP87726.1 - 0.044 13.5 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Mito_carr PF00153.27 GAP87727.1 - 1.3e-44 150.0 0.4 2.9e-18 65.6 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FHA PF00498.26 GAP87728.1 - 3e-15 56.3 0.0 6.5e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 GAP87728.1 - 1.9e-13 49.8 5.6 3.5e-13 49.0 5.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 GAP87728.1 - 7.7e-07 29.3 9.3 1.3e-06 28.6 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAP87728.1 - 0.0011 18.7 8.4 0.002 18.0 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP87728.1 - 0.0059 16.5 5.4 0.0098 15.8 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Yop-YscD_cpl PF16697.5 GAP87728.1 - 0.0087 16.4 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 GAP87728.1 - 0.013 15.3 8.7 0.025 14.4 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP87728.1 - 0.037 14.1 7.5 0.074 13.1 7.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAP87728.1 - 0.099 12.7 2.7 0.17 11.9 2.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 GAP87728.1 - 0.16 12.3 1.5 0.33 11.2 1.5 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-rbx1 PF12678.7 GAP87728.1 - 0.39 11.1 9.6 0.95 9.8 9.6 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 GAP87728.1 - 0.46 10.4 5.7 0.87 9.5 5.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 GAP87728.1 - 1.3 9.3 6.1 13 6.1 5.6 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 GAP87728.1 - 3.1 8.2 5.0 5.6 7.4 5.0 1.4 1 0 0 1 1 1 0 RING-like domain Peptidase_M16_C PF05193.21 GAP87729.1 - 1.1e-50 172.2 0.0 2.1e-50 171.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAP87729.1 - 1.1e-38 132.5 0.0 2.6e-38 131.3 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Bac_rhamnosid6H PF17389.2 GAP87730.1 - 2.8e-13 49.9 0.1 4.3e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 GAP87730.1 - 4.1e-11 42.5 0.1 1e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 GAP87730.1 - 8e-06 25.0 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.11 GAP87730.1 - 0.021 14.8 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain DUF608 PF04685.13 GAP87730.1 - 0.045 12.9 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region ELFV_dehydrog PF00208.21 GAP87731.1 - 7.9e-65 219.0 0.0 1.2e-64 218.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 GAP87731.1 - 4.5e-20 70.9 0.0 1.5e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 GAP87731.1 - 0.026 14.4 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Aminotran_5 PF00266.19 GAP87732.1 - 6.1e-10 38.6 0.0 1.3e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAP87732.1 - 0.0001 21.0 0.0 0.00024 19.8 0.0 1.6 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 GAP87732.1 - 0.0014 18.0 0.0 0.0047 16.3 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family zf-CHY PF05495.12 GAP87733.1 - 5.9e-12 45.9 22.1 1.1e-11 45.0 22.1 1.4 1 0 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.10 GAP87733.1 - 2.3 8.4 17.7 3.7 7.8 9.4 2.6 1 1 1 2 2 2 0 Zinc ribbon domain RNA_POL_M_15KD PF02150.16 GAP87733.1 - 8.3 6.4 13.5 16 5.5 1.8 3.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit HypA PF01155.19 GAP87733.1 - 9.9 6.2 14.2 94 3.1 14.2 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Proteasome PF00227.26 GAP87734.1 - 3.3e-56 189.8 0.3 5e-56 189.2 0.3 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAP87734.1 - 1.1e-11 44.2 0.4 3.6e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn_clus PF00172.18 GAP87735.1 - 9.3e-07 28.9 10.3 1.7e-06 28.1 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 GAP87736.1 - 2e-40 139.0 0.0 2.6e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.13 GAP87737.1 - 1.5e-30 105.1 0.3 1.8e-30 104.8 0.3 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Ribonucleas_3_3 PF14622.6 GAP87737.1 - 0.024 14.8 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like zf-rbx1 PF12678.7 GAP87738.1 - 2.3e-24 85.4 13.8 3.3e-24 84.9 13.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAP87738.1 - 1.4e-16 60.3 10.2 1.9e-16 59.9 10.2 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 GAP87738.1 - 1.1e-05 25.7 15.2 0.0004 20.7 15.2 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAP87738.1 - 0.0049 16.7 15.5 0.0083 16.0 10.0 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP87738.1 - 0.0095 15.8 13.3 0.17 11.8 13.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAP87738.1 - 0.31 10.8 15.8 26 4.7 15.8 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 GAP87738.1 - 0.43 10.5 11.5 1.3 9.0 5.2 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP87738.1 - 0.72 9.9 8.0 2.7 8.1 8.0 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 GAP87738.1 - 1.2 9.4 9.5 7.6 6.8 9.7 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAP87738.1 - 3 7.5 16.5 0.72 9.5 6.4 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type PNRC PF15365.6 GAP87739.1 - 8e-08 31.9 8.8 8e-08 31.9 8.8 3.9 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif Tyr-DNA_phospho PF06087.12 GAP87740.1 - 1.2e-87 294.5 0.0 1.5e-87 294.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 GAP87740.1 - 0.0026 17.5 1.1 0.0026 17.5 1.1 3.6 4 0 0 4 4 4 1 Ubiquitin interaction motif FAM110_C PF14160.6 GAP87740.1 - 0.0069 17.4 0.1 0.18 12.9 0.0 2.6 2 1 0 2 2 2 1 Centrosome-associated C terminus PLDc_2 PF13091.6 GAP87740.1 - 0.0074 16.2 0.0 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 PLD-like domain Gti1_Pac2 PF09729.9 GAP87741.1 - 9.7e-61 205.0 0.0 1.5e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.21 GAP87742.1 - 4e-12 46.7 0.5 4e-12 46.7 0.5 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.22 GAP87743.1 - 1.2e-156 521.8 0.0 1.5e-156 521.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 GAP87743.1 - 3.6e-65 220.1 0.0 5.4e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 GAP87743.1 - 1.6e-05 24.5 4.7 2.2e-05 24.0 4.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP87743.1 - 2e-05 24.0 0.1 3.8e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAP87743.1 - 0.00093 18.5 1.2 0.0024 17.2 1.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 GAP87743.1 - 0.0014 17.7 2.1 0.0014 17.7 2.1 2.0 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 GAP87743.1 - 0.015 14.1 1.6 0.18 10.5 0.6 2.2 2 0 0 2 2 2 0 HI0933-like protein DUF3602 PF12223.8 GAP87744.1 - 3.2e-08 34.0 15.5 9.6e-05 22.9 4.9 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) BRD4_CDT PF17105.5 GAP87744.1 - 0.036 13.7 2.6 0.085 12.5 2.6 1.6 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Ribosomal_L24e PF01246.20 GAP87745.1 - 5.4e-32 109.8 5.2 1.5e-31 108.4 5.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e DnaJ PF00226.31 GAP87746.1 - 2.5e-06 27.5 0.0 3.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 GAP87746.1 - 2.9e-06 27.3 0.0 3.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Pam16 DUF3918 PF13056.6 GAP87746.1 - 1.1 8.9 3.7 0.51 10.0 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Ku_PK_bind PF08785.11 GAP87748.1 - 7e-34 116.5 0.1 1.7e-33 115.3 0.1 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 GAP87748.1 - 1.6e-28 99.8 0.0 2.9e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 GAP87748.1 - 7.4e-15 55.3 0.0 1.3e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 GAP87748.1 - 5.6e-06 26.7 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2408 PF10303.9 GAP87748.1 - 0.087 13.4 0.1 0.22 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4149 PF13664.6 GAP87749.1 - 1.2e-25 89.8 1.7 1.2e-25 89.8 1.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DNA_pol_phi PF04931.13 GAP87749.1 - 0.02 13.0 0.2 0.026 12.6 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 GAP87749.1 - 0.037 14.5 1.3 0.048 14.1 1.3 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1772 PF08592.11 GAP87749.1 - 0.054 13.8 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Kinocilin PF15033.6 GAP87749.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.5 1 1 0 1 1 1 0 Kinocilin protein DUF4692 PF15763.5 GAP87749.1 - 1.7 9.1 4.1 2.5 8.5 4.1 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF1295 PF06966.12 GAP87751.1 - 8.3e-36 123.7 7.9 1e-35 123.4 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 GAP87751.1 - 0.056 13.9 0.6 0.6 10.6 0.0 2.5 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.20 GAP87752.1 - 1.6e-103 346.9 0.0 2.4e-97 326.6 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 GAP87752.1 - 1.4e-20 73.4 0.0 3.3e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Toprim domain RdRP_1 PF00680.20 GAP87752.1 - 0.075 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase Stb3 PF10330.9 GAP87753.1 - 2.1e-36 123.8 0.0 3.4e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein zf-C2H2 PF00096.26 GAP87755.1 - 7.9e-08 32.4 19.2 1.8e-05 24.9 3.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP87755.1 - 3.9e-05 23.9 3.8 3.9e-05 23.9 3.8 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP87755.1 - 4.1e-05 24.1 2.3 4.1e-05 24.1 2.3 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP87755.1 - 0.0015 18.8 1.0 0.0015 18.8 1.0 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAP87755.1 - 0.0017 18.3 1.8 0.0017 18.3 1.8 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 GAP87755.1 - 0.037 14.7 8.0 0.061 14.0 4.1 2.9 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 GAP87755.1 - 0.16 12.3 9.4 0.42 10.9 5.9 3.0 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-met PF12874.7 GAP87755.1 - 0.5 10.8 3.3 0.33 11.4 0.7 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 GAP87755.1 - 1.7 8.7 4.7 2 8.6 2.9 1.7 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_2 PF12756.7 GAP87755.1 - 2.3 8.6 9.3 9.2 6.7 7.4 2.7 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) ARS2 PF04959.13 GAP87755.1 - 2.8 8.3 10.1 1.8 8.9 3.7 3.0 3 0 0 3 3 3 0 Arsenite-resistance protein 2 DUF629 PF04780.12 GAP87755.1 - 3.1 6.2 8.0 1.2 7.6 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-TRAF PF02176.18 GAP87755.1 - 4.4 8.1 7.5 1.6 9.5 3.5 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2HE PF16278.5 GAP87755.1 - 5.5 7.5 7.0 1.7 9.1 2.9 2.2 1 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 GAP87755.1 - 6.7 6.6 8.7 1 9.2 2.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain EF-hand_6 PF13405.6 GAP87756.1 - 5.5e-11 41.5 0.6 5.5e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 GAP87756.1 - 2.8e-10 39.0 1.4 0.00068 19.0 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 GAP87756.1 - 2.9e-07 30.8 4.3 0.00018 21.9 0.6 2.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 GAP87756.1 - 2.7e-06 26.6 4.2 0.0072 15.8 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 GAP87756.1 - 4.5e-06 26.4 0.0 0.082 12.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 GAP87756.1 - 0.00071 19.9 0.0 0.94 9.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain TPR_1 PF00515.28 GAP87757.1 - 7.7e-39 130.0 10.5 3.3e-08 33.0 0.1 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 GAP87757.1 - 5.3e-34 113.6 16.1 1.1e-05 25.1 0.2 8.8 8 1 1 9 9 9 7 Tetratricopeptide repeat DnaJ PF00226.31 GAP87757.1 - 6.3e-27 93.5 4.7 8.6e-27 93.1 2.3 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.6 GAP87757.1 - 7.3e-27 92.8 13.2 1.8e-07 30.7 0.1 7.5 5 2 2 7 7 7 5 TPR repeat TPR_19 PF14559.6 GAP87757.1 - 1.4e-22 80.0 14.7 8.1e-11 42.3 0.0 6.3 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAP87757.1 - 2.3e-21 76.2 9.8 2.9e-06 27.8 0.2 6.0 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAP87757.1 - 4.3e-18 63.9 9.2 0.0088 16.2 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAP87757.1 - 1.5e-17 62.7 19.7 2.5e-05 24.7 0.2 8.1 5 2 4 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAP87757.1 - 2.1e-15 55.5 3.2 0.14 12.3 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAP87757.1 - 9.4e-14 50.7 14.5 0.0018 18.5 0.0 6.9 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAP87757.1 - 6.9e-13 48.7 12.8 0.00023 21.4 0.2 6.5 4 2 1 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 GAP87757.1 - 6.7e-12 45.4 11.2 0.00088 19.4 0.9 5.4 3 2 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP87757.1 - 1.8e-11 44.1 8.8 9.1e-05 22.6 0.1 4.2 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAP87757.1 - 9.6e-08 32.2 18.9 0.02 15.5 0.0 7.7 10 0 0 10 10 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAP87757.1 - 4.3e-07 29.4 9.1 0.00036 19.8 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAP87757.1 - 5.2e-06 26.2 13.0 0.5 10.3 0.1 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 GAP87757.1 - 1.5e-05 25.2 0.4 0.34 11.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 GAP87757.1 - 2.1e-05 25.0 4.8 0.29 11.6 0.1 4.5 2 2 2 4 4 4 2 Bacterial transcriptional activator domain NARP1 PF12569.8 GAP87757.1 - 0.0011 18.0 4.7 0.16 10.9 1.2 2.7 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 Coatomer_E PF04733.14 GAP87757.1 - 0.0036 16.8 1.0 0.13 11.6 0.0 3.0 3 1 0 3 3 3 1 Coatomer epsilon subunit SNAP PF14938.6 GAP87757.1 - 0.0036 16.8 9.3 0.019 14.4 0.8 3.6 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP NatB_MDM20 PF09797.9 GAP87757.1 - 0.0046 16.0 0.0 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit SHNi-TPR PF10516.9 GAP87757.1 - 0.0054 16.2 0.4 6.8 6.2 0.0 3.6 5 0 0 5 5 4 0 SHNi-TPR Alkyl_sulf_dimr PF14863.6 GAP87757.1 - 0.011 16.3 2.1 0.17 12.4 0.0 3.1 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_21 PF09976.9 GAP87757.1 - 0.014 15.1 5.0 2.3 7.9 0.1 3.5 3 2 1 4 4 4 0 Tetratricopeptide repeat-like domain DUF3856 PF12968.7 GAP87757.1 - 0.02 15.0 4.0 55 3.8 0.0 5.7 5 2 1 6 6 5 0 Domain of Unknown Function (DUF3856) ChAPs PF09295.10 GAP87757.1 - 0.022 13.8 0.2 0.046 12.7 0.0 1.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.18 GAP87757.1 - 0.022 14.8 4.2 10 6.3 0.0 4.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 GAP87757.1 - 0.039 13.3 2.2 0.47 9.8 0.7 2.9 1 1 1 2 2 2 0 MalT-like TPR region TPR_20 PF14561.6 GAP87757.1 - 0.12 12.7 12.1 0.51 10.7 0.2 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAP87757.1 - 0.13 12.3 2.4 26 5.0 0.0 4.4 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.12 GAP87757.1 - 0.7 9.9 2.5 0.95 9.5 0.1 2.5 4 0 0 4 4 1 0 Protein of unknown function (DUF627) MFS_1 PF07690.16 GAP87758.1 - 1.3e-17 63.8 38.2 4e-09 35.9 12.5 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily LacY_symp PF01306.19 GAP87758.1 - 8.7 5.0 12.0 0.14 10.9 2.5 2.5 3 0 0 3 3 3 0 LacY proton/sugar symporter MBOAT PF03062.19 GAP87759.1 - 7.8e-18 64.9 10.8 7.8e-18 64.9 10.8 2.0 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 GAP87759.1 - 0.00061 20.0 0.4 0.0017 18.6 0.4 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MDM31_MDM32 PF08118.11 GAP87759.1 - 0.061 12.0 0.6 0.092 11.4 0.6 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins WD40 PF00400.32 GAP87760.1 - 2.6e-30 104.0 26.9 2.9e-06 27.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP87760.1 - 5.5e-13 49.0 0.1 0.065 13.5 0.1 5.5 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAP87760.1 - 0.0042 17.0 0.0 4.3 7.2 0.0 3.3 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 GAP87760.1 - 0.2 9.9 0.0 0.86 7.8 0.0 1.5 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Endonuclease_NS PF01223.23 GAP87762.1 - 4.6e-65 219.6 0.0 5.9e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Formyl_trans_N PF00551.19 GAP87763.1 - 4.8e-35 120.9 0.0 5.8e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Zip PF02535.22 GAP87764.1 - 9.8e-30 103.9 6.2 1.1e-20 74.1 3.7 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter Tmemb_170 PF10190.9 GAP87766.1 - 5.4e-09 36.4 6.1 6.1e-09 36.2 6.1 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Hexapep_2 PF14602.6 GAP87767.1 - 2.6e-15 55.9 7.8 2.2e-10 40.1 1.2 3.2 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 GAP87767.1 - 1.5e-14 53.1 10.7 8.2e-11 41.2 1.9 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 GAP87767.1 - 2.1e-09 37.5 0.7 3.5e-09 36.7 0.7 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase ICMT PF04140.14 GAP87768.1 - 1.1e-28 99.4 0.0 2.8e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 GAP87768.1 - 2.3e-10 40.8 0.3 2.3e-10 40.8 0.3 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 GAP87768.1 - 0.0029 17.1 0.4 0.0037 16.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF3185 PF11381.8 GAP87768.1 - 0.0073 16.3 0.1 0.02 14.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3185) DnaJ PF00226.31 GAP87769.1 - 2.5e-15 56.4 0.1 7.7e-15 54.8 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 GAP87769.1 - 4e-13 49.1 0.0 1.3e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain Myb_DNA-binding PF00249.31 GAP87769.1 - 0.16 12.2 0.0 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF2407_C PF13373.6 GAP87769.1 - 0.23 11.6 1.2 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF2347 PF09804.9 GAP87770.1 - 2.5e-105 352.1 0.0 3.2e-105 351.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 GAP87770.1 - 8e-57 192.7 0.4 2e-56 191.4 0.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.10 GAP87770.1 - 7.4e-06 25.9 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 GAP87770.1 - 1e-05 24.4 0.0 0.00089 18.1 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 adh_short PF00106.25 GAP87771.1 - 5.5e-31 107.5 2.2 4.3e-21 75.3 0.2 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87771.1 - 5.1e-28 98.2 0.2 1.7e-13 50.7 0.4 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87771.1 - 5e-11 42.8 1.7 6.5e-10 39.2 1.7 2.3 1 1 0 1 1 1 1 KR domain Pyr_redox PF00070.27 GAP87771.1 - 0.0041 17.7 0.3 0.0081 16.7 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 GAP87771.1 - 0.0081 16.1 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAP87771.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAP87771.1 - 0.017 14.6 0.1 0.034 13.6 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAP87771.1 - 0.05 13.7 0.1 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 GAP87771.1 - 0.11 11.7 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LysM PF01476.20 GAP87772.1 - 1.7e-11 44.0 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 LysM domain Tyrosinase PF00264.20 GAP87774.1 - 1.6e-48 165.9 0.0 2.4e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase GST_C_3 PF14497.6 GAP87776.1 - 6.7e-30 103.2 0.0 1.4e-29 102.1 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAP87776.1 - 1.1e-05 25.5 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP87776.1 - 0.0001 22.3 0.1 0.00026 21.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAP87776.1 - 0.015 15.7 0.1 0.26 11.7 0.0 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 GAP87776.1 - 0.044 14.3 0.0 14 6.3 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Methyltransf_2 PF00891.18 GAP87778.1 - 3.4e-22 78.8 0.0 5e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAP87778.1 - 2.6e-09 37.6 0.3 8.1e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP87778.1 - 1.9e-05 24.5 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP87778.1 - 3.9e-05 24.3 0.0 0.0001 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP87778.1 - 0.00029 20.4 0.0 0.00059 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GAP87778.1 - 0.0029 17.5 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP87778.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.22 GAP87779.1 - 1.2e-44 152.8 0.0 1.7e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pribosyltran_N PF13793.6 GAP87779.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase ketoacyl-synt PF00109.26 GAP87780.1 - 1.7e-76 257.1 0.0 5.6e-76 255.5 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAP87780.1 - 1.1e-31 109.3 0.3 2.2e-31 108.3 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 GAP87780.1 - 1.2e-28 98.8 0.0 4.5e-28 97.0 0.0 2.0 2 0 0 2 2 1 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 GAP87780.1 - 6.9e-19 68.5 0.0 1.6e-17 64.0 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 GAP87780.1 - 1.3e-16 60.8 0.0 2.3e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 GAP87780.1 - 8.1e-15 55.4 0.0 2.6e-14 53.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 GAP87780.1 - 4.3e-14 52.6 1.1 9.3e-14 51.5 1.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 GAP87780.1 - 1.6e-13 50.8 0.0 4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 GAP87780.1 - 9.6e-13 48.4 2.6 2.5e-10 40.5 0.0 3.2 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Abhydrolase_3 PF07859.13 GAP87780.1 - 3.8e-10 40.0 0.0 1e-09 38.6 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 GAP87780.1 - 3.9e-09 37.1 0.0 1.1e-08 35.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.21 GAP87780.1 - 1.6e-07 31.0 0.0 0.00034 20.2 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thiolase_N PF00108.23 GAP87780.1 - 1.4e-05 24.6 0.1 2.7e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 GAP87780.1 - 4e-05 24.0 0.0 0.00013 22.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 GAP87780.1 - 5.6e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DLH PF01738.18 GAP87780.1 - 8.3e-05 22.2 0.0 0.55 9.7 0.0 3.4 3 0 0 3 3 3 1 Dienelactone hydrolase family Methyltransf_11 PF08241.12 GAP87780.1 - 9.9e-05 22.9 0.0 0.00032 21.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.7 GAP87780.1 - 0.00066 20.3 3.3 0.00066 20.3 3.3 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ubie_methyltran PF01209.18 GAP87780.1 - 0.0012 18.3 0.0 0.0026 17.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 GAP87780.1 - 0.0029 17.4 1.3 0.023 14.5 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thioesterase PF00975.20 GAP87780.1 - 0.0069 16.5 0.1 0.021 15.0 0.0 1.8 2 0 0 2 2 1 1 Thioesterase domain COesterase PF00135.28 GAP87780.1 - 0.007 15.3 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 GAP87780.1 - 0.014 14.6 0.1 0.097 11.9 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GAP87780.1 - 0.04 13.7 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 GAP87780.1 - 0.1 12.2 0.1 6.1 6.4 0.0 2.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Methyltransf_33 PF10017.9 GAP87780.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent LIP PF03583.14 GAP87780.1 - 0.13 11.5 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Secretory lipase Esterase PF00756.20 GAP87780.1 - 0.15 11.7 0.2 35 3.9 0.0 3.2 3 0 0 3 3 3 0 Putative esterase SET PF00856.28 GAP87781.1 - 4.3e-08 33.7 0.5 5.6e-07 30.1 0.1 2.5 2 1 0 3 3 3 1 SET domain Ribosomal_L14 PF00238.19 GAP87782.1 - 7.9e-47 158.3 3.5 9.3e-47 158.1 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_POL_M_15KD PF02150.16 GAP87783.1 - 5e-12 45.5 3.5 5e-12 45.5 3.5 1.8 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 GAP87783.1 - 0.028 14.4 8.3 0.33 11.0 2.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon Dicty_REP PF05086.12 GAP87783.1 - 0.47 8.4 1.6 0.59 8.0 1.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein C1_1 PF00130.22 GAP87783.1 - 0.96 9.4 7.6 0.24 11.3 1.6 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GFA PF04828.14 GAP87783.1 - 4.9 7.6 11.3 1.2 9.6 0.1 3.1 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Rotamase PF00639.21 GAP87784.1 - 4.4e-22 78.9 0.1 5.3e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 GAP87784.1 - 1.2e-15 58.0 0.0 1.4e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 GAP87784.1 - 0.0001 23.2 0.0 0.00012 22.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain sCache_2 PF17200.4 GAP87784.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Single Cache domain 2 LrgB PF04172.16 GAP87785.1 - 1.1e-29 103.6 13.0 2.4e-20 73.0 0.8 3.3 3 0 0 3 3 3 2 LrgB-like family LrgA PF03788.14 GAP87785.1 - 7.2e-05 22.7 1.0 7.2e-05 22.7 1.0 2.2 2 0 0 2 2 2 1 LrgA family NMO PF03060.15 GAP87785.1 - 0.077 12.4 0.4 0.12 11.8 0.4 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DUF4131 PF13567.6 GAP87785.1 - 5.6 6.6 10.4 1.1 8.9 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) FAM176 PF14851.6 GAP87787.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 FAM176 family MRAP PF15183.6 GAP87787.1 - 0.16 11.9 0.3 0.22 11.5 0.3 1.3 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family HemY_N PF07219.13 GAP87787.1 - 0.99 9.6 5.4 3 8.1 5.4 1.8 1 1 0 1 1 1 0 HemY protein N-terminus Atrophin-1 PF03154.15 GAP87787.1 - 1.6 6.9 7.3 1.9 6.7 7.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family Egh16-like PF11327.8 GAP87788.1 - 2.2e-69 233.5 8.7 2.9e-69 233.2 8.7 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor DUF937 PF06078.11 GAP87788.1 - 0.15 12.7 9.6 0.28 11.8 9.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) adh_short PF00106.25 GAP87789.1 - 5.5e-28 97.8 0.0 1.5e-27 96.3 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87789.1 - 5.7e-17 62.1 0.0 3e-16 59.7 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87789.1 - 2.7e-09 37.2 0.2 6.3e-09 36.0 0.1 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 GAP87789.1 - 0.0057 16.2 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP87789.1 - 0.084 12.8 0.6 0.26 11.1 0.6 1.8 1 1 0 1 1 1 0 NAD(P)H-binding DHHC PF01529.20 GAP87790.1 - 1.4e-35 122.3 12.1 1.4e-35 122.3 12.1 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 GAP87790.1 - 3.3e-34 117.3 0.2 8.1e-12 45.6 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP87790.1 - 3.6e-23 81.6 5.2 1.9e-06 28.3 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 GAP87790.1 - 1.5e-22 79.0 0.1 2.9e-05 24.3 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GAP87790.1 - 1e-21 76.7 0.1 7.4e-07 29.3 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP87790.1 - 7.2e-21 72.1 0.4 8.1e-07 28.9 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat SRPRB PF09439.10 GAP87791.1 - 3.3e-25 88.6 0.0 2.7e-15 56.3 0.0 2.9 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 GAP87791.1 - 0.0096 16.3 0.6 0.015 15.7 0.6 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 GAP87791.1 - 0.014 15.4 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 GAP87791.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 GAP87791.1 - 0.027 13.9 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAP87791.1 - 0.039 13.5 0.0 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAP87791.1 - 0.093 12.6 0.1 0.54 10.1 0.2 2.2 2 1 0 2 2 2 0 RsgA GTPase cobW PF02492.19 GAP87791.1 - 0.16 11.6 0.1 4.8 6.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PALP PF00291.25 GAP87792.1 - 7.5e-64 216.0 0.2 9.5e-64 215.6 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 GAP87792.1 - 1.4e-12 47.8 0.0 1.1e-07 32.1 0.0 2.9 2 0 0 2 2 2 2 CBS domain CorA PF01544.18 GAP87794.1 - 1.5e-09 37.6 0.0 2.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MARVEL PF01284.23 GAP87795.1 - 3.8e-08 33.5 18.7 3.4e-07 30.4 18.7 2.0 1 1 0 1 1 1 1 Membrane-associating domain Rep_2 PF01719.17 GAP87796.1 - 1.9 8.3 6.2 4.8 6.9 6.1 1.8 1 1 0 1 1 1 0 Plasmid replication protein DUF3744 PF12558.8 GAP87796.1 - 4.2 8.2 10.1 27 5.6 4.2 3.2 1 1 1 2 2 2 0 ATP-binding cassette cobalt transporter BTB PF00651.31 GAP87798.1 - 0.00052 20.2 0.0 0.0019 18.4 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain PAP2_3 PF14378.6 GAP87799.1 - 1e-25 90.6 18.3 7.4e-19 68.2 3.0 3.0 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 GAP87799.1 - 0.00055 19.7 0.1 0.00055 19.7 0.1 2.5 2 1 0 2 2 2 1 PAP2 superfamily EptA_B_N PF08019.12 GAP87799.1 - 0.031 14.2 2.2 0.55 10.1 0.0 2.7 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB PAP2_C PF14360.6 GAP87799.1 - 0.07 13.7 0.4 0.07 13.7 0.4 3.1 4 0 0 4 4 4 0 PAP2 superfamily C-terminal Glyco_hydro_28 PF00295.17 GAP87800.1 - 2.3e-90 303.0 12.5 2.6e-90 302.8 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 GAP87800.1 - 0.0012 18.7 18.5 0.052 13.4 0.3 2.6 2 2 0 2 2 2 2 Right handed beta helix region HET PF06985.11 GAP87801.1 - 8.8e-20 71.6 0.0 1.9e-19 70.5 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-MYND PF01753.18 GAP87801.1 - 0.025 14.7 0.5 0.074 13.2 0.1 2.0 2 0 0 2 2 2 0 MYND finger DUF1771 PF08590.10 GAP87802.1 - 3.1e-18 65.9 10.2 5.3e-18 65.1 10.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 GAP87802.1 - 1.8e-12 47.4 0.6 5e-12 46.0 0.6 1.8 1 0 0 1 1 1 1 Smr domain FTHFS PF01268.19 GAP87802.1 - 0.01 14.0 0.0 0.011 13.9 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase HJURP_C PF12347.8 GAP87802.1 - 0.037 14.1 1.4 0.097 12.7 0.3 2.2 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat CENP-Q PF13094.6 GAP87802.1 - 1.7 8.8 8.9 4.1 7.6 8.9 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit G-alpha PF00503.20 GAP87803.1 - 4.2e-124 414.3 1.5 4.9e-124 414.1 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 GAP87803.1 - 3.8e-15 55.8 2.0 2.6e-10 40.0 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 GAP87803.1 - 8.6e-05 22.3 0.0 0.00036 20.3 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 GAP87803.1 - 0.0031 16.9 3.5 0.11 11.8 0.1 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 GAP87803.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 GAP87803.1 - 0.025 14.8 0.2 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 GAP87803.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 GAP87803.1 - 0.13 11.8 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAP87803.1 - 0.13 12.3 0.1 8.4 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 GAP87803.1 - 0.13 11.5 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family adh_short PF00106.25 GAP87804.1 - 2.5e-30 105.4 0.0 3.2e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87804.1 - 1.8e-20 73.5 0.0 2.4e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87804.1 - 1.7e-10 41.1 0.0 3.2e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAP87804.1 - 0.00029 20.2 0.0 0.00047 19.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CoA_binding_2 PF13380.6 GAP87804.1 - 0.0076 16.7 0.2 0.025 15.1 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain 3HCDH_N PF02737.18 GAP87804.1 - 0.0084 16.0 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAP87804.1 - 0.014 16.0 0.0 0.19 12.3 0.1 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GAP87804.1 - 0.015 14.7 0.0 0.034 13.5 0.1 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 GAP87804.1 - 0.042 13.3 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAP87804.1 - 0.053 13.6 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 GAP87804.1 - 0.081 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.6 GAP87804.1 - 0.086 12.7 0.1 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAP87804.1 - 0.11 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sas10 PF09368.10 GAP87805.1 - 2.3e-26 92.0 5.7 2.3e-26 92.0 5.7 2.8 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 GAP87805.1 - 1.9e-08 34.8 0.0 8.5e-08 32.7 0.0 2.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Glyco_hydro_16 PF00722.21 GAP87806.1 - 6.2e-14 51.9 0.0 9.8e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.18 GAP87807.1 - 6.8e-14 51.5 2.4 1.1e-13 50.9 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 GAP87807.1 - 2.9e-08 33.8 11.3 1.1e-05 25.7 5.8 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAP87807.1 - 0.0055 17.1 13.6 0.29 11.7 4.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP87807.1 - 0.0064 17.2 12.2 0.72 10.9 1.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 GAP87807.1 - 0.0064 17.2 0.4 2.2 9.0 0.0 2.8 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats ALG11_N PF15924.5 GAP87807.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 ALG11 mannosyltransferase N-terminus zf-C2H2_jaz PF12171.8 GAP87807.1 - 0.74 10.2 2.8 1.9 8.8 2.8 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding HET PF06985.11 GAP87808.1 - 0.0019 18.6 0.1 0.004 17.5 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RasGEF PF00617.19 GAP87809.1 - 5.1e-60 202.7 0.1 9.3e-60 201.8 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAP87809.1 - 8.2e-30 103.1 0.2 1.9e-29 102.0 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 GAP87809.1 - 1.5e-15 56.5 0.1 3.6e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAP87809.1 - 7.6e-14 51.3 0.1 1.6e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAP87809.1 - 2.2e-13 49.7 0.1 5.3e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 GAP87809.1 - 0.0015 18.6 0.7 0.003 17.6 0.0 1.9 2 0 0 2 2 2 1 WW domain Glyco_hydro_18 PF00704.28 GAP87811.1 - 1.7e-11 44.4 0.0 4.3e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SH3_1 PF00018.28 GAP87812.1 - 3e-05 23.5 0.0 7.4e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAP87812.1 - 0.025 14.4 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain Glyoxalase PF00903.25 GAP87813.1 - 0.0023 18.1 0.0 0.0026 18.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Hva1_TUDOR PF11160.8 GAP87814.1 - 8.4e-19 67.5 0.3 9.6e-19 67.3 0.3 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Fungal_trans PF04082.18 GAP87815.1 - 8.6e-26 90.5 1.1 1.2e-25 90.0 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP87815.1 - 2.7e-07 30.6 11.8 4.6e-07 29.8 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3961 PF13106.6 GAP87815.1 - 0.041 13.5 0.5 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3961) Sugarporin_N PF11471.8 GAP87815.1 - 0.14 12.2 0.3 0.43 10.6 0.3 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Cyclin_C PF02984.19 GAP87815.1 - 0.17 11.9 0.2 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain MFS_1 PF07690.16 GAP87816.1 - 4.6e-53 180.4 43.6 5.5e-49 167.0 45.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAP87816.1 - 7.6e-15 54.3 19.2 1.1e-14 53.8 19.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 GAP87816.1 - 0.72 8.1 15.1 0.048 11.9 1.3 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2530 PF10745.9 GAP87816.1 - 7.3 6.9 10.3 0.99 9.7 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) DUF3716 PF12511.8 GAP87817.1 - 5.5e-17 61.6 8.4 1.1e-16 60.6 8.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) SR-25 PF10500.9 GAP87817.1 - 0.00025 20.8 10.6 0.00044 19.9 10.6 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RskA PF10099.9 GAP87817.1 - 0.0033 17.7 17.7 0.0033 17.7 17.7 2.2 2 0 0 2 2 2 1 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 GAP87817.1 - 0.0034 16.5 32.5 0.0046 16.1 32.5 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Lin-8 PF03353.15 GAP87817.1 - 0.0037 16.9 25.5 0.0055 16.3 25.5 1.4 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist DUF4770 PF15994.5 GAP87817.1 - 0.0081 16.4 3.5 0.0081 16.4 3.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4770) Presenilin PF01080.17 GAP87817.1 - 0.03 13.1 26.1 0.043 12.6 26.1 1.3 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 GAP87817.1 - 0.057 11.7 39.5 0.08 11.2 39.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.9 GAP87817.1 - 0.064 11.8 18.1 0.084 11.4 18.1 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 GAP87817.1 - 0.096 9.8 24.8 0.12 9.4 24.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Dapper PF15268.6 GAP87817.1 - 0.13 11.1 26.1 0.17 10.7 26.1 1.1 1 0 0 1 1 1 0 Dapper Chorion_2 PF03964.15 GAP87817.1 - 0.44 11.4 22.8 1.2 10.0 22.8 1.7 1 0 0 1 1 1 0 Chorion family 2 Asp-B-Hydro_N PF05279.11 GAP87817.1 - 0.49 10.4 21.2 0.84 9.7 21.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CbiD PF01888.17 GAP87817.1 - 0.5 9.6 3.5 0.91 8.8 3.5 1.3 1 0 0 1 1 1 0 CbiD SARAF PF06682.12 GAP87817.1 - 0.66 9.6 22.0 1.2 8.8 22.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF572 PF04502.13 GAP87817.1 - 0.78 9.3 22.5 1.2 8.7 22.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Membralin PF09746.9 GAP87817.1 - 0.95 8.4 11.4 1.6 7.7 11.4 1.4 1 0 0 1 1 1 0 Tumour-associated protein DUF4045 PF13254.6 GAP87817.1 - 0.98 9.0 21.9 1.5 8.4 21.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) LAP1C PF05609.12 GAP87817.1 - 1.2 8.1 31.6 1.7 7.6 31.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_S64 PF08192.11 GAP87817.1 - 1.8 7.0 18.8 2.8 6.3 18.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Nop53 PF07767.11 GAP87817.1 - 1.8 7.9 31.5 3.2 7.0 31.5 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PRP1_N PF06424.12 GAP87817.1 - 1.8 8.9 23.1 3.5 8.0 23.1 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Ndc1_Nup PF09531.10 GAP87817.1 - 2 7.0 19.9 2.5 6.7 19.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM60A PF15396.6 GAP87817.1 - 2.9 7.9 21.4 6.7 6.7 21.4 1.6 1 0 0 1 1 1 0 Protein Family FAM60A ALMT PF11744.8 GAP87817.1 - 3.1 6.5 25.7 4.3 6.1 24.9 1.5 2 0 0 2 2 2 0 Aluminium activated malate transporter PI3K_1B_p101 PF10486.9 GAP87817.1 - 3.2 5.4 19.4 4.4 4.9 19.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2828 PF11443.8 GAP87817.1 - 3.6 5.6 25.6 5.4 5.0 25.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CDC45 PF02724.14 GAP87817.1 - 6.9 4.8 27.9 10 4.3 27.9 1.1 1 0 0 1 1 1 0 CDC45-like protein GPCR_chapero_1 PF11904.8 GAP87817.1 - 9.3 5.6 15.1 14 5.0 15.1 1.2 1 0 0 1 1 1 0 GPCR-chaperone WD40 PF00400.32 GAP87818.1 - 1.2e-10 41.7 0.8 7.5e-05 23.4 0.1 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP87818.1 - 0.0013 19.0 0.0 1.4 9.3 0.0 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HNH_2 PF13391.6 GAP87820.1 - 0.0011 19.1 0.0 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease DUF1264 PF06884.11 GAP87821.1 - 6.5e-53 178.8 0.0 8.2e-53 178.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) p450 PF00067.22 GAP87822.1 - 1.5e-47 162.4 0.0 2e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAP87823.1 - 1.4e-21 76.8 0.0 1.5e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 GAP87824.1 - 5.3e-15 55.4 0.0 4.8e-10 39.2 0.0 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87824.1 - 4.9e-09 36.1 0.0 0.0015 18.1 0.0 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87824.1 - 2e-05 24.6 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP87824.1 - 0.0077 15.7 0.0 0.03 13.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 GAP87824.1 - 0.021 14.2 0.0 0.087 12.2 0.0 2.0 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme LMBR1 PF04791.16 GAP87825.1 - 0.27 10.1 2.3 0.38 9.6 2.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0242 PF06785.11 GAP87825.1 - 0.34 11.0 11.6 0.94 9.6 11.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CREPT PF16566.5 GAP87825.1 - 0.4 10.8 9.9 0.6 10.3 8.6 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3877 PF12993.7 GAP87826.1 - 0.031 14.2 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF812 PF05667.11 GAP87826.1 - 0.24 10.2 4.5 0.35 9.7 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Atg14 PF10186.9 GAP87826.1 - 1.5 7.8 3.9 1.2 8.2 0.3 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 THOC7 PF05615.13 GAP87826.1 - 1.8 8.9 12.3 0.065 13.5 4.1 2.5 2 1 0 2 2 2 0 Tho complex subunit 7 She9_MDM33 PF05546.11 GAP87826.1 - 2.8 7.7 6.8 4 7.2 0.7 2.3 2 0 0 2 2 2 0 She9 / Mdm33 family Sugar_tr PF00083.24 GAP87827.1 - 9.4e-94 314.8 25.0 1.1e-93 314.6 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP87827.1 - 8.9e-35 120.2 23.3 8.9e-35 120.2 23.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.25 GAP87828.1 - 4.2e-07 29.6 0.0 8.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 GAP87828.1 - 1.5e-06 28.0 0.5 4e-06 26.6 0.1 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 GAP87828.1 - 0.0013 18.1 0.2 0.0022 17.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP87828.1 - 0.0018 18.3 0.2 0.0029 17.6 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAP87828.1 - 0.015 14.9 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family NdhN PF11909.8 GAP87828.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N ROKNT PF08067.11 GAP87828.1 - 0.23 11.8 2.3 0.49 10.7 2.3 1.5 1 0 0 1 1 1 0 ROKNT (NUC014) domain CENP-Q PF13094.6 GAP87829.1 - 0.096 12.9 6.6 0.18 12.0 6.6 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.6 GAP87829.1 - 0.86 8.9 4.3 1.1 8.6 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_hydro_92 PF07971.12 GAP87830.1 - 3.4e-138 461.5 0.1 4e-138 461.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAP87830.1 - 4.1e-48 164.4 1.4 5.9e-48 163.8 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain UPF0126 PF03458.13 GAP87831.1 - 1.9 8.5 9.8 0.33 10.9 2.2 2.8 2 1 0 2 2 2 0 UPF0126 domain UQ_con PF00179.26 GAP87832.1 - 2.1e-05 24.2 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3486 PF11985.8 GAP87833.1 - 0.0074 16.7 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3486) Glyco_hydro_72 PF03198.14 GAP87834.1 - 1.5e-98 329.9 0.2 2.6e-98 329.2 0.2 1.3 2 0 0 2 2 2 1 Glucanosyltransferase Rubella_E2 PF05749.11 GAP87834.1 - 0.005 16.3 2.5 0.0074 15.8 2.5 1.3 1 0 0 1 1 1 1 Rubella membrane glycoprotein E2 Cellulase PF00150.18 GAP87834.1 - 0.009 15.5 0.1 0.023 14.1 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sof1 PF04158.14 GAP87835.1 - 1.2e-31 108.8 16.8 2.6e-31 107.7 16.8 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 GAP87835.1 - 9.4e-30 102.2 11.2 3.5e-09 37.1 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP87835.1 - 3.4e-11 43.3 0.1 0.05 13.9 0.0 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 GAP87835.1 - 6.7e-05 22.9 0.0 29 4.7 0.0 5.0 3 2 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 GAP87835.1 - 0.00091 19.6 0.1 1.2 9.7 0.0 3.6 4 0 0 4 4 4 1 PQQ-like domain Frtz PF11768.8 GAP87835.1 - 0.034 12.5 0.0 2.1 6.6 0.0 2.8 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz RICH PF05062.12 GAP87835.1 - 0.039 14.3 3.6 0.084 13.2 3.6 1.5 1 0 0 1 1 1 0 RICH domain adh_short PF00106.25 GAP87836.1 - 5.3e-39 133.7 0.1 6.7e-39 133.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87836.1 - 1.3e-30 106.7 0.0 1.9e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87836.1 - 5.1e-10 39.6 4.4 3.2e-09 37.0 4.5 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP87836.1 - 0.16 11.4 0.1 0.86 9.0 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 GAP87837.1 - 4.8e-07 29.4 0.0 0.028 13.8 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87837.1 - 0.0036 16.6 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RPN6_N PF18055.1 GAP87838.1 - 2.9e-47 159.8 0.8 1.6e-46 157.4 0.3 2.5 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 GAP87838.1 - 3.2e-20 72.6 0.6 9.8e-20 71.0 0.1 2.1 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 GAP87838.1 - 2.6e-11 43.0 0.9 5.7e-11 41.9 0.9 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 GAP87838.1 - 5.9e-05 22.6 1.3 5.9e-05 22.6 1.3 2.2 2 1 0 2 2 2 1 MalT-like TPR region DDRGK PF09756.9 GAP87838.1 - 0.0025 17.4 0.2 0.0044 16.6 0.2 1.3 1 0 0 1 1 1 1 DDRGK domain DUF4456 PF14644.6 GAP87838.1 - 0.017 14.8 1.6 3.1 7.4 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) TPR_12 PF13424.6 GAP87838.1 - 0.02 15.2 15.2 0.025 14.9 2.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 GAP87838.1 - 0.045 13.7 0.1 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DUF4398 PF14346.6 GAP87838.1 - 0.8 10.4 6.1 0.57 10.8 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) TPR_11 PF13414.6 GAP87838.1 - 0.89 9.3 4.0 46 3.8 0.1 3.6 3 0 0 3 3 3 0 TPR repeat TPR_21 PF09976.9 GAP87838.1 - 2.5 7.7 11.5 0.22 11.2 1.2 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain DSBA PF01323.20 GAP87841.1 - 2e-09 37.5 0.0 2.2e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain HypD PF01924.16 GAP87841.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family DSBA PF01323.20 GAP87842.1 - 1.5e-13 51.0 2.3 3.6e-13 49.7 1.6 1.7 2 0 0 2 2 2 1 DSBA-like thioredoxin domain Sds3 PF08598.11 GAP87843.1 - 6.5e-20 72.1 18.6 1.2e-19 71.2 18.6 1.5 1 1 0 1 1 1 1 Sds3-like HET PF06985.11 GAP87844.1 - 3.9e-28 98.6 0.3 6.4e-28 97.9 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GATase PF00117.28 GAP87845.1 - 9.4e-12 45.1 0.0 1.2e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I MFS_1 PF07690.16 GAP87846.1 - 2.2e-34 118.9 37.7 2.2e-34 118.9 37.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 GAP87846.1 - 0.14 10.4 9.0 0.64 8.2 9.0 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DAO PF01266.24 GAP87847.1 - 1.4e-21 77.5 0.1 2.5e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Formyl_trans_N PF00551.19 GAP87847.1 - 1.1e-13 51.3 0.0 2.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase Pyr_redox PF00070.27 GAP87847.1 - 7.5e-06 26.4 0.0 0.058 14.0 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAP87847.1 - 6.2e-05 22.4 0.0 0.00048 19.5 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP87847.1 - 0.0002 20.7 0.0 0.57 9.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP87847.1 - 0.0021 16.8 0.0 1.5 7.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 GAP87847.1 - 0.003 17.8 0.0 0.0073 16.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 GAP87847.1 - 0.0083 15.5 0.0 0.031 13.6 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 GAP87847.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.24 GAP87848.1 - 3.2e-110 369.1 12.2 3.9e-110 368.8 12.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP87848.1 - 2.5e-29 102.3 22.6 2.5e-29 102.3 22.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP87848.1 - 0.00058 18.4 3.0 0.001 17.6 3.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAP87850.1 - 4.4e-42 144.3 40.4 4.4e-42 144.3 40.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP87850.1 - 1.9e-11 43.5 11.8 1.9e-11 43.5 11.8 2.3 2 1 0 3 3 3 1 Sugar (and other) transporter zinc_ribbon_2 PF13240.6 GAP87851.1 - 0.015 15.0 0.1 0.015 15.0 0.1 2.3 3 0 0 3 3 3 0 zinc-ribbon domain GFA PF04828.14 GAP87851.1 - 0.017 15.4 4.1 0.04 14.3 4.1 1.6 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.6 GAP87851.1 - 0.021 15.2 3.7 0.12 12.8 0.2 2.4 3 0 0 3 3 3 0 Cysteine-rich CWC Chorismate_bind PF00425.18 GAP87852.1 - 2.5e-92 309.1 0.0 1.4e-90 303.4 0.0 2.1 2 0 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 GAP87852.1 - 1.6e-24 86.8 0.0 3.8e-20 72.5 0.0 3.5 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region NuiA PF07924.11 GAP87853.1 - 0.00024 21.5 0.0 0.0033 17.8 0.0 2.2 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein Ribosomal_L3 PF00297.22 GAP87854.1 - 6.7e-158 525.5 10.2 7.6e-158 525.3 10.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.28 GAP87855.1 - 1.5e-53 176.5 31.2 4.9e-08 32.5 0.1 10.8 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 GAP87855.1 - 1.9e-48 158.7 21.2 3.3e-06 26.8 0.0 10.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 GAP87855.1 - 6.8e-41 135.1 21.0 1e-06 28.4 0.0 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.6 GAP87855.1 - 8.7e-28 96.7 8.0 2.4e-06 28.1 0.1 6.3 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 GAP87855.1 - 2.1e-27 93.5 18.9 0.0017 18.6 0.1 10.2 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAP87855.1 - 9.7e-27 93.3 16.7 9.5e-05 22.8 0.1 6.9 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.6 GAP87855.1 - 9.8e-27 91.4 12.5 0.00034 21.2 0.0 8.9 2 2 7 9 9 9 8 Tetratricopeptide repeat TPR_6 PF13174.6 GAP87855.1 - 1.4e-22 78.7 15.2 0.0031 18.0 0.0 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAP87855.1 - 1.7e-22 78.8 31.4 3.1e-06 26.8 0.2 9.3 5 2 4 9 9 9 5 TPR repeat TPR_12 PF13424.6 GAP87855.1 - 1.8e-21 76.2 23.3 3.5e-05 24.0 0.8 7.5 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAP87855.1 - 3.3e-19 67.4 15.1 0.0085 16.1 0.1 9.6 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 GAP87855.1 - 1.6e-15 57.0 12.7 0.0008 19.5 0.2 6.7 2 2 7 9 9 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP87855.1 - 2.5e-15 56.4 8.5 1.8e-08 34.5 1.5 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 GAP87855.1 - 2.9e-12 46.4 7.8 0.0019 17.5 0.1 5.4 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_21 PF09976.9 GAP87855.1 - 1.5e-07 31.3 6.8 0.13 11.9 0.0 5.1 3 2 1 5 5 5 2 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 GAP87855.1 - 0.00031 21.0 3.8 0.69 10.3 0.0 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat DUF2225 PF09986.9 GAP87855.1 - 0.012 15.4 2.6 1.6 8.4 0.0 3.3 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.6 GAP87855.1 - 1.3 8.4 15.0 16 4.8 0.3 4.9 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 GAP87855.1 - 1.4 8.9 23.3 18 5.4 0.0 7.8 9 0 0 9 9 9 0 Tetratricopeptide repeat BTAD PF03704.17 GAP87855.1 - 3.8 7.9 16.7 9 6.7 0.1 4.3 4 1 0 4 4 4 0 Bacterial transcriptional activator domain MIT PF04212.18 GAP87855.1 - 8.4 6.6 21.6 13 6.0 1.8 6.7 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain DUF1751 PF08551.10 GAP87856.1 - 4e-27 94.7 4.1 7.3e-27 93.8 4.1 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 GAP87856.1 - 0.04 13.9 5.3 0.09 12.8 5.3 1.6 1 1 0 1 1 1 0 Rhomboid family WD40 PF00400.32 GAP87857.1 - 2.7e-13 50.2 6.9 0.00033 21.4 0.0 6.8 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP87857.1 - 2.1e-09 37.6 0.1 0.0071 16.6 0.0 5.3 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 GAP87857.1 - 3.1e-06 26.9 0.1 7.4e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 GAP87857.1 - 7.9e-05 22.6 0.0 1.4 8.8 0.0 3.4 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Alpha-L-AF_C PF06964.12 GAP87858.1 - 1.4e-29 103.4 0.1 2e-29 102.8 0.1 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_79n PF03662.14 GAP87858.1 - 0.14 11.1 0.0 0.29 10.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain Reprolysin_5 PF13688.6 GAP87861.1 - 2.8e-57 194.0 6.1 2.8e-57 194.0 6.1 3.2 3 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 GAP87861.1 - 7.6e-50 169.5 1.8 1.7e-49 168.3 1.8 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 GAP87861.1 - 2.4e-47 161.2 2.1 5.4e-47 160.1 2.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 GAP87861.1 - 4.5e-17 62.6 34.3 4.5e-17 62.6 34.3 4.8 4 1 1 5 5 5 1 Disintegrin Reprolysin_3 PF13582.6 GAP87861.1 - 3.7e-11 43.6 0.0 1.6e-10 41.6 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 GAP87861.1 - 0.00068 19.6 8.3 0.00068 19.6 8.3 3.5 1 1 1 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 GAP87861.1 - 0.0013 19.0 0.1 0.0025 18.0 0.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide AMP-binding PF00501.28 GAP87862.1 - 2.5e-82 276.8 0.0 3.1e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP87862.1 - 6.6e-24 84.7 0.7 4.3e-23 82.1 0.8 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 GAP87862.1 - 4.7e-19 68.1 0.6 1.2e-18 66.7 0.3 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DNA_pol3_delta2 PF13177.6 GAP87863.1 - 7.8e-11 42.0 0.0 1.6e-10 41.0 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 GAP87863.1 - 1.8e-06 28.4 0.1 4.4e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAP87863.1 - 5.7e-06 26.7 0.2 6.5e-05 23.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAP87863.1 - 4.9e-05 23.8 0.4 0.0029 18.0 0.3 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 GAP87863.1 - 0.0003 20.6 1.0 0.00079 19.2 0.4 1.9 2 1 0 2 2 2 1 AAA domain Rep_fac_C PF08542.11 GAP87863.1 - 0.00066 20.0 0.3 0.002 18.5 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain ABC_tran PF00005.27 GAP87863.1 - 0.017 15.7 0.0 0.04 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Resolvase PF00239.21 GAP87863.1 - 0.026 14.6 0.1 1.2 9.3 0.3 2.5 2 1 0 2 2 2 0 Resolvase, N terminal domain Rad17 PF03215.15 GAP87863.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain T4SS-DNA_transf PF02534.14 GAP87863.1 - 0.063 12.1 0.1 0.18 10.6 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Prenyltransf PF01255.19 GAP87863.1 - 0.13 11.8 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Aminotran_1_2 PF00155.21 GAP87864.1 - 1.4e-33 116.5 0.0 1.7e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_1 PF00076.22 GAP87865.1 - 7.3e-16 57.8 0.0 1.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 GAP87865.1 - 0.0016 19.0 2.9 0.0016 19.0 2.9 2.8 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 GAP87865.1 - 0.0025 17.6 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif DFRP_C PF16543.5 GAP87866.1 - 8.5e-27 93.5 8.3 8.5e-27 93.5 8.3 3.5 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 GAP87866.1 - 7.6e-07 28.9 8.4 1.5e-06 28.0 0.4 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAP87866.1 - 6.3e-06 25.9 7.7 0.0013 18.5 1.7 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 GAP87866.1 - 7.1e-06 26.7 2.6 7.1e-06 26.7 2.6 3.6 2 2 2 4 4 4 2 Torus domain zf_CCCH_4 PF18345.1 GAP87866.1 - 7.6e-05 22.6 6.4 7.6e-05 22.6 6.4 3.2 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_3 PF15663.5 GAP87866.1 - 0.00025 21.3 2.2 0.025 14.8 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 GAP87866.1 - 0.36 11.4 14.4 0.23 12.0 3.7 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger LptF_LptG PF03739.14 GAP87866.1 - 3 6.6 4.2 4.7 6.0 0.8 2.0 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Pkinase PF00069.25 GAP87868.1 - 3.1e-75 253.0 1.0 2.4e-74 250.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87868.1 - 9.4e-30 103.7 3.6 7.9e-22 77.8 0.0 2.6 3 0 0 3 3 2 2 Protein tyrosine kinase TFIIA PF03153.13 GAP87868.1 - 9.8e-06 25.8 12.1 1.5e-05 25.2 12.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Kinase-like PF14531.6 GAP87868.1 - 1.1e-05 24.9 0.0 1.5 8.1 0.0 3.3 3 0 0 3 3 3 2 Kinase-like Spt20 PF12090.8 GAP87868.1 - 0.00049 19.8 20.1 0.0008 19.1 20.1 1.3 1 0 0 1 1 1 1 Spt20 family Pkinase_fungal PF17667.1 GAP87868.1 - 0.0019 17.0 1.8 0.054 12.3 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Suf PF05843.14 GAP87868.1 - 0.42 10.6 13.8 0.7 9.8 13.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EPL1 PF10513.9 GAP87868.1 - 0.67 10.3 8.3 1.3 9.3 8.3 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like Activator_LAG-3 PF11498.8 GAP87868.1 - 0.93 8.4 29.9 1.7 7.5 29.9 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TERB2 PF15101.6 GAP87868.1 - 1.9 8.5 10.5 3.3 7.7 10.5 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 GAP87868.1 - 2.1 7.0 7.0 3.1 6.5 7.0 1.1 1 0 0 1 1 1 0 Presenilin SprA-related PF12118.8 GAP87868.1 - 3.1 6.9 16.0 5.3 6.1 16.0 1.3 1 0 0 1 1 1 0 SprA-related family CPSF100_C PF13299.6 GAP87868.1 - 3.7 7.7 6.1 8.1 6.6 6.1 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4834 PF16118.5 GAP87868.1 - 4.1 8.4 10.3 9.9 7.2 10.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Hamartin PF04388.12 GAP87868.1 - 6.4 5.3 20.1 8 5.0 20.1 1.1 1 0 0 1 1 1 0 Hamartin protein DivIC PF04977.15 GAP87868.1 - 7.5 6.4 15.6 16 5.3 15.6 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF3464 PF11947.8 GAP87868.1 - 8.9 6.0 7.5 17 5.2 7.5 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CENP-B_dimeris PF09026.10 GAP87869.1 - 0.0071 16.7 5.5 0.0071 16.7 5.5 2.4 2 0 0 2 2 2 1 Centromere protein B dimerisation domain FAM176 PF14851.6 GAP87869.1 - 0.19 11.4 1.3 0.35 10.5 0.2 2.0 2 0 0 2 2 2 0 FAM176 family Sporozoite_P67 PF05642.11 GAP87869.1 - 0.24 9.5 0.5 0.36 8.8 0.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Thi4 PF01946.17 GAP87870.1 - 2.5e-87 292.0 0.1 6e-87 290.8 0.1 1.6 1 1 0 1 1 1 1 Thi4 family DAO PF01266.24 GAP87870.1 - 4.8e-07 29.7 7.2 2.2e-06 27.5 2.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP87870.1 - 1.4e-05 25.3 0.3 3.8e-05 23.8 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAP87870.1 - 1.9e-05 23.9 0.1 2.6e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAP87870.1 - 7.2e-05 22.2 0.0 8.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAP87870.1 - 0.00026 20.5 0.1 0.00039 19.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP87870.1 - 0.00057 19.1 1.2 0.00057 19.1 1.2 2.4 2 1 1 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 GAP87870.1 - 0.0008 19.4 0.1 0.0018 18.3 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 GAP87870.1 - 0.012 14.9 0.2 0.025 13.8 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 GAP87870.1 - 0.021 13.6 0.9 0.037 12.7 0.5 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAP87870.1 - 0.045 13.0 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 GAP87870.1 - 0.097 11.2 0.1 1.1 7.7 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 GAP87870.1 - 0.11 11.6 0.3 0.19 10.8 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAP87870.1 - 0.12 11.1 0.3 0.18 10.6 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Cutinase PF01083.22 GAP87871.1 - 4.4e-40 137.5 2.1 5.5e-40 137.2 2.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAP87871.1 - 0.00051 19.7 0.8 0.0012 18.5 0.6 1.7 1 1 1 2 2 2 1 PE-PPE domain VirJ PF06057.11 GAP87871.1 - 0.044 13.7 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) NiFe_hyd_3_EhaA PF17367.2 GAP87872.1 - 0.099 12.8 0.9 0.13 12.4 0.9 1.1 1 0 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A Kinesin PF00225.23 GAP87874.1 - 1.9e-91 306.4 0.0 1.9e-91 306.4 0.0 3.1 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAP87874.1 - 1.7e-18 67.0 0.1 3.9e-14 52.8 0.0 4.1 2 1 1 3 3 3 2 Microtubule binding AAA_24 PF13479.6 GAP87874.1 - 0.0032 17.2 1.7 0.79 9.4 0.2 3.5 2 0 0 2 2 2 2 AAA domain ERCC4 PF02732.15 GAP87875.1 - 2.8e-24 86.1 0.0 5.5e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain PA26 PF04636.13 GAP87875.1 - 0.27 10.1 1.9 0.42 9.5 1.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4246 PF14033.6 GAP87876.1 - 1.2e-150 502.5 0.0 2.2e-150 501.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 GAP87876.1 - 0.049 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Ank_5 PF13857.6 GAP87879.1 - 1.2e-08 35.0 0.2 0.0025 18.1 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP87879.1 - 9.2e-08 31.8 0.0 4 8.3 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 GAP87879.1 - 8.1e-06 26.3 0.0 0.00095 19.7 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP87879.1 - 3.3e-05 24.4 0.0 0.21 12.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAP87879.1 - 0.0011 19.3 0.0 2 9.0 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeat Glyco_hydro_61 PF03443.14 GAP87880.1 - 1.2e-54 185.4 0.1 1.3e-54 185.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PLA2_B PF01735.18 GAP87880.1 - 0.0061 15.0 0.1 0.01 14.2 0.1 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain CSD PF00313.22 GAP87880.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Peptidase_S8 PF00082.22 GAP87881.1 - 6.5e-15 55.2 0.0 1.3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 GAP87881.1 - 0.0034 17.9 0.0 3.1 8.4 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 GAP87881.1 - 0.015 15.7 0.0 0.096 13.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat RRS1 PF04939.12 GAP87881.1 - 0.032 14.1 0.2 0.078 12.8 0.2 1.6 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) Ank_2 PF12796.7 GAP87883.1 - 1.2e-64 214.8 0.1 7.5e-12 45.7 0.3 10.7 4 3 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP87883.1 - 2.6e-49 165.0 6.5 1e-05 26.0 0.0 12.2 5 2 7 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP87883.1 - 1.1e-37 123.7 14.2 0.022 15.3 0.0 17.5 19 0 0 19 19 19 8 Ankyrin repeat Ank_5 PF13857.6 GAP87883.1 - 1.8e-30 104.6 12.0 3.5e-08 33.5 0.1 11.4 8 3 4 12 12 12 7 Ankyrin repeats (many copies) Ank PF00023.30 GAP87883.1 - 4e-30 102.9 14.7 0.001 19.4 0.0 14.2 16 0 0 16 16 16 6 Ankyrin repeat Pkinase PF00069.25 GAP87883.1 - 6.5e-09 35.5 0.0 1.6e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain DUF3447 PF11929.8 GAP87883.1 - 0.014 15.4 0.0 13 5.8 0.0 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF3447) Pkinase_Tyr PF07714.17 GAP87883.1 - 0.11 11.8 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase LuxT_C PF18285.1 GAP87883.1 - 0.22 12.1 0.3 7 7.3 0.1 3.3 3 0 0 3 3 3 0 Tetracycline repressor LuxT C-terminal domain Astro_capsid_p PF12226.8 GAP87883.1 - 5.7 6.0 6.7 9.5 5.3 6.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein COesterase PF00135.28 GAP87884.1 - 4.6e-72 243.5 0.0 1.1e-64 219.1 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP87884.1 - 1.9e-08 34.4 0.2 0.0037 17.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP87884.1 - 1.5 9.4 10.3 0.37 11.4 6.4 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family Exo_endo_phos PF03372.23 GAP87885.1 - 0.035 13.6 0.7 0.049 13.1 0.7 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Mur_ligase_C PF02875.21 GAP87885.1 - 0.093 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF3136 PF11334.8 GAP87887.1 - 0.08 12.7 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) RasGEF PF00617.19 GAP87888.1 - 6.4e-54 182.8 0.0 1.7e-53 181.4 0.0 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAP87888.1 - 3.2e-17 62.7 0.0 8.1e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 GAP87888.1 - 1.8e-06 27.7 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 GAP87888.1 - 6e-05 22.6 0.0 0.00014 21.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAP87888.1 - 0.014 15.0 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain MFS_1 PF07690.16 GAP87889.1 - 3.3e-15 55.9 37.6 1e-14 54.3 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 GAP87889.1 - 4.9e-11 42.6 9.7 4.9e-11 42.6 9.7 3.2 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 DUF3493 PF11998.8 GAP87889.1 - 0.0021 18.2 0.9 0.15 12.2 1.1 3.1 2 0 0 2 2 2 1 Low psii accumulation1 / Rep27 DUF5336 PF17270.2 GAP87889.1 - 0.38 10.4 5.8 0.63 9.7 1.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5336) Pectate_lyase PF03211.13 GAP87890.1 - 2.3e-80 269.0 5.5 2.6e-80 268.8 5.5 1.0 1 0 0 1 1 1 1 Pectate lyase F-box PF00646.33 GAP87893.1 - 0.095 12.6 0.1 0.34 10.9 0.1 1.9 1 0 0 1 1 1 0 F-box domain NUDIX PF00293.28 GAP87894.1 - 3.1e-12 46.7 0.0 4.1e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain HET PF06985.11 GAP87895.1 - 2.5e-11 44.1 0.1 5.5e-11 43.0 0.1 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) RelA_SpoT PF04607.17 GAP87896.1 - 2.3e-12 47.2 0.0 6.5e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins VirDNA-topo-I_N PF09266.10 GAP87896.1 - 0.11 12.6 0.3 1.8 8.8 0.0 2.7 3 0 0 3 3 3 0 Viral DNA topoisomerase I, N-terminal Dynein_light PF01221.18 GAP87896.1 - 0.12 12.7 0.3 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 Dynein light chain type 1 HET PF06985.11 GAP87897.1 - 1.8e-19 70.5 0.0 3e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 GAP87898.1 - 6.1e-22 78.2 0.0 1.2e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP87898.1 - 3.3e-16 59.3 0.0 5.3e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 GAP87898.1 - 0.0088 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pectate_lyase_3 PF12708.7 GAP87899.1 - 1.2e-56 192.0 20.7 6.3e-41 140.6 2.5 3.9 3 1 1 4 4 4 3 Pectate lyase superfamily protein Peptidase_S8 PF00082.22 GAP87899.1 - 6e-18 65.1 0.3 1.6e-17 63.7 0.3 1.7 1 0 0 1 1 1 1 Subtilase family DUF333 PF03891.15 GAP87900.1 - 0.077 13.2 0.2 2.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF333) adh_short PF00106.25 GAP87903.1 - 3.9e-12 46.0 0.0 5.9e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAP87903.1 - 1.4e-07 31.6 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP87903.1 - 4.7e-05 23.0 0.0 0.00014 21.4 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP87903.1 - 0.0032 17.4 0.1 0.005 16.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAP87903.1 - 0.012 15.0 0.0 0.038 13.4 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAP87903.1 - 0.035 13.2 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAP87903.1 - 0.13 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAP87904.1 - 1.6e-08 34.7 0.1 2e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAP87904.1 - 0.039 13.1 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein DapB_N PF01113.20 GAP87904.1 - 0.051 13.7 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 GAP87904.1 - 0.056 14.1 0.3 0.19 12.5 0.1 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.24 GAP87904.1 - 0.059 13.8 0.1 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAP87904.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 GAP87904.1 - 0.11 11.9 0.1 0.18 11.2 0.0 1.6 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family AcetylCoA_hydro PF02550.15 GAP87907.1 - 4.9e-50 170.3 0.0 7.8e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 GAP87907.1 - 1.5e-40 138.6 0.0 2.4e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF1992 PF09350.10 GAP87908.1 - 2.7e-20 72.3 1.2 6.1e-20 71.1 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Pyridoxal_deC PF00282.19 GAP87910.1 - 2.3e-14 52.9 0.0 5.1e-06 25.5 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain HET PF06985.11 GAP87911.1 - 1.3e-10 41.8 5.4 5.8e-09 36.5 0.6 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NAD_binding_10 PF13460.6 GAP87912.1 - 5.9e-13 49.1 2.6 1.1e-12 48.3 2.6 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAP87912.1 - 3.9e-09 36.4 0.6 6.9e-09 35.6 0.6 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAP87912.1 - 0.00014 21.4 0.3 0.00024 20.6 0.3 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 GAP87912.1 - 0.0018 18.4 0.3 0.0032 17.6 0.3 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 GAP87912.1 - 0.0045 17.4 0.8 0.008 16.6 0.8 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 GAP87912.1 - 0.0048 17.7 0.2 0.026 15.4 0.2 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 GAP87912.1 - 0.18 12.4 1.4 0.38 11.4 1.4 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3433 PF11915.8 GAP87913.1 - 1.1e-22 80.2 11.1 1.9e-13 50.6 0.2 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF1664 PF07889.12 GAP87914.1 - 0.00041 20.4 18.3 0.059 13.4 4.4 3.5 1 1 3 4 4 4 4 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 GAP87914.1 - 0.032 14.3 12.7 0.38 10.8 3.8 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.11 GAP87914.1 - 0.056 12.3 19.1 0.087 11.7 19.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CLZ PF16526.5 GAP87914.1 - 0.063 13.6 22.0 2.6 8.5 0.4 4.7 3 2 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tropomyosin_1 PF12718.7 GAP87914.1 - 0.14 12.3 27.8 0.031 14.4 10.8 3.5 1 1 2 3 3 3 0 Tropomyosin like DUF4200 PF13863.6 GAP87914.1 - 0.42 11.0 25.3 1.1 9.7 0.6 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) TMPIT PF07851.13 GAP87914.1 - 0.43 9.8 12.3 1.2 8.3 2.9 2.3 2 0 0 2 2 2 0 TMPIT-like protein DUF16 PF01519.16 GAP87914.1 - 0.46 11.0 19.3 0.14 12.7 0.8 3.3 1 1 2 3 3 3 0 Protein of unknown function DUF16 TipAS PF07739.13 GAP87914.1 - 0.51 10.9 6.2 0.72 10.4 0.6 2.6 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Lectin_N PF03954.14 GAP87914.1 - 0.65 9.8 15.1 4.1 7.2 0.3 3.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain AAA_13 PF13166.6 GAP87914.1 - 0.98 8.0 20.2 3.6 6.1 20.4 1.8 1 1 0 1 1 1 0 AAA domain Fzo_mitofusin PF04799.13 GAP87914.1 - 1.5 8.3 16.8 0.42 10.2 6.3 3.1 1 1 2 3 3 3 0 fzo-like conserved region DUF4795 PF16043.5 GAP87914.1 - 1.5 8.4 19.9 3.3 7.3 6.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 GAP87914.1 - 2.7 8.2 15.8 1.9 8.7 3.8 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 GAP87914.1 - 8.9 6.6 16.5 2.9 8.2 0.4 4.9 3 2 2 5 5 5 0 Haemolysin XhlA WXG100 PF06013.12 GAP87914.1 - 9.7 6.5 10.3 19 5.5 0.0 4.0 2 1 2 4 4 4 0 Proteins of 100 residues with WXG Pectate_lyase PF03211.13 GAP87915.1 - 1.8e-83 279.1 9.5 2.3e-83 278.7 9.5 1.2 1 0 0 1 1 1 1 Pectate lyase MSP1_C PF07462.11 GAP87915.1 - 0.6 8.7 1.7 0.83 8.3 1.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PIGA PF08288.12 GAP87916.1 - 9.2e-44 148.0 3.1 4e-43 145.9 0.7 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 GAP87916.1 - 2.1e-28 99.0 0.0 3.2e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAP87916.1 - 8.4e-28 97.5 0.3 1.5e-27 96.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 GAP87916.1 - 1.9e-23 83.4 0.1 3.8e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 GAP87916.1 - 4.7e-13 49.9 0.0 9.2e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 GAP87916.1 - 6.9e-06 26.1 0.1 1.6e-05 25.0 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 GAP87916.1 - 3.2e-05 24.2 0.0 0.00012 22.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 GAP87916.1 - 0.1 12.2 0.1 0.37 10.5 0.0 1.9 1 1 1 2 2 2 0 Starch synthase catalytic domain DEAD PF00270.29 GAP87917.1 - 3.8e-33 114.7 0.0 2.9e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP87917.1 - 8.7e-23 80.8 0.0 2.4e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP87917.1 - 1.8e-05 24.8 0.0 4.5e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 GAP87917.1 - 0.0052 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain LPD15 PF18828.1 GAP87917.1 - 1.7 8.5 3.5 0.67 9.9 0.2 2.0 2 0 0 2 2 2 0 Large polyvalent-protein-associated domain 15 DUF3984 PF13136.6 GAP87918.1 - 8.3 5.7 10.9 13 5.1 10.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) KxDL PF10241.9 GAP87919.1 - 1.6e-30 105.2 1.0 2.3e-30 104.7 1.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.11 GAP87919.1 - 0.048 13.4 0.1 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism SNRNP27 PF08648.12 GAP87920.1 - 0.12 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins Cir_N PF10197.9 GAP87922.1 - 5.8e-07 29.6 5.3 5.8e-07 29.6 5.3 4.6 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_11 PF08241.12 GAP87923.1 - 2.2e-11 44.2 0.0 3.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP87923.1 - 6.2e-10 39.6 0.0 9.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP87923.1 - 5.1e-09 36.2 0.0 8.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP87923.1 - 3.8e-08 34.0 0.0 5.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 GAP87923.1 - 1.9e-07 30.9 0.0 2.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 GAP87923.1 - 5.5e-06 26.2 0.0 9.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAP87923.1 - 4.5e-05 23.0 0.0 7.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_16 PF10294.9 GAP87923.1 - 0.00017 21.4 0.0 0.00023 20.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 GAP87923.1 - 0.00092 19.0 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) NTP_transf_9 PF04248.12 GAP87923.1 - 0.0021 17.9 0.1 0.84 9.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Ubie_methyltran PF01209.18 GAP87923.1 - 0.0043 16.4 0.0 0.0059 16.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAP87923.1 - 0.0074 15.8 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 GAP87923.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DUF4217 PF13959.6 GAP87924.1 - 4.7e-20 71.6 0.0 8.9e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.29 GAP87924.1 - 1e-19 71.0 0.0 9.6e-17 61.3 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP87924.1 - 1.5e-13 51.1 0.0 2.6e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP87924.1 - 0.017 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Band_7 PF01145.25 GAP87925.1 - 1.9e-27 96.5 4.9 3e-27 95.8 4.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 GAP87925.1 - 0.065 12.9 0.2 0.1 12.3 0.2 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Glyco_hyd_65N_2 PF14498.6 GAP87926.1 - 6.9e-60 202.8 0.0 1.6e-59 201.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Amidohydro_1 PF01979.20 GAP87927.1 - 5.1e-22 78.6 0.2 7.6e-10 38.6 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 GAP87927.1 - 8.7e-15 55.1 0.9 3.9e-07 29.9 0.1 2.6 2 1 0 2 2 2 2 Amidohydrolase family Radical_SAM PF04055.21 GAP87927.1 - 0.0029 18.0 0.0 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily DUF3918 PF13056.6 GAP87928.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) zf-RING_4 PF14570.6 GAP87930.1 - 1.8 8.4 7.1 11 5.9 0.0 3.9 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain adh_short PF00106.25 GAP87931.1 - 9.5e-44 149.2 0.4 1.3e-43 148.8 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87931.1 - 2e-31 109.3 0.4 2.5e-31 109.0 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAP87931.1 - 0.007 15.8 0.0 0.0088 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 GAP87931.1 - 0.0094 15.9 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP87931.1 - 0.037 13.5 0.1 0.087 12.3 0.2 1.8 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family Kv2channel PF03521.14 GAP87931.1 - 0.085 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel Presenilin PF01080.17 GAP87933.1 - 3.4 6.3 4.7 4.7 5.9 4.7 1.2 1 0 0 1 1 1 0 Presenilin NmrA PF05368.13 GAP87934.1 - 1.1e-10 41.4 1.3 1.4e-05 24.8 0.3 2.4 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 GAP87934.1 - 4.7e-08 33.1 10.5 1.1e-07 32.0 10.3 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 GAP87934.1 - 0.051 14.0 0.2 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ald_Xan_dh_C2 PF02738.18 GAP87935.1 - 6.3e-209 695.0 0.3 8.8e-209 694.5 0.3 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 GAP87935.1 - 1.1e-48 165.3 0.0 2.2e-48 164.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 GAP87935.1 - 2.8e-31 108.1 0.0 6.4e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 GAP87935.1 - 5.4e-30 103.6 0.6 1.7e-29 102.0 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 GAP87935.1 - 1.2e-29 102.1 0.0 2.7e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 GAP87935.1 - 7.2e-08 32.3 1.7 1.6e-07 31.2 0.1 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 GAP87935.1 - 0.08 13.0 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 DUF218 domain TPD52 PF04201.15 GAP87935.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Tumour protein D52 family PMT PF02366.18 GAP87936.1 - 1.3e-79 267.2 18.1 1.3e-79 267.2 18.1 2.4 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAP87936.1 - 1.5e-65 220.5 17.8 1.5e-65 220.5 17.8 2.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAP87936.1 - 1.3e-36 126.3 2.5 1.9e-36 125.6 2.5 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.22 GAP87937.1 - 6.2e-48 162.5 0.0 1.6e-36 125.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAP87937.1 - 1.2e-28 99.7 0.0 6.4e-18 65.1 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP87937.1 - 4.3e-08 32.8 0.0 1.5e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAP87937.1 - 1.7e-05 24.5 0.0 6.2e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAP87937.1 - 0.0013 18.8 0.0 0.004 17.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAP87937.1 - 0.002 17.6 0.0 0.0047 16.3 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 GAP87937.1 - 0.033 14.1 0.1 0.8 9.6 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 GAP87937.1 - 0.1 12.9 0.1 0.31 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 GAP87937.1 - 0.2 11.4 0.1 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Choline_transpo PF04515.12 GAP87938.1 - 3.9e-26 92.0 21.7 3.9e-26 92.0 21.7 3.1 2 2 0 2 2 2 1 Plasma-membrane choline transporter APH PF01636.23 GAP87941.1 - 6.6e-12 45.9 0.1 1.6e-11 44.6 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP87941.1 - 0.00016 21.4 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 GAP87941.1 - 0.065 12.1 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) WW PF00397.26 GAP87942.1 - 2.5e-10 40.2 6.1 4.9e-10 39.3 6.1 1.5 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.10 GAP87943.1 - 2e-22 79.6 0.0 3.8e-22 78.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 GAP87943.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein Cys_Met_Meta_PP PF01053.20 GAP87944.1 - 2.1e-149 497.2 0.0 2.4e-149 497.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAP87944.1 - 1.6e-08 33.9 0.1 2.7e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAP87944.1 - 2.2e-08 33.8 0.2 4.2e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 GAP87944.1 - 1.1e-07 31.4 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAP87944.1 - 6.5e-06 25.6 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 GAP87944.1 - 0.00089 17.9 0.1 0.0011 17.6 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 GAP87944.1 - 0.001 18.0 0.0 0.0015 17.5 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Asparaginase_C PF17763.1 GAP87944.1 - 0.053 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain MccV PF17508.2 GAP87944.1 - 0.64 10.6 4.4 0.56 10.8 0.2 2.7 3 0 0 3 3 3 0 Microcin V bacteriocin MARVEL PF01284.23 GAP87945.1 - 1.3e-14 54.4 15.3 1.7e-14 54.1 15.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3021 PF11457.8 GAP87945.1 - 0.23 11.8 7.5 2.5 8.5 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) AMP-binding PF00501.28 GAP87946.1 - 3.8e-85 286.0 0.0 4.6e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.32 GAP87947.1 - 0.00022 21.9 11.4 2.6 9.1 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Sporozoite_P67 PF05642.11 GAP87947.1 - 0.025 12.7 8.1 0.041 12.0 8.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_Rpc4 PF05132.14 GAP87947.1 - 2.3 8.6 10.2 5.3 7.5 2.6 2.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 CTD_bind PF04818.13 GAP87948.1 - 1.8e-09 38.3 0.0 3.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 GAP87948.1 - 4e-07 29.8 0.0 9e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Citrate_synt PF00285.21 GAP87949.1 - 1.5e-101 340.1 0.0 2e-101 339.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 GAP87949.1 - 0.033 13.9 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 GAP87950.1 - 2.4e-27 94.7 4.5 3.1e-13 49.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.20 GAP87952.1 - 7.8e-51 172.2 7.8 1.6e-50 171.1 5.4 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAP87952.1 - 1e-16 61.9 0.1 2.7e-16 60.5 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAP87952.1 - 9.3e-10 38.1 0.0 2.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAP87952.1 - 0.011 15.5 1.2 0.013 15.2 0.1 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAP87952.1 - 0.03 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF3425 PF11905.8 GAP87954.1 - 2.6e-17 62.9 0.2 3.8e-17 62.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 GAP87955.1 - 9.7e-05 22.4 10.4 0.0033 17.5 7.6 2.3 1 1 1 2 2 2 2 bZIP transcription factor LppA PF16708.5 GAP87955.1 - 0.077 12.9 1.0 0.12 12.3 0.5 1.5 1 1 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium COG5 PF10392.9 GAP87955.1 - 0.11 12.7 2.3 0.17 12.0 2.3 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF87 PF01935.17 GAP87955.1 - 0.2 11.7 0.2 0.26 11.3 0.2 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain FlaC_arch PF05377.11 GAP87955.1 - 0.21 12.0 0.7 2.1 8.8 0.3 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 GAP87955.1 - 0.25 11.1 1.0 0.41 10.4 1.0 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain bZIP_2 PF07716.15 GAP87955.1 - 2.8 8.1 14.6 2.8 8.1 10.3 2.4 1 1 1 2 2 2 0 Basic region leucine zipper Nic96 PF04097.14 GAP87956.1 - 3.3e-222 739.4 0.0 4e-222 739.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 GAP87956.1 - 0.0069 17.2 17.0 0.0069 17.2 17.0 4.1 2 1 2 4 4 4 1 Nucleoporin FG repeat region FGGY_C PF02782.16 GAP87957.1 - 2.7e-51 174.1 0.3 3.9e-51 173.6 0.3 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAP87957.1 - 3.2e-22 79.3 0.3 2e-19 70.1 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Plectin PF00681.20 GAP87957.1 - 0.098 12.6 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Plectin repeat VTC PF09359.10 GAP87959.1 - 1.5e-92 309.9 2.7 3.5e-92 308.7 2.7 1.6 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 GAP87959.1 - 9.4e-11 42.0 1.8 9.4e-11 42.0 1.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 GAP87959.1 - 3.1e-07 30.7 4.1 0.00065 19.7 0.0 4.2 3 1 1 5 5 5 2 SPX domain SirA PF10747.9 GAP87959.1 - 0.036 14.4 1.1 0.08 13.3 1.1 1.5 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA MgtE PF01769.16 GAP87959.1 - 0.1 13.0 0.4 0.17 12.3 0.4 1.3 1 0 0 1 1 1 0 Divalent cation transporter T3SSipB PF16535.5 GAP87959.1 - 0.17 12.4 2.0 4.3 7.8 0.5 2.6 2 0 0 2 2 2 0 Type III cell invasion protein SipB HNH_2 PF13391.6 GAP87961.1 - 1e-15 57.6 0.2 2e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 HNH endonuclease PAF-AH_p_II PF03403.13 GAP87962.1 - 4e-11 42.1 0.7 2.5e-09 36.1 0.0 2.8 2 1 1 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 GAP87962.1 - 2e-07 30.2 0.7 4.1e-05 22.6 0.0 2.9 3 0 0 3 3 3 2 Chlorophyllase enzyme Chlorophyllase PF07224.11 GAP87962.1 - 0.087 11.8 2.6 0.23 10.4 0.0 2.4 3 0 0 3 3 3 0 Chlorophyllase APP_E2 PF12925.7 GAP87963.1 - 0.00099 18.9 3.7 0.0016 18.2 3.7 1.3 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein SKA2 PF16740.5 GAP87963.1 - 0.38 10.6 2.6 0.36 10.6 0.3 2.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 HAD_2 PF13419.6 GAP87965.1 - 4.7e-08 33.3 0.0 9.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP87965.1 - 0.0032 17.8 0.0 0.0044 17.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 GAP87965.1 - 0.0083 15.6 0.0 0.032 13.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) Terpene_synth PF01397.21 GAP87965.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain p450 PF00067.22 GAP87966.1 - 3.6e-52 177.6 0.0 4.3e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 GAP87967.1 - 7.2e-22 77.8 0.0 2.6e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP87967.1 - 1e-12 48.1 0.0 1.2e-11 44.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP87967.1 - 4.2e-06 26.8 0.0 9.1e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAP87967.1 - 0.0044 16.5 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP87967.1 - 0.14 11.5 0.0 0.43 9.9 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Lactamase_B_2 PF12706.7 GAP87968.1 - 1.1e-26 93.6 0.0 1.2e-25 90.2 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAP87968.1 - 4.1e-10 39.8 0.0 6.6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAP87968.1 - 0.003 17.6 0.6 0.0074 16.3 0.3 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily STT3 PF02516.14 GAP87969.1 - 0.013 14.5 4.7 0.013 14.4 4.7 1.2 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit ECSCR PF15820.5 GAP87969.1 - 0.078 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EPTP PF03736.17 GAP87969.1 - 0.1 12.6 0.7 0.22 11.6 0.1 1.9 2 0 0 2 2 2 0 EPTP domain ASFV_J13L PF05568.11 GAP87971.1 - 4.4 7.0 5.5 2.8 7.6 0.5 2.1 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF1996 PF09362.10 GAP87972.1 - 3.6e-70 236.6 5.7 4.4e-70 236.3 5.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) nos_propeller_2 PF18793.1 GAP87972.1 - 0.094 13.1 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat 2 p450 PF00067.22 GAP87973.1 - 4.4e-50 170.8 0.0 5.8e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CDH-cyt PF16010.5 GAP87975.1 - 9.3e-48 162.3 2.3 1.1e-47 162.1 2.3 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 GAP87975.1 - 0.00048 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 DOMON domain ABC_membrane PF00664.23 GAP87976.1 - 1.1e-78 264.6 35.6 6.2e-40 137.6 12.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAP87976.1 - 2.2e-68 229.0 0.0 5.5e-34 117.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAP87976.1 - 9.8e-12 44.8 5.4 6.1e-05 22.6 0.0 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAP87976.1 - 1.5e-08 34.3 0.2 0.0018 18.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 GAP87976.1 - 5.7e-08 33.1 0.1 0.035 14.4 0.0 3.9 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAP87976.1 - 1.7e-07 31.3 0.0 0.008 16.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAP87976.1 - 1.3e-06 28.9 0.3 0.07 13.5 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain ABC_ATPase PF09818.9 GAP87976.1 - 1.5e-06 27.3 1.3 0.16 10.7 0.0 3.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 GAP87976.1 - 3.8e-06 26.9 0.0 0.075 12.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 GAP87976.1 - 4.4e-05 23.3 0.6 1.1 8.9 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 GAP87976.1 - 0.00018 21.5 0.0 1.6 8.5 0.1 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 GAP87976.1 - 0.00018 21.2 0.8 0.35 10.4 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 GAP87976.1 - 0.00032 21.3 0.9 0.23 11.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain G-alpha PF00503.20 GAP87976.1 - 0.0024 17.1 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit DUF3147 PF11345.8 GAP87976.1 - 0.0025 18.2 12.5 0.0041 17.5 3.8 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3147) AAA_7 PF12775.7 GAP87976.1 - 0.0028 17.2 0.0 0.7 9.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 GAP87976.1 - 0.0041 16.4 0.2 3.4 6.9 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin SbcCD_C PF13558.6 GAP87976.1 - 0.0063 16.7 0.9 7 7.0 0.1 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 GAP87976.1 - 0.009 16.1 0.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 GAP87976.1 - 0.012 15.8 0.1 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 GAP87976.1 - 0.02 14.9 0.2 13 5.8 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 GAP87976.1 - 0.026 15.0 0.7 17 5.8 0.0 4.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAP87976.1 - 0.037 13.9 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 GAP87976.1 - 0.045 13.4 0.0 4.7 6.8 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 GAP87976.1 - 0.051 13.5 0.0 3.1 7.7 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 GAP87976.1 - 0.064 13.7 0.1 4.8 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 GAP87976.1 - 0.065 13.5 0.2 0.39 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 GAP87976.1 - 0.07 12.3 0.3 3.8 6.6 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 GAP87976.1 - 0.14 12.2 2.9 4.6 7.3 0.3 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain ATPase PF06745.13 GAP87976.1 - 0.17 11.2 1.6 1.5 8.2 0.1 2.2 2 0 0 2 2 2 0 KaiC Pox_P21 PF05313.12 GAP87976.1 - 0.38 10.3 3.6 0.42 10.2 0.5 2.3 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Fungal_trans PF04082.18 GAP87977.1 - 1.1e-11 44.2 0.2 5.9e-11 41.9 0.1 2.1 1 1 0 2 2 2 1 Fungal specific transcription factor domain AMP-binding PF00501.28 GAP87978.1 - 1.9e-84 283.8 0.2 2.3e-84 283.4 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP87978.1 - 8.4e-15 55.5 0.1 2.2e-14 54.2 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SH3_3 PF08239.11 GAP87978.1 - 0.009 16.3 0.1 1.6 9.0 0.1 2.6 2 0 0 2 2 2 1 Bacterial SH3 domain Rho_RNA_bind PF07497.12 GAP87978.1 - 0.024 14.5 0.0 0.089 12.7 0.0 1.9 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain Molydop_binding PF01568.21 GAP87978.1 - 0.092 12.8 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain DUF2225 PF09986.9 GAP87978.1 - 0.2 11.4 0.1 0.33 10.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) F-box-like PF12937.7 GAP87979.1 - 3.4e-07 30.0 1.0 7.1e-07 29.0 1.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP87979.1 - 1.9e-06 27.6 3.3 4.2e-06 26.5 3.3 1.7 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.18 GAP87980.1 - 1.1e-10 41.0 0.1 2.3e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP87980.1 - 6.1e-09 35.9 13.0 1.2e-08 34.9 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NADH-u_ox-rdase PF10785.9 GAP87981.1 - 3.7e-29 101.2 0.4 7.8e-29 100.2 0.4 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 GAP87981.1 - 8.4e-25 86.6 0.0 1.2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.12 GAP87982.1 - 1.1e-30 105.5 0.2 1.9e-30 104.7 0.2 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Nucleoporin_FG PF13634.6 GAP87982.1 - 0.066 14.1 7.1 0.65 10.9 5.3 2.8 1 1 1 2 2 2 0 Nucleoporin FG repeat region VIR_N PF15912.5 GAP87982.1 - 0.88 9.1 13.9 0.26 10.9 0.4 3.1 2 1 1 3 3 3 0 Virilizer, N-terminal DUF4366 PF14283.6 GAP87982.1 - 9.8 6.2 14.7 19 5.3 0.7 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4366) DSHCT PF08148.12 GAP87983.1 - 2.3e-53 180.2 0.5 5.6e-53 179.0 0.5 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 GAP87983.1 - 2.7e-39 134.1 0.1 4.6e-38 130.1 0.0 2.3 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 GAP87983.1 - 1.8e-27 97.0 1.0 1.8e-27 97.0 1.0 2.3 3 0 0 3 3 3 1 rRNA-processing arch domain DEAD PF00270.29 GAP87983.1 - 1.7e-17 63.8 0.0 3.8e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP87983.1 - 1.4e-06 28.6 0.1 7.4e-06 26.3 0.1 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP87983.1 - 9e-05 22.5 0.0 0.00023 21.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cwf_Cwc_15 PF04889.12 GAP87983.1 - 0.13 12.0 1.9 0.28 10.9 1.9 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1996 PF09362.10 GAP87984.1 - 5.6e-81 272.0 3.4 6.7e-81 271.7 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF4131 PF13567.6 GAP87985.1 - 0.15 11.7 1.3 0.18 11.4 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Snf7 PF03357.21 GAP87987.1 - 9.5e-07 28.6 25.7 9.5e-07 28.6 25.7 1.6 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 GAP87987.1 - 0.0011 19.0 8.6 0.0036 17.2 8.6 1.7 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Surp PF01805.20 GAP87988.1 - 0.15 12.1 0.7 0.84 9.7 0.2 2.4 2 0 0 2 2 2 0 Surp module bZIP_1 PF00170.21 GAP87989.1 - 7.7e-06 25.9 18.1 1.4e-05 25.1 18.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAP87989.1 - 1.2e-05 25.3 21.8 9.4e-05 22.4 21.8 2.2 1 1 0 1 1 1 1 Basic region leucine zipper NAM-associated PF14303.6 GAP87989.1 - 0.012 16.4 5.2 0.012 16.4 5.2 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain bZIP_Maf PF03131.17 GAP87989.1 - 0.043 14.3 12.5 0.085 13.4 12.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Tho2 PF11262.8 GAP87989.1 - 2.7 7.1 4.5 3.9 6.6 4.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 SARAF PF06682.12 GAP87990.1 - 0.0068 16.1 6.6 0.051 13.2 0.1 2.1 2 0 0 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis S36_mt PF10937.8 GAP87990.1 - 0.065 14.8 4.2 2.1 10.0 0.1 3.0 2 1 1 3 3 3 0 Ribosomal protein S36, mitochondrial DUF4719 PF15843.5 GAP87990.1 - 1.8 8.6 9.5 0.29 11.2 4.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) Peptidase_M24 PF00557.24 GAP87992.1 - 3.1e-46 157.7 0.1 3.6e-46 157.5 0.1 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Ank_2 PF12796.7 GAP87993.1 - 9.2e-33 112.7 9.6 1.2e-10 41.8 0.4 5.7 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP87993.1 - 8.3e-25 86.8 2.0 4.9e-06 27.0 0.0 7.5 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP87993.1 - 4e-16 57.5 5.6 0.032 14.7 0.0 9.4 10 0 0 10 10 10 3 Ankyrin repeat Ank PF00023.30 GAP87993.1 - 7.5e-14 51.5 13.1 0.092 13.2 0.1 10.1 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 GAP87993.1 - 1.2e-10 41.4 6.5 0.035 14.4 0.0 7.6 6 2 2 8 8 8 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 GAP87993.1 - 4.8e-05 23.2 0.1 1.7 8.6 0.0 4.5 3 2 2 5 5 5 2 Domain of unknown function (DUF3447) Glyco_hydro_61 PF03443.14 GAP87995.1 - 2.7e-55 187.5 1.0 3.3e-55 187.2 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HpaB PF03241.13 GAP87995.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal FTA2 PF13095.6 GAP87996.1 - 8.1e-42 143.3 0.0 1.1e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Sugar_tr PF00083.24 GAP87997.1 - 2.7e-81 273.7 21.1 3.2e-81 273.5 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP87997.1 - 5.1e-20 71.7 32.9 6.1e-16 58.3 3.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Arylesterase PF01731.20 GAP87998.1 - 0.15 12.3 0.0 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 Arylesterase Hce2 PF14856.6 GAP87999.1 - 2.5e-11 43.8 0.0 8.7e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF2026 PF09641.10 GAP88001.1 - 0.2 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) p450 PF00067.22 GAP88002.1 - 4e-74 250.0 0.0 4.9e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Podoplanin PF05808.11 GAP88003.1 - 0.0093 16.1 0.2 0.021 15.0 0.2 1.6 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 GAP88003.1 - 0.043 14.4 0.5 0.15 12.7 0.1 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Syndecan PF01034.20 GAP88003.1 - 0.079 12.9 1.4 0.14 12.0 1.4 1.3 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 GAP88003.1 - 0.094 12.8 1.0 0.22 11.6 1.0 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DAP10 PF07213.11 GAP88003.1 - 0.12 12.3 0.4 0.26 11.3 0.1 1.7 2 0 0 2 2 2 0 DAP10 membrane protein EphA2_TM PF14575.6 GAP88003.1 - 0.14 13.1 0.0 0.24 12.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 GAP88003.1 - 0.19 10.5 0.7 0.29 9.9 0.7 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2613 PF11021.8 GAP88003.1 - 0.28 11.3 6.2 0.15 12.2 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) MtrF PF09472.10 GAP88003.1 - 3.4 7.1 5.6 6.8 6.2 5.6 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PARM PF17061.5 GAP88003.1 - 7.1 6.7 13.8 0.4 10.8 7.2 2.2 1 1 0 1 1 1 0 PARM Mucin PF01456.17 GAP88004.1 - 0.0049 16.9 21.6 0.0086 16.1 21.6 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF4215 PF13948.6 GAP88004.1 - 0.1 13.1 1.8 0.16 12.4 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) MatE PF01554.18 GAP88005.1 - 2.3e-06 27.4 15.0 0.00049 19.8 1.9 3.2 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 GAP88005.1 - 0.00013 22.1 5.2 0.00013 22.1 5.2 3.3 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Sterol_MT_C PF08498.10 GAP88006.1 - 4.8e-29 100.5 0.2 8.4e-29 99.7 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 GAP88006.1 - 1.9e-21 76.5 0.0 3.7e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP88006.1 - 1.6e-19 70.4 0.0 3.5e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP88006.1 - 1.5e-18 67.0 0.0 2.3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP88006.1 - 1.5e-11 44.1 0.0 2.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAP88006.1 - 2.3e-11 43.8 0.0 3.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAP88006.1 - 3.6e-11 42.9 0.0 5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 GAP88006.1 - 1.3e-10 41.9 0.0 3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAP88006.1 - 0.00017 21.4 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 GAP88006.1 - 0.00042 19.8 0.0 0.0016 17.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 GAP88006.1 - 0.00095 17.8 0.0 0.0013 17.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 GAP88006.1 - 0.00099 18.7 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.12 GAP88006.1 - 0.0011 18.6 0.0 0.0045 16.6 0.0 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.14 GAP88006.1 - 0.0025 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 GAP88006.1 - 0.0086 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase SPT2 PF08243.11 GAP88006.1 - 0.02 15.4 1.7 0.038 14.5 1.7 1.4 1 0 0 1 1 1 0 SPT2 chromatin protein Methyltransf_32 PF13679.6 GAP88006.1 - 0.032 14.2 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 GAP88006.1 - 0.045 13.0 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain TehB PF03848.14 GAP88006.1 - 0.046 13.1 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Transket_pyr PF02779.24 GAP88007.1 - 1.6e-46 158.2 0.0 2.2e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAP88007.1 - 1.3e-36 125.3 0.0 3.7e-36 123.8 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF3558 PF12079.8 GAP88008.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Asp PF00026.23 GAP88009.1 - 5.2e-64 216.7 4.2 6.5e-64 216.3 4.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP88009.1 - 1.4e-10 41.7 1.6 6.9e-08 32.9 1.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Hyr1 PF15789.5 GAP88009.1 - 0.092 12.3 0.2 4.3 6.9 0.0 3.2 3 0 0 3 3 3 0 Hyphally regulated cell wall GPI-anchored protein 1 Aminotran_5 PF00266.19 GAP88010.1 - 1.9e-30 106.1 0.0 5e-21 75.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V p450 PF00067.22 GAP88012.1 - 8.5e-55 186.3 0.0 1.1e-54 186.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FeS_assembly_P PF01883.19 GAP88012.1 - 0.051 13.7 0.1 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein Pex16 PF08610.10 GAP88013.1 - 4.1e-133 443.5 2.8 4.6e-133 443.4 2.8 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) NUDIX PF00293.28 GAP88014.1 - 7.1e-08 32.6 0.0 7.7e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain SWIRM PF04433.17 GAP88015.1 - 2.6e-14 53.3 0.1 2e-13 50.5 0.1 2.1 2 0 0 2 2 2 1 SWIRM domain Terpene_synth_C PF03936.16 GAP88016.1 - 2.3e-05 23.9 0.8 5.8e-05 22.6 0.1 2.1 1 1 1 2 2 2 1 Terpene synthase family, metal binding domain Rubi_NSP_C PF12601.8 GAP88016.1 - 0.0019 18.3 0.1 0.16 12.1 0.1 2.7 3 0 0 3 3 3 1 Rubivirus non-structural protein Guanylate_cyc PF00211.20 GAP88016.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 GAP88017.1 - 0.002 18.5 0.0 0.01 16.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 GAP88017.1 - 0.0026 18.4 0.4 0.0026 18.4 0.4 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family NACHT PF05729.12 GAP88017.1 - 0.0042 17.0 0.0 0.035 14.0 0.0 2.3 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 GAP88017.1 - 0.014 15.2 0.0 0.049 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF676 PF05057.14 GAP88017.1 - 0.02 14.4 0.0 0.083 12.4 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) NB-ARC PF00931.22 GAP88017.1 - 0.047 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 GAP88017.1 - 0.063 13.0 0.4 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 GAP88017.1 - 0.17 12.2 0.2 0.52 10.7 0.2 1.8 1 0 0 1 1 1 0 RNA helicase Beta-lactamase PF00144.24 GAP88018.1 - 1e-35 123.6 0.5 1.7e-35 122.9 0.5 1.2 1 0 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.18 GAP88018.1 - 0.0031 17.6 6.0 0.0067 16.5 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_90 PF05686.12 GAP88019.1 - 4.1e-10 39.1 0.1 1.4e-09 37.4 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 PRIMA1 PF16101.5 GAP88019.1 - 0.43 10.6 2.9 1.1 9.3 2.9 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Lipase_GDSL PF00657.22 GAP88023.1 - 1.1e-11 45.1 0.0 1.4e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAP88023.1 - 9.6e-06 26.1 0.8 2.1e-05 25.0 0.3 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Plant_tran PF04827.14 GAP88023.1 - 0.067 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Plant transposon protein zf-C2H2_jaz PF12171.8 GAP88024.1 - 3.7e-07 30.2 1.8 6.2e-07 29.5 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP88024.1 - 0.00042 20.6 0.5 0.00068 19.9 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 GAP88024.1 - 0.05 14.1 0.7 0.085 13.3 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP88024.1 - 0.063 14.2 0.3 0.12 13.3 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAP88024.1 - 0.079 13.3 0.5 0.12 12.7 0.5 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 GAP88024.1 - 0.14 12.3 1.3 0.23 11.6 1.3 1.3 1 0 0 1 1 1 0 DBF zinc finger DUF1691 PF07950.11 GAP88025.1 - 3.1e-41 140.4 1.8 5.4e-33 113.9 1.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sulfotransfer_4 PF17784.1 GAP88026.1 - 6.7e-55 186.2 0.0 7.9e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 GAP88026.1 - 1.1e-05 25.9 0.1 8.3e-05 23.1 0.0 2.3 2 1 1 3 3 3 1 Sulfotransferase family CPT PF07931.12 GAP88026.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sulfotransfer_1 PF00685.27 GAP88026.1 - 0.17 11.3 0.0 0.5 9.8 0.0 1.9 1 1 0 1 1 1 0 Sulfotransferase domain CFEM PF05730.11 GAP88028.1 - 9.1e-13 48.1 10.9 1.9e-12 47.1 10.9 1.6 1 0 0 1 1 1 1 CFEM domain p450 PF00067.22 GAP88029.1 - 1.5e-68 231.6 0.0 2e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AATase PF07247.12 GAP88030.1 - 0.0044 15.6 0.0 0.83 8.1 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase Pro-kuma_activ PF09286.11 GAP88031.1 - 5.4e-46 156.4 0.0 8.2e-46 155.8 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAP88031.1 - 0.0036 16.6 1.8 0.0062 15.8 1.8 1.3 1 0 0 1 1 1 1 Subtilase family peroxidase PF00141.23 GAP88032.1 - 1.8e-88 296.1 0.0 2e-45 155.3 0.0 2.3 2 0 0 2 2 2 2 Peroxidase MFS_1 PF07690.16 GAP88033.1 - 6.4e-26 91.1 35.1 6.4e-26 91.1 35.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily CcmD PF04995.14 GAP88033.1 - 6.8 6.9 9.8 1.8 8.7 4.8 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Methyltrn_RNA_3 PF02598.17 GAP88034.1 - 9.2e-91 304.3 0.0 1.1e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Thioredoxin PF00085.20 GAP88035.1 - 6e-27 93.6 0.0 7.9e-27 93.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GAP88035.1 - 2.8e-05 23.6 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 GAP88035.1 - 5.5e-05 23.6 0.1 0.00031 21.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAP88035.1 - 0.00012 22.4 0.0 0.00027 21.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 GAP88035.1 - 0.004 17.3 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 GAP88035.1 - 0.029 13.3 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosducin AhpC-TSA PF00578.21 GAP88035.1 - 0.052 13.5 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 GAP88035.1 - 0.088 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 GAP88035.1 - 0.16 11.7 0.1 1.1 9.0 0.1 1.9 1 1 1 2 2 2 0 Redoxin Ank_2 PF12796.7 GAP88036.1 - 8.7e-32 109.6 0.0 1.2e-11 45.0 0.0 3.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP88036.1 - 6.7e-27 93.2 0.2 1.5e-06 28.4 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 GAP88036.1 - 6.8e-27 92.7 0.2 3.8e-05 23.9 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 GAP88036.1 - 1e-22 80.2 0.2 4e-06 27.3 0.0 5.8 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88036.1 - 5.4e-22 75.5 0.1 0.00019 21.6 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Sugar_tr PF00083.24 GAP88037.1 - 9.1e-61 206.1 13.2 1.3e-60 205.5 13.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP88037.1 - 2.6e-07 29.9 42.8 0.00042 19.4 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VGCC_beta4Aa_N PF12052.8 GAP88037.1 - 0.059 13.5 0.7 6.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Rsm22 PF09243.10 GAP88038.1 - 5.5e-30 104.6 0.0 6.2e-29 101.1 0.0 2.5 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_12 PF08242.12 GAP88038.1 - 0.061 14.1 0.0 0.33 11.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain TP_methylase PF00590.20 GAP88039.1 - 3.6e-46 157.8 0.3 5.9e-46 157.1 0.3 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.6 GAP88039.1 - 1.5e-12 47.0 0.0 4.7e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 GAP88039.1 - 2.1e-12 47.4 0.0 3.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 GAP88039.1 - 6.7e-12 44.6 0.1 1.9e-11 43.2 0.1 1.9 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central FAD_binding_3 PF01494.19 GAP88041.1 - 5.1e-18 65.4 0.1 9.8e-18 64.5 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP88041.1 - 3.3e-10 39.7 0.9 0.00023 20.5 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP88041.1 - 6.6e-07 28.8 0.2 1.2e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP88041.1 - 8.6e-07 28.9 7.3 0.0026 17.4 1.3 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP88041.1 - 1.8e-06 28.1 0.5 3.9e-06 27.0 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAP88041.1 - 2.2e-06 26.7 0.2 0.016 13.9 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 GAP88041.1 - 1.7e-05 25.3 0.1 0.0051 17.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP88041.1 - 0.00033 19.9 0.2 0.0008 18.6 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAP88041.1 - 0.0016 17.9 1.6 0.011 15.1 1.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAP88041.1 - 0.015 14.6 0.0 0.067 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAP88041.1 - 0.021 13.7 0.1 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 GAP88041.1 - 0.041 13.9 0.4 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAP88041.1 - 0.073 12.1 0.6 6.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NACHT PF05729.12 GAP88042.1 - 1.4e-08 34.9 0.7 3.7e-08 33.5 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GAP88042.1 - 0.0033 17.8 4.0 0.0053 17.2 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 GAP88042.1 - 0.021 14.0 0.5 0.072 12.3 0.5 1.9 1 1 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 GAP88042.1 - 0.12 12.4 0.2 2.6 8.1 0.2 2.8 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 GAP88042.1 - 2.2 7.7 6.1 8.8 5.7 0.1 3.1 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain NUDIX PF00293.28 GAP88043.1 - 2e-19 69.9 0.4 2.4e-19 69.7 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain LIAS_N PF16881.5 GAP88044.1 - 1.6e-17 63.9 0.0 2.9e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 GAP88044.1 - 2.7e-05 24.6 0.1 0.0035 17.7 0.0 2.4 1 1 0 2 2 2 2 Radical SAM superfamily DUF676 PF05057.14 GAP88045.1 - 2.3e-05 24.0 0.0 3.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 GAP88045.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAP88045.1 - 0.012 16.3 0.0 0.014 16.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 GAP88047.1 - 5.5e-05 22.9 0.0 0.00089 18.9 0.0 2.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 GAP88047.1 - 0.00053 18.6 0.0 0.013 14.0 0.0 2.1 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 GAP88047.1 - 0.001 18.4 0.7 0.0055 16.0 0.3 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAP88047.1 - 0.0031 18.1 28.8 0.0067 17.0 28.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 GAP88047.1 - 0.0034 16.3 0.0 0.0067 15.4 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 GAP88047.1 - 0.0074 15.8 0.0 0.03 13.8 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 GAP88047.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.9 GAP88047.1 - 0.022 14.3 4.6 0.053 13.0 4.6 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase Esterase PF00756.20 GAP88047.1 - 0.025 14.3 0.1 0.052 13.2 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Chlorophyllase PF07224.11 GAP88047.1 - 0.032 13.3 0.0 0.068 12.2 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase Abhydrolase_1 PF00561.20 GAP88047.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 GAP88047.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 GAP88047.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 GAP88047.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) HD PF01966.22 GAP88048.1 - 0.005 17.1 0.0 0.0076 16.5 0.0 1.3 1 0 0 1 1 1 1 HD domain HMG_box PF00505.19 GAP88049.1 - 3.1e-11 43.5 1.0 3.5e-11 43.4 0.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAP88049.1 - 0.00096 19.7 0.0 0.0023 18.5 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain Dynamin_N PF00350.23 GAP88050.1 - 1.4e-14 54.5 0.0 5.2e-14 52.6 0.0 2.1 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAP88050.1 - 9.6e-07 28.9 0.0 5.2e-05 23.3 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP88050.1 - 1.5e-05 24.9 2.2 0.00024 21.0 0.1 3.7 3 2 2 5 5 5 1 RsgA GTPase ABC_tran PF00005.27 GAP88050.1 - 0.0002 21.9 0.0 0.00083 19.9 0.0 2.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 GAP88050.1 - 0.0011 19.4 0.2 0.0076 16.6 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain ApoLp-III PF07464.11 GAP88050.1 - 0.052 13.6 0.7 0.31 11.1 0.3 2.5 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Roc PF08477.13 GAP88050.1 - 0.059 13.6 0.0 0.37 11.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 GAP88050.1 - 0.39 11.2 7.1 2 8.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF1772 PF08592.11 GAP88052.1 - 6.8e-05 23.2 2.4 8.5e-05 22.9 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Clr5 PF14420.6 GAP88056.1 - 2.6e-20 72.4 2.0 8.4e-20 70.7 1.5 2.2 2 0 0 2 2 2 1 Clr5 domain Peptidase_C1_2 PF03051.15 GAP88059.1 - 8e-134 446.7 0.0 2.1e-66 224.5 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.23 GAP88059.1 - 2.1e-06 28.0 0.1 0.023 14.8 0.2 2.4 3 0 0 3 3 3 2 Papain family cysteine protease eIF-5a PF01287.20 GAP88060.1 - 1.6e-05 24.9 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Med25_SD1 PF11235.8 GAP88060.1 - 0.12 12.7 2.7 0.24 11.7 0.2 2.4 2 1 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 NFACT-C PF11923.8 GAP88061.1 - 1.6e-37 127.6 0.1 1.6e-37 127.6 0.1 2.8 2 0 0 2 2 2 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 GAP88061.1 - 1.3e-32 112.6 0.0 3.7e-32 111.2 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 GAP88061.1 - 9.9e-30 103.7 1.7 9.9e-30 103.7 1.7 2.6 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) GREB1 PF15782.5 GAP88061.1 - 3.3 4.7 3.9 4.7 4.2 3.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4192 PF13830.6 GAP88061.1 - 4.5 7.3 22.1 0.74 9.8 11.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Trypan_PARP PF05887.11 GAP88062.1 - 0.011 15.8 10.4 0.011 15.8 10.4 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) bVLRF1 PF18826.1 GAP88063.1 - 1.2e-62 210.2 0.1 1.9e-62 209.5 0.1 1.3 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 GAP88063.1 - 4.4e-06 26.9 0.0 1.4e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 GAP88063.1 - 0.013 15.9 0.2 0.042 14.3 0.2 1.9 1 0 0 1 1 1 0 Ankyrin repeat CFEM PF05730.11 GAP88064.1 - 9e-05 22.5 2.3 9e-05 22.5 2.3 2.2 2 0 0 2 2 2 1 CFEM domain Myosin_head PF00063.21 GAP88066.1 - 3e-265 881.7 0.0 1.6e-264 879.3 0.0 2.3 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 GAP88066.1 - 1.6e-13 50.2 0.2 4.9e-13 48.7 0.2 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 GAP88066.1 - 2.2e-08 32.5 65.8 2.2e-08 32.5 65.8 5.1 2 2 2 4 4 4 2 Myosin tail AAA_22 PF13401.6 GAP88066.1 - 0.15 12.3 0.0 0.15 12.3 0.0 5.0 5 0 0 5 5 5 0 AAA domain Rota_NSP4 PF01452.16 GAP88066.1 - 0.43 10.2 3.8 2.8 7.6 3.8 2.5 1 0 0 1 1 1 0 Rotavirus non structural protein PKcGMP_CC PF16808.5 GAP88066.1 - 0.79 9.6 35.1 3.1 7.7 0.0 8.9 8 0 0 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3145 PF11343.8 GAP88066.1 - 1.1 8.8 5.5 17 5.0 0.1 4.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3145) UDPG_MGDP_dh_N PF03721.14 GAP88066.1 - 1.5 8.4 4.9 2.7 7.5 3.6 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-C3H1 PF10650.9 GAP88067.1 - 0.00099 18.8 0.4 0.0015 18.2 0.4 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain zf-CCCH_4 PF18044.1 GAP88067.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger DUF4449 PF14613.6 GAP88068.1 - 0.0077 16.4 0.0 0.025 14.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) DUF445 PF04286.12 GAP88068.1 - 0.62 9.8 3.2 0.85 9.4 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Abhydrolase_1 PF00561.20 GAP88069.1 - 5.8e-24 85.1 0.1 7.1e-23 81.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 GAP88069.1 - 4.9e-22 77.3 0.1 9e-22 76.4 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 GAP88069.1 - 2.9e-05 23.5 0.0 0.0051 16.1 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 GAP88069.1 - 0.00027 20.7 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Pet191_N PF10203.9 GAP88070.1 - 2.3e-16 59.9 0.7 3.2e-16 59.4 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Metallophos PF00149.28 GAP88071.1 - 1.1e-09 39.1 4.3 6e-09 36.7 4.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAP88071.1 - 2.2e-05 24.7 0.9 6.4e-05 23.2 0.5 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Macoilin PF09726.9 GAP88071.1 - 0.06 11.9 4.0 0.094 11.3 4.0 1.2 1 0 0 1 1 1 0 Macoilin family Form-deh_trans PF09163.11 GAP88071.1 - 0.16 11.8 0.6 0.61 9.9 0.6 2.0 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane TAL_FSA PF00923.19 GAP88072.1 - 2.2e-96 322.6 0.4 2.5e-96 322.4 0.4 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase SNase PF00565.17 GAP88073.1 - 8.5e-70 232.1 0.4 6e-21 75.0 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 GAP88073.1 - 1.5e-23 83.1 0.0 5.4e-23 81.3 0.0 1.9 2 0 0 2 2 2 1 Tudor domain SMN PF06003.12 GAP88073.1 - 0.00012 21.5 0.1 0.00028 20.2 0.1 1.7 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Itfg2 PF15907.5 GAP88073.1 - 0.1 11.6 0.1 0.64 9.0 0.0 2.1 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Sod_Cu PF00080.20 GAP88074.1 - 9e-47 158.8 5.1 1e-46 158.6 5.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CNH PF00780.22 GAP88075.1 - 4.3e-61 206.9 0.0 7.9e-61 206.1 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 GAP88075.1 - 2e-30 106.4 0.3 3.3e-30 105.7 0.3 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 GAP88075.1 - 1.3e-11 44.7 0.0 9.9e-11 41.9 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 GAP88075.1 - 0.00022 21.7 0.1 0.0049 17.4 0.1 2.7 1 1 0 1 1 1 1 PH domain PH_16 PF17838.1 GAP88075.1 - 0.0019 18.1 0.1 3.2 7.6 0.0 2.7 2 0 0 2 2 2 2 PH domain NACHT PF05729.12 GAP88076.1 - 9.3e-10 38.7 0.5 2.6e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GAP88076.1 - 2.9e-07 31.0 0.6 1.6e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain SesA PF17107.5 GAP88076.1 - 7.8e-06 26.1 0.1 1.8e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 GAP88076.1 - 0.0003 21.1 0.1 0.0012 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAP88076.1 - 0.0026 17.0 0.0 0.011 15.0 0.0 2.0 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 GAP88076.1 - 0.0098 15.8 0.1 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 GAP88076.1 - 0.013 15.3 0.1 0.031 14.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 GAP88076.1 - 0.024 15.1 0.0 0.088 13.3 0.0 2.0 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 GAP88076.1 - 0.04 13.2 0.0 0.083 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 GAP88076.1 - 0.043 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAP88076.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 GAP88076.1 - 0.063 13.7 0.0 0.21 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 GAP88076.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_hydro_43 PF04616.14 GAP88077.1 - 9.6e-26 90.7 0.0 1.3e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FG-GAP_2 PF14312.6 GAP88077.1 - 0.47 10.7 4.2 39 4.6 0.0 3.5 3 0 0 3 3 3 0 FG-GAP repeat Methyltransf_23 PF13489.6 GAP88078.1 - 3.4e-21 75.8 0.0 4.9e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP88078.1 - 1.8e-13 51.0 0.0 3.8e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP88078.1 - 1e-10 42.1 0.0 1.9e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP88078.1 - 4.4e-09 36.3 0.0 8.6e-08 32.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP88078.1 - 3.2e-08 34.2 0.0 1.1e-07 32.5 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP88078.1 - 1.3e-05 24.7 0.0 0.00013 21.4 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAP88078.1 - 0.00084 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 GAP88078.1 - 0.0021 17.5 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 GAP88078.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 GAP88078.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 GAP88078.1 - 0.029 14.5 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase CMAS PF02353.20 GAP88078.1 - 0.054 12.8 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 GAP88078.1 - 0.072 12.4 0.0 1.5 8.1 0.0 2.6 2 1 0 2 2 2 0 O-methyltransferase domain BTB PF00651.31 GAP88079.1 - 2.7e-26 92.0 0.2 1.6e-13 50.8 0.3 3.1 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 GAP88079.1 - 7.2e-07 29.7 0.1 1.6e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAP88079.1 - 1.2e-06 28.7 0.1 0.0079 16.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAP88079.1 - 1.9e-06 28.3 0.1 5.5e-06 26.8 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP88079.1 - 3e-06 27.4 0.1 9.6e-06 25.8 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88079.1 - 0.00039 20.6 0.1 0.59 10.9 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Lipase_GDSL_2 PF13472.6 GAP88080.1 - 6.4e-09 36.5 0.0 8.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP88080.1 - 0.00012 22.1 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 GAP88080.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Cadherin_pro PF08758.11 GAP88081.1 - 0.62 10.3 2.9 36 4.6 0.0 3.3 3 0 0 3 3 3 0 Cadherin prodomain like GH131_N PF18271.1 GAP88082.1 - 9.8e-83 277.8 0.4 1.1e-82 277.6 0.4 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain DUF3433 PF11915.8 GAP88083.1 - 2.8e-28 98.2 21.0 8.2e-26 90.3 5.2 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF5134 PF17197.4 GAP88083.1 - 0.63 9.9 10.5 0.34 10.8 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5134) Tyrosinase PF00264.20 GAP88085.1 - 5.4e-34 118.4 1.2 1.1e-32 114.1 1.2 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase GNAT_acetyltr_2 PF13718.6 GAP88086.1 - 3.9e-92 307.8 0.0 6.5e-92 307.0 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 GAP88086.1 - 1e-81 274.1 0.0 1.7e-81 273.4 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 GAP88086.1 - 9.4e-63 211.2 0.0 1.6e-62 210.5 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 GAP88086.1 - 2.5e-31 107.4 0.1 7.2e-31 106.0 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 GAP88086.1 - 0.015 15.1 0.1 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAP88086.1 - 0.022 15.0 0.0 0.58 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Preseq_ALAS PF09029.10 GAP88087.1 - 0.0016 18.9 6.3 0.0099 16.4 1.4 2.7 1 1 1 2 2 2 2 5-aminolevulinate synthase presequence Cyto_heme_lyase PF01265.17 GAP88087.1 - 5.2 6.6 7.5 9 5.8 0.4 2.1 1 1 1 2 2 2 0 Cytochrome c/c1 heme lyase adh_short PF00106.25 GAP88088.1 - 2.7e-37 128.1 0.2 3.7e-37 127.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88088.1 - 3.4e-33 115.1 0.1 5.6e-33 114.4 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88088.1 - 5.7e-14 52.4 0.4 7.8e-14 52.0 0.4 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 GAP88088.1 - 0.022 14.5 0.5 0.19 11.5 0.8 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 GAP88088.1 - 0.027 13.6 0.1 0.031 13.4 0.1 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_M50B PF13398.6 GAP88089.1 - 8.6e-59 198.5 21.7 1.1e-58 198.2 21.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 GAP88089.1 - 0.0031 16.8 0.3 0.0066 15.7 0.3 1.5 1 0 0 1 1 1 1 Peptidase family M50 YlaC PF10777.9 GAP88089.1 - 0.081 12.8 0.2 0.081 12.8 0.2 1.9 2 1 0 2 2 2 0 Inner membrane protein YlaC Peptidase_M41 PF01434.18 GAP88089.1 - 0.2 11.5 0.2 0.31 10.9 0.2 1.2 1 0 0 1 1 1 0 Peptidase family M41 Peptidase_M36 PF02128.15 GAP88089.1 - 0.23 10.6 0.1 0.34 10.0 0.1 1.2 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) Patched PF02460.18 GAP88089.1 - 4.6 5.2 7.6 6.6 4.7 7.6 1.1 1 0 0 1 1 1 0 Patched family EF-hand_1 PF00036.32 GAP88090.1 - 1.8e-13 49.0 1.0 8.1e-05 21.9 0.1 4.3 4 0 0 4 4 4 2 EF hand ZZ PF00569.17 GAP88090.1 - 2.6e-11 43.1 5.6 4.6e-11 42.4 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.6 GAP88090.1 - 2.3e-09 36.4 2.8 0.00014 21.5 0.1 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 GAP88090.1 - 2e-08 34.6 8.6 0.00046 20.6 0.2 4.8 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 GAP88090.1 - 4e-07 29.2 0.7 0.059 12.9 0.1 3.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 GAP88090.1 - 6.2e-06 26.0 0.2 0.33 10.8 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain pair C1_2 PF03107.16 GAP88090.1 - 0.021 15.2 5.2 0.04 14.3 5.2 1.4 1 0 0 1 1 1 0 C1 domain Dockerin_1 PF00404.18 GAP88090.1 - 0.024 14.8 0.4 0.28 11.4 0.1 2.6 2 0 0 2 2 2 0 Dockerin type I domain UBM PF14377.6 GAP88090.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin binding region ADH_N PF08240.12 GAP88091.1 - 3.9e-05 23.5 0.5 0.00011 22.0 0.5 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP88091.1 - 0.00087 19.3 1.7 0.0037 17.2 0.7 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase p450 PF00067.22 GAP88092.1 - 7.1e-52 176.7 0.0 1e-51 176.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.17 GAP88092.1 - 0.016 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Reticulon Methyltransf_23 PF13489.6 GAP88093.1 - 3.9e-19 69.1 0.0 5.4e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP88093.1 - 8.8e-11 42.4 0.0 2.1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP88093.1 - 4.4e-08 33.1 0.0 4.4e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP88093.1 - 1.6e-07 31.9 0.0 6.6e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP88093.1 - 5.9e-07 30.0 0.0 1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 GAP88093.1 - 0.00027 20.7 0.0 0.00042 20.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 GAP88093.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 GAP88093.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 GAP88093.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 GAP88093.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Egh16-like PF11327.8 GAP88094.1 - 3.7e-50 170.9 9.8 3.7e-50 170.9 9.8 1.8 2 0 0 2 2 2 1 Egh16-like virulence factor DUF4149 PF13664.6 GAP88096.1 - 5.4e-21 74.8 4.6 5.4e-21 74.8 4.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Erg28 PF03694.13 GAP88096.1 - 0.0066 16.8 0.2 0.01 16.2 0.2 1.3 1 0 0 1 1 1 1 Erg28 like protein Abhydrolase_1 PF00561.20 GAP88097.1 - 1.7e-16 60.7 0.0 2.6e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP88097.1 - 1.3e-13 50.8 0.0 1.8e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAP88097.1 - 7.9e-12 46.2 10.3 1.9e-11 45.0 9.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.9 GAP88097.1 - 0.00029 20.1 0.1 0.00041 19.6 0.1 1.1 1 0 0 1 1 1 1 Abhydrolase domain containing 18 DUF1100 PF06500.11 GAP88097.1 - 0.0056 15.5 0.0 0.0074 15.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.13 GAP88097.1 - 0.036 13.9 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 GAP88097.1 - 0.037 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 GAP88097.1 - 0.053 13.3 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 GAP88097.1 - 0.056 13.2 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 GAP88097.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase UPF0227 PF05728.12 GAP88097.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) BAAT_C PF08840.11 GAP88097.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal CobT PF06213.12 GAP88098.1 - 0.032 13.6 1.2 0.33 10.3 0.1 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Dicty_REP PF05086.12 GAP88098.1 - 3.7 5.4 5.2 6.2 4.7 5.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Abhydrolase_6 PF12697.7 GAP88099.1 - 2e-12 48.2 0.1 4e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP88099.1 - 1e-08 34.7 0.2 2.8e-08 33.4 0.1 1.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP88099.1 - 1.6e-08 34.5 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAP88099.1 - 6.7e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAP88099.1 - 0.026 14.3 0.6 0.083 12.7 0.2 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 GAP88099.1 - 0.028 14.2 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 GAP88099.1 - 0.031 14.1 0.2 0.068 13.0 0.2 1.5 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S15 PF02129.18 GAP88099.1 - 0.061 12.9 0.2 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1057 PF06342.12 GAP88099.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 GAP88099.1 - 0.1 12.3 0.3 0.76 9.4 0.1 2.1 2 0 0 2 2 2 0 PGAP1-like protein Peptidase_S9 PF00326.21 GAP88099.1 - 0.11 12.0 0.1 0.48 9.9 0.1 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family NMT_C PF02799.15 GAP88100.1 - 4.6e-85 284.4 0.1 6.7e-85 283.9 0.1 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 GAP88100.1 - 6.1e-74 247.2 0.1 4.5e-73 244.4 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 GAP88100.1 - 0.00031 20.8 0.0 0.0078 16.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AhpC-TSA PF00578.21 GAP88101.1 - 4.2e-30 104.2 0.0 5.6e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAP88101.1 - 3.8e-14 52.6 0.0 5.1e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GAP88101.1 - 5.3e-12 45.4 0.2 9.9e-12 44.5 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_4 PF13418.6 GAP88102.1 - 3.8e-17 62.0 0.5 8.8e-06 25.6 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 GAP88102.1 - 6.1e-13 48.1 0.1 0.00048 19.7 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 GAP88102.1 - 9.6e-13 47.9 5.1 0.00091 19.4 1.0 5.2 3 1 1 4 4 4 3 Kelch motif Kelch_3 PF13415.6 GAP88102.1 - 7e-12 45.3 18.6 2e-09 37.5 0.0 6.5 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_5 PF13854.6 GAP88102.1 - 1.9e-11 43.7 10.6 2.3e-06 27.5 0.2 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 GAP88102.1 - 1.8e-08 34.0 3.0 0.00032 20.5 0.0 4.8 4 1 0 4 4 4 1 Kelch motif BTB PF00651.31 GAP88102.1 - 0.027 14.7 0.1 0.061 13.6 0.1 1.6 1 0 0 1 1 1 0 BTB/POZ domain RAG2 PF03089.14 GAP88102.1 - 0.19 10.7 0.0 0.48 9.4 0.0 1.6 1 1 0 1 1 1 0 Recombination activating protein 2 Peptidase_S15 PF02129.18 GAP88103.1 - 5.5e-05 22.9 0.3 0.00046 19.9 0.1 2.1 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 GAP88103.1 - 0.0001 22.0 0.2 0.23 11.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF3336 PF11815.8 GAP88104.1 - 4.9e-32 110.5 0.1 1.5e-31 109.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAP88104.1 - 7.4e-21 75.3 0.0 1.4e-20 74.4 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Zn_clus PF00172.18 GAP88105.1 - 2.2e-19 69.3 25.4 9.8e-10 38.4 8.0 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP88105.1 - 7.3e-12 44.9 0.6 1.6e-11 43.8 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 GAP88106.1 - 3.9e-42 144.4 0.0 5.2e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DMA PF03474.14 GAP88106.1 - 0.026 14.1 0.0 0.078 12.6 0.0 1.8 1 0 0 1 1 1 0 DMRTA motif RHH_1 PF01402.21 GAP88106.1 - 0.033 14.1 0.2 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Gpr1_Fun34_YaaH PF01184.19 GAP88109.1 - 5.9e-23 81.6 17.7 7.4e-23 81.2 17.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pkinase PF00069.25 GAP88110.1 - 1.1e-30 106.9 0.0 1.9e-15 57.0 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP88110.1 - 1.8e-09 37.2 0.0 7.5e-06 25.4 0.0 3.1 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 GAP88110.1 - 0.00013 22.0 1.1 0.00085 19.3 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 GAP88110.1 - 0.00079 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAP88110.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Helo_like_N PF17111.5 GAP88111.1 - 1.3e-18 67.1 2.1 1.8e-18 66.7 2.1 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins F-box_4 PF15966.5 GAP88111.1 - 0.0071 16.2 0.3 0.015 15.2 0.3 1.5 1 0 0 1 1 1 1 F-box SesA PF17107.5 GAP88111.1 - 0.026 14.7 0.1 0.026 14.7 0.1 2.0 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Thymidylat_synt PF00303.19 GAP88111.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Thymidylate synthase Ank_2 PF12796.7 GAP88112.1 - 7.7e-42 141.8 10.2 2.7e-19 69.5 0.9 4.8 3 1 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88112.1 - 1.1e-32 112.0 11.6 5.6e-11 42.7 0.1 5.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAP88112.1 - 6.1e-30 102.3 13.0 3.4e-07 30.4 0.0 6.8 5 1 1 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 GAP88112.1 - 2.2e-27 92.1 8.6 2.9e-05 24.1 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 GAP88112.1 - 1.8e-24 85.5 25.4 3.4e-10 40.0 0.4 6.3 2 1 5 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.12 GAP88112.1 - 7.4e-11 42.2 0.0 1.7e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP88112.1 - 0.00037 20.9 0.0 0.0016 18.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 GAP88112.1 - 0.057 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Glyco_hydro_35 PF01301.19 GAP88114.1 - 9.2e-91 304.7 1.3 1.7e-90 303.8 1.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 GAP88114.1 - 2.4e-58 196.9 0.0 3.7e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 GAP88114.1 - 5.1e-54 181.7 1.0 1.6e-31 109.2 0.0 3.2 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 GAP88114.1 - 6.1e-26 89.8 0.2 1.8e-25 88.3 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 GAP88114.1 - 5.5e-07 29.3 1.0 1.2e-05 24.9 0.7 2.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_53 PF07745.13 GAP88114.1 - 0.034 13.1 0.5 0.085 11.8 0.1 1.8 3 0 0 3 3 3 0 Glycosyl hydrolase family 53 Maf PF02545.14 GAP88115.1 - 1e-47 162.1 0.0 1.3e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.26 GAP88116.1 - 1.4e-07 31.3 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.12 GAP88116.1 - 0.048 13.0 0.5 0.051 12.9 0.5 1.1 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family tRNA-synt_2b PF00587.25 GAP88117.1 - 1.7e-32 112.9 0.0 2.9e-31 108.8 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAP88117.1 - 1.6e-07 31.3 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain LOH1CR12 PF10158.9 GAP88118.1 - 0.016 15.2 0.1 1.9 8.5 0.1 2.3 2 0 0 2 2 2 0 Tumour suppressor protein RTBV_P46 PF06216.11 GAP88118.1 - 0.05 12.5 0.1 0.078 11.9 0.1 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein bZIP_1 PF00170.21 GAP88119.1 - 0.00024 21.1 8.7 0.00054 20.0 8.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAP88119.1 - 0.013 15.6 9.8 0.037 14.1 9.8 1.7 1 0 0 1 1 1 0 Basic region leucine zipper FlxA PF14282.6 GAP88119.1 - 0.1 12.6 11.2 0.22 11.5 11.2 1.5 1 0 0 1 1 1 0 FlxA-like protein HAUS6_N PF14661.6 GAP88119.1 - 0.32 10.5 3.1 0.17 11.4 1.1 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DAO PF01266.24 GAP88120.1 - 9.1e-43 147.2 0.9 1e-42 147.0 0.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP88120.1 - 6.1e-05 23.2 1.0 0.00017 21.7 1.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAP88120.1 - 0.00093 18.5 0.1 0.0017 17.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 GAP88120.1 - 0.0028 17.0 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP88120.1 - 0.0054 16.7 1.0 0.018 15.0 0.2 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAP88120.1 - 0.054 12.7 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP88120.1 - 0.2 10.7 5.3 1.1 8.2 5.3 2.0 1 1 0 1 1 1 0 FAD binding domain HET PF06985.11 GAP88121.1 - 2.4e-16 60.4 3.9 1.5e-13 51.4 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) CFEM PF05730.11 GAP88122.1 - 7.9e-12 45.1 11.1 1.4e-11 44.3 11.1 1.4 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.16 GAP88123.1 - 8.7e-49 166.3 56.5 1.6e-48 165.5 54.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP88123.1 - 1.1e-17 63.7 26.9 7.5e-17 61.0 26.9 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP88123.1 - 6.9e-13 48.3 9.3 6.9e-13 48.3 9.3 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 GAP88123.1 - 0.00043 18.7 2.2 0.00043 18.7 2.2 2.3 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 GAP88124.1 - 1.3e-74 251.6 0.0 1.6e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PS-DH PF14765.6 GAP88125.1 - 7.5e-63 212.5 0.0 1.2e-62 211.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP88125.1 - 5.1e-59 200.4 0.1 8.1e-59 199.7 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 GAP88125.1 - 1.2e-58 198.0 0.1 2.1e-58 197.2 0.1 1.5 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 GAP88125.1 - 2.3e-51 174.8 0.0 7.1e-51 173.2 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAP88125.1 - 1.9e-29 102.0 0.1 1e-28 99.7 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAP88125.1 - 3.3e-21 75.8 0.0 6.5e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 GAP88125.1 - 3.9e-20 72.5 0.0 9.5e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP88125.1 - 3e-13 50.3 0.0 1.3e-12 48.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 GAP88125.1 - 1.1e-12 49.2 0.0 2.4e-11 44.8 0.0 3.2 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 GAP88125.1 - 3e-11 43.8 0.0 1.5e-10 41.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 GAP88125.1 - 8.1e-11 42.0 0.0 2.3e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 GAP88125.1 - 1.3e-09 38.1 0.0 1.5e-08 34.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain adh_short PF00106.25 GAP88125.1 - 6.3e-09 35.6 0.2 4.4e-08 32.8 0.0 2.5 4 0 0 4 4 4 1 short chain dehydrogenase Methyltransf_31 PF13847.6 GAP88125.1 - 1.8e-08 34.3 0.0 6.2e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 GAP88125.1 - 4e-07 30.3 0.2 1.1e-06 28.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 GAP88125.1 - 3.2e-06 27.0 0.1 7e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.10 GAP88125.1 - 0.0013 18.6 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.9 GAP88125.1 - 0.031 14.0 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase AXE1 PF05448.12 GAP88126.1 - 0.061 12.0 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Zip PF02535.22 GAP88127.1 - 1.2e-52 179.2 0.1 3.6e-52 177.6 0.1 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Cwf_Cwc_15 PF04889.12 GAP88127.1 - 0.021 14.5 1.9 0.033 13.9 1.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DFRP_C PF16543.5 GAP88127.1 - 0.17 12.4 2.3 0.16 12.5 0.8 1.6 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 DUF389 PF04087.14 GAP88127.1 - 1.1 9.3 6.0 6.2 6.8 2.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF389) FtsJ PF01728.19 GAP88129.1 - 5.7e-09 36.3 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase RNA_pol_Rpb1_6 PF04992.14 GAP88129.1 - 0.2 11.4 0.0 0.3 10.9 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Rax2 PF12768.7 GAP88130.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Abhydrolase_6 PF12697.7 GAP88131.1 - 1.6e-19 71.4 0.3 1.9e-19 71.1 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAP88131.1 - 0.00098 18.9 0.1 0.0015 18.3 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 GAP88131.1 - 0.019 14.6 0.1 0.74 9.4 0.3 2.6 2 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP88131.1 - 0.025 13.9 0.1 0.31 10.3 0.1 2.5 2 1 0 2 2 2 0 Serine aminopeptidase, S33 PE-PPE PF08237.11 GAP88131.1 - 0.034 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Lipase_3 PF01764.25 GAP88131.1 - 0.045 13.6 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 GAP88131.1 - 0.054 13.2 0.3 0.25 11.1 0.3 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 GAP88131.1 - 0.12 12.4 0.0 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Oxidored_FMN PF00724.20 GAP88132.1 - 4e-93 312.4 0.0 4.6e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldose_epim PF01263.20 GAP88134.1 - 9.2e-40 136.8 0.0 1.1e-39 136.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase GWT1 PF06423.12 GAP88136.1 - 2.3e-42 144.6 5.7 2.3e-42 144.6 5.7 1.9 2 1 1 3 3 3 1 GWT1 DUF4818 PF16089.5 GAP88136.1 - 0.00045 20.7 0.2 0.0023 18.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4818) DUF5316 PF17247.2 GAP88136.1 - 0.45 10.6 5.7 9 6.4 0.3 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5316) Corona_NS3b PF03053.14 GAP88136.1 - 0.71 9.6 5.4 0.61 9.8 0.7 2.3 2 0 0 2 2 2 0 ORF3b coronavirus protein Peptidase_A4 PF01828.17 GAP88138.1 - 4.3e-76 255.0 13.4 6.8e-76 254.4 13.4 1.3 1 0 0 1 1 1 1 Peptidase A4 family CARDB PF07705.11 GAP88138.1 - 0.031 14.5 1.0 2.1 8.6 0.1 2.6 2 1 0 2 2 2 0 CARDB Rif1_N PF12231.8 GAP88139.1 - 1.6e-142 474.9 1.2 1.6e-142 474.9 1.2 1.5 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.9 GAP88140.1 - 4.4e-126 421.6 0.1 5e-126 421.4 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Chromo PF00385.24 GAP88141.1 - 6.8e-17 61.1 0.1 1.2e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 GAP88141.1 - 0.015 15.2 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain SOG2 PF10428.9 GAP88141.1 - 4 6.5 14.3 4.8 6.3 14.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Rotamase PF00639.21 GAP88141.1 - 6.7 7.7 6.6 17 6.4 0.1 2.7 1 1 2 3 3 3 0 PPIC-type PPIASE domain PQ-loop PF04193.14 GAP88142.1 - 6e-23 80.4 7.0 6.7e-14 51.4 3.6 2.5 2 0 0 2 2 2 2 PQ loop repeat Sulfatase PF00884.23 GAP88143.1 - 1.1e-56 192.6 0.0 1.3e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 GAP88143.1 - 8.6e-24 83.1 0.8 2.1e-23 81.9 0.2 2.0 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 GAP88143.1 - 2.1e-06 27.6 0.0 0.029 13.9 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 GAP88143.1 - 0.1 13.3 0.2 0.42 11.4 0.2 2.0 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 GAP88143.1 - 0.18 11.8 0.0 6.7 6.7 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function Med8 PF10232.9 GAP88144.1 - 4.7e-30 104.9 2.5 7.3e-22 78.1 0.3 2.1 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription complex subunit 8 DUF3243 PF11588.8 GAP88144.1 - 0.039 14.3 0.2 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) Cwf_Cwc_15 PF04889.12 GAP88144.1 - 0.92 9.2 4.0 0.69 9.6 1.6 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BT1 PF03092.16 GAP88146.1 - 0.027 12.7 0.1 0.027 12.7 0.1 1.0 1 0 0 1 1 1 0 BT1 family DUF1494 PF07379.11 GAP88146.1 - 0.33 10.8 1.5 0.44 10.4 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) Acetyltransf_1 PF00583.25 GAP88147.1 - 0.037 14.3 0.0 0.054 13.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family MFS_1 PF07690.16 GAP88148.1 - 4.9e-35 121.1 26.0 4.9e-35 121.1 26.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3671 PF12420.8 GAP88148.1 - 0.12 12.4 6.5 2.2 8.4 2.0 3.6 2 1 0 2 2 2 0 Protein of unknown function GFO_IDH_MocA_C PF02894.17 GAP88149.1 - 7.7e-18 64.6 0.4 3e-17 62.7 0.3 2.0 2 1 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 GAP88149.1 - 4.8e-13 50.0 0.0 9.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_1 PF00175.21 GAP88150.1 - 8.1e-31 106.9 0.0 1.4e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAP88150.1 - 2.9e-22 78.9 0.0 5.3e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAP88150.1 - 2.7e-08 34.1 0.0 0.0002 21.5 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 GAP88150.1 - 0.082 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF155 PF02582.14 GAP88152.1 - 9.8e-56 188.6 0.1 1.7e-55 187.9 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ECSCR PF15820.5 GAP88152.1 - 0.11 12.4 0.6 0.21 11.5 0.6 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator XLF PF09302.11 GAP88153.1 - 1.5e-47 162.1 0.0 2.5e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component TMF_DNA_bd PF12329.8 GAP88153.1 - 5.6 7.0 10.1 1.4 8.9 0.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Forkhead PF00250.18 GAP88154.1 - 1.3e-18 67.0 0.4 2.9e-18 65.9 0.4 1.5 1 0 0 1 1 1 1 Forkhead domain Cactin_mid PF10312.9 GAP88155.1 - 3.5e-60 203.1 3.0 5.3e-60 202.6 3.0 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 GAP88155.1 - 2.3e-58 195.6 4.9 3.7e-58 194.9 4.9 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 GAP88155.1 - 0.029 14.7 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF1087 PF06465.13 GAP88155.1 - 0.13 12.4 0.9 0.63 10.1 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) NYD-SP28_assoc PF14775.6 GAP88155.1 - 0.17 12.0 1.3 11 6.3 0.5 3.1 2 1 0 2 2 2 0 Sperm tail C-terminal domain Glyco_hydro_62 PF03664.13 GAP88156.1 - 3.3e-154 512.0 16.1 3.8e-154 511.8 16.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 p450 PF00067.22 GAP88157.1 - 4.1e-68 230.2 0.0 4.7e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ALF PF03752.13 GAP88157.1 - 0.13 12.2 5.0 0.98 9.4 0.8 2.7 2 0 0 2 2 2 0 Short repeats of unknown function Aldo_ket_red PF00248.21 GAP88158.1 - 2.8e-68 230.3 0.0 5.2e-68 229.4 0.0 1.4 2 0 0 2 2 2 1 Aldo/keto reductase family GST_C_2 PF13410.6 GAP88158.1 - 2.2e-08 34.0 0.0 5.4e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAP88158.1 - 3.3e-08 33.6 0.0 1.1e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAP88158.1 - 8.3e-06 26.1 0.0 1.8e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAP88158.1 - 1.3e-05 25.3 0.0 9.5e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAP88158.1 - 0.00017 21.8 0.0 0.00042 20.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 GAP88158.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAP88158.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 GAP88158.1 - 0.067 13.5 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein NAD_binding_4 PF07993.12 GAP88159.1 - 1.2e-33 116.3 0.0 1.9e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAP88159.1 - 6.3e-17 61.3 0.0 7e-10 38.1 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 GAP88159.1 - 1.5e-14 54.1 0.0 3.9e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAP88159.1 - 6.4e-07 29.6 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 GAP88159.1 - 0.00051 19.5 0.0 0.00091 18.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 GAP88159.1 - 0.0022 17.9 0.0 0.0071 16.3 0.0 1.9 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 GAP88159.1 - 0.015 14.4 0.0 0.11 11.6 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAP88159.1 - 0.031 13.4 0.0 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DIT1_PvcA PF05141.12 GAP88160.1 - 1.9e-82 276.8 0.0 3.5e-82 276.0 0.0 1.4 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 GAP88160.1 - 6.8e-23 81.8 0.1 2.6e-22 79.9 0.1 1.9 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FTA2 PF13095.6 GAP88162.1 - 2.6e-43 148.2 0.0 3.6e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 VasI PF11319.8 GAP88162.1 - 0.21 11.2 1.0 0.46 10.1 0.4 1.9 2 1 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 Slx4 PF09494.10 GAP88163.1 - 9e-23 80.0 0.0 2.7e-22 78.5 0.0 1.9 2 0 0 2 2 2 1 Slx4 endonuclease AT_hook PF02178.19 GAP88163.1 - 0.021 14.7 15.6 0.13 12.3 5.4 3.6 3 0 0 3 3 3 0 AT hook motif Ribosomal_S21e PF01249.18 GAP88164.1 - 1.1e-36 124.8 0.0 1.2e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FAD_binding_7 PF03441.14 GAP88165.1 - 6.1e-79 264.2 0.4 1.3e-78 263.1 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAP88165.1 - 1.8e-41 141.9 0.0 3.2e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 GAP88165.1 - 0.093 13.2 0.0 0.32 11.5 0.0 1.9 1 0 0 1 1 1 0 Universal stress protein family NUDIX PF00293.28 GAP88166.1 - 0.00036 20.6 0.0 0.00069 19.7 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain AF-4 PF05110.13 GAP88166.1 - 8.8 4.3 8.4 12 3.8 8.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NUDIX PF00293.28 GAP88167.1 - 4.8e-22 78.4 0.0 5.7e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 GAP88167.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain Lipase_GDSL_2 PF13472.6 GAP88168.1 - 2e-15 57.6 0.1 4.1e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP88168.1 - 1.6e-07 31.5 0.0 5.1e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 GAP88168.1 - 0.011 15.9 0.5 0.02 15.0 0.0 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family SpoIIIAH PF12685.7 GAP88168.1 - 0.028 14.3 3.8 0.053 13.3 3.8 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein DHDPS PF00701.22 GAP88169.1 - 6.8e-29 100.5 0.0 3.1e-25 88.5 0.0 2.0 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family WD40 PF00400.32 GAP88170.1 - 2.4e-10 40.8 7.0 3.6e-05 24.5 0.6 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP88170.1 - 3.2e-07 30.6 0.0 0.0066 16.7 0.0 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zinc_ribbon_16 PF17034.5 GAP88170.1 - 0.69 10.1 4.8 1.5 9.1 4.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family DUF4379 PF14311.6 GAP88170.1 - 0.8 10.1 6.7 6.7 7.2 1.2 3.0 2 0 0 2 2 2 0 Probable Zinc-ribbon domain zf-CHY PF05495.12 GAP88170.1 - 0.94 10.0 6.2 0.23 12.0 2.7 1.7 1 1 0 1 1 1 0 CHY zinc finger Ribosomal_L37ae PF01780.19 GAP88170.1 - 1.2 9.3 5.2 0.46 10.6 1.3 2.1 2 0 0 2 2 2 0 Ribosomal L37ae protein family zf-TFIIB PF13453.6 GAP88170.1 - 4.2 6.8 6.0 2.1 7.8 2.1 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger MafB19-deam PF14437.6 GAP88171.1 - 1.6e-07 31.2 0.0 2.1e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 GAP88171.1 - 2.6e-06 27.2 0.0 3.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 GAP88171.1 - 1.6 8.8 8.3 2.4 8.2 1.4 2.3 1 1 1 2 2 2 0 Bd3614-like deaminase GMC_oxred_N PF00732.19 GAP88172.1 - 2.3e-25 89.6 0.0 4.3e-25 88.7 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 GAP88172.1 - 0.00022 20.9 2.3 0.25 10.9 0.4 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP88172.1 - 0.002 17.4 0.0 0.033 13.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP88172.1 - 0.0026 17.9 0.1 0.0097 16.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAP88172.1 - 0.0064 15.6 2.2 0.0064 15.6 2.2 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAP88172.1 - 0.0064 15.2 0.2 0.013 14.2 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein GMC_oxred_C PF05199.13 GAP88172.1 - 0.0067 17.0 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_3 PF01494.19 GAP88172.1 - 0.017 14.4 0.3 0.025 13.8 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAP88172.1 - 0.035 13.2 0.1 0.067 12.2 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 GAP88172.1 - 0.071 12.4 0.2 0.13 11.5 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 GAP88172.1 - 0.099 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 GAP88172.1 - 0.12 11.4 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF2277 PF10041.9 GAP88173.1 - 0.022 15.1 0.1 0.062 13.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) PPDFL PF15060.6 GAP88173.1 - 0.031 14.8 0.0 0.072 13.6 0.0 1.6 1 0 0 1 1 1 0 Differentiation and proliferation regulator JAB PF01398.21 GAP88174.1 - 1.2e-27 96.2 0.0 2.5e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 GAP88174.1 - 1.2e-10 41.8 0.5 2e-10 41.0 0.5 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 GAP88174.1 - 2.4e-06 27.3 0.0 5.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain NPR1_interact PF15699.5 GAP88174.1 - 0.052 14.2 1.3 0.067 13.8 0.2 1.7 1 1 1 2 2 2 0 NPR1 interacting DEAD PF00270.29 GAP88175.1 - 5.3e-26 91.4 0.3 5.8e-25 88.1 0.3 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP88175.1 - 1e-22 80.6 0.0 8.1e-22 77.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP88175.1 - 5.4e-06 26.5 1.1 3.6e-05 23.8 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 GAP88175.1 - 0.033 13.0 0.3 0.26 10.0 0.0 2.1 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Sld7_C PF18596.1 GAP88175.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Sld7 C-terminal domain Acetyltransf_1 PF00583.25 GAP88177.1 - 0.00019 21.6 0.0 0.00043 20.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family KorB_C PF06613.11 GAP88177.1 - 0.085 12.8 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain EthD PF07110.11 GAP88179.1 - 4.6e-18 66.2 0.8 5.5e-18 65.9 0.8 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 GAP88179.1 - 0.04 14.4 0.1 0.13 12.7 0.1 1.7 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase FAD-oxidase_C PF02913.19 GAP88180.1 - 1.6e-60 204.8 0.1 3.4e-60 203.8 0.1 1.6 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAP88180.1 - 3.3e-36 124.1 0.0 6.9e-36 123.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain DUF1995 PF09353.10 GAP88180.1 - 0.047 13.7 0.1 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1995) BUD22 PF09073.10 GAP88181.1 - 4.6e-05 23.0 7.1 5.3e-05 22.7 7.1 1.0 1 0 0 1 1 1 1 BUD22 RNA_pol_Rpc4 PF05132.14 GAP88181.1 - 0.0071 16.8 1.9 0.009 16.5 1.9 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 Presenilin PF01080.17 GAP88181.1 - 0.058 12.2 0.2 0.058 12.2 0.2 1.1 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 GAP88181.1 - 0.086 12.0 8.9 0.091 12.0 8.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mem_trans PF03547.18 GAP88181.1 - 0.17 10.3 0.6 0.24 9.8 0.6 1.2 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.14 GAP88181.1 - 0.61 8.3 7.1 0.75 8.0 7.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4614 PF15391.6 GAP88181.1 - 0.85 9.6 9.9 1.3 9.0 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 GAP88181.1 - 0.88 8.3 8.1 1.1 8.0 8.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain NST1 PF13945.6 GAP88181.1 - 1.7 8.7 7.9 2.3 8.3 7.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator RAP1 PF07218.11 GAP88181.1 - 2.6 6.2 4.4 3.2 5.9 4.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Rtf2 PF04641.12 GAP88181.1 - 2.7 7.3 9.8 3.6 6.9 9.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger XAP5 PF04921.14 GAP88181.1 - 3.1 7.6 10.2 4.1 7.2 10.2 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator CPSF100_C PF13299.6 GAP88181.1 - 4 7.6 6.3 5.4 7.2 6.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Tyrosinase PF00264.20 GAP88182.1 - 6.4e-46 157.4 0.0 9.1e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.16 GAP88183.1 - 1.9e-29 102.7 27.7 1.9e-29 102.7 27.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Helo_like_N PF17111.5 GAP88185.1 - 2.7e-06 26.9 0.0 4.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins TraA PF05513.11 GAP88186.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 TraA SprT-like PF10263.9 GAP88188.1 - 4e-16 58.9 0.0 7.3e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 SprT-like family DUF730 PF05325.11 GAP88188.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF730) Pkinase_fungal PF17667.1 GAP88189.1 - 0.00011 21.2 0.0 0.00013 20.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase zf-RING_2 PF13639.6 GAP88190.1 - 8.1e-12 45.3 6.6 1.3e-11 44.7 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAP88190.1 - 6.3e-08 32.3 6.4 1e-07 31.7 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP88190.1 - 1.3e-07 31.4 4.1 2.1e-07 30.7 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAP88190.1 - 1.3e-07 31.2 0.9 2.3e-07 30.4 0.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAP88190.1 - 4e-06 27.0 9.3 1.8e-05 24.9 9.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAP88190.1 - 5.4e-06 26.3 3.8 8.5e-06 25.6 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 GAP88190.1 - 0.001 19.1 0.9 0.001 19.1 0.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAP88190.1 - 0.0022 18.0 1.8 0.0042 17.1 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 GAP88190.1 - 0.0025 17.6 2.6 0.0039 17.0 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 GAP88190.1 - 0.0073 16.1 6.7 0.013 15.3 6.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PanZ PF12568.8 GAP88190.1 - 0.044 13.5 0.1 0.088 12.5 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Prok-RING_4 PF14447.6 GAP88190.1 - 0.086 12.7 4.4 0.19 11.6 4.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 GAP88190.1 - 0.13 12.4 3.1 0.33 11.1 3.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-UDP PF14569.6 GAP88190.1 - 0.17 12.1 0.8 0.48 10.6 0.8 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 GAP88190.1 - 0.2 11.3 4.7 0.35 10.5 4.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 GAP88190.1 - 0.25 11.3 5.8 0.45 10.4 5.8 1.4 1 0 0 1 1 1 0 PHD-finger OAD_gamma PF04277.13 GAP88190.1 - 0.76 10.4 0.0 0.76 10.4 0.0 3.5 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Hamartin PF04388.12 GAP88190.1 - 1.1 7.9 4.9 1.8 7.1 4.9 1.3 1 0 0 1 1 1 0 Hamartin protein zf-C3HC4_4 PF15227.6 GAP88190.1 - 1.2 9.3 4.4 2.5 8.3 4.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 GAP88190.1 - 3.3 7.9 5.6 6.9 6.9 5.6 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 GAP88190.1 - 4.8 7.2 8.2 0.2 11.6 1.3 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3752 PF12572.8 GAP88191.1 - 4.1e-48 163.8 7.8 4.1e-48 163.8 7.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) RhoGEF67_u1 PF16615.5 GAP88191.1 - 0.032 14.7 0.3 0.16 12.5 0.3 2.3 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 2OG-FeII_Oxy_2 PF13532.6 GAP88192.1 - 6.9e-12 46.0 0.0 1.3e-11 45.0 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Atrophin-1 PF03154.15 GAP88192.1 - 2.2 6.5 6.3 3.2 5.9 6.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family PIG-P PF08510.12 GAP88193.1 - 1.3e-53 180.1 1.6 1.6e-53 179.7 1.6 1.1 1 0 0 1 1 1 1 PIG-P Rab5ip PF07019.12 GAP88193.1 - 0.19 12.4 4.4 0.3 11.7 4.4 1.4 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Phage_holin_3_6 PF07332.11 GAP88193.1 - 0.78 9.8 2.6 1.4 9.0 2.6 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DPM2 PF07297.12 GAP88193.1 - 4.6 7.6 12.8 8.7 6.7 12.5 1.6 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Dala_Dala_lig_C PF07478.13 GAP88194.1 - 1.5e-09 37.7 0.0 2.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 GAP88194.1 - 7.2e-05 22.9 0.0 0.0001 22.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 GAP88194.1 - 0.0012 18.5 0.0 0.0057 16.3 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 GAP88194.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 GAP88194.1 - 0.024 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 GAP88194.1 - 0.039 13.5 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain p450 PF00067.22 GAP88195.1 - 2.9e-43 148.3 0.0 1.7e-42 145.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_7 PF13508.7 GAP88196.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP88196.1 - 0.074 13.3 0.0 0.32 11.2 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family PAF-AH_p_II PF03403.13 GAP88197.1 - 2.5e-08 32.9 0.1 4.2e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 GAP88197.1 - 2.3e-05 24.2 0.0 0.00028 20.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 GAP88197.1 - 0.0011 17.9 0.2 0.0035 16.3 0.2 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 GAP88197.1 - 0.0039 16.5 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 GAP88197.1 - 0.062 13.1 0.0 8.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 GAP88197.1 - 0.12 13.0 1.6 0.14 12.8 0.3 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 GAP88197.1 - 0.19 10.7 0.3 0.59 9.1 0.3 1.7 1 1 0 1 1 1 0 Chlorophyllase HET PF06985.11 GAP88199.1 - 3.6e-24 85.8 0.4 3.6e-24 85.8 0.4 2.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Trypan_PARP PF05887.11 GAP88199.1 - 1.1 9.3 29.3 4.6 7.2 9.6 2.3 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) BUD22 PF09073.10 GAP88199.1 - 4 6.7 34.6 5.5 6.2 34.6 1.1 1 0 0 1 1 1 0 BUD22 Peptidase_M28 PF04389.17 GAP88200.1 - 9.3e-25 87.5 0.0 1.2e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Ribophorin_II PF05817.14 GAP88201.1 - 1.2e-26 93.5 0.0 1.6e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PufQ PF05398.11 GAP88201.1 - 0.16 12.1 3.1 0.15 12.2 1.3 1.9 1 1 1 2 2 2 0 PufQ cytochrome subunit CDP-OH_P_transf PF01066.21 GAP88202.1 - 3.2e-16 59.9 0.4 3.2e-16 59.9 0.4 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.25 GAP88204.1 - 1.2e-18 67.5 0.0 2.3e-18 66.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP88204.1 - 6.5e-11 42.0 0.0 2e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAP88205.1 - 1.2e-23 83.8 0.0 7.3e-18 64.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain HET PF06985.11 GAP88205.1 - 7.6e-23 81.5 0.0 1.7e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.17 GAP88205.1 - 3.2e-16 59.4 0.0 2.4e-15 56.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP88205.1 - 0.033 14.1 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_3_C PF01915.22 GAP88206.1 - 2.7e-37 128.7 0.0 8.6e-37 127.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAP88206.1 - 4.4e-29 101.8 0.0 6.2e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAP88206.1 - 1.3e-06 28.5 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain HET PF06985.11 GAP88207.1 - 7.8e-34 117.1 0.0 1.5e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAM76 PF16046.5 GAP88209.1 - 0.00059 19.3 9.5 0.0011 18.4 9.5 1.5 1 0 0 1 1 1 1 FAM76 protein Spc7 PF08317.11 GAP88209.1 - 0.0071 15.3 14.3 0.014 14.3 14.3 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.21 GAP88209.1 - 0.01 15.4 10.3 0.01 15.4 10.3 1.6 2 0 0 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 GAP88209.1 - 0.014 15.4 15.1 0.14 12.2 15.2 2.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.14 GAP88209.1 - 0.034 14.5 13.2 0.28 11.5 13.2 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Rab5-bind PF09311.11 GAP88209.1 - 0.036 13.5 15.0 0.13 11.6 1.4 2.7 1 1 1 2 2 2 0 Rabaptin-like protein Sec2p PF06428.11 GAP88209.1 - 0.045 13.7 11.9 1.1 9.3 0.7 3.4 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p GAIN PF16489.5 GAP88209.1 - 0.059 12.8 5.3 0.25 10.7 5.3 1.9 1 1 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain DUF4686 PF15742.5 GAP88209.1 - 0.063 12.4 16.2 0.15 11.2 16.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Phage_GP20 PF06810.11 GAP88209.1 - 0.081 12.7 20.6 0.82 9.5 11.9 3.5 1 1 2 3 3 3 0 Phage minor structural protein GP20 Atg14 PF10186.9 GAP88209.1 - 0.087 11.9 16.1 0.29 10.2 8.8 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 GAP88209.1 - 0.12 12.7 11.0 0.12 12.7 5.1 3.2 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3138 PF11336.8 GAP88209.1 - 0.16 10.6 1.0 0.21 10.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) AAA_13 PF13166.6 GAP88209.1 - 0.18 10.4 13.5 0.73 8.4 13.2 1.9 1 1 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.7 GAP88209.1 - 0.2 11.8 23.9 0.044 13.9 16.0 2.6 2 1 1 3 3 2 0 Tropomyosin like Nsp1_C PF05064.13 GAP88209.1 - 0.24 11.2 5.8 0.61 9.9 2.6 2.6 2 1 0 2 2 2 0 Nsp1-like C-terminal region DUF4407 PF14362.6 GAP88209.1 - 0.25 10.6 16.0 0.47 9.7 16.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 GAP88209.1 - 0.42 10.7 19.7 0.032 14.3 8.1 2.9 2 1 0 3 3 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 GAP88209.1 - 0.62 10.3 23.8 0.14 12.4 18.4 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 GAP88209.1 - 0.65 10.5 19.1 0.68 10.5 14.7 2.8 2 1 1 3 3 3 0 Apg6 coiled-coil region Sec8_exocyst PF04048.14 GAP88209.1 - 0.72 9.7 11.8 2.9 7.8 0.3 3.1 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain DUF16 PF01519.16 GAP88209.1 - 0.99 9.9 11.1 1.2 9.6 7.5 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 KASH_CCD PF14662.6 GAP88209.1 - 1.1 9.1 15.6 0.072 12.9 7.6 2.6 2 1 1 3 3 2 0 Coiled-coil region of CCDC155 or KASH Prominin PF05478.11 GAP88209.1 - 1.1 7.1 4.4 1.7 6.5 4.4 1.3 1 0 0 1 1 1 0 Prominin DivIC PF04977.15 GAP88209.1 - 1.1 9.0 10.9 2.9 7.7 4.5 3.5 2 1 1 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.19 GAP88209.1 - 1.9 6.3 8.2 4.8 5.0 8.3 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Lebercilin PF15619.6 GAP88209.1 - 2.4 7.8 19.9 0.46 10.1 4.0 3.5 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease CREPT PF16566.5 GAP88209.1 - 2.6 8.2 9.5 3.7 7.7 7.8 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF848 PF05852.11 GAP88209.1 - 3.7 7.6 12.8 5.5 7.1 7.3 2.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1664 PF07889.12 GAP88209.1 - 4.8 7.2 12.5 11 6.1 4.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 GAP88209.1 - 6.9 7.2 9.5 61 4.2 4.3 3.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.9 GAP88209.1 - 9.5 7.0 10.6 8 7.2 4.6 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 GAP88209.1 - 10 5.3 10.4 14 4.8 9.1 1.9 1 1 1 2 2 2 0 TMPIT-like protein ABC_tran PF00005.27 GAP88211.1 - 7e-50 169.1 0.0 8.7e-30 104.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAP88211.1 - 1.2e-36 126.8 28.0 4.4e-24 85.6 13.9 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 GAP88211.1 - 3.1e-09 36.6 0.1 0.0029 17.1 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 GAP88211.1 - 0.00032 19.8 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 GAP88211.1 - 0.00048 19.8 0.7 0.55 10.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAP88211.1 - 0.0022 18.0 0.2 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP88211.1 - 0.0024 17.8 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 GAP88211.1 - 0.0088 16.3 0.2 29 4.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 GAP88211.1 - 0.012 15.2 0.0 1.9 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAP88211.1 - 0.027 14.2 0.0 1 9.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_16 PF13191.6 GAP88211.1 - 0.055 13.9 4.8 0.81 10.0 0.0 3.3 4 0 0 4 4 3 0 AAA ATPase domain SbcCD_C PF13558.6 GAP88211.1 - 0.097 12.9 0.1 56 4.1 0.0 3.6 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 GAP88211.1 - 0.1 12.7 7.3 0.39 10.8 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_10 PF12846.7 GAP88211.1 - 0.15 10.9 0.5 2 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_21 PF13304.6 GAP88211.1 - 0.23 11.2 1.8 9.3 5.9 0.3 3.4 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 GAP88211.1 - 1.1 9.0 3.0 11 5.7 0.1 3.2 4 0 0 4 4 4 0 AAA domain WD40 PF00400.32 GAP88212.1 - 4.4e-18 65.3 8.2 0.0048 17.7 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP88212.1 - 1.6e-13 50.7 0.0 0.00077 19.7 0.0 5.0 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAP88212.1 - 0.00076 19.4 0.1 0.14 12.0 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 GAP88212.1 - 0.084 12.8 1.8 7.5 6.6 0.3 4.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ank_2 PF12796.7 GAP88213.1 - 1.9e-47 159.8 0.4 1.9e-15 57.2 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88213.1 - 3.8e-31 107.1 0.0 1.1e-07 32.3 0.0 7.1 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88213.1 - 2e-28 95.3 0.0 0.0016 18.8 0.0 8.8 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 GAP88213.1 - 2e-26 91.2 2.2 0.04 14.4 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 GAP88213.1 - 3.9e-10 39.8 2.6 0.65 10.4 0.1 6.7 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Peptidase_M14 PF00246.24 GAP88214.1 - 4e-46 158.1 2.2 5.6e-46 157.7 2.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Pkinase PF00069.25 GAP88215.1 - 2.3e-08 33.7 0.0 3.8e-06 26.5 0.0 3.7 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP88215.1 - 5e-07 29.3 0.4 0.0032 16.8 0.2 4.0 3 1 0 3 3 3 3 Protein tyrosine kinase Ank_2 PF12796.7 GAP88216.1 - 2.2e-43 146.7 5.1 9.1e-11 42.2 0.1 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 GAP88216.1 - 2.4e-30 103.6 15.8 9.5e-05 22.7 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 GAP88216.1 - 9.9e-27 92.7 10.0 5.4e-05 23.4 0.0 8.3 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAP88216.1 - 2.3e-25 88.6 4.9 4.6e-06 27.1 0.0 7.7 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88216.1 - 6e-25 84.6 4.2 0.0057 17.1 0.0 9.8 10 0 0 10 10 10 5 Ankyrin repeat GATase_7 PF13537.6 GAP88216.1 - 0.016 15.1 0.0 12 5.9 0.0 4.5 5 2 2 7 7 7 0 Glutamine amidotransferase domain FAD_binding_4 PF01565.23 GAP88217.1 - 9.1e-22 77.3 0.1 1.3e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP88217.1 - 0.00051 20.1 0.3 0.0011 19.1 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 GAP88218.1 - 4.1e-47 161.0 0.0 7.8e-47 160.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PRR22 PF15776.5 GAP88218.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Proline-rich protein family 22 adh_short PF00106.25 GAP88219.1 - 8.6e-19 67.8 0.0 4.2e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88219.1 - 5.9e-08 32.6 0.0 5e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88219.1 - 7.7e-07 29.2 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 GAP88219.1 - 0.028 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus SseB PF07179.12 GAP88219.1 - 0.042 14.1 0.0 0.13 12.5 0.0 2.0 1 1 0 1 1 1 0 SseB protein N-terminal domain Polysacc_synt_2 PF02719.15 GAP88219.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Tubulin_3 PF14881.6 GAP88219.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain adh_short PF00106.25 GAP88220.1 - 1.7e-21 76.6 0.0 2.3e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88220.1 - 9.5e-12 45.0 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAP88220.1 - 0.001 18.6 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 GAP88220.1 - 0.0051 16.7 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Lactococcin PF04369.13 GAP88220.1 - 0.012 15.7 0.2 0.26 11.4 0.0 2.7 3 0 0 3 3 3 0 Lactococcin-like family FAD_binding_4 PF01565.23 GAP88221.1 - 6e-22 77.9 1.4 1.5e-21 76.6 1.4 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP88221.1 - 0.02 15.0 0.1 0.043 13.9 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like CDC73_C PF05179.14 GAP88221.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal Fungal_trans_2 PF11951.8 GAP88222.1 - 3.3e-30 105.2 6.4 2.8e-29 102.1 6.4 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Trp_DMAT PF11991.8 GAP88223.1 - 1.9e-80 271.0 0.0 2.3e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Cupin_2 PF07883.11 GAP88224.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain ketoacyl-synt PF00109.26 GAP88225.1 - 1.7e-58 198.2 0.0 4.3e-58 196.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP88225.1 - 2.5e-54 183.9 0.0 5.9e-54 182.7 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 GAP88225.1 - 2.8e-52 177.8 0.0 4.8e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP88225.1 - 1.1e-49 169.7 0.1 1.8e-49 169.0 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP88225.1 - 7.4e-37 126.0 0.0 2e-36 124.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAP88225.1 - 9.5e-18 64.7 0.1 2.4e-17 63.4 0.1 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 GAP88225.1 - 3.2e-13 49.8 0.0 1.1e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAP88225.1 - 1.2e-10 41.2 0.0 5.4e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 GAP88225.1 - 5.1e-10 40.5 0.1 1.9e-09 38.7 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 GAP88225.1 - 7.4e-07 29.0 0.1 4.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 GAP88225.1 - 0.00017 21.4 0.0 0.00046 20.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 GAP88225.1 - 0.002 17.6 0.2 0.0043 16.5 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 GAP88225.1 - 0.043 13.7 0.2 0.12 12.2 0.2 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short_C2 PF13561.6 GAP88226.1 - 1e-53 182.3 1.2 2.7e-53 181.0 1.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP88226.1 - 4.2e-41 140.5 0.8 8.3e-41 139.6 0.8 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP88226.1 - 1.1e-07 32.0 0.2 2e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 KR domain Cupin_2 PF07883.11 GAP88227.1 - 6.8e-06 25.7 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Cupin domain FAD_binding_4 PF01565.23 GAP88228.1 - 4.7e-23 81.5 1.1 9.3e-23 80.5 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP88228.1 - 1.1e-08 35.0 0.1 2.9e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 GAP88229.1 - 7.9e-31 107.0 0.0 1e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88229.1 - 3.2e-24 85.8 0.0 3.9e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88229.1 - 1.3e-07 31.8 0.0 1.8e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP88229.1 - 0.002 17.6 0.1 0.004 16.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP88229.1 - 0.0027 17.6 0.1 0.0049 16.8 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 GAP88229.1 - 0.047 13.1 0.3 0.28 10.5 0.3 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 GAP88230.1 - 1.3e-14 53.9 0.5 2.1e-14 53.2 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.11 GAP88231.1 - 4.8e-06 26.2 0.0 8.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.25 GAP88232.1 - 4e-38 130.8 0.0 4.8e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88232.1 - 3.5e-29 102.0 0.0 4.5e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAP88232.1 - 0.00024 20.7 0.1 0.00034 20.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 GAP88232.1 - 0.012 15.6 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 GAP88232.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAP88232.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_3 PF03447.16 GAP88232.1 - 0.062 14.0 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain p450 PF00067.22 GAP88233.1 - 6.1e-70 236.3 0.0 7.6e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sulfatase PF00884.23 GAP88235.1 - 9.7e-76 255.1 0.0 1.2e-75 254.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 GAP88235.1 - 0.0075 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function Sugar_tr PF00083.24 GAP88236.1 - 6.1e-89 298.9 21.1 7.8e-89 298.6 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_43 PF04616.14 GAP88236.1 - 6.1e-43 147.2 5.1 1.1e-41 143.0 5.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 MFS_1 PF07690.16 GAP88236.1 - 1.8e-13 50.2 21.3 1.8e-13 50.2 21.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily GH43_C2 PF17851.1 GAP88236.1 - 2.7e-13 50.1 0.0 1.2e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Beta xylosidase C-terminal Concanavalin A-like domain MFS_2 PF13347.6 GAP88236.1 - 4.2e-06 25.6 2.1 4.2e-06 25.6 2.1 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein Glyco_hydro_16 PF00722.21 GAP88237.1 - 9.4e-14 51.3 0.3 1.7e-13 50.4 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 GAP88237.1 - 3.2e-05 22.5 0.7 0.067 11.6 0.1 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) GspH PF12019.8 GAP88237.1 - 0.84 10.1 5.2 0.25 11.8 0.7 2.1 2 0 0 2 2 2 0 Type II transport protein GspH TRAUB PF08164.12 GAP88238.1 - 2.3e-25 88.9 0.0 2.3e-25 88.9 0.0 3.0 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 GAP88238.1 - 1.3e-21 77.8 6.0 1.3e-21 77.8 6.0 2.5 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor ParA PF10609.9 GAP88239.1 - 4e-94 314.7 0.1 4.6e-94 314.5 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAP88239.1 - 2.7e-11 43.6 0.0 4.7e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAP88239.1 - 1.6e-09 37.9 0.2 1.4e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 GAP88239.1 - 4.8e-06 26.0 0.2 9.7e-05 21.7 0.1 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 GAP88239.1 - 1.1e-05 24.9 0.0 3.1e-05 23.4 0.0 1.8 2 1 0 2 2 2 1 ATPase MipZ Fer4_NifH PF00142.18 GAP88239.1 - 0.00016 21.2 0.0 0.022 14.2 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 GAP88239.1 - 0.002 17.7 0.3 0.037 13.5 0.2 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 GAP88239.1 - 0.0023 17.5 0.2 0.0082 15.7 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.6 GAP88239.1 - 0.0032 17.3 0.4 1 9.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain CLP1_P PF16575.5 GAP88239.1 - 0.032 14.0 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 GAP88239.1 - 0.11 11.4 0.2 0.11 11.4 0.2 1.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Tudor_3 PF18115.1 GAP88240.1 - 1.2e-06 28.3 0.1 1.8e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 GAP88240.1 - 0.0029 17.6 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 GAP88240.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain CCDC-167 PF15188.6 GAP88240.1 - 0.038 14.3 0.2 0.076 13.4 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF1325 PF07039.11 GAP88240.1 - 0.084 13.0 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 SGF29 tudor-like domain Mito_fiss_reg PF05308.11 GAP88240.1 - 0.57 10.2 13.9 1.4 8.9 2.6 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Arf PF00025.21 GAP88241.1 - 2.6e-21 75.8 0.1 5.2e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAP88241.1 - 6.9e-05 22.3 0.1 0.00012 21.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 GAP88241.1 - 0.0013 19.0 0.1 0.0027 17.9 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 GAP88241.1 - 0.006 15.8 0.2 0.051 12.7 0.2 2.1 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 GAP88241.1 - 0.089 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Ras PF00071.22 GAP88241.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Ras family zf-C2H2 PF00096.26 GAP88242.1 - 0.0017 18.7 2.9 0.0017 18.7 2.9 5.3 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GAP88242.1 - 0.095 13.0 3.4 14 6.1 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP88242.1 - 0.33 11.4 0.2 0.33 11.4 0.2 3.3 3 1 0 3 3 3 0 Zinc-finger of C2H2 type DUF1272 PF06906.11 GAP88242.1 - 5.2 7.2 7.9 3.9 7.6 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.6 GAP88242.1 - 7.4 6.1 7.5 36 4.0 0.3 4.2 3 1 1 4 4 4 0 zinc-ribbon domain Ank_2 PF12796.7 GAP88244.1 - 2.8e-20 72.7 0.0 1.5e-10 41.6 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88244.1 - 3.2e-11 43.5 0.0 0.00012 22.6 0.0 4.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88244.1 - 3.2e-11 42.4 0.4 0.085 13.5 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 GAP88244.1 - 3.4e-10 40.0 0.4 0.015 15.6 0.1 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 GAP88244.1 - 8.1e-08 32.4 0.1 0.11 13.0 0.0 4.3 3 1 0 3 3 3 2 Ankyrin repeat F-box-like PF12937.7 GAP88244.1 - 0.0022 17.9 0.3 0.012 15.5 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAP88244.1 - 0.092 12.7 1.9 0.5 10.3 1.9 2.3 1 1 0 1 1 1 0 F-box domain UQ_con PF00179.26 GAP88246.1 - 4.6e-35 120.3 0.1 5.3e-35 120.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF572 PF04502.13 GAP88247.1 - 5e-68 230.2 0.0 5.9e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) SesA PF17107.5 GAP88248.1 - 0.0041 17.3 0.1 0.01 16.0 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases CMV_1a PF12467.8 GAP88248.1 - 0.019 15.3 3.0 0.02 15.2 1.2 1.9 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Rx_N PF18052.1 GAP88248.1 - 0.037 14.3 0.7 1.8 8.9 0.1 3.0 3 1 0 3 3 3 0 Rx N-terminal domain Nnf1 PF03980.14 GAP88248.1 - 0.29 11.5 1.6 3.2 8.2 0.2 2.5 2 0 0 2 2 2 0 Nnf1 VWA_3 PF13768.6 GAP88249.1 - 1.5e-26 93.2 0.0 2.8e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 GAP88249.1 - 1.9e-25 89.2 0.0 3.6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 GAP88249.1 - 2.8e-09 37.5 0.0 5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 GAP88249.1 - 6.1e-09 35.6 0.0 1.6e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 GAP88249.1 - 3.6e-07 30.8 0.0 1.1e-06 29.3 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 GAP88249.1 - 0.00016 21.1 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Hemerythrin PF01814.23 GAP88250.1 - 6.2e-06 26.9 0.0 8.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GFA PF04828.14 GAP88251.1 - 4.3e-12 46.2 0.0 5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Tgi2PP PF18250.1 GAP88251.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Effector immunity protein Tgi2PP Zn_ribbon_recom PF13408.6 GAP88251.1 - 0.13 12.8 0.1 0.2 12.2 0.1 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Glyco_hydro_72 PF03198.14 GAP88252.1 - 1.7e-111 372.5 3.6 2.3e-111 372.1 3.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 GAP88252.1 - 4.7e-19 68.9 4.6 1.3e-18 67.4 4.6 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_36 PF17167.4 GAP88253.1 - 3.1e-59 200.8 0.0 6.1e-59 199.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 GAP88253.1 - 3e-23 82.5 0.0 5e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 Phe_ZIP PF08916.11 GAP88253.1 - 0.012 16.3 0.7 0.033 14.9 0.7 1.8 1 0 0 1 1 1 0 Phenylalanine zipper Vac7 PF12751.7 GAP88253.1 - 2 7.8 10.4 2.9 7.2 10.4 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Zip PF02535.22 GAP88253.1 - 9 5.4 6.6 16 4.6 6.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_7 PF00840.20 GAP88255.1 - 2.4e-73 247.3 0.0 2.7e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.20 GAP88256.1 - 4.7e-59 200.2 0.6 5.6e-59 200.0 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FAD_binding_3 PF01494.19 GAP88257.1 - 2.8e-66 224.1 0.0 2.7e-60 204.4 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain MFS_1 PF07690.16 GAP88257.1 - 2.2e-32 112.3 25.8 7.4e-32 110.6 25.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAP88257.1 - 6.4e-06 25.7 3.2 1.3e-05 24.6 3.2 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF4668 PF15701.5 GAP88257.1 - 0.2 11.5 0.7 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4668) Amidohydro_1 PF01979.20 GAP88258.1 - 5.3e-06 26.0 0.0 5.8e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAP88258.1 - 0.014 14.9 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family Fungal_trans PF04082.18 GAP88259.1 - 0.034 13.2 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2985 PF11204.8 GAP88262.1 - 6.8e-20 71.0 6.0 1.2e-19 70.2 6.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Phage_holin_3_6 PF07332.11 GAP88262.1 - 0.00079 19.4 1.5 0.2 11.7 0.3 2.3 2 0 0 2 2 2 2 Putative Actinobacterial Holin-X, holin superfamily III MMR_HSR1 PF01926.23 GAP88263.1 - 2.9e-10 40.2 1.5 3.5e-10 40.0 0.2 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAP88263.1 - 5.7e-07 29.1 0.1 5.7e-07 29.1 0.1 1.7 2 0 0 2 2 2 1 AIG1 family Septin PF00735.18 GAP88263.1 - 0.00014 21.2 0.1 0.00024 20.5 0.1 1.3 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 GAP88263.1 - 0.00069 19.2 0.3 0.0018 17.8 0.3 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 GAP88263.1 - 0.0032 17.4 0.5 0.0032 17.4 0.5 2.0 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 GAP88263.1 - 0.0053 16.8 4.9 0.45 10.6 0.3 3.1 2 1 1 3 3 3 2 Dynamin family NB-ARC PF00931.22 GAP88263.1 - 0.0095 15.1 0.1 0.02 14.1 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 GAP88263.1 - 0.029 14.7 0.2 0.084 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAP88263.1 - 0.032 14.7 1.4 0.085 13.4 1.3 2.0 1 1 0 1 1 1 0 ABC transporter IIGP PF05049.13 GAP88263.1 - 0.047 12.7 1.1 1.5 7.8 0.1 2.2 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF883 PF05957.13 GAP88263.1 - 0.072 13.7 4.1 0.13 12.8 4.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) AAA_30 PF13604.6 GAP88263.1 - 0.086 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 GAP88263.1 - 0.092 12.5 0.5 0.092 12.5 0.5 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 GAP88263.1 - 0.1 12.5 0.7 8.3 6.2 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Pox_A_type_inc PF04508.12 GAP88263.1 - 0.14 12.0 2.9 2.1 8.4 0.7 3.1 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat cobW PF02492.19 GAP88263.1 - 0.15 11.7 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 GAP88263.1 - 0.15 11.6 0.2 0.15 11.6 0.2 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Kinesin PF00225.23 GAP88263.1 - 0.21 10.5 1.9 0.17 10.8 0.1 1.6 2 0 0 2 2 2 0 Kinesin motor domain AAA_18 PF13238.6 GAP88263.1 - 0.34 11.5 2.2 0.71 10.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAP88263.1 - 1.3 9.2 4.9 0.53 10.4 1.0 2.4 2 1 0 2 2 2 0 AAA domain Cupin_8 PF13621.6 GAP88264.1 - 8.6e-25 87.9 0.0 1.1e-24 87.6 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAP88264.1 - 8.2e-05 22.2 0.5 0.0016 18.0 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 GAP88264.1 - 0.001 19.5 0.0 0.0024 18.3 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 GAP88264.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Cupin domain CK_II_beta PF01214.18 GAP88265.1 - 4.6e-75 251.4 0.0 8.3e-75 250.6 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 GAP88265.1 - 0.13 10.8 2.4 0.19 10.2 2.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 GAP88265.1 - 2.7 7.7 5.5 3.3 7.4 2.4 2.0 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 GAP88265.1 - 2.7 8.4 11.7 3 8.3 4.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC2_membrane PF01061.24 GAP88266.1 - 1e-76 257.0 61.8 1e-39 136.2 22.0 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 GAP88266.1 - 5.1e-36 124.2 0.0 1.9e-17 64.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAP88266.1 - 1.1e-31 108.6 1.4 3.7e-24 84.4 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 GAP88266.1 - 1.1e-17 64.3 0.0 4.7e-17 62.4 0.0 2.2 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 GAP88266.1 - 5.2e-06 26.5 0.0 0.14 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 GAP88266.1 - 7.9e-06 26.4 0.2 0.037 14.4 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 GAP88266.1 - 3.3e-05 24.1 0.0 0.014 15.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAP88266.1 - 7e-05 23.4 0.0 0.0076 16.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAP88266.1 - 0.00012 21.7 0.1 0.013 15.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 GAP88266.1 - 0.00021 20.9 0.1 0.038 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GAP88266.1 - 0.00033 21.1 0.1 0.027 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 GAP88266.1 - 0.00049 20.4 0.1 0.15 12.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 GAP88266.1 - 0.00051 20.0 0.0 0.003 17.5 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 GAP88266.1 - 0.00059 19.0 44.7 0.0059 15.8 20.9 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein NACHT PF05729.12 GAP88266.1 - 0.0027 17.6 0.4 2.2 8.2 0.0 2.4 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.19 GAP88266.1 - 0.0049 16.3 0.1 0.54 9.7 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 GAP88266.1 - 0.0067 16.0 0.7 0.23 11.1 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 GAP88266.1 - 0.0071 16.6 0.0 0.68 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAP88266.1 - 0.011 16.2 0.1 6 7.3 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAP88266.1 - 0.017 14.8 0.1 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 GAP88266.1 - 0.019 14.3 0.0 0.42 9.9 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_19 PF13245.6 GAP88266.1 - 0.057 13.8 0.0 2.5 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAP88266.1 - 0.093 13.1 0.5 73 3.8 0.0 3.6 3 0 0 3 3 3 0 RNA helicase AAA_23 PF13476.6 GAP88266.1 - 0.11 13.0 0.3 0.56 10.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAP88266.1 - 0.11 12.5 0.2 6.7 6.7 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 GAP88266.1 - 0.12 12.2 0.1 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Wzz PF02706.15 GAP88266.1 - 0.22 11.8 1.0 1.9 8.8 0.0 3.1 3 0 0 3 3 2 0 Chain length determinant protein B_lectin PF01453.24 GAP88267.1 - 2.9e-05 24.5 0.3 0.00057 20.4 0.1 2.1 1 1 1 2 2 2 2 D-mannose binding lectin ATG19_autophagy PF12744.7 GAP88267.1 - 0.045 12.9 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding Peroxidase_2 PF01328.17 GAP88269.1 - 8.7e-50 169.9 0.0 1e-49 169.6 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Zn_clus PF00172.18 GAP88270.1 - 6e-08 32.7 9.0 1e-07 32.0 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.8 GAP88272.1 - 8.3e-15 54.9 0.0 1.6e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 GAP88273.1 - 3.7e-21 75.5 0.0 3.6e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88273.1 - 2.8e-10 40.2 0.0 7e-10 38.9 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88273.1 - 2.9e-05 24.1 0.0 4.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP88273.1 - 0.0085 15.6 0.0 0.019 14.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 GAP88273.1 - 0.08 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Prp19 PF08606.11 GAP88273.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Prp19/Pso4-like Pkinase PF00069.25 GAP88274.1 - 2.4e-17 63.2 0.0 1e-16 61.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP88274.1 - 3.2e-09 36.5 0.0 2.9e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 GAP88274.1 - 6.2e-06 26.0 0.9 0.00025 20.8 0.1 2.5 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Aminotran_4 PF01063.19 GAP88275.1 - 1.8e-35 122.8 0.0 2.3e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV ESSS PF10183.9 GAP88276.1 - 9e-19 67.6 0.0 1.1e-18 67.4 0.0 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ATP-synt_E PF05680.12 GAP88276.1 - 0.0041 17.4 0.0 0.0076 16.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase E chain PIP49_C PF12260.8 GAP88276.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Seipin PF06775.14 GAP88278.1 - 1.6e-53 181.8 5.0 2e-53 181.5 5.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) ABC2_membrane_2 PF12679.7 GAP88278.1 - 0.11 11.8 4.0 0.039 13.2 1.2 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein FCH PF00611.23 GAP88279.1 - 8.6e-15 54.8 0.0 2.8e-14 53.2 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 GAP88279.1 - 4.1e-12 45.5 0.0 7.8e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 GAP88279.1 - 2.4e-10 40.0 0.0 1.3e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 GAP88279.1 - 3.1e-10 39.8 0.0 7.3e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Tup_N PF08581.10 GAP88279.1 - 0.065 13.5 0.1 0.21 11.9 0.1 1.9 1 0 0 1 1 1 0 Tup N-terminal Rapsyn_N PF10579.9 GAP88279.1 - 0.16 12.1 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Polyketide_cyc2 PF10604.9 GAP88280.1 - 8.7e-07 29.3 0.3 1.1e-06 29.0 0.3 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport GH131_N PF18271.1 GAP88281.1 - 4.6e-66 223.1 1.6 6.1e-66 222.7 1.6 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 GAP88281.1 - 3.9e-12 45.9 8.1 3.9e-12 45.9 8.1 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Polysacc_lyase PF14099.6 GAP88281.1 - 0.018 14.9 3.0 0.032 14.1 3.0 1.5 1 0 0 1 1 1 0 Polysaccharide lyase Sporozoite_P67 PF05642.11 GAP88281.1 - 2.8 5.9 8.1 3.4 5.6 8.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF346 PF03984.13 GAP88282.1 - 1.2e-09 37.7 27.9 0.0046 16.7 1.2 6.2 6 0 0 6 6 6 5 Repeat of unknown function (DUF346) Arginosuc_synth PF00764.19 GAP88285.1 - 1.2e-140 469.3 0.0 1.4e-140 469.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 GAP88285.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 GAP88285.1 - 0.0091 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 GAP88285.1 - 0.085 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase p450 PF00067.22 GAP88286.1 - 9.6e-52 176.3 0.0 1.3e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 GAP88287.1 - 8.7e-30 104.0 0.1 1.3e-29 103.4 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M24 PF00557.24 GAP88288.1 - 5.7e-22 78.4 0.0 7e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3958 PF13125.6 GAP88288.1 - 0.016 15.4 1.4 0.027 14.7 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) YnfE PF17452.2 GAP88288.1 - 0.1 12.9 0.3 0.23 11.8 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized YnfE-like adh_short PF00106.25 GAP88289.1 - 3.9e-25 88.5 0.2 6.2e-25 87.8 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88289.1 - 5e-19 68.8 0.6 5.9e-19 68.5 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88289.1 - 5.1e-05 23.3 0.2 7.8e-05 22.7 0.2 1.4 1 1 0 1 1 1 1 KR domain Glyco_hydro_3_C PF01915.22 GAP88290.1 - 1.2e-44 152.7 0.0 2.2e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAP88290.1 - 3.5e-42 144.9 0.0 5.1e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAP88290.1 - 9.4e-24 83.3 0.0 1.8e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CN_hydrolase PF00795.22 GAP88292.1 - 6.1e-30 104.4 0.0 7.7e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase adh_short PF00106.25 GAP88295.1 - 9.8e-23 80.6 0.1 1.1e-16 60.9 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88295.1 - 5.8e-17 62.0 0.1 2.8e-09 36.9 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88295.1 - 4.3e-05 23.5 0.2 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 KR domain p450 PF00067.22 GAP88296.1 - 3.5e-78 263.4 0.0 4.7e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_2 PF04909.14 GAP88297.1 - 7.6e-42 144.1 0.0 8.9e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase ketoacyl-synt PF00109.26 GAP88298.1 - 9.2e-87 290.8 0.1 6.1e-86 288.1 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAP88298.1 - 5.8e-68 229.7 0.0 9.1e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 GAP88298.1 - 1.4e-62 210.8 0.0 5.4e-62 208.9 0.0 2.1 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 GAP88298.1 - 2.5e-37 127.5 3.0 4.8e-37 126.6 1.6 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 GAP88298.1 - 1.8e-10 40.6 0.0 7.1e-10 38.6 0.0 1.9 1 1 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 GAP88298.1 - 4.2e-10 39.8 0.0 9.8e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAP88298.1 - 6.9e-10 39.4 0.0 1.6e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAP88298.1 - 3.8e-07 29.8 0.0 2.4e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 GAP88298.1 - 0.00023 20.6 0.2 0.00091 18.7 0.1 2.0 3 0 0 3 3 3 1 Thiolase, N-terminal domain VHS PF00790.19 GAP88300.1 - 8.9e-24 83.9 0.0 1.8e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 GAP88300.1 - 3.3e-07 30.5 0.5 7.8e-07 29.3 0.5 1.6 1 0 0 1 1 1 1 GAT domain zf_CCCH_4 PF18345.1 GAP88301.1 - 0.0059 16.6 5.0 0.24 11.5 0.5 2.8 2 0 0 2 2 2 2 Zinc finger domain ComGF PF15980.5 GAP88301.1 - 0.029 14.7 0.1 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 Putative Competence protein ComGF V-SNARE PF05008.15 GAP88301.1 - 0.058 13.8 7.9 0.16 12.4 7.9 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Exonuc_VII_L PF02601.15 GAP88301.1 - 0.12 11.9 1.1 0.15 11.6 0.2 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit zf-P11 PF03854.14 GAP88301.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.4 2 0 0 2 2 2 0 P-11 zinc finger PKcGMP_CC PF16808.5 GAP88301.1 - 0.23 11.4 2.2 0.63 9.9 2.2 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ion_trans_2 PF07885.16 GAP88302.1 - 2.5e-29 101.0 21.4 1.5e-15 56.9 1.7 3.3 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 GAP88302.1 - 2.8e-06 26.8 4.9 0.0012 18.2 0.0 2.8 2 1 1 3 3 3 2 Ion transport protein Abhydrolase_3 PF07859.13 GAP88303.1 - 0.00079 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2079 PF09852.9 GAP88303.1 - 0.048 12.5 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Abhydrolase_2 PF02230.16 GAP88303.1 - 0.16 11.8 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ribosomal_S24e PF01282.19 GAP88304.1 - 7.1e-30 102.8 0.4 1.8e-29 101.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S24e His_Phos_1 PF00300.22 GAP88305.1 - 1.4e-16 60.8 0.1 2e-15 57.0 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) PTPA PF03095.15 GAP88307.1 - 1.2e-121 405.8 0.0 1.4e-121 405.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein GAS PF13851.6 GAP88309.1 - 0.00014 21.2 15.6 0.00014 21.2 15.6 8.1 1 1 4 7 7 7 4 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 GAP88309.1 - 0.064 13.4 0.2 0.064 13.4 0.2 9.9 2 2 9 12 12 12 0 Fibrinogen alpha/beta chain family PKcGMP_CC PF16808.5 GAP88309.1 - 0.24 11.3 0.1 0.24 11.3 0.1 7.8 10 1 1 11 11 11 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAD_binding_4 PF01565.23 GAP88310.1 - 1.2e-06 28.4 0.3 2.2e-06 27.5 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP88310.1 - 0.021 14.9 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like p450 PF00067.22 GAP88311.1 - 2.5e-55 188.1 0.0 3e-54 184.5 0.0 2.4 1 1 0 1 1 1 1 Cytochrome P450 DUF3439 PF11921.8 GAP88311.1 - 0.82 9.7 4.7 1.5 8.8 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) JmjC PF02373.22 GAP88312.1 - 2e-17 63.6 0.0 3.3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase PS_Dcarbxylase PF02666.15 GAP88313.1 - 4.1e-51 173.4 0.0 5.8e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Abhydrolase_6 PF12697.7 GAP88315.1 - 0.0045 17.6 0.7 0.0055 17.3 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2786 PF10979.8 GAP88315.1 - 0.53 10.3 3.7 0.26 11.2 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) Granulin PF00396.18 GAP88316.1 - 0.096 13.0 21.5 0.16 12.4 6.6 2.7 1 1 1 2 2 2 0 Granulin Zds_C PF08632.10 GAP88317.1 - 1.1e-29 101.9 1.5 2.2e-29 101.0 1.5 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2433 PF10360.9 GAP88318.1 - 2.6e-48 163.2 0.0 4.6e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 GAP88318.1 - 0.001 19.6 0.0 0.002 18.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAP88318.1 - 0.0017 18.6 0.0 0.0056 16.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SOG2 PF10428.9 GAP88318.1 - 0.57 9.3 4.5 0.82 8.8 4.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ubie_methyltran PF01209.18 GAP88319.1 - 2e-49 168.0 0.0 2.2e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 GAP88319.1 - 1.5e-10 41.6 0.0 2.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP88319.1 - 1.6e-09 38.3 0.0 3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP88319.1 - 1.2e-07 32.4 0.0 1.8e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP88319.1 - 2.2e-05 24.3 0.0 2.8e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP88319.1 - 0.0026 17.6 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain E1_dh PF00676.20 GAP88320.1 - 5.4e-88 294.8 0.0 6.5e-88 294.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 GAP88320.1 - 0.0066 16.3 0.2 0.029 14.1 0.0 2.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HECT PF00632.25 GAP88321.1 - 1.1e-77 261.6 0.0 2.7e-77 260.3 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) CLASP_N PF12348.8 GAP88321.1 - 0.0013 18.3 1.6 0.042 13.4 0.0 2.9 3 0 0 3 3 3 1 CLASP N terminal Arm PF00514.23 GAP88321.1 - 0.0045 17.0 3.4 3.4 7.8 0.0 5.1 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GAP88321.1 - 0.014 15.6 0.9 2 8.9 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat TFIIA PF03153.13 GAP88321.1 - 1.7 8.6 59.9 0.015 15.3 27.3 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 GAP88321.1 - 3.5 7.6 29.4 2.1 8.4 6.9 3.8 3 0 0 3 3 3 0 RXT2-like, N-terminal Complex1_30kDa PF00329.19 GAP88323.1 - 8.1e-45 152.4 0.0 1.1e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.6 GAP88324.1 - 1.2e-19 69.8 11.2 2.3e-19 68.9 11.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 GAP88324.1 - 3.1e-09 36.5 0.0 7.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 GAP88324.1 - 3.2e-07 30.1 6.4 5.9e-07 29.2 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 GAP88324.1 - 2e-05 24.1 5.4 2e-05 24.1 5.4 3.2 3 1 0 3 3 2 1 Rtf2 RING-finger zf-RING_2 PF13639.6 GAP88324.1 - 0.00013 22.2 9.9 0.00031 21.0 9.9 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAP88324.1 - 0.0067 16.3 9.8 0.27 11.1 10.2 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Nup35_RRM_2 PF14605.6 GAP88324.1 - 0.019 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.11 GAP88324.1 - 0.021 14.8 4.4 0.038 13.9 4.4 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) SET_assoc PF11767.8 GAP88324.1 - 0.027 14.1 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-RING_5 PF14634.6 GAP88324.1 - 0.032 14.2 9.6 0.06 13.3 9.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FYVE PF01363.21 GAP88324.1 - 0.057 13.6 4.2 0.14 12.3 4.2 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-UDP PF14569.6 GAP88324.1 - 0.89 9.7 4.1 1.9 8.7 4.1 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 GAP88324.1 - 1.1 9.2 9.6 2.2 8.2 9.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP88324.1 - 1.8 8.7 7.3 2.4 8.3 5.8 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAP88324.1 - 2.7 7.9 9.6 5.6 6.9 9.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PAS_9 PF13426.7 GAP88325.1 - 1.4e-12 47.8 0.0 1.7e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 GAP88325.1 - 0.0044 17.3 0.0 0.06 13.7 0.0 2.1 1 1 0 1 1 1 1 PAS fold PAS PF00989.25 GAP88325.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.7 1 1 0 1 1 1 0 PAS fold PAS_8 PF13188.7 GAP88325.1 - 0.038 14.0 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.10 GAP88325.1 - 0.21 11.9 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 PAS fold Glyco_hydro_7 PF00840.20 GAP88326.1 - 1.7e-175 584.0 22.3 1.9e-175 583.8 22.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Trypan_PARP PF05887.11 GAP88327.1 - 0.0011 18.9 5.7 0.0019 18.2 5.7 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) KCH PF16944.5 GAP88329.1 - 1.7e-94 316.3 8.1 2.1e-94 316.0 8.1 1.1 1 0 0 1 1 1 1 Fungal potassium channel Putative_PNPOx PF01243.20 GAP88331.1 - 1e-07 32.0 0.0 3.8e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Serglycin PF04360.12 GAP88331.1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Serglycin Patched PF02460.18 GAP88332.1 - 2e-77 261.1 6.9 1.2e-50 172.5 0.0 2.1 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 GAP88332.1 - 3.6e-77 259.2 7.9 5.4e-77 258.7 7.9 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 GAP88332.1 - 2.7e-52 176.7 5.1 2.7e-52 176.7 5.1 2.9 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 GAP88332.1 - 9.6e-06 24.7 7.1 9.6e-06 24.7 7.1 2.8 2 1 0 2 2 2 1 MMPL family Folate_rec PF03024.14 GAP88332.1 - 1.4e-05 25.0 0.9 3.3e-05 23.8 0.9 1.6 1 0 0 1 1 1 1 Folate receptor family CTP_transf_like PF01467.26 GAP88333.1 - 2.1e-26 92.9 0.0 2.7e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like CUE PF02845.16 GAP88335.1 - 0.0051 16.5 0.7 0.25 11.1 0.3 2.6 2 0 0 2 2 2 2 CUE domain Lactamase_B_2 PF12706.7 GAP88336.1 - 1.8e-31 109.2 0.2 5.7e-30 104.3 0.2 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 GAP88336.1 - 2.8e-09 37.1 0.0 9.1e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAP88336.1 - 0.036 14.1 4.7 0.25 11.3 4.6 2.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Gryzun PF07919.12 GAP88337.1 - 1.2e-203 678.2 0.0 1.5e-203 677.9 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 GAP88337.1 - 2.3e-87 292.9 2.7 2.4e-81 273.2 2.9 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 GAP88337.1 - 0.0024 17.8 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF1622 PF07784.11 GAP88337.1 - 0.0025 17.7 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1622) RXT2_N PF08595.11 GAP88338.1 - 8.1e-46 155.9 0.1 8.1e-46 155.9 0.1 2.5 3 0 0 3 3 3 1 RXT2-like, N-terminal Glucodextran_B PF09136.10 GAP88338.1 - 0.11 12.9 0.6 0.18 12.2 0.6 1.3 1 0 0 1 1 1 0 Glucodextranase, domain B PEMT PF04191.13 GAP88339.1 - 7.7e-33 113.1 3.9 2e-32 111.8 2.7 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase Nramp PF01566.18 GAP88340.1 - 1.7e-89 300.3 15.8 1.7e-89 300.3 15.8 1.8 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein MAP17 PF15807.5 GAP88340.1 - 1.4 9.2 4.6 0.97 9.7 2.3 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FGGY_C PF02782.16 GAP88341.1 - 6.3e-73 244.7 0.3 1.3e-72 243.7 0.3 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 GAP88341.1 - 1.9e-61 207.7 0.0 2.6e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain NAD_binding_4 PF07993.12 GAP88342.1 - 3.2e-31 108.4 0.0 4.9e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAP88342.1 - 1.2e-23 83.4 0.0 1.8e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAP88342.1 - 6e-10 39.3 0.1 1.3e-09 38.3 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 GAP88342.1 - 1.9e-08 34.1 0.0 3.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 GAP88342.1 - 0.017 15.1 0.3 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 KR domain TRI12 PF06609.13 GAP88343.1 - 2.7e-10 39.3 2.2 2.7e-10 39.3 2.2 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 GAP88343.1 - 6.5e-08 31.9 38.8 2.3e-07 30.1 10.1 3.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3611 PF12263.8 GAP88343.1 - 8.1 6.3 12.6 2.7 7.8 0.9 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3611) Cation_efflux PF01545.21 GAP88344.1 - 1.2e-24 87.1 12.5 1.5e-24 86.9 12.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAP88344.1 - 6.5e-08 32.6 0.1 1.2e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Zip PF02535.22 GAP88345.1 - 3.2e-52 177.8 4.1 3.7e-52 177.6 4.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Dioxygenase_C PF00775.21 GAP88346.1 - 4.4e-43 146.8 0.0 5.9e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 GAP88346.1 - 2.1e-21 75.5 0.1 3.2e-21 75.0 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus SpaA PF17802.1 GAP88346.1 - 0.039 14.3 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 Prealbumin-like fold domain Lactonase PF10282.9 GAP88347.1 - 4.6e-17 62.3 0.0 5.8e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF21 PF01595.20 GAP88348.1 - 9.9e-34 116.6 0.0 1.7e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 GAP88348.1 - 6.6e-05 23.3 0.3 0.024 15.1 0.0 3.0 2 0 0 2 2 2 2 CBS domain DED PF01335.21 GAP88348.1 - 0.18 12.2 0.2 0.85 10.0 0.2 2.1 2 0 0 2 2 2 0 Death effector domain Zn_clus PF00172.18 GAP88351.1 - 1.5e-09 37.8 11.7 2.5e-09 37.1 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP88351.1 - 4.8e-05 22.5 0.0 0.00022 20.4 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Copper-fist PF00649.18 GAP88353.1 - 1.5e-22 78.8 2.3 1.5e-22 78.8 2.3 3.4 1 1 3 4 4 4 1 Copper fist DNA binding domain ApbA PF02558.16 GAP88355.1 - 5.7e-29 100.7 0.0 1e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 GAP88355.1 - 3.7e-25 88.6 0.0 6.7e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal PHY PF00360.20 GAP88356.1 - 4.1e-31 107.7 0.0 9.7e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 GAP88356.1 - 1.2e-18 67.7 1.2 2e-18 66.9 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAP88356.1 - 2e-16 60.2 0.1 8.2e-16 58.2 0.0 2.2 2 1 0 2 2 2 1 Response regulator receiver domain GAF PF01590.26 GAP88356.1 - 4.1e-12 46.9 0.0 1.2e-11 45.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 GAP88356.1 - 1.6e-11 44.0 1.8 4.9e-11 42.5 0.5 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 GAP88356.1 - 2.7e-08 34.5 0.0 7.2e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 GAP88356.1 - 0.0016 18.3 0.0 0.0042 16.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Spt20 PF12090.8 GAP88356.1 - 4.2 6.9 18.0 9.6 5.7 18.0 1.5 1 0 0 1 1 1 0 Spt20 family MFS_1 PF07690.16 GAP88357.1 - 3.2e-34 118.4 25.8 3.3e-34 118.4 24.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Chromo_shadow PF01393.19 GAP88358.1 - 6.1e-20 71.1 2.7 2.1e-17 63.0 0.2 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 GAP88358.1 - 5.8e-13 48.5 1.0 5.8e-13 48.5 1.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DNA_pol_phi PF04931.13 GAP88358.1 - 5.8 4.9 12.8 7.5 4.5 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-Di19 PF05605.12 GAP88359.1 - 0.018 15.4 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 GAP88359.1 - 0.044 14.6 0.1 0.11 13.4 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 GAP88359.1 - 0.054 13.4 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Atg14 PF10186.9 GAP88359.1 - 0.096 11.8 0.6 0.2 10.7 0.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2H2 PF00096.26 GAP88359.1 - 0.1 13.1 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 GAP88359.1 - 0.18 11.2 0.2 0.33 10.4 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Glyco_hydro_16 PF00722.21 GAP88360.1 - 7.3e-42 142.8 2.3 7.3e-42 142.8 2.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 SAPS PF04499.15 GAP88360.1 - 0.73 8.5 2.2 0.98 8.1 2.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PP_M1 PF03012.14 GAP88360.1 - 2 7.9 6.9 2.8 7.4 6.9 1.2 1 0 0 1 1 1 0 Phosphoprotein zf-RING_7 PF02591.15 GAP88361.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 0 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 GAP88361.1 - 0.055 12.9 1.4 0.29 10.6 0.1 2.4 2 1 0 2 2 2 0 zinc-ribbon domain Ogr_Delta PF04606.12 GAP88361.1 - 0.18 11.8 0.6 6.8 6.8 0.3 2.3 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.10 GAP88361.1 - 0.52 10.5 0.1 0.52 10.5 0.1 2.2 2 1 0 2 2 2 0 Zinc ribbon domain TCO89 PF10452.9 GAP88362.1 - 2.6e-09 36.6 0.2 2.6e-09 36.6 0.2 2.9 2 2 0 2 2 2 1 TORC1 subunit TCO89 Glyco_hydro_16 PF00722.21 GAP88363.1 - 8.4e-14 51.4 1.3 1.2e-13 51.0 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.18 GAP88364.1 - 2.2e-19 69.5 0.0 5.5e-19 68.2 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 GAP88365.1 - 3.1e-33 115.3 0.0 4.1e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP88365.1 - 3.7e-11 43.4 0.2 2.6e-08 34.3 0.3 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP88365.1 - 0.0004 19.7 0.0 0.002 17.5 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP88365.1 - 0.0013 17.9 0.0 0.0047 16.1 0.0 1.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 GAP88365.1 - 0.034 14.1 0.1 7.7 6.5 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 GAP88365.1 - 0.35 10.4 8.4 8.5 5.8 0.0 3.8 2 1 0 4 4 4 0 FAD dependent oxidoreductase Dna2 PF08696.11 GAP88367.1 - 2e-68 230.2 0.0 4.2e-68 229.2 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 GAP88367.1 - 3.7e-52 176.8 0.0 8e-52 175.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAP88367.1 - 4.5e-33 115.2 0.5 9.9e-17 61.6 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 GAP88367.1 - 4.4e-14 52.7 0.0 9.3e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAP88367.1 - 4.3e-12 46.6 0.0 1.2e-11 45.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 GAP88367.1 - 2.9e-08 34.0 0.1 1.3e-07 31.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 GAP88367.1 - 1.6e-05 24.8 0.1 1.2 8.9 0.1 3.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 GAP88367.1 - 0.00016 21.6 0.0 0.00041 20.2 0.0 1.7 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 GAP88367.1 - 0.00029 20.5 0.0 0.00063 19.4 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 GAP88367.1 - 0.0035 17.8 0.0 0.015 15.7 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 GAP88367.1 - 0.0037 16.9 0.1 0.0074 15.9 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.14 GAP88367.1 - 0.0055 15.9 0.1 0.11 11.6 0.2 2.3 2 0 0 2 2 2 1 PIF1-like helicase CbiA PF01656.23 GAP88367.1 - 0.022 14.8 0.2 0.048 13.7 0.2 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RuvB_N PF05496.12 GAP88367.1 - 0.045 13.5 0.1 0.096 12.4 0.1 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 GAP88367.1 - 0.051 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 GAP88367.1 - 0.056 13.0 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MobB PF03205.14 GAP88367.1 - 0.096 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 GAP88367.1 - 0.11 12.6 0.2 0.29 11.2 0.2 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 GAP88367.1 - 0.13 12.7 0.1 0.36 11.3 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 GAP88367.1 - 0.14 11.1 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 GAP88367.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 GAP88367.1 - 0.21 11.5 0.8 0.53 10.2 0.3 1.8 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 GAP88367.1 - 0.24 11.7 0.5 3.4 7.9 0.3 3.1 2 1 0 2 2 2 0 AAA domain FtsJ PF01728.19 GAP88368.1 - 2.9e-64 216.4 0.0 4.1e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.29 GAP88369.1 - 9.2e-44 149.3 0.0 2.8e-43 147.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP88369.1 - 6.4e-28 97.3 0.0 2.9e-27 95.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP88369.1 - 1.2e-05 25.4 0.4 5.6e-05 23.2 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PAP_RNA-bind PF04926.15 GAP88369.1 - 0.038 13.6 0.6 0.37 10.4 0.3 2.4 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain Methyltransf_25 PF13649.6 GAP88370.1 - 2.2e-10 41.1 0.0 9.8e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP88370.1 - 3.1e-10 40.6 0.0 7.5e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP88370.1 - 9.2e-06 26.3 0.0 1.5e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP88370.1 - 3.9e-05 23.1 0.0 6.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAP88370.1 - 0.00038 20.3 0.0 0.00056 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_C37 PF05416.12 GAP88370.1 - 0.044 12.3 0.3 0.09 11.3 0.0 1.5 2 0 0 2 2 2 0 Southampton virus-type processing peptidase NNMT_PNMT_TEMT PF01234.17 GAP88370.1 - 0.057 12.6 0.0 8 5.6 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family SUR7 PF06687.12 GAP88372.1 - 2.4e-05 24.1 0.0 5.6e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 SUR7/PalI family A_deaminase PF00962.22 GAP88374.1 - 1.7e-28 99.9 0.0 2.7e-27 96.0 0.0 2.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase Tyosinase_C PF18132.1 GAP88374.1 - 0.044 14.4 0.0 0.082 13.6 0.0 1.4 1 0 0 1 1 1 0 Tyosinase C-terminal domain SRP40_C PF05022.12 GAP88375.1 - 1.8e-23 83.1 0.6 6.6e-23 81.4 0.6 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain ArsB PF02040.15 GAP88377.1 - 1.2e-10 41.3 20.5 1e-05 25.1 8.2 2.4 2 0 0 2 2 2 2 Arsenical pump membrane protein DUF4293 PF14126.6 GAP88377.1 - 0.72 10.1 6.4 0.13 12.5 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) DUF3099 PF11298.8 GAP88378.1 - 0.28 11.3 3.9 0.93 9.7 3.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) Complex1_51K PF01512.17 GAP88379.1 - 1.2e-46 158.3 0.0 2e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 GAP88379.1 - 2e-28 98.3 1.3 3e-28 97.7 0.1 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 GAP88379.1 - 4.2e-09 36.1 0.0 1e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Hexapep PF00132.24 GAP88380.1 - 7.6e-08 31.8 12.0 3.7e-06 26.4 1.9 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAP88380.1 - 0.029 14.1 7.8 3.8 7.4 0.1 3.4 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase p450 PF00067.22 GAP88381.1 - 9.8e-57 192.7 0.0 1.4e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Band_7 PF01145.25 GAP88382.1 - 2.8e-31 108.9 0.7 4.5e-31 108.2 0.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 GAP88382.1 - 4.9e-23 80.9 0.1 1.3e-22 79.6 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 GAP88382.1 - 0.023 14.0 0.2 0.033 13.5 0.2 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein GSH-S_N PF02951.14 GAP88382.1 - 0.069 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Band_7_1 PF13421.6 GAP88382.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family DCB PF16213.5 GAP88383.1 - 2.2e-48 164.3 3.7 6.3e-46 156.3 1.7 3.2 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 GAP88383.1 - 4.3e-39 134.0 0.2 2.9e-36 124.8 0.0 3.5 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 GAP88383.1 - 1.3e-24 86.4 5.5 1.3e-19 69.9 3.1 3.3 3 0 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 GAP88383.1 - 1.9e-06 27.6 0.0 0.0016 18.2 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Neuromodulin PF06614.11 GAP88383.1 - 0.0047 17.1 0.4 0.011 15.9 0.4 1.6 1 0 0 1 1 1 1 Neuromodulin 3HBOH PF10605.9 GAP88383.1 - 0.011 14.1 0.2 0.016 13.4 0.2 1.2 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Ceramidase_alk PF04734.13 GAP88384.1 - 3.2e-217 722.1 0.0 3.8e-217 721.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 GAP88384.1 - 6.2e-61 205.1 0.0 1.1e-60 204.3 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal DUF4192 PF13830.6 GAP88385.1 - 0.0083 16.2 0.3 0.0095 16.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4192) LPD5 PF18799.1 GAP88385.1 - 0.067 13.6 0.0 0.077 13.4 0.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 Glucosamine_iso PF01182.20 GAP88386.1 - 3.1e-21 76.3 0.0 5.1e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_1 PF00349.21 GAP88387.1 - 5.8e-45 153.6 0.0 1.5e-44 152.3 0.0 1.6 1 1 1 2 2 2 1 Hexokinase Hexokinase_2 PF03727.16 GAP88387.1 - 7.3e-31 107.4 0.0 1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase RGS PF00615.19 GAP88387.1 - 0.2 11.9 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain NDT80_PhoG PF05224.12 GAP88388.1 - 1.1e-33 117.0 0.0 2.4e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.21 GAP88389.1 - 1.4e-59 202.1 0.0 1.9e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 GAP88389.1 - 3.8e-05 23.9 0.0 9.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Aldedh PF00171.22 GAP88389.1 - 0.071 11.6 0.1 0.13 10.8 0.1 1.3 1 0 0 1 1 1 0 Aldehyde dehydrogenase family DUF3972 PF13118.6 GAP88389.1 - 0.12 12.9 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Glyco_hydro_3_C PF01915.22 GAP88389.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Amidohydro_1 PF01979.20 GAP88390.1 - 2.2e-12 47.0 0.0 3.8e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAP88390.1 - 2.9e-10 40.2 0.0 1.9e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family UvrD-helicase PF00580.21 GAP88391.1 - 2.7e-64 217.7 0.1 5.5e-62 210.1 0.1 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 GAP88391.1 - 1.2e-60 205.8 0.0 2.1e-60 204.9 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 GAP88391.1 - 4.9e-30 104.8 0.0 4.9e-30 104.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 GAP88391.1 - 2.5e-14 52.8 0.0 7.1e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 GAP88391.1 - 3.4e-06 27.0 0.0 0.28 10.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 GAP88391.1 - 0.00094 19.0 10.2 0.0011 18.8 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_12 PF13087.6 GAP88391.1 - 0.00099 18.8 0.0 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAP88391.1 - 0.0046 16.8 0.4 0.026 14.3 0.4 2.2 1 1 0 1 1 1 1 AAA domain DUF2014 PF09427.10 GAP88393.1 - 3.2e-106 354.5 7.8 4.7e-106 354.0 7.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 GAP88393.1 - 8.3e-17 60.9 0.9 1.9e-16 59.7 0.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NepR PF18557.1 GAP88393.1 - 0.045 13.4 1.0 0.12 12.1 1.0 1.7 1 0 0 1 1 1 0 Anti-sigma factor NepR CIA30 PF08547.12 GAP88394.1 - 1.1e-36 126.2 0.0 1.3e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.21 GAP88395.1 - 0.0012 18.9 7.7 0.0023 18.0 7.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAP88395.1 - 0.0056 16.7 7.0 0.01 15.9 7.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAP88395.1 - 8.2 7.0 11.8 3.6 8.2 7.0 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor Na_H_Exchanger PF00999.21 GAP88396.1 - 3.5e-62 210.4 44.1 4.9e-62 209.9 44.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Methyltransf_23 PF13489.6 GAP88397.1 - 4e-19 69.1 0.0 5.1e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP88397.1 - 1.3e-09 38.6 0.0 3.1e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP88397.1 - 3.1e-08 33.6 0.0 4.4e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP88397.1 - 3.6e-07 30.7 0.0 7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP88397.1 - 1.6e-05 25.5 0.0 6.1e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 GAP88397.1 - 0.025 14.3 0.0 0.028 14.2 0.0 1.4 1 1 0 1 1 1 0 Met-10+ like-protein MTS PF05175.14 GAP88397.1 - 0.047 13.3 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 GAP88397.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase zf-CCCH PF00642.24 GAP88398.1 - 0.027 14.4 2.5 0.63 10.0 0.1 2.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Lustrin_cystein PF14625.6 GAP88398.1 - 9.7 6.7 9.2 3 8.3 3.1 2.8 2 1 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Rcd1 PF04078.13 GAP88399.1 - 5.3e-125 415.9 4.1 6.1e-125 415.7 4.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pkinase PF00069.25 GAP88400.1 - 1.9e-68 230.7 0.0 4e-68 229.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP88400.1 - 5.9e-38 130.6 0.0 1.6e-37 129.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 GAP88400.1 - 1.2e-19 69.8 0.2 2.4e-19 68.9 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 GAP88400.1 - 1.4e-06 27.5 0.0 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAP88400.1 - 2.6e-05 23.7 0.1 4.8e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAP88400.1 - 8.2e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAP88400.1 - 0.003 17.5 0.0 0.018 14.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAP88400.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 GAP88400.1 - 0.37 10.3 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Med13_C PF06333.12 GAP88401.1 - 9.5e-92 307.8 0.7 9.5e-92 307.8 0.7 2.5 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 GAP88401.1 - 1.6e-24 86.9 1.3 7.2e-24 84.7 1.3 2.1 1 1 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 GAP88401.1 - 1.5e-11 44.6 1.6 0.0002 21.3 0.0 3.3 3 0 0 3 3 3 2 MID domain of medPIWI NUC153 PF08159.12 GAP88402.1 - 2.4e-13 49.6 2.2 4.8e-13 48.7 2.2 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 GAP88402.1 - 0.00065 20.5 0.0 0.52 11.3 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP88402.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Indigoidine_A PF04227.12 GAP88403.1 - 0.099 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Indigoidine synthase A like protein LapA_dom PF06305.11 GAP88403.1 - 0.18 11.6 0.8 0.28 11.0 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pyridox_ox_2 PF12900.7 GAP88405.1 - 1.2e-32 112.9 0.0 2.3e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Glyco_hydro_47 PF01532.20 GAP88406.1 - 2.1e-136 455.5 0.0 2.4e-136 455.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rad10 PF03834.14 GAP88407.1 - 1.2e-46 157.4 0.0 1.8e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 GAP88407.1 - 0.00015 22.3 0.0 0.0003 21.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain SPX PF03105.19 GAP88407.1 - 0.044 13.7 5.7 0.074 13.0 5.7 1.4 1 1 0 1 1 1 0 SPX domain Spermine_synth PF01564.17 GAP88408.1 - 4.9e-05 22.8 0.0 0.00012 21.6 0.0 1.6 1 1 0 1 1 1 1 Spermine/spermidine synthase domain PIN7 PF18475.1 GAP88409.1 - 0.21 12.3 0.4 0.39 11.4 0.4 1.4 1 0 0 1 1 1 0 PIN domain DUF5305 PF17231.2 GAP88409.1 - 0.23 10.9 10.1 0.21 11.0 7.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF5401 PF17380.2 GAP88409.1 - 0.28 9.2 6.0 0.35 8.9 6.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) MASE1 PF05231.14 GAP88409.1 - 2.7 7.1 22.1 2.8 7.0 13.3 3.4 2 1 0 2 2 2 0 MASE1 DUF4064 PF13273.6 GAP88409.1 - 4.4 7.6 7.9 1.3 9.3 3.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Peptidase_M35 PF02102.15 GAP88410.1 - 1.2e-91 307.2 19.1 1.6e-91 306.9 19.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 GAP88410.1 - 1.8e-43 148.6 2.0 1.8e-43 148.6 2.0 1.9 1 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase adh_short PF00106.25 GAP88412.1 - 2.9e-15 56.3 0.3 3.4e-15 56.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88412.1 - 6.6e-09 35.7 0.1 9.2e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88412.1 - 0.00026 20.9 0.2 0.00034 20.6 0.2 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 GAP88412.1 - 0.047 13.0 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.15 GAP88412.1 - 0.048 13.8 0.1 0.2 11.8 0.1 1.8 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Alba PF01918.21 GAP88412.1 - 0.051 13.4 0.1 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 Alba ATP_bind_2 PF03668.15 GAP88412.1 - 0.075 12.3 0.1 0.097 12.0 0.1 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family Epimerase PF01370.21 GAP88412.1 - 0.097 12.1 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 GAP88413.1 - 5.9e-25 88.2 0.4 8.6e-25 87.7 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP88413.1 - 4.4e-18 65.4 0.0 5.8e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase FBPase PF00316.20 GAP88415.1 - 8.5e-71 237.3 0.1 1.1e-70 237.0 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Sec3_C PF09763.9 GAP88416.1 - 4.6e-237 788.9 2.5 5.8e-237 788.5 2.5 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 GAP88416.1 - 2.9e-29 101.0 0.0 6e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 GAP88416.1 - 8.2e-05 22.9 1.3 0.001 19.4 0.0 2.6 2 0 0 2 2 2 1 Sec3 exocyst complex subunit Vps52 PF04129.12 GAP88416.1 - 0.026 13.3 1.2 0.81 8.4 0.2 2.2 2 0 0 2 2 2 0 Vps52 / Sac2 family TBCC_N PF16752.5 GAP88416.1 - 0.069 13.6 5.4 9.7 6.7 0.7 4.8 3 1 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Peptidase_S58 PF03576.14 GAP88417.1 - 3.8e-118 394.4 0.2 4.3e-118 394.2 0.2 1.0 1 0 0 1 1 1 1 Peptidase family S58 Fe-ADH PF00465.19 GAP88418.1 - 3.9e-104 348.4 0.1 5.1e-104 348.0 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 GAP88418.1 - 1.8e-16 60.6 0.1 2.9e-13 50.1 0.1 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 GAP88418.1 - 0.0011 18.8 0.1 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Methyltransf_25 PF13649.6 GAP88419.1 - 3.5e-11 43.6 0.1 1.8e-10 41.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP88419.1 - 5e-10 39.9 0.1 1.3e-09 38.5 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP88419.1 - 3.1e-07 30.3 0.0 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP88419.1 - 9.5e-06 25.1 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAP88419.1 - 4.2e-05 23.4 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP88419.1 - 5.6e-05 23.8 0.0 0.00012 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Amidohydro_2 PF04909.14 GAP88419.1 - 4.8 6.9 7.8 7.3 6.3 7.8 1.3 1 1 0 1 1 1 0 Amidohydrolase Sugar_tr PF00083.24 GAP88421.1 - 7.9e-61 206.3 9.9 1.1e-60 205.9 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP88421.1 - 7.8e-34 117.1 16.3 1.1e-33 116.7 16.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAP88421.1 - 7.3e-05 22.2 4.1 7.3e-05 22.2 4.1 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 GAP88421.1 - 0.00022 19.9 5.3 0.00022 19.9 5.3 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.13 GAP88421.1 - 0.0014 17.1 7.4 0.0025 16.3 4.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 GAP88421.1 - 0.0015 17.5 0.6 0.48 9.2 4.0 2.7 1 1 1 2 2 2 1 MFS_1 like family Phage_holin_3_2 PF04550.12 GAP88421.1 - 0.035 14.6 0.3 0.11 13.0 0.3 1.8 1 0 0 1 1 1 0 Phage holin family 2 PUCC PF03209.15 GAP88421.1 - 0.086 11.8 6.4 0.029 13.4 1.9 2.0 1 1 1 2 2 2 0 PUCC protein Sugar_tr PF00083.24 GAP88422.1 - 4.6e-08 32.4 0.6 5.2e-08 32.2 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Terpene_synth_C PF03936.16 GAP88424.1 - 0.0031 16.9 0.0 0.008 15.5 0.0 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Caps_synth PF05704.12 GAP88425.1 - 1.3e-12 47.7 0.0 2.6e-12 46.7 0.0 1.4 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 GAP88425.1 - 0.00068 20.2 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif p450 PF00067.22 GAP88426.1 - 6.1e-39 134.0 0.0 8.4e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TraI_2 PF07514.11 GAP88426.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative helicase Asparaginase_2 PF01112.18 GAP88427.1 - 5.6e-55 186.5 5.2 1.1e-26 93.6 0.0 3.9 3 2 0 3 3 3 3 Asparaginase Peptidase_M20 PF01546.28 GAP88428.1 - 9.1e-24 84.3 0.0 1.7e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 GAP88428.1 - 5.2e-12 46.1 6.9 0.36 11.8 0.1 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.14 GAP88428.1 - 1.1e-07 31.7 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAP88428.1 - 0.00059 19.6 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Ge1_WD40 PF16529.5 GAP88428.1 - 0.027 13.4 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 GAP88428.1 - 0.033 14.5 0.1 5.5 7.4 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 GAP88431.1 - 0.058 12.8 8.6 0.081 12.3 8.6 1.3 1 0 0 1 1 1 0 SDA1 PI-PLC-X PF00388.19 GAP88433.1 - 1.7e-65 219.0 0.0 2.6e-65 218.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAP88433.1 - 2e-42 144.2 0.0 3.7e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 GAP88433.1 - 3.7e-06 27.2 0.0 1.5e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 C2 domain YL1 PF05764.13 GAP88433.1 - 0.01 16.0 1.3 0.021 15.0 1.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein FAM104 PF15434.6 GAP88433.1 - 0.12 13.0 1.2 0.34 11.5 1.2 1.8 1 0 0 1 1 1 0 Family 104 Lactamase_B_2 PF12706.7 GAP88434.1 - 4.9e-08 32.7 0.0 1.4e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.14 GAP88434.1 - 0.00057 20.0 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 GAP88434.1 - 0.00093 19.2 0.0 0.0019 18.2 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Pkinase PF00069.25 GAP88437.1 - 7.2e-12 45.2 0.1 3.1e-05 23.5 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 GAP88437.1 - 0.015 14.6 0.2 0.93 8.7 0.1 2.7 2 1 0 2 2 2 0 Protein tyrosine kinase MFS_1 PF07690.16 GAP88438.1 - 3.1e-12 46.1 34.1 4.4e-10 39.0 20.4 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 GAP88438.1 - 0.39 10.5 3.5 0.12 12.2 0.4 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) OATP PF03137.20 GAP88438.1 - 2.4 6.3 8.4 1.4 7.1 0.6 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2456 PF10445.9 GAP88439.1 - 2.1e-15 56.5 2.3 2.1e-15 56.5 2.3 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2456) Sigma_reg_N PF13800.6 GAP88439.1 - 0.23 11.8 1.1 3 8.2 0.1 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Vut_1 PF02592.15 GAP88439.1 - 0.24 11.7 5.8 0.2 12.0 0.6 2.2 2 0 0 2 2 2 0 Putative vitamin uptake transporter Aldedh PF00171.22 GAP88440.1 - 3.7e-137 457.6 0.0 4.3e-137 457.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAP88440.1 - 0.039 13.0 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) HET PF06985.11 GAP88441.1 - 5.8e-24 85.1 0.0 8.9e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 GAP88442.1 - 7.2e-49 166.8 0.0 9.7e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4153 PF13687.6 GAP88442.1 - 0.18 11.4 0.4 0.3 10.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4153) p450 PF00067.22 GAP88443.1 - 0.0051 15.6 0.0 0.0058 15.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flagellin_C PF00700.21 GAP88444.1 - 0.12 12.8 0.1 0.57 10.6 0.0 2.0 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region GBP_repeat PF02526.14 GAP88444.1 - 0.13 12.0 0.2 4 7.2 0.0 2.5 2 1 0 2 2 2 0 Glycophorin-binding protein DUF4880 PF16220.5 GAP88444.1 - 0.3 11.0 7.3 2.2 8.2 4.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4880) adh_short PF00106.25 GAP88445.1 - 4.5e-35 120.9 0.1 6.2e-35 120.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88445.1 - 7.3e-26 91.2 0.1 9.6e-26 90.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 GAP88445.1 - 0.00016 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 GAP88445.1 - 0.00032 20.7 0.0 0.00072 19.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 GAP88445.1 - 0.00073 19.1 0.0 0.018 14.5 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP88445.1 - 0.0011 18.9 0.0 0.0086 16.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding DUF1776 PF08643.10 GAP88445.1 - 0.0031 16.9 0.0 0.038 13.3 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 GAP88445.1 - 0.026 13.9 0.0 0.062 12.7 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAP88445.1 - 0.032 14.4 0.0 0.097 12.8 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 GAP88445.1 - 0.053 13.2 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 GAP88445.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 GAP88445.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 GAP88445.1 - 0.092 13.3 0.1 0.49 11.0 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 GAP88445.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.16 GAP88446.1 - 1e-36 126.6 46.4 1e-36 126.6 46.4 2.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP88446.1 - 2.4e-14 52.7 26.3 3.5e-14 52.1 26.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP88446.1 - 1.7e-06 27.2 12.1 1.7e-06 27.2 12.1 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter adh_short PF00106.25 GAP88447.1 - 2.6e-20 72.7 0.0 5e-16 58.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88447.1 - 7.9e-06 25.6 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88447.1 - 9.6e-05 22.4 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 GAP88448.1 - 3.3e-23 82.1 0.1 4.6e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88448.1 - 1.1e-15 57.9 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88448.1 - 1.5e-06 28.3 0.0 5.2e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAP88448.1 - 0.00014 21.4 0.8 0.0037 16.7 0.8 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP88448.1 - 0.066 12.6 0.8 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAP88448.1 - 0.076 12.9 0.2 0.19 11.6 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H-binding FAD_binding_4 PF01565.23 GAP88449.1 - 4.2e-20 71.9 3.9 6.9e-20 71.2 3.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP88449.1 - 7.4e-07 29.2 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cupin_2 PF07883.11 GAP88450.1 - 3.3e-06 26.7 0.1 5.5e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.25 GAP88451.1 - 6.7e-23 81.2 0.0 9.1e-20 70.9 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88451.1 - 2.9e-09 36.8 0.0 4.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88451.1 - 2.9e-08 33.8 0.1 4.8e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP88451.1 - 0.00047 19.7 0.0 0.00062 19.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 GAP88451.1 - 0.13 11.3 0.0 0.23 10.6 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_4 PF01565.23 GAP88452.1 - 2.9e-23 82.1 0.1 6.2e-23 81.1 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP88452.1 - 1.4e-09 37.9 0.5 3.5e-09 36.6 0.5 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 GAP88453.1 - 4.9e-36 124.0 0.3 6.1e-36 123.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88453.1 - 9.3e-26 90.8 0.0 1.3e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 GAP88453.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Cupin_2 PF07883.11 GAP88454.1 - 3.7e-07 29.8 0.5 3e-06 26.9 0.0 2.5 2 1 1 3 3 3 1 Cupin domain adh_short_C2 PF13561.6 GAP88455.1 - 1.1e-51 175.6 2.7 3.3e-51 174.1 2.7 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP88455.1 - 1.4e-36 125.8 0.5 2.6e-36 124.9 0.5 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP88455.1 - 2.6e-07 30.7 0.4 9.3e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_2 PF03446.15 GAP88455.1 - 0.011 15.9 0.0 0.049 13.8 0.0 2.0 1 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ketoacyl-synt PF00109.26 GAP88456.1 - 2.2e-68 230.6 0.0 4.8e-68 229.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP88456.1 - 9.4e-54 182.0 0.0 2.1e-53 180.9 0.0 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 GAP88456.1 - 1.1e-49 169.3 0.0 1.7e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP88456.1 - 2.5e-49 168.5 0.6 4.5e-49 167.7 0.6 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP88456.1 - 1.3e-36 125.2 0.2 9.1e-36 122.5 0.1 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 GAP88456.1 - 3.5e-16 60.5 0.0 4.2e-15 57.0 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAP88456.1 - 6.7e-13 48.8 2.8 1.8e-12 47.4 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 GAP88456.1 - 3.2e-12 46.9 0.1 8.7e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAP88456.1 - 2.4e-08 33.7 0.0 6.2e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 GAP88456.1 - 0.00019 21.3 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 GAP88456.1 - 0.00023 20.6 0.1 0.00049 19.6 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 GAP88456.1 - 0.012 15.5 0.1 0.038 13.8 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.25 GAP88456.1 - 0.019 15.3 0.0 0.054 13.8 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site Glyco_hydro_61 PF03443.14 GAP88457.1 - 9.3e-55 185.7 0.0 1.5e-54 185.0 0.0 1.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Lipase_GDSL_2 PF13472.6 GAP88458.1 - 1.2e-13 51.8 0.4 8.7e-13 49.0 0.2 2.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP88458.1 - 6.8e-12 45.8 0.1 1.3e-11 44.9 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 GAP88458.1 - 0.065 13.4 0.0 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family UPF0004 PF00919.20 GAP88459.1 - 0.031 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 FXa_inhibition PF14670.6 GAP88460.1 - 0.01 16.1 2.9 0.23 11.7 0.2 2.5 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site MRC1 PF09444.10 GAP88461.1 - 0.069 13.7 0.2 0.11 13.0 0.2 1.2 1 0 0 1 1 1 0 MRC1-like domain SR-25 PF10500.9 GAP88461.1 - 0.13 11.9 25.8 1.6 8.3 24.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HSD3 PF15244.6 GAP88461.1 - 0.75 9.2 11.3 1 8.8 11.3 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Macoilin PF09726.9 GAP88461.1 - 2.5 6.6 8.8 2.7 6.5 8.8 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 GAP88461.1 - 2.7 6.8 9.9 3.2 6.5 9.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SBDS_C PF09377.10 GAP88462.1 - 4.1e-46 155.8 0.1 6.4e-46 155.1 0.1 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 GAP88462.1 - 4.3e-33 113.2 0.0 7.5e-33 112.5 0.0 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Med3 PF11593.8 GAP88462.1 - 0.52 9.4 6.4 0.69 9.0 6.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_60s PF00428.19 GAP88462.1 - 0.98 10.0 14.1 1.4 9.5 6.5 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein K_channel_TID PF07941.11 GAP88462.1 - 6.6 7.3 8.9 19 5.8 0.1 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Peptidase_S10 PF00450.22 GAP88463.1 - 1e-129 433.7 4.1 1.2e-129 433.4 4.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 GAP88463.1 - 5.3e-15 56.1 0.0 1.3e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide SVS_QK PF10578.9 GAP88463.1 - 0.097 13.3 0.3 0.27 11.9 0.3 1.8 1 0 0 1 1 1 0 Seminal vesicle protein repeat Methyltransf_11 PF08241.12 GAP88464.1 - 5.1e-11 43.1 0.0 8.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP88464.1 - 6.8e-09 35.7 0.0 8.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP88464.1 - 3.3e-08 34.1 0.0 7.3e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP88464.1 - 0.00095 19.9 0.0 0.0016 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cas1_AcylT PF07779.12 GAP88465.1 - 2.4e-92 310.4 18.7 4.2e-92 309.5 18.7 1.3 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF2834 PF11196.8 GAP88466.1 - 0.0024 18.2 4.1 0.3 11.5 0.2 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF2834) Barttin PF15462.6 GAP88466.1 - 2.2 8.0 4.3 3.5 7.4 4.3 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Arf PF00025.21 GAP88467.1 - 1.4e-40 138.6 0.0 2e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GAP88467.1 - 1.6e-15 57.2 0.0 4.2e-10 39.3 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 GAP88467.1 - 9.7e-09 35.5 0.0 1.9e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAP88467.1 - 3.6e-08 33.2 0.0 1.1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 GAP88467.1 - 1.6e-07 30.9 0.0 3.9e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAP88467.1 - 3.2e-07 30.0 0.0 3.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAP88467.1 - 0.00061 19.4 0.0 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAP88467.1 - 0.0025 17.9 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNase_PH PF01138.21 GAP88468.1 - 1.3e-24 87.2 0.0 2.5e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAP88468.1 - 2.1e-08 34.0 0.0 4.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 ATP_transf PF09830.9 GAP88469.1 - 2.8e-21 75.4 0.0 5.3e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase Myb_DNA-bind_4 PF13837.6 GAP88470.1 - 0.011 16.1 0.1 0.028 14.8 0.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain C2-set_2 PF08205.12 GAP88470.1 - 0.087 12.9 0.1 0.37 10.9 0.1 2.0 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain GATase PF00117.28 GAP88471.1 - 5e-08 32.9 0.0 7.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAP88471.1 - 0.085 12.6 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase C26 NPP1 PF05630.11 GAP88473.1 - 6.6e-61 205.8 0.2 7.8e-61 205.6 0.2 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) PBSX_XtrA PF17356.2 GAP88473.1 - 0.081 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA Dynactin_p62 PF05502.13 GAP88477.1 - 1.1e-176 588.4 6.4 1.5e-173 578.0 6.4 2.1 1 1 0 1 1 1 1 Dynactin p62 family Ribosomal_S7e PF01251.18 GAP88478.1 - 4.3e-81 271.1 0.1 5e-81 270.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_N PF08240.12 GAP88479.1 - 1.6e-25 89.1 3.7 2.5e-25 88.5 3.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP88479.1 - 5.3e-12 45.8 0.0 1.2e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAP88479.1 - 0.0097 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 GAP88479.1 - 0.067 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1349 PF07081.11 GAP88481.1 - 8.9e-18 64.6 0.0 1.1e-17 64.3 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.16 GAP88482.1 - 7.6e-11 41.5 45.4 7.6e-11 41.5 45.4 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily AA_permease PF00324.21 GAP88483.1 - 1.5e-140 469.0 37.9 1.8e-140 468.7 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP88483.1 - 5.7e-43 147.3 40.0 7.6e-43 146.9 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease CDP-OH_P_transf PF01066.21 GAP88483.1 - 3.3 8.6 7.4 8.4 7.2 1.3 3.7 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase Orai-1 PF07856.12 GAP88483.1 - 4.5 6.9 15.0 0.083 12.6 5.6 2.3 2 0 0 2 2 2 0 Mediator of CRAC channel activity Dynamin_N PF00350.23 GAP88484.1 - 7.6e-13 48.9 0.0 5.1e-12 46.2 0.0 2.4 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAP88484.1 - 2.3e-05 24.4 0.0 0.00021 21.3 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAP88484.1 - 0.00063 20.3 3.7 0.0016 19.0 0.0 3.3 4 0 0 4 4 4 1 ABC transporter RsgA_GTPase PF03193.16 GAP88484.1 - 0.0011 18.9 0.0 0.0033 17.3 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase PIGA PF08288.12 GAP88484.1 - 0.096 13.3 0.1 0.43 11.2 0.0 2.0 2 0 0 2 2 2 0 PIGA (GPI anchor biosynthesis) TSC22 PF01166.18 GAP88484.1 - 0.11 12.9 8.7 0.19 12.1 1.4 4.1 4 0 0 4 4 4 0 TSC-22/dip/bun family TcdB_N PF12918.7 GAP88484.1 - 3.3 8.1 5.7 41 4.6 0.2 4.1 4 0 0 4 4 4 0 TcdB toxin N-terminal helical domain NUDIX_2 PF13869.6 GAP88485.1 - 3.9e-76 254.9 0.0 2.2e-60 203.4 0.0 2.1 1 1 1 2 2 2 2 Nucleotide hydrolase UPF0047 PF01894.17 GAP88486.1 - 1e-36 125.6 0.0 1.5e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.9 GAP88486.1 - 2e-15 56.5 0.6 3.2e-15 55.9 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf-CCHC PF00098.23 GAP88487.1 - 0.00018 21.4 1.6 0.00027 20.8 1.6 1.3 1 0 0 1 1 1 1 Zinc knuckle MPP6 PF10175.9 GAP88487.1 - 0.014 15.9 15.8 28 5.2 15.8 3.0 1 1 0 1 1 1 0 M-phase phosphoprotein 6 NAM-associated PF14303.6 GAP88487.1 - 0.16 12.7 22.0 0.052 14.3 15.1 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Serglycin PF04360.12 GAP88487.1 - 0.19 11.7 3.7 0.35 10.8 3.7 1.5 1 0 0 1 1 1 0 Serglycin AF-4 PF05110.13 GAP88487.1 - 0.74 7.8 25.5 0.13 10.3 21.2 1.8 1 1 0 1 1 1 0 AF-4 proto-oncoprotein CDC45 PF02724.14 GAP88487.1 - 0.84 7.8 9.3 1.2 7.3 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RAP1 PF07218.11 GAP88487.1 - 4.8 5.3 12.1 7.5 4.7 12.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_M16_M PF16187.5 GAP88488.1 - 2.7e-96 322.2 0.3 4.2e-96 321.5 0.3 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 GAP88488.1 - 6.2e-34 117.6 2.2 2.5e-19 70.0 0.0 4.4 6 0 0 6 6 6 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 GAP88488.1 - 9.6e-31 106.8 3.0 9.9e-31 106.7 0.4 2.4 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) UCH PF00443.29 GAP88489.1 - 1.6e-71 240.8 0.0 2.3e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAP88489.1 - 2.5e-13 50.4 0.0 9.6e-06 25.4 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 GAP88489.1 - 3.3e-05 24.4 0.0 0.00012 22.6 0.0 2.1 1 0 0 1 1 1 1 DUSP domain ubiquitin PF00240.23 GAP88489.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family PDEase_I PF00233.19 GAP88490.1 - 1.3e-67 228.0 0.0 2e-67 227.4 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pkinase PF00069.25 GAP88491.1 - 8.4e-58 195.8 0.0 1.1e-57 195.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP88491.1 - 2.5e-20 72.9 0.0 4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP88491.1 - 7.1e-07 28.8 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAP88491.1 - 8.1e-06 25.0 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAP88491.1 - 0.00028 20.3 0.1 0.00052 19.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAP88491.1 - 0.0047 16.6 0.4 0.0095 15.5 0.1 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 GAP88491.1 - 0.0048 16.9 0.3 0.16 11.9 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAP88491.1 - 0.012 14.4 0.0 0.028 13.2 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 GAP88491.1 - 0.22 10.5 0.1 0.36 9.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RabGAP-TBC PF00566.18 GAP88492.1 - 6.6e-25 88.0 2.1 1.8e-24 86.6 2.1 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain KH_1 PF00013.29 GAP88494.1 - 3.7e-41 138.8 8.9 2.7e-16 59.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAP88494.1 - 4.5e-10 39.2 8.4 0.0094 15.8 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GAP88494.1 - 7.2e-08 32.2 4.0 0.053 13.4 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 GAP88494.1 - 5.1e-05 23.3 4.9 0.25 11.5 0.0 3.3 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.19 GAP88494.1 - 0.09 12.5 0.3 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 dUTPase UAA PF08449.11 GAP88495.1 - 9.8e-40 136.6 8.5 1.3e-39 136.2 8.5 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 GAP88495.1 - 1.2e-06 28.8 26.7 7.7e-05 22.9 10.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 GAP88495.1 - 0.00029 20.1 1.2 0.0087 15.3 0.1 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 GAP88495.1 - 0.065 12.6 10.6 0.92 8.8 3.2 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family SPW PF03779.14 GAP88495.1 - 3.3 7.4 8.4 0.77 9.4 0.6 3.3 3 0 0 3 3 3 0 SPW repeat DSPc PF00782.20 GAP88496.1 - 3.6e-23 81.8 0.0 1.2e-19 70.5 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 GAP88496.1 - 0.03 14.6 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 GAP88496.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTS_2-RNA PF01885.16 GAP88498.1 - 2.4e-29 102.6 0.0 3.2e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RLL PF10036.9 GAP88499.1 - 0.002 18.1 0.2 0.004 17.1 0.2 1.5 1 1 0 1 1 1 1 RNA transcription, translation and transport factor protein ResB PF05140.14 GAP88499.1 - 4.6 5.9 10.0 0.57 8.9 3.6 2.0 2 0 0 2 2 2 0 ResB-like family Efg1 PF10153.9 GAP88500.1 - 1.2e-31 109.4 11.0 1.2e-31 109.4 11.0 1.8 2 0 0 2 2 2 1 rRNA-processing protein Efg1 She9_MDM33 PF05546.11 GAP88500.1 - 0.034 14.0 4.2 0.053 13.3 4.2 1.2 1 0 0 1 1 1 0 She9 / Mdm33 family zinc_ribbon_16 PF17034.5 GAP88501.1 - 9.6e-18 64.6 7.4 2.4e-17 63.3 7.4 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 GAP88501.1 - 1.3e-06 27.9 4.1 1.3e-06 27.9 4.1 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type DUF5327 PF17261.2 GAP88502.1 - 0.053 14.3 0.1 0.053 14.3 0.1 1.9 3 0 0 3 3 3 0 Family of unknown function (DUF5327) GRP PF07172.11 GAP88502.1 - 2 9.2 21.5 0.07 13.8 6.7 3.0 3 0 0 3 3 3 0 Glycine rich protein family Glucosamine_iso PF01182.20 GAP88505.1 - 4.8e-68 229.4 0.0 5.5e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hydrolase_6 PF13344.6 GAP88506.1 - 2.1e-27 95.1 0.0 3.5e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP88506.1 - 2e-16 59.8 0.0 3.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAP88506.1 - 2.4e-09 37.8 0.0 0.0064 16.8 0.1 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAP88506.1 - 2e-05 24.8 0.4 0.053 13.6 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAP88506.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 GAP88506.1 - 0.22 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) LAGLIDADG_3 PF14528.6 GAP88506.1 - 0.23 11.8 0.5 0.44 10.9 0.1 1.8 2 0 0 2 2 2 0 LAGLIDADG-like domain CorA PF01544.18 GAP88507.1 - 1.9e-08 34.0 0.0 1.9e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DHFR_1 PF00186.19 GAP88509.1 - 5.3e-21 75.0 0.0 8.9e-19 67.8 0.0 2.9 2 1 0 2 2 2 1 Dihydrofolate reductase Ubiq_cyt_C_chap PF03981.12 GAP88510.1 - 1.5e-37 128.9 0.6 2.4e-37 128.2 0.6 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DNA_pol_A_exoN PF18305.1 GAP88510.1 - 0.051 13.9 0.3 4.1 7.8 0.1 3.2 2 1 1 3 3 3 0 3' to 5' exonuclease C-terminal domain ketoacyl-synt PF00109.26 GAP88511.1 - 1.2e-59 201.9 2.4 1.5e-58 198.4 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAP88511.1 - 9.9e-35 119.1 2.4 1.7e-34 118.4 1.9 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 GAP88511.1 - 3.5e-06 26.6 0.1 3e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAP88511.1 - 0.0036 16.9 4.6 0.0097 15.6 0.4 3.1 2 2 1 3 3 3 1 Thiolase, C-terminal domain KAsynt_C_assoc PF16197.5 GAP88511.1 - 0.037 14.5 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension OPT PF03169.15 GAP88512.1 - 3.3e-176 587.6 53.9 3.8e-176 587.4 53.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AMPK1_CBM PF16561.5 GAP88513.1 - 0.0005 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Iwr1 PF08574.10 GAP88514.1 - 1.1e-16 61.6 10.7 1.1e-16 61.6 10.7 3.6 4 1 0 4 4 4 1 Transcription factor Iwr1 BLOC1S3 PF15753.5 GAP88514.1 - 1.8 8.6 5.6 2.8 8.0 4.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 His_Phos_1 PF00300.22 GAP88516.1 - 6.4e-19 68.4 0.0 2.9e-18 66.3 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Fungus-induced PF10917.8 GAP88517.1 - 0.66 10.3 12.5 5 7.5 1.3 2.6 2 1 0 2 2 2 0 Fungus-induced protein DEAD PF00270.29 GAP88518.1 - 2.5e-29 102.3 0.0 3.8e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP88518.1 - 3.8e-19 69.1 0.0 1.2e-18 67.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP88518.1 - 2.5e-05 24.3 0.0 6.6e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 GAP88518.1 - 0.1 12.9 0.0 24 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain zf-MYND PF01753.18 GAP88519.1 - 5.7e-08 32.7 16.8 9.6e-08 32.0 16.8 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 GAP88519.1 - 0.32 11.1 8.2 0.68 10.1 8.2 1.6 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 YL1 PF05764.13 GAP88520.1 - 1.3e-67 228.5 32.5 1.3e-67 228.5 32.5 2.1 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 GAP88520.1 - 2.6e-16 59.1 1.4 2.7e-15 55.8 0.8 2.3 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain GOLD_2 PF13897.6 GAP88520.1 - 0.098 13.1 2.1 0.31 11.5 2.1 1.8 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF2423 PF10338.9 GAP88521.1 - 1.4e-18 66.8 4.1 1.4e-18 66.8 4.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) PINIT PF14324.6 GAP88522.1 - 3.2e-41 141.1 0.0 5.4e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 GAP88522.1 - 4.2e-21 74.4 6.1 7.2e-21 73.7 6.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 GAP88522.1 - 9e-06 25.4 1.4 2.2e-05 24.2 1.4 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 GAP88522.1 - 0.00014 21.5 0.2 0.00026 20.7 0.2 1.5 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 GAP88522.1 - 0.0018 18.3 2.5 0.0069 16.4 2.5 2.0 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger zf-C3HC4_2 PF13923.6 GAP88522.1 - 0.7 9.8 5.0 1.4 8.8 5.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TRAPP PF04051.16 GAP88523.1 - 8.8e-41 139.0 0.0 6.6e-40 136.2 0.0 1.9 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Ldh_1_C PF02866.18 GAP88524.1 - 1.9e-46 158.1 0.0 2.6e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAP88524.1 - 1.7e-43 148.1 0.2 2.3e-43 147.7 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAP88524.1 - 0.023 13.7 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L28e PF01778.17 GAP88525.1 - 2.5e-34 118.5 1.0 3e-34 118.2 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.10 GAP88526.1 - 1.1e-46 157.3 0.0 1.2e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) FA_hydroxylase PF04116.13 GAP88527.1 - 7.9e-23 81.3 15.7 7.9e-23 81.3 15.7 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3328 PF11807.8 GAP88528.1 - 6.7e-53 179.7 0.0 1.1e-52 179.0 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Tup_N PF08581.10 GAP88529.1 - 2.5e-17 63.0 10.6 9e-17 61.2 10.6 1.7 1 1 0 1 1 1 1 Tup N-terminal Gal-3-0_sulfotr PF06990.11 GAP88529.1 - 0.14 11.0 0.3 0.16 10.8 0.3 1.1 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase COMP PF11598.8 GAP88529.1 - 0.45 11.0 5.4 2.1 8.9 0.5 2.6 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein DUF406 PF04175.12 GAP88530.1 - 0.016 15.7 0.0 9.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF406) CAP_N PF01213.19 GAP88530.1 - 0.22 11.0 2.3 0.2 11.1 0.9 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Cutinase PF01083.22 GAP88532.1 - 1.4e-29 103.3 0.5 2.2e-29 102.6 0.5 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAP88532.1 - 0.00077 19.1 0.2 0.0012 18.5 0.2 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 GAP88532.1 - 0.0069 16.2 0.0 0.017 14.9 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 GAP88532.1 - 0.017 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) VirJ PF06057.11 GAP88532.1 - 0.085 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_3 PF07859.13 GAP88532.1 - 0.18 11.6 0.1 0.18 11.6 0.1 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold HET PF06985.11 GAP88534.1 - 1.4e-19 70.9 0.0 3.5e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OGFr_N PF04664.13 GAP88535.1 - 4.9e-14 52.4 0.0 8.7e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region DUF1289 PF06945.13 GAP88535.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) adh_short PF00106.25 GAP88536.1 - 6.5e-43 146.5 0.0 1e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88536.1 - 5.1e-31 108.0 0.0 6.3e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88536.1 - 2.8e-08 33.9 0.0 4.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP88536.1 - 1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAP88536.1 - 0.0013 18.2 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 GAP88536.1 - 0.0061 15.7 0.0 0.021 14.0 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.8 GAP88536.1 - 0.05 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.26 GAP88536.1 - 0.055 13.5 0.2 9 6.3 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 GAP88536.1 - 0.055 13.4 0.3 0.08 12.8 0.3 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Ras PF00071.22 GAP88538.1 - 8.9e-39 132.7 0.0 1.4e-24 86.6 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAP88538.1 - 1.3e-11 44.7 0.1 2.4e-11 43.9 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAP88538.1 - 0.0024 17.9 0.0 0.0036 17.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 GAP88538.1 - 0.0026 17.2 0.0 0.0098 15.4 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAP88538.1 - 0.047 13.2 0.0 0.68 9.4 0.0 2.3 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain PRK PF00485.18 GAP88538.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Asp PF00026.23 GAP88539.1 - 1.8e-50 172.1 0.0 2.3e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP88539.1 - 0.00015 22.1 0.1 0.0012 19.1 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAP88539.1 - 0.0077 16.9 0.0 1.4 9.7 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease Sporozoite_P67 PF05642.11 GAP88540.1 - 7.6 4.5 7.1 8 4.4 7.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AMMECR1 PF01871.17 GAP88541.1 - 7.1e-47 159.1 0.0 1e-46 158.6 0.0 1.3 1 1 0 1 1 1 1 AMMECR1 DUF455 PF04305.14 GAP88542.1 - 1.8e-98 329.0 0.1 2.3e-98 328.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 GAP88542.1 - 3.5e-06 26.9 0.0 6.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 GAP88542.1 - 0.00047 20.1 0.0 0.0014 18.5 0.0 1.9 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Clc-like PF07062.12 GAP88543.1 - 0.61 9.5 3.3 0.33 10.4 0.8 1.7 1 1 1 2 2 2 0 Clc-like Piwi PF02171.17 GAP88545.1 - 4.4e-80 269.2 0.0 7.4e-80 268.4 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 GAP88545.1 - 1.1e-17 64.9 0.0 3e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 GAP88545.1 - 1.1e-15 57.0 0.0 4.9e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 GAP88545.1 - 9.3e-12 45.1 0.0 1.9e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 GAP88545.1 - 4.4e-10 39.5 0.0 9.3e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 GAP88545.1 - 2e-08 34.4 0.0 5.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute Suf PF05843.14 GAP88546.1 - 8.5e-79 265.6 1.0 9.8e-77 258.8 0.1 3.1 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 GAP88546.1 - 0.0046 16.1 2.7 0.01 15.0 0.1 2.7 2 1 2 4 4 4 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 GAP88546.1 - 0.012 16.3 8.5 0.33 11.9 0.0 5.9 5 2 3 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAP88546.1 - 0.062 13.8 0.3 18 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Voldacs PF03517.13 GAP88546.1 - 4.8 7.3 6.6 2.3 8.3 1.1 2.4 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling TPR_16 PF13432.6 GAP88546.1 - 6.3 7.5 8.3 2.6 8.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Amidohydro_2 PF04909.14 GAP88547.1 - 2.1e-26 93.4 0.0 2.8e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Abhydrolase_3 PF07859.13 GAP88548.1 - 5.5e-22 78.7 0.2 7.8e-22 78.2 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP88548.1 - 1.9e-07 30.3 0.0 2.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Lipoxygenase PF00305.19 GAP88549.1 - 2.4e-21 75.9 0.0 3.4e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 Lipoxygenase ASF1_hist_chap PF04729.13 GAP88550.1 - 8.6e-72 240.1 0.0 1.2e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone FMN_dh PF01070.18 GAP88551.1 - 4e-25 88.6 0.8 5.4e-25 88.1 0.8 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAP88551.1 - 8.3e-20 70.7 0.0 1.4e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FMN_dh PF01070.18 GAP88552.1 - 2.3e-61 207.8 1.3 2.7e-61 207.5 1.3 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 GAP88552.1 - 7.1e-06 25.4 1.0 1.7e-05 24.2 0.1 1.8 1 1 1 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 GAP88552.1 - 0.00052 19.5 0.1 0.00074 19.0 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAP88552.1 - 0.001 18.1 0.4 0.0049 15.9 0.4 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 GAP88552.1 - 0.03 13.7 0.2 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Egh16-like PF11327.8 GAP88553.1 - 4.7e-52 177.1 8.1 7.1e-52 176.5 8.1 1.3 1 0 0 1 1 1 1 Egh16-like virulence factor I-set PF07679.16 GAP88553.1 - 0.03 14.4 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Ig_2 PF13895.6 GAP88553.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Alginate_lyase PF05426.12 GAP88555.1 - 3.1e-21 76.1 0.6 6.9e-21 75.0 0.6 1.5 1 1 0 1 1 1 1 Alginate lyase Glyco_hydro_28 PF00295.17 GAP88556.1 - 1.7e-12 47.1 1.4 2.8e-12 46.4 1.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 GAP88556.1 - 0.00036 20.4 12.5 0.0023 17.8 5.1 2.9 1 1 1 2 2 2 2 Right handed beta helix region Fungal_trans PF04082.18 GAP88557.1 - 2.8e-11 42.9 3.3 2.1e-10 40.1 3.3 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP88557.1 - 1e-08 35.2 14.4 2.3e-08 34.0 14.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAP88558.1 - 2.2e-28 99.2 32.5 2.2e-28 99.2 32.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAP88558.1 - 1.4e-07 31.2 8.6 1.4e-07 31.2 8.6 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Glyco_hydro_88 PF07470.13 GAP88559.1 - 4.4e-15 55.6 0.5 5.7e-15 55.2 0.5 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF4550 PF15084.6 GAP88559.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) Alginate_lyase PF05426.12 GAP88560.1 - 8.1e-08 32.1 2.5 3.6e-07 30.0 2.5 1.8 1 1 0 1 1 1 1 Alginate lyase DUF1459 PF07312.11 GAP88560.1 - 0.21 11.8 2.6 2.4 8.4 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) GMC_oxred_N PF00732.19 GAP88561.1 - 1.3e-27 96.9 0.0 1.8e-19 70.2 0.0 3.2 3 0 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP88561.1 - 1.1e-26 94.1 0.1 1.9e-26 93.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAP88561.1 - 2.5e-06 27.0 0.1 2.3e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP88561.1 - 0.00021 21.5 0.7 0.00059 20.0 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAP88561.1 - 0.0076 15.4 0.5 0.014 14.5 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 GAP88561.1 - 0.015 15.0 0.7 0.027 14.1 0.7 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 GAP88561.1 - 0.017 14.4 0.1 6.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP88561.1 - 0.027 13.2 0.2 0.08 11.6 0.3 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 GAP88561.1 - 0.03 13.7 0.1 0.05 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 GAP88561.1 - 0.034 13.7 0.9 0.28 10.7 0.3 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.21 GAP88561.1 - 0.042 13.2 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 GAP88561.1 - 0.05 12.7 0.6 0.089 11.9 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 GAP88561.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein PTR2 PF00854.21 GAP88562.1 - 7.8e-73 245.6 4.3 1.3e-72 244.9 4.3 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 GAP88562.1 - 1e-06 27.9 30.3 0.00063 18.8 29.9 4.1 2 1 0 2 2 2 1 Major Facilitator Superfamily SelP_N PF04592.14 GAP88563.1 - 1.5 8.2 6.8 2.1 7.7 6.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TPP_enzyme_N PF02776.18 GAP88564.1 - 3.9e-34 117.7 0.2 6.6e-34 117.0 0.2 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAP88564.1 - 1.8e-18 66.6 0.0 7e-18 64.7 0.0 2.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GAP88564.1 - 5.2e-17 62.0 0.3 4.6e-16 59.0 0.1 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RasGAP PF00616.19 GAP88565.1 - 1.7e-55 188.0 0.2 9e-55 185.6 0.0 2.3 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 GAP88565.1 - 1.8e-29 102.6 4.6 1.8e-29 102.6 4.6 2.4 2 0 0 2 2 2 1 RasGAP C-terminus RtcB PF01139.17 GAP88565.1 - 0.35 10.0 3.2 0.19 10.9 0.3 1.8 2 0 0 2 2 2 0 tRNA-splicing ligase RtcB Ank_2 PF12796.7 GAP88566.1 - 2.7e-82 271.4 49.5 3.5e-13 50.0 0.0 9.0 3 1 9 12 12 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88566.1 - 4.4e-76 250.3 35.4 9.1e-12 45.3 0.0 14.2 3 1 11 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.30 GAP88566.1 - 1e-72 237.6 62.1 5.2e-06 26.7 0.1 15.2 16 0 0 16 16 14 14 Ankyrin repeat Ank_5 PF13857.6 GAP88566.1 - 2.9e-59 196.3 29.5 2.4e-10 40.4 0.3 11.0 5 3 4 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88566.1 - 1.9e-41 135.3 18.7 0.0016 18.8 0.0 17.5 16 3 0 16 16 15 7 Ankyrin repeat NACHT PF05729.12 GAP88566.1 - 3.2e-08 33.7 0.0 6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF4988 PF16378.5 GAP88566.1 - 1.9e-07 30.9 0.0 0.44 10.2 0.0 5.7 1 1 3 5 5 5 2 Domain of unknown function DUF4147 PF13660.6 GAP88566.1 - 2.1e-05 24.2 17.5 0.33 10.5 0.2 8.2 5 2 5 10 10 10 3 Domain of unknown function (DUF4147) AAA_22 PF13401.6 GAP88566.1 - 0.0017 18.6 0.0 0.0058 16.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF3885 PF13021.6 GAP88566.1 - 0.0038 17.3 0.3 1.1e+02 3.0 0.0 5.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3885) RNA_helicase PF00910.22 GAP88566.1 - 0.0084 16.5 0.0 0.027 14.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 GAP88566.1 - 0.011 16.2 0.0 0.035 14.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 GAP88566.1 - 0.031 14.4 0.0 0.08 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 GAP88566.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 GAP88566.1 - 0.055 14.0 0.0 0.23 12.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 GAP88566.1 - 0.1 12.7 0.0 0.6 10.2 0.0 2.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase CholecysA-Rec_N PF09193.10 GAP88566.1 - 1.2 9.2 7.4 27 4.9 0.3 4.6 4 0 0 4 4 4 0 Cholecystokinin A receptor, N-terminal Glyco_hydro_cc PF11790.8 GAP88567.1 - 9.5e-52 175.9 0.0 1.2e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core GST_N_2 PF13409.6 GAP88568.1 - 0.00017 21.8 0.0 0.00043 20.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAP88568.1 - 0.0036 17.7 0.0 0.088 13.2 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP88568.1 - 0.016 15.2 2.4 0.029 14.4 0.5 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain NYD-SP28 PF14772.6 GAP88569.1 - 1.3 9.1 9.1 2.2 8.4 9.1 1.3 1 0 0 1 1 1 0 Sperm tail COesterase PF00135.28 GAP88570.1 - 1.3e-78 265.1 0.1 2.2e-68 231.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP88570.1 - 0.0036 17.2 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 GAP88571.1 - 3.7e-24 85.3 37.1 3.4e-23 82.2 27.9 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP88571.1 - 5.9e-09 35.3 0.8 5.9e-09 35.3 0.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter NMD3 PF04981.13 GAP88573.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 NMD3 family Acetyltransf_1 PF00583.25 GAP88574.1 - 1.9e-08 34.6 0.0 5.7e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 GAP88574.1 - 6.6e-08 33.3 0.0 1.3e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP88574.1 - 8e-05 23.0 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAP88574.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP88574.1 - 0.027 14.5 0.1 0.085 12.8 0.1 1.9 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 GAP88574.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF373 PF04123.13 GAP88575.1 - 0.021 14.3 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DASH_Spc34 PF08657.10 GAP88577.1 - 1.7e-21 77.2 0.2 1.9e-21 77.0 0.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 SGT1 PF07093.11 GAP88577.1 - 0.029 12.8 0.8 0.029 12.8 0.8 1.0 1 0 0 1 1 1 0 SGT1 protein Uds1 PF15456.6 GAP88577.1 - 0.11 12.6 3.3 0.16 12.1 3.3 1.3 1 1 0 1 1 1 0 Up-regulated During Septation DASH_Spc19 PF08287.11 GAP88577.1 - 0.15 12.0 3.2 0.18 11.7 3.2 1.2 1 0 0 1 1 1 0 Spc19 RRN3 PF05327.11 GAP88577.1 - 0.16 10.5 1.8 0.15 10.6 1.8 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CRA PF06589.11 GAP88577.1 - 0.45 10.6 1.6 0.58 10.3 1.6 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) NOA36 PF06524.12 GAP88577.1 - 1.7 7.9 7.1 2.1 7.6 7.1 1.1 1 0 0 1 1 1 0 NOA36 protein DASH_Spc34 PF08657.10 GAP88578.1 - 1.1e-25 90.9 0.8 3.4e-24 86.0 0.3 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 PSCyt3 PF07627.11 GAP88578.1 - 0.026 14.8 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) CAP_N PF01213.19 GAP88578.1 - 0.075 12.5 1.6 0.079 12.4 1.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GAP88578.1 - 9.7 6.3 8.8 18 5.4 5.2 2.0 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 TFIID_20kDa PF03847.13 GAP88580.1 - 1.1e-20 73.8 0.0 1.8e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 GAP88580.1 - 0.0057 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Rpn3_C PF08375.11 GAP88581.1 - 5.4e-26 90.8 1.0 1.6e-25 89.3 1.0 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 GAP88581.1 - 1e-20 74.2 0.2 3.9e-20 72.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 GAP88581.1 - 0.011 15.8 0.1 0.046 13.9 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP88581.1 - 2.9 8.2 5.1 6.4 7.1 0.8 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MOZ_SAS PF01853.18 GAP88582.1 - 3.6e-51 173.4 0.0 5.9e-34 117.3 0.0 2.3 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 GAP88582.1 - 4.2e-07 29.5 6.9 3.7e-06 26.4 6.9 2.3 1 1 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 GAP88582.1 - 0.17 12.3 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FSA_C PF10479.9 GAP88582.1 - 8.7 4.3 17.4 13 3.8 17.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus ATP-synt_C PF00137.21 GAP88583.1 - 1.1e-10 41.6 12.5 1.1e-10 41.6 12.5 2.2 2 1 0 2 2 2 1 ATP synthase subunit C Hanta_nucleocap PF00846.18 GAP88583.1 - 0.03 12.8 0.1 0.037 12.5 0.1 1.0 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein zf-H2C2_2 PF13465.6 GAP88586.1 - 0.0018 18.6 0.3 0.0018 18.6 0.3 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 GAP88586.1 - 0.0096 16.3 21.9 0.043 14.3 0.8 4.8 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-CHCC PF10276.9 GAP88586.1 - 0.12 12.4 3.2 4.8 7.3 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger domain HypA PF01155.19 GAP88586.1 - 0.24 11.4 1.6 0.47 10.5 1.6 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_recom PF13408.6 GAP88586.1 - 4.6 7.8 6.5 24 5.5 0.4 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2H2_4 PF13894.6 GAP88586.1 - 9.2 7.4 26.1 0.2 12.6 1.4 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger DSPc PF00782.20 GAP88587.1 - 8.9e-15 54.7 0.3 6.5e-06 26.0 0.2 3.1 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 GAP88587.1 - 0.00014 22.1 0.0 0.00024 21.4 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Vfa1 PF08432.10 GAP88589.1 - 3.5e-57 193.7 28.1 7.4e-57 192.6 28.1 1.5 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Atrophin-1 PF03154.15 GAP88589.1 - 0.0013 17.1 20.9 0.0018 16.7 20.9 1.3 1 0 0 1 1 1 1 Atrophin-1 family DDHD PF02862.17 GAP88589.1 - 0.067 13.4 3.8 0.076 13.2 3.8 1.3 1 0 0 1 1 1 0 DDHD domain SRP-alpha_N PF04086.13 GAP88589.1 - 0.072 13.0 23.1 0.092 12.7 23.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PPL5 PF18168.1 GAP88589.1 - 0.14 11.4 10.6 0.18 11.0 10.6 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF913 PF06025.12 GAP88589.1 - 0.21 10.5 6.3 0.22 10.5 6.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIP PF07454.11 GAP88589.1 - 0.29 10.6 14.1 0.42 10.0 14.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 GAP88589.1 - 0.59 9.9 20.4 0.84 9.4 20.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 GAP88589.1 - 0.59 9.5 17.2 0.76 9.1 17.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 GAP88589.1 - 0.72 8.6 18.7 0.8 8.4 18.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIIAH PF12685.7 GAP88589.1 - 0.79 9.5 17.0 1.2 8.9 17.0 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF908 PF06012.12 GAP88589.1 - 0.98 8.8 8.0 1.2 8.5 8.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SID-1_RNA_chan PF13965.6 GAP88589.1 - 1 7.7 5.5 1.7 7.0 5.5 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 FAM60A PF15396.6 GAP88589.1 - 1.8 8.5 18.3 4.6 7.2 16.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Raftlin PF15250.6 GAP88589.1 - 2.4 6.8 12.2 2.8 6.6 12.2 1.1 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 GAP88589.1 - 3.2 5.9 30.7 4 5.6 30.7 1.0 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.8 GAP88589.1 - 4.6 6.0 26.8 5.8 5.7 26.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GCD14 PF08704.10 GAP88589.1 - 4.7 6.8 8.3 6.7 6.3 8.3 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit EMC3_TMCO1 PF01956.16 GAP88589.1 - 4.8 6.9 8.0 7.8 6.2 8.0 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Serinc PF03348.15 GAP88589.1 - 5.9 5.7 5.3 6.9 5.5 5.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) GREB1 PF15782.5 GAP88589.1 - 6.1 3.8 6.8 7 3.6 6.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 GAP88589.1 - 7.9 5.1 18.1 9.7 4.8 18.1 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 GAP88589.1 - 8.6 5.5 12.0 12 5.0 12.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 GAP88589.1 - 9.9 5.1 17.2 12 4.8 17.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Rtt106 PF08512.12 GAP88590.1 - 5.6e-30 103.6 0.0 5.4e-29 100.5 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 GAP88590.1 - 1.2e-05 25.4 0.0 8.2e-05 22.6 0.0 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain Asp PF00026.23 GAP88591.1 - 6e-30 104.7 0.0 8.9e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP88591.1 - 3.7e-05 24.0 1.2 0.0012 19.2 1.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal p450 PF00067.22 GAP88592.1 - 3.1e-38 131.7 0.0 3.9e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 XPG_I PF00867.18 GAP88593.1 - 1.9e-08 34.5 0.1 5.6e-08 33.0 0.1 1.7 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 GAP88593.1 - 0.00043 20.7 0.0 0.00059 20.3 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain NACHT PF05729.12 GAP88593.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 NACHT domain VEFS-Box PF09733.9 GAP88596.1 - 7.3e-07 29.1 0.2 2.1e-06 27.6 0.2 1.7 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.29 GAP88596.1 - 0.001 18.9 7.4 0.001 18.9 7.4 2.1 2 0 0 2 2 2 1 PHD-finger zf-C2HE PF16278.5 GAP88596.1 - 0.094 13.2 2.3 0.67 10.4 0.1 2.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DNA_ligase_ZBD PF03119.16 GAP88596.1 - 0.21 11.6 5.1 0.74 9.9 5.1 2.0 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-tcix PF14952.6 GAP88596.1 - 0.29 10.8 4.3 0.092 12.4 0.5 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Sugar_tr PF00083.24 GAP88597.1 - 4.1e-70 236.9 22.2 4.7e-70 236.7 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP88597.1 - 1.4e-12 47.2 24.7 2.3e-12 46.6 24.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF382 PF04037.13 GAP88598.1 - 8.9e-60 200.4 1.4 8.9e-60 200.4 1.4 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 GAP88598.1 - 3.6e-18 65.1 3.5 8.1e-18 64.0 3.5 1.6 1 0 0 1 1 1 1 PSP TPT PF03151.16 GAP88599.1 - 1.7e-56 191.7 9.9 2e-56 191.5 9.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 GAP88599.1 - 8.5e-08 32.5 26.3 3.2e-05 24.1 8.4 3.0 2 1 0 2 2 2 2 EamA-like transporter family PSII PF00421.19 GAP88599.1 - 0.026 13.2 0.2 0.11 11.1 0.0 1.9 2 0 0 2 2 2 0 Photosystem II protein M-factor PF03855.13 GAP88599.1 - 0.06 13.5 0.7 0.16 12.1 0.7 1.7 1 0 0 1 1 1 0 M-factor UAA PF08449.11 GAP88599.1 - 0.14 11.3 15.2 0.68 9.1 15.2 1.9 1 1 0 1 1 1 0 UAA transporter family ATP-synt_ab PF00006.25 GAP88600.1 - 6.5e-59 199.1 0.0 1.1e-58 198.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 GAP88600.1 - 1.7e-22 79.7 0.3 8.7e-22 77.4 0.2 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 GAP88600.1 - 0.012 16.0 0.0 0.48 10.9 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 GAP88600.1 - 0.015 15.2 0.6 0.031 14.2 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 GAP88600.1 - 0.018 14.2 0.2 0.084 12.0 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 GAP88600.1 - 0.029 13.7 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 GAP88600.1 - 0.042 13.8 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 GAP88600.1 - 0.042 14.2 1.2 0.5 10.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAP88600.1 - 0.054 13.4 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain T3SS_ATPase_C PF18269.1 GAP88600.1 - 0.062 13.2 0.4 0.32 10.9 0.4 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RNA_helicase PF00910.22 GAP88600.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 GAP88600.1 - 0.13 12.7 0.4 0.42 11.0 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 GAP88600.1 - 0.18 11.8 0.1 0.46 10.5 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cu-oxidase_3 PF07732.15 GAP88601.1 - 7.6e-43 145.3 7.9 1.8e-41 140.9 1.3 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 GAP88601.1 - 4e-42 144.0 4.6 1.8e-37 128.9 0.4 2.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAP88601.1 - 8.8e-42 142.1 5.3 2.3e-37 127.8 0.0 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 GAP88601.1 - 0.0017 18.4 0.0 21 5.3 0.0 3.7 3 0 0 3 3 3 2 Cupredoxin-like domain FTR1 PF03239.14 GAP88602.1 - 7.9e-79 265.0 12.7 9.7e-79 264.7 12.7 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family Snf7 PF03357.21 GAP88604.1 - 7.6e-19 68.0 0.9 7.6e-19 68.0 0.9 1.9 2 0 0 2 2 2 1 Snf7 Ribosomal_L37 PF08561.10 GAP88604.1 - 5.4 7.6 6.1 2.2 8.9 2.9 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 CS PF04969.16 GAP88605.1 - 1.5e-07 32.3 0.1 2.4e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF4202 PF13875.6 GAP88605.1 - 0.074 12.9 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) gpW PF02831.15 GAP88608.1 - 0.26 11.2 1.1 1.1 9.2 0.2 2.6 3 0 0 3 3 3 0 gpW PIG-H PF10181.9 GAP88609.1 - 1.8e-23 82.2 0.1 2.5e-23 81.7 0.1 1.2 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.20 GAP88610.1 - 4.5e-34 117.1 0.0 5.8e-33 113.6 0.0 2.7 2 1 1 3 3 3 1 tRNA pseudouridine synthase Ras PF00071.22 GAP88611.1 - 2.6e-20 72.7 0.0 4.1e-20 72.0 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 GAP88611.1 - 1.3e-08 35.1 0.0 2.5e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP88611.1 - 0.00049 19.6 0.2 0.79 9.2 0.1 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family ABC_tran PF00005.27 GAP88611.1 - 0.0034 17.9 0.0 0.0046 17.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 GAP88611.1 - 0.0099 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DLIC PF05783.11 GAP88611.1 - 0.017 14.0 0.4 0.057 12.3 0.1 1.7 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 GAP88611.1 - 0.017 14.9 0.0 0.05 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAP88611.1 - 0.021 15.2 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 GAP88611.1 - 0.034 14.2 0.0 0.07 13.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 GAP88611.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 GAP88611.1 - 0.068 13.1 0.2 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 GAP88611.1 - 0.074 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP88611.1 - 0.088 13.1 0.1 0.2 11.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 GAP88611.1 - 0.12 12.2 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 GAP88611.1 - 0.18 11.6 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_pol_Rpb4 PF03874.16 GAP88612.1 - 1.5e-15 57.6 0.0 1.8e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 RhlB PF12300.8 GAP88614.1 - 0.41 10.8 14.7 0.55 10.3 14.7 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB ORC6 PF05460.13 GAP88615.1 - 1.5e-30 106.7 7.1 2.1e-30 106.2 7.1 1.5 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.6 GAP88616.1 - 1.9e-08 33.6 0.1 0.011 15.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 GAP88616.1 - 9.1e-08 32.5 0.3 2e-07 31.4 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 GAP88616.1 - 0.0025 17.2 0.1 0.0094 15.4 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 GAP88616.1 - 0.0077 15.7 0.2 0.34 10.6 0.0 2.6 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 GAP88616.1 - 0.058 13.2 0.1 0.81 9.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Met_10 PF02475.16 GAP88617.1 - 0.00033 20.4 0.0 0.0034 17.2 0.0 2.2 2 0 0 2 2 2 1 Met-10+ like-protein DUF3439 PF11921.8 GAP88617.1 - 0.037 14.0 5.2 0.06 13.3 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 GAP88617.1 - 0.041 13.9 8.0 0.084 12.9 8.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 GAP88617.1 - 0.62 8.2 9.8 0.83 7.8 9.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.12 GAP88617.1 - 2.3 6.1 4.8 3 5.7 4.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ribosomal_S13 PF00416.22 GAP88619.1 - 4.4e-52 175.8 0.7 5.1e-52 175.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 GAP88619.1 - 0.0049 15.7 0.0 0.0051 15.6 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) H2TH PF06831.14 GAP88619.1 - 0.018 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain HHH_5 PF14520.6 GAP88619.1 - 0.068 13.8 0.2 0.2 12.3 0.1 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain IMS_HHH PF11798.8 GAP88619.1 - 0.076 13.4 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif S36_mt PF10937.8 GAP88620.1 - 1.4e-37 129.8 2.6 3.3e-37 128.6 2.6 1.5 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial PNK3P PF08645.11 GAP88621.1 - 1.1e-53 181.2 0.0 1.7e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 GAP88621.1 - 3.3e-28 98.7 0.0 6.7e-26 91.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAP88621.1 - 0.023 14.1 0.2 4.8 6.5 0.1 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 GAP88621.1 - 0.025 14.3 0.0 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 GAP88621.1 - 0.029 14.7 0.0 0.22 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 GAP88621.1 - 0.039 13.9 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain LPD7 PF18821.1 GAP88621.1 - 0.04 14.0 0.2 16 5.7 0.0 3.2 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 7 AAA_11 PF13086.6 GAP88621.1 - 0.049 13.4 0.1 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 GAP88621.1 - 0.058 12.4 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 GAP88621.1 - 0.19 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAP88621.1 - 0.2 12.2 0.1 1 9.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain XPA_C PF05181.12 GAP88622.1 - 2.1e-25 88.4 1.3 3.9e-25 87.6 1.3 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 GAP88622.1 - 0.01 15.9 3.7 0.01 15.9 3.7 2.2 3 0 0 3 3 3 0 XPA protein N-terminal ArfGap PF01412.18 GAP88622.1 - 0.036 14.1 0.3 0.098 12.7 0.3 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf YhfH PF14149.6 GAP88622.1 - 0.14 12.1 2.3 0.76 9.8 0.5 2.6 2 0 0 2 2 2 0 YhfH-like protein Etmic-2 PF06670.11 GAP88622.1 - 0.81 8.6 3.2 1.2 8.0 3.2 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 Pkinase PF00069.25 GAP88623.1 - 4.7e-06 26.2 0.0 1.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 GAP88623.1 - 0.0013 18.3 0.0 0.0044 16.6 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 GAP88623.1 - 0.081 12.8 0.0 0.081 12.8 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family GEMIN8 PF15348.6 GAP88623.1 - 0.85 9.9 12.3 0.11 12.8 6.5 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Pho88 PF10032.9 GAP88624.1 - 7.8e-80 266.4 0.0 8.8e-80 266.2 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) CAP_N PF01213.19 GAP88625.1 - 0.3 10.5 0.3 0.51 9.8 0.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal p450 PF00067.22 GAP88626.1 - 6.6e-69 232.8 0.0 9.6e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 GAP88626.1 - 1e-26 93.9 0.0 1.7e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAP88626.1 - 6.9e-25 87.9 0.1 2.3e-24 86.2 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 GAP88626.1 - 1.3e-08 35.5 0.0 3.2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 GAP88626.1 - 0.021 15.0 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Abhydrolase_1 PF00561.20 GAP88627.1 - 1.1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP88627.1 - 4.6e-07 29.4 0.1 6.9e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 GAP88627.1 - 0.00064 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 GAP88627.1 - 0.0018 17.1 0.0 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family EthD PF07110.11 GAP88627.1 - 0.068 14.3 3.4 0.24 12.6 0.1 3.1 4 0 0 4 4 4 0 EthD domain DUF1479 PF07350.12 GAP88629.1 - 1.1e-151 505.4 0.0 1.4e-151 505.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Cuticle_2 PF08184.11 GAP88630.1 - 0.024 14.6 0.1 0.052 13.6 0.1 1.5 1 0 0 1 1 1 0 Cuticle protein 7 isoform family Peptidase_M35 PF02102.15 GAP88632.1 - 1.9e-77 260.6 14.6 2.3e-77 260.3 14.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 GAP88632.1 - 4.6e-42 144.0 2.5 4.6e-42 144.0 2.5 1.6 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase NADH_oxidored PF08040.11 GAP88632.1 - 0.1 12.3 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 MNLL subunit p450 PF00067.22 GAP88633.1 - 1.5e-06 27.2 0.0 1.6e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAP88634.1 - 4.8e-57 193.7 0.0 5.7e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Paf1 PF03985.13 GAP88634.1 - 0.11 11.5 13.0 0.15 11.1 13.0 1.1 1 0 0 1 1 1 0 Paf1 RPN2_C PF18004.1 GAP88634.1 - 0.39 10.6 9.4 0.61 10.0 9.4 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FAM176 PF14851.6 GAP88634.1 - 0.56 9.9 6.2 0.92 9.2 6.2 1.3 1 0 0 1 1 1 0 FAM176 family Cytomega_UL84 PF06284.11 GAP88634.1 - 0.69 8.3 2.1 0.82 8.1 2.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Vfa1 PF08432.10 GAP88634.1 - 0.79 10.0 7.2 1.1 9.5 7.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Eapp_C PF10238.9 GAP88634.1 - 1.1 9.4 3.2 1.6 8.8 3.2 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Pap_E4 PF02711.14 GAP88634.1 - 1.5 9.8 3.1 48 5.0 0.0 2.3 2 0 0 2 2 2 0 E4 protein RR_TM4-6 PF06459.12 GAP88634.1 - 1.7 8.4 7.6 2.5 7.9 7.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 GAP88634.1 - 1.8 8.6 13.3 3.1 7.8 12.8 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Connexin PF00029.19 GAP88634.1 - 2.3 7.9 3.9 3.4 7.3 3.9 1.2 1 0 0 1 1 1 0 Connexin Pox_Ag35 PF03286.14 GAP88634.1 - 3 7.6 8.4 4.4 7.0 8.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.13 GAP88634.1 - 4.8 5.9 4.8 6.3 5.5 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4820 PF16091.5 GAP88634.1 - 5.8 6.2 6.2 8.2 5.7 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NARP1 PF12569.8 GAP88634.1 - 9.2 5.0 8.7 12 4.6 8.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CorA PF01544.18 GAP88635.1 - 1.6e-05 24.4 0.5 7.1e-05 22.3 0.5 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4153 PF13687.6 GAP88635.1 - 0.081 12.5 0.3 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4153) Syndecan PF01034.20 GAP88636.1 - 0.008 16.1 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.6 GAP88636.1 - 0.014 16.2 0.3 0.038 14.9 0.3 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2561 PF10812.8 GAP88636.1 - 0.023 14.7 0.8 0.048 13.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Phage_holin_3_6 PF07332.11 GAP88636.1 - 0.031 14.3 0.3 0.067 13.2 0.3 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DAP10 PF07213.11 GAP88636.1 - 0.04 13.9 0.7 0.083 12.9 0.7 1.4 1 0 0 1 1 1 0 DAP10 membrane protein RIFIN PF02009.16 GAP88636.1 - 0.047 13.6 0.5 0.078 12.9 0.3 1.4 1 1 0 1 1 1 0 Rifin DUF2681 PF10883.8 GAP88636.1 - 0.093 13.1 0.4 0.21 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Cadherin_C_2 PF16492.5 GAP88636.1 - 0.098 13.4 0.5 0.89 10.4 0.5 2.5 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Insulin_TMD PF17870.1 GAP88636.1 - 0.11 12.6 1.8 0.21 11.7 1.8 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment MAP17 PF15807.5 GAP88636.1 - 0.14 12.4 1.6 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Mycobact_memb PF05423.13 GAP88636.1 - 0.27 11.2 1.5 0.33 10.9 0.2 1.7 2 0 0 2 2 2 0 Mycobacterium membrane protein DUF4834 PF16118.5 GAP88636.1 - 1.5 9.9 3.8 0.87 10.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Adeno_E3_CR2 PF02439.15 GAP88636.1 - 4.4 7.1 7.5 0.67 9.8 3.5 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 FeoB_associated PF12669.7 GAP88636.1 - 6 7.4 6.1 15 6.1 6.1 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Fungal_trans PF04082.18 GAP88637.1 - 5.8e-22 78.0 0.0 4.8e-21 75.0 0.0 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP88637.1 - 5.3e-08 32.8 8.4 8.8e-08 32.2 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-PHD-like PF15446.6 GAP88637.1 - 0.023 14.3 1.6 0.053 13.1 1.6 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Peptidase_M41 PF01434.18 GAP88638.1 - 2.8e-56 190.4 1.4 5e-56 189.6 1.4 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 GAP88638.1 - 1e-42 145.7 0.0 2.5e-42 144.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAP88638.1 - 1.8e-10 40.5 0.1 5.9e-10 38.8 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 GAP88638.1 - 1.3e-05 25.2 0.0 4e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP88638.1 - 3.2e-05 24.2 0.0 0.033 14.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 GAP88638.1 - 3.8e-05 23.1 0.0 7.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 GAP88638.1 - 0.00012 22.5 1.1 0.0018 18.7 0.3 2.9 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAP88638.1 - 0.00056 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAP88638.1 - 0.0052 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 GAP88638.1 - 0.006 16.3 0.1 0.027 14.2 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 GAP88638.1 - 0.0066 16.0 0.9 0.58 9.7 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 GAP88638.1 - 0.0075 16.4 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAP88638.1 - 0.021 14.2 0.3 0.047 13.1 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 GAP88638.1 - 0.038 13.3 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 GAP88638.1 - 0.057 14.0 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAP88638.1 - 0.08 13.2 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 GAP88638.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 GAP88638.1 - 0.13 12.6 0.2 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 GAP88638.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAP88638.1 - 0.18 11.3 0.1 0.7 9.4 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Peptidase_M50B PF13398.6 GAP88638.1 - 0.43 10.2 0.0 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 Peptidase M50B-like GDPD PF03009.17 GAP88639.1 - 1.2e-69 235.0 0.0 2.5e-69 233.9 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 GAP88639.1 - 7.1e-25 87.4 0.1 2.9e-09 37.4 0.0 4.4 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88639.1 - 6e-23 80.9 3.1 7.4e-09 36.0 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeats (many copies) SPX PF03105.19 GAP88639.1 - 3.9e-18 66.6 9.1 4.3e-09 36.8 0.0 3.8 2 1 2 4 4 4 3 SPX domain Ank_5 PF13857.6 GAP88639.1 - 1.2e-15 57.3 0.8 4.4e-08 33.2 0.1 5.4 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88639.1 - 1.1e-13 50.0 4.5 0.0036 17.7 0.0 7.0 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 GAP88639.1 - 2.8e-11 43.3 8.8 0.00089 19.6 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat DUF1978 PF09321.10 GAP88639.1 - 0.039 13.3 0.1 0.079 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) SRA1 PF07304.11 GAP88639.1 - 0.14 11.9 0.0 1.2 9.0 0.0 2.4 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) Tnp_22_trimer PF17489.2 GAP88640.1 - 0.026 14.5 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 L1 transposable element trimerization domain PPR_1 PF12854.7 GAP88640.1 - 0.027 14.2 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 PPR repeat PPR_2 PF13041.6 GAP88640.1 - 0.1 12.8 0.1 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 PPR repeat family DUF866 PF05907.13 GAP88641.1 - 1.5e-64 216.6 0.4 1.6e-64 216.5 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_Tnp_IS1595 PF12760.7 GAP88641.1 - 0.018 15.0 1.5 0.038 14.0 1.5 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain HalOD2 PF18547.1 GAP88641.1 - 0.12 12.3 1.7 3.6 7.6 0.5 2.3 2 0 0 2 2 2 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 GAP88641.1 - 4.3 7.3 6.8 46 4.0 6.8 2.2 1 1 0 1 1 1 0 SprT-like zinc ribbon domain LSM PF01423.22 GAP88642.1 - 1.1e-18 66.7 0.2 1.2e-18 66.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF2888 PF11135.8 GAP88642.1 - 0.032 14.2 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) PRMT5_C PF17286.2 GAP88643.1 - 4.9e-57 192.7 0.0 5.6e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 GAP88644.1 - 5.6e-71 238.7 0.0 7.2e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 GAP88644.1 - 1.9e-60 203.6 0.0 3.4e-60 202.8 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 GAP88644.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Prefoldin_2 PF01920.20 GAP88645.1 - 3.3e-25 88.1 4.2 4.3e-25 87.7 4.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit PI3K_P85_iSH2 PF16454.5 GAP88645.1 - 0.0051 16.4 4.5 0.0097 15.5 4.5 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AKNA PF12443.8 GAP88645.1 - 0.05 14.3 1.2 0.061 14.0 0.1 1.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor APG6_N PF17675.1 GAP88645.1 - 0.29 11.6 11.7 8 7.0 7.8 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region FAM167 PF11652.8 GAP88645.1 - 6.1 7.4 8.2 7.5 7.1 1.8 3.1 1 1 1 3 3 3 0 FAM167 DivIC PF04977.15 GAP88645.1 - 9.6 6.1 10.3 5.9 6.7 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF2183 PF09949.9 GAP88646.1 - 3.6e-23 81.8 0.1 6.4e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) OB_NTP_bind PF07717.16 GAP88648.1 - 1.3e-20 73.6 0.0 3.9e-20 72.0 0.0 1.8 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 GAP88648.1 - 3.1e-18 66.0 0.0 8.2e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAP88648.1 - 4.5e-10 39.8 0.0 1.2e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAP88648.1 - 1.5e-08 34.6 0.1 2.9e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAP88648.1 - 1.3e-05 25.5 0.1 4.5e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 GAP88648.1 - 0.00018 21.2 0.1 0.00054 19.7 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 GAP88648.1 - 0.00057 19.7 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Pox_I1 PF03289.13 GAP88648.1 - 0.002 17.3 0.1 0.0036 16.5 0.1 1.3 1 0 0 1 1 1 1 Poxvirus protein I1 T2SSE PF00437.20 GAP88648.1 - 0.008 15.3 0.1 0.017 14.2 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 GAP88648.1 - 0.0085 16.1 0.2 0.02 14.9 0.2 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.9 GAP88648.1 - 0.05 12.8 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 GAP88648.1 - 0.068 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAP88648.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region JmjC PF02373.22 GAP88649.1 - 6.2e-37 126.5 0.5 2.2e-36 124.7 0.4 2.1 2 0 0 2 2 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 GAP88649.1 - 5e-19 68.5 5.1 9.1e-19 67.6 5.1 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 GAP88649.1 - 1.8e-17 63.4 5.4 1.8e-17 63.4 5.4 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 GAP88649.1 - 2.7e-14 52.8 1.6 5.6e-14 51.8 1.6 1.6 1 0 0 1 1 1 1 jmjN domain CENP-B_dimeris PF09026.10 GAP88649.1 - 0.017 15.5 7.2 0.056 13.8 7.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 GAP88649.1 - 0.018 13.4 0.8 0.027 12.8 0.8 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GAP88649.1 - 0.021 15.0 2.5 0.073 13.2 2.5 1.9 1 0 0 1 1 1 0 YL1 nuclear protein DUF3322 PF11795.8 GAP88649.1 - 0.025 14.6 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Importin_rep_6 PF18829.1 GAP88649.1 - 0.27 11.4 1.8 0.55 10.4 1.8 1.4 1 0 0 1 1 1 0 Importin repeat 6 PGA2 PF07543.12 GAP88649.1 - 1.7 8.6 5.4 5.4 7.0 5.4 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 DNA_pol_phi PF04931.13 GAP88649.1 - 4.3 5.3 6.4 7.2 4.6 6.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 GAP88653.1 - 6.2e-36 124.0 30.7 1.1e-35 123.3 30.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP88653.1 - 9.2e-10 38.0 16.5 1.2e-09 37.5 16.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF5090 PF17009.5 GAP88653.1 - 2.2 8.2 5.2 4.2 7.3 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DUF2070 PF09843.9 GAP88653.1 - 4.5 5.5 9.9 7.1 4.8 9.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) 2OG-FeII_Oxy_3 PF13640.6 GAP88654.1 - 1.7e-11 44.9 0.1 4.4e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 GAP88654.1 - 1.6e-05 25.3 0.0 3.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.6 GAP88655.1 - 6e-20 71.9 0.0 6.7e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 GAP88655.1 - 3.1e-14 52.8 0.0 7.5e-12 45.2 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Rep_fac_C PF08542.11 GAP88656.1 - 1.3e-17 64.0 0.0 3.6e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 GAP88656.1 - 3.8e-16 59.7 0.0 7e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 GAP88656.1 - 1.9e-12 47.2 0.0 1.1e-11 44.7 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 GAP88656.1 - 2.9e-08 33.9 0.0 6.3e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 GAP88656.1 - 3.7e-07 30.4 0.3 1e-06 29.0 0.0 1.8 2 0 0 2 2 1 1 AAA C-terminal domain AAA_30 PF13604.6 GAP88656.1 - 6.6e-07 29.2 0.3 1.5e-06 28.1 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAP88656.1 - 1.7e-06 28.5 0.0 5e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP88656.1 - 5.9e-06 26.6 0.0 1.6e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAP88656.1 - 8.6e-06 25.8 0.1 2.8e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 GAP88656.1 - 1.6e-05 24.2 0.0 2.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 GAP88656.1 - 1.7e-05 24.8 0.1 0.00013 21.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 GAP88656.1 - 3.9e-05 23.5 0.1 6.9e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 GAP88656.1 - 0.0001 22.2 0.1 0.00034 20.5 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAP88656.1 - 0.00019 21.2 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAP88656.1 - 0.00023 20.9 0.0 0.00079 19.2 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 GAP88656.1 - 0.00037 20.0 0.4 0.3 10.5 0.0 2.5 1 1 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.6 GAP88656.1 - 0.00058 20.2 0.2 0.0017 18.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAP88656.1 - 0.00058 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain TniB PF05621.11 GAP88656.1 - 0.00076 18.9 0.1 0.0049 16.3 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 GAP88656.1 - 0.001 19.1 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 GAP88656.1 - 0.0017 18.4 0.0 0.048 13.7 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.6 GAP88656.1 - 0.0032 17.7 0.0 0.0065 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAP88656.1 - 0.0089 16.6 0.0 0.022 15.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 GAP88656.1 - 0.012 15.2 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAP88656.1 - 0.012 15.0 0.1 0.059 12.8 0.1 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 GAP88656.1 - 0.021 14.6 0.1 0.22 11.2 0.1 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_25 PF13481.6 GAP88656.1 - 0.031 13.8 0.0 0.088 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAP88656.1 - 0.036 13.3 0.0 0.075 12.3 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 GAP88656.1 - 0.064 13.6 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 GAP88656.1 - 0.066 12.9 0.0 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein GCS2 PF04107.13 GAP88656.1 - 0.078 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) FtsK_SpoIIIE PF01580.18 GAP88656.1 - 0.081 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 GAP88656.1 - 0.081 12.8 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea StbA PF06406.11 GAP88656.1 - 0.17 11.1 1.9 4.7 6.3 0.1 2.2 2 0 0 2 2 2 0 StbA protein VTC PF09359.10 GAP88656.1 - 0.2 11.0 0.1 0.26 10.6 0.1 1.3 1 1 0 1 1 1 0 VTC domain Histone PF00125.24 GAP88658.1 - 7.3e-19 68.4 0.0 9.8e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 GAP88658.1 - 8.2e-13 47.9 0.1 2.1e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 GAP88658.1 - 2.7e-05 24.4 0.0 4.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.22 GAP88659.1 - 1.2e-09 38.0 0.1 2.6e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 GAP88659.1 - 0.00053 19.8 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3176 PF11374.8 GAP88660.1 - 2.7e-32 111.2 0.0 1.2e-31 109.1 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) adh_short PF00106.25 GAP88661.1 - 9.4e-07 28.5 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88661.1 - 1.4e-06 28.1 0.1 2.2e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88661.1 - 0.00018 21.5 0.8 0.00031 20.7 0.8 1.3 1 0 0 1 1 1 1 KR domain PALP PF00291.25 GAP88661.1 - 0.0064 15.9 1.8 0.0087 15.5 1.8 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Striatin PF08232.12 GAP88663.1 - 9e-41 140.1 1.1 9e-41 140.1 1.1 1.8 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 GAP88663.1 - 3.6e-24 84.6 14.9 0.00061 20.5 0.1 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP88663.1 - 8.2e-05 22.8 0.1 1 9.7 0.0 4.5 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain CALCOCO1 PF07888.11 GAP88663.1 - 0.0032 16.4 1.4 0.0052 15.7 1.4 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like eIF2A PF08662.11 GAP88663.1 - 0.078 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAP88663.1 - 0.083 11.8 0.0 0.96 8.3 0.0 2.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAP88663.1 - 0.21 10.0 0.0 0.41 9.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain 4HBT PF03061.22 GAP88664.1 - 3.5e-12 46.5 0.1 5e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4129 PF13559.6 GAP88665.1 - 2e-06 28.0 0.0 2e-06 28.0 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 GAP88665.1 - 0.006 16.6 7.9 0.14 12.2 0.0 2.9 3 0 0 3 3 3 2 NICE-3 protein WSS_VP PF12175.8 GAP88665.1 - 0.54 9.7 2.2 0.9 9.0 2.2 1.3 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP DUF3923 PF13061.6 GAP88665.1 - 0.87 9.7 9.8 1.5 9.0 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3923) Ndc1_Nup PF09531.10 GAP88666.1 - 6.8e-170 566.7 0.1 7.7e-170 566.6 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 GAP88667.1 - 6.1e-23 81.1 1.2 6.1e-23 81.1 1.2 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 GAP88667.1 - 1.3e-14 53.9 0.6 3e-14 52.8 0.6 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 GAP88667.1 - 0.00013 21.7 10.6 0.00047 19.9 10.6 2.0 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 GAP88667.1 - 0.014 15.2 0.3 0.16 11.8 0.2 2.4 2 0 0 2 2 2 0 Synaptobrevin CEP209_CC5 PF16574.5 GAP88667.1 - 0.24 11.5 11.5 3.3 7.9 0.3 2.5 2 1 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 Spectrin PF00435.21 GAP88667.1 - 0.52 10.8 12.9 1.3 9.5 11.2 2.3 1 1 1 2 2 2 0 Spectrin repeat DUF1664 PF07889.12 GAP88667.1 - 0.53 10.3 7.3 0.64 10.1 2.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 GAP88667.1 - 3.5 5.4 9.2 6.9 4.5 4.3 2.4 1 1 2 3 3 3 0 Prominin APG6_N PF17675.1 GAP88667.1 - 5.9 7.4 15.9 0.55 10.7 8.6 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF16 PF01519.16 GAP88667.1 - 6.9 7.2 13.2 0.45 11.0 1.9 3.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 60KD_IMP PF02096.20 GAP88668.1 - 0.0026 17.7 0.0 0.0033 17.4 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF4395 PF14340.6 GAP88669.1 - 0.088 13.1 1.5 0.3 11.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) AIM5 PF17050.5 GAP88669.1 - 0.13 13.0 2.3 0.18 12.6 0.8 1.9 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 ALG11_N PF15924.5 GAP88670.1 - 1.2e-81 273.7 0.1 3e-81 272.5 0.0 1.6 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 GAP88670.1 - 2.8e-19 69.3 0.0 4.2e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAP88670.1 - 1.6e-09 38.3 0.0 3.1e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAP88670.1 - 0.00031 20.8 0.2 0.00081 19.4 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 G_glu_transpept PF01019.21 GAP88671.1 - 7.1e-160 533.1 1.6 9.1e-160 532.8 1.6 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase tRNA_U5-meth_tr PF05958.11 GAP88672.1 - 2.2e-08 33.5 0.0 0.00085 18.4 0.0 3.3 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 GAP88672.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 GAP88672.1 - 0.021 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 GAP88672.1 - 0.022 15.4 0.0 0.057 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UNC45-central PF11701.8 GAP88673.1 - 4.6e-49 166.3 0.5 1.3e-47 161.6 0.0 3.3 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central LptF_LptG PF03739.14 GAP88673.1 - 0.11 11.3 0.4 0.2 10.5 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG TetR_C_28 PF17937.1 GAP88673.1 - 2.8 8.5 6.8 1.3 9.5 0.0 3.9 5 0 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain Arm PF00514.23 GAP88673.1 - 3.3 7.9 13.4 36 4.6 0.3 6.6 6 1 0 7 7 7 0 Armadillo/beta-catenin-like repeat Tfb4 PF03850.14 GAP88674.1 - 1.1e-87 294.1 0.0 1.2e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Asparaginase_2 PF01112.18 GAP88675.1 - 1.6e-45 155.5 6.0 4.8e-30 104.6 0.1 2.2 2 0 0 2 2 2 2 Asparaginase NRIP1_repr_1 PF15687.5 GAP88675.1 - 2.2 7.9 8.3 5.7 6.5 1.3 2.4 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 1 Actin PF00022.19 GAP88676.1 - 1.3e-86 290.8 0.0 8.9e-53 179.4 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 GAP88676.1 - 0.11 11.3 0.0 4 6.2 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Fungal_trans_2 PF11951.8 GAP88677.1 - 2.7e-09 36.3 0.4 3.9e-09 35.8 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP88677.1 - 1.1e-07 31.8 10.0 2.7e-07 30.6 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAP88678.1 - 6.8e-54 183.1 34.2 6.8e-54 183.1 34.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP88678.1 - 2.2e-13 49.9 12.1 2.2e-13 49.9 12.1 3.3 2 1 2 4 4 4 1 Sugar (and other) transporter MFS_4 PF06779.14 GAP88678.1 - 5.4e-07 29.2 6.5 5.4e-07 29.2 6.5 3.4 2 1 2 4 4 4 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 GAP88678.1 - 0.00053 18.5 3.1 0.00073 18.1 3.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector p450 PF00067.22 GAP88679.1 - 3.9e-67 227.0 0.0 4.5e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FlbD PF06289.11 GAP88679.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins HNH_2 PF13391.6 GAP88680.1 - 1.5e-07 31.5 0.5 3.9e-07 30.1 0.5 1.7 1 0 0 1 1 1 1 HNH endonuclease FAD_binding_4 PF01565.23 GAP88681.1 - 6.3e-21 74.6 1.5 6.3e-21 74.6 1.5 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAP88681.1 - 8.4e-12 45.0 1.5 1.2e-11 44.5 0.3 1.9 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 GAP88681.1 - 0.082 12.3 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ketoacyl-synt PF00109.26 GAP88682.1 - 5.2e-63 213.0 0.1 1.6e-61 208.1 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP88682.1 - 8.7e-56 188.7 0.0 2e-55 187.5 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 GAP88682.1 - 4.4e-41 141.4 0.1 1.3e-40 139.9 0.1 1.7 1 1 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAP88682.1 - 1.3e-40 139.5 0.0 3.6e-40 138.1 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAP88682.1 - 1.6e-35 121.7 0.0 4.5e-35 120.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAP88682.1 - 1.7e-14 54.4 0.0 4.7e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAP88682.1 - 3.7e-13 49.9 0.0 8.8e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAP88682.1 - 1.8e-09 37.4 0.0 3.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 GAP88682.1 - 6.8e-09 36.3 0.1 2.3e-08 34.6 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP88682.1 - 6.1e-08 32.6 0.0 1.8e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP88682.1 - 2.4e-07 31.3 0.0 6.5e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP88682.1 - 1e-06 28.7 0.0 2.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 GAP88682.1 - 0.00021 21.6 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 GAP88682.1 - 0.0012 18.3 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 GAP88682.1 - 0.0013 18.2 1.2 0.0094 15.3 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain SAT PF16073.5 GAP88682.1 - 0.0067 16.2 0.5 0.025 14.3 0.5 1.8 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FSH1 PF03959.13 GAP88683.1 - 3.1e-32 112.0 0.0 3.8e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 GAP88683.1 - 4e-05 24.3 0.5 9.2e-05 23.1 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LEM PF03020.15 GAP88683.1 - 0.096 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 LEM domain adh_short_C2 PF13561.6 GAP88684.1 - 1.3e-48 165.6 0.5 5.3e-48 163.6 0.5 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP88684.1 - 1.4e-38 132.3 2.1 4.2e-38 130.8 2.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP88684.1 - 9e-09 35.5 1.1 9.6e-09 35.4 0.0 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAP88684.1 - 0.004 16.3 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.15 GAP88684.1 - 0.0043 16.9 0.2 0.28 11.0 0.0 2.1 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Ldh_1_N PF00056.23 GAP88684.1 - 0.018 15.2 0.4 0.035 14.2 0.4 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.21 GAP88684.1 - 0.021 14.2 1.5 0.044 13.1 1.5 1.5 1 0 0 1 1 1 0 ThiF family Epimerase PF01370.21 GAP88684.1 - 0.048 13.1 0.2 0.7 9.3 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 GAP88686.1 - 6.5e-29 101.0 44.1 1.2e-28 100.1 44.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP88686.1 - 1.5e-07 30.7 6.5 1.5e-07 30.7 6.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Pox_Ag35 PF03286.14 GAP88686.1 - 1.7 8.4 3.3 2.5 7.9 3.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CMD PF02627.20 GAP88687.1 - 0.00059 19.8 0.0 0.0012 18.8 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family FAD_binding_3 PF01494.19 GAP88688.1 - 2.7e-13 49.9 0.5 0.00031 20.1 0.4 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.27 GAP88688.1 - 3.5e-05 24.3 0.2 6.6e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP88688.1 - 4.4e-05 22.7 0.0 6.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAP88688.1 - 0.00019 20.3 0.8 0.00027 19.8 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAP88688.1 - 0.00092 18.5 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP88688.1 - 0.001 19.3 0.1 0.0034 17.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 GAP88688.1 - 0.0058 15.9 0.7 0.011 15.1 0.7 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAP88688.1 - 0.014 14.8 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 GAP88688.1 - 0.048 13.2 0.1 0.45 10.1 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 GAP88688.1 - 0.3 10.1 0.4 0.43 9.6 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A GMC_oxred_N PF00732.19 GAP88689.1 - 5e-63 213.2 0.0 8.7e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP88689.1 - 3.9e-31 108.5 0.0 6.7e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAP88689.1 - 4.6e-06 25.9 0.7 7.2e-06 25.3 0.7 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 GAP88689.1 - 0.001 18.3 0.2 0.014 14.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 GAP88689.1 - 0.019 14.0 1.0 1.7 7.7 0.6 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 GAP88689.1 - 0.042 13.4 0.7 0.3 10.6 0.6 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 GAP88689.1 - 0.077 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Peptidase_S8 PF00082.22 GAP88690.1 - 2.7e-12 46.6 0.1 1.1e-11 44.5 0.1 2.0 1 1 0 1 1 1 1 Subtilase family Pkinase PF00069.25 GAP88691.1 - 5.4e-27 94.8 0.0 9.5e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP88691.1 - 6.8e-17 61.6 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.11 GAP88691.1 - 6.7e-13 49.2 0.0 1.4e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_fungal PF17667.1 GAP88691.1 - 0.00068 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PolyG_pol PF01518.16 GAP88691.1 - 0.08 11.6 0.1 0.47 9.1 0.0 2.0 2 0 0 2 2 2 0 Sigma NS protein TPR_12 PF13424.6 GAP88695.1 - 4.3e-20 71.8 0.7 3.1e-09 37.0 0.2 4.9 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAP88695.1 - 4.2e-15 55.1 8.5 2.3e-07 30.4 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.22 GAP88695.1 - 4.1e-09 36.0 0.0 8.8e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_MalT PF17874.1 GAP88695.1 - 4.4e-08 32.9 2.4 8e-08 32.0 0.1 2.4 3 0 0 3 3 3 1 MalT-like TPR region TPR_1 PF00515.28 GAP88695.1 - 5.1e-06 26.1 0.6 0.19 11.6 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAP88695.1 - 5.2e-06 26.1 0.0 0.38 10.9 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 GAP88695.1 - 8.1e-05 23.3 1.2 0.0002 22.1 0.3 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family TPR_2 PF07719.17 GAP88695.1 - 0.0006 19.7 3.1 0.55 10.5 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 GAP88695.1 - 0.0011 18.9 0.1 0.32 11.0 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 GAP88695.1 - 0.0014 19.0 3.0 0.21 12.3 0.0 4.2 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAP88695.1 - 0.0018 18.8 0.5 3.8 8.1 0.1 4.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAP88695.1 - 0.0032 17.6 0.5 4.2 7.8 0.1 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat PGAP1 PF07819.13 GAP88695.1 - 0.0051 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein TPR_14 PF13428.6 GAP88695.1 - 0.0056 17.4 7.5 26 6.0 0.2 6.4 6 1 1 7 7 6 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 GAP88695.1 - 0.007 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AAA_5 PF07728.14 GAP88695.1 - 0.021 14.8 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAP88695.1 - 0.029 14.7 0.0 0.19 12.1 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain TPR_16 PF13432.6 GAP88695.1 - 0.054 14.2 0.6 31 5.3 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat AAA_24 PF13479.6 GAP88695.1 - 0.069 12.9 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 GAP88695.1 - 0.13 12.6 0.0 0.77 10.0 0.0 2.3 2 0 0 2 2 1 0 AAA domain DUF676 PF05057.14 GAP88695.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) CHAT PF12770.7 GAP88696.1 - 2.2e-06 27.3 0.0 3.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 CHAT domain TMEM144 PF07857.12 GAP88696.1 - 0.38 9.7 1.7 0.66 8.9 1.7 1.3 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters PLA2_B PF01735.18 GAP88698.1 - 1.6e-193 643.6 0.0 1.9e-193 643.4 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain SopA PF13981.6 GAP88698.1 - 0.19 12.2 0.0 0.7 10.3 0.0 1.8 2 0 0 2 2 2 0 SopA-like central domain Nop14 PF04147.12 GAP88700.1 - 5 5.2 5.3 7.1 4.7 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family Asp PF00026.23 GAP88701.1 - 1.5e-71 241.4 0.1 1.8e-71 241.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP88701.1 - 1.7e-10 41.4 0.4 1.1e-05 25.7 0.0 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAP88701.1 - 6.1e-06 26.8 0.8 0.013 16.1 0.4 3.1 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAP88701.1 - 0.0056 17.2 0.2 1.4 9.5 0.1 3.0 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease Cation_efflux PF01545.21 GAP88702.1 - 2.8e-48 164.3 17.2 1.7e-47 161.7 17.2 1.9 1 1 0 1 1 1 1 Cation efflux family Glyoxalase PF00903.25 GAP88703.1 - 1.5e-15 57.5 0.0 2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GAP88703.1 - 1.5e-05 25.7 0.1 3.2e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 Glyoxalase-like domain Glyco_hydro_3_C PF01915.22 GAP88704.1 - 1.6e-60 204.6 0.0 3.2e-60 203.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAP88704.1 - 2.6e-56 191.3 0.0 4.5e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAP88704.1 - 2.1e-23 82.2 0.1 4.6e-23 81.1 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 GAP88704.1 - 1.1e-22 80.4 0.0 1.7e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 PA14 domain TetR_C_7 PF14246.6 GAP88704.1 - 0.09 12.8 0.1 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Metallophos PF00149.28 GAP88705.1 - 3.2e-10 40.8 3.8 6.4e-10 39.9 3.8 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.24 GAP88706.1 - 1e-119 400.4 22.1 1.2e-119 400.2 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP88706.1 - 4.8e-19 68.5 41.0 7.7e-13 48.1 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_2 PF00890.24 GAP88707.1 - 1.6e-84 284.4 1.4 2.3e-84 283.9 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 GAP88707.1 - 5.6e-22 77.7 0.1 7.5e-21 74.1 0.0 2.9 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 GAP88707.1 - 7.4e-15 55.4 0.5 1.6e-14 54.3 0.5 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAP88707.1 - 1.7e-09 37.5 1.1 6.9e-09 35.6 1.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP88707.1 - 8.4e-08 32.3 2.3 5.3e-07 29.8 0.4 2.9 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP88707.1 - 2.4e-07 30.3 1.1 5.7e-06 25.8 0.8 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP88707.1 - 5.1e-06 25.4 3.0 0.0067 15.2 0.1 3.5 3 1 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 GAP88707.1 - 5.3e-06 25.9 0.0 0.054 12.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP88707.1 - 9.8e-05 21.7 0.5 0.024 13.9 0.2 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 GAP88707.1 - 0.0011 18.1 2.2 0.082 12.0 0.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 GAP88707.1 - 0.003 16.9 5.1 0.023 14.0 5.1 2.1 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 GAP88707.1 - 0.014 14.8 1.3 0.3 10.3 0.2 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 GAP88707.1 - 0.025 15.1 3.0 2.2 8.9 0.7 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAP88707.1 - 0.026 13.8 0.5 0.052 12.8 0.5 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fasciclin PF02469.22 GAP88708.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 Fasciclin domain Sin3a_C PF16879.5 GAP88709.1 - 9.9e-74 248.6 6.5 1.9e-73 247.7 5.0 2.3 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 GAP88709.1 - 1.8e-45 152.8 9.6 8.8e-18 64.2 2.0 4.2 4 1 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 GAP88709.1 - 7.1e-38 128.6 0.0 3.3e-37 126.5 0.0 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor Pollen_allerg_1 PF01357.21 GAP88709.1 - 0.13 12.3 0.3 0.52 10.4 0.3 2.0 2 0 0 2 2 2 0 Pollen allergen Thiolase_N PF00108.23 GAP88710.1 - 1.7e-93 312.7 2.4 1.8e-93 312.7 1.5 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAP88710.1 - 1.8e-45 153.5 0.7 4.1e-45 152.4 0.7 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAP88710.1 - 0.00078 19.1 0.6 0.00078 19.1 0.6 2.1 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 GAP88710.1 - 0.34 10.8 4.4 0.72 9.7 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.27 GAP88711.1 - 1.3e-46 158.6 0.0 2e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 GAP88711.1 - 7.5e-37 126.6 4.8 1.5e-36 125.7 4.8 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 GAP88711.1 - 2.2e-24 85.6 0.0 4.8e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 GAP88711.1 - 4.5e-18 65.1 0.0 1.2e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAP88711.1 - 1.5e-08 34.9 0.0 3.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAP88711.1 - 1.9e-06 27.8 0.0 4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAP88711.1 - 0.00024 21.1 0.1 0.00047 20.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeS_assembly_P PF01883.19 GAP88712.1 - 8.1e-09 35.5 0.4 3.9e-08 33.4 0.0 2.2 2 1 0 2 2 2 1 Iron-sulfur cluster assembly protein Fungal_trans PF04082.18 GAP88713.1 - 2.2e-12 46.6 0.1 3.7e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP88713.1 - 2.7e-07 30.6 9.0 6.6e-07 29.3 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Esterase_phd PF10503.9 GAP88714.1 - 3.9e-22 78.9 3.7 3.9e-22 78.9 3.7 1.6 1 1 1 2 2 2 1 Esterase PHB depolymerase CBM_1 PF00734.18 GAP88714.1 - 3.3e-13 49.3 8.0 3.3e-13 49.3 8.0 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 GAP88714.1 - 2.3e-11 43.6 0.9 3.6e-11 43.0 0.9 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAP88714.1 - 0.0035 18.0 1.8 0.0047 17.6 1.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAP88714.1 - 0.019 14.8 0.3 0.037 13.9 0.3 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 GAP88714.1 - 0.034 13.0 0.2 0.066 12.1 0.2 1.5 1 1 0 1 1 1 0 Carboxylesterase family Ank_2 PF12796.7 GAP88715.1 - 9.3e-23 80.6 0.0 3.3e-07 30.8 0.0 4.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP88715.1 - 1.8e-15 55.5 0.0 0.038 14.5 0.0 6.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GAP88715.1 - 9e-13 48.2 0.0 0.078 13.3 0.0 6.0 3 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAP88715.1 - 5.2e-12 45.6 0.0 0.12 12.9 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 GAP88715.1 - 9.8e-12 45.2 0.0 1.5e-05 25.5 0.0 5.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) p450 PF00067.22 GAP88716.1 - 1.5e-30 106.4 0.0 1.3e-20 73.7 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Methyltransf_25 PF13649.6 GAP88717.1 - 3.1e-08 34.2 0.0 8.1e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP88717.1 - 4.2e-08 33.2 0.0 5.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP88717.1 - 1.4e-06 29.0 0.0 3.9e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP88717.1 - 3.5e-05 24.4 0.0 7.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP88717.1 - 7.7e-05 22.5 0.0 0.00076 19.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP88717.1 - 0.0021 17.4 0.0 0.013 14.9 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 GAP88717.1 - 0.018 14.5 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Inhibitor_Mig-6 PF11555.8 GAP88717.1 - 0.1 12.7 0.6 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Abhydrolase_6 PF12697.7 GAP88718.1 - 6.6e-10 40.0 5.7 6.6e-10 40.0 5.7 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP88718.1 - 2.8e-09 36.6 0.3 5.7e-09 35.6 0.3 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP88718.1 - 9.9e-06 25.4 0.2 2.3e-05 24.2 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP88718.1 - 0.0052 16.3 0.3 0.47 9.9 0.1 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family GST_N_3 PF13417.6 GAP88720.1 - 2e-13 50.5 0.1 3.8e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP88720.1 - 2.2e-12 47.0 0.0 3.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAP88720.1 - 2.3e-11 43.8 0.1 4.1e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAP88720.1 - 4.6e-11 42.9 0.0 7.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAP88720.1 - 1.2e-09 38.3 0.0 2.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP88720.1 - 0.0015 18.5 0.2 0.0032 17.4 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.22 GAP88721.1 - 2.5e-41 141.9 0.1 3.1e-41 141.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ada_Zn_binding PF02805.16 GAP88721.1 - 0.15 12.1 0.2 0.47 10.5 0.1 1.8 2 0 0 2 2 2 0 Metal binding domain of Ada Prenyltrans PF00432.21 GAP88722.1 - 0.0017 18.1 0.2 5.3 6.9 0.0 4.1 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat MBOAT PF03062.19 GAP88723.1 - 1.5e-48 165.9 20.7 1.5e-48 165.9 20.7 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.11 GAP88723.1 - 0.0026 17.8 0.0 0.085 13.0 0.0 2.4 2 0 0 2 2 2 1 PufQ cytochrome subunit Far-17a_AIG1 PF04750.14 GAP88724.1 - 1.8e-06 27.4 10.7 2.6e-06 26.9 10.7 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF2613 PF11021.8 GAP88724.1 - 0.096 12.8 3.3 0.27 11.4 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF948 PF06103.11 GAP88725.1 - 0.055 13.7 0.8 1.2 9.5 0.1 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 GAP88725.1 - 0.091 12.8 1.2 0.43 10.6 0.6 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.21 GAP88725.1 - 0.16 11.8 2.1 7.2 6.4 0.5 2.6 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SPT6_acidic PF14632.6 GAP88726.1 - 0.029 14.9 3.7 0.029 14.9 3.7 3.0 2 1 1 3 3 3 0 Acidic N-terminal SPT6 F-box-like PF12937.7 GAP88727.1 - 2e-10 40.4 0.0 5.8e-10 38.9 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAP88727.1 - 0.0066 16.3 0.2 0.013 15.3 0.2 1.5 1 0 0 1 1 1 1 F-box domain Mito_carr PF00153.27 GAP88728.1 - 5.5e-64 212.1 2.7 3.8e-21 74.8 0.1 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein UDG PF03167.19 GAP88729.1 - 2.9e-20 72.8 0.0 4.8e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF1708 PF08101.11 GAP88730.1 - 1.4e-177 591.2 0.0 1.8e-177 590.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) SRF-TF PF00319.18 GAP88731.1 - 1.3e-22 79.0 0.3 1.9e-22 78.4 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.8 GAP88732.1 - 1.7e-168 560.9 0.2 2.9e-168 560.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 GAP88732.1 - 0.0041 16.9 0.6 0.011 15.6 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GAP88732.1 - 0.0047 16.9 0.7 0.0092 16.0 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle MerR-DNA-bind PF09278.11 GAP88732.1 - 0.032 14.8 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 MerR, DNA binding Exonuc_VIII PF06630.11 GAP88732.1 - 0.081 12.8 0.3 0.21 11.5 0.3 1.6 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII Sec61_beta PF03911.16 GAP88733.1 - 2.9e-19 68.8 1.9 3.9e-19 68.4 1.9 1.2 1 0 0 1 1 1 1 Sec61beta family DUF1180 PF06679.12 GAP88733.1 - 0.012 16.0 2.8 0.014 15.8 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NAPRTase PF04095.16 GAP88734.1 - 2.9e-59 200.6 0.1 5.7e-58 196.4 0.1 2.0 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 GAP88734.1 - 4.5e-33 114.3 0.0 7.9e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain APH PF01636.23 GAP88735.1 - 3.1e-19 69.8 0.0 1.1e-18 68.0 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP88735.1 - 0.003 17.2 0.0 0.0091 15.6 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 GAP88735.1 - 0.014 15.0 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Beta-lactamase PF00144.24 GAP88736.1 - 7.1e-54 183.3 0.0 1.2e-53 182.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase WD40 PF00400.32 GAP88736.1 - 8.3e-34 115.1 30.0 4.6e-09 36.8 0.1 12.5 15 0 0 15 15 14 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP88736.1 - 9.7e-16 57.9 0.4 0.38 11.1 0.0 7.3 5 3 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 GAP88736.1 - 4.1e-11 43.1 0.0 8.7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 GAP88736.1 - 6.9e-11 42.4 0.0 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ge1_WD40 PF16529.5 GAP88736.1 - 1.3e-09 37.5 0.1 0.09 11.7 0.0 5.4 4 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 GAP88736.1 - 1.5e-05 25.4 0.6 0.00094 19.6 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain PD40 PF07676.12 GAP88736.1 - 1.5e-05 24.8 2.5 0.29 11.1 0.0 5.2 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DUF3471 PF11954.8 GAP88736.1 - 2.3e-05 24.8 0.1 6.6e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) AAA PF00004.29 GAP88736.1 - 0.00029 21.3 0.0 0.001 19.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAP88736.1 - 0.0011 19.3 0.0 0.3 11.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 GAP88736.1 - 0.064 13.8 0.0 0.39 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 GAP88736.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nbas_N PF15492.6 GAP88736.1 - 0.097 12.0 0.5 7.7 5.7 0.0 3.6 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal MeaB PF03308.16 GAP88736.1 - 0.15 11.0 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 GAP88736.1 - 0.17 12.2 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 GAP88736.1 - 0.18 11.1 0.0 0.45 9.8 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family ZinT PF09223.11 GAP88737.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment Peptidase_S8 PF00082.22 GAP88738.1 - 1.1e-13 51.2 0.5 2.2e-13 50.2 0.2 1.6 2 0 0 2 2 2 1 Subtilase family Ank_2 PF12796.7 GAP88738.1 - 4.9e-09 36.6 0.3 5.6e-07 30.1 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88738.1 - 2.3e-08 34.4 0.8 0.18 12.4 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88738.1 - 6.4e-08 32.3 1.1 0.15 12.7 0.0 5.0 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 GAP88738.1 - 8.6e-08 32.3 1.7 0.11 13.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAP88738.1 - 0.014 15.7 0.4 8.8 6.8 0.1 4.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP88740.1 - 2.3e-06 28.1 0.2 0.16 12.6 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP88740.1 - 9.4e-05 22.6 0.3 1.2 9.5 0.0 4.0 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Peptidase_S8 PF00082.22 GAP88740.1 - 0.0018 17.6 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 Subtilase family RIG-I_C PF18119.1 GAP88740.1 - 0.083 12.9 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain Fungal_trans PF04082.18 GAP88741.1 - 7.7e-14 51.4 0.2 1.8e-13 50.1 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP88741.1 - 3.2e-07 30.3 11.1 5.8e-07 29.5 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.20 GAP88742.1 - 7.9e-54 183.3 1.1 1e-53 182.9 1.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2092 PF09865.9 GAP88742.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) YSIRK_signal PF04650.17 GAP88743.1 - 0.34 10.8 2.2 0.58 10.1 2.2 1.4 1 0 0 1 1 1 0 YSIRK type signal peptide Uma2 PF05685.12 GAP88744.1 - 0.049 13.2 0.0 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Putative restriction endonuclease Bac_rhodopsin PF01036.18 GAP88745.1 - 3.5e-57 193.5 12.6 4.7e-57 193.1 12.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1516 PF07457.11 GAP88745.1 - 0.11 12.6 2.9 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) MARVEL PF01284.23 GAP88745.1 - 0.14 12.1 0.3 0.14 12.1 0.3 3.1 3 0 0 3 3 3 0 Membrane-associating domain RPE65 PF03055.15 GAP88746.1 - 5.7e-74 250.0 0.0 7.2e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Pkinase PF00069.25 GAP88746.1 - 8.4e-43 146.6 0.0 2.8e-42 144.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP88746.1 - 7.4e-30 104.1 0.0 1.1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP88746.1 - 0.004 16.5 0.1 0.19 11.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Epimerase PF01370.21 GAP88747.1 - 1.1e-09 38.1 0.0 2.1e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 GAP88747.1 - 4.4e-05 23.0 0.2 0.00019 20.9 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 GAP88747.1 - 0.00024 20.6 0.0 0.0085 15.5 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAP88747.1 - 0.00064 18.9 0.0 0.0018 17.5 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 GAP88747.1 - 0.00065 19.3 0.0 0.0022 17.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 GAP88747.1 - 0.0088 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Rossmann-like PF10727.9 GAP88747.1 - 0.045 13.6 0.2 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain TFIIS_M PF07500.14 GAP88748.1 - 1.5e-26 93.1 2.0 1.9e-26 92.8 0.7 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 GAP88748.1 - 5.1e-17 61.4 7.0 1.1e-16 60.4 7.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 GAP88748.1 - 2.5e-10 40.2 0.4 8.7e-10 38.5 0.4 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PPDK_N PF01326.19 GAP88748.1 - 0.0079 15.5 0.3 0.017 14.4 0.1 1.7 2 0 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Cript PF10235.9 GAP88748.1 - 0.41 11.3 7.0 1.4 9.5 7.0 2.0 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT MAGE_N PF12440.8 GAP88748.1 - 6.7 7.5 14.7 2.4 8.9 3.9 2.6 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal PALP PF00291.25 GAP88749.1 - 3.2e-62 210.6 2.0 3.2e-62 210.6 2.0 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Alph_Pro_TM PF09608.10 GAP88749.1 - 0.096 12.5 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) MRC1 PF09444.10 GAP88749.1 - 0.12 12.8 0.2 0.35 11.4 0.2 1.7 1 0 0 1 1 1 0 MRC1-like domain Methyltransf_28 PF02636.17 GAP88750.1 - 1.9e-38 132.6 0.0 3.3e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 GAP88750.1 - 0.00051 19.9 0.0 0.0032 17.3 0.0 2.1 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase tRNA-synt_2c PF01411.19 GAP88751.1 - 4.9e-213 708.6 0.5 6.9e-213 708.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAP88751.1 - 6.1e-16 58.2 0.4 1.5e-15 57.0 0.4 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 GAP88751.1 - 1.4e-10 41.8 2.7 1.4e-10 41.8 2.7 1.9 2 0 0 2 2 2 1 DHHA1 domain Kelch_4 PF13418.6 GAP88751.1 - 0.25 11.4 0.5 3.4 7.7 0.0 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain Macoilin PF09726.9 GAP88752.1 - 6.5 5.2 9.7 8.2 4.9 9.7 1.2 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 GAP88752.1 - 8.3 5.5 6.0 9.2 5.4 6.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RCR PF12273.8 GAP88753.1 - 1.8e-10 41.5 10.6 3.1e-10 40.8 10.6 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4405 PF14358.6 GAP88754.1 - 0.46 11.1 9.2 2.5 8.7 0.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4405) p450 PF00067.22 GAP88755.1 - 8.5e-34 117.1 0.0 1e-31 110.2 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 GAP88756.1 - 3.2e-39 134.9 48.1 3.2e-39 134.9 48.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP88756.1 - 2.6e-14 52.6 12.0 2.6e-14 52.6 12.0 1.9 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Corona_S2 PF01601.16 GAP88756.1 - 0.51 8.8 4.3 0.8 8.1 4.3 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein p450 PF00067.22 GAP88757.1 - 3.9e-28 98.4 0.1 1.1e-25 90.4 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 GAP88758.1 - 2.4e-50 171.6 0.0 3.3e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sel1 PF08238.12 GAP88759.1 - 1.3e-37 127.3 37.8 9.5e-08 32.5 0.1 12.0 13 0 0 13 13 13 8 Sel1 repeat TPR_7 PF13176.6 GAP88759.1 - 0.062 13.4 8.0 0.55 10.4 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat SARAF PF06682.12 GAP88759.1 - 0.066 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TPR_8 PF13181.6 GAP88759.1 - 0.25 11.6 1.7 13 6.3 0.3 4.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAP88759.1 - 0.57 10.7 4.7 75 4.0 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 GAP88759.1 - 4.4 6.7 12.4 2.2 7.6 0.1 3.6 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 GAP88759.1 - 4.7 7.2 11.7 10 6.1 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.32 GAP88760.1 - 5.7e-06 27.0 4.4 0.19 12.6 0.1 4.5 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP88760.1 - 0.0056 16.9 0.1 0.96 9.8 0.0 3.1 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain FRG1 PF06229.12 GAP88761.1 - 6.3e-49 166.3 0.1 7.9e-49 166.0 0.1 1.1 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 GAP88761.1 - 0.032 14.5 0.0 0.25 11.5 0.0 2.1 2 1 0 2 2 2 0 Fascin domain DUF569 PF04601.13 GAP88761.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF569) 2OG-FeII_Oxy PF03171.20 GAP88762.1 - 0.0057 17.1 0.0 0.022 15.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF485 PF04341.12 GAP88763.1 - 0.65 10.0 4.0 0.27 11.2 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Thioredoxin_4 PF13462.6 GAP88764.1 - 1.7e-07 31.6 0.0 3.8e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 GAP88764.1 - 0.13 12.0 3.3 2.4 7.9 0.1 2.9 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Mur_ligase_M PF08245.12 GAP88765.1 - 0.026 14.5 0.0 0.23 11.5 0.0 2.3 1 1 0 1 1 1 0 Mur ligase middle domain Mur_ligase_C PF02875.21 GAP88765.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF3446 PF11928.8 GAP88766.1 - 0.18 12.1 8.5 1.4 9.3 0.1 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Mitofilin PF09731.9 GAP88767.1 - 1.1e-30 107.2 2.0 1.2e-30 107.0 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF4363 PF14276.6 GAP88767.1 - 0.047 13.8 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) Mitofilin PF09731.9 GAP88768.1 - 3.3e-67 227.8 20.3 6.1e-46 157.5 19.0 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein ALIX_LYPXL_bnd PF13949.6 GAP88768.1 - 0.0064 15.8 11.8 0.011 15.1 11.8 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV V-ATPase_G_2 PF16999.5 GAP88768.1 - 0.089 13.2 12.1 0.22 12.0 12.1 1.6 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF2096 PF09869.9 GAP88768.1 - 0.26 11.4 5.9 0.47 10.5 5.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) I_LWEQ PF01608.17 GAP88768.1 - 5.1 7.3 14.2 0.29 11.3 8.5 1.9 2 0 0 2 2 2 0 I/LWEQ domain Ras PF00071.22 GAP88769.1 - 8.6e-59 197.8 0.2 9.9e-59 197.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP88769.1 - 4.6e-36 123.7 0.2 7.8e-36 122.9 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP88769.1 - 8.9e-16 57.8 0.0 1.1e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAP88769.1 - 4.6e-07 29.6 0.0 6.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 GAP88769.1 - 7.2e-07 28.8 0.0 8.5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAP88769.1 - 2.6e-06 27.5 0.0 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP88769.1 - 1.7e-05 24.8 1.2 0.06 13.2 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 GAP88769.1 - 0.02 15.3 0.2 0.034 14.5 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 GAP88769.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein GbpA_2 PF18416.1 GAP88769.1 - 0.15 12.4 1.3 5.8 7.3 0.0 2.3 1 1 1 2 2 2 0 N-acetylglucosamine binding protein domain 2 AAA_22 PF13401.6 GAP88769.1 - 0.15 12.4 0.0 4.9 7.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain Syja_N PF02383.18 GAP88770.1 - 2.7e-89 299.7 0.0 3.4e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain BTB PF00651.31 GAP88771.1 - 5.2e-08 33.1 0.0 3.2e-07 30.6 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain PCI PF01399.27 GAP88772.1 - 3.3e-13 50.0 0.0 6.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 PCI domain Ribosomal_L18A PF01775.17 GAP88773.1 - 2.1e-55 186.0 0.3 2.6e-55 185.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Fungal_trans PF04082.18 GAP88774.1 - 9.2e-21 74.1 0.1 1.9e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_3 PF13302.7 GAP88775.1 - 1e-31 110.5 0.0 1.4e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP88775.1 - 0.04 13.9 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_1 PF00583.25 GAP88775.1 - 0.052 13.8 0.0 0.66 10.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF1772 PF08592.11 GAP88776.1 - 3.5e-27 95.4 3.1 5.5e-27 94.8 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) zf-C2H2 PF00096.26 GAP88780.1 - 0.0029 18.0 8.9 0.027 14.9 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP88780.1 - 0.0031 18.2 8.1 0.22 12.5 1.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger HRDC PF00570.23 GAP88782.1 - 3.5e-21 75.0 0.0 1.4e-15 57.0 0.0 2.6 2 0 0 2 2 2 2 HRDC domain DNA_pol_A_exo1 PF01612.20 GAP88782.1 - 1.6e-14 54.0 0.0 2.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HHH PF00633.23 GAP88782.1 - 0.003 17.3 0.0 0.45 10.5 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif adh_short PF00106.25 GAP88783.1 - 8.2e-34 116.8 0.0 1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88783.1 - 1.7e-22 80.2 0.1 2.3e-22 79.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88783.1 - 8.6e-09 35.6 0.1 1.2e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAP88783.1 - 0.00019 21.4 0.2 0.00093 19.1 0.1 2.1 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAP88783.1 - 0.018 14.5 0.2 0.072 12.5 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 GAP88783.1 - 0.041 13.4 0.4 2.1 7.8 0.1 2.6 2 1 1 3 3 3 0 NmrA-like family HATPase_c_5 PF14501.6 GAP88783.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 GHKL domain Nop14 PF04147.12 GAP88784.1 - 0.026 12.8 26.3 0.031 12.5 26.3 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1656 PF07869.12 GAP88784.1 - 0.11 12.6 2.7 0.18 11.9 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Vfa1 PF08432.10 GAP88784.1 - 0.12 12.7 11.6 0.18 12.1 11.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2457 PF10446.9 GAP88784.1 - 0.2 10.8 30.9 0.36 9.9 30.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 GAP88784.1 - 0.64 9.4 26.9 0.86 9.0 26.9 1.2 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 GAP88784.1 - 0.75 9.6 13.5 1.4 8.7 13.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 GAP88784.1 - 2 6.6 21.0 2.7 6.2 21.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 GAP88784.1 - 2.5 7.8 12.5 3.7 7.3 12.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BUD22 PF09073.10 GAP88784.1 - 2.7 7.2 22.2 3.6 6.8 22.2 1.1 1 0 0 1 1 1 0 BUD22 PI3K_1B_p101 PF10486.9 GAP88784.1 - 4.9 4.8 7.8 6.6 4.4 7.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RRN3 PF05327.11 GAP88784.1 - 5 5.6 20.6 6.7 5.1 20.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 LAP1C PF05609.12 GAP88784.1 - 7.2 5.6 11.6 9.7 5.2 11.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DNA_pol_phi PF04931.13 GAP88784.1 - 7.4 4.5 37.6 9.9 4.1 37.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Bromodomain PF00439.25 GAP88785.1 - 6.6e-19 67.8 0.0 1.2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.7 GAP88785.1 - 0.00018 21.4 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP88785.1 - 0.00018 21.8 0.2 0.00035 21.0 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP88785.1 - 0.00044 20.5 0.0 0.00086 19.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Rad1 PF02144.16 GAP88786.1 - 3.5e-70 236.2 0.0 4e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PRD_Mga PF08270.11 GAP88786.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain Glyco_hydro_43 PF04616.14 GAP88789.1 - 7.7e-21 74.6 1.2 1.3e-15 57.5 0.2 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 43 Di19_C PF14571.6 GAP88789.1 - 0.58 10.7 2.4 10 6.7 0.0 2.6 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Pil1 PF13805.6 GAP88790.1 - 9.6e-126 418.7 0.1 1.5e-125 418.1 0.1 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 GAP88790.1 - 0.26 10.7 3.5 0.2 11.1 0.9 1.9 1 1 1 2 2 2 0 FAM92 protein EZH2_N PF18601.1 GAP88791.1 - 6.8e-35 119.3 0.2 2e-34 117.8 0.2 1.9 1 0 0 1 1 1 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 GAP88791.1 - 1.9e-24 85.0 0.2 3.5e-24 84.2 0.2 1.4 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 GAP88791.1 - 8.8e-19 68.5 2.8 2.6e-18 67.0 0.3 3.0 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 GAP88791.1 - 3.1e-05 24.4 11.6 3.1e-05 24.4 11.6 3.7 2 1 1 3 3 3 1 CXC domain DUF3494 PF11999.8 GAP88793.1 - 1.3e-50 171.9 18.7 1.6e-50 171.7 18.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) FAD_binding_3 PF01494.19 GAP88795.1 - 3.4e-24 85.7 0.0 5.7e-24 85.0 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAP88795.1 - 2.3e-06 27.1 0.0 0.00014 21.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP88795.1 - 0.00014 21.2 0.0 0.32 10.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP88795.1 - 0.00051 19.7 0.4 0.066 12.8 0.3 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAP88795.1 - 0.0025 18.4 0.1 0.052 14.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP88795.1 - 0.0091 14.7 0.3 0.44 9.2 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 GAP88795.1 - 0.018 15.2 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 GAP88795.1 - 0.024 14.9 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 GAP88795.1 - 0.029 13.6 0.7 0.045 13.0 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 GAP88795.1 - 0.048 12.7 0.1 0.15 11.1 0.0 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAP88795.1 - 0.14 11.2 0.2 1.1 8.3 0.0 2.2 1 1 2 3 3 3 0 FAD binding domain Ank_2 PF12796.7 GAP88797.1 - 1.3e-15 57.7 0.0 2.1e-09 37.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88797.1 - 6.7e-10 39.3 0.3 0.00015 22.2 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) TPR_12 PF13424.6 GAP88797.1 - 1.2e-09 38.4 3.9 9.8e-06 25.8 1.0 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat CorA PF01544.18 GAP88797.1 - 1.5e-08 34.4 0.7 3.1e-08 33.3 0.7 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ank_3 PF13606.6 GAP88797.1 - 7.7e-07 29.0 0.4 3.6 8.5 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAP88797.1 - 1.6e-06 28.2 0.3 0.00067 19.9 0.2 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAP88797.1 - 0.00023 21.5 0.0 2.5 8.7 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat SKG6 PF08693.10 GAP88797.1 - 0.033 13.6 1.8 0.077 12.4 1.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TPR_10 PF13374.6 GAP88797.1 - 0.062 13.2 2.2 23 5.0 0.2 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAP88797.1 - 0.16 12.1 0.9 2.4 8.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_11 PF00457.17 GAP88798.1 - 5.9e-77 257.3 21.5 6.9e-77 257.1 21.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 XPG_N PF00752.17 GAP88799.1 - 8.6e-33 112.8 0.0 2.3e-32 111.5 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 GAP88799.1 - 6e-26 90.6 0.0 2.4e-25 88.7 0.0 2.1 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 GAP88799.1 - 0.012 15.4 2.0 0.055 13.4 2.0 2.3 1 0 0 1 1 1 0 Ubiquitin interaction motif 5_3_exonuc PF01367.20 GAP88799.1 - 0.015 15.9 0.0 0.053 14.1 0.0 2.0 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold LSM PF01423.22 GAP88800.1 - 3.4e-10 39.5 0.0 5.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 GAP88800.1 - 0.032 14.4 0.1 0.092 12.9 0.1 1.8 1 1 0 1 1 1 0 Ataxin 2 SM domain GH43_C2 PF17851.1 GAP88801.1 - 1.4e-28 100.0 0.0 2.1e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_43 PF04616.14 GAP88801.1 - 8.6e-22 77.8 0.1 1.6e-21 76.9 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Aldedh PF00171.22 GAP88802.1 - 6.8e-131 437.0 0.4 8.4e-131 436.6 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 GAP88803.1 - 5.9e-52 176.6 0.7 7.5e-52 176.2 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP88803.1 - 1.1e-44 152.3 1.6 1.3e-44 152.0 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP88803.1 - 3.1e-12 46.8 1.2 4.5e-12 46.2 1.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP88803.1 - 0.0026 17.2 0.3 0.0048 16.4 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP88803.1 - 0.064 12.6 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 GAP88803.1 - 0.11 12.9 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding APH PF01636.23 GAP88805.1 - 1.8e-15 57.6 0.0 3.4e-15 56.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 GAP88805.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 GAP88805.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cellulase PF00150.18 GAP88806.1 - 2.1e-11 43.8 4.6 3.3e-11 43.2 4.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Laminin_G_3 PF13385.6 GAP88806.1 - 0.0047 17.1 0.4 0.018 15.2 0.4 2.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily His_Phos_2 PF00328.22 GAP88807.1 - 3e-16 59.8 0.0 2.5e-12 46.9 0.0 3.5 2 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) Flavi_propep PF01570.17 GAP88807.1 - 0.078 12.9 0.2 0.46 10.5 0.1 2.2 2 0 0 2 2 2 0 Flavivirus polyprotein propeptide LSM PF01423.22 GAP88810.1 - 4.6e-18 64.7 0.2 5.9e-18 64.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.7 GAP88811.1 - 2.3e-14 53.2 0.0 5.3e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ATPase expression PIG-L PF02585.17 GAP88812.1 - 9.1e-28 97.5 0.0 1.5e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase AbbA_antirepres PF14156.6 GAP88813.1 - 0.041 13.8 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 Antirepressor AbbA FAM27 PF15832.5 GAP88814.1 - 0.015 15.8 0.3 0.021 15.3 0.3 1.2 1 0 0 1 1 1 0 FAM27 D and E protein family DUF3915 PF13054.6 GAP88814.1 - 0.15 12.0 1.4 0.23 11.5 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Sugar_tr PF00083.24 GAP88816.1 - 3.2e-84 283.4 19.8 3.7e-84 283.2 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP88816.1 - 2.4e-21 76.0 50.0 2.1e-15 56.5 22.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 GAP88817.1 - 2.2e-48 165.2 0.0 3.1e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 GAP88818.1 - 1.4e-05 24.8 0.0 0.00015 21.4 0.0 2.1 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 GAP88818.1 - 5.3e-05 23.2 0.1 0.00022 21.2 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 GAP88818.1 - 0.0078 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Asp PF00026.23 GAP88819.1 - 9.1e-62 209.3 0.6 1.1e-61 209.0 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP88819.1 - 1.5e-16 61.1 0.3 9.1e-16 58.6 0.3 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAP88819.1 - 0.033 14.8 1.1 3.7 8.3 0.1 3.1 3 0 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.6 GAP88819.1 - 0.094 13.3 1.0 2.5 8.7 0.1 3.0 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease NUDIX PF00293.28 GAP88820.1 - 2.7e-18 66.3 0.1 2.7e-18 66.3 0.1 1.4 2 0 0 2 2 2 1 NUDIX domain NUDIX_4 PF14815.6 GAP88820.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain SSP160 PF06933.11 GAP88820.1 - 2.3 6.3 7.6 2.7 6.1 7.6 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 COX5B PF01215.19 GAP88821.1 - 6.4e-57 190.8 0.0 8.5e-57 190.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 GAP88821.1 - 0.035 13.9 0.5 8.3 6.3 0.2 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger SUIM_assoc PF16619.5 GAP88822.1 - 0.01 15.9 0.7 0.01 15.9 0.7 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 SRPRB PF09439.10 GAP88822.1 - 0.24 10.8 0.6 0.39 10.1 0.6 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_S6 PF01250.17 GAP88823.1 - 1.3e-21 76.6 0.0 1.5e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 Cullin_binding PF03556.15 GAP88824.1 - 4.7e-31 107.7 2.8 9e-31 106.8 2.8 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 GAP88824.1 - 3.2e-09 36.5 0.0 2.5e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 UBA-like domain PX PF00787.24 GAP88825.1 - 1.4e-16 60.5 0.0 3e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 PX domain Ribosomal_L27A PF00828.19 GAP88826.1 - 6.9e-33 114.1 1.3 1e-32 113.5 1.3 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A p450 PF00067.22 GAP88827.1 - 2.9e-58 197.7 0.0 3.8e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAP88828.1 - 1.1e-12 47.5 9.9 1.4e-12 47.2 9.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CRCB PF02537.15 GAP88829.1 - 2.9e-34 117.2 12.1 1.3e-20 73.5 7.3 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) MFS_1 PF07690.16 GAP88829.1 - 3.7e-06 26.1 0.7 3.7e-06 26.1 0.7 3.0 2 1 1 3 3 3 1 Major Facilitator Superfamily UPRTase PF14681.6 GAP88830.1 - 7.7e-50 169.2 0.0 8.6e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 GAP88830.1 - 9e-06 25.3 0.0 9.7e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain P5CR_dimer PF14748.6 GAP88830.1 - 0.023 15.0 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Pribosyl_synth PF14572.6 GAP88830.1 - 0.024 14.7 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain NAD_binding_10 PF13460.6 GAP88830.1 - 0.028 14.3 0.0 0.036 14.0 0.0 1.1 1 0 0 1 1 1 0 NAD(P)H-binding PRTase_2 PF15609.6 GAP88830.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase DNA_ligase_A_M PF01068.21 GAP88831.1 - 1.4e-43 148.9 0.0 4.9e-43 147.1 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAP88831.1 - 4.1e-38 131.4 0.0 1e-37 130.1 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 GAP88831.1 - 3e-18 66.0 0.0 7e-11 42.4 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 GAP88831.1 - 3.5e-17 63.2 0.0 9.7e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 RNA ligase DNA_ligase_A_C PF04679.15 GAP88831.1 - 4.1e-13 49.8 0.0 1.3e-12 48.2 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 GAP88831.1 - 7.2e-12 45.5 0.0 2.7e-09 37.3 0.0 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 GAP88831.1 - 0.0043 17.3 0.0 4.5 7.6 0.0 2.7 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 GAP88831.1 - 0.058 13.3 0.0 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain PIF1 PF05970.14 GAP88832.1 - 1.9e-60 205.0 0.1 3.9e-46 157.9 0.0 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 GAP88832.1 - 2.2e-22 79.7 0.0 4.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAP88832.1 - 6.5e-11 42.8 0.0 2.1e-10 41.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 GAP88832.1 - 3e-07 30.8 0.0 1.6e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAP88832.1 - 1.1e-05 25.1 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 GAP88832.1 - 5e-05 23.8 0.0 0.00013 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 GAP88832.1 - 0.00046 20.6 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.14 GAP88832.1 - 0.0013 16.7 0.1 0.0042 15.1 0.0 1.7 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 GAP88832.1 - 0.0016 18.2 0.0 0.0047 16.7 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 GAP88832.1 - 0.0032 18.0 0.0 0.0082 16.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter T2SSE PF00437.20 GAP88832.1 - 0.0032 16.6 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.22 GAP88832.1 - 0.019 15.3 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 GAP88832.1 - 0.025 14.3 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 GAP88832.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 GAP88832.1 - 0.041 13.8 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 GAP88832.1 - 0.046 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 GAP88832.1 - 0.055 13.3 2.8 0.058 13.2 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 GAP88832.1 - 0.071 13.1 0.2 0.34 10.9 0.2 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 GAP88832.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.15 GAP88832.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 GAP88832.1 - 0.099 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 GAP88832.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.21 GAP88832.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 GAP88832.1 - 0.13 12.3 0.0 0.5 10.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAP88832.1 - 0.13 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SH3_13 PF18335.1 GAP88832.1 - 0.19 11.6 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Zip PF02535.22 GAP88833.1 - 9.7e-66 222.3 1.4 1.2e-65 222.0 1.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MDM10 PF12519.8 GAP88834.1 - 5.7e-160 533.2 0.0 2.7e-159 531.0 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 GAP88834.1 - 0.0013 18.2 0.0 1.3 8.4 0.1 2.7 3 0 0 3 3 3 2 Eukaryotic porin adh_short PF00106.25 GAP88835.1 - 1.9e-47 161.3 0.2 2.3e-47 161.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88835.1 - 2.2e-34 119.1 0.2 3.9e-34 118.2 0.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88835.1 - 2e-06 27.9 0.0 2.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP88835.1 - 2.7e-06 27.0 0.2 9.5e-06 25.2 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAP88835.1 - 0.00014 21.3 0.0 0.00019 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 GAP88835.1 - 0.001 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 GAP88835.1 - 0.005 16.0 0.1 0.014 14.6 0.1 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain HET PF06985.11 GAP88836.1 - 1.5e-27 96.7 0.0 2.5e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SERTA PF06031.13 GAP88836.1 - 0.076 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 SERTA motif Ank_2 PF12796.7 GAP88837.1 - 3.5e-83 274.3 6.6 5.6e-13 49.3 0.0 10.3 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88837.1 - 3.6e-65 215.5 7.4 1.3e-08 35.2 0.0 13.0 9 2 3 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88837.1 - 2.8e-57 183.9 0.4 0.00072 19.8 0.1 17.1 16 0 0 16 16 16 12 Ankyrin repeat Ank PF00023.30 GAP88837.1 - 1.1e-51 171.1 28.0 4.5e-05 23.7 0.0 16.6 17 0 0 17 17 17 12 Ankyrin repeat Ank_5 PF13857.6 GAP88837.1 - 9.5e-45 150.1 14.5 7.1e-06 26.2 0.1 13.7 8 3 8 16 16 16 10 Ankyrin repeats (many copies) CorA PF01544.18 GAP88837.1 - 1.9e-07 30.7 1.9 3.8e-07 29.7 1.9 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein KleE PF17394.2 GAP88838.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein AMP-binding PF00501.28 GAP88839.1 - 4.4e-65 219.9 0.0 6.9e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAP88839.1 - 5.2e-12 45.9 0.0 1.1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 GAP88839.1 - 4.1e-08 32.7 5.5 0.0013 18.4 0.1 5.0 5 0 0 5 5 5 3 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 GAP88839.1 - 0.0013 19.7 0.1 1.2 10.2 0.1 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain DUF3439 PF11921.8 GAP88839.1 - 0.37 10.8 15.3 0.14 12.1 6.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) LVIVD PF08309.11 GAP88841.1 - 0.0079 15.5 0.8 0.025 13.9 0.2 2.1 2 0 0 2 2 2 1 LVIVD repeat DUF3328 PF11807.8 GAP88842.1 - 1.3e-21 77.4 0.4 2.8e-21 76.3 0.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Ribosomal_S19e PF01090.19 GAP88843.1 - 9.1e-60 200.3 0.2 1e-59 200.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Amino_oxidase PF01593.24 GAP88844.1 - 2.3e-58 198.6 0.8 1.2e-56 193.0 0.8 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAP88844.1 - 1.2e-07 31.8 0.1 3e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 GAP88844.1 - 2.4e-05 23.7 0.3 0.053 12.8 0.3 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 GAP88844.1 - 0.00019 20.8 0.1 0.04 13.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP88844.1 - 0.0034 16.7 0.3 0.023 14.0 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP88844.1 - 0.012 16.1 0.4 0.51 10.9 0.3 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 GAP88844.1 - 0.016 15.3 0.1 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 GAP88844.1 - 0.04 13.2 0.4 0.084 12.1 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 GAP88844.1 - 0.1 12.2 1.3 0.26 10.8 0.7 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.21 GAP88844.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 ThiF family CorA PF01544.18 GAP88845.1 - 1.1e-24 87.3 11.3 1.5e-20 73.7 6.3 3.1 3 1 0 3 3 3 2 CorA-like Mg2+ transporter protein Alk_phosphatase PF00245.20 GAP88846.1 - 6.7e-106 354.7 0.0 8e-106 354.5 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 GAP88846.1 - 2.8e-05 23.6 0.0 6.2e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Metalloenzyme superfamily Phosphodiest PF01663.22 GAP88846.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase F-box-like PF12937.7 GAP88847.1 - 0.023 14.6 0.5 0.13 12.2 0.1 2.4 2 0 0 2 2 2 0 F-box-like Rad9 PF04139.13 GAP88848.1 - 2.5e-48 164.7 0.1 3e-48 164.4 0.1 1.1 1 0 0 1 1 1 1 Rad9 RCC1 PF00415.18 GAP88849.1 - 5.6e-29 100.5 18.0 6.9e-13 49.0 0.0 7.1 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAP88849.1 - 7.2e-17 60.7 26.8 6.8e-06 25.7 0.1 5.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PapC_C PF13953.6 GAP88849.1 - 0.013 15.3 0.2 0.47 10.3 0.0 2.7 2 0 0 2 2 2 0 PapC C-terminal domain RNA_helicase PF00910.22 GAP88849.1 - 0.049 14.0 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase PDH PF02153.17 GAP88850.1 - 4.4e-15 55.4 0.0 6.2e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 GAP88850.1 - 5.2e-06 26.9 0.0 1.3e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 GAP88850.1 - 1.7e-05 25.0 0.0 3.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 GAP88850.1 - 0.00037 20.2 0.0 0.00066 19.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 GAP88850.1 - 0.0014 18.0 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAP88850.1 - 0.02 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 GAP88850.1 - 0.026 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 GAP88850.1 - 0.034 14.0 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 GAP88851.1 - 7.4e-94 315.2 5.4 8.5e-94 315.0 5.4 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAP88851.1 - 9.3e-08 31.7 0.2 1.8e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAP88851.1 - 5.7e-07 29.7 0.5 2.4e-06 27.7 0.5 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAP88851.1 - 1.9e-05 24.0 0.7 0.0041 16.4 0.3 2.6 3 0 0 3 3 3 2 Thi4 family FAD_oxidored PF12831.7 GAP88851.1 - 0.00011 21.7 0.7 0.0002 20.9 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP88851.1 - 0.00013 21.3 1.4 0.00061 19.1 0.2 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP88851.1 - 0.00015 21.0 0.4 0.0007 18.8 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 GAP88851.1 - 0.0042 15.8 0.2 0.0042 15.8 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 GAP88851.1 - 0.005 16.5 11.9 0.052 13.1 11.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase EAR PF07897.11 GAP88851.1 - 0.012 15.2 0.2 0.48 10.1 0.0 2.5 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression Lycopene_cycl PF05834.12 GAP88851.1 - 0.095 11.7 0.5 0.17 10.9 0.5 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Glu_dehyd_C PF16912.5 GAP88851.1 - 0.14 11.6 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 GAP88851.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 GAP88851.1 - 0.2 10.9 0.4 0.33 10.2 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP88851.1 - 0.35 11.5 1.4 0.94 10.1 0.7 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 GAP88852.1 - 2.5e-41 141.0 0.0 6.1e-26 90.9 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 GAP88852.1 - 0.051 13.9 0.0 0.18 12.2 0.1 1.8 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 GAP88852.1 - 0.058 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP88852.1 - 0.064 12.9 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 GAP88852.1 - 0.16 12.6 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 GAP88852.1 - 0.17 11.1 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3328 PF11807.8 GAP88853.1 - 5.4e-19 68.8 2.8 6.9e-19 68.5 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 GAP88854.1 - 2.6e-08 33.9 0.0 3.5e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_M14 PF00246.24 GAP88856.1 - 8.1e-76 255.6 0.4 1.2e-75 255.0 0.4 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Ricin_B_lectin PF00652.22 GAP88857.1 - 3.7e-13 49.8 0.0 0.00018 21.7 0.0 4.2 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain FIST_C PF10442.9 GAP88857.1 - 0.065 13.2 0.0 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 FIST C domain CDtoxinA PF03498.14 GAP88857.1 - 0.12 11.9 0.1 1 9.0 0.0 2.5 2 1 1 3 3 3 0 Cytolethal distending toxin A/C domain SOG2 PF10428.9 GAP88857.1 - 3.3 6.8 11.9 4.8 6.3 11.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein NmrA PF05368.13 GAP88858.1 - 2.1e-35 122.4 0.0 2.5e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP88858.1 - 2.3e-13 50.4 0.1 2.7e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP88858.1 - 2.3e-05 24.0 0.0 4.8e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAP88858.1 - 0.023 13.7 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAP88858.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 GAP88858.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 GAP88858.1 - 0.096 12.6 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 KR domain DUF1772 PF08592.11 GAP88859.1 - 2.1e-23 83.2 0.1 2.3e-23 83.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) p450 PF00067.22 GAP88860.1 - 4e-45 154.4 0.0 7e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Mucin PF01456.17 GAP88860.1 - 1.2 9.1 14.0 1.9 8.5 14.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 GAP88860.1 - 2.4 6.0 7.4 3.4 5.5 7.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAD_binding_2 PF00890.24 GAP88861.1 - 2.2e-07 30.3 0.0 2.5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAP88861.1 - 7e-06 25.5 0.1 0.0036 16.6 0.0 1.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAP88861.1 - 2.3e-05 23.8 0.2 2.9e-05 23.5 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP88861.1 - 6.3e-05 22.3 0.0 6.5e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP88861.1 - 7e-05 23.0 0.1 0.00014 22.1 0.0 1.5 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAP88861.1 - 0.00012 21.6 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 GAP88861.1 - 0.0004 19.6 0.0 0.00044 19.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 GAP88861.1 - 0.00045 19.0 0.1 0.00056 18.7 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 GAP88861.1 - 0.012 14.8 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 GAP88861.1 - 0.018 14.6 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAP88861.1 - 0.025 13.9 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GAP88861.1 - 0.027 15.0 0.0 0.034 14.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAP88861.1 - 0.092 11.8 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 GAP88861.1 - 0.096 12.6 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 GAP88862.1 - 2.4e-12 46.8 0.9 3.1e-05 23.4 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAP88862.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP88862.1 - 0.043 13.1 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pro-kuma_activ PF09286.11 GAP88863.1 - 3.6e-37 127.8 0.0 5.8e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAP88863.1 - 7.4e-08 32.0 1.4 1.4e-07 31.1 1.4 1.4 1 0 0 1 1 1 1 Subtilase family Arrestin_C PF02752.22 GAP88864.1 - 3.4e-17 63.2 0.0 2.7e-16 60.2 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAP88864.1 - 1.5e-06 28.3 0.9 0.016 15.3 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Glyco_hydro_10 PF00331.20 GAP88865.1 - 3.5e-24 85.5 0.0 4.2e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 2OG-FeII_Oxy PF03171.20 GAP88865.1 - 0.1 13.1 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Glyco_hydro_10 PF00331.20 GAP88866.1 - 2e-25 89.7 0.0 2.3e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 GAP88866.1 - 8.2e-12 44.9 17.5 8.2e-12 44.9 17.5 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain p450 PF00067.22 GAP88867.1 - 4.8e-49 167.3 0.0 6.5e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAR1 PF03101.15 GAP88868.1 - 2.2e-06 28.3 0.3 4e-06 27.4 0.3 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Snapin_Pallidin PF14712.6 GAP88868.1 - 0.0012 19.2 0.1 0.002 18.5 0.1 1.3 1 0 0 1 1 1 1 Snapin/Pallidin Sugarporin_N PF11471.8 GAP88868.1 - 0.0098 15.8 1.1 8.8 6.4 0.0 2.1 1 1 0 1 1 1 1 Maltoporin periplasmic N-terminal extension AFT PF08731.11 GAP88868.1 - 0.012 16.0 0.2 0.022 15.2 0.2 1.4 1 0 0 1 1 1 0 Transcription factor AFT XhlA PF10779.9 GAP88868.1 - 0.04 14.1 0.0 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.12 GAP88868.1 - 0.048 13.7 0.1 0.078 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 GAP88868.1 - 0.057 13.7 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain COG2 PF06148.11 GAP88868.1 - 0.092 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Matrilin_ccoil PF10393.9 GAP88868.1 - 0.11 12.4 1.4 1.6 8.6 1.3 2.4 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF913 PF06025.12 GAP88869.1 - 0.09 11.7 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) YmgD PF16456.5 GAP88869.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 YmgD protein eIF-3c_N PF05470.12 GAP88870.1 - 3.9e-176 586.9 21.1 3.9e-176 586.9 21.1 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 GAP88870.1 - 4.2e-13 49.7 0.1 1.8e-12 47.7 0.1 2.2 1 0 0 1 1 1 1 PCI domain DUF2779 PF11074.8 GAP88870.1 - 0.2 12.1 2.4 0.64 10.5 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function(DUF2779) SDA1 PF05285.12 GAP88870.1 - 3.2 7.1 38.2 5.6 6.3 38.2 1.4 1 0 0 1 1 1 0 SDA1 Peptidase_S64 PF08192.11 GAP88870.1 - 5.7 5.3 14.5 10 4.4 14.5 1.4 1 0 0 1 1 1 0 Peptidase family S64 Hemerythrin PF01814.23 GAP88871.1 - 6.1e-11 43.1 4.7 2.5e-07 31.4 1.0 2.2 2 0 0 2 2 2 2 Hemerythrin HHE cation binding domain RNA_pol_Rpc4 PF05132.14 GAP88871.1 - 0.015 15.7 1.1 0.018 15.5 0.7 1.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4746 PF15928.5 GAP88871.1 - 0.059 12.8 4.4 0.082 12.3 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNase_H2_suC PF08615.11 GAP88871.1 - 0.063 13.4 0.3 0.1 12.8 0.3 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Pox_Ag35 PF03286.14 GAP88871.1 - 0.14 12.0 4.2 0.23 11.2 4.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GOLD_2 PF13897.6 GAP88871.1 - 0.18 12.3 0.8 0.24 11.9 0.8 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF4366 PF14283.6 GAP88871.1 - 0.31 11.1 4.0 0.43 10.6 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SnoaL_4 PF13577.6 GAP88872.1 - 7.7e-08 32.5 0.0 1.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain Cellulase PF00150.18 GAP88873.1 - 2.8e-16 59.8 0.1 3.8e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 GAP88876.1 - 9.4e-18 64.2 51.5 3.2e-10 39.5 18.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.8 GAP88876.1 - 2.4 8.3 4.8 16 5.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function Acetyltransf_1 PF00583.25 GAP88877.1 - 1e-07 32.2 0.0 1.5e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP88877.1 - 0.00013 22.3 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAP88877.1 - 0.00019 21.4 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DIOX_N PF14226.6 GAP88878.1 - 2e-13 51.1 0.0 5.2e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP88878.1 - 3e-07 30.9 0.0 1.7e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 GAP88879.1 - 1.1e-25 90.0 0.0 3.7e-15 56.3 0.0 3.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88879.1 - 2.2e-18 66.3 1.0 4.9e-10 39.7 0.1 3.5 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAP88879.1 - 2.8e-17 62.3 3.2 2.2e-05 24.7 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 GAP88879.1 - 4.7e-15 54.2 1.2 0.0007 19.9 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 GAP88879.1 - 1.9e-10 40.8 4.5 0.00093 19.5 0.2 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) zf-C2H2_6 PF13912.6 GAP88880.1 - 0.13 12.3 2.1 0.8 9.8 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger HET PF06985.11 GAP88881.1 - 7.7e-11 42.5 4.5 6.6e-08 33.0 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PTCB-BRCT PF12738.7 GAP88882.1 - 5.3e-43 144.8 0.0 4.3e-21 74.6 0.0 3.3 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 GAP88882.1 - 9.2e-34 115.7 0.1 1.9e-12 47.4 0.0 4.5 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAP88882.1 - 7.1e-19 68.0 0.1 4.2e-06 27.1 0.0 4.1 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 GAP88882.1 - 1.6e-07 31.5 0.1 0.032 14.5 0.0 4.2 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 GAP88882.1 - 0.011 15.7 0.0 12 5.8 0.0 3.6 4 0 0 4 4 4 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 GAP88882.1 - 0.012 15.6 0.5 5.3 7.2 0.1 3.4 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Utp8 PF10395.9 GAP88884.1 - 6.6e-08 31.5 0.1 3.2e-07 29.3 0.1 1.9 1 1 0 1 1 1 1 Utp8 family AAA PF00004.29 GAP88885.1 - 3e-08 34.1 0.3 1.8e-07 31.7 0.3 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 GAP88885.1 - 1.3e-05 25.2 0.2 0.00095 19.1 0.1 2.9 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 GAP88885.1 - 0.0012 19.2 0.0 0.0041 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAP88885.1 - 0.018 15.0 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP88885.1 - 0.026 14.8 0.0 0.093 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 GAP88885.1 - 0.028 13.6 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 GAP88885.1 - 0.037 14.0 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAP88885.1 - 0.045 13.3 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 GAP88885.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IF2_N PF04760.15 GAP88885.1 - 0.067 13.0 0.2 3.2 7.6 0.1 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region ABC_tran PF00005.27 GAP88885.1 - 0.073 13.6 0.0 0.45 11.0 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 GAP88885.1 - 0.1 12.6 0.0 0.59 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAP88885.1 - 0.11 13.0 0.0 0.46 11.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAP88885.1 - 0.19 11.6 0.0 19 5.1 0.0 2.4 2 0 0 2 2 2 0 NTPase DUF1848 PF08902.11 GAP88885.1 - 0.19 11.4 0.0 1.1 8.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) Pec_lyase_C PF00544.19 GAP88886.1 - 4.3e-24 85.3 0.0 8.2e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Pectate lyase His_Phos_2 PF00328.22 GAP88887.1 - 8.4e-26 91.2 0.0 1.1e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SIR2 PF02146.17 GAP88888.1 - 1.6e-34 119.3 0.0 4.5e-34 117.9 0.0 1.7 1 1 0 1 1 1 1 Sir2 family DUF1936 PF09151.10 GAP88888.1 - 0.26 11.2 1.4 8.9 6.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) DUF3176 PF11374.8 GAP88889.1 - 0.03 14.5 4.2 0.081 13.1 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) PDR_CDR PF06422.12 GAP88889.1 - 0.072 13.0 1.5 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 CDR ABC transporter SUR7 PF06687.12 GAP88889.1 - 2.2 7.9 8.0 0.53 9.9 0.1 2.6 3 0 0 3 3 3 0 SUR7/PalI family DUF5453 PF17534.2 GAP88890.1 - 0.064 13.2 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5453) Fungal_trans PF04082.18 GAP88891.1 - 0.00015 20.9 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NMO PF03060.15 GAP88893.1 - 1.2e-35 123.4 1.5 7e-31 107.8 0.3 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 GAP88893.1 - 1e-08 34.6 5.5 1.6e-08 34.0 5.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 GAP88893.1 - 3.5e-07 29.5 4.3 0.0013 17.8 4.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 GAP88893.1 - 2.2e-05 23.8 2.5 3.2e-05 23.2 2.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase PRIMA1 PF16101.5 GAP88893.1 - 0.0078 16.2 4.4 0.015 15.4 4.4 1.5 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 CAP_N PF01213.19 GAP88893.1 - 0.092 12.2 6.0 0.14 11.7 6.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 GAP88893.1 - 0.89 9.6 5.1 1.6 8.7 5.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Cyclin PF08613.11 GAP88894.1 - 1.9e-13 51.1 0.0 3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAP88894.1 - 0.0076 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Acetyltransf_3 PF13302.7 GAP88896.1 - 5.7e-23 82.1 0.0 7.2e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3433 PF11915.8 GAP88897.1 - 2.9e-11 43.7 7.4 1e-06 29.1 0.4 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) Shadoo PF14999.6 GAP88898.1 - 0.099 12.7 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective MFS_1 PF07690.16 GAP88899.1 - 3.7e-33 114.9 52.5 1.4e-32 113.0 39.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 GAP88899.1 - 0.011 16.0 0.3 0.011 16.0 0.3 4.2 2 2 2 4 4 4 0 Domain of unknown function (DUF1772) DUF2776 PF10951.8 GAP88899.1 - 1.1 8.5 8.2 0.17 11.1 2.7 2.3 2 2 0 2 2 2 0 Protein of unknown function (DUF2776) DUF3328 PF11807.8 GAP88900.1 - 1.5e-27 96.8 0.8 2.3e-27 96.2 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3446 PF11928.8 GAP88901.1 - 2.6 8.4 11.4 5.6 7.3 2.0 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain EF-hand_7 PF13499.6 GAP88902.1 - 2e-26 92.2 0.0 7.4e-17 61.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAP88902.1 - 2.6e-22 76.7 2.0 4.7e-09 35.2 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 GAP88902.1 - 5.5e-19 67.8 0.9 2.5e-11 43.3 0.1 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 GAP88902.1 - 3e-16 57.9 0.8 0.00057 19.6 0.0 4.3 3 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAP88902.1 - 1.2e-10 40.4 4.4 0.00014 21.2 0.3 3.8 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 GAP88902.1 - 4.3e-07 30.2 0.0 0.00016 22.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 GAP88902.1 - 4.3e-07 29.8 0.0 0.00026 20.9 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 GAP88902.1 - 3.7e-05 23.6 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) DUF3349 PF11829.8 GAP88902.1 - 0.001 19.8 0.0 0.095 13.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3349) SPARC_Ca_bdg PF10591.9 GAP88902.1 - 0.21 11.9 0.0 18 5.7 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Aldo_ket_red PF00248.21 GAP88903.1 - 2.5e-38 132.0 0.0 6.7e-36 124.0 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family eRF1_1 PF03463.15 GAP88904.1 - 1.1e-44 151.6 0.0 1.8e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 GAP88904.1 - 1.3e-19 70.9 0.0 1.9e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAP88904.1 - 9.1e-19 68.0 0.0 1.8e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 WD40 PF00400.32 GAP88905.1 - 8.8e-27 92.8 15.9 1.6e-06 28.8 0.1 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 GAP88905.1 - 0.4 9.6 1.2 27 3.6 0.1 3.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CAF1C_H4-bd PF12265.8 GAP88906.1 - 8.6e-13 48.3 0.0 2.5e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GAP88906.1 - 8.9e-13 48.5 9.0 6.7e-07 29.9 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP88906.1 - 2.4e-06 27.8 0.7 0.0042 17.3 0.1 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain K_channel_TID PF07941.11 GAP88906.1 - 0.022 15.2 3.9 0.065 13.7 3.9 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Nup160 PF11715.8 GAP88906.1 - 0.068 11.8 2.4 0.15 10.7 0.4 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ILVD_EDD PF00920.21 GAP88907.1 - 8.4e-197 654.9 0.8 9.5e-197 654.7 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family Lactonase PF10282.9 GAP88908.1 - 1.5e-41 142.8 0.0 3.1e-24 85.9 0.0 2.0 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller DUF5035 PF16438.5 GAP88908.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5035) Glyco_hydro_16 PF00722.21 GAP88909.1 - 2.7e-44 150.7 6.2 2.7e-44 150.7 6.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 GAP88909.1 - 0.054 14.0 12.9 0.13 12.8 12.9 1.6 1 0 0 1 1 1 0 Chitin recognition protein NUDIX PF00293.28 GAP88910.1 - 0.00034 20.7 0.1 0.00078 19.5 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain Myb_DNA-binding PF00249.31 GAP88911.1 - 2.7e-16 59.5 1.4 2.2e-09 37.4 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP88911.1 - 1.8e-10 40.9 0.4 0.00026 21.2 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Ribosomal_L27A PF00828.19 GAP88912.1 - 8.8e-13 49.0 0.0 9.5e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A XRN_M PF17846.1 GAP88914.1 - 0.2 10.6 0.1 0.35 9.8 0.1 1.3 1 0 0 1 1 1 0 Xrn1 helical domain OHCU_decarbox PF09349.10 GAP88915.1 - 2.4e-41 141.8 0.0 4e-41 141.1 0.0 1.3 1 1 0 1 1 1 1 OHCU decarboxylase DEC-1_N PF04625.13 GAP88915.1 - 0.052 12.6 1.0 0.059 12.4 1.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Prp19 PF08606.11 GAP88916.1 - 4e-32 110.0 2.2 9.3e-32 108.8 2.2 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 GAP88916.1 - 5.1e-08 33.1 0.0 0.0085 16.4 0.0 5.0 2 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAP88916.1 - 1.3e-07 32.1 0.0 0.21 12.5 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat VID27 PF08553.10 GAP88916.1 - 0.0019 17.3 0.2 0.004 16.2 0.0 1.5 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain V_ATPase_I_N PF18670.1 GAP88916.1 - 0.0038 17.6 1.2 0.0071 16.7 0.2 2.0 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain PQQ_2 PF13360.6 GAP88916.1 - 0.0054 16.3 5.1 0.03 13.9 0.9 2.2 1 1 1 2 2 2 1 PQQ-like domain Coatomer_WDAD PF04053.14 GAP88916.1 - 0.0062 15.6 0.1 0.048 12.7 0.0 2.0 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 GAP88916.1 - 0.014 15.3 0.1 2.8 7.8 0.0 2.9 1 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A zf-Nse PF11789.8 GAP88916.1 - 0.029 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 GAP88916.1 - 0.033 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 U-box domain Prok-RING_4 PF14447.6 GAP88917.1 - 0.0041 16.9 1.7 0.014 15.3 0.4 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAP88917.1 - 0.0065 16.5 0.4 0.014 15.4 0.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAP88917.1 - 0.017 15.0 4.7 0.045 13.7 4.7 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAP88917.1 - 0.053 13.4 0.6 0.053 13.4 0.6 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP88917.1 - 0.73 10.2 3.0 0.51 10.7 0.7 1.8 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 GAP88917.1 - 0.83 9.6 3.5 0.52 10.2 0.7 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP88917.1 - 1.1 9.2 3.4 2.5 8.0 3.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Presenilin PF01080.17 GAP88917.1 - 3.4 6.4 19.5 0.42 9.3 3.5 2.3 2 0 0 2 2 2 0 Presenilin SDA1 PF05285.12 GAP88917.1 - 3.5 7.0 35.5 0.039 13.4 24.9 2.1 2 0 0 2 2 2 0 SDA1 OPT PF03169.15 GAP88919.1 - 3e-90 303.6 44.0 3.5e-90 303.4 44.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4449 PF14613.6 GAP88921.1 - 9.5e-67 224.2 3.1 9.5e-67 224.2 3.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Activator-TraM PF11657.8 GAP88921.1 - 1 9.2 5.7 0.55 10.1 2.7 2.1 2 0 0 2 2 2 0 Transcriptional activator TraM Exonuc_VII_L PF02601.15 GAP88921.1 - 3.1 7.3 9.7 2.8 7.4 1.0 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit HAD_2 PF13419.6 GAP88922.1 - 3.2e-06 27.3 0.0 4.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP88922.1 - 1.8e-05 25.1 0.0 0.0014 19.0 0.0 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP88922.1 - 0.031 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like EB1 PF03271.17 GAP88923.1 - 1.1e-16 60.7 2.7 2.2e-16 59.8 2.7 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 GAP88923.1 - 1.7e-05 24.9 0.7 3.2e-05 24.1 0.7 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF2183 PF09949.9 GAP88924.1 - 1.3e-30 105.6 0.0 3.2e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 GAP88924.1 - 0.0013 18.2 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DEAD PF00270.29 GAP88925.1 - 5e-46 156.7 0.0 8.7e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP88925.1 - 5.2e-29 100.8 0.6 4.3e-28 97.9 0.2 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 GAP88925.1 - 5.4e-06 25.4 1.1 4.9e-05 22.3 0.1 2.4 1 1 2 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 GAP88925.1 - 0.00063 19.8 0.0 0.0058 16.7 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Y1_Tnp PF01797.16 GAP88926.1 - 0.15 12.1 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Transposase IS200 like DUF3400 PF11880.8 GAP88927.1 - 0.12 11.9 0.4 0.33 10.5 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) p450 PF00067.22 GAP88928.1 - 1.2e-64 218.8 0.0 1.4e-64 218.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SRR1 PF07985.12 GAP88929.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 SRR1 ADH_zinc_N PF00107.26 GAP88930.1 - 6.4e-23 81.2 3.5 1e-22 80.5 3.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP88930.1 - 8.8e-20 72.1 0.5 1.4e-19 71.4 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP88930.1 - 1.3e-09 37.8 0.0 4.3e-08 33.0 0.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ank_2 PF12796.7 GAP88931.1 - 9.5e-80 263.3 24.5 6.7e-16 58.7 0.5 8.2 2 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88931.1 - 9.8e-61 201.4 22.0 7.2e-09 36.0 0.1 10.0 3 2 9 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 GAP88931.1 - 7.7e-59 193.7 10.3 7.5e-07 29.3 0.1 13.5 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 GAP88931.1 - 1.6e-53 172.4 11.7 0.00024 21.3 0.0 13.7 13 1 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 GAP88931.1 - 1.3e-39 133.7 14.9 6.4e-09 35.9 0.1 9.6 2 2 7 11 11 11 10 Ankyrin repeats (many copies) p450 PF00067.22 GAP88932.1 - 6.8e-29 100.9 0.0 2.5e-27 95.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.23 GAP88933.1 - 2.6e-25 88.8 0.4 4e-25 88.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP88933.1 - 9.3e-05 22.5 0.1 0.00017 21.6 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 GAP88934.1 - 8.1e-41 140.2 0.0 4e-38 131.3 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 Chordopox_E11 PF06138.12 GAP88934.1 - 0.008 16.5 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Chordopoxvirus E11 protein adh_short PF00106.25 GAP88935.1 - 6.5e-18 64.9 0.0 1.9e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP88935.1 - 2.8e-05 23.8 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP88935.1 - 0.00021 21.2 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP88935.1 - 0.00039 20.0 0.0 0.0024 17.3 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP88935.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Cytomega_UL84 PF06284.11 GAP88937.1 - 0.19 10.1 2.9 0.27 9.7 2.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF1664 PF07889.12 GAP88938.1 - 0.0014 18.6 3.7 0.0022 18.0 1.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 GAP88938.1 - 0.0026 18.0 3.2 1.6 9.1 0.7 2.7 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DNA_primase_lrg PF04104.14 GAP88938.1 - 0.22 10.9 0.2 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit GCN5L1 PF06320.13 GAP88938.1 - 0.44 10.7 4.3 0.74 10.0 1.1 3.0 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) DUF948 PF06103.11 GAP88938.1 - 1.6 9.0 11.2 1.1 9.6 6.2 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Citrate_ly_lig PF08218.11 GAP88939.1 - 0.0015 18.3 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Citrate lyase ligase C-terminal domain DUF3220 PF11516.8 GAP88939.1 - 0.061 13.5 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) ANAPC10 PF03256.16 GAP88940.1 - 9.9e-50 168.7 0.0 1.5e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 GAP88940.1 - 0.06 13.5 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 F5/8 type C domain ERAP1_C PF11838.8 GAP88941.1 - 5.8e-86 288.9 0.1 3.5e-85 286.3 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 GAP88941.1 - 4.4e-78 261.8 5.8 7e-78 261.1 5.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 GAP88941.1 - 8.4e-48 163.0 0.9 5.8e-47 160.3 0.3 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 GAP88941.1 - 0.0017 18.3 0.1 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2808) DUF45 PF01863.17 GAP88941.1 - 0.044 13.8 0.1 0.36 10.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF45 TEX12 PF15219.6 GAP88941.1 - 0.14 12.5 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 Testis-expressed 12 PilJ PF13675.6 GAP88942.1 - 0.047 13.7 5.6 12 5.9 3.9 3.0 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3963 PF13124.6 GAP88942.1 - 0.26 11.3 0.1 0.46 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Enkurin PF13864.6 GAP88942.1 - 0.76 10.2 13.3 20 5.7 5.9 3.3 1 1 1 2 2 2 0 Calmodulin-binding CBFD_NFYB_HMF PF00808.23 GAP88943.1 - 0.00011 22.4 0.6 0.00013 22.2 0.6 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 GAP88943.1 - 0.001 19.2 0.0 0.0012 19.0 0.0 1.1 1 0 0 1 1 1 1 CENP-W protein TAFII28 PF04719.14 GAP88943.1 - 0.058 13.5 0.4 0.075 13.1 0.4 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region CDH-cyt PF16010.5 GAP88944.1 - 1.2e-47 162.0 1.2 1.9e-47 161.3 1.2 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 GAP88944.1 - 0.0021 18.3 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 DOMON domain NACHT_N PF17100.5 GAP88947.1 - 4.9e-49 167.2 0.0 4.9e-48 163.9 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 GAP88947.1 - 1.7e-45 153.5 9.9 2.5e-14 53.6 0.0 4.6 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 GAP88947.1 - 2.6e-31 106.7 11.3 1.3e-06 28.6 0.1 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 GAP88947.1 - 1.1e-30 105.6 3.4 2.7e-08 34.2 0.0 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP88947.1 - 2.5e-25 88.2 4.1 5.3e-06 26.6 0.1 5.8 1 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88947.1 - 6.5e-23 78.3 0.4 0.0012 19.2 0.0 8.8 8 0 0 8 8 8 5 Ankyrin repeat NACHT PF05729.12 GAP88947.1 - 3.8e-06 26.9 0.3 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GAP88947.1 - 8.7e-05 23.0 0.3 0.00056 20.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 GAP88947.1 - 0.014 14.9 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 GAP88947.1 - 0.1 11.8 0.1 1 8.5 0.1 2.0 1 1 1 2 2 2 0 KAP family P-loop domain AAA PF00004.29 GAP88947.1 - 0.13 12.7 0.1 0.53 10.7 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAP88947.1 - 0.14 12.5 0.0 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain PRP4 PF08799.11 GAP88949.1 - 0.075 12.6 1.3 43 3.8 0.4 3.8 3 0 0 3 3 3 0 pre-mRNA processing factor 4 (PRP4) like SWIM PF04434.17 GAP88950.1 - 0.00071 19.2 0.8 0.25 11.1 0.0 2.3 2 0 0 2 2 2 2 SWIM zinc finger DUF1635 PF07795.11 GAP88950.1 - 0.012 15.5 0.3 0.012 15.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) TFIIA PF03153.13 GAP88950.1 - 0.44 10.5 5.9 0.58 10.1 5.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 GAP88950.1 - 0.85 9.5 3.6 1.1 9.1 3.6 1.1 1 0 0 1 1 1 0 SPX domain MitMem_reg PF13012.6 GAP88951.1 - 2.8e-36 124.3 0.2 5.7e-36 123.3 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 GAP88951.1 - 2e-32 111.6 0.3 7.8e-32 109.7 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FANCI_S4 PF14678.6 GAP88951.1 - 0.083 12.0 5.0 0.18 10.9 5.0 1.5 1 1 0 1 1 1 0 FANCI solenoid 4 tRNA_bind_2 PF13725.6 GAP88951.1 - 0.11 12.2 7.2 0.04 13.6 4.8 1.5 2 0 0 2 2 2 0 Possible tRNA binding domain Connexin PF00029.19 GAP88951.1 - 0.17 11.6 3.4 0.3 10.8 3.4 1.4 1 0 0 1 1 1 0 Connexin DUF1682 PF07946.14 GAP88951.1 - 0.5 9.5 11.6 2.5 7.2 12.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) OAD_gamma PF04277.13 GAP88951.1 - 1.4 9.6 3.1 4 8.1 3.1 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3987 PF13148.6 GAP88951.1 - 2.9 6.8 8.7 4.4 6.2 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ADK PF00406.22 GAP88952.1 - 7e-59 198.3 0.0 9.3e-59 197.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 GAP88952.1 - 1.5e-24 86.9 0.2 3.5e-24 85.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.14 GAP88952.1 - 2e-17 62.9 0.0 8.8e-17 60.8 0.0 2.0 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 GAP88952.1 - 4.8e-07 30.4 0.2 3.3e-05 24.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 GAP88952.1 - 1.2e-05 25.6 0.0 0.00012 22.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF4201 PF13870.6 GAP88952.1 - 0.1 12.3 0.9 3.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4889 PF16230.5 GAP88952.1 - 0.13 12.5 0.1 0.56 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4889) HALZ PF02183.18 GAP88953.1 - 0.0017 18.5 3.3 0.0017 18.5 3.3 9.4 9 2 1 10 10 10 2 Homeobox associated leucine zipper PriCT_1 PF08708.11 GAP88953.1 - 0.08 12.7 1.7 0.73 9.6 0.1 3.3 3 1 1 4 4 4 0 Primase C terminal 1 (PriCT-1) CENP-F_leu_zip PF10473.9 GAP88953.1 - 9 6.3 82.7 0.028 14.5 15.8 5.8 2 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ank_2 PF12796.7 GAP88954.1 - 2.4e-103 338.9 23.6 8.9e-12 45.4 0.1 14.5 6 3 5 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88954.1 - 3.4e-73 241.1 32.1 1.1e-07 32.2 0.2 17.9 14 3 6 21 21 21 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP88954.1 - 1.5e-57 190.9 39.0 5.1e-06 26.7 0.0 19.1 11 5 9 21 21 21 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88954.1 - 3.7e-54 174.3 32.6 0.0018 18.6 0.0 26.4 30 0 0 30 30 30 14 Ankyrin repeat Ank PF00023.30 GAP88954.1 - 5.3e-47 156.3 55.6 0.00058 20.2 0.1 23.9 24 0 0 24 24 24 15 Ankyrin repeat SPRY PF00622.28 GAP88954.1 - 5.9e-21 74.8 1.0 2.1e-20 73.0 0.2 2.1 2 0 0 2 2 2 1 SPRY domain cEGF PF12662.7 GAP88954.1 - 0.18 11.8 0.0 0.52 10.3 0.0 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like Peptidase_S8 PF00082.22 GAP88955.1 - 8.3e-20 71.2 0.3 2e-19 69.9 0.3 1.6 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 GAP88955.1 - 0.0073 16.9 0.0 0.079 13.6 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 GAP88955.1 - 0.019 15.4 0.1 0.48 11.0 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Nop14 PF04147.12 GAP88955.1 - 7.3 4.7 15.5 13 3.9 15.5 1.3 1 0 0 1 1 1 0 Nop14-like family Inhibitor_I9 PF05922.16 GAP88956.1 - 0.033 14.9 0.0 0.051 14.2 0.0 1.4 1 1 0 1 1 1 0 Peptidase inhibitor I9 Glyco_hydro_71 PF03659.14 GAP88957.1 - 3.8e-117 391.3 0.3 4.3e-117 391.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 GAP88957.1 - 0.054 13.5 0.1 0.38 10.7 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Abhydrolase_6 PF12697.7 GAP88959.1 - 9.8e-13 49.2 0.1 1.2e-12 48.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP88959.1 - 1.2e-06 28.0 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Hydrophobin_2 PF06766.11 GAP88960.1 - 6.1e-27 93.4 9.7 7.7e-27 93.0 9.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin MFS_1 PF07690.16 GAP88961.1 - 2.2e-32 112.4 28.9 2.2e-32 112.4 28.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5315 PF17242.2 GAP88962.1 - 8e-25 86.5 0.5 2.2e-24 85.0 0.5 1.7 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) Ribosom_S12_S23 PF00164.25 GAP88963.1 - 1.9e-51 172.5 0.7 2.4e-51 172.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UbiA PF01040.18 GAP88964.1 - 2.8e-43 148.0 17.8 3.7e-43 147.6 17.8 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.22 GAP88965.1 - 2.4e-10 40.9 0.8 1.1e-09 38.7 0.2 2.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 GAP88965.1 - 3.1e-07 30.5 10.9 3.1e-07 30.5 10.9 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 GAP88965.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Bac_transf PF02397.16 GAP88966.1 - 0.15 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial sugar transferase DUF1689 PF07954.11 GAP88967.1 - 0.014 15.8 0.0 0.019 15.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1689) DUF3883 PF13020.6 GAP88968.1 - 0.0041 17.1 0.0 0.0096 15.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 GAP88968.1 - 0.0084 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_2 PF12796.7 GAP88969.1 - 2.2e-24 85.8 15.6 7e-09 36.2 2.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP88969.1 - 3.2e-18 65.8 8.0 1.2e-05 25.7 0.2 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP88969.1 - 6.4e-18 64.6 17.5 9.7e-08 32.2 0.1 6.5 1 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP88969.1 - 1e-17 62.4 7.1 0.006 17.0 0.0 7.1 7 0 0 7 7 6 5 Ankyrin repeat Ank PF00023.30 GAP88969.1 - 2.7e-15 56.0 12.7 0.082 13.4 0.1 7.0 6 0 0 6 6 6 5 Ankyrin repeat CorA PF01544.18 GAP88969.1 - 0.0046 16.3 5.2 0.02 14.2 3.0 2.8 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Rx_N PF18052.1 GAP88969.1 - 0.024 14.9 0.1 0.42 10.9 0.0 2.7 2 0 0 2 2 2 0 Rx N-terminal domain RTP1_C1 PF10363.9 GAP88969.1 - 0.046 13.9 0.3 7.5 6.8 0.0 2.8 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 CHD5 PF04420.14 GAP88969.1 - 0.1 12.5 0.3 0.35 10.7 0.1 1.9 2 0 0 2 2 2 0 CHD5-like protein Tht1 PF04163.12 GAP88969.1 - 0.14 10.9 0.3 0.23 10.2 0.3 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF2721 PF11026.8 GAP88969.1 - 0.17 11.8 2.3 0.17 11.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Bromodomain PF00439.25 GAP88971.1 - 1.7e-08 34.4 0.0 1.7e-07 31.2 0.0 2.4 2 1 0 2 2 2 1 Bromodomain SlyX PF04102.12 GAP88972.1 - 0.0013 19.3 5.4 0.0028 18.2 5.4 1.7 1 1 0 1 1 1 1 SlyX XhlA PF10779.9 GAP88972.1 - 0.0087 16.2 1.5 0.014 15.6 1.5 1.2 1 0 0 1 1 1 1 Haemolysin XhlA SKA1 PF07160.12 GAP88972.1 - 0.011 15.5 2.5 0.014 15.3 2.5 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Sugarporin_N PF11471.8 GAP88972.1 - 0.013 15.5 0.4 0.023 14.7 0.4 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF16 PF01519.16 GAP88972.1 - 0.026 15.0 0.7 0.038 14.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Spc7 PF08317.11 GAP88972.1 - 0.03 13.2 1.7 0.035 13.0 1.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Spc19 PF08287.11 GAP88972.1 - 0.031 14.2 4.4 0.029 14.3 3.3 1.5 2 0 0 2 2 2 0 Spc19 Allexi_40kDa PF05549.11 GAP88972.1 - 0.033 13.7 1.4 0.038 13.5 1.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein ATG16 PF08614.11 GAP88972.1 - 0.036 14.3 4.9 0.036 14.3 4.9 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 GAP88972.1 - 0.043 14.2 1.0 0.043 14.2 1.0 1.7 2 0 0 2 2 1 0 Csm1 N-terminal domain HCMV_UL139 PF12507.8 GAP88972.1 - 0.054 13.9 0.1 0.072 13.5 0.1 1.2 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF4407 PF14362.6 GAP88972.1 - 0.089 12.1 1.9 0.1 11.9 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 GAP88972.1 - 0.092 13.0 1.2 0.14 12.4 1.2 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Herpes_UL6 PF01763.16 GAP88972.1 - 0.12 10.9 1.5 0.17 10.4 1.3 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like OmpH PF03938.14 GAP88972.1 - 0.21 11.9 4.8 0.28 11.5 4.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.19 GAP88972.1 - 0.26 9.2 0.7 0.29 9.0 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ABC_tran_CTD PF16326.5 GAP88972.1 - 0.28 11.5 5.5 0.3 11.4 3.8 1.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain V-SNARE PF05008.15 GAP88972.1 - 0.29 11.5 3.7 0.29 11.5 2.6 1.6 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus ATP11 PF06644.11 GAP88972.1 - 0.33 10.7 4.5 0.42 10.4 4.5 1.1 1 0 0 1 1 1 0 ATP11 protein DUF4349 PF14257.6 GAP88972.1 - 0.35 10.3 5.4 1.1 8.7 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) FAM76 PF16046.5 GAP88972.1 - 0.5 9.7 3.1 0.56 9.5 2.4 1.4 1 1 1 2 2 2 0 FAM76 protein CCDC53 PF10152.9 GAP88972.1 - 0.51 10.7 5.2 0.63 10.5 5.2 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Asp PF00026.23 GAP88973.1 - 3.8e-53 180.9 0.3 4.5e-53 180.7 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP88973.1 - 1.2e-09 38.7 1.0 8.2e-06 26.2 0.1 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal HSP70 PF00012.20 GAP88974.1 - 1.5e-55 188.6 2.0 7e-53 179.7 0.0 3.1 3 1 1 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.13 GAP88974.1 - 0.0013 17.7 0.0 0.0029 16.5 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein CCDC24 PF15669.5 GAP88974.1 - 0.15 12.0 6.3 0.55 10.1 0.5 3.4 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 24 family Syntaxin-6_N PF09177.11 GAP88974.1 - 8.9 6.9 13.0 0.33 11.5 2.1 3.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal adh_short_C2 PF13561.6 GAP88975.1 - 8e-44 149.9 0.0 9.3e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP88975.1 - 3.4e-43 147.4 0.1 4.5e-43 147.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP88975.1 - 3e-10 40.3 0.2 4.4e-10 39.8 0.2 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 GAP88975.1 - 0.00088 18.8 0.2 0.0018 17.8 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAP88975.1 - 0.0037 16.8 0.1 0.016 14.7 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP88975.1 - 0.0043 17.0 0.0 0.0079 16.1 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Acetyltransf_10 PF13673.7 GAP88976.1 - 5e-06 26.5 0.0 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP88976.1 - 0.017 15.5 0.0 0.06 13.8 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 GAP88976.1 - 0.032 14.9 0.1 0.19 12.5 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP88976.1 - 0.068 13.4 0.0 0.5 10.6 0.0 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Ribosomal_S7 PF00177.21 GAP88977.1 - 1.5e-37 128.5 1.8 2e-37 128.1 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Cyt-b5 PF00173.28 GAP88978.1 - 7.5e-10 38.8 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3682 PF12446.8 GAP88978.1 - 0.0031 18.0 8.2 0.0047 17.4 8.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) DUF4407 PF14362.6 GAP88978.1 - 0.12 11.8 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cu_bind_like PF02298.17 GAP88979.1 - 0.047 13.7 0.5 0.17 11.9 0.5 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Copper-bind PF00127.20 GAP88979.1 - 0.089 13.2 0.3 0.2 12.1 0.3 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family CENP-X PF09415.10 GAP88980.1 - 1.1e-24 86.6 0.1 1.8e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 GAP88980.1 - 0.025 14.9 0.1 0.041 14.2 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cwf_Cwc_15 PF04889.12 GAP88980.1 - 0.084 12.6 4.7 0.098 12.4 4.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HK97-gp10_like PF04883.12 GAP88980.1 - 0.12 13.3 0.0 0.22 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Mito_carr PF00153.27 GAP88981.1 - 3e-66 219.4 4.5 1.7e-23 82.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 GAP88981.1 - 0.099 12.4 0.9 0.34 10.7 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Ribosomal_S25 PF03297.15 GAP88982.1 - 1.4e-38 131.1 5.2 1.5e-38 131.0 5.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 GAP88982.1 - 0.009 15.6 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding RNA_pol_Rpc34 PF05158.12 GAP88982.1 - 0.011 15.2 0.4 0.017 14.5 0.1 1.4 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit MarR_2 PF12802.7 GAP88982.1 - 0.04 13.8 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 MarR family F-box-like PF12937.7 GAP88983.1 - 0.011 15.7 0.4 0.031 14.2 0.4 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 GAP88983.1 - 0.06 13.2 0.4 0.16 11.9 0.4 1.8 1 0 0 1 1 1 0 F-box domain Ribosomal_L26 PF16906.5 GAP88987.1 - 2.2e-39 133.8 3.3 3.3e-39 133.2 3.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 GAP88987.1 - 2.9e-08 33.4 0.4 7e-08 32.2 0.4 1.6 1 0 0 1 1 1 1 KOW motif Coa1 PF08695.10 GAP88988.1 - 1.5e-33 115.1 0.0 1.9e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.22 GAP88989.1 - 3.8e-12 45.9 6.7 1.6e-10 40.6 2.6 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 NFACT-R_1 PF05670.13 GAP88990.1 - 4.7e-35 120.5 0.3 2.3e-24 86.1 0.0 2.3 1 1 1 2 2 2 2 NFACT protein RNA binding domain PITH PF06201.13 GAP88991.1 - 3.2e-35 121.6 4.2 9.6e-35 120.0 4.2 1.9 1 1 0 1 1 1 1 PITH domain Rrn6 PF10214.9 GAP88992.1 - 4.6e-100 336.4 0.0 6.9e-100 335.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 GAP88993.1 - 4.6e-25 87.6 0.0 8.6e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Striatin PF08232.12 GAP88993.1 - 0.022 15.4 4.9 0.038 14.6 4.9 1.4 1 0 0 1 1 1 0 Striatin family Troponin PF00992.20 GAP88993.1 - 0.028 14.7 5.3 0.072 13.4 5.3 1.7 1 0 0 1 1 1 0 Troponin zinc_ribbon_6 PF14599.6 GAP88994.1 - 4.2e-24 84.3 0.3 4.2e-24 84.3 0.3 4.2 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 GAP88994.1 - 3.5e-20 72.3 19.4 3.5e-20 72.3 19.4 3.3 3 0 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 GAP88994.1 - 8.3e-08 32.5 9.4 8.3e-08 32.5 9.4 5.4 2 2 4 6 6 6 1 Ring finger domain zf-RING_UBOX PF13445.6 GAP88994.1 - 3.9e-07 30.0 6.5 3.9e-07 30.0 6.5 4.0 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 GAP88994.1 - 3.8e-06 26.7 7.6 3.8e-06 26.7 7.6 6.1 3 2 2 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 GAP88994.1 - 0.00042 20.1 9.3 0.00042 20.1 9.3 4.9 5 2 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 GAP88994.1 - 0.00043 20.5 2.1 0.00043 20.5 2.1 4.3 3 1 1 4 4 4 1 RING-H2 zinc finger domain Mito_carr PF00153.27 GAP88996.1 - 1.3e-41 140.4 8.8 1.5e-15 56.9 0.4 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Mob1_phocein PF03637.17 GAP88997.1 - 7e-70 234.4 0.0 9.5e-70 234.0 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family TPR_15 PF13429.6 GAP88998.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat LSM PF01423.22 GAP89000.1 - 9.5e-14 50.8 0.0 1.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 LSM domain RIFIN PF02009.16 GAP89001.1 - 0.022 14.7 6.2 0.054 13.4 6.2 1.6 1 1 0 1 1 1 0 Rifin Leu_zip PF15294.6 GAP89001.1 - 0.062 12.8 5.5 0.11 12.0 5.5 1.3 1 0 0 1 1 1 0 Leucine zipper Apolipoprotein PF01442.18 GAP89001.1 - 0.33 10.8 12.1 0.56 10.1 12.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoO PF09769.9 GAP89001.1 - 1.8 8.6 5.4 3.5 7.6 4.6 2.0 1 1 0 1 1 1 0 Apolipoprotein O Syntaxin PF00804.25 GAP89001.1 - 2 8.0 10.4 2.5 7.7 9.1 1.7 1 1 1 2 2 2 0 Syntaxin DUF3584 PF12128.8 GAP89001.1 - 3 5.2 13.4 4 4.8 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 GAP89001.1 - 3.5 7.7 6.2 8.3 6.5 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Nup88 PF10168.9 GAP89001.1 - 3.5 5.3 6.9 4.7 4.9 6.9 1.1 1 0 0 1 1 1 0 Nuclear pore component COG2 PF06148.11 GAP89001.1 - 4.7 7.3 8.4 3.3 7.8 3.5 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.6 GAP89001.1 - 7.5 5.1 9.0 11 4.5 9.0 1.1 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 GAP89001.1 - 8.1 5.6 5.3 12 5.0 5.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein NUDIX PF00293.28 GAP89002.1 - 8e-14 51.8 1.2 1e-13 51.5 1.2 1.0 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.15 GAP89003.1 - 1.8e-46 158.1 0.8 3.9e-46 157.0 0.1 1.8 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 GAP89003.1 - 3.7e-19 68.9 1.4 1.2e-18 67.3 0.9 1.9 1 1 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus adh_short PF00106.25 GAP89004.1 - 4.3e-22 78.5 0.1 7.9e-18 64.6 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP89004.1 - 1.2e-12 47.9 0.1 3.2e-09 36.7 0.0 2.5 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP89004.1 - 3.1e-08 33.7 0.6 7.6e-08 32.5 0.2 1.7 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 GAP89004.1 - 0.0095 15.9 0.2 0.023 14.6 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 GAP89004.1 - 0.0096 16.0 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 GAP89004.1 - 0.011 16.4 0.7 0.048 14.3 0.1 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 GAP89004.1 - 0.072 12.5 0.3 0.48 9.8 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RNase_PH PF01138.21 GAP89005.1 - 1e-12 48.7 8.2 9.3e-12 45.6 4.6 2.7 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 GAP89005.1 - 0.068 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Dicty_REP PF05086.12 GAP89005.1 - 0.14 10.1 7.7 1.2 7.0 0.4 2.0 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein AJAP1_PANP_C PF15298.6 GAP89005.1 - 0.62 10.2 12.4 1.1 9.4 2.4 2.2 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Cytochrom_C PF00034.21 GAP89007.1 - 3.1e-12 47.5 0.0 3.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 GAP89007.1 - 3e-09 37.1 0.8 1.2e-08 35.2 0.8 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 GAP89007.1 - 0.00025 20.8 1.3 0.00054 19.7 1.2 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 GAP89007.1 - 0.055 13.0 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 AAA PF00004.29 GAP89009.1 - 5e-91 302.0 0.0 9.6e-49 165.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAP89009.1 - 1.3e-17 63.3 5.9 4.3e-09 36.0 0.1 3.6 4 0 0 4 4 3 2 AAA+ lid domain AAA_2 PF07724.14 GAP89009.1 - 2.9e-12 47.0 0.0 8.3e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAP89009.1 - 3.3e-12 46.5 0.0 6.1e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAP89009.1 - 3.5e-12 46.8 0.7 0.00027 21.2 0.2 4.2 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 GAP89009.1 - 6.5e-11 42.6 0.0 8.1e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAP89009.1 - 1.1e-10 42.1 5.3 0.00085 19.7 0.0 4.6 4 2 1 5 5 3 2 AAA ATPase domain AAA_5 PF07728.14 GAP89009.1 - 9e-10 38.7 0.1 0.0016 18.5 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAP89009.1 - 1.6e-08 34.6 0.0 0.0018 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAP89009.1 - 3.7e-08 33.2 6.0 0.057 13.0 0.0 4.7 4 1 0 5 5 5 3 AAA domain Mg_chelatase PF01078.21 GAP89009.1 - 1.6e-07 30.9 0.3 0.02 14.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 GAP89009.1 - 5.2e-07 29.6 0.0 0.028 14.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 GAP89009.1 - 6.4e-07 30.0 0.0 0.089 13.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 GAP89009.1 - 1.9e-06 27.9 0.0 0.03 14.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 GAP89009.1 - 1.9e-06 28.2 0.0 0.089 13.2 0.0 2.8 2 1 0 2 2 2 2 RNA helicase TIP49 PF06068.13 GAP89009.1 - 2e-06 27.3 0.2 0.051 12.8 0.1 2.5 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_7 PF12775.7 GAP89009.1 - 4.4e-06 26.3 0.0 0.053 13.0 0.0 2.9 2 2 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 GAP89009.1 - 5.2e-06 26.5 0.1 0.072 13.0 0.1 3.2 3 0 0 3 3 3 2 NACHT domain AAA_28 PF13521.6 GAP89009.1 - 7.1e-06 26.4 0.0 0.21 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 GAP89009.1 - 7.2e-06 25.5 0.1 0.085 12.2 0.0 3.2 3 0 0 3 3 3 2 KaiC Cytidylate_kin2 PF13189.6 GAP89009.1 - 7.6e-06 26.2 0.0 0.0047 17.1 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family Rad17 PF03215.15 GAP89009.1 - 1.4e-05 25.1 0.0 0.093 12.6 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_3 PF07726.11 GAP89009.1 - 4.1e-05 23.4 0.0 0.083 12.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 GAP89009.1 - 6e-05 22.9 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 GAP89009.1 - 6.7e-05 23.4 0.0 0.35 11.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 GAP89009.1 - 8.5e-05 22.3 0.1 0.32 10.7 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_11 PF13086.6 GAP89009.1 - 9.8e-05 22.3 0.8 0.37 10.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 GAP89009.1 - 0.00015 21.5 0.0 0.61 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 GAP89009.1 - 0.00017 21.6 0.1 1.5 8.7 0.0 3.3 2 2 0 3 3 3 2 ATPase domain predominantly from Archaea DUF815 PF05673.13 GAP89009.1 - 0.00023 20.4 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TniB PF05621.11 GAP89009.1 - 0.00023 20.6 0.2 0.67 9.3 0.0 3.8 3 1 1 4 4 3 1 Bacterial TniB protein NB-ARC PF00931.22 GAP89009.1 - 0.00031 20.0 0.7 0.64 9.2 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain Zeta_toxin PF06414.12 GAP89009.1 - 0.00036 19.9 0.1 0.19 11.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin PhoH PF02562.16 GAP89009.1 - 0.0004 19.9 0.1 0.52 9.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.6 GAP89009.1 - 0.0022 18.1 0.0 3 8.0 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_17 PF13207.6 GAP89009.1 - 0.0025 18.2 3.3 1.9 8.9 0.1 3.4 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 GAP89009.1 - 0.0028 17.4 0.2 0.42 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAP89009.1 - 0.003 17.9 0.2 0.9 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 GAP89009.1 - 0.0064 16.6 3.1 3 7.9 0.0 3.3 3 0 0 3 3 3 1 Shikimate kinase Parvo_NS1 PF01057.17 GAP89009.1 - 0.011 14.9 0.1 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ResIII PF04851.15 GAP89009.1 - 0.011 15.8 0.0 4.5 7.2 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.16 GAP89009.1 - 0.015 14.2 0.0 1 8.2 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase NTPase_1 PF03266.15 GAP89009.1 - 0.023 14.6 0.6 3.6 7.5 0.0 2.9 3 0 0 3 3 3 0 NTPase DAP3 PF10236.9 GAP89009.1 - 0.029 13.5 0.1 9.6 5.3 0.0 3.3 3 1 1 4 4 3 0 Mitochondrial ribosomal death-associated protein 3 Vps4_C PF09336.10 GAP89009.1 - 0.035 14.1 0.1 7.2 6.7 0.0 3.3 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain MCM PF00493.23 GAP89009.1 - 0.04 13.0 0.0 0.53 9.3 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain Bac_DnaA PF00308.18 GAP89009.1 - 0.055 13.3 0.1 6.1 6.6 0.0 2.9 2 1 0 2 2 2 0 Bacterial dnaA protein Cytidylate_kin PF02224.18 GAP89009.1 - 0.069 12.9 0.2 9.2 5.9 0.1 2.7 2 0 0 2 2 2 0 Cytidylate kinase DUF2075 PF09848.9 GAP89009.1 - 0.079 12.2 0.0 9.9 5.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.9 GAP89009.1 - 0.21 11.3 0.0 9.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 GAP89009.1 - 0.26 10.7 0.8 16 4.9 0.0 2.8 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 GAP89009.1 - 6 7.3 5.5 15 6.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain Snf7 PF03357.21 GAP89010.1 - 5.7e-33 113.9 3.5 6.6e-33 113.7 3.5 1.0 1 0 0 1 1 1 1 Snf7 Sugarporin_N PF11471.8 GAP89010.1 - 0.098 12.6 0.7 0.098 12.6 0.7 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension FUSC PF04632.12 GAP89010.1 - 5.1 5.5 7.5 1.1 7.7 4.0 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF2293 PF10056.9 GAP89011.1 - 1.1e-10 41.6 0.5 1.7e-05 24.9 0.0 2.7 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2293) OSCP PF00213.18 GAP89012.1 - 1.3e-45 155.6 3.6 1.6e-45 155.3 3.6 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glyco_hydro_63 PF03200.16 GAP89013.1 - 1.7e-09 37.0 9.3 2.7e-07 29.7 0.1 4.1 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain RasGEF PF00617.19 GAP89014.1 - 1.1e-44 152.8 0.2 2.1e-44 151.9 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAP89014.1 - 1.4e-12 47.7 0.0 5.8e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 GAP89014.1 - 0.00028 20.5 0.0 0.002 17.7 0.0 2.3 3 0 0 3 3 3 1 Ras family ABC_tran PF00005.27 GAP89014.1 - 0.032 14.7 0.4 0.82 10.2 0.0 3.0 3 1 0 3 3 3 0 ABC transporter AAA_21 PF13304.6 GAP89014.1 - 0.065 13.0 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Pkinase PF00069.25 GAP89015.1 - 1.7e-15 57.1 0.0 2.4e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89015.1 - 1.1e-08 34.7 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP89015.1 - 1.1e-06 28.1 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP89015.1 - 2.7e-05 24.2 0.0 4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP89015.1 - 0.0015 18.1 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 GAP89015.1 - 0.0046 16.3 0.0 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 GAP89015.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 GAP89015.1 - 0.16 10.7 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 GAP89016.1 - 1.5e-11 44.7 0.0 3.4e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GAP89016.1 - 1.5e-05 24.1 0.0 5.1e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 GAP89016.1 - 0.00037 19.9 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 GAP89016.1 - 0.043 13.4 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 GAP89017.1 - 3.5e-08 33.1 0.0 1.6e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89017.1 - 7.9e-05 22.1 0.0 0.0003 20.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF726 PF05277.12 GAP89019.1 - 6.2e-107 357.5 0.0 1e-106 356.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glu-tRNAGln PF02686.15 GAP89020.1 - 1.2e-06 28.7 0.0 3.3e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit TFIIA PF03153.13 GAP89020.1 - 0.085 12.8 11.9 0.13 12.2 11.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA PF00004.29 GAP89021.1 - 7.7e-10 39.3 0.0 1.7e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2203 PF09969.9 GAP89021.1 - 0.0076 17.0 0.1 0.063 14.0 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2203) IGR PF09597.10 GAP89021.1 - 0.013 15.6 0.2 0.046 13.8 0.0 1.9 2 0 0 2 2 2 0 IGR protein motif DNase_NucA_NucB PF14040.6 GAP89022.1 - 0.11 12.9 0.0 2.8 8.3 0.0 2.5 3 0 0 3 3 3 0 Deoxyribonuclease NucA/NucB SNAP PF14938.6 GAP89023.1 - 3.1e-110 368.1 11.8 3.5e-110 367.9 11.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 GAP89023.1 - 6.7e-07 29.5 9.1 0.004 17.4 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAP89023.1 - 0.0005 20.0 14.3 0.43 10.8 0.5 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP89023.1 - 0.0029 18.1 8.6 16 6.4 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP89023.1 - 0.0029 17.3 11.6 0.36 10.7 0.3 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP89023.1 - 0.014 15.5 9.2 5.7 7.4 0.1 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat SMBP PF16785.5 GAP89023.1 - 0.14 12.4 3.4 0.21 11.8 0.3 2.4 2 1 0 2 2 2 0 Small metal-binding protein TPR_16 PF13432.6 GAP89023.1 - 0.62 10.8 14.4 29 5.4 1.8 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAP89023.1 - 0.67 10.1 9.5 11 6.3 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat NUC173 PF08161.12 GAP89024.1 - 3.3e-79 265.3 0.1 1.4e-74 250.2 0.0 4.1 5 0 0 5 5 5 2 NUC173 domain Vac14_Fab1_bd PF12755.7 GAP89024.1 - 0.0094 16.5 0.1 16 6.1 0.0 3.9 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Unpaired PF15972.5 GAP89024.1 - 0.018 14.6 0.4 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 Unpaired protein HEAT PF02985.22 GAP89024.1 - 0.09 13.1 2.1 7.4 7.1 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat V-SNARE PF05008.15 GAP89025.1 - 2e-22 79.3 2.9 2e-22 79.3 2.9 1.7 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 GAP89025.1 - 9.1e-18 64.3 1.7 9.1e-18 64.3 1.7 2.2 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 GAP89025.1 - 0.0017 18.2 0.1 0.0045 16.9 0.1 1.7 1 0 0 1 1 1 1 Sec20 Synaptobrevin PF00957.21 GAP89025.1 - 0.066 13.0 0.5 0.066 13.0 0.5 2.5 2 1 0 3 3 3 0 Synaptobrevin PepX_C PF08530.10 GAP89025.1 - 0.11 12.5 1.1 6 6.7 0.2 2.0 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain SNARE PF05739.19 GAP89025.1 - 0.13 12.3 0.4 0.13 12.3 0.4 3.0 4 0 0 4 4 4 0 SNARE domain Fusion_gly PF00523.18 GAP89025.1 - 0.13 10.4 0.3 0.33 9.2 0.0 1.7 2 0 0 2 2 2 0 Fusion glycoprotein F0 Use1 PF09753.9 GAP89025.1 - 2.6 7.7 9.6 79 2.8 9.6 2.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 CENP-H PF05837.12 GAP89025.1 - 4.4 7.7 6.8 1.5 9.3 1.9 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Glyco_hydro_cc PF11790.8 GAP89026.1 - 5.8e-27 94.8 0.0 7.1e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Amino_oxidase PF01593.24 GAP89027.1 - 5.7e-21 75.3 0.1 2.1e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAP89027.1 - 6.6e-12 45.5 0.1 1.6e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP89027.1 - 2.2e-05 23.9 0.1 0.00052 19.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP89027.1 - 0.00011 21.9 0.0 0.001 18.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAP89027.1 - 0.00042 20.3 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 GAP89027.1 - 0.00091 18.7 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAP89027.1 - 0.0012 17.6 0.1 0.031 13.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 GAP89027.1 - 0.011 14.9 0.2 0.021 14.0 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAP89027.1 - 0.025 13.9 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP89027.1 - 0.13 11.3 0.2 0.22 10.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAP89027.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 GAP89027.1 - 0.17 12.4 0.0 0.37 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CtaG_Cox11 PF04442.14 GAP89028.1 - 7.9e-59 198.0 0.0 1.4e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 HAD_2 PF13419.6 GAP89030.1 - 1.6e-07 31.6 0.0 2.2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP89030.1 - 0.00074 19.5 0.1 0.0013 18.7 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3433 PF11915.8 GAP89032.1 - 1.7e-07 31.6 4.1 1.7e-07 31.6 4.1 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3433) COX2_TM PF02790.15 GAP89032.1 - 0.075 13.2 1.0 2.3 8.5 0.0 2.8 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF647 PF04884.14 GAP89034.1 - 3.1e-99 331.5 2.1 3.8e-99 331.2 2.1 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Cyto_heme_lyase PF01265.17 GAP89035.1 - 6.3e-41 140.9 10.8 3.1e-38 132.0 0.2 3.6 2 2 0 2 2 2 2 Cytochrome c/c1 heme lyase SPX PF03105.19 GAP89035.1 - 4.7 7.0 4.7 7 6.5 4.7 1.2 1 0 0 1 1 1 0 SPX domain Cytomega_gL PF01801.16 GAP89036.1 - 0.16 11.3 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L MDD_C PF18376.1 GAP89037.1 - 5.6e-63 212.1 0.1 7.7e-63 211.6 0.1 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 GAP89037.1 - 9e-09 35.5 1.6 9e-09 35.5 1.6 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain MFS_1 PF07690.16 GAP89038.1 - 8.9e-25 87.3 31.3 8.9e-25 87.3 31.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP89038.1 - 2.4e-11 43.2 28.5 1.2e-10 40.8 28.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter NACHT PF05729.12 GAP89039.1 - 3.3e-06 27.1 0.0 1.1e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP89039.1 - 5.3e-05 23.7 0.0 0.00033 21.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Helo_like_N PF17111.5 GAP89039.1 - 0.00068 19.1 1.5 0.0012 18.3 0.8 1.7 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 GAP89039.1 - 0.01 16.1 0.0 0.063 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAP89039.1 - 0.014 15.9 0.0 0.14 12.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF948 PF06103.11 GAP89039.1 - 0.11 12.7 1.8 8.1 6.8 0.2 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3071 PF11268.8 GAP89040.1 - 0.14 12.2 0.7 0.23 11.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) Mannitol_dh_C PF08125.13 GAP89044.1 - 2e-41 142.1 0.1 3e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 GAP89044.1 - 7e-21 75.0 0.2 1.8e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UPF0052 PF01933.18 GAP89044.1 - 0.088 12.0 0.3 0.17 11.1 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Coatomer_WDAD PF04053.14 GAP89045.1 - 3.9e-167 556.8 0.0 1.5e-166 554.9 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 GAP89045.1 - 3.3e-38 129.0 7.8 1.6e-05 25.6 0.0 8.9 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP89045.1 - 9.1e-07 29.1 0.2 4.8 7.6 0.0 6.2 4 3 2 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP89045.1 - 5.3e-06 25.4 2.2 0.032 12.9 0.0 4.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 GAP89045.1 - 0.0096 15.9 0.1 5 7.2 0.0 3.9 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region CobT PF06213.12 GAP89045.1 - 0.34 10.3 12.7 0.48 9.8 12.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_3_Rpc31 PF11705.8 GAP89045.1 - 0.68 10.2 22.6 1 9.6 22.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 GAP89045.1 - 1.2 9.1 11.1 1.5 8.7 11.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 GAP89045.1 - 2 7.7 19.3 2.8 7.2 19.3 1.2 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 GAP89045.1 - 3.9 6.7 14.1 5.1 6.3 14.1 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 GAP89045.1 - 7.3 4.7 20.7 9.2 4.3 20.7 1.1 1 0 0 1 1 1 0 Nop14-like family Pyrid_ox_like PF16242.5 GAP89047.1 - 3.1e-26 91.7 0.0 4.6e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 GAP89047.1 - 5.9e-11 42.4 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TP_methylase PF00590.20 GAP89048.1 - 1.1e-13 51.7 0.0 1.9e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.8 GAP89049.1 - 2.2e-07 31.0 0.1 3.8e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP89049.1 - 6.8e-05 23.1 0.3 0.00013 22.3 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 GAP89049.1 - 0.00026 21.0 0.7 0.00064 19.7 0.7 1.7 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins PDDEXK_1 PF12705.7 GAP89049.1 - 0.0071 16.3 6.0 0.0071 16.3 6.0 1.5 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily zf-C2H2 PF00096.26 GAP89049.1 - 0.038 14.4 0.5 0.37 11.3 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Vfa1 PF08432.10 GAP89049.1 - 3.6 7.9 12.8 0.77 10.1 6.2 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 UQ_con PF00179.26 GAP89050.1 - 3.1e-35 120.9 0.0 3.5e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAP89050.1 - 0.0018 18.0 0.2 0.0037 17.0 0.2 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAP89050.1 - 0.23 11.7 1.0 0.34 11.2 0.5 1.5 1 1 0 1 1 1 0 RWD domain Glyco_trans_1_4 PF13692.6 GAP89051.1 - 9e-09 35.9 0.0 3.1e-08 34.1 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 GAP89051.1 - 1.7e-05 24.5 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 GAP89051.1 - 0.016 15.6 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF2484 PF10658.9 GAP89051.1 - 0.82 10.0 4.4 5.4 7.4 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) SR-25 PF10500.9 GAP89051.1 - 1.3 8.6 3.3 1.9 8.0 3.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Serglycin PF04360.12 GAP89051.1 - 1.3 8.9 4.6 2.2 8.2 4.6 1.2 1 0 0 1 1 1 0 Serglycin CTP_synth_N PF06418.14 GAP89052.1 - 3.4e-117 390.5 0.1 4.5e-117 390.1 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 GAP89052.1 - 9.8e-51 172.2 0.0 1.7e-50 171.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 GAP89052.1 - 0.00072 19.4 0.2 0.0061 16.3 0.2 2.2 1 1 0 1 1 1 1 Peptidase C26 Cation_efflux PF01545.21 GAP89053.1 - 1.3e-50 171.9 2.3 1.8e-50 171.5 2.3 1.2 1 0 0 1 1 1 1 Cation efflux family Mito_carr PF00153.27 GAP89054.1 - 1.3e-55 185.3 3.9 1.7e-18 66.3 0.2 3.5 4 0 0 4 4 4 3 Mitochondrial carrier protein His_Phos_1 PF00300.22 GAP89055.1 - 8.2e-06 25.6 2.9 3.7 7.2 0.1 4.7 4 1 1 5 5 5 4 Histidine phosphatase superfamily (branch 1) YokU PF14122.6 GAP89055.1 - 0.21 11.6 0.0 0.38 10.8 0.0 1.3 1 0 0 1 1 1 0 YokU-like protein, putative antitoxin DUF3433 PF11915.8 GAP89056.1 - 1.3e-28 99.3 9.1 3.6e-17 62.6 0.4 4.1 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Peptidase_C13 PF01650.18 GAP89057.1 - 3.8e-40 138.0 0.2 4.9e-40 137.7 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.7 GAP89058.1 - 5.7e-14 52.5 0.3 2.3e-12 47.2 0.3 2.3 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Cwf_Cwc_15 PF04889.12 GAP89058.1 - 0.72 9.5 6.0 1 9.0 6.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 GAP89058.1 - 3.9 5.5 10.2 5 5.1 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi LysM PF01476.20 GAP89060.1 - 1.9e-10 40.6 0.0 0.00021 21.3 0.0 2.2 2 0 0 2 2 2 2 LysM domain Gp138_N PF18352.1 GAP89060.1 - 0.15 12.1 0.0 11 6.2 0.0 2.2 2 0 0 2 2 2 0 Phage protein Gp138 N-terminal domain CorA PF01544.18 GAP89061.1 - 0.028 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CZB PF13682.6 GAP89061.1 - 0.04 14.3 0.0 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 Chemoreceptor zinc-binding domain CoA_binding_3 PF13727.6 GAP89061.1 - 0.05 13.6 0.3 0.1 12.6 0.3 1.4 1 0 0 1 1 1 0 CoA-binding domain DUF892 PF05974.12 GAP89062.1 - 0.055 13.5 0.1 0.093 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Glycogen_syn PF05693.13 GAP89063.1 - 0 1158.9 0.0 0 1158.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 GAP89063.1 - 8.1e-06 25.5 0.0 0.0031 17.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 GAP89063.1 - 2.4e-05 24.8 0.0 0.021 15.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 GAP89063.1 - 2.8e-05 24.2 0.3 8.6e-05 22.6 0.2 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 GAP89063.1 - 0.00073 20.0 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain F-box-like PF12937.7 GAP89064.1 - 1.7e-06 27.8 0.4 4.8e-06 26.4 0.4 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 GAP89064.1 - 0.0064 16.3 5.5 0.057 13.3 4.1 2.8 2 1 0 2 2 2 1 F-box domain cobW PF02492.19 GAP89065.1 - 7.2e-38 129.9 0.0 9.7e-38 129.5 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 GAP89065.1 - 0.00054 19.9 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF463 PF04317.12 GAP89065.1 - 0.012 14.6 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Viral_helicase1 PF01443.18 GAP89065.1 - 0.03 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 GAP89065.1 - 0.095 12.5 0.1 0.74 9.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GAP89065.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Indigoidine_A PF04227.12 GAP89066.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Indigoidine synthase A like protein BBE PF08031.12 GAP89067.1 - 1.6e-05 24.9 0.1 3.1e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF1754 PF08555.10 GAP89069.1 - 6.2e-07 30.1 8.8 6.5e-07 30.1 8.8 1.0 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Lin-8 PF03353.15 GAP89070.1 - 6.4 6.3 7.2 8.7 5.8 7.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Fungal_trans PF04082.18 GAP89072.1 - 7.1e-17 61.3 0.0 1.3e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP89072.1 - 0.00016 21.7 10.1 0.00016 21.7 10.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAP89073.1 - 2.8e-40 138.3 49.5 2.8e-40 138.3 49.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP89073.1 - 1.1e-11 43.9 17.8 1.5e-11 43.4 17.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mx_ML PF17536.2 GAP89075.1 - 0.0074 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Matrix and Matrix long proteins N-terminal Apc13p PF05839.11 GAP89076.1 - 8.5e-33 112.4 0.1 1e-32 112.1 0.1 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.16 GAP89077.1 - 2.4e-38 131.1 0.0 2.8e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CRAL_TRIO PF00650.20 GAP89078.1 - 8.3e-41 139.4 0.0 1.3e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAP89078.1 - 4.5e-14 52.4 2.4 7.8e-14 51.6 2.4 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAP89078.1 - 0.0048 17.1 0.0 0.0076 16.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.10 GAP89080.1 - 3.5e-82 276.1 0.1 4.6e-82 275.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 GAP89080.1 - 1.7e-39 135.4 0.1 2.5e-39 134.8 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MFAP1 PF06991.11 GAP89081.1 - 3.3e-74 249.4 36.6 3.3e-74 249.4 36.6 2.9 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing Alb1 PF09135.11 GAP89082.1 - 6e-28 97.8 10.0 6e-28 97.8 10.0 1.7 2 0 0 2 2 2 1 Alb1 AAA_15 PF13175.6 GAP89082.1 - 0.068 12.9 0.5 0.072 12.8 0.5 1.1 1 0 0 1 1 1 0 AAA ATPase domain Nop25 PF09805.9 GAP89082.1 - 0.13 12.8 12.7 0.22 12.0 12.7 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF4168 PF13767.6 GAP89082.1 - 1.3 10.3 6.1 2.5 9.3 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) UCH PF00443.29 GAP89083.1 - 5.2e-34 117.9 0.0 1.5e-33 116.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAP89083.1 - 6.2e-05 22.7 0.1 0.00023 20.9 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1957 PF09210.11 GAP89083.1 - 0.15 12.5 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) Abhydrolase_2 PF02230.16 GAP89084.1 - 4.4e-16 59.4 0.0 5.5e-15 55.8 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 GAP89084.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.4 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 GAP89084.1 - 0.072 12.6 0.0 0.31 10.6 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAP89084.1 - 0.21 10.8 0.0 7.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAP89084.1 - 0.23 11.5 0.1 9.5 6.2 0.0 2.4 2 1 0 2 2 2 0 Thioesterase domain Pkinase PF00069.25 GAP89085.1 - 4.3e-23 82.0 0.0 5.6e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89085.1 - 1e-14 54.5 0.0 1.5e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP89085.1 - 3.3e-05 23.3 0.1 7.8e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAP89085.1 - 0.011 14.5 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 GAP89085.1 - 0.04 12.9 0.1 0.058 12.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sec8_exocyst PF04048.14 GAP89086.1 - 4.8e-49 165.9 1.5 1.3e-48 164.6 1.5 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 GAP89086.1 - 4.8e-10 39.2 0.6 8.8e-10 38.3 0.6 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 GAP89086.1 - 0.033 12.8 1.0 0.079 11.5 1.0 1.6 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Anti-adapt_IraP PF10796.9 GAP89086.1 - 0.089 13.4 0.1 0.44 11.1 0.1 2.2 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein SMI1_KNR4 PF09346.10 GAP89088.1 - 3.4e-31 108.4 0.0 6.9e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) UPF0220 PF05255.11 GAP89089.1 - 8.4e-61 204.3 1.3 3.4e-57 192.6 1.5 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0220) AP3D1 PF06375.11 GAP89089.1 - 0.013 15.8 0.6 0.016 15.4 0.6 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Ferlin_C PF16165.5 GAP89089.1 - 0.068 13.1 0.7 0.11 12.4 0.7 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Peptidase_S49_N PF08496.10 GAP89089.1 - 0.69 10.0 3.9 1.2 9.1 3.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3341 PF11821.8 GAP89089.1 - 0.78 9.4 2.8 0.6 9.7 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) DUF5337 PF17272.2 GAP89089.1 - 3.9 7.4 6.3 0.26 11.1 0.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Mito_carr PF00153.27 GAP89090.1 - 1.1e-59 198.3 12.4 3e-19 68.7 0.1 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein DUF3246 PF11596.8 GAP89090.1 - 0.0011 18.4 8.8 0.15 11.4 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3246) Sporozoite_P67 PF05642.11 GAP89090.1 - 0.011 13.9 0.1 0.029 12.5 0.1 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen PD-C2-AF1 PF09310.10 GAP89090.1 - 0.057 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 GCIP PF13324.6 GAP89090.1 - 0.063 12.9 0.1 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 GAP89090.1 - 1.2 9.6 8.9 3.3 8.2 5.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 GAP89090.1 - 1.3 8.7 9.6 1.6 8.4 4.4 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3245 PF11595.8 GAP89090.1 - 3.7 8.0 9.9 13 6.3 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) K_channel_TID PF07941.11 GAP89090.1 - 4.6 7.8 13.2 0.08 13.4 2.5 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain FYDLN_acid PF09538.10 GAP89090.1 - 5.1 7.8 11.2 7.2 7.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RXT2_N PF08595.11 GAP89090.1 - 9.1 6.3 5.3 32 4.5 2.7 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Urm1 PF09138.11 GAP89091.1 - 2e-35 121.0 0.1 2.4e-35 120.8 0.1 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 GAP89091.1 - 0.016 15.8 0.0 0.023 15.3 0.0 1.3 1 0 0 1 1 1 0 ThiS family zf-C2H2 PF00096.26 GAP89092.1 - 4.9e-13 48.7 32.0 0.00012 22.3 0.2 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP89092.1 - 2.7e-06 27.8 29.5 0.05 14.4 1.6 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 GAP89092.1 - 4.4e-06 26.9 8.1 0.00011 22.4 1.0 3.1 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 GAP89092.1 - 6.6e-06 26.3 33.2 0.0029 18.0 1.2 4.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-met PF12874.7 GAP89092.1 - 0.026 14.9 7.7 0.66 10.4 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 GAP89092.1 - 3.7 8.3 8.4 6.2 7.5 0.1 3.7 2 2 1 3 3 3 0 FOXP coiled-coil domain RRM_1 PF00076.22 GAP89093.1 - 3.6e-24 84.4 0.2 7.8e-16 57.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAP89093.1 - 0.063 12.9 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMV_1a_C PF12503.8 GAP89093.1 - 0.064 13.3 0.0 4.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein C terminal MIF4G_like PF09088.11 GAP89094.1 - 2.2e-86 288.5 0.0 3.7e-86 287.8 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 GAP89094.1 - 7.5e-69 232.2 0.0 2.1e-68 230.7 0.0 1.7 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 GAP89094.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 MIF4G domain Pkinase PF00069.25 GAP89095.1 - 2.4e-65 220.5 0.0 2.9e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89095.1 - 3.4e-25 88.8 0.0 4.4e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP89095.1 - 1.8e-06 27.5 0.0 7.6e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAP89095.1 - 0.0016 18.4 0.2 0.007 16.3 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 GAP89095.1 - 0.0048 17.1 0.2 0.0077 16.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) Seadorna_VP7 PF07387.11 GAP89095.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 GAP89095.1 - 0.094 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 GAP89095.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAP89095.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 GAP89096.1 - 2.2e-21 75.7 15.7 0.0037 18.1 0.0 10.8 10 2 1 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP89096.1 - 0.0036 17.6 0.1 8.1 6.8 0.0 4.1 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SPT_ssu-like PF11779.8 GAP89097.1 - 6.3e-22 76.9 2.6 8.4e-22 76.5 2.6 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like RF-1 PF00472.20 GAP89098.1 - 7.6e-25 87.1 0.8 1.1e-24 86.5 0.8 1.2 1 0 0 1 1 1 1 RF-1 domain Actin PF00022.19 GAP89099.1 - 3.5e-151 503.4 0.0 1.3e-150 501.6 0.0 1.7 1 1 0 1 1 1 1 Actin Fes1 PF08609.10 GAP89100.1 - 1e-27 96.8 0.2 1.7e-26 92.9 0.6 2.3 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 GAP89100.1 - 0.0017 18.4 0.1 0.28 11.6 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 GAP89100.1 - 0.12 12.4 2.6 7.5 6.8 0.1 3.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ribosomal_L5_C PF00673.21 GAP89101.1 - 4.9e-26 90.7 0.0 2.1e-25 88.7 0.0 2.0 2 1 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 GAP89101.1 - 7.5e-08 32.6 0.0 2.3e-07 31.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 UCH_1 PF13423.6 GAP89102.1 - 1e-31 110.7 0.0 4.8e-30 105.2 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 GAP89102.1 - 3.4e-16 59.5 0.0 1.2e-15 57.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HA2 PF04408.23 GAP89104.1 - 2.4e-17 63.2 0.4 9e-17 61.3 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAP89104.1 - 6.5e-16 58.5 0.0 3.9e-15 56.0 0.0 2.4 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAP89104.1 - 8.2e-16 58.3 0.0 2e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAP89104.1 - 2.9e-11 43.4 2.0 4.1e-11 43.0 0.8 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.22 GAP89104.1 - 1e-06 29.0 0.2 2.5e-06 27.8 0.2 1.7 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.6 GAP89104.1 - 0.0023 18.2 0.4 0.0086 16.3 0.4 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 GAP89104.1 - 0.0028 17.7 0.1 0.0099 15.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_29 PF13555.6 GAP89104.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IHABP4_N PF16174.5 GAP89104.1 - 0.016 15.8 7.0 0.11 13.2 0.1 2.7 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal ATPase PF06745.13 GAP89104.1 - 0.02 14.2 0.1 0.056 12.8 0.1 1.7 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.12 GAP89104.1 - 0.79 9.0 2.6 11 5.2 0.5 3.2 1 1 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 GAP89104.1 - 0.81 10.1 4.3 0.26 11.8 0.5 2.2 2 1 0 2 2 2 0 AAA domain zf-C2HE PF16278.5 GAP89105.1 - 4.8e-16 59.0 0.0 8.7e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 GAP89105.1 - 6.4e-13 49.3 0.2 2.8e-12 47.2 0.2 1.8 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAP89105.1 - 1.3e-12 48.2 2.9 7.1e-11 42.6 2.9 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AT_hook PF02178.19 GAP89106.1 - 0.00011 21.6 41.7 0.019 14.8 4.3 5.5 5 0 0 5 5 5 4 AT hook motif NOA36 PF06524.12 GAP89106.1 - 2.4 7.4 6.0 3.1 7.0 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein Mucin PF01456.17 GAP89106.1 - 6.2 6.8 14.9 2.9 7.9 2.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Pox_Ag35 PF03286.14 GAP89106.1 - 7.5 6.3 15.1 0.031 14.0 5.9 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.16 GAP89107.1 - 9.2e-10 38.2 0.0 1.1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit PepX_C PF08530.10 GAP89108.1 - 2.8e-44 151.7 0.1 3.8e-44 151.3 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 GAP89108.1 - 8.3e-21 74.8 0.0 4e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 GAP89108.1 - 0.037 13.3 0.0 0.097 11.9 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Sulfatase PF00884.23 GAP89109.1 - 2.4e-65 220.9 0.5 3e-65 220.6 0.5 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 GAP89109.1 - 1.9e-06 27.7 1.3 0.0086 15.7 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 GAP89109.1 - 0.0019 18.4 0.0 0.0042 17.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 GAP89109.1 - 0.032 12.9 0.0 2.5 6.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF229) DUF1501 PF07394.12 GAP89109.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Med5 PF08689.10 GAP89110.1 - 3.1e-99 333.3 0.0 5.2e-98 329.2 0.0 2.5 1 1 1 2 2 2 2 Mediator complex subunit Med5 RPOL_N PF14700.6 GAP89110.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal NRD1_2 PF01995.16 GAP89112.1 - 0.15 11.3 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 HET PF06985.11 GAP89113.1 - 1.2e-10 41.9 8.5 1.5e-08 35.1 1.9 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) SKG6 PF08693.10 GAP89114.1 - 0.036 13.5 0.4 0.07 12.6 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 GAP89114.1 - 0.076 13.9 0.0 0.14 13.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 GAP89114.1 - 0.28 11.1 0.1 0.53 10.2 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain DUF4202 PF13875.6 GAP89115.1 - 3.7e-73 245.4 0.0 4.2e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF5584 PF17822.1 GAP89115.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5584) UPF0181 PF03701.14 GAP89115.1 - 0.15 11.7 0.2 0.31 10.7 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0181) FMN_dh PF01070.18 GAP89116.1 - 3.3e-111 371.7 0.1 1.8e-110 369.2 0.1 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAP89116.1 - 3.8e-17 62.2 0.0 8.1e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 GAP89116.1 - 1.5e-05 24.3 1.2 5.5e-05 22.5 0.1 2.2 2 1 1 3 3 3 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAP89116.1 - 0.00014 21.0 1.1 0.0033 16.5 0.5 2.5 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 GAP89116.1 - 0.0024 17.3 0.1 0.004 16.6 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 GAP89116.1 - 0.018 14.3 0.1 0.36 10.1 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ndc1_Nup PF09531.10 GAP89117.1 - 8.4 5.0 8.4 11 4.5 8.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Heme_oxygenase PF01126.20 GAP89118.1 - 2.9e-15 56.6 0.0 3.7e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Heme oxygenase EthD PF07110.11 GAP89119.1 - 0.0038 18.3 0.0 0.0082 17.3 0.0 1.6 1 0 0 1 1 1 1 EthD domain EamA PF00892.20 GAP89120.1 - 6.9e-06 26.3 12.2 8.2e-06 26.0 12.2 1.1 1 0 0 1 1 1 1 EamA-like transporter family Ras PF00071.22 GAP89121.1 - 9.2e-57 191.2 0.1 1.1e-56 190.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP89121.1 - 8e-32 110.0 0.0 1.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP89121.1 - 2.7e-13 49.7 0.0 3.2e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAP89121.1 - 2.6e-08 33.9 0.0 4.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAP89121.1 - 3.8e-07 29.7 0.0 4.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAP89121.1 - 4.7e-06 26.3 0.0 0.0002 21.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAP89121.1 - 0.00016 21.6 0.1 0.0036 17.2 0.1 2.3 1 1 2 3 3 3 1 RsgA GTPase SRPRB PF09439.10 GAP89121.1 - 0.0023 17.4 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 GAP89121.1 - 0.0028 17.6 0.0 0.0052 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 GAP89121.1 - 0.0049 16.7 0.2 0.15 11.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 GAP89121.1 - 0.0084 15.9 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 GAP89121.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 GAP89121.1 - 0.012 16.1 0.1 0.02 15.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 GAP89121.1 - 0.016 14.5 0.1 0.048 12.9 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 GAP89121.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAP89121.1 - 0.027 14.0 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 GAP89121.1 - 0.056 13.0 0.0 0.13 11.9 0.0 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 GAP89121.1 - 0.065 13.6 0.1 0.32 11.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 GAP89121.1 - 0.07 13.0 0.3 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 GAP89121.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NTPase TniB PF05621.11 GAP89121.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 GAP89121.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 GAP89121.1 - 0.16 11.1 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Borrelia_P83 PF05262.11 GAP89122.1 - 0.086 11.3 1.7 0.11 11.0 1.7 1.3 1 1 0 1 1 1 0 Borrelia P83/100 protein AAA_lid_2 PF17863.1 GAP89123.1 - 0.003 17.3 1.8 0.011 15.5 1.8 2.0 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 GAP89123.1 - 0.0033 17.3 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GDA1_CD39 PF01150.17 GAP89124.1 - 5.9e-99 331.6 0.0 7.7e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PUL PF08324.11 GAP89125.1 - 8e-63 212.3 0.0 1.4e-62 211.4 0.0 1.4 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 GAP89125.1 - 9.1e-35 119.7 0.0 1.8e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 GAP89125.1 - 3.1e-15 56.0 0.0 6.7e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 GAP89125.1 - 1.6e-09 37.9 0.0 2.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 GAP89125.1 - 0.00019 21.8 0.2 0.0018 18.7 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 GAP89125.1 - 0.00063 19.2 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 GAP89125.1 - 0.0035 17.4 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 GAP89125.1 - 0.0082 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family IBN_N PF03810.19 GAP89125.1 - 0.05 13.5 0.2 0.099 12.6 0.2 1.5 1 0 0 1 1 1 0 Importin-beta N-terminal domain Thioredoxin_4 PF13462.6 GAP89125.1 - 0.064 13.4 1.5 0.29 11.3 0.1 2.3 2 1 0 2 2 2 0 Thioredoxin Redoxin PF08534.10 GAP89125.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 GAP89125.1 - 0.16 12.3 0.0 1.7 9.0 0.0 2.3 1 1 0 1 1 1 0 Thioredoxin-like Kinesin PF00225.23 GAP89126.1 - 2.1e-113 378.6 0.0 3.8e-113 377.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAP89126.1 - 2.7e-26 92.3 0.0 7.3e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DUF1087 PF06465.13 GAP89126.1 - 0.03 14.4 0.1 0.03 14.4 0.1 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1087) YabA PF06156.13 GAP89126.1 - 1.3 9.7 10.0 3.4 8.4 0.1 3.3 3 1 0 3 3 3 0 Initiation control protein YabA Cupin_8 PF13621.6 GAP89127.1 - 1.3e-66 224.9 0.0 1.5e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 GAP89127.1 - 1.4e-06 28.0 0.2 0.0013 18.3 0.1 2.4 2 1 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 GAP89127.1 - 0.043 14.2 0.1 1.6 9.2 0.0 2.8 3 0 0 3 3 3 0 JmjC domain, hydroxylase Sterol-sensing PF12349.8 GAP89129.1 - 1.1e-35 122.7 10.6 1.4e-35 122.4 9.5 1.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 GAP89129.1 - 1.7e-09 36.4 5.9 3.9e-09 35.2 5.9 1.5 1 0 0 1 1 1 1 Patched family DUF2244 PF10003.9 GAP89129.1 - 0.038 13.7 6.4 0.12 12.0 0.2 2.7 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) 14-3-3 PF00244.20 GAP89130.1 - 7.7e-06 25.6 0.0 1.9e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 14-3-3 protein WD40 PF00400.32 GAP89131.1 - 8.8e-11 42.2 10.2 0.13 13.2 0.0 5.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP89131.1 - 3e-05 24.2 0.0 17 5.8 0.0 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP89131.1 - 0.0055 15.4 0.0 0.014 14.1 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Spb1_C PF07780.12 GAP89132.1 - 1.4e-80 269.9 39.6 1.4e-80 269.9 39.6 3.4 2 1 0 2 2 2 1 Spb1 C-terminal domain FtsJ PF01728.19 GAP89132.1 - 2.5e-55 187.3 0.0 5.7e-55 186.1 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 GAP89132.1 - 6.9e-48 162.6 7.8 6.9e-48 162.6 7.8 4.9 3 2 1 4 4 4 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 GAP89132.1 - 0.0055 16.5 0.1 0.071 12.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ebp2 PF05890.12 GAP89133.1 - 1.9e-90 303.1 14.0 1.9e-90 303.1 14.0 2.8 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Ank_2 PF12796.7 GAP89134.1 - 1.3e-64 214.7 5.6 2.3e-12 47.3 0.0 7.9 3 2 7 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP89134.1 - 3.5e-40 135.9 1.8 4.5e-08 33.5 0.1 9.2 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP89134.1 - 1.1e-34 114.5 3.2 0.00019 21.6 0.0 12.7 13 0 0 13 13 13 6 Ankyrin repeat Ank PF00023.30 GAP89134.1 - 4e-33 112.4 11.1 0.0028 18.0 0.0 11.3 12 0 0 12 12 10 7 Ankyrin repeat Ank_5 PF13857.6 GAP89134.1 - 7e-32 109.1 7.0 1.2e-06 28.7 0.1 9.7 4 3 5 9 9 9 6 Ankyrin repeats (many copies) Cutinase PF01083.22 GAP89134.1 - 2.7e-06 27.5 0.0 1.2e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 GAP89134.1 - 8.9e-06 26.5 0.0 3e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAP89134.1 - 3.2e-05 23.8 0.1 0.0012 18.6 0.0 2.6 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 GAP89134.1 - 0.00014 21.5 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 GAP89134.1 - 0.00037 19.8 0.0 0.00091 18.6 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 GAP89134.1 - 0.0045 16.2 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 GAP89134.1 - 0.1 12.4 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) DUF2207 PF09972.9 GAP89135.1 - 0.2 10.4 0.4 0.29 9.9 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FtsX PF02687.21 GAP89135.1 - 0.72 10.4 6.8 1.3 9.5 6.8 1.3 1 0 0 1 1 1 0 FtsX-like permease family Hce2 PF14856.6 GAP89136.1 - 1.7e-06 28.3 0.0 2.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Cyanate_lyase PF02560.14 GAP89137.1 - 2.6e-31 107.2 0.0 3.9e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.12 GAP89137.1 - 0.0025 17.5 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_31 PF13560.6 GAP89137.1 - 0.011 16.0 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 GAP89137.1 - 0.021 14.9 0.1 0.033 14.2 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix TetR_N PF00440.23 GAP89137.1 - 0.038 13.8 0.4 0.11 12.3 0.4 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family NAD_kinase PF01513.21 GAP89138.1 - 3.6e-71 239.8 0.0 5.8e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GAP89138.1 - 0.07 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pol_alpha_B_N PF08418.10 GAP89139.1 - 0.085 12.8 2.1 0.13 12.2 0.1 1.9 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal Abhydrolase_1 PF00561.20 GAP89140.1 - 1.9e-17 63.8 0.1 1.4e-06 28.1 0.0 3.3 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 GAP89140.1 - 5.4e-17 61.8 0.0 2.1e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein GTP_EFTU PF00009.27 GAP89141.1 - 5.9e-56 189.1 0.2 7.9e-56 188.7 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAP89141.1 - 1.5e-24 86.5 0.0 3.6e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAP89141.1 - 2.2e-16 60.0 2.6 2.2e-16 60.0 2.6 2.2 2 1 1 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAP89141.1 - 8.6e-05 22.6 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP89141.1 - 0.00059 19.8 0.0 0.0018 18.2 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 GAP89141.1 - 0.0098 15.5 0.3 0.055 13.1 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 GAP89141.1 - 0.039 13.7 0.3 8.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Thioredoxin PF00085.20 GAP89142.1 - 2e-60 201.2 0.0 1e-29 102.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 GAP89142.1 - 2.7e-25 89.1 1.4 7.3e-25 87.7 0.5 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 GAP89142.1 - 1.9e-17 63.7 0.0 5.6e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 GAP89142.1 - 3.7e-12 46.2 0.0 2.2e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GAP89142.1 - 7e-09 35.9 0.0 0.023 15.0 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 GAP89142.1 - 6.4e-08 32.7 0.0 0.0033 17.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 GAP89142.1 - 4.1e-07 29.9 0.1 0.0044 16.9 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family HyaE PF07449.11 GAP89142.1 - 3.3e-06 27.0 0.0 0.011 15.7 0.0 3.3 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 GAP89142.1 - 8.6e-06 25.5 0.0 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 GAP89142.1 - 4.8e-05 23.1 0.3 0.038 13.7 0.0 2.3 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.13 GAP89142.1 - 7.6e-05 22.9 0.1 0.076 13.2 0.0 2.7 2 1 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_6 PF13848.6 GAP89142.1 - 7.9e-05 22.6 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.6 GAP89142.1 - 0.00028 21.1 1.0 0.82 9.8 0.0 3.4 3 2 1 4 4 4 2 Thioredoxin TraF PF13728.6 GAP89142.1 - 0.001 19.0 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Glutaredoxin PF00462.24 GAP89142.1 - 0.0015 18.7 0.1 1.8 8.8 0.0 3.0 2 1 0 2 2 2 2 Glutaredoxin Thioredoxin_3 PF13192.6 GAP89142.1 - 0.0031 17.5 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin domain zf-rbx1 PF12678.7 GAP89143.1 - 3.7e-10 39.9 0.5 7e-10 39.1 0.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 GAP89143.1 - 5.4e-08 33.0 1.9 5.4e-08 33.0 1.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 GAP89143.1 - 5.7e-07 29.3 0.3 9.6e-07 28.6 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP89143.1 - 2.5e-06 27.4 0.3 5.1e-05 23.2 0.0 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 GAP89143.1 - 3e-06 27.0 4.8 2.1e-05 24.3 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP89143.1 - 3.3e-06 27.0 1.4 7.8e-06 25.8 1.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAP89143.1 - 0.00013 21.7 2.5 0.00031 20.5 2.5 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAP89143.1 - 0.0013 18.5 1.6 0.0013 18.5 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 GAP89143.1 - 0.0036 16.9 1.0 0.0081 15.8 1.0 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 GAP89143.1 - 0.0083 15.9 0.8 0.0083 15.9 0.8 3.2 3 0 0 3 3 3 1 RING-like zinc finger zf-ANAPC11 PF12861.7 GAP89143.1 - 0.021 14.9 1.2 0.056 13.5 1.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PQ-loop PF04193.14 GAP89143.1 - 0.071 12.9 1.7 0.2 11.4 1.7 1.9 1 0 0 1 1 1 0 PQ loop repeat Tetraspanin PF00335.20 GAP89143.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family zf-C3H2C3 PF17122.5 GAP89143.1 - 1.9 8.6 4.3 8 6.6 1.2 2.5 2 0 0 2 2 2 0 Zinc-finger FANCL_C PF11793.8 GAP89143.1 - 5.1 7.3 5.1 3 8.1 2.4 2.0 2 1 0 2 2 2 0 FANCL C-terminal domain NAD_binding_6 PF08030.12 GAP89144.1 - 0.32 11.1 1.2 0.56 10.3 1.1 1.5 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Fungal_trans PF04082.18 GAP89145.1 - 8.3e-12 44.7 0.0 1.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HAGH_C PF16123.5 GAP89146.1 - 3.7e-22 78.6 0.6 6.7e-22 77.8 0.6 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 GAP89146.1 - 1.2e-16 61.3 3.3 1.5e-10 41.4 0.3 2.1 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAP89146.1 - 0.006 16.1 0.3 0.05 13.1 0.3 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1236 PF06823.12 GAP89146.1 - 0.069 13.0 0.0 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) BcrAD_BadFG PF01869.20 GAP89146.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Peripla_BP_4 PF13407.6 GAP89146.1 - 0.12 11.9 1.9 0.45 10.0 0.7 2.0 2 0 0 2 2 2 0 Periplasmic binding protein domain Las1 PF04031.13 GAP89147.1 - 9.6e-61 204.4 1.0 1.6e-60 203.7 1.0 1.4 1 0 0 1 1 1 1 Las1-like PfkB PF00294.24 GAP89150.1 - 2e-08 33.9 0.0 5.5e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase MFS_1 PF07690.16 GAP89152.1 - 3.3e-21 75.6 48.1 1e-13 51.0 26.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Hid1 PF12722.7 GAP89153.1 - 0 1015.6 0.0 0 1015.4 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 GAP89153.1 - 1e-102 344.6 0.0 1.3e-102 344.3 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Cation_efflux PF01545.21 GAP89154.1 - 6.5e-10 39.1 13.7 9.1e-10 38.6 13.7 1.2 1 0 0 1 1 1 1 Cation efflux family DUF5504 PF17608.2 GAP89154.1 - 0.14 12.3 0.5 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5504) DUF5056 PF16479.5 GAP89154.1 - 2 8.7 4.1 26 5.1 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) PIG-Y PF15159.6 GAP89155.1 - 1.3e-21 77.3 8.9 2e-21 76.7 8.9 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y zf-MYND PF01753.18 GAP89156.1 - 4.3e-08 33.1 19.6 1.3e-07 31.6 19.6 1.9 1 0 0 1 1 1 1 MYND finger SelP_N PF04592.14 GAP89156.1 - 0.91 8.9 18.5 0.35 10.2 10.6 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region IF4E PF01652.18 GAP89157.1 - 2.1e-38 131.6 0.0 2.8e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E EF-hand_9 PF14658.6 GAP89158.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain Zn_clus PF00172.18 GAP89159.1 - 1.6e-08 34.5 7.8 3.6e-08 33.4 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mid1 PF12929.7 GAP89160.1 - 3.9e-131 438.2 4.6 5.6e-131 437.6 4.6 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 GAP89160.1 - 0.002 18.7 4.8 0.035 14.7 1.6 2.5 2 0 0 2 2 2 2 Fz domain RAMP4 PF06624.12 GAP89161.1 - 6.5e-24 83.8 0.1 7.1e-24 83.6 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF1206 PF06724.11 GAP89161.1 - 0.032 14.3 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) SMAP PF15477.6 GAP89162.1 - 3.1e-13 50.5 3.0 3.1e-13 50.5 3.0 4.6 2 1 0 2 2 2 1 Small acidic protein family Sec10 PF07393.11 GAP89163.1 - 2.3e-164 548.6 0.0 2.8e-164 548.3 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 GAP89163.1 - 2.6e-06 27.2 0.0 6.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP89163.1 - 9.2e-06 25.4 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 GAP89163.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 F-box bZIP_2 PF07716.15 GAP89164.1 - 0.011 15.8 11.7 0.02 14.9 11.7 1.4 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 GAP89164.1 - 0.11 12.7 11.1 0.2 11.8 11.0 1.5 1 1 0 1 1 1 0 bZIP transcription factor SR-25 PF10500.9 GAP89164.1 - 3.1 7.3 20.7 0.72 9.4 11.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SNF2_N PF00176.23 GAP89165.1 - 1e-59 202.1 0.0 1.8e-59 201.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 GAP89165.1 - 2.3e-08 34.2 13.6 4.8e-08 33.2 13.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAP89165.1 - 3.1e-08 33.3 12.7 7.3e-08 32.1 12.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP89165.1 - 2.5e-07 30.4 12.4 5.8e-07 29.3 12.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP89165.1 - 3.5e-07 30.0 9.8 8e-07 28.8 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP89165.1 - 9.2e-07 28.8 6.7 9.2e-07 28.8 6.7 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAP89165.1 - 4.3e-06 26.9 9.3 1.3e-05 25.4 9.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 GAP89165.1 - 4.3e-06 27.0 0.0 1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 GAP89165.1 - 0.0002 21.3 12.0 0.00066 19.6 12.3 1.8 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAP89165.1 - 0.00043 20.1 13.5 0.0014 18.5 13.2 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAP89165.1 - 0.0015 18.7 9.0 0.0054 16.9 8.8 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 GAP89165.1 - 0.008 16.3 6.0 0.018 15.2 6.0 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 GAP89165.1 - 0.022 14.8 4.9 0.052 13.6 4.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HDV_ag PF01517.18 GAP89165.1 - 0.098 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen zf-Nse PF11789.8 GAP89165.1 - 0.24 11.2 4.5 0.57 10.0 4.5 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 GAP89165.1 - 0.72 9.7 11.3 2.1 8.2 11.3 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IGR PF09597.10 GAP89166.1 - 1.5e-07 31.4 0.2 2.3e-07 30.8 0.2 1.3 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.25 GAP89167.1 - 6.6e-65 219.1 0.0 8e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89167.1 - 5.1e-35 121.0 0.0 7.6e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP89167.1 - 0.00014 21.3 0.1 0.00028 20.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAP89167.1 - 0.011 14.7 0.0 2.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 GAP89167.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Frag1 PF10277.9 GAP89168.1 - 8.4e-40 136.6 12.6 9.8e-40 136.4 12.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EMP70 PF02990.16 GAP89168.1 - 0.047 12.3 2.6 0.068 11.8 2.6 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Eisosome1 PF12757.7 GAP89169.1 - 4.2e-37 127.2 9.4 4.2e-37 127.2 9.4 4.0 3 2 1 4 4 4 1 Eisosome protein 1 Y_phosphatase3 PF13350.6 GAP89170.1 - 1e-39 136.9 0.0 2.7e-39 135.5 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 GAP89170.1 - 0.00053 19.6 0.0 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAP89170.1 - 0.00072 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 GAP89170.1 - 0.004 16.1 0.0 0.017 14.1 0.0 1.8 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain DSPc PF00782.20 GAP89170.1 - 0.13 12.0 0.0 0.54 10.1 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Methyltransf_25 PF13649.6 GAP89171.1 - 2.2e-16 60.3 0.0 4.1e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP89171.1 - 2.7e-14 53.7 0.0 6.1e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP89171.1 - 3.7e-12 46.4 0.0 6.6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP89171.1 - 8.6e-12 45.6 0.0 1.7e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP89171.1 - 5.5e-09 36.0 0.0 9.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP89171.1 - 7.2e-08 32.0 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAP89171.1 - 0.00071 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 GAP89171.1 - 0.0012 19.9 0.0 0.0027 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 GAP89171.1 - 0.0037 16.5 0.0 0.84 8.8 0.0 2.3 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family SpoU_sub_bind PF08032.12 GAP89171.1 - 0.03 14.6 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Methyltransf_16 PF10294.9 GAP89171.1 - 0.058 13.1 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Polyketide_cyc PF03364.20 GAP89172.1 - 6.3e-21 74.9 0.0 3.4e-20 72.6 0.0 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 GAP89172.1 - 0.1 12.9 3.0 1 9.6 0.7 2.5 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport TPR_19 PF14559.6 GAP89174.1 - 6.4e-15 55.4 10.4 6.5e-08 33.0 0.5 4.7 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAP89174.1 - 2.3e-09 36.7 2.3 0.00068 19.6 1.3 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAP89174.1 - 1.2e-08 34.5 0.1 0.00013 21.6 0.0 3.5 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.6 GAP89174.1 - 1.7e-08 34.9 1.4 5.4e-06 27.0 1.0 3.5 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAP89174.1 - 3.2e-07 30.6 5.4 0.00011 22.7 0.3 4.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAP89174.1 - 3.2e-07 30.3 0.5 0.0042 17.4 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAP89174.1 - 7.3e-07 28.9 0.4 0.0066 16.6 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP89174.1 - 4.7e-06 26.9 1.6 3.4 8.5 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP89174.1 - 1.6e-05 24.5 0.2 0.013 15.3 0.7 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAP89174.1 - 7.6e-05 22.8 2.1 0.006 16.7 0.4 2.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 GAP89174.1 - 0.00014 22.1 5.7 1.2 9.5 0.1 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAP89174.1 - 0.0014 18.9 7.5 0.06 13.6 3.2 4.1 2 2 3 5 5 5 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 GAP89174.1 - 0.056 13.4 0.0 7.9 6.4 0.0 2.5 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal ChAPs PF09295.10 GAP89174.1 - 0.08 11.9 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 GAP89174.1 - 0.1 12.7 1.5 5.5 7.3 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Stk19 PF10494.9 GAP89174.1 - 0.11 12.2 0.1 0.45 10.2 0.1 1.9 1 1 0 1 1 1 0 Serine-threonine protein kinase 19 DUF4129 PF13559.6 GAP89174.1 - 0.42 10.9 2.9 21 5.5 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) BTAD PF03704.17 GAP89174.1 - 0.81 10.1 5.4 0.41 11.1 0.4 2.9 3 1 1 4 4 4 0 Bacterial transcriptional activator domain Adaptin_N PF01602.20 GAP89175.1 - 5.9e-82 275.9 0.3 1.1e-81 275.0 0.3 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAP89175.1 - 7e-05 22.9 0.4 0.02 15.0 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAP89175.1 - 0.01 16.2 1.9 1.4 9.4 0.0 4.1 3 1 1 4 4 4 0 HEAT repeats HEAT PF02985.22 GAP89175.1 - 0.091 13.1 0.1 17 6.0 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat AP3D1 PF06375.11 GAP89175.1 - 3.4 7.9 11.1 24 5.1 0.0 2.7 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 RhoGAP PF00620.27 GAP89176.1 - 1.8e-15 57.1 0.1 4.7e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 GAP89176.1 - 2e-13 50.2 0.0 4.1e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 GAP89176.1 - 2.3e-11 43.8 0.0 6.4e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DOT1 PF08123.13 GAP89177.1 - 5.4e-73 244.9 0.1 9.9e-73 244.0 0.1 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 GAP89177.1 - 0.017 15.8 0.0 0.046 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAP89177.1 - 0.025 14.4 0.1 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain ATG16 PF08614.11 GAP89178.1 - 3.3e-49 167.9 6.6 3.7e-49 167.7 6.6 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Metal_resist PF13801.6 GAP89178.1 - 0.0021 18.2 4.1 0.0021 18.2 4.1 1.7 2 0 0 2 2 2 1 Heavy-metal resistance HAUS-augmin3 PF14932.6 GAP89178.1 - 0.0092 15.6 5.2 0.0092 15.6 5.2 1.7 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 Seryl_tRNA_N PF02403.22 GAP89178.1 - 0.012 15.9 3.5 0.012 15.9 3.5 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Golgin_A5 PF09787.9 GAP89178.1 - 0.031 13.8 5.3 0.05 13.1 5.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Lebercilin PF15619.6 GAP89178.1 - 0.14 11.8 11.4 0.03 14.0 8.1 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease UPF0242 PF06785.11 GAP89178.1 - 0.17 12.0 3.5 0.31 11.1 3.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 GAP89178.1 - 0.22 12.0 17.2 6.5 7.3 0.1 2.9 2 1 1 3 3 3 0 Apg6 coiled-coil region FAM76 PF16046.5 GAP89178.1 - 0.4 10.0 5.9 0.38 10.1 4.6 1.5 2 0 0 2 2 2 0 FAM76 protein Cep57_CLD_2 PF14197.6 GAP89178.1 - 0.99 9.5 16.4 1.9 8.7 3.2 3.5 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 FlgN PF05130.12 GAP89178.1 - 2.2 8.8 11.3 5.9 7.4 8.9 2.2 2 0 0 2 2 2 0 FlgN protein DUF3450 PF11932.8 GAP89178.1 - 3.2 7.0 10.7 1.3 8.2 5.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) KELK PF15796.5 GAP89178.1 - 3.9 8.0 13.5 0.68 10.4 4.9 2.8 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase YabA PF06156.13 GAP89178.1 - 8.4 7.1 7.1 1.5 9.5 2.6 2.1 3 0 0 3 3 3 0 Initiation control protein YabA Forkhead PF00250.18 GAP89179.1 - 4.2e-35 119.9 0.1 7.6e-35 119.0 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain ATG101 PF07855.12 GAP89180.1 - 7.4e-54 181.9 0.0 8.7e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 PH PF00169.29 GAP89181.1 - 8.1e-26 90.6 0.3 8.1e-14 52.0 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 GAP89181.1 - 6.1e-11 42.7 0.7 9.3e-05 22.8 0.2 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 GAP89181.1 - 3.4e-09 37.1 4.4 0.00053 20.4 0.5 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 GAP89181.1 - 0.0028 17.7 0.2 0.03 14.4 0.1 2.4 2 1 0 2 2 2 1 PH domain PH_8 PF15409.6 GAP89181.1 - 0.0045 17.2 0.0 0.0096 16.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PNRC PF15365.6 GAP89181.1 - 0.37 10.6 1.8 0.78 9.6 1.8 1.6 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif Cellulase PF00150.18 GAP89182.1 - 2.9e-18 66.3 1.8 7.2e-18 65.0 1.8 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 GAP89184.1 - 7.7e-61 201.8 0.0 3.3e-21 74.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAP89184.1 - 6.7e-10 38.6 0.0 1.4e-05 24.7 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAP89184.1 - 3.2e-09 36.5 0.0 0.0051 16.6 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 GAP89184.1 - 1.4e-07 31.3 0.1 0.076 13.0 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 GAP89184.1 - 0.00017 21.6 0.0 0.76 9.9 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_8 PF11835.8 GAP89184.1 - 0.00075 19.7 0.0 0.23 11.7 0.0 2.4 2 0 0 2 2 2 2 RRM-like domain RRM_7 PF16367.5 GAP89184.1 - 0.0019 18.3 0.0 1.8 8.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 GAP89184.1 - 0.21 11.7 0.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Pkinase PF00069.25 GAP89185.1 - 5.3e-50 170.2 0.0 1.4e-49 168.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89185.1 - 2.7e-23 82.6 0.0 5.7e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP89185.1 - 0.00011 22.2 2.7 0.00032 20.7 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 GAP89185.1 - 0.0014 18.3 0.2 0.0033 17.1 0.2 1.6 1 0 0 1 1 1 1 RIO1 family CCDC84 PF14968.6 GAP89185.1 - 0.12 12.0 2.3 0.22 11.1 2.3 1.4 1 0 0 1 1 1 0 Coiled coil protein 84 Choline_kinase PF01633.20 GAP89185.1 - 0.26 10.8 1.0 0.35 10.4 0.2 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase RRM_1 PF00076.22 GAP89186.1 - 9.8e-05 22.1 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 GAP89186.1 - 0.062 13.6 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Ribosomal_L2_C PF03947.18 GAP89187.1 - 2.2e-42 144.2 4.9 3.9e-42 143.4 4.9 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 GAP89187.1 - 2.1e-14 53.2 0.1 5.2e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.24 GAP89188.1 - 6.7e-66 222.6 0.1 7.6e-66 222.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 GAP89188.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 GAP89189.1 - 7.4e-42 143.8 2.5 1.2e-41 143.0 2.5 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 GAP89189.1 - 5e-21 75.8 1.7 5e-21 75.8 1.7 2.5 2 0 0 2 2 2 1 Telomerase activating protein Est1 CNP_C_terminal PF17839.1 GAP89189.1 - 0.0073 17.0 0.3 0.2 12.4 0.0 2.9 2 0 0 2 2 2 1 C-terminal domain of cyclic nucleotide phosphodiesterase G10 PF01125.17 GAP89191.1 - 5.9e-62 207.8 3.0 6.6e-62 207.6 3.0 1.0 1 0 0 1 1 1 1 G10 protein Complex1_LYR_2 PF13233.6 GAP89192.1 - 6e-07 30.1 0.1 8e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAP89192.1 - 2e-05 24.6 0.1 4.3e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) NodA PF02474.15 GAP89192.1 - 0.059 13.0 0.7 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 Nodulation protein A (NodA) RNA_pol_L_2 PF13656.6 GAP89193.1 - 8.6e-32 108.7 0.0 1.1e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 GAP89193.1 - 1.4e-13 50.1 0.0 1.9e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2315 PF10231.9 GAP89193.1 - 0.051 13.7 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Apoptogenic protein 1 TP_methylase PF00590.20 GAP89193.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkinase PF00069.25 GAP89195.1 - 6.7e-50 169.9 0.0 1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89195.1 - 1e-26 93.8 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP89195.1 - 0.031 13.6 0.0 0.067 12.5 0.0 1.6 1 1 1 2 2 2 0 Kinase-like Kdo PF06293.14 GAP89195.1 - 0.038 13.3 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 GAP89196.1 - 6.8e-56 189.5 0.1 1.2e-50 172.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89196.1 - 9.8e-35 120.1 0.0 8.4e-33 113.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAP89196.1 - 1.5e-09 37.6 0.0 5.2e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 GAP89196.1 - 5.1e-05 23.3 0.1 0.00011 22.3 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAP89196.1 - 0.0012 17.7 0.0 0.0024 16.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAP89196.1 - 0.13 11.6 0.1 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sybindin PF04099.12 GAP89197.1 - 2.3e-23 82.7 0.0 3.1e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family DUF3275 PF11679.8 GAP89197.1 - 0.051 13.5 1.9 0.068 13.1 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) MGC-24 PF05283.11 GAP89197.1 - 0.13 12.7 5.4 0.19 12.1 5.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 GAP89197.1 - 0.26 11.3 14.4 0.36 10.8 14.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.8 GAP89197.1 - 1.8 7.7 18.7 2.4 7.3 18.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peroxin-3 PF04882.12 GAP89198.1 - 5.3e-170 566.4 0.0 6.2e-170 566.2 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 WD40 PF00400.32 GAP89199.1 - 2.5e-11 43.9 0.3 0.89 10.5 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP89199.1 - 0.006 16.9 0.0 3.7 7.9 0.0 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain NOA36 PF06524.12 GAP89199.1 - 4 6.7 10.4 5.8 6.1 10.4 1.2 1 0 0 1 1 1 0 NOA36 protein HSA PF07529.13 GAP89200.1 - 3e-13 49.9 1.2 3e-13 49.9 1.2 5.4 5 0 0 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.6 GAP89200.1 - 2.6e-07 30.8 2.3 3.2e-07 30.5 0.3 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAP89200.1 - 0.03 14.5 0.0 0.075 13.2 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain G-patch_2 PF12656.7 GAP89201.1 - 3.6e-17 62.2 0.6 1.5e-16 60.2 0.6 2.1 1 0 0 1 1 1 1 G-patch domain CMAS PF02353.20 GAP89202.1 - 1.9e-61 207.7 0.0 2.4e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 GAP89202.1 - 2.7e-09 37.5 0.0 5.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP89202.1 - 7.7e-09 36.2 0.0 1.6e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP89202.1 - 2.6e-08 33.9 0.0 4.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 GAP89202.1 - 0.027 14.0 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 GAP89202.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 GAP89202.1 - 0.11 13.2 0.0 0.28 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain EF-hand_4 PF12763.7 GAP89203.1 - 2e-27 95.2 0.0 4.7e-15 55.4 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 GAP89203.1 - 0.0056 17.1 0.2 1 9.8 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair E3_binding PF02817.17 GAP89203.1 - 0.037 14.4 0.8 0.21 11.9 0.1 2.7 3 0 0 3 3 3 0 e3 binding domain EF-hand_6 PF13405.6 GAP89203.1 - 0.17 11.9 0.1 29 5.0 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain MAP65_ASE1 PF03999.12 GAP89204.1 - 4.1e-73 247.1 15.6 9e-73 245.9 14.2 1.9 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Prominin PF05478.11 GAP89204.1 - 0.037 12.0 3.6 1.8 6.5 0.1 2.4 2 1 0 2 2 2 0 Prominin BAR_3 PF16746.5 GAP89204.1 - 0.052 13.3 4.2 0.079 12.6 0.7 2.4 2 0 0 2 2 2 0 BAR domain of APPL family Mit_KHE1 PF10173.9 GAP89204.1 - 0.16 12.0 2.3 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related CC2-LZ PF16516.5 GAP89204.1 - 0.19 12.1 6.2 1 9.7 0.3 3.4 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Baculo_PEP_C PF04513.12 GAP89204.1 - 0.2 11.7 0.0 9.1 6.3 0.1 3.1 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.11 GAP89204.1 - 4.8 5.9 14.2 0.043 12.7 0.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF812) EF-hand_4 PF12763.7 GAP89205.1 - 0.0001 22.2 0.1 0.00035 20.5 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand INSIG PF07281.12 GAP89206.1 - 1.5e-70 237.1 1.9 2.1e-70 236.7 1.9 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) bHLH-MYC_N PF14215.6 GAP89206.1 - 0.072 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal LON_substr_bdg PF02190.16 GAP89207.1 - 1.7e-17 64.0 0.0 2.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-RING_UBOX PF13445.6 GAP89207.1 - 2.6e-05 24.2 8.0 4.4e-05 23.4 6.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 GAP89207.1 - 2.9e-05 24.1 6.6 6.9e-05 22.9 6.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 GAP89207.1 - 0.0017 18.2 5.7 0.0025 17.6 4.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP89207.1 - 0.0067 16.3 3.9 0.016 15.1 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP89207.1 - 0.038 13.9 3.2 0.08 12.8 3.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP89207.1 - 0.066 13.6 6.9 0.11 12.8 5.8 2.0 2 0 0 2 2 2 0 Ring finger domain Band_7_C PF16200.5 GAP89207.1 - 0.15 12.1 0.3 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 C-terminal region of band_7 zf-RING_5 PF14634.6 GAP89207.1 - 0.16 11.9 3.7 0.44 10.5 3.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain efThoc1 PF11957.8 GAP89208.1 - 1.1e-128 430.0 3.7 1.4e-128 429.6 3.7 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 GAP89208.1 - 2.8e-35 121.7 0.0 5.2e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 GAP89208.1 - 0.00014 21.9 0.0 0.00037 20.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GAP89208.1 - 0.0038 17.5 0.0 0.35 11.2 0.0 2.9 2 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAP89208.1 - 0.012 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAP89208.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 GAP89208.1 - 0.046 14.1 0.1 0.3 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 GAP89208.1 - 0.048 14.2 0.0 0.15 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAP89208.1 - 0.089 12.8 0.6 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Aquarius_N PF16399.5 GAP89209.1 - 0 1096.5 0.1 0 1095.9 0.1 1.2 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 GAP89209.1 - 5.2e-27 94.8 0.0 9.6e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAP89209.1 - 3.6e-22 79.4 0.0 1.7e-21 77.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAP89209.1 - 1.4e-07 31.5 0.0 0.00043 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 GAP89209.1 - 1.2e-05 25.3 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAP89209.1 - 1.8e-05 25.1 0.0 4.9e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP89209.1 - 0.00082 19.8 0.2 0.0044 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 GAP89209.1 - 0.0019 18.6 0.0 0.01 16.3 0.0 2.3 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 GAP89209.1 - 0.0035 16.7 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 GAP89209.1 - 0.012 15.9 0.6 0.17 12.2 0.2 2.9 2 1 1 3 3 3 0 AAA domain UvrD_C_2 PF13538.6 GAP89209.1 - 0.014 15.2 0.2 0.047 13.5 0.2 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 GAP89209.1 - 0.048 12.9 1.1 0.078 12.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 GAP89209.1 - 0.049 13.6 0.0 0.54 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 GAP89209.1 - 0.054 13.2 0.1 2.7 7.6 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 GAP89209.1 - 0.061 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 GAP89209.1 - 0.076 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DEAD PF00270.29 GAP89209.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase NB-ARC PF00931.22 GAP89209.1 - 0.18 11.0 0.0 0.4 9.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 GAP89209.1 - 0.18 11.0 0.4 0.58 9.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin FAM222A PF15258.6 GAP89209.1 - 0.23 10.5 0.1 0.38 9.8 0.1 1.2 1 0 0 1 1 1 0 Protein family of FAM222A MIF4G PF02854.19 GAP89210.1 - 1.5e-54 184.8 0.0 2.6e-54 184.1 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 GAP89210.1 - 5.3e-23 81.0 0.4 1.2e-22 79.8 0.4 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 PV-1 PF06637.11 GAP89210.1 - 3.4 6.4 11.2 5.8 5.6 11.2 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DNA_pol_B PF00136.21 GAP89211.1 - 7.3e-114 381.0 0.3 1e-113 380.5 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 GAP89211.1 - 1.9e-66 223.3 0.0 3.3e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 GAP89211.1 - 7.1e-37 127.3 0.0 1.1e-36 126.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 GAP89211.1 - 8.5e-26 89.8 9.0 2.2e-25 88.5 9.0 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 GAP89211.1 - 0.018 14.0 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral PPR_2 PF13041.6 GAP89212.1 - 2.8e-21 75.4 0.4 5.7e-15 55.2 0.0 3.6 2 1 1 3 3 3 2 PPR repeat family PPR_long PF17177.4 GAP89212.1 - 5.4e-08 32.5 0.1 1.1e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 GAP89212.1 - 6.1e-07 29.4 0.3 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 GAP89212.1 - 1.5e-06 28.1 1.0 0.018 15.2 0.0 4.9 5 1 0 5 5 5 2 PPR repeat PPR_1 PF12854.7 GAP89212.1 - 0.00033 20.3 0.4 15 5.4 0.2 4.5 5 1 0 5 5 5 2 PPR repeat DUF1770 PF08589.10 GAP89213.1 - 1.6e-30 106.0 10.0 6.3e-30 104.1 10.0 1.8 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Cwf_Cwc_15 PF04889.12 GAP89213.1 - 0.003 17.3 8.5 0.0038 17.0 8.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 GAP89213.1 - 0.0031 16.9 9.2 0.004 16.5 9.2 1.1 1 0 0 1 1 1 1 NOA36 protein Med13_C PF06333.12 GAP89213.1 - 0.0038 16.5 1.4 0.0046 16.3 1.4 1.1 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain FAM176 PF14851.6 GAP89213.1 - 0.0043 16.7 0.4 0.007 16.0 0.4 1.3 1 0 0 1 1 1 1 FAM176 family Myc_N PF01056.18 GAP89213.1 - 0.011 15.6 1.1 0.016 15.2 1.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.11 GAP89213.1 - 0.02 14.9 3.1 0.026 14.6 3.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal LRS4 PF10422.9 GAP89213.1 - 0.12 12.0 6.9 0.15 11.6 6.9 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Nucleo_P87 PF07267.11 GAP89213.1 - 0.13 11.1 8.0 0.16 10.8 8.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pox_Ag35 PF03286.14 GAP89213.1 - 0.33 10.7 5.0 0.53 10.0 5.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ORC6 PF05460.13 GAP89213.1 - 0.39 10.0 5.9 0.49 9.6 5.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CENP-B_dimeris PF09026.10 GAP89213.1 - 0.4 11.1 18.8 0.67 10.4 18.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SDA1 PF05285.12 GAP89213.1 - 0.59 9.5 5.1 0.73 9.2 5.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 GAP89213.1 - 0.85 7.8 5.2 1 7.5 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 GAP89213.1 - 2.3 7.7 9.6 3 7.4 9.6 1.1 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 GAP89213.1 - 2.9 5.9 14.3 3.8 5.5 14.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 GAP89213.1 - 3.6 7.1 5.2 4.7 6.7 5.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CDC45 PF02724.14 GAP89213.1 - 5.8 5.1 6.0 7.8 4.7 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.6 GAP89213.1 - 6 7.2 11.0 17 5.7 11.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RRN3 PF05327.11 GAP89213.1 - 6.9 5.1 5.7 8.3 4.8 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MGC-24 PF05283.11 GAP89213.1 - 7.1 7.1 6.4 10 6.5 6.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PBP1_TM PF14812.6 GAP89213.1 - 8.5 6.8 21.5 41 4.6 21.5 2.1 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WHIM1 PF15612.6 GAP89214.1 - 3.3e-06 26.5 0.0 7.4e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 eRF1_2 PF03464.15 GAP89215.1 - 1.2e-46 158.4 0.0 1.9e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 GAP89215.1 - 8.3e-41 139.0 0.5 1.6e-40 138.1 0.5 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 GAP89215.1 - 2.6e-22 79.2 0.0 4e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 GAP89215.1 - 3.2e-10 40.4 0.0 1.1e-09 38.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 GAP89215.1 - 3.2e-09 37.2 0.0 5.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor PDT PF00800.18 GAP89216.1 - 9.9e-44 149.3 0.0 2.9e-43 147.8 0.0 2.0 1 1 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 GAP89216.1 - 0.00019 21.1 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 ACT domain Trypan_PARP PF05887.11 GAP89216.1 - 0.001 19.1 0.2 0.0021 18.0 0.2 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) E1_dh PF00676.20 GAP89217.1 - 5.7e-114 380.1 0.5 6.9e-114 379.8 0.5 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 GAP89217.1 - 0.0039 16.4 0.2 0.0079 15.4 0.2 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Velvet PF11754.8 GAP89218.1 - 3.8e-53 181.0 0.2 1.1e-35 123.8 0.0 3.4 2 2 1 3 3 3 2 Velvet factor HTH_Tnp_Tc3_2 PF01498.18 GAP89218.1 - 0.077 13.3 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Transposase NAD_binding_4 PF07993.12 GAP89220.1 - 3.8e-34 118.0 0.0 5.5e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAP89220.1 - 6.1e-27 94.3 0.0 9.4e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAP89220.1 - 9.1e-10 38.4 0.0 2.1e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAP89220.1 - 8.6e-07 29.2 0.0 2.7e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 GAP89220.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 GAP89220.1 - 0.17 10.9 0.0 7.9 5.4 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family SLATT_5 PF18160.1 GAP89221.1 - 0.33 10.3 1.6 0.6 9.4 0.1 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Gpr1_Fun34_YaaH PF01184.19 GAP89222.1 - 3.7e-57 193.3 17.4 4.3e-57 193.1 17.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MAPEG PF01124.18 GAP89224.1 - 3.6e-15 56.0 0.1 4e-15 55.9 0.1 1.0 1 0 0 1 1 1 1 MAPEG family GH131_N PF18271.1 GAP89226.1 - 2.2e-64 217.6 2.6 2.6e-64 217.4 2.6 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 GAP89226.1 - 0.038 13.8 3.6 0.06 13.2 3.6 1.4 1 0 0 1 1 1 0 Polysaccharide lyase MFS_2 PF13347.6 GAP89227.1 - 2e-09 36.5 5.9 2e-09 36.5 5.9 2.7 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.16 GAP89227.1 - 1e-08 34.5 26.5 0.00036 19.6 5.0 3.5 3 1 1 4 4 4 3 Major Facilitator Superfamily PUCC PF03209.15 GAP89227.1 - 5.9e-06 25.5 2.4 1.2e-05 24.5 2.4 1.5 1 0 0 1 1 1 1 PUCC protein Na_H_Exchanger PF00999.21 GAP89228.1 - 3.3e-75 253.2 31.3 4e-75 253.0 31.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 GAP89228.1 - 0.0085 15.8 1.4 0.022 14.4 1.4 1.7 1 0 0 1 1 1 1 PepSY-associated TM region TERF2_RBM PF16772.5 GAP89228.1 - 0.013 14.9 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif NiFe_hyd_3_EhaA PF17367.2 GAP89228.1 - 0.11 12.7 11.9 2.2 8.5 3.9 3.5 2 1 1 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF3054 PF11255.8 GAP89228.1 - 0.23 12.0 10.0 0.35 11.4 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3054) DUF3917 PF13055.6 GAP89228.1 - 8.2 6.9 9.3 2.2 8.7 0.7 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3917) Pkinase PF00069.25 GAP89229.1 - 1.3e-39 136.2 0.0 1.9e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89229.1 - 2.3e-28 99.2 0.0 3.5e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP89229.1 - 0.0003 20.2 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP89229.1 - 0.0024 17.8 0.2 0.37 10.7 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAP89229.1 - 0.033 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MFS_1 PF07690.16 GAP89230.1 - 2.8e-39 135.0 23.6 2.8e-39 135.0 23.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Aa_trans PF01490.18 GAP89231.1 - 6.7e-25 87.6 41.4 1e-24 87.0 41.4 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein RhoGAP PF00620.27 GAP89232.1 - 2.4e-38 131.4 0.0 4.1e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DUF3543 PF12063.8 GAP89233.1 - 6.8e-93 310.7 0.1 1.1e-92 310.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 GAP89233.1 - 2e-61 207.7 0.0 3.5e-61 206.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89233.1 - 7.5e-42 143.4 0.0 1.6e-41 142.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 GAP89233.1 - 0.093 12.9 0.0 0.62 10.2 0.1 2.2 2 0 0 2 2 2 0 ABC1 family Pox_ser-thr_kin PF05445.11 GAP89233.1 - 0.23 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Aminotran_3 PF00202.21 GAP89234.1 - 3.2e-121 404.8 0.0 3.7e-121 404.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 GAP89234.1 - 0.0011 18.3 0.0 0.0035 16.7 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 GAP89234.1 - 0.0021 17.3 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_transf_22 PF03901.17 GAP89235.1 - 5.3e-77 259.8 17.3 7e-77 259.4 17.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Cullin PF00888.22 GAP89236.1 - 7.1e-173 576.5 0.0 9.5e-173 576.1 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 GAP89236.1 - 7.7e-26 89.9 1.1 2e-25 88.6 1.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain ABC_membrane PF00664.23 GAP89237.1 - 8.6e-86 288.0 24.2 3.8e-47 161.2 5.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAP89237.1 - 4.6e-51 172.9 0.1 1e-28 100.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAP89237.1 - 6.3e-09 35.6 4.7 0.0061 16.0 0.1 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 GAP89237.1 - 2.4e-05 24.4 0.3 0.24 11.5 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP89237.1 - 3.5e-05 23.8 0.2 0.2 11.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAP89237.1 - 0.00017 22.0 0.8 0.036 14.5 0.4 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 GAP89237.1 - 0.0014 19.1 0.0 0.2 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 GAP89237.1 - 0.0036 17.0 1.1 1.1 9.1 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 GAP89237.1 - 0.0063 16.4 0.6 0.054 13.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 GAP89237.1 - 0.024 14.7 1.4 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 GAP89237.1 - 0.035 13.8 0.7 1.6 8.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 GAP89237.1 - 0.053 13.9 0.0 4.2 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 GAP89237.1 - 0.073 13.3 2.0 19 5.6 0.1 3.2 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 GAP89237.1 - 0.083 13.1 0.7 23 5.3 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 GAP89237.1 - 0.14 11.7 0.1 16 4.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 GAP89237.1 - 0.16 11.6 0.3 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 GAP89237.1 - 0.3 11.2 4.6 0.44 10.6 0.3 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain AIG1 PF04548.16 GAP89237.1 - 0.35 10.2 1.3 8.1 5.7 0.1 2.2 2 0 0 2 2 2 0 AIG1 family DUF2841 PF11001.8 GAP89238.1 - 1.3e-36 125.4 0.1 1.3e-36 125.4 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) p450 PF00067.22 GAP89239.1 - 5.4e-46 157.3 0.0 3.3e-41 141.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF1749 PF08538.10 GAP89240.1 - 1.4e-81 273.9 0.0 1.7e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 GAP89240.1 - 1.3e-09 39.0 0.6 1.7e-09 38.6 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP89240.1 - 1e-06 28.2 0.0 0.00023 20.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP89240.1 - 1.7e-05 24.6 0.1 0.00037 20.2 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP89240.1 - 0.00032 20.3 0.0 0.41 10.1 0.0 2.9 2 1 1 3 3 3 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 GAP89240.1 - 0.023 14.6 0.0 0.06 13.2 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase RTP1_C1 PF10363.9 GAP89241.1 - 0.045 13.9 0.0 0.52 10.5 0.0 2.8 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 GAP89241.1 - 0.046 14.0 4.9 0.66 10.4 0.3 4.5 5 0 0 5 5 5 0 HEAT repeat RRM_1 PF00076.22 GAP89242.1 - 1.6e-13 50.2 0.0 4e-07 29.7 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAP89242.1 - 0.005 16.7 0.0 0.02 14.8 0.0 2.0 2 1 0 2 2 2 1 Occluded RNA-recognition motif SelP_N PF04592.14 GAP89242.1 - 1.8 7.9 11.2 3.1 7.2 11.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ANAPC4_WD40 PF12894.7 GAP89243.1 - 2.5e-05 24.5 0.0 5 7.5 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAP89243.1 - 0.017 16.0 10.3 5.1 8.1 0.1 5.9 6 0 0 6 6 6 0 WD domain, G-beta repeat IKI3 PF04762.12 GAP89243.1 - 0.069 11.1 0.0 1.4 6.8 0.0 2.6 3 0 0 3 3 3 0 IKI3 family MoaC PF01967.21 GAP89244.1 - 3.3e-53 179.4 2.8 5.3e-53 178.8 2.8 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 GAP89244.1 - 4e-37 127.0 0.0 3e-36 124.2 0.0 2.1 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 GAP89244.1 - 1.9e-24 87.0 0.0 3.4e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 GAP89244.1 - 1e-05 25.9 0.0 3.5e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 GAP89244.1 - 0.054 13.6 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 4Fe-4S single cluster domain ELO PF01151.18 GAP89246.1 - 8.3e-79 264.6 11.4 9.8e-79 264.4 11.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family GMC_oxred_N PF00732.19 GAP89247.1 - 1.8e-45 155.6 0.3 3.3e-45 154.7 0.2 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP89247.1 - 1.2e-26 94.0 0.0 2.5e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAP89247.1 - 0.00011 21.5 0.2 0.00022 20.6 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP89247.1 - 0.00032 19.9 6.3 0.0013 17.9 6.3 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAP89247.1 - 0.00036 20.7 1.3 0.0016 18.6 1.3 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAP89247.1 - 0.0014 18.0 0.8 0.0022 17.3 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP89247.1 - 0.029 14.0 0.7 0.48 9.9 0.3 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAP89247.1 - 0.038 12.7 0.8 0.058 12.1 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 GAP89247.1 - 0.047 12.9 0.6 0.11 11.7 0.6 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 GAP89247.1 - 0.18 11.1 1.2 0.29 10.4 1.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 GAP89247.1 - 0.39 10.3 3.4 0.61 9.6 3.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pilt PF15453.6 GAP89249.1 - 7.3 5.9 8.7 12 5.2 8.7 1.3 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions FAD_binding_4 PF01565.23 GAP89250.1 - 9.2e-23 80.5 1.9 2.7e-22 79.0 1.9 1.9 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP89250.1 - 2e-08 34.2 0.0 3.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like F-box-like PF12937.7 GAP89252.1 - 5.4e-11 42.2 0.1 2.4e-10 40.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 GAP89252.1 - 5.6e-11 41.6 11.6 0.17 12.0 0.0 7.9 9 0 0 9 9 9 3 Leucine Rich repeat F-box PF00646.33 GAP89252.1 - 2.3e-07 30.5 0.3 1e-06 28.5 0.3 2.2 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 GAP89252.1 - 6.7e-05 23.2 8.3 0.58 10.7 0.0 6.0 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 GAP89252.1 - 0.00069 19.8 6.5 20 6.2 0.0 6.3 7 0 0 7 7 7 1 Leucine Rich Repeat p47_phox_C PF08944.11 GAP89252.1 - 0.065 12.7 1.3 0.17 11.3 0.1 2.3 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain SAM_Ste50p PF09235.10 GAP89252.1 - 1.5 9.2 3.8 14 6.0 0.0 3.4 2 1 1 3 3 3 0 Ste50p, sterile alpha motif HET PF06985.11 GAP89253.1 - 1.7e-24 86.9 0.1 1.7e-24 86.9 0.1 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Acetyltransf_7 PF13508.7 GAP89254.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP89254.1 - 0.039 14.2 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CVNH PF08881.10 GAP89255.1 - 5.7e-15 55.8 1.5 7e-15 55.5 1.5 1.1 1 0 0 1 1 1 1 CVNH domain ABA_GPCR PF12430.8 GAP89256.1 - 1e-61 207.9 0.7 1e-61 207.9 0.7 1.7 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 GAP89256.1 - 2.2e-26 91.7 0.2 3.1e-25 88.0 0.0 2.5 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal ATG22 PF11700.8 GAP89256.1 - 0.054 12.1 4.1 0.14 10.7 0.3 2.2 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like MRP-L46 PF11788.8 GAP89257.1 - 2.2e-30 105.9 0.7 5.5e-30 104.5 0.1 1.9 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 GAP89257.1 - 0.0078 16.3 0.1 0.019 15.0 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain Pinin_SDK_memA PF04696.13 GAP89258.1 - 1.6e-28 99.3 14.2 1.6e-28 99.3 14.2 3.2 3 1 0 3 3 3 1 pinin/SDK/memA/ protein conserved region Pex26 PF07163.12 GAP89258.1 - 0.0003 20.2 2.9 0.0003 20.2 2.9 2.4 3 0 0 3 3 3 1 Pex26 protein DUF1752 PF08550.10 GAP89258.1 - 0.26 11.2 1.0 2 8.3 0.0 2.8 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1752) Abhydrolase_1 PF00561.20 GAP89259.1 - 1.2e-21 77.5 0.0 5.7e-21 75.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP89259.1 - 5.4e-17 63.1 0.9 7.7e-17 62.6 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP89259.1 - 8.4e-09 35.0 0.0 2.5e-08 33.5 0.0 1.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 GAP89259.1 - 0.032 14.6 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus PhoLip_ATPase_C PF16212.5 GAP89260.1 - 1.6e-80 270.4 17.7 1.6e-80 270.4 17.7 1.9 2 1 1 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAP89260.1 - 8.1e-27 92.7 3.5 2.1e-26 91.4 3.5 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 GAP89260.1 - 4.1e-12 46.0 0.0 8.3e-11 41.8 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAP89260.1 - 1.1e-10 42.2 3.5 1.2e-06 29.0 1.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAP89260.1 - 3.5e-08 33.2 0.0 6.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAP89260.1 - 0.0011 18.7 0.5 0.0045 16.8 0.5 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pyr_redox_2 PF07992.14 GAP89261.1 - 2.3e-54 184.6 0.0 3e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP89261.1 - 1.6e-11 44.6 0.0 5.9e-10 39.6 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP89261.1 - 0.016 14.5 2.9 0.91 8.7 0.0 2.8 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase XhlA PF10779.9 GAP89261.1 - 0.11 12.7 3.3 12 6.2 1.0 2.7 2 0 0 2 2 2 0 Haemolysin XhlA DHR10 PF18595.1 GAP89261.1 - 0.14 12.2 0.4 0.3 11.2 0.4 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Acetyltransf_7 PF13508.7 GAP89262.1 - 4.2e-08 33.5 0.0 2.1e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAP89262.1 - 8.3e-08 32.2 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP89262.1 - 1e-07 32.2 0.0 1.7e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 GAP89262.1 - 0.00026 21.1 0.2 0.00079 19.5 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAP89262.1 - 0.00096 19.2 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 GAP89262.1 - 0.0056 16.6 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein AA_permease_2 PF13520.6 GAP89264.1 - 5.7e-81 272.5 22.8 7.3e-81 272.2 22.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP89264.1 - 5.1e-12 45.1 19.5 6.7e-12 44.7 19.5 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 GAP89264.1 - 0.012 14.4 4.4 0.11 11.1 0.0 2.5 2 0 0 2 2 2 0 Transmembrane amino acid transporter protein p47_phox_C PF08944.11 GAP89265.1 - 2.1 7.9 9.7 6.5 6.3 0.4 3.0 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain LIG3_BRCT PF16759.5 GAP89266.1 - 4.5e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain OLF PF02191.16 GAP89266.1 - 0.012 15.2 0.2 0.017 14.6 0.2 1.1 1 0 0 1 1 1 0 Olfactomedin-like domain BRCT_2 PF16589.5 GAP89266.1 - 0.038 14.4 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 GAP89266.1 - 0.081 12.9 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 twin BRCT domain Use1 PF09753.9 GAP89268.1 - 6e-14 52.4 0.1 3.6e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Membrane fusion protein Use1 BUD22 PF09073.10 GAP89268.1 - 0.027 13.8 10.1 0.046 13.1 10.1 1.3 1 0 0 1 1 1 0 BUD22 Vps53_N PF04100.12 GAP89268.1 - 0.086 11.8 0.7 0.14 11.1 0.7 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF3347 PF11827.8 GAP89268.1 - 0.24 11.6 5.5 2.1 8.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) SlyX PF04102.12 GAP89268.1 - 5.8 7.6 8.1 4.4 8.0 1.0 3.6 3 1 1 4 4 4 0 SlyX DCP2 PF05026.13 GAP89269.1 - 1e-30 105.9 0.6 1.7e-30 105.1 0.6 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 GAP89269.1 - 5.1e-16 58.9 0.0 8.8e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CRIM PF16978.5 GAP89271.1 - 2e-42 144.7 0.0 5.1e-42 143.4 0.0 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 GAP89271.1 - 7.4e-31 106.7 0.0 1.7e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 GAP89271.1 - 0.0041 17.2 0.0 0.011 15.8 0.0 1.7 2 0 0 2 2 2 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 GAP89271.1 - 0.0075 16.5 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 TUG ubiquitin-like domain PBP1_TM PF14812.6 GAP89271.1 - 7.3 7.0 11.2 7 7.1 0.2 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNF PF00209.18 GAP89272.1 - 2.5e-74 250.9 35.0 2.5e-74 250.9 35.0 2.3 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family Cation_ATPase_C PF00689.21 GAP89272.1 - 0.00021 21.0 2.0 0.00021 21.0 2.0 3.3 4 1 1 5 5 5 1 Cation transporting ATPase, C-terminus DUF3810 PF12725.7 GAP89272.1 - 2.8 7.2 7.0 0.1 11.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Pox_I5 PF04713.12 GAP89272.1 - 2.9 8.0 6.8 0.69 10.0 1.9 2.5 2 0 0 2 2 2 0 Poxvirus protein I5 PRCC PF10253.9 GAP89273.1 - 1.1e-31 111.4 5.7 2.9e-31 109.9 5.7 1.8 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting CENP-B_dimeris PF09026.10 GAP89274.1 - 0.68 10.4 8.9 1.2 9.5 8.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3517 PF12030.8 GAP89275.1 - 8.2e-93 311.0 0.0 1.6e-92 310.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 GAP89275.1 - 1.4e-39 136.1 0.2 7.3e-39 133.8 0.2 2.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAP89275.1 - 2.1e-21 76.9 0.3 6.6e-21 75.2 0.3 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pox_A3L PF05288.11 GAP89275.1 - 0.04 13.9 0.2 0.17 11.9 0.2 2.1 1 0 0 1 1 1 0 Poxvirus A3L Protein RNase_P_pop3 PF08228.11 GAP89276.1 - 1.6e-08 34.8 0.0 5.2e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit Pop3 FmrO PF07091.11 GAP89276.1 - 0.062 12.8 0.0 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) CBF PF03914.17 GAP89277.1 - 1.6e-23 83.6 1.1 3.5e-23 82.5 0.0 2.2 3 0 0 3 3 3 1 CBF/Mak21 family NOC3p PF07540.11 GAP89277.1 - 4.6e-23 81.5 0.0 1.8e-22 79.6 0.0 2.1 1 0 0 1 1 1 1 Nucleolar complex-associated protein Adeno_terminal PF02459.15 GAP89277.1 - 0.12 10.8 4.8 0.32 9.3 1.8 2.3 2 0 0 2 2 2 0 Adenoviral DNA terminal protein UPF0113_N PF17833.1 GAP89278.1 - 3.6e-24 85.1 0.0 4.8e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 GAP89278.1 - 3.4e-22 78.5 0.0 5.7e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 GAP89278.1 - 0.17 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain AA_kinase PF00696.28 GAP89279.1 - 8.7e-41 140.1 1.6 1.2e-40 139.6 1.6 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 GAP89279.1 - 1.5e-13 50.5 0.0 9.2e-13 48.0 0.0 2.4 2 1 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.9 GAP89280.1 - 3.2e-68 228.9 2.7 3.9e-68 228.6 2.7 1.1 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.6 GAP89280.1 - 0.0055 17.0 0.0 0.0078 16.5 0.0 1.3 1 0 0 1 1 1 1 Effector protein SprT-like PF10263.9 GAP89280.1 - 0.021 14.7 1.6 0.034 14.0 1.0 1.6 1 1 0 1 1 1 0 SprT-like family Pkinase PF00069.25 GAP89281.1 - 2e-71 240.5 0.0 2.5e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89281.1 - 2.4e-43 148.3 0.0 3.2e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP89281.1 - 1e-06 28.3 0.0 4.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 GAP89281.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAP89281.1 - 0.021 14.5 0.0 0.13 11.9 0.0 2.1 2 1 1 3 3 3 0 RIO1 family APH PF01636.23 GAP89281.1 - 0.041 13.8 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 GAP89281.1 - 0.059 13.0 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 GAP89281.1 - 0.07 12.6 0.1 0.2 11.2 0.0 1.9 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 GAP89281.1 - 0.079 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Levi_coat PF01819.17 GAP89281.1 - 0.25 11.3 2.2 11 6.1 1.9 2.3 2 0 0 2 2 2 0 Levivirus coat protein DUF4267 PF14087.6 GAP89282.1 - 2.5e-17 63.0 6.0 2.9e-17 62.7 6.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) ADH_zinc_N PF00107.26 GAP89283.1 - 3.5e-24 85.2 1.2 1.3e-23 83.4 0.5 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP89283.1 - 2e-18 66.3 1.8 3.6e-18 65.4 1.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 GAP89283.1 - 7.5e-05 23.0 0.1 0.00013 22.2 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_25 PF13649.6 GAP89283.1 - 0.00012 22.7 0.1 0.00026 21.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.19 GAP89283.1 - 0.00023 20.6 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 GAP89283.1 - 0.00025 20.4 0.6 0.00043 19.6 0.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.12 GAP89283.1 - 0.00091 19.8 0.2 0.0025 18.4 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 GAP89283.1 - 0.0056 16.6 0.4 0.0085 16.0 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMAS PF02353.20 GAP89283.1 - 0.0075 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 GAP89283.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PglD_N PF17836.1 GAP89283.1 - 0.023 15.3 0.1 0.046 14.4 0.1 1.6 1 0 0 1 1 1 0 PglD N-terminal domain NAD_binding_2 PF03446.15 GAP89283.1 - 0.028 14.6 0.2 0.043 14.0 0.2 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Cbl_N3 PF02762.14 GAP89283.1 - 0.047 13.6 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain ELFV_dehydrog PF00208.21 GAP89283.1 - 0.084 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XdhC_C PF13478.6 GAP89283.1 - 0.13 12.7 0.1 0.22 12.1 0.1 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Catalase PF00199.19 GAP89284.1 - 1.4e-170 567.5 0.4 1.8e-170 567.2 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GAP89284.1 - 1.4e-18 66.8 0.1 2.6e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 GAP89284.1 - 3.8e-11 43.1 0.0 7.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 GAP89284.1 - 9.3e-10 38.3 0.1 2.2e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain found in long catalases LBP_BPI_CETP_C PF02886.17 GAP89284.1 - 0.084 12.3 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain HD PF01966.22 GAP89285.1 - 4e-09 36.7 0.1 6.1e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 HD domain DUF4112 PF13430.6 GAP89286.1 - 1.2e-29 102.7 0.2 1.6e-29 102.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) VEGFR-2_TMD PF17988.1 GAP89286.1 - 2.2 7.8 5.4 0.47 9.9 1.5 1.8 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain Ribonuc_red_sm PF00268.21 GAP89287.1 - 4.4e-121 403.6 2.2 5.4e-121 403.3 2.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 GAP89288.1 - 7.2e-36 122.5 5.7 1.3e-35 121.7 5.7 1.4 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF2477 PF10631.9 GAP89288.1 - 8.4 7.1 14.0 0.91 10.2 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2477) SNF2_N PF00176.23 GAP89289.1 - 4.4e-65 219.7 0.0 8.1e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP89289.1 - 6.2e-20 71.6 0.0 3.3e-19 69.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP89289.1 - 2.1e-07 31.1 0.0 7.5e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Atg14 PF10186.9 GAP89289.1 - 5.5 6.0 8.6 11 5.0 8.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_S11 PF00411.19 GAP89290.1 - 2.6e-46 156.6 0.7 3.1e-46 156.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Pilus_CpaD PF09476.10 GAP89290.1 - 0.1 12.4 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Ribosomal_L30_N PF08079.12 GAP89291.1 - 3.7e-28 97.6 15.5 6.8e-28 96.7 15.5 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 GAP89291.1 - 8.6e-18 64.0 2.3 8.6e-18 64.0 2.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Fe-S_biosyn PF01521.20 GAP89292.1 - 6.4e-11 42.4 0.0 7.3e-05 22.9 0.0 2.1 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis Mpv17_PMP22 PF04117.12 GAP89294.1 - 2.8e-06 27.5 4.1 1.7e-05 24.9 3.3 2.2 1 1 1 2 2 2 1 Mpv17 / PMP22 family PseudoU_synth_1 PF01416.20 GAP89294.1 - 0.16 12.4 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA pseudouridine synthase LPMO_10 PF03067.15 GAP89295.1 - 1.6e-11 45.2 0.0 2.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading ApbA_C PF08546.11 GAP89296.1 - 1.1e-27 96.7 0.0 1.7e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 GAP89296.1 - 4.4e-24 84.9 0.0 7.3e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Myb_DNA-bind_6 PF13921.6 GAP89297.1 - 4.9e-14 52.3 0.1 4.8e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 GAP89297.1 - 2.5e-11 43.6 0.1 0.00014 22.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Acyl-CoA_dh_1 PF00441.24 GAP89298.1 - 6.3e-30 104.4 3.9 2.5e-29 102.4 3.9 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAP89298.1 - 6e-20 72.0 0.2 3.1e-19 69.7 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 GAP89298.1 - 1.3e-19 70.2 0.0 2.5e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAP89298.1 - 1.2e-10 41.8 7.1 1.2e-10 41.8 7.1 3.1 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain CoA_transf_3 PF02515.17 GAP89299.1 - 1e-111 373.6 0.2 1.2e-111 373.4 0.2 1.1 1 0 0 1 1 1 1 CoA-transferase family III SNF2_N PF00176.23 GAP89300.1 - 3e-73 246.5 0.9 3e-73 246.5 0.9 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP89300.1 - 6.1e-22 78.1 1.2 1.4e-18 67.3 0.0 4.2 4 1 1 5 5 5 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 GAP89300.1 - 4.4e-20 71.5 0.1 1.1e-19 70.2 0.1 1.7 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 GAP89300.1 - 2.4e-18 66.2 13.2 2.4e-18 66.2 13.2 5.4 5 1 0 5 5 5 1 HSA SnAC PF14619.6 GAP89300.1 - 1.3e-13 51.3 1.5 1.3e-13 51.3 1.5 3.7 3 1 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 GAP89300.1 - 1.9e-10 40.3 2.9 1.9e-10 40.3 2.9 2.4 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 GAP89300.1 - 3.3e-10 40.2 0.0 3.3e-10 40.2 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RBR PF17208.3 GAP89300.1 - 0.0087 16.7 7.6 0.0087 16.7 7.6 2.7 3 0 0 3 3 3 1 RNA binding Region Paramyxo_NS_C PF02725.14 GAP89300.1 - 0.28 11.3 3.0 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 Non-structural protein C WD40 PF00400.32 GAP89301.1 - 7e-13 48.8 10.0 0.0046 17.8 1.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP89301.1 - 0.00018 21.8 0.0 1.1 9.7 0.0 4.1 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain MraZ PF02381.18 GAP89301.1 - 0.12 12.4 0.0 28 4.8 0.0 2.5 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like Nup160 PF11715.8 GAP89301.1 - 0.18 10.4 0.7 0.47 9.0 0.2 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Cwf_Cwc_15 PF04889.12 GAP89301.1 - 3.6 7.2 11.2 0.34 10.6 6.6 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mg_trans_NIPA PF05653.14 GAP89302.1 - 8.8e-59 199.0 6.8 6.7e-56 189.6 4.5 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 GAP89302.1 - 0.024 14.8 2.6 0.024 14.8 2.6 3.9 3 1 1 4 4 4 0 EamA-like transporter family Prothymosin PF03247.14 GAP89302.1 - 0.11 13.0 1.7 0.2 12.1 1.7 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF1461 PF07314.11 GAP89302.1 - 0.86 9.5 3.6 0.41 10.5 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) TssN PF17555.2 GAP89302.1 - 2.9 7.2 6.3 4.8 6.5 6.3 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN HLH PF00010.26 GAP89303.1 - 1.4e-13 50.6 0.0 2.7e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MerR-DNA-bind PF09278.11 GAP89303.1 - 0.035 14.6 2.1 0.074 13.6 2.1 1.5 1 0 0 1 1 1 0 MerR, DNA binding MFAP1 PF06991.11 GAP89303.1 - 0.073 12.9 4.4 0.11 12.3 4.4 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing bZIP_1 PF00170.21 GAP89303.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor SLX9 PF15341.6 GAP89303.1 - 5.2 7.5 9.7 0.98 9.8 4.9 2.1 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 PBD PF00786.28 GAP89306.1 - 0.019 15.3 0.5 0.44 10.9 0.0 2.6 2 0 0 2 2 2 0 P21-Rho-binding domain S1 PF00575.23 GAP89307.1 - 5.8e-77 254.0 40.2 1.3e-12 47.9 0.6 12.9 13 0 0 13 13 13 10 S1 RNA binding domain TPR_14 PF13428.6 GAP89307.1 - 6.4e-07 29.7 2.2 0.82 10.7 0.6 5.1 1 1 4 5 5 5 2 Tetratricopeptide repeat Suf PF05843.14 GAP89307.1 - 1.8e-06 28.1 12.2 6.6e-05 23.0 0.2 4.2 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 GAP89307.1 - 2.1e-06 28.1 3.6 0.5 10.9 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat NRDE-2 PF08424.10 GAP89307.1 - 0.0018 17.4 1.8 0.057 12.5 0.2 2.9 1 1 2 3 3 3 1 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 GAP89307.1 - 0.0042 17.6 0.1 24 5.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAP89307.1 - 0.0043 17.7 4.0 0.0079 16.8 0.3 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAP89307.1 - 0.019 15.3 0.1 16 6.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PCB_OB PF17092.5 GAP89307.1 - 0.047 14.4 16.8 7.9 7.3 0.1 8.4 9 1 0 9 9 9 0 Penicillin-binding protein OB-like domain S1_2 PF13509.6 GAP89307.1 - 0.13 12.3 6.2 80 3.4 0.0 6.2 8 0 0 8 8 7 0 S1 domain PAS_11 PF14598.6 GAP89307.1 - 0.14 12.3 1.2 0.54 10.4 0.0 2.6 4 0 0 4 4 4 0 PAS domain TPR_2 PF07719.17 GAP89307.1 - 0.35 11.1 1.0 19 5.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 GAP89307.1 - 7.5 6.6 8.6 7.5 6.6 0.1 4.9 7 0 0 7 7 7 0 RNase II-type exonuclease C-terminal S1 domain Fmp27 PF10344.9 GAP89309.1 - 1.5e-220 734.7 0.0 2.5e-220 734.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 GAP89309.1 - 1.8e-192 640.5 2.4 1.8e-192 640.5 2.4 3.2 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 GAP89309.1 - 3.7e-182 606.5 5.2 3.7e-182 606.5 5.2 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 GAP89309.1 - 5.8e-57 192.2 0.0 1.3e-56 191.1 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 GAP89309.1 - 2.5e-53 180.2 0.2 6.8e-53 178.7 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 GAP89309.1 - 1.1e-35 122.4 0.0 6.9e-35 119.9 0.0 2.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Serine_rich PF08824.10 GAP89309.1 - 0.0091 16.0 0.3 0.0091 16.0 0.3 2.3 3 0 0 3 3 3 1 Serine rich protein interaction domain CheZ PF04344.13 GAP89309.1 - 0.037 13.9 0.1 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ EAP30 PF04157.16 GAP89310.1 - 8.4e-51 172.5 0.0 9.4e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_S9 PF00380.19 GAP89311.1 - 6.3e-33 113.9 0.2 7.1e-33 113.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF3362 PF11842.8 GAP89311.1 - 0.062 13.6 0.0 0.085 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) AAR2 PF05282.11 GAP89312.1 - 3.5e-52 178.0 0.0 4.5e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein Glyco_hydro_61 PF03443.14 GAP89314.1 - 2.1e-56 191.1 0.3 2.6e-56 190.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DEAD PF00270.29 GAP89315.1 - 1.5e-49 168.2 0.0 1.2e-48 165.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP89315.1 - 4.1e-31 107.6 0.1 1.3e-30 106.0 0.0 1.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP89315.1 - 5.4e-05 23.3 0.0 0.00016 21.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 GAP89315.1 - 0.0028 16.5 0.0 0.48 9.1 0.0 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 GAP89315.1 - 0.016 15.5 0.0 4.3 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 GAP89315.1 - 0.026 13.7 0.1 0.037 13.2 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_2 PF13307.6 GAP89315.1 - 0.036 14.2 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain DUF5335 PF17269.2 GAP89315.1 - 0.05 13.4 0.1 0.09 12.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) POTRA_2 PF08479.11 GAP89315.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 POTRA domain, ShlB-type Phos_pyr_kin PF08543.12 GAP89316.1 - 1.5e-88 296.3 0.3 2.1e-88 295.9 0.3 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 GAP89316.1 - 7.1e-50 169.7 0.1 1.2e-49 169.0 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 GAP89316.1 - 7.7e-08 32.0 0.1 1.8e-07 30.7 0.1 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 GAP89316.1 - 0.088 12.2 2.4 1.3 8.4 2.4 2.4 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 GAP89316.1 - 0.12 11.9 1.9 0.6 9.5 1.9 2.2 1 1 0 1 1 1 0 Carbohydrate kinase RICTOR_N PF14664.6 GAP89317.1 - 2.3e-132 441.5 0.2 8.5e-132 439.6 0.0 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 GAP89317.1 - 3.7e-40 135.9 0.2 1.4e-36 124.4 0.0 4.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 GAP89317.1 - 1.7e-38 131.3 0.7 6.9e-35 119.7 0.0 4.5 6 0 0 6 6 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 GAP89317.1 - 3.5e-30 104.1 0.1 2.1e-28 98.3 0.0 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 GAP89317.1 - 8e-15 54.7 9.0 1.8e-14 53.6 9.0 1.7 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.6 GAP89317.1 - 0.15 12.3 9.6 0.23 11.6 8.1 2.1 2 0 0 2 2 2 0 Up-regulated During Septation DUF4558 PF15104.6 GAP89317.1 - 0.34 11.0 5.1 0.74 9.9 5.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) THOC7 PF05615.13 GAP89317.1 - 0.41 10.9 8.4 0.98 9.7 8.4 1.6 1 0 0 1 1 1 0 Tho complex subunit 7 DUF724 PF05266.14 GAP89317.1 - 1.7 8.4 5.3 3.7 7.3 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2203 PF09969.9 GAP89317.1 - 2.9 8.7 6.6 7.6 7.3 6.6 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) UPF0242 PF06785.11 GAP89317.1 - 6.8 6.8 8.2 13 5.8 8.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_1 PF00515.28 GAP89318.1 - 3.9e-16 58.1 3.5 2e-08 33.7 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAP89318.1 - 3e-15 55.0 4.6 2.1e-06 27.4 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAP89318.1 - 1.3e-11 44.6 0.2 2.8e-07 30.7 0.1 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP89318.1 - 6.5e-11 41.6 0.6 8.1e-06 25.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP89318.1 - 4.9e-08 33.1 0.2 0.088 13.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP89318.1 - 6.4e-08 32.1 0.5 1.1e-05 25.1 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAP89318.1 - 2.7e-07 30.2 1.7 1.5e-05 24.5 0.1 3.6 2 1 1 3 3 3 1 TPR repeat PB1 PF00564.24 GAP89318.1 - 8.1e-06 25.7 0.5 1.4e-05 25.0 0.5 1.4 1 0 0 1 1 1 1 PB1 domain TPR_9 PF13371.6 GAP89318.1 - 1.6e-05 24.9 0.0 0.087 13.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAP89318.1 - 9.6e-05 22.5 0.0 0.22 12.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAP89318.1 - 0.00015 22.3 0.1 0.0028 18.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAP89318.1 - 0.0078 16.1 1.2 0.2 11.6 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAP89318.1 - 0.012 16.3 0.2 0.22 12.5 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAP89318.1 - 0.032 14.8 0.2 47 5.0 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat GRP PF07172.11 GAP89318.1 - 0.093 13.4 10.5 0.21 12.3 10.5 1.6 1 0 0 1 1 1 0 Glycine rich protein family HMA PF00403.26 GAP89319.1 - 4e-14 52.8 0.2 7e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 GAP89319.1 - 2.9e-07 30.7 0.0 4.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L13 PF00572.18 GAP89320.1 - 2.3e-40 137.7 0.0 3.4e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 GAP89321.1 - 1.4e-76 255.1 0.1 1.2e-40 138.8 0.2 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 GAP89321.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Plasmid recombination enzyme Polysacc_deac_1 PF01522.21 GAP89322.1 - 2.4e-28 98.5 0.1 3.7e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 GAP89322.1 - 5e-05 23.7 44.2 0.00012 22.4 20.1 5.9 5 1 1 6 6 6 3 Chitin recognition protein DLIC PF05783.11 GAP89322.1 - 9.3 4.9 5.2 14 4.4 5.2 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) SR-25 PF10500.9 GAP89324.1 - 0.42 10.2 7.5 0.68 9.5 7.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DEDD_Tnp_IS110 PF01548.17 GAP89325.1 - 0.086 12.7 0.1 8.6 6.2 0.0 2.6 3 0 0 3 3 3 0 Transposase Sen15 PF09631.10 GAP89325.1 - 0.14 12.5 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 Sen15 protein Dioxygenase_C PF00775.21 GAP89326.1 - 1.5e-40 138.6 0.0 2.6e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 GAP89326.1 - 4.4e-28 96.9 0.0 8.9e-28 96.0 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 GAP89326.1 - 0.002 18.3 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4646 PF15496.6 GAP89326.1 - 0.16 12.6 0.0 0.25 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) DUF3336 PF11815.8 GAP89327.1 - 9.9e-49 164.6 1.5 1.7e-48 163.9 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAP89327.1 - 1.5e-17 64.4 0.4 8.4e-17 62.0 0.1 2.3 2 1 0 2 2 2 1 Patatin-like phospholipase FAM83 PF07894.12 GAP89327.1 - 0.048 13.2 0.3 0.098 12.2 0.3 1.4 1 0 0 1 1 1 0 FAM83 A-H DUF1765 PF08578.10 GAP89327.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) Arf PF00025.21 GAP89328.1 - 1.1e-65 220.4 0.0 1.2e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 GAP89328.1 - 1.5e-12 47.4 0.0 5.9e-09 35.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GAP89328.1 - 2.6e-08 33.5 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 GAP89328.1 - 7.5e-08 32.6 0.0 2.5e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAP89328.1 - 1.8e-07 31.2 0.0 2.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 GAP89328.1 - 1e-06 28.4 0.0 1.4e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAP89328.1 - 1.2e-05 24.8 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 GAP89328.1 - 0.0067 16.0 0.1 0.26 10.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 GAP89328.1 - 0.13 11.9 0.0 6.4 6.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2457 PF10446.9 GAP89329.1 - 4.1e-157 524.1 25.8 4.1e-157 524.1 25.8 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) TFIIA PF03153.13 GAP89329.1 - 2.7 7.9 16.6 0.37 10.7 12.1 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ATP-synt_DE_N PF02823.16 GAP89330.1 - 6.2e-18 64.5 0.0 9.4e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain MAGUK_N_PEST PF10608.9 GAP89331.1 - 7.5 7.0 10.3 0.12 12.9 0.8 2.8 2 1 1 3 3 3 0 Polyubiquitination (PEST) N-terminal domain of MAGUK PalH PF08733.10 GAP89333.1 - 2.6e-107 358.6 0.1 3.1e-107 358.4 0.1 1.0 1 0 0 1 1 1 1 PalH/RIM21 TRAM_LAG1_CLN8 PF03798.16 GAP89334.1 - 2.9e-35 121.8 23.5 2.9e-35 121.8 23.5 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 GAP89334.1 - 2.6e-26 91.1 0.0 8.2e-26 89.5 0.0 1.9 1 0 0 1 1 1 1 TRAM1-like protein Ninjurin PF04923.12 GAP89334.1 - 0.13 12.2 0.1 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 Ninjurin ABC_membrane PF00664.23 GAP89335.1 - 3.5e-34 118.7 7.4 8.9e-34 117.4 7.4 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAP89335.1 - 2.4e-32 112.3 0.0 5.9e-32 111.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 GAP89335.1 - 3.8e-06 26.5 1.3 8.4e-05 22.1 0.5 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 GAP89335.1 - 0.0012 18.8 0.0 0.0036 17.2 0.0 1.8 1 1 1 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 GAP89335.1 - 0.011 16.0 0.3 0.5 10.6 0.2 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 GAP89335.1 - 0.018 14.8 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 GAP89335.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2786 PF10979.8 GAP89335.1 - 1.8 8.5 5.1 4.1 7.4 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) FSA_C PF10479.9 GAP89336.1 - 5.3 5.0 7.5 6.4 4.8 7.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AAA PF00004.29 GAP89337.1 - 3.1e-98 325.3 0.0 1.2e-47 161.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAP89337.1 - 3.8e-25 87.4 1.6 9.9e-13 47.7 0.4 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 GAP89337.1 - 3.9e-19 68.6 0.4 1.5e-18 66.7 0.4 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 GAP89337.1 - 3.4e-14 52.9 0.0 6e-06 26.1 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAP89337.1 - 1.4e-13 51.3 0.0 3.1e-07 30.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAP89337.1 - 2e-13 51.0 0.0 0.00018 21.9 0.0 4.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 GAP89337.1 - 4e-12 46.3 0.3 3.5e-06 27.0 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 GAP89337.1 - 6.7e-12 45.8 0.0 3.9e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 GAP89337.1 - 1.8e-09 38.0 0.4 0.028 14.7 0.0 4.1 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 GAP89337.1 - 3.5e-09 36.4 0.0 0.0013 18.0 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain Vps4_C PF09336.10 GAP89337.1 - 1.9e-07 31.0 0.2 2e-06 27.7 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 GAP89337.1 - 2e-07 31.6 0.0 0.029 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 GAP89337.1 - 2e-07 30.6 0.2 0.0069 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.17 GAP89337.1 - 3.1e-07 30.1 0.0 7.8e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 GAP89337.1 - 3.5e-07 30.1 0.0 0.02 14.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 GAP89337.1 - 5e-07 29.8 0.0 0.0076 16.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 GAP89337.1 - 5.7e-07 29.9 0.0 0.031 14.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase ATPase PF06745.13 GAP89337.1 - 1.1e-06 28.1 0.3 0.25 10.6 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 GAP89337.1 - 1.3e-06 28.1 4.6 0.23 11.0 0.1 4.8 3 2 2 5 5 5 2 AAA domain AAA_7 PF12775.7 GAP89337.1 - 2e-06 27.4 0.0 0.037 13.6 0.0 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 GAP89337.1 - 4.3e-06 26.6 0.0 0.082 12.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 GAP89337.1 - 8.6e-06 25.0 0.1 0.052 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 GAP89337.1 - 1.1e-05 24.8 0.0 0.03 13.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_28 PF13521.6 GAP89337.1 - 1.9e-05 25.0 0.0 0.18 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 GAP89337.1 - 2.5e-05 24.0 0.0 0.25 11.0 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 GAP89337.1 - 3.1e-05 24.5 0.0 0.28 11.7 0.0 3.4 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.18 GAP89337.1 - 3.7e-05 23.7 0.0 0.22 11.3 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein TsaE PF02367.17 GAP89337.1 - 7.3e-05 22.8 0.0 0.48 10.4 0.0 2.6 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 GAP89337.1 - 0.00013 21.9 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain ResIII PF04851.15 GAP89337.1 - 0.00016 21.7 0.0 0.044 13.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 GAP89337.1 - 0.00024 20.6 0.3 0.68 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 GAP89337.1 - 0.00024 20.9 0.0 0.7 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 GAP89337.1 - 0.00025 21.5 0.0 0.59 10.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 GAP89337.1 - 0.00039 20.3 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAP89337.1 - 0.00048 19.9 0.3 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 GAP89337.1 - 0.00071 19.6 0.0 2.1 8.2 0.0 3.4 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 GAP89337.1 - 0.0016 18.8 0.8 5.9 7.2 0.0 3.5 3 1 1 4 4 3 0 AAA domain DUF2075 PF09848.9 GAP89337.1 - 0.0021 17.4 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 GAP89337.1 - 0.004 17.3 0.0 0.55 10.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 GAP89337.1 - 0.005 16.1 0.0 1.4 8.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 GAP89337.1 - 0.0077 16.1 0.7 2.5 8.0 0.0 3.7 4 0 0 4 4 3 1 NTPase Viral_helicase1 PF01443.18 GAP89337.1 - 0.0082 15.9 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.16 GAP89337.1 - 0.013 14.9 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.14 GAP89337.1 - 0.014 14.7 0.5 1.1 8.4 0.0 3.2 2 2 1 4 4 4 0 KAP family P-loop domain Zeta_toxin PF06414.12 GAP89337.1 - 0.019 14.2 0.2 7.9 5.7 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin UFD1 PF03152.14 GAP89337.1 - 0.026 14.0 0.0 0.16 11.4 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 AAA_6 PF12774.7 GAP89337.1 - 0.045 12.7 0.1 7.6 5.4 0.0 2.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 GAP89337.1 - 0.056 13.2 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 GAP89337.1 - 0.07 12.8 0.0 3 7.5 0.0 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin2 PF13189.6 GAP89337.1 - 0.07 13.2 0.0 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family AFG1_ATPase PF03969.16 GAP89337.1 - 0.1 11.5 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AMP-binding PF00501.28 GAP89338.1 - 3.1e-78 263.3 0.0 4.7e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP89338.1 - 0.0046 17.9 0.0 0.015 16.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 GAP89339.1 - 3.3e-65 219.9 1.4 3.8e-65 219.7 1.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAP89339.1 - 8e-31 107.8 1.9 1.2e-29 103.9 0.5 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Se-cys_synth_N PF12390.8 GAP89339.1 - 0.083 13.1 1.8 0.25 11.6 0.6 2.4 2 0 0 2 2 2 0 Selenocysteine synthase N terminal Peptidase_S49 PF01343.18 GAP89339.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase family S49 Aa_trans PF01490.18 GAP89340.1 - 4.5e-59 200.2 31.8 5.5e-59 199.9 31.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein fn3_3 PF14686.6 GAP89341.1 - 2.2e-21 75.4 0.0 6.2e-21 74.0 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 GAP89341.1 - 6.6e-17 61.9 0.0 1.1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III TPR_17 PF13431.6 GAP89343.1 - 0.0016 18.7 0.3 0.16 12.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAP89343.1 - 0.0053 17.0 2.6 4.7 7.6 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat FMN_bind_2 PF04299.12 GAP89345.1 - 6.4e-56 188.7 0.0 8.2e-56 188.3 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Protoglobin PF11563.8 GAP89347.1 - 3.5e-54 183.0 0.0 4.6e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Lipase_GDSL_2 PF13472.6 GAP89348.1 - 0.064 13.7 0.5 0.13 12.7 0.3 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF1445 PF07286.12 GAP89349.1 - 6.9e-25 87.7 0.1 7.4e-25 87.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Fungal_trans PF04082.18 GAP89351.1 - 3.4e-31 108.3 0.0 6.2e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP89351.1 - 2.8e-08 33.7 14.9 4.6e-08 33.1 14.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 GAP89352.1 - 4.7e-08 32.8 7.0 7.9e-08 32.1 7.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAP89352.1 - 0.03 13.9 4.0 0.052 13.1 4.0 1.3 1 0 0 1 1 1 0 PHD-finger Iso_dh PF00180.20 GAP89353.1 - 1.8e-123 412.1 0.0 2.1e-123 411.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TauD PF02668.16 GAP89354.1 - 3.6e-54 184.4 0.4 4.5e-54 184.0 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Acetyltransf_1 PF00583.25 GAP89355.1 - 1.5e-11 44.6 0.0 2.5e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP89355.1 - 5.3e-10 39.6 0.0 9.9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAP89355.1 - 3e-07 30.4 0.0 5.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP89355.1 - 0.00064 19.8 0.0 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAP89355.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 GAP89355.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein DUF4451 PF14616.6 GAP89356.1 - 5.7e-24 84.7 0.0 9.9e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) CorA PF01544.18 GAP89358.1 - 6.8e-13 48.6 0.1 1.1e-12 48.0 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TPR_12 PF13424.6 GAP89361.1 - 3.2e-12 46.5 7.8 0.00037 20.7 1.8 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 GAP89361.1 - 4e-11 42.6 0.0 8.2e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 GAP89361.1 - 1.7e-08 33.9 11.4 0.0041 17.1 0.3 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAP89361.1 - 1.6e-06 27.7 13.1 0.12 12.2 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 GAP89361.1 - 1.2e-05 26.1 0.1 2.8e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_10 PF13374.6 GAP89361.1 - 0.00013 21.7 1.4 18 5.3 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAP89361.1 - 0.00035 21.2 4.8 0.13 13.2 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Hydrolase_4 PF12146.8 GAP89361.1 - 0.002 17.4 0.0 0.0057 15.9 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 TPR_8 PF13181.6 GAP89361.1 - 0.0024 17.9 10.1 30 5.2 0.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAP89361.1 - 0.0046 17.4 2.5 3.4 8.3 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF676 PF05057.14 GAP89361.1 - 0.005 16.4 0.0 0.0097 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_7 PF13176.6 GAP89361.1 - 0.041 13.9 2.2 14 5.9 0.1 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF900 PF05990.12 GAP89361.1 - 0.065 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 GAP89361.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein MIT PF04212.18 GAP89361.1 - 0.67 10.1 7.5 1.2 9.3 2.0 3.1 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 GAP89361.1 - 1.3 9.8 3.8 1.3e+02 3.7 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Actin PF00022.19 GAP89362.1 - 6.3e-30 104.1 0.0 8.8e-19 67.4 0.0 2.8 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 GAP89362.1 - 1.1e-05 24.8 0.3 0.049 12.8 0.1 2.3 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 GAP89362.1 - 0.0039 16.1 0.0 0.017 13.9 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 GAP89362.1 - 0.014 15.8 0.0 0.055 13.9 0.0 2.1 2 1 0 2 2 2 0 Cell division protein FtsA DUF2070 PF09843.9 GAP89362.1 - 9 4.5 6.4 18 3.4 4.5 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) SNF2_N PF00176.23 GAP89363.1 - 2.6e-42 144.8 0.1 4.9e-42 143.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP89363.1 - 3.8e-20 72.3 0.0 1.2e-19 70.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP89363.1 - 9.4e-07 29.0 0.0 4.1e-06 26.9 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAP89363.1 - 6.8e-05 22.6 0.3 0.14 11.8 0.0 2.8 2 0 0 2 2 2 2 SWI2/SNF2 ATPase SAM_1 PF00536.30 GAP89363.1 - 0.0016 18.8 0.2 0.028 14.9 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 GAP89363.1 - 0.1 12.7 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GSH_synth_ATP PF03917.17 GAP89364.1 - 2.7e-134 447.7 0.0 3e-134 447.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 GAP89364.1 - 1.4e-30 105.8 0.0 2.2e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase FANCM-MHF_bd PF16783.5 GAP89364.1 - 0.018 15.1 0.0 0.044 13.9 0.0 1.7 2 0 0 2 2 2 0 FANCM to MHF binding domain SET PF00856.28 GAP89366.1 - 6.4e-10 39.7 0.0 1.6e-09 38.4 0.0 1.7 1 1 0 1 1 1 1 SET domain zf-C6H2 PF15801.5 GAP89366.1 - 0.029 14.7 4.2 0.043 14.1 2.4 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding CsbD PF05532.12 GAP89367.1 - 0.00024 20.9 7.7 0.008 16.1 1.9 2.3 2 1 0 2 2 2 2 CsbD-like BCNT PF07572.12 GAP89368.1 - 1.4e-25 89.2 3.3 1.4e-25 89.2 3.3 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development Pro_isomerase PF00160.21 GAP89369.1 - 3.6e-49 167.1 0.2 6.8e-49 166.2 0.2 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 GAP89369.1 - 6.8e-06 26.2 0.0 2.5e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 GAP89369.1 - 0.0002 21.4 0.0 0.00055 20.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 GAP89369.1 - 0.0017 17.8 0.4 0.01 15.2 0.4 2.1 1 1 0 1 1 1 1 Rtf2 RING-finger Lung_7-TM_R PF06814.13 GAP89370.1 - 3.5e-72 243.2 11.5 4.2e-72 242.9 11.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Methyltransf_28 PF02636.17 GAP89371.1 - 4.6e-82 275.6 0.0 5.7e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 GAP89372.1 - 4.9e-62 209.7 0.0 7.6e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89372.1 - 1.3e-29 103.2 0.0 2.5e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP89372.1 - 0.0013 18.1 0.0 0.003 16.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAP89372.1 - 0.0028 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MAP7 PF05672.11 GAP89372.1 - 0.044 13.5 16.5 0.077 12.7 16.5 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Haspin_kinase PF12330.8 GAP89372.1 - 0.093 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 GAP89372.1 - 0.23 11.4 4.5 0.75 9.7 4.5 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family LCD1 PF09798.9 GAP89372.1 - 0.48 8.9 2.8 0.61 8.5 2.8 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Rotamase PF00639.21 GAP89372.1 - 1.2 10.2 6.7 2.8 9.0 6.7 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain Raftlin PF15250.6 GAP89372.1 - 2.8 6.6 6.8 3.9 6.1 6.8 1.1 1 0 0 1 1 1 0 Raftlin DUF4407 PF14362.6 GAP89372.1 - 4.1 6.7 7.6 5.5 6.2 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rrn6 PF10214.9 GAP89372.1 - 6.5 5.1 6.7 8.9 4.7 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SpoIIIAH PF12685.7 GAP89373.1 - 0.025 14.4 1.8 0.028 14.3 1.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein MGC-24 PF05283.11 GAP89373.1 - 3.4 8.1 11.8 0.72 10.3 7.7 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CENP-F_N PF10481.9 GAP89373.1 - 6.7 6.2 6.3 11 5.6 6.3 1.2 1 0 0 1 1 1 0 Cenp-F N-terminal domain Glyco_hydro_61 PF03443.14 GAP89374.1 - 7.6e-20 71.7 0.0 9.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_cc PF11790.8 GAP89376.1 - 2.6e-35 122.1 0.1 3.7e-35 121.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core CAP PF00188.26 GAP89376.1 - 1.2e-19 71.4 1.4 3.6e-19 69.8 1.4 1.8 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Octopine_DH PF02317.17 GAP89379.1 - 5.5e-38 130.4 0.0 9.4e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NmrA PF05368.13 GAP89379.1 - 2.3e-14 53.5 0.0 6.7e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 GAP89379.1 - 2.3e-11 43.9 0.0 4.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 GAP89379.1 - 4e-09 36.9 0.4 7e-06 26.5 0.1 2.9 2 1 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 GAP89379.1 - 5e-09 36.0 0.1 2.7e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 GAP89379.1 - 4.6e-08 33.2 0.2 2e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 GAP89379.1 - 1.2e-05 25.5 0.1 0.0003 21.1 0.0 2.6 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain CoA_binding PF02629.19 GAP89379.1 - 0.0059 17.3 1.8 0.25 12.1 0.1 3.1 2 1 0 2 2 2 1 CoA binding domain Pyr_redox_2 PF07992.14 GAP89379.1 - 0.01 15.1 0.1 0.036 13.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP89379.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 GAP89379.1 - 0.024 14.8 0.1 0.078 13.2 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Epimerase PF01370.21 GAP89379.1 - 0.025 14.1 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family IlvN PF07991.12 GAP89379.1 - 0.033 13.8 0.7 0.25 10.9 0.1 2.5 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 GAP89379.1 - 0.034 14.3 0.0 0.54 10.4 0.0 2.4 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 GAP89379.1 - 0.062 13.2 0.3 12 5.8 0.0 3.0 3 0 0 3 3 3 0 Rossmann-like domain FAD_binding_3 PF01494.19 GAP89379.1 - 0.14 11.4 1.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 GAP89379.1 - 0.19 11.3 0.0 0.48 10.0 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Exo_endo_phos PF03372.23 GAP89380.1 - 4e-09 36.3 0.4 1.6e-08 34.4 0.4 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3445 PF11927.8 GAP89381.1 - 6.5e-54 182.9 0.0 8.6e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3445 PF11927.8 GAP89382.1 - 2.1e-10 40.7 0.3 2.9e-10 40.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF829 PF05705.14 GAP89383.1 - 3e-34 119.0 0.0 4.6e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.16 GAP89384.1 - 2.2e-27 95.9 50.2 3.3e-25 88.8 50.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP89384.1 - 6.2e-05 21.6 20.0 0.00011 20.7 17.1 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 GAP89385.1 - 2.4e-32 112.3 0.0 1.3e-18 67.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF4128 PF13554.6 GAP89385.1 - 0.2 11.7 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function Oxidored_molyb PF00174.19 GAP89386.1 - 7.5e-43 146.1 0.0 1.5e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAP89386.1 - 5e-18 65.4 0.4 1.2e-17 64.2 0.4 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Isochorismatase PF00857.20 GAP89387.1 - 1.6e-15 57.7 0.0 2e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DrsE_2 PF13686.6 GAP89387.1 - 0.02 14.8 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family Glyco_hydro_43 PF04616.14 GAP89390.1 - 1.4e-98 329.8 0.0 2e-98 329.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAP89390.1 - 1.5e-39 135.9 0.0 2.1e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Peptidase_A4 PF01828.17 GAP89391.1 - 2e-75 252.9 11.0 2.4e-75 252.6 11.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family TANGO2 PF05742.12 GAP89392.1 - 8.2e-68 229.2 0.0 9.4e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Tfb2 PF03849.14 GAP89394.1 - 2.6e-130 434.6 0.0 3.1e-130 434.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 GAP89394.1 - 1.1e-19 70.6 0.6 2.1e-19 69.7 0.6 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 GAP89394.1 - 0.00025 21.2 0.0 0.00057 20.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Na_H_antiport_1 PF06965.12 GAP89394.1 - 0.047 12.5 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter 1 Cu_amine_oxid PF01179.20 GAP89395.1 - 1.2e-161 538.3 0.0 1.5e-161 538.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 GAP89395.1 - 3.2e-21 75.6 0.1 5.7e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 GAP89395.1 - 1.4e-13 50.8 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RdgC PF04381.12 GAP89395.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC DUF1996 PF09362.10 GAP89396.1 - 6e-78 262.0 4.3 6e-78 262.0 4.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Glyco_hydro_18 PF00704.28 GAP89399.1 - 1.7e-51 175.8 0.0 2.3e-51 175.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 GAP89399.1 - 3.1e-13 49.9 105.8 3.3e-07 30.7 19.2 6.1 6 1 0 6 6 6 4 Chitin recognition protein FMO-like PF00743.19 GAP89400.1 - 2e-15 56.2 0.0 2.3e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAP89400.1 - 1.4e-13 50.8 0.0 2.8e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP89400.1 - 4.8e-13 49.0 0.0 1.5e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP89400.1 - 6.7e-10 38.6 0.6 7.1e-08 32.0 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAP89400.1 - 1.3e-09 38.1 0.0 1.5e-07 31.6 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP89400.1 - 2.1e-05 24.3 6.6 0.00061 19.5 0.1 3.5 3 1 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 GAP89400.1 - 3.3e-05 24.3 0.1 0.017 15.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP89400.1 - 9.3e-05 21.8 2.1 0.00011 21.6 0.0 2.1 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.24 GAP89400.1 - 0.002 17.3 0.0 1.1 8.3 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 GAP89400.1 - 0.0043 16.0 0.1 0.61 8.9 0.0 2.4 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 GAP89400.1 - 0.007 16.4 3.4 1.5 8.8 0.1 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 GAP89400.1 - 0.0099 15.9 0.0 0.38 10.8 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 GAP89400.1 - 0.01 16.3 0.0 0.087 13.3 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 GAP89400.1 - 0.035 13.7 1.0 0.43 10.2 0.1 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 GAP89400.1 - 0.13 11.3 1.5 2.4 7.1 0.0 2.8 4 0 0 4 4 4 0 Lycopene cyclase protein Mqo PF06039.15 GAP89400.1 - 0.16 10.5 0.0 6.6 5.2 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NTP_transferase PF00483.23 GAP89401.1 - 3.9e-29 102.0 0.0 6.2e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 GAP89401.1 - 1.3e-08 34.2 2.4 7.3e-07 28.7 0.0 3.2 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 GAP89401.1 - 0.017 14.1 0.1 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 L-fucokinase Proteasome PF00227.26 GAP89402.1 - 5.7e-60 202.1 0.1 7e-60 201.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAP89402.1 - 2.9e-14 52.4 0.2 8.7e-13 47.7 0.1 2.5 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 GAP89402.1 - 0.018 15.2 0.3 0.051 13.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 GAP89402.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SPOC PF07744.13 GAP89403.1 - 1.2e-20 73.9 0.0 2.1e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 GAP89403.1 - 1.5e-14 54.5 1.7 2.7e-14 53.6 1.7 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 GAP89403.1 - 2.9e-09 36.7 8.2 5.5e-09 35.8 8.2 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 GAP89403.1 - 4 7.5 6.7 1.3 9.0 3.3 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 WD40_alt PF14077.6 GAP89404.1 - 0.0072 16.2 2.4 0.13 12.2 0.1 3.6 3 0 0 3 3 3 1 Alternative WD40 repeat motif DUF5082 PF16888.5 GAP89404.1 - 0.0074 16.6 0.2 0.0074 16.6 0.2 9.2 2 2 3 7 7 7 1 Domain of unknown function (DUF5082) CENP-F_leu_zip PF10473.9 GAP89404.1 - 5.3 7.1 96.8 0.68 10.0 6.6 8.3 1 1 6 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hydrolase PF00702.26 GAP89405.1 - 2.1e-09 38.0 0.0 1.6e-08 35.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAP89405.1 - 7.3e-09 35.9 0.0 1.9e-08 34.6 0.0 1.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP89405.1 - 1.5e-05 24.9 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like p450 PF00067.22 GAP89406.1 - 6.3e-71 239.5 0.0 7.8e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MatE PF01554.18 GAP89407.1 - 1.6e-56 190.4 32.1 8.1e-37 126.4 12.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAP89407.1 - 0.0022 18.1 9.7 0.0022 18.1 9.7 4.7 2 2 2 5 5 5 3 Polysaccharide biosynthesis C-terminal domain Como_SCP PF02248.16 GAP89407.1 - 0.013 15.0 0.5 0.027 14.1 0.5 1.4 1 0 0 1 1 1 0 Small coat protein HSP70 PF00012.20 GAP89408.1 - 7.6e-09 34.3 0.1 1.1e-05 23.8 0.0 2.9 3 0 0 3 3 3 2 Hsp70 protein FlgN PF05130.12 GAP89408.1 - 0.21 12.1 0.0 0.4 11.2 0.0 1.4 1 0 0 1 1 1 0 FlgN protein FlgN PF05130.12 GAP89409.1 - 0.09 13.3 0.4 0.18 12.3 0.4 1.4 1 0 0 1 1 1 0 FlgN protein S1-P1_nuclease PF02265.16 GAP89410.1 - 1.6e-51 175.6 0.0 1.9e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease FMO-like PF00743.19 GAP89411.1 - 4.8e-18 64.9 0.1 5e-15 54.9 0.2 3.1 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAP89411.1 - 4.5e-12 45.8 0.1 2.7e-08 33.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAP89411.1 - 7.3e-12 45.1 0.0 8.7e-10 38.3 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP89411.1 - 3.8e-10 39.5 0.0 1.9e-05 24.1 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP89411.1 - 4e-10 39.8 0.1 9.5e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP89411.1 - 1e-08 35.2 0.0 2.2e-07 30.8 0.0 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAP89411.1 - 1.3e-05 25.2 0.0 0.0092 16.0 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 GAP89411.1 - 0.00045 19.6 0.0 0.031 13.6 0.0 2.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 GAP89411.1 - 0.00059 19.1 0.0 0.0031 16.8 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAP89411.1 - 0.0031 16.6 0.0 0.0099 15.0 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 GAP89411.1 - 0.013 16.1 0.0 0.76 10.4 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP89411.1 - 0.038 12.7 0.1 0.42 9.2 0.1 2.4 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 GAP89411.1 - 0.048 13.7 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 GAP89411.1 - 0.062 12.4 0.0 6.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Asp PF00026.23 GAP89412.1 - 1.8e-68 231.3 5.2 2.2e-68 231.0 5.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP89412.1 - 2.6e-09 37.5 0.6 0.002 18.4 0.2 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAP89412.1 - 8.2e-05 23.2 3.6 0.028 15.1 1.1 3.3 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 GAP89412.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Glyco_hydro_18 PF00704.28 GAP89413.1 - 1.8e-85 287.4 8.3 2.1e-85 287.2 8.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NAD_binding_8 PF13450.6 GAP89416.1 - 7.9e-13 48.4 0.2 2.7e-12 46.7 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP89416.1 - 5.3e-10 39.4 0.0 1.6e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAP89416.1 - 2.2e-08 33.8 0.1 0.0052 16.1 0.0 3.2 3 1 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 GAP89416.1 - 4.5e-07 29.4 0.0 0.00017 20.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP89416.1 - 9.1e-05 21.3 0.0 0.022 13.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 GAP89416.1 - 0.00019 21.9 0.0 0.58 10.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP89416.1 - 0.00022 20.4 0.1 0.00037 19.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 GAP89416.1 - 0.00031 20.8 0.1 0.0033 17.4 0.0 2.5 2 1 1 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 GAP89416.1 - 0.0033 16.7 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 GAP89416.1 - 0.015 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAP89416.1 - 0.027 13.7 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 GAP89416.1 - 0.12 12.0 0.0 0.84 9.3 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 GAP89416.1 - 0.19 12.2 0.0 1.4 9.4 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Cyclin_N PF00134.23 GAP89417.1 - 1.9e-13 50.2 0.0 3.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 GAP89417.1 - 6.7e-08 33.1 0.1 6.7e-08 33.1 0.1 2.0 2 1 0 2 2 2 1 Cyclin Miga PF10265.9 GAP89417.1 - 0.12 11.3 3.0 0.17 10.8 3.0 1.1 1 0 0 1 1 1 0 Mitoguardin MAP65_ASE1 PF03999.12 GAP89417.1 - 0.61 8.7 6.7 0.84 8.3 6.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pkinase PF00069.25 GAP89418.1 - 1.6e-70 237.5 0.0 1.9e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89418.1 - 3.6e-31 108.4 0.0 4.6e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAP89418.1 - 0.00066 18.7 0.0 0.019 13.9 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 GAP89418.1 - 0.0049 16.2 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 GAP89418.1 - 0.006 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAP89418.1 - 0.021 13.9 0.1 0.039 13.0 0.1 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy_2 PF13532.6 GAP89419.1 - 1.1e-31 110.6 0.0 1.2e-31 110.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M20 PF01546.28 GAP89420.1 - 2.2e-29 102.6 0.2 3.4e-29 102.0 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Abhydrolase_6 PF12697.7 GAP89420.1 - 6.8e-15 56.3 0.8 6.8e-15 56.3 0.8 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family M20_dimer PF07687.14 GAP89420.1 - 3.2e-07 30.2 0.0 7.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Abhydrolase_5 PF12695.7 GAP89420.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M28 PF04389.17 GAP89420.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 RSN1_7TM PF02714.15 GAP89421.1 - 5.3e-59 199.8 22.3 3e-48 164.5 7.8 2.6 2 1 1 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAP89421.1 - 2.4e-41 141.1 1.0 2.4e-41 141.1 1.0 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 GAP89421.1 - 5.7e-22 77.7 1.2 1.3e-21 76.6 1.2 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 GAP89421.1 - 1.1e-19 71.4 0.0 1.8e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Syndecan PF01034.20 GAP89421.1 - 0.019 14.9 0.6 0.019 14.9 0.6 3.1 3 0 0 3 3 3 0 Syndecan domain Mucin15 PF15672.5 GAP89421.1 - 0.071 12.6 0.2 0.15 11.5 0.2 1.5 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 SPOR PF05036.13 GAP89421.1 - 0.085 13.2 0.3 0.25 11.8 0.1 1.9 2 0 0 2 2 2 0 Sporulation related domain EphA2_TM PF14575.6 GAP89421.1 - 0.6 11.0 4.4 4.7 8.2 0.0 3.8 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 GAP89421.1 - 0.8 9.7 2.7 0.61 10.0 0.6 1.8 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J GHMP_kinases_C PF08544.13 GAP89421.1 - 2.1 8.8 3.6 9.5 6.7 0.0 3.3 3 1 0 3 3 3 0 GHMP kinases C terminal TPR_MLP1_2 PF07926.12 GAP89422.1 - 3.8e-37 127.2 22.8 3.8e-37 127.2 22.8 18.6 9 4 8 17 17 17 4 TPR/MLP1/MLP2-like protein CALCOCO1 PF07888.11 GAP89422.1 - 0.00053 19.0 35.7 0.00053 19.0 35.7 10.7 4 2 5 11 11 11 3 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_5 PF07728.14 GAP89422.1 - 1 9.4 6.5 4 7.4 1.1 3.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sortilin-Vps10 PF15902.5 GAP89423.1 - 8.7e-13 47.9 10.2 0.00038 19.4 0.0 5.8 5 1 3 8 8 8 5 Sortilin, neurotensin receptor 3, BNR PF02012.20 GAP89423.1 - 3.4e-07 29.3 28.1 2.9 8.2 0.3 9.9 9 0 0 9 9 9 5 BNR/Asp-box repeat BNR_2 PF13088.6 GAP89423.1 - 0.1 11.9 17.7 0.5 9.6 0.8 5.5 2 2 2 5 5 5 0 BNR repeat-like domain BNR_6 PF15899.5 GAP89423.1 - 2.3 8.5 9.8 99 3.4 0.0 6.0 7 0 0 7 7 7 0 BNR-Asp box repeat TauD PF02668.16 GAP89424.1 - 2.7e-41 142.2 0.9 3.9e-40 138.4 0.9 2.0 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cwf_Cwc_15 PF04889.12 GAP89424.1 - 8.2 6.1 9.2 62 3.2 0.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2076 PF09849.9 GAP89425.1 - 0.23 11.5 10.5 0.33 11.0 10.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Sporozoite_P67 PF05642.11 GAP89425.1 - 0.27 9.3 5.5 0.24 9.5 5.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.11 GAP89425.1 - 1.6 6.9 2.8 1.8 6.7 2.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MSP1_C PF07462.11 GAP89425.1 - 9.3 4.8 9.4 12 4.5 9.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Glyco_transf_15 PF01793.16 GAP89427.1 - 3.8e-93 312.3 7.1 5.5e-93 311.8 7.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Hira PF07569.11 GAP89428.1 - 1.2e-87 293.3 0.0 2.7e-87 292.2 0.0 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 GAP89428.1 - 3.2e-32 110.0 19.3 1.1e-05 26.0 0.1 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP89428.1 - 1.7e-18 66.7 0.1 0.00081 19.6 0.0 6.1 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 GAP89428.1 - 2.5e-12 46.3 0.9 6.6e-12 45.0 0.9 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 GAP89428.1 - 3.7e-06 26.7 0.2 15 5.7 0.0 5.6 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 GAP89428.1 - 0.00014 20.9 0.6 0.85 8.5 0.0 4.5 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 GAP89428.1 - 0.12 10.3 0.1 0.51 8.2 0.0 2.0 3 0 0 3 3 3 0 IKI3 family DUF2400 PF09674.10 GAP89429.1 - 0.043 13.8 0.1 0.05 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) RPEL PF02755.15 GAP89431.1 - 1.3e-08 34.3 0.6 1.5e-05 24.5 0.4 2.5 2 0 0 2 2 2 2 RPEL repeat F-box PF00646.33 GAP89431.1 - 2.1e-07 30.7 0.1 4.4e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAP89431.1 - 1.8e-06 27.7 0.1 5e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 GAP89431.1 - 0.0089 15.9 0.0 0.0089 15.9 0.0 1.7 2 0 0 2 2 2 1 F-box Importin_rep_2 PF18786.1 GAP89431.1 - 0.041 13.7 0.3 0.081 12.8 0.3 1.4 1 0 0 1 1 1 0 Importin 13 repeat FlgN PF05130.12 GAP89432.1 - 0.049 14.1 7.6 0.11 13.0 7.6 1.5 1 0 0 1 1 1 0 FlgN protein zf-C2H2_jaz PF12171.8 GAP89432.1 - 0.22 11.9 0.1 0.46 10.8 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CENP-Q PF13094.6 GAP89432.1 - 2 8.6 13.6 0.34 11.1 8.7 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Med7 PF05983.11 GAP89433.1 - 2.3e-63 213.8 0.2 2.6e-63 213.6 0.2 1.0 1 0 0 1 1 1 1 MED7 protein SIMPL PF04402.14 GAP89433.1 - 0.0025 18.3 0.0 0.0031 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF4340 PF14238.6 GAP89433.1 - 0.065 13.3 0.1 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4340) DivIVA PF05103.13 GAP89436.1 - 0.013 15.5 0.1 0.016 15.3 0.1 1.1 1 0 0 1 1 1 0 DivIVA protein zf-ZPR1 PF03367.13 GAP89436.1 - 0.028 14.3 0.1 0.031 14.1 0.1 1.1 1 0 0 1 1 1 0 ZPR1 zinc-finger domain GLTP PF08718.11 GAP89436.1 - 0.04 14.2 0.0 0.042 14.1 0.0 1.1 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Pro-kuma_activ PF09286.11 GAP89437.1 - 1.4e-40 138.8 0.0 2.2e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 GAP89437.1 - 1.8e-05 24.2 0.0 4e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Subtilase family zf-C2H2 PF00096.26 GAP89438.1 - 4.3e-06 26.9 10.9 0.0029 18.0 0.1 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP89438.1 - 0.0074 17.0 0.2 0.0074 17.0 0.2 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP89438.1 - 0.043 14.1 0.1 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP89438.1 - 0.32 11.4 4.2 2.1 8.9 0.0 3.3 3 1 0 3 3 3 0 Zinc-finger of C2H2 type Homeobox_KN PF05920.11 GAP89439.1 - 0.0033 17.3 0.5 0.0072 16.2 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Zn_clus PF00172.18 GAP89439.1 - 0.023 14.8 7.5 0.043 13.9 7.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-SNAP50_C PF12251.8 GAP89439.1 - 0.53 9.9 4.1 0.82 9.3 2.8 1.7 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal DUF3716 PF12511.8 GAP89439.1 - 1.1 9.3 5.3 2.1 8.5 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) PALP PF00291.25 GAP89440.1 - 2.2e-60 204.6 0.3 4.6e-60 203.5 0.3 1.6 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 GAP89440.1 - 2.8e-29 102.3 0.9 9.7e-29 100.5 0.2 2.0 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAP89440.1 - 2.2e-15 56.5 0.0 7.8e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAP89440.1 - 7.3e-05 22.5 0.5 0.00017 21.4 0.5 1.6 2 0 0 2 2 2 1 Peptidase family M28 NAD_binding_1 PF00175.21 GAP89442.1 - 5.1e-28 97.9 0.0 8.5e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAP89442.1 - 1.9e-17 63.4 0.0 3.6e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAP89442.1 - 1.2e-06 28.7 0.0 0.0094 16.1 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Amidoligase_2 PF12224.8 GAP89443.1 - 3.3e-11 43.3 0.1 4.7e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Nuc_deoxyri_tr2 PF15891.5 GAP89444.1 - 2.3e-38 130.8 0.0 2.9e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 GAP89444.1 - 0.00089 19.3 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase TFIIA PF03153.13 GAP89445.1 - 0.012 15.6 17.3 0.013 15.5 10.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LUC7 PF03194.15 GAP89446.1 - 6.6e-66 222.5 0.1 8e-66 222.3 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus PLU-1 PF08429.11 GAP89446.1 - 0.0033 16.7 0.1 0.0042 16.3 0.1 1.1 1 0 0 1 1 1 1 PLU-1-like protein Spc7 PF08317.11 GAP89446.1 - 0.12 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Gpi16 PF04113.14 GAP89448.1 - 1.7e-234 779.5 0.0 2e-234 779.2 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component SRR1 PF07985.12 GAP89449.1 - 8.8e-07 28.9 0.0 2.2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 SRR1 HeLo PF14479.6 GAP89452.1 - 6.9e-42 143.6 0.0 8.6e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.8 GAP89452.1 - 0.00017 21.5 0.2 0.00032 20.7 0.2 1.4 1 0 0 1 1 1 1 Het-s 218-289 DUF3328 PF11807.8 GAP89453.1 - 1.1e-35 123.4 0.2 1.4e-35 123.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pro_Al_protease PF02983.14 GAP89454.1 - 4.1e-14 52.4 2.5 4.1e-14 52.4 2.5 2.4 3 0 0 3 3 3 1 Alpha-lytic protease prodomain DprA_WH PF17782.1 GAP89454.1 - 0.12 12.5 0.3 0.89 9.7 0.0 2.5 2 1 0 2 2 2 0 DprA winged helix domain Ribosomal_S24e PF01282.19 GAP89455.1 - 2.3e-21 75.5 0.0 3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e PDDEXK_7 PF04411.12 GAP89455.1 - 0.087 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF3394 PF11874.8 GAP89455.1 - 0.1 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) PhyH PF05721.13 GAP89456.1 - 1.2e-13 51.8 0.0 3.7e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.18 GAP89457.1 - 5.1e-21 74.9 0.0 7.8e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAP89458.1 - 5e-26 91.5 41.8 1.5e-25 89.9 40.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 GAP89458.1 - 0.00015 21.2 8.3 0.00015 21.2 8.3 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB UNC-93 PF05978.16 GAP89459.1 - 3.5e-10 39.8 6.8 1.5e-09 37.7 6.8 2.1 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 GAP89459.1 - 9.8e-09 34.6 41.5 1.1e-08 34.4 40.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily PNTB PF02233.16 GAP89459.1 - 0.051 12.5 1.2 0.11 11.4 1.2 1.6 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit LapA_dom PF06305.11 GAP89459.1 - 0.1 12.4 0.0 0.1 12.4 0.0 3.8 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain BcrAD_BadFG PF01869.20 GAP89460.1 - 3.1e-21 76.1 1.8 6.5e-21 75.0 0.7 2.0 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 GAP89460.1 - 2.5e-07 30.8 0.0 5.5e-06 26.4 0.0 3.1 2 1 0 2 2 2 1 SIS domain SIS PF01380.22 GAP89460.1 - 0.028 14.3 0.6 0.3 10.9 0.0 2.4 2 0 0 2 2 2 0 SIS domain Beta-lactamase PF00144.24 GAP89461.1 - 1.4e-51 175.7 0.3 2.1e-51 175.1 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase HET PF06985.11 GAP89462.1 - 1.8e-12 47.8 4.3 3.8e-10 40.3 0.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HRDC PF00570.23 GAP89463.1 - 0.0045 17.0 0.6 5 7.2 0.0 3.5 3 0 0 3 3 3 2 HRDC domain Pkinase PF00069.25 GAP89464.1 - 8.6e-41 140.0 0.2 1.3e-40 139.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89464.1 - 1.9e-19 70.0 0.1 2.7e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP89464.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 GAP89464.1 - 0.03 13.1 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FHA PF00498.26 GAP89464.1 - 0.03 14.7 2.0 0.068 13.5 0.4 2.3 2 0 0 2 2 2 0 FHA domain DUF2095 PF09868.9 GAP89464.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) IBR PF01485.21 GAP89465.1 - 6.3e-12 45.5 54.2 9.1e-08 32.2 9.4 4.5 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain FAD_binding_1 PF00667.20 GAP89466.1 - 9.3e-63 211.8 0.0 1.8e-62 210.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 GAP89466.1 - 3.4e-09 37.3 0.0 1.1e-08 35.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 GAP89466.1 - 4e-08 33.5 0.0 9.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 GAP89466.1 - 7e-07 29.5 0.1 1.9e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 GAP89466.1 - 0.097 12.6 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain Cupin_1 PF00190.22 GAP89467.1 - 3.1e-38 130.7 0.0 6e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 GAP89467.1 - 8.6e-21 73.4 1.1 3.9e-11 42.5 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 GAP89467.1 - 1.5e-05 24.6 0.0 0.053 13.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) 3-HAO PF06052.12 GAP89467.1 - 0.0028 17.3 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.7 GAP89467.1 - 0.087 12.5 0.0 5.1 6.8 0.0 2.8 2 1 1 3 3 3 0 Cupin Pkinase PF00069.25 GAP89468.1 - 7.9e-17 61.5 0.0 1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 GAP89468.1 - 1e-05 24.6 0.0 1.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 GAP89468.1 - 0.00081 18.8 0.0 0.00097 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP89468.1 - 0.0054 16.7 0.1 0.27 11.1 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family SAE2 PF08573.10 GAP89469.1 - 0.44 11.7 6.3 0.26 12.4 2.7 2.2 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Zn_clus PF00172.18 GAP89470.1 - 6.4e-07 29.4 13.4 1e-06 28.8 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dehydrin PF00257.19 GAP89470.1 - 1.5 9.3 3.4 2.3 8.7 0.3 2.3 2 0 0 2 2 2 0 Dehydrin Glyco_hydro_43 PF04616.14 GAP89472.1 - 1.4e-38 132.9 7.1 1.6e-38 132.7 7.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RCC1 PF00415.18 GAP89474.1 - 5.6e-56 187.0 5.1 3.7e-08 33.8 1.2 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAP89474.1 - 1e-32 111.2 29.4 4.6e-08 32.7 0.9 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat CDK5_activator PF03261.15 GAP89474.1 - 5.3 6.5 9.0 7.7 5.9 9.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Presenilin PF01080.17 GAP89474.1 - 8.3 5.1 6.7 11 4.6 6.7 1.2 1 0 0 1 1 1 0 Presenilin Beta-lactamase PF00144.24 GAP89475.1 - 9.6e-30 103.9 1.5 1.3e-27 96.9 0.0 3.2 2 2 0 2 2 2 1 Beta-lactamase ADH_N PF08240.12 GAP89477.1 - 7.5e-31 106.2 0.0 1.9e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP89477.1 - 3e-15 56.4 0.1 9e-15 54.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAP89477.1 - 2.8e-10 40.0 0.4 1.2e-09 38.0 0.4 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 GAP89477.1 - 1.5e-06 29.3 0.0 3.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAP89477.1 - 0.0092 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_16 PF10294.9 GAP89477.1 - 0.039 13.7 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase 2-Hacid_dh_C PF02826.19 GAP89477.1 - 0.044 13.1 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Patatin PF01734.22 GAP89478.1 - 6.8e-22 78.7 0.0 1.3e-21 77.8 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.27 GAP89478.1 - 0.00092 19.7 0.0 0.0024 18.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.7 GAP89478.1 - 0.003 16.5 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain RsgA_GTPase PF03193.16 GAP89478.1 - 0.0071 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 GAP89478.1 - 0.0082 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin zf-B_box PF00643.24 GAP89478.1 - 0.023 14.9 15.3 0.021 15.0 5.0 2.7 2 0 0 2 2 2 0 B-box zinc finger MMR_HSR1 PF01926.23 GAP89478.1 - 0.065 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 GAP89478.1 - 0.13 12.5 0.0 0.44 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain NUP PF06516.11 GAP89479.1 - 2.3e-105 352.3 0.0 2.6e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Glyco_hydro_43 PF04616.14 GAP89480.1 - 8.7e-40 136.8 0.9 9.9e-40 136.6 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Abhydrolase_6 PF12697.7 GAP89481.1 - 3.2e-16 60.6 0.0 3.8e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP89481.1 - 1.2e-06 28.0 0.0 8.7e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 GAP89481.1 - 0.11 12.3 0.2 0.58 9.9 0.1 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family Perilipin PF03036.16 GAP89482.1 - 0.15 11.0 0.0 0.32 10.0 0.0 1.5 1 0 0 1 1 1 0 Perilipin family Glyco_hydro_28 PF00295.17 GAP89484.1 - 1.3e-105 353.0 19.0 1.6e-105 352.8 19.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 GAP89484.1 - 0.035 13.4 8.0 0.061 12.6 8.0 1.4 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Sugar_tr PF00083.24 GAP89485.1 - 9.9e-99 331.2 15.5 1.6e-98 330.5 15.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP89485.1 - 1.7e-18 66.7 19.8 1.7e-18 66.7 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 GAP89485.1 - 0.15 12.3 2.8 0.93 9.8 2.8 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) PAP_assoc PF03828.19 GAP89487.1 - 2.8e-14 53.1 0.0 5.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 GAP89487.1 - 2.2e-07 31.1 0.0 4.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain SNF2_N PF00176.23 GAP89489.1 - 8.5e-12 44.4 0.0 1.3e-10 40.6 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 GAP89489.1 - 7.5e-10 38.7 0.0 1.3e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase Ureidogly_lyase PF04115.12 GAP89490.1 - 6.3e-55 185.9 0.0 7.6e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase Peptidase_C48 PF02902.19 GAP89491.1 - 4.2e-06 26.8 1.5 0.035 13.9 0.0 2.6 3 0 0 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain UbiA PF01040.18 GAP89492.1 - 1.5e-19 70.3 16.7 2.5e-19 69.6 13.9 1.9 1 1 1 2 2 2 1 UbiA prenyltransferase family Git3 PF11710.8 GAP89494.1 - 1.4e-09 38.1 6.4 6.5e-09 35.9 6.4 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 GAP89494.1 - 7.9e-07 28.7 3.6 1.4e-06 27.9 3.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 GAP89494.1 - 0.0013 18.0 4.6 0.0022 17.2 4.6 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 GAP89494.1 - 0.0035 17.4 0.1 0.0035 17.4 0.1 2.5 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term ATF7IP_BD PF16788.5 GAP89495.1 - 2.2 8.4 6.2 3.1 7.8 6.2 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain MFS_1 PF07690.16 GAP89496.1 - 3e-18 65.9 45.3 8.9e-18 64.3 44.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily SKG6 PF08693.10 GAP89497.1 - 1.7 8.1 4.6 3.5 7.1 4.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MRC1 PF09444.10 GAP89499.1 - 1.6e-43 148.7 18.1 1.6e-43 148.7 18.1 8.1 6 2 1 7 7 7 1 MRC1-like domain SAGA-Tad1 PF12767.7 GAP89500.1 - 2.2e-61 207.6 0.0 3e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit GCP_C_terminal PF04130.13 GAP89501.1 - 5.1e-99 331.6 0.5 5.1e-99 331.6 0.5 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 GAP89501.1 - 8.1e-83 278.5 0.0 2.5e-82 277.0 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal ApeA_NTD1 PF18862.1 GAP89501.1 - 0.1 12.2 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 ApeA N-terminal domain 1 Pkinase PF00069.25 GAP89502.1 - 1.3e-42 146.0 0.0 3.2e-40 138.1 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89502.1 - 3.8e-27 95.2 0.0 8.1e-27 94.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase 1-cysPrx_C PF10417.9 GAP89502.1 - 0.18 11.7 0.4 0.57 10.1 0.4 1.8 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin BTB PF00651.31 GAP89503.1 - 5.7e-13 49.1 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SDA1 PF05285.12 GAP89503.1 - 0.37 10.2 3.8 0.52 9.7 3.8 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GAP89503.1 - 1.6 6.8 6.8 2.1 6.4 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 GAP89503.1 - 1.7 9.0 7.1 4.5 7.7 7.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF347 PF03988.12 GAP89504.1 - 0.051 13.8 0.1 0.092 13.0 0.1 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Aminotran_4 PF01063.19 GAP89505.1 - 1.9e-27 96.6 0.0 2.4e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Peptidase_M75 PF09375.10 GAP89506.1 - 0.0049 16.4 2.8 0.025 14.1 0.3 2.2 2 0 0 2 2 2 1 Imelysin IgaA PF07095.11 GAP89506.1 - 0.0086 14.1 0.3 0.012 13.6 0.3 1.1 1 0 0 1 1 1 1 Intracellular growth attenuator protein IgaA CENP-U PF13097.6 GAP89506.1 - 0.023 14.7 1.8 0.053 13.5 1.8 1.6 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Ldh_1_C PF02866.18 GAP89506.1 - 0.05 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Pex19 PF04614.12 GAP89506.1 - 0.14 11.9 3.8 0.056 13.2 1.3 1.5 2 0 0 2 2 2 0 Pex19 protein family COG5 PF10392.9 GAP89506.1 - 0.14 12.3 7.1 0.52 10.5 0.2 3.1 1 1 2 3 3 3 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 GAP89506.1 - 0.18 11.1 5.7 0.34 10.2 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Kinesin_assoc PF16183.5 GAP89506.1 - 0.24 11.5 4.1 0.48 10.6 4.1 1.6 1 1 0 1 1 1 0 Kinesin-associated His_Phos_1 PF00300.22 GAP89507.1 - 6.5e-14 52.1 0.1 2.5e-13 50.2 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ERG4_ERG24 PF01222.17 GAP89508.1 - 2.2e-142 474.8 20.2 2.6e-142 474.6 20.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DNA_pol_E_B PF04042.16 GAP89509.1 - 1.1e-62 211.1 0.0 1.6e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.25 GAP89511.1 - 5.5e-76 255.4 0.0 7.6e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89511.1 - 5.7e-39 133.9 0.0 8.7e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 GAP89511.1 - 8.4e-22 77.8 2.4 1.2e-12 48.3 0.2 2.8 3 0 0 3 3 3 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 GAP89511.1 - 7.6e-16 58.0 0.5 2.4e-15 56.4 0.5 1.9 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 GAP89511.1 - 2.8e-07 30.2 0.0 5.7e-07 29.1 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 GAP89511.1 - 0.0062 15.5 0.1 0.013 14.5 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 GAP89511.1 - 0.014 14.2 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 GAP89511.1 - 0.11 12.4 0.4 0.51 10.2 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family NAD_binding_6 PF08030.12 GAP89512.1 - 1.9e-23 83.3 0.0 2.9e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 GAP89512.1 - 2.6e-15 56.7 14.1 2.6e-15 56.7 14.1 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAP89512.1 - 3.3e-12 46.4 0.0 1.2e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 GAP89512.1 - 0.003 18.2 0.0 0.56 10.9 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain MLD PF11647.8 GAP89513.1 - 0.074 13.3 0.3 0.62 10.4 0.1 2.6 1 1 1 2 2 2 0 Membrane Localization Domain KIP1 PF07765.12 GAP89513.1 - 0.11 12.6 0.2 0.11 12.6 0.2 2.6 3 0 0 3 3 3 0 KIP1-like protein DivIC PF04977.15 GAP89513.1 - 0.12 12.1 28.7 0.22 11.3 3.2 6.7 4 1 2 6 6 6 0 Septum formation initiator PHM7_cyt PF14703.6 GAP89513.1 - 0.57 10.4 8.1 0.62 10.3 5.9 2.3 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter TMPIT PF07851.13 GAP89513.1 - 2 7.5 9.1 0.68 9.1 2.1 2.5 1 1 1 3 3 3 0 TMPIT-like protein MCC-bdg_PDZ PF10506.9 GAP89513.1 - 2.6 8.1 7.4 1.2 9.2 0.9 3.7 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HALZ PF02183.18 GAP89513.1 - 4.1 7.7 7.3 3.7 7.9 0.3 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper Dioxygenase_C PF00775.21 GAP89514.1 - 7.2e-05 22.3 0.0 0.00029 20.3 0.0 1.8 2 0 0 2 2 2 1 Dioxygenase PGF-CTERM PF18204.1 GAP89514.1 - 1.3 9.1 5.3 2.6 8.2 5.3 1.5 1 0 0 1 1 1 0 PGF-CTERM motif Dioxygenase_C PF00775.21 GAP89515.1 - 2.1e-10 40.3 0.1 4.3e-10 39.3 0.1 1.5 1 1 0 1 1 1 1 Dioxygenase RTA1 PF04479.13 GAP89516.1 - 1.8e-43 148.6 11.4 2.5e-43 148.1 11.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF5453 PF17534.2 GAP89516.1 - 0.067 13.1 3.3 0.12 12.4 3.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5453) MFS_MOT1 PF16983.5 GAP89517.1 - 3.3e-60 201.3 37.1 1.7e-33 115.3 11.6 2.9 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily DUF2569 PF10754.9 GAP89517.1 - 0.12 12.8 9.3 0.1 13.1 6.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Forkhead PF00250.18 GAP89518.1 - 2.6e-15 56.4 0.0 5.3e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 GAP89518.1 - 0.00012 22.3 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Asp-B-Hydro_N PF05279.11 GAP89518.1 - 0.7 9.9 5.0 2.4 8.2 5.0 1.9 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region IFRD PF05004.13 GAP89520.1 - 2.8e-76 256.6 3.6 3.8e-76 256.1 3.6 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 GAP89520.1 - 0.004 16.3 0.1 0.0093 15.1 0.0 1.6 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal Arg_decarbox_C PF17944.1 GAP89520.1 - 0.012 16.2 0.1 0.041 14.4 0.1 2.0 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension HEAT_2 PF13646.6 GAP89520.1 - 0.069 13.5 0.1 1.6 9.2 0.0 2.3 1 1 0 2 2 2 0 HEAT repeats FHA PF00498.26 GAP89521.1 - 1.3e-09 38.3 0.0 3.7e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain Chitin_bind_4 PF00379.23 GAP89521.1 - 9.6 6.8 8.3 1.8 9.2 0.1 3.4 3 0 0 3 3 3 0 Insect cuticle protein WD40 PF00400.32 GAP89522.1 - 4.6e-37 125.4 18.6 3.1e-09 37.3 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP89522.1 - 2.1e-11 43.9 1.2 0.01 16.1 0.1 4.8 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP89522.1 - 2.5e-07 30.0 0.2 0.31 10.0 0.0 4.5 3 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 GAP89522.1 - 1.2e-05 24.4 2.4 5.1e-05 22.4 0.2 2.7 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 GAP89522.1 - 0.0002 20.2 4.9 0.9 8.1 0.1 4.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Frtz PF11768.8 GAP89522.1 - 0.0028 16.0 0.0 0.012 14.0 0.0 1.9 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 GAP89522.1 - 0.042 13.6 1.9 16 5.1 0.0 3.1 1 1 1 3 3 3 0 TUP1-like enhancer of split Nucleoporin_N PF08801.11 GAP89522.1 - 0.07 11.9 0.1 2.3 6.9 0.0 2.7 1 1 2 3 3 3 0 Nup133 N terminal like Pkinase PF00069.25 GAP89523.1 - 9.5e-09 35.0 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 GAP89523.1 - 1.3e-08 34.3 0.2 0.11 12.9 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat Pkinase_Tyr PF07714.17 GAP89523.1 - 3.2e-07 29.9 0.0 5.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 GAP89523.1 - 2e-06 28.1 0.4 0.0014 19.0 0.1 3.4 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 GAP89523.1 - 3.5e-06 27.1 0.0 1.1e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAP89523.1 - 9.7e-05 22.8 0.0 0.31 11.6 0.0 3.1 2 1 1 3 3 3 2 HEAT-like repeat Kinase-like PF14531.6 GAP89523.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Grg1 PF11034.8 GAP89523.1 - 0.78 10.0 2.8 0.46 10.7 0.3 1.9 2 0 0 2 2 2 0 Glucose-repressible protein Grg1 FAD_binding_4 PF01565.23 GAP89524.1 - 1.4e-23 83.2 0.2 2.3e-23 82.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GHMP_kinases_N PF00288.26 GAP89525.1 - 1.2e-09 38.3 0.1 2.6e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAP89525.1 - 6e-05 23.3 0.0 6e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal Hexapep PF00132.24 GAP89526.1 - 8.7e-14 50.6 15.5 6.6e-06 25.6 3.3 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAP89526.1 - 1.4e-12 47.1 17.9 8.1e-09 35.1 5.3 2.6 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 GAP89526.1 - 2e-10 40.8 0.0 2e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Maltose acetyltransferase Zn_clus PF00172.18 GAP89526.1 - 3.6e-09 36.6 8.8 7.5e-09 35.6 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3915 PF13054.6 GAP89526.1 - 0.097 12.7 11.9 0.33 10.9 11.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Cytomega_UL20A PF05984.12 GAP89526.1 - 0.24 11.7 2.3 0.57 10.5 0.1 2.6 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein ADH_zinc_N PF00107.26 GAP89528.1 - 9.8e-13 48.2 0.4 2.7e-12 46.8 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP89528.1 - 5.9e-05 22.9 0.0 0.00018 21.4 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 GAP89528.1 - 0.00086 18.8 0.6 0.0017 17.9 0.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 GAP89528.1 - 0.00092 18.6 1.1 0.0015 17.9 1.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 GAP89528.1 - 0.0012 18.5 0.3 0.0019 17.8 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family Fungal_trans PF04082.18 GAP89529.1 - 2.9e-16 59.3 1.3 5.2e-16 58.5 1.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP89529.1 - 3.5e-08 33.4 9.3 3.5e-08 33.4 9.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 GAP89530.1 - 4.9e-29 101.5 0.0 7.8e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP89530.1 - 9.3e-16 58.2 0.0 3.1e-15 56.5 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AIM24 PF01987.17 GAP89531.1 - 1.2e-48 165.6 0.2 1.5e-48 165.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ndc1_Nup PF09531.10 GAP89531.1 - 0.056 12.1 2.9 0.062 12.0 2.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fungal_trans_2 PF11951.8 GAP89532.1 - 4e-06 25.9 0.5 4e-06 25.9 0.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP89532.1 - 3.5e-05 23.8 2.2 3.5e-05 23.8 2.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TraS PF10624.9 GAP89532.1 - 0.11 12.5 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS WAK_assoc PF14380.6 GAP89532.1 - 0.8 10.5 5.6 2 9.2 4.5 2.2 2 0 0 2 2 2 0 Wall-associated receptor kinase C-terminal PAM2 PF07145.15 GAP89533.1 - 0.029 14.0 0.1 0.07 12.8 0.1 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Med1 PF10744.9 GAP89534.1 - 8.1e-96 321.6 0.0 1.1e-95 321.2 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Med13_C PF06333.12 GAP89536.1 - 0.019 14.3 3.4 0.026 13.8 3.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Dicty_REP PF05086.12 GAP89536.1 - 0.53 8.2 12.6 0.69 7.8 12.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mitofilin PF09731.9 GAP89536.1 - 6.1 5.6 16.6 8 5.2 16.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NAD_binding_10 PF13460.6 GAP89537.1 - 7e-16 58.7 2.2 1.8e-14 54.0 0.1 2.6 2 1 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 GAP89537.1 - 1.2e-14 54.5 0.8 5.8e-13 48.9 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family Serglycin PF04360.12 GAP89537.1 - 0.001 19.0 0.2 0.0018 18.3 0.2 1.3 1 0 0 1 1 1 1 Serglycin Patatin PF01734.22 GAP89538.1 - 8.5e-09 35.9 0.1 2.6e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase Gln-synt_C PF00120.24 GAP89542.1 - 6.1e-17 61.6 0.0 3.3e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 GAP89542.1 - 4.4e-13 48.8 0.0 9.2e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MOSC PF03473.17 GAP89544.1 - 2e-25 89.3 0.0 4.5e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 GAP89544.1 - 1.1e-11 44.5 0.7 2.5e-11 43.4 0.7 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 GAP89544.1 - 1e-06 29.3 0.0 1.5e-05 25.6 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain 3-alpha PF03475.14 GAP89544.1 - 2.9e-05 23.8 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 3-alpha domain NAD_binding_6 PF08030.12 GAP89544.1 - 0.18 11.9 0.6 6.1 6.9 0.2 2.5 1 1 0 2 2 2 0 Ferric reductase NAD binding domain adh_short PF00106.25 GAP89545.1 - 3.7e-36 124.4 0.0 6.6e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP89545.1 - 1.1e-26 93.9 0.0 1.5e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 GAP89545.1 - 4e-06 26.9 0.1 1.2e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAP89545.1 - 1e-05 25.1 0.0 2.3e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAP89545.1 - 0.0018 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 GAP89545.1 - 0.048 13.6 0.1 0.24 11.3 0.1 2.0 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 GAP89545.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 GAP89545.1 - 0.13 11.8 0.0 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Eno-Rase_NADH_b PF12242.8 GAP89545.1 - 0.14 12.0 0.4 0.35 10.6 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HMGL-like PF00682.19 GAP89546.1 - 6e-73 245.7 0.0 1.1e-72 244.8 0.0 1.4 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 GAP89546.1 - 3.2e-22 78.8 0.0 6.9e-22 77.8 0.0 1.6 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Epimerase PF01370.21 GAP89547.1 - 3.7e-08 33.1 0.0 3.6e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP89547.1 - 1.3e-05 25.2 0.1 3e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAP89547.1 - 0.006 16.2 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 GAP89547.1 - 0.0098 14.9 0.0 0.033 13.2 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 GAP89547.1 - 0.022 14.2 0.1 0.04 13.4 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 GAP89547.1 - 0.078 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ank_2 PF12796.7 GAP89549.1 - 1.4e-24 86.5 0.0 5.8e-07 30.0 0.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP89549.1 - 1.7e-19 69.9 2.1 0.01 16.4 0.0 6.9 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 GAP89549.1 - 1.3e-17 63.4 2.2 0.00084 19.7 0.0 7.2 5 2 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 GAP89549.1 - 1.1e-14 54.3 2.7 5.7e-05 23.3 0.0 6.5 4 3 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP89549.1 - 2.6e-13 48.8 0.6 0.18 12.4 0.0 7.7 6 2 1 7 7 7 3 Ankyrin repeat Glt_symporter PF03616.14 GAP89549.1 - 0.027 13.1 0.0 0.04 12.6 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Neisseria_PilC PF05567.11 GAP89549.1 - 0.028 13.4 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain DUF1843 PF08898.10 GAP89549.1 - 0.12 12.9 0.5 6.8 7.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Ank_2 PF12796.7 GAP89550.1 - 1.2e-29 102.6 0.9 2.9e-08 34.2 0.0 7.7 4 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP89550.1 - 3.9e-22 78.3 6.2 1.8e-07 31.5 0.0 9.6 8 2 2 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP89550.1 - 3.5e-20 69.9 14.2 0.0079 16.6 0.1 12.0 13 0 0 13 13 13 4 Ankyrin repeat Ank_5 PF13857.6 GAP89550.1 - 8.5e-12 45.1 4.5 0.14 12.5 0.0 6.3 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 GAP89550.1 - 1.7e-08 34.5 11.4 0.22 12.0 0.1 8.1 10 0 0 10 10 10 3 Ankyrin repeat Clr5 PF14420.6 GAP89550.1 - 0.00022 21.4 1.9 0.0005 20.2 1.9 1.6 1 0 0 1 1 1 1 Clr5 domain zf-C2H2 PF00096.26 GAP89551.1 - 0.031 14.7 2.0 0.031 14.7 2.0 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP89551.1 - 0.36 11.8 5.9 0.39 11.7 1.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 GAP89551.1 - 2.7 8.3 8.5 9.2 6.7 3.1 3.7 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding ADH_zinc_N_2 PF13602.6 GAP89552.1 - 1.3e-21 78.1 0.1 1.9e-21 77.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAP89552.1 - 4.7e-21 75.1 0.4 6.6e-21 74.6 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DLH PF01738.18 GAP89553.1 - 4.9e-24 85.1 0.0 1.1e-21 77.4 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 GAP89553.1 - 0.0077 15.9 0.0 0.58 9.7 0.0 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAP89553.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Rep_fac-A_C PF08646.10 GAP89554.1 - 1.6e-58 196.6 3.3 5.1e-57 191.7 0.6 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 GAP89554.1 - 3.4e-38 129.5 0.7 5.7e-37 125.6 0.1 2.4 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 GAP89554.1 - 9.2e-22 77.0 0.0 1.9e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 GAP89554.1 - 1.7e-16 60.0 0.9 1.4e-11 44.2 0.0 4.2 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 GAP89554.1 - 2.2e-06 27.6 0.7 0.0089 15.8 0.1 3.0 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 GAP89554.1 - 0.00048 20.4 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF223 DUF5521 PF17659.1 GAP89554.1 - 0.0094 13.9 0.1 0.047 11.6 0.0 2.1 2 1 0 2 2 2 1 Family of unknown function (DUF5521) zf-like PF04071.12 GAP89554.1 - 0.014 15.3 0.7 0.082 12.8 0.3 2.2 2 0 0 2 2 2 0 Cysteine-rich small domain DUF4503 PF14951.6 GAP89554.1 - 0.12 10.9 0.2 0.19 10.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) PCI PF01399.27 GAP89555.1 - 0.00036 21.0 0.0 0.0007 20.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain YfiO PF13525.6 GAP89555.1 - 0.034 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein TPR_2 PF07719.17 GAP89555.1 - 0.058 13.5 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Bac_rhodopsin PF01036.18 GAP89556.1 - 7.3e-47 159.8 19.2 9.4e-47 159.4 19.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Heliorhodopsin PF18761.1 GAP89556.1 - 0.015 14.6 8.7 0.029 13.7 8.1 1.7 1 1 1 2 2 2 0 Heliorhodopsin NACHT PF05729.12 GAP89557.1 - 7.3e-08 32.5 0.0 1.7e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP89557.1 - 2.7e-05 24.6 0.1 0.00021 21.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP89557.1 - 0.00018 21.8 0.0 0.0018 18.6 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 GAP89557.1 - 0.0042 17.6 0.0 0.028 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 GAP89557.1 - 0.0046 16.9 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 GAP89557.1 - 0.013 15.4 0.4 0.044 13.7 0.0 2.0 3 0 0 3 3 2 0 RsgA GTPase RNA_helicase PF00910.22 GAP89557.1 - 0.014 15.8 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 GAP89557.1 - 0.015 15.5 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 GAP89557.1 - 0.021 14.1 0.8 0.14 11.4 0.0 2.4 3 0 0 3 3 3 0 KAP family P-loop domain AAA_29 PF13555.6 GAP89557.1 - 0.03 14.1 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 GAP89557.1 - 0.047 13.4 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAP89557.1 - 0.062 13.8 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 GAP89557.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 GAP89557.1 - 0.11 12.2 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4116 PF13475.6 GAP89557.1 - 0.12 12.2 0.1 15 5.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) cobW PF02492.19 GAP89557.1 - 0.15 11.6 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain L27 PF02828.16 GAP89557.1 - 1.3 8.8 3.3 3.1 7.6 0.4 3.1 4 0 0 4 4 3 0 L27 domain 2Fe-2S_thioredx PF01257.19 GAP89558.1 - 1.2e-58 197.0 0.0 1.5e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Kelch_5 PF13854.6 GAP89559.1 - 2.9e-13 49.4 0.1 0.00072 19.5 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 GAP89559.1 - 4.8e-11 42.5 11.2 1.5e-05 24.9 0.1 6.1 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAP89559.1 - 2.3e-09 37.3 20.3 6.5e-06 26.3 0.1 7.7 8 1 0 8 8 8 2 Galactose oxidase, central domain Kelch_6 PF13964.6 GAP89559.1 - 2.5e-09 37.1 4.9 0.017 15.4 0.0 5.5 6 1 1 7 7 6 3 Kelch motif Kelch_1 PF01344.25 GAP89559.1 - 3.5e-09 36.1 0.5 0.13 11.8 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 GAP89559.1 - 2.3e-05 24.1 1.0 0.07 13.1 0.0 4.9 6 0 0 6 6 5 1 Kelch motif Presenilin PF01080.17 GAP89559.1 - 0.0018 17.1 8.0 0.0024 16.7 8.0 1.1 1 0 0 1 1 1 1 Presenilin CCDC106 PF15794.5 GAP89559.1 - 0.027 14.2 13.2 0.042 13.6 13.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Nop14 PF04147.12 GAP89559.1 - 0.04 12.1 40.4 0.061 11.5 40.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAP89559.1 - 0.098 10.9 32.6 0.14 10.4 32.6 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 GAP89559.1 - 0.11 12.6 39.0 0.26 11.4 39.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Nop53 PF07767.11 GAP89559.1 - 0.73 9.2 38.6 1.2 8.4 38.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DNA_pol_phi PF04931.13 GAP89559.1 - 1.1 7.3 47.6 1.9 6.5 47.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 GAP89559.1 - 1.1 8.6 43.6 1.9 7.8 43.6 1.2 1 0 0 1 1 1 0 SDA1 DUF4614 PF15391.6 GAP89559.1 - 2.7 8.0 13.1 5.6 6.9 13.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Hid1 PF12722.7 GAP89559.1 - 3.3 5.7 18.0 4.5 5.3 18.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-T_N PF16171.5 GAP89559.1 - 3.7 6.3 10.9 6.7 5.5 10.9 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus Neur_chan_memb PF02932.16 GAP89559.1 - 4.1 7.4 8.0 7.8 6.5 8.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region VIR_N PF15912.5 GAP89559.1 - 4.1 6.9 15.5 10 5.6 15.5 1.7 1 0 0 1 1 1 0 Virilizer, N-terminal zf-C2H2 PF00096.26 GAP89560.1 - 2.4e-08 34.0 48.9 0.0011 19.4 6.6 7.6 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP89560.1 - 0.00055 20.6 61.5 0.0097 16.7 5.4 8.3 9 0 0 9 9 9 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP89560.1 - 0.047 14.0 0.3 0.047 14.0 0.3 5.8 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 GAP89560.1 - 0.68 10.0 6.8 7.6 6.6 0.7 2.6 2 0 0 2 2 2 0 CpXC protein zf-C2H2_6 PF13912.6 GAP89560.1 - 0.91 9.6 16.2 0.86 9.7 5.7 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 GAP89560.1 - 2.5 8.6 0.0 2.5 8.6 0.0 6.3 7 0 0 7 7 7 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 GAP89560.1 - 4.9 7.9 20.0 2.2 9.0 1.0 5.0 2 2 3 5 5 5 0 FOXP coiled-coil domain Cyt-b5 PF00173.28 GAP89561.1 - 2e-10 40.7 0.1 2.2e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Myco_19_kDa PF05481.12 GAP89561.1 - 0.23 11.7 1.3 0.5 10.6 0.5 1.9 1 1 1 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen TPR_12 PF13424.6 GAP89562.1 - 1.2e-07 31.9 8.3 0.021 15.1 0.1 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAP89562.1 - 0.00089 19.2 4.0 0.36 11.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAP89562.1 - 0.0026 17.7 0.8 19 5.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 GAP89562.1 - 0.0097 15.6 0.5 8.1 6.1 0.1 3.6 4 0 0 4 4 4 1 26S proteasome subunit RPN7 TPR_1 PF00515.28 GAP89562.1 - 0.017 14.9 2.0 8 6.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAP89562.1 - 0.12 12.6 1.1 19 5.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 GAP89563.1 - 0.00031 21.3 13.0 0.13 13.2 0.3 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 GAP89563.1 - 0.0068 16.8 15.8 0.024 15.1 0.3 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type SpoIIE PF07228.12 GAP89563.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) zf-met PF12874.7 GAP89563.1 - 1 9.8 3.3 47 4.6 1.1 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type p450 PF00067.22 GAP89566.1 - 8.1e-55 186.4 0.0 8.8e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_26 PF02156.15 GAP89566.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 Amnionless PF14828.6 GAP89567.1 - 0.08 11.8 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless Pam17 PF08566.10 GAP89567.1 - 0.18 11.7 2.0 0.2 11.5 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 TP2 PF01254.18 GAP89567.1 - 2.5 8.7 10.2 2.5 8.7 7.4 1.9 2 0 0 2 2 2 0 Nuclear transition protein 2 ODC_AZ PF02100.17 GAP89568.1 - 1.9e-44 150.3 0.1 2.6e-44 149.8 0.1 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme His_biosynth PF00977.21 GAP89569.1 - 7.2e-50 169.6 0.1 2.6e-49 167.8 0.1 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 GAP89569.1 - 1.1e-20 74.2 0.0 1.8e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 GAP89569.1 - 3.5e-10 40.0 0.0 1.4e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 GAP89569.1 - 5.4e-08 32.7 0.0 1.6e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.17 GAP89569.1 - 0.0031 16.7 0.1 0.0071 15.5 0.1 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.13 GAP89569.1 - 0.015 15.1 0.0 0.47 10.2 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 Pantoate_transf PF02548.15 GAP89569.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase NMO PF03060.15 GAP89569.1 - 0.19 11.0 1.8 0.22 10.8 0.4 1.7 2 0 0 2 2 2 0 Nitronate monooxygenase TFIIIC_sub6 PF10419.9 GAP89570.1 - 8e-22 76.9 0.0 1.5e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain RNA_Me_trans PF04252.13 GAP89571.1 - 8.8e-46 156.0 0.1 1e-45 155.8 0.1 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase RNA_Me_trans PF04252.13 GAP89572.1 - 2.1e-12 47.0 0.0 2.5e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Ino80_Iec3 PF14612.6 GAP89573.1 - 5.4e-56 190.9 6.5 1.2e-29 104.7 5.0 2.4 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling YabA PF06156.13 GAP89573.1 - 1.8 9.3 4.3 0.36 11.5 0.3 1.9 2 0 0 2 2 2 0 Initiation control protein YabA UPF0160 PF03690.13 GAP89574.1 - 3.9e-126 421.0 0.0 4.5e-126 420.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Mito_fiss_Elm1 PF06258.11 GAP89574.1 - 0.029 13.5 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Endosulfine PF04667.17 GAP89575.1 - 3.3e-28 97.6 0.2 5.5e-28 96.9 0.2 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Sugar_tr PF00083.24 GAP89577.1 - 1.3e-90 304.4 18.7 1.7e-90 304.0 18.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP89577.1 - 2.3e-22 79.4 37.6 8.1e-16 57.9 12.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Vps62 PF06101.11 GAP89577.1 - 5.4e-10 38.2 1.9 5.7e-10 38.1 0.3 1.7 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 Acetyltransf_7 PF13508.7 GAP89578.1 - 5.3e-08 33.2 0.0 7.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAP89578.1 - 4.9e-07 29.7 0.0 5.9e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP89578.1 - 8.5e-07 28.9 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 GAP89578.1 - 4.1e-05 23.8 0.0 5.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Esterase_phd PF10503.9 GAP89579.1 - 3.7e-21 75.6 0.2 5.1e-21 75.2 0.2 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 GAP89579.1 - 1.6e-10 40.8 0.4 2.4e-10 40.2 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 GAP89579.1 - 0.0092 14.9 0.1 0.015 14.2 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP89579.1 - 0.0092 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP89579.1 - 0.013 14.8 0.2 0.046 13.0 0.2 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Phage_holin_2_3 PF16080.5 GAP89579.1 - 0.41 10.4 1.9 19 5.1 0.2 3.1 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Ank_2 PF12796.7 GAP89581.1 - 4.3e-05 24.0 0.0 0.026 15.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP89581.1 - 0.0024 18.1 0.1 4.8 7.6 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP89581.1 - 0.0031 17.9 0.0 0.042 14.4 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 GAP89581.1 - 0.1 13.2 0.0 2 9.1 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeats (many copies) FCH PF00611.23 GAP89582.1 - 4.7e-23 81.3 0.1 4.7e-23 81.3 0.1 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 GAP89582.1 - 1.5e-18 66.4 0.5 2.8e-13 49.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 GAP89582.1 - 2.7e-15 56.0 5.6 4.2e-15 55.4 5.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 GAP89582.1 - 1.9e-14 53.0 0.1 4.9e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 GAP89582.1 - 0.001 18.7 0.1 0.49 10.1 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 GAP89582.1 - 0.0046 17.0 0.4 0.93 9.6 0.0 3.8 4 0 0 4 4 4 1 SH3 domain C1_2 PF03107.16 GAP89582.1 - 0.009 16.3 4.8 0.016 15.5 4.8 1.4 1 0 0 1 1 1 1 C1 domain SH3_3 PF08239.11 GAP89582.1 - 0.018 15.3 0.7 1.8 8.9 0.3 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain 7TM_GPCR_Sri PF10327.9 GAP89582.1 - 0.095 11.9 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri LETM1 PF07766.13 GAP89582.1 - 0.24 10.7 7.4 0.66 9.3 0.2 2.4 2 0 0 2 2 2 0 LETM1-like protein Allexi_40kDa PF05549.11 GAP89582.1 - 2.4 7.6 9.0 0.38 10.2 0.5 2.5 2 1 0 2 2 2 0 Allexivirus 40kDa protein Spc7 PF08317.11 GAP89582.1 - 2.5 6.9 21.3 0.36 9.7 8.2 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein COG2 PF06148.11 GAP89582.1 - 5.3 7.1 15.0 4.8 7.3 3.7 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-RING_9 PF13901.6 GAP89582.1 - 6.2 6.7 12.2 0.34 10.9 3.6 2.6 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon SET PF00856.28 GAP89583.1 - 3.3e-11 43.9 1.9 2.1e-10 41.2 0.1 2.8 3 1 0 3 3 3 1 SET domain CBM_1 PF00734.18 GAP89583.1 - 0.016 15.2 0.9 0.031 14.2 0.9 1.5 1 0 0 1 1 1 0 Fungal cellulose binding domain CTU2 PF10288.9 GAP89583.1 - 0.11 12.8 0.1 1 9.6 0.0 2.1 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Glyco_hydro_72 PF03198.14 GAP89584.1 - 1.7e-126 421.8 2.0 2e-126 421.5 2.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 GAP89584.1 - 2.4e-05 23.9 0.5 0.00025 20.6 0.5 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TauD PF02668.16 GAP89585.1 - 2.5e-44 152.1 0.5 3.6e-44 151.6 0.5 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family But2 PF09792.9 GAP89586.1 - 2.4e-05 24.8 0.0 0.00016 22.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain XRCC4 PF06632.12 GAP89586.1 - 0.064 12.1 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SNF2_N PF00176.23 GAP89587.1 - 1.4e-47 162.1 0.0 2e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 GAP89587.1 - 4.7e-22 77.9 0.1 1.2e-21 76.5 0.1 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 GAP89587.1 - 5.4e-20 71.8 0.0 8.2e-19 68.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 GAP89587.1 - 7.3e-07 28.7 0.0 1.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAP89587.1 - 0.0004 20.4 0.0 0.0062 16.5 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit GTP_EFTU PF00009.27 GAP89588.1 - 2.7e-51 173.9 0.0 5e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 GAP89588.1 - 1.4e-43 147.4 5.8 2.3e-43 146.7 5.8 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 GAP89588.1 - 6.3e-20 71.0 0.0 1.5e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAP89588.1 - 1.9e-06 28.2 0.1 5.3e-06 26.7 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAP89588.1 - 1.8e-05 24.8 0.0 4.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 GAP89588.1 - 2.8e-05 23.8 0.0 0.0001 22.0 0.0 1.9 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 GAP89588.1 - 3.2e-05 23.9 0.0 9.1e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 GAP89588.1 - 5.4e-05 23.0 0.0 0.00016 21.5 0.0 1.8 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain Roc PF08477.13 GAP89588.1 - 0.0093 16.2 0.0 0.17 12.1 0.0 2.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAP89588.1 - 0.011 15.2 0.0 0.032 13.7 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF5070 PF16802.5 GAP89588.1 - 0.055 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5070) MMR_HSR1_Xtn PF16897.5 GAP89588.1 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Snurportin1 PF11538.8 GAP89588.1 - 0.24 11.6 1.3 0.57 10.4 1.3 1.6 1 0 0 1 1 1 0 Snurportin1 MR_MLE_C PF13378.6 GAP89589.1 - 6.8e-52 176.2 0.0 9e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 GAP89589.1 - 4.1e-20 72.1 0.0 8.3e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.6 GAP89590.1 - 1.1e-49 169.2 2.4 1.4e-49 168.8 2.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP89590.1 - 1.6e-48 164.8 0.5 1.9e-48 164.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP89590.1 - 1.2e-11 44.8 2.9 2.5e-11 43.8 2.9 1.5 1 1 0 1 1 1 1 KR domain PALP PF00291.25 GAP89590.1 - 0.0011 18.4 1.0 0.0014 18.1 0.3 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 GAP89590.1 - 0.0019 17.7 0.2 0.0032 17.0 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_4 PF13439.6 GAP89590.1 - 0.0085 16.1 0.3 2.8 7.9 0.0 2.6 3 0 0 3 3 3 2 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 GAP89590.1 - 0.033 13.9 0.2 0.19 11.4 0.0 2.0 2 1 0 2 2 2 0 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 GAP89590.1 - 0.069 13.6 6.0 2.9 8.3 0.3 3.1 3 0 0 3 3 3 0 Glycosyl transferase 4-like domain DHDPS PF00701.22 GAP89591.1 - 6.1e-41 140.0 0.0 7.5e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FMN_dh PF01070.18 GAP89592.1 - 5.1e-108 361.2 0.0 6.5e-108 360.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 GAP89592.1 - 3.4e-19 68.7 0.0 8.4e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 GAP89592.1 - 4.4e-08 32.7 0.0 9.1e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAP89592.1 - 0.00017 20.7 0.2 0.0013 17.8 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_syn_central PF04898.14 GAP89592.1 - 0.00071 19.1 0.0 0.0014 18.2 0.0 1.4 2 0 0 2 2 2 1 Glutamate synthase central domain NMO PF03060.15 GAP89592.1 - 0.0049 16.3 0.1 0.0077 15.7 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 GAP89592.1 - 0.069 12.5 1.3 1.6 8.0 0.1 2.5 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG ApbA_C PF08546.11 GAP89593.1 - 4e-30 104.6 0.0 5.7e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 GAP89593.1 - 1.1e-25 90.0 0.0 6.9e-23 81.0 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.21 GAP89594.1 - 1.8e-51 175.1 0.0 2.6e-50 171.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_90 PF05686.12 GAP89595.1 - 5.1e-15 55.3 9.0 8.8e-13 47.9 8.0 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_L7Ae PF01248.26 GAP89596.1 - 5.2e-28 96.6 0.9 6.8e-28 96.2 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 GAP89596.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain TauD PF02668.16 GAP89597.1 - 6.3e-29 101.6 0.0 1.1e-28 100.8 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sirohm_synth_C PF14823.6 GAP89597.1 - 0.14 11.8 0.3 0.27 10.9 0.3 1.3 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Sugar_tr PF00083.24 GAP89598.1 - 3.5e-78 263.5 18.5 4e-78 263.3 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP89598.1 - 2.6e-24 85.8 26.1 2.6e-24 85.8 26.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3712 PF12505.8 GAP89599.1 - 1.6e-28 99.5 0.8 3e-28 98.6 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) QCR10 PF09796.9 GAP89599.1 - 0.18 11.9 0.3 0.4 10.8 0.3 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) LIN52 PF10044.9 GAP89600.1 - 1.7e-05 25.4 0.2 1.2e+02 3.4 0.0 7.5 6 2 1 8 8 8 0 Retinal tissue protein MauJ PF17419.2 GAP89600.1 - 0.00013 21.5 0.3 3.9 6.9 0.0 4.0 2 1 1 4 4 4 3 Methylamine utilization protein MauJ PreAtp-grasp PF18604.1 GAP89600.1 - 0.041 13.5 0.0 18 5.0 0.0 4.0 3 0 0 3 3 3 0 Pre ATP-grasp domain Adaptin_N PF01602.20 GAP89600.1 - 0.062 11.9 0.4 2.2 6.8 0.0 3.1 3 1 0 3 3 3 0 Adaptin N terminal region MIF4G PF02854.19 GAP89600.1 - 0.28 10.8 6.4 8.3 6.0 0.1 4.6 4 1 1 5 5 5 0 MIF4G domain RPW8 PF05659.11 GAP89600.1 - 0.5 10.0 9.1 8.4 6.1 0.1 5.6 5 2 1 6 6 6 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SAD_SRA PF02182.17 GAP89601.1 - 4.1e-08 33.1 0.0 6.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain TruD PF01142.18 GAP89602.1 - 1.5e-61 208.5 0.5 3.3e-56 190.9 0.1 3.7 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) ERCC3_RAD25_C PF16203.5 GAP89603.1 - 1.5e-118 394.5 1.3 2.5e-118 393.7 1.3 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 GAP89603.1 - 3.3e-35 121.0 0.0 1.1e-34 119.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP89603.1 - 4.3e-14 52.9 0.0 9.7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAP89603.1 - 2.4e-09 37.5 0.1 5.6e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 GAP89603.1 - 3.2e-07 29.4 0.0 4.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DHOase PF12890.7 GAP89603.1 - 0.016 15.1 0.1 0.05 13.5 0.0 1.8 2 0 0 2 2 2 0 Dihydro-orotase-like TrkH PF02386.16 GAP89604.1 - 6.1e-141 470.3 4.4 6.1e-141 470.3 4.4 1.9 2 0 0 2 2 2 1 Cation transport protein DUF1143 PF06608.11 GAP89604.1 - 0.014 15.4 0.3 0.029 14.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) Ribosomal_L19 PF01245.20 GAP89605.1 - 1.3e-13 50.9 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 Aminotran_5 PF00266.19 GAP89606.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V PALP PF00291.25 GAP89607.1 - 6.7e-67 226.0 0.8 8.1e-67 225.7 0.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SH3_1 PF00018.28 GAP89608.1 - 9.1e-06 25.2 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAP89608.1 - 3e-05 23.8 0.0 6.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain ZZ PF00569.17 GAP89608.1 - 0.052 13.4 13.9 0.54 10.1 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, ZZ type Amino_oxidase PF01593.24 GAP89612.1 - 4.5e-41 141.6 0.0 1.1e-40 140.4 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAP89612.1 - 1.2e-15 57.5 0.1 2.4e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP89612.1 - 4.8e-06 26.0 0.0 1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAP89612.1 - 1.9e-05 24.1 0.4 2.9e-05 23.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 GAP89612.1 - 3.6e-05 24.3 0.0 6.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP89612.1 - 0.00034 19.8 0.7 0.00055 19.1 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP89612.1 - 0.0012 18.6 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAP89612.1 - 0.0019 17.0 0.1 0.0031 16.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.18 GAP89612.1 - 0.0033 17.3 0.2 0.0061 16.5 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 GAP89612.1 - 0.0051 16.1 0.1 0.0097 15.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 GAP89612.1 - 0.01 15.0 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAP89612.1 - 0.016 14.5 0.3 0.024 13.9 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 GAP89612.1 - 0.018 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 GAP89612.1 - 0.074 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAP89612.1 - 0.15 11.0 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ECH_1 PF00378.20 GAP89613.1 - 2e-74 250.1 0.1 2.3e-74 249.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAP89613.1 - 1.1e-34 120.5 0.1 5.1e-32 111.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 GAP89614.1 - 4.7e-79 264.1 6.3 5.4e-79 263.9 6.3 1.0 1 0 0 1 1 1 1 Rer1 family Paf1 PF03985.13 GAP89615.1 - 5.5e-83 279.3 1.3 6.2e-83 279.1 1.3 1.0 1 0 0 1 1 1 1 Paf1 Catalase PF00199.19 GAP89616.1 - 4.6e-154 513.2 0.9 5.9e-97 325.2 0.0 2.1 2 0 0 2 2 2 2 Catalase Catalase_C PF18011.1 GAP89616.1 - 2.9e-36 124.4 0.4 5e-36 123.6 0.4 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 GAP89616.1 - 3.1e-12 46.5 0.1 7e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Haspin_kinase PF12330.8 GAP89617.1 - 5.4e-37 127.6 0.0 7.2e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAP89617.1 - 0.012 15.6 1.2 0.036 14.0 1.2 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Myc_N PF01056.18 GAP89617.1 - 0.31 10.9 1.7 0.46 10.3 1.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF1682 PF07946.14 GAP89618.1 - 1.2e-113 379.6 0.2 1.4e-113 379.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Thiamine_BP PF01910.17 GAP89619.1 - 9.3e-33 112.0 0.8 1.1e-32 111.8 0.8 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Polysacc_deac_1 PF01522.21 GAP89619.1 - 0.0017 18.2 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF5349 PF17298.2 GAP89620.1 - 4.4 7.0 13.3 0.26 11.0 0.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5349) CDC37_N PF03234.14 GAP89621.1 - 7.3e-48 162.7 0.1 7.3e-48 162.7 0.1 2.6 4 0 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 GAP89621.1 - 2.7e-38 130.5 3.4 5.6e-38 129.5 1.2 2.3 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 GAP89621.1 - 3.9e-30 103.9 0.3 3.9e-30 103.9 0.3 2.0 2 1 0 2 2 2 1 Cdc37 C terminal domain Phage_GP20 PF06810.11 GAP89621.1 - 0.074 12.9 5.7 0.13 12.1 0.7 2.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF5340 PF17275.2 GAP89621.1 - 0.61 10.3 3.0 0.52 10.5 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5340) CENP-Q PF13094.6 GAP89621.1 - 1.8 8.7 9.0 0.43 10.8 5.0 2.0 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit GGACT PF06094.12 GAP89622.1 - 1.5e-08 35.3 0.0 2.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like SMC_N PF02463.19 GAP89623.1 - 1e-61 208.2 15.4 2.4e-61 207.0 15.4 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAP89623.1 - 4.9e-29 101.0 0.0 1.9e-28 99.1 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 GAP89623.1 - 7.1e-20 72.0 29.5 2.2e-15 57.3 4.4 4.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAP89623.1 - 1.2e-16 61.4 0.4 1.1e-07 31.9 0.0 3.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAP89623.1 - 2.8e-06 28.0 45.4 2.8e-06 28.0 45.4 7.4 2 2 1 3 3 3 1 AAA domain SbcCD_C PF13558.6 GAP89623.1 - 0.00025 21.2 0.0 0.0019 18.4 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 GAP89623.1 - 0.0036 17.0 0.0 0.0086 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynein_heavy PF03028.15 GAP89623.1 - 0.046 13.8 0.8 20 5.3 0.3 3.1 2 0 0 2 2 2 0 Dynein heavy chain region D6 P-loop domain PCI PF01399.27 GAP89623.1 - 0.96 10.0 4.7 0.62 10.6 1.3 2.6 2 0 0 2 2 2 0 PCI domain DUF3535 PF12054.8 GAP89624.1 - 2.3e-113 379.7 0.1 2.2e-109 366.6 0.0 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 GAP89624.1 - 1.7e-64 217.8 0.0 4.5e-64 216.4 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.22 GAP89624.1 - 2.5e-20 70.8 0.7 0.0049 17.0 0.0 8.3 7 0 0 7 7 7 6 HEAT repeat Helicase_C PF00271.31 GAP89624.1 - 3.5e-19 69.2 0.0 2e-18 66.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT_2 PF13646.6 GAP89624.1 - 1.1e-10 41.7 0.3 4.9e-05 23.6 0.0 5.6 5 0 0 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 GAP89624.1 - 2.7e-05 24.7 0.3 1.3 9.7 0.0 4.3 2 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region DEAD PF00270.29 GAP89624.1 - 0.00021 21.1 0.1 0.0083 15.9 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase HEAT_EZ PF13513.6 GAP89624.1 - 0.00031 21.2 7.4 5.2 7.7 0.0 7.2 8 0 0 8 8 8 2 HEAT-like repeat CLASP_N PF12348.8 GAP89624.1 - 0.004 16.8 0.1 0.33 10.5 0.0 3.2 3 0 0 3 3 3 1 CLASP N terminal ERCC3_RAD25_C PF16203.5 GAP89624.1 - 0.044 13.0 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase TFIIA PF03153.13 GAP89625.1 - 0.00084 19.5 31.5 0.0014 18.8 31.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 GAP89625.1 - 2.3 7.0 12.7 1.4 7.7 9.6 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain SR-25 PF10500.9 GAP89625.1 - 9.6 5.7 24.5 0.45 10.1 14.8 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S8 PF00082.22 GAP89626.1 - 1.4e-30 106.6 13.4 3.5e-30 105.3 13.4 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAP89626.1 - 2.5e-11 44.1 2.1 6.5e-11 42.8 2.1 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 HRI1 PF16815.5 GAP89627.1 - 1.6e-68 230.8 0.9 1.8e-68 230.7 0.9 1.0 1 0 0 1 1 1 1 Protein HRI1 FAD_binding_3 PF01494.19 GAP89628.1 - 4.9e-11 42.5 0.2 0.0001 21.7 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 GAP89628.1 - 3.6e-08 33.4 5.4 0.00036 20.2 2.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP89628.1 - 8e-08 32.4 0.5 2.1e-07 31.0 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP89628.1 - 2.4e-06 27.0 0.3 1.4e-05 24.5 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAP89628.1 - 0.0003 20.2 1.9 0.027 13.8 0.3 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 GAP89628.1 - 0.00049 19.3 2.6 0.001 18.2 2.6 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 GAP89628.1 - 0.0018 17.4 1.0 0.0077 15.4 1.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAP89628.1 - 0.0074 15.2 1.9 0.057 12.3 0.4 2.2 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 GAP89628.1 - 0.0086 14.8 1.8 0.044 12.5 1.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAP89628.1 - 0.0092 15.3 0.7 0.042 13.1 1.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP89628.1 - 0.014 16.0 0.9 0.039 14.5 0.9 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAP89628.1 - 0.022 14.2 1.3 0.034 13.5 1.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAP89628.1 - 0.048 12.9 0.8 0.08 12.2 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GAP89628.1 - 0.058 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 GAP89628.1 - 0.1 12.6 1.2 0.79 9.7 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 GAP89628.1 - 0.17 11.1 0.3 0.3 10.3 0.3 1.3 1 0 0 1 1 1 0 Thi4 family PTR2 PF00854.21 GAP89630.1 - 4.5e-44 150.9 2.1 6.3e-44 150.4 2.1 1.1 1 0 0 1 1 1 1 POT family Ribonuclease PF00545.20 GAP89631.1 - 1.4e-08 35.4 0.1 1.9e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 ribonuclease GMC_oxred_N PF00732.19 GAP89632.1 - 1.3e-58 198.7 0.0 1.7e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP89632.1 - 1.3e-30 106.8 0.0 2.2e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAP89632.1 - 0.00039 19.6 0.1 0.00067 18.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAP89632.1 - 0.0021 18.3 0.0 0.0064 16.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAP89632.1 - 0.0043 16.3 0.1 0.0075 15.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family PROCN PF08083.11 GAP89634.1 - 4.7e-234 776.5 8.4 4.7e-234 776.5 8.4 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 GAP89634.1 - 4.8e-126 419.0 1.0 9.1e-126 418.1 1.0 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 GAP89634.1 - 1.1e-88 295.2 1.9 3.4e-88 293.6 1.9 2.0 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 GAP89634.1 - 4.5e-78 260.4 2.5 4.5e-78 260.4 2.5 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 GAP89634.1 - 1.4e-71 238.8 0.1 3.1e-71 237.7 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 GAP89634.1 - 2.4e-47 159.2 0.3 6.9e-47 157.7 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 GAP89634.1 - 1.7e-42 144.2 0.0 4.9e-42 142.7 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain Ribosomal_L34e PF01199.18 GAP89635.1 - 2.2e-43 146.5 1.8 3e-43 146.1 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 GAP89635.1 - 0.068 12.6 0.0 0.068 12.6 0.0 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain OrfB_Zn_ribbon PF07282.11 GAP89635.1 - 0.46 10.4 3.1 9.3 6.3 0.5 2.6 2 1 1 3 3 3 0 Putative transposase DNA-binding domain FhuF_C PF11575.8 GAP89635.1 - 8 6.5 7.5 10 6.2 0.2 2.9 2 1 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain DUF498 PF04430.14 GAP89636.1 - 9.3e-27 93.3 0.0 1.2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Abhydrolase_1 PF00561.20 GAP89637.1 - 1.3e-20 74.1 0.0 2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP89637.1 - 2e-17 64.6 2.2 2e-17 64.5 1.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP89637.1 - 1.7e-13 50.4 0.0 1.7e-12 47.1 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 GAP89637.1 - 5.1e-08 32.8 0.0 1.9e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 GAP89637.1 - 1.9e-05 24.9 0.1 3.6e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain PTPlike_phytase PF14566.6 GAP89637.1 - 0.00022 21.4 0.0 0.00044 20.4 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate LIDHydrolase PF10230.9 GAP89637.1 - 0.004 16.7 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 GAP89637.1 - 0.0081 15.9 0.2 0.5 10.1 0.1 2.2 2 0 0 2 2 2 1 PGAP1-like protein Y_phosphatase PF00102.27 GAP89637.1 - 0.0086 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LCAT PF02450.15 GAP89637.1 - 0.029 13.5 0.1 0.048 12.8 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase FSH1 PF03959.13 GAP89637.1 - 0.049 13.3 0.0 0.53 9.9 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ser_hydrolase PF06821.13 GAP89637.1 - 0.061 13.2 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase DUF900 PF05990.12 GAP89637.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Sad1_UNC PF07738.13 GAP89638.1 - 2.1e-30 105.4 0.0 3.6e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RRM_2 PF04059.12 GAP89639.1 - 3e-38 129.9 0.3 5e-38 129.2 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 GAP89639.1 - 0.16 11.8 0.0 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.12 GAP89641.1 - 8.9e-113 376.9 0.5 8.9e-113 376.9 0.5 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.6 GAP89641.1 - 0.0019 18.0 3.5 0.004 16.9 2.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF3510 PF12022.8 GAP89641.1 - 0.037 14.4 3.2 11 6.4 0.1 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF3510) COG5 PF10392.9 GAP89641.1 - 0.063 13.5 5.6 3.4 7.8 2.4 3.7 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 GAP89641.1 - 0.086 12.7 7.2 0.08 12.8 2.9 2.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Rnk_N PF14760.6 GAP89641.1 - 0.23 12.0 0.9 54 4.4 0.0 3.7 3 0 0 3 3 3 0 Rnk N-terminus BORCS8 PF10167.9 GAP89641.1 - 0.28 11.1 4.8 0.18 11.8 1.8 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 Hrs_helical PF12210.8 GAP89641.1 - 1.4 9.5 10.2 5.1 7.7 1.6 3.5 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TPR_MLP1_2 PF07926.12 GAP89641.1 - 1.4 9.0 9.4 1.9 8.6 4.1 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 GAP89641.1 - 1.5 8.9 13.0 0.68 10.0 4.0 3.9 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.10 GAP89641.1 - 2.7 8.2 7.2 14 6.0 2.4 3.4 3 0 0 3 3 3 0 Cortexillin I, coiled coil CBFD_NFYB_HMF PF00808.23 GAP89642.1 - 2.8e-19 69.2 0.5 3.8e-19 68.7 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAP89642.1 - 1.1e-14 55.0 0.2 1.7e-14 54.3 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 GAP89642.1 - 0.052 13.9 0.1 0.079 13.3 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.11 GAP89643.1 - 2.7e-36 123.8 0.3 8.2e-36 122.3 0.3 1.8 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Pex14_N PF04695.13 GAP89643.1 - 0.16 12.6 6.0 0.05 14.3 3.1 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ADH_zinc_N_2 PF13602.6 GAP89644.1 - 1e-08 36.3 0.0 1e-08 36.3 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAP89645.1 - 4.4e-08 33.2 0.5 7.3e-08 32.5 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP89645.1 - 0.00018 21.3 0.0 0.00036 20.4 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 GAP89645.1 - 0.035 13.4 0.6 0.06 12.6 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4054 PF13262.6 GAP89645.1 - 0.086 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Vps16_N PF04841.13 GAP89646.1 - 5.4e-95 318.6 0.0 9.2e-95 317.8 0.0 1.4 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 GAP89646.1 - 2e-84 283.4 0.0 2.8e-84 282.9 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 GAP89646.1 - 0.0004 20.6 0.0 0.18 12.1 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 GAP89647.1 - 3.8e-11 42.6 0.0 9e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.6 GAP89647.1 - 0.85 8.9 16.5 1.4 8.2 16.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mitofilin PF09731.9 GAP89647.1 - 2.8 6.7 29.9 4 6.1 29.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Asp-B-Hydro_N PF05279.11 GAP89647.1 - 8.2 6.4 22.5 17 5.4 22.5 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FTZ PF03867.14 GAP89648.1 - 0.4 10.2 5.1 0.63 9.5 5.1 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region SUIM_assoc PF16619.5 GAP89648.1 - 0.62 10.2 13.3 2 8.5 13.3 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4805 PF16063.5 GAP89648.1 - 1.1 8.5 6.4 0.54 9.5 4.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) DivIC PF04977.15 GAP89648.1 - 2.6 7.9 10.3 4.2 7.2 1.3 2.7 2 1 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.16 GAP89652.1 - 6.8e-22 77.9 63.5 2.2e-18 66.3 33.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cwf_Cwc_15 PF04889.12 GAP89653.1 - 3.5e-90 302.1 22.9 3.9e-90 301.9 22.9 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 GAP89653.1 - 0.054 12.9 24.4 0.064 12.7 24.4 1.1 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.10 GAP89653.1 - 0.63 9.4 17.4 0.85 8.9 17.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 GAP89653.1 - 0.86 7.8 22.3 0.98 7.6 22.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAP89653.1 - 1.3 7.2 25.3 1.4 7.0 25.3 1.1 1 0 0 1 1 1 0 Nop14-like family EMP24_GP25L PF01105.24 GAP89653.1 - 5.6 6.9 7.3 8.5 6.3 7.3 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Pet100 PF09803.9 GAP89653.1 - 6.1 7.4 5.9 15 6.2 5.9 1.6 1 0 0 1 1 1 0 Pet100 Rhabdo_ncap PF00945.18 GAP89653.1 - 6.3 5.6 8.5 8 5.2 8.5 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein SAPS PF04499.15 GAP89653.1 - 9.5 4.9 13.9 11 4.7 13.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EBP PF05241.12 GAP89654.1 - 2.6e-55 186.7 7.3 3.1e-55 186.4 7.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 GAP89654.1 - 0.029 14.8 8.0 0.041 14.3 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) DUF3995 PF13160.6 GAP89654.1 - 1.5 9.2 10.9 1 9.8 6.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) Zn_clus PF00172.18 GAP89655.1 - 1.6e-06 28.1 9.7 3.1e-06 27.2 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.11 GAP89657.1 - 5e-22 77.5 0.9 1e-21 76.5 0.9 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 GAP89657.1 - 2.2e-08 33.8 1.1 4.8e-08 32.7 1.1 1.6 1 0 0 1 1 1 1 Homeodomain Fungal_trans PF04082.18 GAP89658.1 - 1.6e-10 40.5 0.3 3e-10 39.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP89658.1 - 4.8e-09 36.2 10.0 8.1e-09 35.5 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rhodanese PF00581.20 GAP89659.1 - 1.2e-07 32.2 0.0 4.1e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Homeodomain PF00046.29 GAP89659.1 - 2.9e-07 30.2 0.6 1.6e-06 27.8 0.1 2.4 2 0 0 2 2 2 1 Homeodomain FAD_binding_6 PF00970.24 GAP89661.1 - 3.8e-30 104.1 0.0 6.1e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 GAP89661.1 - 2.2e-28 99.1 0.0 6.8e-28 97.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 GAP89661.1 - 0.00055 20.1 0.0 0.019 15.1 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF3605 PF12239.8 GAP89662.1 - 1.4e-54 184.6 0.0 1.7e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) TPR_1 PF00515.28 GAP89663.1 - 8.2e-39 129.9 21.4 6.9e-08 32.0 0.1 9.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAP89663.1 - 1.5e-36 121.5 33.3 2.9e-06 27.0 0.0 10.5 11 0 0 11 11 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP89663.1 - 1.6e-29 101.9 29.6 8.9e-23 80.3 0.3 6.3 4 1 3 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 GAP89663.1 - 1.9e-26 90.0 24.3 0.0018 18.4 0.0 10.1 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_12 PF13424.6 GAP89663.1 - 1.1e-21 76.9 22.5 0.001 19.3 0.5 8.2 6 2 1 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAP89663.1 - 1e-18 67.6 26.2 4.3e-08 33.6 4.6 7.2 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAP89663.1 - 1.5e-18 65.9 22.0 0.012 16.3 0.1 9.9 5 2 7 12 12 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAP89663.1 - 6.3e-17 61.0 23.2 1.2e-05 24.9 1.3 10.0 8 3 3 11 11 11 4 TPR repeat TPR_17 PF13431.6 GAP89663.1 - 1.9e-16 59.2 15.4 0.17 12.4 0.2 9.7 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 GAP89663.1 - 2.2e-16 60.2 32.4 1.4e-05 25.7 0.2 8.1 7 2 2 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAP89663.1 - 2.5e-12 45.9 14.4 0.038 14.0 0.0 8.5 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 GAP89663.1 - 8.8e-11 41.7 17.7 0.55 11.0 0.0 9.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAP89663.1 - 1.4e-08 34.8 13.0 0.0036 17.4 1.3 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAP89663.1 - 5.5e-06 25.8 13.9 0.091 12.0 4.7 4.7 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 GAP89663.1 - 0.0037 17.7 2.5 9.1 7.2 0.4 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Sel1 PF08238.12 GAP89663.1 - 0.0046 17.6 6.6 2.9 8.7 0.0 5.5 6 1 1 7 7 7 1 Sel1 repeat DUF2225 PF09986.9 GAP89663.1 - 0.018 14.8 6.5 2.2 8.0 1.1 3.9 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 GAP89663.1 - 0.081 12.8 0.2 0.081 12.8 0.2 5.8 6 1 1 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAP89663.1 - 0.34 11.0 11.4 0.62 10.2 0.2 5.7 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat CENP-T_C PF15511.6 GAP89664.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 GAP89664.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 GAP89664.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 GAP89664.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 GAP89664.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 GAP89664.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAP89664.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 GAP89664.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 GAP89664.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Sedlin_N PF04628.13 GAP89665.1 - 1.3e-42 145.1 0.0 1.5e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 GAP89665.1 - 0.021 14.8 0.0 0.27 11.2 0.0 2.1 1 1 0 2 2 2 0 Sybindin-like family RRM_1 PF00076.22 GAP89666.1 - 8e-16 57.6 0.0 1.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.9 GAP89667.1 - 0.0005 18.0 1.5 0.73 7.6 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore component DUF5082 PF16888.5 GAP89667.1 - 0.021 15.1 1.9 0.042 14.1 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DMPK_coil PF08826.10 GAP89667.1 - 0.021 14.9 0.4 0.1 12.8 0.4 2.1 1 0 0 1 1 1 0 DMPK coiled coil domain like Cep57_CLD PF14073.6 GAP89667.1 - 0.08 13.0 7.2 0.15 12.0 7.2 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 GldM_N PF12081.8 GAP89667.1 - 0.13 12.3 5.2 0.77 9.8 3.5 2.2 1 1 0 2 2 2 0 GldM N-terminal domain Con-6 PF10346.9 GAP89667.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Conidiation protein 6 UPF0242 PF06785.11 GAP89667.1 - 2 8.5 9.7 3.7 7.6 9.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 GAP89667.1 - 2.2 7.6 4.6 3.7 6.8 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3246 PF11596.8 GAP89668.1 - 0.084 12.3 8.8 0.3 10.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) CENP-B_dimeris PF09026.10 GAP89668.1 - 0.79 10.2 14.9 3.1 8.2 4.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TFIIE-A_C PF11521.8 GAP89668.1 - 5.5 7.4 7.9 6.6 7.1 0.7 2.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF4611 PF15387.6 GAP89668.1 - 5.9 7.2 8.9 18 5.7 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PI3_PI4_kinase PF00454.27 GAP89670.1 - 3.9e-33 115.3 0.0 4.7e-32 111.8 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 GAP89670.1 - 1.1e-18 67.0 0.0 2.6e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 MLD PF11647.8 GAP89670.1 - 0.14 12.5 0.0 7.4 6.9 0.0 3.1 3 0 0 3 3 3 0 Membrane Localization Domain PI3Ka PF00613.20 GAP89670.1 - 0.19 11.1 0.4 0.39 10.1 0.4 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CBFD_NFYB_HMF PF00808.23 GAP89671.1 - 8.5e-12 45.2 1.5 1.3e-11 44.5 1.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAP89671.1 - 0.0089 16.4 4.5 0.0089 16.4 4.5 2.5 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 GAP89671.1 - 1.1 9.4 4.0 0.33 11.1 0.4 1.9 2 0 0 2 2 2 0 hTAFII28-like protein conserved region FGGY_N PF00370.21 GAP89672.1 - 9.9e-21 74.4 0.0 8e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 GAP89672.1 - 8.1e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Cation_efflux PF01545.21 GAP89673.1 - 1.4e-51 175.0 7.0 2e-51 174.6 7.0 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 GAP89673.1 - 0.00029 20.9 0.1 0.00064 19.8 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter TFIIA PF03153.13 GAP89673.1 - 1 9.3 4.8 1.5 8.7 4.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MGC-24 PF05283.11 GAP89673.1 - 6.8 7.1 16.7 20 5.6 16.7 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SIR2 PF02146.17 GAP89674.1 - 5.4e-34 117.7 0.0 7.5e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF2529 PF10740.9 GAP89674.1 - 0.03 14.0 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) DUF5321 PF17254.2 GAP89675.1 - 8.7e-60 200.8 1.2 1.1e-59 200.4 1.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) RAMP4 PF06624.12 GAP89675.1 - 0.016 15.2 0.9 0.35 11.0 0.1 2.3 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Qua1 PF16274.5 GAP89675.1 - 0.063 13.1 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Qua1 domain APH PF01636.23 GAP89676.1 - 1.5e-15 57.8 0.0 9.1e-15 55.2 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP89676.1 - 0.0011 18.6 0.1 0.053 13.1 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 GAP89676.1 - 0.0015 17.8 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase OpuAC PF04069.12 GAP89676.1 - 0.084 12.4 0.3 0.16 11.5 0.3 1.5 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Pkinase PF00069.25 GAP89676.1 - 0.15 11.4 0.0 0.48 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain Peptidase_C50 PF03568.17 GAP89677.1 - 1.4e-157 524.9 0.0 4.6e-157 523.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 GAP89677.1 - 6.1e-05 23.2 26.4 0.2 12.0 0.2 8.4 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAP89677.1 - 0.00012 21.9 7.0 1 9.6 0.1 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat CHAT PF12770.7 GAP89677.1 - 0.00046 19.7 1.4 0.00046 19.7 1.4 3.6 3 1 0 3 3 3 1 CHAT domain TPR_4 PF07721.14 GAP89677.1 - 0.067 13.9 4.4 0.69 10.7 0.0 4.9 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAP89677.1 - 0.15 11.9 7.3 1.9 8.4 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAP89677.1 - 0.29 11.8 0.0 0.29 11.8 0.0 5.1 4 1 1 5 5 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP89677.1 - 0.31 11.3 11.6 1.4 9.2 0.0 5.1 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 GAP89677.1 - 0.45 10.2 6.8 5.9 6.6 0.1 4.5 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 GAP89677.1 - 0.79 9.7 2.9 9.8 6.2 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAP89677.1 - 2.1 9.4 14.9 1.8 9.6 0.2 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAP89677.1 - 3.6 8.0 10.4 42 4.7 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAP89677.1 - 4.9 7.7 21.2 1 9.9 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Arch_flagellin PF01917.16 GAP89678.1 - 0.038 14.2 2.4 0.047 13.9 2.4 1.1 1 0 0 1 1 1 0 Archaebacterial flagellin Fungal_trans PF04082.18 GAP89679.1 - 2.8e-25 88.9 0.0 4.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP89679.1 - 2.1e-09 37.4 10.9 3.3e-09 36.7 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kri1 PF05178.12 GAP89680.1 - 9.4e-28 96.8 17.8 9.4e-28 96.8 17.8 5.7 6 1 1 7 7 7 1 KRI1-like family Kri1_C PF12936.7 GAP89680.1 - 7e-27 93.4 0.1 7e-27 93.4 0.1 3.9 3 1 1 4 4 4 1 KRI1-like family C-terminal SSP160 PF06933.11 GAP89680.1 - 0.13 10.5 1.5 0.21 9.8 1.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ras PF00071.22 GAP89681.1 - 3.8e-58 195.7 0.0 4.4e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP89681.1 - 3.5e-34 117.6 0.0 5.1e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP89681.1 - 8.9e-14 51.3 0.0 1.5e-13 50.6 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 GAP89681.1 - 3.2e-05 23.6 0.0 5e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAP89681.1 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 GAP89681.1 - 0.00016 21.1 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 GAP89681.1 - 0.00086 19.7 0.0 0.0013 19.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAP89681.1 - 0.036 14.0 0.1 1.9 8.4 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase Glypican PF01153.19 GAP89681.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Glypican AAA_22 PF13401.6 GAP89681.1 - 0.13 12.5 0.0 0.84 9.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain zf-C3HC4_3 PF13920.6 GAP89682.1 - 0.0012 18.7 11.8 0.0018 18.1 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 GAP89682.1 - 0.0029 17.4 6.4 0.0047 16.8 6.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF4316 PF14195.6 GAP89682.1 - 0.018 14.7 1.3 0.057 13.2 1.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Prok-RING_4 PF14447.6 GAP89682.1 - 8.2 6.4 12.4 15 5.6 12.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAP89682.1 - 9 6.3 12.6 15 5.7 12.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain ABM PF03992.16 GAP89683.1 - 1.3e-10 41.2 1.1 1.4e-05 25.1 1.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF4054 PF13262.6 GAP89683.1 - 0.24 11.5 3.6 0.77 9.8 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4054) PIG-X PF08320.12 GAP89684.1 - 4.1e-69 232.7 0.0 8.4e-69 231.7 0.0 1.5 1 0 0 1 1 1 1 PIG-X / PBN1 FYRC PF05965.14 GAP89684.1 - 0.13 12.4 0.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 F/Y rich C-terminus 2OG-FeII_Oxy_3 PF13640.6 GAP89685.1 - 3.2e-09 37.6 0.0 5.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Collagen PF01391.18 GAP89686.1 - 0.0043 16.8 4.3 0.012 15.3 4.3 1.8 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Sulfotransfer_3 PF13469.6 GAP89686.1 - 0.11 12.9 0.1 7.4 6.9 0.0 2.9 3 1 0 3 3 3 0 Sulfotransferase family Mhr1 PF12829.7 GAP89687.1 - 2.7e-30 104.3 0.0 4.2e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination GoLoco PF02188.17 GAP89687.1 - 0.05 13.1 0.6 0.1 12.2 0.6 1.6 1 0 0 1 1 1 0 GoLoco motif AAA_2 PF07724.14 GAP89688.1 - 2.9e-47 161.0 0.0 1.6e-45 155.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 GAP89688.1 - 1e-34 118.6 9.9 5.9e-33 112.9 1.1 3.8 2 1 1 3 3 3 2 AAA lid domain AAA PF00004.29 GAP89688.1 - 3e-27 95.7 0.0 3.2e-14 53.5 0.0 3.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 GAP89688.1 - 2.1e-24 85.4 1.4 9e-24 83.3 1.4 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 GAP89688.1 - 4.7e-16 59.0 0.1 6.4e-10 39.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAP89688.1 - 5.2e-13 49.7 10.4 2.2e-06 28.1 0.1 5.6 5 2 0 6 6 4 2 AAA ATPase domain AAA_22 PF13401.6 GAP89688.1 - 8.9e-12 45.5 0.2 0.0005 20.4 0.0 4.3 3 2 0 3 3 2 2 AAA domain Clp_N PF02861.20 GAP89688.1 - 4.3e-11 42.8 0.7 5.4e-06 26.4 0.0 4.0 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 GAP89688.1 - 1.4e-09 37.9 0.0 5.6e-06 26.2 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 GAP89688.1 - 1.1e-06 28.7 0.0 0.073 13.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 GAP89688.1 - 7.3e-06 25.6 0.0 0.048 13.2 0.0 2.9 3 0 0 3 3 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAP89688.1 - 1e-05 25.0 0.2 0.28 10.5 0.2 3.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 GAP89688.1 - 1.8e-05 25.1 0.0 0.5 10.6 0.0 3.4 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 GAP89688.1 - 2.5e-05 24.1 0.0 0.23 11.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 GAP89688.1 - 6.3e-05 23.5 3.7 0.16 12.5 0.0 4.3 4 1 0 4 4 3 2 AAA domain AAA_30 PF13604.6 GAP89688.1 - 8.8e-05 22.3 0.0 0.59 9.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 GAP89688.1 - 0.0001 22.3 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 GAP89688.1 - 0.0001 22.1 0.0 0.96 9.3 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAP89688.1 - 0.00012 22.4 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 GAP89688.1 - 0.00014 22.0 0.1 0.61 10.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 GAP89688.1 - 0.00019 20.6 0.0 0.0048 16.0 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 GAP89688.1 - 0.0002 21.4 7.1 0.055 13.4 0.1 4.7 5 1 0 5 5 4 1 ATPase domain predominantly from Archaea RuvB_N PF05496.12 GAP89688.1 - 0.00022 21.0 1.9 4.2 7.1 0.8 4.5 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 GAP89688.1 - 0.00035 20.4 0.0 0.25 11.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 GAP89688.1 - 0.00079 19.8 1.0 0.21 11.9 0.1 3.5 4 1 0 4 4 2 1 AAA domain AAA_29 PF13555.6 GAP89688.1 - 0.0011 18.6 0.0 2 8.2 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.15 GAP89688.1 - 0.0014 18.7 0.0 0.52 10.3 0.0 4.0 4 1 0 4 4 3 1 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 GAP89688.1 - 0.0017 18.3 0.0 0.65 9.9 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 GAP89688.1 - 0.0017 18.9 0.2 2 8.9 0.0 3.1 3 0 0 3 3 2 1 ABC transporter Torsin PF06309.11 GAP89688.1 - 0.0024 18.0 0.0 0.014 15.5 0.0 2.1 2 0 0 2 2 2 1 Torsin NACHT PF05729.12 GAP89688.1 - 0.0029 17.5 0.0 0.45 10.4 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 GAP89688.1 - 0.0034 17.9 8.0 0.93 10.0 0.0 4.3 5 0 0 5 5 3 1 AAA domain NTPase_1 PF03266.15 GAP89688.1 - 0.0037 17.2 0.0 0.33 10.9 0.0 3.4 3 0 0 3 3 3 1 NTPase Zeta_toxin PF06414.12 GAP89688.1 - 0.0054 16.0 0.0 0.6 9.4 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 GAP89688.1 - 0.027 14.7 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 GAP89688.1 - 0.038 13.9 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 GAP89688.1 - 0.043 13.4 4.6 3 7.4 0.0 4.0 3 1 0 3 3 3 0 AAA domain Macoilin PF09726.9 GAP89688.1 - 0.046 12.3 7.3 0.073 11.6 7.3 1.2 1 0 0 1 1 1 0 Macoilin family CbiA PF01656.23 GAP89688.1 - 0.072 13.1 0.0 20 5.3 0.0 3.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 GAP89688.1 - 0.079 12.6 0.0 4.1 7.0 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4407 PF14362.6 GAP89688.1 - 0.22 10.9 11.2 0.48 9.7 11.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 GAP89688.1 - 0.25 9.2 1.6 0.4 8.5 1.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup88 PF10168.9 GAP89688.1 - 0.26 9.1 4.5 0.43 8.3 4.5 1.4 1 0 0 1 1 1 0 Nuclear pore component Cytidylate_kin PF02224.18 GAP89688.1 - 3.3 7.4 9.8 23 4.6 1.3 4.3 5 0 0 5 5 4 0 Cytidylate kinase CHDCT2 PF08074.11 GAP89688.1 - 9.4 6.4 7.5 2.2 8.4 0.1 3.4 4 1 1 5 5 3 0 CHDCT2 (NUC038) domain HD PF01966.22 GAP89689.1 - 0.002 18.4 0.1 0.0031 17.7 0.1 1.3 1 0 0 1 1 1 1 HD domain PrpF PF04303.13 GAP89690.1 - 9.8e-57 192.6 0.5 5.8e-37 127.5 0.6 3.5 2 1 0 2 2 2 2 PrpF protein TPR_2 PF07719.17 GAP89691.1 - 2.2e-25 86.7 20.4 0.013 15.5 0.0 11.7 13 0 0 13 13 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 GAP89691.1 - 8.6e-25 85.5 18.7 0.016 15.0 0.1 11.3 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_8 PF13181.6 GAP89691.1 - 1e-20 72.2 17.9 0.026 14.7 0.0 12.4 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_7 PF13176.6 GAP89691.1 - 1.1e-19 69.0 15.2 0.00015 21.6 0.1 10.6 10 1 0 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 GAP89691.1 - 2.2e-16 60.1 34.7 0.00031 21.2 0.4 11.3 10 2 2 12 12 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 GAP89691.1 - 8.2e-16 57.4 22.1 0.003 18.2 0.1 12.0 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAP89691.1 - 2e-15 56.8 20.3 0.0035 17.6 0.0 9.8 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 GAP89691.1 - 3.2e-12 46.3 19.4 0.00021 21.7 0.0 10.3 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAP89691.1 - 3.9e-12 46.6 17.2 0.014 16.1 0.3 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAP89691.1 - 7.9e-08 31.9 15.1 0.034 14.0 0.0 7.7 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAP89691.1 - 8.9e-08 31.7 17.4 0.67 9.7 0.1 8.9 10 1 1 11 11 10 3 TPR repeat ANAPC3 PF12895.7 GAP89691.1 - 3.1e-05 24.1 10.5 1.7 8.9 0.0 6.6 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 GAP89691.1 - 0.0001 22.4 20.9 2.1 8.9 0.2 11.3 15 0 0 15 15 12 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAP89691.1 - 0.025 14.6 2.8 4.4 7.4 0.1 4.4 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 GAP89691.1 - 0.042 12.8 0.0 0.042 12.8 0.0 6.5 6 2 2 8 8 6 0 NMDA receptor-regulated protein 1 DUF4810 PF16068.5 GAP89691.1 - 0.048 14.2 2.7 26 5.4 0.0 5.6 5 2 1 6 6 4 0 Domain of unknown function (DUF4810) PPR PF01535.20 GAP89691.1 - 0.069 13.4 0.0 53 4.4 0.0 3.9 3 0 0 3 3 3 0 PPR repeat TPR_4 PF07721.14 GAP89691.1 - 0.11 13.1 5.3 3 8.7 0.0 5.0 6 0 0 6 6 2 0 Tetratricopeptide repeat TFIIA PF03153.13 GAP89691.1 - 0.51 10.3 31.5 1.5 8.8 31.5 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NUDIX PF00293.28 GAP89692.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 GAP89693.1 - 4.9e-65 219.5 0.3 7.1e-65 219.0 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89693.1 - 1.1e-46 159.3 0.2 1.6e-46 158.7 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 GAP89693.1 - 4.7e-24 84.5 0.0 1.3e-23 83.1 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PH_11 PF15413.6 GAP89693.1 - 5e-07 30.1 0.1 1.1e-06 28.9 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 GAP89693.1 - 7.4e-07 28.8 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAP89693.1 - 3.4e-06 26.1 0.0 7.4e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 GAP89693.1 - 0.0021 18.5 0.1 0.006 17.1 0.1 1.8 1 0 0 1 1 1 1 PH domain Seadorna_VP7 PF07387.11 GAP89693.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 GAP89693.1 - 0.044 12.7 0.1 0.069 12.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 GAP89693.1 - 0.05 13.5 3.7 0.054 13.4 0.2 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 GAP89693.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Brix PF04427.18 GAP89694.1 - 3.1e-20 73.1 0.0 4.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Brix domain Nucleoside_tran PF01733.18 GAP89695.1 - 1.3e-41 143.0 8.3 1.2e-40 139.8 8.3 2.1 1 1 0 1 1 1 1 Nucleoside transporter Flu_M1_C PF08289.11 GAP89695.1 - 0.1 12.8 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain NfeD PF01957.18 GAP89695.1 - 0.59 10.5 1.9 2.5 8.5 0.3 2.5 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding E1-E2_ATPase PF00122.20 GAP89695.1 - 5 6.6 7.6 11 5.5 0.9 3.1 2 1 1 3 3 3 0 E1-E2 ATPase Ins_P5_2-kin PF06090.12 GAP89696.1 - 5.7e-37 127.9 0.0 1.8e-36 126.3 0.0 1.7 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase B3 PF02362.21 GAP89696.1 - 0.046 13.6 0.1 0.084 12.8 0.1 1.3 1 0 0 1 1 1 0 B3 DNA binding domain DUF4667 PF15700.5 GAP89697.1 - 0.014 15.5 4.4 0.014 15.5 4.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) SUZ PF12752.7 GAP89697.1 - 5.1 7.9 7.9 6.9 7.5 3.0 2.5 2 0 0 2 2 2 0 SUZ domain YEATS PF03366.16 GAP89698.1 - 1.1e-26 92.6 0.4 2.2e-26 91.6 0.4 1.5 1 1 0 1 1 1 1 YEATS family PEP-utilisers_N PF05524.13 GAP89698.1 - 0.035 14.3 0.4 0.059 13.6 0.4 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal NAD_binding_10 PF13460.6 GAP89699.1 - 5e-07 29.8 0.0 5e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP89699.1 - 3.8e-06 26.5 0.0 2e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAP89699.1 - 0.00024 20.2 0.0 0.0025 16.8 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 GAP89699.1 - 0.0067 15.6 0.0 0.065 12.3 0.0 2.4 3 0 0 3 3 3 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 GAP89699.1 - 0.019 14.1 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 GAP89699.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SYF2 PF08231.12 GAP89700.1 - 1.8e-55 187.7 11.8 1.8e-55 187.7 11.8 1.6 2 0 0 2 2 2 1 SYF2 splicing factor Ecl1 PF12855.7 GAP89703.1 - 4.3e-36 125.7 18.4 4.3e-36 125.7 18.4 1.5 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 GAP89703.1 - 0.031 14.4 1.4 0.054 13.6 1.4 1.3 1 0 0 1 1 1 0 MYND finger PLATZ PF04640.14 GAP89703.1 - 0.1 13.2 0.6 0.18 12.4 0.6 1.4 1 0 0 1 1 1 0 PLATZ transcription factor zf-FLZ PF04570.14 GAP89703.1 - 0.28 10.7 4.8 0.6 9.6 4.8 1.6 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 GAP89703.1 - 1 9.5 6.6 14 5.9 6.6 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) DLH PF01738.18 GAP89704.1 - 1e-13 51.3 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 GAP89704.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP89704.1 - 0.01 15.3 0.2 0.028 13.9 0.1 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 GAP89704.1 - 0.02 14.5 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Putative esterase APH PF01636.23 GAP89705.1 - 7.3e-05 22.8 0.0 0.00029 20.8 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Hemerythrin PF01814.23 GAP89705.1 - 0.18 12.4 0.0 0.43 11.2 0.0 1.6 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Trypan_PARP PF05887.11 GAP89705.1 - 1.2 9.2 5.0 1.9 8.5 5.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF16 PF01519.16 GAP89706.1 - 0.00065 20.2 0.2 0.0019 18.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function DUF16 CLZ PF16526.5 GAP89706.1 - 0.0026 18.1 3.6 2.6 8.4 0.2 3.9 4 1 1 5 5 4 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 GAP89706.1 - 0.003 18.0 0.5 0.0078 16.7 0.5 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 GAP89706.1 - 0.0069 16.4 0.8 0.016 15.2 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 GAP89706.1 - 0.0092 16.0 0.6 0.062 13.3 0.2 2.0 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XhlA PF10779.9 GAP89706.1 - 0.011 15.9 0.7 0.089 13.0 0.3 2.5 3 0 0 3 3 2 0 Haemolysin XhlA LPP PF04728.13 GAP89706.1 - 0.012 16.0 0.7 0.042 14.2 0.7 2.0 1 0 0 1 1 1 0 Lipoprotein leucine-zipper KASH_CCD PF14662.6 GAP89706.1 - 0.012 15.4 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 GAP89706.1 - 0.013 15.9 0.0 0.064 13.7 0.0 2.2 1 0 0 1 1 1 0 Cell division protein ZapB UvrA_DNA-bind PF17755.1 GAP89706.1 - 0.035 14.4 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 UvrA DNA-binding domain BLOC1_2 PF10046.9 GAP89706.1 - 0.042 14.2 3.6 0.16 12.3 1.3 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4164 PF13747.6 GAP89706.1 - 0.066 13.5 1.5 0.45 10.8 0.1 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4164) Prefoldin_2 PF01920.20 GAP89706.1 - 0.073 13.0 3.0 0.83 9.6 0.3 2.9 2 1 1 3 3 3 0 Prefoldin subunit TLE_N PF03920.15 GAP89706.1 - 0.08 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DUF3552 PF12072.8 GAP89706.1 - 0.094 12.1 1.0 0.2 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) RasGAP_C PF03836.15 GAP89706.1 - 0.094 12.9 4.9 2.5 8.2 1.0 2.4 2 0 0 2 2 2 0 RasGAP C-terminus Cnn_1N PF07989.11 GAP89706.1 - 0.095 12.9 0.4 0.26 11.5 0.0 1.8 2 0 0 2 2 1 0 Centrosomin N-terminal motif 1 EzrA PF06160.12 GAP89706.1 - 0.1 10.8 3.3 0.11 10.6 0.4 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF2730 PF10805.8 GAP89706.1 - 0.11 12.6 0.5 0.25 11.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DivIC PF04977.15 GAP89706.1 - 0.12 12.2 1.0 0.29 10.9 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF4795 PF16043.5 GAP89706.1 - 0.12 12.0 1.7 0.14 11.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Enkurin PF13864.6 GAP89706.1 - 0.13 12.7 3.8 7.3 7.1 0.1 2.8 3 0 0 3 3 2 0 Calmodulin-binding Allexi_40kDa PF05549.11 GAP89706.1 - 0.18 11.3 1.8 0.33 10.4 1.8 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein Tropomyosin_1 PF12718.7 GAP89706.1 - 0.25 11.5 1.8 4 7.6 0.1 2.5 2 0 0 2 2 2 0 Tropomyosin like DUF2205 PF10224.9 GAP89706.1 - 0.27 11.3 1.3 0.4 10.7 0.2 1.8 2 0 0 2 2 2 0 Short coiled-coil protein Uds1 PF15456.6 GAP89706.1 - 0.29 11.3 2.9 1.5 9.0 0.5 2.6 2 1 0 2 2 2 0 Up-regulated During Septation Syntaxin-6_N PF09177.11 GAP89706.1 - 0.53 10.9 5.5 0.41 11.2 0.5 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal TRPM_tetra PF16519.5 GAP89706.1 - 1.4 9.1 3.1 20 5.3 0.1 2.5 1 1 1 2 2 2 0 Tetramerisation domain of TRPM TPR_MLP1_2 PF07926.12 GAP89706.1 - 1.9 8.6 5.2 1.6 8.8 0.1 2.6 3 0 0 3 3 2 0 TPR/MLP1/MLP2-like protein Fmp27_WPPW PF10359.9 GAP89706.1 - 2.8 6.7 6.4 0.32 9.8 1.7 1.6 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Atg14 PF10186.9 GAP89706.1 - 3.2 6.8 10.6 0.21 10.6 1.8 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Use1 PF09753.9 GAP89706.1 - 6 6.5 9.6 0.32 10.7 0.9 2.4 2 1 0 2 2 2 0 Membrane fusion protein Use1 DUF4611 PF15387.6 GAP89707.1 - 4.2 7.6 29.0 4.1 7.7 11.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) TIP41 PF04176.13 GAP89708.1 - 2.5e-61 206.1 0.0 3.6e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family Glyco_hydro_18 PF00704.28 GAP89709.1 - 4.9e-20 72.5 1.6 3.1e-18 66.6 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 ThrE PF06738.12 GAP89710.1 - 1.7e-65 220.8 26.9 2.9e-63 213.4 5.7 2.7 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAP89710.1 - 1.5e-07 31.6 15.5 1.5e-07 31.6 15.5 2.4 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE CH PF00307.31 GAP89711.1 - 4.1e-12 46.3 0.0 6.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain NDUFA12 PF05071.16 GAP89712.1 - 7.3e-12 46.0 3.1 1.8e-11 44.7 3.1 1.9 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Sod_Fe_C PF02777.18 GAP89715.1 - 3.2e-35 120.4 0.1 6.1e-35 119.5 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAP89715.1 - 4.6e-33 113.5 3.2 7.7e-33 112.8 0.4 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Zn_clus PF00172.18 GAP89716.1 - 1.1e-09 38.2 5.2 2.3e-09 37.2 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP89716.1 - 0.003 16.6 0.0 0.012 14.7 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C2 PF00648.21 GAP89718.1 - 5.2e-59 199.7 0.9 1.7e-57 194.8 0.9 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease NicO PF03824.16 GAP89719.1 - 1.6e-66 224.6 5.8 2.8e-66 223.7 5.8 1.4 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF4229 PF14012.6 GAP89719.1 - 2.7 8.1 0.0 2.7 8.1 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) Sid-5 PF17204.3 GAP89719.1 - 4.3 7.6 0.0 4.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Sid-5 family ADH_zinc_N PF00107.26 GAP89720.1 - 6.4e-07 29.4 0.2 1.1e-06 28.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP89720.1 - 0.00067 19.5 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Tyrosinase PF00264.20 GAP89721.1 - 4e-46 158.1 1.0 5.2e-46 157.7 1.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Amidase PF01425.21 GAP89722.1 - 3.9e-91 306.3 0.0 2.4e-88 297.1 0.0 2.9 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 GAP89723.1 - 1.9e-29 102.7 29.1 1.9e-29 102.7 29.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 GAP89723.1 - 0.00026 20.4 16.1 0.00026 20.4 16.1 2.6 1 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Fungal_trans PF04082.18 GAP89724.1 - 2.2e-16 59.7 0.3 5e-16 58.5 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP89724.1 - 2.4e-07 30.7 10.8 5.3e-07 29.6 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.12 GAP89725.1 - 5.3e-126 421.6 0.1 7e-126 421.2 0.1 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF1324 PF07038.11 GAP89726.1 - 0.096 12.9 0.5 0.18 12.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) LTP_2 PF14368.6 GAP89726.1 - 0.17 12.0 3.6 0.15 12.2 2.6 1.6 1 1 1 2 2 2 0 Probable lipid transfer Peptidase_M35 PF02102.15 GAP89726.1 - 0.37 9.6 2.5 0.4 9.5 2.5 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Glyco_hydro_20 PF00728.22 GAP89727.1 - 2.2e-26 93.1 0.1 4.4e-20 72.4 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 GAP89727.1 - 1.5e-06 29.0 0.0 2.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RIO1 PF01163.22 GAP89728.1 - 8.3e-68 227.7 0.0 8.3e-68 227.7 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 GAP89728.1 - 0.0057 16.0 0.2 1.4 8.2 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP89728.1 - 0.013 15.5 0.2 0.32 10.9 0.2 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAP89728.1 - 0.071 11.9 0.1 0.071 11.9 0.1 2.0 2 0 0 2 2 2 0 Fungal protein kinase Peptidase_M14 PF00246.24 GAP89729.1 - 1.1e-72 245.4 0.0 1.3e-72 245.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Hamartin PF04388.12 GAP89730.1 - 0.75 8.4 7.0 0.81 8.3 7.0 1.1 1 0 0 1 1 1 0 Hamartin protein PPP4R2 PF09184.11 GAP89730.1 - 0.9 9.1 17.8 0.038 13.6 11.2 1.8 2 0 0 2 2 2 0 PPP4R2 NPR3 PF03666.13 GAP89730.1 - 5.9 5.6 6.3 7.7 5.2 6.3 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cofilin_ADF PF00241.20 GAP89731.1 - 0.014 15.2 0.0 0.051 13.4 0.0 1.9 2 0 0 2 2 2 0 Cofilin/tropomyosin-type actin-binding protein PP2C PF00481.21 GAP89734.1 - 2.1e-59 201.3 0.1 1.3e-49 169.2 0.1 3.2 2 1 0 2 2 2 2 Protein phosphatase 2C Snf7 PF03357.21 GAP89735.1 - 4.5e-35 120.8 22.1 1.4e-34 119.1 19.9 2.0 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 GAP89735.1 - 0.029 14.3 7.9 0.05 13.5 7.9 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway CCAP PF11105.8 GAP89735.1 - 0.072 13.0 0.4 0.072 13.0 0.4 1.7 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a DDE_Tnp_1 PF01609.21 GAP89735.1 - 0.084 12.5 3.6 0.11 12.1 3.6 1.1 1 0 0 1 1 1 0 Transposase DDE domain DUF2797 PF10977.8 GAP89735.1 - 0.23 11.3 3.1 0.22 11.4 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) Dynamin_N PF00350.23 GAP89736.1 - 1.3e-17 64.4 0.2 8.3e-17 61.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 GAP89736.1 - 3.3e-10 40.0 0.0 2.2e-09 37.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAP89736.1 - 1.1e-06 28.4 1.2 3.4e-05 23.5 1.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 GAP89736.1 - 0.0073 15.9 0.6 0.19 11.3 0.7 2.7 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.13 GAP89736.1 - 0.038 13.0 0.0 0.085 11.9 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 GAP89736.1 - 0.071 13.0 3.8 3.1 7.7 0.0 3.5 4 1 1 5 5 5 0 RsgA GTPase Roc PF08477.13 GAP89736.1 - 0.075 13.2 0.1 3.3 8.0 0.0 2.5 1 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 GAP89736.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FH2 PF02181.23 GAP89736.1 - 0.24 10.5 2.3 0.18 10.9 0.6 1.5 2 0 0 2 2 2 0 Formin Homology 2 Domain DivIVA PF05103.13 GAP89736.1 - 0.97 9.5 4.4 0.42 10.7 1.1 2.1 2 1 0 2 2 2 0 DivIVA protein LapA_dom PF06305.11 GAP89737.1 - 0.24 11.2 1.4 0.28 11.0 0.6 1.7 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain PPP4R2 PF09184.11 GAP89739.1 - 1.2 8.6 6.4 4.3 6.9 0.0 2.2 2 0 0 2 2 2 0 PPP4R2 EHN PF06441.12 GAP89741.1 - 3.2e-32 111.1 2.1 9.4e-32 109.6 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAP89741.1 - 8.3e-12 45.3 0.3 1.4e-11 44.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP89741.1 - 1.7e-05 25.5 1.7 6.8e-05 23.6 2.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family ADH_zinc_N PF00107.26 GAP89742.1 - 7.5e-05 22.7 0.3 0.00013 22.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase bZIP_1 PF00170.21 GAP89743.1 - 5.2e-06 26.5 6.6 9.6e-06 25.6 6.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF5595 PF18077.1 GAP89743.1 - 0.12 12.5 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DUF3890 PF13029.6 GAP89743.1 - 0.21 12.1 0.5 0.35 11.3 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) ASD2 PF08687.11 GAP89743.1 - 0.55 9.8 8.9 0.13 11.8 0.4 2.1 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Spt20 PF12090.8 GAP89743.1 - 9.1 5.8 20.5 0.21 11.2 12.7 2.1 2 0 0 2 2 2 0 Spt20 family Mit_KHE1 PF10173.9 GAP89743.1 - 9.2 6.3 10.2 1.2e+02 2.7 10.2 2.1 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF5423 PF17461.2 GAP89745.1 - 0.057 12.3 1.0 0.084 11.7 1.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Zn_clus PF00172.18 GAP89746.1 - 6.8e-08 32.5 10.8 6.8e-08 32.5 10.8 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chorion_2 PF03964.15 GAP89746.1 - 1.4 9.8 6.0 0.14 13.0 1.4 1.7 2 0 0 2 2 2 0 Chorion family 2 MFS_1 PF07690.16 GAP89747.1 - 8.4e-47 159.8 34.8 9.7e-47 159.6 34.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP89747.1 - 2.7e-15 56.2 8.5 2.7e-15 56.2 8.5 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 GAP89747.1 - 3.4e-05 22.3 3.5 8.5e-05 21.0 3.4 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 GAP89747.1 - 9.5e-05 21.0 4.1 0.00014 20.4 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2583 PF10762.9 GAP89747.1 - 0.07 13.6 0.6 0.07 13.6 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) p450 PF00067.22 GAP89748.1 - 1.3e-37 129.7 0.1 1.7e-37 129.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 GAP89749.1 - 6.8e-26 90.7 1.3 2.1e-25 89.1 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAP89749.1 - 0.001 19.1 0.2 0.0056 16.8 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like p450 PF00067.22 GAP89751.1 - 1.2e-48 166.0 0.0 1.6e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flagellin_C PF00700.21 GAP89751.1 - 0.087 13.2 0.4 1.2 9.5 0.5 2.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region polyprenyl_synt PF00348.17 GAP89752.1 - 3.7e-41 140.9 0.0 4.9e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.22 GAP89753.1 - 3.2e-41 141.5 0.0 4.3e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.21 GAP89754.1 - 8.9e-46 156.4 0.0 1e-45 156.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2722 PF10846.8 GAP89755.1 - 0.021 13.8 1.0 0.034 13.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF5401 PF17380.2 GAP89755.1 - 0.026 12.6 0.1 0.026 12.6 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5401) Spt20 PF12090.8 GAP89755.1 - 1 8.9 12.1 2.3 7.8 12.1 1.5 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 GAP89755.1 - 7.1 6.8 17.4 17 5.6 13.4 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF347 PF03988.12 GAP89756.1 - 0.047 13.9 0.3 0.047 13.9 0.3 2.8 3 1 0 3 3 3 0 Repeat of Unknown Function (DUF347) zf-C2H2 PF00096.26 GAP89757.1 - 1.5e-29 100.8 58.2 1.1e-05 25.6 0.3 10.4 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP89757.1 - 3.3e-19 67.9 53.6 0.041 14.7 0.5 10.9 11 0 0 11 11 11 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAP89757.1 - 2.5e-10 40.3 63.0 0.00041 20.6 0.2 10.8 11 1 0 11 11 11 6 Zinc-finger double domain FOXP-CC PF16159.5 GAP89757.1 - 2.6e-10 40.8 38.0 0.002 18.7 0.1 8.2 5 2 3 8 8 8 5 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 GAP89757.1 - 3.3e-07 30.4 29.9 0.074 13.4 0.4 7.9 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 GAP89757.1 - 0.0025 18.5 20.9 0.04 14.6 1.1 4.7 2 2 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 GAP89757.1 - 0.01 16.1 22.1 13 6.2 6.0 5.3 3 1 2 5 5 5 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 GAP89757.1 - 0.12 12.6 30.5 0.65 10.1 3.9 5.2 4 1 1 5 5 5 0 Aberrant zinc-finger zf-met PF12874.7 GAP89757.1 - 0.12 12.8 35.7 0.44 11.0 0.2 8.3 11 0 0 11 11 9 0 Zinc-finger of C2H2 type AKAP95 PF04988.12 GAP89757.1 - 0.22 11.8 7.3 4.7 7.4 1.0 3.7 3 1 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) zf_Hakai PF18408.1 GAP89757.1 - 0.52 10.1 0.0 0.52 10.1 0.0 7.0 9 0 0 9 9 9 0 C2H2 Hakai zinc finger domain zf-C2H2_11 PF16622.5 GAP89757.1 - 2.9 7.7 9.4 57 3.6 0.0 5.4 6 0 0 6 6 6 0 zinc-finger C2H2-type RNA_pol_Rpb6 PF01192.22 GAP89758.1 - 1.3e-17 63.4 0.1 2.6e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF3551 PF12071.8 GAP89759.1 - 0.038 14.0 0.7 0.09 12.8 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) Toxin_2 PF00451.19 GAP89759.1 - 0.43 10.9 3.4 6.2 7.2 0.8 2.6 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 Esterase PF00756.20 GAP89760.1 - 1.9e-47 162.1 0.0 2.6e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 GAP89760.1 - 6.5e-05 22.5 0.2 0.0002 20.9 0.0 1.8 2 1 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 GAP89760.1 - 0.002 17.4 0.1 0.0056 16.0 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 GAP89760.1 - 0.0033 16.9 0.1 0.7 9.3 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 GAP89760.1 - 0.099 11.5 0.0 0.56 9.1 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme Afi1 PF07792.12 GAP89761.1 - 8e-47 159.1 1.4 1.7e-46 158.0 1.4 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 GAP89761.1 - 8e-35 119.2 0.0 1.4e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 GAP89761.1 - 6.1e-07 28.5 0.1 0.035 12.8 0.1 3.7 3 1 1 4 4 4 2 Transport protein Avl9 DUF2794 PF10984.8 GAP89761.1 - 0.13 12.4 0.1 0.35 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2794) DUF1168 PF06658.12 GAP89761.1 - 0.16 11.7 9.5 0.35 10.7 9.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Cwf_Cwc_15 PF04889.12 GAP89761.1 - 0.38 10.4 15.2 0.98 9.1 15.2 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 GAP89761.1 - 0.51 10.3 8.7 0.9 9.5 8.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 GAP89761.1 - 7 4.7 11.1 10 4.2 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family AMP-binding PF00501.28 GAP89762.1 - 2.9e-77 260.1 0.0 6.9e-77 258.8 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 GAP89762.1 - 1.7e-75 253.9 0.0 3.8e-75 252.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP89762.1 - 6.2e-59 198.9 0.0 1.5e-52 178.1 0.0 2.7 2 0 0 2 2 2 2 KR domain Condensation PF00668.20 GAP89762.1 - 3.7e-52 177.5 0.3 6.4e-52 176.7 0.3 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 GAP89762.1 - 1.6e-46 158.9 0.0 3e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP89762.1 - 3.5e-39 135.2 0.1 6.6e-39 134.3 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP89762.1 - 2.3e-29 101.8 0.0 7e-29 100.2 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 GAP89762.1 - 1.5e-27 96.4 0.0 1.2e-24 86.9 0.0 2.6 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 GAP89762.1 - 3.6e-21 75.7 0.0 5.2e-20 72.0 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 GAP89762.1 - 8.6e-17 61.3 1.1 6.2e-07 29.7 0.4 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAP89762.1 - 2.9e-16 59.9 0.0 1.1e-15 58.0 0.0 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAP89762.1 - 3.4e-14 52.8 0.1 2.1e-10 40.4 0.1 3.0 3 0 0 3 3 3 2 short chain dehydrogenase Methyltransf_25 PF13649.6 GAP89762.1 - 3.4e-13 50.1 0.0 1.8e-12 47.8 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP89762.1 - 4.2e-12 46.2 0.0 1.2e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP89762.1 - 9.6e-12 45.4 0.0 4.7e-11 43.2 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 GAP89762.1 - 1.2e-08 34.7 0.0 1e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.18 GAP89762.1 - 3.3e-07 29.9 0.0 8e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 GAP89762.1 - 1.5e-06 28.0 1.0 7.8e-06 25.6 0.0 2.7 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 GAP89762.1 - 1.5e-06 28.1 0.0 5e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.6 GAP89762.1 - 2.4e-06 28.4 0.1 6.7e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 GAP89762.1 - 7.8e-06 25.4 0.1 1.5e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 GAP89762.1 - 0.0046 16.4 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF938 PF06080.12 GAP89762.1 - 0.014 15.2 0.1 0.076 12.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF938) NAD_binding_10 PF13460.6 GAP89762.1 - 0.02 14.8 0.0 0.073 13.0 0.0 2.0 2 0 0 2 2 1 0 NAD(P)H-binding RrnaAD PF00398.20 GAP89762.1 - 0.033 13.2 0.1 0.18 10.8 0.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 GAP89762.1 - 0.037 13.8 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Polysacc_synt_2 PF02719.15 GAP89762.1 - 0.059 12.5 0.0 0.52 9.4 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 GAP89762.1 - 0.13 12.7 0.1 0.97 9.9 0.0 2.5 3 0 0 3 3 2 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.18 GAP89763.1 - 3.3e-14 52.5 0.0 5.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 GAP89764.1 - 6.4e-46 156.9 39.4 6.4e-46 156.9 39.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP89764.1 - 7.9e-08 31.6 34.4 5.3e-07 28.9 33.9 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 GAP89764.1 - 9.7e-07 28.4 7.5 9.7e-07 28.4 7.5 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Zn_clus PF00172.18 GAP89765.1 - 8.2e-05 22.6 12.3 0.00016 21.7 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_4 PF13637.6 GAP89766.1 - 4.1e-06 27.2 0.5 0.16 12.6 0.0 4.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP89766.1 - 2.2e-05 25.0 0.0 0.2 12.2 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP89766.1 - 0.00037 20.7 0.3 4.8 8.1 0.1 4.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 GAP89766.1 - 0.033 14.5 0.1 0.43 11.0 0.1 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Dioxygenase_C PF00775.21 GAP89768.1 - 3.7e-09 36.3 0.9 8.5e-09 35.1 0.2 1.9 2 1 0 2 2 2 1 Dioxygenase MccV PF17508.2 GAP89768.1 - 0.02 15.4 0.0 2.9 8.5 0.0 2.8 2 0 0 2 2 2 0 Microcin V bacteriocin zf-C2H2 PF00096.26 GAP89769.1 - 0.002 18.5 5.4 0.0048 17.3 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP89769.1 - 0.015 16.1 5.1 0.039 14.8 5.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger PNP_UDP_1 PF01048.20 GAP89770.1 - 3.7e-12 46.0 0.1 1.4e-11 44.2 0.1 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily AAA PF00004.29 GAP89771.1 - 1.4e-17 64.4 0.0 4e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP89771.1 - 0.00097 19.6 0.1 0.0047 17.3 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP89771.1 - 0.01 16.1 4.2 0.012 15.9 0.1 2.9 3 1 1 4 4 4 0 AAA domain AAA_5 PF07728.14 GAP89771.1 - 0.02 14.9 0.1 0.066 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 GAP89771.1 - 0.028 14.1 0.2 0.072 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 GAP89771.1 - 0.035 14.5 0.5 0.14 12.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain VWA_2 PF13519.6 GAP89771.1 - 0.052 14.2 0.1 0.17 12.6 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain AAA_11 PF13086.6 GAP89771.1 - 0.11 12.2 0.1 0.35 10.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 GAP89771.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 GAP89771.1 - 0.21 11.3 0.9 3 7.5 0.1 2.2 1 1 1 2 2 2 0 AAA domain Mtc PF03820.17 GAP89772.1 - 7.3e-117 389.9 0.0 8.2e-117 389.7 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF4507 PF14964.6 GAP89772.1 - 0.17 10.7 0.2 0.44 9.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4507) Pkinase PF00069.25 GAP89773.1 - 7.5e-50 169.7 0.0 1.4e-49 168.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89773.1 - 8.6e-20 71.1 0.0 2.5e-19 69.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Trypan_PARP PF05887.11 GAP89773.1 - 0.044 13.8 6.0 0.12 12.3 6.0 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Lactamase_B_2 PF12706.7 GAP89776.1 - 2.5e-13 50.0 0.6 4.6e-12 45.9 0.2 2.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain DUF2188 PF09954.9 GAP89776.1 - 0.024 14.8 0.2 0.08 13.1 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Lactamase_B PF00753.27 GAP89776.1 - 0.035 14.1 0.1 0.082 12.9 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 GAP89777.1 - 6.7e-28 96.2 0.0 1.5e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Glyco_hydro_16 PF00722.21 GAP89778.1 - 6.2e-08 32.3 0.5 1.3e-07 31.2 0.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 C1-set PF07654.15 GAP89778.1 - 0.07 13.5 0.1 0.26 11.7 0.0 1.9 1 1 0 1 1 1 0 Immunoglobulin C1-set domain Zn_clus PF00172.18 GAP89779.1 - 1.3e-08 34.8 9.6 1.9e-08 34.3 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FTZ PF03867.14 GAP89779.1 - 0.0076 15.8 2.3 0.083 12.4 0.7 2.4 2 0 0 2 2 2 1 Fushi tarazu (FTZ), N-terminal region SUIM_assoc PF16619.5 GAP89779.1 - 0.023 14.7 2.9 0.023 14.7 2.9 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Opy2 PF09463.10 GAP89779.1 - 0.14 12.5 2.2 0.32 11.4 2.2 1.5 1 0 0 1 1 1 0 Opy2 protein HET PF06985.11 GAP89780.1 - 2.1e-06 28.2 0.2 3.6e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 GAP89781.1 - 4.8e-120 392.4 18.0 8.1e-12 45.6 0.1 15.2 3 2 12 16 16 16 16 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP89781.1 - 1.3e-85 280.7 30.4 1.9e-09 37.9 0.0 21.8 10 5 12 23 23 23 20 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP89781.1 - 3.1e-75 239.1 18.6 3e-05 24.1 0.0 29.0 31 0 0 31 31 31 15 Ankyrin repeat Ank_5 PF13857.6 GAP89781.1 - 5.7e-75 246.4 28.2 2e-07 31.2 0.0 21.3 12 7 11 24 24 24 15 Ankyrin repeats (many copies) Ank PF00023.30 GAP89781.1 - 4.9e-53 175.4 50.4 4e-06 27.0 0.2 24.2 25 0 0 25 25 25 11 Ankyrin repeat adh_short PF00106.25 GAP89781.1 - 4.7e-19 68.6 1.4 7.5e-18 64.7 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase SPRY PF00622.28 GAP89781.1 - 1.5e-18 67.0 0.1 3.4e-18 65.9 0.1 1.6 1 0 0 1 1 1 1 SPRY domain KR PF08659.10 GAP89781.1 - 1.4e-06 28.3 0.6 6e-06 26.3 0.1 2.1 2 0 0 2 2 2 1 KR domain DUF3447 PF11929.8 GAP89781.1 - 0.11 12.4 0.0 29 4.7 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF3447) Pkinase_fungal PF17667.1 GAP89782.1 - 7.1e-136 453.2 0.0 8.6e-136 452.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 GAP89782.1 - 2.5e-06 27.0 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 GAP89782.1 - 0.037 13.4 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP89782.1 - 0.079 12.9 0.1 0.27 11.1 0.0 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family zf-C2H2_4 PF13894.6 GAP89784.1 - 0.95 10.5 13.9 1.5 9.8 0.0 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-Di19 PF05605.12 GAP89784.1 - 9.3 6.6 11.6 2.8 8.3 0.2 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Flavin_Reduct PF01613.18 GAP89786.1 - 1.2e-16 61.1 0.8 4.3e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 Flavin reductase like domain Ribosomal_60s PF00428.19 GAP89786.1 - 0.06 13.9 3.1 0.2 12.2 3.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein HET PF06985.11 GAP89787.1 - 1.6e-26 93.4 0.0 2.9e-24 86.1 0.0 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HAUS4 PF14735.6 GAP89787.1 - 0.2 11.4 0.1 0.31 10.7 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 PDEase_II PF02112.15 GAP89788.1 - 2.6e-54 184.6 0.0 1.9e-46 158.7 0.0 2.9 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 GAP89788.1 - 0.051 13.1 0.4 0.21 11.1 0.4 2.1 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Aldose_epim PF01263.20 GAP89789.1 - 0.085 12.1 0.0 0.39 10.0 0.0 1.8 1 1 1 2 2 2 0 Aldose 1-epimerase AMP-binding PF00501.28 GAP89790.1 - 7e-68 229.1 0.1 1.5e-25 89.7 0.0 4.6 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.11 GAP89790.1 - 4.3e-10 40.4 0.2 1.2e-09 38.9 0.2 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 GAP89790.1 - 0.00055 19.9 2.7 0.0012 18.8 2.7 1.5 1 0 0 1 1 1 1 Gas vesicle protein G Metallophos PF00149.28 GAP89791.1 - 1.3e-17 65.0 0.0 2.2e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 GAP89791.1 - 4.8e-11 43.4 0.0 1e-10 42.3 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 GAP89791.1 - 1.3e-07 32.0 0.1 2.3e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD PF09423.10 GAP89791.1 - 0.019 14.0 0.0 0.9 8.5 0.0 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase PhoD_N PF16655.5 GAP89791.1 - 0.11 13.1 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Metallophos_2 PF12850.7 GAP89791.1 - 0.2 11.8 0.0 3 8.0 0.0 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Arf PF00025.21 GAP89792.1 - 1.2e-73 246.3 0.0 1.3e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAP89792.1 - 1.7e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAP89792.1 - 7.6e-13 48.3 0.0 9.3e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 GAP89792.1 - 1.2e-11 44.4 0.3 1.2e-07 31.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 GAP89792.1 - 2.8e-11 43.3 0.0 3.3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 GAP89792.1 - 5.2e-08 32.5 0.0 6.7e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAP89792.1 - 1.7e-06 28.1 0.0 2.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAP89792.1 - 0.00036 20.1 0.1 0.028 13.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAP89792.1 - 0.0025 16.8 0.4 0.0065 15.5 0.2 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 GAP89792.1 - 0.0054 16.3 0.4 0.022 14.3 0.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Skp1 PF01466.19 GAP89793.1 - 1.6e-29 101.8 0.4 3.4e-29 100.7 0.4 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 GAP89793.1 - 8e-23 80.4 0.7 1.7e-22 79.4 0.4 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Trnau1ap PF17654.1 GAP89793.1 - 0.028 15.3 0.1 0.039 14.8 0.1 1.3 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins DUF4203 PF13886.6 GAP89794.1 - 1.6e-49 168.3 25.4 2.1e-49 167.9 25.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) OATP PF03137.20 GAP89794.1 - 0.032 12.5 0.0 0.055 11.8 0.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2613 PF11021.8 GAP89794.1 - 0.68 10.1 3.9 5.3 7.2 3.9 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) CCDC-167 PF15188.6 GAP89795.1 - 0.23 11.8 2.4 0.63 10.4 2.2 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 PilJ PF13675.6 GAP89795.1 - 0.42 10.6 5.3 0.12 12.4 1.6 2.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Erf4 PF10256.9 GAP89796.1 - 5.1e-38 129.7 0.0 7.4e-38 129.2 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family STE3 PF02076.15 GAP89798.1 - 2.2e-65 220.8 15.6 2.6e-65 220.5 15.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4281 PF14108.6 GAP89798.1 - 0.11 12.9 2.1 0.96 9.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) MFS_1 PF07690.16 GAP89799.1 - 4.2e-18 65.4 19.3 4.2e-18 65.4 19.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Prp18 PF02840.15 GAP89799.1 - 0.079 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Prp18 domain RINGv PF12906.7 GAP89800.1 - 8.6e-17 61.0 8.8 1.5e-16 60.3 8.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 GAP89800.1 - 0.0063 16.8 9.1 0.011 16.1 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 GAP89800.1 - 0.15 12.1 2.7 0.34 11.0 2.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAP89800.1 - 1.3 8.9 6.6 2.3 8.1 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Med11 PF10280.9 GAP89801.1 - 0.017 15.6 1.5 9.8 6.6 0.5 3.0 2 0 0 2 2 2 0 Mediator complex protein MFS_1 PF07690.16 GAP89803.1 - 1.3e-24 86.8 22.1 1.3e-24 86.8 22.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily HlyIII PF03006.20 GAP89803.1 - 1.6 8.4 12.0 0.15 11.8 1.2 2.5 2 0 0 2 2 2 0 Haemolysin-III related Amidohydro_1 PF01979.20 GAP89804.1 - 0.00018 20.9 0.2 0.08 12.2 0.4 2.2 1 1 0 2 2 2 2 Amidohydrolase family DUF3844 PF12955.7 GAP89804.1 - 0.46 10.6 2.1 0.7 10.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) SLATT_5 PF18160.1 GAP89804.1 - 2.7 7.3 8.0 8.7 5.6 1.3 2.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Glyco_hydro_16 PF00722.21 GAP89805.1 - 5e-11 42.4 0.1 1.4e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HET PF06985.11 GAP89805.1 - 0.001 19.5 1.0 0.047 14.0 1.0 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.19 GAP89806.1 - 1.3e-60 205.3 0.0 1.7e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP89806.1 - 3.7e-32 111.8 0.0 6.2e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 GAP89806.1 - 1.6e-08 34.5 0.5 6.8e-06 25.9 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAP89806.1 - 1.3e-06 27.7 0.3 4.2e-05 22.8 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAP89806.1 - 7.5e-05 22.9 0.3 0.00023 21.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAP89806.1 - 0.0017 17.5 0.0 0.31 10.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAP89806.1 - 0.0034 16.7 0.0 0.22 10.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP89806.1 - 0.016 15.7 0.0 0.55 10.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP89806.1 - 0.049 12.7 0.0 3 6.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A BolA PF01722.18 GAP89807.1 - 0.0049 17.1 0.1 0.0087 16.3 0.1 1.3 1 0 0 1 1 1 1 BolA-like protein 2-oxoacid_dh PF00198.23 GAP89808.1 - 1e-69 234.5 0.4 8.7e-69 231.5 0.2 2.3 2 1 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 GAP89808.1 - 1.5e-17 63.1 1.6 3e-17 62.2 1.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 GAP89808.1 - 0.004 17.8 0.3 3.2 8.5 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 GAP89808.1 - 0.022 14.6 0.2 0.65 9.9 0.1 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like DUF1854 PF08909.11 GAP89808.1 - 0.035 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) Trypan_PARP PF05887.11 GAP89808.1 - 1.5 8.8 15.6 2.7 8.0 15.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ndc1_Nup PF09531.10 GAP89808.1 - 5 5.7 6.4 6.4 5.3 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Complex1_LYR PF05347.15 GAP89809.1 - 3e-09 36.8 1.8 4.1e-09 36.4 1.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histone_H2A_C PF16211.5 GAP89810.1 - 3.1e-21 74.8 3.1 5.5e-21 74.0 3.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 GAP89810.1 - 3.2e-17 63.1 0.0 4.3e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAP89810.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 GAP89811.1 - 6.7e-21 75.0 2.0 8.4e-21 74.7 2.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 GAP89811.1 - 3.8e-05 23.9 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 GAP89811.1 - 0.00025 21.5 0.0 0.00042 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 GAP89811.1 - 0.038 13.6 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain R3H PF01424.22 GAP89812.1 - 2.5e-11 43.4 0.0 6.2e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 GAP89812.1 - 8.3e-10 38.4 1.0 2.1e-09 37.1 1.0 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 GAP89812.1 - 1.4e-05 25.0 0.2 9.7e-05 22.4 0.2 2.4 2 0 0 2 2 2 1 G-patch domain Peptidase_C54 PF03416.19 GAP89813.1 - 2.9e-94 315.6 0.0 3.6e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.31 GAP89814.1 - 5.3e-25 87.3 0.7 5.3e-25 87.3 0.7 2.2 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 GAP89814.1 - 3.6e-10 39.9 4.8 2.6e-09 37.1 3.7 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP89814.1 - 1e-07 32.1 3.8 1.7e-07 31.4 2.6 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAP89814.1 - 6.3e-06 26.5 4.6 0.00055 20.2 2.2 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 GAP89814.1 - 2.5e-05 24.7 2.8 0.06 14.2 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger RPT PF13446.6 GAP89814.1 - 0.0006 19.7 0.1 0.026 14.4 0.1 3.0 2 0 0 2 2 2 1 A repeated domain in UCH-protein zf-C2H2 PF00096.26 GAP89814.1 - 0.0064 16.9 4.2 0.15 12.6 0.7 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type Actin_micro PF17003.5 GAP89814.1 - 0.018 14.3 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative actin-like family DUF4674 PF15719.5 GAP89814.1 - 0.19 11.8 6.9 0.043 13.9 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) PTS_IIB PF02302.17 GAP89814.1 - 0.5 11.1 2.8 0.66 10.7 0.3 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit zf-C2H2_6 PF13912.6 GAP89814.1 - 5.9 7.0 6.1 1.3 9.1 2.8 1.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2256 PF10013.9 GAP89814.1 - 7.5 6.8 6.1 14 5.9 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) SPX PF03105.19 GAP89815.1 - 1.2e-43 150.5 0.0 1.8e-43 150.0 0.0 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 GAP89815.1 - 2.7e-07 30.3 7.5 5.1e-07 29.4 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP89815.1 - 3.6e-07 29.9 10.2 7.1e-07 29.0 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP89815.1 - 6e-07 29.2 9.6 6e-07 29.2 9.6 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP89815.1 - 4.8e-06 26.5 7.0 1e-05 25.5 7.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAP89815.1 - 5.8e-06 26.5 10.7 1.3e-05 25.5 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAP89815.1 - 1.8e-05 24.6 9.5 5.7e-05 23.0 9.6 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAP89815.1 - 2.2e-05 24.5 9.0 2.2e-05 24.5 9.0 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 GAP89815.1 - 0.018 14.9 11.3 0.15 11.9 11.9 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 GAP89815.1 - 0.091 12.6 3.7 0.15 12.0 2.6 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 GAP89815.1 - 0.2 11.7 2.2 0.44 10.6 2.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAP89815.1 - 0.21 11.4 8.9 0.042 13.6 4.8 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 GAP89815.1 - 1 9.7 10.9 3.3 8.1 10.9 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain AAA_30 PF13604.6 GAP89816.1 - 0.11 12.1 0.3 0.34 10.6 0.0 1.9 3 0 0 3 3 3 0 AAA domain PDZ_assoc PF10600.9 GAP89817.1 - 0.043 14.6 0.8 2.4 9.1 0.0 2.6 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors COG6 PF06419.11 GAP89818.1 - 9.1e-213 708.0 0.0 1e-212 707.8 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 GAP89818.1 - 0.0022 18.1 2.6 0.0091 16.1 1.1 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec34 PF04136.15 GAP89818.1 - 0.33 10.8 5.8 0.49 10.3 1.4 2.8 1 1 1 2 2 2 0 Sec34-like family DUF1043 PF06295.12 GAP89818.1 - 0.57 10.2 7.9 0.62 10.1 1.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) DASH_Dad4 PF08650.10 GAP89818.1 - 5 7.2 6.7 0.61 10.1 0.6 2.5 3 0 0 3 3 3 0 DASH complex subunit Dad4 APG9 PF04109.16 GAP89819.1 - 2.4e-187 623.7 10.0 2.9e-187 623.5 10.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Mito_carr PF00153.27 GAP89820.1 - 1.6e-65 217.1 7.9 1.1e-21 76.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAP89820.1 - 0.0081 15.3 5.2 0.36 9.9 0.5 2.7 1 1 1 2 2 2 2 Gammaproteobacterial serine protease Bac_export_2 PF01312.19 GAP89820.1 - 0.038 13.2 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Methyltransf_9 PF08003.11 GAP89820.1 - 0.21 10.5 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DnaJ PF00226.31 GAP89821.1 - 2.2e-20 72.5 0.8 2.2e-20 72.5 0.8 2.7 3 0 0 3 3 3 1 DnaJ domain TPR_9 PF13371.6 GAP89821.1 - 8.2e-12 45.1 0.3 0.00029 20.9 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAP89821.1 - 1.3e-11 43.8 0.0 0.0021 17.8 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP89821.1 - 1.4e-11 43.7 0.2 0.032 14.4 0.0 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAP89821.1 - 5.8e-10 38.5 4.1 0.064 13.4 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAP89821.1 - 1.5e-08 34.7 2.4 0.04 14.7 0.1 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAP89821.1 - 1.4e-07 31.9 1.8 0.025 15.1 0.0 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAP89821.1 - 5.2e-06 26.0 0.0 0.02 14.6 0.0 3.8 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 GAP89821.1 - 1.1e-05 26.0 1.2 0.64 10.7 0.0 4.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAP89821.1 - 1.5e-05 25.0 0.9 0.0013 18.9 0.0 4.0 4 0 0 4 4 2 1 Tetratricopeptide repeat PknG_TPR PF16918.5 GAP89821.1 - 1.9e-05 23.6 0.0 0.028 13.2 0.0 2.7 1 1 0 2 2 2 2 Protein kinase G tetratricopeptide repeat TPR_6 PF13174.6 GAP89821.1 - 0.00011 22.7 10.0 2.5 8.9 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAP89821.1 - 0.00047 20.0 0.1 0.13 12.4 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP89821.1 - 0.001 19.3 10.1 2.5 8.4 0.1 5.1 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAP89821.1 - 0.0032 17.7 7.4 0.026 14.8 0.1 4.2 4 2 1 5 5 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 GAP89821.1 - 0.018 15.1 0.7 3.7 7.6 0.1 4.2 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) DUF1217 PF06748.12 GAP89821.1 - 0.15 12.1 1.5 1 9.4 1.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) TPR_4 PF07721.14 GAP89821.1 - 2.2 9.1 5.1 6.8 7.6 1.8 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 GAP89821.1 - 2.2 8.7 5.0 21 5.6 0.0 3.4 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation PCRF PF03462.18 GAP89821.1 - 2.4 8.0 7.2 0.4 10.5 0.3 2.8 3 0 0 3 3 3 0 PCRF domain TPR_10 PF13374.6 GAP89821.1 - 9.9 6.2 7.6 5.5 7.0 0.1 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Vac14_Fig4_bd PF11916.8 GAP89824.1 - 1.3e-81 272.5 9.0 4e-81 270.9 8.5 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 GAP89824.1 - 1.2e-43 147.6 0.0 8.3e-42 141.7 0.0 3.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 GAP89824.1 - 2.5e-07 30.3 0.7 0.0019 18.3 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 GAP89824.1 - 1.9e-06 28.3 7.1 0.0059 17.1 0.1 4.9 6 0 0 6 6 6 2 HEAT-like repeat Cnd1 PF12717.7 GAP89824.1 - 2.5e-05 24.4 2.0 0.019 15.0 0.3 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAP89824.1 - 0.0013 19.1 0.5 1.4 9.4 0.0 4.4 4 1 0 4 4 4 1 HEAT repeats Arm PF00514.23 GAP89824.1 - 0.13 12.3 0.0 24 5.1 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat FA_desaturase PF00487.24 GAP89825.1 - 7.5e-25 88.2 27.3 1.4e-24 87.3 27.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAP89825.1 - 1.4e-07 31.5 0.0 2.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA PF00004.29 GAP89826.1 - 8.6e-39 133.0 0.0 2.4e-38 131.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAP89826.1 - 1.9e-08 34.0 0.0 4.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 GAP89826.1 - 4.3e-08 33.0 0.0 2.9e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 GAP89826.1 - 3e-05 23.8 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAP89826.1 - 6.1e-05 23.3 1.5 0.0011 19.2 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 GAP89826.1 - 9.8e-05 22.8 0.5 0.0052 17.2 0.2 3.1 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 GAP89826.1 - 0.00049 19.4 0.0 0.00088 18.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 GAP89826.1 - 0.0017 18.5 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAP89826.1 - 0.0018 18.3 0.0 0.0071 16.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAP89826.1 - 0.002 17.9 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAP89826.1 - 0.0046 16.4 0.1 0.0092 15.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 GAP89826.1 - 0.02 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 GAP89826.1 - 0.022 14.9 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 GAP89826.1 - 0.035 14.1 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAP89826.1 - 0.04 14.5 0.0 0.091 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 GAP89826.1 - 0.093 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 GAP89826.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAP89826.1 - 0.1 12.1 0.3 0.48 10.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 GAP89826.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CAP_N PF01213.19 GAP89827.1 - 2.2 7.7 18.2 0.086 12.3 10.6 2.5 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal EMG1 PF03587.14 GAP89828.1 - 1.1e-78 263.4 0.0 1.3e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyco_hydro_25 PF01183.20 GAP89829.1 - 2.2e-41 142.0 0.0 2.5e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 EamA PF00892.20 GAP89830.1 - 1.7e-23 83.3 32.7 8.3e-13 48.7 10.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF3021 PF11457.8 GAP89830.1 - 0.91 9.9 13.3 0.93 9.8 0.9 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF3021) DUF5336 PF17270.2 GAP89830.1 - 4.1 7.0 11.5 1.6 8.3 1.0 3.3 1 1 3 4 4 4 0 Family of unknown function (DUF5336) YwiC PF14256.6 GAP89830.1 - 6 7.2 11.0 0.23 11.8 1.9 2.8 2 1 1 3 3 3 0 YwiC-like protein Ribosomal_S17 PF00366.20 GAP89831.1 - 2.9e-16 59.3 1.2 4e-16 58.9 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 SGT1 PF07093.11 GAP89832.1 - 3.6e-90 303.1 6.4 1.4e-79 268.2 0.0 2.1 2 0 0 2 2 2 2 SGT1 protein SMC_N PF02463.19 GAP89833.1 - 1.2e-21 77.2 1.9 1.1e-20 74.0 1.9 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAP89833.1 - 3.6e-17 63.5 4.4 3.6e-17 63.5 4.4 5.3 3 1 1 4 4 3 1 AAA domain AAA_15 PF13175.6 GAP89833.1 - 1.3e-11 44.9 0.0 1.3e-11 44.9 0.0 3.4 1 1 2 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 GAP89833.1 - 4.7e-06 26.6 1.5 0.0017 18.2 0.1 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Laminin_II PF06009.12 GAP89833.1 - 1.5e-05 25.0 38.8 0.017 15.2 0.7 6.0 4 2 0 5 5 5 5 Laminin Domain II SbcCD_C PF13558.6 GAP89833.1 - 0.0018 18.4 0.0 0.011 15.9 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 GAP89833.1 - 0.0021 17.8 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 GAP89833.1 - 0.0022 18.3 0.0 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain IFT57 PF10498.9 GAP89833.1 - 0.0036 16.3 5.9 0.0036 16.3 5.9 5.6 3 2 2 6 6 6 3 Intra-flagellar transport protein 57 DUF745 PF05335.13 GAP89833.1 - 0.0074 16.0 6.7 0.0074 16.0 6.7 6.4 3 2 2 6 6 5 1 Protein of unknown function (DUF745) DASH_Hsk3 PF08227.11 GAP89833.1 - 0.013 15.8 5.5 0.12 12.7 1.4 3.3 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like ABC_tran PF00005.27 GAP89833.1 - 0.1 13.1 0.2 0.1 13.1 0.2 5.2 4 2 0 4 4 3 0 ABC transporter Myb_DNA-bind_3 PF12776.7 GAP89833.1 - 0.25 12.4 7.4 3.1 8.8 0.2 4.2 4 0 0 4 4 3 0 Myb/SANT-like DNA-binding domain DUF802 PF05650.11 GAP89833.1 - 3.1 8.3 8.1 1.5 9.3 3.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF802) COQ9 PF08511.11 GAP89834.1 - 9.3e-29 99.0 0.0 3.4e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 COQ9 RRM_1 PF00076.22 GAP89835.1 - 1.1e-48 162.8 0.0 8.9e-15 54.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 GAP89835.1 - 0.0005 20.1 0.0 3.1 7.9 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.10 GAP89835.1 - 0.0039 16.8 0.0 0.077 12.6 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain Limkain-b1 PF11608.8 GAP89835.1 - 0.0046 17.0 0.2 9.5 6.4 0.0 3.9 4 1 0 4 4 4 1 Limkain b1 RRM_occluded PF16842.5 GAP89835.1 - 0.088 12.7 0.0 3.9 7.4 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_5 PF13893.6 GAP89835.1 - 0.12 11.9 0.0 11 5.6 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3343 PF11823.8 GAP89835.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) RRM_Rrp7 PF17799.1 GAP89835.1 - 0.16 11.7 0.0 30 4.4 0.0 2.7 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain SRP14 PF02290.15 GAP89836.1 - 1.5e-28 99.0 0.0 2.4e-28 98.4 0.0 1.3 2 0 0 2 2 2 1 Signal recognition particle 14kD protein HalOD1 PF18545.1 GAP89836.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 2 0 0 2 2 2 0 Halobacterial output domain 1 2-Hacid_dh_C PF02826.19 GAP89837.1 - 5.9e-31 107.2 0.0 8.4e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP89837.1 - 0.037 13.7 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MIF4G PF02854.19 GAP89838.1 - 3.7e-19 69.2 0.1 6.1e-19 68.5 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 GAP89838.1 - 3.6e-06 26.9 0.0 5.1e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 MA3 domain ZapB PF06005.12 GAP89838.1 - 0.021 15.3 0.8 0.58 10.6 0.4 3.1 2 0 0 2 2 2 0 Cell division protein ZapB Spem1 PF15670.5 GAP89838.1 - 0.58 9.7 4.9 1.8 8.1 4.7 1.9 2 0 0 2 2 2 0 Spermatid maturation protein 1 Pyr_redox_2 PF07992.14 GAP89839.1 - 2.6e-67 227.1 6.2 3.5e-67 226.7 6.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 GAP89839.1 - 1.8e-41 140.8 0.0 4.8e-41 139.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 GAP89839.1 - 4.6e-21 75.2 11.8 1.2e-19 70.7 0.7 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP89839.1 - 2.1e-10 40.6 3.7 6.2e-06 26.4 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAP89839.1 - 7.2e-10 38.5 10.5 9.5e-08 31.5 6.0 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAP89839.1 - 4.2e-09 36.3 8.7 8.7e-09 35.2 0.8 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP89839.1 - 9.1e-08 31.6 9.3 4.7e-07 29.2 4.1 2.9 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAP89839.1 - 2.8e-07 30.1 1.8 0.013 14.8 0.1 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAP89839.1 - 1.4e-06 27.8 3.1 3.2e-05 23.3 0.2 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 GAP89839.1 - 1.5e-06 28.1 11.8 0.0052 16.4 0.6 4.2 4 0 0 4 4 4 3 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 GAP89839.1 - 2e-06 27.3 5.6 0.00033 20.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 GAP89839.1 - 3.6e-06 25.9 14.3 0.00027 19.8 2.8 4.1 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox_3 PF13738.6 GAP89839.1 - 4.9e-06 26.0 6.5 0.00056 19.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP89839.1 - 0.00012 21.3 0.5 0.38 9.9 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 GAP89839.1 - 0.00015 21.0 1.6 0.0033 16.5 0.0 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein HTH_23 PF13384.6 GAP89839.1 - 0.1 12.4 0.2 12 5.8 0.1 2.5 2 0 0 2 2 2 0 Homeodomain-like domain NAD_binding_7 PF13241.6 GAP89839.1 - 0.12 12.8 3.0 7.4 7.1 0.5 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 GAP89839.1 - 5.8 6.8 6.5 1.6 8.6 0.2 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 GAP89841.1 - 2.4e-30 105.6 0.0 4.1e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAP89841.1 - 7.7e-27 93.9 0.0 1.4e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAP89841.1 - 6.4e-08 32.4 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAP89841.1 - 8.3e-07 29.3 0.8 1.8e-06 28.2 0.2 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Glu_dehyd_C PF16912.5 GAP89841.1 - 0.0075 15.8 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus KR PF08659.10 GAP89841.1 - 0.014 15.3 0.0 0.069 13.1 0.0 2.1 2 0 0 2 2 2 0 KR domain AMP-binding_C PF13193.6 GAP89841.1 - 0.02 15.8 0.0 0.27 12.2 0.0 2.6 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain PHTB1_C PF14728.6 GAP89841.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus Polysacc_synt_2 PF02719.15 GAP89841.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 GAP89841.1 - 0.1 13.0 0.0 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Cys_Met_Meta_PP PF01053.20 GAP89842.1 - 1.2e-22 80.0 0.0 3.6e-18 65.3 0.0 2.3 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Spt20 PF12090.8 GAP89842.1 - 0.084 12.5 9.8 0.12 11.9 9.8 1.1 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 GAP89842.1 - 0.54 8.9 2.1 0.67 8.6 2.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ORC6 PF05460.13 GAP89842.1 - 1.2 8.3 6.5 1.8 7.7 6.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) THUMP PF02926.17 GAP89843.1 - 5.5e-12 46.0 0.4 1.1e-11 45.1 0.1 1.6 2 0 0 2 2 2 1 THUMP domain Pinin_SDK_N PF04697.13 GAP89843.1 - 0.24 12.0 9.8 5.6 7.6 0.5 3.2 1 1 1 2 2 2 0 pinin/SDK conserved region LCAT PF02450.15 GAP89844.1 - 2.5e-106 356.2 0.0 3.1e-106 355.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Acetyltransf_1 PF00583.25 GAP89845.1 - 1e-19 70.8 0.0 1.3e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAP89845.1 - 3.9e-10 39.6 0.0 6.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAP89845.1 - 3.9e-10 39.8 0.0 5.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP89845.1 - 2.2e-09 37.6 0.0 3.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAP89845.1 - 7.6e-07 29.9 0.0 9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAP89845.1 - 2.5e-06 27.2 0.0 3.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP89845.1 - 0.00012 22.1 0.1 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAP89845.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF1917 PF08939.10 GAP89846.1 - 4.5e-77 259.5 0.0 5.5e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) WD40 PF00400.32 GAP89847.1 - 0.002 18.9 3.3 0.058 14.3 0.0 4.3 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP89847.1 - 0.068 13.5 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Xpo1 PF08389.12 GAP89848.1 - 3.4e-07 30.4 0.1 7.3e-06 26.1 0.1 3.1 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 GAP89848.1 - 5.5e-07 29.4 0.3 2.1e-05 24.3 0.0 3.6 3 1 1 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.22 GAP89848.1 - 0.0049 17.0 0.3 0.52 10.7 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat IFRD PF05004.13 GAP89848.1 - 0.064 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) DUF2013 PF09431.10 GAP89849.1 - 2.6e-50 170.2 3.2 4.1e-50 169.5 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) PH PF00169.29 GAP89850.1 - 0.0004 20.9 0.0 0.00098 19.6 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF5344 PF17279.2 GAP89850.1 - 0.027 15.1 0.6 0.36 11.5 0.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Prominin PF05478.11 GAP89850.1 - 0.056 11.4 0.2 0.087 10.8 0.2 1.2 1 0 0 1 1 1 0 Prominin Gar1 PF04410.14 GAP89851.1 - 4e-21 75.4 0.0 6e-15 55.3 0.0 2.0 1 1 1 2 2 2 2 Gar1/Naf1 RNA binding region TRI5 PF06330.11 GAP89852.1 - 7.4e-19 67.8 0.1 9.7e-19 67.4 0.1 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF411 PF04214.13 GAP89855.1 - 0.064 13.2 0.0 6.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF TPP_enzyme_M PF00205.22 GAP89856.1 - 2.5e-22 79.1 0.0 4.3e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 GAP89856.1 - 1.4e-12 47.7 0.0 2.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 GAP89856.1 - 4.4e-05 23.2 0.9 0.064 12.9 0.0 2.7 1 1 1 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain E1-N PF14463.6 GAP89856.1 - 0.034 14.0 3.7 0.028 14.3 1.3 2.1 2 0 0 2 2 2 0 E1 N-terminal domain BPL_LplA_LipB_2 PF16917.5 GAP89856.1 - 0.034 13.7 0.1 0.081 12.5 0.1 1.6 2 0 0 2 2 2 0 Biotin/lipoate A/B protein ligase family TPP_enzyme_N PF02776.18 GAP89857.1 - 3.9e-08 33.1 0.0 4.2e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Evr1_Alr PF04777.13 GAP89858.1 - 6.2e-31 106.8 1.0 6.2e-31 106.8 1.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family HEM4 PF02602.15 GAP89859.1 - 3.6e-36 124.7 0.0 5e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TLD PF07534.16 GAP89860.1 - 2.4e-20 73.1 0.0 3.9e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 TLD AP3B1_C PF14796.6 GAP89860.1 - 0.15 12.3 0.5 0.27 11.5 0.5 1.4 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Pkinase PF00069.25 GAP89861.1 - 3.7e-68 229.8 0.0 4.9e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89861.1 - 4.8e-32 111.3 0.0 6.3e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP89861.1 - 0.00034 20.0 0.3 0.00058 19.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAP89861.1 - 0.0013 17.7 0.2 0.0023 16.9 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAP89861.1 - 0.0088 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAP89861.1 - 0.028 14.3 0.2 0.062 13.2 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 GAP89861.1 - 0.07 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 S_100 PF01023.19 GAP89861.1 - 0.13 12.0 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Sec23_trunk PF04811.15 GAP89862.1 - 6.5e-73 245.3 0.0 2.9e-72 243.2 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAP89862.1 - 4e-22 78.0 0.0 1.9e-21 75.8 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAP89862.1 - 1.9e-18 66.9 0.0 3.8e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAP89862.1 - 4.5e-17 61.8 4.9 8.1e-17 61.0 4.9 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAP89862.1 - 6.4e-10 38.8 0.0 1.4e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 GAP89862.1 - 0.043 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 GAP89862.1 - 0.061 14.0 0.0 1.4 9.6 0.0 2.8 3 0 0 3 3 3 0 von Willebrand factor type A domain Orthopox_A36R PF05950.11 GAP89863.1 - 0.008 16.4 0.0 0.0092 16.2 0.0 1.2 1 0 0 1 1 1 1 Orthopoxvirus A36R protein LapA_dom PF06305.11 GAP89863.1 - 0.041 13.7 0.7 0.058 13.2 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Fungal_trans_2 PF11951.8 GAP89864.1 - 7e-12 44.9 1.1 9.6e-12 44.4 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.21 GAP89867.1 - 1.2e-57 195.1 0.0 1.8e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ECM11 PF15463.6 GAP89867.1 - 0.045 14.3 1.1 0.088 13.4 0.1 1.9 2 0 0 2 2 2 0 Extracellular mutant protein 11 YjbR PF04237.13 GAP89867.1 - 0.13 12.9 0.4 0.6 10.7 0.1 2.3 2 0 0 2 2 2 0 YjbR DAHP_synth_2 PF01474.16 GAP89867.1 - 0.21 10.1 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Class-II DAHP synthetase family CDP-OH_P_transf PF01066.21 GAP89868.1 - 5.7e-12 46.2 0.1 1.3e-11 45.0 0.1 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.8 GAP89869.1 - 2.4e-121 405.3 0.0 3.2e-121 404.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 GAP89869.1 - 1.9e-06 27.8 0.1 0.0077 16.2 0.1 2.2 1 1 1 2 2 2 2 Jacalin-like lectin domain Whi5 PF08528.11 GAP89870.1 - 3.6e-08 32.8 0.0 6.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Whi5 like BPS1 PF05633.11 GAP89870.1 - 0.034 13.2 0.5 0.047 12.7 0.5 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related Laminin_G_3 PF13385.6 GAP89871.1 - 5.9e-05 23.3 0.1 8.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_16 PF00722.21 GAP89871.1 - 0.00013 21.5 0.0 0.00017 21.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Ank_2 PF12796.7 GAP89872.1 - 6.7e-97 318.2 0.4 1.7e-18 66.9 0.0 6.8 2 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP89872.1 - 4.5e-47 157.8 0.0 2.9e-08 34.1 0.0 9.3 5 3 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP89872.1 - 1.5e-36 120.2 0.0 0.035 14.6 0.0 13.3 13 0 0 13 13 13 9 Ankyrin repeat Ank PF00023.30 GAP89872.1 - 8e-31 105.1 2.7 0.0033 17.8 0.0 12.3 13 1 1 14 14 14 6 Ankyrin repeat Ank_5 PF13857.6 GAP89872.1 - 4e-27 93.9 0.0 2e-05 24.8 0.0 10.1 4 2 7 11 11 11 9 Ankyrin repeats (many copies) HET PF06985.11 GAP89872.1 - 2.8e-07 31.0 2.1 4.6e-06 27.0 0.6 2.3 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) VWA_3_C PF18571.1 GAP89872.1 - 0.35 10.8 14.0 22 5.0 0.1 7.2 8 0 0 8 8 8 0 von Willebrand factor type A C-terminal domain DUF4328 PF14219.6 GAP89874.1 - 0.093 12.3 1.2 0.16 11.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Peptidase_C14 PF00656.22 GAP89876.1 - 2.9e-63 214.1 0.0 3.9e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Cnn_1N PF07989.11 GAP89877.1 - 2.2e-26 91.8 4.4 2.2e-26 91.8 4.4 15.8 6 2 9 16 16 15 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 GAP89877.1 - 3.2e-06 27.6 13.5 8e-05 23.1 0.9 5.5 6 2 1 7 7 3 2 Pericentrin-AKAP-450 domain of centrosomal targeting protein Filament PF00038.21 GAP89877.1 - 7.2e-06 25.8 42.9 7.2e-06 25.8 42.9 8.9 2 1 7 9 9 9 3 Intermediate filament protein HMMR_N PF15905.5 GAP89877.1 - 2.5e-05 23.9 54.6 7.2e-05 22.4 25.6 8.6 3 2 4 8 8 8 4 Hyaluronan mediated motility receptor N-terminal HsbA PF12296.8 GAP89877.1 - 4.2e-05 24.0 23.5 0.00012 22.5 0.3 7.2 4 3 4 8 8 8 1 Hydrophobic surface binding protein A Spc7 PF08317.11 GAP89877.1 - 0.0002 20.4 191.3 0.00093 18.2 23.7 9.2 1 1 9 10 10 10 7 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 GAP89877.1 - 0.00029 21.0 29.7 0.00029 21.0 29.7 10.9 1 1 9 10 10 8 3 Tropomyosin like TPR_MLP1_2 PF07926.12 GAP89877.1 - 0.0065 16.5 16.4 0.0065 16.5 16.4 12.5 2 1 8 11 11 10 3 TPR/MLP1/MLP2-like protein Ntox28 PF15605.6 GAP89877.1 - 0.0074 16.5 5.7 0.0074 16.5 5.7 9.2 2 2 9 12 12 12 1 Bacterial toxin 28 ABC_tran_CTD PF16326.5 GAP89877.1 - 0.0083 16.4 2.3 0.0083 16.4 2.3 15.5 6 4 8 15 15 12 4 ABC transporter C-terminal domain Fez1 PF06818.15 GAP89877.1 - 0.011 16.3 186.0 0.45 10.9 22.5 8.9 1 1 8 9 9 9 0 Fez1 Golgin_A5 PF09787.9 GAP89877.1 - 0.1 12.0 188.0 0.27 10.7 29.4 9.2 1 1 9 10 10 10 0 Golgin subfamily A member 5 Lebercilin PF15619.6 GAP89877.1 - 0.28 10.8 210.4 0.011 15.4 13.8 11.4 2 1 9 11 11 11 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 GAP89877.1 - 0.65 10.0 104.4 0.078 13.0 5.3 11.7 3 1 12 15 15 15 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 GAP89877.1 - 2 6.9 138.7 0.0035 16.1 24.2 6.3 1 1 4 5 5 5 0 AAA domain GAS PF13851.6 GAP89877.1 - 2.1 7.6 186.0 0.027 13.8 21.5 11.1 1 1 8 10 10 10 0 Growth-arrest specific micro-tubule binding DpnI_C PF17726.1 GAP89877.1 - 4.3 7.5 7.3 8.1 6.7 0.1 3.8 3 0 0 3 3 3 0 Dam-replacing HTH domain MscS_porin PF12795.7 GAP89877.1 - 8.1 5.9 211.4 0.03 13.9 16.2 8.6 1 1 4 6 6 5 0 Mechanosensitive ion channel porin domain Transglut_core2 PF13369.6 GAP89878.1 - 3.7e-15 55.8 0.0 6.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 GAP89878.1 - 2e-14 53.9 0.0 4e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.7 GAP89878.1 - 2.4e-12 46.6 0.2 6.5e-12 45.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP89878.1 - 6e-07 29.2 0.2 3.3e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.11 GAP89878.1 - 0.041 14.4 0.0 0.073 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_5 PF18511.1 GAP89878.1 - 0.094 12.3 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 F-box Nrap_D4 PF17405.2 GAP89879.1 - 8.7e-59 198.4 0.1 1.5e-58 197.7 0.1 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 GAP89879.1 - 1.2e-50 171.4 0.3 2.7e-50 170.3 0.3 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 GAP89879.1 - 8.3e-47 158.8 0.0 1.8e-44 151.2 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 GAP89879.1 - 2.8e-42 144.3 0.1 6.1e-42 143.2 0.1 1.6 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 GAP89879.1 - 5.7e-35 120.8 0.0 1.3e-34 119.6 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 GAP89879.1 - 3.4e-32 111.5 0.0 1.5e-31 109.4 0.0 2.1 2 0 0 2 2 2 1 Nrap protein domain 6 DUF2805 PF10985.8 GAP89879.1 - 0.17 12.3 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) CoA_trans PF01144.23 GAP89880.1 - 2.9e-98 327.6 0.7 2.5e-59 200.3 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase adh_short PF00106.25 GAP89882.1 - 3.1e-16 59.4 0.0 4.4e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP89882.1 - 1.5e-14 54.1 0.0 2.2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP89882.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 GAP89882.1 - 0.014 14.9 0.0 0.018 14.5 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CAP_N PF01213.19 GAP89882.1 - 0.017 14.6 8.0 0.064 12.7 0.5 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ADH_zinc_N PF00107.26 GAP89882.1 - 0.035 14.1 0.2 0.098 12.6 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase VIR_N PF15912.5 GAP89882.1 - 0.46 10.0 3.6 1.7 8.2 0.2 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal Dscam_C PF12355.8 GAP89882.1 - 1.7 9.6 14.5 2.8 8.9 3.1 2.7 2 1 1 3 3 3 0 Down syndrome cell adhesion molecule C terminal NACHT PF05729.12 GAP89883.1 - 2.8e-09 37.1 0.9 8.3e-08 32.3 0.1 3.2 3 0 0 3 3 2 1 NACHT domain SesA PF17107.5 GAP89883.1 - 1.1e-06 28.8 1.1 1.1e-06 28.8 1.1 2.5 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 GAP89883.1 - 1.4e-05 25.3 1.1 0.00032 21.0 0.0 3.1 3 2 0 3 3 3 1 AAA domain AAA_16 PF13191.6 GAP89883.1 - 3.8e-05 24.1 4.0 9.8e-05 22.8 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_18 PF13238.6 GAP89883.1 - 0.00017 22.2 0.0 0.00066 20.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 GAP89883.1 - 0.0023 18.5 1.6 0.0088 16.6 0.0 2.6 2 2 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 GAP89883.1 - 0.0046 16.7 0.4 0.01 15.5 0.4 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ank_2 PF12796.7 GAP89883.1 - 0.0048 17.5 0.1 7.9 7.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) AAA_14 PF13173.6 GAP89883.1 - 0.0075 16.3 0.0 2.5 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 GAP89883.1 - 0.012 15.6 0.0 0.043 13.7 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 GAP89883.1 - 0.019 14.9 0.2 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 GAP89883.1 - 0.023 15.1 0.4 0.12 12.7 0.1 2.5 3 0 0 3 3 2 0 RNA helicase RsgA_GTPase PF03193.16 GAP89883.1 - 0.032 14.1 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 GAP89883.1 - 0.034 13.9 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 GAP89883.1 - 0.04 12.9 0.3 1.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 GAP89883.1 - 0.073 13.3 0.1 0.26 11.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAP89883.1 - 0.073 12.2 0.0 0.26 10.5 0.0 1.9 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 GAP89883.1 - 0.081 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 GAP89883.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ST7 PF04184.12 GAP89883.1 - 0.32 9.4 1.8 0.5 8.8 1.8 1.2 1 0 0 1 1 1 0 ST7 protein AAA_23 PF13476.6 GAP89883.1 - 0.76 10.2 3.4 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 GAP89884.1 - 8.3e-21 74.3 58.9 3.1e-19 69.1 48.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.11 GAP89884.1 - 0.65 9.9 36.2 2.3 8.0 12.7 3.9 1 1 2 3 3 3 0 7TM diverse intracellular signalling DUF1129 PF06570.11 GAP89884.1 - 0.81 9.1 5.6 0.58 9.6 3.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Ank_4 PF13637.6 GAP89885.1 - 0.00068 20.2 0.0 0.002 18.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) CoaE PF01121.20 GAP89885.1 - 0.04 13.6 0.1 0.073 12.7 0.1 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase Ank_2 PF12796.7 GAP89886.1 - 4.3e-73 241.9 5.7 4.6e-09 36.7 0.0 12.6 6 2 6 13 13 13 10 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP89886.1 - 4.3e-53 171.1 20.1 0.00024 21.3 0.0 19.6 20 0 0 20 20 20 10 Ankyrin repeat Ank_4 PF13637.6 GAP89886.1 - 1.1e-47 159.8 13.4 1e-08 35.5 0.0 15.1 14 2 3 17 17 17 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP89886.1 - 4.6e-43 144.7 4.3 2.6e-07 30.8 0.0 13.1 8 3 4 12 12 12 8 Ankyrin repeats (many copies) Ank PF00023.30 GAP89886.1 - 2.4e-42 141.6 17.0 5.4e-05 23.5 0.0 16.5 15 1 1 16 16 16 7 Ankyrin repeat NACHT PF05729.12 GAP89886.1 - 3.7e-08 33.5 0.1 1.3e-07 31.7 0.1 2.0 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 GAP89886.1 - 2.3e-06 27.1 1.0 6.4e-06 25.7 1.0 1.8 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 GAP89886.1 - 0.0011 19.3 0.0 0.0037 17.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP89886.1 - 0.0032 17.9 0.3 0.014 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 GAP89886.1 - 0.021 15.2 0.0 0.059 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DDE_1 PF03184.19 GAP89887.1 - 3.5e-23 82.2 0.1 1.1e-22 80.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 GAP89887.1 - 0.00056 19.9 0.1 0.0034 17.4 0.0 2.4 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 GAP89887.1 - 0.00097 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HET PF06985.11 GAP89888.1 - 5.3e-28 98.2 0.0 9e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ketoacyl-synt PF00109.26 GAP89889.1 - 1.2e-75 254.4 0.0 2.7e-75 253.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 GAP89889.1 - 3.8e-35 121.7 3.1 1.1e-34 120.2 0.8 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ketoacyl-synt_C PF02801.22 GAP89889.1 - 2.7e-34 117.7 0.4 7.9e-34 116.2 0.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 GAP89889.1 - 4.4e-30 105.3 0.0 5.8e-28 98.3 0.0 3.1 2 1 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 GAP89889.1 - 8.2e-26 90.9 0.1 1.4e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 GAP89889.1 - 9.7e-13 48.8 0.0 3e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 GAP89889.1 - 1.9e-07 31.3 1.3 4.1e-07 30.3 1.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 GAP89889.1 - 2.1e-05 25.2 15.1 7.4e-05 23.4 10.1 3.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 GAP89889.1 - 6.3e-05 22.5 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_1 PF00561.20 GAP89889.1 - 0.012 15.2 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAP89891.1 - 3.7e-22 79.2 0.2 5.3e-22 78.7 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP89891.1 - 5.1e-16 58.5 0.0 6e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 GAP89891.1 - 0.00057 20.6 0.5 0.00079 20.1 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 GAP89891.1 - 0.0015 18.4 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 GAP89891.1 - 0.036 13.8 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 GAP89891.1 - 0.071 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Methyltransf_25 PF13649.6 GAP89892.1 - 2.1e-10 41.2 0.0 3.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP89892.1 - 4.2e-08 33.7 0.0 7.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP89892.1 - 1.2e-07 32.4 0.0 1.9e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP89892.1 - 2.3e-07 30.7 0.0 3.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP89892.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAP89892.1 - 0.024 14.5 0.0 0.06 13.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PPR_long PF17177.4 GAP89892.1 - 0.18 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Gpr1_Fun34_YaaH PF01184.19 GAP89894.1 - 2.7e-31 108.8 25.2 3.3e-31 108.5 25.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family zf-CCCH PF00642.24 GAP89895.1 - 3.4e-11 42.7 8.4 4.9e-06 26.3 1.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAP89895.1 - 5.5e-11 42.1 16.5 6.2e-06 26.1 3.4 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 GAP89895.1 - 1.6e-09 37.4 11.6 4e-05 23.3 3.9 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 GAP89895.1 - 1.8e-07 31.8 6.4 0.002 18.8 0.7 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 GAP89895.1 - 3.6e-07 30.4 0.3 7.9e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 GAP89895.1 - 0.016 15.7 16.6 0.2 12.2 2.8 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger NACHT PF05729.12 GAP89896.1 - 7.3e-08 32.5 0.3 1.9e-07 31.1 0.3 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP89896.1 - 1.9e-06 28.4 1.1 8.7e-06 26.2 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain KinB_sensor PF16767.5 GAP89896.1 - 0.00043 20.7 5.6 0.0015 18.9 0.1 3.4 3 0 0 3 3 3 1 Sensor domain of alginate biosynthesis sensor protein KinB ATPase_2 PF01637.18 GAP89896.1 - 0.0038 17.2 0.2 0.012 15.5 0.2 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 GAP89896.1 - 0.004 16.7 0.1 0.011 15.3 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 GAP89896.1 - 0.0065 16.8 1.1 0.66 10.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 GAP89896.1 - 0.011 14.9 1.0 0.052 12.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2732 PF10809.8 GAP89896.1 - 0.35 10.8 3.8 6.3 6.7 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) DUF2497 PF10691.9 GAP89896.1 - 2.2 8.8 4.6 2.7 8.5 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2497) SNF2_N PF00176.23 GAP89897.1 - 6.9e-58 196.0 0.0 1e-57 195.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 GAP89897.1 - 2.3e-07 31.0 0.0 4.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAP89897.1 - 4e-05 23.9 0.0 0.00015 22.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 GAP89897.1 - 0.054 13.2 0.0 6.4 6.4 0.0 2.4 2 0 0 2 2 2 0 SWI2/SNF2 ATPase zf-C3HC4 PF00097.25 GAP89897.1 - 2.7 7.9 5.3 7.9 6.4 5.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP89897.1 - 2.7 8.0 5.3 6.7 6.8 5.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain MFS_1 PF07690.16 GAP89898.1 - 7.6e-14 51.4 68.0 2.3e-08 33.4 39.6 3.0 2 1 2 4 4 4 3 Major Facilitator Superfamily TRI12 PF06609.13 GAP89898.1 - 3.7e-08 32.2 17.6 3.7e-08 32.2 17.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DNA_pol_delta_4 PF04081.13 GAP89898.1 - 0.053 13.9 0.0 0.097 13.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase delta, subunit 4 DUF3341 PF11821.8 GAP89898.1 - 7.4 6.2 10.2 0.19 11.4 2.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3341) adh_short_C2 PF13561.6 GAP89899.1 - 5e-60 203.0 1.2 5.9e-60 202.7 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP89899.1 - 2.2e-47 161.0 0.8 3e-47 160.6 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP89899.1 - 2.1e-08 34.3 0.5 6.1e-08 32.8 0.5 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP89899.1 - 0.0019 17.7 0.2 0.0029 17.1 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 GAP89899.1 - 0.095 12.6 0.7 0.14 12.0 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RicinB_lectin_2 PF14200.6 GAP89900.1 - 0.029 15.1 0.4 0.73 10.6 0.2 2.6 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like SH2 PF00017.24 GAP89900.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 SH2 domain FSA_C PF10479.9 GAP89900.1 - 1.7 6.6 3.7 2.8 6.0 3.7 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus HET PF06985.11 GAP89901.1 - 1.7e-24 86.8 0.0 3.6e-24 85.8 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GspL_C PF12693.7 GAP89902.1 - 0.093 12.6 0.1 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 GspL periplasmic domain Baculo_PEP_C PF04513.12 GAP89903.1 - 0.38 10.8 3.1 7.5 6.6 0.6 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Streptin-Immun PF11083.8 GAP89903.1 - 6.8 7.2 12.4 1.8 9.0 5.4 3.0 3 1 0 3 3 3 0 Lantibiotic streptin immunity protein Pkinase_fungal PF17667.1 GAP89904.1 - 1.1e-110 370.3 0.0 1.4e-110 369.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 GAP89904.1 - 0.0004 19.8 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain STPPase_N PF16891.5 GAP89904.1 - 0.15 12.5 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain PI-PLC-X PF00388.19 GAP89907.1 - 1.2e-55 187.1 0.0 1.9e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAP89907.1 - 4.6e-41 139.8 0.3 7.9e-41 139.0 0.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain RabGAP-TBC PF00566.18 GAP89908.1 - 5.9e-48 163.4 0.0 1e-47 162.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 GAP89908.1 - 0.0002 21.0 0.2 0.04 13.9 0.2 3.2 2 0 0 2 2 2 1 EF-hand domain GRAM PF02893.20 GAP89908.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.6 GAP89908.1 - 0.024 15.1 0.1 0.024 15.1 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 GAP89908.1 - 0.025 14.1 0.6 0.2 11.3 0.5 2.7 3 0 0 3 3 3 0 EF hand EF-hand_5 PF13202.6 GAP89908.1 - 0.064 12.8 0.3 0.26 10.8 0.2 2.1 2 0 0 2 2 2 0 EF hand DUF4611 PF15387.6 GAP89908.1 - 0.38 11.0 16.1 25 5.2 0.6 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Pkinase PF00069.25 GAP89909.1 - 2.3e-65 220.6 0.0 3.2e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89909.1 - 1e-32 113.4 0.0 1.8e-32 112.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP89909.1 - 6.5e-05 22.4 0.0 8.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAP89909.1 - 0.0052 16.7 0.1 0.034 14.1 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 GAP89909.1 - 0.05 12.4 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 GAP89909.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 GAP89909.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_2 PF13639.6 GAP89911.1 - 2.1e-12 47.2 5.1 3.3e-12 46.5 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 GAP89911.1 - 5.7e-10 39.1 0.0 1.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 GAP89911.1 - 5e-09 36.3 2.0 9.1e-09 35.5 2.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAP89911.1 - 5.3e-09 35.8 4.0 8.4e-09 35.1 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP89911.1 - 1.3e-08 34.6 2.7 2.1e-08 33.9 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAP89911.1 - 1.4e-08 34.3 2.2 1.4e-08 34.3 2.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 GAP89911.1 - 1.2e-06 28.4 2.0 2e-06 27.7 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAP89911.1 - 2e-05 24.3 2.8 3.1e-05 23.7 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP89911.1 - 2.9e-05 24.0 2.1 0.00032 20.6 2.9 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 GAP89911.1 - 0.0016 18.5 1.0 0.003 17.6 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 GAP89911.1 - 0.014 15.2 2.9 0.028 14.3 2.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAP89911.1 - 0.041 14.0 3.4 0.14 12.4 3.5 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 GAP89911.1 - 0.068 12.8 3.1 0.13 11.9 3.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 GAP89911.1 - 0.16 12.2 2.1 0.41 10.9 2.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 GAP89911.1 - 0.19 12.0 3.0 0.33 11.3 3.0 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 GAP89911.1 - 0.24 11.5 2.2 0.5 10.5 2.2 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 GAP89911.1 - 0.35 10.7 2.6 0.76 9.6 2.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 GAP89911.1 - 0.79 9.7 2.4 1.4 8.8 2.4 1.5 1 0 0 1 1 1 0 PHD-finger EI24 PF07264.11 GAP89912.1 - 9.3e-14 52.1 5.6 1.7e-13 51.2 5.6 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ATP-sulfurylase PF01747.17 GAP89914.1 - 5.1e-87 290.8 0.0 7.2e-87 290.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 GAP89914.1 - 2.5e-58 196.4 0.0 3.8e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 GAP89914.1 - 4.6e-53 179.1 0.0 7.8e-53 178.4 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain C166 PF17615.2 GAP89916.1 - 4e-62 209.0 10.4 4.8e-62 208.8 10.4 1.1 1 0 0 1 1 1 1 Family of unknown function HsbA PF12296.8 GAP89916.1 - 0.00018 21.9 3.0 0.0011 19.4 2.8 2.4 1 1 0 1 1 1 1 Hydrophobic surface binding protein A ARPC4 PF05856.12 GAP89917.1 - 3.6e-80 267.4 4.6 4e-80 267.3 4.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 GAP89917.1 - 0.04 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Sm_like domain UCH PF00443.29 GAP89918.1 - 6.5e-50 170.0 0.0 8.6e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAP89918.1 - 1.9e-12 47.4 7.5 7.9e-08 32.2 3.3 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 GAP89918.1 - 1.4e-09 37.5 0.0 3.7e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 GAP89918.1 - 0.053 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain RskA PF10099.9 GAP89919.1 - 0.044 14.1 0.7 0.051 13.9 0.7 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FTR1 PF03239.14 GAP89919.1 - 0.1 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family Methyltransf_31 PF13847.6 GAP89920.1 - 8.1e-14 51.7 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP89920.1 - 1e-13 51.4 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP89920.1 - 7.8e-13 48.9 0.0 1.4e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP89920.1 - 1e-12 48.6 0.1 4.1e-12 46.6 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP89920.1 - 1.9e-10 41.4 0.0 3.9e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP89920.1 - 2.6e-06 26.9 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 GAP89920.1 - 0.00068 19.6 0.0 0.0016 18.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAP89920.1 - 0.16 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.19 GAP89920.1 - 0.22 11.3 0.0 0.57 9.9 0.0 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Zn_clus PF00172.18 GAP89921.1 - 1.1e-08 35.0 7.4 1.6e-08 34.5 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GAT PF03127.14 GAP89923.1 - 5.2e-19 68.3 0.5 1.8e-18 66.6 0.1 2.1 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 GAP89923.1 - 2.5e-05 24.2 0.0 0.00012 21.9 0.0 2.0 2 0 0 2 2 2 1 VHS domain Cas_APE2256 PF09651.10 GAP89923.1 - 0.0052 16.7 0.2 2.1 8.2 0.1 3.1 2 1 1 3 3 3 1 CRISPR-associated protein (Cas_APE2256) SET PF00856.28 GAP89924.1 - 1.4e-16 61.3 3.2 2.2e-16 60.7 0.8 2.6 2 1 0 2 2 2 1 SET domain AWS PF17907.1 GAP89924.1 - 1.6e-07 31.3 6.4 3.7e-07 30.1 6.4 1.7 1 0 0 1 1 1 1 AWS domain dCMP_cyt_deam_1 PF00383.23 GAP89925.1 - 7.1e-20 70.8 0.0 1.2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAP89925.1 - 6.8e-15 55.0 0.0 1.4e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 GAP89925.1 - 0.00064 19.8 0.3 0.013 15.6 0.3 2.5 1 1 0 1 1 1 1 Bd3614-like deaminase Pec_lyase_C PF00544.19 GAP89926.1 - 2.2e-12 47.0 9.4 3.1e-11 43.3 9.4 2.1 1 1 0 1 1 1 1 Pectate lyase Zn_clus PF00172.18 GAP89927.1 - 0.042 14.0 8.1 0.092 12.9 8.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2439 PF10382.9 GAP89929.1 - 6.4e-26 90.5 0.0 1.2e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SH3_1 PF00018.28 GAP89930.1 - 7.5e-14 51.1 0.2 1.3e-13 50.3 0.2 1.4 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 GAP89930.1 - 2.5e-11 43.7 0.6 2.2e-10 40.6 0.4 2.0 2 0 0 2 2 2 1 BAR domain SH3_9 PF14604.6 GAP89930.1 - 1.8e-10 40.5 0.0 3.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAP89930.1 - 7.6e-09 35.1 0.1 1.8e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Caskin-Pro-rich PF16907.5 GAP89930.1 - 0.00018 22.0 3.5 0.00018 22.0 3.5 3.0 4 0 0 4 4 4 1 Proline rich region of Caskin proteins Pil1 PF13805.6 GAP89930.1 - 0.0058 16.1 1.0 0.0097 15.4 1.0 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 Seryl_tRNA_N PF02403.22 GAP89930.1 - 0.065 13.5 0.7 0.15 12.3 0.7 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cep57_CLD PF14073.6 GAP89930.1 - 0.29 11.1 4.4 0.51 10.3 4.4 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 MARVEL PF01284.23 GAP89932.1 - 7.3e-05 22.8 16.1 0.0016 18.5 10.2 2.3 2 1 0 2 2 2 2 Membrane-associating domain VIT1 PF01988.19 GAP89932.1 - 0.0017 18.2 3.7 0.0017 18.2 3.7 1.3 1 1 0 1 1 1 1 VIT family DUF2070 PF09843.9 GAP89932.1 - 0.77 8.0 4.8 1 7.5 4.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Bot1p PF12298.8 GAP89934.1 - 1.2e-45 155.7 1.2 1.6e-45 155.4 0.2 1.7 2 1 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Sortilin-Vps10 PF15902.5 GAP89934.1 - 0.21 10.3 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, Response_reg PF00072.24 GAP89935.1 - 1.5e-20 73.4 0.0 7.4e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain PX PF00787.24 GAP89937.1 - 1.5e-25 89.4 0.0 2e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.27 GAP89938.1 - 1.8e-69 229.7 0.2 6.9e-23 80.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyoxalase PF00903.25 GAP89939.1 - 2e-12 47.4 0.0 2.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GAP89939.1 - 1.5e-06 29.0 0.2 1.7e-06 28.7 0.2 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 GAP89939.1 - 0.00022 21.4 0.1 0.001 19.3 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 GAP89939.1 - 0.0084 16.2 0.0 1.3 9.1 0.0 2.1 1 1 1 2 2 2 2 Glyoxalase-like domain Zn_clus PF00172.18 GAP89940.1 - 0.00026 21.0 12.2 0.00042 20.4 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MreB_Mbl PF06723.13 GAP89941.1 - 0.021 13.7 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein Pan3_PK PF18101.1 GAP89942.1 - 5.3e-58 194.9 0.0 8.7e-58 194.2 0.0 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 GAP89942.1 - 0.00019 20.9 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SUIM_assoc PF16619.5 GAP89942.1 - 2.1 8.5 12.0 8 6.6 12.0 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GAP89942.1 - 3.3 7.3 17.5 3.5 7.2 13.2 2.3 2 0 0 2 2 2 0 Spt20 family UBA_4 PF14555.6 GAP89943.1 - 5.7e-09 35.6 0.3 1.8e-08 34.0 0.3 1.9 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 GAP89943.1 - 1.9e-08 34.4 0.0 3.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain BRD4_CDT PF17105.5 GAP89943.1 - 0.48 10.1 3.5 1.5 8.5 3.5 1.8 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Peptidase_S49_N PF08496.10 GAP89943.1 - 2.1 8.4 4.4 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal K_channel_TID PF07941.11 GAP89943.1 - 3.8 8.0 8.8 11 6.6 8.8 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF1682 PF07946.14 GAP89943.1 - 4.4 6.4 8.2 10 5.2 6.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Macoilin PF09726.9 GAP89943.1 - 9.5 4.6 9.3 14 4.1 9.3 1.1 1 0 0 1 1 1 0 Macoilin family PRP21_like_P PF12230.8 GAP89944.1 - 1e-55 188.9 15.4 2.2e-54 184.6 14.6 2.7 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 GAP89944.1 - 6.7e-37 125.3 1.7 1.1e-18 67.0 0.1 2.5 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 GAP89944.1 - 0.026 14.1 0.3 0.066 12.8 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Toprim_Crpt PF13342.6 GAP89944.1 - 0.17 11.9 2.5 8.4 6.4 0.1 2.9 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase Guanylate_cyc_2 PF09778.9 GAP89945.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Guanylylate cyclase PMT PF02366.18 GAP89946.1 - 1.4e-79 267.1 16.9 3e-79 266.1 16.9 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 GAP89946.1 - 1e-67 227.6 11.6 1e-67 227.6 11.6 2.3 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 GAP89946.1 - 3.3e-45 154.2 0.2 5.9e-45 153.4 0.2 1.4 1 0 0 1 1 1 1 MIR domain Pkinase PF00069.25 GAP89948.1 - 1.7e-21 76.8 0.0 7.4e-21 74.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89948.1 - 5.1e-11 42.3 0.0 2.8e-10 39.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase GFA PF04828.14 GAP89949.1 - 3.4e-16 59.3 17.5 3.6e-08 33.6 1.4 3.9 5 0 0 5 5 5 3 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_60s PF00428.19 GAP89949.1 - 0.025 15.1 2.6 0.044 14.4 2.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein NOB1_Zn_bind PF08772.11 GAP89949.1 - 3.2 8.0 8.4 21 5.3 0.0 2.8 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Pkinase PF00069.25 GAP89950.1 - 2.7e-16 59.7 0.0 1.1e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89950.1 - 1.3e-10 41.0 0.0 0.00033 20.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TMEM154 PF15102.6 GAP89953.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Abhydrolase_9_N PF15420.6 GAP89953.1 - 0.062 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF347 PF03988.12 GAP89953.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) adh_short PF00106.25 GAP89954.1 - 2.9e-19 69.3 0.1 4.2e-19 68.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP89954.1 - 1.6e-09 37.7 0.1 2.6e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP89954.1 - 2.4e-07 30.8 0.2 4e-07 30.1 0.2 1.3 1 0 0 1 1 1 1 KR domain CRISPR_Cse2 PF09485.10 GAP89954.1 - 0.052 14.1 0.1 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) HET PF06985.11 GAP89955.1 - 2.4e-12 47.4 5.0 4.7e-10 40.0 0.4 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ribosomal_L44 PF00935.19 GAP89957.1 - 1.4e-35 121.6 12.1 2e-35 121.1 12.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Pkinase PF00069.25 GAP89959.1 - 2.7e-50 171.2 0.0 4.1e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89959.1 - 2.6e-25 89.2 0.2 6.6e-24 84.6 0.2 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP89959.1 - 0.04 12.7 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase ISN1 PF06437.11 GAP89960.1 - 4e-199 661.7 0.0 4.5e-199 661.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Glyco_hydro_30C PF17189.4 GAP89961.1 - 0.045 14.0 0.3 0.079 13.2 0.3 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain IBN_N PF03810.19 GAP89962.1 - 1e-11 44.6 0.0 1.9e-09 37.3 0.0 3.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 GAP89962.1 - 9e-08 31.3 0.1 1e-06 27.9 0.0 2.2 1 1 0 2 2 2 1 Cse1 HEAT_2 PF13646.6 GAP89962.1 - 0.00055 20.3 1.2 0.3 11.5 0.3 3.1 2 0 0 2 2 2 2 HEAT repeats Xpo1 PF08389.12 GAP89962.1 - 0.00069 19.7 2.3 0.033 14.3 0.0 3.9 4 0 0 4 4 4 1 Exportin 1-like protein CAS_CSE1 PF03378.15 GAP89962.1 - 0.0015 17.1 0.0 0.0048 15.5 0.0 1.8 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cnd1 PF12717.7 GAP89962.1 - 0.083 12.9 0.2 0.45 10.6 0.1 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAP89962.1 - 0.14 12.5 1.7 2.3 8.7 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat IMS PF00817.20 GAP89965.1 - 2.2e-42 144.6 0.0 2.9e-41 141.0 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family zf_UBZ PF18439.1 GAP89965.1 - 1.5e-11 43.7 1.0 2.9e-11 42.7 1.0 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 GAP89965.1 - 2.4e-10 41.1 0.0 7.1e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 GAP89965.1 - 0.00033 20.8 0.0 0.00079 19.6 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DHHC PF01529.20 GAP89966.1 - 2.5e-27 95.6 1.4 2.5e-27 95.6 1.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase COX4_pro_2 PF07835.12 GAP89966.1 - 0.019 15.1 1.1 0.019 15.1 1.1 3.0 4 0 0 4 4 4 0 Bacterial aa3 type cytochrome c oxidase subunit IV Peptidase_S8 PF00082.22 GAP89968.1 - 5.5e-25 88.2 12.2 5.5e-25 88.2 12.2 2.1 2 1 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 GAP89968.1 - 3.7e-07 30.7 0.3 2.9e-06 27.9 0.3 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 TraP PF07296.11 GAP89968.1 - 0.17 11.1 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 TraP protein Dioxygenase_C PF00775.21 GAP89971.1 - 4.7e-40 136.9 0.0 6.7e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 GAP89971.1 - 1.6e-26 92.0 0.2 4.9e-16 58.4 0.2 2.3 2 0 0 2 2 2 2 Catechol dioxygenase N terminus DUF2052 PF09747.9 GAP89972.1 - 1.6e-25 90.4 8.8 1.1e-24 87.6 8.8 1.9 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) pKID PF02173.17 GAP89972.1 - 0.27 10.7 3.1 0.86 9.1 3.1 1.8 1 0 0 1 1 1 0 pKID domain DUF2293 PF10056.9 GAP89973.1 - 4.1e-28 97.4 1.5 9.7e-28 96.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) DUF4658 PF15555.6 GAP89973.1 - 0.042 14.0 2.1 0.12 12.6 2.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) CBP_CCPA PF17040.5 GAP89973.1 - 0.75 10.4 11.4 0.39 11.3 7.6 2.4 1 1 1 2 2 2 0 Cellulose-complementing protein A ABM PF03992.16 GAP89974.1 - 0.067 13.3 0.0 1.4 9.1 0.0 2.4 2 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase K_trans PF02705.16 GAP89975.1 - 2.4e-176 587.4 15.8 2.8e-176 587.2 15.8 1.0 1 0 0 1 1 1 1 K+ potassium transporter YjeF_N PF03853.15 GAP89978.1 - 2.7e-38 131.5 0.0 4.1e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 GAP89978.1 - 2.1e-11 44.6 0.0 8.1e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 FDF domain PT PF04886.12 GAP89978.1 - 0.005 16.4 16.5 0.005 16.4 16.5 3.1 3 0 0 3 3 3 1 PT repeat Zn_clus PF00172.18 GAP89979.1 - 2.6e-07 30.7 11.8 4.3e-07 30.0 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YEATS PF03366.16 GAP89980.1 - 1.5e-22 79.4 0.2 3.2e-22 78.3 0.2 1.6 1 0 0 1 1 1 1 YEATS family BET PF17035.5 GAP89980.1 - 0.0005 20.2 0.4 0.0014 18.8 0.3 1.8 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation SAM_2 PF07647.17 GAP89981.1 - 1.6e-14 53.8 0.0 2.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 GAP89981.1 - 8e-13 48.6 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 GAP89981.1 - 7.9e-11 42.5 0.0 1.6e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 GAP89981.1 - 0.073 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Aminotran_1_2 PF00155.21 GAP89982.1 - 5.5e-58 196.9 0.0 8.3e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 GAP89982.1 - 0.039 13.2 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 GAP89982.1 - 0.053 12.5 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V AMP-binding PF00501.28 GAP89983.1 - 2.7e-46 158.0 0.0 3.2e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GAP89983.1 - 3.6e-09 36.4 0.6 9e-09 35.1 0.1 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 GAP89983.1 - 0.0064 17.5 0.1 0.024 15.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain A_deaminase PF00962.22 GAP89984.1 - 6.1e-33 114.5 0.0 6.9e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase 3HCDH_RFF PF18321.1 GAP89984.1 - 0.1 13.0 1.0 0.24 11.9 1.0 1.6 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain WD40 PF00400.32 GAP89985.1 - 2.9e-37 126.0 19.4 3.1e-07 31.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP89985.1 - 5.9e-14 52.1 0.1 0.00025 21.3 0.1 4.6 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP89985.1 - 9e-05 21.6 0.1 0.97 8.3 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 GAP89985.1 - 0.00011 22.1 0.0 0.099 12.5 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 GAP89985.1 - 0.0031 16.9 0.0 0.26 10.6 0.0 2.8 1 1 1 2 2 2 2 WD40-like domain Phosducin PF02114.16 GAP89986.1 - 3.3e-14 52.5 0.0 2.3e-12 46.4 0.0 2.4 1 1 0 1 1 1 1 Phosducin SCA7 PF08313.12 GAP89988.1 - 9.1e-32 108.8 0.2 2.5e-31 107.4 0.2 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.14 GAP89988.1 - 0.25 9.6 10.8 0.33 9.2 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3128 PF11326.8 GAP89988.1 - 6.2 7.3 6.1 4 7.9 4.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) Mito_carr PF00153.27 GAP89989.1 - 3.7e-41 139.0 0.0 3.8e-13 49.2 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein zf-RING_UBOX PF13445.6 GAP89990.1 - 8.3e-07 28.9 9.5 0.0009 19.2 2.5 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-NOSIP PF15906.5 GAP89990.1 - 2.5e-06 27.5 0.0 5.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 GAP89990.1 - 1.6e-05 24.4 0.8 1.6e-05 24.4 0.8 2.7 2 1 1 3 3 3 1 Rtf2 RING-finger zf-RING_2 PF13639.6 GAP89990.1 - 3.8e-05 23.9 15.1 0.00055 20.2 3.4 2.9 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 GAP89990.1 - 4.1e-05 23.4 13.4 0.0043 16.9 0.7 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP89990.1 - 5.9e-05 22.8 13.9 0.00067 19.5 4.2 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP89990.1 - 0.00028 20.7 14.6 0.0025 17.6 1.5 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP89990.1 - 0.00075 19.4 4.0 0.00075 19.4 4.0 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 GAP89990.1 - 0.0044 17.1 13.4 0.27 11.4 1.6 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING FYVE PF01363.21 GAP89990.1 - 0.027 14.6 2.2 0.027 14.6 2.2 3.1 2 2 0 2 2 2 0 FYVE zinc finger zf-C3HC4_5 PF17121.5 GAP89990.1 - 0.055 13.4 0.7 0.15 12.0 0.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Borrelia_P83 PF05262.11 GAP89990.1 - 3 6.2 9.8 4.5 5.7 9.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Prok-RING_4 PF14447.6 GAP89990.1 - 4.5 7.2 21.6 1.6 8.6 7.7 3.6 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 DUF4407 PF14362.6 GAP89990.1 - 7 5.9 6.7 11 5.3 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Acyltransferase PF01553.21 GAP89991.1 - 3.3e-12 46.2 0.0 5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 GAP89992.1 - 2.1e-76 256.8 0.0 2.5e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP89992.1 - 4.7e-37 127.7 0.0 6.3e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAP89992.1 - 0.0036 16.3 0.0 0.043 12.8 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAP89992.1 - 0.1 12.5 0.6 0.24 11.3 0.0 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Septin PF00735.18 GAP89993.1 - 2.9e-14 53.0 0.0 3.2e-13 49.6 0.0 2.0 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAP89993.1 - 0.002 18.2 0.0 0.0091 16.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAP89993.1 - 0.0029 17.2 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain TsaE PF02367.17 GAP89993.1 - 0.031 14.3 0.0 0.098 12.7 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 GAP89993.1 - 0.032 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PAP_central PF04928.17 GAP89994.1 - 3e-107 357.2 0.0 4.1e-107 356.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 GAP89994.1 - 8.7e-62 207.7 0.3 1.6e-61 206.9 0.3 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 GAP89994.1 - 1.3e-09 38.2 0.0 2.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 GAP89994.1 - 0.043 13.6 0.1 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain WAC_Acf1_DNA_bd PF10537.9 GAP89995.1 - 4.4e-40 136.3 0.9 1e-39 135.1 0.0 2.1 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 GAP89995.1 - 4e-19 68.9 0.1 4e-19 68.9 0.1 2.6 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 GAP89995.1 - 6.3e-18 64.8 0.8 9.5e-18 64.3 0.2 1.7 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 GAP89995.1 - 3.3e-09 36.1 0.1 1.7e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Alg6_Alg8 PF03155.15 GAP89996.1 - 4.2e-175 583.4 32.2 4.9e-175 583.1 32.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Bromodomain PF00439.25 GAP89997.1 - 2.1e-23 82.2 0.5 4e-23 81.3 0.5 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.7 GAP89997.1 - 1.2e-07 31.7 0.3 5.8e-07 29.5 0.1 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP89997.1 - 1.4e-07 31.7 0.0 2.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP89997.1 - 0.00026 21.4 0.3 0.00062 20.1 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MYEOV2 PF15004.6 GAP89997.1 - 0.023 15.2 0.1 0.045 14.2 0.1 1.5 1 0 0 1 1 1 0 Myeloma-overexpressed-like Retinal PF15449.6 GAP89997.1 - 0.13 10.0 1.3 0.2 9.4 1.3 1.2 1 0 0 1 1 1 0 Retinal protein Lectin_leg-like PF03388.13 GAP89998.1 - 1.3e-20 73.8 0.0 3.3e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Legume-like lectin family Spt20 PF12090.8 GAP89998.1 - 0.0018 17.9 22.8 0.0036 16.9 22.8 1.4 1 0 0 1 1 1 1 Spt20 family DUF5523 PF17661.1 GAP89998.1 - 0.011 15.4 4.7 0.019 14.7 4.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Connexin40_C PF16791.5 GAP89998.1 - 0.034 15.4 6.7 0.097 14.0 6.7 1.8 1 0 0 1 1 1 0 Connexin 40 C-terminal domain TFIIA PF03153.13 GAP89998.1 - 0.061 13.3 21.6 0.083 12.9 21.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC-167 PF15188.6 GAP89998.1 - 0.083 13.2 0.8 1.8 9.0 1.6 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Macoilin PF09726.9 GAP89998.1 - 0.14 10.7 16.8 0.18 10.3 16.8 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_S64 PF08192.11 GAP89998.1 - 1.3 7.4 17.5 1.9 6.9 17.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 OmpH PF03938.14 GAP89998.1 - 1.8 8.9 20.4 0.7 10.2 1.0 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FAM76 PF16046.5 GAP89998.1 - 3.7 6.8 18.9 5.8 6.2 18.9 1.2 1 0 0 1 1 1 0 FAM76 protein CPSF100_C PF13299.6 GAP89998.1 - 4.7 7.4 13.2 2.2 8.5 10.7 1.7 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TMEM51 PF15345.6 GAP89998.1 - 5.9 6.6 10.5 5 6.9 9.1 1.5 2 0 0 2 2 2 0 Transmembrane protein 51 Peptidase_M24 PF00557.24 GAP89999.1 - 6.7e-57 192.5 0.1 8.7e-57 192.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAP89999.1 - 2.6e-18 65.9 0.0 6.8e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Fungal_trans PF04082.18 GAP90000.1 - 8.7e-32 110.2 0.0 1.4e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP90000.1 - 4.8e-11 42.6 13.8 7.9e-11 41.9 13.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DPM3 PF08285.11 GAP90000.1 - 0.088 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Band_7 PF01145.25 GAP90000.1 - 0.42 10.6 3.4 1.2 9.1 1.3 2.2 2 0 0 2 2 2 0 SPFH domain / Band 7 family Prok-E2_A PF14457.6 GAP90000.1 - 0.67 9.6 3.1 5 6.7 0.3 2.7 3 0 0 3 3 3 0 Prokaryotic E2 family A Methyltr_RsmB-F PF01189.17 GAP90001.1 - 6.9e-17 61.7 0.0 5.3e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DUF5024 PF16427.5 GAP90001.1 - 0.023 15.0 0.0 0.066 13.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) DUF1996 PF09362.10 GAP90002.1 - 5.9e-66 222.8 0.8 8.1e-66 222.4 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gtr1_RagA PF04670.12 GAP90003.1 - 3.2e-70 236.1 0.0 3.9e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 GAP90003.1 - 0.0014 18.1 0.0 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 GAP90003.1 - 0.011 16.1 0.0 0.034 14.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 GAP90003.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 GAP90003.1 - 0.079 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MIF PF01187.18 GAP90004.1 - 1.6e-09 38.1 0.0 2.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) ABM PF03992.16 GAP90007.1 - 2.6e-09 37.1 0.1 3.2e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase LCAT PF02450.15 GAP90008.1 - 0.00072 18.8 0.0 0.001 18.3 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 GAP90008.1 - 0.0032 18.1 0.6 0.0032 18.1 0.6 2.5 3 1 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP90008.1 - 0.0038 16.5 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 GAP90008.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 GAP90008.1 - 0.064 13.1 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF3246 PF11596.8 GAP90008.1 - 0.074 12.5 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) GST_N PF02798.20 GAP90009.1 - 4.7e-11 42.9 0.0 8.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAP90009.1 - 9.7e-08 32.1 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAP90009.1 - 1.3e-06 28.6 0.0 2.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAP90009.1 - 6.7e-06 26.4 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP90009.1 - 6.6e-05 22.9 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAP90009.1 - 0.00013 22.2 0.0 0.00028 21.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 GAP90009.1 - 0.054 14.1 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SAP18 PF06487.12 GAP90012.1 - 4.9e-35 120.7 0.0 5.4e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 GAP90013.1 - 1.9e-52 177.1 0.0 1.9e-52 177.1 0.0 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 GAP90013.1 - 7.6e-10 38.2 8.2 7.6e-10 38.2 8.2 2.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like LEM PF03020.15 GAP90013.1 - 0.088 12.4 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 LEM domain Amidohydro_2 PF04909.14 GAP90013.1 - 0.14 11.9 4.3 0.23 11.2 4.3 1.4 1 0 0 1 1 1 0 Amidohydrolase DUF966 PF06136.13 GAP90013.1 - 7.6 6.2 16.2 11 5.6 15.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF966) RPN7 PF10602.9 GAP90014.1 - 3e-36 124.7 0.0 4.8e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GAP90014.1 - 1.4e-14 54.5 0.4 3.3e-14 53.3 0.4 1.7 1 0 0 1 1 1 1 PCI domain MFS_1 PF07690.16 GAP90015.1 - 2.3e-36 125.5 41.1 2.3e-36 125.5 41.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PCMT PF01135.19 GAP90016.1 - 1.1e-40 139.7 0.0 6e-26 91.5 0.0 2.3 2 1 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GAP90016.1 - 0.067 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 GAP90016.1 - 0.22 11.5 0.0 0.35 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF2235 PF09994.9 GAP90018.1 - 3.4e-31 108.7 0.1 3.8e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SAB PF04382.13 GAP90019.1 - 0.046 13.8 0.1 0.09 12.9 0.1 1.5 1 0 0 1 1 1 0 SAB domain MMR_HSR1 PF01926.23 GAP90021.1 - 2e-08 34.3 2.2 3.1e-08 33.7 0.6 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAP90021.1 - 1.9e-06 27.3 0.7 1.9e-06 27.3 0.7 1.7 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 GAP90021.1 - 3.4e-05 23.8 0.2 0.00052 20.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 GAP90021.1 - 6.5e-05 23.5 0.8 0.00072 20.1 0.1 2.4 2 0 0 2 2 2 1 ABC transporter FeoB_N PF02421.18 GAP90021.1 - 0.0001 21.9 0.3 0.00021 20.8 0.3 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 GAP90021.1 - 0.00015 21.0 0.7 0.0029 16.8 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 GAP90021.1 - 0.0028 17.7 9.8 0.53 10.3 0.2 3.8 2 2 1 3 3 3 2 Dynamin family Septin PF00735.18 GAP90021.1 - 0.0036 16.6 1.0 0.047 13.0 0.2 2.4 2 0 0 2 2 2 1 Septin Jnk-SapK_ap_N PF09744.9 GAP90021.1 - 0.0062 16.8 7.2 0.013 15.7 6.1 2.2 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 FH2 PF02181.23 GAP90021.1 - 0.0071 15.5 1.6 0.029 13.5 1.6 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Fmp27_WPPW PF10359.9 GAP90021.1 - 0.027 13.3 1.8 0.038 12.8 1.8 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ran-binding PF05508.11 GAP90021.1 - 0.057 12.4 1.2 0.092 11.7 1.2 1.3 1 0 0 1 1 1 0 RanGTP-binding protein AAA_22 PF13401.6 GAP90021.1 - 0.077 13.3 1.0 0.65 10.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAP90021.1 - 0.077 13.4 1.1 0.62 10.4 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain UPF0242 PF06785.11 GAP90021.1 - 0.092 12.8 7.7 0.16 12.0 7.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PV-1 PF06637.11 GAP90021.1 - 0.1 11.4 8.2 0.16 10.8 8.2 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Phage_GPO PF05929.11 GAP90021.1 - 0.11 12.1 2.2 0.18 11.4 2.2 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF745 PF05335.13 GAP90021.1 - 0.22 11.2 4.7 0.086 12.6 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) LPD5 PF18799.1 GAP90021.1 - 0.28 11.6 4.2 4.6 7.6 4.2 2.6 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 5 OmpH PF03938.14 GAP90021.1 - 0.52 10.7 11.5 1.4 9.3 11.5 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) eIF-4B PF06273.11 GAP90021.1 - 0.52 9.3 6.1 0.9 8.5 6.1 1.3 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B 5_nucleotid PF05761.14 GAP90021.1 - 0.66 8.8 3.9 1.2 7.9 3.9 1.4 1 0 0 1 1 1 0 5' nucleotidase family FUSC-like PF12805.7 GAP90021.1 - 1.8 7.6 4.8 2.9 6.9 4.8 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF4484 PF14831.6 GAP90021.1 - 2.1 8.4 5.6 9.8 6.2 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) FlxA PF14282.6 GAP90021.1 - 2.7 8.0 10.7 4.5 7.3 8.8 2.4 2 0 0 2 2 2 0 FlxA-like protein DUF1451 PF07295.11 GAP90021.1 - 3.1 7.8 6.5 1.1 9.2 1.5 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain NmrA PF05368.13 GAP90023.1 - 2.8e-27 95.8 0.0 4.2e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP90023.1 - 4.5e-16 59.3 0.3 7.6e-16 58.5 0.3 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP90023.1 - 0.011 15.2 0.0 0.04 13.4 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAP90023.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain DUF4719 PF15843.5 GAP90023.1 - 0.064 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Serglycin PF04360.12 GAP90023.1 - 0.11 12.5 0.9 0.17 11.8 0.9 1.2 1 0 0 1 1 1 0 Serglycin Methyltransf_2 PF00891.18 GAP90025.1 - 1.3e-23 83.4 0.0 2.1e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain D123 PF07065.14 GAP90026.1 - 4.3e-115 384.1 0.0 5e-115 383.9 0.0 1.0 1 0 0 1 1 1 1 D123 cwf21 PF08312.12 GAP90027.1 - 3.2e-09 36.8 8.7 3.2e-09 36.8 8.7 1.8 2 1 0 2 2 2 1 cwf21 domain DUF1640 PF07798.11 GAP90028.1 - 6.3e-44 150.1 5.3 8.7e-44 149.6 5.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Prominin PF05478.11 GAP90028.1 - 0.041 11.8 2.2 0.055 11.4 2.2 1.1 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 GAP90028.1 - 1.1 9.3 8.2 0.22 11.6 3.2 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HET PF06985.11 GAP90029.1 - 3.3e-25 89.2 0.0 6.3e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cytochrom_B561 PF03188.16 GAP90030.1 - 0.00018 21.7 4.3 0.00018 21.7 4.3 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 GAP90030.1 - 0.87 9.7 8.6 2.1 8.5 1.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Nnf1 PF03980.14 GAP90031.1 - 3e-35 120.9 0.4 3e-35 120.9 0.4 2.6 2 1 0 2 2 1 1 Nnf1 SHE3 PF17078.5 GAP90031.1 - 0.01 15.5 0.2 0.01 15.5 0.2 2.5 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 ADIP PF11559.8 GAP90031.1 - 0.049 13.7 0.7 0.049 13.7 0.7 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding SOG2 PF10428.9 GAP90031.1 - 0.15 11.2 10.5 0.18 11.0 10.5 1.2 1 1 0 1 1 1 0 RAM signalling pathway protein CENP-K PF11802.8 GAP90031.1 - 0.17 11.4 0.0 0.17 11.4 0.0 2.5 3 0 0 3 3 3 0 Centromere-associated protein K MSP1_C PF07462.11 GAP90031.1 - 0.29 9.8 1.5 0.37 9.4 1.5 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF16 PF01519.16 GAP90031.1 - 2.2 8.8 15.0 0.97 9.9 2.9 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF16 Ndc1_Nup PF09531.10 GAP90031.1 - 2.8 6.5 5.0 3.6 6.2 5.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FmiP_Thoc5 PF09766.9 GAP90031.1 - 5.4 6.2 11.3 6.5 5.9 0.2 2.2 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 TerB_C PF15615.6 GAP90031.1 - 6 7.1 11.0 1.5 9.1 3.7 2.6 2 1 1 3 3 3 0 TerB-C domain Presenilin PF01080.17 GAP90031.1 - 8.7 5.0 7.3 13 4.4 7.3 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 GAP90031.1 - 9 5.8 17.2 0.39 10.3 11.0 1.7 2 0 0 2 2 2 0 Spt20 family NTF2 PF02136.20 GAP90032.1 - 1.2e-23 83.9 1.1 1.9e-23 83.3 1.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 GAP90032.1 - 6.9e-05 22.6 0.1 0.00012 21.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5305 PF17231.2 GAP90033.1 - 0.035 13.5 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Syndecan PF01034.20 GAP90033.1 - 0.11 12.4 0.6 0.2 11.6 0.6 1.4 1 0 0 1 1 1 0 Syndecan domain Granulin PF00396.18 GAP90033.1 - 1.1 9.6 15.3 1.4 9.3 2.6 3.2 3 0 0 3 3 3 0 Granulin SOG2 PF10428.9 GAP90033.1 - 1.7 7.7 5.6 2 7.5 5.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2613 PF11021.8 GAP90033.1 - 2.5 8.3 7.0 0.34 11.1 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2613) Fungal_trans_2 PF11951.8 GAP90034.1 - 0.0014 17.5 0.0 0.0029 16.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ACTH_domain PF00976.18 GAP90034.1 - 5.5 7.0 6.8 0.7 9.9 0.5 2.4 2 0 0 2 2 2 0 Corticotropin ACTH domain Cad PF03596.13 GAP90035.1 - 1.8e-18 67.1 11.6 3.1e-18 66.4 11.6 1.3 1 0 0 1 1 1 1 Cadmium resistance transporter CopD PF05425.13 GAP90035.1 - 0.051 14.0 0.0 0.051 14.0 0.0 2.2 3 0 0 3 3 3 0 Copper resistance protein D Ran_BP1 PF00638.18 GAP90036.1 - 3.6e-42 143.5 0.5 6.8e-42 142.6 0.5 1.4 1 0 0 1 1 1 1 RanBP1 domain CDC27 PF09507.10 GAP90036.1 - 0.59 9.5 25.7 0.02 14.3 7.3 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF4211 PF13926.6 GAP90037.1 - 1.7e-45 154.6 0.0 1.7e-44 151.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Pep1_7 PF17232.2 GAP90037.1 - 3.3 8.2 7.2 18 5.9 1.0 3.3 2 0 0 2 2 2 0 Elicitor peptide 1-7 IGPS PF00218.21 GAP90038.1 - 4.1e-96 321.1 0.1 5.8e-96 320.5 0.1 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 GAP90038.1 - 1.8e-46 158.3 0.0 3e-45 154.3 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.22 GAP90038.1 - 2.5e-40 138.3 0.0 1.6e-39 135.7 0.0 2.1 2 0 0 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 GAP90038.1 - 0.00045 20.0 0.6 0.0025 17.6 0.6 2.0 1 1 0 1 1 1 1 Peptidase C26 NanE PF04131.14 GAP90038.1 - 0.089 12.0 0.1 0.79 8.9 0.1 2.1 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Peripla_BP_2 PF01497.18 GAP90038.1 - 0.096 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein FMN_dh PF01070.18 GAP90038.1 - 0.1 11.6 0.1 0.2 10.6 0.1 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Nup188_C PF18378.1 GAP90039.1 - 5.3e-138 459.9 0.1 9.5e-138 459.0 0.1 1.4 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 GAP90039.1 - 3.6e-55 187.4 0.1 2.3e-38 131.8 0.0 3.4 3 1 0 3 3 3 2 Nucleoporin subcomplex protein binding to Pom34 AAA PF00004.29 GAP90040.1 - 4.4e-18 66.0 0.0 7.9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP90040.1 - 2.2e-05 24.9 0.0 8.3e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAP90040.1 - 0.001 19.1 0.0 0.003 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP90040.1 - 0.0042 17.4 0.2 0.032 14.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 GAP90040.1 - 0.036 13.3 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain RuvB_N PF05496.12 GAP90040.1 - 0.048 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Hydin_ADK PF17213.3 GAP90040.1 - 0.16 12.2 2.4 0.19 12.0 0.1 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain zf-Tim10_DDP PF02953.15 GAP90041.1 - 1e-18 66.7 5.2 1.3e-18 66.4 5.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 GAP90041.1 - 0.039 13.6 3.3 0.19 11.4 3.3 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Peptidase_C12 PF01088.21 GAP90042.1 - 2.6e-53 180.9 0.0 2.9e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RL10P_insert PF17777.1 GAP90043.1 - 3.6e-19 68.5 0.0 5.4e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 GAP90043.1 - 0.0007 19.7 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.8 GAP90044.1 - 1.3e-24 86.7 1.8 1.3e-24 86.7 1.8 2.1 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 GAP90044.1 - 2e-16 59.5 0.1 9.4e-16 57.4 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAP90044.1 - 0.00029 20.9 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Pkinase PF00069.25 GAP90045.1 - 1.6e-08 34.3 0.0 2.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAP90045.1 - 0.0028 17.6 0.1 0.0067 16.4 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 GAP90045.1 - 0.0033 16.7 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 GAP90045.1 - 0.035 13.7 0.1 4.8 6.8 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAP90045.1 - 0.095 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family L51_S25_CI-B8 PF05047.16 GAP90046.1 - 1.7e-15 56.6 0.0 2.5e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.18 GAP90047.1 - 5.3e-87 291.2 0.2 6.1e-87 291.0 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase BP28CT PF08146.12 GAP90048.1 - 6.9e-43 146.2 1.8 1.5e-42 145.2 0.9 2.2 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 GAP90048.1 - 5.9e-25 87.9 7.8 1.7e-24 86.4 0.1 5.0 4 1 1 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 GAP90048.1 - 7.8e-07 28.8 5.7 0.11 12.8 0.0 6.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 GAP90048.1 - 0.00031 21.1 5.3 1.2 9.6 0.4 5.7 5 1 0 5 5 5 1 HEAT repeats DUF4042 PF13251.6 GAP90048.1 - 0.07 12.8 0.5 14 5.3 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 GAP90048.1 - 2 9.0 9.3 9.8 6.8 0.0 5.9 8 0 0 8 8 8 0 HEAT-like repeat Lipase_GDSL_2 PF13472.6 GAP90049.1 - 4e-22 79.5 0.0 5.3e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP90049.1 - 5.3e-12 46.1 0.0 6.5e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 GAP90049.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF919 PF06034.11 GAP90050.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Bgal_small_N PF02929.17 GAP90050.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Beta galactosidase small chain TMP-TENI PF02581.17 GAP90051.1 - 3.5e-58 195.9 3.2 4.3e-58 195.6 3.2 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase HK PF02110.15 GAP90051.1 - 1.2e-05 24.9 0.0 2.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Isochorismatase PF00857.20 GAP90052.1 - 3.1e-24 86.1 0.0 8.1e-24 84.7 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family Glyco_trans_4_4 PF13579.6 GAP90052.1 - 0.00092 19.7 1.4 0.15 12.5 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 GAP90052.1 - 0.048 13.6 0.2 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_hydr_30_2 PF14587.6 GAP90053.1 - 1.4e-11 44.7 1.8 1.4e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 GAP90053.1 - 3e-11 43.4 5.5 1e-10 41.6 5.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 GAP90053.1 - 1.8e-06 27.4 1.8 2.3e-05 23.8 1.8 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30 PF02055.16 GAP90053.1 - 0.00081 18.5 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Aminotran_1_2 PF00155.21 GAP90054.1 - 3.8e-83 279.7 0.0 4.7e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 GAP90054.1 - 4.6e-05 22.1 0.0 7.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 GAP90054.1 - 0.00028 20.0 0.0 0.0012 17.9 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 GAP90054.1 - 0.00067 19.1 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Acyltransferase PF01553.21 GAP90056.1 - 3.7e-34 117.2 0.0 5.8e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4281 PF14108.6 GAP90056.1 - 0.0067 16.8 2.2 0.014 15.7 2.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) ABC2_membrane_3 PF12698.7 GAP90056.1 - 0.59 9.2 8.2 0.89 8.6 8.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein HEAT PF02985.22 GAP90058.1 - 8.5e-06 25.6 4.5 0.27 11.6 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 GAP90058.1 - 0.0023 18.3 2.7 0.49 10.8 0.2 5.0 4 1 1 5 5 5 2 HEAT repeats Cnd1 PF12717.7 GAP90058.1 - 0.022 14.8 0.0 0.16 12.0 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 GAP90058.1 - 0.11 13.1 0.3 1.9 9.1 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat mRNA_cap_enzyme PF01331.19 GAP90059.1 - 7.2e-55 185.9 0.1 9.4e-55 185.5 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 GAP90059.1 - 1.6e-32 112.4 0.0 2.4e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 GAP90059.1 - 1.5e-07 31.3 0.0 0.00014 21.6 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 GAP90059.1 - 0.035 14.4 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA ligase Glyco_hydro_3_C PF01915.22 GAP90060.1 - 6.8e-50 169.9 0.0 1.3e-49 168.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAP90060.1 - 3.2e-34 118.8 0.0 5.6e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAP90060.1 - 4e-15 55.7 0.0 7.1e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain ATG16 PF08614.11 GAP90061.1 - 0.00059 20.1 0.0 0.00059 20.1 0.0 3.3 2 2 2 4 4 4 1 Autophagy protein 16 (ATG16) Vac_Fusion PF02346.16 GAP90061.1 - 0.034 13.8 0.5 1.5 8.5 0.1 3.6 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 TMCO5 PF14992.6 GAP90061.1 - 0.085 12.4 0.5 0.24 11.0 0.5 1.8 1 0 0 1 1 1 0 TMCO5 family Baculo_PEP_C PF04513.12 GAP90061.1 - 0.15 12.1 0.2 24 5.0 0.0 3.3 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 GAP90061.1 - 0.77 10.3 6.8 5.8 7.5 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function DUF16 SlyX PF04102.12 GAP90061.1 - 4.5 8.0 15.2 1.3 9.7 0.5 5.1 4 1 1 5 5 5 0 SlyX Trimer_CC PF08954.11 GAP90061.1 - 6.4 6.4 7.0 0.71 9.5 1.2 2.5 2 0 0 2 2 2 0 Trimerisation motif 14-3-3 PF00244.20 GAP90062.1 - 0.13 11.7 0.5 0.21 11.1 0.5 1.2 1 0 0 1 1 1 0 14-3-3 protein NIR_SIR_ferr PF03460.17 GAP90062.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain SKG6 PF08693.10 GAP90063.1 - 0.0021 17.4 0.7 0.005 16.2 0.7 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 GAP90063.1 - 0.0055 17.1 0.5 0.011 16.2 0.5 1.5 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin RNA_pol_I_A49 PF06870.12 GAP90065.1 - 3.9e-93 312.4 0.3 4.7e-93 312.1 0.3 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Tad PF13400.6 GAP90065.1 - 0.072 13.4 2.4 0.15 12.4 2.4 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like NUDE_C PF04880.13 GAP90065.1 - 0.59 10.6 11.2 0.09 13.2 5.4 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Abhydrolase_1 PF00561.20 GAP90066.1 - 7.3e-08 32.4 0.1 1.3e-07 31.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP90066.1 - 1.2e-05 24.7 0.2 1.6e-05 24.3 0.2 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 GAP90066.1 - 0.022 14.4 0.2 0.043 13.5 0.2 1.6 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 GAP90066.1 - 0.099 12.1 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans PF04082.18 GAP90067.1 - 7e-06 25.3 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP90067.1 - 0.0084 16.2 8.0 0.024 14.8 8.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1512 PF07431.12 GAP90068.1 - 0.095 11.7 1.0 0.14 11.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) AMP-binding PF00501.28 GAP90069.1 - 1.2e-289 959.8 0.1 3.9e-76 256.3 0.0 4.6 5 0 0 5 5 5 4 AMP-binding enzyme Condensation PF00668.20 GAP90069.1 - 2.4e-128 428.7 0.0 2.7e-37 128.5 0.0 5.8 5 1 0 5 5 5 4 Condensation domain PP-binding PF00550.25 GAP90069.1 - 2.3e-38 130.4 6.3 1.1e-09 38.5 1.3 5.1 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAP90069.1 - 2.4e-12 47.6 0.0 0.027 15.4 0.0 4.5 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain Amidinotransf PF02274.17 GAP90070.1 - 1e-07 31.4 0.0 0.00062 19.0 0.0 3.1 2 1 1 3 3 3 2 Amidinotransferase Cys_Met_Meta_PP PF01053.20 GAP90071.1 - 4.2e-30 104.6 0.0 5.2e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAP90071.1 - 0.0008 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II YqcI_YcgG PF08892.11 GAP90072.1 - 9.6e-36 123.6 0.0 1.4e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 YqcI/YcgG family PhyH PF05721.13 GAP90073.1 - 1.2e-14 55.1 0.1 2.8e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sulfotransfer_3 PF13469.6 GAP90073.1 - 7.4e-05 23.2 0.5 0.0024 18.3 0.1 2.7 2 1 1 3 3 3 1 Sulfotransferase family AraC_binding PF02311.19 GAP90073.1 - 0.0088 16.0 0.1 4.2 7.3 0.0 2.8 2 0 0 2 2 2 2 AraC-like ligand binding domain Arylsulfotran_2 PF14269.6 GAP90074.1 - 3.7e-49 167.7 0.1 4.8e-49 167.3 0.1 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 GAP90074.1 - 7.9e-16 57.9 0.4 3.5e-15 55.8 0.3 2.0 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) GATase_2 PF00310.21 GAP90075.1 - 4.4e-183 608.8 0.0 5.8e-183 608.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 GAP90075.1 - 2.9e-156 520.2 0.0 5e-156 519.5 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 GAP90075.1 - 1.8e-109 365.6 0.0 8.5e-108 360.1 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 GAP90075.1 - 3.7e-85 284.3 4.3 6e-85 283.6 4.3 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 GAP90075.1 - 2.2e-23 83.0 0.3 2.2e-22 79.7 0.3 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 GAP90075.1 - 1.6e-21 76.2 0.1 3.3e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 GAP90075.1 - 4.6e-09 36.4 0.0 1.6e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 GAP90075.1 - 6.6e-08 33.0 0.1 4.5e-05 23.9 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 GAP90075.1 - 7.7e-07 29.0 4.7 0.0015 18.2 0.2 3.0 4 0 0 4 4 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 GAP90075.1 - 1.2e-06 28.2 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 GAP90075.1 - 3.2e-05 23.3 1.5 0.021 14.1 0.0 3.7 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP90075.1 - 5.3e-05 22.1 0.1 5.3e-05 22.1 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FMO-like PF00743.19 GAP90075.1 - 0.00035 19.2 0.4 0.066 11.6 0.0 2.8 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 GAP90075.1 - 0.00039 19.7 0.1 0.0013 18.0 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 GAP90075.1 - 0.00051 19.2 0.1 0.0027 16.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 GAP90075.1 - 0.00099 18.6 0.1 0.002 17.5 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 GAP90075.1 - 0.003 18.0 0.9 1.9 9.0 0.1 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 GAP90075.1 - 0.0091 15.3 0.1 0.022 14.0 0.0 1.6 2 0 0 2 2 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.23 GAP90075.1 - 0.03 14.3 0.0 0.084 12.8 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMN_dh PF01070.18 GAP90075.1 - 0.036 13.1 0.5 0.12 11.4 0.5 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_binding_9 PF13454.6 GAP90075.1 - 0.13 12.3 0.0 0.51 10.3 0.0 2.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding MADF_DNA_bdg PF10545.9 GAP90075.1 - 0.14 12.5 1.0 0.47 10.8 1.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AlaDh_PNT_C PF01262.21 GAP90075.1 - 0.14 11.4 0.4 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 GAP90075.1 - 0.18 11.8 1.2 7.9 6.5 0.2 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Apc15p PF05841.11 GAP90076.1 - 2e-24 86.7 2.1 2e-24 86.7 2.1 3.0 3 0 0 3 3 3 2 Apc15p protein TFIIA PF03153.13 GAP90076.1 - 2.2e-05 24.7 26.4 2.2e-05 24.7 26.4 2.7 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 GAP90076.1 - 2.1 5.3 8.2 3 4.8 8.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Use1 PF09753.9 GAP90077.1 - 0.00015 21.6 0.0 0.00016 21.5 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 CHZ PF09649.10 GAP90078.1 - 5.2e-17 61.0 2.7 5.2e-17 61.0 2.7 2.2 2 0 0 2 2 2 1 Histone chaperone domain CHZ UPF0370 PF13980.6 GAP90079.1 - 0.034 14.2 0.6 0.057 13.5 0.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DUF2556 PF10831.8 GAP90079.1 - 0.23 11.4 1.2 0.39 10.7 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) Cyclin PF08613.11 GAP90080.1 - 1.5e-30 106.7 0.0 2.4e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 GAP90080.1 - 0.0025 17.6 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.23 GAP90081.1 - 4.2e-16 58.4 9.7 0.00019 21.3 0.1 7.8 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 GAP90081.1 - 0.00046 20.2 16.9 12 6.5 0.1 7.6 8 0 0 8 8 8 4 HEAT repeat IFRD PF05004.13 GAP90081.1 - 0.0029 16.8 0.1 0.0029 16.8 0.1 3.6 5 0 0 5 5 5 1 Interferon-related developmental regulator (IFRD) V-ATPase_H_C PF11698.8 GAP90081.1 - 0.0036 17.4 1.2 0.066 13.3 0.1 3.2 3 0 0 3 3 3 1 V-ATPase subunit H DUF747 PF05346.11 GAP90081.1 - 0.008 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF3361 PF11841.8 GAP90081.1 - 0.015 15.2 6.0 0.99 9.3 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) DDE_Tnp_2 PF04693.12 GAP90081.1 - 0.017 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 HEAT_EZ PF13513.6 GAP90081.1 - 0.026 15.1 7.7 13 6.5 0.1 6.9 7 0 0 7 7 7 0 HEAT-like repeat Ric8 PF10165.9 GAP90081.1 - 0.1 11.6 0.8 0.61 9.1 0.7 2.3 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Bac_rhodopsin PF01036.18 GAP90084.1 - 4.2e-24 85.4 17.6 5.1e-24 85.1 17.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein SET PF00856.28 GAP90085.1 - 0.0017 18.8 0.0 0.0025 18.2 0.0 1.2 1 0 0 1 1 1 1 SET domain DUF4834 PF16118.5 GAP90086.1 - 0.031 15.3 0.0 0.048 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Velvet PF11754.8 GAP90087.1 - 1.4e-48 166.0 0.0 1.3e-31 110.4 0.0 3.4 2 2 1 3 3 3 2 Velvet factor TCP PF03634.13 GAP90088.1 - 7 7.2 11.9 2.3 8.8 1.5 3.0 3 0 0 3 3 3 0 TCP family transcription factor Ank_5 PF13857.6 GAP90089.1 - 2.2e-13 50.1 0.0 1.1e-09 38.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.24 GAP90089.1 - 2.2e-12 46.9 0.3 8.7e-12 45.0 0.3 2.0 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.30 GAP90089.1 - 1.1e-11 44.6 0.0 2.1e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 GAP90089.1 - 1.6e-10 41.4 0.0 3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP90089.1 - 2.7e-09 36.5 0.0 0.00065 20.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 GAP90089.1 - 1.8e-08 34.7 0.0 4.3e-07 30.3 0.0 2.9 1 1 2 3 3 3 1 Ankyrin repeats (many copies) RHD_dimer PF16179.5 GAP90089.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Rel homology dimerisation domain Na_H_Exchanger PF00999.21 GAP90090.1 - 4.5e-39 134.3 13.8 1.6e-38 132.5 13.8 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Tetraspanin PF00335.20 GAP90090.1 - 5.9 6.5 7.6 1 9.0 1.4 2.4 2 0 0 2 2 2 0 Tetraspanin family Cauli_VI PF01693.16 GAP90091.1 - 1.8e-38 130.6 7.3 4.8e-21 74.8 1.4 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 GAP90091.1 - 2.2e-33 115.4 0.0 3.7e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Mucin PF01456.17 GAP90091.1 - 1 9.4 6.1 2.2 8.3 6.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein dCMP_cyt_deam_1 PF00383.23 GAP90092.1 - 8.7e-10 38.4 0.0 5.3e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAP90092.1 - 4.8e-05 23.1 0.1 0.00011 21.9 0.1 1.5 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 GAP90092.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase 6PF2K PF01591.18 GAP90093.1 - 9.2e-65 218.1 0.0 3.2e-44 150.9 0.0 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAP90093.1 - 8e-28 97.5 0.1 2e-23 83.1 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAP90093.1 - 0.0077 16.4 0.0 0.088 13.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAP90093.1 - 0.021 14.3 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RHD3 PF05879.12 GAP90094.1 - 0 1047.5 0.0 0 1047.2 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 GAP90094.1 - 2.4e-08 33.6 0.3 4.1e-08 32.8 0.3 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 GAP90094.1 - 1.6e-06 28.3 0.0 2.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 GAP90094.1 - 3.4e-05 23.9 0.1 7.1e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 GAP90094.1 - 0.0024 18.1 1.3 0.0056 16.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 GAP90094.1 - 0.074 12.3 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Septin Cys_Met_Meta_PP PF01053.20 GAP90094.1 - 0.096 11.2 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RNase_HII PF01351.18 GAP90095.1 - 3e-44 151.2 0.0 6.6e-39 133.8 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease HII Ribosomal_60s PF00428.19 GAP90095.1 - 0.0097 16.5 9.8 0.026 15.1 9.8 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein Mif2_N PF15624.6 GAP90096.1 - 3.2e-37 128.3 2.1 3.2e-37 128.3 2.1 3.5 2 1 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 GAP90096.1 - 4.6e-16 58.8 0.1 1.6e-12 47.5 0.0 2.4 1 1 1 2 2 2 2 Mif2/CENP-C like RNA12 PF10443.9 GAP90097.1 - 8.4e-159 529.0 0.9 5e-158 526.5 0.4 1.9 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 GAP90097.1 - 6.6e-06 25.8 0.0 6.4e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 GAP90097.1 - 0.0002 21.4 0.2 0.00092 19.2 0.2 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 GAP90097.1 - 0.0015 18.6 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) Tail_VII PF17091.5 GAP90097.1 - 0.24 11.3 1.1 0.58 10.1 1.1 1.5 1 0 0 1 1 1 0 Inovirus G7P protein DUF3128 PF11326.8 GAP90098.1 - 2.6e-25 88.6 0.3 4e-25 88.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) HSP70 PF00012.20 GAP90099.1 - 2.2e-256 851.8 4.8 2.6e-256 851.6 4.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAP90099.1 - 2.4e-17 62.8 0.2 5.5e-16 58.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 GAP90099.1 - 0.0092 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Actin PF00022.19 GAP90099.1 - 0.031 12.9 0.0 0.71 8.4 0.0 2.2 2 0 0 2 2 2 0 Actin FtsA PF14450.6 GAP90099.1 - 0.032 14.7 2.0 11 6.5 0.1 3.3 3 2 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 GAP90099.1 - 0.039 13.2 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.18 GAP90099.1 - 0.042 13.1 0.1 0.088 12.1 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase OPT PF03169.15 GAP90100.1 - 3.5e-142 475.2 31.6 4.4e-142 474.9 31.6 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DLH PF01738.18 GAP90100.1 - 3.1e-26 92.3 0.0 4.6e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 GAP90100.1 - 0.0034 17.0 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Phage_holin_2_1 PF04971.12 GAP90100.1 - 5.4 7.1 6.9 0.52 10.4 0.3 2.7 3 0 0 3 3 3 0 Bacteriophage P21 holin S HD PF01966.22 GAP90101.1 - 5.6e-06 26.6 0.0 8.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 GAP90101.1 - 0.034 13.6 0.2 0.055 12.9 0.2 1.2 1 0 0 1 1 1 0 HDOD domain GluR_Homer-bdg PF10606.9 GAP90101.1 - 0.19 12.0 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor Mucin PF01456.17 GAP90102.1 - 0.0045 17.0 10.9 0.0074 16.3 10.9 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein PAN_1 PF00024.26 GAP90102.1 - 2 8.4 6.2 0.2 11.6 1.5 1.7 2 0 0 2 2 2 0 PAN domain Rav1p_C PF12234.8 GAP90103.1 - 5.7e-280 930.2 0.1 8.3e-280 929.7 0.1 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 GAP90103.1 - 0.024 15.5 4.5 28 5.8 0.1 5.7 6 0 0 6 6 6 0 WD domain, G-beta repeat Peptidase_S39 PF02122.15 GAP90103.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase S39 Sfi1 PF08457.10 GAP90104.1 - 2.1e-25 89.3 76.8 5.5e-15 54.9 46.3 5.2 3 2 1 4 4 4 3 Sfi1 spindle body protein tRNA-synt_1 PF00133.22 GAP90105.1 - 2.3e-221 736.2 0.4 3.7e-221 735.6 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 GAP90105.1 - 5e-24 85.0 0.0 1.9e-23 83.1 0.0 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 GAP90105.1 - 4.8e-14 51.9 0.0 1.3e-05 24.1 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 GAP90105.1 - 0.04 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Mo25 PF08569.11 GAP90108.1 - 1.9e-119 398.9 0.0 2.1e-119 398.7 0.0 1.0 1 0 0 1 1 1 1 Mo25-like adh_short PF00106.25 GAP90109.1 - 1.4e-35 122.5 0.1 1.8e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP90109.1 - 2.8e-24 86.0 0.0 4e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP90109.1 - 5.5e-06 26.4 1.0 2.5e-05 24.2 0.6 2.2 2 1 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 GAP90109.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SWIB PF02201.18 GAP90110.1 - 1.8e-21 75.8 0.0 3.8e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain TFIIA PF03153.13 GAP90110.1 - 1.4e-06 28.6 23.3 2.1e-06 28.0 23.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 GAP90110.1 - 0.013 15.6 2.5 0.22 11.7 1.8 2.3 2 0 0 2 2 2 0 DDHD domain eIF-3_zeta PF05091.12 GAP90110.1 - 0.22 10.5 8.9 0.31 10.0 8.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4770 PF15994.5 GAP90110.1 - 0.25 11.6 14.2 0.53 10.5 14.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SpoIIP PF07454.11 GAP90110.1 - 0.28 10.6 5.2 0.46 9.9 5.2 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4407 PF14362.6 GAP90110.1 - 2 7.7 7.8 3.2 7.0 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SARAF PF06682.12 GAP90110.1 - 2.3 7.8 10.7 4.1 6.9 10.7 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Presenilin PF01080.17 GAP90110.1 - 2.7 6.7 9.5 3.8 6.2 9.5 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 GAP90110.1 - 4.1 5.5 21.9 5.7 5.1 21.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EIIBC-GUT_N PF03612.14 GAP90110.1 - 4.8 6.9 6.6 9.6 5.9 6.6 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ndc1_Nup PF09531.10 GAP90110.1 - 5.2 5.6 11.1 7 5.2 11.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 GAP90110.1 - 6.1 6.8 5.3 11 6.0 5.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 GAP90110.1 - 8 6.3 16.7 3.7 7.5 14.1 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 GAP90110.1 - 9.5 6.2 14.8 20 5.2 13.6 2.0 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Pkinase PF00069.25 GAP90111.1 - 1.4e-68 231.2 0.0 9.4e-68 228.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP90111.1 - 3.1e-36 125.0 0.0 1e-24 87.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAP90111.1 - 3.7e-05 23.2 0.9 0.025 13.9 0.1 3.1 2 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 GAP90111.1 - 0.00017 20.7 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 GAP90111.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP90111.1 - 0.0067 16.4 0.1 0.023 14.6 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 GAP90111.1 - 0.1 12.2 0.2 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ANAPC_CDC26 PF10471.9 GAP90112.1 - 0.00034 21.4 0.4 0.00034 21.4 0.4 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 IFT43 PF15305.6 GAP90113.1 - 0.028 14.6 0.4 0.068 13.3 0.4 1.7 1 0 0 1 1 1 0 Intraflagellar transport protein 43 TORC_N PF12884.7 GAP90113.1 - 0.086 13.6 0.2 0.24 12.2 0.2 1.8 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus GEN1_C PF18380.1 GAP90115.1 - 1.5e-28 99.8 0.0 1.5e-28 99.8 0.0 2.4 3 1 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 GAP90115.1 - 2e-25 89.0 0.0 4e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 GAP90115.1 - 7.2e-08 32.8 0.0 1.5e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.19 GAP90116.1 - 4.7e-21 74.9 0.0 9.6e-20 70.6 0.0 2.4 1 1 0 1 1 1 1 Actin DUF3630 PF12305.8 GAP90116.1 - 0.22 11.6 0.3 0.85 9.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3630) MreB_Mbl PF06723.13 GAP90116.1 - 0.27 10.0 0.0 1.4 7.6 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein HET PF06985.11 GAP90117.1 - 6.5e-37 127.1 6.3 6.5e-37 127.1 6.3 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) tRNA-synt_2b PF00587.25 GAP90117.1 - 1.9e-19 70.3 0.0 4.5e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TPR_10 PF13374.6 GAP90117.1 - 5.1e-13 48.4 1.1 2.1e-07 30.6 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAP90117.1 - 1.2e-11 44.7 1.4 3.7e-07 30.3 0.1 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat Seryl_tRNA_N PF02403.22 GAP90117.1 - 5.8e-11 42.6 6.9 9.2e-06 25.9 0.2 2.8 3 0 0 3 3 3 2 Seryl-tRNA synthetase N-terminal domain Nucleo_P87 PF07267.11 GAP90117.1 - 0.047 12.6 3.2 0.082 11.8 3.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4887 PF16228.5 GAP90117.1 - 0.05 13.8 10.4 0.094 12.9 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Vps4_C PF09336.10 GAP90118.1 - 0.0049 16.9 2.9 8.8 6.4 0.0 5.6 5 0 0 5 5 5 1 Vps4 C terminal oligomerisation domain DUF4400 PF14348.6 GAP90118.1 - 0.025 14.1 1.5 0.13 11.7 1.5 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Fe_dep_repress PF01325.19 GAP90118.1 - 0.085 13.1 0.3 0.26 11.5 0.3 1.8 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Tup_N PF08581.10 GAP90118.1 - 0.16 12.3 14.5 0.26 11.6 1.2 6.9 4 1 1 5 5 5 0 Tup N-terminal PAP_fibrillin PF04755.12 GAP90118.1 - 1.9 8.4 5.3 6.4 6.7 0.1 3.6 3 0 0 3 3 3 0 PAP_fibrillin Mito_carr PF00153.27 GAP90119.1 - 3.3e-29 100.7 0.2 8.7e-15 54.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpc82 PF05645.13 GAP90120.1 - 4.4e-38 131.5 0.1 3.2e-37 128.7 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 GAP90120.1 - 1e-18 67.2 0.8 3.7e-17 62.2 0.2 3.3 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 GAP90120.1 - 1.1e-06 28.4 0.8 0.00051 19.9 0.0 3.1 3 0 0 3 3 3 2 TFIIE alpha subunit ATP-synt_Eps PF04627.13 GAP90121.1 - 9.6e-22 76.7 0.6 3.6e-21 74.9 0.6 2.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.20 GAP90121.1 - 3.5e-16 59.5 0.1 7.3e-16 58.5 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 GAP90121.1 - 2.4e-12 47.2 0.0 6.2e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Mak10 PF04112.13 GAP90122.1 - 4.5e-56 189.0 0.1 8e-56 188.1 0.1 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Mito_carr PF00153.27 GAP90123.1 - 2.5e-49 165.2 3.5 3.2e-15 55.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Abp2 PF09441.10 GAP90124.1 - 6.2e-88 293.3 0.0 1.2e-87 292.4 0.0 1.4 1 0 0 1 1 1 1 ARS binding protein 2 Sugar_tr PF00083.24 GAP90125.1 - 7.4e-92 308.6 20.7 9.1e-92 308.3 20.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP90125.1 - 3.7e-14 52.4 50.1 1.9e-09 36.9 34.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GAF_3 PF13492.6 GAP90126.1 - 0.022 15.1 0.1 0.23 11.8 0.0 2.3 1 1 1 2 2 2 0 GAF domain PFL-like PF02901.15 GAP90126.1 - 0.077 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyruvate formate lyase-like RasGAP PF00616.19 GAP90127.1 - 6.1e-33 114.3 1.2 2.9e-21 76.1 0.1 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 GAP90127.1 - 0.0012 19.1 0.1 0.0036 17.5 0.1 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain XRN_M PF17846.1 GAP90128.1 - 2.4e-140 468.4 0.0 7e-140 466.9 0.0 1.7 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 GAP90128.1 - 7.8e-99 330.0 0.0 1.3e-98 329.3 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_2 PF13696.6 GAP90128.1 - 0.25 11.2 3.2 0.6 10.0 3.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_head PF04869.14 GAP90129.1 - 1e-113 379.6 0.0 2.2e-113 378.5 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 GAP90129.1 - 4.6e-19 69.0 25.5 4.6e-19 69.0 25.5 5.4 4 1 1 5 5 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Methyltransf_25 PF13649.6 GAP90129.1 - 1.4e-09 38.5 1.3 1.1e-08 35.7 0.1 3.2 3 0 0 3 3 2 1 Methyltransferase domain PrmA PF06325.13 GAP90129.1 - 4e-08 33.0 0.1 4e-08 33.0 0.1 2.0 2 0 0 2 2 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 GAP90129.1 - 5.8e-07 30.1 1.2 3.8e-06 27.4 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP90129.1 - 1.8e-06 27.9 0.0 2.9e-05 24.0 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP90129.1 - 0.00017 21.4 2.1 0.00021 21.1 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAP90129.1 - 0.00051 20.0 0.1 0.00051 20.0 0.1 2.5 4 0 0 4 4 4 1 Methyltransferase domain MTS PF05175.14 GAP90129.1 - 0.00076 19.1 0.0 0.0021 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 GAP90129.1 - 0.0011 18.3 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 GAP90129.1 - 0.0092 14.9 0.0 0.028 13.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 GAP90129.1 - 0.019 15.1 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 GAP90129.1 - 0.021 14.5 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 GAP90129.1 - 0.026 13.8 0.0 0.078 12.3 0.0 1.8 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_12 PF08242.12 GAP90129.1 - 0.032 15.0 3.4 0.05 14.4 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain PCMT PF01135.19 GAP90129.1 - 0.038 13.7 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 GAP90129.1 - 0.48 10.4 0.0 0.48 10.4 0.0 4.0 3 1 0 3 3 2 0 Methyltransferase domain FAM196 PF15265.6 GAP90129.1 - 3.9 6.9 29.1 0.099 12.1 22.3 1.6 2 0 0 2 2 2 0 FAM196 family Methyltransf_24 PF13578.6 GAP90129.1 - 7.5 7.6 8.6 1.5 9.9 0.0 3.4 2 1 0 2 2 1 0 Methyltransferase domain MS_channel PF00924.18 GAP90130.1 - 4.9e-18 65.4 1.7 8e-18 64.7 1.7 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 GAP90130.1 - 0.00068 19.0 0.2 0.0014 18.0 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 GAP90130.1 - 0.0026 17.2 0.5 0.0061 16.0 0.5 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 GAP90130.1 - 0.0069 16.8 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 GAP90130.1 - 0.012 15.5 0.1 0.035 14.0 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 GAP90130.1 - 0.18 11.7 0.3 0.39 10.6 0.3 1.5 1 0 0 1 1 1 0 EF-hand domain pair NUDIX_4 PF14815.6 GAP90131.1 - 3.1e-18 65.8 0.1 1.1e-17 64.0 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain HhH-GPD PF00730.25 GAP90131.1 - 2.1e-17 63.5 0.0 4.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 GAP90131.1 - 9.1e-06 25.3 0.1 2.3e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif PNGaseA PF12222.8 GAP90132.1 - 7.3e-137 456.8 0.1 9.7e-137 456.4 0.1 1.0 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A HAD_2 PF13419.6 GAP90134.1 - 6.4e-19 68.7 0.0 1.4e-18 67.6 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP90134.1 - 2.8e-07 31.0 0.0 1.9e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP90134.1 - 2.6e-06 27.4 0.0 1e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Glyco_hydro_26 PF02156.15 GAP90135.1 - 1.4e-87 294.0 4.4 1.8e-87 293.7 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 GAP90135.1 - 3.9e-32 111.1 3.2 7.2e-32 110.2 3.2 1.5 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) Harakiri PF15196.6 GAP90135.1 - 0.11 13.0 0.2 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 Activator of apoptosis harakiri Phage_lysis PF03245.13 GAP90135.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein p450 PF00067.22 GAP90136.1 - 1.4e-53 182.3 0.0 1.7e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF829 PF05705.14 GAP90137.1 - 8.8e-46 156.7 0.7 1.1e-45 156.4 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) 6PF2K PF01591.18 GAP90138.1 - 6.2e-78 261.1 0.0 8.3e-78 260.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 GAP90138.1 - 6e-37 127.2 0.0 1.1e-36 126.4 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 GAP90138.1 - 1.1e-06 28.8 0.0 2.1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 GAP90138.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Sigma70_ner PF04546.13 GAP90138.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region HET PF06985.11 GAP90139.1 - 5.2e-22 78.8 0.0 1e-21 77.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 GAP90141.1 - 1.8e-76 257.7 0.0 2.2e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAP90141.1 - 3.7e-36 124.7 0.0 1.4e-35 122.8 0.0 1.9 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 GAP90141.1 - 3.5e-05 23.2 0.0 0.0047 16.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP90141.1 - 0.00014 22.4 0.0 0.0022 18.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP90141.1 - 0.0021 18.3 0.0 0.009 16.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 GAP90141.1 - 0.0092 16.5 0.0 0.05 14.1 0.0 2.1 2 0 0 2 2 2 1 XdhC Rossmann domain DAO PF01266.24 GAP90141.1 - 0.023 14.3 0.3 1.2 8.6 0.1 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 GAP90141.1 - 0.036 12.8 0.0 0.087 11.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 GAP90141.1 - 0.062 12.9 0.6 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4185 PF13810.6 GAP90142.1 - 1.2e-09 37.8 2.8 1.6e-09 37.4 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Peptidase_C48 PF02902.19 GAP90143.1 - 5e-15 55.9 1.0 9.4e-15 55.0 1.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Amelogenin PF02948.15 GAP90143.1 - 0.022 15.4 6.7 0.03 15.0 3.8 2.3 2 0 0 2 2 2 0 Amelogenin zf-RING_2 PF13639.6 GAP90144.1 - 2e-06 28.0 7.0 3.8e-06 27.1 7.0 1.5 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAP90144.1 - 4e-06 27.0 3.2 5.6e-06 26.6 3.2 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAP90144.1 - 0.00016 21.6 4.9 0.00024 21.0 4.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAP90144.1 - 0.00019 21.2 4.3 0.00024 20.9 1.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP90144.1 - 0.00056 19.7 5.2 0.00078 19.3 5.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF983 PF06170.12 GAP90144.1 - 0.0017 18.7 2.7 0.047 14.1 0.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF983) Prok-RING_4 PF14447.6 GAP90144.1 - 0.0028 17.5 5.6 0.045 13.6 2.8 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAP90144.1 - 0.0033 17.2 7.3 0.014 15.2 7.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP90144.1 - 0.0034 17.4 4.5 0.0034 17.4 4.5 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 GAP90144.1 - 0.049 13.5 0.6 0.067 13.0 0.6 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 GAP90144.1 - 0.068 12.9 1.9 0.068 12.9 1.9 2.1 3 0 0 3 3 3 0 RING-like zinc finger HypA PF01155.19 GAP90144.1 - 0.069 13.2 0.5 0.26 11.3 0.5 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Pellino PF04710.14 GAP90144.1 - 0.15 10.7 0.5 0.16 10.6 0.5 1.1 1 0 0 1 1 1 0 Pellino zf-ANAPC11 PF12861.7 GAP90144.1 - 0.18 11.9 2.7 0.25 11.4 2.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Lar_restr_allev PF14354.6 GAP90144.1 - 3.6 8.0 6.9 6.8 7.1 5.4 2.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar Mito_carr PF00153.27 GAP90145.1 - 1.5e-68 226.8 6.2 1.2e-25 89.3 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 GAP90145.1 - 3.8e-21 75.3 4.1 4.2e-12 46.3 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 GAP90145.1 - 4.2e-20 69.9 6.1 2.2e-06 27.1 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 GAP90145.1 - 2.6e-19 67.3 4.0 8.1e-05 21.9 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 GAP90145.1 - 1.4e-17 62.3 3.9 0.00011 21.5 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 GAP90145.1 - 6.8e-10 38.6 1.9 0.0014 18.4 0.1 3.4 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 GAP90145.1 - 1.2e-07 32.1 0.4 0.0015 18.8 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAP90145.1 - 0.0091 15.9 2.3 1.6 8.7 0.0 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Serine_protease PF18405.1 GAP90145.1 - 0.017 14.3 2.0 4.2 6.5 0.0 3.4 3 1 0 3 3 3 0 Gammaproteobacterial serine protease EF-hand_14 PF17959.1 GAP90145.1 - 0.027 14.8 0.6 0.11 12.8 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 GAP90145.1 - 0.44 10.5 1.9 1.1 9.1 0.2 2.5 2 1 1 3 3 3 0 EF hand DUF515 PF04415.12 GAP90145.1 - 1.4 7.2 6.7 2.4 6.5 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Cyclin_N PF00134.23 GAP90146.1 - 4.3e-12 45.9 2.8 5.8e-12 45.5 0.3 2.4 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 GAP90146.1 - 0.0024 18.2 0.3 0.01 16.2 0.3 2.1 1 0 0 1 1 1 1 Cyclin C-terminal domain Herpes_LMP2 PF07415.11 GAP90146.1 - 0.045 12.5 0.1 0.061 12.1 0.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein TFIIB PF00382.19 GAP90146.1 - 0.064 13.3 0.3 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DUF4298 PF14131.6 GAP90146.1 - 0.36 10.8 2.8 0.3 11.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) ACC_epsilon PF13822.6 GAP90146.1 - 7.7 7.3 10.5 2.1 9.1 6.4 2.1 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Ubie_methyltran PF01209.18 GAP90147.1 - 2.3e-05 23.8 0.0 0.0012 18.3 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAP90147.1 - 0.00028 20.8 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP90147.1 - 0.0031 18.1 0.0 0.0093 16.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP90147.1 - 0.023 14.5 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAP90147.1 - 0.032 15.0 0.0 0.075 13.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain G-7-MTase PF12803.7 GAP90147.1 - 0.098 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Couple_hipA PF13657.6 GAP90147.1 - 0.15 12.8 0.0 0.2 12.3 0.0 1.2 1 0 0 1 1 1 0 HipA N-terminal domain DUF4452 PF14618.6 GAP90148.1 - 2.3e-78 261.9 14.9 3.2e-78 261.4 14.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) KH_1 PF00013.29 GAP90149.1 - 1.7e-47 159.1 14.6 4.3e-16 58.5 1.7 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 GAP90149.1 - 4.4e-12 45.7 3.5 0.01 15.6 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 GAP90149.1 - 4.4e-09 36.1 4.4 0.079 12.8 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 GAP90149.1 - 0.00085 19.4 4.1 5.8 7.1 0.0 3.3 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 GAP90149.1 - 0.0057 16.6 0.0 6 6.9 0.0 3.0 3 0 0 3 3 3 2 KH-like RNA-binding domain Meth_synt_2 PF01717.18 GAP90150.1 - 3.6e-08 33.0 0.0 2.2e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 GAP90150.1 - 0.0036 16.9 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain SNARE PF05739.19 GAP90151.1 - 2.9e-08 33.6 4.4 5.4e-08 32.7 4.4 1.5 1 0 0 1 1 1 1 SNARE domain Snapin_Pallidin PF14712.6 GAP90151.1 - 0.083 13.3 2.0 0.23 11.9 0.7 2.2 2 1 0 2 2 2 0 Snapin/Pallidin Use1 PF09753.9 GAP90151.1 - 0.099 12.4 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Membrane fusion protein Use1 Fusion_gly PF00523.18 GAP90151.1 - 0.11 10.8 0.5 0.13 10.5 0.5 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Med9 PF07544.13 GAP90151.1 - 0.23 11.6 6.5 3.5 7.8 0.1 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 CorA PF01544.18 GAP90151.1 - 1.4 8.2 5.1 2.6 7.3 0.0 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein GIT_CC PF16559.5 GAP90152.1 - 0.0048 16.7 5.5 0.74 9.7 0.1 3.7 2 1 2 4 4 4 2 GIT coiled-coil Rho guanine nucleotide exchange factor Glyco_hydro_42M PF08532.10 GAP90152.1 - 0.073 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain DUF5448 PF17526.2 GAP90152.1 - 0.085 13.0 1.3 0.36 11.0 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5448) adh_short PF00106.25 GAP90153.1 - 9.5e-06 25.2 0.0 0.00021 20.8 0.0 2.3 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAP90153.1 - 0.011 15.6 0.0 0.017 15.1 0.0 1.3 2 0 0 2 2 2 0 KR domain Epimerase PF01370.21 GAP90153.1 - 0.076 12.5 0.0 1.3 8.4 0.0 2.0 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family PMSI1 PF15322.6 GAP90153.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Baculo_PEP_C PF04513.12 GAP90154.1 - 0.038 14.0 8.8 0.35 10.9 0.4 3.8 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus HemX PF04375.14 GAP90154.1 - 0.099 11.9 0.4 3.3 6.9 0.0 2.4 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase MT0933_antitox PF14013.6 GAP90154.1 - 1.2 9.5 3.8 16 5.9 3.7 2.7 1 1 0 1 1 1 0 MT0933-like antitoxin protein DUF948 PF06103.11 GAP90154.1 - 3.9 7.8 10.5 11 6.4 0.0 5.0 6 0 0 6 6 6 0 Bacterial protein of unknown function (DUF948) Pex14_N PF04695.13 GAP90155.1 - 2.8e-29 102.8 0.4 2.8e-29 102.8 0.4 1.6 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region AIP3 PF03915.13 GAP90155.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 PAPA-1 PF04795.12 GAP90156.1 - 1.4e-29 102.7 3.2 1.4e-29 102.7 3.2 4.0 4 1 0 4 4 4 1 PAPA-1-like conserved region DUF4050 PF13259.6 GAP90159.1 - 1.1e-53 182.3 0.0 1.1e-53 182.3 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) p450 PF00067.22 GAP90161.1 - 1e-48 166.3 0.0 1.7e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 GAP90162.1 - 1.6e-21 76.5 1.4 3e-21 75.6 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP90162.1 - 3.6e-09 36.6 1.2 3.6e-09 36.6 1.2 2.0 2 0 0 2 2 2 1 Berberine and berberine like Abhydrolase_1 PF00561.20 GAP90163.1 - 1.9e-10 40.8 0.0 6.4e-08 32.5 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP90163.1 - 3.7e-10 40.8 1.3 4.3e-10 40.6 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP90163.1 - 7.7e-09 35.2 0.0 9.9e-08 31.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 GAP90163.1 - 1.9e-06 27.9 0.0 4.1e-06 26.9 0.0 1.5 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 GAP90163.1 - 2.8e-06 26.2 0.0 1.7e-05 23.7 0.0 2.0 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 GAP90163.1 - 4.1e-06 26.6 0.0 5.7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 GAP90163.1 - 1.6e-05 24.5 0.0 6.1e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 GAP90163.1 - 0.00019 21.0 0.0 0.0015 18.1 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF1100 PF06500.11 GAP90163.1 - 0.0021 16.9 0.0 0.0085 14.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.20 GAP90163.1 - 0.098 12.3 0.0 0.39 10.3 0.0 2.0 1 1 0 1 1 1 0 Putative esterase ketoacyl-synt PF00109.26 GAP90164.1 - 1.9e-65 221.0 0.0 4.2e-65 219.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP90164.1 - 3.3e-54 183.5 0.2 4.6e-53 179.8 0.1 2.7 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 GAP90164.1 - 1.2e-53 182.4 0.0 1.9e-53 181.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP90164.1 - 4.4e-46 157.9 0.0 7e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP90164.1 - 4.4e-31 107.4 0.6 1e-30 106.2 0.3 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAP90164.1 - 1.1e-21 77.4 0.0 2.2e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 GAP90164.1 - 1.2e-19 71.7 0.0 5.7e-19 69.5 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAP90164.1 - 2.5e-18 66.3 0.0 1.5e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 GAP90164.1 - 1.8e-09 37.4 0.7 1.1e-07 31.5 0.2 3.6 4 0 0 4 4 4 1 short chain dehydrogenase ADH_N PF08240.12 GAP90164.1 - 4.1e-06 26.6 0.8 9.3e-06 25.5 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 GAP90164.1 - 7.5e-05 22.6 0.2 0.32 10.7 0.0 2.4 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 GAP90164.1 - 8.1e-05 22.9 0.0 0.0002 21.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 GAP90164.1 - 0.0015 18.1 0.2 0.0067 16.0 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 GAP90164.1 - 0.017 14.9 0.1 0.082 12.8 0.1 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Isy1 PF06246.12 GAP90165.1 - 4.7e-88 295.0 0.0 5.3e-88 294.9 0.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 GAP90165.1 - 0.018 15.1 0.5 0.04 14.0 0.0 1.8 2 0 0 2 2 2 0 YolD-like protein Metallophos PF00149.28 GAP90166.1 - 1.3e-10 42.1 1.6 3.1e-10 40.9 1.6 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Amidase PF01425.21 GAP90167.1 - 7.1e-99 331.8 0.0 1.1e-98 331.2 0.0 1.2 1 0 0 1 1 1 1 Amidase Big_3_5 PF16640.5 GAP90167.1 - 0.038 14.2 0.4 0.11 12.6 0.4 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) PRP38 PF03371.15 GAP90168.1 - 1.4e-22 80.4 0.1 1.7e-22 80.1 0.1 1.1 1 0 0 1 1 1 1 PRP38 family CDC45 PF02724.14 GAP90168.1 - 0.047 12.0 6.0 0.045 12.1 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DDOST_48kD PF03345.14 GAP90170.1 - 1.5e-159 531.3 0.0 1.7e-159 531.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NADHdh_A3 PF14987.6 GAP90171.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Beach PF02138.18 GAP90172.1 - 5.9e-119 396.5 0.0 8.8e-119 395.9 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 GAP90172.1 - 6.7e-11 42.2 0.3 2.1e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 GAP90172.1 - 2.1e-10 41.0 0.0 4.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 GAP90172.1 - 0.024 15.5 8.0 2.6 9.0 0.4 5.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Peptidase_S8 PF00082.22 GAP90173.1 - 2.1e-31 109.3 8.3 3.4e-31 108.6 8.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 GAP90173.1 - 2.2e-20 73.1 0.2 5.2e-20 71.9 0.2 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Phasin PF05597.11 GAP90173.1 - 0.03 14.3 0.3 0.052 13.6 0.3 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) eIF-3_zeta PF05091.12 GAP90174.1 - 0.0022 17.1 13.1 0.0058 15.7 13.1 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 GAP90174.1 - 0.0095 15.4 8.5 0.026 14.0 8.5 1.7 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 GAP90174.1 - 0.016 15.3 7.2 0.1 12.7 7.2 2.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF4407 PF14362.6 GAP90174.1 - 0.056 12.8 8.5 0.16 11.3 8.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MecA PF05389.12 GAP90174.1 - 0.089 12.4 4.9 0.2 11.2 4.9 1.6 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Cellulose_synt PF03552.14 GAP90174.1 - 0.15 10.5 0.2 0.24 9.9 0.2 1.2 1 0 0 1 1 1 0 Cellulose synthase CobT PF06213.12 GAP90174.1 - 0.15 11.4 18.6 0.51 9.7 18.6 1.8 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AAA_23 PF13476.6 GAP90174.1 - 0.44 11.0 12.1 0.049 14.1 7.5 1.8 2 0 0 2 2 2 0 AAA domain RPA43_OB PF17875.1 GAP90174.1 - 1.4 9.5 8.7 3 8.5 4.9 2.8 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF4770 PF15994.5 GAP90174.1 - 1.5 9.1 16.5 0.49 10.6 11.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF4746 PF15928.5 GAP90174.1 - 2.1 7.7 11.1 4.9 6.5 6.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 GAP90174.1 - 2.4 7.9 19.0 0.059 13.2 8.3 3.0 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 Peroxin-13_N PF04088.13 GAP90174.1 - 2.4 8.4 6.6 9.8 6.5 6.6 2.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region PTPRCAP PF15713.5 GAP90174.1 - 2.7 8.3 17.8 1.1 9.6 13.8 2.4 2 0 0 2 2 1 0 Protein tyrosine phosphatase receptor type C-associated NARP1 PF12569.8 GAP90174.1 - 4.6 6.0 11.7 7.8 5.3 11.7 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Connexin PF00029.19 GAP90174.1 - 5.4 6.7 9.3 16 5.1 9.3 1.7 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 GAP90174.1 - 6.1 5.6 5.4 13 4.6 5.4 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Folate_carrier PF01770.18 GAP90174.1 - 7.1 5.2 5.6 12 4.5 5.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier Orf78 PF06024.12 GAP90174.1 - 9.5 6.6 8.3 43 4.5 8.3 2.1 1 0 0 1 1 1 0 Orf78 (ac78) TMEM51 PF15345.6 GAP90174.1 - 9.6 6.0 20.7 0.4 10.5 8.6 4.0 3 0 0 3 3 3 0 Transmembrane protein 51 ATP-synt_C PF00137.21 GAP90177.1 - 1.8e-27 95.5 34.9 1.9e-17 63.4 12.7 2.9 3 0 0 3 3 3 2 ATP synthase subunit C SAYSvFN PF10260.9 GAP90177.1 - 0.046 13.6 2.6 0.57 10.1 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) ELP6 PF09807.9 GAP90177.1 - 0.21 11.0 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Elongation complex protein 6 CNH PF00780.22 GAP90178.1 - 1.6e-76 257.5 0.0 6.1e-76 255.6 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 GAP90178.1 - 4.4e-40 136.9 1.9 4.5e-40 136.9 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.20 GAP90178.1 - 2.2e-35 122.5 0.3 4.8e-35 121.4 0.1 1.8 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.21 GAP90178.1 - 2.1e-15 56.5 0.0 3.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF818 PF05677.12 GAP90178.1 - 0.059 12.3 0.1 0.098 11.6 0.1 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF4336 PF14234.6 GAP90179.1 - 2.6e-13 49.9 0.1 5.8e-10 38.9 0.1 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) GAS PF13851.6 GAP90180.1 - 0.00084 18.8 9.9 0.00084 18.8 9.9 5.0 2 2 2 4 4 3 2 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 GAP90180.1 - 0.0024 17.0 9.0 0.0024 17.0 9.0 4.1 3 1 1 4 4 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 GAP90180.1 - 0.0032 17.5 12.7 0.0032 17.5 12.7 6.3 3 3 3 6 6 5 2 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 GAP90180.1 - 0.0062 16.2 12.9 0.0062 16.2 12.9 4.8 3 2 1 4 4 4 1 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 GAP90180.1 - 0.014 15.4 1.5 0.014 15.4 1.5 5.4 4 1 3 7 7 6 0 Protein of unknown function (DUF1664) HSBP1 PF06825.12 GAP90180.1 - 0.021 14.7 3.6 0.4 10.6 0.0 3.9 5 0 0 5 5 4 0 Heat shock factor binding protein 1 DUF5082 PF16888.5 GAP90180.1 - 0.024 14.9 1.0 0.024 14.9 1.0 6.2 3 2 2 6 6 6 0 Domain of unknown function (DUF5082) zf-ISL3 PF14690.6 GAP90180.1 - 0.11 13.1 0.0 0.33 11.7 0.0 1.8 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Baculo_PEP_C PF04513.12 GAP90180.1 - 0.24 11.4 9.0 6.7 6.8 1.2 4.5 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 GAP90180.1 - 0.25 11.8 5.1 1.2 9.6 0.3 3.6 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TSC22 PF01166.18 GAP90180.1 - 1.1 9.6 0.0 0.29 11.5 1.3 5.6 6 1 1 7 7 6 0 TSC-22/dip/bun family Snapin_Pallidin PF14712.6 GAP90180.1 - 1.5 9.3 40.7 0.2 12.1 2.9 6.9 4 3 4 8 8 8 0 Snapin/Pallidin Fib_alpha PF08702.10 GAP90180.1 - 1.8 8.8 36.3 1.4 9.1 2.6 5.2 2 2 5 7 7 7 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.11 GAP90180.1 - 5.4 6.8 25.4 6.1 6.6 1.7 4.5 3 2 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.9 GAP90180.1 - 8.3 6.4 61.4 0.021 14.9 7.1 4.8 3 1 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nse4_C PF08743.10 GAP90182.1 - 2.1e-35 120.8 0.0 5.1e-35 119.6 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 GAP90182.1 - 5.7e-16 58.4 0.0 5.7e-16 58.4 0.0 2.6 3 0 0 3 3 3 1 Binding domain of Nse4/EID3 to Nse3-MAGE PI3Ka PF00613.20 GAP90183.1 - 2.2e-57 193.4 1.1 3.3e-57 192.9 1.1 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 GAP90183.1 - 4.7e-45 154.4 0.0 2e-30 106.4 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 GAP90183.1 - 7.2e-34 116.7 0.0 1.3e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 GAP90183.1 - 0.0029 17.9 0.0 0.0087 16.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain WD40 PF00400.32 GAP90185.1 - 2.8e-21 75.4 17.3 1.6e-06 28.7 0.4 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP90185.1 - 9e-05 22.7 0.1 0.021 15.1 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 GAP90185.1 - 0.0024 16.5 0.6 0.87 8.0 0.0 3.5 4 0 0 4 4 4 1 Cytochrome D1 heme domain PD40 PF07676.12 GAP90185.1 - 0.011 15.6 0.5 0.09 12.8 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SecE PF00584.20 GAP90186.1 - 2.1e-15 56.4 0.0 2.4e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_1 PF00076.22 GAP90187.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-binding PF00249.31 GAP90189.1 - 6.7e-17 61.4 0.4 6.7e-09 35.8 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP90189.1 - 1.4e-10 41.3 0.0 0.00013 22.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 GAP90189.1 - 4.1e-06 26.8 0.1 0.052 13.6 0.0 2.4 2 0 0 2 2 2 2 SLIDE CHDCT2 PF08074.11 GAP90189.1 - 0.01 16.0 0.0 0.03 14.5 0.0 1.7 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain SANT_DAMP1_like PF16282.5 GAP90189.1 - 0.017 15.3 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 P22_Cro PF14549.6 GAP90189.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro Ribosomal_L27A PF00828.19 GAP90190.1 - 6.2e-12 46.3 0.0 6.6e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_S4e PF00900.20 GAP90191.1 - 1.4e-36 124.2 0.2 3.4e-36 123.0 0.2 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 GAP90191.1 - 1.4e-24 85.4 0.1 2.4e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 GAP90191.1 - 1.2e-17 63.7 6.1 2.1e-17 62.9 6.1 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 GAP90191.1 - 2.9e-06 26.9 0.0 5.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 GAP90191.1 - 6.5e-05 22.7 1.5 6.5e-05 22.7 1.5 3.2 4 0 0 4 4 4 1 KOW motif FAD-oxidase_C PF02913.19 GAP90192.1 - 4.7e-61 206.6 0.0 7.5e-61 205.9 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 GAP90192.1 - 2.8e-33 114.6 0.0 4.9e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain RdRP PF05183.12 GAP90193.1 - 9.1e-184 612.4 0.0 1.2e-183 612.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 GAP90193.1 - 0.0068 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAC PF01849.18 GAP90194.1 - 6.8e-23 80.4 0.1 1e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 NAC domain A_deamin PF02137.18 GAP90195.1 - 4.9e-23 82.1 0.0 9.2e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Acylphosphatase PF00708.18 GAP90195.1 - 0.049 14.0 0.0 0.094 13.1 0.0 1.4 1 0 0 1 1 1 0 Acylphosphatase Ribosomal_L24e PF01246.20 GAP90196.1 - 6.7e-28 96.7 0.2 1.5e-27 95.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Mobilization_B PF17511.2 GAP90196.1 - 1 9.7 6.7 10 6.5 1.7 2.1 1 1 1 2 2 2 0 Mobilization protein B LMBR1 PF04791.16 GAP90196.1 - 1.6 7.6 2.3 1.7 7.4 2.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Redoxin PF08534.10 GAP90197.1 - 1.5e-39 135.1 0.0 1.6e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 GAP90197.1 - 7.1e-09 35.6 0.0 9.5e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family CHAT PF12770.7 GAP90198.1 - 1.3e-07 31.4 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 CHAT domain Peptidase_C50 PF03568.17 GAP90198.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.4 2 0 0 2 2 2 0 Peptidase family C50 DUF1348 PF07080.11 GAP90199.1 - 4.7e-60 201.2 6.4 7.7e-60 200.5 6.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 GAP90199.1 - 1.1e-07 32.4 3.1 1.5e-07 31.9 2.9 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 GAP90199.1 - 0.00023 21.5 2.1 0.00033 21.0 2.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) RGS PF00615.19 GAP90200.1 - 0.0056 16.9 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain Fumble PF03630.14 GAP90201.1 - 6.8e-145 482.4 0.1 8.2e-145 482.1 0.1 1.1 1 0 0 1 1 1 1 Fumble OAR PF03826.17 GAP90203.1 - 0.015 15.2 1.3 0.04 13.7 1.3 1.7 1 0 0 1 1 1 0 OAR domain Arm-DNA-bind_3 PF13356.6 GAP90203.1 - 0.087 13.2 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Arm DNA-binding domain PDEase_I_N PF08499.12 GAP90203.1 - 0.19 11.6 1.1 0.63 9.9 0.1 2.0 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal PUFD PF16553.5 GAP90204.1 - 0.1 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain 2OG-FeII_Oxy_3 PF13640.6 GAP90205.1 - 7e-10 39.7 0.0 1.3e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NACHT PF05729.12 GAP90207.1 - 5e-09 36.3 0.1 2e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GAP90207.1 - 9.4e-07 29.4 0.1 2.3e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 GAP90207.1 - 0.00059 20.4 0.0 0.0015 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 GAP90207.1 - 0.0069 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 GAP90207.1 - 0.007 16.6 0.0 0.021 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAP90207.1 - 0.012 16.0 0.0 0.036 14.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 GAP90207.1 - 0.066 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 GAP90207.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAP90207.1 - 0.076 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 GAP90207.1 - 0.093 13.1 0.1 0.48 10.8 0.1 2.1 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 GAP90207.1 - 0.16 12.1 0.0 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 GAP90207.1 - 0.2 11.4 0.1 1.7 8.3 0.1 2.1 2 0 0 2 2 2 0 Cytidylate kinase KAP_NTPase PF07693.14 GAP90207.1 - 0.4 9.9 3.4 0.64 9.2 0.8 2.1 1 1 1 2 2 2 0 KAP family P-loop domain Tex_YqgF PF16921.5 GAP90208.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Tex protein YqgF-like domain Glyco_hydro2_C5 PF18565.1 GAP90209.1 - 8e-32 109.2 0.1 1.8e-31 108.0 0.0 1.6 2 0 0 2 2 2 1 Glycoside hydrolase family 2 C-terminal domain 5 DUF4982 PF16355.5 GAP90209.1 - 5e-24 84.0 0.2 1.3e-23 82.7 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4982) Glyco_hydro_2_C PF02836.17 GAP90209.1 - 7.3e-21 74.5 0.1 2.5e-19 69.5 0.0 2.3 1 1 1 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 GAP90209.1 - 1.1e-19 71.0 0.0 7.5e-19 68.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 GAP90209.1 - 7.8e-17 61.9 0.1 2.1e-16 60.5 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Invasin_D3 PF09134.10 GAP90209.1 - 5e-05 23.5 3.8 0.001 19.3 0.4 3.1 3 0 0 3 3 3 1 Invasin, domain 3 BetaGal_dom4_5 PF13364.6 GAP90209.1 - 0.00025 21.6 1.0 0.0019 18.8 0.0 2.9 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain PGM_PMM_IV PF00408.20 GAP90209.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Fungal_trans PF04082.18 GAP90210.1 - 3e-14 52.7 0.0 4.8e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP90210.1 - 5.6e-09 36.0 12.4 1e-08 35.2 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 GAP90211.1 - 3.2e-12 46.7 0.0 4.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding IDO PF01231.18 GAP90214.1 - 9.5e-151 502.4 0.0 1.1e-150 502.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Fungal_trans PF04082.18 GAP90215.1 - 1e-11 44.4 0.0 1.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP90215.1 - 9.8e-08 32.0 12.5 1.7e-07 31.2 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 GAP90216.1 - 6.2e-36 124.0 12.0 6.2e-36 124.0 12.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP90216.1 - 6.3e-13 48.4 4.8 2.1e-12 46.7 4.8 1.8 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAP90216.1 - 9.7e-07 28.0 1.5 1.1e-05 24.6 1.5 2.1 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 GAP90216.1 - 5.2e-06 25.1 6.8 1e-05 24.1 1.9 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector TRI12 PF06609.13 GAP90216.1 - 0.0024 16.4 0.8 0.0036 15.8 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cu_amine_oxid PF01179.20 GAP90217.1 - 6.4e-152 506.2 0.0 8.1e-152 505.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 GAP90217.1 - 3.6e-06 27.1 0.0 6.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 GAP90217.1 - 0.0058 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Glyco_hydro_3_C PF01915.22 GAP90218.1 - 1e-44 153.0 0.0 1.6e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAP90218.1 - 2.8e-41 141.9 0.0 4.2e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAP90218.1 - 4e-25 87.7 0.4 8.3e-25 86.7 0.4 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain SSF PF00474.17 GAP90219.1 - 1.3e-20 73.7 28.7 2.1e-20 73.0 28.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Glyco_hydro_88 PF07470.13 GAP90220.1 - 2.2e-86 290.1 0.9 2.5e-86 289.9 0.9 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 GAP90221.1 - 2.3e-30 105.7 21.5 2.3e-30 105.7 21.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily RRM_1 PF00076.22 GAP90222.1 - 5.1e-14 51.8 0.0 7.4e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAP90222.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cupin_2 PF07883.11 GAP90223.1 - 0.017 14.8 0.0 0.35 10.6 0.0 2.3 1 1 0 1 1 1 0 Cupin domain Cupin_1 PF00190.22 GAP90223.1 - 0.042 13.5 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Cupin Glyco_hydro_16 PF00722.21 GAP90224.1 - 3e-14 52.9 0.7 5.2e-14 52.1 0.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 GAP90225.1 - 1.2e-50 172.2 8.1 3.4e-50 170.7 7.9 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 GAP90225.1 - 1.8e-06 27.9 0.0 9e-06 25.6 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 GAP90225.1 - 0.0013 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 GAP90225.1 - 0.019 14.8 0.3 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Glyco_hydro_16 PF00722.21 GAP90226.1 - 2.5e-34 118.3 3.4 3.9e-34 117.7 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_S41 PF03572.18 GAP90227.1 - 0.0039 16.8 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 Methyltransf_23 PF13489.6 GAP90229.1 - 4.7e-12 46.1 0.0 6.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP90229.1 - 4.4e-10 40.1 0.0 9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP90229.1 - 6.6e-10 39.5 0.0 1.4e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP90229.1 - 2.2e-06 27.5 0.0 7.4e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 GAP90229.1 - 0.00048 19.6 0.0 0.00097 18.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 GAP90229.1 - 0.0027 18.4 0.0 0.014 16.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAP90229.1 - 0.027 13.8 0.0 0.066 12.5 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain MTS PF05175.14 GAP90229.1 - 0.032 13.8 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 GAP90229.1 - 0.044 13.9 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 GAP90229.1 - 0.055 13.2 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase QRPTase_C PF01729.19 GAP90230.1 - 1.2e-54 184.6 0.1 1.5e-54 184.3 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 GAP90230.1 - 7.6e-17 61.2 0.0 2.6e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain MFS_1 PF07690.16 GAP90231.1 - 9.9e-39 133.2 24.3 1.4e-38 132.7 24.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Gln-synt_C PF00120.24 GAP90232.1 - 1.2e-83 281.0 0.0 1.4e-83 280.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 GAP90232.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain adh_short_C2 PF13561.6 GAP90233.1 - 4.8e-55 186.7 0.0 5.6e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP90233.1 - 5.6e-39 133.6 0.0 6.9e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP90233.1 - 7.9e-12 45.4 0.4 1.2e-11 44.9 0.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAP90233.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 GAP90233.1 - 0.0089 16.7 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 GAP90233.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 GAP90233.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RecC_C PF17946.1 GAP90233.1 - 0.036 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 RecC C-terminal domain ChuX_HutX PF06228.13 GAP90233.1 - 0.065 13.0 0.0 9.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX 3Beta_HSD PF01073.19 GAP90233.1 - 0.1 11.6 0.0 0.28 10.2 0.0 1.7 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_12 PF08242.12 GAP90233.1 - 0.13 13.0 0.0 0.27 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ICL PF00463.21 GAP90234.1 - 4.6e-196 652.4 0.1 5.3e-196 652.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Citrate_synt PF00285.21 GAP90235.1 - 2e-101 339.7 0.0 2.4e-101 339.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF4360 PF14273.6 GAP90236.1 - 2e-67 226.5 4.4 2.3e-67 226.3 4.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) LigB PF02900.18 GAP90237.1 - 2.2e-38 131.9 0.0 2.6e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase TcdB_toxin_midC PF12255.8 GAP90237.1 - 0.017 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/C-terminal region Metallophos_C PF14008.6 GAP90237.1 - 0.049 14.5 0.1 0.21 12.5 0.0 2.0 2 0 0 2 2 2 0 Iron/zinc purple acid phosphatase-like protein C Abhydrolase_2 PF02230.16 GAP90238.1 - 4.8e-62 209.6 0.0 6.2e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 GAP90238.1 - 2.5e-05 23.9 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAP90238.1 - 3.2e-05 23.3 0.3 0.16 11.2 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DUF2920 PF11144.8 GAP90238.1 - 0.00014 21.2 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) Abhydrolase_6 PF12697.7 GAP90238.1 - 0.0002 22.0 0.3 0.00027 21.6 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 GAP90238.1 - 0.0014 18.3 0.0 0.0072 16.0 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 GAP90238.1 - 0.0018 18.1 0.2 0.22 11.4 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP90238.1 - 0.013 15.0 0.6 0.26 10.7 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family DUF2974 PF11187.8 GAP90238.1 - 0.059 12.9 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 GAP90238.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) IMD PF08397.11 GAP90239.1 - 4.9e-05 22.8 1.1 0.0022 17.4 0.2 2.1 2 0 0 2 2 2 2 IRSp53/MIM homology domain DUF1687 PF07955.11 GAP90241.1 - 4.7e-35 120.9 0.2 6.1e-35 120.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) L51_S25_CI-B8 PF05047.16 GAP90243.1 - 5.5e-14 51.8 0.0 6.9e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CaM_binding PF07839.11 GAP90243.1 - 0.12 13.1 0.0 0.13 13.0 0.0 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain HopJ PF08888.11 GAP90244.1 - 0.18 12.0 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 HopJ type III effector protein AAA PF00004.29 GAP90245.1 - 9.6e-31 106.9 0.0 2.3e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAP90245.1 - 4e-06 26.5 0.1 8e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 GAP90245.1 - 0.00026 21.1 0.0 0.00062 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAP90245.1 - 0.0011 19.3 0.3 0.1 12.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GAP90245.1 - 0.0071 16.3 0.1 0.028 14.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAP90245.1 - 0.0095 16.3 0.2 0.5 10.7 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 GAP90245.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 GAP90245.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 GAP90245.1 - 0.023 14.2 0.1 1.2 8.5 0.1 2.2 1 1 1 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 GAP90245.1 - 0.026 15.0 0.0 0.076 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 GAP90245.1 - 0.03 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 GAP90245.1 - 0.041 14.3 0.4 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 GAP90245.1 - 0.091 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 GAP90245.1 - 0.11 11.8 0.2 0.23 10.8 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 GAP90245.1 - 0.13 12.1 0.0 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 GAP90245.1 - 0.14 12.4 1.3 2 8.7 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain TsaE PF02367.17 GAP90245.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 GAP90245.1 - 0.18 11.0 0.0 0.39 9.9 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA PF00004.29 GAP90247.1 - 9.1e-28 97.3 0.0 5e-14 52.8 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 GAP90247.1 - 7.2e-12 45.4 0.4 0.00083 19.1 0.1 3.4 3 0 0 3 3 3 3 IstB-like ATP binding protein AAA_5 PF07728.14 GAP90247.1 - 9.6e-10 38.6 0.1 0.0062 16.5 0.0 3.9 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP90247.1 - 1.1e-08 35.5 0.5 0.084 13.2 0.1 5.4 3 2 0 3 3 3 2 AAA domain RuvB_N PF05496.12 GAP90247.1 - 4.9e-08 32.9 0.1 0.32 10.7 0.0 4.0 3 2 0 3 3 3 3 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_6 PF17866.1 GAP90247.1 - 5.8e-08 32.8 13.4 3.1e-07 30.5 1.8 4.8 4 1 0 4 4 4 1 AAA lid domain Mg_chelatase PF01078.21 GAP90247.1 - 1.7e-07 30.8 0.0 0.17 11.3 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 GAP90247.1 - 2.4e-07 30.6 0.0 0.067 12.9 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 GAP90247.1 - 7.3e-07 29.7 0.4 0.45 10.9 0.0 4.5 4 0 0 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 GAP90247.1 - 1.3e-05 25.4 1.9 0.28 11.3 0.0 4.1 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.6 GAP90247.1 - 2.3e-05 24.8 0.0 0.52 10.6 0.1 3.7 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 GAP90247.1 - 5.7e-05 22.9 0.7 1.9 8.2 0.1 3.7 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 GAP90247.1 - 0.00012 21.9 0.2 2.7 7.6 0.0 4.7 4 1 0 4 4 4 1 Sigma-54 interaction domain RNA_helicase PF00910.22 GAP90247.1 - 0.00014 22.2 0.0 0.2 12.1 0.0 3.4 4 0 0 4 4 3 1 RNA helicase Torsin PF06309.11 GAP90247.1 - 0.00021 21.4 0.0 0.71 10.0 0.0 3.3 3 0 0 3 3 3 1 Torsin AAA_28 PF13521.6 GAP90247.1 - 0.0015 18.8 2.3 1.4 9.1 0.0 3.8 3 0 0 3 3 3 2 AAA domain MCM PF00493.23 GAP90247.1 - 0.0038 16.4 0.1 1.3 8.0 0.0 2.6 2 1 0 2 2 2 1 MCM P-loop domain PhoH PF02562.16 GAP90247.1 - 0.0048 16.4 0.2 8.9 5.7 0.0 3.6 4 0 0 4 4 4 0 PhoH-like protein AAA_7 PF12775.7 GAP90247.1 - 0.0057 16.2 0.1 0.89 9.0 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region TniB PF05621.11 GAP90247.1 - 0.017 14.6 0.0 9.1 5.6 0.0 4.5 4 1 1 5 5 5 0 Bacterial TniB protein DNA_pol3_delta2 PF13177.6 GAP90247.1 - 0.039 13.7 0.0 10 5.9 0.0 2.8 3 0 0 3 3 2 0 DNA polymerase III, delta subunit AAA_17 PF13207.6 GAP90247.1 - 0.19 12.2 3.1 11 6.4 0.1 3.9 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 GAP90247.1 - 0.36 10.6 0.0 0.36 10.6 0.0 5.3 6 0 0 6 6 6 0 AAA domain AAA_18 PF13238.6 GAP90247.1 - 0.64 10.6 16.1 0.95 10.0 0.0 5.1 5 1 0 5 5 3 0 AAA domain WD40 PF00400.32 GAP90248.1 - 2.3e-65 214.9 37.5 2.2e-08 34.6 0.0 11.2 10 0 0 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP90248.1 - 1.3e-25 89.5 0.6 0.00095 19.4 0.0 10.6 4 3 7 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain NACHT_N PF17100.5 GAP90248.1 - 1.4e-17 64.3 0.0 1.3e-16 61.2 0.0 2.2 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ge1_WD40 PF16529.5 GAP90248.1 - 2.2e-15 56.4 6.8 0.083 11.8 0.1 8.7 3 2 5 9 9 9 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAP90248.1 - 7.5e-10 38.5 1.2 9.9 6.2 0.0 8.2 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 GAP90248.1 - 0.00018 20.2 0.5 0.051 12.1 0.1 3.3 3 0 0 3 3 3 2 Cytochrome D1 heme domain Nbas_N PF15492.6 GAP90248.1 - 0.00053 19.4 2.3 14 4.9 0.0 6.0 4 3 3 7 7 7 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 GAP90248.1 - 0.0021 18.0 0.0 0.43 10.4 0.0 3.7 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 GAP90248.1 - 0.25 11.0 8.2 90 2.9 0.1 6.1 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature adh_short PF00106.25 GAP90250.1 - 1.7e-09 37.4 0.0 2.1e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP90250.1 - 1.8e-08 34.2 0.0 2.1e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP90250.1 - 0.0016 18.4 0.0 0.002 18.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 GAP90250.1 - 0.098 12.7 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 GAP90251.1 - 3.3e-21 75.5 2.9 7.4e-21 74.3 2.1 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAP90251.1 - 1.8e-08 34.3 2.5 2e-08 34.2 1.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like p450 PF00067.22 GAP90252.1 - 3.3e-44 151.4 0.0 4.2e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 GAP90253.1 - 3.1e-23 82.4 2.4 4.9e-23 81.7 2.4 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family AceK PF06315.11 GAP90254.1 - 0.029 12.9 0.0 0.037 12.5 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) DUF1206 PF06724.11 GAP90254.1 - 0.1 12.7 0.3 0.1 12.7 0.3 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) FAD_binding_4 PF01565.23 GAP90255.1 - 7.9e-23 80.7 2.6 1.3e-22 80.0 2.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP90255.1 - 0.011 15.8 0.1 0.024 14.7 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like MFS_1 PF07690.16 GAP90256.1 - 3.6e-37 128.1 52.5 3.6e-37 128.1 52.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP90256.1 - 2.4e-11 42.8 13.6 2.4e-11 42.8 13.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP90256.1 - 8.4e-11 41.4 30.0 2.7e-10 39.7 10.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter p450 PF00067.22 GAP90257.1 - 9.5e-40 136.7 0.0 1.3e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LysM PF01476.20 GAP90258.1 - 1.2e-05 25.3 0.0 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 2 LysM domain Csm1 PF12539.8 GAP90259.1 - 4.5e-32 110.5 0.0 1.1e-31 109.3 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Rootletin PF15035.6 GAP90259.1 - 0.0076 16.3 10.9 0.0076 16.3 10.9 2.1 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion NPV_P10 PF05531.12 GAP90259.1 - 0.085 13.3 0.9 0.34 11.4 0.6 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein eIF3_N PF09440.10 GAP90259.1 - 0.21 12.0 9.3 0.039 14.4 4.8 2.2 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain DUF1744 PF08490.12 GAP90259.1 - 0.47 9.0 2.4 18 3.7 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1744) Fib_alpha PF08702.10 GAP90259.1 - 0.48 10.6 9.5 4.2 7.6 5.4 3.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Ribonuc_P_40 PF08584.11 GAP90259.1 - 2.4 7.4 5.0 0.43 9.8 1.1 1.7 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit Med9 PF07544.13 GAP90259.1 - 3.1 8.0 10.1 3.1 8.0 3.4 3.8 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.12 GAP90259.1 - 3.4 7.7 8.3 0.88 9.6 3.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) VPS11_C PF12451.8 GAP90259.1 - 7.4 6.9 7.4 2.2 8.6 1.4 3.1 2 1 1 3 3 3 0 Vacuolar protein sorting protein 11 C terminal TMPIT PF07851.13 GAP90259.1 - 7.8 5.6 11.2 0.59 9.3 4.4 2.2 1 1 1 2 2 2 0 TMPIT-like protein PigN PF04987.14 GAP90260.1 - 9.4e-161 535.7 28.5 9.4e-161 535.7 28.5 1.8 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 GAP90260.1 - 3.1e-09 36.9 4.0 2e-07 30.9 4.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAP90260.1 - 3.6e-09 36.5 0.2 5.7e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 GAP90260.1 - 4e-05 23.1 0.1 6.4e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Fungal_trans PF04082.18 GAP90261.1 - 2.1e-35 122.1 0.0 5.3e-35 120.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP90261.1 - 4.7e-08 33.0 9.2 8.5e-08 32.2 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.20 GAP90262.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 LysM domain NAD_binding_2 PF03446.15 GAP90263.1 - 5.9e-31 107.8 0.1 8.4e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 GAP90263.1 - 4.8e-09 36.7 0.1 8.8e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 GAP90263.1 - 3.5e-08 33.6 0.1 5.4e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 GAP90263.1 - 4.3e-08 33.4 0.0 6.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sacchrp_dh_NADP PF03435.18 GAP90263.1 - 0.0016 18.7 0.1 0.0038 17.5 0.1 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 GAP90263.1 - 0.0055 17.5 0.0 0.0089 16.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.10 GAP90263.1 - 0.008 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAP90263.1 - 0.012 15.5 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding UDPG_MGDP_dh_N PF03721.14 GAP90263.1 - 0.016 14.8 0.4 0.043 13.4 0.4 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain OCD_Mu_crystall PF02423.15 GAP90263.1 - 0.017 14.0 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family TrkA_N PF02254.18 GAP90263.1 - 0.027 14.7 0.3 0.072 13.3 0.3 1.6 1 1 0 1 1 1 0 TrkA-N domain IlvN PF07991.12 GAP90263.1 - 0.055 13.0 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain P34-Arc PF04045.14 GAP90264.1 - 2.1e-107 358.3 0.4 2.5e-107 358.0 0.4 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF4178 PF13785.6 GAP90264.1 - 0.044 13.9 0.4 0.1 12.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4178) WD40 PF00400.32 GAP90265.1 - 7.6e-46 153.2 21.5 1.7e-05 25.5 0.3 11.4 12 1 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 GAP90265.1 - 5.4e-17 62.0 0.1 1e-16 61.1 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 GAP90265.1 - 4.2e-16 59.0 3.5 0.19 12.0 0.0 8.6 4 2 4 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP90265.1 - 2.8e-05 23.2 0.2 0.96 8.3 0.0 4.8 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAP90265.1 - 8.8e-05 22.0 0.0 0.43 9.9 0.0 3.3 3 0 0 3 3 3 2 WD40-like domain RAB3GAP2_N PF14655.6 GAP90265.1 - 0.0041 16.4 0.0 1.8 7.7 0.0 2.8 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_N PF08801.11 GAP90265.1 - 0.008 15.0 1.5 4.8 5.8 0.0 3.9 4 1 1 5 5 5 2 Nup133 N terminal like Nup160 PF11715.8 GAP90265.1 - 0.045 12.4 1.5 3.4 6.2 0.0 4.2 6 1 0 6 6 6 0 Nucleoporin Nup120/160 zf-RING_2 PF13639.6 GAP90266.1 - 4.5e-11 42.9 4.0 8.6e-11 42.0 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 GAP90266.1 - 2.4e-09 37.3 3.3 5.7e-09 36.1 3.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 GAP90266.1 - 1.1e-06 28.6 0.4 1.1e-06 28.6 0.4 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 GAP90266.1 - 2.5e-06 27.2 5.1 7.7e-06 25.7 5.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 GAP90266.1 - 1.4e-05 24.9 3.0 2.4e-05 24.2 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAP90266.1 - 2.6e-05 24.0 2.3 5.3e-05 23.0 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP90266.1 - 0.00013 21.7 3.6 0.00025 20.9 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAP90266.1 - 0.00024 20.9 3.6 0.00048 19.9 3.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 GAP90266.1 - 0.0006 19.8 4.3 0.0014 18.6 4.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 GAP90266.1 - 0.0018 18.4 3.8 0.03 14.5 3.8 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_11 PF17123.5 GAP90266.1 - 0.002 17.8 0.6 0.0073 16.0 0.6 2.0 1 1 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 GAP90266.1 - 0.0076 15.8 0.6 0.0076 15.8 0.6 2.0 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 GAP90266.1 - 0.11 12.3 0.7 0.25 11.2 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 GAP90266.1 - 1.1 9.5 3.9 2.6 8.3 3.9 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Methyltransf_31 PF13847.6 GAP90267.1 - 9e-10 38.5 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP90267.1 - 2.2e-09 37.9 0.0 5.3e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP90267.1 - 5.6e-09 36.6 0.0 1.2e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP90267.1 - 1.2e-08 35.0 0.0 2.1e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP90267.1 - 1.6e-05 25.4 0.0 3.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP90267.1 - 0.00062 19.2 0.0 0.00097 18.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 GAP90267.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain DUF3775 PF12616.8 GAP90267.1 - 0.02 14.9 0.1 0.052 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) zf-C2H2 PF00096.26 GAP90268.1 - 0.0036 17.7 3.7 0.27 11.8 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP90268.1 - 0.02 15.7 2.2 6.9 7.8 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 GAP90268.1 - 0.071 12.5 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Cullin PF00888.22 GAP90269.1 - 9e-23 80.7 0.0 1.8e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 GAP90269.1 - 6.2e-21 74.7 0.1 2.5e-20 72.7 0.1 2.1 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 ABC_tran PF00005.27 GAP90270.1 - 1.1e-36 126.4 0.0 1.5e-20 74.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAP90270.1 - 1.2e-13 51.3 3.7 2.5e-13 50.3 3.7 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 GAP90270.1 - 1.9e-05 24.3 0.5 0.018 14.8 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAP90270.1 - 3.1e-05 24.4 0.6 0.37 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 GAP90270.1 - 0.00012 22.0 0.5 0.17 11.8 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAP90270.1 - 0.0017 18.4 0.4 0.94 9.6 0.1 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.6 GAP90270.1 - 0.0034 17.7 2.2 1.7 9.0 0.3 2.6 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 GAP90270.1 - 0.0067 15.5 0.2 2.1 7.3 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.19 GAP90270.1 - 0.0089 15.5 0.0 0.36 10.2 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 GAP90270.1 - 0.013 14.8 0.4 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 GAP90270.1 - 0.017 14.7 1.0 2.4 7.7 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PIF1 PF05970.14 GAP90270.1 - 0.057 12.6 0.1 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase AAA_30 PF13604.6 GAP90270.1 - 0.063 13.0 0.9 8.2 6.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 GAP90270.1 - 0.12 12.2 0.3 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 GAP90270.1 - 0.13 12.3 0.2 2.5 8.1 0.2 2.2 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 GAP90270.1 - 0.28 11.1 1.5 19 5.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain DAP3 PF10236.9 GAP90270.1 - 0.33 10.1 1.9 3.3 6.8 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 GAP90270.1 - 0.47 9.6 1.5 9.1 5.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF3035 PF11233.8 GAP90271.1 - 0.064 13.5 0.4 0.11 12.8 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) Baculo_PEP_C PF04513.12 GAP90272.1 - 0.0038 17.3 0.5 0.0074 16.3 0.5 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF885 PF05960.11 GAP90272.1 - 0.011 15.4 0.2 0.013 15.2 0.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Ribosomal_L9_N PF01281.19 GAP90273.1 - 1.8e-11 43.4 0.0 3.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 GAP90273.1 - 0.0063 17.0 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain RCDG1 PF15725.5 GAP90273.1 - 9.1 6.8 8.6 5 7.6 5.1 2.1 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein ATG11 PF10377.9 GAP90274.1 - 8.9e-42 142.2 0.1 8.9e-42 142.2 0.1 3.7 4 1 0 4 4 3 1 Autophagy-related protein 11 ERM PF00769.19 GAP90274.1 - 0.00028 20.8 12.8 0.00028 20.8 12.8 5.2 4 1 1 5 5 4 1 Ezrin/radixin/moesin family Tropomyosin PF00261.20 GAP90274.1 - 0.0029 17.0 11.2 0.0029 17.0 11.2 6.7 5 1 1 7 7 7 1 Tropomyosin TACC_C PF05010.14 GAP90274.1 - 0.0057 16.5 8.5 0.0057 16.5 8.5 5.1 2 2 3 6 6 6 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Laminin_II PF06009.12 GAP90274.1 - 0.03 14.4 0.2 0.03 14.4 0.2 8.4 5 2 5 10 10 10 0 Laminin Domain II Fib_alpha PF08702.10 GAP90274.1 - 0.21 11.8 52.4 0.78 9.9 3.4 6.6 5 2 2 7 7 6 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 GAP90274.1 - 0.26 10.6 53.3 0.074 12.4 11.4 4.7 2 2 2 4 4 4 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 GAP90274.1 - 0.33 9.8 67.7 0.33 9.8 16.5 6.4 4 1 1 6 6 6 0 Spc7 kinetochore protein CAP_N PF01213.19 GAP90274.1 - 0.58 9.6 21.2 0.79 9.1 8.8 3.4 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal FPP PF05911.11 GAP90274.1 - 0.58 8.3 62.2 0.05 11.8 14.8 3.6 1 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil EzrA PF06160.12 GAP90274.1 - 0.61 8.2 50.9 0.36 9.0 19.7 4.7 4 1 0 4 4 4 0 Septation ring formation regulator, EzrA HOOK PF05622.12 GAP90274.1 - 0.74 7.9 55.7 0.046 11.9 4.7 4.6 2 1 2 4 4 4 0 HOOK protein Filament PF00038.21 GAP90274.1 - 1.6 8.2 61.8 0.12 11.9 30.4 4.5 2 1 1 3 3 3 0 Intermediate filament protein DUF1664 PF07889.12 GAP90274.1 - 5.6 7.0 45.9 8.2 6.5 1.1 8.5 6 3 3 9 9 9 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 GAP90274.1 - 7 6.7 55.0 0.074 13.1 8.1 4.8 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 GAP90275.1 - 5.3e-35 120.2 2.3 2.4e-33 114.9 0.3 2.0 2 0 0 2 2 2 2 Centromere protein H (CENP-H) DUF1192 PF06698.11 GAP90275.1 - 0.015 15.3 1.0 2.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TSC22 PF01166.18 GAP90275.1 - 0.043 14.1 0.3 2.2 8.7 0.1 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family ATG16 PF08614.11 GAP90275.1 - 0.12 12.6 5.4 0.33 11.1 0.4 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 GAP90275.1 - 0.78 10.4 4.8 1.9 9.1 0.5 2.8 2 1 1 3 3 3 0 SlyX bZIP_2 PF07716.15 GAP90275.1 - 7 6.8 8.0 21 5.3 0.1 2.8 3 0 0 3 3 3 0 Basic region leucine zipper HMG_box PF00505.19 GAP90276.1 - 6.1e-25 87.4 0.8 8.4e-25 87.0 0.8 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAP90276.1 - 1.3e-17 64.1 1.3 1.9e-17 63.6 1.3 1.2 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 GAP90276.1 - 0.0015 19.1 1.2 0.004 17.7 0.0 1.9 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 GAP90276.1 - 0.0096 15.9 0.4 0.02 14.9 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CorA PF01544.18 GAP90278.1 - 7.9e-06 25.4 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SUR7 PF06687.12 GAP90278.1 - 0.015 14.9 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 SUR7/PalI family AAA PF00004.29 GAP90279.1 - 3.1e-17 63.3 0.0 6e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP90279.1 - 0.00026 21.4 0.1 0.00085 19.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP90279.1 - 0.00057 20.2 0.9 0.01 16.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GAP90279.1 - 0.0011 18.9 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAP90279.1 - 0.0016 19.0 0.0 0.0052 17.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAP90279.1 - 0.0096 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain CPT PF07931.12 GAP90279.1 - 0.032 14.1 0.0 0.31 10.8 0.0 2.3 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.6 GAP90279.1 - 0.13 12.3 0.0 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAP90279.1 - 0.13 12.5 0.6 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 GAP90279.1 - 0.16 11.8 0.2 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Exo_endo_phos PF03372.23 GAP90281.1 - 3.2e-11 43.2 1.7 4.6e-11 42.7 1.7 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RSN1_7TM PF02714.15 GAP90282.1 - 6.1e-78 261.9 21.4 1e-77 261.2 21.4 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAP90282.1 - 6.8e-41 139.6 2.6 1.7e-40 138.3 2.6 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAP90282.1 - 1.2e-37 129.8 0.0 1.7e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter TMEM192 PF14802.6 GAP90282.1 - 0.4 9.7 2.0 1.9 7.5 0.1 2.3 2 0 0 2 2 2 0 TMEM192 family PAPS_reduct PF01507.19 GAP90284.1 - 1.2e-27 97.0 0.0 8.2e-21 74.8 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family E1-E2_ATPase PF00122.20 GAP90285.1 - 3e-34 118.1 22.5 1.7e-29 102.7 0.9 3.3 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAP90285.1 - 3.5e-30 105.0 2.3 3.5e-30 105.0 2.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 GAP90285.1 - 3.7e-22 78.2 0.0 7.4e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 GAP90285.1 - 7e-20 72.2 0.0 3.8e-15 56.8 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAP90285.1 - 2.3e-16 59.2 0.1 8.7e-16 57.4 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAP90285.1 - 9e-07 28.9 0.2 6e-05 22.9 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PHD PF00628.29 GAP90287.1 - 2.9e-08 33.5 9.0 5.5e-08 32.6 9.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 GAP90287.1 - 0.014 14.9 5.2 0.027 14.0 5.2 1.4 1 0 0 1 1 1 0 PHD-finger HMG_box PF00505.19 GAP90288.1 - 0.0011 19.3 0.2 0.024 15.0 0.2 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 GAP90288.1 - 0.14 11.4 0.1 0.14 11.4 0.1 1.5 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 HMG-box TFIIA PF03153.13 GAP90289.1 - 0.87 9.5 7.9 1.2 9.1 7.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec20 PF03908.13 GAP90290.1 - 6.1e-17 61.3 0.3 6.1e-17 61.3 0.3 2.6 4 0 0 4 4 4 1 Sec20 DASH_Dam1 PF08653.10 GAP90290.1 - 4.3 7.2 7.9 1.3 8.8 0.5 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 MRP_L53 PF10780.9 GAP90291.1 - 9e-21 73.8 0.2 1.2e-20 73.4 0.2 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.19 GAP90292.1 - 1.4e-58 197.2 0.2 2e-58 196.8 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Zn_clus PF00172.18 GAP90293.1 - 2.3e-05 24.4 7.1 4.5e-05 23.5 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ppx-GppA PF02541.16 GAP90295.1 - 1.1e-35 123.4 0.0 2.9e-35 122.1 0.0 1.6 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Peptidase_C15 PF01470.17 GAP90296.1 - 0.015 15.5 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Pyroglutamyl peptidase Peptidase_C15 PF01470.17 GAP90297.1 - 4.9e-05 23.6 0.0 0.00012 22.3 0.0 1.6 1 1 0 1 1 1 1 Pyroglutamyl peptidase Oxidored_FMN PF00724.20 GAP90298.1 - 1.2e-69 235.2 0.0 1.5e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cytochrom_C1 PF02167.15 GAP90300.1 - 2.7e-92 308.4 0.0 3.2e-92 308.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrom_C PF00034.21 GAP90300.1 - 0.026 15.7 0.2 0.15 13.2 0.1 2.2 2 1 0 2 2 2 0 Cytochrome c Cytochrome_CBB3 PF13442.6 GAP90300.1 - 0.038 14.3 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Histone PF00125.24 GAP90301.1 - 4.1 7.8 11.4 0.25 11.7 5.4 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DAHP_synth_1 PF00793.20 GAP90302.1 - 1.1e-93 313.1 0.1 1.5e-93 312.7 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Far-17a_AIG1 PF04750.14 GAP90303.1 - 6.9e-50 169.2 12.1 7.9e-50 169.0 12.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pro_isomerase PF00160.21 GAP90304.1 - 1.1e-51 175.2 0.9 2.2e-51 174.2 0.1 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 GAP90304.1 - 5.5e-11 42.8 0.1 6.8e-05 23.6 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP90304.1 - 0.0015 18.8 0.0 0.015 15.5 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP90304.1 - 0.018 14.0 0.2 0.21 10.5 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Fungal_trans_2 PF11951.8 GAP90305.1 - 1e-54 185.9 0.0 1.5e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP90305.1 - 2.3e-08 34.0 8.3 2.3e-08 34.0 8.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.18 GAP90306.1 - 4.6e-122 407.4 0.1 5.3e-122 407.2 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 GAP90306.1 - 1.3e-05 24.5 1.4 1.9e-05 24.0 1.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAP90306.1 - 2.3e-05 23.6 1.3 0.00023 20.3 0.6 2.4 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 GAP90306.1 - 4.6e-05 22.8 0.9 0.036 13.4 0.5 2.3 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG IGPS PF00218.21 GAP90306.1 - 0.0084 15.3 0.0 0.021 14.0 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 GAP90306.1 - 0.013 15.0 0.1 0.046 13.2 0.1 1.9 1 1 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 GAP90306.1 - 0.031 13.7 3.0 0.045 13.1 3.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase DUF2071 PF09844.9 GAP90306.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) SLD5_C PF16922.5 GAP90307.1 - 1.3e-12 47.7 0.0 2.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 GAP90307.1 - 4.5e-08 33.5 0.1 1.3e-07 32.1 0.1 1.7 2 0 0 2 2 2 1 GINS complex protein TRPM_tetra PF16519.5 GAP90307.1 - 0.072 13.2 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Abhydrolase_6 PF12697.7 GAP90308.1 - 7.6e-25 88.8 5.7 7.6e-25 88.8 5.7 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP90308.1 - 1.6e-12 47.6 0.1 5.1e-12 46.0 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP90308.1 - 9.5e-10 38.1 0.2 1.5e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAP90308.1 - 0.00056 20.1 0.1 0.0011 19.1 0.1 1.5 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 GAP90308.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 GAP90308.1 - 0.21 11.1 0.0 3.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Dus PF01207.17 GAP90309.1 - 2.1e-06 27.1 0.0 2.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Pkinase PF00069.25 GAP90311.1 - 9e-63 212.1 0.0 2.5e-62 210.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP90311.1 - 6.1e-30 104.4 0.0 1.4e-29 103.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 GAP90311.1 - 1.9e-10 41.0 0.0 4.7e-08 33.3 0.1 2.8 2 0 0 2 2 2 1 FHA domain Kdo PF06293.14 GAP90311.1 - 0.00085 18.7 0.5 0.0016 17.8 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 GAP90311.1 - 0.01 15.5 0.2 0.019 14.6 0.2 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 GAP90311.1 - 0.044 13.7 0.4 0.044 13.7 0.4 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 GAP90311.1 - 0.046 13.0 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 Kinase-like CAP_N PF01213.19 GAP90312.1 - 0.099 12.1 19.9 0.34 10.3 3.5 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GAP90312.1 - 0.35 10.9 21.0 0.58 10.2 5.3 3.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 STT3 PF02516.14 GAP90313.1 - 8.1e-143 476.9 34.3 8.3e-138 460.4 32.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.12 GAP90314.1 - 4.6e-24 84.6 0.4 4.9e-24 84.5 0.4 1.0 1 0 0 1 1 1 1 ATP synthase E chain WD40 PF00400.32 GAP90315.1 - 7.1e-06 26.7 9.7 1.7 9.6 0.3 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat NUP214 PF16755.5 GAP90316.1 - 0.00022 20.6 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 GAP90316.1 - 0.0031 17.8 0.0 0.009 16.3 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Proteasome PF00227.26 GAP90317.1 - 3.4e-47 160.4 0.0 4.5e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 GAP90317.1 - 1e-14 53.6 0.3 1e-14 53.6 0.3 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Trehalase PF01204.18 GAP90318.1 - 1.1e-115 387.4 3.5 3.1e-106 356.2 0.1 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 GAP90318.1 - 0.00021 20.3 0.0 0.00041 19.4 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Acetyltransf_3 PF13302.7 GAP90319.1 - 4.4e-16 59.8 0.0 7.5e-16 59.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAP90319.1 - 0.013 15.6 0.0 0.041 14.0 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP90319.1 - 0.023 14.9 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 GAP90319.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain COPIIcoated_ERV PF07970.12 GAP90320.1 - 2.5e-87 292.3 0.1 3.5e-87 291.9 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAP90320.1 - 3.1e-30 104.3 0.2 1.6e-29 102.1 0.0 2.2 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sel1 PF08238.12 GAP90321.1 - 2e-10 41.0 5.5 0.019 15.7 0.1 3.8 3 0 0 3 3 3 3 Sel1 repeat Beta_elim_lyase PF01212.21 GAP90322.1 - 7.9e-65 219.0 0.0 1e-64 218.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 GAP90322.1 - 0.0015 17.6 0.1 0.0028 16.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 GAP90322.1 - 0.0037 16.5 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 GAP90322.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Glyco_transf_17 PF04724.13 GAP90323.1 - 3.8e-53 180.8 0.4 1e-52 179.3 0.4 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 17 Nsp3_PL2pro PF12124.8 GAP90323.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain PurS PF02700.14 GAP90324.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase AIRC PF00731.20 GAP90325.1 - 5.9e-59 197.9 1.0 1.2e-58 196.9 1.0 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 GAP90325.1 - 9.1e-47 158.8 0.0 1.5e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 GAP90325.1 - 9.9e-14 50.8 0.4 1.8e-13 50.0 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 GAP90325.1 - 0.0022 17.5 0.0 0.0055 16.2 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PrpR_N PF06506.11 GAP90325.1 - 0.0036 16.9 0.1 0.046 13.3 0.0 2.4 2 0 0 2 2 2 1 Propionate catabolism activator XdhC_C PF13478.6 GAP90325.1 - 0.0067 16.9 0.1 1.2 9.6 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain Fe-ADH PF00465.19 GAP90325.1 - 0.077 11.8 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase 2-Hacid_dh_C PF02826.19 GAP90325.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asp_Glu_race PF01177.22 GAP90325.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase Ribosomal_S8 PF00410.19 GAP90326.1 - 3.4e-20 72.3 0.0 5e-20 71.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Prefoldin PF02996.17 GAP90327.1 - 1.4e-25 89.5 0.0 1.8e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit GIT_CC PF16559.5 GAP90327.1 - 0.00096 19.0 1.7 0.0016 18.3 1.7 1.4 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor Prefoldin_2 PF01920.20 GAP90327.1 - 0.005 16.8 0.5 3.3 7.7 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit CEP63 PF17045.5 GAP90327.1 - 0.023 14.6 2.6 0.88 9.4 0.1 2.0 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF1192 PF06698.11 GAP90327.1 - 0.052 13.6 0.1 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Fib_alpha PF08702.10 GAP90327.1 - 0.062 13.5 0.7 1.9 8.7 0.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Tektin PF03148.14 GAP90327.1 - 0.074 11.8 0.5 1.6 7.4 0.0 2.0 2 0 0 2 2 2 0 Tektin family Mst1_SARAH PF11629.8 GAP90327.1 - 0.092 12.8 0.3 0.24 11.5 0.3 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 DUF1664 PF07889.12 GAP90327.1 - 0.095 12.7 1.2 1.3 9.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 GAP90327.1 - 0.1 10.6 0.1 0.12 10.3 0.1 1.1 1 0 0 1 1 1 0 Prominin GNVR PF13807.6 GAP90327.1 - 0.23 11.4 0.1 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase AAA PF00004.29 GAP90329.1 - 1.3e-15 58.0 0.0 2.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 GAP90329.1 - 3.5e-11 43.1 0.0 8.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 GAP90329.1 - 9.9e-10 39.1 0.0 1.1e-08 35.7 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP90329.1 - 6.6e-08 32.9 0.0 1.4e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 GAP90329.1 - 3.1e-05 23.8 0.0 6.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 GAP90329.1 - 0.0055 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAP90329.1 - 0.014 15.2 0.1 0.071 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 GAP90329.1 - 0.027 15.0 0.0 0.087 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAP90329.1 - 0.051 13.5 0.0 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 GAP90329.1 - 0.084 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAP90329.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.6 GAP90329.1 - 0.097 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 GAP90329.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_assoc_2 PF16193.5 GAP90329.1 - 0.11 12.9 0.1 2.9 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA C-terminal domain AAA_3 PF07726.11 GAP90329.1 - 0.11 12.3 0.0 1.4 8.8 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAP90329.1 - 0.17 12.3 0.3 1.2 9.5 0.0 2.6 4 0 0 4 4 2 0 RNA helicase WD40 PF00400.32 GAP90330.1 - 6.1e-45 150.3 16.4 1.9e-09 38.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP90330.1 - 3.8e-07 30.3 0.4 2.4 8.5 0.0 5.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP90330.1 - 0.0025 16.5 2.3 5.2 5.6 0.0 3.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 GAP90330.1 - 0.17 11.2 0.0 0.52 9.6 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain Ank_2 PF12796.7 GAP90331.1 - 1.6e-34 118.4 0.1 2.6e-15 56.8 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP90331.1 - 1.9e-34 117.2 1.8 3.1e-11 43.3 0.0 4.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP90331.1 - 1.9e-32 107.7 0.0 0.00013 22.1 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 GAP90331.1 - 3e-31 107.4 0.3 3.1e-09 37.2 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 GAP90331.1 - 8.5e-26 89.2 0.6 0.00015 22.1 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Glyoxalase_4 PF13669.6 GAP90331.1 - 0.0058 16.9 0.0 0.016 15.4 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 GAP90331.1 - 0.011 16.5 0.4 0.12 13.2 0.1 2.2 2 0 0 2 2 2 0 Glyoxalase-like domain TMF_TATA_bd PF12325.8 GAP90332.1 - 6.7e-38 129.5 8.1 6.7e-38 129.5 8.1 7.4 2 1 4 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 GAP90332.1 - 4.8e-16 58.5 13.5 4.8e-16 58.5 13.5 8.1 5 3 4 9 9 9 1 TATA element modulatory factor 1 DNA binding DUF812 PF05667.11 GAP90332.1 - 3.5e-05 22.9 72.1 0.023 13.6 3.0 3.6 2 1 1 3 3 3 3 Protein of unknown function (DUF812) FliJ PF02050.16 GAP90332.1 - 0.0022 18.2 13.0 0.0022 18.2 13.0 6.3 2 1 4 6 6 6 1 Flagellar FliJ protein NPV_P10 PF05531.12 GAP90332.1 - 4.3 7.9 17.6 5.8 7.5 0.3 5.2 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Holin_BhlA PF10960.8 GAP90332.1 - 10 6.2 10.1 0.24 11.4 0.3 3.3 3 0 0 3 3 3 0 BhlA holin family Ceramidase PF05875.12 GAP90333.1 - 2.4e-94 315.7 14.3 2.7e-94 315.5 14.3 1.0 1 0 0 1 1 1 1 Ceramidase Trp_oprn_chp PF09534.10 GAP90333.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mito_carr PF00153.27 GAP90335.1 - 2.7e-53 177.8 2.9 9.9e-19 67.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAP90335.1 - 0.034 13.3 4.1 2 7.5 0.0 2.9 3 1 0 3 3 3 0 Gammaproteobacterial serine protease Dor1 PF04124.12 GAP90336.1 - 5.5e-56 189.7 0.1 1.8e-47 161.7 0.5 2.6 1 1 1 2 2 2 2 Dor1-like family TRAM_LAG1_CLN8 PF03798.16 GAP90337.1 - 4.9e-51 173.3 13.9 7e-51 172.8 13.9 1.2 1 0 0 1 1 1 1 TLC domain Cytochrom_B561 PF03188.16 GAP90337.1 - 0.013 15.7 0.4 0.028 14.6 0.4 1.6 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 SH3_9 PF14604.6 GAP90338.1 - 1e-34 118.1 7.8 9.6e-13 47.8 0.1 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 GAP90338.1 - 1.2e-34 117.7 5.9 7.9e-13 47.8 0.2 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 GAP90338.1 - 2.5e-34 116.9 0.0 4.6e-34 116.0 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 GAP90338.1 - 8.5e-21 73.4 0.2 1.1e-08 34.6 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SAM_4 PF18017.1 GAP90338.1 - 2.1e-05 24.4 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 GAP90338.1 - 3.1e-05 24.1 2.3 0.0092 16.2 1.1 3.0 3 0 0 3 3 3 1 Bacterial SH3 domain DUF1720 PF08226.11 GAP90338.1 - 0.0063 16.9 21.6 0.0063 16.9 21.6 5.4 1 1 3 4 4 4 2 Domain of unknown function (DUF1720) SH3_10 PF17902.1 GAP90338.1 - 0.039 14.0 0.2 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 SH3 domain MRP PF09387.10 GAP90338.1 - 0.053 13.5 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP A_deaminase PF00962.22 GAP90339.1 - 2.9e-124 414.7 0.1 4.1e-124 414.2 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1556 PF07590.11 GAP90340.1 - 0.0026 18.0 2.9 0.0044 17.3 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1556) Homeodomain PF00046.29 GAP90341.1 - 0.04 13.8 1.0 0.04 13.8 1.0 3.3 3 0 0 3 3 3 0 Homeodomain Spc7 PF08317.11 GAP90341.1 - 0.26 10.1 60.7 0.068 12.0 22.8 3.8 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.8 GAP90341.1 - 2.3 5.6 67.9 0.051 11.1 48.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Lebercilin PF15619.6 GAP90341.1 - 4 7.1 57.0 0.028 14.1 25.8 3.5 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 GAP90342.1 - 0.81 8.5 56.1 0.027 13.4 6.2 4.7 2 1 2 4 4 4 0 Spc7 kinetochore protein DUF3552 PF12072.8 GAP90342.1 - 5.2 6.4 59.3 0.73 9.2 10.3 4.6 1 1 3 4 4 4 0 Domain of unknown function (DUF3552) YopE_N PF09020.10 GAP90343.1 - 0.1 12.9 0.8 0.2 11.9 0.8 1.5 1 0 0 1 1 1 0 YopE, N terminal RepB-RCR_reg PF10723.9 GAP90343.1 - 0.1 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Replication regulatory protein RepB Glycoprotein PF03409.15 GAP90343.1 - 1.1 8.0 5.2 1.7 7.4 5.2 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein FSA_C PF10479.9 GAP90343.1 - 8.6 4.4 6.9 13 3.8 6.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Cu-oxidase_2 PF07731.14 GAP90347.1 - 8.4e-42 142.2 2.0 8.4e-42 142.2 2.0 2.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAP90347.1 - 2.1e-38 131.0 3.3 2.1e-38 131.0 3.3 2.8 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 GAP90347.1 - 5e-37 127.5 1.4 4e-36 124.5 0.4 2.6 2 0 0 2 2 2 1 Multicopper oxidase zf-C2HC5 PF06221.13 GAP90348.1 - 7.8e-22 77.0 5.9 1.2e-21 76.5 5.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type CENP-Q PF13094.6 GAP90348.1 - 3.5 7.8 5.6 12 6.1 0.1 3.0 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Trehalase PF01204.18 GAP90349.1 - 0.0034 16.3 0.0 0.0067 15.3 0.0 1.4 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.16 GAP90349.1 - 0.011 14.5 0.0 0.093 11.5 0.0 2.0 1 1 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain E1-E2_ATPase PF00122.20 GAP90350.1 - 1.1e-18 67.4 0.1 7.6e-18 64.7 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAP90350.1 - 5.7e-15 56.2 2.3 2.9e-09 37.5 2.7 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAP90350.1 - 0.0042 16.8 0.1 0.052 13.3 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAP90350.1 - 0.0082 16.2 0.1 0.034 14.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) bcl-2I13 PF12201.8 GAP90350.1 - 0.094 12.6 0.4 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Bcl2-interacting killer, BH3-domain containing DUF4059 PF13268.6 GAP90350.1 - 0.3 11.5 4.3 11 6.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) Filament PF00038.21 GAP90351.1 - 0.00031 20.4 46.0 0.00031 20.4 46.0 7.6 1 1 7 8 8 8 2 Intermediate filament protein ATG16 PF08614.11 GAP90351.1 - 0.00058 20.1 195.9 0.099 12.9 29.6 7.8 1 1 6 7 7 7 4 Autophagy protein 16 (ATG16) APG6_N PF17675.1 GAP90351.1 - 0.00087 19.8 222.6 0.0099 16.4 24.2 10.5 1 1 9 11 11 11 5 Apg6 coiled-coil region HMMR_N PF15905.5 GAP90351.1 - 0.0043 16.6 27.9 0.0043 16.6 27.9 6.2 1 1 5 6 6 6 3 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 GAP90351.1 - 0.0046 15.9 186.4 0.084 11.7 19.6 8.3 1 1 9 10 10 10 7 Spc7 kinetochore protein Nup54 PF13874.6 GAP90351.1 - 0.0063 16.6 9.5 0.0063 16.6 9.5 9.2 1 1 6 8 8 8 2 Nucleoporin complex subunit 54 GAS PF13851.6 GAP90351.1 - 0.19 11.1 164.6 0.36 10.2 17.2 8.7 1 1 5 7 7 7 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 GAP90351.1 - 1.4 8.6 131.7 0.28 10.9 16.8 11.5 2 1 8 12 12 12 0 Domain of unknown function (DUF4201) WD40_alt PF14077.6 GAP90351.1 - 5.5 6.9 8.8 38 4.2 0.2 5.2 5 0 0 5 5 5 0 Alternative WD40 repeat motif LVIVD PF08309.11 GAP90352.1 - 0.0039 16.5 6.0 1.1 8.7 0.1 4.0 5 0 0 5 5 5 2 LVIVD repeat UPF0052 PF01933.18 GAP90353.1 - 1.4e-53 182.0 0.0 2.1e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Ldh_1_C PF02866.18 GAP90354.1 - 2.1e-45 154.7 0.0 5.2e-45 153.4 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 GAP90354.1 - 2.2e-44 151.0 0.0 3.9e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAP90354.1 - 1.7e-05 24.0 0.0 2.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 GAP90354.1 - 0.093 13.2 0.2 0.35 11.3 0.0 2.0 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 GAP90354.1 - 0.094 12.3 0.1 1.5 8.3 0.2 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase YL1_C PF08265.11 GAP90355.1 - 1.8e-13 50.0 0.0 2.8e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DASH_Dad4 PF08650.10 GAP90356.1 - 1.1e-32 111.9 8.8 1.2e-32 111.7 8.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 GAP90356.1 - 0.026 14.7 0.5 0.03 14.5 0.5 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor LTD PF00932.19 GAP90356.1 - 0.12 12.7 0.1 0.13 12.7 0.1 1.1 1 0 0 1 1 1 0 Lamin Tail Domain DASH_Dad1 PF08649.10 GAP90356.1 - 0.68 10.2 5.4 1.4 9.2 5.4 1.5 1 1 0 1 1 1 0 DASH complex subunit Dad1 Actin PF00022.19 GAP90357.1 - 1.3e-49 168.9 0.0 1.9e-29 102.5 0.0 2.2 2 1 0 2 2 2 2 Actin bZIP_1 PF00170.21 GAP90358.1 - 1.4e-08 34.7 8.6 4.5e-08 33.1 8.5 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAP90358.1 - 0.0088 16.1 9.5 0.13 12.3 6.4 2.5 1 1 1 2 2 2 2 Basic region leucine zipper Leu_zip PF15294.6 GAP90358.1 - 0.016 14.8 0.6 0.023 14.2 0.6 1.1 1 0 0 1 1 1 0 Leucine zipper dsrm PF00035.26 GAP90358.1 - 0.09 13.5 0.4 0.28 11.9 0.1 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding motif FAM199X PF15814.5 GAP90358.1 - 0.18 10.8 4.6 0.34 9.9 4.6 1.4 1 0 0 1 1 1 0 Protein family FAM199X Ribosomal_L30_N PF08079.12 GAP90358.1 - 2.4 8.5 11.4 4.5 7.6 11.4 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Pterin_4a PF01329.19 GAP90360.1 - 0.02 15.0 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase FA_hydroxylase PF04116.13 GAP90361.1 - 7e-25 87.9 18.8 7e-25 87.9 18.8 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily NCA2 PF08637.10 GAP90362.1 - 1.8e-107 358.9 0.0 2.7e-107 358.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ribonuclease_T2 PF00445.18 GAP90363.1 - 1.5e-41 142.6 0.0 2.3e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family MSP1_C PF07462.11 GAP90363.1 - 0.41 9.3 1.2 0.8 8.3 1.2 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RNA_pol_3_Rpc31 PF11705.8 GAP90364.1 - 4.8e-43 148.0 22.6 1.3e-42 146.6 22.6 1.7 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Ion_trans PF00520.31 GAP90365.1 - 1.1e-06 28.0 26.8 2.4e-05 23.7 26.8 2.2 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 GAP90365.1 - 7.5e-06 24.9 17.2 0.00034 19.4 17.0 2.9 2 1 0 2 2 2 1 Polycystin cation channel SnoaL PF07366.12 GAP90366.1 - 0.00018 21.3 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 GAP90366.1 - 0.0024 18.5 1.1 0.014 16.0 0.4 2.7 2 1 0 2 2 2 1 SnoaL-like domain Sugar_tr PF00083.24 GAP90367.1 - 1.9e-36 125.9 24.6 2.4e-35 122.3 24.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP90367.1 - 6.9e-32 110.7 46.0 3.8e-30 105.0 28.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 GAP90367.1 - 0.014 14.3 8.0 0.079 11.8 0.2 3.3 1 1 0 1 1 1 0 MFS_1 like family ATG22 PF11700.8 GAP90367.1 - 0.31 9.6 10.5 0.042 12.5 2.3 2.8 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like DUF5510 PF17629.2 GAP90367.1 - 4.2 7.4 6.7 9.2 6.3 0.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5510) Macro PF01661.21 GAP90368.1 - 6.3e-40 135.9 0.3 1e-39 135.2 0.3 1.4 1 0 0 1 1 1 1 Macro domain Sugar_tr PF00083.24 GAP90370.1 - 6e-49 167.1 31.5 7.3e-47 160.2 31.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP90370.1 - 6.3e-14 51.7 35.8 2.3e-11 43.3 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HPP PF04982.13 GAP90370.1 - 0.19 11.9 10.9 1.2 9.3 2.2 2.8 2 1 0 2 2 2 0 HPP family FAD_binding_3 PF01494.19 GAP90371.1 - 3.7e-07 29.7 0.1 7.1e-06 25.5 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP90371.1 - 0.0067 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 GAP90372.1 - 1.6e-23 83.2 0.2 1.9e-18 66.6 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP90372.1 - 2.1e-14 53.7 0.2 1.3e-13 51.1 0.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP90372.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 KR domain DUF1688 PF07958.11 GAP90373.1 - 0.013 14.2 0.0 0.015 14.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) MCR_alpha_N PF02745.15 GAP90373.1 - 0.034 13.5 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain CorA PF01544.18 GAP90374.1 - 1.1e-05 24.9 0.4 2.1e-05 24.0 0.4 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EMP70 PF02990.16 GAP90374.1 - 0.048 12.3 0.4 0.073 11.7 0.4 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Pkinase PF00069.25 GAP90375.1 - 1.6e-13 50.7 0.0 5e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 GAP90375.1 - 0.0072 15.9 0.1 0.049 13.2 0.0 2.4 2 1 0 2 2 2 1 Choline/ethanolamine kinase VWA_2 PF13519.6 GAP90375.1 - 0.028 15.0 0.1 0.16 12.6 0.0 2.4 3 0 0 3 3 3 0 von Willebrand factor type A domain DUF1386 PF07138.11 GAP90375.1 - 0.047 13.0 0.1 0.1 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1386) SIR2 PF02146.17 GAP90376.1 - 5.2e-32 111.2 0.0 2e-10 40.9 0.0 3.3 3 0 0 3 3 3 3 Sir2 family Zn-ribbon_8 PF09723.10 GAP90376.1 - 0.56 10.4 1.6 1.6 8.9 1.6 1.8 1 0 0 1 1 1 0 Zinc ribbon domain ABC_tran PF00005.27 GAP90377.1 - 2.3e-45 154.5 0.1 1.9e-23 83.5 0.0 3.4 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 GAP90377.1 - 5.4e-30 103.3 0.4 3.8e-29 100.5 0.1 2.5 2 0 0 2 2 2 1 Four helical bundle domain AAA_21 PF13304.6 GAP90377.1 - 2.4e-17 63.7 0.0 0.0014 18.6 0.0 5.1 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAP90377.1 - 1.4e-15 57.3 0.9 9.6e-05 21.9 0.1 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAP90377.1 - 1.4e-09 38.7 6.3 8.6e-05 23.1 0.3 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 GAP90377.1 - 9.7e-09 34.8 0.0 0.0055 16.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAP90377.1 - 1.4e-07 31.5 0.0 0.0012 18.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 GAP90377.1 - 1.7e-07 31.3 0.0 0.0022 18.0 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 GAP90377.1 - 8e-07 29.4 0.0 0.018 15.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 GAP90377.1 - 1.2e-06 28.8 0.1 0.028 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 GAP90377.1 - 1.4e-05 25.0 0.8 0.086 12.5 0.0 3.2 3 1 0 4 4 3 2 AAA ATPase domain AAA_18 PF13238.6 GAP90377.1 - 1.5e-05 25.5 0.0 0.17 12.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 GAP90377.1 - 1.6e-05 25.0 0.0 0.0016 18.6 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA PF00004.29 GAP90377.1 - 3.4e-05 24.3 0.0 0.6 10.5 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 GAP90377.1 - 5.1e-05 23.5 0.0 0.54 10.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 GAP90377.1 - 5.5e-05 23.6 0.1 0.39 11.1 0.0 3.3 4 0 0 4 4 3 2 AAA ATPase domain PduV-EutP PF10662.9 GAP90377.1 - 6.5e-05 22.7 0.1 0.057 13.2 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 GAP90377.1 - 0.00012 22.5 0.0 0.94 9.9 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_27 PF13514.6 GAP90377.1 - 0.00025 20.7 0.0 0.16 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 GAP90377.1 - 0.00025 20.1 0.8 0.78 8.7 0.0 2.8 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 GAP90377.1 - 0.00048 20.1 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain G-alpha PF00503.20 GAP90377.1 - 0.00058 19.1 0.1 0.62 9.2 0.0 2.7 3 0 0 3 3 2 2 G-protein alpha subunit DUF87 PF01935.17 GAP90377.1 - 0.00095 19.3 0.1 1 9.4 0.0 3.3 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_24 PF13479.6 GAP90377.1 - 0.0011 18.7 0.0 1.6 8.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 GAP90377.1 - 0.0012 18.8 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 GAP90377.1 - 0.0013 18.8 0.0 4.1 7.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 GAP90377.1 - 0.0014 18.3 0.0 2.8 7.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 GAP90377.1 - 0.0042 16.7 0.1 4.6 6.8 0.0 3.2 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 GAP90377.1 - 0.0043 17.3 0.0 9.3 6.5 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 GAP90377.1 - 0.0062 16.3 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 GAP90377.1 - 0.0064 15.8 0.5 2.4 7.3 0.0 3.2 3 0 0 3 3 3 1 Septin SbcCD_C PF13558.6 GAP90377.1 - 0.0068 16.6 0.0 1.5 9.1 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 GAP90377.1 - 0.0075 15.5 0.1 0.38 9.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Adaptin_N PF01602.20 GAP90377.1 - 0.0098 14.5 1.6 0.045 12.3 1.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region ATP_bind_1 PF03029.17 GAP90377.1 - 0.013 15.3 0.0 7.8 6.2 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 GAP90377.1 - 0.015 15.2 0.1 4.2 7.2 0.0 3.0 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea HEAT PF02985.22 GAP90377.1 - 0.016 15.5 0.2 64 4.2 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat CLP1_P PF16575.5 GAP90377.1 - 0.017 14.9 0.0 0.8 9.5 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 GAP90377.1 - 0.02 14.4 0.0 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DRIM PF07539.12 GAP90377.1 - 0.022 13.1 0.1 0.2 9.9 0.0 2.1 2 0 0 2 2 2 0 Down-regulated in metastasis AAA_13 PF13166.6 GAP90377.1 - 0.028 13.1 2.4 2.4 6.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain ATP-synt_ab PF00006.25 GAP90377.1 - 0.036 13.7 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 GAP90377.1 - 0.043 13.6 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 GAP90377.1 - 0.048 13.4 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 GAP90377.1 - 0.053 12.9 0.0 4.3 6.7 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 GAP90377.1 - 0.058 13.3 0.1 9.9 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 GAP90377.1 - 0.086 12.7 0.1 19 5.1 0.0 2.7 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.18 GAP90377.1 - 0.14 11.7 0.2 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ParcG PF10274.9 GAP90377.1 - 0.16 12.1 0.3 9.9 6.2 0.0 2.8 2 1 1 3 3 3 0 Parkin co-regulated protein Abhydrolase_1 PF00561.20 GAP90379.1 - 5.7e-16 58.9 0.0 2.8e-15 56.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP90379.1 - 2.6e-10 41.3 4.1 4.2e-10 40.6 4.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP90379.1 - 5.3e-10 39.0 0.0 7.7e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 GAP90379.1 - 6.4e-06 25.1 0.0 1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF3112 PF11309.8 GAP90380.1 - 2.7e-06 27.0 0.0 0.015 14.8 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) DUF2070 PF09843.9 GAP90380.1 - 2.1 6.5 11.2 2.7 6.2 11.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DotA PF11388.8 GAP90381.1 - 0.16 12.2 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Phagosome trafficking protein DotA DUF1996 PF09362.10 GAP90383.1 - 2.2e-82 276.5 1.2 2.8e-82 276.2 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) tRNA-synt_1c PF00749.21 GAP90384.1 - 6.5e-81 271.6 0.0 2.3e-52 177.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAP90384.1 - 3.1e-30 105.3 0.0 9.7e-30 103.7 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_60s PF00428.19 GAP90384.1 - 0.51 11.0 10.5 1.3 9.6 10.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Clr5 PF14420.6 GAP90385.1 - 1e-18 67.2 1.7 2.4e-18 66.1 1.7 1.7 1 0 0 1 1 1 1 Clr5 domain GST_N_3 PF13417.6 GAP90386.1 - 1.1e-14 54.6 0.0 2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAP90386.1 - 1.3e-14 54.3 0.0 2.8e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAP90386.1 - 1.7e-14 53.9 0.0 2.8e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 GAP90386.1 - 2.8e-05 24.3 0.0 5.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 GAP90386.1 - 0.00012 22.1 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAP90386.1 - 0.0044 17.2 0.0 0.01 16.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAM2 PF07145.15 GAP90387.1 - 0.0076 15.9 0.2 0.066 12.9 0.1 2.7 2 0 0 2 2 2 1 Ataxin-2 C-terminal region CAP_N PF01213.19 GAP90387.1 - 3.9 6.9 9.1 10 5.5 2.7 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal APH PF01636.23 GAP90388.1 - 6.2e-19 68.9 0.0 8.8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Got1 PF04178.12 GAP90389.1 - 1.2e-15 57.9 8.3 1.6e-15 57.5 8.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Profilin PF00235.19 GAP90390.1 - 1.5e-37 128.7 2.5 2.2e-25 89.4 0.5 2.1 2 0 0 2 2 2 2 Profilin Longin PF13774.6 GAP90392.1 - 6e-14 51.8 0.0 1.2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 GAP90392.1 - 9.3e-13 47.8 0.4 1.5e-12 47.2 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Herpes_UL36 PF03586.13 GAP90392.1 - 0.037 13.3 0.1 6.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein DUF16 PF01519.16 GAP90392.1 - 0.11 13.0 1.3 0.46 11.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Sec63 PF02889.16 GAP90393.1 - 9.2e-136 451.0 0.0 3.3e-79 265.7 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 GAP90393.1 - 1.3e-51 174.9 0.2 1.4e-27 96.6 0.2 3.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 GAP90393.1 - 8e-22 78.0 0.0 2.4e-10 40.7 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 GAP90393.1 - 1.3e-15 57.6 0.1 1.7e-06 28.3 0.0 4.3 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAP90393.1 - 4.7e-08 33.4 0.1 0.022 15.1 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 GAP90393.1 - 7.5e-07 29.1 0.1 0.011 15.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 GAP90393.1 - 2.9e-05 24.5 0.3 0.0055 17.0 0.3 2.7 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 GAP90393.1 - 0.00016 21.8 0.1 0.0009 19.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal helicase PWI domain T2SSE PF00437.20 GAP90393.1 - 0.062 12.4 0.0 3.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 GAP90393.1 - 0.15 11.8 0.3 14 5.3 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein TniB PF05621.11 GAP90393.1 - 0.18 11.2 1.8 21 4.4 0.1 3.7 4 0 0 4 4 4 0 Bacterial TniB protein GPI-anchored PF10342.9 GAP90394.1 - 7.4e-20 71.5 0.1 7.4e-20 71.5 0.1 2.8 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MFS_1 PF07690.16 GAP90395.1 - 8.2e-21 74.3 30.9 2.2e-19 69.6 15.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1275 PF06912.11 GAP90398.1 - 4.8e-41 140.8 16.9 5.6e-41 140.6 16.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DEAD PF00270.29 GAP90399.1 - 1.4e-18 67.3 0.0 2.8e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 GAP90399.1 - 1.1e-17 64.4 3.7 3.2e-17 63.0 3.7 1.9 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 GAP90399.1 - 1.2e-16 61.0 0.0 1.8e-14 54.0 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 GAP90399.1 - 1.5e-10 40.8 1.6 2.3e-10 40.3 0.4 1.9 2 0 0 2 2 2 1 RQC domain ResIII PF04851.15 GAP90399.1 - 1.8e-05 24.8 0.0 5.6e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CdiI_2 PF18593.1 GAP90399.1 - 0.092 13.4 0.0 0.63 10.7 0.0 2.5 2 0 0 2 2 2 0 CdiI immunity protein HRDC PF00570.23 GAP90399.1 - 0.1 12.6 0.0 0.59 10.2 0.0 2.2 2 0 0 2 2 2 0 HRDC domain KAR9 PF08580.10 GAP90400.1 - 7.8e-176 586.6 1.8 7.8e-176 586.6 1.8 1.8 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.11 GAP90400.1 - 0.016 15.7 4.0 0.5 10.9 0.2 3.9 4 0 0 4 4 4 0 Syntaxin 6, N-terminal PLU-1 PF08429.11 GAP90400.1 - 0.034 13.3 0.1 1.1 8.3 0.0 2.7 2 1 1 3 3 3 0 PLU-1-like protein CH PF00307.31 GAP90401.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Calponin homology (CH) domain Cas_APE2256 PF09651.10 GAP90401.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) AAA PF00004.29 GAP90402.1 - 5.5e-43 146.6 0.0 1.2e-42 145.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAP90402.1 - 3.2e-11 43.0 0.1 4.2e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAP90402.1 - 2.9e-09 36.6 1.4 4.4e-09 36.0 0.1 2.0 2 1 1 3 3 2 1 AAA+ lid domain AAA_16 PF13191.6 GAP90402.1 - 4.9e-08 33.5 0.1 6.7e-05 23.3 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 GAP90402.1 - 1.9e-06 27.9 0.1 3.8e-05 23.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAP90402.1 - 2.8e-06 27.6 0.0 9.2e-06 25.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 GAP90402.1 - 7.1e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAP90402.1 - 0.0002 21.6 0.1 0.006 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 GAP90402.1 - 0.00032 20.0 0.0 0.00076 18.7 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 GAP90402.1 - 0.00062 20.3 0.0 0.0025 18.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 GAP90402.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 GAP90402.1 - 0.0021 17.3 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 GAP90402.1 - 0.0036 16.7 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAP90402.1 - 0.0043 17.2 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 GAP90402.1 - 0.0048 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 GAP90402.1 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 GAP90402.1 - 0.0059 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 GAP90402.1 - 0.0076 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 GAP90402.1 - 0.0081 15.9 0.0 0.027 14.2 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 GAP90402.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 GAP90402.1 - 0.022 14.5 0.0 0.057 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 GAP90402.1 - 0.023 14.5 0.5 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 GAP90402.1 - 0.029 14.0 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_30 PF13604.6 GAP90402.1 - 0.036 13.8 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 GAP90402.1 - 0.044 13.5 0.1 3.8 7.2 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase NACHT PF05729.12 GAP90402.1 - 0.051 13.5 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 GAP90402.1 - 0.061 12.7 1.5 0.13 11.5 0.0 2.3 4 0 0 4 4 3 0 KaiC PhoH PF02562.16 GAP90402.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 GAP90402.1 - 0.072 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 GAP90402.1 - 0.075 11.7 3.2 3.6 6.1 2.3 2.2 2 0 0 2 2 2 0 AAA domain DHHA1 PF02272.19 GAP90402.1 - 0.076 13.4 4.4 0.18 12.2 0.9 2.9 3 1 0 3 3 3 0 DHHA1 domain eIF-1a PF01176.19 GAP90402.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 ATPase_2 PF01637.18 GAP90402.1 - 0.098 12.6 0.4 0.37 10.7 0.0 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 GAP90402.1 - 0.099 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAP90402.1 - 0.1 11.9 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 GAP90402.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SIS PF01380.22 GAP90403.1 - 9.5e-60 200.2 0.1 1.4e-31 109.0 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 GAP90403.1 - 3.1e-17 63.0 0.0 6.1e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAP90403.1 - 5.5e-10 39.2 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 GAP90403.1 - 0.0049 15.8 0.0 0.0081 15.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Proteasome PF00227.26 GAP90404.1 - 7.3e-22 77.8 0.0 1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Phosphonate-bd PF12974.7 GAP90404.1 - 0.028 14.0 0.0 0.072 12.7 0.0 1.6 1 1 1 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein HCNGP PF07818.13 GAP90405.1 - 5.1e-22 78.3 0.0 1e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein UTRA PF07702.13 GAP90406.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 UTRA domain Cohesin_HEAT PF12765.7 GAP90407.1 - 0.2 12.0 0.4 0.34 11.3 0.4 1.3 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion AAA PF00004.29 GAP90408.1 - 1.2e-18 67.8 0.0 2.8e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAP90408.1 - 4.1e-05 23.9 0.0 0.00013 22.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP90408.1 - 0.00016 22.1 1.1 0.0009 19.7 0.2 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GAP90408.1 - 0.0011 19.0 0.0 0.0036 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Hydin_ADK PF17213.3 GAP90408.1 - 0.0045 17.3 0.0 0.0045 17.3 0.0 3.0 3 1 0 3 3 3 1 Hydin Adenylate kinase-like domain NOA36 PF06524.12 GAP90408.1 - 0.0093 15.3 24.6 0.019 14.3 24.6 1.5 1 0 0 1 1 1 1 NOA36 protein AAA_18 PF13238.6 GAP90408.1 - 0.019 15.5 0.0 0.33 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain TFIIE_alpha PF02002.17 GAP90408.1 - 0.061 13.2 0.1 0.061 13.2 0.1 2.4 2 0 0 2 2 2 0 TFIIE alpha subunit Zeta_toxin PF06414.12 GAP90408.1 - 0.12 11.6 1.7 2.6 7.3 0.1 2.9 3 0 0 3 3 3 0 Zeta toxin RuvB_N PF05496.12 GAP90408.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Baculo_gp64 PF03273.13 GAP90409.1 - 0.013 14.4 0.9 0.018 13.9 0.9 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Ist1 PF03398.14 GAP90409.1 - 0.036 14.0 3.0 0.075 13.0 3.0 1.6 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway HSM3_N PF18795.1 GAP90409.1 - 0.11 12.0 0.1 0.23 10.8 0.1 1.7 1 1 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain MOSC PF03473.17 GAP90410.1 - 3.9e-34 117.5 0.0 6e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 GAP90410.1 - 6.6e-19 68.0 0.0 1.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 GAP90410.1 - 9.6e-17 61.0 0.0 2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V DUF554 PF04474.12 GAP90410.1 - 0.066 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF554) AAA_16 PF13191.6 GAP90411.1 - 1.6e-12 48.2 0.1 1e-11 45.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP90411.1 - 5.4e-12 46.2 0.0 1.8e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 GAP90411.1 - 2.1e-10 41.1 0.0 5.3e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 GAP90411.1 - 1.7e-06 28.4 0.0 9.4e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 GAP90411.1 - 2e-06 27.8 0.1 5.1e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_30 PF13604.6 GAP90411.1 - 3.9e-05 23.5 0.0 8.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 GAP90411.1 - 4.5e-05 23.3 0.3 0.0002 21.3 0.0 2.2 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain TniB PF05621.11 GAP90411.1 - 0.00065 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein Helicase_RecD PF05127.14 GAP90411.1 - 0.0015 18.4 0.4 0.018 14.9 0.0 2.5 2 1 1 3 3 3 1 Helicase AAA_7 PF12775.7 GAP90411.1 - 0.0018 17.8 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 GAP90411.1 - 0.0045 16.9 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 GAP90411.1 - 0.0057 16.7 0.0 0.017 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 GAP90411.1 - 0.0063 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KAP_NTPase PF07693.14 GAP90411.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.22 GAP90411.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 GAP90411.1 - 0.021 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 GAP90411.1 - 0.032 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 GAP90411.1 - 0.036 13.8 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAP90411.1 - 0.055 12.7 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 GAP90411.1 - 0.061 12.4 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.13 GAP90411.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.29 GAP90411.1 - 0.12 12.2 0.3 3.9 7.2 0.3 2.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase NB-ARC PF00931.22 GAP90411.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Arrestin_N PF00339.29 GAP90412.1 - 1.5e-14 54.2 0.0 1e-13 51.6 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAP90412.1 - 1.4e-07 32.1 0.0 9.1e-06 26.2 0.0 2.8 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 GAP90412.1 - 0.16 10.9 0.0 0.98 8.4 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 zf-RING_UBOX PF13445.6 GAP90413.1 - 0.00017 21.5 8.9 0.00024 21.1 1.3 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAP90413.1 - 0.003 17.9 4.0 0.003 17.9 4.0 3.5 2 2 1 3 3 3 1 Ring finger domain Ribosomal_60s PF00428.19 GAP90413.1 - 0.0038 17.8 5.3 0.0064 17.1 5.3 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein zf-rbx1 PF12678.7 GAP90413.1 - 0.027 14.8 0.7 0.027 14.8 0.7 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 GAP90413.1 - 0.048 13.5 0.0 0.048 13.5 0.0 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP90413.1 - 0.07 13.0 0.0 0.07 13.0 0.0 3.1 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAP90413.1 - 0.29 10.9 0.1 0.29 10.9 0.1 3.0 3 0 0 3 3 3 0 RING-like zinc finger Prok-RING_4 PF14447.6 GAP90413.1 - 0.72 9.8 0.0 0.72 9.8 0.0 3.7 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 GAP90413.1 - 1.3 9.3 9.5 2.5 8.3 1.5 3.4 3 1 0 3 3 3 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 GAP90413.1 - 1.8 8.5 13.2 5.1 7.0 0.0 4.4 4 1 1 5 5 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP90414.1 - 2.2e-09 37.5 4.4 5.3e-09 36.3 4.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 GAP90414.1 - 1.2e-07 31.5 4.0 3e-07 30.2 4.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP90414.1 - 1.7e-07 31.1 1.3 1.7e-07 31.1 1.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 GAP90414.1 - 2.5e-06 27.7 4.3 5.7e-06 26.5 4.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAP90414.1 - 5.9e-06 26.1 3.7 1.3e-05 25.1 3.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAP90414.1 - 8.3e-06 25.6 4.4 2e-05 24.3 4.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAP90414.1 - 2.6e-05 24.0 3.2 2.6e-05 24.0 3.2 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 GAP90414.1 - 4.6e-05 23.2 7.2 4.6e-05 23.2 7.2 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAP90414.1 - 0.00011 22.2 1.5 0.00035 20.7 1.5 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 GAP90414.1 - 0.0029 17.2 2.3 0.0091 15.6 2.3 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 GAP90414.1 - 0.026 14.6 2.1 0.049 13.7 2.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pellino PF04710.14 GAP90414.1 - 0.047 12.4 0.6 0.063 11.9 0.6 1.1 1 0 0 1 1 1 0 Pellino Rtf2 PF04641.12 GAP90414.1 - 0.43 9.9 0.6 0.71 9.2 0.6 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger ThiF PF00899.21 GAP90416.1 - 8.8e-55 185.7 0.0 1.3e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 GAP90416.1 - 2.4e-12 47.3 0.0 4.5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Prefoldin PF02996.17 GAP90416.1 - 0.17 11.8 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit GPS2_interact PF15784.5 GAP90416.1 - 0.18 12.3 0.2 0.31 11.5 0.2 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Shikimate_DH PF01488.20 GAP90416.1 - 0.21 11.7 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 GAP90416.1 - 0.26 10.5 1.4 0.38 10.0 1.4 1.2 1 0 0 1 1 1 0 FAD binding domain Pam17 PF08566.10 GAP90417.1 - 4.7e-57 192.4 0.0 5.6e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Mntp PF02659.15 GAP90417.1 - 0.023 14.5 0.2 0.032 14.0 0.2 1.2 1 0 0 1 1 1 0 Putative manganese efflux pump Ig_GlcNase PF18368.1 GAP90418.1 - 2.5e-33 114.4 0.3 2.5e-33 114.4 0.3 3.1 4 0 0 4 4 4 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 GAP90418.1 - 8.7e-14 52.1 0.7 8.7e-14 52.1 0.7 3.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 GAP90418.1 - 2.9e-07 31.0 7.1 1.6e-06 28.6 0.2 3.1 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_N PF02837.18 GAP90418.1 - 0.00019 21.4 0.3 0.00062 19.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 GAP90418.1 - 0.0014 18.4 0.9 0.0093 15.7 0.1 2.6 2 1 1 3 3 3 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 GAP90418.1 - 0.027 13.6 0.1 0.047 12.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Peptidase_C47 PF05543.13 GAP90418.1 - 0.08 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Staphopain peptidase C47 BNR_2 PF13088.6 GAP90419.1 - 5.5e-06 25.9 0.0 0.0064 15.8 0.0 2.6 1 1 2 3 3 3 2 BNR repeat-like domain BNR PF02012.20 GAP90419.1 - 0.0042 16.9 6.4 0.53 10.5 0.2 3.7 3 0 0 3 3 3 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 GAP90419.1 - 0.009 14.8 0.5 0.071 11.9 0.5 2.1 1 1 0 1 1 1 1 Sortilin, neurotensin receptor 3, SLATT_1 PF18181.1 GAP90420.1 - 3.4 7.6 6.1 2.8 7.9 2.6 2.5 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DivIC PF04977.15 GAP90421.1 - 0.66 9.8 3.5 1.6 8.5 0.8 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF4470 PF14737.6 GAP90422.1 - 6.9e-19 67.8 0.1 2.4e-18 66.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) RNase_H2_suC PF08615.11 GAP90423.1 - 1.8e-27 96.3 0.0 2.1e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Gamma_PGA_hydro PF05908.11 GAP90423.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase MOZ_SAS PF01853.18 GAP90424.1 - 6.3e-81 270.3 0.2 8.9e-81 269.8 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 GAP90424.1 - 1.8e-23 81.9 1.4 3.6e-23 80.9 1.4 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 GAP90424.1 - 9.4e-18 63.9 0.0 2.6e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 GAP90424.1 - 0.00092 19.6 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP90424.1 - 0.035 14.3 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Aminotran_1_2 PF00155.21 GAP90425.1 - 4.7e-11 42.5 0.0 6.8e-07 28.8 0.0 3.5 4 0 0 4 4 4 2 Aminotransferase class I and II Aminotran_MocR PF12897.7 GAP90425.1 - 0.012 14.5 0.0 0.033 13.0 0.0 1.6 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Glyco_hydro_125 PF06824.11 GAP90426.1 - 4.4e-179 595.7 0.0 5.3e-179 595.4 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Pantoate_ligase PF02569.15 GAP90427.1 - 1.2e-82 277.1 0.0 1.4e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DNA_photolyase PF00875.18 GAP90427.1 - 0.082 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 DNA photolyase SNF2_N PF00176.23 GAP90429.1 - 4e-63 213.3 0.2 9.1e-63 212.1 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP90429.1 - 5.2e-23 81.5 0.0 2e-22 79.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP90429.1 - 2.9e-08 33.9 0.0 9.4e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAP90429.1 - 3.4e-06 26.5 0.1 1.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 GAP90429.1 - 0.0015 18.2 0.0 0.0074 16.0 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF1117 PF06547.12 GAP90429.1 - 0.56 10.8 5.4 4 8.0 5.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) TFIIA PF03153.13 GAP90429.1 - 1.5 8.8 11.9 0.44 10.5 3.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AT_hook PF02178.19 GAP90429.1 - 8 6.7 7.6 0.75 9.9 1.9 2.5 2 0 0 2 2 2 0 AT hook motif Sld5 PF05916.11 GAP90430.1 - 1.4e-28 99.5 0.0 2.1e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein TcA_TcB_BD PF18276.1 GAP90431.1 - 6.2e-122 406.2 0.0 1.9e-121 404.6 0.0 1.7 2 0 0 2 2 2 1 Tc toxin complex TcA C-terminal TcB-binding domain Neuraminidase PF18413.1 GAP90432.1 - 1.2e-39 135.7 1.2 2.6e-39 134.6 1.2 1.6 1 0 0 1 1 1 1 Neuraminidase-like domain VRP1 PF03538.14 GAP90432.1 - 8.8e-06 25.3 0.0 3.5e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Salmonella virulence plasmid 28.1kDa A protein SpvB PF03534.13 GAP90434.1 - 1.6e-101 339.3 0.0 4.2e-101 338.0 0.0 1.8 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.8 GAP90434.1 - 1e-29 103.2 1.2 7.4e-24 84.1 0.0 5.3 4 1 1 5 5 5 2 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.8 GAP90434.1 - 3.9e-24 85.4 0.1 9.6e-24 84.1 0.1 1.7 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.6 GAP90434.1 - 4.6e-09 36.7 16.0 0.012 16.1 0.1 5.2 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF2380 PF09533.10 GAP90434.1 - 1.4e-08 34.6 0.0 3.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) RHS_repeat PF05593.14 GAP90434.1 - 3.5e-06 27.4 26.7 1.6 9.3 0.0 12.0 13 0 0 13 13 13 1 RHS Repeat Glyco_hydro2_C5 PF18565.1 GAP90435.1 - 1.8e-32 111.2 0.1 3.3e-32 110.4 0.1 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 GAP90435.1 - 1.5e-27 96.5 0.0 3.1e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 GAP90435.1 - 4.6e-22 77.7 0.1 1.6e-21 76.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 GAP90435.1 - 3.4e-19 69.4 0.0 1.1e-18 67.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 GAP90435.1 - 2e-14 54.2 0.2 5.2e-14 52.8 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 GAP90435.1 - 1.4e-05 25.6 0.2 0.00079 20.0 0.0 3.3 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 GAP90435.1 - 0.089 13.1 2.7 0.15 12.3 1.3 2.2 2 1 0 2 2 2 0 Invasin, domain 3 Aminotran_1_2 PF00155.21 GAP90436.1 - 1.7e-63 215.0 0.0 2.1e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II p450 PF00067.22 GAP90439.1 - 1.9e-65 221.4 0.0 2.6e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.23 GAP90442.1 - 7.7e-76 255.1 0.1 7e-75 251.9 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP90442.1 - 9.3e-13 48.5 0.0 4.5e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAP90442.1 - 2.6e-09 37.1 0.0 2.9e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 GAP90442.1 - 1.4e-07 31.7 0.0 2.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 GAP90442.1 - 0.0042 17.4 6.1 0.013 15.8 6.1 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 GAP90442.1 - 0.0043 16.9 5.0 0.014 15.2 5.0 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 GAP90442.1 - 0.0065 16.4 5.9 0.014 15.3 5.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 GAP90442.1 - 0.0083 16.0 7.0 0.029 14.2 7.1 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 GAP90442.1 - 0.038 13.9 5.2 0.12 12.2 5.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP90442.1 - 1.3 9.1 5.6 3.2 7.9 5.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zinc-ribbons_6 PF07191.12 GAP90442.1 - 3.1 7.9 7.0 3.4 7.7 5.4 1.9 2 0 0 2 2 2 0 zinc-ribbons zf-RING_4 PF14570.6 GAP90442.1 - 8.2 6.3 7.3 19 5.2 7.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NACHT PF05729.12 GAP90443.1 - 1.9e-06 27.9 0.0 4.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP90443.1 - 2.9e-05 24.5 0.1 0.00012 22.5 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP90443.1 - 0.00014 22.1 0.0 0.00092 19.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain Ank_4 PF13637.6 GAP90443.1 - 0.00041 20.9 0.0 0.027 15.0 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AAA PF00004.29 GAP90443.1 - 0.0019 18.6 0.0 0.0058 17.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_3 PF13606.6 GAP90443.1 - 0.17 12.5 0.1 6.4 7.7 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat Kinesin PF00225.23 GAP90444.1 - 1.2e-54 185.5 0.0 2.6e-54 184.4 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAP90444.1 - 3.2e-12 46.6 0.0 1.7e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding EzrA PF06160.12 GAP90444.1 - 0.011 13.9 0.3 0.02 13.1 0.3 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF5094 PF17015.5 GAP90444.1 - 0.015 15.4 0.7 0.027 14.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Jnk-SapK_ap_N PF09744.9 GAP90444.1 - 0.14 12.3 9.7 0.27 11.4 3.4 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 HALZ PF02183.18 GAP90444.1 - 0.18 12.1 1.2 0.37 11.1 1.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper SlyX PF04102.12 GAP90444.1 - 0.28 11.8 4.8 4.8 7.9 0.8 2.7 2 0 0 2 2 2 0 SlyX TMCO5 PF14992.6 GAP90444.1 - 0.31 10.6 3.2 0.6 9.6 3.2 1.4 1 0 0 1 1 1 0 TMCO5 family Glyco_hydro_7 PF00840.20 GAP90445.1 - 2.7e-159 530.5 15.6 3.3e-159 530.2 15.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Hamartin PF04388.12 GAP90446.1 - 8.2e-14 51.2 32.1 8.2e-14 51.2 32.1 3.4 1 1 0 2 2 2 1 Hamartin protein DJ-1_PfpI PF01965.24 GAP90447.1 - 2.8e-14 53.3 0.0 4.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAP90447.1 - 7.1e-05 22.6 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like Ribosomal_L23 PF00276.20 GAP90448.1 - 2.7e-10 40.5 0.0 6.6e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L23 MT-A70 PF05063.14 GAP90449.1 - 6.5e-32 110.8 0.1 9e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 MT-A70 RSN1_7TM PF02714.15 GAP90450.1 - 9.3e-82 274.4 26.2 1.3e-80 270.6 24.3 2.4 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 GAP90450.1 - 2.8e-44 150.6 0.1 2.8e-44 150.6 0.1 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 GAP90450.1 - 1.6e-27 96.9 4.5 1.9e-15 57.6 0.3 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 GAP90450.1 - 1.2e-15 57.4 0.0 3.6e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter ChpA-C PF03777.13 GAP90450.1 - 0.013 15.4 0.3 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 ChpA-C RR_TM4-6 PF06459.12 GAP90450.1 - 2.7 7.7 7.5 5.1 6.8 7.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3935 PF13071.6 GAP90450.1 - 6.6 7.3 9.0 9.3 6.9 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3935) EMP70 PF02990.16 GAP90451.1 - 1e-199 664.6 0.2 1.3e-199 664.2 0.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Mito_carr PF00153.27 GAP90452.1 - 1.9e-58 194.4 12.4 3.8e-20 71.6 0.1 4.3 4 1 0 4 4 4 3 Mitochondrial carrier protein Serine_protease PF18405.1 GAP90452.1 - 0.0079 15.4 6.0 0.19 10.8 0.0 3.2 3 1 0 3 3 3 2 Gammaproteobacterial serine protease Hamartin PF04388.12 GAP90452.1 - 5.3 5.6 4.5 8 5.0 4.5 1.2 1 0 0 1 1 1 0 Hamartin protein Ccdc124 PF06244.12 GAP90453.1 - 3e-12 47.2 17.4 3e-12 47.2 17.4 2.6 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HET PF06985.11 GAP90454.1 - 1.2e-28 100.3 0.0 7.6e-28 97.7 0.0 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DAGK_cat PF00781.24 GAP90455.1 - 2.5e-08 33.6 0.1 9e-08 31.8 0.1 1.9 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain ABC_tran PF00005.27 GAP90456.1 - 3e-45 154.1 0.9 3.3e-21 76.2 0.0 3.9 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 GAP90456.1 - 3.9e-12 46.6 4.3 0.00011 22.1 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAP90456.1 - 1.6e-09 37.4 0.4 5.3e-05 22.9 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 GAP90456.1 - 1.3e-08 34.6 1.7 0.033 13.6 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 GAP90456.1 - 6.8e-07 29.2 3.6 6.8e-07 29.2 3.6 2.3 2 0 0 2 2 1 1 ABC transporter MMR_HSR1 PF01926.23 GAP90456.1 - 1.4e-06 28.4 0.2 0.13 12.4 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_28 PF13521.6 GAP90456.1 - 2.5e-06 27.9 0.4 0.00071 19.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAP90456.1 - 1e-05 25.8 0.1 0.15 12.4 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_15 PF13175.6 GAP90456.1 - 2.3e-05 24.3 0.3 0.01 15.6 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 GAP90456.1 - 0.00014 21.8 0.6 0.0071 16.3 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 GAP90456.1 - 0.00029 21.4 14.3 0.043 14.3 3.0 3.6 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 GAP90456.1 - 0.00076 19.4 4.8 0.25 11.2 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 GAP90456.1 - 0.00098 19.7 0.2 0.81 10.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 GAP90456.1 - 0.0021 18.5 8.7 0.084 13.2 4.6 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 GAP90456.1 - 0.0021 17.8 12.3 0.22 11.2 0.1 4.2 4 1 1 5 5 5 2 AAA domain MeaB PF03308.16 GAP90456.1 - 0.0022 17.0 1.5 1 8.3 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 GAP90456.1 - 0.0028 17.8 5.7 0.52 10.5 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 GAP90456.1 - 0.0053 17.2 0.0 0.48 10.8 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 GAP90456.1 - 0.0087 16.1 2.9 0.3 11.1 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_14 PF13173.6 GAP90456.1 - 0.012 15.7 0.1 0.38 10.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 GAP90456.1 - 0.016 14.9 0.3 0.26 11.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 GAP90456.1 - 0.024 14.6 0.4 0.4 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 GAP90456.1 - 0.035 12.9 0.0 0.035 12.9 0.0 1.9 2 0 0 2 2 1 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 GAP90456.1 - 0.043 14.2 0.1 0.72 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 GAP90456.1 - 0.072 12.8 0.1 2.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 GAP90456.1 - 0.075 13.1 11.3 0.081 13.0 0.0 3.9 4 0 0 4 4 4 0 Helicase HerA, central domain DUF815 PF05673.13 GAP90456.1 - 0.086 12.0 4.0 0.55 9.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 GAP90456.1 - 0.1 12.1 1.1 1.6 8.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 GAP90456.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.5 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 GAP90456.1 - 0.13 11.9 0.8 7 6.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 GAP90456.1 - 0.14 11.7 0.2 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 GAP90456.1 - 0.21 11.6 0.7 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 GAP90456.1 - 0.38 9.9 2.4 0.33 10.1 0.0 2.1 3 0 0 3 3 3 0 G-protein alpha subunit NB-ARC PF00931.22 GAP90456.1 - 0.87 8.7 0.0 0.87 8.7 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 GAP90456.1 - 0.95 8.8 4.5 2.4 7.4 0.0 2.9 2 1 0 3 3 3 0 FtsK/SpoIIIE family AAA_13 PF13166.6 GAP90456.1 - 2.5 6.7 8.3 2.2 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 GAP90456.1 - 9.4 6.7 8.4 5.9 7.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain Sugar_tr PF00083.24 GAP90457.1 - 1.6e-116 389.8 27.6 2e-116 389.6 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP90457.1 - 4.1e-19 68.7 43.2 5.6e-18 65.0 34.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Syndecan PF01034.20 GAP90457.1 - 1.6 8.7 0.0 1.6 8.7 0.0 3.4 5 0 0 5 5 5 0 Syndecan domain Phage_holin_3_2 PF04550.12 GAP90457.1 - 9.2 6.9 8.5 1 10.0 2.3 2.6 2 1 1 3 3 3 0 Phage holin family 2 SUN PF03856.13 GAP90458.1 - 2.2e-72 243.5 6.6 2.2e-72 243.5 6.6 1.6 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) Trypan_PARP PF05887.11 GAP90458.1 - 0.014 15.4 4.7 0.18 11.8 4.6 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) GET2 PF08690.10 GAP90458.1 - 3.2 7.3 7.4 4.8 6.8 7.4 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Pectinesterase PF01095.19 GAP90459.1 - 5.7e-55 186.1 9.0 7.6e-55 185.7 9.0 1.0 1 0 0 1 1 1 1 Pectinesterase Phage_T4_Ndd PF06591.11 GAP90459.1 - 0.082 12.7 0.9 1.8 8.4 0.1 2.5 1 1 2 3 3 3 0 T4-like phage nuclear disruption protein (Ndd) PCI PF01399.27 GAP90460.1 - 0.0002 21.8 0.2 0.99 9.9 0.1 2.6 2 0 0 2 2 2 2 PCI domain TPR_2 PF07719.17 GAP90460.1 - 0.037 14.1 0.0 0.12 12.5 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Thiolase_N PF00108.23 GAP90461.1 - 2.2e-86 289.4 0.2 4e-86 288.6 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAP90461.1 - 1.1e-37 128.5 1.9 1.6e-37 127.9 0.5 2.0 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 GAP90461.1 - 0.00012 21.8 1.1 0.00051 19.7 1.1 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.26 GAP90462.1 - 6.6e-52 174.9 0.0 7.4e-52 174.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAP90462.1 - 0.0005 19.8 0.0 0.00055 19.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAP90462.1 - 0.078 13.3 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 GAP90463.1 - 7.6e-112 373.5 0.1 7.6e-112 373.5 0.1 2.1 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 GAP90463.1 - 5.9e-25 87.9 0.0 2.3e-24 86.0 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding POTRA_2 PF08479.11 GAP90463.1 - 0.18 11.7 1.4 0.62 9.9 0.4 2.5 2 0 0 2 2 2 0 POTRA domain, ShlB-type HAP1_N PF04849.13 GAP90463.1 - 2.5 7.2 54.2 0.24 10.6 18.9 3.7 3 1 0 3 3 3 0 HAP1 N-terminal conserved region CALCOCO1 PF07888.11 GAP90463.1 - 9 5.0 57.6 0.025 13.5 30.3 2.3 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like zf-C2H2 PF00096.26 GAP90464.1 - 0.046 14.2 30.3 1.6 9.3 0.6 7.4 7 0 0 7 7 7 0 Zinc finger, C2H2 type Choline_kinase PF01633.20 GAP90466.1 - 2.2e-52 177.7 0.0 2.1e-51 174.6 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 GAP90466.1 - 2.5e-06 27.6 0.0 6.6e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family CorA PF01544.18 GAP90467.1 - 1.2e-08 34.7 0.1 2.9e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Acetyltransf_1 PF00583.25 GAP90468.1 - 9.9e-10 38.7 0.0 2.6e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP90468.1 - 8.2e-09 35.8 0.0 1.6e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP90468.1 - 7.9e-08 32.2 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 GAP90468.1 - 9.9e-07 28.7 0.0 2.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAP90468.1 - 0.00041 21.0 0.0 0.00067 20.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAP90468.1 - 0.0027 17.8 0.0 0.0074 16.4 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 GAP90468.1 - 0.0048 17.0 0.1 0.017 15.2 0.1 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 GAP90468.1 - 0.088 12.5 0.1 0.19 11.4 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CFEM PF05730.11 GAP90470.1 - 0.0029 17.7 5.6 0.0051 16.9 5.6 1.4 1 0 0 1 1 1 1 CFEM domain PKD PF00801.20 GAP90470.1 - 0.018 14.9 0.4 0.039 13.8 0.4 1.5 1 0 0 1 1 1 0 PKD domain MutS_V PF00488.21 GAP90471.1 - 6e-45 153.6 0.1 9.4e-45 153.0 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAP90471.1 - 6.5e-19 68.9 0.0 1.6e-18 67.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain III MMgT PF10270.9 GAP90472.1 - 1.5e-37 127.9 0.0 1.8e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter HAD_2 PF13419.6 GAP90473.1 - 1.8e-24 86.8 0.0 2.6e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP90473.1 - 1.4e-13 51.6 0.0 8.3e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP90473.1 - 2.6e-05 24.2 0.0 6.9e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 GAP90473.1 - 0.00066 20.1 0.0 0.00096 19.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 GAP90473.1 - 0.0022 18.0 0.0 0.0072 16.4 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase zf-Tim10_DDP PF02953.15 GAP90474.1 - 0.4 10.4 6.3 5.9 6.6 0.9 2.8 3 0 0 3 3 3 0 Tim10/DDP family zinc finger Aldolase_II PF00596.21 GAP90475.1 - 3.2e-35 121.8 0.0 3.9e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.18 GAP90476.1 - 3e-165 549.5 17.0 3.7e-165 549.2 17.0 1.1 1 0 0 1 1 1 1 Calreticulin family Methyltransf_11 PF08241.12 GAP90477.1 - 6.2e-12 46.0 0.0 1.5e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP90477.1 - 1e-05 26.1 0.0 2.9e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP90477.1 - 0.02 14.8 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 GAP90477.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAP90477.1 - 0.097 13.4 0.0 0.23 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 GAP90477.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SUI1 PF01253.22 GAP90478.1 - 4.5e-27 94.4 0.2 4.5e-27 94.4 0.2 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 Img2 PF05046.14 GAP90478.1 - 0.0041 17.4 0.1 0.0089 16.3 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) RPN2_C PF18004.1 GAP90478.1 - 0.012 15.6 5.3 0.017 15.0 5.3 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain MscS_TM PF12794.7 GAP90478.1 - 0.94 8.3 2.4 1.1 8.0 2.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Nbl1_Borealin_N PF10444.9 GAP90479.1 - 3.9e-17 61.6 6.8 5.9e-17 61.0 6.8 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.6 GAP90480.1 - 2.1e-25 89.4 0.3 5.8e-25 88.0 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 GAP90480.1 - 1.4e-10 41.8 0.1 2e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 GAP90480.1 - 1.5e-09 38.0 0.0 2.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 GAP90480.1 - 0.0067 16.3 1.8 0.017 15.0 1.8 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif NOP19 PF10863.8 GAP90480.1 - 0.066 13.0 1.8 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Nucleolar protein 19 RNA_pol_Rpb4 PF03874.16 GAP90481.1 - 2e-26 92.7 3.9 2.7e-26 92.3 3.9 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spexin PF15171.6 GAP90481.1 - 0.078 13.2 0.3 0.16 12.2 0.1 1.6 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin SUIM_assoc PF16619.5 GAP90482.1 - 0.33 11.0 9.4 1.5 8.9 8.1 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 GAP90482.1 - 5.7 6.8 18.0 0.056 13.4 6.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SKG6 PF08693.10 GAP90482.1 - 6 6.4 5.1 19 4.8 5.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CPL PF08144.11 GAP90483.1 - 5.3e-34 117.6 0.0 4.6e-33 114.6 0.0 2.6 3 0 0 3 3 3 1 CPL (NUC119) domain IN_DBD_C PF00552.21 GAP90483.1 - 0.084 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Integrase DNA binding domain RWD PF05773.22 GAP90484.1 - 1.2e-22 80.4 0.1 2.5e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 GAP90484.1 - 1.5e-06 28.6 8.0 3.1e-06 27.6 8.0 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF2852 PF11014.8 GAP90484.1 - 0.016 15.3 2.0 0.026 14.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF1517 PF07466.11 GAP90484.1 - 0.026 14.6 1.4 0.036 14.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) FKBP_N PF01346.18 GAP90484.1 - 2.4 9.2 5.6 1.1 10.3 0.1 2.2 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TPR_19 PF14559.6 GAP90485.1 - 3.9e-12 46.5 11.5 0.00033 21.1 3.3 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAP90485.1 - 1e-11 44.9 9.2 2.9e-07 30.7 0.2 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAP90485.1 - 5.7e-10 39.2 16.2 0.073 13.9 0.0 5.6 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAP90485.1 - 1.1e-09 38.8 17.9 1.1e-05 26.0 5.1 4.4 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAP90485.1 - 1.1e-09 37.7 0.2 0.00073 19.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAP90485.1 - 2.3e-09 36.6 12.8 0.00047 20.1 0.2 5.8 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP90485.1 - 2e-08 33.7 1.2 0.036 14.1 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAP90485.1 - 2.8e-08 33.2 4.0 0.013 15.3 0.1 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 GAP90485.1 - 1.2e-05 25.0 8.7 0.043 13.7 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAP90485.1 - 0.00012 21.6 1.1 0.057 12.8 0.0 2.5 2 1 0 2 2 2 2 MalT-like TPR region SHNi-TPR PF10516.9 GAP90485.1 - 0.0013 18.1 0.0 0.075 12.5 0.0 2.8 2 0 0 2 2 2 1 SHNi-TPR ANAPC3 PF12895.7 GAP90485.1 - 0.0016 18.6 0.1 0.26 11.5 0.0 3.2 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 GAP90485.1 - 0.021 14.5 0.4 0.79 9.5 0.1 3.2 4 0 0 4 4 4 0 TPR repeat TPR_9 PF13371.6 GAP90485.1 - 0.047 13.8 4.6 2.5 8.3 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAP90485.1 - 0.055 14.1 4.2 81 4.2 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Cas_Cas02710 PF09670.10 GAP90485.1 - 0.061 12.1 0.1 0.1 11.4 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) TPR_17 PF13431.6 GAP90485.1 - 0.094 13.1 0.0 14 6.3 0.0 4.0 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAP90485.1 - 0.13 13.0 8.2 0.56 11.0 0.5 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat ChAPs PF09295.10 GAP90485.1 - 0.46 9.4 2.2 1.5 7.7 0.2 2.5 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) SprT-like PF10263.9 GAP90486.1 - 0.037 13.9 5.3 0.063 13.1 3.8 2.1 2 1 0 2 2 2 0 SprT-like family Duffy_binding PF05424.11 GAP90486.1 - 0.042 13.9 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Duffy binding domain UPF0506 PF11703.8 GAP90488.1 - 0.033 14.6 19.8 0.33 11.3 6.0 2.3 2 0 0 2 2 2 0 UPF0506 Dickkopf_N PF04706.12 GAP90488.1 - 3.6 8.2 19.3 0.098 13.2 6.4 2.5 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Formyl_trans_N PF00551.19 GAP90490.1 - 1.2e-36 126.1 0.2 1.6e-36 125.7 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 GAP90490.1 - 2.9e-10 39.7 0.0 8.3e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 GAP90490.1 - 0.00051 20.0 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain Rad51 PF08423.11 GAP90492.1 - 1.8e-126 420.6 0.0 2.2e-126 420.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 GAP90492.1 - 1.1e-09 38.1 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 GAP90492.1 - 7.3e-08 32.2 0.0 1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 GAP90492.1 - 5.5e-06 25.9 0.0 1.2e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 GAP90492.1 - 4.5e-05 24.0 0.1 0.0001 22.9 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DnaB_C PF03796.15 GAP90492.1 - 0.011 15.0 0.1 0.048 13.0 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 GAP90492.1 - 0.07 13.1 0.5 0.61 10.1 0.1 2.3 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain DUF4332 PF14229.6 GAP90492.1 - 0.085 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) PAXNEB PF05625.11 GAP90492.1 - 0.12 11.5 0.2 0.86 8.7 0.0 2.0 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.8 GAP90493.1 - 1e-122 410.5 0.1 1.4e-122 410.1 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Vps26 PF03643.15 GAP90494.1 - 5.6e-131 435.6 0.8 6.5e-131 435.3 0.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 GAP90494.1 - 0.00017 21.7 0.3 0.9 9.6 0.0 3.5 1 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 GAP90494.1 - 0.033 14.6 0.0 0.3 11.5 0.0 2.4 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain IL17R_D_N PF16742.5 GAP90494.1 - 0.061 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Ribosomal_L6 PF00347.23 GAP90495.1 - 1.6e-26 92.7 6.0 7e-14 52.3 2.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF4690 PF15756.5 GAP90496.1 - 0.016 15.8 2.0 0.017 15.7 0.2 1.9 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF4834 PF16118.5 GAP90496.1 - 0.034 15.1 0.0 5.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Glycophorin_A PF01102.18 GAP90496.1 - 0.15 12.3 0.2 0.57 10.4 0.0 2.0 2 0 0 2 2 2 0 Glycophorin A SARAF PF06682.12 GAP90496.1 - 0.33 10.6 10.7 0.054 13.2 4.8 1.9 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF202 PF02656.15 GAP90496.1 - 1.3 9.6 6.3 1.7 9.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Rieske PF00355.26 GAP90497.1 - 3.7e-10 39.6 0.0 6.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 GAP90497.1 - 2.3e-07 30.7 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain V-ATPase_H_N PF03224.14 GAP90498.1 - 3e-75 253.4 0.0 4.1e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 GAP90498.1 - 1.4e-36 125.2 0.0 4.7e-36 123.5 0.0 2.0 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_2 PF13646.6 GAP90498.1 - 0.014 15.8 0.9 0.28 11.6 0.0 3.3 3 1 0 3 3 3 0 HEAT repeats HEAT PF02985.22 GAP90498.1 - 0.029 14.6 0.0 0.63 10.5 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat RIX1 PF08167.12 GAP90498.1 - 0.057 13.2 2.7 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Fib_alpha PF08702.10 GAP90498.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HEAT_EZ PF13513.6 GAP90498.1 - 0.12 12.9 3.7 3 8.5 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat Aldedh PF00171.22 GAP90499.1 - 8.4e-138 459.7 0.4 9.6e-138 459.5 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family F-box PF00646.33 GAP90500.1 - 3.2e-07 30.0 1.3 6.5e-07 29.1 1.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAP90500.1 - 5.5e-05 23.0 0.3 0.00011 22.0 0.3 1.5 1 0 0 1 1 1 1 F-box-like His_Phos_2 PF00328.22 GAP90501.1 - 2e-11 43.9 0.0 2.4e-08 33.7 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 GAP90502.1 - 5e-24 84.9 40.2 5e-24 84.9 40.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP90502.1 - 2.8e-08 33.1 12.4 2.8e-08 33.1 12.4 3.0 3 1 0 4 4 4 1 Sugar (and other) transporter DUF697 PF05128.12 GAP90502.1 - 0.32 10.7 1.7 0.41 10.3 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF697) UCR_UQCRX_QCR9 PF05365.12 GAP90502.1 - 0.66 10.0 7.0 16 5.5 0.9 4.4 2 1 1 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like CFEM PF05730.11 GAP90503.1 - 2.3e-14 53.2 10.5 2.3e-14 53.2 10.5 1.6 2 0 0 2 2 2 1 CFEM domain MGC-24 PF05283.11 GAP90503.1 - 0.021 15.3 12.7 0.029 14.8 12.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Sporozoite_P67 PF05642.11 GAP90503.1 - 0.084 10.9 7.2 0.11 10.6 7.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.17 GAP90503.1 - 0.093 12.7 28.7 0.15 12.1 28.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF962 PF06127.11 GAP90506.1 - 1.2e-26 92.6 0.5 1.8e-26 92.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.17 GAP90507.1 - 3.6e-15 56.1 0.0 6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 GAP90507.1 - 6.9e-14 52.0 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 GAP90507.1 - 0.029 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 RNase_II_C_S1 PF18614.1 GAP90507.1 - 0.037 14.0 0.5 3.8 7.5 0.1 2.5 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain Radical_SAM PF04055.21 GAP90508.1 - 0.0011 19.4 0.0 0.0025 18.2 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily LAM_C PF12544.8 GAP90508.1 - 0.016 15.4 0.1 0.037 14.2 0.1 1.5 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Sortilin-Vps10 PF15902.5 GAP90511.1 - 2.8e-280 929.5 12.0 1.5e-144 482.2 0.8 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 GAP90511.1 - 6.7e-88 293.4 23.9 9e-45 153.1 13.1 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 GAP90511.1 - 1.3e-10 39.6 43.5 0.22 11.6 0.1 12.9 12 0 0 12 12 12 4 BNR/Asp-box repeat BNR_2 PF13088.6 GAP90511.1 - 1.2e-06 28.0 11.1 0.13 11.5 0.2 6.4 4 3 2 6 6 6 2 BNR repeat-like domain DUF2561 PF10812.8 GAP90511.1 - 0.021 14.9 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) PSII_BNR PF14870.6 GAP90511.1 - 0.055 12.7 8.3 0.53 9.5 0.4 4.5 5 0 0 5 5 5 0 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 GAP90511.1 - 0.18 11.9 13.0 6.7 7.1 0.0 6.7 8 0 0 8 8 8 0 BNR-Asp box repeat CHB_HEX_C PF03174.13 GAP90511.1 - 0.52 10.3 11.0 4.2 7.4 0.1 5.5 7 0 0 7 7 7 0 Chitobiase/beta-hexosaminidase C-terminal domain SnoaL_2 PF12680.7 GAP90512.1 - 0.0074 16.9 0.0 0.02 15.5 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 GAP90512.1 - 0.052 13.3 0.0 0.14 11.9 0.0 1.8 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase AA_permease PF00324.21 GAP90513.1 - 1.8e-144 481.9 40.2 2.2e-144 481.6 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP90513.1 - 3.3e-36 125.0 40.4 4.2e-36 124.7 40.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 GAP90513.1 - 0.057 12.2 0.4 0.18 10.6 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) Glyco_hydro_47 PF01532.20 GAP90514.1 - 1.3e-166 555.1 0.0 1.5e-166 554.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Autophagy_act_C PF03987.15 GAP90515.1 - 1.4e-14 54.4 1.4 2.4e-14 53.6 1.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.22 GAP90516.1 - 1.8e-08 34.1 0.0 7e-08 32.2 0.0 2.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAP90516.1 - 1.5e-05 24.5 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 GAP90516.1 - 0.0079 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Limkain b1 Ribosomal_60s PF00428.19 GAP90516.1 - 0.083 13.5 12.7 0.2 12.3 12.6 1.8 1 1 0 1 1 1 0 60s Acidic ribosomal protein RRM_occluded PF16842.5 GAP90516.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif WD40 PF00400.32 GAP90517.1 - 5.4e-16 58.7 7.7 0.0016 19.3 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP90517.1 - 2.1e-07 31.1 0.0 0.13 12.6 0.0 4.6 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAP90517.1 - 0.046 13.7 0.0 7.3 6.7 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 GAP90518.1 - 1.9e-27 96.6 0.1 3.5e-27 95.7 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP90518.1 - 2.2e-08 33.7 0.1 4.6e-07 29.3 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 GAP90518.1 - 0.18 10.5 0.0 9.9 4.7 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) BTB PF00651.31 GAP90519.1 - 0.17 12.2 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain ADH_zinc_N PF00107.26 GAP90520.1 - 9.4e-12 45.0 0.1 6.1e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP90520.1 - 7.9e-07 30.2 0.0 4.6e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Ferric_reduct PF01794.19 GAP90521.1 - 3e-25 88.8 9.5 3e-25 88.8 9.5 1.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAP90521.1 - 9.6e-17 61.5 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAP90521.1 - 3.1e-10 40.1 0.0 6.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 GAP90521.1 - 6.2e-06 26.8 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ctr PF04145.15 GAP90522.1 - 1.4e-35 123.1 3.3 1.8e-35 122.7 3.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Sensor PF13796.6 GAP90522.1 - 0.066 13.3 4.1 8.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Putative sensor AGP PF06376.12 GAP90522.1 - 0.13 12.1 3.0 0.3 11.0 3.0 1.6 1 0 0 1 1 1 0 Arabinogalactan peptide DUF3487 PF11990.8 GAP90522.1 - 0.5 10.3 4.1 5.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF1218 PF06749.12 GAP90522.1 - 1.1 9.9 8.1 0.18 12.3 1.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) tRNA-synt_1b PF00579.25 GAP90523.1 - 5.8e-56 190.0 0.0 8.5e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DsrD PF08679.11 GAP90523.1 - 0.59 10.4 3.8 3.5 8.0 0.0 3.1 3 0 0 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) PNGaseA PF12222.8 GAP90525.1 - 1.4e-154 515.2 0.0 1.7e-154 514.9 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A VIT_2 PF13757.6 GAP90525.1 - 0.0015 18.4 0.2 0.19 11.6 0.0 2.6 2 0 0 2 2 2 2 Vault protein inter-alpha-trypsin domain PBP PF01161.20 GAP90526.1 - 2.4e-09 37.6 0.2 3e-09 37.3 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SnoaL_3 PF13474.6 GAP90526.1 - 0.061 13.6 0.0 0.23 11.7 0.0 1.8 1 1 1 2 2 2 0 SnoaL-like domain YXWGXW PF12779.7 GAP90527.1 - 2.6 8.3 13.5 0.47 10.6 8.8 2.3 2 0 0 2 2 2 0 YXWGXW repeat (2 copies) Ytp1 PF10355.9 GAP90528.1 - 8.1e-68 228.6 19.5 2.9e-67 226.8 19.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 GAP90528.1 - 1.6e-31 108.2 1.0 1.6e-31 108.2 1.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3700 PF12481.8 GAP90528.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Aluminium induced protein Dynactin_p22 PF07426.11 GAP90529.1 - 1.8 8.4 7.2 28 4.5 0.3 3.5 3 1 0 3 3 3 0 Dynactin subunit p22 DNA_pol_phi PF04931.13 GAP90529.1 - 3.5 5.6 11.0 9.4 4.2 11.0 1.6 1 0 0 1 1 1 0 DNA polymerase phi DUF3990 PF13151.6 GAP90531.1 - 0.00021 21.0 0.1 0.00032 20.4 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3990) TruB_N PF01509.18 GAP90532.1 - 1.4e-45 155.3 0.3 2.8e-45 154.4 0.0 1.6 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GAP90532.1 - 5.3e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DUF4048 PF13257.6 GAP90533.1 - 3.3e-18 66.5 6.0 4.1e-17 62.9 0.6 4.2 1 1 3 4 4 4 2 Domain of unknown function (DUF4048) SlyX PF04102.12 GAP90533.1 - 0.1 13.2 0.1 0.39 11.4 0.1 2.0 1 0 0 1 1 1 0 SlyX DNA_ligase_A_M PF01068.21 GAP90534.1 - 2.2e-26 92.8 0.0 5.1e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 GAP90534.1 - 3.6e-16 60.0 0.0 2.4e-15 57.3 0.0 2.3 3 0 0 3 3 3 1 DNA ligase N terminus RNA_ligase PF09414.10 GAP90534.1 - 7e-06 26.4 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 RNA ligase ERG2_Sigma1R PF04622.12 GAP90535.1 - 4.4e-97 323.5 0.3 5.2e-97 323.2 0.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein EXOSC1 PF10447.9 GAP90536.1 - 2.3e-21 76.4 3.5 4.1e-14 53.1 0.3 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 GAP90536.1 - 5.5e-11 42.1 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.23 GAP90536.1 - 0.018 15.3 0.5 0.1 13.0 0.5 2.0 1 1 0 1 1 1 0 S1 RNA binding domain SlyX PF04102.12 GAP90537.1 - 0.012 16.2 0.9 0.019 15.6 0.9 1.4 1 0 0 1 1 1 0 SlyX Mito_fiss_reg PF05308.11 GAP90537.1 - 0.54 10.3 0.1 0.54 10.3 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial fission regulator FSA_C PF10479.9 GAP90537.1 - 4.7 5.2 6.2 4.7 5.2 6.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sec2p PF06428.11 GAP90538.1 - 1.2e-13 50.9 1.3 2e-13 50.1 1.3 1.4 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p MbeD_MobD PF04899.12 GAP90538.1 - 0.023 14.8 2.4 0.43 10.7 2.4 2.6 1 1 0 1 1 1 0 MbeD/MobD like ATP-synt_ab PF00006.25 GAP90539.1 - 1.4e-108 361.4 0.0 2e-108 360.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 GAP90539.1 - 8.5e-49 164.4 0.1 1.6e-48 163.6 0.1 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 GAP90539.1 - 1.9e-13 50.7 2.3 4.8e-13 49.4 2.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LcrG PF07216.12 GAP90539.1 - 0.085 12.8 0.0 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 LcrG protein Metallophos PF00149.28 GAP90540.1 - 1.8e-14 54.7 0.2 2.9e-14 54.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ACT_7 PF13840.6 GAP90541.1 - 2.9e-23 81.4 0.4 1.4e-17 63.2 0.1 2.3 2 0 0 2 2 2 2 ACT domain Methyltransf_32 PF13679.6 GAP90542.1 - 7e-21 74.9 0.0 4e-20 72.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.11 GAP90543.1 - 1.5e-24 86.4 0.0 6.7e-24 84.3 0.0 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 GAP90543.1 - 0.00021 21.2 1.0 0.00039 20.4 0.2 1.9 2 0 0 2 2 2 1 SNARE domain Pox_EPC_I2-L1 PF12575.8 GAP90543.1 - 0.04 14.1 0.3 17 5.7 0.0 3.0 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 GCIP PF13324.6 GAP90543.1 - 0.35 10.4 2.5 0.67 9.5 2.5 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RRN3 PF05327.11 GAP90543.1 - 1.3 7.5 5.5 1.8 7.0 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DegS PF05384.11 GAP90543.1 - 6.5 6.2 6.7 8.1 5.9 4.0 2.4 3 1 0 3 3 3 0 Sensor protein DegS GLE1 PF07817.13 GAP90544.1 - 5.7e-59 199.3 0.0 7.5e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 GLE1-like protein Kinesin_assoc PF16183.5 GAP90544.1 - 0.05 13.7 2.8 0.14 12.3 2.8 1.7 1 0 0 1 1 1 0 Kinesin-associated Macoilin PF09726.9 GAP90544.1 - 1.7 7.1 16.1 0.43 9.1 1.1 2.1 2 0 0 2 2 2 0 Macoilin family DivIC PF04977.15 GAP90544.1 - 5.9 6.7 7.6 1.1e+02 2.7 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator COesterase PF00135.28 GAP90545.1 - 1.2e-77 262.0 3.9 3e-77 260.7 3.9 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP90545.1 - 1.2e-05 25.2 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP90545.1 - 0.0029 17.1 0.4 0.0029 17.1 0.4 1.9 2 1 0 2 2 2 1 Prolyl oligopeptidase family ubiquitin PF00240.23 GAP90547.1 - 1.4e-20 72.8 0.1 9e-19 67.0 0.0 3.8 5 0 0 5 5 5 1 Ubiquitin family Rad60-SLD PF11976.8 GAP90547.1 - 3.6e-08 33.1 0.0 3.6e-06 26.7 0.0 3.6 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like DUF676 PF05057.14 GAP90547.1 - 6.6e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ubiquitin_2 PF14560.6 GAP90547.1 - 0.0005 20.5 0.1 0.0042 17.5 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin-like domain Abhydrolase_6 PF12697.7 GAP90547.1 - 0.0089 16.7 0.0 0.099 13.2 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAP90547.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Voldacs PF03517.13 GAP90547.1 - 0.05 13.7 0.7 0.13 12.4 0.7 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Hydrolase_4 PF12146.8 GAP90547.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ubiquitin_5 PF18037.1 GAP90547.1 - 0.22 11.9 0.1 0.71 10.3 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4611 PF15387.6 GAP90547.1 - 0.99 9.7 7.9 2.4 8.4 7.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RNB PF00773.19 GAP90548.1 - 2e-78 264.0 0.0 3.2e-78 263.4 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 GAP90548.1 - 5.2e-26 90.5 0.0 1.3e-25 89.2 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 GAP90548.1 - 2.5e-25 88.6 0.0 7.1e-25 87.2 0.0 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 GAP90548.1 - 7.4e-07 29.3 0.0 0.0024 18.0 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 GAP90548.1 - 0.025 14.3 0.8 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 Rrp44-like cold shock domain TFIIA PF03153.13 GAP90548.1 - 0.96 9.4 36.4 0.78 9.7 9.0 3.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Ferritin_2 PF13668.6 GAP90549.1 - 4.2e-40 137.1 0.3 6.3e-40 136.5 0.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain SAP PF02037.27 GAP90550.1 - 1.9e-13 49.8 0.1 3.2e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 GAP90550.1 - 1.4e-05 24.8 1.0 1.4e-05 24.8 1.0 2.4 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain HeH PF12949.7 GAP90550.1 - 0.0044 16.7 0.3 0.0091 15.7 0.3 1.5 1 0 0 1 1 1 1 HeH/LEM domain eIF-3_zeta PF05091.12 GAP90550.1 - 2.4 7.1 5.9 3.2 6.6 5.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FANC_SAP PF18081.1 GAP90550.1 - 4.7 7.5 7.4 0.34 11.1 0.7 2.3 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Pkinase PF00069.25 GAP90551.1 - 2.6e-18 66.4 0.0 3.5e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP90551.1 - 8.6e-09 35.0 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP90551.1 - 3.5e-05 23.9 0.1 0.00015 21.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 GAP90551.1 - 7.9e-05 22.1 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 GAP90551.1 - 0.0017 18.0 0.1 0.0031 17.1 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 GAP90551.1 - 0.031 13.9 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Herpes_UL1 PF05259.11 GAP90551.1 - 0.094 12.8 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 Herpesvirus glycoprotein L DUF2922 PF11148.8 GAP90551.1 - 0.15 11.8 0.1 0.45 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) DUF2306 PF10067.9 GAP90552.1 - 3.7e-16 59.7 11.7 3.7e-16 59.7 11.7 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) p450 PF00067.22 GAP90553.1 - 2.8e-71 240.7 0.0 3.4e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 GAP90554.1 - 4.4e-51 169.7 14.3 1.3e-07 32.2 0.0 8.4 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP90554.1 - 3.5e-08 33.6 0.0 0.15 12.4 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP90554.1 - 2e-05 23.5 4.2 0.017 13.8 0.0 4.5 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAP90554.1 - 0.012 14.3 0.0 3.3 6.3 0.0 2.9 2 1 1 3 3 3 0 Nup133 N terminal like FAD_binding_4 PF01565.23 GAP90556.1 - 8.2e-29 100.1 0.0 1.4e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 GAP90556.1 - 1.5e-09 37.9 0.0 5.2e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain ECH_1 PF00378.20 GAP90557.1 - 8.7e-21 74.4 0.0 1.1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 GAP90557.1 - 5.7e-08 32.6 0.0 7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 GAP90557.1 - 0.13 12.2 0.0 22 5.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 DUF5100 PF17029.5 GAP90558.1 - 0.44 10.4 1.9 5.7 6.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5100) BOFC_N PF08977.10 GAP90558.1 - 1.6 8.8 4.7 18 5.4 0.1 3.2 3 0 0 3 3 3 0 Bypass of Forespore C, N terminal BRE1 PF08647.11 GAP90558.1 - 7.3 6.7 10.5 0.24 11.5 0.2 2.7 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Lac_bphage_repr PF06543.12 GAP90559.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor C6 PF01681.17 GAP90559.1 - 0.23 12.0 3.3 0.63 10.6 3.3 1.7 1 0 0 1 1 1 0 C6 domain Ras PF00071.22 GAP90561.1 - 9.9e-23 80.5 0.0 6.1e-21 74.7 0.0 2.1 1 1 1 2 2 2 1 Ras family Roc PF08477.13 GAP90561.1 - 7.6e-15 55.2 0.0 3.7e-13 49.7 0.0 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP90561.1 - 0.00015 21.3 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 GAP90561.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 GAP90561.1 - 0.0039 17.3 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TniB PF05621.11 GAP90561.1 - 0.2 11.0 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein GST_N PF02798.20 GAP90562.1 - 4.2e-14 52.7 0.0 6.7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP90562.1 - 7.9e-12 45.2 0.0 1.8e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAP90562.1 - 1e-11 45.1 0.0 1.7e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAP90562.1 - 5.3e-10 39.4 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAP90562.1 - 6.7e-09 35.9 0.0 1.4e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP90562.1 - 1e-08 35.1 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3720 PF12517.8 GAP90563.1 - 0.078 13.9 3.1 0.17 12.8 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Death PF00531.22 GAP90563.1 - 0.14 12.3 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Death domain K-box PF01486.17 GAP90564.1 - 0.078 13.2 0.6 0.2 11.8 0.6 1.6 1 0 0 1 1 1 0 K-box region UQ_con PF00179.26 GAP90565.1 - 5.2e-49 165.5 0.0 7.6e-49 165.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MS_channel PF00924.18 GAP90568.1 - 1.9e-22 79.9 2.0 3.6e-22 78.9 2.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 GAP90568.1 - 0.026 14.0 0.1 0.078 12.5 0.1 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 GAP90568.1 - 0.028 14.4 0.0 0.38 10.8 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain DUF2985 PF11204.8 GAP90568.1 - 0.041 14.0 0.6 0.62 10.3 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) EF-hand_1 PF00036.32 GAP90568.1 - 0.056 13.0 0.6 0.14 11.7 0.6 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 GAP90568.1 - 0.18 12.3 0.2 2.5 8.6 0.1 2.6 2 1 1 3 3 3 0 EF-hand domain pair E1-E2_ATPase PF00122.20 GAP90568.1 - 0.43 10.1 5.1 1.2 8.6 0.7 2.6 2 0 0 2 2 2 0 E1-E2 ATPase SAC3_GANP PF03399.16 GAP90569.1 - 2.3e-83 280.0 0.0 3.3e-83 279.5 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GAP90569.1 - 2e-05 24.6 0.0 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Phage_Mu_F PF04233.14 GAP90569.1 - 0.037 14.8 1.2 0.18 12.5 1.2 2.2 1 0 0 1 1 1 0 Phage Mu protein F like protein NMO PF03060.15 GAP90571.1 - 3.1e-50 171.4 1.0 4.6e-50 170.9 1.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAP90571.1 - 3.8e-09 36.0 1.0 8e-08 31.7 1.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAP90571.1 - 0.23 10.4 5.8 0.42 9.6 5.8 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Cupin_1 PF00190.22 GAP90574.1 - 3e-38 130.8 0.0 2.6e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 GAP90574.1 - 8.6e-25 86.3 0.5 1.7e-12 46.8 0.1 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 GAP90574.1 - 6.6e-10 38.6 0.1 0.00022 20.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 GAP90574.1 - 7.6e-07 29.1 0.0 1.5e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 GAP90574.1 - 3.1e-05 23.9 0.0 0.00096 19.1 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase DUF1971 PF09313.11 GAP90574.1 - 0.013 15.5 0.0 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) 3-HAO PF06052.12 GAP90574.1 - 0.013 15.1 0.0 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.12 GAP90574.1 - 0.039 13.4 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein PI-PLC-X PF00388.19 GAP90575.1 - 1.2e-57 193.6 0.0 2.2e-57 192.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 GAP90575.1 - 1.3e-42 144.8 0.4 3.7e-42 143.3 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain PH PF00169.29 GAP90575.1 - 0.00097 19.6 0.1 0.0023 18.4 0.1 1.7 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 GAP90575.1 - 0.0015 18.9 0.2 0.0066 16.9 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 GAP90575.1 - 0.052 13.1 0.1 0.35 10.5 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 GAP90575.1 - 0.083 12.9 0.1 1.8 8.7 0.1 3.0 1 1 1 2 2 2 0 EF-hand domain Egg_lysin PF01303.17 GAP90575.1 - 0.12 12.6 0.8 0.25 11.5 0.2 1.8 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) EF-hand_like PF09279.11 GAP90575.1 - 0.13 12.7 0.0 1.2 9.7 0.0 2.3 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like PH_12 PF16457.5 GAP90575.1 - 0.17 12.4 0.4 0.68 10.5 0.1 2.2 2 1 0 2 2 2 0 Pleckstrin homology domain DHHC PF01529.20 GAP90576.1 - 4.7e-39 133.6 9.2 9.2e-39 132.6 9.2 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase STELLO PF03385.17 GAP90576.1 - 0.15 10.8 0.1 0.22 10.3 0.1 1.1 1 0 0 1 1 1 0 STELLO glycosyltransferases Epimerase PF01370.21 GAP90577.1 - 2.1e-09 37.2 0.1 4.3e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP90577.1 - 5.7e-06 26.4 0.3 0.00012 22.0 0.3 2.1 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAP90577.1 - 9.3e-06 24.8 0.0 0.034 13.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 GAP90577.1 - 4.2e-05 22.8 0.0 6.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 GAP90577.1 - 0.0005 20.3 0.3 0.001 19.3 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 GAP90577.1 - 0.00053 19.6 0.1 0.00084 19.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 GAP90577.1 - 0.0066 17.0 0.0 0.21 12.2 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent zf-C2H2_4 PF13894.6 GAP90578.1 - 5.3e-11 42.4 20.1 0.08 13.8 0.3 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.26 GAP90578.1 - 9.5e-09 35.2 19.2 0.0045 17.4 0.8 5.6 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 GAP90578.1 - 1.8e-07 31.0 11.1 0.0009 19.2 1.0 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAP90578.1 - 8.6e-06 26.0 8.9 0.039 14.3 0.0 4.2 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 GAP90578.1 - 0.00098 19.4 2.9 0.031 14.6 0.1 3.0 2 1 0 2 2 2 1 C2H2-type zinc ribbon zf-CCHC_6 PF15288.6 GAP90578.1 - 0.012 15.4 0.6 0.08 12.8 0.0 2.7 2 0 0 2 2 2 0 Zinc knuckle zf_C2H2_10 PF18414.1 GAP90578.1 - 0.015 14.9 1.3 0.015 14.9 1.3 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger Integrase_DNA PF02920.15 GAP90578.1 - 0.026 14.2 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase zf_C2H2_ZHX PF18387.1 GAP90578.1 - 0.05 13.3 3.3 1.8 8.3 0.5 2.8 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain OrfB_Zn_ribbon PF07282.11 GAP90578.1 - 0.14 12.1 2.3 4.6 7.2 0.2 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-C2H2_3rep PF18868.1 GAP90578.1 - 0.18 12.5 9.6 0.27 11.9 1.2 3.7 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 GAP90578.1 - 0.21 11.9 4.7 55 4.2 0.4 4.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP90578.1 - 2.4 8.7 9.9 18 5.9 0.2 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 GAP90578.1 - 5.1 6.8 11.2 4.1 7.1 0.1 3.7 4 0 0 4 4 3 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 GAP90578.1 - 6.5 7.4 26.0 7.6 7.2 0.1 5.7 5 0 0 5 5 5 0 Zinc-finger double domain ADK_lid PF05191.14 GAP90578.1 - 8.8 6.4 9.4 0.47 10.5 2.3 2.8 3 0 0 3 3 2 0 Adenylate kinase, active site lid UQ_con PF00179.26 GAP90579.1 - 3.6e-18 65.5 0.0 5.5e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAP90579.1 - 0.039 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B IPPT PF01715.17 GAP90580.1 - 1.7e-60 204.7 0.0 9.4e-60 202.2 0.0 1.9 1 1 1 2 2 2 1 IPP transferase zf-C2H2_jaz PF12171.8 GAP90580.1 - 2.6e-06 27.5 0.3 5.4e-06 26.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP90580.1 - 7e-06 26.3 0.2 1.5e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_28 PF13521.6 GAP90580.1 - 0.00022 21.5 0.4 0.062 13.5 0.0 3.1 3 2 0 3 3 3 1 AAA domain IPT PF01745.16 GAP90580.1 - 0.00051 19.5 0.0 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 Isopentenyl transferase AAA_18 PF13238.6 GAP90580.1 - 0.0047 17.5 0.1 0.13 12.8 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 GAP90580.1 - 0.008 16.3 0.0 0.11 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAP90580.1 - 0.011 16.2 0.0 0.1 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain CTU2 PF10288.9 GAP90580.1 - 0.039 14.2 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Cytidylate_kin PF02224.18 GAP90580.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase PhoH PF02562.16 GAP90580.1 - 0.052 13.0 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 GAP90580.1 - 0.06 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 GAP90580.1 - 0.06 13.9 0.0 0.41 11.2 0.0 2.4 3 1 0 3 3 3 0 ABC transporter IstB_IS21 PF01695.17 GAP90580.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF87 PF01935.17 GAP90580.1 - 0.53 10.3 1.9 0.63 10.1 0.1 2.0 2 1 0 2 2 2 0 Helicase HerA, central domain AhpC-TSA PF00578.21 GAP90581.1 - 7e-37 126.1 0.0 9.4e-37 125.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAP90581.1 - 1.8e-13 50.5 0.0 2.3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 GAP90581.1 - 7.1e-12 45.0 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SecY PF00344.20 GAP90582.1 - 4.4e-70 236.3 7.5 5.7e-70 236.0 7.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 GAP90582.1 - 1.1e-17 63.5 0.3 3.2e-17 62.1 0.3 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Thioesterase PF00975.20 GAP90583.1 - 2.2e-17 63.9 0.0 2.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 GAP90583.1 - 0.0057 17.3 0.1 0.0063 17.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.25 GAP90584.1 - 3e-28 98.6 0.0 3.9e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP90584.1 - 7.8e-17 61.6 0.0 9.2e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP90584.1 - 5e-06 26.6 0.3 1.6e-05 24.9 0.3 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP90584.1 - 0.001 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 GAP90584.1 - 0.003 18.1 0.1 0.015 15.8 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 GAP90584.1 - 0.042 13.2 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.20 GAP90584.1 - 0.067 13.2 0.1 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 GAP90584.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PS-DH PF14765.6 GAP90585.1 - 1.3e-13 50.9 0.0 9.3e-09 34.9 0.0 2.4 1 1 1 2 2 2 2 Polyketide synthase dehydratase KR PF08659.10 GAP90585.1 - 1.2e-08 35.1 0.2 2.4e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 GAP90585.1 - 7.8e-06 27.0 0.0 1.9e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase BBE PF08031.12 GAP90586.1 - 1e-08 35.1 0.0 2.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like ABC_tran PF00005.27 GAP90587.1 - 2.9e-53 180.1 0.0 1.3e-30 106.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 GAP90587.1 - 5.1e-47 160.8 28.1 3.3e-30 105.7 8.7 2.8 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 GAP90587.1 - 1.3e-08 34.6 2.3 0.0035 16.8 0.3 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAP90587.1 - 3.3e-08 34.3 0.7 0.00022 21.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 GAP90587.1 - 3e-05 23.7 1.0 0.27 11.0 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 GAP90587.1 - 5.9e-05 23.1 0.0 0.034 14.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP90587.1 - 0.00014 21.8 0.1 0.8 9.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 GAP90587.1 - 0.00022 21.7 0.0 0.76 10.1 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 GAP90587.1 - 0.00022 21.1 0.4 3 7.6 0.0 3.6 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 GAP90587.1 - 0.00055 19.1 0.5 0.025 13.6 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 GAP90587.1 - 0.001 19.2 0.8 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain DEAD PF00270.29 GAP90587.1 - 0.0045 16.8 0.1 1.3 8.8 0.0 3.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 GAP90587.1 - 0.0065 16.7 0.1 19 5.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 GAP90587.1 - 0.0069 16.0 0.2 0.17 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 GAP90587.1 - 0.0076 16.3 0.0 2.3 8.2 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 GAP90587.1 - 0.011 15.0 0.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 GAP90587.1 - 0.02 14.4 0.3 3.7 7.0 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 GAP90587.1 - 0.028 14.8 0.3 6 7.3 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 GAP90587.1 - 0.032 14.0 0.2 4.2 7.1 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 GAP90587.1 - 0.036 13.8 2.5 6.7 6.4 0.1 3.4 4 0 0 4 4 4 0 AAA domain TrwB_AAD_bind PF10412.9 GAP90587.1 - 0.042 12.8 3.2 1.5 7.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 GAP90587.1 - 0.05 13.0 0.0 0.6 9.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 GAP90587.1 - 0.14 12.5 0.2 46 4.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_15 PF13175.6 GAP90587.1 - 0.16 11.6 1.3 1.5 8.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain CbiA PF01656.23 GAP90587.1 - 0.45 10.6 1.5 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SnoaL_2 PF12680.7 GAP90589.1 - 0.00054 20.6 2.6 0.00095 19.8 2.3 1.5 1 1 0 1 1 1 1 SnoaL-like domain Abhydrolase_1 PF00561.20 GAP90590.1 - 8.5e-13 48.5 0.2 7e-11 42.2 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP90590.1 - 3.3e-12 47.5 4.6 3.8e-12 47.3 4.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP90590.1 - 5.3e-09 35.7 0.0 1.4e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 KR PF08659.10 GAP90591.1 - 1.6e-21 77.0 1.9 2.3e-21 76.5 0.1 2.0 2 0 0 2 2 2 1 KR domain PP-binding PF00550.25 GAP90591.1 - 2.5e-05 24.5 0.0 4.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 GAP90592.1 - 5.2e-16 59.2 0.0 1.1e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 GAP90592.1 - 3.5e-13 49.7 0.0 7.6e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 GAP90592.1 - 1e-09 38.9 0.0 3.3e-09 37.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 GAP90592.1 - 6.7e-09 36.9 0.0 6.3e-08 33.8 0.0 2.6 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 GAP90592.1 - 6.8e-09 36.3 0.0 1.9e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP90592.1 - 2.1e-08 34.1 0.0 4.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP90592.1 - 2.1e-07 31.0 0.0 4.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP90592.1 - 1.9e-05 24.1 0.0 7.9e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family p450 PF00067.22 GAP90593.1 - 2e-44 152.1 0.0 2.5e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SAM_decarbox PF01536.16 GAP90594.1 - 9.7e-135 449.1 0.0 1.6e-134 448.4 0.0 1.3 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.9 GAP90595.1 - 1.4e-91 306.3 0.0 1.7e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 GAP90595.1 - 8.8e-10 38.7 0.0 2.1e-09 37.5 0.0 1.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 GAP90595.1 - 2.4e-07 30.3 0.0 2e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 GAP90595.1 - 3e-05 23.4 0.6 4.8e-05 22.7 0.3 1.4 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 GAP90595.1 - 3.4e-05 23.8 0.1 0.0011 18.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 GAP90595.1 - 0.00099 18.6 0.0 0.0019 17.7 0.0 1.4 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 GAP90595.1 - 0.0016 18.0 0.1 0.0033 17.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 GAP90595.1 - 0.002 17.2 0.3 0.0035 16.4 0.3 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 GAP90595.1 - 0.051 13.5 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.6 GAP90595.1 - 0.078 12.8 1.8 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAP90595.1 - 0.23 11.9 0.6 0.58 10.5 0.6 1.6 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 GAP90595.1 - 0.24 10.5 0.3 0.37 9.9 0.3 1.2 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 GAP90595.1 - 0.34 10.8 3.2 0.2 11.5 1.1 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 GAP90597.1 - 3.9e-14 53.2 0.0 1.2e-13 51.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP90597.1 - 5.6e-06 26.8 0.2 0.0013 19.1 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAP90597.1 - 0.0012 19.1 0.1 0.022 15.0 0.0 2.5 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 GAP90597.1 - 0.0024 17.6 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 GAP90597.1 - 0.032 14.4 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 GAP90597.1 - 0.032 14.2 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 GAP90597.1 - 0.078 12.9 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Na_Ca_ex PF01699.24 GAP90598.1 - 1.8e-29 102.7 36.0 5.5e-15 55.6 16.3 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Otopetrin PF03189.13 GAP90598.1 - 0.0088 14.9 0.7 0.013 14.3 0.7 1.2 1 0 0 1 1 1 1 Otopetrin Pkinase PF00069.25 GAP90599.1 - 2.6e-05 23.7 0.0 6.5e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP90599.1 - 0.044 13.1 0.0 0.08 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Abhydrolase_2 PF02230.16 GAP90600.1 - 1.3e-23 84.0 0.0 3e-23 82.8 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase MFS_1 PF07690.16 GAP90600.1 - 2.2e-20 72.9 53.1 9e-12 44.6 15.5 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily Peptidase_S9 PF00326.21 GAP90600.1 - 6.6e-08 32.3 0.0 7.1e-06 25.6 0.0 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 GAP90600.1 - 0.0018 17.6 0.2 1.4 8.2 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DEAD PF00270.29 GAP90605.1 - 5.9e-43 146.7 0.0 8.3e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP90605.1 - 1.2e-27 96.4 0.4 1.2e-26 93.3 0.3 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP90605.1 - 0.0018 18.3 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 GAP90605.1 - 0.03 13.7 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DnaJ PF00226.31 GAP90606.1 - 5.1e-08 32.9 0.6 9.7e-08 32.0 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_2 PF02230.16 GAP90607.1 - 4.6e-18 65.8 0.0 1.7e-17 63.9 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF3089 PF11288.8 GAP90607.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3089) GatB_N PF02934.15 GAP90609.1 - 1.4e-98 329.6 0.0 1.9e-98 329.2 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 GAP90609.1 - 0.0002 21.3 0.0 0.00047 20.1 0.0 1.6 1 0 0 1 1 1 1 GatB domain Macoilin PF09726.9 GAP90610.1 - 0.054 12.1 1.5 0.084 11.4 1.5 1.2 1 0 0 1 1 1 0 Macoilin family zf-C2H2_6 PF13912.6 GAP90611.1 - 0.029 14.4 5.3 0.2 11.7 1.7 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger DNA_pol_A_exo1 PF01612.20 GAP90611.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 3'-5' exonuclease Androgen_recep PF02166.16 GAP90611.1 - 0.48 9.2 8.3 0.78 8.5 8.3 1.2 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 GAP90611.1 - 2.2 8.2 9.0 0.84 9.6 5.0 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AA_permease_2 PF13520.6 GAP90612.1 - 2.6e-46 158.3 45.5 3.2e-46 158.0 45.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP90612.1 - 1.9e-11 43.3 45.5 7.8e-11 41.2 45.5 1.8 1 1 0 1 1 1 1 Amino acid permease DUF2633 PF11119.8 GAP90612.1 - 0.17 11.8 2.7 16 5.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) DUF3328 PF11807.8 GAP90614.1 - 3.8e-17 62.8 3.9 1.2e-16 61.2 3.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_1 PF00583.25 GAP90615.1 - 1.8e-08 34.6 0.0 5.2e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP90615.1 - 2.1e-08 34.2 0.0 1.8e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP90615.1 - 8.7e-06 26.1 0.0 1.6e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP90615.1 - 3.4e-05 23.9 0.0 0.016 15.3 0.0 2.4 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain PanZ PF12568.8 GAP90615.1 - 0.03 14.0 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 GAP90615.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein zf-C2H2 PF00096.26 GAP90619.1 - 7.5e-06 26.1 11.9 0.0028 18.0 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP90619.1 - 0.00026 21.3 3.8 0.00026 21.3 3.8 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP90619.1 - 0.00043 20.9 11.3 0.069 14.0 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 GAP90619.1 - 1.3 8.9 5.6 2.3 8.0 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PH_10 PF15411.6 GAP90620.1 - 7.2e-11 42.4 0.1 2.9e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain MFS_1 PF07690.16 GAP90621.1 - 5.1e-45 153.9 58.8 2.1e-44 151.9 58.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP90621.1 - 1.7e-11 43.7 10.2 1.7e-11 43.7 10.2 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 GAP90621.1 - 10 4.3 18.1 0.3 9.3 3.9 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Phosphodiest PF01663.22 GAP90622.1 - 4.5e-06 26.5 0.2 5.7e-05 22.9 0.0 2.3 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAP90622.1 - 0.00059 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Sulfatase GST_C_3 PF14497.6 GAP90623.1 - 1.5e-25 89.3 0.0 2.2e-24 85.5 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 GAP90623.1 - 0.00024 21.3 0.0 0.00076 19.7 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP90623.1 - 0.081 13.0 0.2 0.22 11.6 0.2 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Antimicrobial_8 PF08103.11 GAP90623.1 - 0.15 12.3 0.2 0.42 10.9 0.2 1.7 1 0 0 1 1 1 0 Uperin family VirArc_Nuclease PF12187.8 GAP90625.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral/Archaeal nuclease Glyco_hydro_18 PF00704.28 GAP90626.1 - 8.9e-73 245.7 1.1 1.4e-72 245.1 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 GAP90626.1 - 9.8e-12 45.1 16.5 9.8e-12 45.1 16.5 4.4 5 0 0 5 5 5 2 Chitin recognition protein BetaGal_dom4_5 PF13364.6 GAP90626.1 - 0.07 13.7 0.8 0.46 11.1 0.1 2.5 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain LysM PF01476.20 GAP90627.1 - 1.3e-26 92.4 3.9 8.1e-09 35.4 0.1 5.9 6 0 0 6 6 6 5 LysM domain DUF5453 PF17534.2 GAP90628.1 - 6.6 6.7 6.7 23 4.9 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5453) MFS_1 PF07690.16 GAP90629.1 - 6.8e-40 137.1 31.4 5.8e-29 101.1 6.4 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 GAP90629.1 - 0.00031 19.2 1.0 0.0016 16.9 0.6 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 GAP90629.1 - 0.0028 16.0 3.5 0.022 13.0 0.2 2.5 2 1 0 2 2 2 2 BT1 family MFS_1_like PF12832.7 GAP90629.1 - 0.038 12.8 10.2 0.0098 14.8 3.1 3.0 2 2 1 3 3 3 0 MFS_1 like family GFA PF04828.14 GAP90630.1 - 1.3e-16 60.7 1.0 1.9e-16 60.2 1.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_clus PF00172.18 GAP90631.1 - 6.3e-09 35.8 9.0 1e-08 35.1 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAP90631.1 - 0.029 13.2 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Pkinase PF00069.25 GAP90632.1 - 0.0024 17.3 0.0 6.6 6.0 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Fungal_trans PF04082.18 GAP90633.1 - 4.1e-13 49.0 11.7 1.1e-12 47.6 9.2 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 GAP90633.1 - 0.019 13.8 3.5 1.4 7.7 0.1 2.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain Pox_Ag35 PF03286.14 GAP90633.1 - 1 9.1 12.0 1.2 8.9 4.4 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein WRNPLPNID PF15017.6 GAP90633.1 - 2.9 8.9 11.2 14 6.7 5.1 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box RXT2_N PF08595.11 GAP90633.1 - 2.9 7.9 9.7 11 6.0 0.8 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal TLP-20 PF06088.11 GAP90633.1 - 6.4 6.6 8.0 14 5.5 0.8 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.6 GAP90633.1 - 6.9 6.3 12.0 2.9 7.6 1.9 2.7 3 0 0 3 3 3 0 FAM176 family zf-C2H2_3 PF13878.6 GAP90634.1 - 1.4e-10 40.8 1.4 2.7e-10 39.9 1.4 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Vma12 PF11712.8 GAP90635.1 - 4.5e-42 143.4 0.0 6.8e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Inhibitor_I53 PF11714.8 GAP90635.1 - 0.18 12.1 1.9 0.2 11.9 0.3 1.8 2 0 0 2 2 2 0 Thrombin inhibitor Madanin polyprenyl_synt PF00348.17 GAP90636.1 - 1.2e-73 247.4 0.0 1.9e-73 246.7 0.0 1.3 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 GAP90636.1 - 0.0036 16.9 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Hydrophobin PF01185.18 GAP90637.1 - 0.043 14.4 4.0 0.18 12.4 4.0 1.8 1 1 0 1 1 1 0 Fungal hydrophobin DUF3176 PF11374.8 GAP90640.1 - 1.3e-15 57.5 1.3 4.4e-15 55.8 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) F-box-like PF12937.7 GAP90642.1 - 0.0049 16.7 2.3 0.08 12.8 0.3 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 GAP90642.1 - 0.011 15.6 0.7 0.065 13.1 0.6 2.4 2 0 0 2 2 2 0 F-box domain zf-RanBP PF00641.18 GAP90642.1 - 0.056 12.8 1.1 0.16 11.3 1.1 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others F-box_4 PF15966.5 GAP90642.1 - 0.14 12.1 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 F-box zf-CCHC_2 PF13696.6 GAP90642.1 - 0.61 10.0 9.5 0.15 11.9 0.4 2.9 3 0 0 3 3 3 0 Zinc knuckle TPR_7 PF13176.6 GAP90643.1 - 5e-08 32.4 2.2 0.13 12.3 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAP90643.1 - 4.3e-07 29.5 11.0 0.0056 16.5 0.1 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAP90643.1 - 1.1e-06 28.3 18.4 0.0012 18.8 0.1 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAP90643.1 - 6.1e-05 22.8 9.4 0.0039 17.0 0.3 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAP90643.1 - 0.0053 17.0 15.3 0.064 13.6 0.1 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAP90643.1 - 0.022 14.9 5.1 24 5.5 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAP90643.1 - 0.032 14.8 16.5 0.16 12.6 0.1 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAP90643.1 - 0.053 14.0 9.1 0.056 14.0 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAP90643.1 - 0.069 14.0 18.2 20 6.4 0.0 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAP90643.1 - 0.094 12.4 12.1 13 5.6 0.4 6.6 8 0 0 8 8 8 0 TPR repeat TPR_17 PF13431.6 GAP90643.1 - 0.13 12.7 1.0 1.8e+02 2.9 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAP90643.1 - 0.65 10.7 26.7 2.4 8.9 0.1 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat DJ-1_PfpI PF01965.24 GAP90644.1 - 2.4e-16 60.0 0.0 5.4e-16 58.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 GAP90644.1 - 2.8e-10 40.2 0.0 2.1e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 GAP90644.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Amidohydro_1 PF01979.20 GAP90645.1 - 2.7e-25 89.4 0.0 4e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 GAP90645.1 - 5.3e-13 49.2 0.0 3.1e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family DUF2015 PF09435.10 GAP90646.1 - 0.17 11.8 0.1 0.51 10.2 0.1 1.8 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2015) Fungal_trans PF04082.18 GAP90648.1 - 3.1e-06 26.4 0.1 5.1e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 GAP90649.1 - 9.9e-29 100.3 0.2 3.5e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP90649.1 - 3.5e-09 36.6 11.4 5.9e-09 35.9 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 GAP90649.1 - 0.087 12.7 4.7 0.25 11.4 4.7 1.8 1 0 0 1 1 1 0 AT hook motif Glyco_hydro_92 PF07971.12 GAP90652.1 - 7.5e-152 506.5 0.1 9.3e-152 506.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAP90652.1 - 1.2e-58 198.8 0.3 2e-58 198.1 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain ADH_N_2 PF16884.5 GAP90653.1 - 1.1e-30 105.6 0.0 2.3e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 GAP90653.1 - 1.3e-20 73.7 0.0 3.7e-20 72.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP90653.1 - 2.7e-09 38.2 0.0 7.2e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Myb_DNA-binding PF00249.31 GAP90654.1 - 4.7e-16 58.7 6.8 2.4e-07 30.8 0.0 4.0 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP90654.1 - 3.5e-13 49.6 1.1 1e-09 38.5 0.1 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 GAP90654.1 - 0.0031 17.7 0.6 1.7 8.9 0.1 2.7 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 GAP90654.1 - 0.0047 17.3 5.9 0.012 16.0 1.2 2.9 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 GAP90654.1 - 0.2 11.8 1.4 1 9.5 1.4 2.3 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HET PF06985.11 GAP90655.1 - 1.1e-25 90.7 0.0 2.4e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Metallophos PF00149.28 GAP90659.1 - 5.8e-14 53.1 0.3 1.1e-13 52.2 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAP90659.1 - 7.7e-11 42.5 1.0 1.3e-09 38.5 1.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 GAP90659.1 - 0.056 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain Abhydrolase_1 PF00561.20 GAP90660.1 - 3e-18 66.4 0.0 4.8e-18 65.7 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP90660.1 - 4.7e-16 60.1 8.2 5.6e-16 59.8 8.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP90660.1 - 7.1e-10 38.6 0.0 2.6e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 GAP90660.1 - 0.0029 17.2 0.1 0.0055 16.3 0.1 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 GAP90660.1 - 0.0037 16.9 0.0 2.3 7.7 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Thioesterase PF00975.20 GAP90660.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain p450 PF00067.22 GAP90661.1 - 1.1e-48 166.1 0.0 2.4e-48 165.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.12 GAP90661.1 - 1.9e-23 83.0 0.0 2.8e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 GAP90661.1 - 3.9e-09 36.3 0.0 2e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAP90661.1 - 0.0015 18.9 0.0 0.0048 17.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 GAP90661.1 - 0.0022 16.7 0.0 0.0083 14.8 0.0 1.9 1 1 1 2 2 2 1 AMP-binding enzyme Semialdhyde_dh PF01118.24 GAP90661.1 - 0.046 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 GAP90661.1 - 0.14 12.1 0.1 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 KR domain zf-MYND PF01753.18 GAP90662.1 - 1e-08 35.1 6.5 1e-08 35.1 6.5 1.9 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 GAP90662.1 - 0.033 14.5 5.4 0.073 13.4 5.4 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 GAP90662.1 - 0.85 9.5 12.7 0.23 11.4 9.5 1.8 2 0 0 2 2 2 0 HIT zinc finger eIF3_N PF09440.10 GAP90663.1 - 1.5e-46 158.1 0.1 6.5e-46 156.1 0.4 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 GAP90663.1 - 6.4e-12 45.9 0.0 1.8e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain Img2 PF05046.14 GAP90664.1 - 5.4e-15 55.4 0.1 7.4e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) PALP PF00291.25 GAP90665.1 - 1.8e-56 191.7 5.6 2.2e-56 191.4 5.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Phage_Mu_Gp45 PF06890.12 GAP90665.1 - 0.014 15.1 1.0 0.09 12.5 0.2 2.5 3 0 0 3 3 3 0 Bacteriophage Mu Gp45 protein Mgm101p PF06420.12 GAP90665.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Collagen PF01391.18 GAP90666.1 - 0.00086 19.0 3.9 0.00086 19.0 3.9 3.1 3 1 0 3 3 3 1 Collagen triple helix repeat (20 copies) p450 PF00067.22 GAP90667.1 - 1.1e-31 110.1 0.0 1.4e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 GAP90668.1 - 1.1e-94 317.8 22.7 1.3e-94 317.6 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP90668.1 - 2.7e-26 92.3 30.4 2.7e-26 92.3 30.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 GAP90668.1 - 1.8 9.2 6.7 2.6 8.7 5.0 2.2 2 0 0 2 2 2 0 Phage holin family 2 TauD PF02668.16 GAP90669.1 - 2.1e-20 73.7 0.0 1.4e-18 67.7 0.0 2.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HAD_2 PF13419.6 GAP90669.1 - 3.2e-11 43.6 0.0 1.7e-10 41.3 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP90669.1 - 1.5e-09 37.7 0.0 4.1e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 GAP90669.1 - 0.00017 22.1 0.0 0.00028 21.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP90669.1 - 0.00072 19.9 0.0 0.025 14.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CsiD PF08943.10 GAP90669.1 - 0.0042 16.2 0.0 0.0073 15.5 0.0 1.3 1 0 0 1 1 1 1 CsiD p450 PF00067.22 GAP90671.1 - 1.6e-36 126.1 0.0 2.1e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 GAP90672.1 - 6.1e-91 305.1 0.0 4.1e-90 302.4 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP90672.1 - 6.3e-13 49.5 0.2 1.4e-12 48.4 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 GAP90672.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Clathrin PF00637.20 GAP90673.1 - 2.3e-22 79.4 1.4 3.8e-20 72.2 0.2 2.7 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.9 GAP90673.1 - 0.00037 20.8 0.1 0.0042 17.3 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 YL1 PF05764.13 GAP90673.1 - 0.00069 19.8 4.1 0.0014 18.8 4.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein zf-RING_5 PF14634.6 GAP90673.1 - 0.12 12.3 1.7 0.28 11.2 1.7 1.6 1 1 0 1 1 1 0 zinc-RING finger domain PSCyt2 PF07583.11 GAP90673.1 - 0.13 12.2 2.0 0.31 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) BUD22 PF09073.10 GAP90673.1 - 0.13 11.6 8.4 0.19 11.0 8.4 1.2 1 0 0 1 1 1 0 BUD22 TPR_2 PF07719.17 GAP90673.1 - 0.14 12.3 0.2 0.82 9.9 0.2 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat CDC45 PF02724.14 GAP90673.1 - 0.19 10.0 2.3 0.28 9.4 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TPR_7 PF13176.6 GAP90673.1 - 0.2 11.8 5.6 0.44 10.7 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 GAP90673.1 - 0.44 10.3 3.6 1 9.2 3.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger SDA1 PF05285.12 GAP90673.1 - 3.9 6.8 13.3 6.8 6.0 13.3 1.3 1 0 0 1 1 1 0 SDA1 ANAPC1 PF12859.7 GAP90674.1 - 1.2e-41 142.3 0.1 4.8e-41 140.4 0.1 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 GAP90674.1 - 3.5e-05 24.0 1.8 2.5 8.7 0.0 5.0 4 0 0 4 4 4 2 Proteasome/cyclosome repeat LBP_BPI_CETP_C PF02886.17 GAP90674.1 - 0.043 13.3 1.0 0.66 9.4 0.1 2.2 2 0 0 2 2 2 0 LBP / BPI / CETP family, C-terminal domain SprT-like PF10263.9 GAP90675.1 - 2.1e-05 24.4 0.1 3.4e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 SprT-like family DUF3267 PF11667.8 GAP90675.1 - 0.85 9.9 3.6 9.9 6.5 0.9 2.4 2 0 0 2 2 2 0 Putative zincin peptidase MFS_1 PF07690.16 GAP90676.1 - 2e-33 115.8 28.6 2e-33 115.8 28.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAP90676.1 - 4.5e-05 22.5 1.3 9.7e-05 21.4 1.4 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_4 PF06779.14 GAP90676.1 - 0.56 9.4 19.2 0.022 14.0 1.3 2.5 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Bromodomain PF00439.25 GAP90677.1 - 5.2e-19 68.1 1.7 7.1e-19 67.7 0.2 2.1 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 GAP90677.1 - 8.1e-10 38.6 0.1 2.3e-09 37.2 0.1 1.8 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 GAP90677.1 - 0.0009 19.3 0.0 0.0034 17.5 0.0 1.9 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 GAP90677.1 - 0.022 14.9 0.1 0.054 13.6 0.1 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP_like PF17027.5 GAP90677.1 - 0.048 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Histone-fold protein PSII_Pbs27 PF13326.6 GAP90677.1 - 0.053 13.8 0.2 0.17 12.2 0.2 1.9 1 0 0 1 1 1 0 Photosystem II Pbs27 PBP1_TM PF14812.6 GAP90677.1 - 0.23 11.9 11.2 0.91 9.9 3.8 3.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VanZ PF04892.12 GAP90678.1 - 6.4e-09 36.5 2.6 8.7e-09 36.1 2.6 1.2 1 0 0 1 1 1 1 VanZ like family RseC_MucC PF04246.12 GAP90678.1 - 0.063 13.2 0.5 4.3 7.3 0.4 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2279 PF10043.9 GAP90678.1 - 0.072 13.9 0.0 0.12 13.2 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) TetR_C_23 PF17931.1 GAP90678.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Na_Ca_ex PF01699.24 GAP90678.1 - 0.54 10.2 4.3 0.48 10.4 2.6 1.7 1 1 0 1 1 1 0 Sodium/calcium exchanger protein Pyridoxal_deC PF00282.19 GAP90679.1 - 1.5e-53 181.9 0.0 1.3e-46 159.1 0.1 2.6 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 GAP90679.1 - 0.0011 18.4 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 GAP90679.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Abhydrolase_3 PF07859.13 GAP90680.1 - 9.3e-52 175.9 0.6 3.1e-51 174.2 0.6 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAP90680.1 - 4.1e-06 25.9 0.1 9e-06 24.8 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 GAP90680.1 - 0.031 13.7 0.2 2.9 7.3 0.1 2.7 3 0 0 3 3 3 0 Prolyl oligopeptidase family AXE1 PF05448.12 GAP90680.1 - 0.27 9.8 0.1 0.45 9.1 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Zn_clus PF00172.18 GAP90681.1 - 4.2e-05 23.6 8.4 4.2e-05 23.6 8.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Terpene_synth_C PF03936.16 GAP90682.1 - 1.1e-05 24.9 0.6 1.5e-05 24.5 0.6 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.22 GAP90683.1 - 2.7e-38 131.9 0.0 3.6e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_21 PF05050.12 GAP90683.1 - 8e-17 61.8 0.0 2.5e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase FkbM domain Met_10 PF02475.16 GAP90683.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein V_cholerae_RfbT PF05575.11 GAP90683.1 - 0.018 14.3 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Vibrio cholerae RfbT protein UDPGT PF00201.18 GAP90684.1 - 0.0014 17.6 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_4 PF13692.6 GAP90684.1 - 0.091 13.2 0.0 0.52 10.7 0.0 2.2 3 0 0 3 3 3 0 Glycosyl transferases group 1 p450 PF00067.22 GAP90685.1 - 1.1e-45 156.3 0.0 1.7e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SnoaL_2 PF12680.7 GAP90686.1 - 0.15 12.7 0.0 0.18 12.5 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain p450 PF00067.22 GAP90687.1 - 4.1e-61 207.2 0.0 5e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAP90688.1 - 1.5e-57 195.4 0.0 2.2e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ASFV_J13L PF05568.11 GAP90689.1 - 0.0047 16.7 1.9 0.0098 15.7 1.9 1.6 1 0 0 1 1 1 1 African swine fever virus J13L protein AAA_33 PF13671.6 GAP90690.1 - 1.8e-13 50.9 0.4 3e-13 50.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 GAP90690.1 - 7e-07 29.9 0.0 1.7e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAP90690.1 - 1.8e-05 24.1 0.0 2.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 GAP90690.1 - 0.00021 21.7 0.0 0.00033 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 GAP90690.1 - 0.0005 19.9 0.0 0.00092 19.1 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 GAP90690.1 - 0.031 13.7 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sugar_tr PF00083.24 GAP90691.1 - 2.2e-67 227.9 19.2 2.6e-67 227.7 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP90691.1 - 4.4e-21 75.2 26.8 4.4e-21 75.2 26.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 GAP90691.1 - 6.8 4.9 16.9 0.39 9.0 5.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Glyco_hydro_43 PF04616.14 GAP90692.1 - 7.6e-11 41.9 1.6 1.5e-10 40.9 1.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 adh_short PF00106.25 GAP90693.1 - 8.8e-42 142.8 0.9 1.1e-41 142.5 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP90693.1 - 9.7e-30 103.8 0.7 1.2e-29 103.5 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAP90693.1 - 1.5e-05 24.6 0.7 0.00019 21.0 0.7 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 GAP90693.1 - 3e-05 23.5 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 GAP90693.1 - 9.6e-05 22.0 0.0 0.0055 16.3 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family Abhydrolase_6 PF12697.7 GAP90694.1 - 4.9e-14 53.5 2.0 5.6e-14 53.3 2.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 GAP90694.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Acyl-CoA_dh_1 PF00441.24 GAP90695.1 - 8.3e-42 142.9 0.6 1.2e-41 142.4 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAP90695.1 - 4.1e-22 78.2 0.1 7.1e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 GAP90695.1 - 2.1e-20 73.5 0.0 4.4e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 GAP90695.1 - 3.7e-19 68.6 0.3 7e-19 67.8 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 GAP90695.1 - 7.6e-09 35.9 0.0 1.4e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 GAP90695.1 - 0.19 12.3 0.0 1.6 9.3 0.0 2.3 1 1 1 2 2 2 0 C6 domain Sporozoite_P67 PF05642.11 GAP90697.1 - 0.27 9.3 2.9 0.48 8.5 2.9 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_transf_20 PF00982.21 GAP90698.1 - 2.5e-197 656.3 0.0 2.9e-197 656.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 GAP90698.1 - 0.0014 19.0 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 GAP90698.1 - 0.06 13.0 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain Tyrosinase PF00264.20 GAP90699.1 - 2.2e-33 116.4 5.1 2.2e-33 116.4 5.1 2.1 2 1 1 3 3 3 1 Common central domain of tyrosinase PSII_BNR PF14870.6 GAP90701.1 - 3.9e-08 32.9 7.8 0.032 13.5 0.0 4.6 2 2 3 5 5 5 3 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 GAP90701.1 - 2e-07 29.9 17.5 1.5 9.1 0.1 6.8 6 1 1 7 7 7 5 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 GAP90701.1 - 4.9e-06 25.6 1.9 0.019 13.8 0.0 3.1 2 2 0 3 3 3 2 Sortilin, neurotensin receptor 3, CHB_HEX_C PF03174.13 GAP90701.1 - 0.08 12.9 0.5 27 4.8 0.0 3.9 5 1 1 6 6 6 0 Chitobiase/beta-hexosaminidase C-terminal domain FAD_binding_3 PF01494.19 GAP90703.1 - 8.4e-16 58.1 0.5 2.9e-12 46.5 0.3 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAP90703.1 - 0.0017 18.6 0.1 0.011 15.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Glyco_hydro_61 PF03443.14 GAP90704.1 - 4.7e-55 186.7 0.1 4.7e-55 186.7 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Aa_trans PF01490.18 GAP90705.1 - 6.8e-77 258.9 29.7 8.1e-77 258.6 29.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TMEM37 PF15108.6 GAP90705.1 - 0.028 14.3 0.3 0.028 14.3 0.3 3.6 3 1 0 4 4 4 0 Voltage-dependent calcium channel gamma-like subunit protein family MSA-2c PF12238.8 GAP90705.1 - 0.51 10.3 2.4 1.1 9.3 2.4 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c AA_permease PF00324.21 GAP90706.1 - 3.5e-105 352.4 45.9 4.3e-105 352.1 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP90706.1 - 2.7e-25 89.1 47.3 3.3e-25 88.8 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease W2 PF02020.18 GAP90707.1 - 1.3e-22 79.7 0.7 3e-22 78.6 0.7 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 GAP90707.1 - 1.7e-11 43.3 10.9 8e-06 25.4 2.9 3.6 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAP90707.1 - 1.4e-08 34.3 5.2 0.00075 19.2 1.8 3.2 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 GAP90707.1 - 5.1e-06 25.7 0.5 0.02 13.9 0.1 2.2 1 1 1 2 2 2 2 L-fucokinase DUF4954 PF16314.5 GAP90707.1 - 0.0035 15.6 1.3 0.015 13.4 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 GAP90707.1 - 0.0046 16.6 0.0 0.0098 15.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 GAP90707.1 - 0.015 15.6 0.0 0.054 13.9 0.0 1.9 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF1385 PF07136.11 GAP90707.1 - 0.21 10.8 0.1 0.37 10.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) HSF_DNA-bind PF00447.17 GAP90709.1 - 2.2e-31 108.3 2.4 4.8e-31 107.2 2.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 GAP90709.1 - 3.2e-24 85.2 0.1 1.1e-23 83.6 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain Ets PF00178.22 GAP90709.1 - 0.082 13.4 0.1 0.22 12.0 0.1 1.7 1 0 0 1 1 1 0 Ets-domain YabA PF06156.13 GAP90709.1 - 0.15 12.7 2.1 0.34 11.6 2.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DUF2935 PF11155.8 GAP90709.1 - 0.2 12.0 1.4 0.39 11.1 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) SlyX PF04102.12 GAP90709.1 - 0.48 11.1 5.0 10 6.8 5.1 2.5 2 0 0 2 2 2 0 SlyX RCC1 PF00415.18 GAP90711.1 - 2.9e-30 104.6 2.4 6.9e-06 26.6 0.0 6.7 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 GAP90711.1 - 2.1e-14 52.9 31.1 8.1e-11 41.4 0.1 7.7 9 1 0 9 9 9 4 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.15 GAP90712.1 - 1.4e-47 161.3 0.1 2.9e-47 160.3 0.1 1.6 1 0 0 1 1 1 1 Sec34-like family Methyltransf_11 PF08241.12 GAP90713.1 - 3.7e-18 66.0 0.1 6.3e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP90713.1 - 6.1e-17 61.8 0.0 1.5e-16 60.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP90713.1 - 2.7e-16 59.8 0.0 4.9e-16 59.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP90713.1 - 4.4e-16 59.4 0.1 7.7e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP90713.1 - 2.1e-10 41.2 0.0 4.5e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAP90713.1 - 1.1e-07 32.0 0.1 2e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAP90713.1 - 1.4e-07 31.1 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 GAP90713.1 - 1.7e-06 27.8 0.0 3.7e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 GAP90713.1 - 5.4e-06 25.9 0.0 3.8e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 GAP90713.1 - 5e-05 22.4 0.0 0.00033 19.7 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1698) MTS PF05175.14 GAP90713.1 - 0.0002 20.9 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 GAP90713.1 - 0.00033 20.4 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 GAP90713.1 - 0.0012 18.7 0.1 0.0029 17.4 0.1 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 GAP90713.1 - 0.051 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 GAP90713.1 - 0.054 13.3 0.0 3.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase AP3D1 PF06375.11 GAP90713.1 - 0.086 13.1 2.8 0.26 11.5 2.9 1.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Hydrophobin_2 PF06766.11 GAP90714.1 - 0.0022 17.9 4.1 0.0069 16.3 4.1 1.8 1 1 0 1 1 1 1 Fungal hydrophobin But2 PF09792.9 GAP90715.1 - 7.2e-43 146.4 1.4 8.7e-43 146.1 1.4 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Ferric_reduct PF01794.19 GAP90716.1 - 6.7e-18 65.0 9.2 1.5e-17 63.9 9.2 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAP90716.1 - 0.00015 21.8 0.0 0.00068 19.7 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 GAP90716.1 - 0.019 15.1 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Ank_2 PF12796.7 GAP90717.1 - 2.4e-33 114.6 0.2 7e-08 33.0 0.0 6.0 6 0 0 6 6 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP90717.1 - 8.7e-26 90.0 4.7 7.2e-07 29.6 0.0 7.4 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP90717.1 - 2.3e-22 76.6 14.6 0.016 15.7 0.1 9.8 9 0 0 9 9 8 5 Ankyrin repeat Ank_5 PF13857.6 GAP90717.1 - 1.1e-16 60.6 6.2 0.016 15.5 0.1 7.8 6 2 2 8 8 7 6 Ankyrin repeats (many copies) Ank PF00023.30 GAP90717.1 - 8.1e-10 38.7 19.0 0.52 10.9 0.1 8.3 8 0 0 8 8 8 4 Ankyrin repeat NACHT PF05729.12 GAP90717.1 - 8.7e-05 22.5 0.0 0.00082 19.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GAP90717.1 - 0.0017 18.8 0.0 0.0054 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 GAP90717.1 - 0.01 16.5 1.9 0.027 15.1 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP90717.1 - 0.011 15.0 0.0 0.035 13.4 0.0 1.8 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AAA_22 PF13401.6 GAP90717.1 - 0.012 15.8 0.0 0.047 14.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAP90717.1 - 0.032 13.7 0.0 0.08 12.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 GAP90717.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAP90717.1 - 0.06 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2791 PF10923.8 GAP90717.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) DUF676 PF05057.14 GAP90717.1 - 0.16 11.4 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Glyco_hydro_18 PF00704.28 GAP90718.1 - 1.7e-47 162.7 0.4 2.8e-47 162.0 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 GAP90718.1 - 4.5e-16 58.6 0.0 3.9e-06 26.8 0.1 3.5 3 0 0 3 3 3 3 LysM domain Chitin_bind_1 PF00187.19 GAP90718.1 - 1.3e-05 25.5 8.4 1.3e-05 25.5 8.4 4.5 4 2 0 4 4 4 1 Chitin recognition protein PhoLip_ATPase_N PF16209.5 GAP90718.1 - 0.15 11.8 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 Phospholipid-translocating ATPase N-terminal WSC PF01822.19 GAP90721.1 - 3.5e-13 49.5 8.2 3.5e-13 49.5 8.2 3.4 2 1 1 3 3 3 1 WSC domain PAN_4 PF14295.6 GAP90721.1 - 0.0055 16.6 0.3 0.0055 16.6 0.3 3.6 4 0 0 4 4 4 1 PAN domain Baculo_p74_N PF08404.10 GAP90721.1 - 7.1 5.6 9.4 0.33 10.0 1.7 2.0 2 0 0 2 2 2 0 Baculoviridae P74 N-terminal Chal_sti_synt_N PF00195.19 GAP90722.1 - 6.9e-25 87.8 0.0 1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 GAP90722.1 - 6.8e-15 55.4 0.0 1.7e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 GAP90722.1 - 2.6e-06 27.5 0.2 1e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.12 GAP90722.1 - 2.2e-05 23.9 0.0 3.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 GAP90722.1 - 3.2e-05 23.7 1.5 0.00035 20.4 1.1 2.7 1 1 1 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pyr_redox PF00070.27 GAP90723.1 - 0.0017 18.9 0.9 0.0039 17.7 0.9 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP90723.1 - 0.019 15.2 2.0 0.053 13.7 2.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP90723.1 - 0.02 14.2 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ferric_reduct PF01794.19 GAP90723.1 - 0.078 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Ferric reductase like transmembrane component FAD_binding_3 PF01494.19 GAP90723.1 - 0.084 12.1 7.9 0.45 9.7 2.8 2.9 2 1 1 3 3 3 0 FAD binding domain eIF2A PF08662.11 GAP90724.1 - 2.5e-76 255.9 0.0 7.1e-76 254.4 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 GAP90724.1 - 8e-05 23.3 0.8 3.6 8.6 0.1 4.9 4 1 1 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.12 GAP90724.1 - 0.023 14.6 0.7 26 4.9 0.1 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Dermcidin PF15291.6 GAP90724.1 - 2 9.0 9.3 0.18 12.4 1.5 2.3 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide HET PF06985.11 GAP90725.1 - 9.1e-27 94.2 0.0 1.6e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF87 PF01935.17 GAP90726.1 - 0.00053 20.2 0.0 0.0024 18.0 0.0 2.0 2 1 0 2 2 2 1 Helicase HerA, central domain Zeta_toxin PF06414.12 GAP90726.1 - 0.0042 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 GAP90726.1 - 0.051 13.8 0.5 1.3 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 GAP90726.1 - 0.079 13.3 0.0 1.2 9.5 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain NAD_binding_10 PF13460.6 GAP90727.1 - 4.7e-05 23.4 0.0 6e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAP90727.1 - 0.0012 18.0 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 GAP90727.1 - 0.088 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4547 PF15080.6 GAP90727.1 - 0.18 11.4 0.0 3.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4547) DUF4780 PF16012.5 GAP90727.1 - 0.23 10.9 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) FeoB_associated PF12669.7 GAP90728.1 - 0.05 14.0 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Gram_pos_anchor PF00746.21 GAP90728.1 - 0.092 12.7 2.4 1.5 8.8 0.1 2.8 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DUF4381 PF14316.6 GAP90728.1 - 0.11 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Granulin PF00396.18 GAP90728.1 - 0.73 10.2 6.8 1.1 9.6 1.3 2.4 1 1 1 2 2 2 0 Granulin DUF3948 PF13134.6 GAP90728.1 - 0.99 9.2 3.8 1.1 9.0 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Glyco_hydro_2_C PF02836.17 GAP90729.1 - 5.9e-107 357.3 0.1 8.3e-107 356.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 GAP90729.1 - 4.8e-59 199.9 0.0 8.7e-59 199.1 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 GAP90729.1 - 1.8e-42 145.1 0.1 6.3e-42 143.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 GAP90729.1 - 2.5e-17 63.1 0.0 8.3e-17 61.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 GAP90729.1 - 1.8e-13 51.1 0.0 4.5e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 GAP90729.1 - 8.2e-05 23.1 0.3 0.00038 21.0 0.1 2.2 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Qn_am_d_aIII PF09099.10 GAP90729.1 - 0.2 12.0 1.1 1.7 9.1 0.0 2.9 4 0 0 4 4 4 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III FAD_binding_3 PF01494.19 GAP90730.1 - 3.5e-06 26.5 0.0 5.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_6 PF12697.7 GAP90732.1 - 0.00017 22.3 5.1 0.0012 19.5 0.0 2.9 3 1 0 3 3 3 1 Alpha/beta hydrolase family DUF676 PF05057.14 GAP90732.1 - 0.0061 16.1 0.1 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 GAP90732.1 - 0.0069 16.7 0.0 0.026 14.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP90732.1 - 0.019 15.4 0.0 0.067 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 GAP90732.1 - 0.031 14.2 0.1 0.072 13.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Hydrolase_4 PF12146.8 GAP90732.1 - 0.042 13.1 0.0 0.61 9.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AAA_29 PF13555.6 GAP90732.1 - 0.069 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cutinase PF01083.22 GAP90732.1 - 0.087 12.8 0.0 0.91 9.5 0.0 2.1 2 0 0 2 2 2 0 Cutinase PGAP1 PF07819.13 GAP90732.1 - 0.093 12.4 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein DUF900 PF05990.12 GAP90732.1 - 0.21 11.0 0.4 0.72 9.3 0.0 2.0 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) Cnn_1N PF07989.11 GAP90733.1 - 1.6e-20 73.0 8.7 1.6e-20 73.0 8.7 11.5 8 3 3 12 12 12 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 GAP90733.1 - 3.1e-10 40.2 14.9 3.1e-10 40.2 14.9 9.5 11 0 0 11 11 11 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Shugoshin_N PF07558.11 GAP90733.1 - 2.9 7.8 25.5 11 6.0 1.6 6.8 5 1 1 6 6 6 0 Shugoshin N-terminal coiled-coil region zf-C2H2_4 PF13894.6 GAP90735.1 - 5.1 8.2 10.9 2.3 9.3 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger CUE PF02845.16 GAP90736.1 - 2.5e-08 33.5 0.4 2e-07 30.5 0.1 2.4 2 0 0 2 2 2 1 CUE domain FA_FANCE PF11510.8 GAP90736.1 - 0.083 12.2 0.2 0.16 11.3 0.2 1.4 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE NOA36 PF06524.12 GAP90736.1 - 9.1 5.5 7.3 15 4.8 7.3 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_S10 PF00338.22 GAP90737.1 - 5.4e-25 87.5 0.2 6.5e-25 87.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.9 GAP90737.1 - 0.05 12.2 0.0 0.05 12.2 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein zf-CCCH_4 PF18044.1 GAP90738.1 - 1.4e-07 31.1 2.5 2.6e-07 30.3 2.5 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 GAP90738.1 - 0.00061 19.7 2.7 0.0022 18.0 2.7 1.9 1 1 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 GAP90738.1 - 0.0012 18.7 2.4 0.0023 17.8 2.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cellulase PF00150.18 GAP90739.1 - 3.7e-17 62.7 5.1 2.6e-16 59.9 5.1 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.22 GAP90740.1 - 1.2e-57 195.7 0.0 1.7e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5305 PF17231.2 GAP90741.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 GAP90741.1 - 0.081 13.8 0.0 0.12 13.2 0.0 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 GAP90741.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TetR_C_29 PF17938.1 GAP90741.1 - 0.18 11.9 0.2 0.3 11.2 0.2 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NMT1_2 PF13379.6 GAP90742.1 - 0.017 14.8 0.2 0.026 14.2 0.2 1.2 1 0 0 1 1 1 0 NMT1-like family SPAN PF02510.14 GAP90742.1 - 0.043 13.0 2.6 0.092 11.9 2.6 1.5 1 0 0 1 1 1 0 Surface presentation of antigens protein TPR_2 PF07719.17 GAP90743.1 - 4.1e-27 92.1 38.3 0.013 15.6 0.0 15.9 17 0 0 17 17 15 7 Tetratricopeptide repeat TPR_1 PF00515.28 GAP90743.1 - 8.4e-27 91.9 19.7 0.009 15.8 0.0 13.8 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAP90743.1 - 5.1e-24 82.4 28.9 0.19 12.0 0.0 15.0 16 0 0 16 16 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 GAP90743.1 - 6.6e-22 77.8 22.1 0.0029 18.1 0.0 10.2 8 4 3 11 11 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 GAP90743.1 - 3.4e-21 75.6 49.1 7.6e-07 29.7 0.9 12.1 11 3 1 12 12 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 GAP90743.1 - 4.9e-18 64.1 11.7 0.31 11.5 0.0 13.5 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAP90743.1 - 3e-17 61.8 38.4 7.9e-05 23.2 0.0 14.7 12 6 4 16 16 15 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAP90743.1 - 7.2e-14 51.2 24.6 0.0017 18.0 0.0 11.5 10 2 2 12 12 12 3 TPR repeat TPR_12 PF13424.6 GAP90743.1 - 1.6e-10 41.1 41.9 0.02 15.2 0.1 12.9 7 5 5 13 13 13 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAP90743.1 - 2.5e-08 34.0 14.3 0.028 14.6 0.1 7.6 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP90743.1 - 6.2e-07 29.0 24.7 0.085 12.9 0.0 11.1 12 1 1 13 13 12 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP90743.1 - 6e-05 23.2 14.6 1 9.6 0.2 7.4 4 3 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_22 PF18833.1 GAP90743.1 - 0.00024 21.2 0.0 0.0009 19.3 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP90743.1 - 0.0029 18.1 28.3 0.013 16.1 0.0 11.8 16 0 0 16 16 11 1 Tetratricopeptide repeat PPTA PF01239.22 GAP90743.1 - 0.0052 16.5 0.4 1.4 8.7 0.0 3.7 3 0 0 3 3 3 1 Protein prenyltransferase alpha subunit repeat TPR_10 PF13374.6 GAP90743.1 - 0.018 14.9 19.6 0.059 13.3 0.1 8.4 10 0 0 10 10 7 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 GAP90743.1 - 0.028 13.5 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region RPN6_N PF18055.1 GAP90743.1 - 0.24 11.8 1.6 18 5.7 0.0 3.6 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain HemY_N PF07219.13 GAP90743.1 - 3.7 7.8 9.6 22 5.3 0.2 4.8 4 1 1 5 5 5 0 HemY protein N-terminus TPR_4 PF07721.14 GAP90743.1 - 4.7 8.1 0.0 4.7 8.1 0.0 8.5 9 0 0 9 9 7 0 Tetratricopeptide repeat Glyco_hydro_5_C PF18564.1 GAP90744.1 - 3.7e-20 72.2 0.0 1e-19 70.8 0.0 1.8 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 GAP90744.1 - 1.2e-12 47.8 0.4 5.7e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 GAP90744.1 - 0.001 18.5 0.4 0.12 11.6 0.1 2.1 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.19 GAP90744.1 - 0.05 13.2 0.2 0.09 12.4 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Pkinase PF00069.25 GAP90745.1 - 2.8e-64 217.0 0.0 4.1e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP90745.1 - 5.1e-47 160.3 0.0 7.4e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP90745.1 - 9.2e-09 35.0 0.0 1.1e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 GAP90745.1 - 0.0011 17.8 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAP90745.1 - 0.03 13.7 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP90745.1 - 0.054 13.4 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family CFEM PF05730.11 GAP90746.1 - 6.8e-13 48.5 10.8 1e-12 48.0 10.8 1.3 1 0 0 1 1 1 1 CFEM domain ACC_epsilon PF13822.6 GAP90746.1 - 0.19 12.5 0.7 0.19 12.5 0.7 1.9 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Ribonuclease_T2 PF00445.18 GAP90747.1 - 1e-42 146.5 0.1 1.4e-42 146.0 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family tRNA-synt_2 PF00152.20 GAP90748.1 - 2.6e-87 292.9 0.0 3.6e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 GAP90748.1 - 2.3e-09 37.1 0.0 5.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 GAP90748.1 - 0.042 13.3 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) HIN PF02760.15 GAP90748.1 - 0.096 12.4 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 HIN-200/IF120x domain Catalase PF00199.19 GAP90749.1 - 1.7e-157 524.5 0.0 2.4e-157 524.0 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GAP90749.1 - 6.3e-13 48.7 0.2 1.3e-12 47.7 0.2 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Alpha-amylase PF00128.24 GAP90751.1 - 2.5e-89 300.2 0.9 2.5e-65 221.3 0.9 2.1 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 GAP90751.1 - 2.7e-05 24.2 0.0 5.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 GAP90751.1 - 0.00072 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Zn_clus PF00172.18 GAP90753.1 - 3.7e-07 30.1 12.6 3.7e-07 30.1 12.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.14 GAP90755.1 - 5.3e-05 22.9 0.0 0.00024 20.8 0.0 2.1 1 0 0 1 1 1 1 PQ loop repeat DUF2339 PF10101.9 GAP90755.1 - 0.00046 18.9 23.1 0.025 13.2 18.9 2.1 1 1 1 2 2 2 2 Predicted membrane protein (DUF2339) EptA_B_N PF08019.12 GAP90755.1 - 0.0066 16.3 0.6 0.0066 16.3 0.6 2.6 3 0 0 3 3 3 1 Phosphoethanolamine transferase EptA/EptB ER_lumen_recept PF00810.18 GAP90755.1 - 0.053 14.3 0.6 0.89 10.4 0.0 2.4 1 1 1 2 2 2 0 ER lumen protein retaining receptor 7TMR-DISM_7TM PF07695.11 GAP90755.1 - 0.88 9.4 17.7 5.3 6.9 16.3 2.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling Bax1-I PF01027.20 GAP90755.1 - 1 9.1 14.0 7.5 6.3 13.1 2.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 TBCC PF07986.12 GAP90757.1 - 3.7e-30 104.1 0.1 5.4e-30 103.6 0.1 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 GAP90757.1 - 2e-08 34.7 0.0 3.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain T4SS PF07996.11 GAP90757.1 - 0.072 13.5 0.1 0.21 12.0 0.1 1.7 1 1 0 1 1 1 0 Type IV secretion system proteins iPGM_N PF06415.13 GAP90758.1 - 5.3e-80 267.9 0.0 7.3e-80 267.5 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 GAP90758.1 - 9.9e-65 218.3 0.0 1.1e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 GAP90758.1 - 0.001 18.5 0.0 0.022 14.1 0.0 2.8 2 1 0 2 2 2 1 Sulfatase CSN8_PSD8_EIF3K PF10075.9 GAP90759.1 - 1.1e-40 139.0 0.0 1.5e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PDCD2_C PF04194.13 GAP90760.1 - 1.1e-39 136.3 0.0 1.4e-38 132.7 0.0 2.6 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain SpoVR PF04293.13 GAP90761.1 - 0.13 10.9 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 SpoVR like protein Rib_recp_KP_reg PF05104.12 GAP90761.1 - 0.36 11.9 5.9 0.5 11.4 5.9 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region DUF1996 PF09362.10 GAP90764.1 - 5.6e-82 275.2 0.6 7e-82 274.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) 2-Hacid_dh_C PF02826.19 GAP90766.1 - 9.5e-37 126.1 0.0 1.4e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP90766.1 - 4.1e-11 42.7 0.1 5.8e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAP90766.1 - 1.3e-07 31.9 0.0 2.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 GAP90766.1 - 0.0022 17.3 0.1 0.0036 16.6 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 GAP90766.1 - 0.0024 18.4 0.0 0.005 17.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 GAP90766.1 - 0.0033 17.3 0.2 0.0088 15.9 0.2 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAP90766.1 - 0.038 14.2 0.2 0.16 12.2 0.2 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_C PF03720.15 GAP90766.1 - 0.091 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain HET PF06985.11 GAP90768.1 - 1.5e-22 80.5 0.1 2.8e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DciA PF05258.12 GAP90769.1 - 0.0036 17.7 0.2 0.0097 16.3 0.1 1.8 2 0 0 2 2 2 1 Dna[CI] antecedent, DciA 4HBT PF03061.22 GAP90770.1 - 9.8e-09 35.5 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily F-box-like PF12937.7 GAP90770.1 - 1.1e-06 28.4 1.4 2.8e-06 27.1 1.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP90770.1 - 0.0018 18.1 1.0 0.01 15.7 0.7 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 GAP90770.1 - 0.011 15.7 1.2 0.04 13.8 0.2 2.3 3 0 0 3 3 3 0 F-box DUF1764 PF08576.10 GAP90772.1 - 0.48 11.3 8.7 1.6 9.7 5.8 3.0 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) Macoilin PF09726.9 GAP90772.1 - 1.1 7.8 5.6 1.5 7.3 5.6 1.1 1 0 0 1 1 1 0 Macoilin family NAD_binding_1 PF00175.21 GAP90774.1 - 1.3e-07 32.3 0.0 2.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAP90774.1 - 4.2e-05 23.8 0.0 0.00019 21.8 0.0 2.0 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 GAP90774.1 - 0.087 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Spo7_2_N PF15407.6 GAP90778.1 - 0.00069 19.2 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 Sporulation protein family 7 CotJB PF12652.7 GAP90779.1 - 0.14 12.4 0.6 0.58 10.4 0.1 2.2 2 0 0 2 2 2 0 CotJB protein Ribosomal_L22 PF00237.19 GAP90781.1 - 1.8e-41 140.5 0.1 3e-41 139.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF2071 PF09844.9 GAP90781.1 - 0.046 13.4 0.1 0.07 12.7 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (COG2071) Fibrillarin PF01269.17 GAP90782.1 - 4e-83 278.0 0.0 2e-82 275.7 0.0 1.8 1 1 0 1 1 1 1 Fibrillarin RXT2_N PF08595.11 GAP90783.1 - 0.0074 16.3 1.8 0.0091 16.0 1.8 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal FAM176 PF14851.6 GAP90783.1 - 0.06 13.0 1.2 0.077 12.7 1.2 1.1 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 GAP90783.1 - 0.065 13.6 8.0 0.09 13.2 8.0 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 GAP90783.1 - 0.1 13.0 6.8 0.14 12.6 6.8 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 GAP90783.1 - 0.16 11.2 7.0 0.2 11.0 7.0 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GAP90783.1 - 3.1 5.8 5.7 3.6 5.6 5.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi zf-C2H2 PF00096.26 GAP90784.1 - 0.00011 22.4 18.7 0.21 12.1 1.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP90784.1 - 0.014 16.2 19.8 0.44 11.5 0.9 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP90784.1 - 0.87 10.0 5.4 4.5 7.7 0.6 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TAZ PF02135.16 GAP90784.1 - 0.91 10.0 4.4 1 9.9 1.9 2.1 2 0 0 2 2 2 0 TAZ zinc finger zf-met PF12874.7 GAP90784.1 - 1.3 9.5 3.7 6 7.4 0.6 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type BBS2_C PF14782.6 GAP90785.1 - 0.08 11.7 0.6 0.083 11.6 0.6 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal UPF0203 PF05254.12 GAP90786.1 - 0.08 13.2 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) PAS_9 PF13426.7 GAP90787.1 - 1.4e-12 47.8 0.0 4e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 GAP90787.1 - 0.087 13.1 0.6 2.5 8.4 0.0 3.2 3 0 0 3 3 3 0 PAS fold WD40 PF00400.32 GAP90788.1 - 1.6e-20 73.1 14.8 0.00032 21.4 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP90788.1 - 4.3e-13 49.4 5.8 4.6e-05 23.6 0.5 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAP90788.1 - 3.3e-07 30.4 0.1 0.0048 16.8 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAP90788.1 - 0.073 12.0 0.1 0.5 9.3 0.0 2.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2838 PF10998.8 GAP90789.1 - 2.9e-45 153.1 11.3 2.9e-45 153.1 11.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Spc7 PF08317.11 GAP90789.1 - 0.045 12.6 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DHR10 PF18595.1 GAP90789.1 - 0.23 11.6 6.1 0.59 10.2 6.1 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Apolipoprotein PF01442.18 GAP90789.1 - 0.31 10.9 4.9 0.3 10.9 3.8 1.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Atg14 PF10186.9 GAP90789.1 - 0.38 9.8 4.0 0.6 9.1 4.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 GAP90789.1 - 0.82 7.1 3.9 1.2 6.6 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SMC_N PF02463.19 GAP90790.1 - 1.4e-41 142.4 0.0 3.8e-41 140.9 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAP90790.1 - 3.6e-26 91.8 0.0 2.3e-25 89.2 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain DUF3584 PF12128.8 GAP90790.1 - 5.8e-05 20.8 13.9 5.8e-05 20.8 13.9 5.6 4 1 0 5 5 5 2 Protein of unknown function (DUF3584) AAA_21 PF13304.6 GAP90790.1 - 0.00068 19.5 0.4 0.00068 19.5 0.4 4.9 3 3 2 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system FliJ PF02050.16 GAP90790.1 - 0.0084 16.3 7.8 0.0084 16.3 7.8 8.5 4 3 5 9 9 9 2 Flagellar FliJ protein SbcCD_C PF13558.6 GAP90790.1 - 0.0091 16.2 0.0 0.055 13.7 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Spc7 PF08317.11 GAP90790.1 - 0.033 13.1 123.8 0.007 15.3 15.0 7.0 3 2 4 7 7 7 0 Spc7 kinetochore protein DUF4795 PF16043.5 GAP90790.1 - 0.06 12.9 0.0 0.06 12.9 0.0 7.1 4 3 1 6 6 5 0 Domain of unknown function (DUF4795) FPP PF05911.11 GAP90790.1 - 0.092 10.9 93.9 0.016 13.5 38.7 4.1 3 1 0 4 4 4 0 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 GAP90790.1 - 2.5 8.3 106.6 0.14 12.4 15.8 6.2 4 1 1 5 5 5 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 GAP90790.1 - 4.1 7.5 60.0 0.39 10.7 3.9 7.3 4 1 2 6 6 6 0 Protein of unknown function (DUF1664) TFIIE_alpha PF02002.17 GAP90791.1 - 1.1e-15 57.4 0.0 2.1e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit HscB_4_cys PF18256.1 GAP90791.1 - 0.087 12.7 0.3 0.087 12.7 0.3 1.8 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif zf-Dof PF02701.15 GAP90791.1 - 0.12 12.6 0.3 0.25 11.5 0.3 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger BUD22 PF09073.10 GAP90791.1 - 0.33 10.2 17.3 0.46 9.8 17.3 1.1 1 0 0 1 1 1 0 BUD22 Mif2_N PF15624.6 GAP90791.1 - 9.5 6.9 9.5 4.1 8.1 6.4 2.0 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DNA_pol_B_thumb PF14791.6 GAP90792.1 - 6.4e-21 74.3 0.2 1.7e-20 72.9 0.2 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 GAP90792.1 - 3.7e-20 71.5 0.3 8.6e-20 70.3 0.3 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 GAP90792.1 - 5.7e-20 71.6 0.0 1.1e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 GAP90792.1 - 3.5e-10 40.1 0.0 1.1e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 GAP90792.1 - 0.0017 18.9 0.0 0.12 13.0 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 GAP90792.1 - 0.012 16.0 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain NTP_transf_2 PF01909.23 GAP90792.1 - 0.032 14.5 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain Hydrolase_4 PF12146.8 GAP90793.1 - 1.8e-45 155.1 0.0 2.2e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP90793.1 - 4.3e-14 52.8 0.2 9.1e-14 51.7 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP90793.1 - 4.3e-10 40.6 18.6 1.3e-09 39.0 5.5 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAP90793.1 - 3.9e-05 23.2 0.1 0.036 13.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 GAP90793.1 - 0.039 14.1 0.1 0.095 12.8 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain BCA_ABC_TP_C PF12399.8 GAP90793.1 - 0.86 9.6 3.5 0.86 9.6 1.6 2.1 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter Clathrin_lg_ch PF01086.17 GAP90795.1 - 1.1e-72 244.8 2.1 1.3e-72 244.6 2.1 1.0 1 0 0 1 1 1 1 Clathrin light chain SNARE PF05739.19 GAP90797.1 - 3.2e-14 52.6 0.8 3.2e-14 52.6 0.8 1.9 2 0 0 2 2 2 1 SNARE domain MCPsignal PF00015.21 GAP90797.1 - 0.00051 19.9 3.7 0.32 10.8 0.2 2.7 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.25 GAP90797.1 - 0.0015 18.2 7.3 0.029 14.1 0.2 2.2 2 0 0 2 2 2 2 Syntaxin Syntaxin_2 PF14523.6 GAP90797.1 - 0.0031 17.9 3.2 0.059 13.7 0.6 2.4 2 0 0 2 2 2 1 Syntaxin-like protein YhhN PF07947.14 GAP90797.1 - 0.042 13.5 0.1 0.063 12.9 0.1 1.1 1 0 0 1 1 1 0 YhhN family GCP_C_terminal PF04130.13 GAP90797.1 - 0.16 11.4 0.6 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal DUF2207 PF09972.9 GAP90797.1 - 0.21 10.3 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BCDHK_Adom3 PF10436.9 GAP90797.1 - 0.32 10.8 2.0 2.5 7.9 0.2 2.5 3 0 0 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase SlyX PF04102.12 GAP90797.1 - 7.7 7.2 9.9 1.1 9.9 0.4 3.5 2 2 2 4 4 4 0 SlyX EF-hand_1 PF00036.32 GAP90798.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 GAP90798.1 - 2.2e-36 124.1 5.3 2.6e-19 69.4 1.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 GAP90798.1 - 3.5e-35 119.6 11.0 1.5e-15 56.8 0.5 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 GAP90798.1 - 7.3e-31 103.4 8.1 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 GAP90798.1 - 6.4e-26 88.7 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 GAP90798.1 - 9.8e-17 61.0 0.3 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 GAP90798.1 - 4e-09 36.8 0.2 0.0011 19.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 GAP90798.1 - 6.6e-09 35.7 1.7 0.0016 18.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 GAP90798.1 - 7.1e-07 29.2 0.1 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 GAP90798.1 - 1e-05 25.5 1.6 4.5e-05 23.5 0.2 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 GAP90798.1 - 2.7e-05 25.0 0.2 0.00066 20.5 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 GAP90798.1 - 9.7e-05 22.4 0.4 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 GAP90798.1 - 0.00042 20.3 1.8 0.44 10.5 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 GAP90798.1 - 0.00075 19.8 1.0 0.73 10.2 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 GAP90798.1 - 0.0016 19.2 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 GAP90798.1 - 0.0018 18.4 5.4 0.3 11.3 0.4 2.9 1 1 1 2 2 2 2 Dockerin type I domain DUF5580 PF17743.1 GAP90798.1 - 0.0048 15.5 0.0 0.005 15.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 GAP90798.1 - 0.009 15.9 0.9 0.3 10.9 0.2 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 GAP90798.1 - 0.01 16.1 0.4 5.7 7.3 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 GAP90798.1 - 0.019 15.2 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 GAP90798.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) MotA_activ PF09114.10 GAP90798.1 - 0.063 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain RuvA_C PF07499.13 GAP90798.1 - 0.068 13.6 0.1 10 6.7 0.1 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 GAP90798.1 - 0.072 12.3 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain RloB PF13707.6 GAP90798.1 - 0.16 12.2 1.2 0.79 9.9 0.6 2.0 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 GAP90798.1 - 0.17 12.0 0.7 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) ABC_membrane PF00664.23 GAP90799.1 - 4.2e-48 164.4 10.7 5.4e-48 164.0 10.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 GAP90799.1 - 4.4e-34 117.9 0.0 9.1e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 GAP90799.1 - 0.0024 18.1 0.1 0.016 15.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 GAP90799.1 - 0.0041 16.6 3.5 0.15 11.5 3.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 GAP90799.1 - 0.0059 17.0 0.0 0.021 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 GAP90799.1 - 0.0098 15.6 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAP90799.1 - 0.015 15.0 0.1 0.058 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAP90799.1 - 0.021 14.6 0.1 0.061 13.1 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.29 GAP90799.1 - 0.039 13.7 0.1 0.3 10.8 0.1 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 GAP90799.1 - 0.044 14.2 0.1 0.28 11.6 0.0 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 GAP90799.1 - 0.098 12.9 1.2 1.4 9.2 1.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 GAP90799.1 - 0.14 12.1 0.1 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 GAP90799.1 - 0.14 11.8 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein CTD_bind PF04818.13 GAP90801.1 - 2.1e-18 66.9 0.1 7.6e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CREPT PF16566.5 GAP90801.1 - 0.0053 16.9 0.3 0.013 15.7 0.0 1.7 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour CTK3 PF12243.8 GAP90801.1 - 0.031 14.3 0.7 0.046 13.7 0.1 1.6 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 HOIP-UBA PF16678.5 GAP90801.1 - 0.042 13.8 0.3 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair MCD_N PF17408.2 GAP90801.1 - 0.11 12.7 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain SPESP1 PF15754.5 GAP90801.1 - 0.12 11.5 1.7 0.2 10.8 1.7 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Trypan_PARP PF05887.11 GAP90801.1 - 1.7 8.6 15.7 2.8 7.9 15.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ATG16 PF08614.11 GAP90802.1 - 3.3 7.9 7.5 0.99 9.6 4.4 1.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) MctB PF11382.8 GAP90803.1 - 0.094 12.4 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Acetyltransf_1 PF00583.25 GAP90804.1 - 3.4e-12 46.6 0.0 4.5e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP90804.1 - 4.3e-11 42.9 0.0 6.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP90804.1 - 2.2e-09 37.6 0.0 3.7e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP90804.1 - 2.8e-07 30.4 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DUF5643 PF18705.1 GAP90804.1 - 0.0021 18.0 0.0 0.0046 16.9 0.0 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5643) Acetyltransf_9 PF13527.7 GAP90804.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAP90804.1 - 0.052 13.7 0.0 0.094 12.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.6 GAP90805.1 - 1.8e-43 148.8 0.2 2.3e-43 148.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP90805.1 - 1.3e-41 142.3 0.1 1.5e-41 142.0 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP90805.1 - 2.1e-12 47.4 0.1 2.8e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 GAP90805.1 - 0.037 14.1 0.1 0.045 13.8 0.1 1.3 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N PF00107.26 GAP90805.1 - 0.098 12.6 0.1 5 7.1 0.0 2.6 2 1 1 3 3 3 0 Zinc-binding dehydrogenase 3Beta_HSD PF01073.19 GAP90805.1 - 0.11 11.5 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CbiA PF01656.23 GAP90805.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1793 PF08760.11 GAP90806.1 - 3.5e-73 245.5 4.0 3.7e-73 245.4 2.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 GAP90806.1 - 6e-68 227.9 0.0 1.3e-53 181.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 GAP90806.1 - 1e-41 143.2 0.9 1.9e-41 142.3 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) Glyco_hydr_116N PF12215.8 GAP90806.1 - 0.001 18.6 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF4964 PF16334.5 GAP90806.1 - 0.0031 17.0 0.1 0.0072 15.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) RRM_1 PF00076.22 GAP90807.1 - 1.8e-18 66.1 0.0 2.6e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAP90807.1 - 9.1e-05 22.1 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec39 PF08314.11 GAP90809.1 - 7.7e-282 937.2 0.0 9e-282 937.0 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.9 GAP90810.1 - 0.00021 21.5 0.1 0.00026 21.2 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 GAP90810.1 - 0.0076 16.6 1.4 0.021 15.2 1.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 GAP90810.1 - 0.032 14.4 0.4 0.051 13.8 0.4 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb COX17 PF05051.13 GAP90810.1 - 0.052 13.9 0.4 0.1 12.9 0.4 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 GAP90810.1 - 0.055 13.7 3.1 0.091 13.0 3.1 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) NAD_binding_6 PF08030.12 GAP90813.1 - 0.00055 20.1 0.1 0.62 10.2 0.1 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 GAP90813.1 - 0.00073 20.2 0.1 2.3 8.9 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 GAP90813.1 - 0.0067 16.8 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain SSP160 PF06933.11 GAP90813.1 - 0.015 13.6 9.4 0.02 13.2 9.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 GAP90813.1 - 0.39 10.7 8.3 0.73 9.8 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.11 GAP90813.1 - 0.45 8.5 4.5 0.7 7.9 4.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Adaptin_N PF01602.20 GAP90814.1 - 2e-143 478.8 2.7 2.3e-143 478.5 2.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 GAP90814.1 - 5.1e-21 75.1 0.0 1.3e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 GAP90814.1 - 7.6e-08 32.6 4.4 0.00021 21.4 0.0 3.6 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAP90814.1 - 2.7e-06 27.6 2.7 0.051 14.0 0.0 4.0 4 2 0 4 4 3 2 HEAT repeats DUF3730 PF12530.8 GAP90814.1 - 9.6e-05 22.1 0.1 0.008 15.8 0.1 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3730) HEAT PF02985.22 GAP90814.1 - 0.00082 19.4 1.5 4.3 7.9 0.1 4.8 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 GAP90814.1 - 0.007 16.8 0.4 39 4.9 0.0 4.8 4 0 0 4 4 4 0 HEAT-like repeat TIP120 PF08623.10 GAP90814.1 - 0.015 15.1 1.0 3.5 7.4 0.0 3.0 3 1 0 3 3 3 0 TATA-binding protein interacting (TIP20) RIX1 PF08167.12 GAP90814.1 - 0.033 13.9 0.4 0.12 12.1 0.0 2.3 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Arm PF00514.23 GAP90814.1 - 0.055 13.5 0.6 1.4e+02 2.7 0.0 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat NlpE PF04170.12 GAP90814.1 - 0.081 13.9 0.0 0.23 12.4 0.0 1.8 1 0 0 1 1 1 0 NlpE N-terminal domain CLASP_N PF12348.8 GAP90814.1 - 0.12 11.9 0.9 3 7.3 0.0 2.8 3 0 0 3 3 3 0 CLASP N terminal TonB_2 PF13103.6 GAP90814.1 - 0.18 12.1 0.0 0.47 10.7 0.0 1.7 1 0 0 1 1 1 0 TonB C terminal MAPEG PF01124.18 GAP90815.1 - 2e-19 69.8 3.8 2.4e-19 69.5 3.8 1.1 1 0 0 1 1 1 1 MAPEG family Peptidase_M14 PF00246.24 GAP90816.1 - 4e-68 230.3 0.0 6.7e-68 229.6 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.20 GAP90817.1 - 8.9e-30 103.7 0.2 1.4e-29 103.1 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 GAP90817.1 - 0.00031 21.2 0.0 0.00092 19.7 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 GAP90817.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain YfdX PF10938.8 GAP90817.1 - 0.06 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 YfdX protein OEP PF02321.18 GAP90817.1 - 0.061 13.1 0.8 0.11 12.4 0.8 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein SRP_TPR_like PF17004.5 GAP90818.1 - 1.3e-22 80.0 0.2 3e-22 78.8 0.2 1.7 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 GAP90818.1 - 2.9e-16 59.6 9.0 2.9e-16 59.6 9.0 2.3 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 GAP90818.1 - 3.9e-07 30.5 15.2 0.025 15.1 0.2 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP90818.1 - 0.0015 18.7 1.1 0.26 11.5 0.6 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAP90818.1 - 0.018 15.1 14.2 1.3 9.3 0.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAP90818.1 - 0.026 15.1 6.0 0.026 15.1 6.0 5.3 3 2 2 5 5 5 0 Tetratricopeptide repeat GGA_N-GAT PF18308.1 GAP90818.1 - 0.061 13.0 0.1 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 GGA N-GAT domain TPR_4 PF07721.14 GAP90818.1 - 7.7 7.5 17.1 4.7 8.1 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Tropomyosin_1 PF12718.7 GAP90819.1 - 8.5e-05 22.7 7.9 0.086 13.0 1.4 2.4 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 GAP90819.1 - 0.023 14.0 8.1 0.13 11.6 0.5 2.1 1 1 1 2 2 2 0 Tropomyosin Gp58 PF07902.11 GAP90819.1 - 0.071 11.4 0.3 0.098 10.9 0.3 1.1 1 0 0 1 1 1 0 gp58-like protein Jnk-SapK_ap_N PF09744.9 GAP90819.1 - 0.091 13.0 4.5 0.052 13.8 2.4 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 CorA PF01544.18 GAP90819.1 - 0.12 11.6 6.2 0.28 10.5 6.2 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.19 GAP90819.1 - 0.25 9.2 0.4 0.32 8.9 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4404 PF14357.6 GAP90819.1 - 0.4 11.3 1.7 0.55 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) PspB PF06667.12 GAP90819.1 - 0.41 10.7 3.2 8.8 6.5 0.2 2.5 2 0 0 2 2 2 0 Phage shock protein B DUF1664 PF07889.12 GAP90819.1 - 0.66 10.0 4.5 5 7.2 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 GAP90819.1 - 1.2 9.4 3.3 20 5.5 0.3 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain XhlA PF10779.9 GAP90819.1 - 1.9 8.8 5.0 0.57 10.4 1.3 2.1 2 1 0 2 2 2 0 Haemolysin XhlA SlyX PF04102.12 GAP90819.1 - 2.1 9.0 10.5 0.88 10.2 0.5 3.5 3 1 0 3 3 2 0 SlyX DUF1465 PF07323.12 GAP90819.1 - 2.4 8.0 6.0 1.2 9.0 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) MscS_porin PF12795.7 GAP90819.1 - 3.6 7.0 5.5 21 4.6 0.4 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Pox_A_type_inc PF04508.12 GAP90819.1 - 4.7 7.2 5.9 2.3 8.2 2.0 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Csm1_N PF18504.1 GAP90819.1 - 5 7.5 5.8 18 5.7 0.1 2.7 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF4140 PF13600.6 GAP90819.1 - 5.6 7.5 5.3 38 4.8 0.7 2.6 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) CLZ PF16526.5 GAP90819.1 - 6.8 7.1 8.3 11 6.5 1.3 3.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NCBP3 PF10309.9 GAP90820.1 - 3.4e-17 62.0 0.0 5.5e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Myb_DNA-binding PF00249.31 GAP90824.1 - 2.7e-23 81.9 2.6 1.4e-11 44.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP90824.1 - 3.5e-17 62.4 3.5 8.5e-13 48.4 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Glyco_transf_41 PF13844.6 GAP90825.1 - 4e-99 332.2 0.0 3.5e-50 170.8 0.0 3.2 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 GAP90825.1 - 4.6e-20 70.5 4.1 0.0014 18.4 0.0 5.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 GAP90825.1 - 1.5e-16 59.0 4.5 0.0022 18.0 0.2 6.1 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 GAP90825.1 - 6.2e-13 47.9 0.5 0.046 13.9 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 GAP90825.1 - 3.9e-12 45.6 0.8 0.027 14.1 0.0 5.7 3 2 3 6 6 6 3 TPR repeat TPR_12 PF13424.6 GAP90825.1 - 8.9e-12 45.1 5.4 0.0011 19.2 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 GAP90825.1 - 1e-10 41.1 6.8 0.045 13.7 0.5 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAP90825.1 - 2.4e-08 33.8 0.6 0.34 11.4 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAP90825.1 - 1.7e-07 31.7 2.2 2.5 8.8 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAP90825.1 - 6.4e-07 29.7 3.3 3.9 8.5 0.0 5.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAP90825.1 - 6.8e-05 22.6 1.7 1.6 8.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAP90825.1 - 7.4e-05 23.2 3.5 5.7 7.5 0.0 4.8 3 2 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP90825.1 - 0.0026 17.9 0.8 0.12 12.6 0.1 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 GAP90825.1 - 0.024 15.1 1.8 0.47 10.9 0.0 2.6 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Ribosomal_L11_N PF03946.14 GAP90826.1 - 4.6e-25 87.2 0.2 8.1e-25 86.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 GAP90826.1 - 5.5e-15 55.6 0.1 9.4e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.15 GAP90827.1 - 3.5e-81 272.4 0.0 5.1e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 GAP90827.1 - 2.9e-30 104.8 0.4 5.7e-30 103.9 0.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 GAP90827.1 - 1.7e-25 88.8 0.1 4.5e-25 87.5 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 GAP90827.1 - 6.1e-16 58.2 6.1 1.2e-15 57.3 6.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAP90827.1 - 2.2e-13 49.9 0.0 5.8e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 GAP90827.1 - 0.0083 15.5 0.7 0.025 14.0 0.1 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Yuri_gagarin PF15934.5 GAP90829.1 - 0.22 11.3 4.4 0.11 12.3 0.7 2.2 2 1 0 2 2 2 0 Yuri gagarin TMF_DNA_bd PF12329.8 GAP90829.1 - 0.35 10.9 24.0 0.17 11.9 0.4 5.0 5 1 1 6 6 6 0 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 GAP90829.1 - 0.39 10.6 12.5 4.4 7.2 0.3 5.2 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HIP1_clath_bdg PF16515.5 GAP90829.1 - 0.51 11.0 28.9 1.7 9.3 6.4 5.4 5 1 1 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FlxA PF14282.6 GAP90829.1 - 4.6 7.3 14.8 0.3 11.1 7.1 3.0 2 2 0 2 2 2 0 FlxA-like protein UPF0242 PF06785.11 GAP90829.1 - 7.7 6.6 21.4 0.35 11.0 4.9 3.7 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus API5 PF05918.11 GAP90830.1 - 0.39 9.5 1.6 0.46 9.3 1.6 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FoP_duplication PF13865.6 GAP90830.1 - 1.9 9.1 6.9 3 8.4 6.9 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 LrgB PF04172.16 GAP90831.1 - 7.9e-48 162.8 7.0 7.9e-48 162.8 7.0 2.6 3 1 0 3 3 3 1 LrgB-like family LrgA PF03788.14 GAP90831.1 - 0.0049 16.8 6.7 0.0049 16.8 6.7 3.1 2 2 0 2 2 2 1 LrgA family Lactamase_B_6 PF16661.5 GAP90832.1 - 9.8e-64 214.3 0.0 2.8e-63 212.8 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 GAP90832.1 - 6e-51 173.0 0.2 1.5e-50 171.7 0.0 1.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 GAP90832.1 - 2.3e-17 63.3 0.0 7.3e-17 61.7 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 GAP90832.1 - 1e-12 47.8 0.1 3e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Sec23_trunk PF04811.15 GAP90833.1 - 3.7e-50 170.8 0.0 7.8e-50 169.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 GAP90833.1 - 5.8e-24 83.9 0.0 1.2e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 GAP90833.1 - 2.2e-17 63.6 0.0 4.1e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 GAP90833.1 - 1.8e-15 56.7 4.8 4.2e-15 55.5 4.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 GAP90833.1 - 7.4e-05 22.6 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat DUF2263 PF10021.9 GAP90834.1 - 7.4e-09 36.1 0.0 1.1e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) SR-25 PF10500.9 GAP90834.1 - 1.4 8.5 11.3 2.1 7.9 11.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 GAP90834.1 - 7.7 6.8 15.5 12 6.1 15.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) tRNA-synt_2 PF00152.20 GAP90835.1 - 7.5e-82 274.9 0.0 9.2e-82 274.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Gti1_Pac2 PF09729.9 GAP90836.1 - 1.1e-42 146.2 10.8 2.7e-37 128.6 0.2 3.0 2 1 1 3 3 3 2 Gti1/Pac2 family HlyIII PF03006.20 GAP90837.1 - 5.6e-53 179.9 18.9 7e-53 179.6 18.9 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF2678 PF10856.8 GAP90837.1 - 1.7 8.6 5.2 0.44 10.5 1.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2678) ER_lumen_recept PF00810.18 GAP90837.1 - 2.2 9.1 7.8 0.58 11.0 4.0 1.8 2 0 0 2 2 2 0 ER lumen protein retaining receptor Linker_histone PF00538.19 GAP90838.1 - 1.3e-28 99.2 0.1 2.9e-28 98.0 0.1 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Dishevelled PF02377.15 GAP90839.1 - 2.2 8.7 15.3 0.083 13.3 7.3 2.7 3 0 0 3 3 3 0 Dishevelled specific domain zf-trcl PF13451.6 GAP90840.1 - 0.026 14.4 3.1 0.14 12.1 0.7 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain DTHCT PF08070.11 GAP90841.1 - 0.026 15.3 0.3 0.026 15.3 0.3 3.2 3 1 0 3 3 3 0 DTHCT (NUC029) region HET PF06985.11 GAP90842.1 - 6.6e-16 59.0 0.0 1.7e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3446 PF11928.8 GAP90842.1 - 0.0058 16.9 3.0 0.0058 16.9 3.0 2.8 3 0 0 3 3 3 1 Early growth response N-terminal domain CENP-B_dimeris PF09026.10 GAP90842.1 - 0.0076 16.6 11.2 0.1 13.0 4.3 2.5 2 0 0 2 2 2 2 Centromere protein B dimerisation domain GCIP PF13324.6 GAP90842.1 - 0.2 11.3 1.2 0.38 10.3 0.1 1.9 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting FAM176 PF14851.6 GAP90842.1 - 0.2 11.3 1.6 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 FAM176 family DUF3439 PF11921.8 GAP90842.1 - 0.67 9.9 13.1 0.25 11.3 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Serglycin PF04360.12 GAP90843.1 - 0.056 13.4 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 Serglycin MutS_V PF00488.21 GAP90844.1 - 1.2e-82 276.5 0.0 1.9e-82 275.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 GAP90844.1 - 2.4e-38 132.3 0.9 9.4e-38 130.4 0.6 2.2 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 GAP90844.1 - 9.6e-23 81.0 2.3 4e-22 79.0 0.0 3.0 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 GAP90844.1 - 1.7e-19 70.1 0.0 1e-18 67.6 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 GAP90844.1 - 1.2e-17 64.0 2.8 6.3e-17 61.7 1.5 2.7 2 0 0 2 2 2 1 MutS family domain IV AAA_27 PF13514.6 GAP90844.1 - 0.083 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain RST PF12174.8 GAP90844.1 - 0.15 12.0 0.2 0.5 10.3 0.2 1.9 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain tRNA_m1G_MT PF01746.21 GAP90845.1 - 2.1e-26 92.8 0.0 2.5e-18 66.5 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Fungal_trans_2 PF11951.8 GAP90846.1 - 9e-11 41.2 5.2 1e-09 37.7 5.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain FYDLN_acid PF09538.10 GAP90846.1 - 0.041 14.6 3.7 0.41 11.3 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.6 GAP90846.1 - 0.057 13.1 0.1 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 FAM176 family DUF2859 PF11072.8 GAP90846.1 - 0.087 12.6 1.9 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) DUF4834 PF16118.5 GAP90846.1 - 0.24 12.4 0.4 0.24 12.4 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DivIC PF04977.15 GAP90846.1 - 0.57 10.0 6.8 0.65 9.8 4.8 1.9 2 0 0 2 2 2 0 Septum formation initiator E_Pc_C PF06752.12 GAP90846.1 - 1.2 9.1 5.7 1.9 8.6 5.7 1.4 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus HemY_N PF07219.13 GAP90846.1 - 1.3 9.2 5.2 25 5.1 1.6 2.6 2 1 1 3 3 3 0 HemY protein N-terminus Spt20 PF12090.8 GAP90846.1 - 2.8 7.5 11.6 4 7.0 11.6 1.1 1 0 0 1 1 1 0 Spt20 family UPF0560 PF10577.9 GAP90846.1 - 5.8 5.3 7.8 0.47 8.9 1.3 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Fungal_trans_2 PF11951.8 GAP90847.1 - 1.2e-12 47.3 0.0 1.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP90847.1 - 5.5e-07 29.6 8.9 9.8e-07 28.8 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4124 PF13511.6 GAP90847.1 - 0.093 13.1 0.2 0.093 13.1 0.2 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4124) IMUP PF15761.5 GAP90847.1 - 8.7 7.1 11.2 1.5 9.5 7.4 1.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein MFS_1 PF07690.16 GAP90848.1 - 1.4e-34 119.6 59.1 5.7e-34 117.6 57.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Cytochrom_B558a PF05038.13 GAP90848.1 - 0.4 10.2 5.6 7.8 6.0 1.0 2.8 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Cellulase PF00150.18 GAP90850.1 - 5.9e-19 68.6 0.7 1.9e-18 66.9 0.7 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Myc_N PF01056.18 GAP90851.1 - 0.00054 20.0 1.1 0.00056 19.9 1.1 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Tim54 PF11711.8 GAP90851.1 - 0.012 14.4 0.8 0.014 14.2 0.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.6 GAP90851.1 - 0.033 13.8 0.8 0.034 13.8 0.8 1.1 1 0 0 1 1 1 0 FAM176 family RAB3GAP2_C PF14656.6 GAP90851.1 - 0.11 10.7 0.1 0.13 10.5 0.1 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF3824 PF12868.7 GAP90851.1 - 0.18 12.5 1.4 0.24 12.0 1.4 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Oxysterol_BP PF01237.18 GAP90852.1 - 9.6e-51 172.8 0.0 1.7e-48 165.4 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Fungal_trans PF04082.18 GAP90853.1 - 3.2e-18 65.7 0.7 5.9e-18 64.8 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP90853.1 - 4.4e-08 33.1 9.6 7.3e-08 32.4 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Imm70 PF15601.6 GAP90853.1 - 0.097 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 70 CP2 PF04516.15 GAP90855.1 - 2.9e-80 268.9 0.0 4.6e-80 268.2 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 GAP90855.1 - 0.05 12.3 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Tektin family PAF-AH_p_II PF03403.13 GAP90858.1 - 5.1e-15 54.9 0.1 1.8e-06 26.7 0.0 2.8 3 1 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 GAP90858.1 - 0.00012 21.1 0.1 0.014 14.4 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 GAP90858.1 - 0.00021 22.0 9.1 0.00021 22.0 9.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP90858.1 - 0.007 15.7 0.0 0.55 9.4 0.1 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP90858.1 - 0.026 14.2 0.1 1.1 8.9 0.0 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 GAP90858.1 - 0.15 11.1 0.2 1.9 7.4 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase Peptidase_S9 PF00326.21 GAP90858.1 - 0.15 11.5 0.3 0.3 10.5 0.3 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 GAP90858.1 - 0.18 11.5 0.3 2.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family RebB PF11747.8 GAP90860.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 Killing trait MFS_1 PF07690.16 GAP90861.1 - 1.7e-37 129.2 42.6 4.7e-37 127.7 32.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP90861.1 - 8.5e-06 24.9 8.5 8.5e-06 24.9 8.5 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Sulfate_transp PF00916.20 GAP90862.1 - 1e-108 363.5 17.9 1.3e-108 363.2 17.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAP90862.1 - 7e-06 25.7 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 GAP90862.1 - 0.0018 18.7 4.5 0.0018 18.7 4.5 3.3 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily zf-C2H2 PF00096.26 GAP90863.1 - 2.8e-08 33.8 20.4 0.002 18.5 6.6 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP90863.1 - 8.7e-07 29.1 12.3 0.0049 17.2 3.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP90863.1 - 0.00039 21.0 20.0 0.12 13.3 5.9 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 GAP90863.1 - 0.83 9.5 8.9 2.9 7.7 1.7 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 GAP90863.1 - 3.3 7.8 7.0 26 5.0 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Rhodanese PF00581.20 GAP90864.1 - 8.9e-09 35.8 0.0 1.2e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain YL1 PF05764.13 GAP90865.1 - 0.16 12.1 3.6 0.21 11.7 3.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 GAP90865.1 - 7 5.9 5.0 10 5.4 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein Arginase PF00491.21 GAP90866.1 - 1e-76 258.2 0.1 1.2e-76 257.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.23 GAP90867.1 - 1.8e-05 24.8 14.2 2.7e-05 24.2 14.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain Glyco_transf_90 PF05686.12 GAP90868.1 - 1.4e-13 50.5 0.2 3.1e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 RrnaAD PF00398.20 GAP90869.1 - 3.1e-07 29.7 0.0 6.7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ank_2 PF12796.7 GAP90871.1 - 1.4e-20 73.7 4.9 5.2e-10 39.8 2.5 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP90871.1 - 3.2e-15 56.0 5.6 1.3e-05 25.3 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP90871.1 - 1.5e-14 52.6 3.4 0.00056 20.2 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 GAP90871.1 - 3.5e-14 53.0 4.1 1.3e-06 28.8 0.4 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 GAP90871.1 - 3.5e-13 49.3 8.6 2.1e-05 24.7 0.5 4.3 4 0 0 4 4 4 3 Ankyrin repeat PNPase_C PF12111.8 GAP90871.1 - 0.89 9.0 8.4 3.2 7.3 8.4 1.9 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal SLBB PF10531.9 GAP90872.1 - 0.051 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 SLBB domain DUF1993 PF09351.10 GAP90873.1 - 5.7e-47 159.8 0.0 6.4e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DeoC PF01791.9 GAP90874.1 - 3.5e-10 39.9 1.4 6e-10 39.1 1.4 1.3 1 0 0 1 1 1 1 DeoC/LacD family aldolase Fungal_trans PF04082.18 GAP90874.1 - 0.15 11.1 0.0 0.32 10.0 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF1479 PF07350.12 GAP90875.1 - 3.2e-161 536.7 0.0 3.8e-161 536.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 GAP90875.1 - 0.0003 21.1 0.0 0.057 13.7 0.1 2.4 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 GAP90876.1 - 3e-36 125.1 34.6 3e-36 125.1 34.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 GAP90876.1 - 8.8e-05 21.1 3.4 0.00011 20.7 1.0 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector TRI12 PF06609.13 GAP90876.1 - 0.00012 20.6 4.7 0.00023 19.7 4.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.21 GAP90877.1 - 7.2e-45 153.4 0.0 8.6e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CTP_transf_3 PF02348.19 GAP90877.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Zn_clus PF00172.18 GAP90878.1 - 1.3e-08 34.8 12.8 2.4e-08 34.0 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 GAP90879.1 - 5e-75 252.3 0.0 8.3e-75 251.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 GAP90879.1 - 1.6e-73 247.7 0.0 2.9e-73 246.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 GAP90879.1 - 3.7e-68 230.3 0.3 5.4e-68 229.7 0.3 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 GAP90879.1 - 1.7e-55 187.7 0.1 6.5e-54 182.6 0.0 2.9 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 GAP90879.1 - 2.6e-48 165.2 0.0 5.6e-48 164.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAP90879.1 - 1.6e-46 158.9 0.0 2.9e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.12 GAP90879.1 - 1.4e-39 135.8 0.0 5.6e-39 133.9 0.0 2.1 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 GAP90879.1 - 1.3e-28 99.4 0.1 2.8e-28 98.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAP90879.1 - 3.5e-20 72.6 0.0 9.9e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAP90879.1 - 3.6e-16 59.2 0.0 1.2e-14 54.2 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.25 GAP90879.1 - 4.4e-16 59.0 1.7 1.8e-09 37.8 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 GAP90879.1 - 3.5e-15 56.1 0.0 1.7e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 GAP90879.1 - 5.8e-15 55.8 0.0 2.2e-14 53.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP90879.1 - 1.7e-14 53.9 0.0 4.1e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP90879.1 - 8.9e-14 51.9 0.0 3.4e-13 50.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP90879.1 - 1.6e-13 50.8 0.0 4.5e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAP90879.1 - 3.7e-13 49.9 0.0 1e-12 48.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension 3Beta_HSD PF01073.19 GAP90879.1 - 2.3e-12 46.5 0.0 5.1e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 GAP90879.1 - 4.4e-07 29.5 0.0 9.6e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 GAP90879.1 - 7.9e-07 28.9 0.0 2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 GAP90879.1 - 0.00039 19.9 0.0 0.0008 18.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 GAP90879.1 - 0.00054 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 GAP90879.1 - 0.0012 18.3 0.0 0.81 9.0 0.0 2.6 3 0 0 3 3 2 2 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 GAP90879.1 - 0.0031 18.5 0.0 0.011 16.7 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_8 PF05148.15 GAP90879.1 - 0.033 14.0 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase NAD_binding_10 PF13460.6 GAP90879.1 - 0.038 13.9 0.0 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H-binding NodS PF05401.11 GAP90879.1 - 0.048 13.3 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) p450 PF00067.22 GAP90880.1 - 2.4e-35 122.2 0.0 3.3e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAP90881.1 - 3e-47 161.3 50.7 5.8e-47 160.3 50.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP90881.1 - 4.2e-17 61.8 15.3 6.6e-17 61.2 15.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP90881.1 - 2e-13 50.0 13.5 2e-13 50.0 13.5 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.21 GAP90881.1 - 0.0038 16.1 1.8 0.0038 16.1 1.8 2.2 3 0 0 3 3 3 1 POT family HIGH_NTase1_ass PF16581.5 GAP90881.1 - 0.27 11.2 0.0 0.41 10.6 0.0 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Abhydrolase_6 PF12697.7 GAP90882.1 - 2.7e-06 28.2 0.1 7.1e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP90882.1 - 0.0024 17.2 0.0 0.0077 15.5 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAP90882.1 - 0.0038 16.7 0.2 0.0079 15.7 0.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family ADH_zinc_N PF00107.26 GAP90884.1 - 4.4e-08 33.2 0.0 9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP90884.1 - 2.7e-06 27.2 0.3 4.8e-05 23.2 0.2 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.22 GAP90885.1 - 5.9e-40 137.4 0.0 7.9e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.6 GAP90886.1 - 1.8e-16 60.3 0.0 5.9e-15 55.3 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP90886.1 - 7.5e-12 45.1 0.0 1.2e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP90886.1 - 6.1e-11 42.4 0.0 2.1e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP90886.1 - 1.4e-06 28.2 0.4 7.9e-05 22.4 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP90886.1 - 1.5e-06 27.6 0.1 6.6e-06 25.5 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 GAP90886.1 - 3.9e-06 25.6 1.3 4e-05 22.3 0.3 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAP90886.1 - 1.5e-05 24.3 0.0 0.00071 18.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 GAP90886.1 - 2e-05 24.7 0.3 0.023 14.8 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 GAP90886.1 - 9e-05 22.5 0.2 0.95 9.4 0.1 3.6 2 1 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 GAP90886.1 - 0.003 16.7 0.4 1.9 7.5 0.7 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.17 GAP90886.1 - 0.0042 16.4 0.1 0.026 13.8 0.3 2.1 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 GAP90886.1 - 0.0099 15.2 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 GAP90886.1 - 0.012 15.0 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 GAP90886.1 - 0.017 15.7 0.6 16 6.2 0.7 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 GAP90886.1 - 0.043 14.3 0.0 1.2 9.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.21 GAP90886.1 - 0.091 12.1 0.9 0.72 9.2 0.1 2.3 2 0 0 2 2 2 0 ThiF family HI0933_like PF03486.14 GAP90886.1 - 0.12 11.0 1.0 0.71 8.5 2.0 1.7 2 0 0 2 2 2 0 HI0933-like protein IlvN PF07991.12 GAP90886.1 - 0.18 11.3 0.6 1.5 8.3 0.2 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Zn_clus PF00172.18 GAP90887.1 - 8.3e-05 22.6 7.2 0.00025 21.1 7.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1103 PF06513.11 GAP90888.1 - 0.037 13.6 0.1 0.06 13.0 0.1 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) AAA_16 PF13191.6 GAP90889.1 - 2.7e-10 40.9 0.1 8.4e-10 39.3 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 GAP90889.1 - 1.1e-07 32.0 0.1 1.9e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 GAP90889.1 - 0.029 14.3 0.0 0.91 9.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 GAP90889.1 - 0.059 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 GAP90889.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 GAP90889.1 - 0.12 12.0 0.0 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 GAP90889.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 GAP90889.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 GAP90889.1 - 0.22 10.9 0.4 0.75 9.1 0.4 1.9 1 1 0 1 1 1 0 KaiC DUF1295 PF06966.12 GAP90890.1 - 1.5e-30 106.5 0.0 2.2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 GAP90890.1 - 3.6e-06 27.0 0.0 8.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 GAP90890.1 - 0.0014 19.0 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 GAP90890.1 - 0.004 17.5 0.0 0.01 16.2 0.0 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 GAP90890.1 - 0.06 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family VID27 PF08553.10 GAP90891.1 - 4.7e-190 631.1 0.0 6.1e-190 630.8 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 GAP90891.1 - 2.7e-75 252.0 1.3 2.7e-75 252.0 1.3 2.9 2 1 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 GAP90891.1 - 1.7e-42 144.1 1.6 3.7e-42 143.0 0.9 2.0 2 0 0 2 2 2 1 VID27 PH-like domain SDA1 PF05285.12 GAP90891.1 - 0.8 9.1 10.0 1.4 8.2 10.0 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 GAP90891.1 - 1.3 7.1 12.1 1.9 6.5 12.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 GAP90891.1 - 1.9 7.6 16.1 3.4 6.7 16.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein F-box PF00646.33 GAP90892.1 - 0.016 15.1 0.9 0.058 13.3 0.9 2.0 1 0 0 1 1 1 0 F-box domain Rsa3 PF14615.6 GAP90892.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Ribosome-assembly protein 3 F-box-like PF12937.7 GAP90892.1 - 1.7 8.6 5.7 0.9 9.5 2.2 2.4 3 1 0 3 3 3 0 F-box-like Aegerolysin PF06355.13 GAP90893.1 - 4.5e-08 33.3 0.5 8.2e-08 32.4 0.5 1.4 1 0 0 1 1 1 1 Aegerolysin GMC_oxred_N PF00732.19 GAP90894.1 - 5.2e-78 262.4 0.0 7.2e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP90894.1 - 4.4e-35 121.3 0.0 9.5e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAP90894.1 - 0.0001 21.5 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAP90894.1 - 0.0029 16.8 0.1 0.9 8.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 GAP90894.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP90894.1 - 0.011 15.0 0.0 0.028 13.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 GAP90894.1 - 0.012 15.2 1.0 0.069 12.7 0.9 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase tRNA-synt_1g PF09334.11 GAP90895.1 - 6.3e-140 466.4 0.2 4.7e-137 456.9 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 GAP90895.1 - 8.3e-09 34.2 1.2 0.0014 17.0 0.0 3.9 4 1 0 4 4 4 2 tRNA synthetases class I (I, L, M and V) DUF3987 PF13148.6 GAP90895.1 - 0.15 11.0 5.1 0.24 10.4 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AFP_2 PF18815.1 GAP90895.1 - 0.27 11.5 2.2 0.65 10.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat DUF1682 PF07946.14 GAP90895.1 - 4.1 6.5 7.5 6.7 5.8 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Zn_clus PF00172.18 GAP90897.1 - 9.1e-18 64.1 25.0 5.1e-09 36.1 6.8 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP90897.1 - 1.9e-05 23.8 0.2 3.1e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 GAP90899.1 - 2.5e-27 96.1 0.1 3.4e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP90899.1 - 3.8e-08 32.6 0.0 1.6e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 GAP90899.1 - 0.00067 18.7 0.0 0.0011 18.0 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family FAD_binding_4 PF01565.23 GAP90900.1 - 1.3e-23 83.3 0.1 2.2e-23 82.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP90900.1 - 2.8e-05 24.1 0.7 6.5e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like NOB1_Zn_bind PF08772.11 GAP90901.1 - 4.5e-32 110.0 2.7 7.7e-32 109.3 2.7 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 GAP90901.1 - 5.1e-32 110.2 0.1 2.8e-31 107.9 0.0 2.3 2 0 0 2 2 2 1 PIN domain of ribonuclease HypA PF01155.19 GAP90901.1 - 0.02 14.9 0.0 0.34 10.9 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 GAP90901.1 - 0.021 14.5 1.4 0.021 14.5 1.4 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain WRNPLPNID PF15017.6 GAP90901.1 - 0.04 14.8 5.7 0.04 14.8 5.7 2.8 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box GET2 PF08690.10 GAP90901.1 - 0.079 12.6 8.5 0.13 11.9 8.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Zn-ribbon_8 PF09723.10 GAP90901.1 - 0.87 9.8 3.0 1.1 9.4 1.4 2.0 2 0 0 2 2 2 0 Zinc ribbon domain SAPS PF04499.15 GAP90901.1 - 1.9 7.2 5.1 2.8 6.6 5.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sulfotransfer_4 PF17784.1 GAP90902.1 - 9.2e-47 159.6 0.0 1.1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain MFS_1 PF07690.16 GAP90903.1 - 3.4e-40 138.0 36.8 3.4e-40 138.0 36.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP90903.1 - 4.7e-08 31.9 4.1 7.8e-08 31.2 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP90903.1 - 1.1e-07 31.1 22.7 1.9e-07 30.3 22.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TGT PF01702.18 GAP90904.1 - 1.7e-59 201.8 0.0 2.2e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Optomotor-blind PF11078.8 GAP90904.1 - 0.0083 16.7 0.8 0.29 11.7 0.2 2.8 2 0 0 2 2 2 1 Optomotor-blind protein N-terminal region LCCL PF03815.19 GAP90905.1 - 2.5e-21 75.6 0.1 3.9e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 LCCL domain zf-SCNM1 PF15803.5 GAP90906.1 - 0.051 13.2 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 zf-C2H2_2 PF12756.7 GAP90906.1 - 2.9 8.3 7.6 24 5.3 0.0 3.5 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) Alk_phosphatase PF00245.20 GAP90908.1 - 4.8e-69 233.3 0.0 6e-68 229.7 0.0 2.0 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 GAP90908.1 - 1.3e-05 24.8 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 GAP90908.1 - 0.00094 18.9 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 GAP90908.1 - 0.0046 15.6 0.2 0.0085 14.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 GAP90908.1 - 0.079 12.0 0.4 0.12 11.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Cellulase PF00150.18 GAP90909.1 - 1.7e-51 175.3 0.0 2.1e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 GAP90909.1 - 0.022 14.2 0.1 0.46 9.9 0.1 2.3 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel PLDc_2 PF13091.6 GAP90910.1 - 3e-14 53.1 0.0 2.4e-06 27.4 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAP90910.1 - 7.5e-07 29.1 6.6 0.017 15.3 0.1 3.8 3 1 0 3 3 3 2 Phospholipase D Active site motif DnaG_DnaB_bind PF08278.11 GAP90910.1 - 0.056 14.0 0.0 0.59 10.7 0.0 2.1 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding NDUFA12 PF05071.16 GAP90911.1 - 7.1e-30 103.7 3.9 9.2e-30 103.4 3.9 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TRAP_alpha PF03896.16 GAP90912.1 - 0.00031 20.0 3.0 0.00055 19.2 3.0 1.4 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 GAP90912.1 - 0.01 14.0 29.1 0.013 13.6 29.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cytomega_UL84 PF06284.11 GAP90912.1 - 0.029 12.8 4.3 0.048 12.1 4.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF4834 PF16118.5 GAP90912.1 - 0.032 15.2 0.0 0.28 12.2 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Nop14 PF04147.12 GAP90912.1 - 3.6 5.7 26.2 4.8 5.3 26.2 1.0 1 0 0 1 1 1 0 Nop14-like family p450 PF00067.22 GAP90913.1 - 1.1e-52 179.3 0.0 1.5e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 GAP90915.1 - 6.3e-25 88.0 0.0 4.8e-24 85.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP90915.1 - 7.8e-14 51.6 0.1 3.2e-12 46.3 0.1 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Gpr1_Fun34_YaaH PF01184.19 GAP90917.1 - 1.5e-30 106.3 17.4 1.9e-30 106.0 17.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2545 PF10810.8 GAP90917.1 - 0.019 15.1 4.5 0.059 13.5 4.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) adh_short_C2 PF13561.6 GAP90918.1 - 2.5e-58 197.4 3.5 3e-58 197.2 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP90918.1 - 9.1e-43 146.0 3.7 1.2e-42 145.6 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP90918.1 - 5.5e-16 59.0 2.0 7.5e-16 58.6 2.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP90918.1 - 0.0015 18.0 1.3 0.0034 16.9 1.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 GAP90918.1 - 0.0068 15.9 0.4 0.011 15.1 0.4 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YAcAr PF10686.9 GAP90918.1 - 0.013 15.5 2.3 0.019 14.9 0.6 2.2 2 1 1 3 3 3 0 YspA, cpYpsA-related SLOG family Sacchrp_dh_NADP PF03435.18 GAP90918.1 - 0.028 14.7 0.2 0.055 13.7 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AIRC PF00731.20 GAP90918.1 - 0.051 13.1 1.3 0.083 12.5 0.2 1.9 2 0 0 2 2 2 0 AIR carboxylase Glyco_tranf_2_3 PF13641.6 GAP90918.1 - 0.058 13.3 0.2 0.098 12.5 0.2 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_trans_4_4 PF13579.6 GAP90918.1 - 0.066 13.6 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain GDP_Man_Dehyd PF16363.5 GAP90918.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_transf_4 PF13439.6 GAP90918.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Biotin_carb_N PF00289.22 GAP90918.1 - 0.16 12.5 2.8 3.3 8.3 0.4 2.4 1 1 1 2 2 2 0 Biotin carboxylase, N-terminal domain FAD_binding_3 PF01494.19 GAP90919.1 - 2.3e-21 76.4 0.0 3e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP90919.1 - 7.3e-14 52.1 1.0 1.2e-07 31.7 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP90919.1 - 2.5e-06 26.9 0.2 0.011 15.0 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP90919.1 - 5.9e-05 22.3 0.8 0.00011 21.5 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 GAP90919.1 - 0.00016 20.5 0.9 0.0042 15.8 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 GAP90919.1 - 0.00018 21.7 0.6 0.00047 20.3 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAP90919.1 - 0.00028 20.1 0.1 0.00068 18.8 0.1 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein SE PF08491.10 GAP90919.1 - 0.00075 18.6 0.1 0.004 16.3 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase FAD_oxidored PF12831.7 GAP90919.1 - 0.0011 18.5 0.5 0.0017 17.8 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAP90919.1 - 0.0045 16.3 0.3 0.0067 15.7 0.3 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 GAP90919.1 - 0.005 16.0 0.1 0.008 15.3 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 GAP90919.1 - 0.0089 16.6 0.2 8.3 7.0 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 GAP90919.1 - 0.039 13.2 0.3 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 GAP90919.1 - 0.073 11.9 0.3 0.93 8.3 0.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 GAP90919.1 - 0.28 10.4 0.6 1.1 8.5 0.6 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cep57_CLD_2 PF14197.6 GAP90920.1 - 0.00032 20.7 3.1 0.00091 19.3 3.1 1.7 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 NRBF2 PF08961.10 GAP90920.1 - 0.00075 19.2 1.1 0.0027 17.3 0.4 2.0 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 GAP90920.1 - 0.0035 17.9 0.1 0.0064 17.1 0.1 1.5 1 0 0 1 1 1 1 Initiation control protein YabA ZapB PF06005.12 GAP90920.1 - 0.0074 16.7 0.1 0.017 15.5 0.1 1.6 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 GAP90920.1 - 0.023 14.5 0.9 0.061 13.1 0.9 1.6 1 0 0 1 1 1 0 Septum formation initiator PikAIV_N PF18605.1 GAP90920.1 - 0.024 14.2 4.9 0.052 13.1 4.9 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TSC22 PF01166.18 GAP90920.1 - 0.025 14.9 0.3 0.056 13.8 0.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4201 PF13870.6 GAP90920.1 - 0.071 12.8 1.4 0.15 11.8 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) CENP-H PF05837.12 GAP90920.1 - 0.32 11.4 2.1 0.44 11.0 0.7 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 GAP90922.1 - 0.016 15.6 0.3 0.047 14.1 0.3 1.7 1 0 0 1 1 1 0 Cell division protein ZapB SPX PF03105.19 GAP90922.1 - 0.021 14.7 2.5 0.029 14.3 2.5 1.3 1 0 0 1 1 1 0 SPX domain APG6_N PF17675.1 GAP90922.1 - 0.037 14.6 1.5 0.11 13.0 1.5 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region HAP1_N PF04849.13 GAP90922.1 - 0.04 13.1 0.7 0.075 12.2 0.7 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Filament PF00038.21 GAP90922.1 - 0.074 12.6 1.0 0.12 12.0 0.2 1.7 2 0 0 2 2 2 0 Intermediate filament protein SlyX PF04102.12 GAP90922.1 - 0.12 13.1 1.2 0.36 11.5 1.2 1.8 1 0 0 1 1 1 0 SlyX bZIP_2 PF07716.15 GAP90922.1 - 0.12 12.4 3.5 0.44 10.7 1.0 2.5 2 0 0 2 2 2 0 Basic region leucine zipper KIAA1430 PF13879.6 GAP90922.1 - 0.13 13.0 2.3 0.34 11.7 2.3 1.8 1 0 0 1 1 1 0 KIAA1430 homologue DUF2312 PF10073.9 GAP90922.1 - 0.17 11.6 1.8 0.38 10.4 1.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Cep57_CLD_2 PF14197.6 GAP90922.1 - 0.22 11.6 3.9 0.14 12.3 1.0 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 CCDC106 PF15794.5 GAP90922.1 - 0.23 11.1 3.2 0.36 10.5 3.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 NYD-SP28_assoc PF14775.6 GAP90922.1 - 0.25 11.5 1.4 0.57 10.3 1.4 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain Syntaxin_2 PF14523.6 GAP90922.1 - 0.29 11.5 2.8 2 8.8 0.6 2.8 3 0 0 3 3 3 0 Syntaxin-like protein Ndc1_Nup PF09531.10 GAP90922.1 - 1.7 7.2 4.6 2.3 6.8 4.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup YabA PF06156.13 GAP90922.1 - 2 9.1 4.2 0.83 10.3 0.4 2.3 3 0 0 3 3 2 0 Initiation control protein YabA Fzo_mitofusin PF04799.13 GAP90922.1 - 2.2 7.8 3.9 4.5 6.8 1.0 2.6 2 1 1 3 3 3 0 fzo-like conserved region DUF1688 PF07958.11 GAP90924.1 - 1.1e-178 594.3 0.0 1.3e-178 594.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) 60KD_IMP PF02096.20 GAP90925.1 - 2.8e-12 46.8 1.0 5.3e-12 45.9 1.0 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein TOM13 PF08219.11 GAP90926.1 - 1.2e-35 121.3 0.0 1.5e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.13 GAP90927.1 - 6.1e-23 81.2 0.2 1.2e-22 80.2 0.0 1.6 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.6 GAP90927.1 - 1.3e-11 44.1 2.8 2.3e-11 43.3 2.8 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 GAP90927.1 - 2.3e-10 40.5 0.0 4.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 GAP90927.1 - 0.04 13.5 0.2 0.068 12.8 0.2 1.3 1 0 0 1 1 1 0 TAP C-terminal domain Cwf_Cwc_15 PF04889.12 GAP90927.1 - 0.051 13.3 2.1 0.086 12.6 2.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 GAP90927.1 - 1.2 8.5 17.5 0.046 13.2 8.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) TFIIE-A_C PF11521.8 GAP90927.1 - 4.4 7.7 5.5 7.5 6.9 2.6 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF1524 PF07510.11 GAP90928.1 - 4.4e-08 33.1 0.0 5.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Gtr1_RagA PF04670.12 GAP90929.1 - 9.2e-95 316.4 0.2 1.2e-94 316.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 GAP90929.1 - 5.5e-09 36.3 0.2 1.5e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAP90929.1 - 1.2e-08 34.7 0.1 2.1e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 GAP90929.1 - 4.6e-08 32.7 0.2 7.4e-08 32.0 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 GAP90929.1 - 9.6e-08 32.1 0.0 2.3e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAP90929.1 - 0.00094 18.4 4.2 0.14 11.3 0.9 2.7 2 1 1 3 3 3 2 G-protein alpha subunit DUF815 PF05673.13 GAP90929.1 - 0.0016 17.6 0.1 0.0039 16.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 GAP90929.1 - 0.0022 17.7 0.7 0.038 13.7 0.3 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 GAP90929.1 - 0.003 18.1 0.2 0.0061 17.1 0.2 1.9 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 GAP90929.1 - 0.0034 17.3 1.1 0.13 12.2 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase DAP3 PF10236.9 GAP90929.1 - 0.071 12.3 1.3 0.12 11.5 0.9 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Sigma54_activat PF00158.26 GAP90929.1 - 0.097 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Lipase_GDSL_2 PF13472.6 GAP90931.1 - 3.5e-07 30.8 1.8 4.8e-07 30.4 1.8 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP90931.1 - 0.0074 16.3 0.1 0.016 15.2 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Opi1 PF08618.10 GAP90932.1 - 3.1e-39 135.4 14.2 8.6e-29 101.0 0.0 3.9 3 1 1 4 4 4 3 Transcription factor Opi1 Perilipin PF03036.16 GAP90932.1 - 1 8.3 3.1 0.83 8.6 0.3 2.0 2 1 1 3 3 3 0 Perilipin family Adap_comp_sub PF00928.21 GAP90933.1 - 1.8e-91 306.2 0.0 3.2e-91 305.4 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAP90933.1 - 7e-09 35.8 0.2 1.1e-08 35.1 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 GAP90933.1 - 0.17 11.3 0.0 0.72 9.2 0.0 1.9 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain HET PF06985.11 GAP90934.1 - 6.1e-11 42.9 3.2 1.3e-07 32.1 0.1 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 GAP90935.1 - 4.1e-49 167.0 0.0 6.2e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAP90935.1 - 2.8e-09 36.9 9.3 0.00026 21.3 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Rop PF01815.16 GAP90935.1 - 0.00038 20.3 0.5 0.0012 18.6 0.5 1.9 1 0 0 1 1 1 1 Rop protein FOXP-CC PF16159.5 GAP90935.1 - 0.0023 18.5 5.1 0.025 15.2 1.6 2.8 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 GAP90935.1 - 0.13 13.2 15.5 0.31 12.0 0.7 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAP90935.1 - 2.5 8.7 11.6 0.15 12.5 0.7 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Lactamase_B PF00753.27 GAP90936.1 - 2.7e-06 27.5 2.7 1.6e-05 25.0 2.3 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 GAP90936.1 - 0.0036 16.8 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CMD PF02627.20 GAP90937.1 - 1.7e-07 31.2 0.1 4e-07 30.0 0.1 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family A_thal_3526 PF09713.10 GAP90937.1 - 0.2 11.9 0.1 3.9 7.8 0.3 2.3 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) MFS_1 PF07690.16 GAP90938.1 - 4.3e-37 127.8 26.2 5.8e-37 127.4 26.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 GAP90938.1 - 0.15 10.3 9.2 0.27 9.5 5.3 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CMD PF02627.20 GAP90939.1 - 1.1e-19 70.2 0.1 2.3e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TFX_C PF14601.6 GAP90939.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term ADH_zinc_N PF00107.26 GAP90940.1 - 4.6e-07 29.9 0.1 1e-06 28.7 0.1 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP90940.1 - 1.4e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Lactamase_B_2 PF12706.7 GAP90941.1 - 0.00043 19.8 0.1 0.0011 18.6 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 GAP90941.1 - 0.0097 15.9 7.6 0.17 11.8 7.6 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Serglycin PF04360.12 GAP90941.1 - 2.4 8.1 4.1 3.9 7.4 4.1 1.2 1 0 0 1 1 1 0 Serglycin NAD_binding_11 PF14833.6 GAP90942.1 - 9.4e-23 80.8 0.1 1.8e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 GAP90942.1 - 5.1e-12 46.3 0.1 9.7e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.16 GAP90943.1 - 1.8e-30 106.1 31.6 1.8e-30 106.1 31.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP90943.1 - 3.6e-09 36.0 9.6 3.6e-09 36.0 9.6 2.5 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAP90943.1 - 0.014 13.8 2.9 0.023 13.1 2.9 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF5325 PF17259.2 GAP90943.1 - 3.7 7.5 8.4 0.31 10.9 0.9 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5325) tRNA_int_endo PF01974.17 GAP90944.1 - 2e-17 63.0 0.0 3.7e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 GAP90944.1 - 5.8e-08 32.3 0.0 9.3e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain tRNA_int_end_N2 PF12928.7 GAP90944.1 - 0.025 14.8 0.0 9 6.6 0.0 3.5 3 1 0 3 3 3 0 tRNA-splicing endonuclease subunit sen54 N-term Glyco_transf_21 PF13506.6 GAP90945.1 - 8.9e-11 41.6 0.1 0.00017 21.1 0.0 3.5 2 1 1 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 GAP90945.1 - 1.4e-05 25.1 0.0 0.00024 21.1 0.0 2.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAP90945.1 - 0.00038 20.3 0.0 0.077 12.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 RasGAP PF00616.19 GAP90946.1 - 0.06 13.0 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase tRNA-synt_1c PF00749.21 GAP90947.1 - 7.2e-104 347.1 0.0 9.8e-104 346.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 GAP90947.1 - 2.9e-39 134.7 0.1 7.6e-39 133.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 GAP90947.1 - 0.012 15.0 0.2 0.031 13.6 0.1 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain PPR_1 PF12854.7 GAP90947.1 - 0.15 11.8 0.1 0.41 10.4 0.1 1.8 1 0 0 1 1 1 0 PPR repeat Ribosomal_L1 PF00687.21 GAP90948.1 - 8.6e-20 71.3 0.0 1.2e-19 70.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family STAG PF08514.11 GAP90948.1 - 0.096 12.6 1.1 0.17 11.8 1.1 1.4 1 0 0 1 1 1 0 STAG domain COG2 PF06148.11 GAP90949.1 - 2.3e-24 86.0 0.0 3.3e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 GAP90949.1 - 0.0023 18.0 0.0 0.0086 16.1 0.0 2.0 3 0 0 3 3 3 1 Vps51/Vps67 Hap4_Hap_bind PF10297.9 GAP90950.1 - 1.3e-08 34.6 6.9 1.3e-08 34.6 6.9 2.8 4 0 0 4 4 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 GAP90950.1 - 7.4e-05 22.8 16.4 0.014 15.5 16.6 2.8 1 1 0 1 1 1 1 bZIP transcription factor HAP1_N PF04849.13 GAP90950.1 - 0.00013 21.3 8.7 0.0002 20.7 8.7 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Spc7 PF08317.11 GAP90950.1 - 0.0023 16.9 8.1 0.0037 16.2 8.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-C4H2 PF10146.9 GAP90950.1 - 0.0041 17.4 5.5 0.0041 17.4 5.5 2.4 2 1 0 2 2 2 1 Zinc finger-containing protein ATG16 PF08614.11 GAP90950.1 - 0.0063 16.8 8.6 0.014 15.7 8.6 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMPIT PF07851.13 GAP90950.1 - 0.014 14.6 3.3 0.021 14.1 3.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4618 PF15397.6 GAP90950.1 - 0.021 14.2 3.7 0.036 13.5 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CortBP2 PF09727.9 GAP90950.1 - 0.029 14.3 11.1 0.15 12.0 8.8 2.3 2 0 0 2 2 2 0 Cortactin-binding protein-2 Exonuc_VII_L PF02601.15 GAP90950.1 - 0.041 13.4 1.4 0.06 12.9 1.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Not3 PF04065.15 GAP90950.1 - 0.046 13.2 4.4 0.084 12.3 4.4 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component YlqD PF11068.8 GAP90950.1 - 0.051 14.0 5.6 0.043 14.2 4.1 1.6 1 1 0 1 1 1 0 YlqD protein Sec34 PF04136.15 GAP90950.1 - 0.06 13.2 2.0 0.11 12.4 2.0 1.3 1 0 0 1 1 1 0 Sec34-like family Glutaredoxin2_C PF04399.13 GAP90950.1 - 0.063 13.1 1.0 0.13 12.1 1.0 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain HMMR_N PF15905.5 GAP90950.1 - 0.072 12.5 9.5 0.13 11.7 9.5 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Baculo_PEP_C PF04513.12 GAP90950.1 - 0.082 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 GAP90950.1 - 0.11 11.1 3.1 0.16 10.5 3.1 1.2 1 0 0 1 1 1 0 AAA domain DUF1043 PF06295.12 GAP90950.1 - 0.13 12.2 3.1 0.28 11.2 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) YabA PF06156.13 GAP90950.1 - 0.14 12.8 4.3 0.41 11.3 4.2 1.8 1 1 0 1 1 1 0 Initiation control protein YabA DUF1664 PF07889.12 GAP90950.1 - 0.15 12.1 0.9 0.27 11.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IFT20 PF14931.6 GAP90950.1 - 0.24 11.6 7.8 0.51 10.5 7.8 1.6 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 TolA_bind_tri PF16331.5 GAP90950.1 - 0.32 11.1 10.9 0.8 9.8 10.9 1.7 1 1 0 1 1 1 0 TolA binding protein trimerisation DUF16 PF01519.16 GAP90950.1 - 0.32 11.5 3.5 0.64 10.5 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fmp27_WPPW PF10359.9 GAP90950.1 - 0.78 8.5 6.3 1.1 8.0 6.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.6 GAP90950.1 - 1 8.7 4.3 2 7.7 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TEX13 PF15186.6 GAP90950.1 - 1.4 8.6 6.0 2.6 7.7 6.0 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family 5_nucleotid PF05761.14 GAP90950.1 - 2.7 6.8 6.2 3.7 6.4 6.2 1.1 1 0 0 1 1 1 0 5' nucleotidase family FapA PF03961.13 GAP90950.1 - 3 6.4 4.3 4.5 5.8 4.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 GAP90950.1 - 3.2 7.8 10.0 7 6.7 10.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 GAP90950.1 - 3.3 7.8 17.4 1.3 9.1 12.9 2.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 GAP90950.1 - 3.6 7.8 20.5 0.6 10.2 14.4 2.5 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 GAP90950.1 - 4.6 7.8 16.0 0.96 10.0 9.2 2.4 1 1 1 2 2 2 0 bZIP Maf transcription factor HIP1_clath_bdg PF16515.5 GAP90950.1 - 6.8 7.4 14.4 0.84 10.3 10.1 1.7 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 GAP90950.1 - 7.9 6.3 7.3 13 5.7 5.6 2.2 1 1 1 2 2 2 0 Septum formation initiator Acetyltransf_1 PF00583.25 GAP90951.1 - 0.00024 21.3 0.1 0.0007 19.8 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP90951.1 - 0.0003 21.2 0.0 0.00072 19.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAP90951.1 - 0.009 15.9 0.1 0.051 13.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP90951.1 - 0.054 13.6 0.0 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Bac_DNA_binding PF00216.21 GAP90951.1 - 0.061 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial DNA-binding protein FR47 PF08445.10 GAP90951.1 - 0.12 12.4 0.1 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein AA_permease_2 PF13520.6 GAP90952.1 - 3.2e-41 141.6 51.4 4e-41 141.2 51.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP90952.1 - 2e-23 82.7 46.9 2.5e-23 82.4 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 GAP90952.1 - 0.19 11.6 0.3 0.61 9.9 0.3 1.9 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Glyco_hydro_61 PF03443.14 GAP90953.1 - 4.4e-56 190.1 0.0 7.1e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 GAP90953.1 - 2.8e-12 46.4 8.3 2.8e-12 46.4 8.3 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain NPCBM_assoc PF10633.9 GAP90953.1 - 0.044 14.0 2.4 0.64 10.3 0.0 3.2 4 0 0 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase MFS_1 PF07690.16 GAP90954.1 - 7.4e-47 160.0 53.4 7.4e-47 160.0 53.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_64 PF16483.5 GAP90955.1 - 2.3e-122 408.8 0.1 2.7e-122 408.6 0.1 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Iso_dh PF00180.20 GAP90957.1 - 1.2e-87 294.4 0.0 1.3e-87 294.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase 4HBT PF03061.22 GAP90958.1 - 2.6e-05 24.5 0.0 4.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily ABC_membrane PF00664.23 GAP90959.1 - 5e-82 275.6 43.1 4.1e-43 148.0 15.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAP90959.1 - 3.8e-67 225.0 0.0 5.2e-33 114.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAP90959.1 - 5.7e-17 61.9 2.2 0.00021 20.8 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 GAP90959.1 - 1.2e-08 35.4 0.0 0.015 15.6 0.0 3.3 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 GAP90959.1 - 3.6e-07 29.3 0.6 0.018 13.9 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 GAP90959.1 - 7.6e-07 29.2 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAP90959.1 - 1.2e-06 28.2 1.3 0.0016 18.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAP90959.1 - 1.3e-06 28.9 0.8 0.099 13.0 0.1 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 GAP90959.1 - 1.6e-06 28.0 0.3 0.053 13.2 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 GAP90959.1 - 2.4e-06 28.2 0.7 0.012 16.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 GAP90959.1 - 3.6e-06 27.0 0.1 0.04 13.7 0.1 2.8 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 GAP90959.1 - 5.9e-06 26.2 0.2 0.028 14.1 0.1 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 GAP90959.1 - 3.3e-05 23.6 0.0 0.095 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 GAP90959.1 - 4.4e-05 23.3 0.1 0.071 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 GAP90959.1 - 0.00012 22.5 1.0 1.4 9.3 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 GAP90959.1 - 0.00024 20.9 0.0 0.21 11.2 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 GAP90959.1 - 0.00059 20.0 0.1 1.1 9.5 0.0 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 GAP90959.1 - 0.00096 19.7 0.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 GAP90959.1 - 0.0012 18.4 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 GAP90959.1 - 0.002 18.1 0.0 0.45 10.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 GAP90959.1 - 0.0022 18.0 0.1 2.5 8.1 0.0 3.2 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 GAP90959.1 - 0.0042 17.4 0.1 6.6 7.1 0.0 3.3 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 GAP90959.1 - 0.0067 16.2 0.4 14 5.4 0.0 3.9 3 1 0 3 3 3 0 DEAD/DEAH box helicase PRK PF00485.18 GAP90959.1 - 0.011 15.5 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 GAP90959.1 - 0.013 14.7 1.0 5.7 6.1 0.0 3.0 2 1 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 GAP90959.1 - 0.013 15.5 0.0 15 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 GAP90959.1 - 0.026 14.5 0.1 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 GAP90959.1 - 0.028 14.8 0.0 14 6.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 GAP90959.1 - 0.037 14.3 0.0 5.3 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 GAP90959.1 - 0.038 13.7 1.2 30 4.3 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_33 PF13671.6 GAP90959.1 - 0.067 13.4 0.2 3.8 7.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 GAP90959.1 - 0.075 12.8 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TniB PF05621.11 GAP90959.1 - 0.092 12.2 0.1 17 4.8 0.0 3.2 4 0 0 4 4 3 0 Bacterial TniB protein MMR_HSR1 PF01926.23 GAP90959.1 - 0.11 12.6 0.1 36 4.5 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_11 PF13086.6 GAP90959.1 - 0.12 12.2 0.0 19 5.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 GAP90959.1 - 0.13 12.4 0.1 0.9 9.6 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain ATPase PF06745.13 GAP90959.1 - 0.18 11.1 0.9 4.8 6.5 0.1 2.8 3 0 0 3 3 3 0 KaiC Zeta_toxin PF06414.12 GAP90959.1 - 0.19 11.0 0.8 25 4.1 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin FSH1 PF03959.13 GAP90960.1 - 4.3e-30 105.0 0.0 8.8e-30 103.9 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 GAP90961.1 - 2.2e-73 247.0 0.0 4.9e-73 245.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP90961.1 - 2.3e-61 206.8 0.2 7.4e-61 205.2 0.2 2.0 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 GAP90961.1 - 1.5e-49 169.3 0.0 3e-49 168.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAP90961.1 - 3.2e-48 164.5 0.0 5.2e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAP90961.1 - 2.8e-38 130.6 0.0 1.4e-37 128.3 0.0 2.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAP90961.1 - 4.3e-18 65.8 0.0 1.2e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAP90961.1 - 2.6e-16 59.6 0.2 2.6e-16 59.6 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 GAP90961.1 - 5e-14 53.5 0.0 2.9e-13 51.0 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAP90961.1 - 8.5e-13 48.4 2.3 1.1e-12 48.1 0.0 2.4 3 0 0 3 3 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 GAP90961.1 - 2.2e-10 40.5 0.2 1.3e-09 38.0 0.1 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 GAP90961.1 - 3.7e-07 30.0 0.2 3.7e-07 30.0 0.2 2.5 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 GAP90961.1 - 4.3e-05 23.8 0.3 0.0001 22.6 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 GAP90961.1 - 0.00051 19.5 0.2 0.0012 18.3 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 GAP90961.1 - 0.048 13.0 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 GAP90961.1 - 0.07 12.7 0.3 0.15 11.6 0.3 1.5 1 0 0 1 1 1 0 NmrA-like family Phytase PF02333.15 GAP90962.1 - 3.4e-55 187.6 4.6 9e-54 182.9 1.0 2.2 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 GAP90962.1 - 5e-05 23.6 28.7 0.033 14.5 15.5 2.5 2 0 0 2 2 2 2 EGF-like domain AA_permease PF00324.21 GAP90963.1 - 3.6e-106 355.6 42.7 4.4e-106 355.3 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP90963.1 - 5.1e-26 91.5 43.3 6.4e-26 91.1 43.3 1.1 1 0 0 1 1 1 1 Amino acid permease Aldo_ket_red PF00248.21 GAP90964.1 - 1e-76 257.9 0.0 1.2e-76 257.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4470 PF14737.6 GAP90965.1 - 4.4e-24 84.5 0.0 9.6e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 GAP90965.1 - 8.6e-09 35.4 10.4 2.5e-08 33.9 10.4 1.8 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 GAP90965.1 - 0.085 13.2 4.0 0.19 12.0 4.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Transp_cyt_pur PF02133.15 GAP90966.1 - 1.3e-31 109.9 28.3 2.3e-31 109.1 28.3 1.4 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 GAP90967.1 - 2.4e-44 151.7 36.0 2.4e-44 151.7 36.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP90967.1 - 3.4e-10 39.4 28.8 3.8e-09 35.9 28.8 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 GAP90967.1 - 0.0044 15.5 7.7 0.0072 14.8 7.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UL42 PF17638.2 GAP90967.1 - 0.27 11.2 3.7 0.96 9.4 0.1 2.8 2 1 0 2 2 2 0 HCMV UL42 DUF3040 PF11239.8 GAP90967.1 - 2 8.8 0.0 2 8.8 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) OATP PF03137.20 GAP90967.1 - 5.5 5.2 14.8 8.4 4.5 0.2 3.5 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SGL PF08450.12 GAP90968.1 - 0.00051 19.7 0.0 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Phage_capsid PF05065.13 GAP90969.1 - 1.5 8.0 5.9 0.41 9.9 2.8 1.6 2 0 0 2 2 2 0 Phage capsid family zf-FPG_IleRS PF06827.14 GAP90970.1 - 0.0091 15.8 0.7 4.3 7.3 0.0 2.2 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS DNA_primase_lrg PF04104.14 GAP90971.1 - 2.6e-81 273.0 0.0 3.5e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Clr5 PF14420.6 GAP90972.1 - 2.5e-19 69.2 0.6 9e-19 67.5 0.6 2.0 1 0 0 1 1 1 1 Clr5 domain TPR_8 PF13181.6 GAP90972.1 - 0.021 15.0 0.0 0.059 13.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat FMO-like PF00743.19 GAP90974.1 - 1.9e-13 49.7 0.0 3.1e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAP90974.1 - 8.1e-09 35.1 0.0 2.1e-07 30.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 GAP90974.1 - 6.6e-08 32.7 0.0 1.5e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP90974.1 - 1.1e-07 31.4 0.0 2.4e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP90974.1 - 1.3e-06 28.0 0.0 6.6e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP90974.1 - 0.00041 20.4 0.7 0.043 13.8 0.0 3.1 2 1 1 3 3 3 1 FAD-NAD(P)-binding Pkinase PF00069.25 GAP90975.1 - 2.8e-43 148.2 0.0 4.9e-42 144.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP90975.1 - 9.8e-26 90.6 0.0 2.9e-25 89.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP90975.1 - 0.019 13.7 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 GAP90975.1 - 6.6 5.6 7.3 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain FAD_binding_3 PF01494.19 GAP90976.1 - 1.2e-06 28.1 1.5 3.1e-05 23.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Ank_2 PF12796.7 GAP90977.1 - 2.2e-20 73.0 0.3 5.6e-10 39.7 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP90977.1 - 2.3e-19 69.5 0.2 2.8e-06 27.8 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP90977.1 - 3.2e-19 67.0 0.2 0.019 15.5 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat CorA PF01544.18 GAP90977.1 - 7.3e-18 64.9 0.0 1.2e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ank_5 PF13857.6 GAP90977.1 - 2.7e-14 53.0 0.7 5.1e-06 26.6 0.1 4.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAP90977.1 - 4.4e-14 52.2 0.4 0.016 15.7 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat DUF1843 PF08898.10 GAP90977.1 - 0.00026 21.4 1.1 0.0018 18.7 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1843) DUF2207 PF09972.9 GAP90977.1 - 0.001 17.9 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) 2TM PF13239.6 GAP90977.1 - 1.3 9.4 3.7 3.1 8.1 3.7 1.6 1 0 0 1 1 1 0 2TM domain PBP1_TM PF14812.6 GAP90978.1 - 0.13 12.7 0.4 5.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.7 GAP90979.1 - 5.4e-29 100.6 0.2 2.3e-09 37.7 0.1 4.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP90979.1 - 7.1e-28 96.6 4.3 3.9e-08 33.7 0.0 6.1 2 1 5 8 8 8 6 Ankyrin repeats (many copies) SPX PF03105.19 GAP90979.1 - 1.5e-21 77.8 16.4 3.8e-09 37.0 1.8 3.1 1 1 2 3 3 3 3 SPX domain Ank_5 PF13857.6 GAP90979.1 - 3.2e-18 65.6 5.9 4.3e-05 23.7 0.1 6.3 2 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP90979.1 - 1.5e-17 61.8 7.6 0.0039 17.6 0.0 6.4 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 GAP90979.1 - 2.1e-15 56.4 5.8 0.0018 18.7 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat GDPD PF03009.17 GAP90979.1 - 3.5e-09 36.8 0.0 3.9e-08 33.3 0.0 2.7 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Rsa3 PF14615.6 GAP90979.1 - 0.062 12.9 0.9 3.2 7.4 0.1 3.0 3 0 0 3 3 3 0 Ribosome-assembly protein 3 p450 PF00067.22 GAP90980.1 - 1.1e-65 222.2 0.0 1.5e-65 221.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CUE PF02845.16 GAP90981.1 - 8.4e-11 41.4 0.0 1.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain HA2 PF04408.23 GAP90982.1 - 3.8e-17 62.5 0.1 8e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 GAP90982.1 - 1.6e-15 57.2 0.0 3.4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 GAP90982.1 - 2.5e-12 47.1 0.0 5.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 GAP90982.1 - 0.00032 21.0 0.0 0.00076 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 GAP90982.1 - 0.0076 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAP90982.1 - 0.0081 16.5 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 GAP90982.1 - 0.035 13.7 0.3 0.52 9.9 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 GAP90982.1 - 0.15 11.1 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 GAP90982.1 - 0.19 12.2 0.0 0.44 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 GAP90982.1 - 0.38 10.0 1.5 0.92 8.7 0.1 2.3 2 1 1 3 3 3 0 Zeta toxin SKG6 PF08693.10 GAP90983.1 - 0.18 11.2 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2905 PF11146.8 GAP90983.1 - 0.56 10.4 1.9 34 4.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) SKG6 PF08693.10 GAP90984.1 - 2.1e-12 46.2 0.6 7.8e-12 44.4 0.6 2.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 GAP90984.1 - 0.025 14.2 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4381 PF14316.6 GAP90984.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CcmD PF04995.14 GAP90984.1 - 0.16 12.1 0.7 0.26 11.4 0.7 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Gram_pos_anchor PF00746.21 GAP90984.1 - 0.18 11.8 1.3 0.51 10.3 0.1 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Utp14 PF04615.13 GAP90984.1 - 7.3 5.0 9.2 9.7 4.6 9.2 1.2 1 0 0 1 1 1 0 Utp14 protein COesterase PF00135.28 GAP90985.1 - 1e-76 258.9 0.0 1.4e-76 258.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP90985.1 - 1.5e-06 28.2 0.2 3.8e-06 26.9 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DASH_Dad2 PF08654.10 GAP90987.1 - 1.9e-31 108.4 0.7 2.7e-31 107.9 0.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 CENP-Q PF13094.6 GAP90987.1 - 0.022 15.0 0.6 0.022 15.0 0.6 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DASH_Duo1 PF08651.10 GAP90987.1 - 0.035 13.9 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 Fzo_mitofusin PF04799.13 GAP90987.1 - 0.053 13.1 0.1 0.075 12.6 0.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region Seryl_tRNA_N PF02403.22 GAP90987.1 - 0.074 13.3 0.3 0.074 13.3 0.3 1.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Shugoshin_N PF07558.11 GAP90988.1 - 1.9e-18 66.0 8.2 4.7e-18 64.8 8.2 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 GAP90988.1 - 1.5e-10 40.7 3.7 8.3e-10 38.3 3.7 2.5 1 0 0 1 1 1 1 Shugoshin C terminus TMCO5 PF14992.6 GAP90988.1 - 1.5 8.3 7.8 0.17 11.4 1.9 2.0 2 0 0 2 2 2 0 TMCO5 family Metallophos_2 PF12850.7 GAP90989.1 - 8.4e-12 45.6 0.0 1.1e-11 45.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 GAP90989.1 - 0.18 12.3 0.0 2.5 8.6 0.0 2.1 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Aminotran_5 PF00266.19 GAP90990.1 - 3.8e-28 98.5 0.0 4.8e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V CRM1_C PF08767.11 GAP90991.1 - 3.5e-128 427.3 1.2 3.5e-128 427.3 1.2 2.9 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 GAP90991.1 - 2e-40 138.3 10.1 9.5e-40 136.1 6.7 3.7 2 1 1 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 GAP90991.1 - 3.7e-33 113.0 4.9 1.1e-32 111.5 4.9 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 GAP90991.1 - 9.9e-28 96.0 1.2 9.9e-28 96.0 1.2 2.9 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 GAP90991.1 - 3.5e-19 68.0 3.6 5.2e-19 67.5 1.4 2.3 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 GAP90991.1 - 1.8e-14 53.4 0.6 9.2e-14 51.1 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 GAP90991.1 - 0.047 14.3 1.8 3.8 8.2 0.1 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 GAP90991.1 - 0.28 11.1 5.0 0.27 11.1 0.1 3.5 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) MMS19_C PF12460.8 GAP90991.1 - 0.78 8.8 8.9 1.2 8.1 0.0 4.0 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal Fungal_trans_2 PF11951.8 GAP90992.1 - 3.6e-33 114.9 0.5 4.4e-33 114.6 0.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain IQCJ-SCHIP1 PF15157.6 GAP90992.1 - 0.0027 17.6 0.1 0.0055 16.6 0.1 1.5 1 0 0 1 1 1 1 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF2730 PF10805.8 GAP90992.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SR-25 PF10500.9 GAP90992.1 - 1.9 8.0 8.7 3.2 7.3 8.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NAD_binding_10 PF13460.6 GAP90993.1 - 7.5e-26 91.1 0.1 1.3e-25 90.3 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAP90993.1 - 1.3e-25 90.3 0.0 1.6e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Abhydrolase_3 PF07859.13 GAP90994.1 - 1.3e-19 70.9 0.0 1.7e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 GAP90994.1 - 3e-15 56.0 0.0 3.6e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Aldolase_II PF00596.21 GAP90997.1 - 4.4e-42 144.1 0.6 5.7e-42 143.8 0.6 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Cpn60_TCP1 PF00118.24 GAP90998.1 - 3.1e-172 573.6 0.9 3.5e-172 573.4 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 GAP90998.1 - 0.04 13.5 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 BRK domain DUF1168 PF06658.12 GAP90999.1 - 1.3e-30 106.0 13.7 1.5e-30 105.8 12.4 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1168) GGN PF15685.5 GAP90999.1 - 0.17 10.9 11.4 0.32 10.0 11.4 1.4 1 1 0 1 1 1 0 Gametogenetin Chorion_3 PF05387.11 GAP90999.1 - 2.5 7.7 10.1 1.2 8.7 7.5 1.6 2 0 0 2 2 2 0 Chorion family 3 His_Phos_1 PF00300.22 GAP91000.1 - 4.4e-28 98.3 0.0 8.6e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EcKinase PF02958.20 GAP91002.1 - 1.2e-13 51.1 0.0 3.2e-11 43.1 0.0 2.2 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 GAP91002.1 - 3e-08 33.9 1.0 4.3e-08 33.4 1.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 GAP91002.1 - 3.2e-08 32.9 0.0 4.3e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) NTP_transf_3 PF12804.7 GAP91002.1 - 0.024 15.0 0.2 0.063 13.6 0.1 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain Terpene_synth_C PF03936.16 GAP91004.1 - 0.038 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain DUF1080 PF06439.11 GAP91004.1 - 0.11 12.6 0.7 13 5.8 0.3 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1080) HATPase_c PF02518.26 GAP91005.1 - 5.7e-25 88.0 0.2 1.3e-24 86.8 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 GAP91005.1 - 5.8e-22 78.0 0.0 1.1e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 GAP91005.1 - 1.7e-21 76.3 1.0 3e-11 43.5 0.7 3.5 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 GAP91005.1 - 7.6e-20 70.7 0.1 2.5e-19 69.1 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 GAP91005.1 - 4.9e-09 36.4 0.0 0.014 15.7 0.0 4.2 5 0 0 5 5 5 2 PAS domain PAS_4 PF08448.10 GAP91005.1 - 3.7e-08 33.6 0.3 2.8e-07 30.8 0.2 2.7 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 GAP91005.1 - 4.3e-06 26.7 0.0 0.16 11.9 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 GAP91005.1 - 0.051 13.6 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 0 PAS domain Arylsulfotran_2 PF14269.6 GAP91006.1 - 1.4e-45 156.0 0.1 2e-45 155.5 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 GAP91006.1 - 1.4e-17 63.7 0.3 4.5e-17 62.0 0.3 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Peptidase_C62 PF12380.8 GAP91006.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase Peptidase_M13_N PF05649.13 GAP91007.1 - 1e-82 278.9 0.0 1.4e-82 278.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 GAP91007.1 - 4.7e-61 206.0 0.6 7.2e-61 205.4 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M13 Cytochrom_B561 PF03188.16 GAP91008.1 - 2.4e-17 63.3 6.7 4.7e-17 62.4 6.7 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF998 PF06197.13 GAP91008.1 - 0.03 13.9 16.1 1.3 8.6 16.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF4079 PF13301.6 GAP91008.1 - 0.23 11.6 16.4 1.2 9.3 3.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) DUF2306 PF10067.9 GAP91008.1 - 0.66 10.2 9.3 0.18 12.0 1.2 2.8 1 1 2 3 3 3 0 Predicted membrane protein (DUF2306) Allantoicase PF03561.15 GAP91009.1 - 8.6e-94 311.1 0.0 8.5e-47 158.7 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat DUF951 PF06107.11 GAP91009.1 - 0.19 11.7 0.0 22 5.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) DIL PF01843.19 GAP91010.1 - 1e-30 106.1 0.6 2.3e-30 104.9 0.6 1.7 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 GAP91010.1 - 1.3e-12 48.2 0.1 9.2e-12 45.4 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP91010.1 - 1.5e-11 44.6 0.1 1.2e-05 25.7 0.0 4.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 GAP91010.1 - 1e-09 38.4 0.4 0.002 18.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 GAP91010.1 - 5.3e-09 36.2 0.0 1.1e-05 25.6 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP91010.1 - 6.8e-05 23.0 0.0 0.41 11.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat HMD PF03201.16 GAP91010.1 - 0.075 13.3 0.4 58 4.0 0.0 3.4 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase RabGAP-TBC PF00566.18 GAP91011.1 - 1.1e-34 120.0 0.0 1.9e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Zip PF02535.22 GAP91012.1 - 0.13 11.4 3.8 0.19 10.9 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0492 PF15744.5 GAP91012.1 - 8.9 5.4 7.6 2.7 7.1 1.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein family UPF0492 zf-RING_2 PF13639.6 GAP91013.1 - 2.9e-05 24.3 1.1 2.9e-05 24.3 1.1 2.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 GAP91013.1 - 0.00012 22.0 6.7 0.013 15.5 0.2 3.2 3 0 0 3 3 3 2 RING-type zinc-finger Pellino PF04710.14 GAP91013.1 - 0.07 11.8 0.2 0.12 11.1 0.2 1.2 1 0 0 1 1 1 0 Pellino zf-C3HC4_3 PF13920.6 GAP91013.1 - 0.62 10.0 7.8 0.4 10.6 3.1 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Meth_synt_2 PF01717.18 GAP91015.1 - 1.6e-149 497.6 0.0 1.5e-144 481.3 0.0 3.1 4 0 0 4 4 4 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 GAP91015.1 - 3.8e-118 394.6 0.5 2.5e-111 372.2 0.0 2.8 4 0 0 4 4 4 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 GAP91015.1 - 0.00037 19.7 0.0 0.01 15.0 0.0 2.3 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) CBM39 PF15886.5 GAP91015.1 - 0.038 13.9 0.1 0.082 12.8 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) VbhA PF18495.1 GAP91015.1 - 0.17 11.7 0.2 3 7.8 0.1 2.6 2 0 0 2 2 2 0 Antitoxin VbhA CENP-B_dimeris PF09026.10 GAP91016.1 - 0.58 10.6 2.1 0.79 10.1 1.2 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CENP-Q PF13094.6 GAP91017.1 - 4.7e-06 26.9 1.5 3.2e-05 24.2 0.1 2.3 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit CENP-Q PF13094.6 GAP91018.1 - 3.1e-07 30.7 0.6 3.1e-07 30.7 0.6 3.3 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Cnl2_NKP2 PF09447.10 GAP91020.1 - 4.1e-27 94.1 0.4 9.8e-27 92.9 0.4 1.7 1 0 0 1 1 1 1 Cnl2/NKP2 family protein DUF2017 PF09438.10 GAP91020.1 - 0.0086 16.0 0.8 0.013 15.3 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF2017) HSA PF07529.13 GAP91020.1 - 0.039 14.3 0.2 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 HSA APG6_N PF17675.1 GAP91020.1 - 0.17 12.4 4.4 0.47 11.0 4.3 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Tudor-knot PF11717.8 GAP91021.1 - 4.1e-09 36.2 2.0 6.8e-09 35.5 2.0 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 GAP91021.1 - 0.028 14.3 0.9 0.046 13.6 0.9 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain MRG PF05712.13 GAP91022.1 - 1.5e-48 164.8 0.0 1.7e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 MRG Ribosomal_L30 PF00327.20 GAP91023.1 - 1.6e-16 59.9 0.1 2.1e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Citrate_synt PF00285.21 GAP91024.1 - 8.5e-21 74.4 0.0 2.1e-17 63.3 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 GAP91024.1 - 2.1e-19 70.0 0.0 7e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 GAP91024.1 - 1.3e-14 54.3 0.2 2.6e-14 53.3 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 GAP91024.1 - 7.3e-08 32.3 0.0 7.1e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GAP91024.1 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 CoA binding domain Citrate_bind PF16114.5 GAP91025.1 - 1.3e-86 288.6 0.1 2e-86 288.0 0.1 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 GAP91025.1 - 5.4e-08 32.6 0.0 8.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 GAP91025.1 - 0.028 12.5 0.1 0.042 12.0 0.1 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Beta-lactamase PF00144.24 GAP91026.1 - 1e-32 113.7 0.0 1.2e-32 113.5 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase TPR_12 PF13424.6 GAP91027.1 - 5.7e-37 125.9 18.8 1.5e-13 50.8 1.0 5.5 4 1 1 6 6 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAP91027.1 - 4.7e-30 102.6 15.8 1.8e-05 24.4 0.2 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_MalT PF17874.1 GAP91027.1 - 5.5e-12 45.7 18.1 9.2e-09 35.1 6.1 2.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 GAP91027.1 - 1.3e-09 37.8 11.5 0.4 11.4 0.2 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAP91027.1 - 1.2e-08 35.3 11.7 0.24 11.9 0.1 6.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAP91027.1 - 2.5e-08 33.4 9.6 0.27 11.4 0.1 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAP91027.1 - 4.5e-08 32.7 1.2 28 5.3 0.1 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 GAP91027.1 - 2.4e-07 30.3 11.4 1.9 8.8 0.1 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAP91027.1 - 2.8e-06 27.9 3.7 0.36 11.5 0.1 5.2 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 GAP91027.1 - 7.1e-06 25.6 2.2 3.5 7.6 0.1 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_22 PF13401.6 GAP91027.1 - 1.6e-05 25.2 0.0 0.00013 22.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 GAP91027.1 - 0.001 19.5 0.3 0.0069 16.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain TPR_14 PF13428.6 GAP91027.1 - 0.002 18.8 13.3 2.9 9.0 0.3 7.3 7 1 1 8 8 7 1 Tetratricopeptide repeat NACHT PF05729.12 GAP91027.1 - 0.0053 16.7 0.0 0.02 14.8 0.0 2.0 1 0 0 1 1 1 1 NACHT domain TPR_17 PF13431.6 GAP91027.1 - 0.017 15.4 1.5 7.4 7.2 0.0 4.1 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAP91027.1 - 0.03 15.0 3.4 38 5.2 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP91027.1 - 0.045 14.0 2.5 9.8 6.5 0.1 4.1 4 2 1 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 GAP91027.1 - 0.057 13.1 1.1 0.33 10.6 0.1 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain NB-ARC PF00931.22 GAP91027.1 - 0.077 12.2 0.0 0.3 10.3 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 GAP91027.1 - 0.087 12.6 0.1 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RPN7 PF10602.9 GAP91027.1 - 0.091 12.5 0.5 16 5.2 0.0 3.9 2 2 1 5 5 5 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 GAP91027.1 - 0.099 13.0 0.1 48 4.4 0.0 3.8 2 2 1 3 3 3 0 Tetratricopeptide repeat TniB PF05621.11 GAP91027.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 GAP91027.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea p450 PF00067.22 GAP91028.1 - 9.6e-58 196.0 0.0 1.3e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF676 PF05057.14 GAP91029.1 - 0.00015 21.4 0.2 0.00026 20.6 0.2 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 GAP91029.1 - 0.00085 20.0 0.0 0.0011 19.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAP91029.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 GAP91029.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Tyrosinase PF00264.20 GAP91030.1 - 3.2e-34 119.2 0.1 4.5e-34 118.7 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MlaC PF05494.12 GAP91030.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.5 2 0 0 2 2 2 0 MlaC protein AA_permease_2 PF13520.6 GAP91031.1 - 4e-47 161.0 48.0 5.1e-47 160.7 48.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP91031.1 - 5.8e-26 91.1 42.7 7.3e-26 90.8 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease zf-C2H2 PF00096.26 GAP91032.1 - 1.7e-10 40.7 13.7 1.8e-06 28.1 4.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP91032.1 - 2.6e-07 30.9 12.1 9.2e-05 23.0 3.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAP91032.1 - 3.8e-05 23.9 10.9 0.0052 17.2 3.0 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2HC_2 PF13913.6 GAP91032.1 - 0.0023 17.8 2.3 0.0023 17.8 2.3 1.7 2 0 0 2 2 1 1 zinc-finger of a C2HC-type zf-Di19 PF05605.12 GAP91032.1 - 0.009 16.3 4.1 0.016 15.5 4.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 GAP91032.1 - 0.011 16.0 1.4 0.019 15.3 0.6 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-UBR PF02207.20 GAP91032.1 - 0.012 15.7 1.5 0.023 14.9 1.5 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zinc_ribbon_9 PF14369.6 GAP91032.1 - 0.03 14.6 1.1 2.2 8.6 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_11 PF16622.5 GAP91032.1 - 0.046 13.5 12.2 0.12 12.2 3.2 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn-C2H2_12 PF18112.1 GAP91032.1 - 0.12 12.8 1.4 0.73 10.3 1.8 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2256 PF10013.9 GAP91032.1 - 0.15 12.2 0.9 0.23 11.6 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_5 PF13909.6 GAP91032.1 - 0.3 10.9 10.2 0.43 10.4 3.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 GAP91032.1 - 0.39 11.1 3.9 1.8 9.0 0.8 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 GAP91032.1 - 0.55 10.4 2.8 3 8.0 0.3 2.3 1 1 1 2 2 2 0 Zinc ribbon domain DUF4636 PF15468.6 GAP91032.1 - 0.6 9.8 4.0 0.59 9.8 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4636) ADK_lid PF05191.14 GAP91032.1 - 1.4 9.0 5.8 0.45 10.5 2.4 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid Zn_ribbon_SprT PF17283.2 GAP91032.1 - 2.6 8.0 7.4 12 5.9 0.4 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain WD40 PF00400.32 GAP91033.1 - 6.2e-23 80.7 7.6 8.6e-07 29.6 0.6 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP91033.1 - 1.1e-10 41.7 0.6 0.00039 20.6 0.0 4.7 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 GAP91033.1 - 0.00036 20.0 0.2 3.1 7.1 0.0 3.5 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 GAP91033.1 - 0.0022 17.9 0.0 0.044 13.7 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 GAP91033.1 - 0.005 16.6 1.1 2.3 7.9 0.1 3.0 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 GAP91033.1 - 0.019 13.9 0.1 4 6.3 0.0 2.8 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAP91033.1 - 0.022 13.3 0.1 0.26 9.8 0.0 1.9 1 1 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 GAP91033.1 - 0.029 13.0 0.0 1.3 7.6 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF4265 PF14085.6 GAP91033.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Septin PF00735.18 GAP91034.1 - 7.5e-113 376.5 0.6 8.9e-113 376.2 0.6 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 GAP91034.1 - 6.1e-08 32.7 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAP91034.1 - 1.2e-05 24.9 0.6 0.0041 16.7 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 GAP91034.1 - 1.9e-05 24.1 0.0 3.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 GAP91034.1 - 2.5e-05 24.2 0.2 0.00043 20.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 GAP91034.1 - 0.0011 19.0 0.2 1.4 9.0 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.6 GAP91034.1 - 0.0056 17.0 0.0 0.013 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP91034.1 - 0.0057 17.1 0.0 0.03 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 GAP91034.1 - 0.0079 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 GAP91034.1 - 0.0099 15.4 0.0 0.061 12.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 GAP91034.1 - 0.011 16.3 0.4 0.025 15.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 GAP91034.1 - 0.037 13.4 0.1 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 GAP91034.1 - 0.058 12.5 0.2 0.43 9.7 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Roc PF08477.13 GAP91034.1 - 0.07 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 GAP91034.1 - 0.086 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Microtub_bd PF16796.5 GAP91034.1 - 0.1 12.5 0.1 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding AAA_29 PF13555.6 GAP91034.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.21 GAP91035.1 - 5.5e-59 198.9 0.0 6.4e-59 198.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 GAP91035.1 - 7e-06 26.1 0.0 0.0028 17.7 0.0 2.3 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 GAP91035.1 - 0.00041 20.8 0.1 0.00085 19.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 GAP91035.1 - 0.00045 20.2 0.0 0.0028 17.6 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 GAP91035.1 - 0.00099 19.4 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAP91035.1 - 0.0011 19.2 0.1 0.019 15.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAP91035.1 - 0.0011 19.5 0.0 0.0042 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAP91035.1 - 0.002 17.9 0.1 0.18 11.5 0.0 2.1 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 GAP91035.1 - 0.035 14.0 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 GAP91035.1 - 0.053 13.0 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 GAP91035.1 - 0.094 12.7 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAP91035.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 GAP91035.1 - 0.12 12.6 0.2 1 9.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 GAP91035.1 - 0.14 11.9 0.1 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase Glyco_hydro_72 PF03198.14 GAP91036.1 - 3.7e-116 387.8 0.2 4.4e-116 387.5 0.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase zf-C2H2 PF00096.26 GAP91037.1 - 1.7e-08 34.4 9.7 0.0013 19.1 2.3 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 GAP91037.1 - 2.6e-06 27.4 12.2 7e-06 26.1 12.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP91037.1 - 1.1e-05 24.7 0.0 3.9e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 GAP91037.1 - 0.002 18.8 7.9 0.011 16.5 0.5 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP91037.1 - 0.019 15.2 3.5 4.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 GAP91037.1 - 0.025 14.9 0.7 0.054 13.8 0.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 GAP91037.1 - 0.13 12.3 5.2 4.6 7.4 1.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 GAP91037.1 - 0.21 12.0 1.2 19 5.8 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 GAP91037.1 - 0.23 11.8 4.9 3.1 8.2 1.8 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 GAP91037.1 - 4.3 7.9 16.3 0.062 13.8 2.2 3.7 3 0 0 3 3 3 0 Zinc-finger double domain NmrA PF05368.13 GAP91038.1 - 3.6e-25 88.9 0.6 6.3e-25 88.1 0.6 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP91038.1 - 3e-19 69.6 2.7 2.2e-18 66.8 0.3 2.2 1 1 1 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 GAP91038.1 - 1.6e-05 24.5 0.1 0.00017 21.1 0.1 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAP91038.1 - 0.0026 17.0 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 GAP91038.1 - 0.022 13.9 0.1 0.042 12.9 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 GAP91038.1 - 0.033 13.2 0.3 1.4 7.9 0.1 2.8 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 GAP91038.1 - 0.061 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus BRX_N PF13713.6 GAP91038.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Semialdhyde_dh PF01118.24 GAP91038.1 - 0.12 12.8 0.3 0.33 11.4 0.3 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PAF-AH_p_II PF03403.13 GAP91039.1 - 1.1e-37 129.5 0.0 4.4e-31 107.7 0.0 2.0 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 GAP91039.1 - 3.5e-05 23.2 1.9 0.0023 17.2 0.2 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 GAP91039.1 - 4.8e-05 22.4 0.0 0.01 14.8 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.11 GAP91039.1 - 0.0041 16.2 0.0 0.0085 15.1 0.0 1.4 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_6 PF12697.7 GAP91039.1 - 0.0046 17.6 0.0 0.011 16.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family EcKinase PF02958.20 GAP91040.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DNA_pol_delta_4 PF04081.13 GAP91041.1 - 7e-40 136.4 2.7 9.6e-40 136.0 2.7 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF1682 PF07946.14 GAP91041.1 - 0.0074 15.5 1.3 0.0086 15.3 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.12 GAP91041.1 - 0.22 11.3 4.4 0.31 10.8 4.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Q_salvage PF10343.9 GAP91042.1 - 2.6e-104 348.8 0.0 3.2e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family ThiF PF00899.21 GAP91043.1 - 7.4e-75 251.4 0.0 1.1e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 GAP91043.1 - 2.3e-22 79.4 0.2 2.3e-22 79.4 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 GAP91043.1 - 6.8e-09 36.0 0.8 3.9e-07 30.3 0.4 2.4 1 1 1 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 GAP91043.1 - 0.00086 19.7 0.1 0.0022 18.4 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 GAP91043.1 - 0.0069 16.5 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 GAP91043.1 - 0.16 12.2 1.0 2.5 8.4 1.0 2.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DivIC PF04977.15 GAP91043.1 - 0.56 10.0 4.5 6.5 6.6 0.1 3.0 3 0 0 3 3 3 0 Septum formation initiator adh_short PF00106.25 GAP91044.1 - 2.2e-46 157.8 0.1 4.2e-38 130.8 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP91044.1 - 2.9e-36 125.2 0.0 1.4e-26 93.5 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP91044.1 - 4e-11 43.1 0.1 5.6e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAP91044.1 - 0.036 14.0 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 GAP91044.1 - 0.082 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-Mss51 PF13824.6 GAP91045.1 - 3.1e-30 104.0 5.5 6.4e-30 103.0 5.5 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 GAP91045.1 - 0.0029 17.7 0.9 0.0029 17.7 0.9 2.2 2 0 0 2 2 2 1 MYND finger MMS1_N PF10433.9 GAP91046.1 - 3.5e-156 520.7 0.0 8.5e-156 519.4 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAP91046.1 - 9.9e-103 343.8 0.0 2.2e-100 336.1 0.0 2.6 2 0 0 2 2 2 2 CPSF A subunit region UBA_4 PF14555.6 GAP91047.1 - 0.00026 20.8 0.2 0.00057 19.7 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.20 GAP91047.1 - 0.0015 18.6 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 LysM domain VASt PF16016.5 GAP91048.1 - 2e-33 116.0 0.7 7.1e-33 114.2 0.7 2.0 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 GAP91048.1 - 3.6e-13 49.8 0.0 6.4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 GAP91048.1 - 2.7e-06 27.8 0.1 1.2e-05 25.7 0.1 2.3 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 GAP91048.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.8 2 0 0 2 2 2 0 GRAM domain DUF3074 PF11274.8 GAP91049.1 - 3.1e-55 187.0 0.0 7.7e-55 185.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.19 GAP91049.1 - 0.00056 19.4 0.0 0.016 14.6 0.0 2.3 2 0 0 2 2 2 1 START domain TFIIA PF03153.13 GAP91049.1 - 0.0025 17.9 2.9 0.0038 17.3 2.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PHM7_cyt PF14703.6 GAP91049.1 - 1.2 9.3 6.9 2.1 8.5 6.9 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Dicty_REP PF05086.12 GAP91049.1 - 2.9 5.7 7.1 4.2 5.2 7.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RR_TM4-6 PF06459.12 GAP91049.1 - 5 6.9 13.6 9.9 5.9 13.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIIAH PF12685.7 GAP91049.1 - 8.6 6.1 7.1 17 5.1 7.1 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Cas_Csy1 PF09611.10 GAP91050.1 - 0.15 11.1 1.1 0.22 10.6 1.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) AIG1 PF04548.16 GAP91051.1 - 2.6e-11 43.3 0.1 4.1e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GAP91051.1 - 1.1e-05 25.5 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP91051.1 - 0.00023 21.1 0.1 0.00049 20.0 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 GAP91051.1 - 0.00053 20.1 0.7 0.15 12.1 0.1 2.7 1 1 1 2 2 2 2 Dynamin family Septin PF00735.18 GAP91051.1 - 0.0041 16.4 0.1 0.011 15.1 0.1 1.7 1 1 0 1 1 1 1 Septin AAA_33 PF13671.6 GAP91051.1 - 0.06 13.5 0.2 0.12 12.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 GAP91051.1 - 0.088 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATG16 PF08614.11 GAP91052.1 - 0.00072 19.8 8.9 0.00072 19.8 8.9 5.2 1 1 4 5 5 5 3 Autophagy protein 16 (ATG16) Spc7 PF08317.11 GAP91052.1 - 0.0044 16.0 13.1 0.0044 16.0 13.1 5.3 1 1 4 5 5 5 3 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 GAP91052.1 - 0.021 14.8 7.8 0.021 14.8 7.8 8.8 1 1 8 9 9 9 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 GAP91052.1 - 0.027 14.9 95.3 0.74 10.2 9.1 4.2 1 1 2 4 4 4 0 Fez1 XLF PF09302.11 GAP91052.1 - 0.033 14.4 0.3 0.033 14.4 0.3 9.4 2 2 7 9 9 9 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF4200 PF13863.6 GAP91052.1 - 4.9 7.6 109.9 0.052 14.0 16.2 7.2 1 1 5 6 6 6 0 Domain of unknown function (DUF4200) Fungal_trans PF04082.18 GAP91055.1 - 5.1e-19 68.3 0.0 8.2e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAP91055.1 - 1.1e-08 35.0 13.4 0.00019 21.7 2.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP91055.1 - 2.3e-06 27.8 7.1 2.3e-06 27.8 7.1 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP91055.1 - 0.00051 20.6 13.0 0.037 14.9 2.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger C1_4 PF07975.12 GAP91055.1 - 0.39 11.0 2.1 0.9 9.8 2.1 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain K_channel_TID PF07941.11 GAP91055.1 - 0.52 10.8 13.2 3.8 8.0 13.2 2.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain zf-C2H2_jaz PF12171.8 GAP91055.1 - 0.99 9.8 3.7 0.43 10.9 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP91055.1 - 2.9 8.4 5.2 0.63 10.5 1.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ArAE_2_N PF10337.9 GAP91056.1 - 1.7e-36 126.3 13.3 1.4e-27 96.9 0.0 3.4 3 1 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 GAP91056.1 - 3.4e-18 66.0 15.2 3.4e-18 66.0 15.2 2.7 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 GAP91056.1 - 0.00017 21.5 0.0 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 CBF PF03914.17 GAP91056.1 - 0.17 11.9 0.0 0.53 10.3 0.0 1.8 1 0 0 1 1 1 0 CBF/Mak21 family ALMT PF11744.8 GAP91056.1 - 4.6 6.0 13.8 0.52 9.1 5.4 2.5 2 1 0 2 2 2 0 Aluminium activated malate transporter DUF4604 PF15377.6 GAP91057.1 - 0.11 12.9 7.4 0.14 12.6 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RNase_H PF00075.24 GAP91058.1 - 0.0039 17.4 0.0 0.31 11.2 0.0 2.0 1 1 1 2 2 2 2 RNase H TarH PF02203.15 GAP91059.1 - 0.081 12.8 0.7 0.15 12.0 0.7 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue zf-Di19 PF05605.12 GAP91060.1 - 0.065 13.5 3.8 6.5 7.1 0.1 3.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 GAP91060.1 - 2 8.2 5.6 18 5.2 0.2 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain UDPGT PF00201.18 GAP91061.1 - 2.2e-07 30.0 0.0 4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 GAP91061.1 - 0.031 14.3 0.0 0.085 12.9 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain RIP PF00161.19 GAP91062.1 - 4.5e-37 127.6 0.0 6.4e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome inactivating protein Pyr_redox_2 PF07992.14 GAP91063.1 - 2.2e-17 63.2 0.1 2.4e-17 63.1 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP91063.1 - 8.5e-10 39.1 0.0 2.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP91063.1 - 0.00083 18.5 0.1 0.41 9.7 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.6 GAP91063.1 - 0.0021 17.3 0.1 0.0052 16.0 0.1 1.5 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 GAP91063.1 - 0.0049 16.5 1.4 1.8 8.1 0.1 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAP91063.1 - 0.006 15.9 1.7 0.41 9.8 0.3 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAP91063.1 - 0.022 14.0 0.4 0.36 10.0 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 GAP91063.1 - 0.026 15.0 0.2 0.57 10.6 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 GAP91063.1 - 0.03 13.2 0.1 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 GAP91063.1 - 0.045 12.8 0.5 0.078 12.0 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 GAP91063.1 - 0.078 13.0 0.9 0.92 9.5 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ribosomal_60s PF00428.19 GAP91065.1 - 0.00067 20.2 4.6 0.001 19.6 4.6 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein DNA_pol_phi PF04931.13 GAP91065.1 - 1.4 7.0 2.3 1.6 6.8 2.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Acetyltransf_8 PF13523.6 GAP91066.1 - 5.7e-46 155.8 0.3 8.6e-46 155.2 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAP91066.1 - 0.1 13.3 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 GAP91068.1 - 3.4e-105 352.1 0.0 4.7e-105 351.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP91068.1 - 7.7e-12 46.0 2.9 4e-11 43.7 2.9 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 GAP91069.1 - 1.3e-30 106.6 52.0 5.2e-29 101.3 50.0 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily YrhC PF14143.6 GAP91069.1 - 0.39 10.8 3.6 0.61 10.2 0.3 3.2 3 1 1 4 4 4 0 YrhC-like protein ABC_membrane PF00664.23 GAP91070.1 - 1.2e-88 297.4 27.7 4.4e-50 170.9 1.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 GAP91070.1 - 7.4e-62 207.9 0.0 2.1e-29 102.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 GAP91070.1 - 1.4e-16 60.6 0.0 2.7e-06 27.0 0.0 4.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 GAP91070.1 - 5.7e-08 32.4 0.1 0.0045 16.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 GAP91070.1 - 9.9e-08 32.5 1.6 0.0073 16.7 0.3 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAP91070.1 - 1.8e-07 31.5 0.3 0.05 13.9 0.0 3.9 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 GAP91070.1 - 3.1e-06 27.2 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase APS_kinase PF01583.20 GAP91070.1 - 1e-05 25.5 0.1 0.003 17.5 0.1 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.6 GAP91070.1 - 1.4e-05 25.7 0.0 0.26 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 GAP91070.1 - 3.2e-05 23.7 1.1 0.1 12.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 GAP91070.1 - 8.6e-05 23.1 0.1 0.55 10.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 GAP91070.1 - 0.00011 22.0 0.0 0.12 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 GAP91070.1 - 0.00012 21.7 0.1 0.37 10.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 GAP91070.1 - 0.00026 21.2 2.2 0.76 10.1 0.0 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 GAP91070.1 - 0.00038 20.4 4.6 0.042 13.6 0.1 3.2 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 GAP91070.1 - 0.0021 16.9 0.4 0.017 14.0 0.0 2.5 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_33 PF13671.6 GAP91070.1 - 0.0025 18.0 0.1 1.9 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 GAP91070.1 - 0.0026 17.6 0.0 0.71 9.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 GAP91070.1 - 0.0033 17.1 0.1 5.8 6.5 0.0 3.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain DUF87 PF01935.17 GAP91070.1 - 0.0041 17.2 0.1 0.86 9.7 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_5 PF07728.14 GAP91070.1 - 0.0094 16.0 0.0 5.7 6.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 GAP91070.1 - 0.013 15.6 0.8 3 7.9 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA PF00004.29 GAP91070.1 - 0.024 15.0 0.0 16 5.9 0.0 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 GAP91070.1 - 0.029 13.6 0.1 5.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 GAP91070.1 - 0.062 13.7 0.1 17 5.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 GAP91070.1 - 0.12 11.4 0.0 7.2 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_7 PF12775.7 GAP91070.1 - 0.2 11.1 0.0 5.9 6.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ADH_N PF08240.12 GAP91071.1 - 1.9e-29 101.8 0.1 2.9e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP91071.1 - 2.6e-24 85.7 0.0 4e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP91071.1 - 2.1e-05 25.6 0.0 3.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 GAP91071.1 - 0.046 13.0 0.2 0.074 12.3 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ank_2 PF12796.7 GAP91072.1 - 5.4e-16 59.0 0.1 5.2e-11 43.0 0.1 3.9 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP91072.1 - 1.1e-14 54.5 1.3 1.8e-06 28.4 0.0 5.4 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP91072.1 - 1.9e-13 49.3 0.1 0.068 13.8 0.0 6.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 GAP91072.1 - 2.9e-13 49.7 0.3 0.0039 17.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 GAP91072.1 - 3.4e-12 46.2 0.0 0.023 15.1 0.0 5.5 5 1 0 5 5 5 3 Ankyrin repeat CorA PF01544.18 GAP91072.1 - 8.7e-06 25.3 4.0 8.7e-06 25.3 4.0 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein MSA-2c PF12238.8 GAP91074.1 - 0.041 13.9 0.3 0.068 13.2 0.3 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c ACC_central PF08326.12 GAP91075.1 - 1.1e-274 913.2 0.0 1.4e-274 912.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 GAP91075.1 - 1.4e-184 614.3 0.0 2.3e-184 613.6 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 GAP91075.1 - 1.1e-51 175.4 0.0 2.2e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 GAP91075.1 - 7.4e-28 97.3 0.7 2.9e-27 95.4 0.1 2.3 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 GAP91075.1 - 1.2e-22 80.0 0.0 1.4e-20 73.3 0.0 2.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 GAP91075.1 - 7e-18 64.2 0.5 2.4e-17 62.5 0.5 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAP91075.1 - 0.0021 17.9 0.1 0.014 15.2 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like GxGYxYP_N PF16216.5 GAP91075.1 - 0.011 16.0 0.1 0.024 14.8 0.1 1.5 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Dala_Dala_lig_C PF07478.13 GAP91075.1 - 0.024 14.2 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 GAP91075.1 - 0.04 14.0 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain NUDE_C PF04880.13 GAP91076.1 - 1.4e-39 136.4 12.2 1.4e-39 136.4 12.2 3.9 2 1 2 4 4 2 1 NUDE protein, C-terminal conserved region ERM PF00769.19 GAP91076.1 - 0.0038 17.1 25.7 0.0038 17.1 25.7 2.3 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.7 GAP91076.1 - 0.0087 16.2 35.4 0.69 10.1 1.0 4.1 2 1 2 4 4 4 2 Tropomyosin like ZapB PF06005.12 GAP91076.1 - 0.013 15.9 7.3 0.013 15.9 7.3 4.4 2 1 2 4 4 4 0 Cell division protein ZapB Filament PF00038.21 GAP91076.1 - 0.059 12.9 28.9 0.053 13.1 27.0 1.7 2 0 0 2 2 2 0 Intermediate filament protein Chibby PF14645.6 GAP91076.1 - 0.38 11.2 9.6 2.3 8.6 3.4 2.5 1 1 1 2 2 2 0 Chibby family YjbH PF06082.11 GAP91076.1 - 1.2 7.9 7.2 1.8 7.3 7.2 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH TSNAXIP1_N PF15739.5 GAP91076.1 - 1.3 9.4 15.7 0.024 15.0 4.9 2.5 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus FTCD_C PF04961.12 GAP91076.1 - 1.3 8.7 10.4 0.079 12.7 5.0 1.6 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Fez1 PF06818.15 GAP91076.1 - 2.3 8.6 27.9 0.4 11.1 11.6 3.0 2 1 1 3 3 3 0 Fez1 KLRAQ PF10205.9 GAP91076.1 - 2.6 8.3 14.9 5.1 7.4 4.8 2.9 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein AAA_13 PF13166.6 GAP91076.1 - 4 6.0 20.8 6.2 5.3 20.8 1.2 1 0 0 1 1 1 0 AAA domain Fmp27_WPPW PF10359.9 GAP91076.1 - 5.5 5.7 17.9 0.24 10.2 9.8 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain TPR_MLP1_2 PF07926.12 GAP91076.1 - 5.6 7.0 38.2 0.45 10.6 10.8 4.2 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein SOGA PF11365.8 GAP91076.1 - 6.7 7.9 21.8 0.081 14.1 2.7 3.7 2 1 1 4 4 2 0 Protein SOGA Tropomyosin PF00261.20 GAP91076.1 - 7.2 5.9 36.4 2.4 7.4 10.5 3.4 2 1 1 4 4 4 0 Tropomyosin DHR10 PF18595.1 GAP91076.1 - 7.3 6.7 37.1 0.44 10.6 15.4 3.4 2 1 0 3 3 3 0 Designed helical repeat protein 10 domain DUF3669 PF12417.8 GAP91077.1 - 9.7e-19 67.3 0.1 1.5e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 Zinc finger protein Velvet PF11754.8 GAP91078.1 - 2.8e-05 24.2 0.0 3.7e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Wzt_C PF14524.6 GAP91078.1 - 0.05 13.6 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 Wzt C-terminal domain BolA PF01722.18 GAP91079.1 - 5.3e-11 42.6 0.0 2.3e-10 40.6 0.0 2.1 2 1 0 2 2 2 1 BolA-like protein Peptidase_S8 PF00082.22 GAP91080.1 - 3.4e-41 141.4 0.0 1.1e-40 139.8 0.0 1.7 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 GAP91080.1 - 7.5e-20 71.7 0.0 1.6e-19 70.7 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 GAP91080.1 - 5.9e-09 35.8 1.1 1.4e-07 31.5 0.1 2.8 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.6 GAP91080.1 - 0.0028 17.5 0.0 0.0083 16.0 0.0 1.8 1 0 0 1 1 1 1 FlgD Ig-like domain COesterase PF00135.28 GAP91081.1 - 1.8e-61 208.6 0.1 2.4e-61 208.2 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family SnoaL PF07366.12 GAP91081.1 - 1.2e-23 83.2 0.1 8.9e-23 80.5 0.0 2.1 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 GAP91081.1 - 1.1e-08 35.6 1.5 2.3e-06 28.2 0.1 2.6 2 0 0 2 2 2 2 SnoaL-like domain Abhydrolase_3 PF07859.13 GAP91081.1 - 1.6e-05 24.9 0.5 4.8e-05 23.3 0.5 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold SSP160 PF06933.11 GAP91081.1 - 2.2 6.4 7.4 3.4 5.7 7.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAD_binding_4 PF01565.23 GAP91082.1 - 3.6e-29 101.3 0.7 5.4e-29 100.7 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP91082.1 - 9.1e-12 44.9 0.0 2.2e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like TPP_enzyme_N PF02776.18 GAP91083.1 - 9.9e-42 142.5 0.0 6.3e-40 136.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 GAP91083.1 - 3.7e-22 78.7 0.0 9.9e-22 77.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 GAP91083.1 - 4.8e-11 42.5 0.0 2.5e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain UDPGT PF00201.18 GAP91083.1 - 0.04 12.7 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Cyclin PF08613.11 GAP91084.1 - 1.8e-45 155.2 0.2 7.7e-45 153.2 0.2 1.9 1 1 0 1 1 1 1 Cyclin TFIIA PF03153.13 GAP91084.1 - 5.7 6.8 12.5 8.1 6.3 12.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M24 PF00557.24 GAP91085.1 - 1.5e-58 198.0 0.0 2.1e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 GAP91085.1 - 5.7e-23 81.0 0.0 1e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3597 PF12200.8 GAP91085.1 - 0.2 12.2 1.5 0.39 11.3 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Peptidase_S10 PF00450.22 GAP91086.1 - 5.6e-87 292.8 0.0 7.3e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CBM_21 PF03370.13 GAP91088.1 - 1.2e-33 115.6 0.3 1.9e-33 115.0 0.3 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 GAP91088.1 - 1.3e-09 38.5 0.7 2.6e-09 37.5 0.7 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Phosphoesterase PF04185.14 GAP91089.1 - 5.2e-35 121.3 2.9 1.6e-34 119.7 2.9 1.6 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.19 GAP91090.1 - 1.6e-58 198.1 0.0 2.4e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 VIT family HeLo PF14479.6 GAP91092.1 - 5.5e-07 29.6 3.5 0.0085 16.0 0.0 2.7 2 1 1 3 3 3 2 Prion-inhibition and propagation DUF2080 PF09853.9 GAP91094.1 - 0.0036 17.0 0.1 0.0078 15.9 0.0 1.5 2 0 0 2 2 2 1 Putative transposon-encoded protein (DUF2080) Ferric_reduct PF01794.19 GAP91095.1 - 1.3e-19 70.5 12.5 4e-19 69.0 11.4 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAP91095.1 - 1.6e-12 47.5 0.0 3.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 GAP91095.1 - 1.2e-11 45.0 0.0 1.9e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain tRNA-synt_1d PF00750.19 GAP91096.1 - 5.3e-101 338.0 2.6 7.1e-101 337.6 2.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 GAP91096.1 - 2.6e-28 98.6 0.1 5.8e-28 97.5 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 GAP91096.1 - 0.057 14.0 0.0 0.16 12.6 0.0 1.8 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain p450 PF00067.22 GAP91097.1 - 2.2e-21 76.2 0.0 4.4e-15 55.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 AMP-binding PF00501.28 GAP91098.1 - 4.8e-277 918.2 0.0 9e-71 238.7 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 GAP91098.1 - 4.3e-258 856.4 0.0 8.1e-86 288.5 0.0 5.2 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.25 GAP91098.1 - 1.8e-55 185.2 0.9 2.1e-13 50.4 0.1 5.2 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAP91098.1 - 8.7e-23 81.1 0.0 1.6e-07 32.2 0.0 6.0 6 0 0 6 6 6 4 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.6 GAP91098.1 - 0.00025 20.9 0.0 0.0045 16.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP91098.1 - 0.0014 19.3 0.0 0.0051 17.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP91098.1 - 0.0063 17.2 0.0 0.025 15.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP91098.1 - 0.014 15.2 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAP91098.1 - 0.051 14.2 0.0 0.24 12.1 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain FSH1 PF03959.13 GAP91100.1 - 2.4e-24 86.2 0.0 3.4e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 GAP91101.1 - 6.3e-67 225.8 0.0 1.1e-66 225.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP91101.1 - 2.6e-62 209.9 0.0 6.5e-62 208.6 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 GAP91101.1 - 6.3e-48 163.5 0.0 1.1e-47 162.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP91101.1 - 3.4e-44 151.6 0.1 1.9e-43 149.2 0.1 2.0 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP91101.1 - 6.1e-39 132.7 0.0 3.1e-38 130.4 0.0 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 GAP91101.1 - 2.1e-16 61.2 0.0 4.9e-14 53.5 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAP91101.1 - 3.6e-13 49.6 0.3 4e-12 46.3 0.1 2.9 3 1 1 4 4 4 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 GAP91101.1 - 8.6e-10 39.1 0.0 9e-07 29.3 0.0 2.7 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 GAP91101.1 - 1.2e-09 38.4 0.2 4.1e-09 36.7 0.2 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 GAP91101.1 - 1.5e-08 35.2 0.0 5.1e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAP91101.1 - 1.2e-07 31.4 0.0 2.6e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.12 GAP91101.1 - 1.5e-06 28.9 0.0 6.9e-06 26.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 GAP91101.1 - 1.8e-06 27.9 0.1 1.2e-05 25.2 0.1 2.1 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_25 PF13649.6 GAP91101.1 - 2.3e-06 28.2 0.0 2.5e-05 24.9 0.0 3.0 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP91101.1 - 3.5e-05 23.7 0.0 7.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP91101.1 - 0.00016 21.5 0.0 0.00044 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 GAP91101.1 - 0.00016 21.1 0.1 0.00053 19.4 0.1 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 GAP91101.1 - 0.0062 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 GAP91101.1 - 0.021 14.1 0.1 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lyase_aromatic PF00221.19 GAP91102.1 - 2.4e-147 491.4 0.8 3.1e-147 491.0 0.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Trp_DMAT PF11991.8 GAP91102.1 - 8.2e-90 301.8 0.0 1.3e-89 301.2 0.0 1.3 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 GAP91103.1 - 4.9e-53 180.5 0.0 6.3e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p47_phox_C PF08944.11 GAP91103.1 - 0.047 13.1 0.1 0.09 12.2 0.1 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Abhydrolase_6 PF12697.7 GAP91104.1 - 1.3e-07 32.5 20.7 3.2e-07 31.2 20.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP91104.1 - 1.3e-05 24.6 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP91104.1 - 0.00089 19.0 0.0 0.002 17.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 GAP91104.1 - 0.28 9.9 0.0 0.41 9.3 0.0 1.1 1 0 0 1 1 1 0 Ndr family p450 PF00067.22 GAP91105.1 - 1.4e-41 142.7 0.0 4.7e-27 94.8 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 PXA PF02194.15 GAP91106.1 - 1.8e-48 164.9 1.6 2.8e-48 164.3 1.6 1.3 1 0 0 1 1 1 1 PXA domain SPX PF03105.19 GAP91106.1 - 2.1 8.2 10.0 12 5.7 2.4 2.8 2 1 0 2 2 2 0 SPX domain HTH_Tnp_Tc5 PF03221.16 GAP91107.1 - 4.4e-10 39.4 0.0 1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 GAP91107.1 - 8e-07 28.6 0.1 1.3e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 GAP91107.1 - 0.0032 17.2 0.0 0.0088 15.8 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 GAP91107.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.22 GAP91107.1 - 0.04 13.8 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 GAP91107.1 - 0.076 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Phage_int_SAM_5 PF13102.6 GAP91107.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain MMR_HSR1_Xtn PF16897.5 GAP91108.1 - 4.1e-40 136.1 1.5 5.7e-39 132.4 0.5 2.4 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 GAP91108.1 - 1.1e-22 79.9 0.1 2.1e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 GAP91108.1 - 7.8e-21 74.3 0.0 3.6e-20 72.1 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAP91108.1 - 2.7e-09 36.7 0.1 1.4e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAP91108.1 - 0.00039 20.5 0.1 0.089 12.8 0.0 2.4 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 GAP91108.1 - 0.0023 17.5 0.2 9.8 5.7 0.0 3.8 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 GAP91108.1 - 0.007 15.4 0.5 0.021 13.8 0.1 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 GAP91108.1 - 0.018 14.5 0.1 3 7.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 GAP91108.1 - 0.034 14.0 0.4 3.6 7.5 0.1 2.7 2 1 0 2 2 2 0 RsgA GTPase CBS PF00571.28 GAP91108.1 - 0.065 13.7 0.0 0.2 12.2 0.0 1.8 1 0 0 1 1 1 0 CBS domain AIG1 PF04548.16 GAP91108.1 - 0.068 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.6 GAP91108.1 - 0.091 13.0 0.0 1.7 8.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.6 GAP91108.1 - 0.11 12.9 0.0 0.58 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain Steroid_dh PF02544.16 GAP91109.1 - 1.2e-14 54.6 3.8 1.2e-14 54.6 3.8 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 GAP91109.1 - 0.065 12.7 3.2 0.25 10.8 3.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ank_2 PF12796.7 GAP91110.1 - 3e-26 91.8 1.8 1.6e-12 47.9 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP91110.1 - 7.5e-15 55.1 0.1 1.8e-08 34.8 0.0 3.8 3 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 GAP91110.1 - 1.1e-12 47.7 1.5 5.4e-05 23.4 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 GAP91110.1 - 1.2e-12 46.8 1.0 0.0024 18.2 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 GAP91110.1 - 1.8e-12 47.2 1.8 1.5e-05 25.1 0.1 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) SKG6 PF08693.10 GAP91111.1 - 2e-07 30.3 1.0 3.7e-07 29.4 1.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CFEM PF05730.11 GAP91111.1 - 0.039 14.0 0.3 0.061 13.4 0.3 1.3 1 0 0 1 1 1 0 CFEM domain DUF4448 PF14610.6 GAP91111.1 - 0.11 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1180 PF06679.12 GAP91111.1 - 1.3 9.4 4.0 3.5 8.0 4.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) AAA_17 PF13207.6 GAP91113.1 - 1.1e-08 35.6 0.0 0.00031 21.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain ADK PF00406.22 GAP91113.1 - 9.9e-08 32.2 0.0 5e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_18 PF13238.6 GAP91113.1 - 3.8e-05 24.2 0.1 0.00061 20.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 GAP91113.1 - 3.8e-05 23.9 0.8 0.00018 21.7 0.2 2.2 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 GAP91113.1 - 0.0022 17.8 0.0 0.0043 16.8 0.0 1.7 1 1 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 GAP91113.1 - 0.0023 18.2 0.0 0.12 12.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain SKI PF01202.22 GAP91113.1 - 0.11 12.6 0.2 12 6.0 0.1 2.2 2 0 0 2 2 2 0 Shikimate kinase MDM10 PF12519.8 GAP91115.1 - 0.046 12.6 0.6 0.049 12.5 0.6 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FXR_C1 PF16096.5 GAP91115.1 - 0.064 13.5 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Activator_LAG-3 PF11498.8 GAP91115.1 - 0.086 11.8 18.0 0.098 11.6 18.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Prp31_C PF09785.9 GAP91115.1 - 1.1 10.2 9.1 1.9 9.4 9.1 1.4 1 1 0 1 1 1 0 Prp31 C terminal domain Presenilin PF01080.17 GAP91115.1 - 3.5 6.3 6.6 4.1 6.1 6.6 1.0 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 GAP91115.1 - 3.9 7.0 15.0 4.9 6.7 15.0 1.1 1 0 0 1 1 1 0 Spt20 family Se-cys_synth_N PF12390.8 GAP91116.1 - 0.16 12.2 5.1 8.8 6.7 0.1 3.6 3 0 0 3 3 3 0 Selenocysteine synthase N terminal ATG22 PF11700.8 GAP91117.1 - 6.3e-60 203.2 2.5 7.3e-60 202.9 2.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like WSC PF01822.19 GAP91118.1 - 5.3e-33 113.1 26.9 1.1e-17 64.0 8.7 5.2 6 0 0 6 6 6 2 WSC domain NFRKB_winged PF14465.6 GAP91118.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 NFRKB Winged Helix-like Mucin PF01456.17 GAP91118.1 - 0.84 9.6 59.7 0.84 9.6 29.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein CFEM PF05730.11 GAP91119.1 - 3.5e-07 30.2 6.1 5.6e-07 29.6 6.1 1.3 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 GAP91119.1 - 0.14 11.6 0.8 0.24 10.8 0.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain p450 PF00067.22 GAP91120.1 - 3.2e-56 191.0 0.0 4.1e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Prismane PF03063.20 GAP91121.1 - 0.057 12.1 0.8 0.081 11.6 0.8 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family UbiA PF01040.18 GAP91122.1 - 1.1e-22 80.6 15.3 1.6e-22 80.1 15.0 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family EthD PF07110.11 GAP91123.1 - 3.1e-22 79.5 2.0 3.6e-22 79.3 2.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 GAP91123.1 - 5.9e-06 26.7 0.1 3e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase LolB PF03550.14 GAP91123.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 Outer membrane lipoprotein LolB PCI PF01399.27 GAP91124.1 - 6.6e-08 33.0 0.6 1.8e-06 28.4 0.0 2.8 2 0 0 2 2 2 1 PCI domain G-gamma PF00631.22 GAP91125.1 - 7.6e-25 86.7 0.0 1.1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 GGL domain Ribosomal_L11 PF00298.19 GAP91125.1 - 0.095 13.2 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain Rdx PF10262.9 GAP91126.1 - 1.7e-32 111.5 0.0 2.5e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Rdx family Metallophos PF00149.28 GAP91127.1 - 6.2e-40 137.9 0.1 8.1e-40 137.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 GAP91127.1 - 2.7e-22 78.9 1.9 3.9e-22 78.4 1.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain zf-HC5HC2H_2 PF13832.6 GAP91128.1 - 7.1e-32 109.8 7.6 7.1e-32 109.8 7.6 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 GAP91128.1 - 1.6e-28 100.1 0.1 4e-28 98.8 0.1 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 GAP91128.1 - 1.8e-24 85.8 7.0 1.8e-24 85.8 7.0 2.7 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 GAP91128.1 - 3.4e-14 52.1 1.9 3.4e-14 52.1 1.9 2.0 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 GAP91128.1 - 8e-09 35.3 25.0 1.3e-08 34.6 9.5 2.7 2 0 0 2 2 2 2 PHD-finger DUF3918 PF13056.6 GAP91128.1 - 0.058 13.0 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) LRR_8 PF13855.6 GAP91129.1 - 9.4e-14 50.9 2.5 7.9e-07 28.8 3.3 3.7 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 GAP91129.1 - 1.3e-12 47.6 3.8 0.0027 18.1 0.4 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 GAP91129.1 - 0.0026 17.3 0.4 0.0068 15.9 0.3 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 GAP91129.1 - 0.015 15.7 6.6 45 5.2 0.3 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 GAP91129.1 - 0.18 11.9 11.4 12 6.2 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich repeat Mac PF12464.8 GAP91131.1 - 9.7e-16 57.8 0.0 1.4e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 GAP91131.1 - 4.9e-12 45.1 14.0 2.8e-11 42.7 4.6 3.6 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAP91131.1 - 4.9e-11 42.2 11.8 6.5e-11 41.8 3.6 3.1 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Subtilosin_A PF11420.8 GAP91131.1 - 0.16 11.9 1.7 0.24 11.4 0.1 2.1 2 0 0 2 2 2 0 Bacteriocin subtilosin A Biotin_lipoyl PF00364.22 GAP91133.1 - 3.2e-20 71.7 2.0 3.3e-20 71.7 0.6 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 GAP91133.1 - 1.9e-11 44.1 0.1 5.3e-11 42.7 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 GAP91133.1 - 0.0002 21.1 0.0 0.00086 19.1 0.0 2.0 2 0 0 2 2 2 1 Biotin-lipoyl like CoA_transf_3 PF02515.17 GAP91136.1 - 6.3e-35 121.0 0.0 3.1e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 CoA-transferase family III Fungal_trans PF04082.18 GAP91137.1 - 2.1e-23 82.7 0.4 3.7e-23 81.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP91137.1 - 5.2e-08 32.9 12.3 1e-07 31.9 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP91138.1 - 1.4e-10 40.6 0.0 3.1e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain GST_N_3 PF13417.6 GAP91139.1 - 1.6e-14 54.0 0.0 2.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAP91139.1 - 2.1e-11 44.0 0.1 1.1e-10 41.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAP91139.1 - 5.7e-11 42.6 0.2 1.9e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP91139.1 - 1.9e-08 34.4 0.0 3.2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAP91139.1 - 3.3e-07 30.4 0.0 5.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP91139.1 - 5.7e-05 23.1 0.2 0.00015 21.7 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 GAP91139.1 - 0.015 15.6 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Glyco_hydro_16 PF00722.21 GAP91141.1 - 6.8e-11 42.0 4.5 1e-10 41.3 4.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WW PF00397.26 GAP91142.1 - 3.4e-07 30.2 2.2 9e-07 28.9 2.2 1.7 1 0 0 1 1 1 1 WW domain WRW PF10206.9 GAP91142.1 - 0.01 16.2 0.9 0.033 14.6 0.9 1.8 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f RIX1 PF08167.12 GAP91143.1 - 3.6e-56 189.9 0.3 3.6e-56 189.9 0.3 1.6 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis TPR_2 PF07719.17 GAP91144.1 - 1.2e-12 46.9 2.1 0.12 12.6 0.1 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAP91144.1 - 4.7e-11 42.5 12.8 0.033 15.0 0.1 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAP91144.1 - 2.4e-07 31.2 1.1 0.037 14.5 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAP91144.1 - 4.7e-07 29.5 7.7 0.11 12.8 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAP91144.1 - 5.5e-06 26.4 1.4 0.035 14.5 0.1 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP91144.1 - 1e-05 25.1 2.5 1.2 9.1 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAP91144.1 - 3.6e-05 24.3 2.6 36 5.1 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAP91144.1 - 0.00067 19.9 7.4 35 4.8 0.1 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAP91144.1 - 0.0036 17.2 5.1 2.4 8.4 0.1 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAP91144.1 - 0.69 10.7 7.0 0.54 11.0 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_PK PF05891.12 GAP91146.1 - 4.3e-77 258.5 0.0 5e-77 258.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 GAP91146.1 - 0.045 14.4 0.0 0.094 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SGL PF08450.12 GAP91147.1 - 1.4e-44 152.5 0.0 1.5e-43 149.2 0.0 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region CAP_N PF01213.19 GAP91147.1 - 0.33 10.4 1.3 0.5 9.8 1.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GAP91147.1 - 2.4 8.2 4.6 5.3 7.1 4.6 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 bZIP_2 PF07716.15 GAP91148.1 - 0.0018 18.3 12.5 0.0035 17.4 12.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 GAP91148.1 - 0.83 9.8 13.1 1.8 8.7 13.0 1.6 1 1 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 GAP91148.1 - 9.7 6.0 6.1 1.7 8.4 1.7 1.9 1 1 1 2 2 2 0 Septum formation initiator Sugar_tr PF00083.24 GAP91149.1 - 7e-101 338.3 24.2 8.5e-101 338.0 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP91149.1 - 3.7e-25 88.6 30.8 2.2e-19 69.6 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAP91149.1 - 0.011 14.2 3.3 0.019 13.4 3.3 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Pectate_lyase_3 PF12708.7 GAP91150.1 - 1.8e-40 139.1 10.7 1.6e-33 116.4 4.9 2.4 2 0 0 2 2 2 2 Pectate lyase superfamily protein ERG4_ERG24 PF01222.17 GAP91151.1 - 3.8e-155 516.9 9.0 4.2e-155 516.7 9.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 GAP91151.1 - 2.1e-05 24.2 0.5 0.00021 20.9 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) ADH_N PF08240.12 GAP91152.1 - 1.5e-08 34.5 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP91152.1 - 6.6e-08 32.6 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP91152.1 - 0.018 16.1 0.0 0.044 14.8 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AAA_11 PF13086.6 GAP91153.1 - 4.2 7.1 10.1 7.2 6.3 10.1 1.3 1 0 0 1 1 1 0 AAA domain DUF2040 PF09745.9 GAP91154.1 - 6.2e-36 123.1 13.1 6.2e-36 123.1 13.1 3.3 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) RIG-I_C PF18119.1 GAP91154.1 - 0.029 14.4 0.2 0.029 14.4 0.2 2.1 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain Apt1 PF10351.9 GAP91155.1 - 0.35 9.7 6.1 0.39 9.5 6.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 GAP91155.1 - 6.2 5.5 9.1 8.1 5.1 9.1 1.2 1 0 0 1 1 1 0 Presenilin Neurochondrin PF05536.11 GAP91157.1 - 1.3e-42 146.0 0.0 1.9e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Neurochondrin Voltage_CLC PF00654.20 GAP91158.1 - 8.8e-86 288.3 30.3 1.6e-85 287.4 30.3 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel zf-C3HC4_3 PF13920.6 GAP91159.1 - 1.4e-10 40.8 7.6 2.3e-10 40.2 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAP91159.1 - 1.7e-07 31.0 9.1 3.3e-07 30.1 9.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 GAP91159.1 - 8.6e-07 28.7 12.3 1.8e-06 27.7 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP91159.1 - 1.4e-06 28.5 11.2 2.9e-06 27.5 11.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 GAP91159.1 - 4.9e-06 26.4 10.1 1.1e-05 25.3 10.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAP91159.1 - 4.9e-06 26.3 11.1 8.2e-06 25.6 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP91159.1 - 9e-06 25.6 5.0 9e-06 25.6 5.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger TerY_C PF15616.6 GAP91159.1 - 0.0017 18.5 2.2 0.0025 17.9 1.4 1.6 2 0 0 2 2 2 1 TerY-C metal binding domain zf-ANAPC11 PF12861.7 GAP91159.1 - 0.0021 18.1 4.2 0.0021 18.1 4.2 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 GAP91159.1 - 0.0069 16.2 5.0 0.013 15.3 5.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 GAP91159.1 - 0.04 14.1 8.8 0.076 13.2 8.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PolC_DP2 PF03833.13 GAP91159.1 - 0.045 11.6 0.5 0.061 11.2 0.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_6 PF14835.6 GAP91159.1 - 0.11 12.4 2.8 0.21 11.5 2.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 GAP91159.1 - 1.5 8.9 4.7 3.6 7.7 4.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon Pkinase_Tyr PF07714.17 GAP91160.1 - 3.1e-05 23.4 0.0 0.48 9.7 0.0 3.6 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 GAP91160.1 - 9.7e-05 21.9 0.0 0.03 13.7 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Helo_like_N PF17111.5 GAP91161.1 - 1.2e-05 24.8 1.0 2.3e-05 23.9 1.0 1.5 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 GAP91161.1 - 0.0003 21.0 0.1 0.0012 19.0 0.1 2.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Laminin_II PF06009.12 GAP91161.1 - 0.22 11.6 3.5 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Laminin Domain II AMP-binding PF00501.28 GAP91162.1 - 5.3e-73 246.0 0.0 7.4e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 GAP91162.1 - 1.3e-28 99.9 2.7 1.6e-14 53.5 0.1 3.8 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 GAP91162.1 - 2.9e-09 37.1 0.6 0.0003 21.1 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 GAP91162.1 - 4.7e-05 24.3 0.0 0.00014 22.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 GAP91162.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Methyltransf_11 PF08241.12 GAP91163.1 - 1.3e-08 35.4 0.0 2.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP91163.1 - 7e-07 29.9 0.0 1.5e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP91163.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ank_2 PF12796.7 GAP91164.1 - 1.7e-97 320.1 18.5 5.9e-13 49.2 0.1 12.6 7 2 6 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP91164.1 - 2.2e-71 235.3 18.5 1.7e-05 25.2 0.0 16.7 13 2 2 16 16 16 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP91164.1 - 2.9e-55 183.6 22.6 2.5e-05 24.4 0.0 16.9 12 5 4 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP91164.1 - 2.3e-53 171.9 21.4 0.00016 21.8 0.1 23.4 24 0 0 24 24 24 8 Ankyrin repeat Ank PF00023.30 GAP91164.1 - 3.2e-46 153.8 33.8 5.7e-06 26.5 0.5 22.3 24 0 0 24 24 24 9 Ankyrin repeat ZZ PF00569.17 GAP91164.1 - 7e-12 45.0 6.2 1.2e-10 41.1 7.5 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type AAA_16 PF13191.6 GAP91164.1 - 0.00012 22.5 0.1 0.00059 20.3 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.13 GAP91164.1 - 0.0076 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 GAP91164.1 - 0.076 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ank_2 PF12796.7 GAP91165.1 - 4e-33 113.9 4.0 9.2e-10 39.0 0.1 8.5 4 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP91165.1 - 2.2e-29 101.4 5.2 6.9e-07 29.7 0.2 9.5 8 2 2 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP91165.1 - 2.4e-22 76.6 10.7 0.037 14.6 0.0 12.6 14 0 0 14 14 14 5 Ankyrin repeat Ank_5 PF13857.6 GAP91165.1 - 6.5e-17 61.4 8.4 0.0078 16.5 0.0 8.9 6 2 4 10 10 10 4 Ankyrin repeats (many copies) Clr5 PF14420.6 GAP91165.1 - 2.5e-09 37.2 2.3 1.3e-08 34.9 2.3 2.4 1 0 0 1 1 1 1 Clr5 domain Ank PF00023.30 GAP91165.1 - 1.3e-07 31.7 13.0 0.51 10.9 0.1 8.9 10 0 0 10 10 10 2 Ankyrin repeat FMN_dh PF01070.18 GAP91167.1 - 6.8e-110 367.4 0.0 7.8e-110 367.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 GAP91167.1 - 8.6e-05 22.1 0.2 0.00013 21.5 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 GAP91167.1 - 0.0021 17.2 0.2 0.0031 16.7 0.2 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 GAP91167.1 - 0.0026 16.8 0.3 0.0026 16.8 0.3 1.6 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 GAP91167.1 - 0.0035 16.7 0.6 2 7.6 0.0 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG SH3_12 PF18129.1 GAP91167.1 - 0.014 15.5 0.2 0.03 14.4 0.2 1.5 1 0 0 1 1 1 0 Xrn1 SH3-like domain His_biosynth PF00977.21 GAP91167.1 - 0.031 13.7 0.2 0.84 9.0 0.1 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein DAG_kinase_N PF14513.6 GAP91169.1 - 0.001 19.3 2.9 0.0012 19.0 2.9 1.0 1 0 0 1 1 1 1 Diacylglycerol kinase N-terminus Glypican PF01153.19 GAP91169.1 - 0.19 10.5 3.2 0.21 10.4 3.2 1.0 1 0 0 1 1 1 0 Glypican ABC1 PF03109.16 GAP91170.1 - 1.5e-33 115.5 0.0 2.4e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pex19 PF04614.12 GAP91172.1 - 2.3e-70 237.2 15.4 2.3e-70 237.2 15.4 1.7 2 0 0 2 2 2 1 Pex19 protein family GlutR_dimer PF00745.20 GAP91172.1 - 0.02 15.3 0.4 0.068 13.6 0.3 2.0 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Menin PF05053.13 GAP91172.1 - 0.6 8.4 4.6 0.81 8.0 4.6 1.1 1 0 0 1 1 1 0 Menin UQ_con PF00179.26 GAP91173.1 - 1.8e-47 160.5 0.0 2e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAP91173.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAP91173.1 - 0.1 12.9 0.6 0.22 11.8 0.6 1.7 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.21 GAP91174.1 - 5.9e-95 318.9 0.0 1.6e-91 307.6 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 GAP91174.1 - 3.3e-36 123.9 0.0 5.5e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAP91174.1 - 5.3e-29 101.1 0.0 1.2e-27 96.7 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAP91174.1 - 0.00024 20.7 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 GAP91174.1 - 0.0014 17.8 0.1 0.0029 16.7 0.1 1.6 1 1 0 1 1 1 1 NAD synthase QueC PF06508.13 GAP91174.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC GPI-anchored PF10342.9 GAP91175.1 - 5.7e-14 52.6 0.0 1.6e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-C2H2 PF00096.26 GAP91176.1 - 0.00043 20.6 16.4 0.059 13.8 1.5 4.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP91176.1 - 0.048 14.5 19.7 0.17 12.8 1.5 5.1 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP91176.1 - 0.14 12.5 1.9 19 5.7 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Sina PF03145.16 GAP91176.1 - 0.19 11.6 3.3 0.35 10.8 3.3 1.4 1 0 0 1 1 1 0 Seven in absentia protein family Glyco_hydro_43 PF04616.14 GAP91177.1 - 1.7e-21 76.8 3.8 3e-21 76.0 3.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Phage_Orf51 PF06194.11 GAP91177.1 - 0.044 13.8 0.2 1.7 8.7 0.0 2.6 1 1 1 2 2 2 0 Phage Conserved Open Reading Frame 51 Glyco_hydro_31 PF01055.26 GAP91178.1 - 5.7e-148 493.8 0.6 7.1e-148 493.4 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 GAP91178.1 - 7.5e-35 119.6 0.0 1.7e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 GAP91178.1 - 2.6e-14 53.3 0.5 1e-13 51.4 0.5 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like RabGAP-TBC PF00566.18 GAP91179.1 - 1.6e-49 168.5 0.0 2.3e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CENP-B_dimeris PF09026.10 GAP91179.1 - 0.46 10.9 4.4 0.88 10.0 4.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRM_1 PF00076.22 GAP91180.1 - 2.3e-35 120.2 0.4 7.3e-17 61.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAP91180.1 - 8.3e-12 45.1 0.1 8.2e-05 22.7 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 GAP91180.1 - 4.3e-05 23.4 0.1 0.23 11.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAP91180.1 - 0.051 13.6 0.1 9.1 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif PhyH PF05721.13 GAP91181.1 - 1.6e-59 201.7 0.0 2e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 GAP91181.1 - 0.0028 18.0 0.0 0.0056 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase CTP_transf_like PF01467.26 GAP91182.1 - 2.6e-23 82.8 0.0 1.2e-21 77.4 0.0 2.6 2 1 0 2 2 2 2 Cytidylyltransferase-like cNMP_binding PF00027.29 GAP91183.1 - 2.5e-40 136.5 0.0 7.5e-20 70.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF3783 PF12646.7 GAP91183.1 - 0.07 13.1 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) BCAS2 PF05700.11 GAP91184.1 - 2.5e-54 184.1 1.1 3.2e-54 183.8 1.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) OpuAC PF04069.12 GAP91184.1 - 0.059 12.9 0.1 0.077 12.6 0.1 1.2 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Ceramidase_alk PF04734.13 GAP91185.1 - 1.2e-225 749.9 0.0 1.4e-225 749.7 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 GAP91185.1 - 3e-53 180.2 0.7 1.4e-52 177.9 0.7 2.1 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal DUF3357 PF11837.8 GAP91185.1 - 0.14 12.6 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF5127 PF17168.4 GAP91186.1 - 4.7e-81 271.9 2.1 7.5e-81 271.2 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 GAP91186.1 - 1.2e-72 243.1 0.1 3.3e-72 241.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 GAP91186.1 - 1.6e-65 220.6 0.2 5.1e-65 219.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 GAP91186.1 - 2.4e-06 27.0 2.6 6.9e-06 25.5 1.8 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4964) PT PF04886.12 GAP91188.1 - 1e-10 41.0 45.8 4.2e-05 23.0 9.5 6.4 3 3 0 3 3 3 2 PT repeat ATP-synt_C PF00137.21 GAP91189.1 - 1.7e-34 117.9 35.7 9.7e-22 77.1 16.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L7Ae PF01248.26 GAP91190.1 - 3.2e-25 87.7 0.1 3.7e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 GAP91190.1 - 0.0028 17.7 0.0 0.0037 17.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 GAP91190.1 - 0.0075 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain DUF5082 PF16888.5 GAP91190.1 - 0.1 12.9 1.2 0.16 12.3 0.3 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Syja_N PF02383.18 GAP91191.1 - 2.6e-90 303.0 0.0 3.6e-90 302.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 GAP91191.1 - 1.9e-40 137.2 0.0 3.2e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Methyltransf_34 PF11312.8 GAP91192.1 - 2.5e-90 302.8 0.0 1.4e-89 300.4 0.0 2.0 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase Transketolase_N PF00456.21 GAP91193.1 - 4.2e-156 519.0 0.2 6.1e-156 518.5 0.2 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 GAP91193.1 - 1.9e-44 151.5 0.0 3.4e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 GAP91193.1 - 1e-10 41.5 0.0 1.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 GAP91193.1 - 1.6e-05 24.3 0.1 4e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 GAP91193.1 - 0.026 13.8 0.1 0.054 12.8 0.1 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DUF5308 PF17233.2 GAP91194.1 - 7.5e-46 156.4 16.0 2.5e-44 151.4 16.0 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF5308) DUF3246 PF11596.8 GAP91194.1 - 7.4 5.9 15.0 0.049 13.1 4.7 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3246) FUSC_2 PF13515.6 GAP91196.1 - 2.1e-29 102.2 6.0 2.1e-29 102.2 6.0 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 GAP91196.1 - 0.00012 20.8 15.4 0.0099 14.5 11.6 3.1 2 1 0 2 2 2 2 Fusaric acid resistance protein family ALMT PF11744.8 GAP91196.1 - 0.00016 20.7 16.7 0.0049 15.8 5.7 4.1 4 0 0 4 4 4 3 Aluminium activated malate transporter ArAE_2 PF10334.9 GAP91196.1 - 0.00025 21.0 0.1 0.00063 19.6 0.0 1.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 COPIIcoated_ERV PF07970.12 GAP91197.1 - 4.2e-35 121.6 0.0 6e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 GAP91197.1 - 5.6e-25 87.5 0.0 9e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3632 PF12311.8 GAP91198.1 - 2.2e-19 70.6 0.1 2.6e-19 70.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) N_BRCA1_IG PF16158.5 GAP91199.1 - 6.4e-35 119.9 0.5 3.7e-34 117.5 0.0 2.6 3 0 0 3 3 3 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 GAP91199.1 - 8e-20 70.4 58.1 2.3e-06 27.3 11.2 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type TAF8_C PF10406.9 GAP91199.1 - 0.1 13.2 0.1 0.42 11.2 0.1 2.1 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term C1_2 PF03107.16 GAP91199.1 - 0.48 10.8 45.8 0.15 12.4 7.8 4.6 4 0 0 4 4 4 0 C1 domain Btz PF09405.10 GAP91200.1 - 3.7e-26 91.9 0.2 1e-25 90.5 0.2 1.7 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding TFIIF_alpha PF05793.12 GAP91200.1 - 6 5.3 6.5 8.4 4.9 6.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Asp PF00026.23 GAP91201.1 - 8.5e-63 212.7 1.2 1e-62 212.4 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP91201.1 - 9.9e-14 52.0 2.6 4.7e-08 33.5 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAP91201.1 - 0.1 13.3 0.9 5.2 7.8 0.0 3.1 2 1 0 2 2 2 0 Aspartyl protease Aminotran_4 PF01063.19 GAP91202.1 - 9.7e-15 55.0 0.0 2.8e-14 53.5 0.0 1.7 1 1 0 1 1 1 1 Amino-transferase class IV TPR_1 PF00515.28 GAP91203.1 - 2.6e-41 137.8 21.5 0.00015 21.5 0.1 11.6 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 GAP91203.1 - 5.8e-37 122.8 22.3 0.00029 20.7 0.0 11.6 11 1 1 12 12 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 GAP91203.1 - 1.1e-24 86.8 2.1 0.0001 22.9 0.0 7.1 5 2 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAP91203.1 - 2e-23 80.6 18.2 0.0082 16.3 0.0 10.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 GAP91203.1 - 8.3e-21 73.4 29.8 0.00014 21.4 0.0 8.9 6 2 3 9 9 8 7 TPR repeat TPR_17 PF13431.6 GAP91203.1 - 1.4e-18 65.8 9.6 3.9e-05 23.7 0.0 9.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAP91203.1 - 3.4e-13 49.7 31.3 0.00075 19.7 0.3 9.0 4 2 5 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 GAP91203.1 - 1.6e-11 43.4 17.6 0.017 15.1 0.0 9.0 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAP91203.1 - 8.4e-11 41.9 10.8 4.6e-05 23.5 0.1 6.0 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 GAP91203.1 - 1.3e-09 38.4 23.7 3.3e-05 24.3 0.9 6.5 5 1 2 8 8 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAP91203.1 - 5.9e-09 36.0 19.0 0.015 16.0 0.5 7.9 5 3 5 10 10 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP91203.1 - 3.5e-08 33.6 13.6 0.0097 16.1 0.5 5.3 2 1 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 GAP91203.1 - 1.4e-07 31.3 4.1 2.2e-07 30.6 0.3 2.3 1 1 1 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 GAP91203.1 - 2.3e-06 27.3 22.4 0.057 13.3 0.5 7.8 10 0 0 10 10 7 2 Tetratricopeptide repeat MAS20 PF02064.15 GAP91203.1 - 0.0011 19.1 7.3 2.1 8.4 0.2 4.4 5 1 0 5 5 4 1 MAS20 protein import receptor Sel1 PF08238.12 GAP91203.1 - 0.0021 18.7 1.0 2 9.2 0.1 3.8 2 0 0 2 2 2 1 Sel1 repeat HrpB1_HrpK PF09613.10 GAP91203.1 - 0.003 17.2 0.3 0.071 12.7 0.3 2.5 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) SHNi-TPR PF10516.9 GAP91203.1 - 0.0041 16.5 13.2 0.51 9.8 0.0 5.6 6 0 0 6 6 5 1 SHNi-TPR TPR_6 PF13174.6 GAP91203.1 - 0.0054 17.3 21.1 5.4 7.9 0.0 8.0 9 0 0 9 9 6 1 Tetratricopeptide repeat MIT PF04212.18 GAP91203.1 - 0.036 14.1 14.1 8.7 6.5 0.0 6.4 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Wzy_C_2 PF11846.8 GAP91203.1 - 0.074 13.0 2.9 21 4.9 0.0 4.4 4 1 1 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal TPR_4 PF07721.14 GAP91203.1 - 0.08 13.6 0.7 29 5.7 0.0 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat DUF3808 PF10300.9 GAP91203.1 - 0.12 11.1 6.0 0.8 8.4 0.6 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3808) SPO22 PF08631.10 GAP91203.1 - 0.32 10.5 4.9 5.1 6.5 0.0 3.6 4 1 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like PknG_TPR PF16918.5 GAP91203.1 - 0.36 9.5 6.0 0.18 10.5 0.1 3.1 4 0 0 4 4 4 0 Protein kinase G tetratricopeptide repeat ANAPC5 PF12862.7 GAP91203.1 - 0.65 10.1 10.4 14 5.8 0.1 4.6 3 2 1 4 4 3 0 Anaphase-promoting complex subunit 5 TPR_3 PF07720.12 GAP91203.1 - 0.83 9.7 20.6 2 8.5 0.2 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAP91203.1 - 1 9.7 10.0 1.4 9.3 0.1 4.9 5 1 1 6 6 5 0 Tetratricopeptide repeat DUF4810 PF16068.5 GAP91203.1 - 2.8 8.6 8.0 5 7.7 0.0 4.1 4 1 0 4 4 3 0 Domain of unknown function (DUF4810) Amidohydro_1 PF01979.20 GAP91204.1 - 7.2e-18 65.0 0.1 8.3e-17 61.5 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAP91204.1 - 2.4e-09 37.2 4.3 1.1e-08 35.0 0.4 2.2 2 0 0 2 2 2 2 Amidohydrolase family AhpC-TSA_2 PF13911.6 GAP91205.1 - 1.4e-15 57.3 0.0 2.8e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 GAP91205.1 - 0.00053 19.9 0.0 0.00095 19.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Syntaxin PF00804.25 GAP91206.1 - 3.9e-23 82.2 7.5 5e-23 81.8 7.5 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 GAP91206.1 - 2.7e-11 43.3 0.4 7.9e-11 41.8 0.4 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 GAP91206.1 - 0.0015 18.9 3.0 0.0015 18.9 3.0 2.3 2 1 0 2 2 2 1 Syntaxin-like protein Allexi_40kDa PF05549.11 GAP91206.1 - 0.012 15.1 2.4 0.053 13.0 0.2 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein PBP1_TM PF14812.6 GAP91206.1 - 0.021 15.2 0.0 0.021 15.2 0.0 2.0 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sfi1_C PF10638.9 GAP91206.1 - 0.068 13.9 0.1 0.27 12.0 0.0 2.0 2 0 0 2 2 2 0 Spindle body associated protein C-terminus DUF3153 PF11353.8 GAP91206.1 - 0.074 12.6 3.2 0.071 12.7 1.2 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3153) Tup_N PF08581.10 GAP91206.1 - 0.3 11.4 3.8 5.3 7.4 0.1 3.3 3 0 0 3 3 3 0 Tup N-terminal APH PF01636.23 GAP91207.1 - 3e-18 66.6 0.0 4.4e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 GAP91207.1 - 0.00066 19.1 0.0 0.0035 16.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Brix PF04427.18 GAP91208.1 - 4.5e-30 105.2 0.1 5.7e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 Brix domain DUF2857 PF11198.8 GAP91208.1 - 0.14 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) UPF1_Zn_bind PF09416.10 GAP91209.1 - 5.5e-73 244.0 1.5 5.4e-72 240.7 0.9 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 GAP91209.1 - 6.9e-59 198.8 0.0 1.2e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 GAP91209.1 - 3.9e-52 177.6 1.3 1.1e-29 104.1 0.1 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 GAP91209.1 - 3.3e-33 113.8 0.0 6.5e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 GAP91209.1 - 3.1e-14 53.2 0.1 2.6e-13 50.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAP91209.1 - 1e-09 38.9 0.0 5.1e-09 36.6 0.0 2.2 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 GAP91209.1 - 2.2e-05 24.6 0.0 4.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 GAP91209.1 - 0.00011 22.2 0.0 0.00028 20.8 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 GAP91209.1 - 0.0014 17.9 0.1 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 GAP91209.1 - 0.0017 17.6 0.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DEAD PF00270.29 GAP91209.1 - 0.0037 17.0 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 GAP91209.1 - 0.004 16.7 0.0 0.11 12.0 0.0 2.3 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 GAP91209.1 - 0.011 16.0 0.0 0.041 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 GAP91209.1 - 0.026 13.9 0.0 0.074 12.4 0.0 1.7 1 0 0 1 1 1 0 KaiC Ribosomal_S13_N PF08069.12 GAP91209.1 - 0.062 13.3 0.8 0.33 11.0 0.0 2.6 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain PhoH PF02562.16 GAP91209.1 - 0.079 12.4 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 GAP91209.1 - 0.08 12.6 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 GAP91209.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 GAP91209.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 GAP91209.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 GAP91210.1 - 3.1e-14 52.8 0.0 6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 GAP91210.1 - 6.7e-05 23.3 0.0 0.00026 21.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain TPR_2 PF07719.17 GAP91210.1 - 0.00014 21.7 16.7 0.057 13.5 0.3 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat IstB_IS21 PF01695.17 GAP91210.1 - 0.004 16.9 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein TPR_19 PF14559.6 GAP91210.1 - 0.029 14.9 1.6 0.084 13.4 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NACHT PF05729.12 GAP91210.1 - 0.064 13.2 0.1 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ArsA_ATPase PF02374.15 GAP91210.1 - 0.16 11.1 0.0 0.37 9.9 0.0 1.6 1 0 0 1 1 1 0 Anion-transporting ATPase TPR_10 PF13374.6 GAP91210.1 - 0.17 11.8 3.7 0.45 10.5 0.6 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAP91210.1 - 1.2 9.1 9.2 25 4.9 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAP91210.1 - 4 7.8 15.6 0.23 11.8 1.6 4.6 4 1 2 6 6 6 0 Tetratricopeptide repeat Sugar_tr PF00083.24 GAP91211.1 - 2.8e-88 296.8 15.0 8.2e-45 153.5 2.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAP91211.1 - 8.3e-33 113.8 32.5 5.4e-31 107.8 25.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAP91211.1 - 0.00028 19.5 5.6 0.00028 19.5 5.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Asp_Glu_race PF01177.22 GAP91212.1 - 0.0021 17.9 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 2 Asp/Glu/Hydantoin racemase Actin PF00022.19 GAP91213.1 - 3.4e-99 332.2 0.0 2.5e-98 329.4 0.0 1.8 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 GAP91213.1 - 0.046 12.9 0.1 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative actin-like family MreB_Mbl PF06723.13 GAP91213.1 - 0.096 11.5 0.0 0.73 8.6 0.0 2.2 2 1 0 2 2 2 0 MreB/Mbl protein Pkinase PF00069.25 GAP91214.1 - 1.9e-65 220.9 0.0 2.6e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP91214.1 - 4.5e-31 108.1 0.0 7.1e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 GAP91214.1 - 0.016 14.2 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 GAP91214.1 - 0.033 13.5 0.0 0.064 12.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 GAP91214.1 - 0.063 13.2 0.1 0.32 10.9 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.21 GAP91215.1 - 5.9e-75 250.5 0.3 7e-75 250.3 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAP91215.1 - 3.6e-14 53.0 0.0 5.1e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 GAP91215.1 - 3.8e-13 49.3 0.0 4.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 GAP91215.1 - 2.8e-12 46.5 2.1 1.4e-08 34.3 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 GAP91215.1 - 3.6e-12 46.1 0.1 4.5e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 GAP91215.1 - 2.2e-11 43.6 0.1 2.9e-11 43.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 GAP91215.1 - 0.00039 20.5 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SpoOE-like PF09388.10 GAP91215.1 - 0.012 15.5 1.7 0.02 14.8 1.7 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Methyltrn_RNA_3 PF02598.17 GAP91215.1 - 0.024 14.1 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase 6PF2K PF01591.18 GAP91215.1 - 0.06 12.7 0.2 0.13 11.5 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF1325 PF07039.11 GAP91216.1 - 3.2e-32 111.4 0.0 5e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain CCDC53 PF10152.9 GAP91217.1 - 0.036 14.5 0.2 0.072 13.5 0.2 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Goodbye PF17109.5 GAP91217.1 - 0.051 14.0 0.1 0.28 11.6 0.0 2.3 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain AAA PF00004.29 GAP91218.1 - 2e-19 70.4 0.0 3.7e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP91218.1 - 0.00019 21.9 1.5 0.0011 19.4 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAP91218.1 - 0.0022 18.3 0.4 0.042 14.1 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GAP91218.1 - 0.0074 16.3 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 GAP91218.1 - 0.085 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zot PF05707.12 GAP91218.1 - 0.12 12.0 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) NB-ARC PF00931.22 GAP91218.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain CPT PF07931.12 GAP91218.1 - 0.28 11.0 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AA_permease_2 PF13520.6 GAP91219.1 - 1.2e-63 215.5 39.7 1.4e-63 215.2 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP91219.1 - 3e-17 62.4 35.0 3.8e-17 62.0 35.0 1.1 1 0 0 1 1 1 1 Amino acid permease RPA43_OB PF17875.1 GAP91220.1 - 1.1e-34 119.7 0.1 1.1e-34 119.7 0.1 3.6 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 GAP91220.1 - 0.00018 21.8 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 AF-4 PF05110.13 GAP91220.1 - 0.79 7.7 19.6 1.1 7.2 19.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sin_N PF04801.13 GAP91220.1 - 5.8 6.0 13.0 9.3 5.3 12.6 1.5 1 1 0 1 1 1 0 Sin-like protein conserved region TFIIA PF03153.13 GAP91220.1 - 6.7 6.6 22.8 11 5.9 22.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 GAP91220.1 - 7.5 5.8 29.4 13 5.1 29.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NmrA PF05368.13 GAP91221.1 - 9.4e-29 100.6 0.0 1.2e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP91221.1 - 6.9e-09 35.8 0.1 5.6e-08 32.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 GAP91221.1 - 1.1e-06 28.3 0.6 4.3e-05 23.1 0.3 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAP91221.1 - 1.1e-05 24.6 0.2 1.7e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 GAP91221.1 - 0.0011 18.2 0.1 0.0017 17.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 GAP91221.1 - 0.012 15.5 0.3 0.021 14.7 0.3 1.3 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 GAP91221.1 - 0.012 16.0 0.2 0.029 14.8 0.2 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 GAP91221.1 - 0.02 14.3 0.4 0.054 12.9 0.1 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Phage_Cox PF10743.9 GAP91221.1 - 0.14 12.3 0.1 0.48 10.6 0.0 1.7 1 1 1 2 2 2 0 Regulatory phage protein cox FliT PF05400.13 GAP91222.1 - 0.0057 17.4 2.4 0.0073 17.1 1.2 1.7 2 0 0 2 2 2 1 Flagellar protein FliT DAP10 PF07213.11 GAP91222.1 - 0.21 11.6 0.7 0.43 10.6 0.7 1.5 1 0 0 1 1 1 0 DAP10 membrane protein Pro_isomerase PF00160.21 GAP91223.1 - 1e-32 113.6 0.0 1.6e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 GAP91223.1 - 5e-15 55.1 0.0 9.6e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 GAP91224.1 - 3.1e-07 30.4 5.6 4.4e-07 29.9 5.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NDUF_B7 PF05676.13 GAP91226.1 - 4.8e-29 99.9 5.4 5.7e-29 99.6 5.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 GAP91226.1 - 0.011 15.7 2.0 0.013 15.5 1.4 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GTP_cyclohydro2 PF00925.20 GAP91228.1 - 5.5e-60 201.7 0.0 7.4e-60 201.2 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II Peptidase_S41 PF03572.18 GAP91229.1 - 2.1e-07 30.6 0.0 1.6e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase family S41 Nsp1_C PF05064.13 GAP91229.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region TRI5 PF06330.11 GAP91230.1 - 3.4e-17 62.4 0.3 4.5e-17 62.0 0.3 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.22 GAP91231.1 - 1.2e-37 129.8 0.0 1.5e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C14 PF00656.22 GAP91233.1 - 4.8e-33 115.2 0.0 8.2e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain PNP_UDP_1 PF01048.20 GAP91233.1 - 3.1e-10 39.7 0.0 7e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily zf-C2H2 PF00096.26 GAP91233.1 - 0.0018 18.6 5.8 1 10.0 1.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type PhyH PF05721.13 GAP91234.1 - 6.2e-26 92.0 0.0 8.3e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fapy_DNA_glyco PF01149.24 GAP91235.1 - 9.2e-34 116.5 0.1 3.5e-33 114.7 0.0 2.0 3 0 0 3 3 3 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 GAP91235.1 - 1.8e-20 72.7 0.0 3.2e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Ndc80_HEC PF03801.13 GAP91239.1 - 6.5e-63 210.9 0.2 1.4e-62 209.9 0.2 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family FliJ PF02050.16 GAP91239.1 - 0.0088 16.3 3.4 0.0088 16.3 3.4 4.3 2 2 2 4 4 4 3 Flagellar FliJ protein Filament PF00038.21 GAP91239.1 - 0.056 13.0 42.3 0.3 10.6 6.7 3.3 3 1 2 5 5 5 0 Intermediate filament protein Spc7 PF08317.11 GAP91239.1 - 0.059 12.2 38.3 0.27 10.1 14.8 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF2935 PF11155.8 GAP91239.1 - 0.3 11.4 8.2 0.059 13.7 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) DUF4795 PF16043.5 GAP91239.1 - 0.37 10.3 30.8 0.23 11.0 8.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) THDPS_N_2 PF14805.6 GAP91239.1 - 0.58 10.4 7.4 0.049 13.9 0.9 2.7 2 1 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF948 PF06103.11 GAP91239.1 - 0.58 10.4 9.5 5.5 7.3 0.6 4.4 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 GAP91239.1 - 1.1 9.3 40.6 0.047 13.8 9.7 3.9 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 GAP91239.1 - 1.2 8.6 19.4 1.4 8.4 3.5 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Fungal_TACC PF12709.7 GAP91239.1 - 1.3 9.5 0.0 1.3 9.5 0.0 5.5 4 1 2 6 6 6 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 GAP91239.1 - 4.1 6.7 28.0 1 8.7 7.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) RPW8 PF05659.11 GAP91239.1 - 5 6.8 16.0 3.5 7.3 4.7 3.7 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 APG6_N PF17675.1 GAP91239.1 - 5.1 7.6 56.0 0.21 12.1 4.8 4.6 2 2 2 4 4 4 0 Apg6 coiled-coil region Atg14 PF10186.9 GAP91239.1 - 7 5.6 22.8 1.1 8.3 6.5 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mito_fiss_reg PF05308.11 GAP91239.1 - 7.3 6.6 10.3 0.76 9.8 4.8 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator ESCRT-II PF05871.12 GAP91240.1 - 3.7e-55 186.0 0.0 1.1e-54 184.5 0.0 1.7 2 0 0 2 2 2 1 ESCRT-II complex subunit RTT107_BRCT_5 PF16770.5 GAP91241.1 - 2.8e-34 117.0 0.0 6.1e-31 106.3 0.0 4.5 5 0 0 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 GAP91241.1 - 1.7e-31 107.9 1.9 3.3e-19 68.6 0.2 4.6 4 0 0 4 4 4 4 twin BRCT domain BRCT_2 PF16589.5 GAP91241.1 - 2.5e-28 98.3 0.0 1e-05 25.9 0.0 6.1 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 GAP91241.1 - 5.9e-27 93.9 0.0 7.9e-09 35.8 0.0 6.3 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 GAP91241.1 - 3.2e-11 43.4 2.4 0.023 15.0 0.0 5.3 6 0 0 6 6 6 3 DNA ligase 3 BRCT domain Pkinase PF00069.25 GAP91242.1 - 1.8e-17 63.6 0.0 2.3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP91242.1 - 1.8e-08 34.0 0.0 3.1e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP91242.1 - 0.053 13.4 0.2 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 GAP91242.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SurE PF01975.17 GAP91243.1 - 4.4e-49 166.9 0.0 6.3e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE TTL PF03133.15 GAP91243.1 - 1e-47 162.7 0.0 3.9e-47 160.8 0.0 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 GAP91243.1 - 0.0011 18.3 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp Glyco_trans_4_4 PF13579.6 GAP91243.1 - 0.43 11.0 4.9 1.3 9.4 4.0 2.2 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain DASH_Duo1 PF08651.10 GAP91245.1 - 1.5e-31 108.0 0.5 2e-31 107.6 0.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DASH_Dad2 PF08654.10 GAP91245.1 - 0.024 15.0 1.5 0.047 14.1 1.5 1.5 1 1 0 1 1 1 0 DASH complex subunit Dad2 RNA_pol_Rpc4 PF05132.14 GAP91245.1 - 3.3 8.1 7.4 3.3 8.1 1.0 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 RNase_H2-Ydr279 PF09468.10 GAP91246.1 - 2.4e-38 131.8 0.6 8.4e-38 130.1 0.0 2.2 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 GAP91246.1 - 3e-25 88.3 0.0 8.4e-25 86.8 0.0 1.8 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain FSA_C PF10479.9 GAP91246.1 - 0.0073 14.5 5.1 0.013 13.7 5.1 1.3 1 0 0 1 1 1 1 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 GAP91246.1 - 1.1 7.2 13.1 1.8 6.5 13.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2052 PF09747.9 GAP91246.1 - 1.5 8.9 10.7 1.1 9.4 2.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) zf-primase PF09329.11 GAP91247.1 - 3.2e-17 62.1 0.3 5.4e-17 61.3 0.3 1.4 1 0 0 1 1 1 1 Primase zinc finger Aim21 PF11489.8 GAP91248.1 - 6e-186 620.5 67.4 6e-186 620.5 67.4 2.1 1 1 1 2 2 2 1 Altered inheritance of mitochondria protein 21 Cg6151-P PF10233.9 GAP91249.1 - 4.9e-40 136.4 15.1 5.8e-40 136.1 15.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P LMF1 PF06762.14 GAP91249.1 - 0.64 9.1 2.9 0.85 8.7 2.9 1.2 1 0 0 1 1 1 0 Lipase maturation factor TMEM169 PF15052.6 GAP91249.1 - 1.3 9.2 10.0 0.11 12.7 3.9 1.9 1 1 1 2 2 2 0 TMEM169 protein family PRA1 PF03208.19 GAP91249.1 - 3 7.5 16.0 0.35 10.5 1.2 2.1 1 1 1 2 2 2 0 PRA1 family protein p450 PF00067.22 GAP91250.1 - 4.6e-31 108.1 0.0 5.2e-30 104.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DOPA_dioxygen PF08883.11 GAP91251.1 - 1.7e-43 147.1 0.3 2.2e-43 146.8 0.3 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Glycos_transf_2 PF00535.26 GAP91251.1 - 0.16 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 HLH PF00010.26 GAP91252.1 - 1.7e-17 63.1 0.1 4.9e-16 58.4 0.1 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Dfp1_Him1_M PF08630.10 GAP91253.1 - 6.5e-39 133.0 0.8 3.2e-38 130.8 0.1 2.6 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 GAP91253.1 - 1.9e-20 72.7 0.6 3.3e-20 71.9 0.6 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 GAP91253.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain Ank_2 PF12796.7 GAP91254.1 - 1.2e-24 86.7 0.1 7.1e-14 52.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP91254.1 - 2.2e-14 53.3 0.2 3.4e-06 27.2 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAP91254.1 - 5.2e-14 52.0 0.2 4.3e-05 23.8 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 GAP91254.1 - 7.2e-11 42.4 0.0 1e-06 29.1 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP91254.1 - 2.8e-10 39.5 0.0 0.021 15.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Pyr_redox_2 PF07992.14 GAP91256.1 - 8.9e-23 80.9 0.0 1.1e-22 80.7 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP91256.1 - 0.0022 18.5 4.2 0.083 13.5 0.8 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP91256.1 - 0.0053 16.8 2.3 3.3 7.7 0.0 3.2 2 2 1 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 GAP91256.1 - 0.011 15.3 5.2 1.4 8.4 0.0 2.9 2 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP91256.1 - 0.022 13.8 1.1 0.16 11.1 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 GAP91256.1 - 0.042 13.0 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 GAP91256.1 - 0.052 12.6 0.9 4.6 6.2 0.1 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 GAP91256.1 - 0.41 9.9 2.9 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 GAP91257.1 - 9.1e-11 41.3 0.0 1.4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP91257.1 - 7.7e-09 35.5 8.0 1.5e-08 34.6 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.17 GAP91257.1 - 0.003 17.5 5.5 0.003 17.5 5.5 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein zf-C2H2_4 PF13894.6 GAP91258.1 - 2.7e-15 55.7 21.8 0.0065 17.2 1.0 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP91258.1 - 5.8e-13 48.8 18.3 3.8e-07 30.2 0.6 4.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP91258.1 - 1.3e-11 44.5 21.4 2.8e-06 27.5 1.2 4.6 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 GAP91258.1 - 3.2e-10 39.9 28.5 0.011 16.2 2.1 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 GAP91258.1 - 3.1e-07 30.6 18.0 0.012 15.9 1.6 5.0 2 2 3 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 GAP91258.1 - 6.4e-06 26.4 23.4 0.18 12.3 0.7 5.7 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 GAP91258.1 - 2.2e-05 24.3 29.5 0.00072 19.5 3.0 5.1 6 0 0 6 6 5 2 C2H2-type zinc finger HypA PF01155.19 GAP91258.1 - 0.0045 17.0 0.1 0.0045 17.0 0.1 2.7 2 2 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 GAP91258.1 - 0.013 15.8 0.8 0.013 15.8 0.8 4.4 3 2 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding HTH_CodY PF08222.11 GAP91258.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain Trm112p PF03966.16 GAP91258.1 - 0.028 15.0 0.8 0.61 10.7 0.2 2.7 2 2 0 2 2 2 0 Trm112p-like protein zf-C2H2_3rep PF18868.1 GAP91258.1 - 0.097 13.4 11.5 0.29 11.8 1.5 2.6 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_ZIC PF18366.1 GAP91258.1 - 0.14 12.3 3.4 12 6.1 0.0 4.0 4 0 0 4 4 4 0 Zic proteins zinc finger domain zinc_ribbon_15 PF17032.5 GAP91258.1 - 0.52 11.1 9.3 1.8 9.4 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon family zf-CHY PF05495.12 GAP91258.1 - 1.1 9.8 19.7 3.7 8.1 7.3 2.8 2 2 0 2 2 2 0 CHY zinc finger zf-DBF PF07535.12 GAP91258.1 - 1.1 9.4 13.3 1.6 8.9 1.0 3.7 4 0 0 4 4 4 0 DBF zinc finger TRAF6_Z2 PF18048.1 GAP91258.1 - 1.2 9.3 10.3 0.91 9.7 0.3 4.1 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_11 PF16622.5 GAP91258.1 - 1.4 8.8 22.4 1.3 8.9 1.9 5.1 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-LYAR PF08790.11 GAP91258.1 - 1.5 8.8 7.6 6 6.9 0.1 4.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C3HC4_3 PF13920.6 GAP91258.1 - 2.6 8.0 6.9 10 6.1 1.4 3.8 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 GAP91258.1 - 5.1 7.3 19.7 19 5.4 0.7 4.8 2 2 2 4 4 4 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 GAP91258.1 - 6.3 6.8 15.9 2.8 8.0 0.7 4.6 4 1 0 4 4 4 0 zinc-finger of a C2HC-type AKAP95 PF04988.12 GAP91258.1 - 7.1 6.8 14.1 1.5 9.1 0.9 3.7 3 2 2 5 5 4 0 A-kinase anchoring protein 95 (AKAP95) APH PF01636.23 GAP91259.1 - 8.6e-14 52.0 0.1 5.7e-09 36.3 0.2 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Asp_Glu_race PF01177.22 GAP91261.1 - 5.2e-23 82.1 0.0 6.4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 GAP91261.1 - 0.095 12.3 0.1 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 Arylmalonate decarboxylase Methyltransf_2 PF00891.18 GAP91262.1 - 4e-18 65.5 0.0 5.6e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain APG12 PF04110.13 GAP91263.1 - 7.5e-27 93.6 0.0 9.5e-27 93.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 GAP91263.1 - 0.00011 22.4 0.0 0.00014 22.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 GAP91264.1 - 2.5e-103 345.0 1.8 2.9e-103 344.8 1.8 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 GAP91264.1 - 4.5e-08 32.9 0.3 6.9e-08 32.2 0.3 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 GAP91264.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) FAD_binding_4 PF01565.23 GAP91265.1 - 1.9e-18 66.6 3.9 1.9e-18 66.6 3.9 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAP91265.1 - 2.9e-09 36.9 0.4 8.7e-09 35.3 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 GAP91265.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Senescence PF06911.12 GAP91266.1 - 0.00098 19.5 4.8 0.0013 19.1 4.8 1.1 1 0 0 1 1 1 1 Senescence-associated protein Chlorosome_CsmC PF11098.8 GAP91266.1 - 0.067 13.2 7.1 0.093 12.7 7.1 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C FAM25 PF15825.5 GAP91266.1 - 0.19 12.1 4.4 2.3 8.6 0.5 2.1 1 1 1 2 2 2 0 FAM25 family Collagen_mid PF15984.5 GAP91266.1 - 0.24 11.1 14.8 0.38 10.5 3.6 2.1 1 1 1 2 2 2 0 Bacterial collagen, middle region VPS13_C PF16909.5 GAP91266.1 - 0.38 10.5 4.4 0.32 10.7 1.9 1.9 1 1 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal dCMP_cyt_deam_1 PF00383.23 GAP91267.1 - 1.2e-06 28.4 0.0 2.5e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 GAP91267.1 - 0.00075 19.3 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 GAP91267.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.7 3 1 0 3 3 3 0 Bd3614-like deaminase EF_assoc_2 PF08356.12 GAP91269.1 - 5e-34 116.1 0.0 1.1e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 GAP91269.1 - 6.8e-31 105.7 0.1 1.5e-30 104.6 0.1 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 GAP91269.1 - 1.5e-22 80.0 0.0 4.3e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 GAP91269.1 - 1.2e-13 51.3 0.0 1e-08 35.4 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 GAP91269.1 - 1.2e-07 32.1 0.3 0.0006 20.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 GAP91269.1 - 8.3e-07 28.1 3.8 0.011 15.2 0.8 2.7 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 GAP91269.1 - 1e-06 28.8 0.0 0.0016 18.5 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_6 PF13405.6 GAP91269.1 - 2e-05 24.1 6.3 0.055 13.4 0.9 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_16 PF13191.6 GAP91269.1 - 7.1e-05 23.3 0.1 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 GAP91269.1 - 8.1e-05 22.9 0.0 0.65 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 GAP91269.1 - 9e-05 22.1 0.1 0.089 12.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 GAP91269.1 - 0.0001 22.4 0.1 0.22 11.5 0.2 3.0 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 GAP91269.1 - 0.00013 22.0 0.3 1.8 8.4 0.1 3.3 2 1 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 GAP91269.1 - 0.00044 19.9 0.0 3.2 7.2 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 GAP91269.1 - 0.00069 20.1 0.0 1.3 9.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_24 PF13479.6 GAP91269.1 - 0.0018 18.0 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAP91269.1 - 0.0025 18.2 0.0 0.43 11.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 GAP91269.1 - 0.0031 17.4 0.0 3 7.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain EF-hand_10 PF14788.6 GAP91269.1 - 0.0039 17.0 1.4 0.061 13.2 0.1 2.5 2 0 0 2 2 2 1 EF hand DUF815 PF05673.13 GAP91269.1 - 0.016 14.4 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 GAP91269.1 - 0.016 14.9 0.0 0.67 9.7 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 GAP91269.1 - 0.018 15.3 0.0 5.5 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 GAP91269.1 - 0.03 14.2 0.0 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 GAP91269.1 - 0.046 14.3 0.0 2 9.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain EF-hand_5 PF13202.6 GAP91269.1 - 0.05 13.1 7.3 0.86 9.2 2.6 2.7 2 0 0 2 2 2 0 EF hand Septin PF00735.18 GAP91269.1 - 0.053 12.8 0.0 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 GAP91269.1 - 0.054 13.0 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 GAP91269.1 - 0.13 12.4 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 GAP91269.1 - 0.17 11.4 0.0 14 5.1 0.0 2.7 2 1 0 2 2 2 0 ADP-ribosylation factor family IIGP PF05049.13 GAP91269.1 - 0.18 10.9 0.0 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_23 PF13476.6 GAP91269.1 - 0.21 12.1 0.2 16 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAP91269.1 - 0.26 10.5 0.0 11 5.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) EF-hand_8 PF13833.6 GAP91269.1 - 0.31 10.9 3.3 7.2 6.6 0.7 2.6 2 0 0 2 2 2 0 EF-hand domain pair WD40 PF00400.32 GAP91270.1 - 7.1e-12 45.7 9.1 0.00045 21.0 0.1 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP91270.1 - 5.1e-09 36.3 0.0 0.0065 16.8 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 GAP91270.1 - 8.2e-05 22.6 0.0 0.00059 19.8 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A YpsA PF06908.11 GAP91270.1 - 0.22 11.5 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family Arrestin_C PF02752.22 GAP91271.1 - 7.2e-18 65.3 0.0 1.6e-17 64.2 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 GAP91271.1 - 6.1e-15 55.6 0.0 1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 GAP91271.1 - 0.029 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like PH PF00169.29 GAP91272.1 - 0.00018 22.0 0.0 0.00033 21.1 0.0 1.5 1 0 0 1 1 1 1 PH domain DCB PF16213.5 GAP91272.1 - 0.15 11.8 0.5 0.31 10.7 0.5 1.5 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Clr5 PF14420.6 GAP91273.1 - 4.3e-13 49.3 2.8 1e-12 48.0 2.8 1.7 1 0 0 1 1 1 1 Clr5 domain SR-25 PF10500.9 GAP91273.1 - 1.9 8.1 8.6 3.5 7.2 8.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PRIMA1 PF16101.5 GAP91273.1 - 2.6 8.1 5.2 8.2 6.5 5.2 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EthD PF07110.11 GAP91274.1 - 0.096 13.8 0.0 0.1 13.7 0.0 1.2 1 0 0 1 1 1 0 EthD domain Lipase_GDSL PF00657.22 GAP91275.1 - 3.6e-11 43.4 0.1 4.8e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 GAP91275.1 - 1.2e-06 29.1 4.9 3.2e-06 27.7 4.9 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RNase_H PF00075.24 GAP91276.1 - 1.3e-12 48.1 0.2 3.8e-11 43.3 0.2 2.2 1 1 0 1 1 1 1 RNase H Peptidase_S66 PF02016.15 GAP91278.1 - 1.6e-26 92.7 0.0 2.3e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 GAP91278.1 - 5.3e-22 78.7 0.0 8e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain Abhydrolase_2 PF02230.16 GAP91279.1 - 1.7e-21 77.0 0.0 1.8e-15 57.3 0.0 2.8 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAP91279.1 - 0.0047 16.4 0.0 0.0075 15.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Sulfatase PF00884.23 GAP91280.1 - 9.8e-59 199.2 0.3 1.2e-58 198.9 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 GAP91280.1 - 5.2e-09 36.2 1.6 1.1e-07 31.8 1.7 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 GAP91280.1 - 0.002 18.4 1.2 0.0043 17.3 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 GAP91280.1 - 0.16 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.24 GAP91281.1 - 1.1e-75 255.3 12.0 1.5e-75 254.9 12.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP91281.1 - 3e-17 62.6 37.0 3.9e-10 39.2 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 GAP91282.1 - 1.5e-09 38.3 0.1 2.6e-06 27.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP91282.1 - 1.6e-07 31.7 0.2 0.06 13.9 0.0 3.8 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Helo_like_N PF17111.5 GAP91282.1 - 0.00049 19.5 0.6 0.0013 18.2 0.6 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank PF00023.30 GAP91282.1 - 0.0043 17.5 0.2 28 5.4 0.2 3.8 3 0 0 3 3 3 1 Ankyrin repeat SesA PF17107.5 GAP91282.1 - 0.036 14.3 0.2 11 6.2 0.0 2.6 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Hrs_helical PF12210.8 GAP91282.1 - 0.087 13.4 0.2 0.3 11.7 0.0 1.9 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate UPF0029 PF01205.19 GAP91283.1 - 5.1e-25 87.9 0.0 1.1e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Methyltransf_23 PF13489.6 GAP91284.1 - 2.6e-16 59.9 0.0 5.1e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP91284.1 - 0.00074 20.2 0.0 0.65 10.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 GAP91284.1 - 0.0027 18.4 0.0 0.87 10.3 0.0 3.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP91284.1 - 0.14 12.8 0.0 14 6.4 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Rsm22 PF09243.10 GAP91285.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 MFS_1 PF07690.16 GAP91287.1 - 8.2e-30 103.9 21.3 8.2e-30 103.9 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Na_H_Exchanger PF00999.21 GAP91289.1 - 1.2e-16 60.5 18.5 1.3e-15 57.1 18.6 1.9 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2070 PF09843.9 GAP91289.1 - 0.048 12.0 0.1 0.048 12.0 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Not1 PF04054.15 GAP91290.1 - 3.5e-92 309.1 0.0 9.9e-92 307.7 0.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 GAP91290.1 - 3.1e-89 298.2 1.8 7.1e-89 297.0 1.8 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 GAP91290.1 - 6.7e-49 165.6 2.2 1.5e-48 164.4 2.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 GAP91290.1 - 1.2e-42 145.3 0.0 3.3e-42 143.8 0.0 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 GAP91290.1 - 1.6e-34 119.2 3.2 2.2e-34 118.7 0.5 2.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat FAD_binding_4 PF01565.23 GAP91291.1 - 4.3e-20 71.9 0.4 7.9e-20 71.0 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP91291.1 - 1e-13 51.1 0.1 2e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DinB PF05163.12 GAP91292.1 - 0.19 11.6 0.2 0.45 10.4 0.1 1.6 1 1 1 2 2 2 0 DinB family His_Phos_1 PF00300.22 GAP91293.1 - 0.0029 17.3 0.8 0.02 14.6 0.8 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FUSC_2 PF13515.6 GAP91294.1 - 1.4e-14 54.3 29.9 2.8e-12 46.8 2.0 3.3 3 0 0 3 3 3 2 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 GAP91294.1 - 2.5e-06 26.8 0.8 2.5e-06 26.8 0.8 3.3 2 1 1 3 3 3 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 GAP91294.1 - 4e-05 23.6 0.0 8.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 DUF1097 PF06496.11 GAP91294.1 - 0.19 11.8 20.3 0.49 10.5 2.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) ALMT PF11744.8 GAP91294.1 - 1.8 7.3 3.6 0.62 8.8 0.0 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter NTF2 PF02136.20 GAP91295.1 - 1.3e-16 61.3 0.1 1.4e-16 61.1 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain HECT PF00632.25 GAP91296.1 - 7.6e-81 271.9 0.0 1.3e-80 271.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 GAP91296.1 - 0.0017 18.0 1.0 0.0048 16.6 1.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Sugar_tr PF00083.24 GAP91297.1 - 1.1e-103 347.5 18.9 1.5e-103 347.1 18.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Sulfatase PF00884.23 GAP91297.1 - 7.9e-38 130.6 0.3 1.3e-36 126.6 0.0 2.4 1 1 1 2 2 2 1 Sulfatase MFS_1 PF07690.16 GAP91297.1 - 1.8e-25 89.6 41.0 2e-19 69.8 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAP91297.1 - 5.8e-06 25.0 1.7 5.8e-06 25.0 1.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 GAP91297.1 - 0.0037 17.0 3.8 0.0037 17.0 3.8 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF4976 PF16347.5 GAP91297.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Zn_clus PF00172.18 GAP91298.1 - 4e-06 26.9 10.5 6.9e-06 26.1 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 GAP91299.1 - 4.3e-62 210.4 0.0 5.6e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 GAP91300.1 - 2.6e-27 95.9 0.0 4.2e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAP91300.1 - 3.7e-27 95.3 0.0 6.3e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAP91300.1 - 3.3e-10 40.6 0.0 1.8e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain bact-PGI_C PF10432.9 GAP91300.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal SIS domain DUF3439 PF11921.8 GAP91300.1 - 0.7 9.9 3.7 0.61 10.1 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RRM_1 PF00076.22 GAP91301.1 - 1.1e-84 278.2 8.2 3.7e-22 77.9 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 GAP91301.1 - 2.4e-26 91.7 0.2 9.5e-26 89.8 0.2 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 GAP91301.1 - 1.9e-09 37.2 0.0 0.0064 16.1 0.0 5.1 2 1 3 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 GAP91301.1 - 1.9e-08 34.0 0.1 0.0004 20.2 0.0 4.3 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_3 PF08777.11 GAP91301.1 - 0.0001 22.3 6.8 0.61 10.2 1.4 5.0 5 0 0 5 5 5 1 RNA binding motif RRM_7 PF16367.5 GAP91301.1 - 0.00016 21.7 0.3 2 8.6 0.0 5.1 4 1 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 GAP91301.1 - 0.00024 21.0 1.4 3.8 7.6 0.1 4.4 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 GAP91301.1 - 0.0018 18.8 7.8 0.12 12.8 0.6 3.5 3 0 0 3 3 3 1 Heat induced stress protein YflT MecA PF05389.12 GAP91301.1 - 0.014 15.0 1.4 0.014 15.0 1.4 1.9 1 1 1 2 2 2 0 Negative regulator of genetic competence (MecA) OB_RNB PF08206.11 GAP91301.1 - 0.19 11.4 3.1 10 5.9 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain DHHA1 PF02272.19 GAP91301.1 - 1.1 9.6 6.4 1.1 9.6 0.2 2.9 3 0 0 3 3 3 0 DHHA1 domain DUF16 PF01519.16 GAP91302.1 - 0.00065 20.1 0.2 0.0019 18.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function DUF16 CLZ PF16526.5 GAP91302.1 - 0.0027 18.0 3.6 2.6 8.4 0.2 3.8 4 1 1 5 5 4 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 GAP91302.1 - 0.003 18.0 0.5 0.0077 16.7 0.5 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 GAP91302.1 - 0.0051 15.9 2.1 0.0051 15.9 2.1 1.7 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 GAP91302.1 - 0.0069 16.4 0.8 0.016 15.2 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 GAP91302.1 - 0.01 15.8 0.7 0.062 13.3 0.2 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 GAP91302.1 - 0.011 15.5 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH XhlA PF10779.9 GAP91302.1 - 0.012 15.8 0.7 0.089 13.0 0.3 2.5 3 0 0 3 3 2 0 Haemolysin XhlA LPP PF04728.13 GAP91302.1 - 0.012 16.0 0.7 0.042 14.2 0.7 2.0 1 0 0 1 1 1 0 Lipoprotein leucine-zipper BLOC1_2 PF10046.9 GAP91302.1 - 0.041 14.2 3.7 0.16 12.3 1.3 3.1 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 GAP91302.1 - 0.053 14.0 2.7 0.064 13.7 0.0 2.5 2 0 0 2 2 1 0 Cell division protein ZapB UvrA_DNA-bind PF17755.1 GAP91302.1 - 0.055 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 UvrA DNA-binding domain EzrA PF06160.12 GAP91302.1 - 0.071 11.3 3.5 0.057 11.6 0.5 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Prefoldin_2 PF01920.20 GAP91302.1 - 0.072 13.1 3.0 0.84 9.6 0.3 3.0 2 1 1 3 3 3 0 Prefoldin subunit TLE_N PF03920.15 GAP91302.1 - 0.077 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DUF4164 PF13747.6 GAP91302.1 - 0.089 13.1 1.8 0.45 10.8 0.1 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4164) DivIC PF04977.15 GAP91302.1 - 0.09 12.6 0.8 0.29 10.9 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4795 PF16043.5 GAP91302.1 - 0.091 12.3 1.3 0.14 11.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Cnn_1N PF07989.11 GAP91302.1 - 0.1 12.8 0.4 0.26 11.5 0.0 1.8 2 0 0 2 2 1 0 Centrosomin N-terminal motif 1 DUF2730 PF10805.8 GAP91302.1 - 0.11 12.6 0.5 0.25 11.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) RasGAP_C PF03836.15 GAP91302.1 - 0.19 11.8 5.6 2.5 8.3 1.8 2.4 2 0 0 2 2 2 0 RasGAP C-terminus DUF3552 PF12072.8 GAP91302.1 - 0.23 10.9 2.4 0.19 11.1 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Enkurin PF13864.6 GAP91302.1 - 0.26 11.7 4.7 7.2 7.1 0.1 2.8 3 0 0 3 3 2 0 Calmodulin-binding DUF2205 PF10224.9 GAP91302.1 - 0.27 11.3 1.3 0.4 10.7 0.2 1.8 2 0 0 2 2 2 0 Short coiled-coil protein Allexi_40kDa PF05549.11 GAP91302.1 - 0.31 10.5 2.7 0.57 9.7 2.7 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Syntaxin-6_N PF09177.11 GAP91302.1 - 0.43 11.2 5.3 0.44 11.1 0.8 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Uds1 PF15456.6 GAP91302.1 - 0.5 10.5 4.5 1.7 8.8 1.2 2.7 2 1 0 2 2 2 0 Up-regulated During Septation TRPM_tetra PF16519.5 GAP91302.1 - 1.5 9.0 3.1 20 5.3 0.1 2.4 1 1 1 2 2 2 0 Tetramerisation domain of TRPM Fmp27_WPPW PF10359.9 GAP91302.1 - 1.6 7.5 6.7 0.79 8.5 4.6 1.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain TPR_MLP1_2 PF07926.12 GAP91302.1 - 3 7.9 6.4 1.6 8.8 0.1 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein TPR_10 PF13374.6 GAP91303.1 - 0.0063 16.3 0.8 8.6 6.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAP91303.1 - 0.18 12.5 0.0 1.8 9.4 0.0 2.5 1 1 0 1 1 1 0 Tetratricopeptide repeat GMC_oxred_N PF00732.19 GAP91305.1 - 6.3e-57 193.2 0.0 8.8e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP91305.1 - 7.7e-30 104.3 0.0 1.6e-29 103.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAP91305.1 - 1.1e-07 31.4 0.9 0.005 16.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAP91305.1 - 1.1e-05 25.2 2.2 8.6e-05 22.3 2.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAP91305.1 - 0.00012 21.5 0.1 0.0025 17.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP91305.1 - 0.00016 21.8 0.3 0.00044 20.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP91305.1 - 0.0005 19.4 0.1 0.016 14.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 GAP91305.1 - 0.0061 16.8 0.2 0.025 14.8 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain Thi4 PF01946.17 GAP91305.1 - 0.0096 15.2 0.2 0.017 14.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family PALP PF00291.25 GAP91305.1 - 0.011 15.1 0.0 0.052 13.0 0.0 1.9 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme FAD_binding_3 PF01494.19 GAP91305.1 - 0.017 14.4 0.1 0.13 11.4 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 GAP91305.1 - 0.03 13.0 0.2 0.072 11.8 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 GAP91305.1 - 0.039 14.0 0.3 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 GAP91305.1 - 0.057 12.5 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAP91305.1 - 0.083 13.5 0.3 0.53 10.9 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ceramidase PF05875.12 GAP91306.1 - 3.2e-56 190.7 1.1 3.5e-56 190.5 1.1 1.0 1 0 0 1 1 1 1 Ceramidase DUF2070 PF09843.9 GAP91306.1 - 6.2 5.0 8.6 8.2 4.6 8.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TPR_12 PF13424.6 GAP91307.1 - 2.6e-06 27.6 4.8 0.0004 20.6 0.8 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Peptidase_C97 PF05903.14 GAP91307.1 - 0.00014 21.7 0.3 0.00033 20.5 0.3 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain TPR_7 PF13176.6 GAP91307.1 - 0.00027 20.7 4.6 0.034 14.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAP91307.1 - 0.0017 18.3 2.8 1.3 9.3 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAP91307.1 - 0.0083 16.6 6.0 1.4 9.5 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 GAP91307.1 - 0.033 15.0 6.1 1.5 9.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAP91307.1 - 0.05 14.3 2.5 3.4 8.5 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAP91307.1 - 0.066 13.9 2.2 4.8 7.9 1.2 3.3 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAP91307.1 - 0.47 10.4 3.7 3.2 7.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAP91307.1 - 2.9 7.9 8.0 3.4 7.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3341 PF11821.8 GAP91308.1 - 0.17 11.5 2.2 0.34 10.5 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) GST_N PF02798.20 GAP91309.1 - 3.3e-14 53.0 0.1 7.3e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP91309.1 - 1.2e-13 51.1 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAP91309.1 - 9.1e-12 45.2 0.0 1.7e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAP91309.1 - 9.1e-10 38.6 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAP91309.1 - 3.1e-09 37.0 0.0 7.9e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP91309.1 - 4e-07 30.0 0.1 7.8e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3791 PF12668.7 GAP91309.1 - 0.039 14.0 0.2 0.074 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) DUF4301 PF14134.6 GAP91309.1 - 0.12 11.2 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) Aconitase PF00330.20 GAP91310.1 - 1.1e-106 357.6 0.1 9.8e-106 354.5 0.1 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 GAP91310.1 - 2.8e-19 69.7 0.0 5.3e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain BLOC1_2 PF10046.9 GAP91311.1 - 0.00041 20.6 4.3 0.00041 20.6 4.3 3.0 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 GAP91311.1 - 0.00085 19.7 10.4 0.011 16.2 0.9 2.9 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 GAP91311.1 - 0.001 17.8 11.2 0.0012 17.6 11.2 1.2 1 0 0 1 1 1 1 AAA domain OmpH PF03938.14 GAP91311.1 - 0.0013 19.1 24.1 0.074 13.4 4.9 3.2 2 1 1 3 3 3 2 Outer membrane protein (OmpH-like) IFT20 PF14931.6 GAP91311.1 - 0.0094 16.1 13.1 0.03 14.5 6.1 2.6 2 0 0 2 2 2 1 Intraflagellar transport complex B, subunit 20 Baculo_PEP_C PF04513.12 GAP91311.1 - 0.021 14.9 8.4 0.35 10.9 0.4 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHR10 PF18595.1 GAP91311.1 - 0.027 14.5 29.0 0.95 9.5 23.9 3.6 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF948 PF06103.11 GAP91311.1 - 0.038 14.2 6.9 0.41 10.9 0.6 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.6 GAP91311.1 - 0.071 12.8 16.5 0.19 11.4 1.4 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) Spc24 PF08286.11 GAP91311.1 - 0.098 12.9 17.8 0.1 12.9 3.9 3.3 2 1 0 3 3 3 0 Spc24 subunit of Ndc80 Fez1 PF06818.15 GAP91311.1 - 0.14 12.6 23.4 0.09 13.2 19.3 2.4 2 1 1 3 3 3 0 Fez1 DUF4407 PF14362.6 GAP91311.1 - 0.17 11.2 19.4 1 8.6 19.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FliD_C PF07195.12 GAP91311.1 - 0.28 10.6 4.4 3 7.2 0.3 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ATP-synt_F PF01990.17 GAP91311.1 - 0.3 11.4 1.9 0.69 10.3 0.1 2.3 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit MbeD_MobD PF04899.12 GAP91311.1 - 0.57 10.3 5.6 4 7.6 1.4 3.0 3 0 0 3 3 2 0 MbeD/MobD like Bacillus_HBL PF05791.11 GAP91311.1 - 0.68 9.7 6.5 1.2 9.0 1.2 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF5082 PF16888.5 GAP91311.1 - 0.8 10.0 9.4 0.36 11.1 3.7 2.7 2 1 0 3 3 2 0 Domain of unknown function (DUF5082) COG5 PF10392.9 GAP91311.1 - 1.1 9.4 11.7 0.48 10.6 0.5 2.8 2 1 1 3 3 3 0 Golgi transport complex subunit 5 YabA PF06156.13 GAP91311.1 - 1.4 9.6 15.9 7.8 7.2 2.7 3.4 2 1 1 3 3 3 0 Initiation control protein YabA V_ATPase_I PF01496.19 GAP91311.1 - 1.5 6.6 7.3 0.63 7.9 5.2 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 GAP91311.1 - 1.6 7.6 27.5 0.65 8.8 6.3 2.7 2 1 1 3 3 3 0 Spc7 kinetochore protein Prefoldin PF02996.17 GAP91311.1 - 1.6 8.6 15.0 4.7 7.1 2.1 3.0 2 1 0 2 2 2 0 Prefoldin subunit KxDL PF10241.9 GAP91311.1 - 1.7 9.0 13.2 0.33 11.2 1.5 3.1 3 1 1 4 4 3 0 Uncharacterized conserved protein Laminin_II PF06009.12 GAP91311.1 - 1.8 8.6 15.5 1.1 9.2 1.4 2.9 3 0 0 3 3 3 0 Laminin Domain II ADIP PF11559.8 GAP91311.1 - 1.8 8.6 20.7 0.35 10.9 5.4 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 GAP91311.1 - 2 8.5 19.7 0.28 11.2 4.5 2.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p PIN_6 PF17146.4 GAP91311.1 - 2 9.0 5.8 4.6 7.8 0.1 3.0 2 1 1 3 3 3 0 PIN domain of ribonuclease SlyX PF04102.12 GAP91311.1 - 2.6 8.7 22.9 1.2 9.8 5.4 4.4 4 1 0 4 4 3 0 SlyX PRKG1_interact PF15898.5 GAP91311.1 - 2.8 8.9 21.8 0.16 12.9 11.2 3.3 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain Noelin-1 PF12308.8 GAP91311.1 - 3 7.9 6.6 7.3 6.6 0.6 2.9 2 1 1 3 3 3 0 Neurogenesis glycoprotein FlaC_arch PF05377.11 GAP91311.1 - 3.5 8.1 7.1 24 5.4 0.3 3.7 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.13 GAP91311.1 - 3.6 7.1 12.2 1.3 8.5 1.6 2.8 3 0 0 3 3 3 0 fzo-like conserved region kleA_kleC PF17383.2 GAP91311.1 - 5.5 7.4 11.4 17 5.8 0.5 3.4 2 2 1 3 3 3 0 Uncharacterized KorC regulated protein A MCU PF04678.13 GAP91311.1 - 6 6.9 15.9 4 7.5 6.6 2.7 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Exonuc_VII_L PF02601.15 GAP91311.1 - 6.9 6.2 18.9 1.7e+02 1.6 18.9 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 GAP91311.1 - 6.9 5.7 22.3 0.53 9.3 3.9 2.5 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 GAP91311.1 - 6.9 6.7 8.9 17 5.5 1.0 2.6 2 1 2 4 4 3 0 Protein of unknown function (DUF1664) YlqD PF11068.8 GAP91311.1 - 7.5 6.9 16.3 0.36 11.2 4.1 2.9 3 0 0 3 3 3 0 YlqD protein Prefoldin_2 PF01920.20 GAP91311.1 - 7.7 6.5 18.3 11 6.1 4.5 3.4 2 1 1 3 3 2 0 Prefoldin subunit Syntaxin-6_N PF09177.11 GAP91311.1 - 7.8 7.1 13.7 3.1e+02 2.0 0.3 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TEX13 PF15186.6 GAP91311.1 - 8.2 6.1 15.3 0.28 10.9 5.3 2.8 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family CENP-Q PF13094.6 GAP91311.1 - 9.1 6.4 29.9 0.98 9.6 14.9 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Jnk-SapK_ap_N PF09744.9 GAP91311.1 - 10 6.4 26.2 5.1 7.3 7.9 3.0 2 1 0 3 3 3 0 JNK_SAPK-associated protein-1 Abhydrolase_1 PF00561.20 GAP91314.1 - 3.2e-17 63.0 0.0 6.3e-17 62.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP91314.1 - 1.4e-15 58.5 0.1 1.7e-15 58.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP91314.1 - 3.4e-13 49.4 0.0 1.4e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 GAP91314.1 - 0.00038 20.1 0.0 0.0008 19.1 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.14 GAP91315.1 - 2.2e-53 181.4 0.0 3.1e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_3 PF07859.13 GAP91316.1 - 8e-39 133.7 0.1 1.4e-38 132.9 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP91316.1 - 0.00017 22.2 11.3 0.00034 21.3 11.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP91316.1 - 0.11 11.7 0.0 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 COesterase PF00135.28 GAP91316.1 - 0.19 10.6 0.6 0.26 10.1 0.0 1.4 2 0 0 2 2 2 0 Carboxylesterase family DLH PF01738.18 GAP91316.1 - 0.21 11.1 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Semialdhyde_dhC PF02774.18 GAP91317.1 - 2.4e-39 135.3 0.0 3.1e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 GAP91317.1 - 2.2e-29 102.4 0.0 9.4e-29 100.3 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 GAP91317.1 - 0.02 15.6 0.0 0.05 14.3 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 GAP91317.1 - 0.021 14.9 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 GAP91317.1 - 0.065 13.5 0.1 0.18 12.1 0.0 1.9 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAT PF04768.13 GAP91318.1 - 4.6e-50 169.6 0.5 9.4e-50 168.6 0.2 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 GAP91318.1 - 2.1e-31 109.4 0.0 4.1e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Synaptobrevin PF00957.21 GAP91319.1 - 3.3e-33 113.3 1.6 3.8e-33 113.1 1.6 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 GAP91319.1 - 0.052 14.2 0.1 0.15 12.7 0.1 1.7 1 1 0 1 1 1 0 AT-hook-containing transcription factor MCU PF04678.13 GAP91319.1 - 0.076 13.1 0.1 0.094 12.8 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter HET PF06985.11 GAP91320.1 - 1.6e-26 93.4 0.0 4.5e-26 92.0 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ldh_1_N PF00056.23 GAP91321.1 - 2.6e-31 108.6 0.0 3.9e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 GAP91321.1 - 4.4e-17 62.5 0.0 8.2e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 GAP91321.1 - 0.011 16.3 0.1 0.083 13.5 0.1 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 GAP91321.1 - 0.015 15.6 0.3 0.14 12.4 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 GAP91321.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 GAP91321.1 - 0.077 12.6 0.4 0.55 9.8 0.4 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain WXG100 PF06013.12 GAP91322.1 - 0.14 12.4 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG SH3_6 PF12913.7 GAP91323.1 - 0.0046 16.5 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain (SH3b1 type) Glyco_hydro_76 PF03663.14 GAP91324.1 - 1.8e-153 511.4 21.5 2.1e-153 511.2 21.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TPPK_C PF12555.8 GAP91324.1 - 3.9 7.6 7.8 4.9 7.3 0.1 3.5 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal SKG6 PF08693.10 GAP91325.1 - 0.28 10.6 4.7 0.42 10.1 4.7 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain tRNA-synt_His PF13393.6 GAP91326.1 - 6.5e-40 137.3 0.0 8.1e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 GAP91326.1 - 6.7e-13 48.6 0.0 2.3e-12 46.9 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAP91326.1 - 1.5e-05 25.0 0.0 2.7e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 GAP91326.1 - 0.0045 16.1 0.0 0.035 13.2 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 GAP91326.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF4473 PF14747.6 GAP91326.1 - 0.12 12.9 1.1 0.38 11.3 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Peptidase_C6 PF00851.18 GAP91326.1 - 0.16 10.8 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 Helper component proteinase POP1 PF06978.11 GAP91327.1 - 3.9e-69 232.7 12.6 6.2e-69 232.1 12.6 1.3 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 GAP91327.1 - 4.3e-32 110.3 0.1 1.6e-31 108.5 0.1 2.0 1 0 0 1 1 1 1 POPLD (NUC188) domain NT-C2 PF10358.9 GAP91328.1 - 3.7e-26 91.6 0.1 8.8e-22 77.4 0.0 2.2 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins HSP70 PF00012.20 GAP91329.1 - 8.8e-78 262.0 1.2 1.4e-77 261.3 1.2 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAP91329.1 - 4.9e-07 28.9 0.1 8.7e-07 28.1 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein DUF3221 PF11518.8 GAP91329.1 - 0.017 15.4 1.3 0.042 14.2 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) Rrp40_N PF18311.1 GAP91330.1 - 2.6e-19 68.9 1.2 5.2e-19 67.9 0.5 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 GAP91330.1 - 1.7e-15 57.1 0.0 3.3e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 KH domain Peroxidase_2 PF01328.17 GAP91331.1 - 2.9e-39 135.5 0.0 3.5e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 2OG-FeII_Oxy_2 PF13532.6 GAP91332.1 - 5.8e-21 75.6 0.0 1e-20 74.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CorA PF01544.18 GAP91333.1 - 1.8e-08 34.1 3.2 3.5e-08 33.1 2.7 1.6 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein CCDC92 PF14916.6 GAP91333.1 - 0.041 13.7 1.0 0.082 12.7 1.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Ntox14 PF15522.6 GAP91333.1 - 0.18 11.2 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Novel toxin 14 SKG6 PF08693.10 GAP91333.1 - 0.29 10.6 1.9 3.5 7.1 0.7 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain FAD_binding_3 PF01494.19 GAP91334.1 - 7.9e-65 219.4 0.0 1.1e-64 218.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 GAP91334.1 - 3e-16 59.3 61.5 1.5e-11 43.8 37.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.6 GAP91334.1 - 4.6e-06 26.1 0.7 0.023 14.0 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP91334.1 - 1.7e-05 23.8 0.3 0.00072 18.4 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAP91334.1 - 0.00029 20.2 0.0 0.011 15.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 GAP91334.1 - 0.00037 20.0 0.0 0.00051 19.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAP91334.1 - 0.00062 18.9 1.0 0.0061 15.7 0.5 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 GAP91334.1 - 0.0018 18.5 0.1 0.0047 17.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP91334.1 - 0.0023 17.6 0.5 0.0079 15.8 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP91334.1 - 0.0025 16.9 0.3 0.004 16.3 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 GAP91334.1 - 0.016 15.2 0.6 3.4 7.6 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 GAP91334.1 - 0.028 15.0 0.0 0.24 12.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP91334.1 - 0.073 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DIT1_PvcA PF05141.12 GAP91335.1 - 7.2e-94 314.3 0.0 9e-94 314.0 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 GAP91335.1 - 5.6e-24 85.4 0.0 9.3e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WW_1 PF18507.1 GAP91335.1 - 0.02 14.6 0.5 0.039 13.6 0.5 1.4 1 0 0 1 1 1 0 WW domain Glyco_hydro_43 PF04616.14 GAP91336.1 - 7.7e-34 117.3 3.4 1.1e-33 116.8 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 GAP91336.1 - 3.6e-25 88.9 0.0 5.5e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain CW_binding_1 PF01473.20 GAP91336.1 - 6.5 7.3 11.6 12 6.5 1.8 4.1 3 0 0 3 3 3 0 Putative cell wall binding repeat p450 PF00067.22 GAP91337.1 - 2.8e-34 118.7 0.0 1.1e-25 90.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Tannase PF07519.11 GAP91338.1 - 2.2e-67 228.0 1.4 2.5e-51 175.1 0.8 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 GAP91338.1 - 0.031 13.7 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAP91338.1 - 0.1 12.2 0.6 0.19 11.4 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP91338.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 GAP91339.1 - 4e-88 296.5 0.0 5.5e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 GAP91339.1 - 7.5e-11 42.3 0.9 8.8e-10 38.8 0.2 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP91339.1 - 0.0061 16.1 0.3 0.011 15.2 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM-like PF14683.6 GAP91340.1 - 1.3e-24 86.9 0.0 4.8e-12 46.1 0.0 2.7 2 1 1 3 3 3 2 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 GAP91340.1 - 3.2e-09 36.4 0.0 9.3e-09 35.0 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 GAP91340.1 - 3.6e-06 27.2 0.4 7.3e-06 26.2 0.4 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.9 GAP91340.1 - 0.016 15.6 0.1 0.036 14.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) DUF4619 PF15398.6 GAP91340.1 - 0.24 10.9 0.3 0.46 10.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) DHHC PF01529.20 GAP91341.1 - 4.7e-37 127.1 4.5 9.1e-37 126.2 4.5 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.17 GAP91341.1 - 0.033 13.9 0.3 0.033 13.9 0.3 1.8 2 0 0 2 2 2 0 Yip1 domain HAD PF12710.7 GAP91343.1 - 2.5e-21 77.0 0.1 3.5e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP91343.1 - 5e-18 66.1 0.4 7.1e-18 65.7 0.4 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAP91343.1 - 1.5e-08 34.8 0.5 1.6e-07 31.3 0.1 2.3 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAP91343.1 - 0.00013 22.1 0.2 0.0029 17.7 0.2 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 GAP91343.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Put_Phosphatase PF06888.12 GAP91343.1 - 0.035 13.5 0.1 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase PAPS_reduct PF01507.19 GAP91344.1 - 1.1e-38 133.0 0.0 2.1e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family FAM199X PF15814.5 GAP91344.1 - 2.9 6.9 7.0 6.5 5.7 0.0 2.6 2 1 0 3 3 3 0 Protein family FAM199X Spt20 PF12090.8 GAP91344.1 - 4.6 6.8 14.9 8.2 6.0 14.9 1.3 1 0 0 1 1 1 0 Spt20 family Nop14 PF04147.12 GAP91345.1 - 0.045 12.0 2.4 0.067 11.4 2.4 1.2 1 0 0 1 1 1 0 Nop14-like family G5 PF07501.12 GAP91345.1 - 0.085 13.3 0.1 0.25 11.8 0.1 1.7 1 0 0 1 1 1 0 G5 domain BUD22 PF09073.10 GAP91345.1 - 0.25 10.7 7.2 0.012 15.0 2.0 1.4 2 0 0 2 2 2 0 BUD22 Complex1_LYR PF05347.15 GAP91346.1 - 6.4e-20 71.0 2.0 6.4e-20 71.0 2.0 2.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 GAP91346.1 - 1.7e-06 28.7 0.6 1.7e-06 28.7 0.6 3.1 3 1 0 3 3 3 1 Complex1_LYR-like zf-C6H2 PF15801.5 GAP91346.1 - 5.5e-06 26.6 14.8 0.0016 18.7 5.3 3.0 3 0 0 3 3 3 2 zf-MYND-like zinc finger, mRNA-binding Complex1_LYR_1 PF13232.6 GAP91346.1 - 0.24 12.0 0.2 0.24 12.0 0.2 2.8 3 1 1 4 4 4 0 Complex1_LYR-like DUF2203 PF09969.9 GAP91346.1 - 1.2 9.9 4.5 13 6.6 0.3 3.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) zf-MYND PF01753.18 GAP91346.1 - 6.7 6.9 16.2 0.2 11.8 3.4 3.3 3 0 0 3 3 3 0 MYND finger MAGE PF01454.19 GAP91347.1 - 9e-66 221.6 0.0 1.3e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 MAGE family SLS PF14611.6 GAP91348.1 - 1.6e-37 129.5 6.0 4.5e-37 128.0 0.9 2.4 2 0 0 2 2 2 2 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.27 GAP91349.1 - 2.6e-54 183.8 0.1 3.7e-54 183.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAP91349.1 - 9.5e-42 141.8 0.0 2.1e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAP91349.1 - 1.3e-13 51.1 0.6 1.3e-13 51.1 0.6 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAP91349.1 - 0.00089 19.3 0.1 0.019 15.0 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 GAP91349.1 - 0.18 11.7 1.9 0.2 11.5 0.4 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 EOS1 PF12326.8 GAP91350.1 - 2.4e-14 53.7 8.8 2.4e-14 53.7 8.8 2.4 2 1 1 3 3 3 1 N-glycosylation protein DUF2070 PF09843.9 GAP91350.1 - 0.041 12.2 7.0 0.049 11.9 7.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NADH_dehy_S2_C PF06444.11 GAP91350.1 - 0.095 13.2 3.4 0.41 11.2 0.3 2.5 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus MFS_1 PF07690.16 GAP91351.1 - 8.4e-38 130.2 34.1 1.3e-30 106.6 13.3 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP91351.1 - 8.3e-17 61.2 3.6 8.3e-17 61.2 3.6 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 GAP91351.1 - 0.00033 19.2 5.8 0.00033 19.2 5.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GTA_holin_3TM PF11351.8 GAP91351.1 - 0.82 10.2 0.0 0.82 10.2 0.0 2.5 3 0 0 3 3 3 0 Holin of 3TMs, for gene-transfer release ELP6 PF09807.9 GAP91352.1 - 1.3e-11 44.4 0.0 8.7e-11 41.7 0.0 1.9 2 0 0 2 2 2 1 Elongation complex protein 6 Autophagy_N PF03986.13 GAP91353.1 - 4.2e-45 153.1 0.0 8.1e-45 152.1 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 GAP91353.1 - 1.1e-16 61.1 0.1 2e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 GAP91353.1 - 5.1e-16 57.9 0.6 9.7e-16 57.0 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Xan_ur_permease PF00860.20 GAP91354.1 - 2.8e-26 92.1 29.8 1.4e-25 89.8 27.3 2.6 2 1 0 2 2 2 1 Permease family DUF3481 PF11980.8 GAP91354.1 - 1.6 8.5 3.8 13 5.6 0.4 2.5 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein MFS_MOT1 PF16983.5 GAP91354.1 - 2.3 8.6 24.4 0.036 14.5 3.6 3.6 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily Ldr_toxin PF13940.6 GAP91354.1 - 5.1 7.3 6.1 23 5.1 0.4 3.2 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system rhaM PF05336.13 GAP91355.1 - 9.6e-36 122.1 0.0 9.6e-36 122.1 0.0 1.9 2 0 0 2 2 2 1 L-rhamnose mutarotase DUF2722 PF10846.8 GAP91355.1 - 0.0095 14.9 5.6 0.0098 14.9 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 GAP91355.1 - 0.52 9.9 14.7 0.66 9.5 14.7 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 GAP91355.1 - 0.77 9.7 10.8 0.91 9.5 10.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2367 PF10164.9 GAP91355.1 - 2.3 8.8 3.7 3.7 8.1 3.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Med3 PF11593.8 GAP91355.1 - 5.8 6.0 11.5 7.1 5.7 11.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UPF0016 PF01169.19 GAP91356.1 - 1.1e-40 137.8 24.8 3.6e-20 72.1 7.4 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Myb_DNA-bind_4 PF13837.6 GAP91357.1 - 0.019 15.3 0.1 0.053 13.9 0.1 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MBA1 PF07961.11 GAP91358.1 - 1.7e-08 33.8 0.0 2.2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 GAP91358.1 - 1.2e-05 25.5 0.1 2.9e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 Tim44-like domain F-box-like PF12937.7 GAP91359.1 - 0.0013 18.5 0.4 0.0042 17.0 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP91359.1 - 0.022 14.6 1.3 0.14 12.1 0.4 2.4 2 0 0 2 2 2 0 F-box domain SSF PF00474.17 GAP91360.1 - 5.4e-07 28.8 30.0 1.9e-06 27.0 29.9 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family FMN_dh PF01070.18 GAP91361.1 - 2.2e-85 286.7 4.3 5.7e-47 160.4 1.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 GAP91361.1 - 0.00017 20.7 0.2 0.00027 20.1 0.2 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 GAP91361.1 - 0.00028 20.1 0.1 0.00044 19.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 GAP91361.1 - 0.036 13.5 0.3 0.072 12.5 0.3 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Peptidase_M26_N PF05342.14 GAP91361.1 - 0.062 12.7 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region DHO_dh PF01180.21 GAP91361.1 - 0.1 11.8 0.4 1.4 8.1 0.1 2.3 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase HAP1_N PF04849.13 GAP91362.1 - 0.06 12.5 0.2 0.1 11.7 0.2 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region CorA PF01544.18 GAP91362.1 - 0.076 12.3 6.7 0.15 11.3 6.7 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein WAP PF00095.21 GAP91363.1 - 0.088 13.2 10.4 1.1 9.7 2.2 2.5 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Sdh_cyt PF01127.22 GAP91364.1 - 3.6e-16 59.3 3.7 4.9e-16 58.9 3.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TAF6_C PF07571.13 GAP91365.1 - 9.3e-26 90.0 0.0 2.3e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 GAP91365.1 - 1.3e-21 76.5 0.1 3.1e-21 75.3 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 GAP91365.1 - 0.055 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 GAP91365.1 - 0.17 12.2 0.1 0.27 11.6 0.1 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 GATase_6 PF13522.6 GAP91366.1 - 3.4e-14 53.2 0.0 8.6e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 GAP91366.1 - 5.3e-12 45.7 0.0 9.7e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 GAP91366.1 - 1.9e-05 24.2 0.1 4.3e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 GAP91366.1 - 0.00041 19.4 0.0 0.00067 18.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HsbA PF12296.8 GAP91369.1 - 8.4e-19 68.2 12.7 1.6e-18 67.3 12.7 1.5 1 0 0 1 1 1 1 Hydrophobic surface binding protein A RmuC PF02646.16 GAP91369.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 RmuC family GST_N_3 PF13417.6 GAP91370.1 - 9.1e-19 67.7 0.0 2.2e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAP91370.1 - 2.2e-16 59.9 0.0 5.5e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP91370.1 - 1.3e-09 37.9 4.4 4.3e-09 36.3 1.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 GAP91370.1 - 8.5e-09 35.6 0.2 0.00015 22.0 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP91370.1 - 0.032 14.4 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAP91370.1 - 0.035 14.7 0.0 0.072 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAP91370.1 - 0.062 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CorA PF01544.18 GAP91371.1 - 9.3e-09 35.0 1.0 9.3e-09 35.0 1.0 2.1 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 GAP91371.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 GAP91371.1 - 0.0047 16.2 0.0 0.0097 15.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAP91371.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Palm_thioest PF02089.15 GAP91371.1 - 0.06 13.2 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Palmitoyl protein thioesterase DUF3716 PF12511.8 GAP91372.1 - 1.3e-14 53.9 3.5 2e-14 53.4 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) p450 PF00067.22 GAP91373.1 - 1.7e-34 119.4 0.0 2.4e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L27 PF01016.19 GAP91374.1 - 9.5e-27 92.8 0.1 1.9e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein DUF3138 PF11336.8 GAP91374.1 - 0.25 9.9 0.9 0.37 9.4 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) IPP-2 PF04979.14 GAP91375.1 - 2.8e-23 83.1 11.7 2.8e-23 83.1 11.7 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Dicty_REP PF05086.12 GAP91375.1 - 4 5.3 7.5 5.2 4.9 7.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UvdE PF03851.14 GAP91376.1 - 4.9e-116 386.8 0.0 6.5e-116 386.4 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE SET PF00856.28 GAP91377.1 - 9.8e-18 65.1 0.0 2.2e-17 64.0 0.0 1.6 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 GAP91377.1 - 3.4e-05 24.6 0.6 0.00013 22.7 0.0 2.1 2 1 1 3 3 3 1 Rubisco LSMT substrate-binding FAD_binding_1 PF00667.20 GAP91379.1 - 2.5e-40 138.4 0.0 3.4e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 GAP91379.1 - 2.8e-29 102.2 0.0 4.8e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 GAP91379.1 - 1.1e-19 71.1 0.0 1e-18 67.9 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain p450 PF00067.22 GAP91380.1 - 1.5e-64 218.5 0.0 1.9e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Choline_sulf_C PF12411.8 GAP91380.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal Fungal_trans_2 PF11951.8 GAP91381.1 - 7.8e-11 41.4 0.0 1.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP91381.1 - 2.3e-05 24.4 11.4 4.4e-05 23.5 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 GAP91382.1 - 2.2e-98 330.1 29.0 2.6e-98 329.9 29.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP91382.1 - 1e-27 97.0 33.2 1e-27 97.0 33.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 GAP91382.1 - 0.11 13.1 7.9 1.3 9.6 2.2 3.6 3 0 0 3 3 3 0 Phage holin family 2 Colicin_im PF03857.13 GAP91382.1 - 1.1 9.2 5.2 0.3 11.1 0.5 2.1 2 0 0 2 2 2 0 Colicin immunity protein GFO_IDH_MocA PF01408.22 GAP91383.1 - 1.8e-24 86.8 0.2 2.8e-24 86.2 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAP91383.1 - 5.9e-06 26.3 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 GAP91383.1 - 0.0056 17.3 0.1 0.0094 16.6 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAP91383.1 - 0.057 13.6 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TRP PF06011.12 GAP91384.1 - 5.4e-14 51.7 24.9 0.00021 20.2 12.7 4.0 4 0 0 4 4 4 4 Transient receptor potential (TRP) ion channel Miga PF10265.9 GAP91384.1 - 1.7 7.5 4.0 12 4.7 2.5 2.1 2 0 0 2 2 2 0 Mitoguardin Ank_4 PF13637.6 GAP91387.1 - 3.4e-16 59.4 5.8 5.4e-09 36.4 1.3 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP91387.1 - 1.6e-14 54.2 1.6 6e-10 39.6 0.1 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 GAP91387.1 - 3.3e-13 49.4 5.7 2.1e-08 34.3 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 GAP91387.1 - 6.4e-13 48.6 0.9 8.1e-10 38.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP91387.1 - 1e-10 40.9 1.9 3.3e-06 27.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat TP6A_N PF04406.14 GAP91388.1 - 1.5e-16 60.1 0.0 8.7e-16 57.7 0.0 2.2 1 1 0 1 1 1 1 Type IIB DNA topoisomerase SQHop_cyclase_C PF13243.6 GAP91389.1 - 5.9e-47 160.3 3.4 2.3e-45 155.1 2.0 2.7 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 GAP91389.1 - 8.1e-38 130.2 4.5 3.9e-33 114.8 0.5 3.2 3 1 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 GAP91389.1 - 2.3e-26 91.2 1.9 3.5e-09 36.3 0.1 3.8 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 GAP91389.1 - 0.00016 20.9 0.2 0.0004 19.5 0.2 1.7 1 0 0 1 1 1 1 A-macroglobulin TED domain Pec_lyase PF09492.10 GAP91389.1 - 0.00052 19.4 0.6 0.21 10.9 0.2 3.8 2 1 1 4 4 4 1 Pectic acid lyase SGS PF05002.15 GAP91390.1 - 2e-30 104.7 6.1 4.5e-30 103.6 6.1 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.16 GAP91390.1 - 1e-09 39.3 0.0 1.8e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 GAP91390.1 - 0.0094 16.0 3.8 11 6.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAP91390.1 - 0.22 12.2 5.6 2.5 8.8 2.2 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat p450 PF00067.22 GAP91391.1 - 1.6e-57 195.3 0.0 8.5e-57 192.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.22 GAP91393.1 - 1.3e-28 100.1 20.5 3.3e-28 98.8 20.5 1.6 1 1 0 1 1 1 1 Subtilase family SRP54 PF00448.22 GAP91394.1 - 7.1e-77 257.5 1.1 1.2e-76 256.8 1.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 GAP91394.1 - 1.1e-29 103.0 1.0 1.1e-29 103.0 1.0 3.5 2 1 2 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 GAP91394.1 - 7e-18 64.6 0.1 2.1e-17 63.1 0.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 GAP91394.1 - 8.7e-07 28.7 0.7 4.6e-06 26.3 0.7 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 GAP91394.1 - 8.9e-07 29.2 0.0 2.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAP91394.1 - 8.7e-06 26.2 0.4 3e-05 24.5 0.1 2.1 2 0 0 2 2 1 1 AAA domain MeaB PF03308.16 GAP91394.1 - 0.00031 19.8 0.6 0.0021 17.1 0.6 2.2 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 GAP91394.1 - 0.00037 20.9 0.0 0.00069 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 GAP91394.1 - 0.001 18.4 0.0 0.0022 17.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 GAP91394.1 - 0.0015 19.1 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 GAP91394.1 - 0.0016 18.5 0.0 0.0047 17.0 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 GAP91394.1 - 0.0017 18.4 0.2 0.054 13.6 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase APS_kinase PF01583.20 GAP91394.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 GAP91394.1 - 0.0026 17.5 0.0 0.0026 17.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 GAP91394.1 - 0.0037 17.0 0.1 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase ATP_bind_1 PF03029.17 GAP91394.1 - 0.0047 16.7 0.6 0.05 13.4 0.1 2.6 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 GAP91394.1 - 0.0083 16.4 0.0 0.024 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 GAP91394.1 - 0.01 15.9 0.3 0.052 13.6 0.3 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 GAP91394.1 - 0.012 15.8 0.2 0.024 14.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAP91394.1 - 0.014 15.7 0.0 0.041 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 GAP91394.1 - 0.018 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.9 GAP91394.1 - 0.034 13.1 0.0 0.086 11.7 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SRPRB PF09439.10 GAP91394.1 - 0.034 13.6 1.0 2.8 7.3 0.8 2.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit 6PF2K PF01591.18 GAP91394.1 - 0.046 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.21 GAP91394.1 - 0.076 12.5 0.1 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.29 GAP91394.1 - 0.095 13.1 0.3 0.38 11.2 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 GAP91394.1 - 0.11 13.0 0.4 0.37 11.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 GAP91394.1 - 0.19 11.6 0.9 1.5 8.7 0.0 2.2 1 1 1 2 2 2 0 NTPase DUF963 PF06131.11 GAP91395.1 - 0.23 10.9 0.1 0.23 10.9 0.1 6.3 3 2 2 6 6 6 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) PAP2 PF01569.21 GAP91396.1 - 4.1e-26 91.4 1.2 4.1e-26 91.4 1.2 2.2 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 GAP91396.1 - 0.53 9.9 11.6 1.7 8.3 8.1 2.9 2 1 0 2 2 2 0 PAP2 superfamily TNFR_16_TM PF18422.1 GAP91396.1 - 0.99 9.4 6.8 1.1 9.3 0.8 2.7 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Glyco_hydro_43 PF04616.14 GAP91397.1 - 5.6e-06 25.9 0.0 0.00071 19.0 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 GAP91397.1 - 0.00061 19.4 0.0 0.0013 18.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain HET PF06985.11 GAP91398.1 - 6.7e-27 94.6 0.0 1.7e-26 93.3 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.17 GAP91400.1 - 5.8e-06 26.0 6.0 0.00075 19.4 2.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAP91400.1 - 0.00086 19.9 14.0 0.06 14.2 2.1 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAP91400.1 - 0.0029 18.2 17.5 0.1 13.3 1.9 2.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 GAP91400.1 - 0.0034 17.6 5.9 0.44 10.9 1.3 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP91400.1 - 0.05 13.8 0.2 1.4 9.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAP91400.1 - 0.06 13.2 4.5 0.14 12.0 0.9 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 GAP91400.1 - 0.099 12.7 3.6 6.5 7.0 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 GAP91400.1 - 0.1 13.1 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 GAP91400.1 - 0.37 10.7 8.0 6.9 6.7 2.8 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Clr5 PF14420.6 GAP91401.1 - 7.1e-17 61.4 2.1 1.3e-16 60.5 1.5 1.8 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.6 GAP91401.1 - 1.1e-05 25.6 1.4 8.3e-05 22.8 0.5 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Peptidase_M43 PF05572.13 GAP91404.1 - 1.6e-16 60.6 0.1 2.4e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 GAP91404.1 - 4.2e-07 30.3 1.1 1e-06 29.0 1.0 1.6 1 1 1 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 GAP91404.1 - 1.8e-06 28.5 0.1 4.2e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like CVNH PF08881.10 GAP91405.1 - 4.3e-21 75.5 6.4 1e-13 51.8 0.8 1.7 1 1 1 2 2 2 2 CVNH domain Glyco_hyd_65N_2 PF14498.6 GAP91406.1 - 2.2e-49 168.5 0.0 3.3e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 GAP91406.1 - 0.042 12.7 0.2 0.072 11.9 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain FTA2 PF13095.6 GAP91407.1 - 3.3e-38 131.5 0.0 4.5e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 UDPGT PF00201.18 GAP91408.1 - 0.00068 18.6 0.0 0.0009 18.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PBP PF01161.20 GAP91409.1 - 1.1e-08 35.5 0.0 2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.22 GAP91410.1 - 1.9e-42 145.1 0.0 2.5e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family bZIP_1 PF00170.21 GAP91411.1 - 6.7e-11 42.1 2.8 1e-10 41.6 2.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 GAP91411.1 - 3e-06 27.2 1.0 5.1e-06 26.5 1.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 GAP91411.1 - 0.00042 20.8 3.7 0.00079 19.9 3.7 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Rep_fac-A_3 PF08661.11 GAP91412.1 - 2e-21 76.3 0.1 3.5e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Replication factor A protein 3 GATA PF00320.27 GAP91413.1 - 0.00052 19.6 5.8 0.053 13.1 2.0 2.6 2 0 0 2 2 2 2 GATA zinc finger ECH_2 PF16113.5 GAP91414.1 - 5.8e-122 407.3 0.0 7.6e-122 407.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 GAP91414.1 - 7.3e-27 94.3 0.0 1.5e-25 90.0 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Ribosomal_L18 PF17135.4 GAP91414.1 - 0.11 11.9 0.0 7 6.0 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein 60S L18 and 50S L18e LSM PF01423.22 GAP91415.1 - 1.6e-17 62.9 0.1 2.3e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 GAP91415.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Dak1 PF02733.17 GAP91416.1 - 1.2e-107 359.4 7.3 1.7e-107 358.9 7.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 GAP91416.1 - 1.6e-44 151.8 0.2 1.6e-44 151.8 0.2 1.7 2 0 0 2 2 2 1 DAK2 domain IF-2B PF01008.17 GAP91417.1 - 6.1e-47 160.2 0.0 1.8e-46 158.6 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family PAN_4 PF14295.6 GAP91419.1 - 6.9e-06 25.9 1.8 1.2e-05 25.1 1.8 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 GAP91419.1 - 5e-05 23.2 0.7 0.00011 22.1 0.7 1.5 1 0 0 1 1 1 1 PAN domain PUCC PF03209.15 GAP91419.1 - 0.042 12.9 0.1 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 PUCC protein COMPASS-Shg1 PF05205.12 GAP91420.1 - 1.6e-25 89.8 0.3 1.6e-25 89.8 0.3 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 SPRY PF00622.28 GAP91421.1 - 7.1e-19 68.1 0.0 1.7e-18 66.9 0.0 1.6 2 0 0 2 2 2 1 SPRY domain Ecl1 PF12855.7 GAP91421.1 - 5.3 8.2 10.6 11 7.2 10.6 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Rtt102p PF09510.10 GAP91423.1 - 0.02 15.1 0.6 0.024 14.8 0.6 1.2 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein Acetyltransf_10 PF13673.7 GAP91425.1 - 5.3e-06 26.4 0.0 8.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP91425.1 - 2e-05 24.9 0.1 0.00012 22.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP91425.1 - 0.00032 20.9 0.1 0.0019 18.4 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 GAP91425.1 - 0.0005 20.0 0.0 0.00099 19.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein ABC2_membrane PF01061.24 GAP91426.1 - 1.8e-78 262.7 49.0 2.8e-46 157.6 23.0 3.9 3 1 1 4 4 4 3 ABC-2 type transporter ABC_tran PF00005.27 GAP91426.1 - 1.1e-28 100.5 0.0 5.2e-15 56.2 0.0 2.9 2 1 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 GAP91426.1 - 7.2e-15 54.7 11.4 1.3e-06 28.2 0.0 4.9 3 1 1 4 4 4 3 CDR ABC transporter AAA_16 PF13191.6 GAP91426.1 - 1.1e-07 32.5 0.4 6.8e-05 23.3 0.2 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 GAP91426.1 - 3.1e-07 30.2 0.0 5.1e-05 22.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 GAP91426.1 - 2.1e-06 27.4 0.9 0.0018 18.0 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_trans_N PF14510.6 GAP91426.1 - 4.8e-06 27.1 0.4 0.0058 17.2 0.1 2.9 1 1 1 2 2 2 2 ABC-transporter N-terminal AAA_18 PF13238.6 GAP91426.1 - 8.9e-06 26.3 0.0 0.0054 17.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 GAP91426.1 - 1.1e-05 25.4 0.1 0.0014 18.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 GAP91426.1 - 4.3e-05 23.7 0.0 0.062 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 GAP91426.1 - 5.3e-05 23.2 0.0 0.037 13.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 GAP91426.1 - 0.00025 21.0 0.0 0.078 12.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 GAP91426.1 - 0.0018 18.7 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 GAP91426.1 - 0.0042 17.4 0.2 0.66 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 GAP91426.1 - 0.0042 17.5 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAP91426.1 - 0.0044 16.8 0.1 0.72 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 GAP91426.1 - 0.0046 17.5 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 GAP91426.1 - 0.0052 16.4 1.0 0.051 13.2 0.2 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 GAP91426.1 - 0.013 15.7 1.5 0.63 10.3 0.1 3.3 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 GAP91426.1 - 0.017 14.8 0.1 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 GAP91426.1 - 0.029 14.4 0.0 2.6 8.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 GAP91426.1 - 0.043 13.2 0.0 18 4.6 0.0 3.6 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 GAP91426.1 - 0.14 11.9 1.4 13 5.4 0.3 2.3 2 0 0 2 2 2 0 AAA domain Glyco_hydro_30 PF02055.16 GAP91427.1 - 5.9e-32 111.0 0.8 8.1e-32 110.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 GAP91427.1 - 3.3e-07 30.4 0.4 7.4e-07 29.3 0.4 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 GAP91427.1 - 1.4e-05 24.9 0.0 0.00012 21.8 0.0 2.0 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 GAP91427.1 - 0.00012 21.5 1.5 0.00022 20.6 1.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Bac_surface_Ag PF01103.23 GAP91430.1 - 3.2e-38 132.0 0.1 4.7e-38 131.5 0.1 1.3 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.26 GAP91431.1 - 1.1e-20 73.8 0.0 1.5e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAP91431.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B E1-E2_ATPase PF00122.20 GAP91433.1 - 7e-36 123.4 17.1 3.3e-29 101.7 0.1 4.1 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 GAP91433.1 - 9.2e-28 97.2 3.9 9.2e-28 97.2 3.9 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 GAP91433.1 - 3.4e-18 66.7 0.4 3.6e-17 63.4 0.4 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAP91433.1 - 2e-15 56.2 0.1 6.1e-15 54.7 0.1 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 GAP91433.1 - 2.7e-14 53.0 0.0 5.2e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAP91433.1 - 2.8e-05 24.0 3.1 3.8e-05 23.6 1.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Amidohydro_3 PF07969.11 GAP91434.1 - 6.2e-28 98.5 0.3 8.3e-28 98.1 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 GAP91434.1 - 0.024 14.0 0.1 0.045 13.1 0.0 1.5 2 0 0 2 2 2 0 Amidohydrolase family AATase PF07247.12 GAP91435.1 - 0.0015 17.1 0.0 0.0019 16.9 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 GAP91435.1 - 0.23 10.1 0.0 0.31 9.7 0.0 1.1 1 0 0 1 1 1 0 Condensation domain Chromo PF00385.24 GAP91437.1 - 4e-13 49.1 1.0 3.4e-06 26.9 0.3 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PBP1_TM PF14812.6 GAP91437.1 - 0.012 15.9 14.3 0.16 12.4 2.2 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Lir1 PF07207.11 GAP91437.1 - 0.023 15.0 0.1 0.047 13.9 0.1 1.4 1 0 0 1 1 1 0 Light regulated protein Lir1 FAM176 PF14851.6 GAP91437.1 - 0.71 9.5 10.8 1.2 8.8 6.2 2.3 2 0 0 2 2 2 0 FAM176 family PTPRCAP PF15713.5 GAP91437.1 - 0.77 10.0 19.8 0.89 9.8 16.6 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated SURF2 PF05477.11 GAP91437.1 - 0.89 9.2 8.6 0.21 11.3 4.6 1.8 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 GAP91437.1 - 1.3 7.1 11.6 0.082 11.1 6.7 1.4 2 0 0 2 2 2 0 Nop14-like family PPP4R2 PF09184.11 GAP91437.1 - 2 7.9 14.8 4 7.0 14.8 1.4 1 1 0 1 1 1 0 PPP4R2 DUF4746 PF15928.5 GAP91437.1 - 2.2 7.7 9.7 7.9 5.8 9.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Cwf_Cwc_15 PF04889.12 GAP91437.1 - 2.5 7.8 13.7 0.72 9.5 5.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pes-10 PF07149.11 GAP91437.1 - 4.4 6.3 8.4 6.4 5.7 8.4 1.2 1 0 0 1 1 1 0 Pes-10 TRAP_alpha PF03896.16 GAP91437.1 - 4.5 6.4 6.4 8.3 5.5 6.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cu-oxidase_2 PF07731.14 GAP91438.1 - 2.1e-40 137.6 3.5 5.7e-39 133.0 0.2 3.0 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 GAP91438.1 - 2.1e-30 105.9 0.1 9.8e-30 103.8 0.0 2.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAP91438.1 - 1.8e-24 86.1 9.4 2.6e-14 53.2 0.1 3.5 3 1 1 4 4 4 2 Multicopper oxidase Mad3_BUB1_II PF08171.11 GAP91439.1 - 0.13 12.4 0.0 3.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Mad3/BUB1 homology region 2 p450 PF00067.22 GAP91441.1 - 1.1e-54 185.9 0.0 1.5e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 GAP91442.1 - 1.4e-77 261.4 34.0 1.8e-77 261.0 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP91442.1 - 2e-15 56.4 30.0 4.5e-15 55.2 30.0 1.6 1 1 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 GAP91445.1 - 5.3e-68 229.6 0.0 4.3e-67 226.5 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP91445.1 - 7.4e-07 30.1 0.1 3.8e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 4HBT PF03061.22 GAP91446.1 - 1e-14 54.6 0.2 1.4e-14 54.1 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 GAP91446.1 - 0.0071 16.5 0.0 0.0099 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) AstE_AspA PF04952.14 GAP91447.1 - 0.41 9.7 1.5 0.72 8.9 1.5 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family GCR1_C PF12550.8 GAP91450.1 - 7.4e-23 80.7 1.6 1.2e-22 80.0 1.6 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TolA_bind_tri PF16331.5 GAP91450.1 - 0.037 14.1 2.6 0.073 13.2 2.6 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation MRP-S34 PF16053.5 GAP91452.1 - 0.069 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 Aminotran_1_2 PF00155.21 GAP91453.1 - 6e-39 134.2 0.0 8.1e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.9 GAP91454.1 - 5.6e-57 192.2 0.4 9.5e-57 191.5 0.4 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 GAP91454.1 - 1.7e-12 47.7 0.0 3.8e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_6 PF13174.6 GAP91454.1 - 0.65 10.8 3.1 4.3 8.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pox_MCEL PF03291.16 GAP91455.1 - 2.8e-68 230.5 0.0 2.2e-46 158.5 0.0 2.5 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 GAP91455.1 - 7.3e-10 39.4 0.1 0.00012 22.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 GAP91455.1 - 1.6e-07 32.0 0.0 0.015 16.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 GAP91455.1 - 1e-05 25.4 0.0 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP91455.1 - 3.1e-05 24.6 0.1 0.25 12.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 GAP91455.1 - 0.00038 20.3 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 GAP91455.1 - 0.0013 18.0 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Raftlin PF15250.6 GAP91455.1 - 0.056 12.2 1.1 0.084 11.6 0.0 1.7 2 0 0 2 2 2 0 Raftlin Phytase-like PF13449.6 GAP91457.1 - 1.4e-36 126.9 0.0 1.8e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase NHL PF01436.21 GAP91457.1 - 0.0099 15.9 0.1 0.048 13.7 0.1 2.2 2 0 0 2 2 2 1 NHL repeat Nrf1_activ_bdg PF10492.9 GAP91458.1 - 0.13 12.9 3.9 0.24 12.1 2.6 2.0 2 0 0 2 2 2 0 Nrf1 activator activation site binding domain DUF4196 PF13846.6 GAP91458.1 - 0.27 11.4 3.3 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) Macoilin PF09726.9 GAP91458.1 - 0.6 8.6 3.5 0.8 8.2 3.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF4578 PF15147.6 GAP91458.1 - 0.61 11.0 4.6 1.7 9.5 4.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) DPM3 PF08285.11 GAP91459.1 - 3.7e-37 126.4 0.2 4.1e-37 126.3 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3007 PF11460.8 GAP91459.1 - 0.012 15.8 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Zn_clus PF00172.18 GAP91460.1 - 1.4e-07 31.5 11.3 3e-07 30.5 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP91460.1 - 4.2e-07 29.3 0.0 8.9e-07 28.2 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF148 PF02520.17 GAP91460.1 - 0.059 13.5 0.3 0.15 12.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 FAD_binding_4 PF01565.23 GAP91461.1 - 4.9e-24 84.7 1.7 8.1e-24 83.9 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP91461.1 - 0.0074 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like HMG_box PF00505.19 GAP91462.1 - 6.7e-05 23.2 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 GAP91462.1 - 0.0071 16.9 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain Tim54 PF11711.8 GAP91462.1 - 0.031 13.1 5.8 0.049 12.4 5.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Lipase_GDSL PF00657.22 GAP91463.1 - 0.00023 21.2 0.0 0.00029 20.9 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase COX14 PF14880.6 GAP91464.1 - 1.2e-16 60.3 0.9 2.5e-16 59.3 0.1 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF3439 PF11921.8 GAP91464.1 - 0.41 10.6 7.7 0.9 9.5 7.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Nucleoporin_FG2 PF15967.5 GAP91464.1 - 0.67 8.4 15.5 0.074 11.6 5.5 2.1 2 0 0 2 2 2 0 Nucleoporin FG repeated region TSP9 PF11493.8 GAP91464.1 - 4.7 8.0 6.8 1.2 9.8 1.2 2.7 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 Ribosomal_L13e PF01294.18 GAP91466.1 - 2.4e-71 239.3 1.9 3.3e-71 238.9 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Arm PF00514.23 GAP91467.1 - 3.7e-05 23.6 2.9 0.22 11.6 0.0 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat KAP PF05804.12 GAP91467.1 - 0.0016 16.7 0.0 0.0066 14.6 0.0 1.7 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) TPR_10 PF13374.6 GAP91468.1 - 1.6e-75 247.1 31.4 3.5e-10 39.4 0.2 11.0 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 GAP91468.1 - 4.5e-60 199.9 42.8 6.3e-12 45.6 1.4 8.1 5 1 5 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 GAP91468.1 - 2.6e-32 108.3 4.2 0.15 12.3 0.0 11.3 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_14 PF13428.6 GAP91468.1 - 2.1e-26 90.3 23.3 0.18 12.7 0.1 11.5 10 1 2 12 12 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 GAP91468.1 - 4.4e-24 82.6 8.4 0.13 12.5 0.0 11.0 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 GAP91468.1 - 5.3e-24 84.5 39.6 3.8e-05 24.1 0.0 8.5 3 2 6 9 9 9 8 Tetratricopeptide repeat TPR_6 PF13174.6 GAP91468.1 - 6.9e-22 76.6 22.7 0.12 13.1 0.1 11.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 GAP91468.1 - 5.9e-21 73.4 2.6 1.8 8.6 0.0 10.8 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.6 GAP91468.1 - 6.2e-20 69.7 16.6 0.17 12.0 0.1 10.5 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_20 PF14561.6 GAP91468.1 - 7.4e-20 71.1 40.0 0.014 15.7 0.3 9.2 1 1 8 9 9 9 8 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP91468.1 - 1.3e-18 66.9 21.4 0.014 15.6 0.1 9.2 2 1 7 9 9 9 6 Anaphase-promoting complex, cyclosome, subunit 3 Patatin PF01734.22 GAP91468.1 - 1.5e-17 64.4 0.0 4.8e-17 62.8 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase TPR_16 PF13432.6 GAP91468.1 - 4.5e-16 59.2 18.5 0.11 13.2 1.7 9.4 7 1 1 8 8 8 4 Tetratricopeptide repeat PPR PF01535.20 GAP91468.1 - 6.9e-14 51.0 0.0 11 6.5 0.0 9.5 9 0 0 9 9 9 0 PPR repeat TPR_MalT PF17874.1 GAP91468.1 - 1.6e-12 47.4 38.2 0.0011 18.4 2.0 4.8 1 1 6 7 7 7 7 MalT-like TPR region TPR_4 PF07721.14 GAP91468.1 - 2.8e-10 39.8 51.9 0.25 12.1 1.1 10.4 11 0 0 11 11 9 4 Tetratricopeptide repeat NB-ARC PF00931.22 GAP91468.1 - 4.4e-10 39.2 0.0 9.6e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Vps39_1 PF10366.9 GAP91468.1 - 4.1e-07 30.3 17.3 9.3 6.6 0.4 8.1 1 1 7 8 8 8 0 Vacuolar sorting protein 39 domain 1 TPR_17 PF13431.6 GAP91468.1 - 2.7e-06 27.4 24.5 7.9 7.1 0.0 9.1 9 0 0 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 GAP91468.1 - 2e-05 24.1 18.1 31 4.4 0.1 9.2 10 0 0 10 10 10 0 Fis1 N-terminal tetratricopeptide repeat NACHT PF05729.12 GAP91468.1 - 7.3e-05 22.7 0.0 0.00021 21.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP91468.1 - 0.00014 22.3 1.7 0.00014 22.3 1.7 4.6 3 2 0 3 3 2 1 AAA ATPase domain ATG16 PF08614.11 GAP91468.1 - 0.0053 17.0 34.0 6 7.0 0.5 6.3 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) PPR_1 PF12854.7 GAP91468.1 - 0.017 14.8 16.4 26 4.6 0.1 8.5 9 0 0 9 9 9 0 PPR repeat DUF3301 PF11743.8 GAP91468.1 - 0.029 14.0 10.9 3.7 7.3 0.1 5.6 2 1 2 5 5 5 0 Protein of unknown function (DUF3301) AAA PF00004.29 GAP91468.1 - 0.14 12.5 0.0 0.61 10.5 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Stk19 PF10494.9 GAP91468.1 - 0.34 10.6 12.6 1.4 8.6 2.8 3.9 2 1 1 4 4 4 0 Serine-threonine protein kinase 19 Clathrin PF00637.20 GAP91468.1 - 0.69 9.8 12.0 9.1 6.2 1.1 5.6 2 2 2 6 6 6 0 Region in Clathrin and VPS HSA PF07529.13 GAP91468.1 - 1 9.7 6.8 31 5.0 0.1 4.9 3 2 2 5 5 4 0 HSA TPR_3 PF07720.12 GAP91468.1 - 2.9 8.0 36.7 9.6 6.3 0.4 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat Lipase_GDSL_2 PF13472.6 GAP91470.1 - 3e-21 76.6 2.2 3e-21 76.6 2.2 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP91470.1 - 1.9e-07 31.2 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DAHP_synth_1 PF00793.20 GAP91471.1 - 7.1e-103 343.2 0.1 8.9e-103 342.9 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family K_channel_TID PF07941.11 GAP91472.1 - 0.0042 17.5 14.5 0.0085 16.5 14.5 1.4 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain zf-P11 PF03854.14 GAP91472.1 - 0.21 11.3 4.5 0.33 10.6 4.5 1.3 1 0 0 1 1 1 0 P-11 zinc finger Ribosomal_L50 PF10501.9 GAP91473.1 - 3.6e-11 43.2 0.0 7.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S 4HBT PF03061.22 GAP91474.1 - 0.0034 17.7 0.4 0.15 12.5 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily MFS_1 PF07690.16 GAP91475.1 - 2.6e-36 125.3 54.1 5.9e-36 124.1 52.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP91475.1 - 2.3e-12 46.5 10.2 2.3e-12 46.5 10.2 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAP91475.1 - 4.1e-08 32.1 15.7 8.3e-08 31.1 15.7 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_6 PF07332.11 GAP91475.1 - 0.16 12.0 0.2 0.16 12.0 0.2 5.6 4 2 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III OATP PF03137.20 GAP91475.1 - 0.29 9.4 11.3 0.0071 14.7 2.2 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NmrA PF05368.13 GAP91476.1 - 1.3e-31 110.0 0.0 1.5e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP91476.1 - 1e-16 61.4 0.0 1.6e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP91476.1 - 7.8e-07 28.8 0.0 2e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sec3_C_2 PF15278.6 GAP91476.1 - 0.11 12.9 0.6 2.9 8.3 0.6 2.9 2 1 0 2 2 2 0 Sec3 exocyst complex subunit Semialdhyde_dh PF01118.24 GAP91476.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 GAP91476.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 GAP91477.1 - 9.2e-25 87.3 0.0 2e-24 86.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 GAP91478.1 - 5e-17 61.9 0.0 6.7e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DUF5343 PF17278.2 GAP91478.1 - 0.055 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5343) Methyltransf_2 PF00891.18 GAP91479.1 - 5e-19 68.4 0.0 8e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 GAP91479.1 - 0.018 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 GAP91479.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 GAP91480.1 - 8e-50 169.6 0.0 2.2e-49 168.2 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 GAP91480.1 - 1.3e-26 94.1 0.1 1.1e-25 91.1 0.1 2.2 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 GAP91480.1 - 2.7e-08 34.0 0.0 6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 GAP91480.1 - 0.00023 21.9 2.7 0.00045 20.9 2.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP91480.1 - 0.00026 20.7 0.1 0.00042 20.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold GH3 PF03321.13 GAP91480.1 - 0.062 12.2 0.0 0.3 9.9 0.0 1.9 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Hydrolase_4 PF12146.8 GAP91480.1 - 0.091 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aminotran_1_2 PF00155.21 GAP91481.1 - 2.1e-37 129.2 0.0 2.2e-31 109.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Zn_clus PF00172.18 GAP91483.1 - 2.6e-05 24.3 9.4 4.5e-05 23.5 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP91483.1 - 0.0016 17.6 0.1 0.0029 16.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zip PF02535.22 GAP91483.1 - 0.31 10.2 1.6 0.52 9.5 0.2 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Cyclase PF04199.13 GAP91484.1 - 2e-16 60.5 0.3 2.8e-16 60.0 0.3 1.2 1 0 0 1 1 1 1 Putative cyclase NAD_binding_8 PF13450.6 GAP91485.1 - 7.7e-06 26.0 0.3 9.5e-05 22.6 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 GAP91485.1 - 0.0075 14.7 0.0 0.014 13.9 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 GAP91485.1 - 0.12 12.3 0.5 0.31 11.0 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 GAP91485.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAP91485.1 - 0.17 11.9 0.0 0.78 9.8 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 GAP91486.1 - 4.1e-15 55.8 0.0 2.2e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP91486.1 - 1.1e-10 41.5 0.0 3.2e-06 26.9 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP91486.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 KR domain GSDH PF07995.11 GAP91487.1 - 6.1e-120 400.5 0.1 7.2e-120 400.3 0.1 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Reg_prop PF07494.11 GAP91487.1 - 0.0018 18.2 2.4 5.1 7.7 0.1 4.0 3 0 0 3 3 3 2 Two component regulator propeller NHL PF01436.21 GAP91487.1 - 0.013 15.5 0.0 0.082 13.0 0.0 2.5 3 0 0 3 3 3 0 NHL repeat WW PF00397.26 GAP91488.1 - 9.9e-10 38.3 5.8 2.9e-09 36.8 5.8 1.9 1 0 0 1 1 1 1 WW domain Peptidase_C14 PF00656.22 GAP91489.1 - 7.5e-59 199.7 0.0 9.2e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DnaJ PF00226.31 GAP91492.1 - 5.2e-10 39.3 1.9 2.1e-09 37.4 0.1 2.6 2 1 1 3 3 3 1 DnaJ domain Sugar_tr PF00083.24 GAP91493.1 - 1.3e-72 245.1 19.9 1.5e-72 244.9 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP91493.1 - 8.8e-19 67.6 34.0 1.7e-18 66.6 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_3 PF07969.11 GAP91494.1 - 2.5e-36 126.2 2.6 2.6e-28 99.7 0.7 2.3 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 GAP91494.1 - 0.00015 21.2 0.1 0.0034 16.7 0.1 2.3 1 1 0 1 1 1 1 Amidohydrolase family DUF3328 PF11807.8 GAP91495.1 - 4e-21 75.8 0.1 5.1e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_7 PF13508.7 GAP91497.1 - 1.3e-05 25.6 0.0 2.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP91497.1 - 0.00017 21.8 0.0 0.00033 20.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP91497.1 - 0.00023 21.1 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 GAP91498.1 - 5.2e-19 68.6 0.0 6.1e-18 65.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP91498.1 - 3.5e-07 29.7 0.0 3.1e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 GAP91498.1 - 9.7e-07 27.8 0.2 0.00012 20.9 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 GAP91498.1 - 7.9e-06 25.9 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 GAP91498.1 - 5e-05 23.5 0.1 0.00012 22.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAP91498.1 - 0.00037 19.9 0.6 0.00089 18.6 0.1 1.9 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 GAP91498.1 - 0.00047 19.5 0.0 0.0015 17.8 0.1 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 GAP91498.1 - 0.0009 18.9 0.4 0.0014 18.3 0.3 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAP91498.1 - 0.0025 17.1 0.3 0.13 11.5 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP91498.1 - 0.0043 16.2 4.4 0.012 14.7 1.2 2.4 2 1 1 3 3 3 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 GAP91498.1 - 0.0051 15.7 0.2 0.0083 15.0 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 GAP91498.1 - 0.0052 15.9 0.1 0.025 13.7 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 GAP91498.1 - 0.011 15.2 0.5 0.011 15.2 0.5 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 GAP91498.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 GAP91498.1 - 0.024 14.0 2.5 0.069 12.4 0.1 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase MFS_1 PF07690.16 GAP91499.1 - 2.5e-37 128.6 54.6 2.5e-37 128.6 54.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily OAD_gamma PF04277.13 GAP91499.1 - 0.29 11.8 1.8 0.74 10.4 0.3 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CPP1-like PF11833.8 GAP91499.1 - 3.9 7.1 7.0 14 5.3 0.1 3.4 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MerB PF03243.15 GAP91500.1 - 1.4e-34 118.9 0.1 2.4e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 Alkylmercury lyase LexA_DNA_bind PF01726.16 GAP91500.1 - 0.045 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain HMGL-like PF00682.19 GAP91501.1 - 4e-60 203.6 0.0 6.7e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 HMGL-like Ank_2 PF12796.7 GAP91502.1 - 5.2e-29 100.7 8.2 1e-10 42.1 1.8 4.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP91502.1 - 1.2e-25 89.6 3.3 3.3e-06 27.6 0.3 6.7 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAP91502.1 - 2.4e-22 78.3 7.8 5.7e-05 23.4 0.4 7.2 6 1 1 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 GAP91502.1 - 1.1e-20 73.4 5.0 3.1e-05 24.1 1.0 6.1 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP91502.1 - 9.2e-18 62.5 5.0 0.0093 16.4 0.1 7.9 6 1 1 7 7 7 5 Ankyrin repeat AAA_29 PF13555.6 GAP91502.1 - 0.011 15.4 0.0 0.04 13.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 GAP91502.1 - 0.025 14.3 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 GAP91502.1 - 0.033 14.1 0.5 0.24 11.3 0.5 2.2 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 GAP91502.1 - 0.15 12.5 0.1 0.73 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MFS_1 PF07690.16 GAP91503.1 - 5.8e-41 140.6 53.7 5.8e-41 140.6 53.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP91503.1 - 8.3e-14 50.9 24.6 2.6e-13 49.3 24.6 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Toxin_7 PF05980.12 GAP91505.1 - 1.8 8.9 11.2 0.14 12.5 5.6 1.8 2 0 0 2 2 2 0 Toxin 7 Pectate_lyase_3 PF12708.7 GAP91507.1 - 2.8e-68 230.0 16.3 5.3e-62 209.5 0.7 3.9 3 1 1 4 4 4 2 Pectate lyase superfamily protein Peptidase_S8 PF00082.22 GAP91507.1 - 7.4e-11 41.8 0.0 2.7e-09 36.7 0.0 2.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I36 PF03995.13 GAP91507.1 - 0.0034 17.3 0.1 0.013 15.4 0.1 2.0 1 0 0 1 1 1 1 Peptidase inhibitor family I36 DUF4419 PF14388.6 GAP91508.1 - 2.5e-113 378.5 0.0 3e-113 378.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) HET PF06985.11 GAP91509.1 - 8.5e-24 84.6 0.0 1.4e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Secretin_N_2 PF07655.13 GAP91510.1 - 0.0068 16.9 4.0 0.0098 16.4 4.0 1.3 1 0 0 1 1 1 1 Secretin N-terminal domain Presenilin PF01080.17 GAP91510.1 - 0.26 10.0 0.5 0.25 10.1 0.5 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 GAP91510.1 - 1.2 10.1 2.9 2.2 9.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1505 PF07403.11 GAP91510.1 - 1.3 9.3 8.6 5.2 7.3 8.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1505) Spt20 PF12090.8 GAP91510.1 - 2.4 7.7 9.9 3.7 7.1 9.9 1.2 1 0 0 1 1 1 0 Spt20 family NDUF_B8 PF05821.11 GAP91512.1 - 4.3e-08 33.2 0.4 9.1e-08 32.2 0.5 1.4 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 GAP91513.1 - 1e-64 218.5 0.3 1.6e-64 217.9 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP91513.1 - 3.5e-18 66.0 0.0 1.6e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP91513.1 - 1.6e-10 41.3 0.0 3.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAP91513.1 - 0.00041 20.2 0.0 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase HSA PF07529.13 GAP91513.1 - 0.00076 19.8 7.6 0.00076 19.8 7.6 2.5 1 1 2 3 3 3 1 HSA DBINO PF13892.6 GAP91513.1 - 0.008 16.5 8.4 0.023 15.1 8.4 1.7 1 0 0 1 1 1 1 DNA-binding domain DUF3500 PF12006.8 GAP91514.1 - 1.8e-104 349.4 0.0 2.2e-104 349.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DUF4188 PF13826.6 GAP91516.1 - 0.12 12.7 0.3 0.32 11.3 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) TcA_TcB_BD PF18276.1 GAP91517.1 - 2.2e-89 299.4 5.7 2.1e-58 197.7 0.0 2.4 1 1 1 2 2 2 2 Tc toxin complex TcA C-terminal TcB-binding domain Neuraminidase PF18413.1 GAP91517.1 - 1.1e-11 44.6 0.1 2.5e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Neuraminidase-like domain VRP1 PF03538.14 GAP91517.1 - 0.0014 18.1 0.1 0.0014 18.1 0.1 2.0 2 0 0 2 2 2 1 Salmonella virulence plasmid 28.1kDa A protein GLEYA PF10528.9 GAP91517.1 - 0.069 13.6 0.1 0.25 11.8 0.1 2.0 1 0 0 1 1 1 0 GLEYA domain PA14 PF07691.12 GAP91517.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 PA14 domain PRD PF00874.20 GAP91517.1 - 0.19 12.1 0.4 0.63 10.4 0.1 2.0 1 1 1 2 2 2 0 PRD domain F-box-like PF12937.7 GAP91518.1 - 0.00021 21.1 0.2 0.00054 19.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP91518.1 - 0.073 13.0 0.3 0.17 11.8 0.3 1.7 1 0 0 1 1 1 0 F-box domain SpvB PF03534.13 GAP91519.1 - 1.1e-98 330.1 0.1 2.6e-98 328.8 0.1 1.7 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.8 GAP91519.1 - 8.7e-30 103.4 0.2 1.1e-23 83.5 0.0 5.3 5 0 0 5 5 5 2 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.8 GAP91519.1 - 2.3e-19 70.0 0.3 5.6e-19 68.7 0.3 1.7 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.6 GAP91519.1 - 1e-07 32.4 6.9 0.00015 22.3 0.2 4.6 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 GAP91519.1 - 9 6.5 8.2 11 6.3 0.1 3.5 3 0 0 3 3 3 0 FG-GAP repeat adh_short PF00106.25 GAP91520.1 - 1.1e-23 83.8 0.0 3.6e-23 82.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP91520.1 - 3.5e-15 56.2 0.0 2.2e-14 53.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP91520.1 - 2.3e-05 24.4 0.7 0.00048 20.1 0.0 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 GAP91520.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAP91520.1 - 0.054 12.8 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 GAP91520.1 - 0.055 12.9 0.0 0.2 11.0 0.0 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase CoA_binding_3 PF13727.6 GAP91520.1 - 0.3 11.1 1.1 0.57 10.2 1.1 1.4 1 0 0 1 1 1 0 CoA-binding domain DUF308 PF03729.13 GAP91521.1 - 0.024 15.0 15.4 0.079 13.3 0.2 3.4 4 0 0 4 4 4 0 Short repeat of unknown function (DUF308) DUF4405 PF14358.6 GAP91521.1 - 0.054 14.0 0.3 0.054 14.0 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) DUF2371 PF10177.9 GAP91521.1 - 0.2 11.9 0.6 0.5 10.5 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) CPP1-like PF11833.8 GAP91521.1 - 0.23 11.1 0.1 0.23 11.1 0.1 2.3 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Peptidase_S8 PF00082.22 GAP91522.1 - 0.00093 18.5 4.6 0.019 14.2 1.0 2.5 1 1 1 2 2 2 2 Subtilase family Pkinase_Tyr PF07714.17 GAP91522.1 - 0.097 11.9 0.0 3.7 6.8 0.0 2.8 3 0 0 3 3 3 0 Protein tyrosine kinase BTB PF00651.31 GAP91524.1 - 3.5e-08 33.7 0.0 5.9e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain NACHT PF05729.12 GAP91526.1 - 1.1e-08 35.2 0.0 3.8e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 GAP91526.1 - 0.0019 18.4 0.2 0.022 15.0 0.1 2.7 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 GAP91526.1 - 0.0068 16.8 0.0 0.081 13.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 GAP91526.1 - 0.039 13.7 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 GAP91526.1 - 0.042 13.8 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 GAP91526.1 - 0.049 13.9 0.1 0.35 11.1 0.0 2.5 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 GAP91526.1 - 0.059 13.9 0.1 0.3 11.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 GAP91526.1 - 0.061 13.0 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAP91526.1 - 0.46 11.0 2.4 2.3 8.7 0.0 2.8 1 1 2 3 3 3 0 AAA domain NACHT PF05729.12 GAP91527.1 - 9.3e-07 28.9 0.3 2.8e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GAP91527.1 - 0.0009 19.7 0.0 0.0032 17.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP91527.1 - 0.0046 17.2 0.0 0.026 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Helo_like_N PF17111.5 GAP91527.1 - 0.0084 15.5 7.6 0.0063 15.9 4.8 2.1 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 GAP91527.1 - 0.009 16.2 0.5 0.042 14.0 0.0 2.3 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases RNA_helicase PF00910.22 GAP91527.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ubiquitin PF00240.23 GAP91530.1 - 5.3e-19 67.7 1.4 3.7e-14 52.2 0.5 3.2 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.8 GAP91530.1 - 0.00045 20.0 2.6 0.012 15.4 0.3 3.4 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like DUF676 PF05057.14 GAP91530.1 - 0.00077 19.0 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 GAP91530.1 - 0.0025 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAP91530.1 - 0.0026 18.4 4.5 0.0032 18.1 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP91530.1 - 0.035 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ubiquitin_2 PF14560.6 GAP91530.1 - 0.074 13.5 0.3 3.8 8.1 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-like domain DUF829 PF05705.14 GAP91530.1 - 0.17 11.8 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) FmdA_AmdA PF03069.15 GAP91531.1 - 2.2e-47 161.7 0.0 9.4e-31 107.0 0.0 2.4 1 1 1 2 2 2 2 Acetamidase/Formamidase family Glyco_hydro_61 PF03443.14 GAP91532.1 - 6.1e-44 150.4 0.0 8.2e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Bacteriocin_IIc PF10439.9 GAP91533.1 - 0.039 14.1 3.4 0.16 12.2 3.4 2.1 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF2207 PF09972.9 GAP91533.1 - 0.15 10.8 0.1 0.81 8.4 0.2 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Hydantoinase_B PF02538.14 GAP91534.1 - 0.17 10.2 0.1 0.22 9.9 0.1 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase GRAM PF02893.20 GAP91535.1 - 1.4e-28 99.1 1.2 4e-17 62.1 0.0 3.3 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 GAP91535.1 - 3.7e-28 98.3 0.0 8e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 GAP91535.1 - 4.2e-13 49.7 0.0 1.7e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 GAP91535.1 - 2e-05 24.8 0.1 0.00036 20.7 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.18 GAP91535.1 - 0.001 18.0 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 GAP91535.1 - 0.0027 18.1 0.1 0.034 14.6 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 GAP91535.1 - 0.059 13.7 0.2 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain YL1 PF05764.13 GAP91535.1 - 0.093 12.8 3.1 0.21 11.7 3.1 1.6 1 0 0 1 1 1 0 YL1 nuclear protein PH_3 PF14593.6 GAP91535.1 - 0.1 12.7 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 PH domain TFIIE-A_C PF11521.8 GAP91535.1 - 5.9 7.3 6.3 3.5 8.0 0.1 3.0 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Helicase_C_2 PF13307.6 GAP91536.1 - 2.6e-59 200.2 0.0 5.9e-59 199.1 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 GAP91536.1 - 2e-47 161.0 0.0 3.4e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 GAP91536.1 - 0.0031 17.5 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAP91536.1 - 0.018 14.8 0.0 0.84 9.4 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 GAP91536.1 - 0.038 13.6 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain NIF PF03031.18 GAP91537.1 - 2.3e-27 95.7 0.0 5.5e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 GAP91537.1 - 3.7e-05 24.0 0.0 9.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 GAP91537.1 - 8.4e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain Cwf_Cwc_15 PF04889.12 GAP91537.1 - 0.0042 16.9 8.5 0.0042 16.9 8.5 3.3 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein Biotin_lipoyl PF00364.22 GAP91537.1 - 0.041 13.7 0.1 1 9.3 0.2 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 GAP91537.1 - 0.052 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like BRCT_3 PF18428.1 GAP91537.1 - 0.068 13.3 0.1 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF3176 PF11374.8 GAP91538.1 - 5.3e-05 23.4 8.0 0.00011 22.4 2.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3176) GRIM-19 PF06212.12 GAP91539.1 - 1.1e-22 80.4 0.2 3.2e-22 78.9 0.2 1.6 1 1 0 1 1 1 1 GRIM-19 protein Asp PF00026.23 GAP91540.1 - 2e-74 250.9 7.5 2.3e-74 250.6 7.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP91540.1 - 4.3e-11 43.4 5.7 1.1e-05 25.7 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAP91540.1 - 0.0017 19.0 2.3 0.076 13.7 0.3 3.4 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.6 GAP91540.1 - 0.0098 15.7 0.0 0.19 11.5 0.0 2.7 3 1 0 3 3 3 1 Xylanase inhibitor C-terminal Peptidase_S10 PF00450.22 GAP91541.1 - 8.2e-37 127.6 0.0 1e-35 124.0 0.0 2.4 1 1 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_28 PF00295.17 GAP91542.1 - 1e-34 120.1 5.6 1.5e-34 119.5 5.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_49 PF03718.13 GAP91542.1 - 0.45 10.5 3.7 0.42 10.6 0.2 2.5 3 0 0 3 3 3 0 Glycosyl hydrolase family 49 TENA_THI-4 PF03070.16 GAP91543.1 - 2e-06 27.8 1.2 4.4e-06 26.7 1.2 1.6 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Isochorismatase PF00857.20 GAP91544.1 - 1.4e-16 61.2 0.0 2.5e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family Na_H_Exchanger PF00999.21 GAP91545.1 - 4.7e-33 114.5 9.0 5.5e-33 114.3 9.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 GAP91545.1 - 0.01 15.9 0.1 0.047 13.8 0.1 2.1 1 0 0 1 1 1 0 YrhC-like protein 7TM_GPCR_Srd PF10317.9 GAP91545.1 - 0.1 11.8 0.2 0.1 11.8 0.2 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd Glyco_transf_90 PF05686.12 GAP91546.1 - 1.9e-19 69.9 4.7 1.2e-15 57.4 0.4 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 GAP91546.1 - 0.21 12.0 1.9 2.1 8.8 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferases group 1 HET PF06985.11 GAP91549.1 - 1.5e-21 77.3 0.0 1.1e-20 74.5 0.0 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) pPIWI_RE_REase PF18154.1 GAP91549.1 - 0.13 12.2 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 REase associating with pPIWI_RE DUF1768 PF08719.11 GAP91551.1 - 2.3e-08 34.4 0.0 3.5e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) HET PF06985.11 GAP91553.1 - 3.2e-23 82.7 0.0 5.7e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mito_carr PF00153.27 GAP91554.1 - 1e-46 156.8 4.9 1.6e-16 60.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein FHIPEP PF00771.20 GAP91554.1 - 0.058 11.9 0.3 0.084 11.3 0.3 1.1 1 0 0 1 1 1 0 FHIPEP family Ank_2 PF12796.7 GAP91555.1 - 7.1e-30 103.4 0.2 1e-08 35.6 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) NACHT_N PF17100.5 GAP91555.1 - 6.3e-29 101.4 6.5 8.5e-29 101.0 4.8 2.1 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Ank_4 PF13637.6 GAP91555.1 - 1.8e-20 73.0 0.0 5.6e-06 26.8 0.0 4.6 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 GAP91555.1 - 3.1e-16 59.0 0.0 0.25 11.8 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 GAP91555.1 - 2.7e-15 54.9 0.0 0.4 11.4 0.0 7.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 GAP91555.1 - 6.9e-15 54.9 0.0 0.0012 19.1 0.0 5.4 3 2 3 6 6 5 5 Ankyrin repeats (many copies) NACHT PF05729.12 GAP91555.1 - 3.6e-05 23.7 0.0 9.8e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP91555.1 - 0.016 15.6 0.1 0.12 12.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 GAP91555.1 - 0.14 12.2 1.0 0.79 9.8 0.0 2.7 3 1 1 4 4 4 0 AAA domain DUF2436 PF10365.9 GAP91555.1 - 0.21 11.3 0.6 2.5 7.8 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2436) Rib_recp_KP_reg PF05104.12 GAP91555.1 - 0.5 11.4 2.3 0.96 10.5 2.3 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Serine_rich PF08824.10 GAP91555.1 - 1.3 9.0 5.9 0.77 9.7 1.6 2.4 2 0 0 2 2 2 0 Serine rich protein interaction domain FAD_binding_4 PF01565.23 GAP91556.1 - 9.1e-27 93.5 6.0 1.4e-26 92.9 6.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP91556.1 - 6.4e-10 39.0 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like EI24 PF07264.11 GAP91557.1 - 1.2e-11 45.2 14.1 1.6e-11 44.7 14.1 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2417 PF10329.9 GAP91557.1 - 8.7 5.7 7.8 4.2 6.7 4.5 1.9 2 0 0 2 2 2 0 Region of unknown function (DUF2417) ADH_N PF08240.12 GAP91559.1 - 1.4e-28 98.9 0.2 2.7e-28 98.0 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Acetyltransf_1 PF00583.25 GAP91559.1 - 6.6e-14 52.1 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP91559.1 - 4.3e-09 36.4 0.0 7.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP91559.1 - 2.6e-08 34.2 0.1 5.8e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ADH_N_assoc PF13823.6 GAP91559.1 - 4e-08 33.0 0.7 1.2e-07 31.6 0.7 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 GAP91559.1 - 9.5e-08 32.1 0.4 2.3e-07 30.8 0.4 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FR47 PF08445.10 GAP91559.1 - 4.7e-05 23.3 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAP91559.1 - 0.00062 19.9 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glu_dehyd_C PF16912.5 GAP91559.1 - 0.0016 18.0 0.1 0.0034 16.9 0.1 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Acetyltransf_CG PF14542.6 GAP91559.1 - 0.0016 18.5 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 GAP91559.1 - 0.0019 18.9 0.0 0.003 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HI0933_like PF03486.14 GAP91559.1 - 0.0089 14.8 0.1 0.016 14.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 GAP91559.1 - 0.015 14.6 0.5 0.026 13.8 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 GAP91559.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Acetyltransf_9 PF13527.7 GAP91559.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CPSase_L_D2 PF02786.17 GAP91561.1 - 3.4e-58 196.6 0.1 5e-58 196.1 0.1 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 GAP91561.1 - 1.5e-28 99.0 0.0 4.5e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 GAP91561.1 - 1.7e-28 99.4 0.0 3.3e-26 92.0 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 GAP91561.1 - 4.3e-12 45.7 0.8 1.3e-11 44.1 0.3 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 GAP91561.1 - 6.7e-08 32.3 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 GAP91561.1 - 1.6e-05 24.7 0.1 4.1e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.22 GAP91561.1 - 6.4e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 GAP91561.1 - 0.00024 21.2 0.0 0.00056 20.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 GAP91561.1 - 0.026 14.5 0.1 0.065 13.2 0.1 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.6 GAP91561.1 - 0.042 13.1 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 GAP91561.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon HlyD_3 PF13437.6 GAP91561.1 - 0.052 14.2 0.3 0.15 12.7 0.3 1.8 1 0 0 1 1 1 0 HlyD family secretion protein RimK PF08443.11 GAP91561.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.8 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Carboxyl_trans PF01039.22 GAP91562.1 - 3.8e-83 279.8 0.0 5e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain E1_dh PF00676.20 GAP91562.1 - 0.2 10.5 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component FAD_binding_2 PF00890.24 GAP91563.1 - 7.8e-47 160.3 3.2 4.7e-37 128.1 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 GAP91563.1 - 1.7e-10 40.9 0.0 2.9e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 GAP91563.1 - 3.1e-07 30.3 5.5 3.3e-07 30.2 1.5 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP91563.1 - 6.1e-07 29.0 0.3 2e-06 27.3 0.5 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP91563.1 - 9.6e-07 28.2 1.1 9.6e-07 28.2 1.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 GAP91563.1 - 1.9e-06 26.8 0.4 1.9e-06 26.8 0.4 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 GAP91563.1 - 2.4e-05 24.5 0.6 6.8e-05 23.0 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAP91563.1 - 0.00023 20.5 0.1 0.00038 19.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 GAP91563.1 - 0.0021 17.4 0.2 0.0038 16.5 0.2 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 GAP91563.1 - 0.0033 16.7 1.5 0.0064 15.8 1.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 GAP91563.1 - 0.0051 15.9 0.1 0.0076 15.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAP91563.1 - 0.0057 15.9 0.2 0.0096 15.2 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP91563.1 - 0.012 16.2 0.5 0.055 14.0 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAP91563.1 - 0.014 14.3 0.5 0.027 13.3 0.5 1.4 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.6 GAP91563.1 - 0.024 15.1 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding MFS_1 PF07690.16 GAP91564.1 - 1.2e-29 103.4 25.1 1.2e-29 103.4 25.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily HHH PF00633.23 GAP91565.1 - 0.042 13.7 0.3 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif Pkinase PF00069.25 GAP91566.1 - 9.5e-49 166.1 0.0 1.5e-48 165.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP91566.1 - 1.2e-22 80.5 0.0 1.4e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP91566.1 - 7.5e-06 25.5 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAP91566.1 - 0.00031 20.2 0.0 0.00078 18.9 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.21 GAP91566.1 - 0.031 13.5 0.0 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Aldo/keto reductase family PHR PF08005.12 GAP91566.1 - 0.11 13.1 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 PHR domain Lipase_GDSL_2 PF13472.6 GAP91567.1 - 3.5e-09 37.3 0.7 4.3e-09 37.0 0.7 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP91567.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase PPR_2 PF13041.6 GAP91568.1 - 0.02 15.1 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 PPR repeat family WD40 PF00400.32 GAP91569.1 - 5.7e-10 39.6 7.1 0.066 14.1 0.3 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Pkinase PF00069.25 GAP91570.1 - 3.6e-46 157.7 0.0 1.3e-42 146.0 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP91570.1 - 6.1e-13 48.6 0.0 3.2e-07 29.9 0.0 3.7 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 GAP91570.1 - 2.9e-06 27.4 0.0 0.0098 15.8 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 GAP91570.1 - 0.00013 21.4 0.0 0.38 10.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 GAP91570.1 - 0.018 14.7 0.1 2.3 7.8 0.0 2.5 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 GAP91570.1 - 0.024 14.0 0.0 0.1 11.9 0.0 2.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family SDA1 PF05285.12 GAP91570.1 - 0.12 11.8 13.2 0.17 11.3 13.2 1.2 1 0 0 1 1 1 0 SDA1 DUF4746 PF15928.5 GAP91570.1 - 2.8 7.3 16.6 5.2 6.4 16.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PPL5 PF18168.1 GAP91570.1 - 3.1 7.0 6.3 4.7 6.4 6.3 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Cnd1_N PF12922.7 GAP91571.1 - 4.6e-59 199.0 2.1 6.7e-59 198.5 0.1 2.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 GAP91571.1 - 4.2e-46 157.0 3.7 3.8e-42 144.1 0.1 3.8 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAP91571.1 - 9.9e-10 37.8 2.7 0.038 14.2 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 GAP91571.1 - 2.7e-09 37.3 0.8 0.00044 20.6 0.1 4.5 3 1 1 4 4 4 2 HEAT repeats Adaptin_N PF01602.20 GAP91571.1 - 6.9e-06 24.9 2.3 0.025 13.2 0.2 2.7 2 0 0 2 2 2 2 Adaptin N terminal region RTP1_C1 PF10363.9 GAP91571.1 - 4e-05 23.8 0.2 0.13 12.4 0.0 3.5 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 GAP91571.1 - 4.8e-05 23.7 5.8 0.38 11.3 0.1 5.6 5 1 0 5 5 5 2 HEAT-like repeat Cnd3 PF12719.7 GAP91571.1 - 0.0072 15.6 0.8 0.0072 15.6 0.8 3.0 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF2408 PF10303.9 GAP91571.1 - 0.13 12.8 2.9 0.46 11.1 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) MFS_1 PF07690.16 GAP91572.1 - 5.4e-12 45.3 27.2 7.9e-12 44.8 27.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAP91572.1 - 0.02 13.7 0.1 0.028 13.3 0.1 1.3 1 0 0 1 1 1 0 MFS_1 like family CDH-cyt PF16010.5 GAP91573.1 - 2.5e-39 134.8 1.9 2.9e-39 134.6 1.9 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF1996 PF09362.10 GAP91574.1 - 1.5e-72 244.4 2.3 2e-72 244.0 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Alpha_L_fucos PF01120.17 GAP91575.1 - 6.6e-76 256.0 0.1 2.1e-58 198.5 0.1 2.1 1 1 1 2 2 2 2 Alpha-L-fucosidase GHL6 PF14871.6 GAP91575.1 - 0.0083 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 ThiJ_like PF17124.5 GAP91577.1 - 7.4e-61 205.3 0.0 9e-61 205.0 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 GAP91577.1 - 1.3e-13 51.1 0.0 1.8e-12 47.4 0.0 2.3 1 1 0 1 1 1 1 DJ-1/PfpI family Hydrolase PF00702.26 GAP91578.1 - 3.7e-09 37.2 0.0 6.8e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP91578.1 - 1.6e-06 28.1 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 GAP91578.1 - 5.1e-06 26.7 0.0 1.2e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DDRGK PF09756.9 GAP91579.1 - 0.075 12.6 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 DDRGK domain CotH PF08757.11 GAP91579.1 - 0.1 12.1 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 CotH kinase protein zf-C2H2 PF00096.26 GAP91580.1 - 0.006 17.0 3.1 0.0087 16.5 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 GAP91580.1 - 0.022 14.5 4.1 0.037 13.8 0.5 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type GrpE PF01025.19 GAP91580.1 - 0.05 13.3 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 GrpE OrsD PF12013.8 GAP91580.1 - 0.07 13.6 0.4 0.07 13.6 0.4 2.3 1 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 GAP91580.1 - 0.072 14.0 7.6 0.074 13.9 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger CCDC14 PF15254.6 GAP91580.1 - 0.89 8.1 3.9 1.1 7.8 3.9 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Ribo_biogen_C PF04034.13 GAP91582.1 - 7.8e-49 164.6 0.0 1.1e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal VHS PF00790.19 GAP91583.1 - 2.3e-34 118.3 0.0 2.9e-32 111.5 0.0 2.6 1 1 0 1 1 1 1 VHS domain Alpha_adaptinC2 PF02883.20 GAP91583.1 - 1.7e-19 70.2 0.0 3.2e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 GAP91583.1 - 3e-17 62.7 1.0 6.4e-17 61.6 0.0 2.1 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 GAP91583.1 - 2.5e-08 33.4 0.1 1.5e-07 30.9 0.1 2.3 2 0 0 2 2 2 1 GGA N-GAT domain GTP_EFTU PF00009.27 GAP91584.1 - 5.9e-32 110.8 4.3 1.2e-30 106.5 4.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 GAP91584.1 - 2.9e-26 91.6 0.0 6.4e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 GAP91584.1 - 5.7e-10 39.3 0.1 1.7e-09 37.8 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 GAP91584.1 - 0.00032 20.4 0.1 0.00061 19.5 0.1 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation IF2_N PF04760.15 GAP91584.1 - 0.00096 18.9 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.21 GAP91584.1 - 0.0015 18.0 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 GAP91584.1 - 0.0029 17.8 0.7 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAP91584.1 - 0.0055 16.2 0.1 0.014 14.8 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAP91584.1 - 0.011 15.7 0.1 0.011 15.7 0.1 3.2 2 1 1 3 3 3 0 RsgA GTPase GTP_EFTU_D2 PF03144.25 GAP91584.1 - 0.023 15.1 1.1 1.8 9.0 0.0 2.8 2 0 0 2 2 2 0 Elongation factor Tu domain 2 FeoB_N PF02421.18 GAP91584.1 - 0.029 13.9 0.1 0.061 12.8 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B TrkH PF02386.16 GAP91585.1 - 2e-100 336.6 0.4 5e-95 318.8 0.0 2.1 2 0 0 2 2 2 2 Cation transport protein DUF2755 PF10954.8 GAP91585.1 - 0.19 11.7 1.8 0.86 9.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) FKBP_C PF00254.28 GAP91586.1 - 4.1e-33 113.6 0.0 6e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Acetyltransf_1 PF00583.25 GAP91588.1 - 3.4e-16 59.5 0.1 4.7e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP91588.1 - 2.3e-11 43.8 0.1 3.1e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP91588.1 - 5.5e-11 42.7 0.2 8.8e-11 42.1 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAP91588.1 - 0.00058 20.0 0.0 0.00087 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP91588.1 - 0.0053 16.8 0.0 0.0079 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP91588.1 - 0.0062 16.5 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 GAP91588.1 - 0.014 16.1 0.0 0.018 15.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IMS PF00817.20 GAP91589.1 - 9.1e-43 145.8 1.7 1.1e-42 145.6 0.4 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 GAP91589.1 - 6.2e-15 55.9 0.2 3.4e-14 53.5 0.1 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 GAP91589.1 - 0.00012 22.2 0.0 0.00035 20.7 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Sgf11 PF08209.11 GAP91589.1 - 0.077 12.6 0.1 0.2 11.2 0.1 1.8 1 1 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Alpha-L-AF_C PF06964.12 GAP91590.1 - 8.5e-24 84.6 0.0 1.5e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 GAP91590.1 - 0.0041 17.4 0.1 0.012 15.9 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain RPEL PF02755.15 GAP91591.1 - 7.9e-19 66.7 5.2 6.6e-10 38.4 1.2 2.4 2 0 0 2 2 2 2 RPEL repeat Ribonuc_L-PSP PF01042.21 GAP91592.1 - 2.9e-38 130.6 0.0 3.2e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 GAP91593.1 - 2.6e-28 99.0 22.1 2.6e-28 99.0 22.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 GAP91593.1 - 0.32 10.8 2.3 1.1 9.2 0.0 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Pec_lyase_C PF00544.19 GAP91594.1 - 1.6e-44 152.0 4.6 1.6e-44 152.0 4.6 1.5 2 0 0 2 2 2 1 Pectate lyase Acetyltransf_1 PF00583.25 GAP91595.1 - 2.8e-09 37.2 0.0 3.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP91595.1 - 0.00043 20.2 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP91595.1 - 0.0015 18.9 0.0 0.002 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sulfotransfer_4 PF17784.1 GAP91596.1 - 4.1e-34 118.3 0.0 6.6e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain TLD PF07534.16 GAP91596.1 - 1.9e-24 86.4 0.0 6.9e-24 84.7 0.0 1.9 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 GAP91596.1 - 2.2e-16 60.6 0.1 5.8e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function HIG_1_N PF04588.13 GAP91597.1 - 1.8e-21 76.1 1.9 2.9e-21 75.4 1.9 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Isy1 PF06246.12 GAP91597.1 - 0.0015 18.1 1.3 0.0021 17.7 1.3 1.2 1 0 0 1 1 1 1 Isy1-like splicing family CCCAP PF15964.5 GAP91597.1 - 0.024 13.0 5.7 0.031 12.6 5.7 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family DUF3138 PF11336.8 GAP91597.1 - 0.19 10.3 4.6 0.3 9.7 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) HNH_2 PF13391.6 GAP91598.1 - 0.015 15.4 0.2 0.044 13.9 0.2 1.8 1 0 0 1 1 1 0 HNH endonuclease Abhydrolase_6 PF12697.7 GAP91599.1 - 6.7e-11 43.2 9.4 1.1e-10 42.5 9.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP91599.1 - 0.029 14.0 0.1 0.46 10.1 0.3 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP91599.1 - 0.16 11.2 0.4 0.46 9.7 0.1 1.9 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 GAP91599.1 - 0.24 11.2 0.0 0.37 10.6 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase zf-RING_2 PF13639.6 GAP91600.1 - 5.3e-11 42.7 5.0 9.4e-11 41.9 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 GAP91600.1 - 1.5e-08 34.3 4.2 3.1e-08 33.3 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAP91600.1 - 7.7e-08 31.9 4.8 1.4e-07 31.1 4.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 GAP91600.1 - 9.2e-07 29.1 1.2 2.2e-06 27.8 1.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 GAP91600.1 - 9.2e-06 25.5 3.4 1.5e-05 24.8 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAP91600.1 - 1.8e-05 24.5 5.0 3.1e-05 23.7 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP91600.1 - 2.4e-05 24.3 6.3 4.3e-05 23.4 4.7 2.3 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 GAP91600.1 - 0.00035 20.4 4.4 0.00067 19.5 4.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 GAP91600.1 - 0.0014 18.4 2.9 0.0026 17.6 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 GAP91600.1 - 0.0031 17.6 5.5 0.006 16.7 5.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Smim3 PF17307.2 GAP91600.1 - 0.0043 16.5 2.0 0.012 15.1 2.0 1.7 1 0 0 1 1 1 1 Small integral membrane protein 3 zf-C3H2C3 PF17122.5 GAP91600.1 - 0.0065 16.5 0.5 0.015 15.3 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger zf-ANAPC11 PF12861.7 GAP91600.1 - 0.0078 16.2 1.8 0.017 15.2 1.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 GAP91600.1 - 0.036 13.4 0.2 0.051 12.9 0.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger FANCL_C PF11793.8 GAP91600.1 - 0.071 13.3 2.5 0.16 12.2 2.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 GAP91600.1 - 0.089 12.4 1.7 0.19 11.4 1.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type YdjO PF14169.6 GAP91600.1 - 0.12 12.1 0.7 2.3 8.0 0.2 2.5 2 1 0 2 2 2 0 Cold-inducible protein YdjO zf-RING_4 PF14570.6 GAP91600.1 - 0.16 11.8 1.9 0.32 10.8 1.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 GAP91600.1 - 0.35 10.7 3.0 0.86 9.5 3.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 GAP91600.1 - 0.64 10.0 6.2 0.12 12.3 0.5 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 GAP91600.1 - 1.1 9.4 3.5 2.1 8.5 3.5 1.4 1 0 0 1 1 1 0 RING-variant domain Utp11 PF03998.13 GAP91603.1 - 3.4e-57 194.2 20.1 3.9e-57 194.0 20.1 1.0 1 0 0 1 1 1 1 Utp11 protein 2OG-FeII_Oxy_3 PF13640.6 GAP91604.1 - 1.3e-08 35.6 0.0 2.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2613 PF11021.8 GAP91604.1 - 0.067 13.3 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) GST_N_3 PF13417.6 GAP91605.1 - 4e-22 78.4 0.1 8.2e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAP91605.1 - 2e-21 76.0 1.3 3.3e-21 75.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAP91605.1 - 1.1e-13 51.3 0.1 1.8e-13 50.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP91605.1 - 0.00018 21.5 0.6 0.00045 20.2 0.6 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAP91605.1 - 0.0056 16.9 0.0 0.024 14.8 0.0 2.0 1 1 1 2 2 2 1 Glutaredoxin GST_C PF00043.25 GAP91605.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAP91605.1 - 0.026 15.2 0.0 0.059 14.1 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 GAP91605.1 - 0.034 14.7 0.0 0.068 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cytochrom_C_asm PF01578.20 GAP91606.1 - 0.19 11.4 0.4 0.66 9.7 0.1 2.0 2 1 0 2 2 2 0 Cytochrome C assembly protein DNase_NucA_NucB PF14040.6 GAP91607.1 - 2.1e-11 44.2 0.0 3e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB DUF676 PF05057.14 GAP91608.1 - 0.033 13.7 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) WD40 PF00400.32 GAP91609.1 - 5.5e-11 42.8 0.9 2.3e-09 37.7 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP91609.1 - 0.00012 22.3 0.0 0.043 14.1 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP91609.1 - 0.07 12.1 0.0 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MARVEL PF01284.23 GAP91610.1 - 2.3e-20 73.1 21.4 2.7e-20 72.9 21.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain ketoacyl-synt PF00109.26 GAP91610.1 - 0.008 15.8 0.1 0.0087 15.7 0.1 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Oxidored_molyb PF00174.19 GAP91611.1 - 3.5e-56 189.5 0.0 5e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 GAP91611.1 - 4.7e-27 94.7 0.4 9.6e-27 93.7 0.2 1.7 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 GAP91611.1 - 1.3e-11 44.5 0.0 2.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Trypan_PARP PF05887.11 GAP91611.1 - 5.1 7.1 11.1 0.28 11.2 5.1 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Catalase PF00199.19 GAP91612.1 - 2.5e-177 589.7 0.1 3e-177 589.5 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 GAP91612.1 - 9.1e-13 48.2 0.0 2.2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive CIA30 PF08547.12 GAP91612.1 - 0.031 14.3 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Complex I intermediate-associated protein 30 (CIA30) Sugar_tr PF00083.24 GAP91613.1 - 2.3e-29 102.5 21.3 3.2e-23 82.3 9.0 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAP91613.1 - 8.2e-29 100.6 26.1 8.2e-29 100.6 26.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_10 PF13673.7 GAP91614.1 - 6.1e-08 32.7 0.0 9.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP91614.1 - 3.2e-07 30.6 0.1 5.2e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP91614.1 - 6.1e-07 29.8 0.1 9.9e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP91614.1 - 2.4e-05 24.2 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 GAP91614.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CBM_1 PF00734.18 GAP91615.1 - 1.1e-09 38.1 5.9 1.1e-09 38.1 5.9 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 GAP91615.1 - 0.0066 16.7 0.5 0.012 15.9 0.5 1.4 1 0 0 1 1 1 1 Toxin 7 Mucin PF01456.17 GAP91615.1 - 0.98 9.4 29.7 1.6 8.7 29.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Methyltransf_23 PF13489.6 GAP91616.1 - 9.2e-19 67.9 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP91616.1 - 9.2e-14 51.9 0.0 2.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP91616.1 - 1.2e-12 48.3 0.0 3.1e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP91616.1 - 8.6e-10 39.3 0.0 2.4e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP91616.1 - 1.6e-09 37.7 0.0 2.3e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP91616.1 - 5.7e-07 29.1 0.0 6.7e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 GAP91616.1 - 0.00017 21.1 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 GAP91616.1 - 0.0003 20.3 0.0 0.00069 19.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 GAP91616.1 - 0.0004 19.7 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 GAP91616.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase PrmA PF06325.13 GAP91616.1 - 0.0044 16.4 0.0 0.0097 15.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 GAP91616.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 GAP91616.1 - 0.048 13.4 0.2 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 GAP91616.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PCMT PF01135.19 GAP91616.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 GAP91616.1 - 0.18 10.7 0.0 0.8 8.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.16 GAP91616.1 - 0.22 10.1 0.1 0.95 7.9 0.0 2.0 2 1 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase HET PF06985.11 GAP91617.1 - 1.9e-11 44.5 2.2 3e-09 37.4 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PIG-S PF10510.9 GAP91619.1 - 2.2e-160 534.9 0.0 2.8e-160 534.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF3439 PF11921.8 GAP91619.1 - 0.14 12.2 5.8 0.3 11.1 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pex14_N PF04695.13 GAP91619.1 - 0.42 11.3 4.8 0.17 12.5 0.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SSP160 PF06933.11 GAP91619.1 - 1.1 7.3 11.9 1.9 6.6 11.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AMP-binding PF00501.28 GAP91620.1 - 1.2e-66 225.0 0.0 1.6e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP91620.1 - 1e-08 36.0 0.0 2.8e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Diphthamide_syn PF01866.17 GAP91621.1 - 5.9e-82 275.5 0.0 8.1e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MARVEL PF01284.23 GAP91622.1 - 0.00094 19.2 18.4 0.0013 18.8 18.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.6 GAP91622.1 - 0.0044 17.3 3.0 0.0074 16.6 3.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) zf-MYND PF01753.18 GAP91623.1 - 5.7e-05 23.1 9.8 0.00012 22.1 9.8 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 GAP91623.1 - 0.011 16.0 11.7 0.022 15.1 11.7 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 GAP91623.1 - 0.11 12.6 5.1 0.24 11.5 5.1 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 GAP91623.1 - 0.99 9.3 14.2 0.33 10.9 11.0 1.9 2 0 0 2 2 2 0 HIT zinc finger TFIIA PF03153.13 GAP91625.1 - 0.0037 17.3 9.6 0.15 12.1 7.5 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF4448 PF14610.6 GAP91626.1 - 4.4e-31 108.1 0.0 8e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF2222 PF09984.9 GAP91626.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) Pyr_redox_2 PF07992.14 GAP91628.1 - 3.5e-35 121.7 3.5 2.4e-28 99.2 0.7 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP91628.1 - 8.4e-18 64.7 0.6 1.4e-15 57.6 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP91628.1 - 6.8e-15 55.1 0.1 3.3e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP91628.1 - 1.2e-05 25.4 0.2 0.036 14.3 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 GAP91628.1 - 1.5e-05 25.3 0.3 0.0023 18.3 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 GAP91628.1 - 2e-05 24.0 1.3 0.39 9.9 0.1 3.0 2 1 1 3 3 3 2 FAD binding domain Thi4 PF01946.17 GAP91628.1 - 0.00013 21.4 0.9 0.00051 19.3 0.1 2.2 2 1 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 GAP91628.1 - 0.00052 19.5 1.7 0.00082 18.8 1.7 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 GAP91628.1 - 0.001 18.3 0.2 0.19 10.8 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 GAP91628.1 - 0.0016 17.6 7.0 0.11 11.6 0.4 2.9 2 1 0 3 3 3 2 FAD binding domain GIDA PF01134.22 GAP91628.1 - 0.0076 15.4 4.4 0.5 9.4 0.2 3.5 3 1 1 4 4 4 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 GAP91628.1 - 0.0092 16.0 0.1 4.3 7.4 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 GAP91628.1 - 0.038 12.8 0.1 0.35 9.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 GAP91628.1 - 0.2 11.2 3.6 5 6.6 0.2 2.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase PQ-loop PF04193.14 GAP91629.1 - 5.7e-22 77.3 11.3 2.2e-19 69.0 2.3 3.0 2 1 1 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 GAP91629.1 - 0.13 12.3 2.6 0.19 11.8 0.8 2.3 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Wzz PF02706.15 GAP91629.1 - 0.57 10.5 6.7 0.16 12.2 1.4 2.6 3 0 0 3 3 3 0 Chain length determinant protein CRAL_TRIO PF00650.20 GAP91630.1 - 6.4e-12 45.5 0.0 9.8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAP91630.1 - 0.00051 20.2 0.0 0.00097 19.3 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain tRNA-synt_1g PF09334.11 GAP91630.1 - 0.067 11.9 0.0 0.13 11.0 0.0 1.4 2 0 0 2 2 2 0 tRNA synthetases class I (M) Defensin_propep PF00879.18 GAP91630.1 - 1.1 9.6 6.9 3.5 8.0 6.9 1.9 1 0 0 1 1 1 0 Defensin propeptide NPR2 PF06218.11 GAP91631.1 - 1.8e-121 406.0 0.0 1.9e-120 402.6 0.0 2.4 1 1 0 1 1 1 1 Nitrogen permease regulator 2 DUF2278 PF10042.9 GAP91631.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) tRNA-synt_1b PF00579.25 GAP91632.1 - 1.2e-71 241.4 0.0 1.6e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 GAP91632.1 - 1e-42 144.8 0.0 2e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain Glyco_hydro_18 PF00704.28 GAP91633.1 - 3.8e-68 230.5 1.5 6.1e-68 229.8 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 GAP91633.1 - 1.8e-06 28.3 10.6 1.8e-06 28.3 10.6 4.7 4 0 0 4 4 4 1 Chitin recognition protein FAM163 PF15069.6 GAP91633.1 - 0.027 14.9 0.9 0.24 11.9 0.1 2.4 2 0 0 2 2 2 0 FAM163 family LysM PF01476.20 GAP91634.1 - 2.1e-21 75.7 2.4 6e-05 23.0 0.1 5.0 5 0 0 5 5 5 4 LysM domain F-box-like PF12937.7 GAP91635.1 - 0.074 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box-like CybS PF05328.12 GAP91636.1 - 5e-55 184.8 0.0 6.4e-55 184.5 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Vps53_N PF04100.12 GAP91637.1 - 4.2e-103 345.2 0.0 7.2e-103 344.5 0.0 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 GAP91637.1 - 1.2e-07 31.3 1.4 2.2e-07 30.5 1.4 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 GAP91637.1 - 9.1e-06 25.6 0.2 1.9e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Sec6 PF06046.13 GAP91637.1 - 1.1e-05 24.1 1.2 0.00051 18.6 1.1 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec6 RINT1_TIP1 PF04437.13 GAP91637.1 - 0.00021 20.3 2.8 0.018 14.0 0.5 3.1 3 1 0 3 3 3 1 RINT-1 / TIP-1 family VPS53_C PF16854.5 GAP91637.1 - 0.02 14.8 0.0 0.35 10.7 0.0 2.3 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus Imm43 PF15570.6 GAP91637.1 - 0.098 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 43 DUF5082 PF16888.5 GAP91637.1 - 0.1 12.9 0.4 0.4 11.0 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Seryl_tRNA_N PF02403.22 GAP91637.1 - 0.38 11.0 2.0 2.3 8.5 0.3 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ubiquitin PF00240.23 GAP91638.1 - 6.9e-19 67.4 0.0 1.1e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 GAP91638.1 - 7.8e-07 28.9 2.2 2.5e-06 27.3 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 GAP91638.1 - 0.00099 19.2 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAP91638.1 - 0.002 18.7 0.0 0.0049 17.4 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 GAP91638.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 GAP91638.1 - 0.048 13.7 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair DUF3123 PF11321.8 GAP91638.1 - 8.4 7.1 10.0 0.47 11.1 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) ADH_zinc_N PF00107.26 GAP91639.1 - 3.4e-30 104.7 1.1 4.9e-30 104.2 1.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP91639.1 - 8e-12 46.4 0.0 1.4e-11 45.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP91639.1 - 7.5e-05 22.6 0.0 0.00021 21.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 GAP91639.1 - 0.016 14.6 0.8 0.024 13.9 0.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 GAP91639.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain HupF_HypC PF01455.18 GAP91639.1 - 0.27 11.4 1.7 0.6 10.3 0.2 2.3 2 1 1 3 3 3 0 HupF/HypC family Lactamase_B PF00753.27 GAP91640.1 - 1.2e-05 25.4 0.2 2.4e-05 24.5 0.2 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HypA PF01155.19 GAP91640.1 - 0.078 13.0 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RecR PF02132.15 GAP91640.1 - 0.42 10.2 3.0 0.85 9.2 3.0 1.4 1 0 0 1 1 1 0 RecR protein Amidase PF01425.21 GAP91641.1 - 1.8e-94 317.3 0.0 2.2e-94 317.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Alpha_kinase PF02816.18 GAP91642.1 - 1.2e-45 155.9 0.0 1.3e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Alpha-kinase family Peptidase_S9 PF00326.21 GAP91643.1 - 2.6e-37 128.4 0.2 4e-37 127.8 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 GAP91643.1 - 2.8e-13 49.4 1.3 3.7e-07 29.9 0.5 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.7 GAP91643.1 - 1.7e-07 32.1 11.2 5.6e-07 30.4 9.5 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP91643.1 - 2.5e-07 30.6 1.5 4.5e-05 23.2 2.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 GAP91643.1 - 1.4e-06 28.0 0.1 0.0045 16.6 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family LIP PF03583.14 GAP91643.1 - 3.7e-06 26.5 0.6 1.1e-05 24.9 0.6 1.7 2 0 0 2 2 2 1 Secretory lipase Hydrolase_4 PF12146.8 GAP91643.1 - 9.4e-05 21.8 1.0 0.048 12.9 1.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 GAP91643.1 - 0.00034 20.5 0.0 0.91 9.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 GAP91643.1 - 0.00056 19.8 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DPPIV_N PF00930.21 GAP91643.1 - 0.001 17.9 0.0 0.0057 15.5 0.0 2.2 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_4 PF08386.10 GAP91643.1 - 0.0083 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Esterase_phd PF10503.9 GAP91643.1 - 0.019 14.5 0.3 0.14 11.6 0.2 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase COesterase PF00135.28 GAP91643.1 - 0.16 10.8 0.3 0.24 10.2 0.3 1.2 1 0 0 1 1 1 0 Carboxylesterase family Acetyltransf_1 PF00583.25 GAP91645.1 - 5e-17 62.2 0.0 6.6e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP91645.1 - 6.9e-14 51.9 0.0 9.5e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP91645.1 - 1.4e-13 51.1 0.0 2.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP91645.1 - 5.6e-09 35.9 0.1 1.3e-08 34.7 0.1 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 GAP91645.1 - 1.7e-06 28.3 0.0 6.1e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 GAP91645.1 - 0.0002 22.1 0.0 0.00025 21.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAP91645.1 - 0.0022 18.1 0.1 0.0052 16.9 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 GAP91645.1 - 0.055 13.6 0.0 0.089 12.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-CCCH PF00642.24 GAP91646.1 - 1.6e-08 34.3 18.9 3.4e-07 30.0 2.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 GAP91646.1 - 0.0065 16.5 3.3 0.0065 16.5 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain RRM_1 PF00076.22 GAP91646.1 - 0.01 15.6 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 GAP91646.1 - 0.012 16.3 2.2 0.59 10.8 0.2 2.3 2 0 0 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 GAP91646.1 - 0.059 13.6 2.2 0.28 11.4 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Oxysterol_BP PF01237.18 GAP91647.1 - 8.5e-89 298.0 0.0 3e-86 289.6 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Glyco_transf_22 PF03901.17 GAP91649.1 - 3.2e-37 128.8 13.8 4.5e-37 128.3 13.8 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Yos1 PF08571.10 GAP91650.1 - 4e-33 113.5 1.0 4.5e-33 113.3 1.0 1.0 1 0 0 1 1 1 1 Yos1-like UCH PF00443.29 GAP91651.1 - 1.9e-53 181.6 0.0 1.9e-53 181.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAP91651.1 - 8.3e-26 91.3 1.2 1.8e-19 70.5 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Activator-TraM PF11657.8 GAP91651.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.2 2 0 0 2 2 2 0 Transcriptional activator TraM DUF4746 PF15928.5 GAP91651.1 - 1.7 8.0 15.1 3.7 6.9 15.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Peptidase_C98 PF15499.6 GAP91651.1 - 6 6.2 13.9 0.32 10.4 0.7 3.1 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Bud13 PF09736.9 GAP91651.1 - 6.8 7.1 20.2 19 5.6 18.1 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex RR_TM4-6 PF06459.12 GAP91651.1 - 8 6.2 15.8 19 5.0 15.8 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mito_carr PF00153.27 GAP91652.1 - 7.1e-49 163.7 5.3 1.5e-17 63.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.28 GAP91653.1 - 0.00032 21.1 0.1 1.7 9.2 0.1 3.2 2 1 0 2 2 2 2 CBS domain CW_binding_2 PF04122.12 GAP91654.1 - 0.11 13.1 0.2 0.29 11.8 0.2 1.7 1 1 1 2 2 2 0 Putative cell wall binding repeat 2 Epimerase PF01370.21 GAP91655.1 - 4.5e-18 65.6 0.0 6e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAP91655.1 - 3.5e-08 32.9 0.0 5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 GAP91655.1 - 1e-05 24.7 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 GAP91655.1 - 2.8e-05 23.7 0.0 3.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 GAP91655.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 GAP91655.1 - 0.021 15.1 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 GAP91655.1 - 0.19 11.2 0.0 0.55 9.6 0.0 1.8 1 1 0 1 1 1 0 short chain dehydrogenase F_actin_cap_B PF01115.17 GAP91656.1 - 2.5e-101 338.3 0.0 2.9e-101 338.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit BAH PF01426.18 GAP91657.1 - 0.00011 22.1 0.1 0.00023 21.0 0.1 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 GAP91657.1 - 0.0047 16.8 5.1 0.0054 16.6 2.4 2.2 2 0 0 2 2 2 1 PHD-finger ATG22 PF11700.8 GAP91658.1 - 3.7e-169 563.4 16.1 4.6e-169 563.1 16.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 GAP91658.1 - 0.00013 21.0 6.2 0.00013 21.0 6.2 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily TRAP-gamma PF07074.12 GAP91658.1 - 0.14 11.7 0.7 0.41 10.2 0.7 1.7 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Glyco_hydro_10 PF00331.20 GAP91659.1 - 6e-32 111.1 0.2 6.7e-32 110.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_127 PF07944.12 GAP91660.1 - 8.2e-21 74.1 0.1 9.3e-20 70.6 0.1 2.0 1 1 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 GAP91660.1 - 0.011 14.8 0.0 0.064 12.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Cnd1 PF12717.7 GAP91660.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 BUD22 PF09073.10 GAP91661.1 - 0.14 11.5 4.9 0.16 11.2 4.9 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 GAP91661.1 - 0.15 11.9 5.7 0.2 11.5 5.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 GAP91661.1 - 0.22 9.7 8.7 0.27 9.4 8.7 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 GAP91661.1 - 1.3 8.4 9.5 1.6 8.0 9.5 1.1 1 0 0 1 1 1 0 SDA1 DUF4637 PF15470.6 GAP91661.1 - 1.3 8.8 5.1 0.72 9.6 2.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) GEN1_C PF18380.1 GAP91661.1 - 1.7 9.6 5.4 1.1 10.2 3.5 1.6 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain RXT2_N PF08595.11 GAP91661.1 - 2.1 8.4 6.7 3.7 7.6 6.7 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 GAP91661.1 - 5 5.1 22.6 6.6 4.7 22.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi Rhamno_transf PF11316.8 GAP91661.1 - 5.4 6.3 6.1 9.5 5.5 6.1 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase CDC45 PF02724.14 GAP91661.1 - 6.7 4.9 10.0 8.7 4.5 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Asp_protease_2 PF13650.6 GAP91662.1 - 1.2e-22 80.4 0.0 5.6e-10 39.7 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 GAP91662.1 - 6.1e-22 78.0 0.0 1.4e-09 38.4 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 GAP91662.1 - 5.7e-07 29.4 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.10 GAP91662.1 - 5.2e-06 26.3 0.0 0.00058 19.6 0.0 2.3 2 0 0 2 2 2 2 Aspartyl protease RVP PF00077.20 GAP91662.1 - 1.3e-05 25.4 0.0 0.017 15.4 0.0 3.0 2 1 0 2 2 2 2 Retroviral aspartyl protease DUF5518 PF17647.1 GAP91663.1 - 0.38 10.9 10.3 0.78 9.9 10.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5518) C2 PF00168.30 GAP91664.1 - 1.5e-79 262.9 0.0 4.6e-22 78.2 0.0 5.6 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 GAP91664.1 - 0.0003 20.3 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain FKBP_C PF00254.28 GAP91664.1 - 0.051 13.9 0.0 0.69 10.3 0.0 2.5 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase MLVIN_C PF18697.1 GAP91664.1 - 0.06 13.4 0.0 0.88 9.7 0.0 2.6 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain ThiS PF02597.20 GAP91665.1 - 3.3e-08 34.0 0.0 1e-07 32.5 0.0 1.7 1 1 0 1 1 1 1 ThiS family Mob1_phocein PF03637.17 GAP91666.1 - 1.8e-43 148.5 0.1 3.6e-43 147.5 0.1 1.5 1 1 0 1 1 1 1 Mob1/phocein family Leo1 PF04004.13 GAP91667.1 - 1.2e-28 100.0 0.2 1.2e-28 100.0 0.2 2.0 2 0 0 2 2 2 1 Leo1-like protein DUF3336 PF11815.8 GAP91668.1 - 1.2e-33 115.7 0.6 7.8e-33 113.1 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 GAP91668.1 - 8.2e-13 49.0 0.0 2e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase BOP1NT PF08145.12 GAP91671.1 - 9.6e-104 346.9 7.7 1.3e-103 346.4 7.7 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 GAP91671.1 - 4.5e-24 84.3 11.0 1.1e-08 35.5 0.7 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP91671.1 - 6.7e-06 26.3 0.0 0.088 13.1 0.0 4.4 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nop53 PF07767.11 GAP91671.1 - 0.029 13.8 0.1 0.029 13.8 0.1 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) FAA_hydrolase PF01557.18 GAP91672.1 - 8e-65 218.6 0.0 9.8e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 GAP91672.1 - 0.035 14.5 0.1 0.058 13.8 0.1 1.3 1 0 0 1 1 1 0 Type II transport protein GspH PAS_5 PF07310.13 GAP91672.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 PAS domain DUF4140 PF13600.6 GAP91673.1 - 5.4 7.5 11.3 6.6 7.2 5.6 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) BRO1 PF03097.18 GAP91674.1 - 5.3e-08 32.1 0.1 6.8e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 BRO1-like domain Alg6_Alg8 PF03155.15 GAP91675.1 - 1e-130 437.0 26.3 5.9e-83 279.5 10.1 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family NPP1 PF05630.11 GAP91676.1 - 8.9e-56 189.1 0.4 1e-55 188.9 0.4 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) C2 PF00168.30 GAP91677.1 - 2.6e-11 43.7 0.0 4.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain S-methyl_trans PF02574.16 GAP91678.1 - 1.8e-56 191.9 0.0 2.1e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Methyltransf_11 PF08241.12 GAP91680.1 - 1e-19 70.9 0.0 2.3e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP91680.1 - 1.3e-18 67.5 0.0 2.9e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP91680.1 - 3e-17 62.8 0.0 4.5e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP91680.1 - 2.1e-12 47.2 0.0 4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP91680.1 - 9.9e-11 42.3 0.0 2.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP91680.1 - 2.4e-10 40.2 0.0 4.1e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 GAP91680.1 - 7e-09 35.4 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 GAP91680.1 - 7e-06 25.8 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 GAP91680.1 - 0.0003 20.4 0.0 0.00048 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 GAP91680.1 - 0.0021 18.1 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAP91680.1 - 0.0054 16.5 0.0 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 GAP91680.1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain TehB PF03848.14 GAP91680.1 - 0.048 13.1 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 GAP91680.1 - 0.05 13.4 0.0 1 9.1 0.0 2.4 1 1 0 1 1 1 0 Hypothetical methyltransferase PrmA PF06325.13 GAP91680.1 - 0.064 12.6 0.0 0.089 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 GAP91680.1 - 0.096 11.8 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.17 GAP91680.1 - 0.098 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Prok-RING_1 PF14446.6 GAP91681.1 - 0.047 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 VIR_N PF15912.5 GAP91681.1 - 3.4 7.2 8.6 7.6 6.0 8.6 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal MFS_1 PF07690.16 GAP91683.1 - 1.5e-24 86.6 36.5 1.5e-24 86.6 36.5 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP91683.1 - 2.4e-05 23.4 15.3 0.00028 19.9 15.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Tannase PF07519.11 GAP91684.1 - 8.6e-58 196.4 7.2 5e-56 190.5 0.6 2.5 2 0 0 2 2 2 2 Tannase and feruloyl esterase Methyltransf_2 PF00891.18 GAP91685.1 - 8.1e-25 87.3 0.0 5.7e-24 84.6 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase domain Phage_rep_org_N PF09681.10 GAP91685.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Dimerisation2 PF16864.5 GAP91685.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain UbiA PF01040.18 GAP91687.1 - 5.5e-38 130.7 15.4 7.6e-38 130.2 15.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family HET PF06985.11 GAP91688.1 - 4.6e-20 72.5 0.0 7.1e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hydrolase_4 PF12146.8 GAP91689.1 - 5.5e-12 45.5 0.0 8.9e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAP91689.1 - 7.6e-11 43.0 2.8 1.2e-10 42.3 2.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP91689.1 - 1.4e-10 41.2 0.1 3.1e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 GAP91689.1 - 2.2e-05 24.2 0.0 3.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 GAP91689.1 - 0.0032 17.1 0.0 0.021 14.4 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 GAP91689.1 - 0.17 11.6 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family dCMP_cyt_deam_1 PF00383.23 GAP91691.1 - 2.8e-15 56.0 0.5 4e-15 55.5 0.5 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 GAP91691.1 - 2.1e-08 34.5 2.9 2.5e-07 30.9 0.3 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 GAP91691.1 - 0.0054 16.4 1.2 0.67 9.5 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Sugar_tr PF00083.24 GAP91692.1 - 6.5e-100 335.1 31.3 7.9e-100 334.8 31.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP91692.1 - 3.7e-22 78.7 27.2 3.7e-22 78.7 27.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sirohm_synth_M PF14824.6 GAP91695.1 - 0.063 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central p450 PF00067.22 GAP91697.1 - 1.1e-71 241.9 0.0 1.4e-71 241.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Choline_kinase PF01633.20 GAP91698.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 GAP91698.1 - 0.0028 17.0 0.0 0.0064 15.8 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase APH PF01636.23 GAP91698.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_18 PF13238.6 GAP91699.1 - 0.0047 17.5 0.2 1.1 9.8 0.2 3.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAP91699.1 - 0.011 16.1 0.0 0.58 10.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 GAP91699.1 - 0.031 14.3 0.1 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 GAP91699.1 - 0.038 14.4 0.0 0.85 10.1 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 GAP91699.1 - 0.07 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase CPT PF07931.12 GAP91699.1 - 0.09 12.6 0.2 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 GAP91699.1 - 0.097 12.1 0.0 0.4 10.1 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF463 PF04317.12 GAP91699.1 - 0.098 11.6 0.1 0.21 10.5 0.0 1.5 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_29 PF13555.6 GAP91699.1 - 0.15 11.8 0.2 0.68 9.7 0.0 2.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.6 GAP91699.1 - 0.16 12.1 0.1 0.77 9.9 0.0 2.3 2 2 0 2 2 2 0 AAA domain NUDIX PF00293.28 GAP91700.1 - 8.9e-08 32.2 1.4 2.1e-07 31.0 1.4 1.6 1 1 0 1 1 1 1 NUDIX domain Amidase PF01425.21 GAP91701.1 - 1.8e-74 251.3 0.9 8e-74 249.2 0.9 1.8 1 1 0 1 1 1 1 Amidase NmrA PF05368.13 GAP91702.1 - 1.9e-09 37.4 0.0 2.3e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Zn_clus PF00172.18 GAP91704.1 - 1.3e-05 25.2 11.6 1.3e-05 25.2 11.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM217 PF15344.6 GAP91704.1 - 0.1 12.5 4.3 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 FAM217 family IMUP PF15761.5 GAP91704.1 - 0.56 10.9 12.3 4.5 8.0 1.3 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein DPBB_1 PF03330.18 GAP91706.1 - 4.7e-05 23.6 0.1 0.00011 22.4 0.1 1.7 1 1 0 1 1 1 1 Lytic transglycolase Abhydrolase_2 PF02230.16 GAP91707.1 - 2e-27 96.4 0.0 1.5e-20 73.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAP91707.1 - 0.00054 19.5 0.0 0.0096 15.4 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.13 GAP91707.1 - 0.049 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 GAP91707.1 - 0.12 11.6 0.0 19 4.4 0.0 2.5 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Cutinase PF01083.22 GAP91707.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase APH PF01636.23 GAP91708.1 - 3.4e-12 46.8 0.0 4.9e-12 46.3 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP91708.1 - 3.2e-07 30.1 0.0 6.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 GAP91708.1 - 0.00055 18.9 0.3 0.26 10.1 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Pkinase PF00069.25 GAP91708.1 - 0.0094 15.3 0.1 0.16 11.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP91708.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 GAP91708.1 - 0.047 13.3 0.4 9 5.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DUF1593 PF07632.11 GAP91710.1 - 8.8e-88 294.1 0.0 1.2e-87 293.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 GAP91710.1 - 0.012 14.5 0.1 0.018 13.9 0.1 1.2 1 0 0 1 1 1 0 REJ domain DUF4609 PF15382.6 GAP91710.1 - 0.1 12.5 1.6 1.8 8.5 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4609) Cupin_2 PF07883.11 GAP91711.1 - 1.7e-08 34.0 0.0 2.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 GAP91711.1 - 0.18 11.6 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Alpha-amylase PF00128.24 GAP91712.1 - 7.5e-56 190.1 2.2 4.6e-54 184.2 2.2 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 GAP91712.1 - 0.0028 15.9 0.4 0.035 12.3 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 70 hDGE_amylase PF14701.6 GAP91712.1 - 0.005 16.0 0.0 0.0071 15.5 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF1966 PF09260.11 GAP91712.1 - 0.011 15.9 0.0 0.094 13.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) Cellulase PF00150.18 GAP91712.1 - 0.025 14.0 0.1 0.089 12.2 0.0 1.9 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) NSP10 PF09401.10 GAP91712.1 - 0.036 14.1 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA synthesis protein NSP10 Zn_clus PF00172.18 GAP91713.1 - 2.6e-08 33.8 12.1 4.4e-08 33.1 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAP91713.1 - 6.9e-06 25.1 0.2 1.2e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CLPTM1 PF05602.12 GAP91715.1 - 2.4e-153 511.2 0.0 2.9e-153 510.9 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Lysine_decarbox PF03641.14 GAP91716.1 - 2.4e-29 102.1 0.0 3.3e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 GAP91716.1 - 2.7e-06 27.1 6.9 1.2e-05 25.0 6.9 1.9 1 1 0 1 1 1 1 SLOG cluster4 family Chorismate_bind PF00425.18 GAP91717.1 - 4.3e-61 206.7 0.0 2e-55 188.2 0.0 3.3 2 1 0 2 2 2 2 chorismate binding enzyme GATase PF00117.28 GAP91717.1 - 2.7e-22 79.5 0.0 1.3e-21 77.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 GAP91717.1 - 1.5e-12 48.0 0.0 3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 GAP91717.1 - 8.6e-05 22.4 0.0 0.0002 21.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 Glyco_hydro_63 PF03200.16 GAP91718.1 - 9.4e-168 559.0 2.9 2.5e-166 554.3 0.2 3.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 GAP91718.1 - 3.7e-80 269.3 0.0 4.8e-79 265.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 GAP91718.1 - 0.00011 21.3 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Trehalase SNRNP27 PF08648.12 GAP91719.1 - 5e-27 93.7 2.2 1e-26 92.7 2.2 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DUF3433 PF11915.8 GAP91719.1 - 7.6e-23 80.8 24.0 2.8e-18 66.1 4.6 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) SP_C-Propep PF08999.10 GAP91719.1 - 0.17 11.7 0.7 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide HET PF06985.11 GAP91721.1 - 7.4e-08 32.9 0.4 0.00011 22.6 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Asp PF00026.23 GAP91722.1 - 1e-33 117.1 0.0 4.2e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 GAP91722.1 - 0.0042 17.7 0.2 26 5.5 0.0 3.4 3 0 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.6 GAP91722.1 - 0.029 14.6 0.0 0.4 10.9 0.2 2.3 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Elong_Iki1 PF10483.9 GAP91723.1 - 3.9e-29 102.1 0.0 4.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 Mucin PF01456.17 GAP91723.1 - 0.015 15.3 9.4 0.018 15.0 9.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein K_channel_TID PF07941.11 GAP91723.1 - 0.41 11.1 10.0 1.3 9.5 4.7 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Dicty_REP PF05086.12 GAP91723.1 - 1 7.3 2.9 1.1 7.2 2.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.11 GAP91723.1 - 2.3 6.2 8.2 2.6 6.0 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Proteasome PF00227.26 GAP91724.1 - 7.5e-50 169.1 0.0 9.6e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 GAP91724.1 - 4e-12 45.6 0.3 7.6e-12 44.7 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.14 GAP91725.1 - 6.1e-44 148.7 5.5 7e-44 148.5 5.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 RabGAP-TBC PF00566.18 GAP91726.1 - 4.2e-37 127.9 2.3 1e-36 126.7 2.3 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 GAP91726.1 - 9.6e-08 31.7 0.0 6.4e-05 22.5 0.0 3.2 2 1 0 2 2 2 1 Rab-binding domain (RBD) TetR_C_24 PF17932.1 GAP91726.1 - 0.062 13.6 0.3 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Mso1_Sec1_bdg PF14475.6 GAP91727.1 - 1.3e-19 69.5 0.1 2.4e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 GAP91728.1 - 2.5e-34 118.4 0.3 2.5e-34 118.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 GAP91728.1 - 2.4e-26 92.2 24.6 2.4e-26 92.2 24.6 2.7 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 GAP91728.1 - 7.4e-06 25.6 20.2 9.5e-06 25.2 20.2 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 GAP91728.1 - 0.06 13.1 1.2 0.12 12.1 0.9 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain TrmO PF01980.16 GAP91728.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 tRNA-methyltransferase O Exonuc_VII_L PF02601.15 GAP91728.1 - 4.3 6.8 7.7 0.43 10.1 3.5 1.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Nop14 PF04147.12 GAP91728.1 - 8.5 4.4 34.8 12 3.9 34.8 1.2 1 0 0 1 1 1 0 Nop14-like family TrmE_N PF10396.9 GAP91729.1 - 1e-36 125.7 0.0 3.1e-36 124.2 0.0 1.9 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 GAP91729.1 - 3.6e-33 115.5 0.0 8.6e-33 114.2 0.0 1.6 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 GAP91729.1 - 1.9e-17 63.4 0.0 3.9e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 GAP91729.1 - 7.6e-05 22.3 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 GAP91729.1 - 0.00038 20.6 0.0 0.00075 19.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 GAP91729.1 - 0.011 16.2 0.0 0.035 14.6 0.0 1.8 1 1 1 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 GAP91729.1 - 0.059 13.3 0.1 0.28 11.1 0.0 2.1 3 0 0 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 GAP91729.1 - 0.15 11.6 0.0 2.6 7.5 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Med6 PF04934.14 GAP91730.1 - 4.9e-40 136.4 0.0 7e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component MMtag PF10159.9 GAP91731.1 - 1.6e-32 111.6 1.3 2.9e-32 110.8 1.3 1.4 1 0 0 1 1 1 1 Multiple myeloma tumor-associated Pollen_allerg_2 PF01620.16 GAP91731.1 - 0.052 13.7 2.4 0.44 10.7 0.6 2.4 1 1 2 3 3 3 0 Ribonuclease (pollen allergen) DUF3752 PF12572.8 GAP91731.1 - 0.13 12.8 3.0 0.24 11.9 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF3684 PF12449.8 GAP91732.1 - 0 1393.8 0.0 0 1393.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 GAP91732.1 - 0.00012 21.9 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Utp21 PF04192.12 GAP91732.1 - 0.11 12.0 0.1 0.28 10.6 0.1 1.6 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Reprolysin_5 PF13688.6 GAP91732.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12 HA2 PF04408.23 GAP91733.1 - 3.1e-25 88.6 0.0 3.1e-25 88.6 0.0 2.8 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 GAP91733.1 - 3.2e-13 50.0 0.2 3.4e-12 46.7 0.0 2.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 GAP91733.1 - 3.7e-10 40.0 0.0 1.9e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 GAP91733.1 - 1.6e-09 37.8 0.2 2.4e-08 33.9 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 GAP91733.1 - 0.0029 17.3 0.0 0.0082 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAP91733.1 - 0.0034 17.7 0.0 0.0084 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 GAP91733.1 - 0.0041 16.5 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.6 GAP91733.1 - 0.0043 17.6 5.1 0.0077 16.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 GAP91733.1 - 0.0066 16.7 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 GAP91733.1 - 0.026 13.6 0.0 0.065 12.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 GAP91733.1 - 0.03 14.9 0.1 0.98 9.9 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 GAP91733.1 - 0.03 13.9 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAP91733.1 - 0.084 13.0 0.0 0.084 13.0 0.0 2.3 3 0 0 3 3 1 0 AAA domain AAA_29 PF13555.6 GAP91733.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 GAP91733.1 - 0.19 10.9 0.0 0.19 10.9 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) PAC3 PF10178.9 GAP91734.1 - 3.4e-05 23.9 0.0 4.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 PCNA_C PF02747.15 GAP91734.1 - 0.17 12.1 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain 2OG-FeII_Oxy PF03171.20 GAP91735.1 - 6.2e-22 78.0 0.0 1.8e-21 76.5 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 GAP91735.1 - 5e-21 75.7 0.0 8.2e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Cyclase PF04199.13 GAP91736.1 - 1.3e-08 35.1 0.0 1.9e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase TPR_9 PF13371.6 GAP91736.1 - 0.13 12.4 0.1 0.7 10.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HAD_2 PF13419.6 GAP91737.1 - 2.3e-13 50.6 0.0 3.1e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP91737.1 - 0.00054 20.0 0.1 0.0014 18.7 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 GAP91737.1 - 0.0014 19.0 0.0 0.0018 18.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Metallophos PF00149.28 GAP91738.1 - 2.6e-38 132.6 0.1 5.4e-38 131.6 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.6 GAP91739.1 - 3e-57 193.9 2.8 6.3e-57 192.8 2.8 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP91739.1 - 3.3e-32 111.6 4.8 1.7e-31 109.2 4.8 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP91739.1 - 5e-07 29.8 0.2 5e-07 29.8 0.2 1.8 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 GAP91739.1 - 0.01 15.2 0.1 0.022 14.2 0.1 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 GAP91739.1 - 0.017 15.4 0.3 0.031 14.5 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain YjeF_N PF03853.15 GAP91739.1 - 0.034 14.0 0.2 0.054 13.4 0.2 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.21 GAP91739.1 - 0.071 12.6 0.1 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 GAP91739.1 - 0.1 12.4 0.3 0.16 11.8 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 GAP91739.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Toprim PF01751.22 GAP91739.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Toprim domain TauD PF02668.16 GAP91740.1 - 2.2e-34 119.5 0.0 3.1e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 GAP91740.1 - 4.6e-11 43.2 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) PhoD PF09423.10 GAP91742.1 - 1.2e-42 146.2 0.0 2.6e-42 145.1 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase EMP24_GP25L PF01105.24 GAP91743.1 - 3e-47 160.9 0.9 3.4e-47 160.7 0.9 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MepB PF08877.10 GAP91743.1 - 0.073 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 MepB protein SKIP_SNW PF02731.15 GAP91744.1 - 3.8e-69 231.5 3.5 3.8e-69 231.5 3.5 2.1 2 0 0 2 2 2 1 SKIP/SNW domain UBD PF16455.5 GAP91745.1 - 4.2e-37 126.6 0.0 7.6e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 GAP91745.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 GAP91745.1 - 0.00073 19.3 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 GAP91745.1 - 0.00097 19.7 0.0 0.0033 18.0 0.0 1.9 1 1 1 2 2 2 1 DUF2407 ubiquitin-like domain DUF4141 PF13605.6 GAP91745.1 - 0.024 13.9 0.1 0.054 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) RVT_1 PF00078.27 GAP91746.1 - 0.029 13.9 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PBP1_TM PF14812.6 GAP91747.1 - 6.9e-06 26.3 1.6 6.9e-06 26.3 1.6 2.4 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Plasmodium_Vir PF05795.11 GAP91747.1 - 8.7e-06 25.4 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Amnionless PF14828.6 GAP91747.1 - 0.00089 18.2 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Amnionless CDC27 PF09507.10 GAP91747.1 - 0.00097 18.6 0.2 0.0012 18.4 0.2 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF2457 PF10446.9 GAP91747.1 - 0.0031 16.7 4.1 0.0031 16.7 4.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) TMEM51 PF15345.6 GAP91747.1 - 0.0041 17.0 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 CDC45 PF02724.14 GAP91747.1 - 0.0083 14.5 5.2 0.012 13.9 5.2 1.2 1 0 0 1 1 1 1 CDC45-like protein LapA_dom PF06305.11 GAP91747.1 - 0.012 15.5 0.4 0.012 15.5 0.4 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain LPG_synthase_TM PF03706.13 GAP91747.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region FAM176 PF14851.6 GAP91747.1 - 0.013 15.2 9.4 0.58 9.8 0.0 2.2 1 1 1 2 2 2 0 FAM176 family Mid2 PF04478.12 GAP91747.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor HemY_N PF07219.13 GAP91747.1 - 0.02 15.1 0.4 0.045 13.9 0.4 1.5 1 0 0 1 1 1 0 HemY protein N-terminus DUF4381 PF14316.6 GAP91747.1 - 0.022 15.0 0.1 0.049 13.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 GAP91747.1 - 0.028 15.3 0.0 0.067 14.1 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DNA_pol_phi PF04931.13 GAP91747.1 - 0.029 12.5 2.6 0.036 12.2 2.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi NicO PF03824.16 GAP91747.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Phage_holin_2_1 PF04971.12 GAP91747.1 - 0.053 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S OAD_gamma PF04277.13 GAP91747.1 - 0.071 13.7 0.0 0.3 11.7 0.0 2.1 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Orf78 PF06024.12 GAP91747.1 - 0.075 13.3 0.0 0.47 10.8 0.0 2.0 1 1 1 2 2 2 0 Orf78 (ac78) Phage_Gp23 PF10669.9 GAP91747.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) T2SSM PF04612.12 GAP91747.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF2207 PF09972.9 GAP91747.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKG6 PF08693.10 GAP91747.1 - 0.16 11.4 1.9 0.39 10.2 1.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.16 GAP91747.1 - 0.18 10.5 0.7 0.28 9.9 0.7 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2500 PF10694.9 GAP91747.1 - 0.22 12.1 0.0 0.37 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Syndecan PF01034.20 GAP91747.1 - 0.25 11.3 0.6 0.5 10.3 0.6 1.5 1 0 0 1 1 1 0 Syndecan domain DUF2615 PF11027.8 GAP91747.1 - 0.28 11.3 0.8 1.1 9.5 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) FYDLN_acid PF09538.10 GAP91747.1 - 0.28 11.9 13.3 0.57 10.9 6.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) O-antigen_lig PF13425.6 GAP91747.1 - 0.33 9.7 0.0 0.45 9.3 0.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein OATP PF03137.20 GAP91747.1 - 0.36 9.1 0.0 0.47 8.7 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 GAP91747.1 - 0.48 8.6 1.7 0.35 9.1 0.2 1.4 1 1 0 1 1 1 0 BT1 family DUF4834 PF16118.5 GAP91747.1 - 0.66 11.0 2.0 1.7 9.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) GCIP PF13324.6 GAP91747.1 - 0.92 9.1 2.5 1.3 8.6 2.5 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Pox_Ag35 PF03286.14 GAP91747.1 - 0.98 9.2 9.7 0.41 10.4 1.0 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 GAP91747.1 - 1.6 8.4 23.9 0.31 10.7 11.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CcmD PF04995.14 GAP91747.1 - 1.6 8.9 5.0 4.4 7.5 5.0 1.8 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) Conotoxin PF02950.17 GAP91747.1 - 1.8 9.7 4.6 2.1 9.4 0.0 2.6 2 1 0 2 2 1 0 Conotoxin Utp14 PF04615.13 GAP91747.1 - 4.4 5.8 14.7 11 4.5 14.7 1.4 1 1 0 1 1 1 0 Utp14 protein Presenilin PF01080.17 GAP91747.1 - 7.7 5.2 4.4 16 4.2 4.4 1.4 1 1 0 1 1 1 0 Presenilin TPR_14 PF13428.6 GAP91748.1 - 2.4e-05 24.8 8.2 0.15 12.9 2.9 4.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 GAP91748.1 - 6.4e-05 23.1 0.2 3.9 8.1 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAP91748.1 - 0.001 19.5 2.5 2.1 8.9 1.1 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAP91748.1 - 0.11 12.2 0.4 0.78 9.5 0.1 2.6 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 GAP91748.1 - 0.21 11.7 4.6 0.92 9.7 4.6 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DREPP PF05558.12 GAP91748.1 - 0.22 11.4 2.1 0.55 10.1 2.1 1.6 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide TPR_16 PF13432.6 GAP91748.1 - 1.1 10.0 8.8 16 6.2 3.8 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CARD_2 PF16739.5 GAP91748.1 - 1.1 9.2 3.8 24 5.0 0.3 4.3 5 0 0 5 5 5 0 Caspase recruitment domain ChAPs PF09295.10 GAP91749.1 - 5.3e-152 506.4 0.0 6.9e-152 506.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 GAP91749.1 - 6.3e-08 32.8 1.4 0.51 11.3 1.5 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP91749.1 - 2.6e-05 23.9 1.8 0.7 10.0 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAP91749.1 - 3.7e-05 24.2 1.2 0.28 11.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAP91749.1 - 8.2e-05 22.4 6.6 0.29 11.3 3.9 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAP91749.1 - 0.00057 20.0 0.4 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAP91749.1 - 0.0016 18.5 0.3 2.4 8.6 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP91749.1 - 0.0023 18.1 4.0 2.5 8.4 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 GAP91749.1 - 0.0049 17.5 0.4 4.6 8.0 0.8 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP91749.1 - 0.005 16.6 1.4 4.6 7.2 1.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 GAP91749.1 - 0.021 14.0 2.8 0.054 12.7 0.7 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 GAP91749.1 - 0.022 15.0 4.9 10 6.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAP91749.1 - 0.091 13.4 2.3 44 5.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Zn_clus PF00172.18 GAP91750.1 - 2.7e-08 33.8 10.5 4e-08 33.2 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AdoHcyase PF05221.17 GAP91751.1 - 6.5e-131 435.9 0.0 2.3e-74 250.2 0.3 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 GAP91751.1 - 4.9e-83 277.1 1.7 8.6e-83 276.3 1.7 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 GAP91751.1 - 2.8e-07 30.1 0.1 5.6e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 GAP91751.1 - 0.00073 19.1 0.2 0.0013 18.3 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 GAP91751.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 GAP91751.1 - 0.097 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain JAB PF01398.21 GAP91752.1 - 2.9e-08 33.7 0.7 1.2e-06 28.4 0.7 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DivIC PF04977.15 GAP91754.1 - 0.0052 16.5 0.2 0.0052 16.5 0.2 2.3 3 0 0 3 3 3 1 Septum formation initiator ZapB PF06005.12 GAP91754.1 - 0.011 16.2 2.9 0.074 13.5 2.9 2.3 1 1 0 1 1 1 0 Cell division protein ZapB K-box PF01486.17 GAP91754.1 - 0.084 13.1 3.0 6.8 6.9 0.1 2.9 3 0 0 3 3 3 0 K-box region BLOC1_2 PF10046.9 GAP91754.1 - 0.18 12.1 0.5 0.6 10.5 0.1 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 GAP91754.1 - 0.25 11.5 1.6 0.49 10.5 0.3 1.9 2 0 0 2 2 2 0 Tropomyosin like SlyX PF04102.12 GAP91754.1 - 0.32 11.6 10.9 0.3 11.7 0.7 3.7 3 1 1 4 4 4 0 SlyX HALZ PF02183.18 GAP91754.1 - 0.61 10.3 0.1 0.61 10.3 0.1 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 GAP91754.1 - 1.7 8.9 5.2 2.9 8.1 0.4 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Pex14_N PF04695.13 GAP91755.1 - 1.6 9.4 9.1 2.8 8.6 9.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_L10 PF00466.20 GAP91756.1 - 0.0052 16.9 0.0 0.23 11.6 0.0 2.9 3 1 0 3 3 3 1 Ribosomal protein L10 Glycos_transf_3 PF00591.21 GAP91757.1 - 3.8e-62 210.2 0.0 5.5e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 GAP91757.1 - 2.9e-10 39.8 0.0 8.1e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain tRNA_lig_CPD PF08302.11 GAP91758.1 - 1.1e-90 303.6 0.0 1.5e-90 303.1 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 GAP91758.1 - 3.6e-87 291.9 0.0 6.4e-87 291.0 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 GAP91758.1 - 2.3e-56 190.5 2.9 5.9e-55 185.9 0.6 2.4 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_18 PF13238.6 GAP91758.1 - 0.021 15.4 0.1 0.39 11.3 0.1 3.0 2 1 0 2 2 2 0 AAA domain SPOUT_MTase PF02590.17 GAP91758.1 - 0.15 12.1 0.4 0.56 10.2 0.3 2.0 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase Ribonuc_P_40 PF08584.11 GAP91759.1 - 1.7e-46 158.8 0.0 1.5e-45 155.7 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit UPF0020 PF01170.18 GAP91760.1 - 2e-08 34.2 0.0 8.7e-07 28.8 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MethyltransfD12 PF02086.15 GAP91760.1 - 0.096 12.4 0.0 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Vac_ImportDeg PF09783.9 GAP91761.1 - 8.4e-68 227.3 2.6 1e-67 227.0 2.6 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 GAP91762.1 - 4.3e-72 240.9 0.2 4.8e-72 240.7 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Beta-lactamase PF00144.24 GAP91764.1 - 2.5e-38 132.1 0.2 9.2e-38 130.3 0.2 1.7 1 1 0 1 1 1 1 Beta-lactamase FMO-like PF00743.19 GAP91765.1 - 3.2e-19 68.7 0.5 1.9e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 GAP91765.1 - 5e-16 58.8 0.0 2.7e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP91765.1 - 2.2e-09 36.9 0.0 6.3e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 GAP91765.1 - 2.8e-08 33.4 0.0 1.2e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP91765.1 - 3e-06 27.4 4.2 6.3e-06 26.3 0.1 3.4 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP91765.1 - 0.0061 16.2 0.1 0.16 11.5 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAP91765.1 - 0.012 15.6 2.3 19 5.2 0.0 4.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 GAP91765.1 - 0.022 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 GAP91765.1 - 0.026 13.6 0.1 0.11 11.6 0.1 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 GAP91765.1 - 0.032 14.8 0.2 4.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP91765.1 - 0.12 11.0 1.7 0.21 10.2 0.0 2.2 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 GAP91765.1 - 0.31 10.1 0.8 12 4.9 0.0 2.9 3 1 0 3 3 3 0 Glucose inhibited division protein A NACHT PF05729.12 GAP91766.1 - 2e-16 60.3 0.0 9.3e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain HEAT_2 PF13646.6 GAP91766.1 - 3.5e-15 56.2 9.3 4.7e-06 26.9 0.5 5.8 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 GAP91766.1 - 3.2e-06 26.9 2.7 0.018 15.2 0.1 5.4 5 0 0 5 5 5 1 HEAT repeat NLRC4_HD2 PF17776.1 GAP91766.1 - 2.1e-05 25.1 1.4 4.4e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 NLRC4 helical domain HD2 NB-ARC PF00931.22 GAP91766.1 - 6.3e-05 22.3 0.0 0.00014 21.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain HEAT_EZ PF13513.6 GAP91766.1 - 0.00088 19.7 7.1 0.023 15.2 0.3 4.3 5 0 0 5 5 4 1 HEAT-like repeat Adaptin_N PF01602.20 GAP91766.1 - 0.0037 15.9 0.4 0.52 8.8 0.0 3.0 3 0 0 3 3 3 1 Adaptin N terminal region DNA_alkylation PF08713.11 GAP91766.1 - 0.0048 16.7 0.0 4.9 6.8 0.0 3.4 2 1 0 2 2 2 1 DNA alkylation repair enzyme AAA_16 PF13191.6 GAP91766.1 - 0.005 17.2 0.0 0.056 13.8 0.0 2.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP91766.1 - 0.0088 16.3 0.2 0.19 12.0 0.1 3.3 3 1 0 3 3 2 1 AAA domain Arm PF00514.23 GAP91766.1 - 0.011 15.8 1.6 8.3 6.6 0.0 3.9 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat AAA_18 PF13238.6 GAP91766.1 - 0.02 15.4 0.2 0.22 12.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 GAP91766.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 GAP91766.1 - 0.18 12.2 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RasGEF_N_2 PF14663.6 GAP91766.1 - 0.24 11.8 3.2 79 3.7 0.0 4.5 4 1 1 5 5 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cohesin_HEAT PF12765.7 GAP91766.1 - 3.6 8.0 5.4 38 4.7 1.3 3.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion SDA1 PF05285.12 GAP91766.1 - 5.4 6.4 13.5 9.2 5.6 13.5 1.3 1 0 0 1 1 1 0 SDA1 Adaptin_N PF01602.20 GAP91768.1 - 1.2e-93 314.5 8.9 1.9e-93 313.8 8.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 GAP91768.1 - 1.4e-60 203.2 0.5 3.2e-60 202.1 0.5 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 GAP91768.1 - 9.4e-57 190.5 0.0 2.5e-56 189.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 GAP91768.1 - 3.9e-15 56.3 2.1 6.4e-11 42.6 0.0 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 GAP91768.1 - 1.6e-07 31.6 4.5 4.4e-05 23.8 0.0 4.5 3 1 1 4 4 4 1 HEAT repeats Coatomer_g_Cpla PF16381.5 GAP91768.1 - 0.00012 22.2 0.0 0.00037 20.6 0.0 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 GAP91768.1 - 0.0038 17.3 0.2 5.6 7.5 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat DUF5578 PF17741.1 GAP91768.1 - 0.022 14.2 2.6 3.6 6.9 0.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5578) AP4E_app_platf PF14807.6 GAP91768.1 - 0.038 14.3 0.3 0.13 12.6 0.3 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 GAP91768.1 - 0.18 12.4 2.2 28 5.3 0.0 4.3 4 1 1 5 5 5 0 HEAT-like repeat RskA PF10099.9 GAP91769.1 - 0.038 14.3 0.9 0.04 14.2 0.9 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Aldo_ket_red PF00248.21 GAP91770.1 - 8.4e-44 149.9 0.0 5.1e-42 144.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sacchrp_dh_NADP PF03435.18 GAP91770.1 - 0.038 14.3 0.0 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HIT PF01230.23 GAP91771.1 - 5.9e-18 65.4 0.0 8.6e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 GAP91771.1 - 4.3e-07 30.4 0.0 7.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 GAP91771.1 - 0.05 13.5 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 NOA36 PF06524.12 GAP91771.1 - 0.24 10.7 9.2 0.34 10.2 9.2 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 GAP91771.1 - 1.6 8.4 8.0 2.6 7.7 8.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 GAP91771.1 - 4.3 5.5 9.4 5.4 5.2 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 GAP91771.1 - 6.1 4.9 10.2 7.2 4.7 10.2 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_RNApol_7kD PF03604.13 GAP91772.1 - 2.3e-14 52.8 8.7 2.9e-14 52.4 8.7 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_13 PF09855.9 GAP91772.1 - 0.0036 17.4 2.7 1.6 9.0 0.5 2.2 1 1 1 2 2 2 2 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn-ribbon_8 PF09723.10 GAP91772.1 - 0.0073 16.4 1.9 0.013 15.6 1.9 1.3 1 0 0 1 1 1 1 Zinc ribbon domain HypA PF01155.19 GAP91772.1 - 0.012 15.6 0.7 0.015 15.3 0.7 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 GAP91772.1 - 0.029 13.9 2.5 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding TFIIS_C PF01096.18 GAP91772.1 - 0.03 14.2 3.0 0.38 10.7 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_ribbon_SprT PF17283.2 GAP91772.1 - 0.036 14.0 3.0 0.064 13.2 3.0 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain GFA PF04828.14 GAP91772.1 - 0.09 13.1 2.6 3.2 8.1 0.4 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf_UBZ PF18439.1 GAP91772.1 - 0.16 11.6 3.2 8.3 6.1 0.9 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 GAP91772.1 - 2.2 8.9 5.4 3.1 8.4 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 GAP91772.1 - 4.6 7.1 6.8 18 5.2 0.3 2.3 1 1 1 2 2 2 0 zinc-finger C2H2-type Rubredoxin_2 PF18073.1 GAP91772.1 - 9.4 6.1 9.0 2.4 8.0 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain ATP_bind_1 PF03029.17 GAP91773.1 - 4.2e-70 236.3 0.0 6.5e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 GAP91773.1 - 5.3e-06 25.6 0.4 0.005 15.8 0.1 2.3 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 GAP91773.1 - 1.6e-05 24.7 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 GAP91773.1 - 2.6e-05 23.9 0.0 0.0025 17.4 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 GAP91773.1 - 0.00038 20.2 0.1 0.00083 19.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 GAP91773.1 - 0.001 19.2 0.0 0.014 15.4 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 GAP91773.1 - 0.0011 18.3 0.0 0.033 13.3 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.21 GAP91773.1 - 0.0015 18.0 0.0 1.2 8.5 0.0 3.0 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 GAP91773.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 GAP91773.1 - 0.0027 17.2 0.0 0.099 12.2 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B Roc PF08477.13 GAP91773.1 - 0.0028 17.9 0.0 2.8 8.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 GAP91773.1 - 0.0037 16.5 0.1 0.0096 15.1 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 GAP91773.1 - 0.004 17.1 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 GAP91773.1 - 0.0049 17.0 0.1 0.015 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 GAP91773.1 - 0.006 16.9 0.0 0.018 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 GAP91773.1 - 0.0083 16.0 0.1 4.9 7.0 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_23 PF13476.6 GAP91773.1 - 0.012 16.1 0.0 2.1 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAP91773.1 - 0.014 14.7 0.0 0.037 13.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 GAP91773.1 - 0.019 14.6 0.0 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PRK PF00485.18 GAP91773.1 - 0.02 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 GAP91773.1 - 0.02 14.5 0.0 0.73 9.4 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 GAP91773.1 - 0.033 13.7 0.0 0.088 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 GAP91773.1 - 0.082 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 GAP91773.1 - 0.14 11.9 0.1 1.3 8.7 0.0 2.5 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF1168 PF06658.12 GAP91773.1 - 0.16 11.7 5.7 0.32 10.8 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) BTB PF00651.31 GAP91774.1 - 5.8e-08 32.9 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 GAP91774.1 - 0.048 13.8 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Pkinase_fungal PF17667.1 GAP91775.1 - 4.1e-129 430.9 0.0 4.9e-129 430.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 GAP91775.1 - 9e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 GAP91775.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hydrolase_4 PF12146.8 GAP91777.1 - 6.3e-07 28.9 0.0 1.6e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAP91777.1 - 1.6e-06 27.8 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAP91777.1 - 1e-05 26.2 0.0 1.2e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP91777.1 - 1.7e-05 24.6 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 GAP91777.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 GAP91777.1 - 0.00014 20.6 0.1 0.00023 19.9 0.1 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 GAP91777.1 - 0.00079 19.4 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 GAP91777.1 - 0.0059 16.2 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family COX7a PF02238.15 GAP91777.1 - 0.044 14.2 1.2 1.5 9.3 0.2 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII p450 PF00067.22 GAP91778.1 - 3.2e-52 177.8 0.0 4.1e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DIOX_N PF14226.6 GAP91779.1 - 7.9e-12 46.0 0.0 1.6e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP91779.1 - 5.5e-11 42.8 0.0 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 GAP91780.1 - 7.2e-25 88.0 0.0 1.3e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP91780.1 - 7.5e-18 64.9 0.0 1.4e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NB-ARC PF00931.22 GAP91783.1 - 1.2e-10 41.0 0.0 2.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.14 GAP91783.1 - 3.9e-07 29.8 0.0 7.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 GAP91783.1 - 4.2e-07 30.5 0.0 1.4e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TPR_12 PF13424.6 GAP91783.1 - 6.1e-06 26.4 0.4 0.006 16.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 GAP91783.1 - 0.00069 20.3 0.2 0.0018 18.9 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.12 GAP91783.1 - 0.00078 19.4 0.1 0.0047 16.8 0.0 2.4 2 1 0 2 2 2 1 NACHT domain PGAP1 PF07819.13 GAP91783.1 - 0.0013 18.5 0.0 0.0036 17.0 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 GAP91783.1 - 0.0018 17.6 0.0 0.0036 16.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF829 PF05705.14 GAP91783.1 - 0.0026 17.7 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) ANAPC3 PF12895.7 GAP91783.1 - 0.0027 17.9 5.5 4.6 7.5 0.0 3.6 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 GAP91783.1 - 0.0049 16.7 0.0 0.58 10.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAP91783.1 - 0.04 14.0 0.0 66 3.9 0.0 4.4 5 1 0 5 5 3 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 GAP91783.1 - 0.047 13.4 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 GAP91783.1 - 0.051 13.8 0.0 0.27 11.5 0.0 2.2 3 0 0 3 3 2 0 AAA domain TPR_19 PF14559.6 GAP91783.1 - 0.094 13.2 6.8 0.96 10.0 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat ArsA_ATPase PF02374.15 GAP91783.1 - 0.15 11.2 0.1 0.25 10.5 0.1 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase Cutinase PF01083.22 GAP91783.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Cutinase Torsin PF06309.11 GAP91783.1 - 0.16 12.0 0.1 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 Torsin TPR_2 PF07719.17 GAP91783.1 - 0.21 11.8 6.1 1.2 9.5 0.1 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 GAP91783.1 - 0.84 9.6 3.6 10 6.1 0.2 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Peptidase_S24 PF00717.23 GAP91784.1 - 4.1e-06 26.7 0.0 8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like TFIIB PF00382.19 GAP91785.1 - 4e-24 84.4 0.1 3.8e-18 65.3 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 GAP91785.1 - 7.9e-23 80.7 4.2 3.1e-22 78.8 1.0 2.8 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 GAP91785.1 - 0.011 15.5 0.3 2.3 8.0 0.0 2.4 1 1 1 2 2 2 0 Cyclin, N-terminal domain zf-A20 PF01754.16 GAP91785.1 - 0.17 11.9 1.7 0.3 11.1 1.7 1.4 1 0 0 1 1 1 0 A20-like zinc finger CwfJ_C_1 PF04677.15 GAP91786.1 - 9.3e-31 106.2 0.0 1.8e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 GAP91786.1 - 1.6e-27 96.3 0.1 6.9e-27 94.2 0.1 2.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Brix PF04427.18 GAP91787.1 - 4e-42 144.5 0.0 5.2e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF1765 PF08578.10 GAP91788.1 - 8.8e-42 142.5 9.6 1.6e-41 141.7 9.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) MFS_1 PF07690.16 GAP91789.1 - 4.7e-26 91.5 51.3 1.4e-25 90.0 30.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 GAP91790.1 - 6.3e-08 32.6 10.1 1e-07 31.9 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAP91790.1 - 0.0029 16.5 0.6 0.0046 15.8 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TMEM239 PF15841.5 GAP91790.1 - 0.081 12.8 3.6 0.29 11.0 0.7 2.3 2 0 0 2 2 2 0 Transmembrane protein 239 family Glyco_hydro_92 PF07971.12 GAP91791.1 - 6.9e-141 470.3 1.7 8.5e-141 470.0 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAP91791.1 - 1.5e-64 218.2 0.8 2.6e-64 217.4 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain DPBB_1 PF03330.18 GAP91792.1 - 6.3e-10 39.2 0.2 8.9e-10 38.7 0.2 1.3 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 GAP91792.1 - 2.5e-05 24.1 0.1 3e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 GAP91792.1 - 0.0023 18.1 0.1 0.0052 16.9 0.0 1.4 1 1 0 1 1 1 1 Cerato-platanin Lipocalin_5 PF13924.6 GAP91793.1 - 1.1e-09 38.2 0.0 1.3e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain HSNSD PF12062.8 GAP91793.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase Glyco_hydro_3_C PF01915.22 GAP91794.1 - 1.2e-42 146.2 0.3 1.9e-42 145.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAP91794.1 - 3.7e-33 115.3 0.0 5.7e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAP91794.1 - 0.0067 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_4 PF01565.23 GAP91795.1 - 2.8e-23 82.2 0.4 6.6e-23 81.0 0.4 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP91795.1 - 1.7e-10 40.9 0.1 3.5e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans_2 PF11951.8 GAP91797.1 - 6.5e-06 25.2 1.3 6.5e-06 25.2 1.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP91797.1 - 7.1e-06 26.0 9.4 1.2e-05 25.4 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3_C PF01915.22 GAP91798.1 - 1.4e-46 159.1 0.0 3.2e-46 157.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 GAP91798.1 - 1.2e-37 130.0 0.0 2.1e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 GAP91798.1 - 1.6e-19 69.8 0.0 3e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_4 PF01565.23 GAP91799.1 - 8.5e-24 83.9 3.0 1.8e-23 82.8 3.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP91799.1 - 8.5e-08 32.2 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like DUF1996 PF09362.10 GAP91800.1 - 2.6e-57 194.5 4.5 2.4e-45 155.4 0.5 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) Phosphodiest PF01663.22 GAP91802.1 - 1.8e-95 320.5 0.5 2.6e-95 320.0 0.5 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 GAP91802.1 - 0.0005 19.6 0.0 0.015 14.7 0.0 2.2 2 0 0 2 2 2 1 Sulfatase DUF3511 PF12023.8 GAP91802.1 - 0.019 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) PglZ PF08665.12 GAP91802.1 - 0.022 14.8 0.1 0.091 12.8 0.0 1.9 2 0 0 2 2 2 0 PglZ domain CCDC53 PF10152.9 GAP91802.1 - 0.024 15.1 1.0 0.08 13.4 1.0 1.8 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF5345 PF17280.2 GAP91802.1 - 0.83 9.7 2.8 3.5 7.7 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Lipase_2 PF01674.18 GAP91803.1 - 4.9e-10 39.3 0.0 6.9e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 2) Abhydrolase_6 PF12697.7 GAP91803.1 - 0.00023 21.8 10.1 0.00036 21.2 10.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP91803.1 - 0.0039 16.5 0.6 0.0061 15.9 0.6 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 GAP91803.1 - 0.0042 17.0 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 GAP91803.1 - 0.0059 16.1 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DAGAT PF03982.13 GAP91803.1 - 0.15 11.0 0.0 0.29 10.0 0.0 1.4 1 1 0 1 1 1 0 Diacylglycerol acyltransferase DUF1773 PF08593.10 GAP91804.1 - 0.018 16.0 0.0 0.055 14.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function Pec_lyase_C PF00544.19 GAP91805.1 - 3.7e-13 49.5 9.4 2.9e-11 43.4 9.4 2.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 GAP91805.1 - 4.6e-05 23.3 8.9 0.044 13.6 4.5 2.3 1 1 1 2 2 2 2 Right handed beta helix region HKR_ArcB_TM PF18415.1 GAP91807.1 - 5.8 7.8 9.3 1.3 9.9 2.9 2.7 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain FAD_binding_4 PF01565.23 GAP91808.1 - 7.9e-16 58.1 4.5 8e-09 35.4 0.1 2.6 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.12 GAP91808.1 - 1.1e-09 38.2 0.1 2.5e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like E1-E2_ATPase PF00122.20 GAP91810.1 - 1.3e-32 112.8 12.3 8.9e-24 84.0 0.2 3.9 4 0 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 GAP91810.1 - 1.5e-18 67.9 0.0 5.3e-18 66.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 GAP91810.1 - 1.5e-09 37.4 0.0 3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 GAP91810.1 - 0.0039 17.0 0.1 0.0083 15.9 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GNVR PF13807.6 GAP91810.1 - 0.066 13.1 0.7 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Cation_ATPase PF13246.6 GAP91810.1 - 0.092 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) adh_short_C2 PF13561.6 GAP91811.1 - 7.1e-52 176.3 0.1 1e-51 175.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP91811.1 - 5.1e-37 127.2 0.7 7.7e-37 126.6 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP91811.1 - 5.4e-12 46.0 0.3 8.3e-12 45.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Catalase-rel PF06628.12 GAP91812.1 - 0.019 15.2 0.1 0.04 14.1 0.1 1.4 1 0 0 1 1 1 0 Catalase-related immune-responsive CNDH2_C PF16858.5 GAP91813.1 - 0.098 12.5 4.6 0.16 11.8 4.6 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF3245 PF11595.8 GAP91813.1 - 0.32 11.5 5.2 0.65 10.5 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) PHD PF00628.29 GAP91814.1 - 1.7e-10 40.6 2.7 4.3e-10 39.3 2.7 1.7 1 0 0 1 1 1 1 PHD-finger UIM PF02809.20 GAP91814.1 - 0.024 14.5 0.9 0.024 14.5 0.9 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif PHD_2 PF13831.6 GAP91814.1 - 0.025 14.1 2.4 0.042 13.4 2.4 1.4 1 0 0 1 1 1 0 PHD-finger CEBP_ZZ PF16366.5 GAP91814.1 - 4.4 7.6 5.8 15 5.9 5.9 1.7 1 1 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain MMR_HSR1 PF01926.23 GAP91815.1 - 4.5e-11 42.8 0.0 9.2e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAP91815.1 - 0.00083 19.5 0.1 0.11 12.5 0.0 2.3 2 0 0 2 2 2 1 Dynamin family IIGP PF05049.13 GAP91815.1 - 0.02 14.0 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 GAP91815.1 - 0.022 14.3 0.5 0.046 13.3 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 GAP91815.1 - 0.027 14.9 0.1 0.08 13.3 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 GAP91815.1 - 0.063 13.8 0.1 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 GAP91815.1 - 0.087 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAP91815.1 - 0.12 12.2 0.2 0.4 10.6 0.2 1.9 1 1 0 1 1 1 0 RsgA GTPase Arf PF00025.21 GAP91815.1 - 0.18 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family adh_short PF00106.25 GAP91816.1 - 7.4e-28 97.3 0.0 1e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP91816.1 - 5.6e-20 71.9 0.0 8.8e-19 68.0 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HicA_toxin PF07927.12 GAP91817.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, HET PF06985.11 GAP91820.1 - 3.5e-10 40.4 4.8 8.6e-08 32.6 0.5 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 GAP91821.1 - 5.5e-14 52.1 0.0 9.4e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP91821.1 - 6.2e-08 32.5 0.0 8.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 GAP91821.1 - 0.0053 16.3 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Pkinase PF00069.25 GAP91823.1 - 9e-14 51.5 0.0 1.4e-12 47.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 GAP91824.1 - 1e-15 57.8 0.0 3.2e-15 56.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP91824.1 - 8.1e-07 28.6 0.0 2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 GAP91824.1 - 0.0047 16.0 0.0 0.0071 15.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Prok-RING_2 PF14445.6 GAP91824.1 - 0.052 13.7 0.0 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Choline_kinase PF01633.20 GAP91824.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATP-synt_ab_N PF02874.23 GAP91825.1 - 0.072 13.6 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain AflR PF08493.10 GAP91827.1 - 1.2e-10 41.4 0.1 1.6e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Pkinase PF00069.25 GAP91828.1 - 1.7e-53 181.7 1.5 1.9e-33 115.9 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP91828.1 - 2.9e-36 125.1 0.0 9.4e-26 90.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 GAP91828.1 - 0.00019 20.9 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 GAP91828.1 - 0.21 11.5 1.2 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Hamartin PF04388.12 GAP91829.1 - 0.0083 14.9 14.8 0.01 14.5 14.8 1.2 1 0 0 1 1 1 1 Hamartin protein SKG6 PF08693.10 GAP91829.1 - 0.043 13.2 1.4 0.043 13.2 1.4 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Mid2 PF04478.12 GAP91829.1 - 0.046 13.6 0.3 0.046 13.6 0.3 2.6 1 1 2 3 3 3 0 Mid2 like cell wall stress sensor Ndc1_Nup PF09531.10 GAP91829.1 - 0.097 11.3 5.5 0.12 11.1 5.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4265 PF14085.6 GAP91832.1 - 1.3 9.0 5.1 0.87 9.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4265) Cerato-platanin PF07249.12 GAP91833.1 - 7.3e-58 193.9 2.4 8.4e-58 193.7 2.4 1.0 1 0 0 1 1 1 1 Cerato-platanin RHS_repeat PF05593.14 GAP91833.1 - 0.00079 19.9 2.6 0.0051 17.3 0.1 2.9 3 0 0 3 3 3 1 RHS Repeat Peptidase_M64 PF09471.10 GAP91834.1 - 1.3e-26 93.7 0.0 7.4e-26 91.2 0.0 1.9 1 1 0 1 1 1 1 IgA Peptidase M64 2-Hacid_dh_C PF02826.19 GAP91835.1 - 8.8e-53 178.3 0.0 1.3e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP91835.1 - 8e-30 103.2 0.1 1.1e-29 102.8 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAP91835.1 - 0.00017 21.8 0.0 0.00061 20.0 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 GAP91835.1 - 0.0016 18.6 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 GAP91835.1 - 0.036 13.6 0.0 0.094 12.3 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 GAP91835.1 - 0.041 14.4 0.1 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain DUF1045 PF06299.12 GAP91835.1 - 0.064 13.2 0.3 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) Peripla_BP_3 PF13377.6 GAP91835.1 - 0.11 12.8 0.4 0.3 11.4 0.2 1.8 2 0 0 2 2 2 0 Periplasmic binding protein-like domain ANF_receptor PF01094.28 GAP91835.1 - 0.21 10.6 0.0 1.8 7.6 0.0 2.0 2 0 0 2 2 2 0 Receptor family ligand binding region MatE PF01554.18 GAP91836.1 - 9.6e-54 181.4 30.2 1.6e-32 112.4 14.1 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 GAP91836.1 - 9.3e-05 22.5 4.2 9.3e-05 22.5 4.2 4.1 2 1 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 GAP91836.1 - 0.00012 20.9 6.0 0.00012 20.9 6.0 1.8 1 1 0 1 1 1 1 Lipid II flippase MurJ Como_SCP PF02248.16 GAP91836.1 - 0.059 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Small coat protein Aldo_ket_red PF00248.21 GAP91837.1 - 1e-32 113.5 0.0 1.8e-25 89.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DUF1967 PF09269.11 GAP91837.1 - 0.17 11.9 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Wzy_C PF04932.15 GAP91839.1 - 0.15 11.7 1.5 0.51 10.0 1.9 1.5 1 1 0 1 1 1 0 O-Antigen ligase NRBF2 PF08961.10 GAP91839.1 - 6 6.4 5.4 11 5.5 5.4 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator fn3_2 PF16893.5 GAP91841.1 - 2.8e-38 129.9 0.1 4.6e-38 129.2 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 GAP91841.1 - 9e-23 80.0 1.0 1.5e-22 79.3 1.0 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 GAP91841.1 - 5.4e-13 48.7 0.0 1.1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 GAP91841.1 - 4e-12 46.3 0.0 7.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 GAP91841.1 - 7e-05 23.2 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 GAP91841.1 - 0.0021 18.4 0.0 0.0073 16.6 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.8 GAP91841.1 - 0.015 15.5 0.4 0.06 13.6 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3006) GEMIN8 PF15348.6 GAP91841.1 - 0.19 12.0 5.1 0.29 11.4 5.1 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 eIF-1a PF01176.19 GAP91843.1 - 1.8e-21 75.7 0.0 2.6e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.23 GAP91844.1 - 1.8e-26 92.2 0.2 2.7e-26 91.7 0.2 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 GAP91844.1 - 0.00025 20.8 0.2 0.00052 19.8 0.2 1.5 1 0 0 1 1 1 1 WH2 motif DUF2076 PF09849.9 GAP91844.1 - 0.0014 18.8 0.5 0.0014 18.8 0.5 4.7 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) ERCC4 PF02732.15 GAP91846.1 - 1.2e-20 74.2 0.0 2.7e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain zf-C2H2_2 PF12756.7 GAP91847.1 - 0.068 13.5 0.0 0.085 13.2 0.0 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Melibiase PF02065.18 GAP91849.1 - 8.2e-130 432.8 0.0 1e-129 432.5 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 GAP91849.1 - 1.3e-72 244.5 0.1 1.9e-72 243.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 GAP91849.1 - 1.2e-19 70.6 0.0 2.2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 GAP91849.1 - 0.0018 17.4 0.0 0.0049 16.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase-like 10 ThrE PF06738.12 GAP91851.1 - 1.1e-68 231.2 17.6 2.1e-65 220.5 2.9 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 GAP91851.1 - 3e-11 43.5 10.1 3e-11 43.5 10.1 2.4 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE DUF2651 PF10852.8 GAP91851.1 - 0.013 16.1 1.6 0.047 14.3 1.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) adh_short PF00106.25 GAP91852.1 - 4.4e-30 104.6 0.0 1.2e-29 103.2 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP91852.1 - 2.8e-17 63.0 0.4 2.2e-16 60.1 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP91852.1 - 8.2e-08 32.4 1.3 2.2e-05 24.4 0.0 2.5 1 1 1 2 2 2 2 KR domain Epimerase PF01370.21 GAP91852.1 - 1.1e-05 25.1 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP91852.1 - 0.0017 18.3 0.1 0.0039 17.1 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 GAP91852.1 - 0.064 12.3 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 GAP91852.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 GAP91852.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Perilipin PF03036.16 GAP91853.1 - 0.0037 16.4 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Perilipin family Reo_P9 PF06043.11 GAP91853.1 - 0.056 12.9 0.1 0.073 12.5 0.1 1.1 1 0 0 1 1 1 0 Reovirus P9-like family Dodecin PF07311.12 GAP91853.1 - 0.068 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Dodecin PET10 PF17316.2 GAP91853.1 - 0.081 12.4 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 Petite colonies protein 10 DUF2457 PF10446.9 GAP91854.1 - 0.00075 18.8 6.1 0.00075 18.8 6.1 3.4 3 1 0 3 3 3 2 Protein of unknown function (DUF2457) Orthopox_B11R PF07033.11 GAP91855.1 - 0.081 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Orthopoxvirus B11R protein Pro_isomerase PF00160.21 GAP91856.1 - 2.1e-43 148.3 0.0 2.4e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 GAP91857.1 - 1.2e-11 45.2 0.6 4.5e-11 43.3 0.1 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.7 GAP91858.1 - 1.3e-21 76.5 0.1 2.9e-21 75.4 0.1 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term XAP5 PF04921.14 GAP91859.1 - 1.5e-85 287.0 0.0 2.5e-85 286.3 0.0 1.2 1 1 0 1 1 1 1 XAP5, circadian clock regulator DUF4551 PF15087.6 GAP91859.1 - 2.8 6.7 7.3 4.1 6.1 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF2613 PF11021.8 GAP91860.1 - 0.11 12.6 0.5 5.8 7.1 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) Tecti-min-caps PF09300.10 GAP91861.1 - 2.3 8.3 6.0 7 6.8 5.1 2.3 2 1 0 2 2 2 0 Tectiviridae, minor capsid Fip1 PF05182.13 GAP91862.1 - 5.1e-20 70.7 0.9 9.6e-20 69.8 0.9 1.5 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.6 GAP91863.1 - 1.3e-10 41.9 78.3 1.1e-09 39.1 29.7 3.7 2 1 1 3 3 3 2 Nucleoporin FG repeat region DUF3584 PF12128.8 GAP91863.1 - 0.025 12.1 1.6 0.055 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 GAP91863.1 - 0.05 13.8 0.2 0.98 9.6 0.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Lipoprotein_2 PF00921.17 GAP91863.1 - 0.17 11.5 0.3 0.67 9.5 0.0 2.0 2 0 0 2 2 2 0 Borrelia lipoprotein DUF948 PF06103.11 GAP91863.1 - 0.25 11.6 1.0 11 6.4 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 GAP91863.1 - 0.32 8.9 0.3 1.2 7.0 0.1 1.6 1 1 0 1 1 1 0 Prominin TFIIA PF03153.13 GAP91863.1 - 9.3 6.1 28.5 23 4.8 28.5 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 GAP91864.1 - 0.0047 17.0 29.3 0.0067 16.5 29.3 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Fungal_trans_2 PF11951.8 GAP91865.1 - 7.1e-05 21.8 0.6 0.00013 20.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP91865.1 - 0.0078 16.3 4.9 0.017 15.2 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP91867.1 - 1.9e-11 43.5 0.0 3.3e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP91867.1 - 2.1e-05 24.6 8.3 4e-05 23.7 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_10 PF05971.12 GAP91868.1 - 1.1e-59 202.2 0.0 1.6e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 GAP91868.1 - 1.2e-07 31.4 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 GAP91868.1 - 0.00067 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 GAP91868.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP91868.1 - 0.0043 17.7 0.0 0.01 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 GAP91868.1 - 0.029 14.3 0.0 0.089 12.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 GAP91868.1 - 0.068 13.9 0.0 0.16 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 GAP91868.1 - 0.076 13.7 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Herpes_LMP1 PF05297.11 GAP91868.1 - 0.18 10.9 0.3 0.26 10.5 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SNO PF01174.19 GAP91869.1 - 2.7e-54 183.9 0.0 3.3e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 GAP91869.1 - 1.2e-10 41.3 0.0 6.4e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 GAP91869.1 - 0.0054 16.5 0.0 0.0083 15.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 GAP91869.1 - 0.0063 16.2 0.0 0.015 14.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase family S51 SOR_SNZ PF01680.17 GAP91870.1 - 8.7e-103 342.5 5.6 1.1e-102 342.1 5.6 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 GAP91870.1 - 6e-08 32.3 9.4 4.5e-06 26.2 0.3 2.8 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 GAP91870.1 - 6.2e-05 23.0 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 GAP91870.1 - 0.00026 20.5 0.1 0.017 14.6 0.0 2.9 2 1 1 3 3 3 1 Histidine biosynthesis protein NanE PF04131.14 GAP91870.1 - 0.0019 17.5 1.0 0.031 13.5 0.0 2.7 2 1 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.17 GAP91870.1 - 0.0019 17.4 0.2 0.63 9.1 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Chaperone_III PF07824.12 GAP91870.1 - 0.059 13.6 0.1 0.45 10.7 0.1 2.1 2 0 0 2 2 2 0 Type III secretion chaperone domain IGPS PF00218.21 GAP91870.1 - 0.096 11.8 0.1 1 8.5 0.0 2.3 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.15 GAP91870.1 - 3.6 6.9 11.9 0.063 12.7 2.8 2.2 2 1 0 2 2 2 0 Nitronate monooxygenase Lipase_GDSL_2 PF13472.6 GAP91871.1 - 4.6e-09 36.9 0.5 9.8e-09 35.9 0.5 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP91871.1 - 0.00073 19.6 0.3 0.002 18.1 0.3 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PLDc_2 PF13091.6 GAP91872.1 - 1e-17 64.2 0.2 6.2e-07 29.4 0.0 4.4 4 0 0 4 4 4 3 PLD-like domain PLDc PF00614.22 GAP91872.1 - 3.1e-16 58.8 0.8 2.6e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF2992 PF11208.8 GAP91872.1 - 0.021 15.1 4.3 0.1 12.8 4.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) GLTP PF08718.11 GAP91873.1 - 2.2e-45 154.6 0.0 3.3e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Glyco_hydro_61 PF03443.14 GAP91875.1 - 9.9e-62 208.5 0.4 1.2e-61 208.2 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1772 PF08592.11 GAP91876.1 - 2.4e-24 86.2 9.6 3.2e-24 85.8 9.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ATPase_gene1 PF09527.10 GAP91876.1 - 0.17 12.1 0.4 0.17 12.1 0.4 2.0 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Beta-lactamase PF00144.24 GAP91877.1 - 1.2e-29 103.6 0.0 2.2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Acyltransferase PF01553.21 GAP91878.1 - 1.9e-16 59.9 0.0 4.7e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase DHHC PF01529.20 GAP91878.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase UPF0086 PF01868.16 GAP91879.1 - 1.4e-29 101.8 0.0 2.1e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Fungal_trans_2 PF11951.8 GAP91880.1 - 6.7e-10 38.3 0.4 1.5e-09 37.1 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP91880.1 - 1.2e-06 28.5 13.1 1.2e-06 28.5 13.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VF530 PF09905.9 GAP91880.1 - 0.11 12.7 0.2 5.5 7.2 0.0 2.4 2 0 0 2 2 2 0 DNA-binding protein VF530 WD40 PF00400.32 GAP91881.1 - 6.3e-15 55.3 5.2 0.012 16.5 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP91881.1 - 5.7e-05 23.3 0.1 4.1 7.8 0.0 4.3 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain HAD_2 PF13419.6 GAP91882.1 - 8.6e-07 29.2 0.0 0.0017 18.5 0.0 2.2 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP91882.1 - 0.0029 17.7 0.0 0.0061 16.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 GAP91882.1 - 0.02 15.2 0.0 0.029 14.7 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Metallophos PF00149.28 GAP91883.1 - 4.7e-11 43.6 0.0 6.4e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAP91883.1 - 2.9e-07 30.8 0.0 9.7e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1664 PF07889.12 GAP91884.1 - 1.3e-19 70.4 50.7 4.7e-08 33.1 8.5 4.9 1 1 5 6 6 6 5 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 GAP91884.1 - 2e-11 44.1 20.8 6.7e-08 32.7 8.0 2.9 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 GAP91884.1 - 2.4e-10 40.6 25.2 2.4e-06 27.6 1.5 4.0 1 1 3 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.20 GAP91884.1 - 5.4e-09 36.0 35.7 0.0051 16.7 0.9 5.6 2 1 2 5 5 5 4 Prefoldin subunit IFT57 PF10498.9 GAP91884.1 - 7.2e-09 35.1 23.4 3.4e-06 26.3 10.5 2.2 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Apolipoprotein PF01442.18 GAP91884.1 - 1.7e-08 34.6 19.8 6.6e-06 26.1 19.4 2.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Golgin_A5 PF09787.9 GAP91884.1 - 9.4e-08 31.9 23.3 0.00087 18.8 7.7 2.2 1 1 1 2 2 2 2 Golgin subfamily A member 5 CCDC144C PF14915.6 GAP91884.1 - 1.5e-07 30.8 21.0 4.4e-05 22.8 7.8 2.5 1 1 1 2 2 2 2 CCDC144C protein coiled-coil region Filament PF00038.21 GAP91884.1 - 2e-07 30.9 19.1 0.0011 18.6 2.1 2.4 1 1 1 2 2 2 2 Intermediate filament protein EzrA PF06160.12 GAP91884.1 - 3.2e-07 28.9 22.0 0.0005 18.4 12.8 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA Leu_zip PF15294.6 GAP91884.1 - 3.6e-07 30.0 28.0 0.00047 19.8 13.3 2.7 1 1 1 2 2 2 2 Leucine zipper ApoLp-III PF07464.11 GAP91884.1 - 4.1e-07 30.2 32.1 6.7e-05 23.0 18.5 3.2 1 1 2 3 3 3 3 Apolipophorin-III precursor (apoLp-III) Lebercilin PF15619.6 GAP91884.1 - 5.5e-07 29.4 23.3 0.0022 17.7 2.4 3.5 1 1 2 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease Prominin PF05478.11 GAP91884.1 - 5.7e-07 27.9 22.7 1.2e-06 26.8 22.8 1.4 1 1 0 1 1 1 1 Prominin MIP-T3_C PF17749.1 GAP91884.1 - 5.8e-07 29.6 18.0 0.0036 17.3 2.6 3.2 1 1 1 2 2 2 2 Microtubule-binding protein MIP-T3 C-terminal region FH2 PF02181.23 GAP91884.1 - 8.1e-07 28.5 18.3 0.00074 18.7 7.4 2.3 1 1 1 2 2 2 2 Formin Homology 2 Domain AAA_13 PF13166.6 GAP91884.1 - 1.4e-06 27.3 33.0 4.6e-06 25.6 18.7 1.9 1 1 1 2 2 2 2 AAA domain ApoO PF09769.9 GAP91884.1 - 1.6e-06 28.1 8.6 0.38 10.7 0.3 4.6 1 1 4 5 5 4 3 Apolipoprotein O DUF812 PF05667.11 GAP91884.1 - 3.9e-06 26.1 22.1 5.2e-06 25.6 22.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CdvA PF18822.1 GAP91884.1 - 4.3e-06 26.6 28.4 0.21 11.4 1.4 5.0 1 1 4 5 5 5 3 CdvA-like coiled-coil domain Spc7 PF08317.11 GAP91884.1 - 6e-06 25.4 29.3 0.00039 19.4 13.5 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF3606 PF12244.8 GAP91884.1 - 7e-06 25.9 3.3 0.2 11.6 0.1 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF3606) Rab5-bind PF09311.11 GAP91884.1 - 2e-05 24.1 9.2 2e-05 24.1 9.2 2.9 1 1 1 2 2 2 1 Rabaptin-like protein HMMR_N PF15905.5 GAP91884.1 - 2.2e-05 24.1 31.1 0.00093 18.8 13.3 2.2 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor N-terminal COG2 PF06148.11 GAP91884.1 - 2.5e-05 24.4 24.5 0.061 13.4 7.3 4.4 1 1 2 4 4 3 2 COG (conserved oligomeric Golgi) complex component, COG2 KxDL PF10241.9 GAP91884.1 - 3.1e-05 24.2 16.1 0.023 15.0 0.7 4.4 1 1 3 4 4 3 2 Uncharacterized conserved protein ADIP PF11559.8 GAP91884.1 - 3.7e-05 23.9 25.2 0.029 14.4 13.4 3.4 1 1 3 4 4 4 4 Afadin- and alpha -actinin-Binding HAP1_N PF04849.13 GAP91884.1 - 3.8e-05 23.0 18.4 5.9e-05 22.4 18.4 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Laminin_II PF06009.12 GAP91884.1 - 4e-05 23.7 30.7 0.067 13.2 4.5 4.4 1 1 3 4 4 4 3 Laminin Domain II DUF3584 PF12128.8 GAP91884.1 - 7.3e-05 20.5 23.7 0.00011 20.0 17.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3584) FliJ PF02050.16 GAP91884.1 - 8.2e-05 22.8 3.2 0.27 11.5 0.6 3.2 1 1 2 3 3 3 1 Flagellar FliJ protein DUF148 PF02520.17 GAP91884.1 - 9.5e-05 22.5 24.6 0.05 13.7 3.6 4.5 1 1 4 5 5 5 2 Domain of unknown function DUF148 Fib_alpha PF08702.10 GAP91884.1 - 0.0001 22.5 29.1 0.0013 18.9 4.1 3.4 1 1 2 3 3 3 1 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 GAP91884.1 - 0.00013 22.2 21.5 0.082 13.1 2.8 3.4 1 1 2 3 3 3 2 JNK_SAPK-associated protein-1 DUF2959 PF11172.8 GAP91884.1 - 0.00014 22.1 14.0 0.038 14.1 11.6 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2959) HIP1_clath_bdg PF16515.5 GAP91884.1 - 0.00015 22.3 24.5 0.048 14.3 5.8 4.0 1 1 3 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 JIP_LZII PF16471.5 GAP91884.1 - 0.00016 21.8 28.8 0.011 15.9 2.9 5.1 3 1 2 5 5 4 2 JNK-interacting protein leucine zipper II LXG PF04740.12 GAP91884.1 - 0.0003 20.6 22.3 0.002 17.9 10.2 2.6 1 1 0 2 2 2 1 LXG domain of WXG superfamily SesA PF17107.5 GAP91884.1 - 0.00043 20.5 16.1 0.085 13.1 5.9 3.8 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Tektin PF03148.14 GAP91884.1 - 0.00048 19.0 23.3 0.22 10.2 13.6 2.5 1 1 1 2 2 2 2 Tektin family ATG_C PF09333.11 GAP91884.1 - 0.00052 20.3 4.7 12 6.3 0.1 5.1 1 1 2 3 3 3 0 Autophagy-related protein C terminal domain WEMBL PF05701.11 GAP91884.1 - 0.0006 18.6 27.7 0.0056 15.4 16.1 2.0 1 1 1 2 2 2 2 Weak chloroplast movement under blue light NPV_P10 PF05531.12 GAP91884.1 - 0.00061 20.2 37.2 0.36 11.3 5.3 5.2 1 1 4 5 5 5 3 Nucleopolyhedrovirus P10 protein DLP_helical PF18709.1 GAP91884.1 - 0.00083 18.7 22.5 0.062 12.5 5.7 3.4 1 1 1 2 2 2 1 Dynamin-like helical domain TMPIT PF07851.13 GAP91884.1 - 0.00084 18.7 21.9 0.11 11.8 6.8 3.1 1 1 2 3 3 3 2 TMPIT-like protein CALCOCO1 PF07888.11 GAP91884.1 - 0.00088 18.3 21.4 0.00088 18.3 21.4 1.5 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like MSP1b PF03429.13 GAP91884.1 - 0.00093 17.4 3.7 1.2 7.1 0.4 3.3 1 1 2 3 3 3 0 Major surface protein 1B Tup_N PF08581.10 GAP91884.1 - 0.001 19.3 14.3 0.052 13.9 1.9 4.2 1 1 2 4 4 3 1 Tup N-terminal Syntaxin PF00804.25 GAP91884.1 - 0.001 18.8 24.6 0.0083 15.8 6.9 3.3 1 1 2 3 3 3 3 Syntaxin AIP3 PF03915.13 GAP91884.1 - 0.001 18.2 32.1 0.071 12.2 12.2 2.2 1 1 1 2 2 2 2 Actin interacting protein 3 FlxA PF14282.6 GAP91884.1 - 0.0011 18.9 31.2 0.11 12.5 2.0 4.7 1 1 4 5 5 4 2 FlxA-like protein Exonuc_VII_L PF02601.15 GAP91884.1 - 0.0015 18.2 15.1 1.2 8.6 15.1 2.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit LPP PF04728.13 GAP91884.1 - 0.0015 18.9 33.4 0.86 10.0 0.4 7.8 1 1 6 7 7 7 1 Lipoprotein leucine-zipper DUF745 PF05335.13 GAP91884.1 - 0.0016 18.2 13.4 0.07 12.9 3.4 2.8 1 1 2 3 3 3 2 Protein of unknown function (DUF745) GAS PF13851.6 GAP91884.1 - 0.002 17.5 23.8 0.059 12.7 9.7 2.4 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 GAP91884.1 - 0.0023 18.4 24.5 3.2 8.4 2.5 4.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal APG17 PF04108.12 GAP91884.1 - 0.0024 17.0 22.5 0.031 13.4 1.9 3.2 1 1 1 2 2 2 1 Autophagy protein Apg17 CCDC-167 PF15188.6 GAP91884.1 - 0.0025 18.1 20.9 0.39 11.1 3.7 4.1 1 1 2 3 3 3 1 Coiled-coil domain-containing protein 167 AAA_32 PF13654.6 GAP91884.1 - 0.0035 16.2 19.1 0.053 12.3 1.1 3.0 1 1 2 3 3 3 1 AAA domain KELK PF15796.5 GAP91884.1 - 0.0035 17.7 21.6 0.088 13.3 2.6 4.5 1 1 3 4 4 4 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF948 PF06103.11 GAP91884.1 - 0.0038 17.5 29.2 2.8 8.3 2.3 5.2 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 GAP91884.1 - 0.0038 16.4 25.0 0.1 11.7 13.5 2.1 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 Occludin_ELL PF07303.13 GAP91884.1 - 0.0038 17.9 10.4 3 8.6 0.3 4.4 1 1 2 4 4 4 0 Occludin homology domain APG6_N PF17675.1 GAP91884.1 - 0.0043 17.6 19.0 81 3.7 19.0 2.8 1 1 0 1 1 1 0 Apg6 coiled-coil region RasGAP_C PF03836.15 GAP91884.1 - 0.0044 17.2 21.0 0.21 11.7 1.3 3.6 1 1 1 2 2 2 1 RasGAP C-terminus DUF4618 PF15397.6 GAP91884.1 - 0.0045 16.4 27.1 0.79 9.1 4.5 4.1 1 1 3 4 4 4 1 Domain of unknown function (DUF4618) DUF1043 PF06295.12 GAP91884.1 - 0.0049 16.9 14.1 1.1 9.2 1.1 4.3 1 1 3 4 4 3 0 Protein of unknown function (DUF1043) TTKRSYEDQ PF10212.9 GAP91884.1 - 0.0049 15.9 8.8 0.12 11.4 1.3 2.5 1 1 0 2 2 2 2 Predicted coiled-coil domain-containing protein DASH_Duo1 PF08651.10 GAP91884.1 - 0.005 16.6 16.4 0.94 9.3 0.1 5.9 1 1 6 7 7 7 0 DASH complex subunit Duo1 CENP-F_leu_zip PF10473.9 GAP91884.1 - 0.0052 16.8 27.2 0.86 9.6 8.3 3.5 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 THOC7 PF05615.13 GAP91884.1 - 0.0054 17.0 18.9 0.13 12.5 5.0 2.8 1 1 1 2 2 2 1 Tho complex subunit 7 DUF2408 PF10303.9 GAP91884.1 - 0.0056 17.2 9.5 0.0056 17.2 9.5 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF2408) RmuC PF02646.16 GAP91884.1 - 0.0068 15.6 21.4 0.24 10.5 2.4 3.9 1 1 4 5 5 5 2 RmuC family PI3K_P85_iSH2 PF16454.5 GAP91884.1 - 0.0068 16.0 16.3 0.39 10.3 3.3 3.7 1 1 2 3 3 3 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Baculo_p24 PF05073.12 GAP91884.1 - 0.0072 16.1 23.7 0.21 11.3 4.2 3.2 1 1 2 3 3 3 2 Baculovirus P24 capsid protein KfrA_N PF11740.8 GAP91884.1 - 0.008 16.8 5.5 3.4 8.4 0.2 3.6 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term YtxH PF12732.7 GAP91884.1 - 0.0092 16.5 32.8 2.9 8.5 0.4 4.9 1 1 2 3 3 3 0 YtxH-like protein DNA_repr_REX1B PF14966.6 GAP91884.1 - 0.0092 16.6 17.6 3.1 8.5 0.8 5.1 1 1 6 7 7 7 0 DNA repair REX1-B Sec8_exocyst PF04048.14 GAP91884.1 - 0.0097 15.8 20.9 0.73 9.7 2.3 4.5 1 1 3 4 4 4 1 Sec8 exocyst complex component specific domain DUF1515 PF07439.11 GAP91884.1 - 0.0099 15.9 23.7 0.16 12.0 1.1 4.0 1 1 2 3 3 3 2 Protein of unknown function (DUF1515) Gp58 PF07902.11 GAP91884.1 - 0.01 14.2 21.2 0.015 13.6 21.2 1.2 1 0 0 1 1 1 0 gp58-like protein DUF5082 PF16888.5 GAP91884.1 - 0.01 16.1 24.6 0.035 14.4 10.8 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) DUF3450 PF11932.8 GAP91884.1 - 0.012 14.9 20.6 0.031 13.6 5.6 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 GAP91884.1 - 0.012 15.2 19.6 0.068 12.7 7.8 2.6 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Bacillus_HBL PF05791.11 GAP91884.1 - 0.013 15.4 6.8 0.013 15.4 6.8 3.5 1 1 3 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Sec34 PF04136.15 GAP91884.1 - 0.014 15.3 18.6 0.71 9.7 1.3 4.3 1 1 3 4 4 4 0 Sec34-like family Lectin_N PF03954.14 GAP91884.1 - 0.014 15.2 3.1 0.014 15.2 3.1 3.5 1 1 4 5 5 5 0 Hepatic lectin, N-terminal domain ISG65-75 PF11727.8 GAP91884.1 - 0.016 14.4 22.4 0.072 12.3 5.0 2.7 1 1 2 3 3 3 0 Invariant surface glycoprotein Rx_N PF18052.1 GAP91884.1 - 0.018 15.3 18.5 0.84 10.0 1.4 4.7 1 1 3 4 4 4 0 Rx N-terminal domain Seryl_tRNA_N PF02403.22 GAP91884.1 - 0.018 15.3 31.0 0.4 10.9 9.2 4.1 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 GAP91884.1 - 0.018 15.2 32.0 0.084 13.0 6.9 3.6 1 1 2 3 3 3 0 Tropomyosin like FmiP_Thoc5 PF09766.9 GAP91884.1 - 0.019 14.3 23.4 0.049 12.9 2.7 3.9 1 1 3 4 4 4 0 Fms-interacting protein/Thoc5 DUF4795 PF16043.5 GAP91884.1 - 0.02 14.5 29.7 0.74 9.4 29.5 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Muted PF14942.6 GAP91884.1 - 0.02 15.2 23.8 0.29 11.5 8.9 3.2 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein Spectrin PF00435.21 GAP91884.1 - 0.02 15.4 18.2 1.6 9.2 3.9 3.7 1 1 2 3 3 3 0 Spectrin repeat Lipoprotein_2 PF00921.17 GAP91884.1 - 0.021 14.4 31.6 0.047 13.2 19.6 2.5 1 1 1 2 2 2 0 Borrelia lipoprotein Fzo_mitofusin PF04799.13 GAP91884.1 - 0.022 14.3 21.7 0.99 8.9 6.7 4.1 1 1 3 4 4 4 0 fzo-like conserved region EspB PF05802.11 GAP91884.1 - 0.023 14.7 24.7 0.11 12.4 6.4 3.8 1 1 2 3 3 3 0 Enterobacterial EspB protein Snapin_Pallidin PF14712.6 GAP91884.1 - 0.027 14.9 24.1 2.6 8.5 3.1 4.8 1 1 5 6 6 6 0 Snapin/Pallidin DUF883 PF05957.13 GAP91884.1 - 0.027 15.1 16.5 7.5 7.2 2.8 4.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF2390 PF09523.10 GAP91884.1 - 0.03 14.7 4.4 1.2 9.4 0.4 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2390) FliD_C PF07195.12 GAP91884.1 - 0.032 13.7 23.6 0.26 10.7 5.4 3.7 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF1845 PF08900.11 GAP91884.1 - 0.034 13.9 13.2 1.8 8.2 0.1 4.7 2 1 4 6 6 6 0 Domain of unknown function (DUF1845) Fmp27_WPPW PF10359.9 GAP91884.1 - 0.034 13.0 21.1 1.6 7.4 9.8 2.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FUSC PF04632.12 GAP91884.1 - 0.038 12.5 0.1 1.5 7.3 0.0 2.1 1 1 0 2 2 2 0 Fusaric acid resistance protein family Fez1 PF06818.15 GAP91884.1 - 0.041 14.3 24.1 0.3 11.5 9.3 2.6 1 1 1 2 2 2 0 Fez1 TelA PF05816.11 GAP91884.1 - 0.042 12.9 21.6 0.21 10.6 5.9 2.6 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) DUF713 PF05218.14 GAP91884.1 - 0.044 13.5 11.4 0.66 9.7 1.9 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF713) DUF1319 PF07028.11 GAP91884.1 - 0.045 14.0 18.8 2 8.7 1.8 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) zf-C4H2 PF10146.9 GAP91884.1 - 0.046 14.0 21.0 0.012 16.0 11.9 2.9 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4088 PF13317.6 GAP91884.1 - 0.051 13.1 4.4 2.7 7.5 0.3 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4088) Talin_middle PF09141.10 GAP91884.1 - 0.054 13.5 14.4 0.02 14.9 7.0 2.6 1 1 1 2 2 2 0 Talin, middle domain Tweety PF04906.13 GAP91884.1 - 0.056 12.1 16.1 0.72 8.4 0.2 3.2 1 1 2 3 3 3 0 Tweety Plasmid_RAQPRD PF09686.10 GAP91884.1 - 0.058 13.6 8.5 3.1 8.1 0.7 5.0 1 1 5 6 6 5 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TACC_C PF05010.14 GAP91884.1 - 0.06 13.1 23.3 0.71 9.6 9.0 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Med30 PF11315.8 GAP91884.1 - 0.061 13.5 19.6 0.69 10.1 4.9 4.0 1 1 3 4 4 4 0 Mediator complex subunit 30 Rootletin PF15035.6 GAP91884.1 - 0.064 13.3 14.2 0.3 11.1 2.1 2.9 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion WXG100 PF06013.12 GAP91884.1 - 0.073 13.3 10.9 16 5.8 0.2 5.7 2 1 3 6 6 4 0 Proteins of 100 residues with WXG Nup88 PF10168.9 GAP91884.1 - 0.074 10.9 21.2 0.09 10.6 20.5 1.4 1 1 0 1 1 1 0 Nuclear pore component GrpE PF01025.19 GAP91884.1 - 0.075 12.7 23.4 0.063 12.9 7.7 3.0 1 1 2 3 3 3 0 GrpE CorA PF01544.18 GAP91884.1 - 0.078 12.3 15.5 0.84 8.9 1.1 3.1 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein Tropomyosin PF00261.20 GAP91884.1 - 0.08 12.3 25.8 0.24 10.8 8.1 3.3 1 1 2 3 3 3 0 Tropomyosin DUF16 PF01519.16 GAP91884.1 - 0.084 13.4 32.3 0.43 11.1 7.3 4.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 Dynamitin PF04912.14 GAP91884.1 - 0.084 12.2 26.0 0.51 9.6 2.0 3.8 1 1 3 4 4 4 0 Dynamitin CCD PF07860.11 GAP91884.1 - 0.084 12.9 14.4 13 5.9 0.2 5.2 1 1 3 5 5 5 0 WisP family C-Terminal Region Med9 PF07544.13 GAP91884.1 - 0.087 12.9 25.9 0.25 11.4 3.9 4.5 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 YabA PF06156.13 GAP91884.1 - 0.093 13.4 16.8 1.8 9.3 0.9 4.0 1 1 2 3 3 2 0 Initiation control protein YabA FAP206 PF12018.8 GAP91884.1 - 0.099 12.1 11.0 0.14 11.7 1.5 3.2 1 1 2 3 3 3 0 Domain of unknown function ASL_C PF08328.11 GAP91884.1 - 0.11 12.6 12.5 0.31 11.2 0.3 3.7 1 1 2 3 3 3 0 Adenylosuccinate lyase C-terminal Rho_Binding PF08912.11 GAP91884.1 - 0.11 13.3 25.5 20 6.1 2.9 6.1 2 1 4 6 6 6 0 Rho Binding Mod_r PF07200.13 GAP91884.1 - 0.12 12.5 19.4 4.4 7.4 8.3 3.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein OEP PF02321.18 GAP91884.1 - 0.12 12.2 7.0 4 7.2 0.8 2.9 1 1 1 2 2 2 0 Outer membrane efflux protein YkyA PF10368.9 GAP91884.1 - 0.12 12.0 28.7 0.17 11.6 10.1 2.7 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Peptidase_M61 PF05299.12 GAP91884.1 - 0.12 12.8 2.6 1.9 8.9 0.1 3.3 1 1 3 4 4 3 0 M61 glycyl aminopeptidase DUF5320 PF17253.2 GAP91884.1 - 0.13 13.3 14.3 44 5.2 0.7 5.6 1 1 2 5 5 4 0 Family of unknown function (DUF5320) XhlA PF10779.9 GAP91884.1 - 0.14 12.4 32.0 0.49 10.6 2.8 5.2 2 1 3 5 5 5 0 Haemolysin XhlA MitMem_reg PF13012.6 GAP91884.1 - 0.14 12.6 13.7 22 5.5 6.5 3.9 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function PLA2G12 PF06951.11 GAP91884.1 - 0.15 11.9 8.3 13 5.7 0.3 4.0 1 1 3 4 4 4 0 Group XII secretory phospholipase A2 precursor (PLA2G12) ZapB PF06005.12 GAP91884.1 - 0.15 12.5 14.6 2.9 8.4 1.2 4.5 1 1 3 4 4 3 0 Cell division protein ZapB YojJ PF10372.9 GAP91884.1 - 0.16 12.1 17.9 3.5 7.8 0.3 5.3 1 1 4 6 6 6 0 Bacterial membrane-spanning protein N-terminus DUF1451 PF07295.11 GAP91884.1 - 0.16 12.0 19.4 2.8 8.0 2.9 4.0 1 1 3 4 4 3 0 Zinc-ribbon containing domain DUF2203 PF09969.9 GAP91884.1 - 0.2 12.4 18.5 16 6.2 0.9 3.9 1 1 1 2 2 1 0 Uncharacterized conserved protein (DUF2203) DUF4208 PF13907.6 GAP91884.1 - 0.21 12.0 19.0 0.063 13.7 2.8 3.9 2 1 2 4 4 3 0 Domain of unknown function (DUF4208) DUF1351 PF07083.11 GAP91884.1 - 0.23 11.2 25.3 1.7 8.3 11.1 3.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1351) DUF4140 PF13600.6 GAP91884.1 - 0.24 11.8 20.4 7e+03 -2.5 0.0 5.1 1 1 1 2 2 0 0 N-terminal domain of unknown function (DUF4140) Vps53_N PF04100.12 GAP91884.1 - 0.24 10.3 27.4 0.93 8.4 9.9 3.1 1 1 2 3 3 3 0 Vps53-like, N-terminal PRD PF00874.20 GAP91884.1 - 0.27 11.5 3.6 7.4 7.0 0.2 3.3 3 1 0 3 3 2 0 PRD domain BicD PF09730.9 GAP91884.1 - 0.28 9.6 25.1 1.3 7.4 15.9 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D DegS PF05384.11 GAP91884.1 - 0.3 10.6 20.1 2 7.9 12.0 3.3 1 1 1 2 2 2 0 Sensor protein DegS CENP-Q PF13094.6 GAP91884.1 - 0.33 11.1 18.1 0.098 12.9 10.9 2.8 1 1 2 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3037 PF11236.8 GAP91884.1 - 0.34 11.3 5.1 17 5.9 0.2 3.8 1 1 3 4 4 3 0 Protein of unknown function (DUF3037) DUF724 PF05266.14 GAP91884.1 - 0.41 10.5 22.7 1.5 8.6 6.8 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF724) EMP24_GP25L PF01105.24 GAP91884.1 - 0.45 10.4 23.0 5.2 7.0 3.1 4.6 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD MCPsignal PF00015.21 GAP91884.1 - 0.48 10.2 19.8 0.83 9.5 1.4 3.3 1 1 3 4 4 4 0 Methyl-accepting chemotaxis protein (MCP) signalling domain YscO PF07321.12 GAP91884.1 - 0.49 10.3 15.4 0.81 9.6 0.7 3.3 1 1 1 3 3 3 0 Type III secretion protein YscO RPW8 PF05659.11 GAP91884.1 - 0.52 10.0 18.2 0.68 9.6 1.0 4.2 1 1 3 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Sulfatase_C PF14707.6 GAP91884.1 - 0.52 11.0 5.6 67 4.2 2.1 3.8 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase BLOC1_2 PF10046.9 GAP91884.1 - 0.54 10.6 21.3 4.2 7.7 2.5 4.5 1 1 4 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LMP PF04778.12 GAP91884.1 - 0.6 10.0 34.9 0.65 9.9 7.1 3.8 1 1 1 3 3 3 0 LMP repeated region DUF4200 PF13863.6 GAP91884.1 - 0.62 10.5 17.3 5.4 7.4 7.4 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Flagellar_rod PF05149.12 GAP91884.1 - 0.66 9.4 19.9 0.86 9.0 2.6 3.7 1 1 0 2 2 2 0 Paraflagellar rod protein DUF4407 PF14362.6 GAP91884.1 - 0.79 9.0 18.4 1.4e+02 1.7 18.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PEP-utilisers_N PF05524.13 GAP91884.1 - 0.82 9.9 11.0 2.8e+03 -1.5 10.9 4.3 1 1 0 1 1 0 0 PEP-utilising enzyme, N-terminal NEMO PF11577.8 GAP91884.1 - 0.83 9.7 4.5 3.4 7.8 0.2 3.1 2 1 1 3 3 2 0 NF-kappa-B essential modulator NEMO DUF3552 PF12072.8 GAP91884.1 - 0.87 9.0 24.5 0.52 9.7 8.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF4047 PF13256.6 GAP91884.1 - 0.92 9.7 17.6 6.3 7.0 0.6 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4047) Allexi_40kDa PF05549.11 GAP91884.1 - 0.94 8.9 21.8 1.7 8.1 1.8 3.1 1 1 2 3 3 3 0 Allexivirus 40kDa protein Nre_C PF04895.12 GAP91884.1 - 1 9.3 7.2 12 5.9 0.2 3.9 1 1 2 4 4 3 0 Archaeal Nre, C-terminal DUF4164 PF13747.6 GAP91884.1 - 1.1 9.6 20.0 3.4 8.0 5.1 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4164) DUF5089 PF17002.5 GAP91884.1 - 1.1 9.1 28.2 8.8 6.2 11.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) Cytochrom_B562 PF07361.11 GAP91884.1 - 1.1 10.0 18.3 1.7 9.4 4.2 3.8 1 1 3 4 4 3 0 Cytochrome b562 Mitofilin PF09731.9 GAP91884.1 - 1.1 8.0 25.9 2.3 7.0 25.8 1.4 1 1 0 1 1 1 0 Mitochondrial inner membrane protein DUF4446 PF14584.6 GAP91884.1 - 1.5 8.8 19.4 8.1 6.4 2.4 4.1 1 1 4 5 5 5 0 Protein of unknown function (DUF4446) DUF2935 PF11155.8 GAP91884.1 - 1.5 9.1 7.0 1.7 9.0 0.5 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) Cluap1 PF10234.9 GAP91884.1 - 1.6 8.1 28.5 4.3 6.6 9.7 3.3 1 1 2 3 3 3 0 Clusterin-associated protein-1 SOGA PF11365.8 GAP91884.1 - 1.8 9.8 13.8 6.3 8.0 0.5 3.3 1 1 2 3 3 2 0 Protein SOGA Tho2 PF11262.8 GAP91884.1 - 1.9 7.6 18.1 18 4.4 5.5 3.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF2312 PF10073.9 GAP91884.1 - 2 8.1 18.8 15 5.3 1.1 5.4 1 1 4 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2312) Cauli_AT PF03233.13 GAP91884.1 - 2.1 8.3 33.3 5.1 7.0 3.0 4.5 1 1 4 5 5 5 0 Aphid transmission protein BST2 PF16716.5 GAP91884.1 - 2.1 9.0 21.6 1.8 9.2 3.4 3.5 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF2968 PF11180.8 GAP91884.1 - 2.3 7.8 13.9 1 9.0 2.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) Bac_GDH PF05088.12 GAP91884.1 - 2.3 5.6 17.6 1.2 6.5 3.5 2.3 1 1 1 2 2 2 0 Bacterial NAD-glutamate dehydrogenase UPF0449 PF15136.6 GAP91884.1 - 2.4 8.7 20.9 3.1 8.3 5.7 4.4 2 2 1 3 3 3 0 Uncharacterised protein family UPF0449 V_ATPase_I PF01496.19 GAP91884.1 - 2.4 6.0 19.4 4.8 5.0 6.5 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Dynamin_M PF01031.20 GAP91884.1 - 2.5 7.3 14.1 1.6 7.9 5.3 2.8 1 1 1 2 2 2 0 Dynamin central region ANAPC4 PF12896.7 GAP91884.1 - 2.6 7.5 7.7 1.5e+02 1.7 0.1 3.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Phasin PF05597.11 GAP91884.1 - 2.8 8.0 26.3 2.2 8.3 1.7 4.4 1 1 3 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CLZ PF16526.5 GAP91884.1 - 3.1 8.2 20.2 0.61 10.5 0.6 4.3 1 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaC_arch PF05377.11 GAP91884.1 - 3.3 8.2 30.7 0.61 10.5 1.0 6.6 1 1 2 4 4 2 0 Flagella accessory protein C (FlaC) DUF489 PF04356.12 GAP91884.1 - 3.8 7.5 8.8 8.6 6.3 1.3 2.9 1 1 2 3 3 2 0 Protein of unknown function (DUF489) CC2-LZ PF16516.5 GAP91884.1 - 3.8 7.9 23.3 12 6.4 4.2 4.3 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Lysozyme_like PF13702.6 GAP91884.1 - 4.1 7.1 11.1 18 5.0 0.2 3.7 1 1 3 4 4 4 0 Lysozyme-like CREPT PF16566.5 GAP91884.1 - 4.2 7.5 18.9 18 5.4 8.1 3.3 1 1 2 3 3 2 0 Cell-cycle alteration and expression-elevated protein in tumour PRKG1_interact PF15898.5 GAP91884.1 - 4.2 8.3 22.5 7.4 7.5 6.0 4.0 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain End3 PF12761.7 GAP91884.1 - 4.4 7.4 29.0 8.5 6.5 13.0 3.8 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 PMEI PF04043.15 GAP91884.1 - 5.3 7.4 9.9 3.7e+02 1.4 9.9 2.9 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor YscO-like PF16789.5 GAP91884.1 - 5.3 7.1 25.4 12 5.9 12.8 3.1 1 1 2 3 3 3 0 YscO-like protein Mei5 PF10376.9 GAP91884.1 - 5.4 6.8 27.0 5.8 6.7 11.7 3.4 1 1 2 3 3 3 0 Double-strand recombination repair protein ATG16 PF08614.11 GAP91884.1 - 5.9 7.1 25.2 19 5.4 9.1 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 GAP91884.1 - 6.3 6.9 22.0 20 5.2 5.8 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TFA2_Winged_2 PF18121.1 GAP91884.1 - 7.2 6.4 13.5 40 4.0 0.6 4.4 1 1 1 2 2 2 0 TFA2 Winged helix domain 2 Nup54 PF13874.6 GAP91884.1 - 8 6.6 14.3 1.7e+02 2.3 4.1 3.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 COG5 PF10392.9 GAP91884.1 - 8.1 6.6 22.5 9.2 6.4 6.1 3.3 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Nsp1_C PF05064.13 GAP91884.1 - 8.6 6.2 16.5 4.6 7.1 4.4 3.2 1 1 2 3 3 2 0 Nsp1-like C-terminal region Corona_S2 PF01601.16 GAP91884.1 - 9.1 4.6 10.8 2.4 6.5 2.3 2.5 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein DUF3810 PF12725.7 GAP91884.1 - 9.5 5.5 12.8 5.4 6.3 3.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3810) Mer2 PF09074.10 GAP91884.1 - 9.6 6.0 31.9 1.5 8.6 10.8 2.6 1 1 1 2 2 2 0 Mer2 TPR_2 PF07719.17 GAP91885.1 - 0.00044 20.1 6.4 0.29 11.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 GAP91885.1 - 0.00094 18.9 7.2 0.019 14.8 0.2 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAP91885.1 - 0.001 19.3 2.2 0.001 19.3 2.2 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAP91885.1 - 0.0039 17.1 2.9 1.3 9.2 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAP91885.1 - 0.023 15.2 1.6 0.023 15.2 1.6 2.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 GAP91885.1 - 0.069 12.9 3.6 0.12 12.1 0.6 2.3 2 0 0 2 2 2 0 TPR repeat ANAPC3 PF12895.7 GAP91885.1 - 0.35 11.1 5.4 1.8 8.9 5.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Amidase PF01425.21 GAP91886.1 - 2.4e-85 287.2 0.0 8.7e-83 278.8 0.0 3.3 1 1 0 1 1 1 1 Amidase CDC27 PF09507.10 GAP91887.1 - 1.5e-80 271.7 28.4 2.7e-80 270.9 28.4 1.4 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 CDC45 PF02724.14 GAP91887.1 - 6.1 5.0 12.0 8.7 4.5 12.0 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-C3HC4_2 PF13923.6 GAP91888.1 - 9e-13 47.8 14.5 1.2e-12 47.4 9.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP91888.1 - 2.3e-09 37.1 9.5 1.6e-08 34.4 6.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 GAP91888.1 - 2.4e-09 36.9 14.7 3.3e-09 36.4 9.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP91888.1 - 2.5e-07 30.4 7.0 2.5e-07 30.4 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP91888.1 - 3e-07 30.7 12.3 1.3e-06 28.7 8.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 GAP91888.1 - 4.6e-07 29.7 13.0 5.5e-07 29.4 8.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 GAP91888.1 - 6.3e-07 29.2 11.5 7.3e-05 22.6 6.9 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 GAP91888.1 - 1.3e-06 28.6 6.4 1.9e-06 28.0 2.9 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain SAP PF02037.27 GAP91888.1 - 4.4e-06 26.3 0.0 8.9e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.6 GAP91888.1 - 2.8e-05 24.2 9.3 2.8e-05 24.2 9.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 GAP91888.1 - 5.7e-05 22.9 2.7 5.7e-05 22.9 2.7 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 GAP91888.1 - 0.0035 17.4 4.2 0.0035 17.4 4.2 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 GAP91888.1 - 0.0036 17.0 2.9 0.0036 17.0 2.9 2.8 2 1 0 3 3 3 1 RING/Ubox like zinc-binding domain Mob_synth_C PF06463.13 GAP91888.1 - 0.0083 16.1 3.2 0.02 14.8 3.2 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C EBV-NA3 PF05009.12 GAP91888.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Rad50_zn_hook PF04423.14 GAP91888.1 - 0.035 14.0 1.2 5.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 GAP91888.1 - 0.043 13.9 0.9 0.043 13.9 0.9 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_recom PF13408.6 GAP91888.1 - 0.71 10.4 3.4 1.4 9.5 0.0 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc-ribbons_6 PF07191.12 GAP91888.1 - 3.2 7.8 8.7 17 5.5 5.4 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-Di19 PF05605.12 GAP91888.1 - 9 6.7 9.2 2.4 8.5 0.3 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Snf7 PF03357.21 GAP91889.1 - 6.6e-16 58.4 7.3 9.5e-16 57.9 7.3 1.2 1 0 0 1 1 1 1 Snf7 Metalloenzyme PF01676.18 GAP91889.1 - 0.2 11.0 0.4 0.34 10.2 0.4 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily IPPT PF01715.17 GAP91889.1 - 0.36 10.6 4.8 2.1 8.1 1.9 2.9 2 1 1 3 3 3 0 IPP transferase HAUS-augmin3 PF14932.6 GAP91889.1 - 1.1 8.7 8.1 0.041 13.5 2.2 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF932 PF06067.11 GAP91889.1 - 6.6 6.4 9.0 2.2 8.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF932) PPR_2 PF13041.6 GAP91892.1 - 6.2e-45 151.2 6.6 1.6e-08 34.6 0.0 13.3 11 4 5 16 16 16 9 PPR repeat family PPR_3 PF13812.6 GAP91892.1 - 1e-31 108.8 2.6 0.00037 20.5 0.1 11.6 7 3 7 14 14 14 7 Pentatricopeptide repeat domain PPR PF01535.20 GAP91892.1 - 2.8e-23 80.5 30.1 0.0003 20.8 0.0 13.5 18 0 0 18 18 18 5 PPR repeat PPR_1 PF12854.7 GAP91892.1 - 8.9e-23 79.7 1.2 1.4e-07 31.1 0.0 9.2 10 0 0 10 10 10 5 PPR repeat PPR_long PF17177.4 GAP91892.1 - 3.2e-19 69.1 9.8 1.6e-06 27.7 0.2 5.9 4 1 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 GAP91892.1 - 0.0026 18.1 0.0 0.061 13.7 0.0 3.2 3 1 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 GAP91892.1 - 0.053 13.4 0.1 0.3 10.9 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATPase expression TPR_14 PF13428.6 GAP91892.1 - 0.59 11.1 5.0 80 4.5 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 GAP91893.1 - 4.1e-45 153.7 0.1 6.2e-45 153.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP91893.1 - 1.2e-20 73.9 0.0 5.6e-20 71.7 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 GAP91893.1 - 8.2e-14 51.6 0.1 1.7e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 GAP91893.1 - 2e-05 24.7 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 GAP91893.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase TRAPPC-Trs85 PF12739.7 GAP91894.1 - 5.8e-114 381.2 3.5 5.9e-114 381.2 0.0 2.0 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Acetyltransf_7 PF13508.7 GAP91895.1 - 3.7e-06 27.3 0.0 6.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP91895.1 - 4.8e-06 26.8 0.0 7.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP91895.1 - 0.00018 21.5 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP91895.1 - 0.0071 16.4 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mpp10 PF04006.12 GAP91896.1 - 8.2e-05 21.3 25.4 0.00011 20.8 25.4 1.1 1 0 0 1 1 1 1 Mpp10 protein RNA_pol_Rpc4 PF05132.14 GAP91896.1 - 0.014 15.8 16.1 0.016 15.7 14.2 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Merozoite_SPAM PF07133.11 GAP91896.1 - 0.024 14.7 41.8 0.04 13.9 41.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) zf-C2H2 PF00096.26 GAP91896.1 - 0.078 13.5 3.9 1.7 9.2 0.2 3.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Rrn6 PF10214.9 GAP91896.1 - 0.13 10.7 3.3 0.18 10.3 3.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Sec62 PF03839.16 GAP91896.1 - 0.16 11.5 16.5 0.24 10.9 16.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 VIR_N PF15912.5 GAP91896.1 - 0.33 10.5 15.2 0.52 9.9 15.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal CDC45 PF02724.14 GAP91896.1 - 0.33 9.2 29.6 0.49 8.6 29.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 GAP91896.1 - 0.36 10.9 5.3 0.61 10.1 5.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDM1 PF15501.6 GAP91896.1 - 0.92 8.6 24.2 1.4 7.9 24.2 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 DUF2052 PF09747.9 GAP91896.1 - 1.1 9.3 29.2 2.1 8.5 29.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF5427 PF10310.9 GAP91896.1 - 1.2 8.1 20.1 1.9 7.4 20.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SAPS PF04499.15 GAP91896.1 - 1.4 7.6 12.4 2.2 7.0 12.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 GAP91896.1 - 1.7 8.4 30.4 2.8 7.7 30.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 GAP91896.1 - 1.9 6.6 37.0 3.4 5.8 37.0 1.3 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 GAP91896.1 - 2 7.3 10.5 4.7 6.1 10.5 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIP PF07454.11 GAP91896.1 - 2.4 7.5 19.4 4.8 6.6 19.4 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.10 GAP91896.1 - 2.7 8.3 32.7 5.1 7.4 32.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 GAP91896.1 - 3.7 6.7 12.7 5.4 6.1 12.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.6 GAP91896.1 - 5.2 5.7 13.6 7.9 5.1 13.6 1.2 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 GAP91896.1 - 6.3 5.7 16.4 10 5.0 16.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 AAA_11 PF13086.6 GAP91896.1 - 7.6 6.2 16.7 14 5.4 16.7 1.3 1 0 0 1 1 1 0 AAA domain Paf1 PF03985.13 GAP91896.1 - 8.7 5.2 37.2 13 4.7 37.2 1.2 1 0 0 1 1 1 0 Paf1 Corazonin PF17308.2 GAP91898.1 - 0.015 15.7 4.0 0.027 14.8 4.0 1.3 1 0 0 1 1 1 0 Pro-corazonin Menin PF05053.13 GAP91898.1 - 0.18 10.1 1.2 0.25 9.7 1.2 1.1 1 0 0 1 1 1 0 Menin GCD14 PF08704.10 GAP91898.1 - 0.19 11.4 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Secretin_N_2 PF07655.13 GAP91898.1 - 0.41 11.2 11.5 0.69 10.5 11.5 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Transferase PF02458.15 GAP91899.1 - 3.2e-37 128.2 0.0 9.1e-16 57.5 0.0 3.0 3 0 0 3 3 3 3 Transferase family FAD_binding_4 PF01565.23 GAP91900.1 - 1.3e-17 63.8 0.0 2.1e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP91900.1 - 0.32 11.1 0.1 0.32 11.1 0.1 2.4 3 0 0 3 3 3 0 Berberine and berberine like Esterase PF00756.20 GAP91902.1 - 1.7e-05 24.6 0.0 0.00011 21.9 0.0 2.2 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 GAP91902.1 - 4.1e-05 23.2 0.2 0.052 13.0 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family FAD_binding_2 PF00890.24 GAP91903.1 - 1.3e-55 189.2 11.2 1.6e-55 188.9 11.2 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAP91903.1 - 1.7e-06 28.2 1.0 6.5e-06 26.3 1.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP91903.1 - 6e-06 26.1 7.1 3.5e-05 23.5 5.7 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAP91903.1 - 0.00093 18.7 2.3 0.0028 17.1 2.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP91903.1 - 0.032 13.4 0.1 0.077 12.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP91903.1 - 0.09 12.0 1.0 0.25 10.5 0.1 2.1 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.22 GAP91903.1 - 0.86 8.6 8.4 0.22 10.6 2.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A PGM_PMM_I PF02878.16 GAP91904.1 - 6.6e-34 116.6 0.0 9.7e-34 116.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 GAP91904.1 - 8.1e-26 90.5 0.0 1.4e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 GAP91904.1 - 6e-15 55.7 0.0 1.2e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 GAP91904.1 - 2e-05 24.7 0.0 4.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.24 GAP91905.1 - 3.3e-27 96.0 0.0 3.8e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Exonuclease APH PF01636.23 GAP91906.1 - 2e-17 63.9 2.3 2e-17 63.9 2.3 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP91906.1 - 0.00027 20.6 0.0 0.00052 19.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 GAP91906.1 - 0.0097 15.5 0.0 3.8 7.1 0.0 2.6 1 1 1 2 2 2 2 RIO1 family Pkinase_Tyr PF07714.17 GAP91906.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase AA_permease_2 PF13520.6 GAP91907.1 - 2.8e-58 197.8 16.6 3.7e-58 197.4 16.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP91907.1 - 1.7e-18 66.5 24.0 1.7e-18 66.5 24.0 2.3 2 1 0 2 2 2 1 Amino acid permease Cation_ATPase_C PF00689.21 GAP91907.1 - 0.063 13.0 2.5 0.19 11.5 1.1 2.4 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Spore_permease PF03845.13 GAP91907.1 - 0.67 8.7 10.1 0.066 12.0 0.7 3.4 3 1 0 4 4 4 0 Spore germination protein TALPID3 PF15324.6 GAP91908.1 - 2.2 5.8 7.2 3 5.4 7.2 1.1 1 0 0 1 1 1 0 Hedgehog signalling target VSP PF03302.13 GAP91909.1 - 0.0028 16.6 2.2 0.0056 15.6 2.2 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.10 GAP91909.1 - 1.2 8.6 6.4 0.42 10.1 0.3 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Xpo1 PF08389.12 GAP91910.1 - 6.6e-28 97.6 3.6 7.9e-28 97.4 0.9 2.7 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 GAP91910.1 - 7e-05 22.7 0.1 0.00063 19.6 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain UME PF08064.13 GAP91910.1 - 0.00074 19.4 0.9 0.94 9.4 0.0 4.6 4 1 1 5 5 5 1 UME (NUC010) domain Adaptin_N PF01602.20 GAP91910.1 - 0.011 14.4 1.7 0.21 10.1 0.3 2.5 2 0 0 2 2 2 0 Adaptin N terminal region Importin_rep_3 PF18806.1 GAP91910.1 - 0.021 14.8 0.0 1.9 8.6 0.0 3.1 2 0 0 2 2 2 0 Importin 13 repeat Tab2_like PF06485.11 GAP91910.1 - 0.061 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 GAT PF03127.14 GAP91910.1 - 0.094 13.0 0.2 0.99 9.8 0.0 2.9 3 0 0 3 3 3 0 GAT domain 5-FTHF_cyc-lig PF01812.20 GAP91911.1 - 6e-29 101.2 0.0 1e-28 100.5 0.0 1.4 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family OPT PF03169.15 GAP91913.1 - 7.9e-205 682.1 34.6 9.2e-205 681.9 34.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.16 GAP91914.1 - 0.027 13.4 0.3 0.041 12.8 0.3 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily SLATT_fungal PF18142.1 GAP91915.1 - 1.8e-29 102.1 0.1 2.5e-29 101.7 0.1 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain SLATT_1 PF18181.1 GAP91915.1 - 0.2 11.6 0.3 0.3 11.0 0.3 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 GTP_EFTU PF00009.27 GAP91916.1 - 4.2e-67 225.5 0.3 6.1e-67 224.9 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAP91916.1 - 4.5e-33 113.6 0.0 1.4e-32 112.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 GAP91916.1 - 2.1e-21 75.8 0.0 7.6e-21 74.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAP91916.1 - 1.1e-13 51.3 1.9 1.7e-13 50.8 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 GAP91916.1 - 4.6e-12 45.8 0.0 1.4e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 GAP91916.1 - 0.00039 20.5 0.3 0.00094 19.2 0.3 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.16 GAP91918.1 - 1.3e-99 333.0 11.6 1.5e-99 332.8 11.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4293 PF14126.6 GAP91918.1 - 0.064 13.5 1.2 0.15 12.3 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Glyco_hydro_92 PF07971.12 GAP91919.1 - 1.5e-137 459.3 0.0 1.9e-137 459.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAP91919.1 - 2.5e-50 171.6 4.1 3.5e-50 171.1 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Isochorismatase PF00857.20 GAP91920.1 - 2.9e-18 66.6 0.1 4.4e-18 66.1 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family Zn_clus PF00172.18 GAP91921.1 - 0.027 14.6 6.5 0.069 13.3 6.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.6 GAP91921.1 - 0.2 11.7 3.3 3.5 7.7 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Iso_dh PF00180.20 GAP91922.1 - 1.8e-100 336.5 0.0 2.2e-100 336.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 GAP91922.1 - 0.0081 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage protein GP30.3 HHH_2 PF12826.7 GAP91922.1 - 0.11 12.6 0.0 0.68 10.1 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sec5 PF15469.6 GAP91923.1 - 2.2e-38 132.0 0.0 1.4e-37 129.3 0.0 2.4 3 0 0 3 3 3 1 Exocyst complex component Sec5 Sec15 PF04091.12 GAP91923.1 - 4e-05 23.2 0.3 7.3e-05 22.3 0.3 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 GAP91923.1 - 0.00033 20.7 0.7 0.0014 18.6 0.1 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Oxysterol_BP PF01237.18 GAP91925.1 - 6.4e-61 206.2 4.2 1.8e-53 181.7 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein YfdX PF10938.8 GAP91925.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 YfdX protein DUF2956 PF11169.8 GAP91925.1 - 1.8 8.8 5.4 0.25 11.6 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Fringe PF02434.16 GAP91926.1 - 1.7e-05 24.4 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 GAP91926.1 - 0.001 19.0 0.1 0.0018 18.2 0.1 1.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 GAP91926.1 - 0.025 14.5 1.2 0.051 13.5 1.2 1.5 1 0 0 1 1 1 0 PAN domain CFEM PF05730.11 GAP91927.1 - 6e-15 55.1 10.1 1e-14 54.4 10.1 1.4 1 0 0 1 1 1 1 CFEM domain Asn_synthase PF00733.21 GAP91928.1 - 1.1e-19 71.4 1.1 9e-09 35.4 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 GAP91928.1 - 1.1e-08 35.0 0.0 1.7e-07 31.2 0.0 2.9 3 1 0 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.6 GAP91928.1 - 0.0015 18.7 0.0 0.12 12.6 0.0 2.8 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 GAP91928.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Aluminium induced protein AMP-binding PF00501.28 GAP91929.1 - 1.1e-63 215.3 0.0 2e-63 214.5 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 GAP91929.1 - 7.2e-12 46.1 0.1 1.7e-11 44.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EccE PF11203.8 GAP91929.1 - 0.11 12.8 0.6 0.24 11.7 0.2 1.9 2 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Sulfate_transp PF00916.20 GAP91930.1 - 3.1e-85 286.2 13.6 3.8e-85 285.9 13.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 GAP91930.1 - 5.2e-10 39.0 0.0 9.8e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain YiiD_C PF09500.10 GAP91930.1 - 0.0022 17.9 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Putative thioesterase (yiiD_Cterm) STAS_2 PF13466.6 GAP91930.1 - 0.011 16.0 1.0 0.039 14.3 1.0 2.0 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 GAP91930.1 - 0.88 10.0 13.7 0.1 13.0 3.1 2.7 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Cupin_1 PF00190.22 GAP91931.1 - 1.1e-40 138.8 0.0 4.5e-21 75.0 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 GAP91931.1 - 7.5e-30 102.5 0.9 3.1e-15 55.7 0.4 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 GAP91931.1 - 2.4e-08 34.0 0.2 0.00096 19.1 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 GAP91931.1 - 8.3e-08 31.8 0.1 0.00066 19.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 GAP91931.1 - 0.0048 16.8 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_7 PF12973.7 GAP91931.1 - 0.0093 15.9 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 ChrR Cupin-like domain 3-HAO PF06052.12 GAP91931.1 - 0.024 14.3 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase ARD PF03079.14 GAP91931.1 - 0.03 14.5 0.7 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family DUF1275 PF06912.11 GAP91932.1 - 4.3e-49 167.0 15.9 5.2e-49 166.8 15.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.16 GAP91933.1 - 6.1e-45 153.7 51.9 3.3e-44 151.3 49.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Tmemb_18A PF09771.9 GAP91933.1 - 0.17 12.3 0.3 0.48 10.8 0.3 1.7 1 0 0 1 1 1 0 Transmembrane protein 188 FAD_binding_3 PF01494.19 GAP91936.1 - 3.8e-16 59.3 0.1 9.4e-10 38.3 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 GAP91936.1 - 0.00034 20.8 0.1 0.00075 19.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP91936.1 - 0.00075 18.8 0.1 0.68 9.1 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP91936.1 - 0.0038 16.5 0.2 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP91936.1 - 0.015 15.8 0.1 0.82 10.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP91936.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Epimerase PF01370.21 GAP91937.1 - 5.5e-19 68.6 0.0 6.4e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP91937.1 - 5.1e-09 36.0 0.0 7.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 GAP91937.1 - 3.9e-08 32.7 0.0 5.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 GAP91937.1 - 2.1e-06 27.0 0.0 2.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 GAP91937.1 - 4.5e-05 23.4 0.0 6.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAP91937.1 - 0.00025 20.3 0.1 0.015 14.4 0.0 2.4 1 1 0 2 2 2 1 Male sterility protein adh_short PF00106.25 GAP91937.1 - 0.00051 19.6 0.0 0.00098 18.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase SGL PF08450.12 GAP91938.1 - 3.7e-22 79.1 0.1 8.2e-22 78.0 0.1 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 GAP91938.1 - 0.00035 20.6 0.0 0.0014 18.7 0.0 1.9 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 GAP91938.1 - 0.0009 19.4 0.1 0.02 15.1 0.0 3.0 3 1 1 4 4 4 1 Arylesterase NHL PF01436.21 GAP91938.1 - 0.0035 17.3 0.4 0.12 12.4 0.0 3.2 3 0 0 3 3 3 1 NHL repeat Mucin PF01456.17 GAP91939.1 - 0.015 15.3 20.3 0.017 15.1 20.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Rubella_E2 PF05749.11 GAP91939.1 - 0.5 9.8 10.7 0.59 9.5 10.7 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 SSP160 PF06933.11 GAP91939.1 - 0.76 7.9 19.7 0.79 7.8 19.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TMEM154 PF15102.6 GAP91939.1 - 4.3 7.2 6.5 5.7 6.8 6.5 1.2 1 0 0 1 1 1 0 TMEM154 protein family PhoLip_ATPase_C PF16212.5 GAP91940.1 - 1.3e-66 224.9 11.8 6.5e-66 222.6 12.4 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAP91940.1 - 1.6e-21 75.7 1.1 1.6e-20 72.6 0.0 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GAP91940.1 - 5.2e-12 46.5 0.5 9e-06 26.1 0.1 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 GAP91940.1 - 2.8e-11 43.3 0.0 3.7e-10 39.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 GAP91940.1 - 6.5e-11 42.1 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 GAP91940.1 - 0.0024 17.6 0.1 0.0057 16.4 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fe-ADH PF00465.19 GAP91940.1 - 0.086 11.6 0.2 0.23 10.2 0.0 1.7 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase VPS9 PF02204.18 GAP91941.1 - 6.5e-31 106.6 0.0 1.1e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 GAP91941.1 - 9.3e-17 61.1 0.1 2.1e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 GAP91941.1 - 1.5e-09 37.4 0.1 2.1e-08 33.7 0.0 2.6 2 0 0 2 2 2 1 CUE domain PP1c_bdg PF10488.9 GAP91941.1 - 6.5 6.2 7.1 2.3 7.6 4.2 1.7 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region DHquinase_I PF01487.15 GAP91943.1 - 2.8e-19 70.3 0.0 5.3e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 GAP91943.1 - 2e-17 63.2 0.1 9.3e-17 61.1 0.1 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 GAP91943.1 - 4.2e-15 56.2 0.0 7.6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.20 GAP91943.1 - 3.6e-09 36.8 0.0 7.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 GAP91943.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 GAP91943.1 - 0.016 15.8 0.1 0.044 14.4 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AAA_33 PF13671.6 GAP91943.1 - 0.022 14.9 0.0 0.066 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain ThiF PF00899.21 GAP91943.1 - 0.17 11.2 0.2 0.9 8.8 0.0 2.1 2 0 0 2 2 2 0 ThiF family Zn_clus PF00172.18 GAP91944.1 - 3e-06 27.2 10.3 4.6e-06 26.6 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 GAP91945.1 - 9.6e-06 25.8 3.3 0.0052 17.0 1.2 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acid_PPase PF12689.7 GAP91946.1 - 5.7e-55 185.7 0.0 2.4e-27 95.8 0.0 2.1 2 0 0 2 2 2 2 Acid Phosphatase CRAL_TRIO PF00650.20 GAP91947.1 - 1.1e-24 86.9 0.0 1.8e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAP91947.1 - 2.9e-09 37.0 0.0 6.8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1725 PF08333.11 GAP91947.1 - 0.16 11.6 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Pyr_redox_3 PF13738.6 GAP91948.1 - 1.1e-17 64.3 0.0 2.9e-16 59.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP91948.1 - 5.5e-15 55.4 0.0 2.4e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAP91948.1 - 4.7e-12 45.1 0.8 1.5e-10 40.1 0.2 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAP91948.1 - 8e-11 41.7 0.0 6.3e-08 32.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 GAP91948.1 - 3.9e-05 24.1 0.1 0.59 10.7 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAP91948.1 - 0.00045 19.6 0.0 0.0055 16.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAP91948.1 - 0.002 18.3 0.0 0.027 14.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SnoaL_4 PF13577.6 GAP91948.1 - 0.02 15.0 0.4 0.11 12.6 0.2 2.3 2 1 0 2 2 2 0 SnoaL-like domain Thi4 PF01946.17 GAP91948.1 - 0.02 14.1 0.0 0.2 10.9 0.0 2.3 3 0 0 3 3 3 0 Thi4 family 2-Hacid_dh_C PF02826.19 GAP91948.1 - 0.02 14.2 0.0 0.053 12.9 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UreE_N PF02814.15 GAP91948.1 - 0.11 12.2 0.3 0.8 9.4 0.1 2.2 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain pPIWI_RE_Y PF18156.1 GAP91948.1 - 0.15 12.4 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 pPIWI_RE three-gene island domain Y SSP160 PF06933.11 GAP91949.1 - 0.24 9.5 3.5 0.26 9.4 3.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tannase PF07519.11 GAP91950.1 - 2.6e-71 241.0 7.0 7.5e-52 176.8 3.1 2.1 2 0 0 2 2 2 2 Tannase and feruloyl esterase MFS_1 PF07690.16 GAP91951.1 - 3.9e-46 157.6 26.2 1.7e-45 155.5 25.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily 4HBT_3 PF13622.6 GAP91951.1 - 4.3e-14 53.4 0.9 4.3e-14 53.4 0.9 2.1 2 0 0 2 2 2 1 Thioesterase-like superfamily Sugar_tr PF00083.24 GAP91951.1 - 1.7e-06 27.2 10.8 1.7e-06 27.2 10.8 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Corona_S2 PF01601.16 GAP91951.1 - 2.4 6.5 3.3 3.8 5.9 3.3 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Syntaxin-18_N PF10496.9 GAP91952.1 - 3e-09 37.0 4.2 9.8e-09 35.4 0.3 3.4 3 1 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 GAP91952.1 - 0.0052 16.8 0.0 0.05 13.6 0.0 2.7 4 0 0 4 4 4 1 SNARE domain PI_PP_I PF18363.1 GAP91952.1 - 0.04 14.1 0.2 0.31 11.3 0.0 2.4 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF16 PF01519.16 GAP91952.1 - 0.073 13.6 0.3 0.073 13.6 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function DUF16 DUF4211 PF13926.6 GAP91952.1 - 0.1 12.7 1.4 1.3 9.1 0.0 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4211) Plk4_PB2 PF18409.1 GAP91952.1 - 0.11 13.2 4.3 6.3 7.5 0.2 3.3 3 1 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 APG6_N PF17675.1 GAP91952.1 - 8.8 6.9 12.9 0.43 11.1 1.8 2.8 3 1 0 3 3 3 0 Apg6 coiled-coil region Aminotran_1_2 PF00155.21 GAP91953.1 - 8.1e-86 288.4 0.0 9.3e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Polysacc_deac_1 PF01522.21 GAP91954.1 - 1.7e-14 53.8 0.0 3.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 GAP91954.1 - 0.058 13.0 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF2785 PF10978.8 GAP91955.1 - 0.0021 17.9 0.1 0.0051 16.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2785) 4HBT PF03061.22 GAP91956.1 - 0.08 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily AlaDh_PNT_N PF05222.15 GAP91957.1 - 4.3e-23 82.1 0.0 6e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF773 PF05600.12 GAP91959.1 - 0.013 14.3 0.8 0.019 13.7 0.8 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 ADIP PF11559.8 GAP91959.1 - 0.066 13.3 3.5 0.14 12.2 3.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MPS2 PF17060.5 GAP91959.1 - 0.7 9.1 4.4 1.1 8.4 4.4 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Med21 PF11221.8 GAP91959.1 - 5.6 7.2 10.1 0.36 11.1 4.8 1.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex AIG1 PF04548.16 GAP91960.1 - 2.3e-10 40.2 0.0 4.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 GAP91960.1 - 9e-08 32.2 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 GAP91960.1 - 6.6e-06 26.3 5.5 0.0032 17.5 0.1 3.1 2 2 1 3 3 3 2 Dynamin family SRPRB PF09439.10 GAP91960.1 - 0.0012 18.3 0.0 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 GAP91960.1 - 0.0015 18.5 0.2 0.0048 16.8 0.2 1.7 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 GAP91960.1 - 0.0043 17.4 1.4 0.021 15.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 GAP91960.1 - 0.014 15.5 0.7 0.081 13.0 0.0 2.2 2 1 0 2 2 2 0 Helicase HerA, central domain Septin PF00735.18 GAP91960.1 - 0.023 14.0 0.1 0.093 12.0 0.0 2.0 2 1 0 2 2 2 0 Septin AAA_22 PF13401.6 GAP91960.1 - 0.028 14.7 0.2 0.11 12.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAP91960.1 - 0.064 13.7 0.7 21 5.5 1.5 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 GAP91960.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 GAP91960.1 - 0.1 13.1 0.5 0.61 10.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 GAP91960.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 GAP91960.1 - 0.14 11.2 0.1 0.34 9.9 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Viral_helicase1 PF01443.18 GAP91960.1 - 0.15 11.7 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF1640 PF07798.11 GAP91960.1 - 0.52 10.3 5.2 0.84 9.7 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FOXP-CC PF16159.5 GAP91960.1 - 0.55 10.9 3.3 9.4 6.9 1.4 2.5 2 1 0 2 2 2 0 FOXP coiled-coil domain HSP70 PF00012.20 GAP91961.1 - 1.1e-05 23.8 1.0 0.00038 18.8 1.0 2.8 1 1 0 1 1 1 1 Hsp70 protein Pyrid_oxidase_2 PF13883.6 GAP91961.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase SET PF00856.28 GAP91962.1 - 2.4e-08 34.5 0.3 1.2e-07 32.3 0.0 2.3 2 1 0 2 2 2 1 SET domain TPR_16 PF13432.6 GAP91962.1 - 2.3e-06 28.2 3.3 0.0056 17.3 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAP91962.1 - 5.3e-05 23.0 0.6 0.11 12.7 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 GAP91962.1 - 0.0022 18.5 0.4 0.019 15.6 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Bud13 PF09736.9 GAP91963.1 - 5.3e-43 146.9 0.3 5.3e-43 146.9 0.3 1.7 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex TFIIF_alpha PF05793.12 GAP91964.1 - 0.015 13.9 56.5 0.059 12.0 53.7 3.2 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.19 GAP91965.1 - 3.8e-19 68.6 0.0 3.9e-12 46.2 0.0 2.7 2 0 0 2 2 2 2 Cid1 family poly A polymerase Churchill PF06573.11 GAP91965.1 - 0.0079 16.5 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 Churchill protein NTP_transf_2 PF01909.23 GAP91965.1 - 0.031 14.6 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain XPG_I_2 PF12813.7 GAP91966.1 - 7.2e-46 156.7 0.0 2.5e-45 154.9 0.0 1.8 2 0 0 2 2 2 1 XPG domain containing Pribosyltran_N PF13793.6 GAP91967.1 - 3.9e-41 139.6 0.0 8.4e-41 138.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 GAP91967.1 - 1.7e-34 119.5 0.0 2.3e-29 102.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 GAP91967.1 - 1.5e-09 37.6 0.1 1.1e-05 25.0 0.0 2.7 3 0 0 3 3 3 2 Phosphoribosyl transferase domain UPRTase PF14681.6 GAP91967.1 - 0.045 13.2 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase zf-C3HC4_3 PF13920.6 GAP91969.1 - 4.8e-08 32.7 13.4 8.3e-08 32.0 13.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAP91969.1 - 0.13 12.2 13.3 0.22 11.4 13.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RNase_PH PF01138.21 GAP91970.1 - 2e-27 96.3 0.0 3.2e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 adh_short PF00106.25 GAP91971.1 - 3.8e-51 173.3 0.1 5.2e-51 172.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP91971.1 - 7.4e-35 120.6 0.3 9.4e-35 120.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP91971.1 - 1.2e-11 44.8 0.1 1.9e-11 44.2 0.1 1.3 1 1 0 1 1 1 1 KR domain Abhydrolase_3 PF07859.13 GAP91972.1 - 3.3e-42 144.7 0.0 4.7e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAP91972.1 - 1.2e-05 24.4 0.0 2.7e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 GAP91972.1 - 9.8e-05 23.1 5.9 9.8e-05 23.1 5.9 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 GAP91972.1 - 0.0017 18.2 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 GAP91972.1 - 0.0043 16.6 0.0 0.17 11.4 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 GAP91972.1 - 0.032 13.7 0.1 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase TPR_12 PF13424.6 GAP91973.1 - 4.4e-18 65.4 8.3 1.4e-08 34.9 0.3 5.0 3 1 1 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.22 GAP91973.1 - 6.7e-13 48.4 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 GAP91973.1 - 3e-09 36.5 0.8 0.012 15.5 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 GAP91973.1 - 9.2e-06 25.4 16.6 0.17 12.0 0.1 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP91973.1 - 6.2e-05 22.9 13.1 0.3 11.4 0.1 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 GAP91973.1 - 0.00021 20.8 0.2 0.032 13.6 0.0 2.5 2 0 0 2 2 2 1 MalT-like TPR region TPR_1 PF00515.28 GAP91973.1 - 0.00048 19.8 12.6 1.1 9.2 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 GAP91973.1 - 0.00049 20.5 0.1 0.0031 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP91973.1 - 0.011 16.0 0.0 0.054 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain TPR_7 PF13176.6 GAP91973.1 - 0.019 15.0 5.8 19 5.5 0.0 5.8 6 1 1 7 7 6 0 Tetratricopeptide repeat SPO22 PF08631.10 GAP91973.1 - 0.032 13.7 11.4 0.036 13.6 0.1 3.2 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 GAP91973.1 - 1.9 9.5 6.5 29 5.8 0.1 5.1 4 1 0 4 4 3 0 Tetratricopeptide repeat Peptidase_M1 PF01433.20 GAP91974.1 - 2.4e-78 262.7 0.1 3.6e-78 262.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 GAP91974.1 - 7.2e-67 226.2 0.1 1e-66 225.7 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 GAP91974.1 - 1.2e-47 162.5 0.0 1.3e-46 159.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Beta-lactamase PF00144.24 GAP91975.1 - 2.3e-17 63.3 0.0 1.3e-16 60.8 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase ketoacyl-synt PF00109.26 GAP91976.1 - 2.3e-58 197.7 0.0 5e-58 196.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 GAP91976.1 - 1.8e-53 181.7 0.0 2.7e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 GAP91976.1 - 3.4e-49 167.2 1.0 7.7e-49 166.0 1.0 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 GAP91976.1 - 1.1e-37 130.3 0.0 1.7e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP91976.1 - 1.3e-32 112.3 0.3 8.1e-32 109.7 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 GAP91976.1 - 1.2e-17 65.2 0.0 4.9e-17 63.2 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 GAP91976.1 - 1.8e-15 57.3 0.0 3.8e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 GAP91976.1 - 2e-11 44.0 0.3 7.2e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 GAP91976.1 - 2.8e-08 34.0 0.1 6e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 GAP91976.1 - 1.3e-05 25.1 1.0 2.9e-05 23.9 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 GAP91976.1 - 3.6e-05 23.6 0.0 0.00058 19.7 0.0 2.7 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis adh_short PF00106.25 GAP91976.1 - 0.00012 21.6 0.8 0.00012 21.6 0.8 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Hydrolase_4 PF12146.8 GAP91977.1 - 2.3e-10 40.1 0.0 3.6e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 GAP91977.1 - 9e-07 29.7 0.1 1.9e-06 28.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 GAP91977.1 - 1.2e-06 28.1 0.0 0.0048 16.4 0.0 2.0 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAP91977.1 - 2.5e-06 27.3 0.0 0.0048 16.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 GAP91977.1 - 2e-05 24.3 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 GAP91977.1 - 0.00048 18.9 0.0 1.3 7.6 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) FAD_binding_4 PF01565.23 GAP91978.1 - 2.2e-18 66.3 1.1 3.9e-18 65.5 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP91978.1 - 2.1e-11 43.7 0.9 2.1e-11 43.7 0.9 1.9 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 GAP91978.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding p450 PF00067.22 GAP91979.1 - 1.9e-61 208.2 0.0 2.4e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 GAP91982.1 - 2.7e-33 115.1 0.0 3.7e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP91982.1 - 4.8e-22 78.7 0.6 9.2e-22 77.7 0.6 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAP91982.1 - 4.6e-08 32.8 0.0 1.7e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 GAP91982.1 - 0.0019 17.7 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Serglycin PF04360.12 GAP91982.1 - 0.0081 16.1 0.9 1.4 8.9 0.0 2.2 2 0 0 2 2 2 2 Serglycin RmlD_sub_bind PF04321.17 GAP91982.1 - 0.051 12.7 0.2 0.14 11.2 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 GAP91982.1 - 0.071 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 GAP91982.1 - 0.14 12.7 0.0 0.32 11.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ank_2 PF12796.7 GAP91983.1 - 4.4e-19 68.8 0.0 1.5e-10 41.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP91983.1 - 5.8e-18 64.7 0.0 3.5e-11 43.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAP91983.1 - 1e-17 64.2 0.6 2.4e-10 40.8 0.0 3.1 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP91983.1 - 1.6e-15 55.7 0.4 0.00036 20.8 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 GAP91983.1 - 1.9e-13 50.2 0.5 0.00015 22.0 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat bZIP_1 PF00170.21 GAP91983.1 - 0.015 15.4 7.2 0.024 14.7 7.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 GAP91983.1 - 0.026 14.6 5.1 0.044 13.9 5.1 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Abhydrolase_6 PF12697.7 GAP91984.1 - 6.5e-06 26.9 6.6 7.3e-06 26.7 6.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP91984.1 - 0.028 13.7 0.3 0.032 13.5 0.3 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 tRNA_int_endo PF01974.17 GAP91986.1 - 3.3e-12 46.3 0.0 8e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF3575 PF12099.8 GAP91986.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) PAXNEB PF05625.11 GAP91987.1 - 6.6e-102 341.4 0.0 7.4e-102 341.2 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.15 GAP91988.1 - 4e-41 140.5 0.0 4.5e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 GAP91988.1 - 0.00065 19.8 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G NUDIX PF00293.28 GAP91989.1 - 2e-11 44.0 0.1 4.9e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain DUF4743 PF15916.5 GAP91989.1 - 7.3e-10 38.9 0.1 1.1e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) MIF4G_like_2 PF09090.11 GAP91989.1 - 0.12 11.8 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 MIF4G like DUF775 PF05603.12 GAP91990.1 - 1.1e-54 185.0 0.0 1.3e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) GDA1_CD39 PF01150.17 GAP91991.1 - 5.3e-107 358.1 0.0 7.3e-107 357.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Amidoligase_2 PF12224.8 GAP91992.1 - 5.5e-16 59.0 0.0 2.5e-10 40.5 0.0 2.9 3 0 0 3 3 3 2 Putative amidoligase enzyme HET PF06985.11 GAP91993.1 - 8.7e-34 117.0 0.7 1.7e-33 116.0 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1706 PF08020.11 GAP91993.1 - 0.12 12.2 0.2 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) AA_permease PF00324.21 GAP91994.1 - 3e-133 444.9 46.3 3.7e-133 444.6 46.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP91994.1 - 4.1e-34 118.1 52.5 5.9e-34 117.6 52.5 1.2 1 0 0 1 1 1 1 Amino acid permease HET PF06985.11 GAP91995.1 - 0.00049 20.5 0.7 0.0011 19.4 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) His_Phos_1 PF00300.22 GAP91996.1 - 1e-31 110.2 0.0 1.4e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) p450 PF00067.22 GAP91997.1 - 1.7e-21 76.5 0.0 2.3e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Isochorismatase PF00857.20 GAP91998.1 - 7.7e-18 65.3 0.0 9.1e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family GMC_oxred_N PF00732.19 GAP91999.1 - 2.2e-47 161.9 0.0 3e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP91999.1 - 1.3e-37 129.5 0.0 2.6e-37 128.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase PhyH PF05721.13 GAP91999.1 - 7.8e-24 85.1 0.0 1.3e-23 84.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DAO PF01266.24 GAP91999.1 - 6.7e-06 25.9 0.7 0.00065 19.4 0.2 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP91999.1 - 8.6e-05 21.8 0.1 0.0072 15.4 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAP91999.1 - 0.00022 21.4 0.4 0.0008 19.6 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 GAP91999.1 - 0.00064 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAP91999.1 - 0.0075 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP91999.1 - 0.0097 15.2 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP91999.1 - 0.052 12.2 0.0 0.16 10.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 GAP92000.1 - 8.3e-37 126.9 51.5 1.8e-36 125.8 49.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP92000.1 - 1e-14 53.9 6.2 2e-14 53.0 6.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP92000.1 - 1.3e-07 30.8 6.7 1.3e-07 30.8 6.7 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter DUF3597 PF12200.8 GAP92000.1 - 0.15 12.6 0.2 0.29 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) MASE3 PF17159.4 GAP92000.1 - 0.42 10.2 6.9 0.27 10.8 0.9 2.7 2 1 1 3 3 3 0 Membrane-associated sensor domain DUF3235 PF11574.8 GAP92000.1 - 0.63 10.9 2.8 1.2 10.1 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Phage_holin_5_1 PF06946.11 GAP92000.1 - 3.3 8.1 11.2 0.11 12.9 0.8 3.3 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 DPPIV_N PF00930.21 GAP92005.1 - 5.8e-107 357.5 0.1 7.9e-107 357.1 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 GAP92005.1 - 1.5e-55 188.0 3.8 2.6e-55 187.2 3.8 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 GAP92005.1 - 2.7e-06 27.2 3.2 4e-05 23.3 1.8 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 GAP92005.1 - 0.014 16.0 0.0 0.13 12.8 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family YbjQ_1 PF01906.17 GAP92006.1 - 5e-28 97.8 0.2 5.7e-28 97.6 0.2 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding GH131_N PF18271.1 GAP92008.1 - 1.3e-79 267.5 0.4 1.6e-79 267.3 0.4 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 GAP92008.1 - 0.054 13.3 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Cullin PF00888.22 GAP92011.1 - 2e-191 637.8 0.1 2e-191 637.8 0.1 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 GAP92011.1 - 2.2e-25 88.5 1.0 8.4e-25 86.6 1.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain TetR_C_29 PF17938.1 GAP92011.1 - 0.088 12.9 0.0 0.47 10.5 0.0 2.3 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DFF-C PF09033.10 GAP92011.1 - 0.11 12.4 0.9 0.45 10.4 0.5 2.1 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain RPA_C PF08784.11 GAP92011.1 - 0.14 12.8 0.0 0.44 11.2 0.0 1.9 1 0 0 1 1 1 0 Replication protein A C terminal DUF4326 PF14216.6 GAP92011.1 - 0.27 12.0 1.3 0.61 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) zf-DNL PF05180.12 GAP92012.1 - 2.1e-26 91.7 0.1 3.4e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 GAP92012.1 - 0.0086 15.8 0.3 0.015 15.0 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger Zn_ribbon_SprT PF17283.2 GAP92012.1 - 0.78 9.7 4.9 6.8 6.7 5.2 2.1 1 1 1 2 2 2 0 SprT-like zinc ribbon domain DRIM PF07539.12 GAP92013.1 - 3.5e-178 593.8 0.0 1.5e-177 591.7 0.0 2.2 1 0 0 1 1 1 1 Down-regulated in metastasis Tti2 PF10521.9 GAP92013.1 - 0.016 14.7 1.3 16 4.9 0.0 4.5 4 1 1 5 5 5 0 Tti2 family DUF3385 PF11865.8 GAP92013.1 - 0.017 15.1 0.3 10 6.0 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) HEAT PF02985.22 GAP92013.1 - 0.22 11.9 5.0 25 5.5 0.1 6.3 5 1 1 6 6 6 0 HEAT repeat CwfJ_C_1 PF04677.15 GAP92015.1 - 2.3e-20 72.7 0.0 4.5e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 GAP92015.1 - 2.7e-15 57.0 1.8 2.8e-15 57.0 0.4 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 DNA_pol_phi PF04931.13 GAP92016.1 - 8.7e-187 622.7 13.1 8.7e-187 622.7 13.1 1.5 2 0 0 2 2 2 1 DNA polymerase phi SAM_KSR1 PF13543.6 GAP92016.1 - 0.04 14.1 0.1 0.099 12.8 0.1 1.6 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 DUF1676 PF07898.13 GAP92016.1 - 0.23 11.5 3.9 0.69 9.9 3.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) RRM_1 PF00076.22 GAP92017.1 - 0.00081 19.2 0.0 0.0025 17.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans_2 PF11951.8 GAP92019.1 - 3.6e-08 32.6 0.2 8.1e-08 31.5 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP92019.1 - 1.2e-06 28.5 10.1 2.2e-06 27.7 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4088 PF13317.6 GAP92020.1 - 0.023 14.3 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) Ferrochelatase PF00762.19 GAP92021.1 - 0.082 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Ferrochelatase Chromo PF00385.24 GAP92022.1 - 1.1e-05 25.2 1.5 2.1e-05 24.3 0.7 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.19 GAP92022.1 - 1.5 8.9 9.0 0.43 10.6 2.8 2.9 2 0 0 2 2 2 0 AT hook motif Proteasome PF00227.26 GAP92023.1 - 2.6e-43 147.7 2.1 5.1e-30 104.4 0.0 2.8 2 1 1 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 GAP92023.1 - 2.3e-11 43.2 0.0 4.4e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ANAPC9 PF12856.7 GAP92023.1 - 1.5 9.0 5.9 2.7 8.2 5.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 NOA36 PF06524.12 GAP92023.1 - 3 7.1 6.6 3.8 6.8 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein Rhodanese PF00581.20 GAP92024.1 - 6e-13 49.2 0.0 1.4e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Glyco_hydro_16 PF00722.21 GAP92025.1 - 2.9e-10 39.9 2.7 5.4e-10 39.0 2.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CBM_1 PF00734.18 GAP92025.1 - 2.7e-09 36.8 16.1 2.7e-09 36.8 16.1 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Dynamin_N PF00350.23 GAP92026.1 - 3.4e-15 56.5 1.9 9.4e-15 55.1 0.0 2.7 3 1 0 3 3 1 1 Dynamin family MMR_HSR1 PF01926.23 GAP92026.1 - 8.1e-06 25.9 0.0 0.00014 21.9 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF4164 PF13747.6 GAP92026.1 - 0.00024 21.3 1.8 0.00024 21.3 1.8 4.0 5 0 0 5 5 4 1 Domain of unknown function (DUF4164) ABC_tran PF00005.27 GAP92026.1 - 0.00059 20.4 1.2 0.0027 18.2 0.0 2.7 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 GAP92026.1 - 0.0015 18.5 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 GAP92026.1 - 0.04 14.2 0.4 0.69 10.2 0.0 3.1 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 GAP92026.1 - 0.048 13.0 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 AIG1 family IIGP PF05049.13 GAP92026.1 - 0.061 12.4 0.6 0.24 10.4 0.0 2.3 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) AAA_21 PF13304.6 GAP92026.1 - 0.076 12.8 0.2 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 GAP92026.1 - 0.077 12.0 0.9 0.81 8.6 0.1 2.7 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4407 PF14362.6 GAP92026.1 - 0.22 10.8 0.0 0.22 10.8 0.0 3.2 2 1 1 3 3 2 0 Domain of unknown function (DUF4407) AAA_16 PF13191.6 GAP92026.1 - 0.24 11.8 0.0 0.24 11.8 0.0 3.7 3 1 1 4 4 4 0 AAA ATPase domain E2F_CC-MB PF16421.5 GAP92026.1 - 0.24 11.8 3.6 9.6 6.7 0.2 4.0 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain Mfp-3 PF04202.13 GAP92026.1 - 0.26 11.7 1.1 0.71 10.3 1.1 1.7 1 0 0 1 1 1 0 Foot protein 3 Tropomyosin_1 PF12718.7 GAP92026.1 - 0.54 10.4 16.4 1.3 9.2 1.4 3.9 3 0 0 3 3 3 0 Tropomyosin like AAA_23 PF13476.6 GAP92026.1 - 0.65 10.5 0.0 0.65 10.5 0.0 3.9 2 1 1 3 3 1 0 AAA domain DUF4600 PF15372.6 GAP92026.1 - 0.81 10.1 15.3 3.1 8.2 0.4 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4600) KASH_CCD PF14662.6 GAP92026.1 - 0.91 9.3 21.9 0.17 11.7 3.8 3.5 2 2 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 GAP92026.1 - 1.1 9.3 21.6 0.99 9.4 2.7 4.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.13 GAP92026.1 - 2.7 8.4 7.9 18 5.8 0.0 4.8 5 0 0 5 5 4 0 Lipoprotein leucine-zipper DUF2968 PF11180.8 GAP92026.1 - 4.4 6.9 17.9 0.046 13.3 1.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) DegS PF05384.11 GAP92026.1 - 4.6 6.7 14.1 0.068 12.7 0.4 3.5 3 0 0 3 3 3 0 Sensor protein DegS DUF4140 PF13600.6 GAP92026.1 - 5.4 7.5 11.7 12 6.4 0.7 3.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) SAS4 PF15460.6 GAP92026.1 - 6 7.0 11.6 3.2 7.9 1.2 4.0 4 0 0 4 4 4 0 Something about silencing, SAS, complex subunit 4 Jnk-SapK_ap_N PF09744.9 GAP92026.1 - 9.7 6.4 19.8 0.17 12.1 2.1 3.8 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF4307 PF14155.6 GAP92027.1 - 1.3 8.9 4.2 3.2 7.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Phage_holin_3_6 PF07332.11 GAP92027.1 - 2.2 8.4 7.3 12 6.0 7.3 2.1 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III RRM_1 PF00076.22 GAP92028.1 - 9.6e-49 163.1 0.0 1.5e-16 59.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAP92028.1 - 1.2e-05 25.2 0.0 0.0025 17.8 0.1 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 GAP92028.1 - 2.5e-05 24.2 0.0 0.0019 18.2 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 GAP92028.1 - 0.00045 20.3 0.1 0.058 13.5 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 GAP92028.1 - 0.0015 18.3 0.0 0.057 13.3 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 GAP92028.1 - 0.015 14.9 0.0 0.049 13.2 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TauD PF02668.16 GAP92031.1 - 1.7e-59 201.9 2.4 2.3e-59 201.4 2.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NMD3 PF04981.13 GAP92032.1 - 1.2e-65 221.4 1.1 1.8e-65 220.8 1.1 1.3 1 0 0 1 1 1 1 NMD3 family HypA PF01155.19 GAP92032.1 - 0.034 14.2 1.2 5.1 7.1 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_6 PF14599.6 GAP92032.1 - 0.079 13.0 4.0 1.3 9.1 0.7 2.9 2 1 0 2 2 2 0 Zinc-ribbon DZR PF12773.7 GAP92032.1 - 0.082 13.0 1.2 1.2 9.2 0.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon Trypsin PF00089.26 GAP92033.1 - 2.7e-06 27.3 0.0 6.6e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAP92033.1 - 1.3e-05 26.2 0.0 2.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_M35 PF02102.15 GAP92034.1 - 1.3e-66 225.0 9.9 1.4e-66 224.8 9.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 GAP92034.1 - 1.6e-33 116.3 3.4 2.9e-33 115.5 3.4 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase NPCBM_assoc PF10633.9 GAP92034.1 - 0.085 13.1 2.3 1 9.7 0.0 2.7 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF4232 PF14016.6 GAP92035.1 - 0.0065 16.6 3.2 0.028 14.6 3.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4232) Glyco_hydro_76 PF03663.14 GAP92036.1 - 3.6e-145 484.1 8.1 4.5e-145 483.8 8.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Aminotran_1_2 PF00155.21 GAP92036.1 - 3.1e-42 145.1 0.0 3.7e-34 118.5 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II Glyco_hydro_88 PF07470.13 GAP92036.1 - 1.8 7.5 5.1 1.5 7.8 0.2 2.6 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Tankyrase_bdg_C PF15327.6 GAP92037.1 - 0.028 14.9 1.0 0.032 14.7 1.0 1.3 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain SUIM_assoc PF16619.5 GAP92038.1 - 0.00022 21.2 14.4 0.022 14.8 0.3 2.9 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 GAP92038.1 - 0.097 12.3 12.1 0.35 10.5 2.7 2.3 2 0 0 2 2 2 0 Spt20 family Roughex PF06020.11 GAP92038.1 - 0.11 11.5 5.9 0.46 9.5 0.2 2.3 2 0 0 2 2 2 0 Drosophila roughex protein ANAPC_CDC26 PF10471.9 GAP92038.1 - 0.34 11.8 14.3 0.58 11.0 1.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Beta-lactamase PF00144.24 GAP92040.1 - 2.1e-44 152.1 0.0 3.5e-44 151.4 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 GAP92040.1 - 1.1e-15 57.9 0.0 2.7e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Ank_2 PF12796.7 GAP92041.1 - 1.9e-05 25.1 0.1 2.5 8.8 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP92041.1 - 0.0022 18.4 0.8 1.1e+02 3.9 0.0 5.5 5 0 0 5 5 5 0 Ankyrin repeat DUF2119 PF09892.9 GAP92041.1 - 0.017 14.6 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) NACHT PF05729.12 GAP92041.1 - 0.017 15.0 0.1 0.088 12.7 0.1 2.2 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 GAP92041.1 - 0.16 12.4 0.3 2.6 8.4 0.1 2.7 2 0 0 2 2 2 0 AAA ATPase domain ORC6 PF05460.13 GAP92042.1 - 1.2 8.4 6.7 2 7.6 6.7 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hydrolase_4 PF12146.8 GAP92044.1 - 8.2e-14 51.4 1.2 4.5e-13 49.0 0.1 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP92044.1 - 5.4e-10 39.3 0.0 6.9e-09 35.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP92044.1 - 6e-09 36.8 6.5 6e-09 36.8 6.5 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 GAP92044.1 - 0.015 15.3 0.0 4.5 7.1 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 GAP92044.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 GAP92044.1 - 0.14 11.7 0.1 0.49 9.9 0.1 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 GAP92044.1 - 0.25 11.0 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Aldo_ket_red PF00248.21 GAP92045.1 - 7e-53 179.7 0.0 8e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF202 PF02656.15 GAP92046.1 - 1.7e-21 76.4 0.9 1.7e-21 76.4 0.9 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF202) DUF2975 PF11188.8 GAP92046.1 - 0.026 14.4 0.1 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Rax2 PF12768.7 GAP92046.1 - 0.12 11.9 0.6 0.19 11.2 0.6 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity AAA_11 PF13086.6 GAP92047.1 - 8.2e-59 199.5 0.0 1.7e-58 198.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 GAP92047.1 - 3.1e-56 190.1 0.0 2.1e-55 187.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAP92047.1 - 4.2e-12 46.2 0.0 7.8e-11 42.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAP92047.1 - 7.8e-08 32.8 0.0 4.9e-07 30.2 0.0 2.4 3 1 0 3 3 2 1 AAA domain DUF2075 PF09848.9 GAP92047.1 - 6.1e-07 29.0 0.1 3.4e-06 26.6 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 GAP92047.1 - 1.6e-06 28.1 0.0 0.21 11.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 GAP92047.1 - 9.7e-05 22.4 0.0 0.00026 21.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 GAP92047.1 - 0.00038 20.1 0.6 0.076 12.6 0.0 3.6 2 1 1 4 4 4 1 AAA domain AAA_16 PF13191.6 GAP92047.1 - 0.0011 19.4 0.0 0.0036 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP92047.1 - 0.0012 19.1 0.2 0.023 15.0 0.2 2.6 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 GAP92047.1 - 0.0034 17.0 0.0 0.012 15.2 0.0 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 GAP92047.1 - 0.0049 17.3 0.0 0.053 13.9 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 GAP92047.1 - 0.0095 15.9 0.0 0.055 13.4 0.0 2.3 2 0 0 2 2 2 1 Flavivirus DEAD domain T2SSE PF00437.20 GAP92047.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 GAP92047.1 - 0.02 14.4 0.0 0.77 9.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein UvrD_C_2 PF13538.6 GAP92047.1 - 0.04 13.8 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain TrwB_AAD_bind PF10412.9 GAP92047.1 - 0.05 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain UvrD_C PF13361.6 GAP92047.1 - 0.058 12.8 0.0 4.1 6.7 0.0 2.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 GAP92047.1 - 0.069 12.3 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase cobW PF02492.19 GAP92047.1 - 0.075 12.6 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 GAP92047.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 GAP92047.1 - 0.15 11.7 0.1 0.9 9.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain Peptidase_M28 PF04389.17 GAP92049.1 - 3.6e-30 105.1 0.0 8.9e-30 103.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAP92049.1 - 7.8e-07 29.0 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 fn3 PF00041.21 GAP92049.1 - 0.0078 16.5 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Peptidase_M42 PF05343.14 GAP92049.1 - 0.018 14.1 0.0 0.06 12.4 0.0 1.8 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase BBE PF08031.12 GAP92050.1 - 4.8e-11 42.6 0.1 1.2e-10 41.3 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 GAP92050.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.23 GAP92051.1 - 1.5e-21 76.6 1.7 2.2e-21 76.1 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain DSPn PF14671.6 GAP92052.1 - 1.4e-41 142.3 0.0 3.8e-39 134.3 0.0 2.7 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 GAP92052.1 - 4.7e-16 58.8 0.0 8.8e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAP92052.1 - 4.3e-06 26.5 0.2 1.5e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAP92052.1 - 0.057 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Pcc1 PF09341.10 GAP92053.1 - 2.8e-31 107.5 1.5 3.5e-31 107.1 1.5 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 WW PF00397.26 GAP92054.1 - 9.4e-12 44.8 0.2 3.4e-11 43.0 0.2 2.1 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 GAP92054.1 - 0.00012 21.2 6.9 0.00089 18.4 0.0 3.0 3 0 0 3 3 3 2 PhoD-like phosphatase SPICE PF15678.5 GAP92054.1 - 0.56 9.5 7.5 1.2 8.4 7.5 1.4 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression PMM PF03332.13 GAP92055.1 - 3.8e-99 330.9 0.0 4.4e-99 330.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.13 GAP92055.1 - 0.014 14.9 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 GAP92055.1 - 0.034 13.9 0.0 6.8 6.3 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAP92055.1 - 0.12 12.7 0.0 5.1 7.5 0.0 2.8 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Na_Ca_ex PF01699.24 GAP92057.1 - 1.4e-45 154.9 48.3 3.8e-25 88.6 18.7 3.3 3 1 1 4 4 4 2 Sodium/calcium exchanger protein SPC12 PF06645.13 GAP92057.1 - 0.0062 16.6 0.4 0.0062 16.6 0.4 4.3 4 0 0 4 4 4 2 Microsomal signal peptidase 12 kDa subunit (SPC12) CHCH PF06747.13 GAP92058.1 - 4e-06 26.8 2.0 6.9e-06 26.0 1.7 1.6 1 1 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 GAP92058.1 - 0.00056 20.1 2.8 0.0008 19.6 2.8 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 GAP92058.1 - 0.0062 16.8 2.3 0.0096 16.2 2.0 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 WBS_methylT PF12589.8 GAP92058.1 - 0.13 13.0 4.1 0.21 12.4 4.1 1.4 1 1 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome NatB_MDM20 PF09797.9 GAP92059.1 - 1.1e-31 110.2 0.0 2e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 GAP92059.1 - 0.0071 16.8 0.0 0.89 10.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Ilm1 PF10311.9 GAP92060.1 - 4.3e-51 172.8 0.2 4.9e-51 172.7 0.2 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 TadE PF07811.12 GAP92060.1 - 4.3 7.7 8.4 0.25 11.6 1.5 2.4 2 0 0 2 2 2 0 TadE-like protein Prenyltrans PF00432.21 GAP92061.1 - 8.2e-40 134.2 0.5 1e-08 34.8 0.0 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 GAP92061.1 - 0.061 12.4 0.0 0.16 11.0 0.0 1.7 1 1 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain TRAPPC10 PF12584.8 GAP92062.1 - 3.4e-29 101.6 0.0 7.1e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 GAP92062.1 - 0.03 13.9 0.8 0.051 13.2 0.8 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 IF-2B PF01008.17 GAP92063.1 - 3.5e-56 190.5 0.1 4.6e-54 183.5 0.1 2.0 1 1 0 1 1 1 1 Initiation factor 2 subunit family M20_dimer PF07687.14 GAP92064.1 - 9.6e-17 60.9 0.0 1.6e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 GAP92064.1 - 1.5e-12 47.7 7.6 5.4e-12 45.8 7.6 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 GAP92064.1 - 0.00026 20.7 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 THB PF18362.1 GAP92064.1 - 0.031 13.9 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Tri-helix bundle domain Pkinase PF00069.25 GAP92065.1 - 3.7e-66 223.2 0.0 5e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92065.1 - 3.5e-41 141.2 0.0 7.2e-40 136.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP92065.1 - 6.3e-07 29.0 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAP92065.1 - 6.9e-05 22.0 0.0 0.00016 20.7 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 GAP92065.1 - 0.006 16.5 2.5 0.041 13.8 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 GAP92065.1 - 0.025 14.0 0.1 0.079 12.3 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAP92065.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 GAP92065.1 - 0.18 11.4 0.5 0.56 9.8 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase p450 PF00067.22 GAP92066.1 - 1.2e-65 222.0 0.0 1.7e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 GAP92068.1 - 4.5e-39 132.3 3.0 9.8e-17 60.7 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Trypsin PF00089.26 GAP92069.1 - 1.3e-09 38.2 0.1 4.9e-09 36.3 0.1 1.8 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 GAP92069.1 - 1.6e-08 35.6 0.0 2.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C3 PF00548.20 GAP92069.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) OmdA PF13376.6 GAP92070.1 - 1.3e-16 60.3 1.5 1.5e-16 60.2 0.3 1.7 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated SWIB PF02201.18 GAP92071.1 - 3.2e-31 107.0 0.9 1.3e-30 105.1 0.2 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 GAP92071.1 - 6.7e-14 51.6 2.0 7.3e-14 51.4 0.8 1.7 2 0 0 2 2 2 1 DEK C terminal domain zf-C3HC4_3 PF13920.6 GAP92072.1 - 5.8e-05 22.9 11.0 5.8e-05 22.9 11.0 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SMG1 PF15785.5 GAP92072.1 - 0.12 10.8 0.2 0.18 10.1 0.2 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 Pkinase PF00069.25 GAP92073.1 - 3.3e-24 85.7 0.0 6.3e-24 84.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92073.1 - 4.6e-11 42.5 0.0 1.8e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP92073.1 - 0.013 15.4 0.3 0.026 14.5 0.1 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ag332 PF04671.12 GAP92073.1 - 0.065 13.2 0.7 0.12 12.3 0.7 1.4 1 0 0 1 1 1 0 Erythrocyte membrane-associated giant protein antigen 332 Kdo PF06293.14 GAP92073.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 GAP92074.1 - 3.2e-43 148.0 0.0 4.1e-41 141.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 GAP92074.1 - 1.2e-39 135.4 0.0 3e-39 134.1 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 GAP92074.1 - 1.8e-23 83.1 0.0 1.4e-21 77.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 GAP92074.1 - 2.9e-07 30.1 0.7 0.00019 21.2 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 GAP92074.1 - 0.00067 19.3 0.2 0.02 14.5 0.1 2.2 1 1 1 2 2 2 1 PQQ-like domain Pkinase_fungal PF17667.1 GAP92074.1 - 0.002 17.0 0.0 0.0039 16.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAP92074.1 - 0.0099 15.8 0.1 0.025 14.5 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 GAP92074.1 - 0.034 13.5 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 GAP92074.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Trypsin_2 PF13365.6 GAP92074.1 - 0.14 13.1 0.0 0.32 11.9 0.0 1.7 1 0 0 1 1 1 0 Trypsin-like peptidase domain FA_desaturase PF00487.24 GAP92076.1 - 1.1e-25 91.0 14.8 2.4e-25 89.8 14.8 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 GAP92076.1 - 1e-05 25.8 0.0 2.8e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Arteri_Gl PF00951.18 GAP92076.1 - 0.021 14.7 0.3 0.038 13.8 0.3 1.5 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein RabGAP-TBC PF00566.18 GAP92077.1 - 2e-26 93.0 0.0 4.6e-26 91.8 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SBE2 PF17076.5 GAP92077.1 - 1.3e-07 30.3 1.1 2.3e-07 29.5 1.1 1.3 1 0 0 1 1 1 1 SBE2, cell-wall formation eIF2A PF08662.11 GAP92078.1 - 8.7e-27 94.3 0.4 4.5e-14 52.8 0.0 3.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 GAP92078.1 - 0.0028 17.5 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MciZ PF13072.6 GAP92078.1 - 0.62 9.9 2.3 0.58 10.0 0.2 2.1 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ Cpn60_TCP1 PF00118.24 GAP92079.1 - 4.5e-131 437.9 10.7 5.1e-131 437.7 10.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 GAP92079.1 - 0.084 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat FlgM PF04316.13 GAP92079.1 - 0.088 13.2 1.1 2.1 8.7 0.0 2.9 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF5442 PF17514.2 GAP92079.1 - 0.17 12.1 0.1 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5442) p450 PF00067.22 GAP92080.1 - 7.9e-43 146.9 0.0 1.1e-42 146.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 GAP92082.1 - 7.3e-20 71.2 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain HTH_IclR PF09339.10 GAP92082.1 - 0.00043 20.0 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain Dimerisation2 PF16864.5 GAP92082.1 - 0.0041 17.1 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 Dimerisation domain HTH_Tnp_ISL3 PF13542.6 GAP92082.1 - 0.039 13.4 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 CheR PF01739.18 GAP92082.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain HTH_AsnC-type PF13404.6 GAP92082.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain TFIIE_alpha PF02002.17 GAP92082.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_24 PF13412.6 GAP92082.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 GAP92082.1 - 0.15 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 MarR family Methyltransf_2 PF00891.18 GAP92083.1 - 1.9e-17 63.3 0.0 3.2e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 GAP92083.1 - 0.023 14.5 0.0 15 5.3 0.0 3.4 4 0 0 4 4 4 0 Methyltransferase domain Methyltransf_25 PF13649.6 GAP92083.1 - 0.12 13.1 0.0 0.31 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Dimerisation2 PF16864.5 GAP92083.1 - 0.19 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain MoaE PF02391.17 GAP92084.1 - 8.6e-40 135.6 0.0 1e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Lipase_GDSL_lke PF16255.5 GAP92084.1 - 0.024 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase OPT PF03169.15 GAP92085.1 - 8.2e-174 579.7 47.6 9.6e-174 579.4 47.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MmgE_PrpD PF03972.14 GAP92086.1 - 6.7e-144 479.7 0.0 8.9e-144 479.3 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family NUDE_C PF04880.13 GAP92086.1 - 0.93 10.0 6.5 1.9 8.9 6.5 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region SH3_1 PF00018.28 GAP92087.1 - 5e-14 51.6 0.2 7.9e-14 51.0 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAP92087.1 - 7.4e-12 44.9 0.1 1.1e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 GAP92087.1 - 1e-09 37.9 0.0 1.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PBP1_TM PF14812.6 GAP92088.1 - 6.3 7.2 28.3 2.4 8.6 3.5 4.3 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.8 GAP92088.1 - 8 7.5 24.6 6.4 7.8 2.1 4.3 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal Exo_endo_phos PF03372.23 GAP92089.1 - 1.9e-06 27.6 0.1 3.2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 GAP92090.1 - 2.2e-26 92.8 0.0 2.8e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92090.1 - 6.1e-14 51.9 0.0 8.4e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 GAP92090.1 - 4.4e-09 35.6 0.0 6e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 GAP92090.1 - 0.00017 21.6 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family TPPK_C PF12555.8 GAP92091.1 - 2.2 8.4 5.4 4.8 7.3 5.4 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal HET PF06985.11 GAP92092.1 - 3e-21 76.3 0.0 5.1e-17 62.6 0.0 2.6 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Mpv17_PMP22 PF04117.12 GAP92095.1 - 3.6e-14 52.7 1.0 3.6e-14 52.7 1.0 2.4 3 0 0 3 3 3 1 Mpv17 / PMP22 family YIF1 PF03878.15 GAP92096.1 - 4.6e-93 311.1 0.8 5.4e-93 310.9 0.8 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 GAP92096.1 - 0.0016 18.2 4.9 0.0016 18.2 4.9 1.7 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.13 GAP92097.1 - 1.7e-76 257.9 0.0 2.3e-76 257.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 GAP92097.1 - 1.5e-48 165.1 0.2 1.8e-46 158.3 0.2 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 GAP92097.1 - 3.4e-08 33.6 0.2 8.8e-08 32.3 0.2 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 GAP92097.1 - 7.1e-07 28.5 0.1 1.3e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 GAP92097.1 - 0.00033 20.4 0.0 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 GAP92097.1 - 0.0004 20.8 0.7 0.0022 18.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 GAP92097.1 - 0.0068 16.1 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 GAP92097.1 - 0.013 16.0 0.2 0.091 13.3 0.0 2.3 3 0 0 3 3 3 0 ABC transporter MMR_HSR1 PF01926.23 GAP92097.1 - 0.021 14.9 0.2 0.088 12.9 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.23 GAP92097.1 - 0.025 14.6 0.1 1.9 8.6 0.1 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 GAP92097.1 - 0.047 13.6 0.1 1.3 8.9 0.1 2.4 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAP92097.1 - 0.088 13.2 0.0 0.37 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 GAP92097.1 - 0.15 12.2 0.0 0.45 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain Peptidase_A4 PF01828.17 GAP92098.1 - 9.7e-25 87.3 1.0 1.3e-24 86.9 1.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family IBR PF01485.21 GAP92099.1 - 5.9e-12 45.6 28.5 3.9e-06 27.0 4.9 4.0 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 GAP92099.1 - 0.0011 18.9 6.3 0.0011 18.9 6.3 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 GAP92099.1 - 0.002 18.4 6.4 0.002 18.4 6.4 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 GAP92099.1 - 0.0034 17.3 7.0 0.0034 17.3 7.0 3.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAP92099.1 - 0.013 15.4 7.3 0.013 15.4 7.3 3.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAP92099.1 - 0.027 14.2 1.3 0.087 12.6 1.3 2.0 1 0 0 1 1 1 0 RING-like zinc finger Ribosomal_L14e PF01929.17 GAP92100.1 - 9.6e-26 90.1 3.1 1.4e-25 89.5 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 GAP92100.1 - 6.8e-06 25.8 0.1 1.2e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 KOW motif NAC PF01849.18 GAP92101.1 - 4.2e-23 81.1 0.2 1.3e-22 79.5 0.1 1.8 2 0 0 2 2 2 1 NAC domain CENP-B_dimeris PF09026.10 GAP92101.1 - 0.79 10.2 17.0 9.8 6.6 11.4 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Myc_N PF01056.18 GAP92101.1 - 1.8 8.3 11.7 3.5 7.4 11.7 1.5 1 1 0 1 1 1 0 Myc amino-terminal region Mt_ATP-synt_D PF05873.12 GAP92102.1 - 3.6e-20 72.4 2.9 4.6e-20 72.0 2.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) APG6_N PF17675.1 GAP92102.1 - 0.76 10.3 5.4 1.7 9.2 5.4 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region F-box-like PF12937.7 GAP92103.1 - 0.045 13.7 0.2 0.68 9.9 0.0 2.6 2 0 0 2 2 2 0 F-box-like Luteo_PO PF04662.13 GAP92103.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Luteovirus P0 protein EAF PF09816.9 GAP92104.1 - 1.4e-20 73.5 1.1 2.1e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor YlzJ PF14035.6 GAP92104.1 - 0.34 11.1 1.3 55 4.1 0.0 2.7 2 0 0 2 2 2 0 YlzJ-like protein DUF4551 PF15087.6 GAP92104.1 - 1.1 8.0 7.0 1.7 7.4 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DNA_pol_phi PF04931.13 GAP92104.1 - 9 4.3 30.2 16 3.5 30.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi zf-C2H2 PF00096.26 GAP92106.1 - 3.1e-07 30.5 21.0 0.013 15.9 2.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP92106.1 - 3.4e-05 24.3 17.7 0.14 13.0 2.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 GAP92106.1 - 0.035 14.7 9.1 0.41 11.3 0.5 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain PTP_tm PF18861.1 GAP92106.1 - 0.044 13.8 0.2 0.081 12.9 0.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J TraL PF07178.11 GAP92106.1 - 0.2 12.1 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 TraL protein SKG6 PF08693.10 GAP92106.1 - 0.24 10.8 1.0 0.49 9.8 1.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rick_17kDa_Anti PF05433.15 GAP92106.1 - 0.47 10.3 4.0 0.88 9.5 4.0 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain zf-C2H2_6 PF13912.6 GAP92106.1 - 0.8 9.8 10.2 1.6 8.8 1.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4690 PF15756.5 GAP92106.1 - 1.4 9.6 7.6 0.077 13.6 1.0 2.3 2 0 0 2 2 2 0 Small Novel Rich in Cartilage zf-Di19 PF05605.12 GAP92106.1 - 2.7 8.3 10.1 0.49 10.7 1.2 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FAD_binding_7 PF03441.14 GAP92107.1 - 2.7e-45 154.3 0.1 4.4e-45 153.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 GAP92107.1 - 6e-19 68.6 0.0 1.1e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase 4HBT PF03061.22 GAP92108.1 - 1.4e-05 25.3 0.1 4.6e-05 23.7 0.1 1.9 1 0 0 1 1 1 1 Thioesterase superfamily Polysacc_deac_1 PF01522.21 GAP92109.1 - 2.1e-19 69.6 0.0 4.5e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 GAP92109.1 - 1.8e-06 27.8 0.2 4e-06 26.6 0.2 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) NUDIX PF00293.28 GAP92109.1 - 0.086 12.9 0.2 0.74 9.9 0.0 2.2 2 0 0 2 2 2 0 NUDIX domain DUF2194 PF09960.9 GAP92109.1 - 0.11 10.8 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) adh_short_C2 PF13561.6 GAP92110.1 - 1.6e-64 217.7 1.1 1.9e-64 217.4 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP92110.1 - 1.5e-42 145.3 0.0 1.8e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP92110.1 - 2.9e-09 37.1 0.2 5.1e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 KR domain ThiF PF00899.21 GAP92110.1 - 0.14 11.5 0.2 0.87 8.9 0.1 2.1 1 1 1 2 2 2 0 ThiF family SQS_PSY PF00494.19 GAP92111.1 - 2.1e-63 214.3 0.2 3.1e-63 213.7 0.2 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF1656 PF07869.12 GAP92111.1 - 0.019 15.0 6.4 1.7 8.7 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1656) Amino_oxidase PF01593.24 GAP92112.1 - 8.6e-20 71.4 0.1 1.1e-19 71.0 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAP92112.1 - 6.5e-14 51.9 0.2 1.6e-13 50.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP92112.1 - 2.4e-09 37.2 3.8 2.4e-08 34.0 3.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP92112.1 - 3.1e-07 29.9 0.1 1.5e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP92112.1 - 6.9e-05 21.7 0.3 0.00037 19.3 1.8 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 GAP92112.1 - 0.00011 21.4 2.9 0.00018 20.7 2.9 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAP92112.1 - 0.00046 19.7 3.0 0.00071 19.0 3.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAP92112.1 - 0.0014 18.0 1.5 0.0019 17.5 1.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP92112.1 - 0.0077 15.5 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 GAP92112.1 - 0.023 14.0 0.3 0.034 13.4 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 GAP92112.1 - 0.072 13.7 0.8 0.17 12.5 0.8 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAP92112.1 - 0.092 11.8 1.0 0.21 10.6 1.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 GAP92112.1 - 0.14 11.8 0.6 0.24 11.0 0.6 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 GAP92112.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 GAP92112.1 - 0.22 11.5 2.0 0.35 10.9 0.4 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 GAP92112.1 - 0.36 9.9 5.7 0.065 12.3 2.3 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Beta-lactamase PF00144.24 GAP92113.1 - 1.3e-22 80.5 2.5 1.3e-22 80.5 2.5 2.7 1 1 2 3 3 3 1 Beta-lactamase Pkinase PF00069.25 GAP92114.1 - 8.9e-41 140.0 0.0 1.2e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92114.1 - 2.2e-23 82.9 0.0 3.9e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP92114.1 - 0.00037 19.9 0.0 0.00069 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 GAP92114.1 - 0.0019 17.6 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 GAP92114.1 - 0.0027 16.7 0.0 0.006 15.6 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain BAG PF02179.16 GAP92114.1 - 0.045 14.2 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 BAG domain APG9 PF04109.16 GAP92114.1 - 0.084 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg9 Pkinase PF00069.25 GAP92115.1 - 0.0026 17.2 0.0 0.0065 15.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92115.1 - 0.003 16.9 0.0 0.11 11.8 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase IL11 PF07400.11 GAP92115.1 - 0.043 13.5 0.1 0.079 12.6 0.1 1.4 1 0 0 1 1 1 0 Interleukin 11 Pilin_N PF07790.11 GAP92116.1 - 0.049 14.6 0.0 0.13 13.2 0.0 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal SPX PF03105.19 GAP92116.1 - 0.11 12.4 0.8 0.13 12.2 0.8 1.1 1 0 0 1 1 1 0 SPX domain Menin PF05053.13 GAP92116.1 - 0.19 10.1 0.7 0.27 9.6 0.7 1.3 1 0 0 1 1 1 0 Menin MAPEG PF01124.18 GAP92117.1 - 5.7e-18 65.1 2.1 7.8e-18 64.6 2.1 1.2 1 0 0 1 1 1 1 MAPEG family BNR PF02012.20 GAP92118.1 - 1 9.7 4.2 1.2 9.5 0.3 3.2 3 0 0 3 3 3 0 BNR/Asp-box repeat Glyco_hydro_67M PF07488.12 GAP92120.1 - 4.3e-140 466.4 0.0 6e-140 465.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 GAP92120.1 - 6.3e-89 297.3 2.1 9.5e-89 296.7 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 GAP92120.1 - 5.7e-30 104.1 0.0 8.9e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 GAP92120.1 - 0.0032 18.3 0.1 0.0087 16.8 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF4838 PF16126.5 GAP92120.1 - 0.043 13.2 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) DUF155 PF02582.14 GAP92122.1 - 1.1e-38 133.1 0.0 1.5e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Taxilin PF09728.9 GAP92122.1 - 0.079 12.1 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Prefoldin_3 PF13758.6 GAP92122.1 - 0.12 12.5 0.6 0.43 10.7 0.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit Cupin_1 PF00190.22 GAP92122.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 GAP92122.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) BNR_2 PF13088.6 GAP92123.1 - 9.4e-06 25.1 0.0 0.34 10.2 0.0 3.7 1 1 2 4 4 4 2 BNR repeat-like domain BNR PF02012.20 GAP92123.1 - 3.9e-05 23.0 11.9 3.5 8.0 0.2 5.6 5 0 0 5 5 5 2 BNR/Asp-box repeat Velvet PF11754.8 GAP92123.1 - 0.00081 19.4 1.7 0.00081 19.4 1.7 2.0 2 0 0 2 2 2 1 Velvet factor TFIIA PF03153.13 GAP92123.1 - 0.0013 18.8 15.1 0.0022 18.0 15.1 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 GAP92123.1 - 0.0015 18.2 19.4 0.01 15.4 4.1 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein IMUP PF15761.5 GAP92123.1 - 0.007 17.0 17.2 0.12 13.1 2.5 2.7 2 0 0 2 2 2 2 Immortalisation up-regulated protein FAM70 PF14967.6 GAP92123.1 - 0.062 12.8 4.4 0.11 11.9 4.4 1.3 1 0 0 1 1 1 0 FAM70 protein GREB1 PF15782.5 GAP92123.1 - 0.17 9.0 2.7 0.25 8.4 2.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 GAP92123.1 - 0.21 10.2 4.0 0.29 9.8 4.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3446 PF11928.8 GAP92123.1 - 0.38 11.1 25.6 0.15 12.4 3.6 2.8 2 1 0 2 2 2 0 Early growth response N-terminal domain Suf PF05843.14 GAP92123.1 - 0.4 10.6 8.2 0.6 10.1 8.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Apt1 PF10351.9 GAP92123.1 - 0.52 9.1 3.1 0.65 8.8 0.3 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain Tim54 PF11711.8 GAP92123.1 - 0.76 8.5 6.8 1.1 7.9 6.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TCP PF03634.13 GAP92123.1 - 1.2 9.7 10.5 1.8 9.1 6.8 2.2 2 0 0 2 2 2 0 TCP family transcription factor SARAF PF06682.12 GAP92123.1 - 1.6 8.3 10.3 0.24 11.0 5.0 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CCSAP PF15748.5 GAP92123.1 - 3.7 7.7 20.3 1.3 9.2 13.5 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 GAP92123.1 - 5.9 5.6 7.5 10 4.8 7.5 1.3 1 0 0 1 1 1 0 Presenilin DUF1180 PF06679.12 GAP92123.1 - 6.6 7.1 8.1 1.1 9.6 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Asp PF00026.23 GAP92124.1 - 6.6e-109 364.1 0.1 7.8e-109 363.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP92124.1 - 6.2e-15 55.9 1.9 3.4e-13 50.2 1.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 GAP92124.1 - 3.1e-06 27.8 0.3 0.078 13.6 0.1 3.5 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 GAP92124.1 - 0.00055 19.7 0.0 0.0071 16.1 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 GAP92124.1 - 0.003 18.1 0.0 3.1 8.4 0.0 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease DUF3144 PF11342.8 GAP92125.1 - 0.13 12.5 0.4 0.39 11.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) SPT2 PF08243.11 GAP92125.1 - 0.45 11.1 3.1 1.5 9.4 3.1 1.9 1 0 0 1 1 1 0 SPT2 chromatin protein SHMT PF00464.19 GAP92126.1 - 7.1e-207 686.7 0.0 8.3e-207 686.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 GAP92126.1 - 0.024 13.9 0.0 0.16 11.2 0.0 2.0 1 1 1 2 2 2 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 GAP92126.1 - 0.043 12.3 0.0 0.07 11.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme adh_short PF00106.25 GAP92127.1 - 9.2e-13 48.1 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP92127.1 - 0.00032 20.6 0.1 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 GAP92127.1 - 0.0034 17.0 0.0 0.0099 15.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 GAP92127.1 - 0.011 15.3 0.1 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Gln-synt_C PF00120.24 GAP92128.1 - 2.1e-33 115.8 0.0 8.7e-33 113.7 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain UDPGT PF00201.18 GAP92129.1 - 4.2e-07 29.1 0.1 6.2e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 GAP92129.1 - 0.23 11.5 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Aminotran_1_2 PF00155.21 GAP92130.1 - 9.5e-39 133.6 0.0 1.3e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAP92130.1 - 1.3e-07 30.9 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 GAP92130.1 - 9.1e-07 27.7 0.0 1.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 GAP92130.1 - 8.8e-06 24.8 0.0 1.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 GAP92130.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 GAP92130.1 - 0.00025 20.5 0.3 0.00032 20.1 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 GAP92130.1 - 0.0052 15.7 0.0 0.0084 15.0 0.0 1.3 1 0 0 1 1 1 1 Allinase FMN_red PF03358.15 GAP92131.1 - 3.7e-07 30.0 0.0 5.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 GAP92131.1 - 1.7e-05 24.6 0.0 2.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 GAP92131.1 - 0.0013 19.0 0.1 0.043 14.0 0.1 2.4 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 GAP92131.1 - 0.047 13.9 0.0 0.25 11.6 0.0 1.9 1 1 1 2 2 2 0 Flavodoxin domain CR6_interact PF10147.9 GAP92132.1 - 0.01 15.6 0.4 0.014 15.1 0.4 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Saf_2TM PF18303.1 GAP92132.1 - 0.054 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain RCR PF12273.8 GAP92132.1 - 0.23 12.1 3.6 16 6.2 0.9 2.9 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red CoxIIa PF08113.11 GAP92132.1 - 0.59 10.0 4.2 1.1 9.1 4.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family AAA PF00004.29 GAP92133.1 - 2.3e-18 66.9 0.0 4.5e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 GAP92133.1 - 0.00074 18.9 1.8 0.0018 17.6 0.8 1.9 1 1 0 2 2 2 1 KaiC AAA_16 PF13191.6 GAP92133.1 - 0.0013 19.2 0.0 0.0037 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 GAP92133.1 - 0.0054 16.7 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zot PF05707.12 GAP92133.1 - 0.04 13.5 0.1 0.58 9.8 0.0 2.4 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_22 PF13401.6 GAP92133.1 - 0.045 14.0 0.2 0.23 11.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.12 GAP92133.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin HET PF06985.11 GAP92134.1 - 2.3e-20 73.4 0.3 4.7e-20 72.4 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Olduvai PF06758.13 GAP92134.1 - 0.34 11.2 1.8 35 4.7 0.0 3.9 3 1 1 4 4 4 0 Olduvai domain Ribosomal_S8 PF00410.19 GAP92136.1 - 5.4e-09 36.1 0.0 2.1e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.20 GAP92138.1 - 7e-94 314.8 0.0 1.4e-93 313.8 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GTP_EFTU PF00009.27 GAP92139.1 - 2.7e-59 200.0 0.3 6e-59 198.8 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 GAP92139.1 - 1.7e-33 115.0 0.0 3.4e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 GAP92139.1 - 6.2e-32 109.5 0.0 1.3e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 GAP92139.1 - 4.5e-23 81.1 0.0 1.1e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 GAP92139.1 - 1.3e-13 51.2 0.0 3.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 GAP92139.1 - 8.7e-07 28.8 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 GAP92139.1 - 0.019 15.1 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Asp PF00026.23 GAP92140.1 - 6.4e-64 216.3 1.1 8.3e-64 216.0 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 GAP92140.1 - 4.8e-08 33.4 2.9 3e-07 30.8 0.6 3.0 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 GAP92140.1 - 0.0063 17.0 0.1 18 5.9 0.0 3.6 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 GAP92140.1 - 0.024 15.3 0.0 21 5.8 0.1 3.1 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 GAP92140.1 - 0.092 12.5 0.0 0.83 9.4 0.0 2.3 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Peptidase_M14 PF00246.24 GAP92141.1 - 3.4e-72 243.7 0.0 4.4e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 GAP92141.1 - 0.029 14.7 0.1 0.097 13.1 0.0 1.9 2 0 0 2 2 2 0 Carboxypeptidase activation peptide RFX1_trans_act PF04589.13 GAP92141.1 - 0.22 11.7 0.2 0.22 11.7 0.2 1.7 2 0 0 2 2 2 0 RFX1 transcription activation region G_glu_transpept PF01019.21 GAP92142.1 - 2.6e-167 557.7 0.1 3.2e-167 557.4 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase NAD_binding_10 PF13460.6 GAP92142.1 - 1.3e-17 64.3 0.0 3.1e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans PF04082.18 GAP92143.1 - 3.2e-19 69.0 0.0 6e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 GAP92144.1 - 4.6e-162 539.7 0.0 5.2e-162 539.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Kelch_5 PF13854.6 GAP92145.1 - 1e-10 41.3 1.8 2e-10 40.4 0.2 2.5 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 GAP92145.1 - 6e-07 29.2 8.0 0.57 10.3 0.4 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 GAP92145.1 - 0.0053 17.0 8.7 1 9.7 0.4 4.6 3 1 1 4 4 4 1 Kelch motif EphA2_TM PF14575.6 GAP92145.1 - 0.0086 16.9 0.1 0.031 15.1 0.0 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Kelch_1 PF01344.25 GAP92145.1 - 0.012 15.1 10.9 0.97 9.1 0.2 4.6 4 1 0 4 4 4 0 Kelch motif Protocadherin PF08374.11 GAP92145.1 - 0.061 13.3 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Kelch_3 PF13415.6 GAP92145.1 - 0.23 11.8 8.2 1.9 8.9 0.0 4.2 4 1 0 4 4 4 0 Galactose oxidase, central domain DUF3309 PF11752.8 GAP92145.1 - 0.23 11.5 7.1 0.62 10.1 7.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Nitr_red_bet_C PF14711.6 GAP92146.1 - 4.1e-06 26.4 0.0 5.9 6.7 0.0 5.0 3 1 2 5 5 5 2 Respiratory nitrate reductase beta C-terminal DUF433 PF04255.14 GAP92146.1 - 1.3e-05 25.0 0.3 28 4.6 0.0 5.4 5 0 0 5 5 5 0 Protein of unknown function (DUF433) DUF2420 PF10336.9 GAP92146.1 - 0.00046 20.2 0.0 7.6 6.6 0.0 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF2420) DUF2167 PF09935.9 GAP92146.1 - 0.0041 16.3 3.3 6.3 5.9 0.1 3.4 1 1 2 4 4 4 3 Protein of unknown function (DUF2167) Cna_B PF05738.13 GAP92146.1 - 0.025 15.1 2.2 61 4.2 0.1 4.4 1 1 4 5 5 5 0 Cna protein B-type domain TCL1_MTCP1 PF01840.17 GAP92146.1 - 0.028 14.1 0.5 26 4.5 0.0 3.6 3 1 1 4 4 4 0 TCL1/MTCP1 family Pullulanase_Ins PF18494.1 GAP92146.1 - 1.3 9.5 5.3 1.7e+02 2.8 0.1 4.0 4 0 0 4 4 4 0 Pullulanase Ins domain DUF3328 PF11807.8 GAP92147.1 - 1.5e-49 168.7 0.2 1.9e-49 168.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_61 PF03443.14 GAP92148.1 - 0.03 14.3 0.3 0.56 10.1 0.3 2.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 GFO_IDH_MocA PF01408.22 GAP92150.1 - 9e-22 78.1 0.1 1.4e-21 77.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAP92150.1 - 4.4e-11 42.8 0.0 1.2e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 GAP92150.1 - 0.0022 18.1 0.1 0.017 15.2 0.0 2.2 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 GAP92150.1 - 0.019 15.4 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 GAP92150.1 - 0.033 14.9 0.0 0.072 13.8 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain DUF4291 PF14124.6 GAP92151.1 - 1.1e-68 230.7 1.6 1.3e-68 230.5 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) CFEM PF05730.11 GAP92153.1 - 0.004 17.2 4.0 0.0095 16.0 4.0 1.6 1 1 0 1 1 1 1 CFEM domain SBP_bac_6 PF13343.6 GAP92155.1 - 1.2e-14 54.3 0.1 2.1e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 GAP92155.1 - 1.6e-10 41.3 0.1 3e-10 40.4 0.1 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 GAP92155.1 - 1.3e-08 34.9 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 GAP92155.1 - 0.0026 17.7 1.6 0.0097 15.9 1.6 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein F-box-like PF12937.7 GAP92156.1 - 1.6e-05 24.7 0.1 3.9e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF1857 PF08982.11 GAP92159.1 - 9e-56 187.8 0.1 1e-55 187.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Noc2 PF03715.13 GAP92160.1 - 1.4e-128 428.3 0.0 2.6e-128 427.5 0.0 1.4 1 0 0 1 1 1 1 Noc2p family VPS28 PF03997.12 GAP92161.1 - 4.5e-64 215.6 0.2 5.4e-64 215.4 0.2 1.1 1 0 0 1 1 1 1 VPS28 protein tRNA-synt_2c PF01411.19 GAP92162.1 - 3.7e-09 35.6 0.7 4.7e-09 35.3 0.2 1.3 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 GAP92162.1 - 5e-07 29.7 0.3 9.9e-07 28.8 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain ParD_antitoxin PF03693.14 GAP92162.1 - 0.15 12.4 0.2 0.78 10.2 0.1 2.2 2 1 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH DUF3419 PF11899.8 GAP92163.1 - 9.3e-166 551.8 0.0 1.2e-165 551.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 GAP92163.1 - 1.8e-14 53.9 0.0 1.6e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP92163.1 - 1e-07 32.6 0.0 4.3e-06 27.3 0.0 3.3 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP92163.1 - 2.8e-06 28.0 0.0 3e-05 24.7 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP92163.1 - 1e-05 26.1 0.0 0.00076 20.1 0.0 3.5 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP92163.1 - 0.00012 21.8 0.0 0.001 18.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP92163.1 - 0.00022 20.6 0.0 0.042 13.2 0.0 2.5 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family PCMT PF01135.19 GAP92163.1 - 0.00096 19.0 0.0 0.0024 17.7 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Glyco_hydro_28 PF00295.17 GAP92164.1 - 1.3e-37 129.6 7.0 1.9e-37 129.0 7.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 BTB PF00651.31 GAP92165.1 - 0.21 11.8 0.0 0.46 10.7 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Bacillus_PapR PF05968.11 GAP92166.1 - 1.3 9.0 3.7 4 7.4 2.7 2.2 2 0 0 2 2 2 0 Bacillus PapR protein RNase_P_p30 PF01876.16 GAP92167.1 - 1.4e-55 188.1 0.0 1.8e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 zinc_ribbon_15 PF17032.5 GAP92168.1 - 9.4e-06 26.3 1.0 1.4e-05 25.8 1.0 1.2 1 0 0 1 1 1 1 zinc-ribbon family PriA_CRR PF18319.1 GAP92168.1 - 0.25 11.4 7.4 0.26 11.3 0.1 2.6 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Peptidase_M50B PF13398.6 GAP92169.1 - 0.16 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like eIF_4EBP PF05456.11 GAP92170.1 - 0.043 13.8 0.9 0.043 13.8 0.9 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Neur_chan_memb PF02932.16 GAP92170.1 - 0.049 13.7 12.2 0.065 13.3 12.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.9 GAP92170.1 - 0.18 11.4 28.3 0.28 10.8 28.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF913 PF06025.12 GAP92170.1 - 0.19 10.7 7.1 0.25 10.3 7.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 GAP92170.1 - 0.21 10.3 14.5 0.25 10.1 14.5 1.1 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 GAP92170.1 - 0.54 10.0 10.1 0.72 9.6 10.1 1.2 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.7 GAP92170.1 - 1.2 7.2 14.6 1.4 6.9 14.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPAT_C PF15712.5 GAP92170.1 - 1.9 7.0 17.0 2.2 6.8 17.0 1.0 1 0 0 1 1 1 0 NPAT C terminus SAPS PF04499.15 GAP92170.1 - 2.6 6.7 10.2 2.9 6.6 10.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5427 PF10310.9 GAP92170.1 - 3.4 6.5 22.1 4.1 6.3 22.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 GAP92170.1 - 3.6 6.5 13.9 4.5 6.2 13.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Menin PF05053.13 GAP92170.1 - 5.2 5.3 12.2 6.3 5.0 12.2 1.1 1 0 0 1 1 1 0 Menin DUF4551 PF15087.6 GAP92170.1 - 5.8 5.6 10.8 6.9 5.4 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ALMT PF11744.8 GAP92170.1 - 5.8 5.6 10.0 7.2 5.3 10.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Pkinase PF00069.25 GAP92171.1 - 2.9e-60 203.9 0.0 4.1e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92171.1 - 7.7e-29 100.8 0.0 1.1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP92171.1 - 1.2e-07 31.3 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAP92171.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP92171.1 - 0.024 14.6 0.0 1.1 9.1 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family UQ_con PF00179.26 GAP92172.1 - 1.5e-49 167.3 0.0 1.9e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAP92172.1 - 5.6e-07 29.3 0.0 7.3e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAP92172.1 - 0.0019 18.5 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 GAP92172.1 - 0.0037 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 UEV domain Ribosomal_L31e PF01198.19 GAP92173.1 - 5.1e-41 138.8 1.5 8.1e-41 138.1 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 GAP92173.1 - 0.082 13.0 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein RGS PF00615.19 GAP92174.1 - 8.2e-13 48.7 0.0 1.7e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain PCI PF01399.27 GAP92175.1 - 5.5e-06 26.8 0.0 9.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 PCI domain E1-E2_ATPase PF00122.20 GAP92176.1 - 1.2e-50 171.6 0.7 1.2e-50 171.6 0.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 GAP92176.1 - 2.4e-43 146.4 0.8 3.1e-10 40.3 0.1 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 GAP92176.1 - 7.9e-42 143.9 2.8 1.5e-41 143.0 2.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 GAP92176.1 - 1.3e-06 28.4 1.5 8.4e-05 22.4 0.4 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 GAP92176.1 - 0.0042 17.1 4.7 0.0086 16.1 1.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1656) HAD PF12710.7 GAP92176.1 - 0.016 15.6 0.1 0.035 14.5 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAP92176.1 - 0.088 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Dehyd-heme_bind PF09098.10 GAP92177.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Amidase PF01425.21 GAP92178.1 - 1.3e-35 123.3 0.8 5.3e-35 121.3 0.3 1.9 2 0 0 2 2 2 1 Amidase PARM PF17061.5 GAP92179.1 - 4.1 7.5 15.7 6 6.9 15.7 1.2 1 0 0 1 1 1 0 PARM Pkinase PF00069.25 GAP92180.1 - 4.8e-14 52.3 0.0 7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92180.1 - 1.3e-07 31.2 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP92180.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 GAP92182.1 - 7.1e-38 130.4 39.4 2.6e-37 128.5 33.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP92182.1 - 1.9e-10 40.2 4.2 1.9e-10 40.2 4.2 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 GAP92182.1 - 5.3e-07 28.4 0.8 1e-06 27.5 0.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 GAP92182.1 - 0.0013 17.3 1.4 0.002 16.6 1.4 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector TNFR_16_TM PF18422.1 GAP92182.1 - 0.55 10.2 6.7 7.5 6.6 0.0 3.5 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF2263 PF10021.9 GAP92183.1 - 8.2e-20 71.7 0.0 1.4e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 GAP92183.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Macro domain Mg_chelatase PF01078.21 GAP92183.1 - 0.17 11.3 0.0 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI EPSP_synthase PF00275.20 GAP92184.1 - 2.2e-130 435.1 0.0 3.1e-130 434.6 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 GAP92184.1 - 9.2e-101 336.4 0.0 1.4e-100 335.8 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 GAP92184.1 - 8.3e-56 189.8 0.0 1.4e-55 189.0 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 GAP92184.1 - 2.1e-37 128.7 0.0 1.3e-35 122.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 GAP92184.1 - 2.8e-24 85.2 0.0 7.6e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 GAP92184.1 - 1.4e-06 28.2 0.1 1.2e-05 25.2 0.1 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 GAP92184.1 - 7.3e-06 25.6 1.0 2.1e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 GAP92184.1 - 0.094 12.8 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase zf-C2H2 PF00096.26 GAP92185.1 - 1.6e-08 34.5 13.4 0.014 15.9 1.7 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP92185.1 - 0.00038 21.0 12.7 1.1 10.3 1.5 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger CENP-T_C PF15511.6 GAP92186.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 GAP92186.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 GAP92186.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 GAP92186.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 GAP92186.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 GAP92186.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAP92186.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 GAP92186.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 GAP92186.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 GAP92187.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 GAP92187.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 GAP92187.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 GAP92187.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 GAP92187.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 GAP92187.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 GAP92187.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated RNA_pol_Rpb1_5 PF04998.17 GAP92188.1 - 1e-87 294.0 0.1 2.2e-87 292.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 GAP92188.1 - 2.2e-67 226.5 0.2 5.3e-67 225.2 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 GAP92188.1 - 2.3e-32 112.1 0.0 1.9e-31 109.1 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 GAP92188.1 - 5.1e-30 104.9 0.0 6.6e-29 101.2 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 GAP92188.1 - 4.1e-15 55.6 0.5 2.4e-14 53.2 0.1 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 DUF2990 PF11693.8 GAP92188.1 - 0.19 11.9 0.1 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) AAA_15 PF13175.6 GAP92188.1 - 0.88 9.2 10.4 1.9 8.1 2.2 2.3 2 0 0 2 2 2 0 AAA ATPase domain HET PF06985.11 GAP92189.1 - 3.7e-27 95.5 0.0 8e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PRP3 PF08572.10 GAP92190.1 - 1.7e-73 247.1 3.8 3.5e-73 246.0 3.8 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 GAP92190.1 - 7.9e-46 155.8 0.3 7.9e-46 155.8 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DEAD_2 PF06733.15 GAP92191.1 - 5.7e-57 192.2 0.3 1.2e-56 191.1 0.3 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 GAP92191.1 - 8.4e-49 165.8 8.0 1.9e-45 154.9 0.6 3.3 3 0 0 3 3 3 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 GAP92191.1 - 1.2e-43 149.3 0.0 5.8e-43 147.0 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 GAP92191.1 - 5.1e-05 23.3 0.0 0.0019 18.2 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 GAP92191.1 - 0.0022 17.8 0.0 0.53 10.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 GAP92191.1 - 0.0027 16.5 0.0 0.029 13.1 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.9 GAP92191.1 - 0.04 13.2 0.0 3.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 GAP92191.1 - 0.075 13.3 0.1 5.9 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Meis_PKNOX_N PF16493.5 GAP92191.1 - 0.18 12.2 0.7 1.2 9.5 0.0 2.6 3 0 0 3 3 3 0 N-terminal of Homeobox Meis and PKNOX1 Troponin PF00992.20 GAP92191.1 - 2.5 8.4 10.3 2.2 8.6 1.0 2.4 2 0 0 2 2 2 0 Troponin DNA_pol_phi PF04931.13 GAP92191.1 - 4.5 5.2 14.4 17 3.3 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase phi Helo_like_N PF17111.5 GAP92192.1 - 0.012 15.0 0.1 0.26 10.6 0.0 2.5 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Spore_III_AB PF09548.10 GAP92192.1 - 0.22 11.6 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DDHD PF02862.17 GAP92194.1 - 3.7e-24 86.1 0.3 1.4e-20 74.4 0.0 3.4 3 1 0 3 3 3 1 DDHD domain Abhydrolase_1 PF00561.20 GAP92194.1 - 0.00075 19.2 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1244 PF06844.11 GAP92194.1 - 0.07 13.3 0.8 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) DSPc PF00782.20 GAP92195.1 - 2.7e-26 92.0 0.0 1.4e-21 76.7 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 GAP92195.1 - 0.00083 19.0 0.0 0.0044 16.6 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 GAP92195.1 - 0.15 12.2 0.0 0.45 10.6 0.1 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate ANAPC4_WD40 PF12894.7 GAP92196.1 - 0.00016 21.9 0.0 0.33 11.3 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 GAP92196.1 - 0.0041 17.9 0.2 0.37 11.7 0.0 3.8 3 1 0 3 3 3 1 WD domain, G-beta repeat CNH PF00780.22 GAP92196.1 - 0.0051 16.5 0.0 3.2 7.3 0.0 3.3 3 1 0 3 3 3 2 CNH domain Coatomer_WDAD PF04053.14 GAP92196.1 - 0.024 13.7 0.0 0.78 8.7 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region Cupin_8 PF13621.6 GAP92197.1 - 8.5e-35 120.7 0.0 1.3e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 GAP92197.1 - 3e-20 72.9 0.0 4.9e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 GAP92197.1 - 7.2e-10 38.7 3.0 3.5e-05 23.7 0.0 4.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 GAP92197.1 - 2.3e-05 24.5 1.2 0.38 11.1 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 GAP92197.1 - 0.00037 20.4 0.0 1 9.4 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 GAP92197.1 - 0.00082 18.9 0.4 0.59 9.8 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Cupin_4 PF08007.12 GAP92197.1 - 0.0035 16.9 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_6 PF13964.6 GAP92197.1 - 0.01 16.1 0.9 4.6 7.7 0.0 3.8 4 0 0 4 4 4 0 Kelch motif MTS PF05175.14 GAP92197.1 - 0.18 11.4 0.0 0.65 9.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Transket_pyr PF02779.24 GAP92198.1 - 3.6e-65 219.0 0.0 6.2e-65 218.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 GAP92198.1 - 4.3e-57 192.1 0.1 7.4e-57 191.3 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 GAP92198.1 - 1e-55 188.8 0.0 1.5e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 GAP92198.1 - 1.8e-19 69.1 1.5 3.9e-19 68.0 1.5 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus baeRF_family12 PF18856.1 GAP92198.1 - 0.014 15.9 1.3 0.12 13.0 0.0 2.8 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 PFOR_II PF17147.4 GAP92198.1 - 0.054 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II PH_TFIIH PF08567.11 GAP92199.1 - 3.7e-25 88.1 0.0 1e-24 86.7 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 GAP92199.1 - 6.2e-23 80.6 4.9 3.2e-11 43.1 0.4 3.2 3 0 0 3 3 3 2 BSD domain PBP1_TM PF14812.6 GAP92200.1 - 0.01 16.2 3.9 0.022 15.1 3.9 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 GAP92200.1 - 0.012 15.4 3.6 0.012 15.4 3.6 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3439 PF11921.8 GAP92200.1 - 0.068 13.1 0.8 0.15 12.0 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CENP-B_dimeris PF09026.10 GAP92200.1 - 0.11 12.9 9.3 0.23 11.9 9.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 GAP92200.1 - 0.12 11.7 5.3 0.16 11.3 5.3 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 GAP92200.1 - 1.4 7.0 4.3 2 6.4 4.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 GAP92200.1 - 2.5 8.1 6.3 0.58 10.2 3.0 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.11 GAP92200.1 - 8.6 4.3 10.2 0.14 10.2 2.3 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen WD40 PF00400.32 GAP92202.1 - 1.1e-23 83.0 19.4 2.6e-08 34.4 0.3 6.8 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP92202.1 - 1.6e-07 31.5 1.2 0.47 10.8 0.1 5.2 4 3 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP92202.1 - 0.017 14.1 0.4 0.32 9.9 0.3 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WDCP PF15390.6 GAP92202.1 - 0.29 9.5 0.9 1.9 6.8 0.2 2.0 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family DAO PF01266.24 GAP92203.1 - 1.6e-53 182.6 0.0 2.1e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 GAP92203.1 - 9.3e-44 148.3 0.0 1.6e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 GAP92203.1 - 1.9e-06 27.2 0.2 5.2e-06 25.8 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAP92203.1 - 3.8e-05 23.2 4.7 0.0011 18.4 4.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAP92203.1 - 3.9e-05 23.1 0.0 6.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP92203.1 - 0.00029 20.2 0.0 0.00061 19.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAP92203.1 - 0.003 16.9 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAP92203.1 - 0.032 14.5 0.1 0.13 12.5 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 GAP92203.1 - 0.032 13.3 0.1 0.086 11.9 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 GAP92203.1 - 0.044 13.7 0.3 0.083 12.8 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 GAP92203.1 - 0.047 12.4 0.3 0.074 11.7 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Methyltransf_34 PF11312.8 GAP92203.1 - 0.049 12.9 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Pyr_redox PF00070.27 GAP92203.1 - 0.065 13.8 0.5 0.23 12.0 0.5 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 GAP92203.1 - 0.2 10.8 0.1 0.4 9.8 0.0 1.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) RGS PF00615.19 GAP92204.1 - 1.2e-07 32.1 0.0 1.8e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3337 PF11816.8 GAP92207.1 - 5e-57 192.5 0.0 1e-56 191.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 GAP92207.1 - 2.7e-21 75.5 12.1 3.1e-05 24.7 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 GAP92207.1 - 0.00018 20.3 0.8 0.0026 16.5 0.2 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 GAP92207.1 - 0.049 13.9 0.1 2.9 8.3 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP92207.1 - 0.14 11.1 0.0 0.88 8.5 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mito_carr PF00153.27 GAP92208.1 - 1.8e-45 152.8 6.8 3.3e-18 65.4 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 GAP92208.1 - 9.9e-05 21.6 1.0 0.018 14.2 0.1 2.4 2 0 0 2 2 2 2 Gammaproteobacterial serine protease ATP_bind_3 PF01171.20 GAP92209.1 - 1.4e-40 139.0 0.0 1.6e-39 135.6 0.0 2.1 1 1 0 1 1 1 1 PP-loop family Troponin PF00992.20 GAP92210.1 - 0.0036 17.6 2.1 0.0068 16.7 2.1 1.3 1 0 0 1 1 1 1 Troponin Arb2 PF09757.9 GAP92211.1 - 6.3e-97 323.7 0.0 8.6e-97 323.3 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 GAP92211.1 - 1.6e-81 274.2 0.0 2.2e-81 273.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain F-box-like PF12937.7 GAP92212.1 - 0.04 13.8 0.0 0.62 10.0 0.0 2.5 2 0 0 2 2 2 0 F-box-like Brix PF04427.18 GAP92213.1 - 3.1e-36 125.3 0.0 4.5e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain Str_synth PF03088.16 GAP92213.1 - 0.023 14.8 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Strictosidine synthase p450 PF00067.22 GAP92215.1 - 2.5e-44 151.8 0.0 2e-25 89.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 GAP92216.1 - 4.3e-27 95.0 48.1 7.3e-17 61.3 27.7 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 GAP92216.1 - 8.1e-08 31.1 10.3 1.1e-06 27.3 10.3 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP92216.1 - 1.3e-07 30.9 27.0 1.8e-06 27.1 9.6 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter SLATT_3 PF18184.1 GAP92216.1 - 0.057 13.6 0.0 0.23 11.6 0.0 2.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 4HBT_3 PF13622.6 GAP92217.1 - 2.7e-43 149.0 2.3 5.8e-43 147.9 2.3 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 GAP92217.1 - 1.1e-11 44.7 0.0 2.9e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA thioesterase ADH_zinc_N PF00107.26 GAP92217.1 - 3.7e-07 30.2 0.0 7.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3671 PF12420.8 GAP92218.1 - 7 6.8 6.0 18 5.4 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function AMP-binding PF00501.28 GAP92219.1 - 3.5e-74 249.9 0.0 7.3e-74 248.9 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 GAP92219.1 - 3e-67 226.8 0.0 5.4e-67 226.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 GAP92219.1 - 1.7e-61 208.3 0.0 2.7e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 GAP92219.1 - 2.3e-54 184.0 0.9 2.3e-52 177.5 0.0 3.2 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 GAP92219.1 - 5.4e-42 144.4 0.0 1.2e-41 143.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAP92219.1 - 1.2e-37 129.8 0.0 2.1e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAP92219.1 - 1.2e-31 109.1 0.0 3.5e-31 107.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 GAP92219.1 - 1.7e-29 102.8 0.0 2.9e-28 98.7 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 GAP92219.1 - 1.3e-16 60.7 1.4 8.5e-08 32.4 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 GAP92219.1 - 4.4e-16 59.4 0.0 1.4e-15 57.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP92219.1 - 2.1e-13 50.4 0.0 5.7e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAP92219.1 - 1.2e-12 48.3 0.0 3.1e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 GAP92219.1 - 4.4e-11 43.3 0.1 2.6e-10 40.9 0.0 2.5 3 0 0 3 3 1 1 Methyltransferase domain adh_short PF00106.25 GAP92219.1 - 6.9e-11 42.0 0.0 3.9e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 GAP92219.1 - 2.4e-10 40.9 0.0 1.1e-09 38.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 GAP92219.1 - 5e-07 29.4 0.0 3.3e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 GAP92219.1 - 3.5e-06 26.9 0.0 2.2e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP92219.1 - 6.5e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 GAP92219.1 - 1.7e-05 24.3 0.0 3.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C PF13193.6 GAP92219.1 - 2.5e-05 25.2 0.0 7.1e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 GAP92219.1 - 0.0001 21.4 0.0 0.0012 17.9 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.9 GAP92219.1 - 0.0037 17.0 0.0 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase SAT PF16073.5 GAP92219.1 - 0.034 13.9 0.9 0.51 10.0 0.3 2.6 2 1 0 2 2 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 GAP92219.1 - 0.075 12.9 0.2 0.22 11.4 0.2 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RmlD_sub_bind PF04321.17 GAP92219.1 - 0.085 11.9 0.0 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain LRR_4 PF12799.7 GAP92221.1 - 2e-29 101.1 45.5 2.1e-05 24.8 0.2 9.5 7 4 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 GAP92221.1 - 1.9e-21 75.6 45.5 0.0001 22.0 0.5 8.7 3 2 7 10 10 10 10 Leucine rich repeat LRR_9 PF14580.6 GAP92221.1 - 0.072 12.6 15.5 0.21 11.1 0.4 4.6 2 2 2 5 5 5 0 Leucine-rich repeat Meleagrin PF08189.11 GAP92222.1 - 0.0077 15.9 2.5 0.016 14.9 2.5 1.5 1 0 0 1 1 1 1 Meleagrin/Cygnin family CENP-B_dimeris PF09026.10 GAP92222.1 - 2.6 8.5 8.5 3.9 7.9 7.8 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3552 PF12072.8 GAP92223.1 - 0.075 12.4 14.3 0.13 11.7 14.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 GAP92223.1 - 0.85 8.9 5.9 1.5 8.1 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPAM PF02090.15 GAP92223.1 - 2 8.2 9.7 4.2 7.2 8.3 2.0 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein FUSC PF04632.12 GAP92223.1 - 7.2 5.0 6.1 11 4.4 6.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Thiolase_N PF00108.23 GAP92224.1 - 1.9e-66 224.1 4.2 2.7e-66 223.6 4.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 GAP92224.1 - 2.3e-40 137.1 1.7 3e-40 136.7 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain Dynamin_N PF00350.23 GAP92225.1 - 1.9e-36 125.6 0.0 3.5e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 GAP92225.1 - 2.5e-26 92.5 0.1 4.3e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 GAP92225.1 - 5.6e-05 23.2 0.1 0.0003 20.8 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Mer2 PF09074.10 GAP92225.1 - 0.013 15.3 0.3 0.036 13.9 0.1 1.8 2 0 0 2 2 2 0 Mer2 DUF2267 PF10025.9 GAP92225.1 - 0.015 15.6 1.0 0.94 9.8 0.0 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) Med9 PF07544.13 GAP92225.1 - 0.048 13.8 0.4 0.16 12.1 0.4 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AAA_15 PF13175.6 GAP92225.1 - 0.065 12.9 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Fungal_trans PF04082.18 GAP92226.1 - 8.8e-20 70.8 0.0 1.5e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_33 PF13671.6 GAP92227.1 - 1.4e-05 25.3 0.0 2.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 GAP92227.1 - 3.7e-05 23.6 0.0 0.0099 15.6 0.0 2.1 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 GAP92227.1 - 0.00058 19.8 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 GAP92227.1 - 0.007 16.9 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 GAP92227.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 GAP92227.1 - 0.027 13.9 0.0 0.069 12.6 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 GAP92227.1 - 0.036 14.5 0.9 0.14 12.6 0.9 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 GAP92227.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 GAP92227.1 - 0.049 12.8 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 GAP92227.1 - 0.05 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase MeaB PF03308.16 GAP92227.1 - 0.15 11.1 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Iso_dh PF00180.20 GAP92228.1 - 1.4e-87 294.1 0.0 1.6e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Zn_clus PF00172.18 GAP92229.1 - 5.5e-08 32.8 10.4 8.2e-08 32.3 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FTO_CTD PF12934.7 GAP92229.1 - 0.047 13.5 0.5 0.088 12.6 0.3 1.6 2 0 0 2 2 2 0 FTO C-terminal domain Chlam_OMP3 PF03503.13 GAP92229.1 - 0.084 13.2 5.1 0.17 12.2 5.1 1.6 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 Sugar_tr PF00083.24 GAP92230.1 - 3.4e-94 316.3 23.6 3.8e-94 316.1 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP92230.1 - 2.4e-23 82.6 45.1 7.5e-23 81.0 24.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 GAP92230.1 - 0.83 10.2 8.2 0.048 14.2 1.9 2.3 2 1 0 2 2 2 0 Phage holin family 2 Trp_oprn_chp PF09534.10 GAP92230.1 - 1.3 8.8 7.9 0.26 11.1 1.0 2.5 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM40 PF15817.5 GAP92230.1 - 2.5 7.9 7.9 1.3 8.8 0.2 3.1 3 0 0 3 3 3 0 Transmembrane protein 40 family Gp_dh_C PF02800.20 GAP92231.1 - 2.9e-54 182.9 0.1 4.3e-54 182.4 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 GAP92231.1 - 3.1e-27 94.9 0.1 1e-26 93.2 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Zn_clus PF00172.18 GAP92232.1 - 0.011 15.9 8.9 0.02 15.0 8.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pribosyltran PF00156.27 GAP92233.1 - 9.8e-07 28.4 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Oxidored-like PF09791.9 GAP92234.1 - 7.6e-23 79.9 4.4 7.6e-23 79.9 4.4 2.3 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal K_channel_TID PF07941.11 GAP92234.1 - 0.5 10.9 7.6 1.8 9.1 7.6 2.0 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Ndc1_Nup PF09531.10 GAP92234.1 - 0.52 8.9 11.9 0.62 8.7 11.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 GAP92234.1 - 1.1 7.8 12.4 1.2 7.7 12.4 1.3 1 0 0 1 1 1 0 Hamartin protein Apt1 PF10351.9 GAP92234.1 - 2.8 6.7 7.8 3.7 6.3 7.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SRP-alpha_N PF04086.13 GAP92234.1 - 9.1 6.1 11.3 48 3.7 9.1 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal UBA_3 PF09288.10 GAP92235.1 - 0.0032 17.3 0.1 0.0074 16.1 0.0 1.6 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain CorA PF01544.18 GAP92236.1 - 0.037 13.3 1.0 0.05 12.9 0.1 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein bMG6 PF17962.1 GAP92238.1 - 0.46 10.6 4.2 1.3 9.2 4.2 1.7 1 0 0 1 1 1 0 Bacterial macroglobulin domain 6 DUF2777 PF10949.8 GAP92238.1 - 3.1 7.4 5.5 1.7 8.3 3.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2777) NmrA PF05368.13 GAP92239.1 - 2.5e-32 112.3 0.0 4.3e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP92239.1 - 5.1e-16 59.1 0.1 8.7e-15 55.1 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP92239.1 - 6e-06 25.9 0.1 0.00011 21.7 0.1 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAO_M PF16350.5 GAP92239.1 - 0.041 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase central domain Acetyltransf_8 PF13523.6 GAP92240.1 - 2e-40 137.8 0.2 3.1e-40 137.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MCU PF04678.13 GAP92241.1 - 4e-23 82.4 1.2 5.2e-23 82.0 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial calcium uniporter RNase_J_C PF17770.1 GAP92241.1 - 0.31 12.1 1.3 2.4 9.3 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain Ras PF00071.22 GAP92242.1 - 5.4e-41 139.9 0.0 8.2e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 GAP92242.1 - 3.9e-32 110.7 16.9 1.3e-12 48.1 1.5 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP92242.1 - 1.4e-19 69.9 8.6 5.2e-08 33.0 0.0 5.8 1 1 5 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAP92242.1 - 3.9e-19 68.8 7.1 3.7e-05 24.2 0.1 4.9 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP92242.1 - 5.3e-16 57.1 5.4 0.47 11.2 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 GAP92242.1 - 1.5e-14 53.7 18.0 0.027 14.9 0.2 6.7 6 0 0 6 6 6 4 Ankyrin repeat Roc PF08477.13 GAP92242.1 - 3.3e-13 49.9 0.0 5.7e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF676 PF05057.14 GAP92242.1 - 7.2e-06 25.7 0.0 0.001 18.6 0.0 2.4 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Arf PF00025.21 GAP92242.1 - 3.2e-05 23.5 0.0 5.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Hydrolase_4 PF12146.8 GAP92242.1 - 0.085 12.1 0.0 0.21 10.8 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 GAP92242.1 - 0.093 12.4 0.2 0.25 11.1 0.1 1.7 2 0 0 2 2 2 0 PGAP1-like protein Snf7 PF03357.21 GAP92243.1 - 3.5e-39 134.2 1.5 4.1e-39 134.0 1.5 1.0 1 0 0 1 1 1 1 Snf7 DUF848 PF05852.11 GAP92243.1 - 0.0022 18.1 0.8 0.0022 18.1 0.8 1.8 2 0 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.12 GAP92243.1 - 0.01 16.3 0.5 4.2 7.9 0.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.6 GAP92243.1 - 0.012 15.6 3.6 0.023 14.7 3.6 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF4407 PF14362.6 GAP92243.1 - 0.024 14.0 2.1 0.031 13.7 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliD_C PF07195.12 GAP92243.1 - 0.036 13.5 1.8 0.41 10.0 0.0 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Prefoldin_2 PF01920.20 GAP92243.1 - 0.041 13.8 2.1 1.3 9.0 0.0 3.0 2 1 1 3 3 3 0 Prefoldin subunit FapA PF03961.13 GAP92243.1 - 0.065 11.8 0.5 0.11 11.1 0.4 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Trans_reg_C PF00486.28 GAP92243.1 - 0.1 12.7 0.6 22 5.2 0.1 3.0 2 1 0 3 3 3 0 Transcriptional regulatory protein, C terminal DUF5082 PF16888.5 GAP92243.1 - 0.19 12.0 2.0 0.39 11.0 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DASH_Spc19 PF08287.11 GAP92243.1 - 0.28 11.1 4.0 0.62 9.9 4.0 1.6 1 1 0 1 1 1 0 Spc19 Spc7 PF08317.11 GAP92243.1 - 0.5 9.2 4.6 6.7 5.5 2.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein WD40 PF00400.32 GAP92244.1 - 2.6e-27 94.5 5.6 0.00012 22.8 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 GAP92244.1 - 1.3e-13 50.6 2.9 1.4e-13 50.5 1.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 GAP92244.1 - 1.8e-08 34.1 0.1 1.8e-08 34.1 0.1 1.9 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 GAP92244.1 - 3.8e-08 33.5 0.0 0.033 14.5 0.0 3.6 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 GAP92244.1 - 0.097 12.0 0.0 1.2 8.4 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 GAP92244.1 - 0.21 10.2 0.5 0.9 8.1 0.0 2.1 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PH_10 PF15411.6 GAP92245.1 - 1.8e-39 134.8 1.1 3.4e-39 133.9 1.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 GAP92245.1 - 4e-31 108.7 0.6 7e-31 107.9 0.1 1.7 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.11 GAP92245.1 - 3e-29 101.1 0.0 6.5e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 GAP92245.1 - 8.1e-10 38.5 0.0 1.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 PB1 domain MFS_1 PF07690.16 GAP92247.1 - 1.4e-24 86.7 52.4 5.8e-14 51.8 24.0 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Med18 PF09637.10 GAP92248.1 - 1.6e-27 97.0 0.0 1.9e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Med18 protein T4SS_TraI PF16932.5 GAP92248.1 - 0.088 12.0 0.5 0.34 10.0 0.0 1.9 2 0 0 2 2 2 0 Type IV secretory system, conjugal DNA-protein transfer DUF688 PF05097.12 GAP92248.1 - 0.62 9.2 1.8 0.89 8.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Ank_2 PF12796.7 GAP92249.1 - 3.5e-81 267.8 3.4 6.6e-19 68.3 0.0 7.3 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 GAP92249.1 - 4.7e-62 203.9 2.6 5.6e-06 26.6 0.0 14.1 13 1 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 GAP92249.1 - 2.4e-54 174.9 2.7 2.5e-05 24.3 0.0 14.0 14 0 0 14 14 14 10 Ankyrin repeat Ank_4 PF13637.6 GAP92249.1 - 1.2e-52 175.6 3.4 5.4e-11 42.8 0.0 10.3 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP92249.1 - 1.9e-39 133.2 2.7 3.1e-07 30.5 0.1 8.7 4 2 5 9 9 9 8 Ankyrin repeats (many copies) NACHT PF05729.12 GAP92249.1 - 1e-06 28.8 0.0 4.8e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 GAP92249.1 - 0.00082 19.7 0.0 0.0024 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain SesA PF17107.5 GAP92249.1 - 0.0016 18.6 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Mur_ligase PF01225.25 GAP92249.1 - 0.0064 16.8 0.0 26 5.2 0.0 5.1 2 1 3 6 6 6 0 Mur ligase family, catalytic domain Mic1 PF07035.12 GAP92249.1 - 0.024 14.4 0.6 43 3.8 0.0 4.8 2 1 3 6 6 6 0 Colon cancer-associated protein Mic1-like AAA PF00004.29 GAP92249.1 - 0.054 13.9 0.2 0.19 12.1 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Mtc PF03820.17 GAP92250.1 - 7.4e-103 343.9 0.0 8.9e-103 343.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Aa_trans PF01490.18 GAP92251.1 - 2e-38 132.2 32.3 2.3e-38 132.0 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 GAP92251.1 - 0.4 9.5 47.4 44 2.7 47.4 2.3 1 1 0 1 1 1 0 Amino acid permease Pro_dh PF01619.18 GAP92253.1 - 3.4e-25 89.2 0.0 9.9e-25 87.7 0.0 1.6 1 1 0 1 1 1 1 Proline dehydrogenase Halo_GVPC PF05465.13 GAP92253.1 - 0.028 14.7 2.8 0.028 14.7 2.8 2.0 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF3372 PF11852.8 GAP92254.1 - 0.2 11.1 0.1 0.38 10.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Aldedh PF00171.22 GAP92255.1 - 1.8e-95 320.2 0.0 2e-95 320.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4380 PF14315.6 GAP92255.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) Fungal_trans PF04082.18 GAP92256.1 - 1.6e-08 33.9 0.1 3.9e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP92256.1 - 2.4e-08 34.0 13.6 5e-08 32.9 13.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 GAP92257.1 - 3.8e-49 167.7 0.0 5e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DHH PF01368.20 GAP92259.1 - 4.9e-08 33.1 0.4 1e-07 32.1 0.4 1.5 1 0 0 1 1 1 1 DHH family NUDIX PF00293.28 GAP92260.1 - 9.3e-16 58.1 0.1 1.3e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Aminotran_5 PF00266.19 GAP92260.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V SAPS PF04499.15 GAP92261.1 - 8.4e-187 621.8 0.0 5.6e-186 619.1 0.0 2.3 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Condensation PF00668.20 GAP92262.1 - 1.9e-79 267.5 4.1 3.3e-31 108.5 0.0 3.7 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 GAP92262.1 - 1.8e-28 99.4 0.0 7.3e-28 97.3 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 GAP92262.1 - 1.6e-12 47.6 3.1 1.8e-05 25.0 0.1 3.5 3 0 0 3 3 3 2 Phosphopantetheine attachment site AA_permease PF00324.21 GAP92264.1 - 2.3e-143 478.3 47.8 2.7e-143 478.0 47.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP92264.1 - 3.5e-37 128.3 48.8 4.8e-37 127.8 48.8 1.1 1 0 0 1 1 1 1 Amino acid permease YrhC PF14143.6 GAP92264.1 - 1.6 8.9 14.5 0.94 9.6 0.7 4.1 4 0 0 4 4 4 0 YrhC-like protein MFS_1 PF07690.16 GAP92265.1 - 1.6e-33 116.1 24.4 8e-32 110.5 27.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 GAP92265.1 - 0.11 12.8 0.4 0.11 12.8 0.4 4.3 5 1 1 6 6 6 0 Protein of unknown function (DUF2530) BTP PF05232.12 GAP92265.1 - 0.12 12.4 1.9 0.54 10.4 0.3 2.9 2 0 0 2 2 2 0 Chlorhexidine efflux transporter GCFC PF07842.12 GAP92266.1 - 8.9e-72 242.0 1.7 1.1e-71 241.6 0.6 1.8 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 GAP92266.1 - 4.4e-14 52.1 2.0 4e-13 49.0 0.5 2.6 2 0 0 2 2 2 1 G-patch domain TIP_N PF12457.8 GAP92266.1 - 3.1e-12 46.8 5.7 3.1e-12 46.8 5.7 4.0 3 1 1 4 4 4 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 GAP92266.1 - 4e-05 23.6 0.5 4e-05 23.6 0.5 2.6 3 0 0 3 3 3 1 G-patch domain DUF2938 PF11158.8 GAP92266.1 - 0.011 15.2 0.3 0.021 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) Sld5 PF05916.11 GAP92267.1 - 2.2e-18 66.7 0.0 3.1e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.18 GAP92268.1 - 2.3e-37 127.2 0.5 4.6e-37 126.3 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 GAP92268.1 - 2.3e-30 104.9 2.4 4e-30 104.1 2.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Atrophin-1 PF03154.15 GAP92269.1 - 4.5 5.4 7.1 0.26 9.6 2.0 1.5 2 0 0 2 2 2 0 Atrophin-1 family SET PF00856.28 GAP92270.1 - 0.00036 21.0 0.0 0.0005 20.5 0.0 1.3 1 0 0 1 1 1 1 SET domain Glyco_hydro_61 PF03443.14 GAP92271.1 - 7.5e-62 208.9 0.4 1.2e-61 208.3 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 GAP92271.1 - 5.1e-13 48.7 11.5 1.5e-12 47.2 11.5 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.11 GAP92271.1 - 2.2 6.2 7.8 2.4 6.1 7.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NAD_binding_1 PF00175.21 GAP92273.1 - 6.2e-07 30.0 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MOSC PF03473.17 GAP92273.1 - 1.3e-06 28.4 0.1 4.4e-06 26.7 0.1 1.9 1 1 1 2 2 2 1 MOSC domain Fer2 PF00111.27 GAP92273.1 - 1.7e-06 27.9 0.3 3.1e-06 27.0 0.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 GAP92273.1 - 0.0008 19.7 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain p450 PF00067.22 GAP92275.1 - 1.5e-62 211.8 0.0 2e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ndc1_Nup PF09531.10 GAP92276.1 - 0.23 10.1 11.2 0.23 10.1 11.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SHR-BD PF06650.12 GAP92277.1 - 5.9e-99 330.8 0.1 1.2e-94 316.7 0.0 3.3 4 0 0 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 GAP92277.1 - 7e-88 294.4 0.7 2e-85 286.4 0.0 4.0 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 GAP92277.1 - 8.1e-79 264.4 10.9 1e-74 251.0 2.5 6.2 6 1 0 6 6 6 2 Repeating coiled region of VPS13 VPS13_C PF16909.5 GAP92277.1 - 3e-72 242.1 10.3 4.5e-69 231.8 0.4 3.2 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 GAP92277.1 - 6.6e-40 135.8 0.2 2.6e-39 133.9 0.0 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 GAP92277.1 - 5.6e-07 29.8 0.0 2.3e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF3429 PF11911.8 GAP92278.1 - 2.1e-43 148.0 12.1 2.8e-43 147.6 12.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Peptidase_S49_N PF08496.10 GAP92278.1 - 0.034 14.2 2.6 0.055 13.5 2.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HTH_36 PF13730.6 GAP92278.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2514 PF10721.9 GAP92278.1 - 8.1 6.5 9.0 15 5.6 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) NAD_binding_1 PF00175.21 GAP92279.1 - 1.1e-12 48.5 0.0 3.2e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.22 GAP92279.1 - 1.4e-07 32.1 0.0 2.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 GAP92279.1 - 1.1e-05 25.7 0.0 2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 GAP92279.1 - 4.6e-05 23.4 0.0 0.00012 22.0 0.0 1.6 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 GAP92279.1 - 0.00026 21.1 0.3 0.0062 16.7 0.4 2.7 2 1 1 3 3 3 1 Ferric reductase NAD binding domain ketoacyl-synt PF00109.26 GAP92280.1 - 4.1e-73 246.1 0.0 7.7e-73 245.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 GAP92280.1 - 4.6e-44 150.8 0.0 7.3e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP92280.1 - 3.5e-43 148.3 0.0 9.9e-43 146.8 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 GAP92280.1 - 1.2e-40 139.3 0.0 2.6e-40 138.3 0.0 1.6 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 GAP92280.1 - 6.4e-31 106.8 0.0 1.6e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 GAP92280.1 - 6.3e-13 49.2 0.0 2e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAP92280.1 - 4.3e-06 26.3 0.0 1.7e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 GAP92280.1 - 8.4e-05 22.8 0.0 0.00031 21.0 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 GAP92280.1 - 0.0045 17.6 0.0 0.2 12.4 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Thiolase_N PF00108.23 GAP92280.1 - 0.0077 15.6 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.12 GAP92280.1 - 0.015 16.0 0.1 0.12 13.2 0.0 2.7 3 0 0 3 3 1 0 Methyltransferase domain KRTAP PF11759.8 GAP92280.1 - 0.23 12.1 7.8 0.74 10.4 7.8 1.8 1 0 0 1 1 1 0 Keratin-associated matrix PRKCSH PF07915.13 GAP92282.1 - 4.2e-20 72.5 0.0 1e-19 71.3 0.0 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 GAP92282.1 - 0.068 12.9 0.1 6.9 6.3 0.1 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Cnn_1N PF07989.11 GAP92283.1 - 1.1e-06 28.7 4.8 3.1e-06 27.2 4.8 1.7 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 ADIP PF11559.8 GAP92283.1 - 1.8 8.6 6.1 9 6.4 2.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tmemb_cc2 PF10267.9 GAP92283.1 - 5.5 6.0 12.3 28 3.7 12.3 2.0 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein NARP1 PF12569.8 GAP92285.1 - 5.9 5.7 9.9 6.7 5.5 9.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CLN3 PF02487.17 GAP92286.1 - 9e-161 535.4 6.9 1e-160 535.2 6.9 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 GAP92286.1 - 9.6e-06 24.7 32.9 9.7e-05 21.4 13.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_U4 PF03419.13 GAP92286.1 - 4.4 6.5 17.1 0.032 13.5 7.9 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DUF2183 PF09949.9 GAP92287.1 - 2.5e-35 120.8 0.0 2e-34 117.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF4837 PF16125.5 GAP92287.1 - 0.0027 16.8 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4837) RRM_1 PF00076.22 GAP92288.1 - 5.5e-24 83.8 0.5 5.6e-11 42.1 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAP92288.1 - 0.00029 20.4 0.0 0.0066 16.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 GAP92288.1 - 0.0032 17.3 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) DUF1866 PF08952.11 GAP92288.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) ATP-synt_D PF01813.17 GAP92289.1 - 1.2e-70 237.3 0.9 1.6e-70 237.0 0.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.6 GAP92289.1 - 0.049 13.7 1.8 0.47 10.5 0.3 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 HtrL_YibB PF09612.10 GAP92289.1 - 0.091 12.3 0.2 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) PHM7_cyt PF14703.6 GAP92289.1 - 0.13 12.5 4.4 0.21 11.8 1.2 2.2 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_L6e PF01159.19 GAP92289.1 - 0.2 12.2 2.8 0.57 10.7 2.8 1.8 1 0 0 1 1 1 0 Ribosomal protein L6e CobA_CobO_BtuR PF02572.15 GAP92289.1 - 0.34 11.1 3.3 1 9.6 0.1 2.4 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP GAS PF13851.6 GAP92289.1 - 0.38 10.1 0.1 0.38 10.1 0.1 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF5446 PF17522.2 GAP92289.1 - 0.68 10.1 2.4 0.82 9.9 0.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5446) BLOC1_2 PF10046.9 GAP92289.1 - 1.7 9.0 5.5 12 6.3 0.0 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_14 PF13428.6 GAP92290.1 - 2.9e-13 49.4 26.0 0.31 12.0 0.1 12.0 10 2 2 12 12 12 4 Tetratricopeptide repeat Suf PF05843.14 GAP92290.1 - 3.8e-13 50.1 9.2 0.014 15.4 1.2 7.0 3 2 2 5 5 5 4 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 GAP92290.1 - 3.3e-07 30.3 10.5 0.88 9.6 0.0 7.1 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 GAP92290.1 - 2.4e-06 27.0 12.0 1.2e-05 24.6 0.7 4.6 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP92290.1 - 0.00019 21.4 8.1 0.06 13.6 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat RPN7 PF10602.9 GAP92290.1 - 0.00058 19.6 1.3 0.0093 15.7 0.2 3.5 4 1 0 4 4 4 1 26S proteasome subunit RPN7 TPR_12 PF13424.6 GAP92290.1 - 0.0065 16.7 7.6 2.7 8.3 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAP92290.1 - 0.011 15.8 13.2 4.5 7.6 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat NRDE-2 PF08424.10 GAP92290.1 - 0.014 14.6 0.2 0.014 14.6 0.2 6.0 2 2 2 5 5 5 0 NRDE-2, necessary for RNA interference SHNi-TPR PF10516.9 GAP92290.1 - 0.083 12.4 0.0 0.92 9.0 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_10 PF13374.6 GAP92290.1 - 0.15 11.9 5.0 1.3e+02 2.7 0.4 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAP92290.1 - 0.31 11.5 5.2 99 3.7 0.0 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAP92290.1 - 0.85 10.4 9.2 4 8.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat K_channel_TID PF07941.11 GAP92291.1 - 2.1 8.8 8.1 0.074 13.5 1.9 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain CDK2AP PF09806.9 GAP92291.1 - 5.1 7.1 7.8 5.6 7.0 7.8 1.2 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Nuf2 PF03800.14 GAP92293.1 - 9.6e-41 139.2 0.2 2.7e-40 137.7 0.0 1.9 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 GAP92293.1 - 2.8e-38 130.6 18.2 2.8e-38 130.6 18.2 4.3 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain Bacillus_HBL PF05791.11 GAP92293.1 - 0.059 13.2 17.3 0.089 12.6 1.8 3.1 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) BLOC1_2 PF10046.9 GAP92293.1 - 1.9 8.8 24.8 0.25 11.7 4.9 4.2 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PI3K_P85_iSH2 PF16454.5 GAP92293.1 - 6.3 6.4 37.9 0.24 11.0 3.4 4.4 1 1 3 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Thioredoxin PF00085.20 GAP92295.1 - 2.7e-24 85.1 0.1 3.2e-24 84.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAP92295.1 - 1.2e-05 25.7 0.2 0.00011 22.7 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 GAP92295.1 - 6.1e-05 22.8 0.0 7.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 GAP92295.1 - 7.2e-05 22.3 0.0 7.8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 GAP92295.1 - 0.001 19.4 0.0 0.014 15.7 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 GAP92295.1 - 0.0024 17.8 0.0 0.0026 17.6 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 GAP92295.1 - 0.0087 16.2 0.0 0.0098 16.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 GAP92295.1 - 0.011 15.4 0.1 0.02 14.6 0.1 1.5 1 1 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 GAP92295.1 - 0.014 15.6 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin AhpC-TSA PF00578.21 GAP92295.1 - 0.081 12.9 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_3 PF13192.6 GAP92295.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin domain Acetyltransf_9 PF13527.7 GAP92296.1 - 9.4e-08 32.2 0.1 7.8e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP92296.1 - 2.8e-05 24.3 0.1 4.5e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP92296.1 - 0.00028 21.3 0.0 0.00051 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 GAP92296.1 - 0.00029 20.8 0.0 0.00052 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 GAP92296.1 - 0.0069 16.5 0.0 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 GAP92296.1 - 0.073 13.0 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Pkinase PF00069.25 GAP92297.1 - 4.1e-46 157.5 0.0 5.6e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92297.1 - 5.5e-26 91.4 0.0 7.6e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 GAP92297.1 - 0.00032 20.1 0.0 0.00086 18.7 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 GAP92297.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_Tyr PF07714.17 GAP92298.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 GAP92298.1 - 0.04 13.3 0.0 0.26 10.6 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain Cu_bind_like PF02298.17 GAP92299.1 - 0.0097 15.9 0.0 0.053 13.5 0.0 2.0 2 0 0 2 2 2 1 Plastocyanin-like domain Big_9 PF17963.1 GAP92299.1 - 6.1 7.7 8.2 17 6.3 0.0 3.9 4 1 0 4 4 4 0 Bacterial Ig domain SUR7 PF06687.12 GAP92300.1 - 7.2e-23 81.3 5.5 9.5e-23 80.9 5.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family MARVEL PF01284.23 GAP92300.1 - 0.057 13.4 9.9 0.035 14.1 4.1 2.3 2 0 0 2 2 2 0 Membrane-associating domain DUF4239 PF14023.6 GAP92300.1 - 1.3 8.7 5.3 0.32 10.7 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) CD20 PF04103.15 GAP92300.1 - 2.5 8.2 12.8 0.042 13.9 4.1 2.2 2 1 0 2 2 2 0 CD20-like family Zn_clus PF00172.18 GAP92301.1 - 7.3e-07 29.2 8.7 1.7e-06 28.0 8.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP92301.1 - 0.016 14.2 1.4 0.084 11.9 0.1 2.4 2 1 0 2 2 2 0 Fungal specific transcription factor domain AFG1_ATPase PF03969.16 GAP92302.1 - 9.7e-97 324.1 0.0 1.9e-91 306.7 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 GAP92302.1 - 0.00012 22.5 0.1 0.051 14.0 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.18 GAP92302.1 - 0.00068 19.5 0.3 0.2 11.5 0.1 2.5 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 GAP92302.1 - 0.0039 17.2 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAP92302.1 - 0.0078 16.5 0.1 0.035 14.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 GAP92302.1 - 0.0082 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 GAP92302.1 - 0.0095 16.4 0.0 0.065 13.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAP92302.1 - 0.041 14.3 0.2 0.25 11.8 0.0 2.4 2 1 1 3 3 3 0 RNA helicase AAA_5 PF07728.14 GAP92302.1 - 0.043 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 GAP92302.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.8 1 1 0 1 1 1 0 NACHT domain MFS_1 PF07690.16 GAP92304.1 - 1.4e-11 43.9 43.9 3.5e-11 42.6 42.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily PolyA_pol PF01743.20 GAP92306.1 - 4.2e-26 91.8 0.1 9e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 GAP92306.1 - 1.6e-08 34.2 0.0 3.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 GAP92306.1 - 0.0068 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DUF1329 PF07044.11 GAP92306.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1329) His_Me_b4a2 PF18275.1 GAP92306.1 - 0.14 12.2 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain Adaptin_N PF01602.20 GAP92308.1 - 1e-99 334.5 0.0 1.3e-99 334.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 GAP92308.1 - 5.5e-15 55.8 0.1 3.8e-14 53.1 0.0 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 GAP92308.1 - 1.4e-10 40.4 1.5 0.045 14.0 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 GAP92308.1 - 1.6e-10 41.2 3.1 2.8e-05 24.4 0.0 4.9 3 2 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 GAP92308.1 - 0.00012 22.4 5.2 0.077 13.5 0.1 4.4 4 0 0 4 4 4 1 HEAT-like repeat Cohesin_HEAT PF12765.7 GAP92308.1 - 0.0061 16.8 0.6 0.24 11.7 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Nop14 PF04147.12 GAP92308.1 - 0.011 14.0 24.5 0.016 13.4 24.5 1.2 1 0 0 1 1 1 0 Nop14-like family CRISPR_Cse2 PF09485.10 GAP92308.1 - 0.032 14.8 0.6 24 5.4 0.4 3.6 3 0 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) SDA1 PF05285.12 GAP92308.1 - 0.057 12.9 22.4 0.11 11.8 22.4 1.4 1 0 0 1 1 1 0 SDA1 VIT1 PF01988.19 GAP92308.1 - 0.098 12.5 0.2 0.23 11.3 0.2 1.7 1 0 0 1 1 1 0 VIT family RNA_pol_Rpc4 PF05132.14 GAP92308.1 - 0.57 10.6 3.2 1.1 9.7 3.2 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tim54 PF11711.8 GAP92308.1 - 4.1 6.1 6.2 6 5.5 6.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.15 GAP92308.1 - 6.5 5.4 7.2 9.7 4.8 7.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NAD_binding_2 PF03446.15 GAP92309.1 - 1.5e-32 113.0 0.1 2.2e-32 112.4 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAP92309.1 - 1.3e-27 96.5 0.2 2.6e-27 95.5 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Reprolysin_5 PF13688.6 GAP92310.1 - 0.017 15.3 1.2 0.049 13.8 1.2 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M64 PF09471.10 GAP92310.1 - 0.051 13.1 0.3 0.15 11.5 0.1 1.9 1 1 1 2 2 2 0 IgA Peptidase M64 Zincin_1 PF06262.11 GAP92310.1 - 0.18 11.9 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase KilA-N PF04383.13 GAP92311.1 - 0.0013 18.5 0.4 0.029 14.2 0.0 2.8 2 1 0 2 2 2 1 KilA-N domain GTSE1_N PF15259.6 GAP92311.1 - 0.8 9.9 6.2 1.4 9.1 6.2 1.4 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Rho_GDI PF02115.17 GAP92312.1 - 5.7e-61 205.7 0.1 9.1e-61 205.0 0.1 1.3 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.28 GAP92313.1 - 1.4e-36 126.9 0.5 1.8e-36 126.6 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PI31_Prot_N PF11566.8 GAP92315.1 - 7.3e-58 195.0 0.0 9.4e-58 194.6 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 GAP92315.1 - 3.5e-15 56.9 22.4 3.5e-15 56.9 22.4 3.0 3 1 0 3 3 3 1 PI31 proteasome regulator HORMA PF02301.18 GAP92316.1 - 9.8e-11 41.6 0.0 1e-09 38.3 0.0 1.9 1 1 0 1 1 1 1 HORMA domain FAM176 PF14851.6 GAP92316.1 - 0.057 13.1 0.9 0.09 12.4 0.9 1.3 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 GAP92316.1 - 0.099 12.1 3.8 0.11 11.8 3.8 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 GAP92316.1 - 0.12 12.3 1.9 0.15 12.0 1.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 GAP92316.1 - 0.13 10.5 3.2 0.17 10.2 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 GAP92316.1 - 0.26 9.3 12.9 0.35 8.9 12.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 GAP92316.1 - 1.5 6.8 9.1 2.2 6.3 9.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 GAP92316.1 - 2.5 6.2 8.3 3.2 5.9 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family S-antigen PF05756.11 GAP92316.1 - 3.6 8.0 5.5 6.4 7.2 5.5 1.4 1 0 0 1 1 1 0 S-antigen protein DUF4637 PF15470.6 GAP92316.1 - 8.1 6.1 7.9 12 5.5 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) IBN_N PF03810.19 GAP92317.1 - 5.1e-09 35.9 0.0 3.2e-08 33.4 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 GAP92317.1 - 4.2e-06 26.9 0.6 0.0027 17.8 0.0 3.7 4 0 0 4 4 4 2 Exportin 1-like protein CAS_CSE1 PF03378.15 GAP92317.1 - 0.00026 19.6 0.0 0.00072 18.2 0.0 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus RhoGEF PF00621.20 GAP92318.1 - 1.2e-24 87.6 0.2 4.7e-24 85.6 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 GAP92318.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) Nod1 PF17114.5 GAP92318.1 - 0.036 14.2 0.0 0.15 12.2 0.0 2.2 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 Baculo_PEP_C PF04513.12 GAP92318.1 - 0.098 12.7 1.7 0.36 10.9 1.7 2.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF148 PF02520.17 GAP92318.1 - 0.11 12.7 5.0 0.065 13.4 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 RhoGAP PF00620.27 GAP92318.1 - 0.12 12.2 0.1 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 RhoGAP domain Macoilin PF09726.9 GAP92318.1 - 0.46 9.0 11.0 0.77 8.3 11.0 1.3 1 0 0 1 1 1 0 Macoilin family V-ATPase_G_2 PF16999.5 GAP92318.1 - 4.7 7.7 9.6 5.9 7.4 4.7 2.9 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit Fzo_mitofusin PF04799.13 GAP92318.1 - 5.3 6.6 7.4 13 5.3 0.6 3.5 1 1 2 3 3 3 0 fzo-like conserved region Dcc1 PF09724.9 GAP92319.1 - 1.5e-10 40.9 0.0 1.7e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 HTH_25 PF13413.6 GAP92319.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain IBR PF01485.21 GAP92320.1 - 0.00065 19.9 6.3 0.00065 19.9 6.3 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 GAP92320.1 - 0.0022 18.0 2.6 0.0022 18.0 2.6 2.8 3 1 0 3 3 3 1 RING-type zinc-finger Acetyltransf_9 PF13527.7 GAP92321.1 - 0.039 14.0 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Cpn60_TCP1 PF00118.24 GAP92322.1 - 3e-151 504.4 14.7 3.4e-151 504.2 14.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Metallophos PF00149.28 GAP92323.1 - 4.4e-14 53.5 0.1 8.7e-14 52.5 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAP92323.1 - 2.6e-07 31.0 0.0 4e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain zf_C2H2_10 PF18414.1 GAP92325.1 - 1.7 8.2 3.6 18 5.0 0.6 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger MMS1_N PF10433.9 GAP92326.1 - 1.4e-113 380.1 0.0 2.1e-113 379.5 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 GAP92326.1 - 6.1e-66 222.9 0.1 2.5e-65 220.9 0.0 2.0 3 0 0 3 3 3 1 CPSF A subunit region Rieske PF00355.26 GAP92326.1 - 4.4e-10 39.4 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 GAP92326.1 - 1.5e-08 35.0 0.2 3.8e-08 33.7 0.2 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region GNT-I PF03071.15 GAP92326.1 - 0.082 11.7 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 GNT-I family Ank_2 PF12796.7 GAP92327.1 - 5.9e-56 187.0 7.2 2.7e-18 66.3 0.2 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP92327.1 - 1.2e-47 159.7 7.8 6.2e-10 39.4 0.3 5.8 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP92327.1 - 6.8e-40 130.5 4.3 0.00022 21.4 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank PF00023.30 GAP92327.1 - 1.5e-35 120.1 16.5 0.00066 20.0 0.1 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 GAP92327.1 - 4.1e-27 93.9 13.5 2e-07 31.1 0.0 7.3 2 2 4 7 7 7 7 Ankyrin repeats (many copies) MTP18 PF10558.9 GAP92328.1 - 9.2e-84 279.6 0.1 1.2e-83 279.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.16 GAP92329.1 - 1.2e-22 79.7 24.2 3.7e-12 46.2 10.1 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 GAP92329.1 - 0.0096 16.1 16.2 0.011 15.9 2.3 2.5 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 GAP92329.1 - 0.034 14.5 13.7 0.16 12.4 4.6 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Rad4 PF03835.15 GAP92330.1 - 6.2e-36 123.3 0.1 2.5e-35 121.3 0.1 2.1 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 GAP92330.1 - 2.1e-27 95.3 0.4 4.3e-27 94.3 0.4 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 GAP92330.1 - 7.2e-20 70.6 0.8 1.5e-19 69.6 0.8 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 GAP92330.1 - 1.5e-13 51.5 0.2 1.5e-13 51.5 0.2 5.3 7 0 0 7 7 7 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 GAP92330.1 - 0.0016 18.9 0.0 0.0055 17.2 0.0 1.9 1 1 0 1 1 1 1 Transglutaminase-like superfamily PhzC-PhzF PF02567.16 GAP92332.1 - 6.6e-34 117.7 1.1 2.9e-32 112.3 1.1 2.1 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Glyco_trans_4_4 PF13579.6 GAP92332.1 - 0.098 13.1 4.6 0.82 10.1 0.5 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Ion_trans PF00520.31 GAP92333.1 - 4.2e-06 26.2 25.0 4.2e-06 26.2 25.0 2.0 2 1 0 2 2 2 1 Ion transport protein PNTB_4TM PF12769.7 GAP92333.1 - 0.00029 21.2 0.3 0.00083 19.8 0.3 1.7 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch DUF1180 PF06679.12 GAP92334.1 - 0.00034 21.1 6.4 0.00069 20.1 5.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) Glycophorin_A PF01102.18 GAP92334.1 - 0.0012 19.1 0.8 0.0024 18.1 0.8 1.5 1 0 0 1 1 1 1 Glycophorin A Syndecan PF01034.20 GAP92334.1 - 0.065 13.2 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 GAP92334.1 - 0.089 13.7 0.0 0.44 11.4 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Sporozoite_P67 PF05642.11 GAP92334.1 - 0.14 10.2 20.8 0.22 9.5 20.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apt1 PF10351.9 GAP92334.1 - 0.18 10.7 6.6 0.25 10.1 6.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 GAP92334.1 - 1.1 8.6 3.1 1.6 8.1 3.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF908 PF06012.12 GAP92334.1 - 4 6.7 12.7 6.6 6.0 12.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PAP1 PF08601.10 GAP92334.1 - 7.4 6.2 18.0 13 5.4 18.0 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 TMEM154 PF15102.6 GAP92334.1 - 8 6.4 10.6 38 4.2 10.6 2.0 1 1 0 1 1 1 0 TMEM154 protein family Aldose_epim PF01263.20 GAP92336.1 - 3.9e-46 157.7 0.2 4.5e-46 157.5 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Methyltransf_16 PF10294.9 GAP92337.1 - 7.5e-25 87.7 0.0 1.1e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 GAP92337.1 - 6.4e-09 35.6 0.0 8.4e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAP92337.1 - 1.8e-05 24.4 0.1 2.7e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 GAP92337.1 - 8.3e-05 22.4 0.0 0.0002 21.1 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_25 PF13649.6 GAP92337.1 - 0.0001 23.0 0.2 0.00022 21.9 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP92337.1 - 0.0097 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP92337.1 - 0.022 15.5 0.0 0.042 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 GAP92337.1 - 0.11 12.5 0.2 0.27 11.2 0.2 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Cons_hypoth95 PF03602.15 GAP92337.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF938 PF06080.12 GAP92337.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 GAP92337.1 - 0.19 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Bromodomain PF00439.25 GAP92339.1 - 8.8e-35 118.6 0.9 1.7e-16 60.0 0.6 2.7 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 GAP92339.1 - 2e-13 50.3 0.3 2e-13 50.3 0.3 2.5 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation Methyltrans_Mon PF14314.6 GAP92339.1 - 0.17 9.9 0.6 0.26 9.3 0.6 1.2 1 0 0 1 1 1 0 Virus-capping methyltransferase Utp12 PF04003.12 GAP92340.1 - 9.4e-25 87.0 0.0 1.4e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family MgsA_C PF12002.8 GAP92341.1 - 2.3e-60 203.3 0.0 5.4e-60 202.1 0.0 1.6 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 GAP92341.1 - 6.4e-23 80.9 0.0 1.6e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 GAP92341.1 - 2.1e-14 54.1 0.1 4.1e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 GAP92341.1 - 1.1e-09 38.2 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 GAP92341.1 - 8.9e-07 28.8 0.1 3.4e-05 23.6 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 GAP92341.1 - 2.3e-06 28.1 0.4 0.0031 17.9 0.0 3.1 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 GAP92341.1 - 8.8e-06 26.0 0.1 2.5e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAP92341.1 - 0.00013 21.4 0.1 0.086 12.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAP92341.1 - 0.00068 19.7 0.1 0.044 13.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 GAP92341.1 - 0.00075 19.5 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAP92341.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TRAF6_Z2 PF18048.1 GAP92341.1 - 0.0053 16.8 0.2 0.0094 16.0 0.2 1.4 1 0 0 1 1 1 1 TNF receptor-associated factor 6 zinc finger 2 ResIII PF04851.15 GAP92341.1 - 0.0053 16.8 0.3 0.42 10.6 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.13 GAP92341.1 - 0.0058 15.9 0.0 0.0092 15.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain DNA_pol3_delta2 PF13177.6 GAP92341.1 - 0.012 15.5 0.0 0.54 10.0 0.1 2.4 1 1 1 2 2 2 0 DNA polymerase III, delta subunit TniB PF05621.11 GAP92341.1 - 0.013 14.9 0.0 0.033 13.6 0.0 1.6 1 1 0 1 1 1 0 Bacterial TniB protein AAA_3 PF07726.11 GAP92341.1 - 0.015 15.1 0.0 0.13 12.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 GAP92341.1 - 0.016 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 GAP92341.1 - 0.025 14.9 0.1 0.16 12.3 0.1 2.0 1 1 1 2 2 2 0 AAA domain CPT PF07931.12 GAP92341.1 - 0.03 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein zf_C2H2_13 PF18508.1 GAP92341.1 - 0.046 13.3 0.6 0.089 12.4 0.6 1.5 1 0 0 1 1 1 0 Zinc finger domain SKI PF01202.22 GAP92341.1 - 0.048 13.8 0.1 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.6 GAP92341.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 GAP92341.1 - 0.085 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 GAP92341.1 - 0.15 11.8 0.2 0.52 10.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain Fe-S_biosyn PF01521.20 GAP92342.1 - 8.5e-20 71.0 0.0 1.1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1741 PF08427.10 GAP92343.1 - 9.3e-86 287.3 0.4 9.3e-86 287.3 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) RT_RNaseH_2 PF17919.1 GAP92343.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase 2OG-FeII_Oxy_3 PF13640.6 GAP92344.1 - 1.3e-08 35.6 0.4 2.5e-08 34.7 0.4 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Chlor_dismutase PF06778.12 GAP92344.1 - 0.27 10.8 0.4 0.42 10.1 0.4 1.2 1 0 0 1 1 1 0 Chlorite dismutase zf_CCCH_4 PF18345.1 GAP92346.1 - 0.00024 21.0 6.2 0.00024 21.0 6.2 2.8 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH PF00642.24 GAP92346.1 - 0.0011 18.9 1.3 0.0011 18.9 1.3 3.2 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 GAP92346.1 - 0.0096 15.7 1.7 0.0096 15.7 1.7 3.2 4 0 0 4 4 4 1 CCCH-type zinc finger Torus PF16131.5 GAP92346.1 - 0.048 14.4 0.6 0.18 12.5 0.0 2.2 2 0 0 2 2 2 0 Torus domain KNOX2 PF03791.13 GAP92346.1 - 0.05 13.1 0.4 0.76 9.3 0.2 2.6 2 0 0 2 2 2 0 KNOX2 domain ADAM_CR_2 PF17771.1 GAP92346.1 - 2.3 8.8 9.9 1.1 9.8 1.6 3.3 3 0 0 3 3 3 0 ADAM cysteine-rich domain Beta-lactamase PF00144.24 GAP92347.1 - 1.4e-50 172.4 0.0 2.2e-50 171.8 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 GAP92347.1 - 7.3e-11 42.5 0.2 1.4e-10 41.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF2271 PF10029.9 GAP92347.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Mannosidase_ig PF17786.1 GAP92348.1 - 3.2e-20 72.5 0.4 2.1e-19 69.9 0.5 2.2 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 GAP92348.1 - 8.7e-07 29.6 0.0 4e-06 27.5 0.0 2.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 GAP92348.1 - 0.00033 20.3 0.0 0.00096 18.9 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 GAP92348.1 - 0.0014 17.8 0.0 0.0035 16.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 GAP92348.1 - 0.03 14.2 0.9 0.42 10.5 0.0 3.0 4 0 0 4 4 4 0 Glycosyl hydrolases family 2, sugar binding domain Zn_clus PF00172.18 GAP92349.1 - 6.9e-06 26.1 8.5 6.9e-06 26.1 8.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Plasmodium_Vir PF05795.11 GAP92349.1 - 0.078 12.4 0.8 0.14 11.6 0.8 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Med15 PF09606.10 GAP92349.1 - 0.25 10.0 12.7 0.36 9.4 12.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CCDC53 PF10152.9 GAP92349.1 - 0.5 10.8 3.3 1.1 9.7 3.3 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Ilar_coat PF01787.16 GAP92349.1 - 1.4 8.7 4.9 2.3 7.9 4.9 1.3 1 0 0 1 1 1 0 Ilarvirus coat protein DUF3306 PF11748.8 GAP92349.1 - 7.2 7.5 9.1 15 6.5 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) polyprenyl_synt PF00348.17 GAP92350.1 - 4.4e-65 219.3 0.0 5.7e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Translin PF01997.16 GAP92350.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Translin family p450 PF00067.22 GAP92351.1 - 2.1e-45 155.4 0.1 2.3e-45 155.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 SQHop_cyclase_C PF13243.6 GAP92352.1 - 0.014 14.5 0.3 0.95 8.5 0.1 3.1 3 0 0 3 3 3 0 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 GAP92352.1 - 0.049 13.4 1.2 0.93 9.3 0.1 3.0 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat Fringe PF02434.16 GAP92353.1 - 4.8e-08 32.7 0.1 1.7e-06 27.7 0.1 2.5 2 1 0 2 2 2 1 Fringe-like DUF604 PF04646.12 GAP92353.1 - 0.00012 21.5 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 PAN_4 PF14295.6 GAP92353.1 - 0.002 18.0 2.8 0.0051 16.7 2.8 1.7 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.21 GAP92353.1 - 0.12 12.2 0.0 3.5 7.4 0.0 2.3 1 1 1 2 2 2 0 Galactosyltransferase PAN_1 PF00024.26 GAP92353.1 - 0.12 12.3 1.6 0.25 11.3 1.6 1.5 1 0 0 1 1 1 0 PAN domain DUF5608 PF18356.1 GAP92353.1 - 0.12 12.3 0.4 0.31 11.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5608) Annexin_like PF18411.1 GAP92353.1 - 0.14 12.4 0.0 6.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Annexin-like domain SKG6 PF08693.10 GAP92354.1 - 4.5e-06 26.0 1.0 4.5e-06 26.0 1.0 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 GAP92354.1 - 0.0022 18.1 3.0 0.0034 17.5 3.0 1.3 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.11 GAP92354.1 - 2.4 8.6 8.0 1.5 9.2 6.1 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SAP130_C PF16014.5 GAP92355.1 - 6.9 5.7 9.4 9.8 5.1 9.4 1.2 1 1 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Ank_2 PF12796.7 GAP92356.1 - 2.9e-24 85.4 0.1 7.6e-08 32.8 0.0 4.3 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP92356.1 - 3.3e-22 78.5 1.0 4.4e-07 30.3 0.0 7.4 5 3 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP92356.1 - 2.3e-21 73.6 0.8 5.6e-05 23.2 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 GAP92356.1 - 2.1e-19 69.3 5.1 7.2e-09 35.7 0.1 7.0 6 1 1 7 7 7 4 Ankyrin repeats (many copies) tRNA-synt_2b PF00587.25 GAP92356.1 - 1.2e-18 67.7 0.0 2.5e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 GAP92356.1 - 2.4e-17 62.9 0.0 4.7e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 GAP92356.1 - 6.7e-17 61.4 0.0 1.4e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Ank PF00023.30 GAP92356.1 - 2.2e-16 59.5 0.1 0.00042 20.6 0.0 7.3 7 0 0 7 7 7 2 Ankyrin repeat FAD_binding_4 PF01565.23 GAP92357.1 - 2.1e-19 69.6 0.3 4.2e-19 68.7 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP92357.1 - 8e-10 38.7 0.1 2e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like P53_tetramer PF07710.11 GAP92357.1 - 0.25 10.7 0.5 0.46 9.9 0.5 1.3 1 0 0 1 1 1 0 P53 tetramerisation motif DJ-1_PfpI PF01965.24 GAP92358.1 - 5.5e-13 49.1 0.0 6.5e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 GAP92358.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I KapB PF08810.10 GAP92359.1 - 9.6 6.4 7.2 7.2 6.8 1.4 2.8 1 1 2 3 3 3 0 Kinase associated protein B HECT PF00632.25 GAP92360.1 - 5.1e-74 249.5 0.0 7e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Casc1_N PF15927.5 GAP92360.1 - 0.051 13.3 0.1 0.084 12.6 0.1 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF3712 PF12505.8 GAP92361.1 - 1.6e-05 25.2 0.0 0.00034 20.9 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3712) HlyE PF06109.13 GAP92361.1 - 0.011 15.1 0.1 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Haemolysin E (HlyE) Fringe PF02434.16 GAP92362.1 - 2.4e-06 27.2 0.1 0.003 17.1 0.2 3.0 2 1 0 2 2 2 2 Fringe-like DUF604 PF04646.12 GAP92362.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 PAN_1 PF00024.26 GAP92362.1 - 0.14 12.2 1.4 0.27 11.2 1.4 1.4 1 0 0 1 1 1 0 PAN domain S10_plectin PF03501.15 GAP92363.1 - 4.6e-42 142.0 0.1 5.6e-42 141.7 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Sde2_N_Ubi PF13019.6 GAP92364.1 - 1.4e-68 229.9 0.1 2.1e-68 229.3 0.1 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain His_Phos_1 PF00300.22 GAP92364.1 - 0.0045 16.7 1.1 0.0063 16.2 1.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MPM1 PF17234.2 GAP92364.1 - 0.07 13.4 6.5 0.12 12.6 6.5 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF2407 PF10302.9 GAP92364.1 - 0.41 11.2 1.9 5.6 7.6 0.9 2.5 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain adh_short PF00106.25 GAP92365.1 - 1.3e-39 135.6 0.0 1.8e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP92365.1 - 7.4e-28 97.7 0.2 9.9e-28 97.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP92365.1 - 4.8e-12 46.1 0.3 9.7e-12 45.2 0.3 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAP92365.1 - 0.00025 21.0 0.3 0.00053 19.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 GAP92365.1 - 0.0012 18.4 0.4 0.002 17.6 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 GAP92365.1 - 0.0046 16.1 0.1 0.0068 15.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain FTR_C PF02741.15 GAP92365.1 - 0.02 14.9 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 FTR, proximal lobe Sec16_C PF12931.7 GAP92366.1 - 7e-09 35.8 0.0 5.2e-08 32.9 0.0 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 GAP92366.1 - 8.9e-07 28.8 0.0 8.9e-07 28.8 0.0 3.5 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 GAP92366.1 - 4.2e-06 27.4 4.9 0.009 16.8 0.1 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat PALB2_WD40 PF16756.5 GAP92366.1 - 0.02 13.8 0.2 0.25 10.2 0.0 2.2 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Sec16 PF12932.7 GAP92366.1 - 0.095 13.3 0.0 0.37 11.4 0.0 2.1 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region RRM_1 PF00076.22 GAP92367.1 - 8e-16 57.6 0.0 1.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAP92367.1 - 0.0031 17.5 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 GAP92367.1 - 0.021 14.9 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif COX6B PF02297.17 GAP92368.1 - 1.8e-18 66.5 4.7 2.2e-18 66.2 4.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 GAP92368.1 - 0.016 15.2 2.2 0.027 14.5 2.0 1.4 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 GAP92368.1 - 0.1 12.5 1.9 0.14 12.1 1.6 1.6 1 1 0 1 1 1 0 APOBEC-like C-terminal domain L51_S25_CI-B8 PF05047.16 GAP92369.1 - 7.7e-19 67.4 0.1 1.3e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain C2 PF00168.30 GAP92370.1 - 1.3e-30 105.7 0.0 4e-17 62.4 0.0 2.6 2 0 0 2 2 2 2 C2 domain JAKMIP_CC3 PF16034.5 GAP92371.1 - 0.57 10.1 4.1 0.78 9.7 2.8 1.8 1 1 1 2 2 2 0 JAKMIP CC3 domain IMS PF00817.20 GAP92372.1 - 1.3e-34 119.3 0.0 2.3e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 GAP92372.1 - 3.6e-16 59.9 0.0 7.5e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 GAP92372.1 - 0.0058 16.9 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.6 GAP92372.1 - 0.059 14.0 0.0 1.2 9.8 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain Mucin PF01456.17 GAP92372.1 - 0.26 11.3 10.5 0.64 10.0 10.5 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein CAP_N PF01213.19 GAP92372.1 - 1.7 8.1 3.9 3.1 7.2 3.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 GAP92372.1 - 3.4 7.7 8.4 6.7 6.8 8.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 HLH PF00010.26 GAP92373.1 - 5.7e-07 29.4 0.0 2e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Presenilin PF01080.17 GAP92373.1 - 2.7 6.6 3.9 3.9 6.1 3.9 1.4 1 0 0 1 1 1 0 Presenilin Amidoligase_2 PF12224.8 GAP92374.1 - 1.9e-17 63.8 0.2 5.9e-12 45.8 0.1 3.2 3 0 0 3 3 3 2 Putative amidoligase enzyme UPF0121 PF03661.13 GAP92375.1 - 5.8e-28 97.9 0.7 7.2e-28 97.6 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Abhydrolase_3 PF07859.13 GAP92376.1 - 1e-31 110.4 0.0 1.4e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAP92376.1 - 3.5e-07 29.5 0.0 5.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 GAP92376.1 - 0.054 13.0 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 GAP92376.1 - 0.11 11.8 0.0 0.69 9.1 0.0 2.1 1 1 0 2 2 2 0 Serine aminopeptidase, S33 BRE PF06113.12 GAP92376.1 - 0.24 10.2 0.0 0.4 9.5 0.0 1.3 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) SBF PF01758.16 GAP92378.1 - 6.6e-52 176.0 10.1 6.6e-52 176.0 10.1 2.1 3 0 0 3 3 3 1 Sodium Bile acid symporter family Kinocilin PF15033.6 GAP92378.1 - 0.23 11.1 0.9 0.6 9.8 0.9 1.7 1 0 0 1 1 1 0 Kinocilin protein Anoctamin PF04547.12 GAP92378.1 - 4 6.2 7.8 0.67 8.7 3.9 1.6 2 0 0 2 2 2 0 Calcium-activated chloride channel Med3 PF11593.8 GAP92379.1 - 4.6 6.3 6.8 5.4 6.1 6.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cyclin_N PF00134.23 GAP92380.1 - 3.8e-08 33.1 0.0 7.3e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Palm_thioest PF02089.15 GAP92381.1 - 2.9e-81 272.9 0.0 3.4e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 GAP92381.1 - 0.011 15.3 0.0 0.34 10.4 0.0 2.1 1 1 0 1 1 1 0 Lipase (class 2) DUF915 PF06028.11 GAP92381.1 - 0.041 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_L1 PF00687.21 GAP92382.1 - 1.4e-52 178.4 0.4 1.4e-52 178.4 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family hNIFK_binding PF12196.8 GAP92382.1 - 0.99 9.0 4.0 1.4 8.4 2.2 2.3 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK ASCH PF04266.14 GAP92383.1 - 0.071 13.7 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 ASCH domain Beta-lactamase PF00144.24 GAP92384.1 - 2.7e-35 122.2 0.0 4.1e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase AAA PF00004.29 GAP92385.1 - 4.2e-18 66.1 0.0 9.2e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP92385.1 - 0.0011 19.4 0.1 0.0011 19.4 0.1 2.7 2 2 0 2 2 2 1 AAA ATPase domain Zot PF05707.12 GAP92385.1 - 0.0033 17.1 0.3 0.075 12.7 0.0 2.8 3 1 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 GAP92385.1 - 0.0042 17.4 0.8 0.024 14.9 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 GAP92385.1 - 0.009 16.0 0.0 0.12 12.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MeaB PF03308.16 GAP92385.1 - 0.021 13.8 0.7 0.089 11.8 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 GAP92385.1 - 0.045 13.9 0.0 0.17 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 GAP92385.1 - 0.072 13.5 3.3 1.5 9.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 GAP92385.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RRN3 PF05327.11 GAP92385.1 - 0.27 9.7 9.6 0.44 9.0 9.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RINGv PF12906.7 GAP92386.1 - 0.00083 19.4 5.5 0.0014 18.7 5.5 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 GAP92386.1 - 0.012 15.7 3.2 0.023 14.9 3.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 GAP92386.1 - 0.039 14.3 5.8 0.066 13.5 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 GAP92386.1 - 0.067 13.0 1.1 0.16 11.8 1.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Peptidase_M28 PF04389.17 GAP92387.1 - 4.1e-39 134.3 0.0 7e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 GAP92387.1 - 1e-10 41.5 0.2 2.3e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 GAP92387.1 - 0.0001 22.1 0.0 0.00023 20.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cyclin_N PF00134.23 GAP92388.1 - 6.9e-46 155.1 0.0 1.2e-44 151.2 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 GAP92388.1 - 3.5e-35 120.7 0.0 6.5e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HABP4_PAI-RBP1 PF04774.15 GAP92388.1 - 0.33 11.8 6.9 0.89 10.4 6.9 1.7 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Ribosomal_L2_C PF03947.18 GAP92389.1 - 9.9e-50 168.0 2.5 2.3e-49 166.8 2.5 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 GAP92389.1 - 2.1e-25 88.5 0.4 2.1e-25 88.5 0.4 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.16 GAP92390.1 - 2.4e-18 66.2 56.3 1.2e-12 47.4 30.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Spt20 PF12090.8 GAP92390.1 - 2.9 7.4 6.2 4.7 6.7 6.2 1.2 1 0 0 1 1 1 0 Spt20 family Ligase_CoA PF00549.19 GAP92391.1 - 5.5e-33 113.9 0.8 2e-17 63.4 0.1 2.6 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 GAP92391.1 - 1.9e-16 60.5 0.3 6.4e-16 58.8 0.3 1.9 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 GAP92391.1 - 5e-08 32.8 0.0 1.3e-05 25.1 0.0 2.7 3 0 0 3 3 3 2 Succinyl-CoA ligase like flavodoxin domain CHCH PF06747.13 GAP92392.1 - 4.7e-05 23.4 0.6 6.8e-05 22.9 0.6 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 GAP92392.1 - 0.022 15.1 2.9 0.11 12.8 3.0 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 GAP92392.1 - 0.072 13.5 3.4 2.7 8.4 0.3 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 GAP92392.1 - 0.3 11.4 1.8 13 6.1 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) CxC7 PF18866.1 GAP92393.1 - 0.022 14.9 1.3 0.046 13.9 0.1 2.0 2 0 0 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases NPR3 PF03666.13 GAP92394.1 - 9.1e-142 473.1 12.3 6.2e-141 470.4 0.0 2.1 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 RRN3 PF05327.11 GAP92394.1 - 0.0021 16.7 0.5 0.0033 16.1 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 GAP92394.1 - 0.0025 16.2 4.5 0.0041 15.5 4.5 1.2 1 0 0 1 1 1 1 CDC45-like protein PNISR PF15996.5 GAP92394.1 - 0.0039 17.5 9.3 0.0088 16.3 9.3 1.5 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR NPR2 PF06218.11 GAP92394.1 - 0.084 11.6 0.2 0.15 10.8 0.2 1.3 1 0 0 1 1 1 0 Nitrogen permease regulator 2 DUF2828 PF11443.8 GAP92394.1 - 0.17 9.9 7.4 0.27 9.3 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Rtf2 PF04641.12 GAP92394.1 - 0.18 11.1 6.9 0.37 10.1 6.9 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger EOS1 PF12326.8 GAP92394.1 - 0.81 9.6 2.5 2 8.3 2.5 1.6 1 0 0 1 1 1 0 N-glycosylation protein CPSF100_C PF13299.6 GAP92394.1 - 1.1 9.4 5.5 2.9 8.1 5.5 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CLN3 PF02487.17 GAP92394.1 - 1.7 7.6 3.4 2.7 6.9 3.4 1.2 1 0 0 1 1 1 0 CLN3 protein Connexin PF00029.19 GAP92394.1 - 1.8 8.3 7.7 3.7 7.2 7.7 1.4 1 0 0 1 1 1 0 Connexin Zip PF02535.22 GAP92394.1 - 3.3 6.8 4.2 5.4 6.1 4.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 GAP92394.1 - 4.8 6.5 11.1 8.3 5.7 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4834 PF16118.5 GAP92394.1 - 5.1 8.1 7.6 13 6.8 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 GAP92394.1 - 8.2 5.1 11.7 13 4.4 11.7 1.2 1 0 0 1 1 1 0 Presenilin HLH PF00010.26 GAP92395.1 - 1.3e-11 44.3 0.0 4.7e-11 42.5 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.12 GAP92396.1 - 3e-34 117.8 14.7 4.4e-34 117.3 14.7 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family La PF05383.17 GAP92397.1 - 3.2e-17 62.3 0.1 6.1e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 La domain HAT PF02184.16 GAP92399.1 - 3.3e-22 78.1 77.9 1.5e-12 47.2 3.6 14.1 15 0 0 15 15 15 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 GAP92399.1 - 6.2e-20 70.2 30.0 0.0027 18.4 0.3 11.3 9 3 4 13 13 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 GAP92399.1 - 4.3e-19 68.8 0.3 7.5e-05 23.2 0.0 6.1 5 1 2 7 7 7 4 Tetratricopeptide repeat Suf PF05843.14 GAP92399.1 - 3.8e-15 56.6 23.9 0.0016 18.5 1.9 6.5 4 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 GAP92399.1 - 4.9e-09 35.9 3.4 0.0028 17.9 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAP92399.1 - 2.3e-07 30.5 6.2 2.9 8.3 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 GAP92399.1 - 6.2e-07 29.0 17.2 2 8.7 0.1 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_15 PF13429.6 GAP92399.1 - 1.3e-06 27.8 13.6 0.79 8.9 0.2 6.2 2 1 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAP92399.1 - 0.00035 21.1 14.6 3.8 8.2 0.0 7.4 8 1 2 10 10 10 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP92399.1 - 0.021 14.7 3.8 63 3.6 0.5 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 GAP92399.1 - 0.027 14.6 6.1 9.8 6.4 0.0 5.5 4 1 0 5 5 5 0 Tetratricopeptide repeat ECSIT PF06239.11 GAP92399.1 - 0.12 11.5 0.1 0.12 11.5 0.1 2.7 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway Fis1_TPR_C PF14853.6 GAP92399.1 - 1.2 9.2 9.0 17 5.5 0.3 5.3 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 GAP92399.1 - 3 8.2 22.7 4.3 7.7 0.0 7.6 11 0 0 11 11 8 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 GAP92399.1 - 4 7.4 24.1 11 6.0 0.0 7.1 6 1 3 9 9 9 0 Mad3/BUB1 homology region 1 Nop PF01798.18 GAP92400.1 - 5.3e-74 248.5 0.0 8.1e-74 248.0 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 GAP92400.1 - 6.5e-47 159.4 2.2 1.2e-46 158.5 1.6 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain zf-C2H2 PF00096.26 GAP92402.1 - 6.9e-05 23.1 12.1 0.0024 18.2 1.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP92402.1 - 0.0083 16.5 2.7 0.0083 16.5 2.7 2.8 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 GAP92402.1 - 0.022 15.4 2.3 0.037 14.6 0.3 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 GAP92402.1 - 0.024 15.4 10.3 0.17 12.8 1.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Integrin_B_tail PF07965.12 GAP92402.1 - 0.032 14.7 1.0 0.062 13.8 0.6 1.6 1 1 1 2 2 2 0 Integrin beta tail domain zf-met PF12874.7 GAP92402.1 - 0.34 11.4 7.6 0.92 10.0 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Macoilin PF09726.9 GAP92402.1 - 4.6 5.7 9.8 5.9 5.3 9.8 1.1 1 0 0 1 1 1 0 Macoilin family adh_short_C2 PF13561.6 GAP92403.1 - 1.5e-56 191.6 2.7 1.1e-41 143.0 1.3 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP92403.1 - 8.6e-42 142.8 1.3 1.1e-41 142.5 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase SWIRM-assoc_3 PF16498.5 GAP92403.1 - 0.033 14.4 0.9 0.11 12.7 0.9 1.9 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal GST_N_3 PF13417.6 GAP92404.1 - 2.1e-18 66.5 0.0 5.4e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAP92404.1 - 2.7e-14 53.2 0.1 8.4e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAP92404.1 - 1.6e-08 34.8 0.0 2.2e-07 31.1 0.0 2.8 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP92404.1 - 2.2e-05 24.4 0.3 6.6e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAP92404.1 - 0.0023 18.1 0.1 0.059 13.6 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAP92404.1 - 0.0062 17.1 0.0 0.016 15.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 GAP92404.1 - 0.08 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF5053 PF16476.5 GAP92404.1 - 0.081 12.6 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) Fungal_trans PF04082.18 GAP92405.1 - 8.2e-20 70.9 0.0 1.4e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP92405.1 - 6.7e-10 38.9 9.5 1.4e-09 37.9 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 GAP92406.1 - 9.4e-24 83.2 0.3 4.3e-06 27.3 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP92406.1 - 6.2e-15 55.3 0.0 0.00041 20.6 0.0 5.3 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP92406.1 - 1e-06 27.7 0.2 0.0028 16.4 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 GAP92406.1 - 2e-05 24.6 0.4 0.0011 18.9 0.1 3.0 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 GAP92406.1 - 7.4e-05 21.9 0.0 0.93 8.4 0.0 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 GAP92406.1 - 0.016 13.7 0.0 2.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Arena_nucleocap PF00843.17 GAP92406.1 - 0.043 12.7 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain Coatomer_WDAD PF04053.14 GAP92406.1 - 0.17 10.9 0.0 1.6 7.7 0.0 1.9 1 1 0 1 1 1 0 Coatomer WD associated region Phage_term_sma PF07141.11 GAP92406.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit RIC1 PF07064.13 GAP92407.1 - 1.4e-95 319.5 0.0 1.9e-95 319.1 0.0 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 GAP92407.1 - 0.17 12.2 0.0 14 6.1 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CK_II_beta PF01214.18 GAP92408.1 - 1.7e-76 256.1 0.4 2.1e-76 255.8 0.4 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PAP2 PF01569.21 GAP92409.1 - 7e-23 80.9 6.3 6e-22 77.9 4.4 3.0 2 1 0 2 2 2 1 PAP2 superfamily NCE101 PF11654.8 GAP92409.1 - 0.53 10.0 1.9 30 4.4 0.1 2.6 2 0 0 2 2 2 0 Non-classical export protein 1 LIM PF00412.22 GAP92410.1 - 4.5e-14 52.4 13.8 4e-07 30.2 0.4 3.8 2 1 1 3 3 3 2 LIM domain Churchill PF06573.11 GAP92410.1 - 0.084 13.2 1.9 5.6 7.3 0.2 3.1 3 0 0 3 3 3 0 Churchill protein Nudix_N_2 PF14803.6 GAP92410.1 - 7 6.7 15.9 15 5.6 0.0 5.4 5 1 0 5 5 5 0 Nudix N-terminal Rad60-SLD PF11976.8 GAP92411.1 - 4.6e-19 68.0 0.5 5.5e-19 67.8 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 GAP92411.1 - 1.3e-11 44.0 0.4 1.5e-11 43.8 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Phage_Coat_B PF05356.11 GAP92412.1 - 0.1 12.5 1.1 6.4 6.8 0.2 2.7 2 0 0 2 2 2 0 Phage Coat protein B PIP5K PF01504.18 GAP92413.1 - 1.4e-101 339.3 0.0 2.9e-101 338.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase COX6B PF02297.17 GAP92414.1 - 1.4e-22 79.7 8.1 1.9e-22 79.3 8.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.11 GAP92414.1 - 0.0017 18.5 0.4 0.0022 18.1 0.4 1.1 1 0 0 1 1 1 1 Prolamin-like Pet191_N PF10203.9 GAP92414.1 - 0.015 15.5 3.3 0.053 13.8 3.3 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF2664 PF10867.8 GAP92414.1 - 0.17 12.3 1.5 0.38 11.2 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2664) SYS1 PF09801.9 GAP92415.1 - 7.6e-36 123.4 4.2 1.2e-35 122.8 4.2 1.3 1 1 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network PHO4 PF01384.20 GAP92415.1 - 0.0037 16.4 1.1 0.0049 16.0 1.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family Acyl-CoA_dh_N PF02771.16 GAP92417.1 - 3e-24 85.9 0.4 6.5e-24 84.8 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 GAP92417.1 - 8.7e-23 81.2 0.1 1.5e-22 80.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAP92417.1 - 1.9e-17 63.3 0.0 3.6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAP92417.1 - 2.6e-05 24.5 0.1 4.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 GAP92418.1 - 4e-52 175.6 0.0 4.4e-52 175.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAP92418.1 - 0.0047 16.6 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 GAP92418.1 - 0.036 14.3 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 GAP92418.1 - 0.045 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.12 GAP92419.1 - 9.3e-32 110.3 0.0 1.8e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAP92419.1 - 2.9e-20 72.4 0.2 1.1e-19 70.6 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 GAP92419.1 - 9.3e-18 64.5 11.8 9.3e-18 64.5 11.8 2.5 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAA_hydrolase PF01557.18 GAP92420.1 - 4.7e-29 101.6 0.0 6.3e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Hydrophobin_2 PF06766.11 GAP92420.1 - 3.3e-28 97.4 7.2 4.8e-28 96.9 7.2 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Glyoxalase PF00903.25 GAP92421.1 - 9.9e-08 32.2 5.4 0.00018 21.7 3.9 3.0 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RPA43_OB PF17875.1 GAP92421.1 - 0.12 12.9 0.9 0.23 12.1 0.3 1.7 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Fungal_trans PF04082.18 GAP92422.1 - 1.2e-19 70.5 0.0 1.7e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAP92422.1 - 2.7e-09 37.0 12.8 9e-05 22.7 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP92422.1 - 5.8e-07 29.6 2.8 5.8e-07 29.6 2.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP92422.1 - 5.6e-06 26.7 11.2 0.0029 18.3 0.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 GAP92422.1 - 1.5e-05 24.6 9.4 0.012 15.3 1.4 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 GAP92422.1 - 1.6 8.9 12.5 0.11 12.5 1.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 GAP92422.1 - 3.9 7.2 6.5 10 5.8 0.2 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain adh_short_C2 PF13561.6 GAP92423.1 - 1.3e-63 214.7 0.4 1.5e-63 214.5 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP92423.1 - 2.6e-40 138.0 0.2 3.4e-40 137.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 GAP92423.1 - 4.9e-13 49.4 0.2 6.9e-13 48.9 0.2 1.2 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 GAP92424.1 - 1.2e-34 119.8 26.9 4e-34 118.1 27.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily XPG_I PF00867.18 GAP92425.1 - 1.4e-30 105.5 0.0 1.4e-30 105.5 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 GAP92425.1 - 4.8e-19 68.7 0.0 1.5e-18 67.1 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 GAP92425.1 - 9.4e-05 22.9 2.0 0.00017 22.1 0.0 2.3 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 GAP92425.1 - 0.041 14.5 0.0 0.092 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Myticin-prepro PF10690.9 GAP92427.1 - 1 9.7 7.7 1.8 8.9 7.7 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Amidoligase_2 PF12224.8 GAP92428.1 - 8.4e-15 55.1 0.0 8.6e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme Fungal_trans_2 PF11951.8 GAP92431.1 - 1.6e-15 56.9 0.3 5.4e-14 51.8 0.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP92431.1 - 0.00028 21.0 6.4 0.00052 20.1 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 GAP92432.1 - 1.3e-13 50.6 0.0 2.3e-12 46.5 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 GAP92432.1 - 0.0073 16.4 0.0 0.036 14.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif Pex14_N PF04695.13 GAP92432.1 - 0.4 11.3 3.3 0.98 10.1 3.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.32 GAP92433.1 - 2e-08 34.7 0.1 0.01 16.6 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP92433.1 - 1.3e-05 25.4 0.0 0.052 13.8 0.0 3.6 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 GAP92433.1 - 5.7e-05 22.6 0.0 0.00013 21.4 0.0 1.6 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 GAP92433.1 - 0.0048 15.0 0.0 0.011 13.7 0.0 1.5 1 1 1 2 2 2 1 IKI3 family Ge1_WD40 PF16529.5 GAP92433.1 - 0.12 11.3 0.0 7.1 5.5 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2415 PF10313.9 GAP92433.1 - 0.14 12.1 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Septin PF00735.18 GAP92434.1 - 4.6e-108 360.8 0.1 9.4e-108 359.7 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 GAP92434.1 - 0.00016 21.8 0.0 0.00037 20.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAP92434.1 - 0.011 15.3 0.1 0.067 12.7 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAP92434.1 - 0.012 15.6 0.7 0.012 15.6 0.7 2.2 2 1 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 GAP92434.1 - 0.018 15.6 1.8 8.1 6.9 2.3 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 GAP92434.1 - 0.032 14.3 3.8 2.2 8.3 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AAA_22 PF13401.6 GAP92434.1 - 0.049 13.9 1.0 0.093 13.0 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 GAP92434.1 - 0.049 13.8 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 GAP92434.1 - 0.098 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) EB1 PF03271.17 GAP92434.1 - 0.1 12.8 0.8 2.1 8.6 1.6 2.5 2 0 0 2 2 2 0 EB1-like C-terminal motif FtsK_SpoIIIE PF01580.18 GAP92434.1 - 0.11 11.8 0.1 0.11 11.8 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 GAP92434.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ribosomal_S17e PF00833.18 GAP92434.1 - 0.87 9.5 3.9 2.3 8.2 3.9 1.7 1 0 0 1 1 1 0 Ribosomal S17 Bax1-I PF01027.20 GAP92435.1 - 1.8e-53 181.5 22.2 2.1e-53 181.2 22.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SfLAP PF11139.8 GAP92435.1 - 0.072 12.5 4.8 0.082 12.3 0.1 2.8 2 2 1 3 3 3 0 Sap, sulfolipid-1-addressing protein 7TMR-DISM_7TM PF07695.11 GAP92435.1 - 3.7 7.4 24.8 23 4.8 12.6 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling TRAM_LAG1_CLN8 PF03798.16 GAP92436.1 - 3.7e-48 163.9 22.6 3.7e-48 163.9 22.6 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 GAP92436.1 - 2.9e-19 68.5 0.2 2.9e-19 68.5 0.2 2.4 2 0 0 2 2 2 1 TRAM1-like protein SMBP PF16785.5 GAP92437.1 - 0.055 13.7 2.7 0.083 13.1 2.7 1.3 1 0 0 1 1 1 0 Small metal-binding protein Glyco_transf_25 PF01755.17 GAP92439.1 - 5.2e-05 23.2 0.0 0.00039 20.4 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) NOA36 PF06524.12 GAP92439.1 - 0.73 9.1 2.1 1.1 8.6 2.1 1.2 1 0 0 1 1 1 0 NOA36 protein ABC_tran PF00005.27 GAP92440.1 - 9.5e-49 165.4 0.1 4.7e-26 91.9 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 GAP92440.1 - 5.9e-15 55.9 3.9 0.00058 19.8 0.5 4.6 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAP92440.1 - 7.7e-12 45.1 0.3 0.0051 16.3 0.0 4.3 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAP92440.1 - 4.2e-09 37.2 0.4 0.00073 20.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 GAP92440.1 - 7.9e-07 29.2 0.0 0.011 15.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP92440.1 - 1e-06 28.8 0.1 0.0097 15.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 GAP92440.1 - 1.8e-06 27.6 0.5 0.023 14.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.24 GAP92440.1 - 8e-05 22.5 3.3 0.00011 22.0 1.8 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.6 GAP92440.1 - 0.00065 20.0 0.3 1.9 8.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 GAP92440.1 - 0.0022 18.2 0.0 1.6 9.0 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 GAP92440.1 - 0.0025 18.4 0.0 0.75 10.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAP92440.1 - 0.0038 17.4 0.0 3.1 7.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 GAP92440.1 - 0.0042 17.2 0.9 0.9 9.6 0.1 3.4 3 0 0 3 3 3 1 Helicase HerA, central domain RNA_helicase PF00910.22 GAP92440.1 - 0.0045 17.4 0.1 3.7 8.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.23 GAP92440.1 - 0.0045 17.1 0.5 0.43 10.6 0.0 3.0 3 1 0 3 3 2 1 Dynamin family NACHT PF05729.12 GAP92440.1 - 0.0047 16.9 0.1 2.2 8.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 GAP92440.1 - 0.0054 15.8 0.5 1.2 8.1 0.1 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 GAP92440.1 - 0.0055 16.5 3.4 0.37 10.4 0.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 GAP92440.1 - 0.0065 16.7 0.0 0.23 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 GAP92440.1 - 0.016 14.9 0.0 0.82 9.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 GAP92440.1 - 0.016 15.6 0.0 5.2 7.5 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 GAP92440.1 - 0.023 14.4 1.0 2.9 7.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAP92440.1 - 0.023 14.4 0.6 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 GAP92440.1 - 0.035 13.7 0.6 9 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 GAP92440.1 - 0.056 13.8 0.0 3.8 7.9 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 GAP92440.1 - 0.064 11.9 0.0 3.7 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 GAP92440.1 - 0.1 11.7 0.1 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) HEAT PF02985.22 GAP92440.1 - 0.33 11.3 2.2 2.7e+02 2.3 0.0 5.1 6 0 0 6 6 5 0 HEAT repeat HEAT_2 PF13646.6 GAP92440.1 - 0.42 11.0 2.5 8.9 6.8 0.0 3.8 3 1 0 4 4 3 0 HEAT repeats ANAPC5 PF12862.7 GAP92441.1 - 3.7e-34 116.7 5.2 3.7e-34 116.7 5.2 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 GAP92441.1 - 0.00065 19.9 7.4 1.2 9.5 0.0 5.5 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 GAP92441.1 - 0.0024 17.8 0.6 1.5 9.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP92441.1 - 0.0037 17.0 1.3 15 5.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAP92441.1 - 0.021 14.7 1.4 11 6.1 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 GAP92441.1 - 0.2 12.5 11.6 5.7 8.0 0.0 6.1 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 GAP92441.1 - 0.69 10.5 13.5 19 5.8 0.1 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat CIA30 PF08547.12 GAP92442.1 - 1.3e-46 158.6 0.0 1.6e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) ANTH PF07651.16 GAP92443.1 - 8.6e-80 267.7 0.0 8.6e-80 267.7 0.0 2.6 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 GAP92443.1 - 7.8e-56 188.6 8.7 7.8e-56 188.6 8.7 6.1 3 2 3 6 6 6 2 I/LWEQ domain TcdB_N PF12918.7 GAP92443.1 - 0.085 13.2 2.6 1.8 8.9 0.2 3.9 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Surfac_D-trimer PF09006.11 GAP92443.1 - 0.83 9.6 5.1 0.67 9.9 1.5 2.8 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation T2SSF PF00482.23 GAP92443.1 - 6.4 6.8 6.5 5.1 7.1 1.0 3.5 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F COX6A PF02046.15 GAP92444.1 - 1.2e-53 180.3 1.3 1.4e-53 180.1 1.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos PF03372.23 GAP92445.1 - 5.7e-14 52.2 0.1 8.7e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 GAP92445.1 - 2.5e-07 30.7 1.8 6.8e-07 29.3 1.8 1.8 1 1 0 1 1 1 1 GRF zinc finger IcmF_C PF06744.12 GAP92445.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal MFS_1 PF07690.16 GAP92446.1 - 1.6e-31 109.5 38.1 1.6e-31 109.5 38.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP92446.1 - 2.5e-08 33.3 5.6 2.5e-08 33.3 5.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Peroxidase_2 PF01328.17 GAP92448.1 - 2e-47 162.2 0.1 2.5e-47 161.8 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Collar PF07484.12 GAP92448.1 - 0.025 14.6 0.0 8.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Phage Tail Collar Domain MFS_1 PF07690.16 GAP92449.1 - 2.6e-37 128.6 20.9 2.6e-37 128.6 20.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP92449.1 - 1.6e-07 30.6 2.5 1.6e-07 30.6 2.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAP92449.1 - 0.00075 18.5 0.0 0.0035 16.3 0.0 2.2 1 1 0 1 1 1 1 MFS_1 like family TRI12 PF06609.13 GAP92449.1 - 0.002 16.6 1.0 0.0031 16.0 1.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cutinase PF01083.22 GAP92450.1 - 2.1e-20 73.4 0.4 2.4e-20 73.2 0.4 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAP92450.1 - 0.0027 17.3 0.1 0.0038 16.8 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.20 GAP92450.1 - 0.016 15.3 0.0 0.022 14.9 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain CPCFC PF17223.3 GAP92450.1 - 4.8 7.0 5.0 71 3.3 0.1 3.4 3 0 0 3 3 3 0 Cuticle protein CPCFC Zn_clus PF00172.18 GAP92451.1 - 5e-11 42.5 11.2 1e-10 41.5 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAP92451.1 - 0.00034 19.6 3.1 0.00052 18.9 3.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain HBM PF16591.5 GAP92451.1 - 0.076 12.4 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain H_lectin PF09458.10 GAP92452.1 - 1.1e-09 38.3 0.0 2.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 H-type lectin domain MMR_HSR1 PF01926.23 GAP92453.1 - 5.3e-09 36.2 0.0 1.3e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 GAP92453.1 - 1.2e-07 31.2 0.1 3.5e-07 29.8 0.0 1.6 1 1 1 2 2 2 1 AIG1 family AAA_22 PF13401.6 GAP92453.1 - 3e-05 24.3 0.0 0.0001 22.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 GAP92453.1 - 9.8e-05 22.5 0.6 0.11 12.6 0.0 3.0 2 1 1 3 3 3 2 Dynamin family Septin PF00735.18 GAP92453.1 - 0.00014 21.2 0.0 0.00031 20.1 0.0 1.6 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 GAP92453.1 - 0.00026 21.0 0.0 0.00058 19.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 GAP92453.1 - 0.0011 19.5 0.0 0.0026 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 GAP92453.1 - 0.01 15.4 0.1 0.026 14.0 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B T2SSE PF00437.20 GAP92453.1 - 0.01 14.9 0.2 0.025 13.6 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 GAP92453.1 - 0.011 15.1 0.6 0.049 13.0 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_28 PF13521.6 GAP92453.1 - 0.016 15.5 2.0 0.12 12.6 0.1 3.1 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.6 GAP92453.1 - 0.019 15.4 0.0 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 GAP92453.1 - 0.023 14.5 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 GAP92453.1 - 0.042 13.6 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 GAP92453.1 - 0.048 13.1 0.2 0.22 10.9 0.0 2.1 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 GAP92453.1 - 0.053 14.0 0.0 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Spore_IV_A PF09547.10 GAP92453.1 - 0.055 12.4 0.1 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) GTP_EFTU PF00009.27 GAP92453.1 - 0.067 12.7 0.8 1.4 8.4 0.8 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 GAP92453.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 GAP92453.1 - 0.088 12.1 1.2 7.9 5.7 0.4 2.3 2 0 0 2 2 2 0 KaiC DUF87 PF01935.17 GAP92453.1 - 0.21 11.7 0.7 3.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 GAP92453.1 - 0.21 11.3 2.6 3.1 7.5 0.2 2.9 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein RicinB_lectin_2 PF14200.6 GAP92455.1 - 8e-11 42.5 14.3 8.6e-08 32.8 4.5 2.9 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like SPX PF03105.19 GAP92456.1 - 1.1 9.1 4.6 1.7 8.5 4.6 1.3 1 0 0 1 1 1 0 SPX domain ETF_QO PF05187.13 GAP92457.1 - 2.6e-47 159.3 0.2 4.1e-47 158.6 0.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 GAP92457.1 - 8.3e-08 32.2 0.2 0.00012 21.8 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP92457.1 - 8.6e-08 32.3 0.0 2.8e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP92457.1 - 3.3e-05 23.3 0.0 9.5e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP92457.1 - 7.6e-05 22.0 0.3 0.005 16.0 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 GAP92457.1 - 0.00013 20.9 0.2 0.00019 20.3 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 GAP92457.1 - 0.00039 19.4 0.0 0.2 10.5 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 GAP92457.1 - 0.00066 20.2 0.1 0.9 10.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP92457.1 - 0.0008 18.7 0.0 0.0071 15.6 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 GAP92457.1 - 0.00096 18.5 0.2 0.002 17.4 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 GAP92457.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAP92457.1 - 0.0013 18.7 0.1 0.0072 16.3 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAP92457.1 - 0.005 16.1 0.3 0.0071 15.6 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 GAP92457.1 - 0.019 15.5 0.6 0.057 14.0 0.6 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 GAP92457.1 - 0.043 12.9 0.2 0.063 12.3 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Internalin_N PF12354.8 GAP92457.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal GIDA PF01134.22 GAP92457.1 - 0.089 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 GAP92457.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_2 PF12797.7 GAP92457.1 - 0.12 12.5 0.6 0.33 11.1 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain AMP-binding PF00501.28 GAP92459.1 - 1.7e-74 250.9 0.1 5.2e-74 249.3 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAP92459.1 - 3.1e-56 190.4 0.3 6.8e-56 189.3 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 GAP92459.1 - 8.8e-53 178.7 2.1 1.8e-52 177.6 2.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP92459.1 - 1.2e-40 139.6 3.7 2.5e-40 138.5 3.7 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP92459.1 - 6.2e-22 78.4 3.6 9.4e-18 64.7 1.7 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 GAP92459.1 - 1.8e-17 63.7 0.8 4.6e-09 36.1 0.0 3.2 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAP92459.1 - 6.4e-10 39.2 0.0 2.5e-09 37.3 0.0 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 GAP92459.1 - 1e-07 31.4 2.4 0.00092 18.4 0.0 3.0 2 1 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 GAP92459.1 - 1.2e-06 27.9 4.1 0.00034 19.8 0.1 3.3 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 GAP92459.1 - 1.3e-06 28.4 2.8 1.3e-06 28.4 2.8 2.5 3 0 0 3 3 3 1 NAD(P)H-binding 3Beta_HSD PF01073.19 GAP92459.1 - 5.6e-06 25.6 0.2 0.0025 16.9 0.0 2.9 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 GAP92459.1 - 0.00034 20.0 0.1 0.00087 18.6 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 GAP92459.1 - 0.00083 18.8 0.1 0.32 10.3 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase DFP PF04127.15 GAP92459.1 - 0.0055 16.6 3.7 0.0081 16.0 2.2 1.9 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 GAP92459.1 - 0.011 15.3 2.9 0.69 9.4 1.1 2.6 2 0 0 2 2 2 0 NmrA-like family ApbA PF02558.16 GAP92459.1 - 0.018 14.7 1.5 0.038 13.6 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 GAP92459.1 - 0.071 13.7 1.1 1.6 9.4 0.2 2.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 GAP92459.1 - 0.096 11.9 0.2 0.18 11.0 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 GAP92459.1 - 0.11 12.4 0.5 0.24 11.3 0.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TBP PF00352.21 GAP92460.1 - 1.3e-67 223.7 0.1 6.9e-33 112.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 GAP92460.1 - 0.0001 22.3 0.0 0.22 11.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 GAP92460.1 - 0.12 12.2 0.1 0.66 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DAO PF01266.24 GAP92461.1 - 2.1e-38 132.8 2.5 3e-38 132.3 2.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAP92461.1 - 1.3e-05 25.2 0.1 0.036 14.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 GAP92461.1 - 0.00024 20.4 0.0 1.3 8.2 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP92461.1 - 0.0013 18.9 1.0 0.0027 17.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 GAP92461.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PMR5N PF14416.6 GAP92461.1 - 0.12 12.7 1.7 10 6.5 0.1 2.5 2 0 0 2 2 2 0 PMR5 N terminal Domain Dicty_REP PF05086.12 GAP92461.1 - 0.29 9.1 1.7 0.51 8.2 1.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Surp PF01805.20 GAP92462.1 - 1.2e-10 41.3 0.0 2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Surp module Clr5 PF14420.6 GAP92465.1 - 8.8e-05 22.6 2.3 0.00018 21.7 2.3 1.5 1 0 0 1 1 1 1 Clr5 domain DAO PF01266.24 GAP92466.1 - 2.3e-54 185.3 5.8 4e-42 145.1 4.8 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP92466.1 - 5.6e-08 32.4 0.0 0.0082 15.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP92466.1 - 3.7e-07 30.6 0.0 0.019 15.5 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP92466.1 - 6.4e-06 26.3 0.1 1.8e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 GAP92466.1 - 0.00013 20.9 0.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 GAP92466.1 - 0.00028 20.9 0.5 0.058 13.4 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 GAP92466.1 - 0.00094 18.6 0.0 0.003 16.9 0.1 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GMC_oxred_N PF00732.19 GAP92466.1 - 0.0052 16.2 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase Sacchrp_dh_NADP PF03435.18 GAP92466.1 - 0.0055 17.0 0.0 0.026 14.8 0.0 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_oxidored PF12831.7 GAP92466.1 - 0.014 14.8 0.0 0.066 12.6 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase MCRA PF06100.11 GAP92466.1 - 0.032 13.0 0.0 0.17 10.7 0.0 1.8 2 0 0 2 2 2 0 MCRA family Thi4 PF01946.17 GAP92466.1 - 0.039 13.2 0.0 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 GAP92466.1 - 0.19 10.7 0.1 0.83 8.6 0.1 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein PhyH PF05721.13 GAP92468.1 - 0.0023 18.2 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pectate_lyase_3 PF12708.7 GAP92470.1 - 4.2e-99 330.7 20.4 2.8e-85 285.5 5.8 3.5 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAP92470.1 - 3.4e-09 36.3 2.4 0.00092 18.9 0.3 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Fungal_trans PF04082.18 GAP92471.1 - 1.6e-13 50.3 1.4 3.1e-13 49.4 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 GAP92471.1 - 2e-07 31.1 7.7 0.0079 16.6 0.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP92471.1 - 4.9e-05 23.8 7.6 0.027 15.3 2.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAP92471.1 - 0.00011 22.5 14.0 0.00045 20.5 1.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAP92471.1 - 0.033 14.5 0.3 0.33 11.3 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF2461 PF09365.10 GAP92472.1 - 8.5e-82 274.1 0.1 1.1e-81 273.8 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) RNA_pol_3_Rpc31 PF11705.8 GAP92472.1 - 0.0064 16.8 15.4 0.0064 16.8 15.4 3.3 3 0 0 3 3 3 2 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 GAP92472.1 - 0.83 9.4 37.6 1.8 8.3 7.6 3.5 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Glyco_hydro_92 PF07971.12 GAP92473.1 - 1.1e-143 479.6 0.0 1.3e-143 479.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 GAP92473.1 - 2.9e-62 210.7 0.3 4.5e-62 210.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_125 PF06824.11 GAP92474.1 - 1.1e-185 617.5 0.0 1.3e-185 617.3 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) ATG13 PF10033.9 GAP92475.1 - 6.7e-71 238.8 0.0 1e-70 238.2 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 VHS PF00790.19 GAP92476.1 - 8.3e-35 119.7 0.0 2e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 GAP92476.1 - 1.6e-16 59.6 0.0 3.7e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 GAP92476.1 - 2.1e-15 56.3 1.3 2.4e-15 56.1 0.2 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 GAP92476.1 - 2.1e-13 49.7 0.0 4.7e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 GAP92476.1 - 2e-10 40.8 2.5 3.6e-10 40.0 1.7 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 GAP92476.1 - 0.013 15.3 3.3 0.034 14.1 3.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Clr5 PF14420.6 GAP92477.1 - 5.7e-21 74.5 0.9 1.7e-20 72.9 0.9 1.9 1 0 0 1 1 1 1 Clr5 domain SNF2_N PF00176.23 GAP92478.1 - 5.4e-66 222.7 1.0 2.8e-61 207.2 0.2 3.1 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP92478.1 - 2.8e-16 59.8 0.0 8.7e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP92478.1 - 1.2e-06 28.7 0.0 3.5e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 GAP92478.1 - 0.067 12.8 0.2 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 DEAD_2 NMO PF03060.15 GAP92479.1 - 2.9e-59 201.1 1.5 5.2e-58 197.0 1.5 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 GAP92479.1 - 8e-15 54.7 0.1 1e-13 51.0 0.1 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 GAP92479.1 - 1e-05 24.7 0.2 1.7e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 GAP92479.1 - 0.016 14.7 0.1 0.046 13.2 0.1 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.17 GAP92479.1 - 0.016 14.4 0.7 0.058 12.5 0.7 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase TMP-TENI PF02581.17 GAP92479.1 - 0.041 13.2 0.2 0.073 12.4 0.2 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase NanE PF04131.14 GAP92479.1 - 0.075 12.2 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF1902 PF08972.11 GAP92479.1 - 0.16 12.0 0.0 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) SelR PF01641.18 GAP92480.1 - 2.7e-48 163.0 0.2 3.5e-48 162.7 0.2 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 GAP92480.1 - 0.034 14.2 0.3 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 GAP92480.1 - 0.047 13.4 0.1 0.8 9.5 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 GAP92480.1 - 0.071 13.3 0.3 0.18 12.0 0.3 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ribosomal_L37e PF01907.19 GAP92480.1 - 0.61 10.3 5.8 11 6.3 1.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L37e zf-C2H2_2 PF12756.7 GAP92481.1 - 2.2e-30 104.9 25.3 6.4e-29 100.3 2.6 3.8 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 GAP92481.1 - 3.6e-09 36.7 14.5 1.3e-05 25.4 1.2 4.0 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 GAP92481.1 - 1e-05 25.7 1.3 1e-05 25.7 1.3 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 GAP92481.1 - 0.0001 22.8 15.3 0.29 12.1 0.2 5.2 4 0 0 4 4 4 2 C2H2-type zinc finger Ribosomal_S5 PF00333.20 GAP92481.1 - 0.0015 18.5 1.9 0.14 12.2 0.1 2.9 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain SnoaL_2 PF12680.7 GAP92481.1 - 0.093 13.4 0.1 2 9.1 0.1 2.5 2 0 0 2 2 2 0 SnoaL-like domain DUF629 PF04780.12 GAP92481.1 - 0.23 9.9 1.9 2.5 6.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 GAP92481.1 - 0.41 11.2 20.1 0.96 10.0 0.4 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type ZZ PF00569.17 GAP92481.1 - 8.5 6.3 8.0 1.6 8.6 0.3 2.8 3 0 0 3 3 3 0 Zinc finger, ZZ type HECT PF00632.25 GAP92482.1 - 6.2e-67 226.2 0.0 1e-66 225.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 GAP92482.1 - 3.6e-18 65.6 2.0 7.6e-18 64.5 2.0 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Cpn60_TCP1 PF00118.24 GAP92483.1 - 8.9e-158 525.9 3.6 1e-157 525.8 3.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AMP-binding PF00501.28 GAP92484.1 - 7.4e-85 285.1 0.0 9.7e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UCH PF00443.29 GAP92485.1 - 3.8e-30 105.3 0.0 5.4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 GAP92485.1 - 1.6e-12 47.7 0.0 2.5e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 GAP92485.1 - 0.00034 21.1 0.0 0.00076 20.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_C98 PF15499.6 GAP92485.1 - 0.083 12.4 0.3 0.49 9.8 0.0 2.2 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase VHS PF00790.19 GAP92486.1 - 1e-40 138.8 1.7 1.4e-39 135.1 0.1 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 GAP92486.1 - 1.8e-14 53.6 5.1 3.2e-14 52.8 5.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 GAP92486.1 - 1.2e-06 28.0 12.4 0.0026 17.5 1.5 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 GAP92486.1 - 4.7e-05 23.6 0.0 0.00021 21.5 0.0 2.2 1 0 0 1 1 1 1 GAT domain GTP_EFTU PF00009.27 GAP92487.1 - 1.3e-45 155.4 0.0 2e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 GAP92487.1 - 1.7e-24 85.9 1.2 3.3e-24 85.0 1.2 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 GAP92487.1 - 1.7e-08 34.5 0.0 0.0002 21.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 GAP92487.1 - 4e-08 33.5 0.2 3.3e-07 30.6 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAP92487.1 - 6e-07 29.8 0.3 2.6e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Roc PF08477.13 GAP92487.1 - 0.00082 19.6 0.4 0.09 13.0 0.0 2.8 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 GAP92487.1 - 0.005 16.3 0.0 0.2 11.0 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 GAP92487.1 - 0.05 13.2 0.2 0.85 9.2 0.0 2.6 3 0 0 3 3 3 0 Ras family FeoB_N PF02421.18 GAP92487.1 - 0.13 11.8 0.0 2.5 7.6 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B HSP70 PF00012.20 GAP92488.1 - 7.2e-263 873.2 10.6 8.2e-263 873.0 10.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 GAP92488.1 - 5.7e-19 68.1 0.2 7.6e-17 61.1 0.0 2.2 1 1 1 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 GAP92488.1 - 0.0011 19.3 1.0 7.3 7.1 0.0 3.6 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 GAP92488.1 - 0.017 14.4 0.4 0.39 9.9 0.1 2.4 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DDR PF08841.10 GAP92488.1 - 0.033 13.2 0.1 0.19 10.7 0.1 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF2015 PF09435.10 GAP92488.1 - 0.12 12.3 0.9 0.3 10.9 0.9 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) FGGY_C PF02782.16 GAP92488.1 - 0.13 11.9 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.11 GAP92488.1 - 0.34 10.1 5.7 0.037 13.3 1.4 1.5 2 0 0 2 2 2 0 Radial spoke protein 3 Sugar_tr PF00083.24 GAP92489.1 - 2.4e-33 115.7 31.7 6.9e-18 64.7 11.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 GAP92489.1 - 1.2e-22 80.4 43.7 5.8e-13 48.5 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MASE2 PF05230.11 GAP92489.1 - 0.24 11.5 2.6 0.44 10.6 0.1 2.8 3 0 0 3 3 3 0 MASE2 domain Helicase_C PF00271.31 GAP92491.1 - 5.6e-11 42.8 0.0 2.6e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 GAP92491.1 - 7.8e-08 32.3 0.0 1.9e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 GAP92491.1 - 0.003 16.4 0.0 0.0046 15.8 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer OMP_b-brl_2 PF13568.6 GAP92492.1 - 3.4 7.7 7.5 43 4.1 3.7 2.8 2 1 1 3 3 3 0 Outer membrane protein beta-barrel domain PT PF04886.12 GAP92493.1 - 0.017 14.6 41.3 0.12 12.0 8.8 4.2 2 1 0 2 2 2 0 PT repeat TMP_2 PF06791.13 GAP92493.1 - 1.9 8.1 25.3 3 7.5 25.1 1.4 1 1 0 1 1 1 0 Prophage tail length tape measure protein Pkinase PF00069.25 GAP92494.1 - 2.3e-39 135.3 0.0 4.3e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92494.1 - 6.8e-19 68.2 0.0 1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 GAP92494.1 - 8e-06 26.1 0.9 2.4e-05 24.6 0.1 2.2 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 GAP92494.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-C3H1 PF10650.9 GAP92495.1 - 0.27 11.0 0.8 0.52 10.1 0.8 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain Pkinase PF00069.25 GAP92496.1 - 2.8e-10 40.0 0.0 1.6e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 GAP92496.1 - 0.0012 18.2 0.2 0.0038 16.6 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 GAP92496.1 - 0.0015 17.8 0.5 0.039 13.2 0.5 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP92496.1 - 0.088 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FAD_binding_4 PF01565.23 GAP92497.1 - 1.4e-18 67.0 0.3 2.3e-18 66.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DUF4974 PF16344.5 GAP92498.1 - 0.19 11.7 0.1 0.45 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) SKG6 PF08693.10 GAP92499.1 - 0.068 12.6 6.2 0.039 13.4 3.2 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Fungal_trans PF04082.18 GAP92500.1 - 1.8e-11 43.6 0.0 3.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP92500.1 - 5.8e-06 26.3 13.6 1.6e-05 24.9 13.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MMM1 PF10296.9 GAP92502.1 - 3.2e-07 29.7 0.4 4.1e-06 26.1 0.0 2.2 1 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 DNA_pol_B PF00136.21 GAP92503.1 - 7e-104 348.1 0.0 9.4e-104 347.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 GAP92503.1 - 8.3e-21 74.5 0.0 1.7e-11 43.9 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 GAP92503.1 - 2.9e-17 62.9 2.4 7.3e-17 61.6 2.4 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 GAP92503.1 - 2 8.5 4.2 4.6 7.3 4.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon Slu7 PF11708.8 GAP92504.1 - 2.1e-74 250.6 17.7 2.1e-74 250.6 17.7 2.7 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 GAP92504.1 - 0.041 13.6 0.6 0.073 12.8 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle S4 PF01479.25 GAP92505.1 - 2.3e-12 46.4 0.9 2.3e-12 46.4 0.9 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 GAP92505.1 - 1e-05 26.3 0.1 1.9e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 GAP92506.1 - 5.5e-48 161.0 5.2 1.7e-47 159.4 3.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L21e DUF3999 PF13163.6 GAP92507.1 - 0.038 13.2 1.3 0.042 13.1 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) p450 PF00067.22 GAP92508.1 - 2.4e-61 207.9 0.0 3.4e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 GAP92509.1 - 2.6e-07 30.6 10.6 2.6e-07 30.6 10.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1265 PF06887.14 GAP92509.1 - 0.082 12.9 0.2 0.52 10.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) DUF4043 PF13252.6 GAP92510.1 - 0.0068 15.6 0.0 0.0098 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4043) Sugar_tr PF00083.24 GAP92511.1 - 3.9e-97 326.0 31.3 4.5e-97 325.8 31.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP92511.1 - 3.1e-24 85.6 34.0 3.1e-24 85.6 34.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 GAP92512.1 - 8.1e-23 81.5 0.7 1.6e-22 80.6 0.7 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 GAP92512.1 - 1.6e-07 31.5 0.0 4.8e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA_C PF02894.17 GAP92512.1 - 5.4e-06 26.4 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_7 PF13241.6 GAP92512.1 - 0.00074 19.9 0.2 0.0016 18.8 0.2 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding CoA_binding PF02629.19 GAP92512.1 - 0.056 14.1 0.1 0.13 13.0 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain Gp_dh_N PF00044.24 GAP92512.1 - 0.057 13.8 0.0 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 GAP92512.1 - 0.088 13.0 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SUR7 PF06687.12 GAP92513.1 - 1.7e-28 99.7 13.3 2.4e-28 99.3 13.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family PhoLip_ATPase_C PF16212.5 GAP92513.1 - 0.0052 16.6 2.4 0.0079 16.0 2.4 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal DUF4381 PF14316.6 GAP92513.1 - 0.045 14.0 0.3 0.045 14.0 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) CobD_Cbib PF03186.13 GAP92513.1 - 0.096 11.9 2.1 0.41 9.8 2.9 1.6 2 0 0 2 2 2 0 CobD/Cbib protein SirB PF04247.12 GAP92513.1 - 2.4 8.2 11.0 5.3 7.2 11.0 1.5 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB ABC1 PF03109.16 GAP92514.1 - 3.9e-22 78.6 0.0 8.3e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 GAP92514.1 - 2.2e-05 24.5 0.0 4.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Septin PF00735.18 GAP92515.1 - 8.9e-31 107.2 0.0 2.7e-09 36.7 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 GAP92515.1 - 0.0018 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 GAP92515.1 - 0.0051 17.2 0.1 0.017 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 GAP92515.1 - 0.012 14.7 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 GAP92515.1 - 0.03 14.9 0.1 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 GAP92515.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein KAP_NTPase PF07693.14 GAP92515.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Roc PF08477.13 GAP92515.1 - 0.18 12.0 0.0 0.59 10.4 0.0 1.9 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 GAP92515.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 GAP92515.1 - 0.42 10.6 1.5 0.85 9.6 0.2 2.2 2 1 0 2 2 2 0 Dynamin family Nop14 PF04147.12 GAP92515.1 - 0.78 7.9 8.6 1.1 7.4 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAP92515.1 - 9.1 4.4 8.5 13 3.9 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1996 PF09362.10 GAP92516.1 - 3.8e-80 269.3 1.8 4.6e-80 269.0 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Caps_synth PF05704.12 GAP92517.1 - 3.9e-09 36.3 0.0 8.7e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 GAP92517.1 - 1.9e-05 25.2 0.0 3.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 GAP92517.1 - 0.18 11.0 0.1 0.29 10.4 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Abhydrolase_3 PF07859.13 GAP92518.1 - 2e-56 191.2 0.4 2.9e-56 190.6 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 GAP92518.1 - 1.1e-08 34.4 0.6 1.1e-07 31.2 0.6 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 GAP92518.1 - 0.0037 16.8 0.0 0.04 13.4 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2974 PF11187.8 GAP92518.1 - 0.071 12.7 0.5 0.18 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 GAP92518.1 - 0.14 11.8 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ank_3 PF13606.6 GAP92519.1 - 1.3e-05 25.2 0.6 22 6.0 0.0 6.2 7 1 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 GAP92519.1 - 3.4e-05 24.3 0.0 1.3 9.7 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP92519.1 - 0.00049 20.6 0.0 1.2 9.8 0.0 3.8 2 2 2 4 4 4 1 Ankyrin repeats (3 copies) Zn_clus PF00172.18 GAP92520.1 - 4.2e-08 33.2 11.9 4.2e-08 33.2 11.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT_3 PF13622.6 GAP92521.1 - 4e-64 217.3 2.4 5.4e-64 216.8 2.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 GAP92521.1 - 1.2e-16 60.7 0.0 0.00036 20.4 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Oxysterol_BP PF01237.18 GAP92522.1 - 3.2e-127 424.4 0.1 2.4e-126 421.6 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 GAP92522.1 - 6e-20 71.6 0.0 7e-10 39.4 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP92522.1 - 9.2e-18 64.1 0.1 1.9e-10 40.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP92522.1 - 7.1e-14 50.6 0.0 0.00012 22.2 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 GAP92522.1 - 5.8e-13 48.6 0.1 0.00072 19.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.29 GAP92522.1 - 9.6e-13 48.6 0.6 1.9e-12 47.6 0.6 1.5 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 GAP92522.1 - 9.9e-12 45.1 0.0 2.2e-07 31.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH_8 PF15409.6 GAP92522.1 - 2.9e-08 33.9 0.9 6.9e-08 32.7 0.9 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 GAP92522.1 - 2.9e-05 24.4 3.0 7.1e-05 23.2 3.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_A22B PF04258.13 GAP92524.1 - 1.2e-54 185.8 3.5 2.6e-35 122.4 0.5 2.4 2 1 0 2 2 2 2 Signal peptide peptidase Pro_isomerase PF00160.21 GAP92525.1 - 2.4e-50 170.9 0.0 2.8e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf_UBZ PF18439.1 GAP92526.1 - 0.16 11.6 2.3 2 8.1 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 GAP92526.1 - 0.56 9.8 7.2 0.13 11.9 2.5 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Acetyltransf_1 PF00583.25 GAP92527.1 - 8.6e-07 29.2 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP92527.1 - 0.0083 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HET PF06985.11 GAP92528.1 - 9.2e-25 87.7 0.2 1.6e-24 86.9 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SET PF00856.28 GAP92529.1 - 1.5e-18 67.8 0.0 8.6e-18 65.3 0.0 2.1 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 GAP92529.1 - 5.5e-16 59.2 7.7 7.1e-16 58.8 4.7 2.2 2 0 0 2 2 2 1 Pre-SET motif AWS PF17907.1 GAP92529.1 - 0.0082 16.2 2.1 0.0082 16.2 2.1 2.3 2 0 0 2 2 2 1 AWS domain EGF_alliinase PF04863.13 GAP92529.1 - 2.3 8.7 11.0 2.8 8.4 0.2 2.6 2 0 0 2 2 2 0 Alliinase EGF-like domain Lipoxygenase PF00305.19 GAP92530.1 - 1.2e-22 80.1 0.0 1.8e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase Adenylsucc_synt PF00709.21 GAP92531.1 - 2.8e-162 540.4 0.0 3.2e-162 540.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Rubredoxin PF00301.20 GAP92531.1 - 0.11 12.5 0.0 0.79 9.8 0.0 2.3 1 1 1 2 2 2 0 Rubredoxin Cor1 PF04803.12 GAP92531.1 - 0.15 12.3 0.1 0.25 11.6 0.1 1.2 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Nop52 PF05997.12 GAP92532.1 - 3.2e-47 161.1 0.0 1.6e-42 145.7 0.0 2.0 2 0 0 2 2 2 2 Nucleolar protein,Nop52 DUF4611 PF15387.6 GAP92532.1 - 0.28 11.4 7.2 2.9 8.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Importin_rep_4 PF18808.1 GAP92532.1 - 1.5 9.2 5.5 27 5.1 0.1 2.6 2 0 0 2 2 2 0 Importin repeat DAGK_cat PF00781.24 GAP92533.1 - 5.2e-25 87.5 0.1 8e-25 86.9 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain 4HBT_3 PF13622.6 GAP92534.1 - 1e-53 183.2 1.9 1.2e-53 183.0 1.9 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 GAP92534.1 - 6e-05 23.3 1.6 0.00011 22.4 1.6 1.5 1 0 0 1 1 1 1 Thioesterase superfamily MCR_C PF04609.12 GAP92534.1 - 0.1 11.7 0.3 0.17 11.0 0.3 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C THOC2_N PF16134.5 GAP92535.1 - 8.2e-213 708.6 0.0 1.1e-212 708.1 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 GAP92535.1 - 6.9e-88 294.7 0.0 1.1e-87 294.1 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 GAP92535.1 - 1.3e-27 95.7 0.1 2.5e-27 94.7 0.1 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF4712 PF15830.5 GAP92535.1 - 0.04 13.6 0.1 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) Abhydrolase_1 PF00561.20 GAP92536.1 - 2.8e-49 168.1 0.0 4.2e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP92536.1 - 5.9e-05 23.8 4.7 0.00011 22.8 4.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP92536.1 - 0.072 12.3 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 GAP92536.1 - 0.23 10.3 0.0 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Sugar_tr PF00083.24 GAP92537.1 - 8.1e-54 183.2 12.7 1.6e-53 182.2 12.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP92537.1 - 5.8e-27 94.5 19.7 5.8e-27 94.5 19.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 GAP92537.1 - 0.0047 15.8 2.5 0.91 8.3 0.2 2.6 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 GAP92537.1 - 7.5 5.0 22.3 0.019 13.5 8.3 2.6 3 1 0 3 3 3 0 MFS/sugar transport protein Cyclin_N PF00134.23 GAP92539.1 - 0.00016 21.4 0.0 0.00046 19.9 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Amidohydro_2 PF04909.14 GAP92540.1 - 8.8e-09 35.5 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase CoA_binding_2 PF13380.6 GAP92540.1 - 0.0029 18.1 0.1 0.0063 17.0 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Amidohydro_1 PF01979.20 GAP92540.1 - 0.0045 16.4 0.0 0.022 14.1 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Adenylsucc_synt PF00709.21 GAP92541.1 - 6.1e-159 529.4 0.0 7e-159 529.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MBD PF01429.19 GAP92541.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyl-CpG binding domain DUF1548 PF07579.11 GAP92541.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Peptidase_M20 PF01546.28 GAP92544.1 - 7.3e-28 97.7 0.0 1.1e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 GAP92544.1 - 3.1e-08 33.5 0.0 6.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 GAP92544.1 - 0.0033 17.2 0.0 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 Rhomboid PF01694.22 GAP92545.1 - 2.4e-22 79.6 8.9 2.4e-22 79.6 8.9 1.6 2 0 0 2 2 2 1 Rhomboid family PhoD PF09423.10 GAP92546.1 - 4.1e-05 22.8 0.7 0.0014 17.7 0.0 2.6 3 0 0 3 3 3 2 PhoD-like phosphatase ATP-synt_J PF04911.12 GAP92546.1 - 0.58 9.8 2.2 0.79 9.4 0.6 2.0 2 0 0 2 2 2 0 ATP synthase j chain Aldedh PF00171.22 GAP92547.1 - 6e-107 358.0 0.0 7.6e-107 357.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family EHN PF06441.12 GAP92548.1 - 1.7e-35 121.6 0.1 4.8e-34 117.0 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 GAP92548.1 - 1.6e-13 50.9 0.1 3e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP92548.1 - 0.085 13.5 20.7 0.012 16.3 15.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family Acyl_transf_3 PF01757.22 GAP92549.1 - 1.1e-15 57.6 18.8 1.1e-15 57.6 18.8 2.7 2 1 0 2 2 2 2 Acyltransferase family DUF1962 PF09227.10 GAP92550.1 - 1.8e-36 124.3 21.6 2.1e-36 124.0 21.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1962) Stealth_CR2 PF11380.8 GAP92551.1 - 2.5e-16 59.8 0.2 7.3e-15 55.1 0.2 2.7 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 GAP92551.1 - 7.6e-09 35.1 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 GAP92551.1 - 7.9e-06 25.7 0.0 3.4e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 GAP92551.1 - 0.12 12.3 2.7 0.31 11.0 2.7 1.8 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 DUF3439 PF11921.8 GAP92551.1 - 0.37 10.8 7.0 0.95 9.4 7.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Acyl_transf_3 PF01757.22 GAP92552.1 - 1.1e-31 110.1 33.7 1.5e-31 109.7 33.7 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF1485 PF07364.12 GAP92554.1 - 1.8e-64 217.8 12.4 4.3e-64 216.6 10.1 2.3 1 1 1 2 2 2 2 Metallopeptidase family M81 MlrC_C PF07171.12 GAP92554.1 - 2.3e-37 128.9 8.3 1.4e-30 106.7 8.3 3.5 1 1 0 1 1 1 1 MlrC C-terminus ketoacyl-synt PF00109.26 GAP92555.1 - 3.8e-75 252.7 0.0 1.1e-74 251.2 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 GAP92555.1 - 5.2e-71 239.5 0.0 9.8e-71 238.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 GAP92555.1 - 7e-58 196.4 0.0 1.1e-57 195.7 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 GAP92555.1 - 2.2e-48 164.5 0.0 5.1e-47 160.1 0.0 3.0 3 0 0 3 3 2 1 KR domain Acyl_transf_1 PF00698.21 GAP92555.1 - 1.1e-42 146.7 0.0 2e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 GAP92555.1 - 2.1e-41 142.1 0.0 3.7e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.12 GAP92555.1 - 3e-34 118.4 0.0 7e-34 117.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 GAP92555.1 - 3.4e-28 98.0 0.0 9.9e-28 96.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 GAP92555.1 - 3.6e-18 66.1 0.0 3.8e-17 62.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 GAP92555.1 - 2.1e-17 63.2 0.5 5.3e-09 36.3 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 GAP92555.1 - 1.1e-16 61.1 0.0 1e-12 48.1 0.0 2.7 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 GAP92555.1 - 2.2e-16 60.3 0.0 3.2e-15 56.5 0.0 2.7 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 GAP92555.1 - 8e-14 52.1 0.0 3.5e-13 50.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP92555.1 - 1.9e-13 50.9 0.0 9.8e-13 48.6 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP92555.1 - 3.1e-12 46.7 0.0 7e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP92555.1 - 9.5e-10 38.5 0.0 2.6e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAP92555.1 - 6.5e-09 35.5 0.0 1.6e-07 30.9 0.0 3.4 4 0 0 4 4 4 1 short chain dehydrogenase 3Beta_HSD PF01073.19 GAP92555.1 - 1.4e-08 34.1 0.0 3.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 GAP92555.1 - 0.0001 21.7 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 GAP92555.1 - 0.00015 21.2 0.1 0.00031 20.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 GAP92555.1 - 0.00054 19.8 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 GAP92555.1 - 0.038 15.0 0.0 0.22 12.6 0.0 2.5 1 0 0 1 1 1 0 Methyltransferase domain GDP_Man_Dehyd PF16363.5 GAP92555.1 - 0.053 12.9 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 GAP92555.1 - 0.13 13.2 0.0 0.46 11.5 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain EthD PF07110.11 GAP92556.1 - 1.7e-10 41.9 0.0 2.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.16 GAP92558.1 - 2.3e-36 125.5 58.3 6.1e-36 124.1 58.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 GAP92558.1 - 6.7e-14 51.2 17.8 8.3e-14 50.9 17.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_28 PF00295.17 GAP92559.1 - 7.8e-42 143.5 0.5 4.6e-41 140.9 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 GAP92559.1 - 0.00036 20.4 1.5 0.00036 20.4 1.5 3.1 2 2 1 3 3 3 2 Right handed beta helix region Bac_rhamnosid6H PF17389.2 GAP92560.1 - 9.9e-22 77.6 2.6 2.4e-18 66.5 0.9 2.1 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 GAP92560.1 - 3.1e-08 33.3 0.0 1.4e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 GAP92560.1 - 0.00099 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Trehalase Isochorismatase PF00857.20 GAP92561.1 - 1.5e-16 61.1 0.0 4e-16 59.7 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family Sugar_tr PF00083.24 GAP92562.1 - 9.8e-126 420.2 24.0 1.1e-125 420.0 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP92562.1 - 1.6e-20 73.4 53.6 1.1e-18 67.3 30.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0242 PF06785.11 GAP92562.1 - 2 8.5 3.3 2.8 8.0 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF3792 PF12670.7 GAP92562.1 - 8.7 6.5 34.5 0.037 14.2 6.9 4.7 3 2 1 4 4 4 0 Protein of unknown function (DUF3792) MmgE_PrpD PF03972.14 GAP92563.1 - 8.9e-106 354.1 5.0 1.1e-105 353.8 5.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Meth_synt_2 PF01717.18 GAP92564.1 - 3.7e-08 33.0 0.0 2.2e-06 27.2 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain DUF4573 PF15140.6 GAP92565.1 - 1.6e-09 37.8 0.6 7.7e-06 25.8 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) Tcp10_C PF07202.13 GAP92565.1 - 0.017 15.1 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 T-complex protein 10 C-terminus Cupin_3 PF05899.12 GAP92565.1 - 4.7 7.0 4.9 78 3.1 0.1 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF861) DNA_methylase PF00145.17 GAP92566.1 - 1.5e-35 123.2 0.0 2.7e-26 92.7 0.0 2.2 1 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 GAP92566.1 - 0.046 13.3 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Mannosyl_trans3 PF11051.8 GAP92567.1 - 4.9e-57 193.4 0.0 5.4e-56 190.0 0.0 2.4 1 1 0 1 1 1 1 Mannosyltransferase putative Ant_C PF05586.11 GAP92567.1 - 1.6 9.4 4.1 23 5.7 4.1 2.3 1 1 0 1 1 1 0 Anthrax receptor C-terminus region F-box-like PF12937.7 GAP92569.1 - 0.11 12.4 4.2 3.4 7.6 4.2 2.9 1 1 0 1 1 1 0 F-box-like PP2 PF14299.6 GAP92571.1 - 0.12 12.4 0.8 0.22 11.5 0.8 1.4 1 0 0 1 1 1 0 Phloem protein 2 Ysc84 PF04366.12 GAP92572.1 - 2.7e-41 140.3 0.2 4.8e-41 139.5 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 GAP92572.1 - 2.5e-13 49.4 0.3 6.8e-13 48.0 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 GAP92572.1 - 2.1e-12 46.5 0.0 4.9e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 GAP92572.1 - 7.5e-12 44.9 0.0 1.7e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 GAP92572.1 - 0.011 15.4 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Synaptobrevin PF00957.21 GAP92573.1 - 0.0039 16.9 0.9 0.018 14.8 0.5 1.9 1 1 1 2 2 2 2 Synaptobrevin ArfGap PF01412.18 GAP92575.1 - 9.5e-41 138.6 0.3 1.2e-40 138.2 0.3 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 GAP92575.1 - 0.0039 16.9 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 Partial cleavage stimulation factor domain DND1_DSRM PF14709.7 GAP92576.1 - 0.035 14.4 0.6 0.3 11.4 0.6 2.0 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 GAP92576.1 - 0.074 13.8 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 Double-stranded RNA binding motif Ribosomal_S7 PF00177.21 GAP92577.1 - 4.6e-25 88.0 0.0 7.6e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF3439 PF11921.8 GAP92577.1 - 0.79 9.7 13.1 1.5 8.8 13.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 GAP92577.1 - 7.8 4.6 14.2 11 4.1 14.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ran-binding PF05508.11 GAP92578.1 - 1.6e-58 198.2 0.0 2e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.27 GAP92579.1 - 4e-40 137.4 0.0 6.5e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 GAP92579.1 - 2.5e-27 95.4 0.1 6e-27 94.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 GAP92579.1 - 1.1e-06 28.9 1.5 4.8e-06 26.9 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAP92579.1 - 0.0068 16.5 0.0 0.034 14.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase TAF4 PF05236.14 GAP92579.1 - 0.61 9.8 5.8 1.3 8.7 5.8 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family UCH_1 PF13423.6 GAP92580.1 - 9.5e-101 337.6 0.3 1.4e-100 337.0 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 GAP92580.1 - 5e-17 62.9 0.0 9.1e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 GAP92580.1 - 7e-05 22.4 0.0 0.00016 21.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ima1_N PF09779.9 GAP92580.1 - 0.064 14.1 0.5 0.15 12.9 0.5 1.6 1 0 0 1 1 1 0 Ima1 N-terminal domain PEPCK_ATP PF01293.20 GAP92581.1 - 5.5e-216 717.7 0.0 6.5e-216 717.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 GAP92581.1 - 0.05 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Ank_2 PF12796.7 GAP92583.1 - 3.5e-09 37.1 0.0 0.1 13.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP92583.1 - 5.5e-07 29.4 1.0 15 6.6 0.0 6.1 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 GAP92583.1 - 8.6e-07 29.4 0.1 4.4 8.0 0.0 6.1 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 GAP92583.1 - 0.00025 21.3 0.0 0.57 10.7 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 GAP92583.1 - 0.081 13.3 0.1 7.6 7.0 0.0 3.8 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Fungal_trans PF04082.18 GAP92584.1 - 8.3e-21 74.2 0.1 1.3e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltr_RsmB-F PF01189.17 GAP92585.1 - 1.1e-19 70.9 0.0 5.2e-19 68.7 0.0 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF2722 PF10846.8 GAP92585.1 - 0.0089 15.0 6.4 0.012 14.5 6.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) FtsJ PF01728.19 GAP92585.1 - 0.024 14.8 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PAXIP1_C PF15364.6 GAP92585.1 - 0.05 13.9 1.0 0.092 13.1 1.0 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein TFIIA PF03153.13 GAP92585.1 - 0.065 13.2 10.0 0.093 12.7 10.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0560 PF10577.9 GAP92585.1 - 0.11 11.0 3.5 0.17 10.4 3.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Spt20 PF12090.8 GAP92585.1 - 0.15 11.6 13.7 0.22 11.1 13.7 1.1 1 0 0 1 1 1 0 Spt20 family AAA_13 PF13166.6 GAP92587.1 - 0.12 11.0 0.9 0.18 10.4 0.9 1.1 1 0 0 1 1 1 0 AAA domain Usp PF00582.26 GAP92588.1 - 5e-24 85.4 6.7 1e-22 81.1 1.9 2.9 2 1 0 2 2 2 1 Universal stress protein family Peptidase_S8 PF00082.22 GAP92590.1 - 1.9e-13 50.4 0.0 7.3e-13 48.4 0.0 1.9 1 1 0 1 1 1 1 Subtilase family WD40 PF00400.32 GAP92591.1 - 3e-51 170.2 23.6 3.3e-08 34.0 0.1 8.3 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP92591.1 - 2.9e-12 46.7 0.1 0.031 14.6 0.1 5.9 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP92591.1 - 0.0048 15.9 0.1 16 4.3 0.0 4.6 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 GAP92591.1 - 0.0058 16.0 0.0 2.7 7.2 0.0 3.9 3 1 1 5 5 5 1 WD40-like domain Nup160 PF11715.8 GAP92591.1 - 0.031 12.9 1.0 2.2 6.8 0.1 3.3 2 1 2 4 4 4 0 Nucleoporin Nup120/160 NUMOD4 PF07463.11 GAP92591.1 - 0.14 12.3 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 NUMOD4 motif AAA PF00004.29 GAP92593.1 - 3e-16 60.0 0.0 5.6e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP92593.1 - 7e-05 23.3 0.0 0.00018 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP92593.1 - 0.00022 21.5 0.0 0.00095 19.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 GAP92593.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CPT PF07931.12 GAP92593.1 - 0.12 12.2 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Hydin_ADK PF17213.3 GAP92593.1 - 4.6 7.5 4.4 0.84 9.9 0.1 1.8 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Methyltransf_2 PF00891.18 GAP92595.1 - 3.3e-20 72.3 0.0 3.9e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DUF3328 PF11807.8 GAP92596.1 - 0.0035 17.1 1.9 0.0053 16.6 0.8 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Methyltransf_2 PF00891.18 GAP92597.1 - 2.4e-24 85.8 0.0 7.8e-14 51.5 0.0 2.2 1 1 1 2 2 2 2 O-methyltransferase domain Mucin PF01456.17 GAP92597.1 - 0.0069 16.4 21.0 0.0069 16.4 21.0 2.8 3 0 0 3 3 3 1 Mucin-like glycoprotein Methyltransf_25 PF13649.6 GAP92597.1 - 0.0095 16.6 0.1 0.66 10.7 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP92597.1 - 0.031 14.1 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SSP160 PF06933.11 GAP92597.1 - 0.072 11.3 18.5 0.12 10.6 18.5 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FSA_C PF10479.9 GAP92597.1 - 2.8 6.0 8.0 0.78 7.8 5.1 1.4 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus AJAP1_PANP_C PF15298.6 GAP92597.1 - 6.4 6.9 14.7 1.5 9.0 11.3 1.7 2 0 0 2 2 2 0 AJAP1/PANP C-terminus DUF3328 PF11807.8 GAP92598.1 - 3.3e-40 138.2 2.8 4.4e-40 137.8 2.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NAD_binding_8 PF13450.6 GAP92599.1 - 1.5e-05 25.1 0.3 1.5e-05 25.1 0.3 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAP92599.1 - 1.8e-05 24.2 1.2 0.037 13.3 1.4 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAP92599.1 - 0.0021 17.7 1.9 0.0021 17.7 1.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP92599.1 - 0.0035 16.6 0.1 0.0059 15.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP92599.1 - 0.13 12.8 0.1 0.4 11.3 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase JAB PF01398.21 GAP92600.1 - 2.6e-13 50.0 0.0 4.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 GAP92600.1 - 1.4e-11 44.6 0.1 2.5e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 GAP92600.1 - 9e-05 22.2 0.0 0.00023 20.9 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Prefoldin_2 PF01920.20 GAP92601.1 - 1.2e-18 66.9 12.3 1.5e-18 66.7 12.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit Spc7 PF08317.11 GAP92601.1 - 0.0015 17.5 7.5 0.0018 17.2 7.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Prefoldin PF02996.17 GAP92601.1 - 0.0052 16.7 6.8 0.027 14.4 0.2 2.2 2 0 0 2 2 2 1 Prefoldin subunit DUF4407 PF14362.6 GAP92601.1 - 0.0057 16.1 4.8 0.0073 15.7 4.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Bcr-Abl_Oligo PF09036.10 GAP92601.1 - 0.017 15.1 1.1 0.051 13.6 0.0 2.1 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain JAKMIP_CC3 PF16034.5 GAP92601.1 - 0.037 14.0 6.7 0.6 10.0 1.4 2.1 2 0 0 2 2 2 0 JAKMIP CC3 domain WEMBL PF05701.11 GAP92601.1 - 0.058 12.1 10.6 0.46 9.1 4.0 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light TMPIT PF07851.13 GAP92601.1 - 0.17 11.1 2.8 0.21 10.8 2.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spc24 PF08286.11 GAP92601.1 - 0.18 12.0 5.4 1.5 9.1 1.0 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 T3SS_needle_E PF08988.10 GAP92601.1 - 0.22 11.7 5.3 6.4 7.0 2.1 2.4 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Tropomyosin_1 PF12718.7 GAP92601.1 - 0.26 11.4 12.7 13 5.9 12.9 2.1 1 1 0 1 1 1 0 Tropomyosin like FlaC_arch PF05377.11 GAP92601.1 - 0.29 11.5 5.9 21 5.6 0.2 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Hrs_helical PF12210.8 GAP92601.1 - 0.33 11.5 4.8 0.85 10.2 1.7 2.2 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DHR10 PF18595.1 GAP92601.1 - 0.37 10.8 11.1 0.78 9.8 4.0 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain End3 PF12761.7 GAP92601.1 - 0.44 10.7 9.3 0.55 10.4 9.3 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Rho_Binding PF08912.11 GAP92601.1 - 0.68 10.8 9.2 4.3 8.2 0.2 2.2 2 0 0 2 2 2 0 Rho Binding Cep57_MT_bd PF06657.13 GAP92601.1 - 0.77 10.3 9.4 6.3 7.3 0.3 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Osmo_CC PF08946.10 GAP92601.1 - 1.4 9.2 10.8 3.1 8.1 1.8 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil OmpH PF03938.14 GAP92601.1 - 1.7 9.0 17.7 1.3 9.4 1.5 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) JIP_LZII PF16471.5 GAP92601.1 - 1.7 8.9 7.5 0.83 9.9 1.3 2.5 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Bap31_Bap29_C PF18035.1 GAP92601.1 - 1.8 8.6 13.8 5.4 7.1 1.9 2.5 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain NPV_P10 PF05531.12 GAP92601.1 - 1.8 9.1 6.2 16 6.1 2.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HAP1_N PF04849.13 GAP92601.1 - 2.8 7.1 11.9 1.4 8.1 1.4 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DivIC PF04977.15 GAP92601.1 - 3.2 7.6 16.7 8.9 6.2 8.2 3.0 2 1 0 2 2 2 0 Septum formation initiator COG2 PF06148.11 GAP92601.1 - 3.8 7.6 7.8 5.4 7.1 3.4 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4140 PF13600.6 GAP92601.1 - 6.6 7.2 11.9 13 6.3 4.2 2.2 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA PF00004.29 GAP92602.1 - 3.1e-42 144.1 0.0 5.3e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 GAP92602.1 - 1.2e-28 98.8 0.2 4.1e-28 97.2 0.2 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 GAP92602.1 - 1.4e-22 79.5 1.2 3.6e-22 78.2 1.2 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 GAP92602.1 - 2.5e-05 24.1 0.0 7e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 GAP92602.1 - 2.6e-05 24.7 0.1 0.0019 18.6 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 GAP92602.1 - 3.6e-05 23.8 0.0 0.00023 21.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 GAP92602.1 - 3.7e-05 24.0 0.0 0.011 16.1 0.0 3.0 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 GAP92602.1 - 6.9e-05 22.7 0.0 0.00017 21.3 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 GAP92602.1 - 0.0001 22.6 0.1 0.02 15.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 GAP92602.1 - 0.00024 20.4 0.0 0.00044 19.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_lid_3 PF17862.1 GAP92602.1 - 0.00028 20.6 0.0 0.0014 18.4 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 GAP92602.1 - 0.00042 20.3 0.0 0.00089 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAP92602.1 - 0.00054 19.2 0.0 0.0013 18.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 GAP92602.1 - 0.0012 19.1 0.0 0.0046 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAP92602.1 - 0.0013 19.3 0.0 0.0041 17.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 GAP92602.1 - 0.0021 17.8 0.0 0.0082 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 GAP92602.1 - 0.0033 17.5 0.0 0.01 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 GAP92602.1 - 0.0046 16.6 0.2 0.74 9.4 0.1 2.8 2 1 0 3 3 3 1 AAA domain AAA_17 PF13207.6 GAP92602.1 - 0.019 15.4 0.0 0.055 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 GAP92602.1 - 0.021 14.3 0.1 0.11 12.0 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 GAP92602.1 - 0.029 13.7 0.0 0.082 12.3 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 GAP92602.1 - 0.046 13.8 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 1 0 Torsin NACHT PF05729.12 GAP92602.1 - 0.065 13.2 0.0 0.33 10.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain ATPase_2 PF01637.18 GAP92602.1 - 0.075 12.9 0.1 1.1 9.1 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 GAP92602.1 - 0.085 12.3 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 GAP92602.1 - 0.099 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 GAP92602.1 - 0.12 12.1 0.2 0.96 9.1 0.1 2.2 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activat PF00158.26 GAP92602.1 - 0.13 12.0 0.0 0.47 10.1 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 GAP92602.1 - 0.14 11.5 0.0 10 5.4 0.0 2.3 1 1 1 2 2 2 0 KaiC Zeta_toxin PF06414.12 GAP92602.1 - 0.15 11.3 0.1 1.7 7.9 0.1 2.2 1 1 1 2 2 2 0 Zeta toxin Nop PF01798.18 GAP92603.1 - 1e-81 273.8 0.0 1e-81 273.8 0.0 2.0 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAP92603.1 - 1.2e-15 57.6 0.1 1.2e-15 57.6 0.1 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 GAP92603.1 - 0.059 13.4 24.6 0.14 12.2 24.6 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 GAP92603.1 - 0.96 9.2 15.9 1.7 8.4 15.9 1.3 1 0 0 1 1 1 0 Coilin N-terminus RR_TM4-6 PF06459.12 GAP92603.1 - 9.7 5.9 14.1 16 5.2 14.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_hydro_114 PF03537.13 GAP92604.1 - 9.5e-79 264.0 0.3 1.2e-78 263.7 0.3 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Glyco_hydro_18 PF00704.28 GAP92606.1 - 1.9e-86 290.7 0.0 2.2e-86 290.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.23 GAP92607.1 - 4.1e-34 116.2 0.6 7.8e-34 115.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 GAP92607.1 - 2.9e-26 91.3 2.1 2.9e-26 91.3 2.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 GAP92607.1 - 4.8e-16 58.3 0.7 4.8e-16 58.3 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 GAP92607.1 - 2.5e-05 24.6 0.8 0.00013 22.4 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 GAP92607.1 - 0.00068 19.7 0.9 0.0015 18.6 0.9 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 GAP92607.1 - 0.0051 17.1 1.2 0.0075 16.6 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 GAP92607.1 - 0.0054 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 GAP92607.1 - 0.01 16.4 1.1 0.015 15.9 1.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 GAP92607.1 - 0.017 15.1 1.0 5.8 7.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_S26e PF01283.19 GAP92608.1 - 5e-53 178.1 9.1 5.9e-53 177.9 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 GAP92608.1 - 0.028 14.4 1.2 0.055 13.4 0.0 2.1 3 0 0 3 3 3 0 Zinc binding domain DUF1918 PF08940.11 GAP92608.1 - 0.046 13.4 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF4668 PF15701.5 GAP92608.1 - 0.12 12.2 2.3 0.14 11.9 1.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) ELYS PF13934.6 GAP92609.1 - 1.4e-67 227.9 0.7 1.7e-67 227.7 0.7 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.19 GAP92610.1 - 1.3e-72 243.9 22.0 4.3e-38 131.0 0.8 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 GAP92610.1 - 7.7e-25 87.5 0.0 4.2e-24 85.1 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 GAP92610.1 - 2.7e-11 43.9 5.3 5.9e-05 23.0 0.0 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 GAP92610.1 - 1.7e-08 35.2 0.0 1.7e-08 35.2 0.0 7.0 3 2 3 6 6 6 1 AAA domain AAA_29 PF13555.6 GAP92610.1 - 0.00082 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DivIC PF04977.15 GAP92610.1 - 0.0031 17.2 2.7 0.0031 17.2 2.7 11.8 7 4 6 13 13 13 1 Septum formation initiator SbcCD_C PF13558.6 GAP92610.1 - 0.014 15.6 0.8 1.3 9.3 0.0 3.5 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 GAP92610.1 - 1.6 9.2 0.0 1.6 9.2 0.0 6.8 4 3 1 5 5 5 0 ABC transporter FRQ PF09421.10 GAP92611.1 - 0.0068 14.5 11.4 0.0086 14.2 11.4 1.0 1 0 0 1 1 1 1 Frequency clock protein p450 PF00067.22 GAP92612.1 - 4.8e-41 141.0 0.0 9.5e-25 87.2 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 Glyco_hydro_76 PF03663.14 GAP92613.1 - 1.5e-53 182.7 3.1 1.8e-53 182.4 3.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 GAP92613.1 - 6.5e-08 32.0 2.1 0.049 12.7 0.0 3.7 2 1 1 4 4 4 3 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 GAP92613.1 - 0.00035 19.2 0.0 0.1 11.1 0.1 2.2 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Frag1 PF10277.9 GAP92614.1 - 3e-13 49.8 1.6 3e-13 49.8 1.6 4.0 3 2 1 4 4 4 2 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.11 GAP92615.1 - 2.8e-25 88.2 1.1 8.2e-24 83.5 0.0 2.9 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 GAP92615.1 - 0.00023 20.4 0.8 0.00039 19.6 0.1 1.6 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 GAP92615.1 - 0.0052 17.5 0.4 4.2 8.4 0.0 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat EVE PF01878.18 GAP92616.1 - 1.6e-46 157.9 0.0 2.8e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 EVE domain ARID PF01388.21 GAP92618.1 - 6e-19 68.5 0.0 8.4e-18 64.8 0.0 2.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DUF2569 PF10754.9 GAP92619.1 - 3.7 8.0 9.0 2.6 8.5 6.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Acetyltransf_1 PF00583.25 GAP92620.1 - 3.4e-14 53.1 0.0 4.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP92620.1 - 6.3e-10 39.1 0.0 7.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP92620.1 - 2.1e-07 31.3 0.0 2.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP92620.1 - 0.0016 18.3 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 GAP92620.1 - 0.0081 16.3 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 GAP92620.1 - 0.023 14.8 0.1 0.058 13.5 0.1 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAP92620.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain HET PF06985.11 GAP92621.1 - 3.4e-06 27.5 0.0 1.1e-05 25.9 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LMBR1 PF04791.16 GAP92622.1 - 0.012 14.5 5.1 0.015 14.2 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Glyco_hydro_67N PF03648.14 GAP92622.1 - 0.015 15.5 0.7 0.036 14.4 0.4 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus Fib_alpha PF08702.10 GAP92622.1 - 0.094 12.9 4.3 0.18 12.0 4.3 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MPS2 PF17060.5 GAP92622.1 - 0.13 11.5 4.9 0.16 11.2 4.9 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 HEPN_Toprim_N PF18871.1 GAP92622.1 - 0.37 10.7 4.7 6.5 6.6 5.3 2.1 2 0 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 GAS PF13851.6 GAP92622.1 - 0.49 9.7 13.5 0.71 9.2 10.5 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 GAP92622.1 - 1.5 8.6 7.5 2 8.2 4.1 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.9 GAP92622.1 - 2.5 8.1 15.2 0.73 9.8 10.5 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SOAR PF16533.5 GAP92622.1 - 9.5 6.3 10.4 1.2 9.2 1.0 2.8 1 1 1 3 3 3 0 STIM1 Orai1-activating region p450 PF00067.22 GAP92623.1 - 4.2e-61 207.1 0.0 1.5e-49 169.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DLP_helical PF18709.1 GAP92623.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain HNH_2 PF13391.6 GAP92624.1 - 5.1e-09 36.1 1.3 1e-08 35.1 1.3 1.5 1 0 0 1 1 1 1 HNH endonuclease NOA36 PF06524.12 GAP92624.1 - 4.4 6.5 11.5 6.3 6.0 11.5 1.2 1 0 0 1 1 1 0 NOA36 protein Ank_4 PF13637.6 GAP92625.1 - 6.2e-68 224.4 21.6 7.1e-10 39.2 0.2 15.1 7 3 8 15 15 15 13 Ankyrin repeats (many copies) Ank_2 PF12796.7 GAP92625.1 - 8.7e-65 215.3 11.1 1.9e-11 44.4 0.2 9.9 6 1 3 9 9 9 7 Ankyrin repeats (3 copies) Ank PF00023.30 GAP92625.1 - 3.4e-52 172.7 29.3 0.0017 18.7 0.1 18.1 18 0 0 18 18 18 12 Ankyrin repeat Ank_3 PF13606.6 GAP92625.1 - 9.5e-49 157.7 27.8 0.0011 19.2 0.1 19.5 19 1 0 19 19 19 8 Ankyrin repeat NACHT_N PF17100.5 GAP92625.1 - 7.4e-34 117.5 1.4 1.3e-33 116.8 1.4 1.3 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_5 PF13857.6 GAP92625.1 - 3.5e-30 103.7 20.6 4.9e-08 33.1 0.6 12.8 9 5 5 15 15 14 6 Ankyrin repeats (many copies) NACHT PF05729.12 GAP92625.1 - 2.2e-12 47.2 0.0 5.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP92625.1 - 0.0015 19.0 0.0 0.0047 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 GAP92625.1 - 0.0021 18.4 0.1 0.0059 17.0 0.0 1.8 2 0 0 2 2 1 1 RNA helicase NB-ARC PF00931.22 GAP92625.1 - 0.0054 16.0 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 GAP92625.1 - 0.017 15.4 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 GAP92625.1 - 0.028 14.8 0.1 0.078 13.4 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 GAP92625.1 - 0.03 14.2 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RVP PF00077.20 GAP92625.1 - 0.81 10.0 2.3 2.3e+02 2.2 0.0 5.2 8 0 0 8 8 7 0 Retroviral aspartyl protease Glyco_hydro_18 PF00704.28 GAP92627.1 - 2.4e-64 218.0 0.0 3.1e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 GAP92627.1 - 0.0015 19.0 8.3 0.0015 19.0 8.3 4.0 4 0 0 4 4 4 2 Chitin recognition protein Clr5 PF14420.6 GAP92628.1 - 3.3e-21 75.2 0.5 9e-21 73.9 0.5 1.8 1 0 0 1 1 1 1 Clr5 domain CLP_protease PF00574.23 GAP92629.1 - 1.5e-73 246.6 0.0 1.9e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 GAP92629.1 - 0.0064 15.5 0.1 0.053 12.5 0.0 1.9 2 0 0 2 2 2 1 Serine dehydrogenase proteinase Abhydrolase_8 PF06259.12 GAP92629.1 - 0.14 11.8 0.1 0.29 10.7 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase Metallophos PF00149.28 GAP92632.1 - 9.3e-11 42.6 0.0 2.9e-10 41.0 0.0 1.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 GAP92632.1 - 3e-07 30.8 0.0 0.0011 19.2 0.0 2.6 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.31 GAP92634.1 - 3.7e-19 68.6 1.1 9.1e-19 67.4 1.1 1.8 1 0 0 1 1 1 1 DnaJ domain MBOAT PF03062.19 GAP92635.1 - 3.8e-43 148.2 11.7 2.4e-41 142.3 6.9 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Flavin_Reduct PF01613.18 GAP92636.1 - 8.4e-20 71.4 0.7 3.9e-19 69.2 0.7 2.0 1 1 0 1 1 1 1 Flavin reductase like domain Ank_2 PF12796.7 GAP92637.1 - 2.4e-29 101.7 0.1 7.6e-12 45.7 0.1 5.9 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP92637.1 - 2.4e-20 72.3 2.7 1.1e-09 38.4 0.1 7.1 5 1 3 8 8 8 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAP92637.1 - 4.6e-16 59.0 4.0 1e-07 32.3 0.1 7.3 4 3 4 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP92637.1 - 9.1e-14 50.2 2.2 0.017 15.6 0.0 8.6 9 1 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 GAP92637.1 - 7.3e-12 45.2 9.6 0.0082 16.6 0.1 7.0 7 0 0 7 7 7 3 Ankyrin repeat NACHT PF05729.12 GAP92637.1 - 9.4e-06 25.6 0.0 2.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAP92637.1 - 0.041 14.2 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF285 PF03382.14 GAP92637.1 - 0.12 12.2 0.8 0.44 10.3 0.4 2.1 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 DUF445 PF04286.12 GAP92637.1 - 1.7 8.4 5.0 0.63 9.8 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Dicty_REP PF05086.12 GAP92638.1 - 0.083 10.9 0.8 0.099 10.6 0.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ribosomal_L31 PF01197.18 GAP92638.1 - 0.09 13.0 0.5 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L31 IMUP PF15761.5 GAP92638.1 - 1.7 9.4 12.4 2.1 9.0 11.3 1.7 1 1 1 2 2 2 0 Immortalisation up-regulated protein DUF5423 PF17461.2 GAP92638.1 - 2.4 6.9 9.1 4.1 6.2 9.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Vps5 PF09325.10 GAP92639.1 - 1.4e-88 296.5 9.1 1.4e-88 296.5 9.1 1.7 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 GAP92639.1 - 1e-24 86.7 0.1 2.3e-24 85.5 0.1 1.6 1 0 0 1 1 1 1 PX domain BAR_3 PF16746.5 GAP92639.1 - 0.001 18.8 10.0 0.0033 17.2 4.9 2.6 1 1 1 2 2 2 1 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 GAP92639.1 - 0.0015 18.0 1.8 0.027 13.9 1.8 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR_2 PF10455.9 GAP92639.1 - 0.057 12.6 6.3 0.37 9.9 6.5 2.1 2 1 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Arfaptin PF06456.13 GAP92639.1 - 0.088 12.4 4.2 0.83 9.2 0.1 2.2 1 1 1 2 2 2 0 Arfaptin-like domain FadA PF09403.10 GAP92639.1 - 0.16 12.4 0.2 0.16 12.4 0.2 4.1 4 1 0 4 4 4 0 Adhesion protein FadA HBM PF16591.5 GAP92639.1 - 1.5 8.2 13.1 1.4 8.3 5.7 2.6 1 1 1 2 2 2 0 Helical bimodular sensor domain DUF713 PF05218.14 GAP92639.1 - 1.6 8.4 9.9 0.25 11.1 1.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF713) AcylCoA_dehyd_C PF12186.8 GAP92639.1 - 2 8.5 5.0 1.9 8.6 1.1 2.5 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal Cortex-I_coil PF09304.10 GAP92639.1 - 3.3 8.0 9.6 2.8 8.2 4.8 2.7 2 1 0 2 2 2 0 Cortexillin I, coiled coil Med11 PF10280.9 GAP92640.1 - 8.9e-40 136.3 0.0 1.2e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.32 GAP92641.1 - 6.3e-43 143.9 22.9 1.1e-10 41.9 4.4 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 GAP92641.1 - 8.5e-36 123.0 0.0 1.3e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 GAP92641.1 - 5.3e-13 49.1 0.2 0.00087 19.5 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 GAP92641.1 - 1.3e-07 31.3 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 GAP92641.1 - 3.8e-05 23.6 0.0 0.046 13.6 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 GAP92641.1 - 0.091 12.0 0.0 8.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AsnC_trans_reg PF01037.21 GAP92641.1 - 0.098 12.6 0.0 0.36 10.8 0.0 2.0 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Nup160 PF11715.8 GAP92641.1 - 0.1 11.2 0.5 3.7 6.1 0.0 2.9 3 1 0 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 GAP92641.1 - 0.22 10.8 0.0 38 3.5 0.0 3.1 3 0 0 3 3 3 0 WD40-like domain Glyco_hydro_18 PF00704.28 GAP92642.1 - 9.7e-72 242.3 0.2 1.1e-71 242.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_61 PF03443.14 GAP92644.1 - 6.5e-55 186.3 0.0 7.9e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1155 PF06633.11 GAP92644.1 - 0.29 10.6 0.1 0.29 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) AATase PF07247.12 GAP92645.1 - 3.1e-07 29.3 0.0 0.0029 16.2 0.0 3.6 3 1 0 3 3 3 3 Alcohol acetyltransferase Condensation PF00668.20 GAP92645.1 - 0.00054 18.7 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 Condensation domain WES_acyltransf PF03007.16 GAP92645.1 - 0.012 15.4 0.6 0.039 13.7 0.1 2.2 2 1 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Aminotran_4 PF01063.19 GAP92646.1 - 1.4e-17 64.3 0.0 5e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 Amino-transferase class IV Thioredoxin PF00085.20 GAP92647.1 - 5.3e-23 81.0 0.0 6.5e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 GAP92647.1 - 4.9e-07 30.2 0.1 1.6e-06 28.5 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 GAP92647.1 - 1.4e-06 28.6 0.0 1.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 GAP92647.1 - 6.4e-05 22.4 0.0 6.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 GAP92647.1 - 0.00013 21.8 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 GAP92647.1 - 0.00015 21.5 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 GAP92647.1 - 0.00047 19.9 0.1 0.0015 18.3 0.2 1.6 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 GAP92647.1 - 0.0014 18.7 0.1 0.0021 18.2 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like DSBA PF01323.20 GAP92647.1 - 0.0056 16.5 1.7 2 8.2 0.1 2.2 1 1 1 2 2 2 2 DSBA-like thioredoxin domain TraF PF13728.6 GAP92647.1 - 0.022 14.6 0.1 0.036 13.9 0.1 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein Zn_clus PF00172.18 GAP92648.1 - 2e-10 40.6 10.4 3.9e-10 39.7 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP92648.1 - 3.2e-10 39.5 6.2 7.7e-10 38.2 6.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cutinase PF01083.22 GAP92649.1 - 1.7e-34 119.4 0.0 2e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 GAP92649.1 - 0.00086 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 GAP92649.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 GAP92649.1 - 0.095 12.5 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2235 PF09994.9 GAP92649.1 - 0.14 11.5 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2855 PF11017.8 GAP92650.1 - 5.4e-57 194.1 0.1 2.8e-28 99.7 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2855) GPP34 PF05719.11 GAP92650.1 - 0.043 13.8 0.1 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Kinesin PF00225.23 GAP92651.1 - 2.3e-82 276.6 0.0 6.2e-82 275.2 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAP92651.1 - 5.1e-46 156.3 0.0 1.4e-45 154.8 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 GAP92651.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Flg_hook PF02120.16 GAP92651.1 - 0.37 10.7 6.2 0.44 10.5 1.0 2.9 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Lebercilin PF15619.6 GAP92651.1 - 1.5 8.4 51.9 0.089 12.4 5.5 3.2 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 GAP92651.1 - 4.9 4.5 46.6 0.16 9.5 29.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 GAP92651.1 - 7.1 7.0 50.9 0.19 12.1 15.6 2.9 2 1 1 3 3 3 0 Fez1 CobU PF02283.16 GAP92652.1 - 1.2 8.7 2.8 1.8 8.1 2.8 1.3 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ABM PF03992.16 GAP92653.1 - 0.027 14.6 0.3 0.078 13.1 0.1 1.8 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase PUF PF00806.19 GAP92654.1 - 3.5e-13 48.4 0.1 0.039 13.7 0.0 6.9 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat Glyco_hydro_64 PF16483.5 GAP92655.1 - 8.1e-119 397.2 0.0 9.5e-119 397.0 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Kinesin PF00225.23 GAP92656.1 - 7.7e-81 271.6 0.0 1.1e-80 271.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 GAP92656.1 - 2.5e-21 76.2 0.0 4.6e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 GAP92656.1 - 0.00053 20.2 0.0 0.0016 18.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 GAP92656.1 - 0.0057 17.2 0.0 0.087 13.4 0.0 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.23 GAP92656.1 - 0.0085 15.9 0.0 3.7 7.6 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif DUF3701 PF12482.8 GAP92656.1 - 0.011 15.8 0.0 0.051 13.7 0.0 2.1 2 0 0 2 2 2 0 Phage integrase protein DUF4611 PF15387.6 GAP92656.1 - 5 7.4 8.0 4.8 7.5 4.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) ADH_N PF08240.12 GAP92659.1 - 1e-27 96.2 0.9 2e-27 95.2 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP92659.1 - 2.3e-14 53.5 0.0 3.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAP92659.1 - 2.7e-08 33.6 0.0 6.6e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 GAP92659.1 - 0.077 12.3 0.1 0.17 11.2 0.0 1.6 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 GAP92659.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Cu-oxidase PF00394.22 GAP92660.1 - 1.3e-35 122.8 0.0 1.2e-32 113.3 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAP92660.1 - 1e-28 99.7 0.1 1e-28 99.7 0.1 2.6 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAP92660.1 - 2.3e-20 72.7 10.8 9.5e-18 64.3 3.9 3.3 2 2 0 2 2 2 2 Multicopper oxidase Abhydrolase_1 PF00561.20 GAP92661.1 - 2.9e-15 56.6 0.3 4.8e-14 52.6 0.4 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 GAP92661.1 - 1e-10 42.6 14.9 4.1e-09 37.4 11.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP92661.1 - 1.2e-05 24.7 0.4 0.00043 19.6 0.4 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 GAP92661.1 - 0.1 12.2 0.0 0.22 11.0 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family EHN PF06441.12 GAP92661.1 - 0.16 12.4 1.6 0.39 11.1 0.1 2.4 3 1 0 3 3 3 0 Epoxide hydrolase N terminus His_Phos_1 PF00300.22 GAP92662.1 - 2.3e-13 50.3 0.0 9.6e-13 48.3 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NACHT PF05729.12 GAP92663.1 - 4.1e-08 33.3 0.6 1.6e-07 31.4 0.0 2.3 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 GAP92663.1 - 0.00037 20.9 2.4 0.0028 18.0 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 GAP92663.1 - 0.00082 19.7 0.0 0.0037 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain SesA PF17107.5 GAP92663.1 - 0.0039 17.4 0.3 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases RNA_helicase PF00910.22 GAP92663.1 - 0.015 15.6 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 GAP92663.1 - 0.018 14.8 0.1 0.06 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 GAP92663.1 - 0.025 14.3 0.2 0.075 12.8 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 GAP92663.1 - 0.04 14.4 0.3 3.7 8.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain AIP3 PF03915.13 GAP92663.1 - 0.058 12.5 1.1 0.096 11.8 1.1 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 AAA_29 PF13555.6 GAP92663.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 GAP92663.1 - 0.088 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 GAP92663.1 - 0.09 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF2400 PF09674.10 GAP92663.1 - 0.11 12.5 0.9 0.25 11.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) AAA_18 PF13238.6 GAP92663.1 - 0.13 12.8 0.0 0.51 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mig-14 PF07395.11 GAP92663.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Mig-14 AAA_33 PF13671.6 GAP92663.1 - 0.46 10.6 1.7 2.2 8.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 GAP92665.1 - 3.1e-45 153.8 0.4 8.1e-45 152.5 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAP92665.1 - 6.3e-10 38.9 0.1 4e-09 36.3 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 GAP92665.1 - 6.6e-09 35.9 0.3 2.2e-08 34.2 0.1 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 GAP92665.1 - 4.7e-08 33.3 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 GAP92665.1 - 7.5e-08 32.9 0.1 3.7e-05 24.2 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 GAP92665.1 - 3.2e-06 26.5 0.0 6.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 GAP92665.1 - 4.1e-05 23.9 1.2 0.0088 16.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 GAP92665.1 - 0.00025 20.8 0.0 0.00069 19.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 GAP92665.1 - 0.00037 20.2 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_7 PF12775.7 GAP92665.1 - 0.00044 19.8 0.0 0.0026 17.3 0.1 2.1 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 GAP92665.1 - 0.00044 20.8 0.0 0.0015 19.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 GAP92665.1 - 0.00073 19.8 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 GAP92665.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 GAP92665.1 - 0.0014 18.6 0.0 0.019 15.0 0.0 2.1 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 GAP92665.1 - 0.0014 18.6 0.1 0.0055 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 GAP92665.1 - 0.0018 18.7 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 GAP92665.1 - 0.0032 17.4 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 GAP92665.1 - 0.0054 16.5 0.1 0.014 15.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 GAP92665.1 - 0.0056 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 GAP92665.1 - 0.006 16.5 0.2 0.11 12.4 0.0 2.7 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 GAP92665.1 - 0.0081 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 GAP92665.1 - 0.0088 16.2 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 GAP92665.1 - 0.01 15.3 0.0 0.5 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 GAP92665.1 - 0.011 15.4 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 GAP92665.1 - 0.022 14.7 0.6 0.33 10.8 0.0 2.7 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 GAP92665.1 - 0.024 14.4 0.2 0.055 13.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 GAP92665.1 - 0.042 13.2 1.1 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.18 GAP92665.1 - 0.043 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_11 PF13086.6 GAP92665.1 - 0.048 13.4 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAP92665.1 - 0.077 12.7 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 GAP92665.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 GAP92665.1 - 0.09 12.0 0.1 0.22 10.8 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin AAA_19 PF13245.6 GAP92665.1 - 0.12 12.7 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAP92665.1 - 0.13 11.8 1.7 0.27 10.8 0.1 2.1 2 1 1 3 3 3 0 AAA domain cobW PF02492.19 GAP92665.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 GAP92665.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 GAP92665.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Methyltransf_16 PF10294.9 GAP92667.1 - 2e-31 109.0 0.0 6.7e-31 107.3 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 GAP92667.1 - 0.00016 21.6 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP92667.1 - 0.22 11.1 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Mis14 PF08641.12 GAP92668.1 - 2e-14 54.0 0.8 3.4e-13 50.1 0.0 2.8 3 1 0 3 3 3 1 Kinetochore protein Mis14 like CRAL_TRIO PF00650.20 GAP92669.1 - 6.8e-32 110.4 0.0 1.1e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 GAP92669.1 - 3.5e-09 36.7 0.5 1.1e-08 35.1 0.2 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 GAP92669.1 - 0.0012 19.0 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Prefoldin PF02996.17 GAP92670.1 - 2.1e-33 114.8 0.0 2.9e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 GAP92670.1 - 0.0012 18.8 0.9 0.015 15.2 0.0 2.4 3 0 0 3 3 3 1 Prefoldin subunit HET PF06985.11 GAP92671.1 - 2.2e-08 34.6 1.7 7e-05 23.2 0.2 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.17 GAP92672.1 - 1.5e-17 63.8 0.0 5.7e-17 61.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAP92672.1 - 3.3e-16 59.5 0.0 3.9e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain FRQ PF09421.10 GAP92673.1 - 2.9e-266 886.3 69.0 1.1e-264 881.1 69.0 2.3 1 1 0 1 1 1 1 Frequency clock protein Nexin_C PF08628.12 GAP92673.1 - 0.19 12.3 0.3 0.91 10.1 0.0 2.2 2 0 0 2 2 2 0 Sorting nexin C terminal Glyco_hydro_125 PF06824.11 GAP92674.1 - 8.1e-150 499.3 0.0 2.9e-117 392.1 0.0 2.0 1 1 1 2 2 2 2 Metal-independent alpha-mannosidase (GH125) DUF2434 PF10361.9 GAP92675.1 - 1.7e-126 421.2 8.1 2.2e-126 420.8 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Polysacc_deac_1 PF01522.21 GAP92676.1 - 8.5e-27 93.5 0.0 1.2e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 GAP92676.1 - 0.0053 16.0 0.0 0.0069 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Amidoligase_2 PF12224.8 GAP92677.1 - 3.1e-19 69.6 0.0 1.3e-14 54.5 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme DEAD PF00270.29 GAP92678.1 - 5.7e-45 153.2 0.0 4.8e-43 147.0 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP92678.1 - 2.7e-20 72.8 0.0 1.6e-19 70.3 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP92678.1 - 1.4e-06 28.4 0.0 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Tannase PF07519.11 GAP92679.1 - 3.8e-94 316.2 0.0 4.4e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 GAP92679.1 - 0.084 12.1 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lycopene_cycl PF05834.12 GAP92680.1 - 0.086 11.9 0.2 0.11 11.5 0.2 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein PlyB_C PF18684.1 GAP92682.1 - 0.068 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Pleurotolysin B C-terminal domain zf-MYND PF01753.18 GAP92684.1 - 7.7e-08 32.3 11.2 3.1e-07 30.4 11.2 2.1 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 GAP92684.1 - 0.39 11.1 8.6 1 9.7 8.6 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding LpqV PF17301.2 GAP92685.1 - 0.67 10.2 10.5 11 6.3 7.9 2.3 2 0 0 2 2 2 0 Putative lipoprotein LpqV Glyco_transf_90 PF05686.12 GAP92686.1 - 1.3e-17 63.8 0.0 1.1e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 G-patch_2 PF12656.7 GAP92687.1 - 0.078 13.1 0.3 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 G-patch domain Clr5 PF14420.6 GAP92688.1 - 4.2e-14 52.5 0.3 1.3e-13 51.0 0.1 2.0 2 0 0 2 2 2 1 Clr5 domain Amidohydro_1 PF01979.20 GAP92689.1 - 1.2e-17 64.2 0.0 3.7e-16 59.4 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 GAP92689.1 - 2.5e-10 40.5 2.3 7.9e-06 25.6 0.2 2.5 2 1 0 2 2 2 2 Amidohydrolase family Serglycin PF04360.12 GAP92689.1 - 0.023 14.6 5.4 0.08 12.9 5.6 1.7 2 0 0 2 2 2 0 Serglycin Cyto_heme_lyase PF01265.17 GAP92690.1 - 6.7e-122 406.6 0.6 7.8e-122 406.4 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase FA_desaturase PF00487.24 GAP92691.1 - 4.5e-31 108.6 22.3 7.2e-31 107.9 22.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 GAP92691.1 - 4.2e-09 36.4 0.0 8.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC1 PF03109.16 GAP92692.1 - 8.8e-22 77.5 0.0 4.8e-13 49.3 0.0 2.5 1 1 1 2 2 2 2 ABC1 family APH PF01636.23 GAP92692.1 - 0.0031 17.5 0.1 0.012 15.5 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family POTRA_TamA_1 PF17243.2 GAP92692.1 - 0.12 12.5 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 POTRA domain TamA domain 1 FlxA PF14282.6 GAP92694.1 - 0.085 12.9 0.3 0.12 12.3 0.3 1.2 1 0 0 1 1 1 0 FlxA-like protein HMW1C_N PF18071.1 GAP92694.1 - 0.18 11.6 0.1 0.25 11.1 0.1 1.2 1 0 0 1 1 1 0 HMW1C N-terminal Cellulase PF00150.18 GAP92695.1 - 1e-19 71.1 6.1 1.3e-19 70.7 6.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Apis_Csd PF11671.8 GAP92695.1 - 0.22 11.5 3.8 0.064 13.3 0.8 1.6 2 0 0 2 2 2 0 Complementary sex determiner protein GST_C PF00043.25 GAP92697.1 - 2.5e-07 30.8 0.0 3.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAP92697.1 - 1.3e-06 28.7 0.0 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAP92697.1 - 2.7e-06 27.6 0.0 6.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAP92697.1 - 6.5e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAP92697.1 - 0.0001 22.5 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP92697.1 - 0.0014 18.6 0.1 0.0024 17.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.22 GAP92700.1 - 1.4e-23 83.4 0.0 2.6e-23 82.5 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 NACHT PF05729.12 GAP92702.1 - 3.3e-07 30.4 0.0 7.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP92702.1 - 4.6e-06 27.1 0.0 2.8e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 GAP92702.1 - 0.00017 20.9 0.0 0.00063 19.0 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 GAP92702.1 - 0.00018 21.8 0.0 0.00067 19.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAP92702.1 - 0.005 16.8 0.0 0.041 13.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAP92702.1 - 0.019 15.5 0.0 2.3 8.8 0.0 3.1 2 0 0 2 2 2 0 AAA domain Tnp_DNA_bind PF14706.6 GAP92702.1 - 0.094 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Transposase DNA-binding RNA_helicase PF00910.22 GAP92702.1 - 0.097 13.1 0.0 0.31 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase 7TM_GPCR_Srj PF10319.9 GAP92702.1 - 0.11 11.8 0.4 0.2 11.0 0.4 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srj CorA PF01544.18 GAP92702.1 - 1.7 7.9 5.1 1.8 7.8 1.0 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SNF2_N PF00176.23 GAP92703.1 - 5.6e-59 199.6 0.0 8.3e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP92703.1 - 2.9e-12 46.9 0.0 7.7e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP92703.1 - 7.7e-07 29.3 0.0 1.7e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 GAP92703.1 - 0.011 15.4 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 SWI2/SNF2 ATPase zf-RING_5 PF14634.6 GAP92703.1 - 1.5 8.8 4.4 3.6 7.6 4.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.25 GAP92704.1 - 5.7e-48 163.6 0.0 8.2e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92704.1 - 1.2e-28 100.1 0.0 2.1e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RicinB_lectin_2 PF14200.6 GAP92704.1 - 2.5e-07 31.3 0.2 6.7e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Kinase-like PF14531.6 GAP92704.1 - 0.0042 16.4 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 GAP92704.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Macscav_rec PF03523.13 GAP92706.1 - 0.24 11.3 0.7 0.93 9.4 0.0 2.3 2 0 0 2 2 2 0 Macrophage scavenger receptor PrsW-protease PF13367.6 GAP92707.1 - 0.062 12.7 0.3 0.19 11.1 0.3 1.8 1 0 0 1 1 1 0 PrsW family intramembrane metalloprotease DUF2534 PF10749.9 GAP92708.1 - 1.5 9.1 8.3 0.29 11.3 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2534) MFS_1 PF07690.16 GAP92710.1 - 3.8e-30 105.0 20.7 3.8e-30 105.0 20.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TauD PF02668.16 GAP92711.1 - 2.7e-14 53.6 0.0 3.2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_31 PF01055.26 GAP92712.1 - 1e-141 473.2 5.7 1.5e-141 472.6 5.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 GAP92712.1 - 1.8e-23 82.6 0.3 1.3e-22 79.9 0.1 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 GAP92712.1 - 1.5e-06 28.3 0.9 6e-06 26.4 0.9 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NDK PF00334.19 GAP92713.1 - 3.6e-53 179.2 0.0 4.5e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.9 GAP92714.1 - 1.7e-20 73.2 0.0 3.5e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Melibiase_2 PF16499.5 GAP92717.1 - 3.4e-61 206.9 4.2 5.4e-41 140.6 1.5 2.2 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 GAP92717.1 - 1.2e-11 44.6 0.2 2.5e-10 40.3 0.0 2.5 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 GAP92717.1 - 1.3e-07 31.0 0.0 2.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Melibiase Sensor PF13796.6 GAP92718.1 - 0.1 12.6 3.6 0.18 11.9 0.4 2.2 1 1 1 2 2 2 0 Putative sensor PAC4 PF16093.5 GAP92719.1 - 2e-24 85.6 0.0 2.9e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 N2227 PF07942.12 GAP92720.1 - 7.7e-93 310.6 0.0 1.1e-92 310.1 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 GAP92720.1 - 2e-05 25.1 0.0 0.00068 20.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP92720.1 - 0.00033 21.4 0.0 0.0026 18.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP92720.1 - 0.00088 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP92720.1 - 0.0039 17.9 0.0 0.079 13.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP92720.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain adh_short_C2 PF13561.6 GAP92721.1 - 8.7e-44 149.8 0.9 1.2e-43 149.4 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP92721.1 - 8.4e-41 139.6 1.0 9.2e-41 139.4 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAP92721.1 - 1.7e-09 37.9 0.3 2.8e-09 37.1 0.3 1.3 1 0 0 1 1 1 1 KR domain malic PF00390.19 GAP92721.1 - 0.19 11.5 0.0 3 7.6 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain Tau95 PF09734.9 GAP92722.1 - 9.7e-35 120.4 0.1 1.7e-34 119.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 GAP92722.1 - 1.2e-31 109.5 0.0 2.5e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain B56 PF01603.20 GAP92723.1 - 6.9e-191 634.7 4.6 8.1e-191 634.4 4.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 GAP92723.1 - 0.00071 19.5 1.4 0.3 11.0 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal PS_Dcarbxylase PF02666.15 GAP92724.1 - 2.2e-76 255.9 0.0 3.5e-75 252.0 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ubiquitin PF00240.23 GAP92725.1 - 4.8e-06 26.2 0.4 1.6e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 GAP92725.1 - 0.0002 21.8 0.1 0.0002 21.8 0.1 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Presenilin PF01080.17 GAP92725.1 - 1.1 8.0 6.4 4.1 6.1 0.1 2.2 2 0 0 2 2 2 0 Presenilin SelP_N PF04592.14 GAP92725.1 - 2.8 7.3 22.0 1.1 8.6 14.2 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region UvdE PF03851.14 GAP92726.1 - 0.048 12.9 0.1 0.096 11.9 0.1 1.4 1 0 0 1 1 1 0 UV-endonuclease UvdE Mito_fiss_reg PF05308.11 GAP92726.1 - 0.094 12.8 0.8 0.17 11.9 0.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Longin PF13774.6 GAP92727.1 - 2.3e-26 91.6 0.2 3.8e-26 90.9 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 GAP92727.1 - 6.3e-17 61.1 0.6 9.8e-17 60.5 0.1 1.6 2 0 0 2 2 2 1 Synaptobrevin DUF5435 PF17503.2 GAP92727.1 - 0.0043 16.8 0.0 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5435) DUF4404 PF14357.6 GAP92727.1 - 0.45 11.2 2.2 13 6.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) EMP24_GP25L PF01105.24 GAP92727.1 - 0.66 9.9 2.6 7.2 6.5 0.1 2.3 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.12 GAP92727.1 - 0.99 9.5 3.0 3.2 7.8 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ASXH PF13919.6 GAP92728.1 - 2.7e-32 111.7 0.3 4.6e-32 110.9 0.3 1.3 1 0 0 1 1 1 1 Asx homology domain Pap_E4 PF02711.14 GAP92728.1 - 0.38 11.8 8.4 42 5.2 0.1 3.9 3 0 0 3 3 3 0 E4 protein TRAPPC9-Trs120 PF08626.11 GAP92729.1 - 0 1416.7 0.0 0 1416.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ASH PF15780.5 GAP92729.1 - 0.058 13.6 0.1 0.57 10.4 0.0 2.7 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin adh_short PF00106.25 GAP92730.1 - 1.4e-21 76.9 0.0 2.2e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP92730.1 - 2.5e-17 63.2 0.0 3.8e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 GAP92730.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) KR PF08659.10 GAP92730.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 KR domain DUF2264 PF10022.9 GAP92731.1 - 4.3e-135 450.4 0.1 5.2e-135 450.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) AMP-binding PF00501.28 GAP92732.1 - 1.2e-40 139.5 0.0 1.7e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 GAP92732.1 - 9e-05 22.3 0.1 0.00021 21.1 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Fzo_mitofusin PF04799.13 GAP92733.1 - 0.93 9.0 6.5 0.18 11.3 0.7 2.0 2 0 0 2 2 2 0 fzo-like conserved region WD40 PF00400.32 GAP92734.1 - 2e-27 94.9 12.5 0.00036 21.3 0.0 7.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP92734.1 - 8.2e-07 29.2 2.8 0.2 12.0 0.1 5.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP92734.1 - 0.07 12.1 0.3 1.5 7.7 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Dynamin_M PF01031.20 GAP92735.1 - 1e-97 326.8 0.0 1.6e-97 326.2 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 GAP92735.1 - 8.6e-56 188.6 0.0 1.5e-55 187.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 GAP92735.1 - 6.4e-30 103.1 3.8 8.3e-30 102.8 1.4 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAP92735.1 - 1.7e-05 24.9 0.3 0.00015 21.8 0.3 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 GAP92735.1 - 0.053 13.2 0.6 2.3 7.8 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF2738 PF10927.8 GAP92735.1 - 0.053 12.6 0.0 0.18 10.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2738) CoA_transf_3 PF02515.17 GAP92736.1 - 1e-68 232.1 0.0 1.5e-68 231.6 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III UPF0029 PF01205.19 GAP92736.1 - 6.2e-33 113.3 0.0 9.9e-33 112.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 PPP5 PF08321.12 GAP92737.1 - 1.9e-33 114.6 1.2 1.3e-32 111.9 0.2 2.3 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 GAP92737.1 - 7.8e-33 114.7 0.1 1.2e-32 114.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 GAP92737.1 - 1.4e-20 72.2 0.8 7.3e-07 28.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAP92737.1 - 7.8e-15 53.7 0.4 4.7e-05 23.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 GAP92737.1 - 4.2e-11 42.4 0.6 0.014 15.8 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAP92737.1 - 5.1e-11 42.1 1.9 0.00065 19.3 0.1 3.5 3 0 0 3 3 3 3 TPR repeat TPR_8 PF13181.6 GAP92737.1 - 1.9e-07 30.8 0.3 0.011 15.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAP92737.1 - 4.5e-05 23.9 0.1 0.023 15.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 GAP92737.1 - 0.00028 21.0 0.0 0.029 14.5 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAP92737.1 - 0.00032 21.3 0.6 1.3 10.0 0.0 3.8 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAP92737.1 - 0.00051 20.6 0.2 1.3 9.8 0.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 GAP92737.1 - 0.0024 18.4 0.1 0.15 12.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 GAP92737.1 - 0.0089 15.5 0.1 0.74 9.3 0.0 2.9 3 0 0 3 3 3 1 SHNi-TPR Spt4 PF06093.13 GAP92738.1 - 1.7e-31 108.2 0.2 2e-31 107.9 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Spt20 PF12090.8 GAP92739.1 - 0.0031 17.1 12.9 0.0031 17.1 12.9 3.2 3 0 0 3 3 3 2 Spt20 family BAF1_ABF1 PF04684.13 GAP92739.1 - 2.6 7.0 27.2 0.069 12.2 4.8 3.1 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor CAF1C_H4-bd PF12265.8 GAP92740.1 - 2e-26 92.0 0.2 2.1e-25 88.7 0.1 2.7 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 GAP92740.1 - 2.2e-24 85.3 10.5 8.6e-06 26.4 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP92740.1 - 1.9e-06 28.1 0.2 0.017 15.4 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PhoLip_ATPase_C PF16212.5 GAP92741.1 - 1.4e-51 175.7 7.0 1.4e-51 175.7 7.0 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 GAP92741.1 - 4e-16 58.4 1.2 1.1e-15 57.0 1.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 GAP92741.1 - 1.9e-14 54.4 1.2 3.5e-08 34.0 0.4 3.3 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 GAP92741.1 - 9.4e-08 31.8 4.3 0.00045 19.8 0.1 2.8 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 GAP92741.1 - 1.6e-05 24.9 0.0 0.00029 20.8 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 GAP92741.1 - 0.0027 17.5 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AA_permease_C PF13906.6 GAP92741.1 - 3.3 7.9 9.6 1.4 9.1 5.5 2.5 2 0 0 2 2 2 0 C-terminus of AA_permease Ribonuc_L-PSP PF01042.21 GAP92742.1 - 1e-38 132.1 0.0 1.1e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP CCDC53 PF10152.9 GAP92743.1 - 0.2 12.1 1.1 0.3 11.5 1.1 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex LETM1 PF07766.13 GAP92744.1 - 5.5e-05 22.6 0.0 6.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 LETM1-like protein RRM_1 PF00076.22 GAP92745.1 - 6.7e-10 38.6 0.1 7.2e-09 35.3 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAP92745.1 - 5e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.20 GAP92746.1 - 7.2e-16 58.2 4.5 9.7e-16 57.8 4.5 1.3 1 0 0 1 1 1 1 RF-1 domain CHAD PF05235.14 GAP92746.1 - 0.033 14.2 4.6 0.045 13.7 4.6 1.2 1 1 0 1 1 1 0 CHAD domain VIT1 PF01988.19 GAP92746.1 - 0.077 12.9 1.7 0.11 12.4 1.7 1.2 1 0 0 1 1 1 0 VIT family Pkinase PF00069.25 GAP92747.1 - 1.5e-71 240.8 0.0 1.9e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92747.1 - 2.9e-29 102.1 0.0 4e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 GAP92747.1 - 4.4e-07 29.5 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 GAP92747.1 - 0.00011 21.1 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 GAP92747.1 - 0.00025 20.5 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 GAP92747.1 - 0.00046 20.2 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family SnoaL PF07366.12 GAP92748.1 - 0.00061 19.6 0.1 0.0011 18.8 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase 2-Hacid_dh_C PF02826.19 GAP92750.1 - 1.8e-49 167.5 0.1 2.4e-49 167.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 GAP92750.1 - 2.1e-16 59.8 0.0 3.2e-16 59.2 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 GAP92750.1 - 0.0044 17.2 0.2 0.0072 16.5 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 GAP92750.1 - 0.011 16.3 0.3 0.022 15.3 0.3 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 GAP92750.1 - 0.13 12.9 0.2 0.28 11.8 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RNA_polI_A34 PF08208.11 GAP92751.1 - 1.1e-33 117.1 12.0 1.1e-33 117.1 12.0 4.0 2 2 0 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 FAD_binding_3 PF01494.19 GAP92752.1 - 3.2e-86 289.7 0.0 4.7e-86 289.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 GAP92752.1 - 9.6e-52 175.4 0.0 1.7e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain CLP1_P PF16575.5 GAP92752.1 - 1.1e-27 97.0 0.0 1.9e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop HI0933_like PF03486.14 GAP92752.1 - 0.0023 16.7 0.1 0.0035 16.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 GAP92752.1 - 0.0031 17.1 0.1 0.0094 15.6 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP92752.1 - 0.0037 17.5 0.1 0.0095 16.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAP92752.1 - 0.0047 16.2 0.1 0.13 11.4 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 GAP92752.1 - 0.0053 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAP92752.1 - 0.011 14.9 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 GAP92752.1 - 0.011 15.0 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP92752.1 - 0.038 13.1 0.2 0.062 12.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 GAP92752.1 - 0.089 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 GAP92752.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Ig_mannosidase PF17753.1 GAP92753.1 - 1.3e-22 79.3 0.4 3.6e-22 77.9 0.2 1.9 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 GAP92753.1 - 1.7e-07 31.7 0.2 1.9e-06 28.4 0.2 2.8 1 1 0 1 1 1 1 Mannosidase Ig/CBM-like domain DUF4217 PF13959.6 GAP92753.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) DUF4185 PF13810.6 GAP92754.1 - 3.6e-11 42.9 5.0 3.6e-11 42.9 5.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4185) Peptidase_C12 PF01088.21 GAP92755.1 - 1.1e-39 136.4 0.0 1.3e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Annexin PF00191.20 GAP92756.1 - 2.3e-18 66.0 2.8 7.8e-05 22.7 0.1 4.4 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 GAP92756.1 - 0.14 12.6 0.4 5.4 7.6 0.1 3.2 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF2407_C PF13373.6 GAP92756.1 - 0.47 10.6 6.2 2.6 8.2 0.0 3.4 3 0 0 3 3 3 0 DUF2407 C-terminal domain DUF2828 PF11443.8 GAP92756.1 - 1.9 6.5 6.3 3.3 5.7 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) GPI2 PF06432.11 GAP92758.1 - 1.1e-132 441.7 0.1 1.3e-132 441.4 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase zf-C2H2 PF00096.26 GAP92759.1 - 1e-11 44.6 9.5 3e-05 24.2 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP92759.1 - 1.9e-08 34.4 8.9 9e-07 29.0 0.9 3.1 3 0 0 3 3 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP92759.1 - 5.3e-08 33.1 7.1 0.0012 19.5 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAP92759.1 - 0.00024 21.0 2.5 0.32 11.0 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP92759.1 - 0.0018 18.5 5.7 0.023 15.0 0.1 2.7 3 0 0 3 3 2 2 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 GAP92759.1 - 0.04 13.5 0.7 2.4 7.8 0.1 2.4 2 0 0 2 2 2 0 MYST family zinc finger domain zf-met PF12874.7 GAP92759.1 - 0.084 13.3 2.1 15 6.1 0.5 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type BolA PF01722.18 GAP92759.1 - 0.087 13.1 3.6 3.8 7.9 0.0 2.8 2 1 1 3 3 3 0 BolA-like protein DUF1635 PF07795.11 GAP92759.1 - 0.15 11.9 3.6 0.36 10.7 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) C5HCH PF17982.1 GAP92759.1 - 0.55 10.4 4.8 0.52 10.5 0.6 2.3 1 1 0 2 2 2 0 NSD Cys-His rich domain zf-C2HE PF16278.5 GAP92759.1 - 1.2 9.6 4.3 23 5.5 0.4 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 GAP92759.1 - 4.3 7.2 8.4 4.5 7.1 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-AN1 PF01428.16 GAP92759.1 - 8.8 6.6 7.1 38 4.6 1.1 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger Aspzincin_M35 PF14521.6 GAP92761.1 - 0.039 14.5 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Peptidase_Prp PF04327.12 GAP92761.1 - 0.044 14.0 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 Cysteine protease Prp Peptidase_M35 PF02102.15 GAP92761.1 - 0.27 10.1 0.0 0.4 9.5 0.0 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Ctr PF04145.15 GAP92762.1 - 1.6e-26 93.7 0.3 1.9e-26 93.4 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PAP2 PF01569.21 GAP92762.1 - 0.37 10.6 4.7 0.35 10.6 0.2 2.1 2 0 0 2 2 2 0 PAP2 superfamily SRF-TF PF00319.18 GAP92763.1 - 4.6e-21 74.0 0.1 6.3e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Tetraspanin PF00335.20 GAP92765.1 - 3.5e-05 23.6 4.7 6.2e-05 22.8 4.7 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF4191 PF13829.6 GAP92765.1 - 1.6 8.0 0.0 1.6 8.0 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) LRR_6 PF13516.6 GAP92767.1 - 9.2e-16 56.5 25.8 1.6 9.0 0.1 12.9 13 0 0 13 13 13 7 Leucine Rich repeat F-box-like PF12937.7 GAP92767.1 - 1.9e-13 50.1 1.4 1.9e-13 50.1 1.4 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 GAP92767.1 - 4.8e-12 45.9 17.0 0.12 12.8 0.2 7.4 6 1 1 7 7 7 5 Leucine Rich repeats (2 copies) F-box PF00646.33 GAP92767.1 - 0.00024 20.9 0.8 0.00084 19.2 0.8 2.1 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.11 GAP92767.1 - 0.043 13.5 0.5 1.5 8.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) PSDC PF12588.8 GAP92768.1 - 4e-40 137.0 0.0 1.5e-34 119.0 0.0 2.2 1 1 1 2 2 2 2 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 GAP92768.1 - 5.2e-33 114.3 0.0 7.7e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 GAP92768.1 - 0.074 12.9 1.2 1.8 8.4 0.5 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like Zn_clus PF00172.18 GAP92769.1 - 2.6e-05 24.2 13.4 5.4e-05 23.2 13.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 GAP92769.1 - 0.00053 19.1 0.0 0.00089 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 GAP92770.1 - 1.7e-91 307.4 23.4 1.9e-91 307.2 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP92770.1 - 1.4e-12 47.2 43.2 1e-06 27.9 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 GAP92772.1 - 3.9e-31 108.2 1.1 5.6e-17 61.6 0.0 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain DIOX_N PF14226.6 GAP92773.1 - 0.00016 22.4 0.0 0.00022 21.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal BAR PF03114.18 GAP92774.1 - 1.3e-47 162.4 7.7 1.7e-47 162.1 7.7 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 GAP92774.1 - 0.00039 19.7 1.1 0.00051 19.3 1.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Ribosomal_S10 PF00338.22 GAP92774.1 - 0.17 12.1 0.1 0.34 11.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e DUF2894 PF11445.8 GAP92774.1 - 0.37 11.2 4.2 0.095 13.2 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) OmpH PF03938.14 GAP92774.1 - 1 9.7 8.1 2.8 8.3 6.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Uds1 PF15456.6 GAP92774.1 - 1.5 9.0 9.0 0.45 10.7 6.0 1.7 2 0 0 2 2 2 0 Up-regulated During Septation 5_nucleotid_C PF02872.18 GAP92775.1 - 1.2e-35 123.1 0.5 2.5e-35 122.0 0.1 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 GAP92775.1 - 9.1e-12 45.9 0.2 2.2e-11 44.6 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 GAP92775.1 - 0.0059 16.0 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 YmdB-like protein PGA_cap PF09587.10 GAP92775.1 - 0.08 12.4 0.1 0.34 10.3 0.1 1.9 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Acyltransferase PF01553.21 GAP92776.1 - 3.1e-25 88.4 0.0 4.8e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 GAP92776.1 - 3.1e-14 52.8 0.2 5.5e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus LIDHydrolase PF10230.9 GAP92777.1 - 5.2e-49 167.2 0.0 2.3e-48 165.0 0.0 1.8 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 GAP92777.1 - 2.2e-05 25.2 10.9 3.1e-05 24.7 10.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 GAP92777.1 - 0.00069 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP92777.1 - 0.0052 16.1 0.0 0.021 14.1 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 GAP92777.1 - 0.057 13.5 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Glyco_hydro_72 PF03198.14 GAP92778.1 - 7.4e-121 403.2 0.6 9.6e-121 402.9 0.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 GAP92778.1 - 1e-21 77.4 3.7 1e-21 77.4 3.7 2.0 2 0 0 2 2 2 1 X8 domain Glyco_hydro_2_C PF02836.17 GAP92778.1 - 0.0025 17.0 0.0 0.012 14.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain TauD PF02668.16 GAP92779.1 - 1.3e-19 71.0 0.0 2e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 GAP92779.1 - 0.0078 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 CsiD CotJB PF12652.7 GAP92780.1 - 0.23 11.7 0.6 0.55 10.5 0.6 1.7 1 0 0 1 1 1 0 CotJB protein TPR_2 PF07719.17 GAP92781.1 - 1.3e-07 31.2 4.5 2.7e-05 23.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 GAP92781.1 - 4e-06 27.2 7.9 6.5e-06 26.5 1.7 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAP92781.1 - 6e-06 26.7 0.5 3.1e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP92781.1 - 9.8e-05 22.0 0.2 0.017 15.0 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 GAP92781.1 - 0.00042 20.9 0.2 0.00042 20.9 0.2 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 GAP92781.1 - 0.00043 20.3 0.0 0.014 15.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 GAP92781.1 - 0.00044 20.5 3.7 0.061 13.6 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAP92781.1 - 0.011 15.9 2.1 0.021 15.0 0.7 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 GAP92781.1 - 0.027 14.3 5.9 0.77 9.7 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat NpwBP PF12622.7 GAP92781.1 - 0.071 13.9 1.4 0.14 13.0 1.4 1.5 1 0 0 1 1 1 0 mRNA biogenesis factor TPR_4 PF07721.14 GAP92781.1 - 0.29 11.9 0.6 0.29 11.9 0.6 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ABATE PF07336.11 GAP92781.1 - 7.1 7.3 13.6 1.7 9.3 7.7 2.2 1 1 0 2 2 2 0 Putative stress-induced transcription regulator CFEM PF05730.11 GAP92784.1 - 7.4e-13 48.4 12.3 1.1e-12 47.9 12.3 1.2 1 0 0 1 1 1 1 CFEM domain PT PF04886.12 GAP92784.1 - 3.4e-12 45.7 86.1 81 2.9 4.3 4.4 2 1 0 2 2 2 0 PT repeat KAR9 PF08580.10 GAP92784.1 - 2.7 6.4 8.9 2.8 6.4 8.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF89 PF01937.19 GAP92785.1 - 3.9e-116 387.9 0.0 4.4e-116 387.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Promethin PF16015.5 GAP92786.1 - 1.5e-16 60.2 27.1 1.9e-16 59.9 27.1 1.1 1 0 0 1 1 1 1 Promethin UQ_con PF00179.26 GAP92788.1 - 3.2e-43 146.7 0.0 4.1e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 GAP92788.1 - 1.2e-06 28.2 0.1 2.1e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain SnAPC_2_like PF11035.8 GAP92788.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF1421 PF07223.11 GAP92788.1 - 0.17 11.8 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain (DUF1421) Radical_SAM_C PF16199.5 GAP92789.1 - 4.2e-32 110.0 0.0 8.4e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 GAP92789.1 - 1.2e-17 64.7 0.1 5.6e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 GAP92789.1 - 1.5e-10 41.3 0.1 2.7e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 GAP92789.1 - 3.8e-06 26.9 0.0 1.2e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP92789.1 - 0.021 15.2 0.1 0.047 14.1 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 GAP92790.1 - 3.5e-27 94.9 0.9 3.5e-27 94.9 0.9 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 GAP92790.1 - 7.5e-24 84.3 0.3 1.2e-23 83.6 0.3 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 GAP92790.1 - 1.1e-08 35.0 0.1 2e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 GAP92790.1 - 0.00038 20.9 0.0 0.0016 19.0 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain AAA PF00004.29 GAP92791.1 - 4.5e-41 140.4 0.0 7.7e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 GAP92791.1 - 1.2e-11 44.3 0.2 2.5e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 GAP92791.1 - 4.6e-11 42.3 0.6 8.3e-11 41.5 0.6 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 GAP92791.1 - 2.5e-06 27.7 0.0 4.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 GAP92791.1 - 5.6e-06 26.7 0.2 0.0058 16.9 0.2 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 GAP92791.1 - 1.2e-05 24.6 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 GAP92791.1 - 8.6e-05 22.6 0.1 0.00028 20.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 GAP92791.1 - 0.00023 21.6 0.2 0.008 16.6 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAP92791.1 - 0.00033 20.5 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 GAP92791.1 - 0.00079 20.0 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 GAP92791.1 - 0.00091 18.8 0.5 0.0056 16.3 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 GAP92791.1 - 0.0022 18.2 0.2 0.008 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 GAP92791.1 - 0.007 16.5 0.1 0.026 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAP92791.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 GAP92791.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 GAP92791.1 - 0.018 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 GAP92791.1 - 0.019 14.4 1.8 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 GAP92791.1 - 0.02 14.8 0.2 0.62 10.0 0.1 2.4 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 GAP92791.1 - 0.025 13.8 0.1 0.056 12.6 0.1 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 GAP92791.1 - 0.044 13.1 0.1 0.51 9.7 0.1 2.2 1 1 0 2 2 2 0 KaiC RNA_helicase PF00910.22 GAP92791.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 GAP92791.1 - 0.061 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 GAP92791.1 - 0.067 12.5 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 GAP92791.1 - 0.081 12.5 1.5 0.57 9.7 0.4 2.5 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 GAP92791.1 - 0.11 12.2 1.0 0.29 10.8 0.3 2.2 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAP92791.1 - 0.17 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ysc84 PF04366.12 GAP92792.1 - 3.3e-40 136.8 6.8 1.4e-39 134.7 6.8 2.0 1 1 0 1 1 1 1 Las17-binding protein actin regulator DUF2784 PF10861.8 GAP92792.1 - 0.15 12.1 0.4 0.24 11.4 0.4 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) HTH_ABP1_N PF18107.1 GAP92793.1 - 5.9e-24 83.5 3.9 5.9e-24 83.5 3.9 2.7 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 GAP92793.1 - 8.5e-15 54.5 0.2 8.5e-15 54.5 0.2 3.1 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DUF2722 PF10846.8 GAP92793.1 - 0.0058 15.6 13.7 0.0058 15.6 13.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) SUIM_assoc PF16619.5 GAP92793.1 - 0.016 15.3 19.0 1.9e+02 2.2 0.0 4.3 2 2 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RskA PF10099.9 GAP92793.1 - 0.076 13.3 13.2 0.22 11.8 5.7 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PAT1 PF09770.9 GAP92793.1 - 0.32 9.2 14.5 0.19 9.9 11.9 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.6 GAP92793.1 - 0.47 9.8 5.9 2.1 7.6 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3573 PF12097.8 GAP92793.1 - 0.62 8.8 4.6 0.81 8.5 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) EPL1 PF10513.9 GAP92793.1 - 0.63 10.4 9.8 0.3 11.5 6.9 1.9 2 0 0 2 2 2 0 Enhancer of polycomb-like Thymidylat_synt PF00303.19 GAP92794.1 - 4.5e-110 367.0 0.0 5.2e-110 366.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase SH3_1 PF00018.28 GAP92795.1 - 6.8e-28 96.0 0.0 1.8e-13 49.8 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 GAP92795.1 - 2.3e-20 72.2 0.1 3.4e-10 39.6 0.1 2.8 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 GAP92795.1 - 6.8e-14 51.8 0.0 1.5e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 GAP92795.1 - 4.8e-13 48.6 0.0 3.4e-08 33.1 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.24 GAP92795.1 - 3.5e-08 33.3 0.1 5.9e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 PB1 domain ubiquitin PF00240.23 GAP92795.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin family Rad60-SLD PF11976.8 GAP92795.1 - 0.88 9.4 4.4 0.25 11.2 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like HATPase_c_3 PF13589.6 GAP92796.1 - 0.032 14.1 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAC3_GANP PF03399.16 GAP92797.1 - 2.1e-24 86.4 6.7 2.4e-22 79.7 6.7 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 GAP92797.1 - 0.009 16.0 0.5 0.024 14.6 0.1 1.8 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family EAP30 PF04157.16 GAP92798.1 - 1e-43 149.4 0.1 1.4e-43 148.9 0.1 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 GAP92798.1 - 1.7e-21 76.2 0.0 2.8e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 GAP92798.1 - 7.8e-21 73.3 1.7 7.8e-21 73.3 1.7 2.8 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 GAP92798.1 - 0.00063 19.0 0.8 0.00063 19.0 0.8 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 GAP92798.1 - 0.0016 18.5 5.3 0.021 14.8 0.4 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger GRAM PF02893.20 GAP92798.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 GRAM domain DZR PF12773.7 GAP92798.1 - 4.8 7.3 9.2 0.32 11.1 0.7 2.8 3 1 0 3 3 3 0 Double zinc ribbon DUF3439 PF11921.8 GAP92799.1 - 0.029 14.3 9.6 0.062 13.3 9.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_S9 PF00326.21 GAP92800.1 - 2.2e-39 135.1 0.0 3.9e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 GAP92800.1 - 2.2e-06 26.6 0.0 0.00024 19.9 0.0 2.8 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) PD40 PF07676.12 GAP92800.1 - 0.0012 18.7 4.9 0.039 13.9 0.2 3.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Abhydrolase_2 PF02230.16 GAP92800.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAP92800.1 - 0.042 13.1 0.0 0.15 11.3 0.0 1.8 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DUF2920 PF11144.8 GAP92800.1 - 0.13 11.4 0.1 1.3 8.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) PLDc_2 PF13091.6 GAP92802.1 - 1.1e-20 73.9 0.0 8.6e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAP92802.1 - 0.017 15.3 0.4 7.6 6.9 0.1 2.6 2 0 0 2 2 2 0 Phospholipase D Active site motif Regulator_TrmB PF11495.8 GAP92802.1 - 0.047 12.9 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Peptidase_M28 PF04389.17 GAP92803.1 - 9.3e-27 94.0 0.0 1.5e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAP92803.1 - 6.5e-07 29.2 0.1 2e-06 27.7 0.1 1.8 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 DUF998 PF06197.13 GAP92805.1 - 0.026 14.1 7.6 0.14 11.8 1.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF998) Leader_Thr PF08254.11 GAP92805.1 - 0.2 11.4 3.1 0.4 10.5 3.1 1.5 1 0 0 1 1 1 0 Threonine leader peptide Aminotran_3 PF00202.21 GAP92806.1 - 5.4e-89 298.7 0.0 6.6e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 GAP92806.1 - 0.13 11.4 0.0 0.3 10.2 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II EGF_alliinase PF04863.13 GAP92806.1 - 1.2 9.6 4.6 0.4 11.1 0.8 2.2 3 0 0 3 3 3 0 Alliinase EGF-like domain Exo70 PF03081.15 GAP92807.1 - 3.8e-91 306.0 0.2 8.5e-90 301.5 0.0 2.2 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.12 GAP92807.1 - 0.00024 21.1 10.6 0.091 12.8 0.7 4.4 4 0 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus MukF_M PF17192.4 GAP92807.1 - 0.013 15.2 3.7 0.69 9.6 0.0 3.6 3 1 1 4 4 4 0 MukF middle domain EF-hand_11 PF08976.11 GAP92807.1 - 0.16 12.9 0.2 0.5 11.3 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain DUF3037 PF11236.8 GAP92807.1 - 0.21 12.0 1.1 3.6 8.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3037) Apolipoprotein PF01442.18 GAP92807.1 - 0.75 9.6 7.2 1.6 8.6 0.1 3.7 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain DUF2203 PF09969.9 GAP92807.1 - 1.5 9.6 9.1 0.18 12.5 0.4 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) Sec8_exocyst PF04048.14 GAP92807.1 - 1.7 8.5 8.6 2.6 7.9 0.1 4.2 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain PMEI PF04043.15 GAP92807.1 - 1.9 8.8 7.9 0.34 11.2 0.4 3.4 4 1 1 5 5 5 0 Plant invertase/pectin methylesterase inhibitor NPV_P10 PF05531.12 GAP92807.1 - 4.5 7.8 8.3 5.2 7.6 0.1 3.9 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Orf78 PF06024.12 GAP92808.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Herpes_gE PF02480.16 GAP92808.1 - 0.074 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FixQ PF05545.11 GAP92808.1 - 0.079 12.9 1.3 0.14 12.1 1.3 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ YajC PF02699.15 GAP92808.1 - 0.12 12.3 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Mucin PF01456.17 GAP92808.1 - 0.24 11.4 12.8 0.087 12.8 10.3 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein EVI2A PF05399.11 GAP92808.1 - 9.2 5.8 8.9 29 4.2 8.9 1.7 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) IBR PF01485.21 GAP92810.1 - 1.4e-13 50.8 43.1 6.5e-09 35.9 9.5 3.7 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 GAP92810.1 - 0.0025 17.6 1.5 0.0025 17.6 1.5 3.8 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) MCR PF18509.1 GAP92810.1 - 0.065 12.8 1.9 0.22 11.1 1.9 2.0 1 0 0 1 1 1 0 Magnetochrome domain DUF2158 PF09926.9 GAP92810.1 - 0.15 11.8 0.3 0.29 10.9 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) FAM176 PF14851.6 GAP92810.1 - 0.64 9.7 9.5 8 6.1 0.6 3.5 3 0 0 3 3 3 0 FAM176 family Filo_glycop PF01611.16 GAP92810.1 - 6.1 5.7 7.4 41 3.0 0.0 2.2 2 0 0 2 2 2 0 Filovirus glycoprotein DUF676 PF05057.14 GAP92811.1 - 3.5e-41 141.1 0.0 8.4e-32 110.5 0.0 3.2 1 1 1 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 GAP92811.1 - 0.025 15.2 0.0 0.069 13.7 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 GAP92811.1 - 0.025 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.11 GAP92811.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 GAP92811.1 - 0.11 12.3 0.0 0.38 10.6 0.0 1.8 1 1 1 2 2 2 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 GAP92811.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Bromodomain PF00439.25 GAP92812.1 - 3.4e-19 68.7 0.0 5.7e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 GAP92812.1 - 1.2e-05 25.5 0.0 4.8e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Carb_bind PF10645.9 GAP92813.1 - 3.5e-13 49.6 8.1 7.7e-13 48.4 8.1 1.6 1 0 0 1 1 1 1 Carbohydrate binding RecA PF00154.21 GAP92814.1 - 4.6e-06 26.3 0.0 1.4e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 GAP92814.1 - 5.5e-05 22.6 0.0 9.5e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.15 GAP92814.1 - 0.00018 20.9 0.0 0.0053 16.1 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 GAP92814.1 - 0.00076 19.3 0.1 0.0019 18.0 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 GAP92814.1 - 0.0018 17.9 0.0 0.0061 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Rad51 PF08423.11 GAP92814.1 - 0.0036 16.6 0.0 0.0097 15.2 0.0 1.7 2 1 0 2 2 2 1 Rad51 AAA_16 PF13191.6 GAP92814.1 - 0.032 14.6 0.0 0.081 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 GAP92814.1 - 0.035 13.8 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAP92814.1 - 0.043 13.7 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 GAP92814.1 - 0.057 13.6 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain GIDA PF01134.22 GAP92814.1 - 0.13 11.3 0.0 3.2 6.7 0.0 2.1 1 1 0 1 1 1 0 Glucose inhibited division protein A AAA PF00004.29 GAP92814.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 GAP92814.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein zf-H2C2_2 PF13465.6 GAP92815.1 - 4.8e-08 33.1 22.8 7.6e-05 23.0 3.4 4.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 GAP92815.1 - 9.8e-06 25.8 13.1 0.00045 20.5 4.5 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 GAP92815.1 - 0.037 14.7 1.7 0.17 12.5 0.1 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 GAP92815.1 - 0.051 14.4 3.1 0.051 14.4 3.1 3.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 GAP92815.1 - 0.053 13.8 0.4 0.053 13.8 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SNF2_N PF00176.23 GAP92816.1 - 3e-27 95.3 0.0 1.4e-26 93.1 0.0 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 GAP92816.1 - 7.9e-14 52.0 0.1 2.6e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 GAP92816.1 - 0.00018 21.4 4.4 0.00044 20.2 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger ERCC3_RAD25_C PF16203.5 GAP92816.1 - 0.00021 20.6 0.0 0.00044 19.6 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 GAP92816.1 - 0.00026 21.0 0.1 0.0046 17.0 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 GAP92816.1 - 0.00099 19.0 7.8 0.0024 17.8 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 GAP92816.1 - 0.0014 18.5 7.5 0.0014 18.4 6.0 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 GAP92816.1 - 0.004 17.0 4.9 0.0092 15.8 4.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 GAP92816.1 - 0.059 13.5 8.3 0.14 12.4 8.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 GAP92816.1 - 0.07 13.5 5.9 0.18 12.2 5.9 1.7 1 0 0 1 1 1 0 Ring finger domain DEAD PF00270.29 GAP92816.1 - 0.095 12.5 0.2 0.32 10.8 0.0 2.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase zf-MIZ PF02891.20 GAP92816.1 - 0.44 10.3 2.8 0.9 9.3 2.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zinc-ribbons_6 PF07191.12 GAP92816.1 - 0.8 9.7 8.4 1.7 8.7 8.4 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-RING_4 PF14570.6 GAP92816.1 - 1.6 8.6 7.3 3.7 7.4 7.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 GAP92816.1 - 2.4 8.4 6.4 9.5 6.4 6.4 2.0 1 1 0 1 1 1 0 FYVE zinc finger DZR PF12773.7 GAP92816.1 - 3.5 7.7 9.9 54 3.9 0.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 GAP92816.1 - 9.9 6.1 7.6 32 4.5 7.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AAT PF03417.16 GAP92817.1 - 1.5e-28 100.1 0.0 1.8e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase GST_N PF02798.20 GAP92818.1 - 4.3e-13 49.4 0.0 8.7e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 GAP92818.1 - 5.5e-13 49.1 0.1 9.4e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 GAP92818.1 - 2.6e-10 40.3 0.0 4.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 GAP92818.1 - 2.9e-10 40.3 0.1 8.7e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP92818.1 - 3.8e-09 36.6 0.0 6.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP92818.1 - 1.3e-07 31.5 0.0 2.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 GAP92818.1 - 0.00088 19.8 0.0 0.064 13.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAP92818.1 - 0.13 13.1 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain SPX PF03105.19 GAP92819.1 - 7.8e-41 141.3 4.6 2.4e-28 100.1 0.0 2.8 2 1 1 3 3 3 2 SPX domain Na_sulph_symp PF00939.19 GAP92819.1 - 7e-33 114.4 35.2 1.1e-32 113.7 35.2 1.4 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 GAP92819.1 - 1.4e-27 96.7 32.0 1.4e-27 96.7 32.0 2.1 2 1 0 2 2 2 1 Citrate transporter DUF4181 PF13789.6 GAP92819.1 - 0.41 10.9 4.0 19 5.6 4.0 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) PBP1_TM PF14812.6 GAP92819.1 - 6.7 7.2 9.4 0.51 10.7 2.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vps39_1 PF10366.9 GAP92820.1 - 4.8e-30 104.0 0.0 3e-29 101.5 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 GAP92820.1 - 1.5e-18 67.4 0.0 3.4e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 GAP92820.1 - 5.8e-12 46.0 0.0 1.6e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 GAP92820.1 - 0.0026 17.6 2.0 0.005 16.7 0.3 2.3 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.28 GAP92820.1 - 0.59 10.1 3.3 51 3.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Gon7 PF08738.10 GAP92821.1 - 6.5e-09 35.8 2.8 6.5e-09 35.8 2.8 2.5 1 1 1 3 3 3 1 Gon7 family CASP_C PF08172.12 GAP92821.1 - 0.022 14.1 1.6 0.03 13.7 1.6 1.2 1 0 0 1 1 1 0 CASP C terminal Peptidase_M28 PF04389.17 GAP92822.1 - 2.8e-36 125.1 0.0 4.7e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 GAP92822.1 - 5.5e-09 36.0 0.0 1.3e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 GAP92822.1 - 0.00018 21.1 0.9 0.00029 20.4 0.1 1.7 2 0 0 2 2 2 1 Nicastrin Peptidase_M42 PF05343.14 GAP92822.1 - 0.00033 19.8 0.0 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase HbrB PF08539.11 GAP92823.1 - 7.9e-52 175.7 0.0 7.9e-52 175.7 0.0 2.3 2 0 0 2 2 2 1 HbrB-like DUF4471 PF14740.6 GAP92823.1 - 0.0076 15.5 0.8 0.013 14.7 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) Spt20 PF12090.8 GAP92823.1 - 0.034 13.8 37.3 0.063 12.9 37.3 1.3 1 0 0 1 1 1 0 Spt20 family SpoIIP PF07454.11 GAP92823.1 - 0.071 12.6 9.9 0.16 11.4 9.9 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) X PF00739.19 GAP92823.1 - 0.11 12.6 0.4 14 5.8 0.0 3.3 2 0 0 2 2 2 0 Trans-activation protein X FAM176 PF14851.6 GAP92823.1 - 0.48 10.1 4.4 1.2 8.8 4.4 1.7 1 0 0 1 1 1 0 FAM176 family PepSY_TM PF03929.16 GAP92823.1 - 1.1 8.8 4.5 2.5 7.7 4.5 1.7 1 0 0 1 1 1 0 PepSY-associated TM region CobT PF06213.12 GAP92823.1 - 2.6 7.4 17.6 1.3 8.4 15.4 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT CLN3 PF02487.17 GAP92823.1 - 2.7 6.9 9.1 5.3 6.0 9.1 1.3 1 0 0 1 1 1 0 CLN3 protein Lin-8 PF03353.15 GAP92823.1 - 4 6.9 16.7 8.5 5.8 16.7 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SID-1_RNA_chan PF13965.6 GAP92823.1 - 4.9 5.4 5.0 6.7 5.0 5.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TERB2 PF15101.6 GAP92823.1 - 5 7.1 19.7 13 5.7 19.7 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Cupin_5 PF06172.11 GAP92824.1 - 7.1e-48 162.4 0.0 8.2e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) LIM_bind PF01803.16 GAP92825.1 - 1.3e-68 231.1 0.6 1.3e-68 231.1 0.6 6.4 3 1 2 5 5 5 1 LIM-domain binding protein Haem_degrading PF03928.14 GAP92826.1 - 5.4e-31 107.1 1.1 1.4e-30 105.8 1.1 1.6 1 1 0 1 1 1 1 Haem-degrading DAP10 PF07213.11 GAP92826.1 - 0.097 12.6 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Atg8 PF02991.16 GAP92827.1 - 2.7e-51 172.1 0.2 3.2e-51 171.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 GAP92827.1 - 3.1e-06 27.5 0.0 3.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coatomer_WDAD PF04053.14 GAP92829.1 - 0.33 10.0 0.0 0.5 9.3 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region PPTA PF01239.22 GAP92830.1 - 9.6e-33 111.0 21.7 1.2e-07 31.2 0.0 6.5 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat DUF3950 PF13132.6 GAP92830.1 - 0.11 12.3 0.1 4.2 7.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) Rxt3 PF08642.10 GAP92833.1 - 4e-44 150.4 0.0 1.3e-43 148.8 0.0 1.9 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 GAP92833.1 - 2.9e-07 30.5 0.0 7e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 LCCL domain SelP_N PF04592.14 GAP92833.1 - 0.72 9.2 12.7 2.4 7.5 12.7 1.8 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Trp_syntA PF00290.20 GAP92834.1 - 4.5e-96 320.7 0.3 8.2e-96 319.8 0.0 1.5 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 GAP92834.1 - 4.9e-47 160.7 1.0 4.9e-47 160.7 1.0 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L28 PF00830.19 GAP92836.1 - 1.2e-14 54.2 0.0 1.7e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L28 family Suf PF05843.14 GAP92837.1 - 0.025 14.6 3.8 0.037 14.0 3.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Aminotran_1_2 PF00155.21 GAP92838.1 - 5.9e-27 94.8 0.0 7.8e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PRIMA1 PF16101.5 GAP92840.1 - 0.00051 20.1 8.5 0.00051 20.1 8.5 3.7 1 1 3 4 4 4 1 Proline-rich membrane anchor 1 DUF4131 PF13567.6 GAP92840.1 - 0.12 12.0 0.2 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Herpes_gE PF02480.16 GAP92840.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 GAP92840.1 - 5.4 6.9 0.0 5.4 6.9 0.0 3.1 2 1 0 2 2 2 0 TMEM154 protein family HET PF06985.11 GAP92841.1 - 6.5e-09 36.3 1.9 8.3e-09 35.9 1.9 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 GAP92842.1 - 2.6e-100 329.1 16.4 3.5e-14 53.1 0.1 14.4 5 3 10 16 16 16 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP92842.1 - 7.5e-69 227.3 14.8 1.8e-11 44.3 0.0 16.5 12 4 4 17 17 17 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP92842.1 - 3e-62 199.2 15.4 0.00089 19.5 0.0 23.7 25 1 0 25 25 25 12 Ankyrin repeat Ank_5 PF13857.6 GAP92842.1 - 3e-59 196.3 14.6 5e-07 29.9 0.1 18.8 9 5 12 22 22 22 12 Ankyrin repeats (many copies) Ank PF00023.30 GAP92842.1 - 2.8e-51 169.8 37.0 6.9e-06 26.3 0.0 20.7 21 1 1 22 22 22 10 Ankyrin repeat VWA_3_C PF18571.1 GAP92842.1 - 0.0061 16.4 7.0 4.4 7.2 0.1 5.2 5 0 0 5 5 5 1 von Willebrand factor type A C-terminal domain DUF1843 PF08898.10 GAP92842.1 - 0.048 14.2 1.1 41 4.8 0.1 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) PC4 PF02229.16 GAP92843.1 - 2.4e-22 78.3 0.1 2.4e-22 78.3 0.1 1.9 3 0 0 3 3 3 1 Transcriptional Coactivator p15 (PC4) PXA PF02194.15 GAP92844.1 - 1.2e-33 116.6 0.2 2.3e-33 115.7 0.2 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 GAP92844.1 - 2.2e-21 76.5 0.0 6e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 GAP92844.1 - 0.00032 20.7 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 PX domain RIP PF00161.19 GAP92844.1 - 0.04 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribosome inactivating protein MAS20 PF02064.15 GAP92844.1 - 0.61 10.2 2.2 1.7 8.8 2.2 1.7 1 0 0 1 1 1 0 MAS20 protein import receptor Hydantoinase_B PF02538.14 GAP92845.1 - 8.4e-219 727.2 0.2 1.2e-218 726.7 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 GAP92845.1 - 4.9e-101 337.8 1.1 4.9e-101 337.8 1.1 1.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 GAP92845.1 - 1.7e-62 210.3 1.4 6.8e-61 205.1 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region tRNA-synt_2b PF00587.25 GAP92846.1 - 9.1e-36 123.5 0.0 1.4e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 GAP92846.1 - 2.6e-14 53.3 2.2 2.6e-14 53.3 2.2 1.9 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain NAGLU PF05089.12 GAP92847.1 - 1.2e-134 448.5 4.7 1.7e-134 448.0 4.7 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 GAP92847.1 - 3.5e-68 230.0 0.5 2.2e-67 227.4 0.2 2.1 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 GAP92847.1 - 4e-20 71.4 0.0 1.4e-19 69.6 0.0 2.0 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF5633 PF18656.1 GAP92847.1 - 0.0014 18.4 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5633) FAM196 PF15265.6 GAP92848.1 - 0.81 9.1 7.8 1.3 8.4 7.8 1.3 1 0 0 1 1 1 0 FAM196 family DUF4502 PF14950.6 GAP92848.1 - 3.9 6.8 12.0 6.3 6.1 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) PAF-AH_p_II PF03403.13 GAP92849.1 - 4.9e-10 38.5 0.0 5.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 GAP92849.1 - 0.0091 16.6 6.1 0.018 15.6 6.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP92849.1 - 0.01 15.1 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 GAP92849.1 - 0.016 14.9 0.1 0.033 13.8 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 GAP92849.1 - 0.053 13.0 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 GAP92849.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PI-PLC-X PF00388.19 GAP92851.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF3533 PF12051.8 GAP92851.1 - 3.5 6.4 7.4 4.9 6.0 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) SUR7 PF06687.12 GAP92852.1 - 1.6e-32 112.9 12.1 1.9e-32 112.7 12.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.9 GAP92852.1 - 3.8 6.2 6.0 62 2.2 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DWNN PF08783.11 GAP92853.1 - 9.3e-31 105.9 0.0 1.5e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 GAP92853.1 - 3.6e-09 36.3 6.3 6.8e-09 35.4 6.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 GAP92853.1 - 0.0007 19.6 0.9 0.0012 18.8 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 GAP92853.1 - 0.011 15.6 7.9 0.011 15.6 7.9 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 GAP92853.1 - 0.018 15.2 0.1 0.07 13.3 0.0 2.1 2 0 0 2 2 2 0 U-box domain zf-CCHC_3 PF13917.6 GAP92853.1 - 0.038 14.0 0.3 0.091 12.7 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-RING_6 PF14835.6 GAP92853.1 - 0.083 12.8 2.2 0.15 11.9 2.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE_2 PF02318.16 GAP92853.1 - 0.14 12.4 2.0 0.19 11.9 0.8 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_4 PF14570.6 GAP92853.1 - 0.14 12.0 5.8 0.29 10.9 5.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 GAP92853.1 - 0.31 11.4 6.2 0.72 10.2 6.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 GAP92853.1 - 2.8 8.2 8.4 9.4 6.5 8.4 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 GAP92853.1 - 5.7 6.9 8.8 11 6.0 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AMPK1_CBM PF16561.5 GAP92854.1 - 2.6e-05 24.4 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_20 PF00686.19 GAP92854.1 - 0.021 14.8 0.1 0.045 13.6 0.1 1.6 1 0 0 1 1 1 0 Starch binding domain DUF5421 PF17458.2 GAP92854.1 - 0.13 11.6 2.0 0.23 10.8 2.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) HD PF01966.22 GAP92855.1 - 9.9e-06 25.8 2.0 1.5e-05 25.2 1.1 1.8 2 1 0 2 2 2 1 HD domain F-box-like PF12937.7 GAP92856.1 - 0.0037 17.1 0.0 0.0099 15.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP92856.1 - 0.063 13.2 0.2 0.063 13.2 0.2 2.6 2 0 0 2 2 2 0 F-box domain CDC14 PF08045.11 GAP92858.1 - 1.2e-125 418.3 0.0 1.4e-125 418.2 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.17 GAP92860.1 - 9e-68 228.1 0.0 1.1e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Auts2 PF15336.6 GAP92860.1 - 0.052 13.7 3.0 0.08 13.1 3.0 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Collagen PF01391.18 GAP92860.1 - 0.096 12.5 1.3 0.18 11.6 1.3 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Coatomer_E PF04733.14 GAP92861.1 - 4e-64 216.8 5.6 4.5e-64 216.6 5.6 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 GAP92861.1 - 1.7e-08 34.8 22.8 0.0017 18.8 0.6 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAP92861.1 - 1.7e-07 30.8 4.7 0.0032 17.5 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP92861.1 - 4.7e-06 26.2 1.7 0.058 13.2 0.0 4.5 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP92861.1 - 1.8e-05 24.8 0.6 8.1 6.7 0.1 4.0 2 2 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 GAP92861.1 - 6.2e-05 23.4 6.5 0.1 13.2 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat Smr PF01713.21 GAP92861.1 - 0.00031 21.0 0.1 0.0017 18.7 0.0 2.1 2 0 0 2 2 2 1 Smr domain TPR_14 PF13428.6 GAP92861.1 - 0.00036 21.1 19.0 0.023 15.5 0.2 5.4 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAP92861.1 - 0.00041 20.6 9.2 0.01 16.1 0.1 4.7 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 GAP92861.1 - 0.0031 16.8 7.3 0.019 14.2 2.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 GAP92861.1 - 0.0057 16.8 2.7 1.3 9.4 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.6 GAP92861.1 - 0.017 14.5 3.6 1.4 8.2 0.1 2.9 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 GAP92861.1 - 0.03 14.0 0.5 0.03 14.0 0.5 3.4 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 GAP92861.1 - 0.036 14.2 9.3 0.12 12.5 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 GAP92861.1 - 0.041 14.0 3.2 2.3 8.3 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 SesA PF17107.5 GAP92861.1 - 0.056 13.6 0.3 8.2 6.6 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HrpB1_HrpK PF09613.10 GAP92861.1 - 0.087 12.5 2.7 0.31 10.7 0.5 2.5 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 GAP92861.1 - 0.17 12.5 0.2 0.17 12.5 0.2 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAP92861.1 - 0.18 12.3 1.1 16 6.1 0.1 4.3 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 GAP92861.1 - 0.84 10.5 25.2 0.76 10.6 2.1 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat Fungal_trans PF04082.18 GAP92863.1 - 3.8e-05 22.9 0.2 7.5e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_TACC PF12709.7 GAP92864.1 - 6.7e-10 39.3 1.3 6.7e-10 39.3 1.3 4.1 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins ATG16 PF08614.11 GAP92864.1 - 0.0032 17.7 4.6 0.0032 17.7 4.6 4.0 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Mucin PF01456.17 GAP92864.1 - 0.025 14.6 0.4 0.025 14.6 0.4 3.3 5 0 0 5 5 5 0 Mucin-like glycoprotein GIT_CC PF16559.5 GAP92864.1 - 0.031 14.1 2.7 4.4 7.2 0.0 3.8 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 GAP92864.1 - 1.4 8.2 24.5 2.1 7.6 5.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SKA1 PF07160.12 GAP92864.1 - 2.3 8.0 19.3 1 9.2 6.8 4.0 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 1 Rhomboid PF01694.22 GAP92865.1 - 5.7e-18 65.3 7.5 1e-17 64.6 7.5 1.3 1 0 0 1 1 1 1 Rhomboid family PTS_2-RNA PF01885.16 GAP92866.1 - 5.8e-19 68.8 0.0 8.1e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family zf-C4_Topoisom PF01396.19 GAP92867.1 - 0.053 13.3 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_SprT PF17283.2 GAP92868.1 - 0.85 9.6 4.6 2 8.4 4.6 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain NAP PF00956.18 GAP92869.1 - 3.5e-24 85.4 1.4 6.5e-24 84.5 1.3 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF5089 PF17002.5 GAP92869.1 - 0.0029 17.5 0.9 0.0057 16.6 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) Voldacs PF03517.13 GAP92869.1 - 0.026 14.7 4.9 0.039 14.1 4.9 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling DUF3246 PF11596.8 GAP92869.1 - 0.032 13.6 4.3 0.054 12.9 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 GAP92869.1 - 0.045 13.5 8.9 0.074 12.8 8.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein F-box-like PF12937.7 GAP92870.1 - 7.9e-08 32.1 0.0 1.9e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP92870.1 - 8.5e-05 22.3 0.0 0.00056 19.7 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 GAP92870.1 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 F-box Hexapep PF00132.24 GAP92871.1 - 6.7e-07 28.8 7.4 0.00098 18.8 1.8 4.3 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 GAP92871.1 - 0.00014 21.5 2.7 0.023 14.5 0.2 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 GAP92871.1 - 0.054 12.4 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Chromo PF00385.24 GAP92874.1 - 3.8e-08 33.1 0.1 8.2e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Rick_17kDa_Anti PF05433.15 GAP92875.1 - 0.00024 20.9 9.7 0.0023 17.8 0.2 2.4 2 0 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 GAP92875.1 - 0.0046 16.9 3.8 0.17 11.9 0.0 2.3 2 0 0 2 2 2 1 Glycine zipper Trp_oprn_chp PF09534.10 GAP92875.1 - 0.0089 15.8 0.3 0.016 15.0 0.3 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4235 PF14019.6 GAP92875.1 - 0.012 15.7 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) LapA_dom PF06305.11 GAP92875.1 - 0.38 10.6 0.7 2.5 8.0 0.2 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain zf-CCCH PF00642.24 GAP92877.1 - 0.0048 16.8 4.2 0.0048 16.8 4.2 2.9 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 GAP92877.1 - 0.0077 16.9 1.3 0.0077 16.9 1.3 2.3 1 1 1 2 2 2 1 Torus domain SNCAIP_SNCA_bd PF16700.5 GAP92877.1 - 0.065 13.0 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain Esterase_phd PF10503.9 GAP92878.1 - 4.5e-21 75.4 0.1 6e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 GAP92878.1 - 1.2e-06 28.1 0.2 2.8e-06 27.0 0.2 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 GAP92878.1 - 0.0044 16.7 1.7 0.013 15.2 1.7 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 GAP92878.1 - 0.016 15.0 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 GAP92878.1 - 0.042 13.7 0.1 0.062 13.1 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 GAP92878.1 - 0.092 12.4 3.7 0.12 12.0 3.7 1.5 1 1 0 1 1 1 0 Putative esterase AXE1 PF05448.12 GAP92878.1 - 0.2 10.3 0.1 0.51 9.0 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2920 PF11144.8 GAP92878.1 - 0.21 10.7 0.4 0.34 10.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Zn_clus PF00172.18 GAP92879.1 - 3.1e-07 30.4 10.9 4.9e-07 29.8 10.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC5_C PF14630.6 GAP92880.1 - 3.6e-81 272.8 0.0 4.9e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 GAP92880.1 - 1.5e-16 61.3 0.0 4.9e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 GAP92880.1 - 0.0015 18.8 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 GAP92880.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF3181 PF11378.8 GAP92880.1 - 0.18 12.1 0.0 0.45 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) AAA_7 PF12775.7 GAP92880.1 - 0.23 10.9 0.0 0.42 10.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Alpha-amylase_C PF02806.18 GAP92881.1 - 2e-26 92.3 0.0 5.6e-26 90.9 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 GAP92881.1 - 1.3e-18 67.1 0.0 4.4e-18 65.4 0.0 2.0 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 GAP92881.1 - 3.8e-16 59.6 0.3 5.9e-13 49.1 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 GAP92881.1 - 0.038 13.1 0.1 0.067 12.3 0.1 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Cellulase PF00150.18 GAP92881.1 - 0.055 12.9 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) AAA_2 PF07724.14 GAP92882.1 - 5.4e-35 121.0 0.0 2.4e-34 118.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 GAP92882.1 - 1.8e-13 51.1 0.2 3.6e-13 50.1 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAP92882.1 - 3e-08 33.7 0.0 7.9e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 GAP92882.1 - 2e-07 31.0 0.0 4.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 GAP92882.1 - 1.7e-05 24.1 0.0 3.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 GAP92882.1 - 0.00073 19.8 2.2 0.0016 18.7 0.2 2.4 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 GAP92882.1 - 0.0015 19.0 0.2 0.006 17.0 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_7 PF12775.7 GAP92882.1 - 0.0021 17.6 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 GAP92882.1 - 0.0035 17.4 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 GAP92882.1 - 0.0095 15.9 0.1 0.93 9.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 GAP92882.1 - 0.01 16.4 0.5 0.022 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAP92882.1 - 0.012 15.4 0.2 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 GAP92882.1 - 0.028 13.5 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 GAP92882.1 - 0.038 13.7 0.2 0.074 12.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAP92882.1 - 0.055 13.2 0.0 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 GAP92882.1 - 0.063 13.8 0.5 3.4 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAP92882.1 - 0.1 12.0 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 GAP92882.1 - 0.14 12.7 0.8 0.22 12.0 0.0 1.7 2 0 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 GAP92882.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 GAP92882.1 - 0.21 10.8 0.1 0.4 9.9 0.0 1.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.6 GAP92882.1 - 0.3 11.4 1.5 0.88 9.9 0.1 2.3 2 1 1 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 GAP92882.1 - 6.3 6.5 5.7 27 4.4 2.9 2.6 3 0 0 3 3 3 0 Cytidylate kinase COX4 PF02936.14 GAP92883.1 - 8.4e-47 158.7 0.0 9.8e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 GAP92883.1 - 0.016 15.7 0.1 0.028 14.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Mus7 PF09462.10 GAP92884.1 - 1.4e-122 410.6 1.7 2.3e-122 410.0 1.7 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family DUF3425 PF11905.8 GAP92885.1 - 3.2e-08 33.6 0.0 6.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Peptidase_S15 PF02129.18 GAP92886.1 - 5.3e-07 29.5 0.2 7.3e-07 29.1 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 GAP92886.1 - 0.00013 21.6 0.2 0.00064 19.3 0.2 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 GAP92886.1 - 0.059 12.0 0.1 0.11 11.2 0.1 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 GAP92886.1 - 0.092 12.2 0.1 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.28 GAP92887.1 - 2e-80 271.1 0.0 2.5e-74 251.0 0.1 2.2 1 1 1 2 2 2 2 Carboxylesterase family AAA PF00004.29 GAP92887.1 - 3.4e-40 137.5 0.0 3.4e-39 134.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Abhydrolase_3 PF07859.13 GAP92887.1 - 1.1e-12 48.3 0.1 2.7e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold AAA_lid_3 PF17862.1 GAP92887.1 - 2.3e-09 36.9 0.1 8.2e-09 35.1 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAP92887.1 - 1.7e-06 28.5 0.8 0.0021 18.4 0.0 3.6 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 GAP92887.1 - 1.1e-05 25.3 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 GAP92887.1 - 0.0013 18.8 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 GAP92887.1 - 0.0019 18.5 0.2 0.16 12.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 GAP92887.1 - 0.0048 16.7 0.0 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 GAP92887.1 - 0.02 15.1 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 GAP92887.1 - 0.033 13.4 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 GAP92887.1 - 0.035 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 GAP92887.1 - 0.035 14.6 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 GAP92887.1 - 0.048 14.0 1.0 0.13 12.7 0.0 2.2 3 0 0 3 3 1 0 RNA helicase AAA_5 PF07728.14 GAP92887.1 - 0.049 13.6 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 GAP92887.1 - 0.058 13.0 0.1 4.2 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 GAP92887.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ank_2 PF12796.7 GAP92889.1 - 1.8e-34 118.2 1.1 1.2e-07 32.2 0.0 8.7 5 1 6 11 11 11 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP92889.1 - 1.1e-24 83.8 0.3 0.081 13.5 0.0 11.5 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 GAP92889.1 - 1.5e-22 79.3 1.6 0.038 14.3 0.1 10.2 6 2 4 10 10 10 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAP92889.1 - 2e-21 76.1 5.0 0.0069 16.9 0.1 10.3 10 1 1 12 12 12 5 Ankyrin repeats (many copies) Clr5 PF14420.6 GAP92889.1 - 2.9e-19 69.0 3.0 7.6e-19 67.7 3.0 1.8 1 0 0 1 1 1 1 Clr5 domain Ank PF00023.30 GAP92889.1 - 4.6e-19 67.9 5.3 0.015 15.7 0.0 10.0 11 1 0 11 11 11 4 Ankyrin repeat zf-C2H2 PF00096.26 GAP92890.1 - 0.00076 19.8 20.1 0.36 11.4 0.4 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 GAP92890.1 - 0.0099 16.1 2.9 0.59 10.5 0.1 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 GAP92890.1 - 0.11 13.0 0.2 0.11 13.0 0.2 3.9 5 0 0 5 5 5 0 Zinc-finger double domain zf-met PF12874.7 GAP92890.1 - 0.21 12.0 3.9 1 9.8 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 GAP92890.1 - 1.7 9.0 6.8 0.98 9.8 0.2 2.6 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Chorismate_synt PF01264.21 GAP92891.1 - 8e-136 452.0 0.0 9.3e-136 451.8 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Acetyltransf_10 PF13673.7 GAP92892.1 - 3.2e-09 36.8 0.0 5.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 GAP92892.1 - 3.2e-08 33.8 0.0 5.5e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 GAP92892.1 - 3e-07 30.8 0.0 5.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 GAP92892.1 - 3.7e-05 23.8 0.0 8.9e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP92892.1 - 0.0006 19.7 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 GAP92892.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HD_5 PF13487.6 GAP92892.1 - 0.15 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 HD domain OPT PF03169.15 GAP92893.1 - 3.1e-99 333.3 24.3 5.4e-99 332.5 24.3 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Beta-lactamase PF00144.24 GAP92895.1 - 2.1e-43 148.8 0.0 3.3e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 GAP92895.1 - 6.2e-10 39.5 0.1 1.4e-09 38.3 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) Gal-bind_lectin PF00337.22 GAP92895.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Galactoside-binding lectin Beta-lactamase2 PF13354.6 GAP92895.1 - 0.19 11.3 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family TPR_12 PF13424.6 GAP92896.1 - 2.9e-12 46.7 6.0 8.1e-06 26.0 0.0 6.1 3 1 3 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.22 GAP92896.1 - 3.4e-08 33.0 0.0 7.3e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 GAP92896.1 - 1e-06 28.4 0.9 0.57 10.1 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 GAP92896.1 - 7.5e-06 26.4 0.1 7.8e-05 23.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain TPR_14 PF13428.6 GAP92896.1 - 3.1e-05 24.4 13.5 0.85 10.6 0.1 6.9 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 GAP92896.1 - 0.00029 20.3 1.1 0.00093 18.7 1.1 1.9 1 0 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 GAP92896.1 - 0.0018 18.2 13.3 1 9.6 0.1 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP92896.1 - 0.004 17.1 1.9 24 5.3 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 GAP92896.1 - 0.0051 16.9 9.8 10 6.6 0.4 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat Goodbye PF17109.5 GAP92896.1 - 0.0075 16.7 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain TPR_4 PF07721.14 GAP92896.1 - 0.013 16.1 5.2 0.26 12.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 GAP92896.1 - 0.022 15.4 4.3 8.5 7.1 0.0 3.8 3 1 0 3 3 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 GAP92896.1 - 0.036 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_1 PF00515.28 GAP92896.1 - 7.8 6.5 8.7 8.5 6.4 0.0 4.3 6 0 0 6 6 5 0 Tetratricopeptide repeat GMC_oxred_N PF00732.19 GAP92897.1 - 1.1e-59 202.3 0.0 1.6e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase UDPG_MGDP_dh_N PF03721.14 GAP92897.1 - 6.9e-37 126.8 0.1 2e-27 96.0 0.1 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 GAP92897.1 - 5.7e-32 109.8 0.0 1.3e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 GAP92897.1 - 1.4e-17 64.0 0.1 1.2e-16 61.0 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain GMC_oxred_C PF05199.13 GAP92897.1 - 2.5e-05 24.8 0.0 6.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 GAP92897.1 - 7.8e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 GAP92897.1 - 0.0004 19.7 0.0 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP92897.1 - 0.00084 19.5 0.1 0.0056 16.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 GAP92897.1 - 0.0012 19.1 0.2 0.065 13.5 0.0 3.3 3 0 0 3 3 3 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 GAP92897.1 - 0.015 15.3 0.1 16 5.5 0.0 3.3 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.24 GAP92897.1 - 0.03 13.4 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 GAP92897.1 - 0.032 12.9 0.2 0.081 11.6 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 GAP92897.1 - 0.061 12.6 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 GAP92897.1 - 0.096 12.2 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 GAP92897.1 - 0.11 12.4 0.0 0.48 10.4 0.0 2.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 GAP92897.1 - 0.14 11.4 0.3 0.46 9.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Melibiase_2 PF16499.5 GAP92898.1 - 6.5e-37 127.2 0.1 1.3e-36 126.3 0.1 1.5 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 GAP92898.1 - 9.9e-14 51.2 0.2 2.9e-13 49.7 0.2 1.9 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 GAP92898.1 - 0.0015 17.5 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 Melibiase ADH_zinc_N_2 PF13602.6 GAP92899.1 - 3.2e-15 57.3 0.0 5.4e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAP92899.1 - 9e-14 51.6 0.0 1.9e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP92899.1 - 0.00051 19.9 1.7 0.013 15.4 0.0 3.1 4 0 0 4 4 4 1 Alcohol dehydrogenase GroES-like domain DFP PF04127.15 GAP92899.1 - 0.057 13.2 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Pox_A14 PF05767.12 GAP92900.1 - 0.71 10.1 4.2 0.28 11.4 0.7 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Zn_clus PF00172.18 GAP92901.1 - 8.6e-07 29.0 12.8 1.6e-06 28.1 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 GAP92901.1 - 0.00023 20.1 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNase_T PF00929.24 GAP92902.1 - 5.5e-11 43.3 0.0 9.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 GAP92902.1 - 0.00047 20.2 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like Allantoicase PF03561.15 GAP92902.1 - 0.0085 16.1 0.3 0.0085 16.1 0.3 1.8 2 1 0 2 2 2 1 Allantoicase repeat Presenilin PF01080.17 GAP92902.1 - 6.3 5.4 11.4 0.82 8.4 0.2 2.1 2 0 0 2 2 2 0 Presenilin SR-25 PF10500.9 GAP92902.1 - 6.7 6.3 30.4 0.13 11.9 8.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HET PF06985.11 GAP92903.1 - 3.7e-24 85.7 0.0 1.7e-23 83.6 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Complex1_LYR_2 PF13233.6 GAP92904.1 - 2.7e-22 79.3 0.4 3.2e-22 79.1 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 GAP92904.1 - 0.043 13.9 0.8 0.073 13.1 0.8 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) NECFESHC PF16621.5 GAP92904.1 - 0.1 12.6 1.3 0.18 11.8 1.3 1.5 1 0 0 1 1 1 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 MMR_HSR1 PF01926.23 GAP92905.1 - 6.7e-17 61.6 0.0 1.2e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 GAP92905.1 - 1.4e-05 24.7 0.0 7.3e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 GAP92905.1 - 1.6e-05 24.9 0.0 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 GAP92905.1 - 0.0017 18.4 0.2 0.061 13.4 0.1 2.5 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 GAP92905.1 - 0.036 13.6 0.0 0.61 9.6 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B RNA_helicase PF00910.22 GAP92905.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DHHC PF01529.20 GAP92906.1 - 2.7e-31 108.4 1.0 6.2e-31 107.3 1.0 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Myb_DNA-bind_2 PF08914.11 GAP92907.1 - 1.9e-28 98.4 3.5 1.8e-20 72.9 0.2 2.7 2 0 0 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.8 GAP92907.1 - 2e-22 79.0 2.0 1.6e-21 76.1 0.0 2.8 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain ARID PF01388.21 GAP92907.1 - 4.2e-12 46.6 0.0 3e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Rap1-DNA-bind PF09197.10 GAP92907.1 - 2.5e-06 28.0 5.1 0.00016 22.2 0.9 3.3 1 1 2 3 3 3 2 Rap1, DNA-binding BRCT_2 PF16589.5 GAP92907.1 - 5.6e-06 26.7 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-binding PF00249.31 GAP92907.1 - 7.8e-05 22.8 3.5 0.17 12.1 1.2 3.5 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 GAP92907.1 - 0.006 16.8 9.8 0.094 13.0 0.7 3.7 4 0 0 4 4 4 2 Myb-like DNA-binding domain UBA PF00627.31 GAP92907.1 - 0.14 12.1 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain GFA PF04828.14 GAP92909.1 - 1.7e-19 69.9 0.0 2.3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF3431 PF11913.8 GAP92910.1 - 2e-05 24.5 0.0 6.1e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) E1-E2_ATPase PF00122.20 GAP92912.1 - 8.5e-48 162.3 2.1 3.8e-47 160.1 0.3 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 GAP92912.1 - 1.2e-37 130.3 0.1 3.7e-37 128.6 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 GAP92912.1 - 4.3e-20 71.9 2.0 8.9e-11 42.1 0.1 3.3 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 GAP92912.1 - 0.00015 21.6 1.3 0.00038 20.3 1.3 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 GAP92912.1 - 0.0011 19.5 0.0 0.0053 17.2 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Importin_rep_3 PF18806.1 GAP92912.1 - 0.018 15.1 0.0 0.052 13.6 0.0 1.7 1 0 0 1 1 1 0 Importin 13 repeat Glyco_hydro_61 PF03443.14 GAP92913.1 - 2e-51 174.9 0.0 2.4e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-C3HC PF07967.13 GAP92914.1 - 7.9e-41 139.2 0.2 1.7e-34 118.7 0.0 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 GAP92914.1 - 3.5e-26 91.2 0.2 3.5e-26 91.2 0.2 2.4 2 1 0 2 2 2 1 Rsm1-like BIR PF00653.21 GAP92914.1 - 0.0019 18.8 0.3 0.091 13.4 0.3 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain Inositol_P PF00459.25 GAP92915.1 - 2.2e-50 171.7 1.9 4e-50 170.8 1.9 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.23 GAP92916.1 - 4.7e-18 65.6 0.0 2.1e-10 41.1 0.0 3.0 2 1 1 3 3 3 2 Ribosomal protein L6 Tht1 PF04163.12 GAP92917.1 - 0.00089 18.1 2.1 0.0019 17.0 2.1 1.6 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF2884 PF11101.8 GAP92917.1 - 0.014 15.0 0.1 0.014 15.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2884) Chlorosome_CsmC PF11098.8 GAP92917.1 - 0.05 13.6 0.4 0.097 12.7 0.4 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C KIAA1430 PF13879.6 GAP92917.1 - 0.17 12.7 1.4 1.1 10.0 0.0 2.5 2 1 0 2 2 2 0 KIAA1430 homologue DUF3958 PF13125.6 GAP92917.1 - 0.35 11.1 4.5 1.9 8.7 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) Fib_alpha PF08702.10 GAP92917.1 - 1.5 9.0 6.2 1.1 9.4 3.8 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family AIP3 PF03915.13 GAP92917.1 - 1.6 7.8 9.7 3.6 6.6 9.7 1.5 1 1 1 2 2 2 0 Actin interacting protein 3 SR-25 PF10500.9 GAP92918.1 - 0.062 12.9 0.7 0.097 12.3 0.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AA_permease PF00324.21 GAP92919.1 - 3.8e-111 372.0 43.5 4.5e-111 371.8 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP92919.1 - 1.5e-26 93.2 48.5 2.4e-26 92.5 48.5 1.3 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 GAP92919.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Non-classical export protein 1 DIM PF08194.12 GAP92919.1 - 0.33 11.2 2.2 0.64 10.3 0.3 2.6 2 0 0 2 2 2 0 DIM protein Methyltransf_23 PF13489.6 GAP92920.1 - 4.3e-17 62.4 0.0 5.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP92920.1 - 2.2e-16 60.3 0.0 3.3e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP92920.1 - 4.8e-14 52.8 0.0 6.8e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP92920.1 - 1.2e-13 51.6 0.0 1.7e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP92920.1 - 1.1e-11 44.8 0.0 1.3e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAP92920.1 - 0.00017 21.1 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAP92920.1 - 0.0075 15.8 0.0 0.014 15.0 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 GAP92920.1 - 0.017 14.4 0.0 0.048 13.0 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DHBP_synthase PF00926.19 GAP92922.1 - 4.2e-82 274.3 0.0 5e-82 274.1 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF4439 PF14530.6 GAP92922.1 - 0.046 14.4 0.4 0.075 13.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) EcKinase PF02958.20 GAP92925.1 - 6.2e-10 38.9 0.0 2.1e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 GAP92925.1 - 1.5e-08 34.9 0.2 5e-07 29.9 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP92925.1 - 0.016 14.8 0.0 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Epimerase PF01370.21 GAP92926.1 - 1.6e-09 37.6 0.0 3.8e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 GAP92926.1 - 7.4e-09 35.8 0.3 1.2e-08 35.1 0.3 1.4 1 1 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 GAP92926.1 - 7.8e-09 35.3 0.0 1.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 HIM1 NAD_binding_4 PF07993.12 GAP92926.1 - 0.00023 20.4 0.1 0.018 14.2 0.0 2.7 2 1 1 3 3 3 1 Male sterility protein NmrA PF05368.13 GAP92926.1 - 0.0012 18.4 0.1 0.0022 17.6 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 GAP92926.1 - 0.0089 16.5 0.0 0.03 14.7 0.0 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 GAP92926.1 - 0.026 13.5 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1471 PF07338.13 GAP92926.1 - 0.08 12.9 0.2 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) Putative_PNPOx PF01243.20 GAP92927.1 - 6e-05 23.2 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3704 PF12488.8 GAP92927.1 - 0.29 10.8 2.7 5.7 6.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) Pectinesterase PF01095.19 GAP92929.1 - 4.1e-14 52.0 0.0 1.2e-13 50.4 0.0 1.7 2 1 0 2 2 2 1 Pectinesterase Big_5 PF13205.6 GAP92929.1 - 1.1e-06 29.3 2.3 0.00014 22.5 1.0 3.2 2 1 0 2 2 2 1 Bacterial Ig-like domain eIF_4G1 PF12152.8 GAP92930.1 - 0.31 11.2 4.9 9.5 6.5 0.4 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 4G1 Phage_ABA_S PF18066.1 GAP92930.1 - 0.34 11.6 2.4 22 5.8 2.4 3.1 1 1 0 1 1 1 0 Phage ABA sandwich domain CH PF00307.31 GAP92930.1 - 0.95 9.7 9.5 9.7e+02 -0.0 9.5 3.7 1 1 0 1 1 1 0 Calponin homology (CH) domain DUF3328 PF11807.8 GAP92931.1 - 6.1e-44 150.4 0.2 8.1e-44 150.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2116 PF09889.9 GAP92932.1 - 0.039 13.9 0.1 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3377 PF11857.8 GAP92932.1 - 0.054 13.4 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3328 PF11807.8 GAP92932.1 - 4.5 7.0 9.0 1.1e+02 2.5 9.0 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) VPS38 PF17649.1 GAP92933.1 - 0.063 12.1 0.1 0.087 11.7 0.1 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Phage_holin_2_2 PF10746.9 GAP92933.1 - 0.14 11.8 0.2 0.14 11.8 0.2 2.2 3 0 0 3 3 3 0 Phage holin T7 family, holin superfamily II Gemini_mov PF01708.16 GAP92933.1 - 0.55 10.0 6.6 0.23 11.2 2.9 2.2 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF2070 PF09843.9 GAP92933.1 - 1.1 7.5 7.4 1.9 6.7 7.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ank_2 PF12796.7 GAP92934.1 - 2.7e-37 127.2 1.6 1.1e-10 41.9 0.0 5.7 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP92934.1 - 9.7e-37 124.9 3.0 2.2e-08 34.5 0.1 8.1 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP92934.1 - 4.7e-28 94.1 2.0 0.0018 18.6 0.0 9.4 8 1 1 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 GAP92934.1 - 1.2e-27 95.6 14.2 1.3e-06 28.6 0.1 7.6 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 GAP92934.1 - 5.7e-24 83.5 8.7 0.00018 21.8 0.3 8.4 7 1 0 7 7 7 5 Ankyrin repeat AAA_16 PF13191.6 GAP92934.1 - 3.6e-06 27.5 0.1 4.5e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 GAP92934.1 - 5.4e-05 23.2 0.0 0.00022 21.2 0.0 2.0 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 GAP92934.1 - 0.0041 16.4 0.1 0.0093 15.2 0.1 1.5 1 1 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 GAP92934.1 - 0.0062 15.8 0.1 0.59 9.3 0.1 2.3 2 0 0 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.6 GAP92934.1 - 0.17 12.1 0.0 0.67 10.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 GAP92934.1 - 0.21 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 GAP92935.1 - 8.7e-17 61.5 0.1 3.2e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain HEAT_2 PF13646.6 GAP92935.1 - 5.9e-07 29.8 8.0 0.16 12.4 0.2 6.1 5 2 1 7 7 7 2 HEAT repeats AAA_18 PF13238.6 GAP92935.1 - 1.9e-05 25.2 0.1 0.00029 21.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 GAP92935.1 - 2.9e-05 24.4 0.0 0.03 14.6 0.0 4.5 5 0 0 5 5 4 1 AAA domain AAA PF00004.29 GAP92935.1 - 0.0001 22.7 0.0 0.00048 20.6 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PGAP1 PF07819.13 GAP92935.1 - 0.00012 21.9 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.6 GAP92935.1 - 0.0016 18.8 0.3 0.016 15.6 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 GAP92935.1 - 0.002 18.5 0.9 0.047 14.1 0.1 3.2 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 GAP92935.1 - 0.0047 16.7 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF676 PF05057.14 GAP92935.1 - 0.0054 16.3 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) NB-ARC PF00931.22 GAP92935.1 - 0.0064 15.7 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Abhydrolase_6 PF12697.7 GAP92935.1 - 0.014 16.0 0.4 0.073 13.7 0.0 2.5 3 0 0 3 3 2 0 Alpha/beta hydrolase family DUF2267 PF10025.9 GAP92935.1 - 0.018 15.3 2.1 0.068 13.5 0.1 2.9 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2267) NLRC4_HD2 PF17776.1 GAP92935.1 - 0.033 14.7 0.1 0.033 14.7 0.1 3.2 3 1 1 4 4 4 0 NLRC4 helical domain HD2 Hydrolase_4 PF12146.8 GAP92935.1 - 0.039 13.2 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SRP54 PF00448.22 GAP92935.1 - 0.042 13.5 0.1 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 GAP92935.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 GAP92935.1 - 0.062 13.7 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_14 PF13173.6 GAP92935.1 - 0.073 13.1 0.1 0.22 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAP92935.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 GAP92935.1 - 0.19 11.8 0.0 1.9 8.6 0.0 2.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF3433 PF11915.8 GAP92936.1 - 1e-23 83.6 12.3 1.2e-19 70.5 3.1 3.7 3 1 0 3 3 3 2 Protein of unknown function (DUF3433) BNR_2 PF13088.6 GAP92938.1 - 3.9e-07 29.7 0.0 0.00033 20.0 0.0 2.2 2 0 0 2 2 2 2 BNR repeat-like domain fn3 PF00041.21 GAP92939.1 - 0.005 17.2 3.7 0.0065 16.8 2.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain Pyridoxal_deC PF00282.19 GAP92940.1 - 2.7e-64 217.2 0.0 4e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 GAP92940.1 - 0.00044 19.3 0.0 0.001 18.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V FSA_C PF10479.9 GAP92941.1 - 0.47 8.5 9.4 0.54 8.3 9.4 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 GAP92941.1 - 2.7 6.1 19.3 3.2 5.9 19.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pex14_N PF04695.13 GAP92943.1 - 0.025 15.2 0.4 0.039 14.6 0.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.32 GAP92944.1 - 1.3e-09 38.5 14.8 0.00065 20.5 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 GAP92944.1 - 2e-05 24.1 8.4 3.9e-05 23.2 8.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 GAP92944.1 - 0.0031 17.8 0.0 0.007 16.6 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 GAP92944.1 - 0.092 13.1 6.8 0.2 12.0 6.8 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_9 PF13901.6 GAP92944.1 - 1.2 9.0 7.1 2.2 8.2 7.1 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon UQ_con PF00179.26 GAP92945.1 - 1.5e-46 157.5 0.0 1.7e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 GAP92945.1 - 0.00025 20.8 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 GAP92945.1 - 0.083 12.8 0.1 0.15 11.9 0.1 1.5 1 1 0 1 1 1 0 UEV domain ADH_zinc_N PF00107.26 GAP92946.1 - 6.6e-15 55.2 0.9 1.3e-14 54.2 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP92946.1 - 4.3e-06 27.8 0.1 7.7e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4265 PF14085.6 GAP92946.1 - 0.0051 16.8 0.0 0.76 9.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4265) SET PF00856.28 GAP92947.1 - 1.1e-13 51.9 0.0 1.5e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 SET domain CBP4 PF07960.11 GAP92948.1 - 9.2e-32 109.6 0.7 1.2e-31 109.2 0.7 1.1 1 0 0 1 1 1 1 CBP4 HSF_DNA-bind PF00447.17 GAP92948.1 - 0.061 13.9 0.0 0.074 13.7 0.0 1.1 1 0 0 1 1 1 0 HSF-type DNA-binding Endonuc_Holl PF10107.9 GAP92948.1 - 0.078 12.8 3.7 0.1 12.4 3.7 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF2165 PF09933.9 GAP92948.1 - 0.22 11.5 0.2 0.3 11.1 0.2 1.2 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Sel1 PF08238.12 GAP92949.1 - 3.3e-48 161.0 20.5 1.4e-07 31.9 0.1 7.8 7 0 0 7 7 7 7 Sel1 repeat Pkinase PF00069.25 GAP92950.1 - 1e-06 28.3 0.0 6.8e-05 22.4 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP92950.1 - 1.3e-06 28.0 0.0 0.0002 20.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase UB2H PF14814.6 GAP92950.1 - 0.078 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain TrmO_C PF18389.1 GAP92950.1 - 0.13 12.4 0.2 14 5.9 0.0 2.6 2 0 0 2 2 2 0 TrmO C-terminal domain Helo_like_N PF17111.5 GAP92951.1 - 0.037 13.4 1.2 0.14 11.5 0.1 2.3 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Apolipoprotein PF01442.18 GAP92951.1 - 0.042 13.7 1.7 0.1 12.4 1.7 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ING PF12998.7 GAP92951.1 - 0.22 12.1 0.7 6.8 7.4 0.4 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding FliJ PF02050.16 GAP92951.1 - 0.69 10.1 3.2 3.8 7.7 0.4 2.8 2 0 0 2 2 2 0 Flagellar FliJ protein WD40 PF00400.32 GAP92952.1 - 8e-57 187.9 34.9 8.2e-10 39.1 0.3 11.8 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP92952.1 - 5.1e-24 84.4 1.1 0.01 16.1 0.0 10.1 5 3 6 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 GAP92952.1 - 7e-16 58.1 0.1 0.05 12.6 0.0 8.1 4 3 4 8 8 8 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 GAP92952.1 - 0.00034 20.5 10.2 2.2 8.3 0.0 7.3 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 GAP92952.1 - 0.0017 17.2 0.1 8.8 4.9 0.1 4.2 3 1 2 5 5 5 2 Nup133 N terminal like Proteasome_A_N PF10584.9 GAP92952.1 - 0.0047 16.6 3.6 5.1 6.9 0.0 4.8 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Nbas_N PF15492.6 GAP92952.1 - 0.0062 15.9 12.7 10 5.3 0.1 6.9 6 4 3 9 9 9 2 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 GAP92952.1 - 0.0083 15.1 2.1 10 4.9 0.0 4.3 4 1 1 5 5 5 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 GAP92952.1 - 0.0086 14.8 3.5 1.4 7.5 0.1 3.9 2 1 0 3 3 3 1 Nucleoporin Nup120/160 MMS1_N PF10433.9 GAP92952.1 - 0.045 12.4 0.0 0.23 10.1 0.0 2.1 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term HTH_32 PF13565.6 GAP92953.1 - 4.1e-06 27.3 4.6 5.3e-06 27.0 0.7 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 GAP92953.1 - 5.1e-05 22.9 0.5 0.009 15.8 0.0 3.0 3 1 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 GAP92953.1 - 0.0012 18.6 0.5 0.044 13.6 0.0 2.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 GAP92953.1 - 0.0013 18.8 0.1 0.016 15.3 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase DUF2285 PF10074.9 GAP92953.1 - 0.0018 18.9 1.5 0.33 11.6 0.2 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2285) HTH_Tnp_Tc3_2 PF01498.18 GAP92953.1 - 0.0019 18.4 0.7 0.0041 17.3 0.3 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 GAP92953.1 - 0.009 16.0 0.5 0.075 13.1 0.0 2.7 3 1 0 3 3 3 1 Winged helix-turn helix MarR_2 PF12802.7 GAP92953.1 - 0.029 14.2 0.1 0.56 10.1 0.0 2.3 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 GAP92953.1 - 0.078 12.6 0.4 0.45 10.1 0.0 2.3 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 GAP92953.1 - 0.086 13.0 1.3 0.55 10.4 0.1 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain Strabismus PF06638.11 GAP92953.1 - 0.2 10.2 1.0 0.27 9.9 1.0 1.1 1 0 0 1 1 1 0 Strabismus protein HET PF06985.11 GAP92954.1 - 2.3e-28 99.4 0.2 1.7e-27 96.6 0.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ArabFuran-catal PF09206.11 GAP92955.1 - 3.8e-147 489.7 9.0 5.3e-147 489.2 9.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 GAP92955.1 - 1.3e-48 164.6 0.3 2.1e-48 163.9 0.3 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain zf-3CxxC PF13695.6 GAP92956.1 - 4.2e-22 78.5 0.7 6.9e-22 77.8 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 GAP92956.1 - 0.22 12.3 6.8 1.9 9.3 2.0 2.9 2 1 0 2 2 2 0 Zinc-binding domain BNR_2 PF13088.6 GAP92957.1 - 7.8e-16 58.2 0.3 4.7e-10 39.2 0.4 2.7 1 1 1 2 2 2 2 BNR repeat-like domain BNR_3 PF13859.6 GAP92957.1 - 0.00041 19.7 0.0 0.0029 16.9 0.0 2.0 1 1 0 2 2 2 1 BNR repeat-like domain BNR PF02012.20 GAP92957.1 - 0.00071 19.2 33.0 1.3 9.3 0.2 6.9 8 0 0 8 8 8 5 BNR/Asp-box repeat PPDFL PF15060.6 GAP92957.1 - 0.0025 18.3 0.4 0.0059 17.1 0.4 1.5 1 0 0 1 1 1 1 Differentiation and proliferation regulator Mo-co_dimer PF03404.16 GAP92957.1 - 0.0094 16.0 3.9 0.028 14.4 0.1 3.0 4 0 0 4 4 4 1 Mo-co oxidoreductase dimerisation domain CDC48_2 PF02933.17 GAP92957.1 - 0.068 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 AA_permease_2 PF13520.6 GAP92958.1 - 1.3e-62 212.0 34.3 1.9e-62 211.5 34.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 GAP92958.1 - 1.7e-26 92.9 22.9 1.7e-26 92.9 22.9 2.0 2 0 0 2 2 2 1 Amino acid permease ADH_zinc_N PF00107.26 GAP92959.1 - 5.3e-28 97.6 0.0 9.3e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP92959.1 - 1.6e-24 85.9 0.1 2.9e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAP92959.1 - 2.6e-05 25.3 0.0 6.5e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 GAP92959.1 - 0.0001 21.8 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 GAP92959.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated tRNA-synt_1 PF00133.22 GAP92960.1 - 1.2e-47 162.5 0.0 3.3e-29 101.6 0.0 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 GAP92960.1 - 2.4e-33 115.2 0.0 4.7e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 GAP92960.1 - 5e-29 101.2 0.0 1.3e-21 76.9 0.0 4.6 4 1 1 5 5 5 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 GAP92960.1 - 4.9e-10 39.6 0.0 1.2e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA Zn-ribbon_8 PF09723.10 GAP92960.1 - 0.32 11.1 1.9 0.81 9.9 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain HAT_KAT11 PF08214.11 GAP92962.1 - 3.6e-88 296.2 0.0 4.7e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein DUF5558 PF17713.1 GAP92962.1 - 0.58 10.6 7.3 0.63 10.4 4.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5558) Ribonucleas_3_3 PF14622.6 GAP92963.1 - 1.5e-25 89.9 0.0 3e-25 88.9 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 GAP92963.1 - 0.067 13.8 0.0 0.15 12.7 0.0 1.7 1 1 0 1 1 1 0 Ribonuclease III domain Peptidase_S8 PF00082.22 GAP92965.1 - 1.3e-16 60.7 0.1 2.4e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Subtilase family DUF1627 PF07789.12 GAP92965.1 - 0.13 11.9 0.1 0.93 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1627) HET PF06985.11 GAP92967.1 - 9.8e-30 103.8 2.9 9.8e-30 103.8 2.9 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SUA5 PF03481.13 GAP92967.1 - 0.085 13.4 1.0 2.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Putative GTP-binding controlling metal-binding dUTPase PF00692.19 GAP92968.1 - 2.1e-09 37.1 0.0 2.5e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 dUTPase MFS_1 PF07690.16 GAP92970.1 - 2e-30 105.9 32.2 2e-30 105.9 32.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S9 PF00326.21 GAP92971.1 - 1.2e-45 155.6 1.1 1.9e-45 155.0 1.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 GAP92971.1 - 4.4e-06 26.5 0.1 0.0081 16.1 0.0 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat MFS_1 PF07690.16 GAP92972.1 - 5.5e-43 147.2 25.3 5.5e-43 147.2 25.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP92972.1 - 5.9e-15 55.1 4.9 5.9e-15 55.1 4.9 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 GAP92972.1 - 0.00044 18.7 1.0 0.00044 18.7 1.0 2.6 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 GAP92972.1 - 0.22 10.4 9.7 0.65 8.8 0.2 2.4 2 1 0 2 2 2 0 MFS_1 like family RseC_MucC PF04246.12 GAP92972.1 - 2.8 7.9 6.0 4.2 7.3 1.1 2.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Patatin PF01734.22 GAP92973.1 - 2.3e-14 54.1 0.0 5.6e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.27 GAP92973.1 - 0.0015 19.1 0.0 0.0037 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 GAP92973.1 - 0.0096 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 GAP92973.1 - 0.017 15.2 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 GAP92973.1 - 0.025 14.9 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Tiam_CC_Ex PF18385.1 GAP92973.1 - 0.16 12.4 0.0 0.47 10.9 0.0 1.7 2 0 0 2 2 1 0 T-lymphoma invasion and metastasis CC-Ex domain zf-C3HC4_3 PF13920.6 GAP92973.1 - 0.18 11.7 8.9 0.39 10.6 8.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 GAP92973.1 - 0.37 10.8 11.2 0.97 9.5 11.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 GAP92973.1 - 0.54 10.6 10.0 1.3 9.4 10.0 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 GAP92973.1 - 1.7 8.6 8.0 3.8 7.5 8.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 GAP92973.1 - 3.6 7.5 9.4 8.5 6.3 9.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pyr_redox_3 PF13738.6 GAP92974.1 - 6e-10 38.9 0.0 1.7e-08 34.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 GAP92974.1 - 1.5e-09 36.9 0.0 2.2e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 GAP92974.1 - 6.8e-08 32.0 0.0 2.8e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 GAP92974.1 - 1.2e-07 31.3 0.0 3.5e-07 29.8 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP92974.1 - 6.9e-06 26.2 0.1 2.7e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP92974.1 - 0.00062 19.5 0.6 1 8.9 0.0 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 GAP92974.1 - 0.0034 16.7 0.0 0.01 15.1 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 GAP92974.1 - 0.042 14.4 0.2 13 6.5 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 GAP92976.1 - 3.4e-35 121.6 23.6 3.4e-35 121.6 23.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP92976.1 - 5e-11 42.1 3.1 5e-11 42.1 3.1 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.21 GAP92976.1 - 0.0099 14.7 3.1 0.035 12.9 0.1 2.3 2 0 0 2 2 2 1 POT family adh_short PF00106.25 GAP92977.1 - 3.5e-16 59.2 0.0 5.2e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 GAP92977.1 - 6.5e-07 29.4 0.1 1.5e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 GAP92977.1 - 2.6e-05 23.9 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GMC_oxred_N PF00732.19 GAP92978.1 - 7.4e-50 170.0 0.0 9.9e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP92978.1 - 1.4e-36 126.2 0.0 2.2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 GAP92978.1 - 1.7e-05 24.6 0.0 6.5e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 GAP92978.1 - 0.00017 20.7 0.1 0.00029 20.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAP92978.1 - 0.00052 19.2 0.5 0.0039 16.3 0.9 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP92978.1 - 0.00059 19.1 0.5 0.0016 17.7 0.4 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP92978.1 - 0.0023 17.2 0.4 0.93 8.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP92978.1 - 0.0031 17.7 2.6 0.013 15.7 1.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAP92978.1 - 0.094 11.9 0.7 0.16 11.2 0.7 1.3 1 0 0 1 1 1 0 Thi4 family HHH_5 PF14520.6 GAP92978.1 - 0.14 12.7 0.1 5.5 7.7 0.1 2.5 1 1 0 1 1 1 0 Helix-hairpin-helix domain Pyr_redox PF00070.27 GAP92978.1 - 0.21 12.2 2.2 3.1 8.4 0.5 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.22 GAP92979.1 - 7.3e-17 62.3 0.1 1.4e-16 61.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAP92979.1 - 1.1e-08 35.0 0.0 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 GAP92979.1 - 0.006 17.2 0.0 0.01 16.5 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 GAP92979.1 - 0.013 16.5 0.0 0.055 14.5 0.0 2.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase NAD_kinase PF01513.21 GAP92980.1 - 4.3e-48 164.0 0.0 5.5e-47 160.4 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 GAP92980.1 - 0.15 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MT0933_antitox PF14013.6 GAP92981.1 - 0.077 13.3 4.5 0.19 12.0 4.5 1.8 1 1 0 1 1 1 0 MT0933-like antitoxin protein Serglycin PF04360.12 GAP92982.1 - 0.031 14.2 0.5 0.049 13.6 0.5 1.3 1 0 0 1 1 1 0 Serglycin MRJP PF03022.16 GAP92983.1 - 5.2e-35 121.2 0.0 7.4e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 GAP92983.1 - 0.00063 19.4 0.0 0.011 15.3 0.0 2.7 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 GAP92983.1 - 0.0018 18.2 0.9 9.6 6.5 0.0 4.1 3 0 0 3 3 3 2 NHL repeat PD40 PF07676.12 GAP92983.1 - 0.0036 17.2 0.1 0.94 9.5 0.1 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Abhydrolase_2 PF02230.16 GAP92984.1 - 1.9e-23 83.4 0.0 8.6e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 GAP92984.1 - 2e-05 24.0 0.3 0.57 9.4 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAP92984.1 - 2.6e-05 23.8 0.1 0.00011 21.7 0.0 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 GAP92984.1 - 7.4e-05 23.5 10.8 0.0049 17.5 6.4 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 GAP92984.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 GAP92984.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 GAP92984.1 - 0.018 14.7 0.8 0.28 10.8 0.4 3.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 GAP92984.1 - 0.021 14.7 0.1 5.8 6.7 0.0 2.7 3 0 0 3 3 3 0 alpha/beta hydrolase fold Peptidase_M24 PF00557.24 GAP92985.1 - 4.5e-46 157.2 0.0 6.1e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 GAP92985.1 - 2.7e-18 66.0 11.7 2.7e-18 66.0 11.7 1.6 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 GAP92985.1 - 0.0024 17.9 8.9 0.0024 17.9 8.9 2.0 2 0 0 2 2 2 1 MYND finger DUF1729 PF08354.10 GAP92987.1 - 1e-139 465.4 0.0 1.6e-139 464.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 GAP92987.1 - 7.1e-61 206.5 0.1 4.4e-59 200.6 0.0 2.7 3 1 0 3 3 3 1 Acyl transferase domain SAT PF16073.5 GAP92987.1 - 5e-26 91.9 0.0 1.2e-25 90.6 0.0 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 GAP92987.1 - 3.4e-25 88.0 0.0 7.1e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_meander PF17951.1 GAP92987.1 - 7.9e-08 32.2 0.0 2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MmgE_PrpD PF03972.14 GAP92988.1 - 8.6e-115 383.8 0.0 1.1e-114 383.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family MmgE_PrpD PF03972.14 GAP92989.1 - 1.7e-110 369.6 0.0 2.1e-110 369.3 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family TSCPD PF12637.7 GAP92989.1 - 0.17 12.1 0.2 3.4 8.0 0.0 2.9 3 0 0 3 3 3 0 TSCPD domain Fungal_trans PF04082.18 GAP92990.1 - 5.9e-10 38.6 2.3 5.8e-09 35.4 2.3 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP92990.1 - 9.4e-10 38.5 12.8 2e-09 37.4 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fas_alpha_ACP PF18325.1 GAP92991.1 - 1.4e-56 191.3 0.0 3e-56 190.2 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 GAP92991.1 - 4e-37 127.8 0.3 6.8e-37 127.1 0.3 1.3 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 GAP92991.1 - 6.2e-23 81.7 0.2 1.4e-22 80.5 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 GAP92991.1 - 1.4e-17 63.8 0.0 2.9e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 GAP92991.1 - 1.6e-08 34.3 0.0 3.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP92991.1 - 1.6e-05 24.6 0.0 3.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP92991.1 - 0.036 14.0 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 KR domain Citrate_synt PF00285.21 GAP92992.1 - 1.6e-105 353.2 0.0 1.9e-105 352.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain HET PF06985.11 GAP92993.1 - 1.2e-05 25.7 0.0 0.00099 19.5 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DnaJ PF00226.31 GAP92994.1 - 8.8e-17 61.0 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain LprI PF07007.12 GAP92994.1 - 0.00068 20.3 0.1 0.00068 20.3 0.1 1.6 2 0 0 2 2 2 1 Lysozyme inhibitor LprI Tannase PF07519.11 GAP92995.1 - 1.6e-100 337.2 0.0 2.5e-100 336.6 0.0 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 GAP92995.1 - 0.003 16.9 0.0 0.46 9.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 GAP92995.1 - 0.041 13.4 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family GHD PF17834.1 GAP92995.1 - 0.14 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase Glyco_hydro_43 PF04616.14 GAP92996.1 - 1.3e-46 159.2 2.6 1.5e-46 159.0 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cas_Cas2CT1978 PF09707.10 GAP92996.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Methyltransf_25 PF13649.6 GAP92997.1 - 4.8e-10 40.0 0.1 6.7e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP92997.1 - 4.3e-08 33.1 0.0 5.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP92997.1 - 8.9e-07 29.5 0.0 1.2e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP92997.1 - 1.2e-06 28.2 0.1 1.5e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 GAP92997.1 - 6.9e-06 26.0 0.0 8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP92997.1 - 2e-05 25.3 0.0 3.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAP92997.1 - 0.00038 20.5 0.0 0.00047 20.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAP92997.1 - 0.00057 19.4 0.1 0.00065 19.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 GAP92997.1 - 0.00059 19.2 0.0 0.00067 19.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 GAP92997.1 - 0.0011 18.8 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 GAP92997.1 - 0.0028 17.6 0.0 0.0036 17.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 GAP92997.1 - 0.0073 15.6 0.0 0.0093 15.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 GAP92997.1 - 0.0096 15.3 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB DREV PF05219.12 GAP92997.1 - 0.029 13.5 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase TPR_2 PF07719.17 GAP92998.1 - 3.7e-10 39.1 1.9 0.0012 18.8 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP92998.1 - 2.1e-09 36.8 1.2 0.051 13.4 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 GAP92998.1 - 6.5e-09 36.0 15.1 0.0045 17.2 0.3 4.4 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAP92998.1 - 1.3e-05 25.0 2.4 2.6 8.5 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat HET PF06985.11 GAP92998.1 - 6.2e-05 23.4 1.3 0.00028 21.2 1.3 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_14 PF13428.6 GAP92998.1 - 0.00046 20.8 7.5 15 6.7 0.1 6.4 2 2 3 5 5 5 0 Tetratricopeptide repeat Ank_4 PF13637.6 GAP92998.1 - 0.0031 18.0 0.0 0.0099 16.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TPR_6 PF13174.6 GAP92998.1 - 0.014 16.0 0.3 8.8 7.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_5 PF13857.6 GAP92998.1 - 0.021 15.1 0.1 0.16 12.3 0.0 2.5 2 1 1 3 3 2 0 Ankyrin repeats (many copies) Telomere_res PF16684.5 GAP92998.1 - 0.025 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Telomere resolvase TPR_10 PF13374.6 GAP92998.1 - 0.045 13.6 6.6 5 7.1 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Oscp1 PF10188.9 GAP92998.1 - 0.14 12.2 0.1 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Organic solute transport protein 1 Rootletin PF15035.6 GAP92998.1 - 0.74 9.8 5.1 0.64 10.0 2.8 1.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion TPR_7 PF13176.6 GAP92998.1 - 2.2 8.5 12.0 21 5.5 0.2 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Acyl-CoA_dh_1 PF00441.24 GAP92999.1 - 7.1e-18 65.3 4.3 1.2e-17 64.5 4.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 GAP92999.1 - 1.2e-08 35.0 0.0 2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 GAP92999.1 - 0.00024 21.4 6.1 0.00024 21.4 6.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 GAP92999.1 - 0.0014 19.3 0.0 0.0031 18.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain AMP-binding PF00501.28 GAP93000.1 - 4e-88 295.8 0.0 7.6e-88 294.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 GAP93000.1 - 8.7e-87 290.9 0.1 2.2e-86 289.5 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAP93000.1 - 4.9e-57 193.9 0.1 7.4e-57 193.3 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 GAP93000.1 - 2.9e-55 187.0 0.1 1.8e-53 181.1 0.1 2.7 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 GAP93000.1 - 6.1e-46 156.7 0.0 7.1e-45 153.2 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 GAP93000.1 - 5.4e-42 142.5 0.7 1.1e-41 141.5 0.7 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 GAP93000.1 - 3e-19 69.1 0.0 1.5e-09 38.0 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 GAP93000.1 - 1.7e-13 51.0 0.0 9.5e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 GAP93000.1 - 1.7e-11 44.0 0.0 3.4e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 GAP93000.1 - 1.7e-08 35.3 0.0 4.8e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 GAP93000.1 - 1.1e-06 28.3 0.2 5.4e-05 22.7 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 GAP93000.1 - 1.7e-06 27.7 0.0 0.00069 19.1 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAP93000.1 - 2e-06 27.2 0.0 0.016 14.4 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 GAP93000.1 - 2.1e-05 24.0 0.2 4.3e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 GAP93000.1 - 0.0029 16.7 0.0 0.44 9.5 0.0 2.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 GAP93000.1 - 0.1 12.2 1.6 0.74 9.3 0.0 2.7 3 0 0 3 3 2 0 NmrA-like family PglL_A PF15864.5 GAP93000.1 - 0.18 11.6 1.1 0.44 10.3 1.1 1.7 1 0 0 1 1 1 0 Protein glycosylation ligase RmlD_sub_bind PF04321.17 GAP93000.1 - 0.18 10.9 0.4 16 4.5 0.0 2.9 3 0 0 3 3 3 0 RmlD substrate binding domain PhyH PF05721.13 GAP93001.1 - 4.8e-16 59.7 0.0 7.5e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NAD_binding_10 PF13460.6 GAP93002.1 - 1.6e-05 24.9 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 GAP93002.1 - 4.4e-05 23.1 0.0 7.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 GAP93002.1 - 0.0052 16.3 0.0 0.052 13.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 GAP93002.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain P5CR_dimer PF14748.6 GAP93003.1 - 1.2e-27 96.1 1.0 2.2e-27 95.3 1.0 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 GAP93003.1 - 8.1e-12 45.6 0.1 3.9e-11 43.4 0.0 2.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 GAP93003.1 - 0.00066 18.8 0.8 0.19 10.7 0.0 2.2 1 1 1 2 2 2 2 Prephenate dehydrogenase TMEM215 PF15746.5 GAP93003.1 - 0.021 14.3 0.2 0.051 13.0 0.2 1.7 1 1 0 1 1 1 0 TMEM215 family CorA PF01544.18 GAP93005.1 - 0.0023 17.3 0.5 0.0036 16.7 0.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein P120R PF08062.11 GAP93006.1 - 0.68 10.4 3.2 1.2 9.5 3.2 1.4 1 0 0 1 1 1 0 P120R (NUC006) repeat HET PF06985.11 GAP93007.1 - 5e-23 82.1 1.7 1.4e-22 80.6 0.0 2.5 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Cytomega_UL84 PF06284.11 GAP93007.1 - 1.6 7.1 3.8 2.6 6.4 3.8 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Ribosomal_60s PF00428.19 GAP93007.1 - 6.2 7.5 16.5 0.35 11.5 9.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein MSA-2c PF12238.8 GAP93008.1 - 0.014 15.4 0.3 0.019 15.0 0.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pal1 PF08316.11 GAP93009.1 - 1.6e-47 161.7 1.2 4e-47 160.4 1.2 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein SUIM_assoc PF16619.5 GAP93010.1 - 0.21 11.7 8.2 0.75 9.9 8.2 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Fasciclin PF02469.22 GAP93011.1 - 7.4e-39 132.9 0.0 3.9e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Abhydrolase_1 PF00561.20 GAP93013.1 - 1.4e-45 155.9 0.0 5.7e-45 154.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 GAP93013.1 - 0.0063 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase SAD_SRA PF02182.17 GAP93014.1 - 4.9e-39 133.5 0.0 6.8e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain NAD_binding_2 PF03446.15 GAP93015.1 - 1.7e-29 103.0 0.5 3e-29 102.2 0.5 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 GAP93015.1 - 8.2e-09 35.8 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 GAP93015.1 - 1.3e-06 28.9 0.3 4.2e-06 27.2 0.3 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 GAP93015.1 - 0.00027 20.3 0.0 0.00056 19.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 GAP93015.1 - 0.00037 20.6 0.0 0.0007 19.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.9 GAP93015.1 - 0.006 16.4 3.5 0.006 16.4 3.5 2.5 2 2 1 3 3 3 1 Rossmann-like domain DFP PF04127.15 GAP93016.1 - 8.8e-14 51.8 0.0 8.6e-06 25.7 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.16 GAP93017.1 - 6.7e-41 140.4 66.6 2.6e-36 125.3 44.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP93017.1 - 0.0016 17.3 35.9 0.011 14.6 16.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Wbp11 PF09429.10 GAP93018.1 - 5.9e-23 81.1 6.5 5.9e-23 81.1 6.5 1.8 2 0 0 2 2 2 1 WW domain binding protein 11 Pkinase PF00069.25 GAP93019.1 - 1.1e-60 205.2 0.0 8.7e-60 202.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP93019.1 - 3.9e-28 98.5 0.6 9.3e-20 71.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 GAP93019.1 - 0.00074 20.2 2.3 0.0011 19.7 0.6 2.2 2 1 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.23 GAP93019.1 - 0.0022 18.0 0.4 0.15 12.0 0.0 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 GAP93019.1 - 0.0062 15.5 0.0 0.0097 14.9 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 GAP93019.1 - 0.0062 15.9 0.1 0.023 14.0 0.0 1.9 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 GAP93019.1 - 0.04 13.3 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 GAP93019.1 - 0.18 10.9 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 CFEM PF05730.11 GAP93020.1 - 0.0017 18.4 2.0 0.0034 17.4 2.0 1.5 1 0 0 1 1 1 1 CFEM domain WSC PF01822.19 GAP93021.1 - 4.5e-10 39.6 8.3 9e-10 38.6 8.3 1.5 1 0 0 1 1 1 1 WSC domain Adeno_E3_CR2 PF02439.15 GAP93021.1 - 0.003 17.3 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Herpes_gE PF02480.16 GAP93021.1 - 0.19 10.5 0.4 0.35 9.6 0.4 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E GATA PF00320.27 GAP93022.1 - 3.1e-15 55.5 4.1 6.8e-15 54.4 4.1 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 GAP93022.1 - 7.8e-10 38.4 0.4 1.5e-09 37.5 0.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pyrid_oxidase_2 PF13883.6 GAP93023.1 - 1.4e-32 113.0 0.0 2.7e-31 108.8 0.0 2.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FAD_binding_2 PF00890.24 GAP93023.1 - 0.074 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Acatn PF13000.7 GAP93024.1 - 4.9e-166 553.5 18.1 2.8e-82 277.0 7.8 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 GAP93024.1 - 0.004 16.1 4.9 0.004 16.1 4.9 2.0 2 0 0 2 2 2 1 MFS_1 like family CENP-O PF09496.10 GAP93025.1 - 1.2e-72 244.3 0.3 7.4e-72 241.8 0.0 1.9 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component TolA_bind_tri PF16331.5 GAP93025.1 - 0.038 14.1 0.7 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation HAUS5 PF14817.6 GAP93025.1 - 0.065 12.0 2.0 0.093 11.5 2.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 HalX PF08663.10 GAP93025.1 - 1.9 8.9 5.0 5.1 7.5 0.3 2.8 3 0 0 3 3 3 0 HalX domain Abhydrolase_6 PF12697.7 GAP93026.1 - 7.2e-12 46.4 3.6 9.7e-12 45.9 3.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP93026.1 - 1.1e-09 38.3 0.1 2.3e-09 37.3 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP93026.1 - 0.051 12.8 0.1 0.14 11.4 0.1 1.8 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Amidase PF01425.21 GAP93027.1 - 0.043 12.8 0.1 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 Amidase DUF885 PF05960.11 GAP93027.1 - 0.095 12.3 0.0 0.77 9.3 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) p450 PF00067.22 GAP93028.1 - 9.4e-25 87.3 0.0 1e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 GAP93030.1 - 4.3e-12 45.5 0.0 3.1e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF2790 PF10976.8 GAP93030.1 - 0.082 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) Glyco_hydro_18 PF00704.28 GAP93031.1 - 9.9e-59 199.6 3.5 1.2e-58 199.3 2.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DNase_NucA_NucB PF14040.6 GAP93031.1 - 0.052 13.9 0.7 0.2 12.0 0.7 2.0 1 1 0 1 1 1 0 Deoxyribonuclease NucA/NucB LysM PF01476.20 GAP93032.1 - 2.9e-09 36.8 0.0 0.00065 19.7 0.0 3.1 3 0 0 3 3 3 2 LysM domain LysM PF01476.20 GAP93034.1 - 6.5e-20 70.9 0.1 4.7e-05 23.4 0.0 4.2 4 0 0 4 4 4 4 LysM domain HAP2-GCS1 PF10699.9 GAP93034.1 - 0.0042 17.0 2.4 0.41 10.7 0.1 3.5 3 0 0 3 3 3 1 Male gamete fusion factor SapB_2 PF03489.17 GAP93034.1 - 0.038 14.1 0.1 5.2 7.3 0.1 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 2 Como_LCP PF02247.16 GAP93034.1 - 0.16 10.6 5.6 2.1 6.9 0.1 3.0 3 0 0 3 3 3 0 Large coat protein Rubella_E2 PF05749.11 GAP93034.1 - 0.19 11.2 24.6 0.035 13.6 5.5 2.8 1 1 2 3 3 3 0 Rubella membrane glycoprotein E2 Sporozoite_P67 PF05642.11 GAP93034.1 - 4.8 5.1 15.8 0.86 7.6 6.6 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Mucin PF01456.17 GAP93034.1 - 5.6 7.0 39.8 0.37 10.8 5.9 3.0 3 0 0 3 3 3 0 Mucin-like glycoprotein MGC-24 PF05283.11 GAP93034.1 - 6 7.3 14.3 5.5 7.4 4.6 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Sugar_tr PF00083.24 GAP93035.1 - 2.7e-106 356.1 20.7 3.2e-106 355.9 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP93035.1 - 3.6e-20 72.2 41.5 7.7e-15 54.7 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 GAP93035.1 - 0.0041 15.7 2.1 0.0041 15.7 2.1 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Glyco_hydro_115 PF15979.5 GAP93036.1 - 2.3e-129 431.7 0.1 3.1e-129 431.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 GAP93036.1 - 8.1e-41 139.7 0.0 1.5e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Ribonuclease PF00545.20 GAP93037.1 - 3.2e-08 34.2 0.0 4.8e-08 33.6 0.0 1.3 1 1 0 1 1 1 1 ribonuclease WD40 PF00400.32 GAP93038.1 - 5.1e-38 128.4 23.3 1.8e-08 34.9 0.8 10.5 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP93038.1 - 8.4e-17 61.3 0.1 0.0026 18.0 0.0 7.8 5 1 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT_N PF17100.5 GAP93038.1 - 1.4e-13 51.3 1.0 2.6e-12 47.1 1.0 2.5 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 GAP93038.1 - 1.6e-08 34.7 0.0 7.3e-07 29.2 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Ge1_WD40 PF16529.5 GAP93038.1 - 5e-07 29.0 0.1 0.0002 20.4 0.0 3.4 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 GAP93038.1 - 0.004 15.9 0.2 1.4 7.4 0.0 2.6 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 GAP93038.1 - 0.061 13.8 0.3 25 5.5 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Nucleoporin_N PF08801.11 GAP93038.1 - 0.079 11.7 0.3 1 8.0 0.0 2.8 3 1 0 3 3 3 0 Nup133 N terminal like CPSF_A PF03178.15 GAP93038.1 - 0.11 11.9 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 CPSF A subunit region Sigma70_ner PF04546.13 GAP93039.1 - 0.055 13.3 1.8 0.081 12.8 1.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RNase_H2_suC PF08615.11 GAP93039.1 - 0.078 13.1 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SDA1 PF05285.12 GAP93039.1 - 0.41 10.0 8.7 0.71 9.2 8.7 1.3 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 GAP93039.1 - 1.9 6.9 6.9 3.5 6.1 6.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 GAP93039.1 - 2.7 6.1 10.0 3.7 5.6 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 GAP93039.1 - 9.4 4.4 7.6 14 3.8 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein adh_short_C2 PF13561.6 GAP93040.1 - 5.5e-37 127.6 7.3 3.2e-18 66.1 8.1 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP93040.1 - 4.5e-35 120.9 9.5 1.2e-32 113.0 9.5 2.8 1 1 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 GAP93040.1 - 0.00079 19.3 1.9 0.0014 18.6 1.9 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mucin PF01456.17 GAP93040.1 - 0.05 13.6 0.5 0.1 12.6 0.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein PLU-1 PF08429.11 GAP93041.1 - 3.3e-113 378.3 8.5 6.9e-110 367.4 7.6 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 GAP93041.1 - 2e-42 144.2 0.4 5.3e-42 142.9 0.4 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 GAP93041.1 - 3.4e-22 78.9 0.0 1e-21 77.4 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 GAP93041.1 - 4.8e-18 64.8 33.2 8.4e-11 41.6 4.4 4.2 4 0 0 4 4 4 2 PHD-finger JmjN PF02375.17 GAP93041.1 - 2e-15 56.4 0.3 5e-15 55.2 0.3 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 GAP93041.1 - 1.1e-11 44.9 6.2 2.9e-11 43.6 6.2 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 GAP93041.1 - 0.029 14.0 8.7 0.09 12.4 1.4 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DUF445 PF04286.12 GAP93041.1 - 0.095 12.5 0.5 0.3 10.9 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PHD_2 PF13831.6 GAP93041.1 - 1.7 8.3 10.9 0.081 12.5 1.1 2.8 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 GAP93041.1 - 2.2 8.4 16.8 15 5.7 5.9 4.0 3 1 0 3 3 3 0 KIAA1045 RING finger GIY-YIG PF01541.24 GAP93042.1 - 1.2e-11 44.8 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 GAP93042.1 - 0.004 17.4 0.3 0.0074 16.5 0.3 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain FANCL_C PF11793.8 GAP93042.1 - 0.0044 17.2 0.6 0.0073 16.5 0.6 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 GAP93042.1 - 0.0094 16.1 0.1 0.016 15.4 0.1 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain T5orf172 PF10544.9 GAP93042.1 - 0.082 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 T5orf172 domain DUF5488 PF17590.2 GAP93042.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5488) Prok-RING_1 PF14446.6 GAP93042.1 - 0.18 11.8 2.5 0.19 11.6 0.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 GAP93042.1 - 0.29 11.1 1.9 0.54 10.2 1.9 1.5 1 0 0 1 1 1 0 PHD-finger DUF3449 PF11931.8 GAP93043.1 - 4.2e-79 264.6 2.1 9.4e-79 263.5 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 GAP93043.1 - 1.4e-21 76.8 2.6 2.5e-21 76.0 0.6 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 GAP93043.1 - 9.4e-13 47.8 0.0 2.1e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 GAP93043.1 - 2.4e-11 43.6 2.3 2.1e-09 37.4 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 GAP93043.1 - 4.7e-09 36.3 0.3 4.7e-09 36.3 0.3 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 GAP93043.1 - 0.0024 18.1 3.7 0.015 15.6 0.6 2.8 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) PRP9_N PF16958.5 GAP93043.1 - 0.0037 17.3 2.2 0.051 13.6 0.4 3.7 3 1 1 4 4 4 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_4 PF13894.6 GAP93043.1 - 0.036 14.9 0.5 5.1 8.2 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.12 GAP93043.1 - 0.095 12.5 0.4 0.24 11.2 0.4 1.6 1 0 0 1 1 1 0 U1 zinc finger DUF4674 PF15719.5 GAP93043.1 - 1.3 9.1 5.5 0.73 9.8 3.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) zf-DBF PF07535.12 GAP93043.1 - 3.1 8.0 7.6 0.22 11.7 0.3 2.6 2 1 0 2 2 2 0 DBF zinc finger DEAD PF00270.29 GAP93044.1 - 1.2e-42 145.7 0.2 1.9e-42 145.0 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 GAP93044.1 - 2.5e-33 114.7 0.0 9.7e-33 112.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 GAP93044.1 - 0.00049 19.9 0.1 0.00074 19.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 GAP93044.1 - 0.00096 19.2 0.0 0.0019 18.2 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 GAP93044.1 - 0.0014 19.0 0.1 0.011 16.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 GAP93044.1 - 0.032 14.2 0.5 0.14 12.1 0.2 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 GAP93044.1 - 0.052 13.4 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase TniB PF05621.11 GAP93044.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DUF5393 PF17371.2 GAP93044.1 - 0.077 11.1 0.1 0.12 10.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) AAA_22 PF13401.6 GAP93044.1 - 0.19 12.0 0.8 0.83 9.9 0.8 2.0 1 1 0 1 1 1 0 AAA domain Cutinase PF01083.22 GAP93045.1 - 2.9e-54 183.7 7.3 2.9e-54 183.7 7.3 1.4 2 0 0 2 2 2 1 Cutinase CBM_1 PF00734.18 GAP93045.1 - 3.8e-10 39.5 18.8 3.8e-10 39.5 18.8 4.2 5 2 0 5 5 5 1 Fungal cellulose binding domain PE-PPE PF08237.11 GAP93045.1 - 5.4e-05 22.9 0.2 7.9e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 GAP93045.1 - 0.11 13.1 0.1 0.14 12.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_11 PF00457.17 GAP93046.1 - 5.8e-80 267.1 16.7 7.9e-80 266.7 16.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 GAP93046.1 - 7e-11 41.9 19.0 2.4e-10 40.2 19.0 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Tannase PF07519.11 GAP93047.1 - 7.8e-98 328.4 1.6 2.4e-95 320.2 1.6 2.1 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 GAP93047.1 - 0.00066 19.2 0.3 0.69 9.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 GAP93047.1 - 0.13 11.5 0.1 0.28 10.4 0.1 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_hydro_61 PF03443.14 GAP93048.1 - 1.4e-67 227.6 0.0 1.4e-67 227.6 0.0 2.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 GAP93048.1 - 1e-11 44.6 10.6 2.6e-11 43.3 10.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Serglycin PF04360.12 GAP93048.1 - 0.015 15.2 0.9 0.027 14.4 0.9 1.4 1 0 0 1 1 1 0 Serglycin Mitofilin PF09731.9 GAP93048.1 - 0.31 9.8 6.2 0.41 9.4 6.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SOG2 PF10428.9 GAP93048.1 - 3 6.9 18.3 4.3 6.4 18.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mito_carr PF00153.27 GAP93049.1 - 2.5e-14 52.9 1.4 0.00022 21.1 0.1 5.1 4 1 0 4 4 4 4 Mitochondrial carrier protein AP_endonuc_2 PF01261.24 GAP93050.1 - 2.4e-08 33.7 0.0 6.9e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel ADH_N PF08240.12 GAP93051.1 - 2.3e-28 98.2 0.1 4.7e-28 97.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP93051.1 - 3.7e-09 36.6 0.3 7.9e-09 35.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 GAP93051.1 - 6.8e-07 29.1 0.4 1.4e-06 28.1 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 GAP93051.1 - 0.00024 20.6 0.1 0.00056 19.5 0.0 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 GAP93051.1 - 0.003 16.3 0.2 0.0041 15.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 GAP93051.1 - 0.003 16.9 0.4 0.0054 16.1 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 GAP93051.1 - 0.034 13.4 0.1 0.053 12.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 GAP93051.1 - 0.095 12.3 0.4 0.16 11.5 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP93051.1 - 0.096 11.8 0.8 0.13 11.3 0.6 1.4 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 GAP93051.1 - 0.12 13.0 0.3 0.86 10.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 GAP93052.1 - 1.3e-12 48.9 0.6 1.6e-12 48.5 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 GAP93052.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.12 GAP93052.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 GAP93052.1 - 0.072 12.4 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 GAP93052.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.14 GAP93052.1 - 0.15 11.6 0.1 0.42 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Ank_2 PF12796.7 GAP93053.1 - 4.7e-27 94.4 0.0 4.1e-14 52.9 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Pkinase PF00069.25 GAP93053.1 - 2.9e-26 92.4 0.0 5.1e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP93053.1 - 6.2e-16 58.5 0.0 1.6e-15 57.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_5 PF13857.6 GAP93053.1 - 1.5e-13 50.6 0.1 3.9e-06 27.0 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAP93053.1 - 4.2e-12 46.3 0.0 5e-07 30.1 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 GAP93053.1 - 2.3e-11 43.6 0.1 0.0044 17.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 GAP93053.1 - 1.8e-09 37.0 0.0 0.0041 17.5 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Patatin PF01734.22 GAP93053.1 - 0.0014 18.8 0.1 0.017 15.3 0.2 2.6 3 1 0 3 3 3 1 Patatin-like phospholipase Lipoxygenase PF00305.19 GAP93054.1 - 1.3e-26 93.3 0.0 1.9e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase Peroxidase_2 PF01328.17 GAP93055.1 - 3e-30 106.2 0.1 4e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 4HBT_2 PF13279.6 GAP93056.1 - 8.3e-07 29.5 0.0 1e-06 29.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.16 GAP93057.1 - 4.5e-28 98.2 39.6 4.5e-28 98.2 39.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily HlyIII PF03006.20 GAP93058.1 - 2.3e-47 161.6 15.7 2.7e-47 161.4 15.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related SPW PF03779.14 GAP93058.1 - 0.08 12.5 0.4 0.08 12.5 0.4 2.2 2 0 0 2 2 2 0 SPW repeat p450 PF00067.22 GAP93059.1 - 3.4e-62 210.7 0.0 4.6e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 GAP93059.1 - 0.027 14.2 0.4 0.075 12.8 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) PNP_UDP_1 PF01048.20 GAP93060.1 - 2.8e-12 46.4 0.5 1.6e-11 44.0 0.2 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 GAP93061.1 - 1.5e-19 70.5 0.1 2.6e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 GAP93061.1 - 1.2e-16 60.8 12.7 9.5e-08 32.6 0.3 7.2 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP93061.1 - 8.2e-08 32.4 0.2 0.47 10.8 0.0 6.7 4 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 GAP93061.1 - 1.6e-05 24.7 0.1 0.92 9.5 0.0 4.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 GAP93061.1 - 8.2e-05 23.1 0.0 0.00023 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 GAP93061.1 - 0.029 14.7 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 GAP93061.1 - 0.091 12.3 0.0 0.33 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAP93061.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 GAP93061.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 GAP93061.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Proteasome_A_N PF10584.9 GAP93061.1 - 0.27 11.0 4.6 2 8.2 0.1 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature HGTP_anticodon PF03129.20 GAP93062.1 - 8.3e-20 70.8 0.0 2.7e-19 69.1 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 GAP93062.1 - 3.5e-09 36.9 0.0 1.8e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_hyd_65N_2 PF14498.6 GAP93063.1 - 4e-53 180.7 0.1 5.8e-53 180.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DJ-1_PfpI PF01965.24 GAP93063.1 - 1e-12 48.2 0.0 2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family PHO4 PF01384.20 GAP93064.1 - 2.2e-115 385.3 16.2 2.6e-115 385.1 16.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.10 GAP93064.1 - 0.15 11.9 0.2 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain VirB3 PF05101.13 GAP93064.1 - 1.1 9.5 10.5 5.4 7.3 5.8 3.5 2 1 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein FAD_binding_4 PF01565.23 GAP93065.1 - 5.2e-15 55.4 7.5 1.2e-14 54.2 7.5 1.7 1 0 0 1 1 1 1 FAD binding domain P-mevalo_kinase PF04275.14 GAP93065.1 - 1.2e-13 51.0 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase Pribosyltran PF00156.27 GAP93065.1 - 1.9e-13 50.3 0.1 3.8e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Methyltransf_23 PF13489.6 GAP93065.1 - 4.4e-06 26.6 0.0 2.6e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain UPRTase PF14681.6 GAP93065.1 - 0.0014 18.1 0.0 0.0041 16.6 0.0 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase GHMP_kinases_C PF08544.13 GAP93065.1 - 0.092 13.1 0.0 0.4 11.1 0.0 2.1 1 0 0 1 1 1 0 GHMP kinases C terminal CENP-B_dimeris PF09026.10 GAP93065.1 - 0.2 12.1 4.0 0.44 10.9 4.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Yeast-kill-tox PF09207.11 GAP93065.1 - 0.78 10.4 3.2 0.58 10.8 0.2 2.2 2 0 0 2 2 2 0 Yeast killer toxin Caskin-Pro-rich PF16907.5 GAP93066.1 - 0.2 12.2 0.2 0.2 12.2 0.2 3.5 3 1 0 3 3 3 0 Proline rich region of Caskin proteins Rhomboid PF01694.22 GAP93067.1 - 5.2e-32 110.9 10.5 5.2e-32 110.9 10.5 2.0 2 0 0 2 2 2 1 Rhomboid family DUF4381 PF14316.6 GAP93067.1 - 0.14 12.4 1.5 0.27 11.5 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2177 PF09945.9 GAP93067.1 - 1.5 8.9 8.6 0.77 9.9 0.6 3.3 4 0 0 4 4 4 0 Predicted membrane protein (DUF2177) XPB_DRD PF18458.1 GAP93069.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain Cnd3 PF12719.7 GAP93070.1 - 1.1e-92 310.3 0.2 5.2e-92 308.2 0.1 2.2 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 GAP93070.1 - 1.4e-10 41.4 10.2 6.2e-06 26.5 2.1 5.2 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 GAP93070.1 - 1.9e-07 30.7 11.0 0.29 11.5 0.0 7.4 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 GAP93070.1 - 0.005 16.9 6.7 0.22 11.5 0.0 4.8 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 GAP93070.1 - 0.0056 16.3 1.0 0.64 9.5 0.0 3.4 4 1 1 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 GAP93070.1 - 0.043 14.3 8.8 1.7 9.2 0.2 5.3 6 1 0 6 6 6 0 HEAT-like repeat Adaptin_N PF01602.20 GAP93070.1 - 0.045 12.3 0.3 0.23 9.9 0.0 2.3 2 1 1 3 3 3 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 GAP93070.1 - 0.067 13.8 0.0 0.99 10.0 0.0 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region MDM31_MDM32 PF08118.11 GAP93070.1 - 0.26 9.9 1.0 0.5 9.0 1.0 1.3 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins IFRD PF05004.13 GAP93070.1 - 0.58 9.2 10.1 3.9 6.5 0.0 4.6 3 1 2 5 5 5 0 Interferon-related developmental regulator (IFRD) RRM_1 PF00076.22 GAP93071.1 - 2.6e-58 193.7 0.0 2.6e-19 68.8 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 GAP93071.1 - 7.9e-05 22.3 0.0 0.034 13.8 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 GAP93071.1 - 0.0014 18.5 4.6 0.39 10.5 0.1 3.4 3 1 1 4 4 4 2 Rrp7 RRM-like N-terminal domain CENP-B_dimeris PF09026.10 GAP93071.1 - 0.0016 18.8 1.9 0.0016 18.8 1.9 3.5 1 1 2 3 3 3 1 Centromere protein B dimerisation domain DUF2457 PF10446.9 GAP93071.1 - 1.1 8.3 27.2 2.7 7.1 27.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SAPS PF04499.15 GAP93071.1 - 1.2 7.8 7.4 1.9 7.2 7.4 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 GAP93071.1 - 3.4 6.6 6.7 7.5 5.4 6.7 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 GAP93071.1 - 4.6 6.6 32.8 0.39 10.1 25.9 2.5 2 0 0 2 2 2 0 SDA1 tRNA-synt_2b PF00587.25 GAP93073.1 - 1.2e-30 106.8 0.0 1.7e-28 99.8 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 GAP93073.1 - 1.9e-13 50.4 0.0 3.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 GAP93073.1 - 1.3e-12 47.6 0.0 2.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 GAP93073.1 - 4.4e-12 45.9 0.0 9.1e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain Rax2 PF12768.7 GAP93074.1 - 0.0022 17.5 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity PX PF00787.24 GAP93075.1 - 4.3e-13 49.2 0.0 8.1e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 PX domain AltA1 PF16541.5 GAP93076.1 - 1.2e-26 93.7 3.0 1.8e-26 93.1 3.0 1.3 1 0 0 1 1 1 1 Alternaria alternata allergen 1 PhoLip_ATPase_C PF16212.5 GAP93077.1 - 2.4e-64 217.5 9.1 3.5e-64 217.0 9.1 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase_3 PF08282.12 GAP93077.1 - 0.0092 15.8 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 GAP93077.1 - 0.078 13.3 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 GAP93077.1 - 9 6.4 7.9 1.9 8.5 3.7 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PhoLip_ATPase_N PF16209.5 GAP93078.1 - 1.8e-24 85.2 0.0 2.6e-23 81.5 0.1 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 GAP93078.1 - 1e-13 51.2 0.1 2e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 GAP93078.1 - 3.4e-13 49.5 0.0 7.3e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Homeodomain PF00046.29 GAP93080.1 - 6.5e-20 70.7 5.3 1.4e-19 69.7 5.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 GAP93080.1 - 0.0047 16.8 0.5 0.0047 16.8 0.5 2.1 2 0 0 2 2 2 1 Homeobox KN domain MIP-T3_C PF17749.1 GAP93080.1 - 0.08 12.9 3.1 0.13 12.2 3.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Tho2 PF11262.8 GAP93080.1 - 0.65 9.1 3.6 0.95 8.6 3.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ADH_N PF08240.12 GAP93081.1 - 1.3e-07 31.4 0.0 3.5e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP93081.1 - 8.9e-06 25.7 1.8 1.9e-05 24.6 1.7 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase eIF2_C PF09173.11 GAP93082.1 - 3.4e-34 116.9 0.4 8.7e-34 115.6 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 GAP93082.1 - 5.1e-22 78.4 2.3 7.1e-21 74.6 2.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 GAP93082.1 - 7.5e-10 39.1 0.2 1.7e-09 37.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 GAP93082.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 GAP93082.1 - 0.0081 16.1 0.4 0.075 12.9 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 GAP93082.1 - 0.042 13.9 0.4 0.042 13.9 0.4 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain FAP PF07174.11 GAP93082.1 - 2.1 7.7 8.9 0.36 10.2 5.1 1.6 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Cofilin_ADF PF00241.20 GAP93083.1 - 6.6e-20 71.1 0.0 7.7e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cupin_2 PF07883.11 GAP93084.1 - 1.9e-11 43.5 0.8 2.7e-11 43.0 0.8 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 GAP93084.1 - 1.6e-06 27.8 0.2 1.9e-06 27.6 0.2 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 GAP93084.1 - 0.0064 16.2 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 GAP93084.1 - 0.013 15.3 0.3 0.02 14.6 0.3 1.4 1 1 0 1 1 1 0 Cupin Adaptin_binding PF10199.9 GAP93085.1 - 3.4e-11 43.8 4.0 8.1e-11 42.6 4.0 1.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Bac_rhamnosid6H PF17389.2 GAP93086.1 - 4.8e-116 387.7 1.8 6.6e-116 387.3 1.8 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 GAP93086.1 - 5.7e-58 195.5 0.1 9.9e-58 194.8 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 GAP93086.1 - 8.1e-32 109.2 0.0 1.5e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 GAP93086.1 - 1.8e-21 75.7 0.2 6.8e-21 73.9 0.1 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain FAD_binding_3 PF01494.19 GAP93088.1 - 6.1e-26 91.5 1.2 3.4e-25 89.0 1.2 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP93088.1 - 2.1e-07 30.9 0.7 1.1e-05 25.2 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 GAP93088.1 - 8.5e-06 25.2 0.5 7.5e-05 22.1 0.5 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP93088.1 - 1.2e-05 25.4 0.7 3e-05 24.2 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 GAP93088.1 - 0.0001 21.1 0.2 0.02 13.6 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 GAP93088.1 - 0.00019 21.9 0.1 0.0013 19.3 0.2 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAP93088.1 - 0.00072 18.5 2.5 0.45 9.3 0.4 2.1 1 1 1 2 2 2 2 Tryptophan halogenase AlaDh_PNT_C PF01262.21 GAP93088.1 - 0.0016 17.8 0.1 0.0026 17.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 GAP93088.1 - 0.0019 17.5 0.2 0.0033 16.7 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP93088.1 - 0.0029 16.8 0.1 0.004 16.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 GAP93088.1 - 0.014 15.1 0.1 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 GAP93088.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 GAP93088.1 - 0.026 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 GAP93088.1 - 0.03 14.8 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 GAP93088.1 - 0.036 13.7 0.1 0.063 12.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 GAP93088.1 - 0.047 13.0 0.5 0.08 12.3 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 GAP93088.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 GAP93088.1 - 0.073 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 GAP93089.1 - 3e-21 75.6 1.4 5.9e-21 74.7 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP93089.1 - 9.5e-06 25.6 0.0 2.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like UbiA PF01040.18 GAP93090.1 - 3.4e-34 118.3 20.9 4.9e-34 117.8 20.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_4 PF01565.23 GAP93091.1 - 3.8e-27 94.7 1.5 6e-27 94.1 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP93091.1 - 1.5e-06 28.2 1.2 2.5e-06 27.5 0.3 1.9 2 0 0 2 2 2 1 Berberine and berberine like GMC_oxred_N PF00732.19 GAP93093.1 - 9.5e-37 127.0 0.0 8.1e-36 123.9 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP93093.1 - 4.2e-33 114.9 0.0 6.1e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAP93093.1 - 0.04 13.0 0.2 4.3 6.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain UCR_Fe-S_N PF10399.9 GAP93093.1 - 0.063 12.6 0.3 0.15 11.4 0.3 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Dyp_perox PF04261.12 GAP93094.1 - 3.6e-86 289.1 0.0 4.2e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Fungal_trans_2 PF11951.8 GAP93095.1 - 2.6e-18 66.0 0.4 4.2e-18 65.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sel_put PF04328.13 GAP93098.1 - 1.3 9.1 4.0 3.6 7.7 4.0 1.7 1 0 0 1 1 1 0 Selenoprotein, putative Ctr PF04145.15 GAP93100.1 - 0.028 15.1 0.0 0.91 10.1 0.0 2.4 2 0 0 2 2 2 0 Ctr copper transporter family DUF551 PF04448.12 GAP93100.1 - 0.11 13.4 0.0 0.39 11.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF551) ketoacyl-synt PF00109.26 GAP93101.1 - 3.1e-71 239.9 0.1 6e-71 239.0 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP93101.1 - 1.1e-51 175.3 0.1 2.3e-51 174.2 0.1 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 GAP93101.1 - 9e-42 143.7 0.2 1.7e-41 142.8 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP93101.1 - 5.2e-30 103.9 0.0 1.3e-29 102.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 GAP93101.1 - 1e-25 90.6 0.4 4e-25 88.7 0.6 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 GAP93101.1 - 1.9e-17 63.8 0.0 5.1e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP93101.1 - 1.2e-13 51.5 0.0 3e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP93101.1 - 1.4e-13 51.4 0.0 4.2e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAP93101.1 - 1e-12 48.5 0.0 3.1e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAP93101.1 - 7.2e-12 45.2 0.0 9e-11 41.6 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 GAP93101.1 - 1.4e-11 44.5 0.0 3.2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.22 GAP93101.1 - 1.5e-10 40.4 0.0 9.6e-05 21.3 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 Methyltransf_31 PF13847.6 GAP93101.1 - 5.8e-08 32.7 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_4 PF07993.12 GAP93101.1 - 1e-05 24.8 0.0 0.0002 20.6 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein adh_short_C2 PF13561.6 GAP93101.1 - 1.5e-05 24.7 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 GAP93101.1 - 0.0002 20.8 0.1 0.00041 19.8 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 GAP93101.1 - 0.0013 18.1 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 GAP93101.1 - 0.01 16.2 0.3 0.027 14.8 0.3 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site ACP_syn_III PF08545.10 GAP93101.1 - 2 8.3 4.2 17 5.3 2.6 3.2 2 1 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HNH_2 PF13391.6 GAP93102.1 - 7e-16 58.1 2.0 7.6e-16 58.0 0.1 2.1 3 0 0 3 3 3 1 HNH endonuclease HNH_4 PF13395.6 GAP93102.1 - 0.078 12.9 0.2 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 HNH endonuclease DUF4744 PF15918.5 GAP93104.1 - 0.96 10.3 78.6 6.6 7.7 20.6 5.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4744) HET PF06985.11 GAP93106.1 - 9.6e-28 97.4 0.2 3.4e-27 95.6 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Colicin_D PF11429.8 GAP93107.1 - 0.066 13.7 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Colicin D Glyco_hydro_cc PF11790.8 GAP93108.1 - 2.1e-22 79.9 0.3 2.6e-22 79.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Vps54 PF07928.12 GAP93109.1 - 1e-50 171.7 0.6 3.4e-50 169.9 0.1 2.2 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 GAP93109.1 - 4.4e-09 36.0 0.8 1.4e-08 34.4 0.8 1.8 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF3490 PF11995.8 GAP93109.1 - 0.0002 21.2 3.8 0.063 13.1 0.2 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3490) DUF2451 PF10474.9 GAP93109.1 - 0.11 12.3 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.11 GAP93109.1 - 3.9 7.6 5.2 1.2 9.2 0.5 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MCM PF00493.23 GAP93110.1 - 9.6e-105 348.6 0.1 2.2e-104 347.4 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 GAP93110.1 - 5.3e-36 123.2 0.2 1e-35 122.3 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 GAP93110.1 - 3.2e-28 98.0 0.8 7.8e-28 96.7 0.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 GAP93110.1 - 1e-14 55.0 0.6 2.3e-14 53.8 0.6 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 GAP93110.1 - 2.1e-06 27.3 0.0 0.00016 21.1 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 GAP93110.1 - 1.7e-05 24.9 0.0 3.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 GAP93110.1 - 0.00035 20.4 0.1 0.0013 18.6 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 GAP93110.1 - 0.013 15.9 0.1 0.15 12.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 GAP93110.1 - 0.051 13.3 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain GntR PF00392.21 GAP93110.1 - 0.2 11.4 0.6 0.6 9.8 0.6 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family AMP-binding PF00501.28 GAP93111.1 - 8.9e-19 67.4 0.1 1.5e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Aldedh PF00171.22 GAP93112.1 - 6.5e-154 512.8 0.1 7.4e-154 512.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 GAP93113.1 - 3.3e-16 59.1 0.3 2.2e-15 56.4 0.4 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP93113.1 - 1.2e-07 31.7 9.7 2.1e-07 31.0 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.24 GAP93114.1 - 8.1e-52 177.0 0.0 9.7e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAP93114.1 - 2.9e-15 56.3 0.1 7.3e-15 55.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 GAP93114.1 - 1.1e-08 34.8 0.1 1.5e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP93114.1 - 1.7e-07 30.7 2.9 3.1e-07 29.8 2.9 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 GAP93114.1 - 8.3e-07 28.9 2.9 1.4e-06 28.1 2.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAP93114.1 - 3.4e-06 26.5 0.4 5.6e-06 25.8 0.4 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 GAP93114.1 - 4e-06 25.8 0.6 7.1e-06 25.0 0.5 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAP93114.1 - 5.7e-05 22.5 0.1 9.4e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP93114.1 - 0.00033 19.9 1.3 0.00053 19.2 1.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 GAP93114.1 - 0.0004 19.7 0.2 0.0093 15.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP93114.1 - 0.00058 20.4 0.2 0.0015 19.1 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 GAP93114.1 - 0.0016 17.6 1.1 0.0062 15.6 0.9 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 GAP93114.1 - 0.0027 17.0 0.3 0.0042 16.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 GAP93114.1 - 0.0035 16.7 0.5 0.0064 15.8 0.5 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 GAP93114.1 - 0.0086 16.0 0.4 0.016 15.1 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glycoamylase PF10091.9 GAP93115.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative glucoamylase 2OG-FeII_Oxy_3 PF13640.6 GAP93115.1 - 0.1 13.5 0.0 0.17 12.8 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 GAP93116.1 - 0.034 15.0 0.0 0.1 13.5 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily AA_permease PF00324.21 GAP93117.1 - 3.1e-94 316.3 38.1 3.7e-94 316.0 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP93117.1 - 2.4e-22 79.4 43.5 2.8e-22 79.2 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease NPCC PF08058.11 GAP93119.1 - 2.8e-09 37.1 0.0 3.2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex component DNA_binding_1 PF01035.20 GAP93121.1 - 2.1e-30 104.7 0.0 3.7e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain MFS_1 PF07690.16 GAP93123.1 - 5.3e-15 55.2 16.4 1.7e-14 53.5 16.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP93123.1 - 1.2e-07 30.9 2.4 1.2e-07 30.9 2.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter ubiquitin PF00240.23 GAP93124.1 - 0.028 14.2 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family DUF629 PF04780.12 GAP93125.1 - 0.00036 19.2 1.8 0.00036 19.2 1.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.6 GAP93125.1 - 0.008 16.6 6.7 4.9 7.7 0.3 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP93125.1 - 0.0099 16.6 18.7 1.1 10.2 1.5 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 GAP93125.1 - 0.011 16.0 2.7 0.057 13.7 0.2 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DTHCT PF08070.11 GAP93125.1 - 0.034 14.9 2.2 0.034 14.9 2.2 2.3 2 0 0 2 2 2 0 DTHCT (NUC029) region zf-C2H2 PF00096.26 GAP93125.1 - 2.6 8.7 19.2 2.4 8.8 1.5 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 GAP93125.1 - 3.1 8.2 13.6 7.3 7.0 1.7 3.7 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding TFB6 PF17110.5 GAP93125.1 - 3.4 7.4 6.1 14 5.4 0.2 3.1 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH HEPN_AbiU2 PF18734.1 GAP93125.1 - 9.3 5.7 8.2 0.68 9.4 0.4 2.5 3 0 0 3 3 3 0 AbiU2 HeLo PF14479.6 GAP93126.1 - 0.028 14.3 0.5 1 9.1 0.1 2.9 2 1 0 2 2 2 0 Prion-inhibition and propagation Vac_Fusion PF02346.16 GAP93126.1 - 0.81 9.4 3.3 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF4232 PF14016.6 GAP93127.1 - 0.12 12.5 15.6 1.1 9.4 0.9 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF4232) Big_9 PF17963.1 GAP93127.1 - 0.63 10.8 5.0 1.4 9.7 0.1 3.5 3 0 0 3 3 3 0 Bacterial Ig domain Nop PF01798.18 GAP93128.1 - 4.2e-79 265.3 1.6 8.2e-79 264.3 0.1 2.3 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 GAP93128.1 - 2.4e-20 72.7 0.6 7.3e-20 71.1 0.6 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain AAA_assoc PF14363.6 GAP93128.1 - 0.13 12.6 0.1 0.65 10.4 0.0 2.3 3 0 0 3 3 3 0 Domain associated at C-terminal with AAA vATP-synt_AC39 PF01992.16 GAP93129.1 - 1.6e-108 363.2 0.0 1.8e-108 363.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.22 GAP93130.1 - 1.3e-21 76.6 1.8 5.7e-21 74.5 0.3 2.6 3 0 0 3 3 3 1 Ribosomal protein S15 Ribosomal_S2 PF00318.20 GAP93131.1 - 7.9e-26 90.6 0.2 3.1e-14 52.7 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 GAP93131.1 - 0.035 15.4 15.8 0.19 13.1 15.8 2.2 1 1 0 1 1 1 0 40S ribosomal protein SA C-terminus p450 PF00067.22 GAP93132.1 - 1.1e-25 90.3 0.0 1.7e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 RasGEF PF00617.19 GAP93133.1 - 5.5e-47 160.2 0.2 9.1e-47 159.5 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 GAP93133.1 - 1.2e-15 57.6 0.4 3.1e-15 56.3 0.4 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Peptidase_M36 PF02128.15 GAP93134.1 - 1.1e-145 485.5 1.0 1.4e-145 485.2 1.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 GAP93134.1 - 4.8e-16 58.3 3.6 1.1e-15 57.2 3.6 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif DUF4901 PF16244.5 GAP93134.1 - 0.08 12.3 0.1 0.19 11.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4901) ADH_N PF08240.12 GAP93135.1 - 2.6e-20 72.3 1.3 6.3e-20 71.1 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 GAP93135.1 - 2.6e-19 69.5 2.4 2.6e-19 69.5 2.4 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 GAP93135.1 - 6.1e-06 27.3 1.2 1.1e-05 26.5 1.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase BTB_2 PF02214.22 GAP93136.1 - 6.1e-08 32.9 0.0 0.00025 21.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain HET PF06985.11 GAP93137.1 - 2.8e-24 86.1 0.0 5.1e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PhyH PF05721.13 GAP93138.1 - 1.5e-09 38.4 0.1 2.1e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SelB-wing_2 PF09106.11 GAP93138.1 - 0.13 12.5 0.0 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor SelB, winged helix PAP2 PF01569.21 GAP93139.1 - 3.8e-21 75.3 1.8 1.2e-20 73.7 1.8 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 GAP93139.1 - 0.00081 19.1 3.7 0.00081 19.1 3.7 2.2 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 GAP93139.1 - 0.67 10.1 2.6 0.92 9.6 0.1 2.2 1 1 1 2 2 2 0 Divergent PAP2 family CHD5 PF04420.14 GAP93139.1 - 1.7 8.5 3.4 0.74 9.7 0.4 2.0 2 0 0 2 2 2 0 CHD5-like protein adh_short PF00106.25 GAP93140.1 - 7.9e-24 84.2 0.0 9.4e-22 77.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 GAP93140.1 - 9.9e-16 58.0 0.0 1.4e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP93140.1 - 6e-07 29.5 0.0 8.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 KR domain TIR-like PF10137.9 GAP93140.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain GDP_Man_Dehyd PF16363.5 GAP93140.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 GAP93140.1 - 0.048 13.1 0.0 0.077 12.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 GAP93140.1 - 0.19 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_4 PF01565.23 GAP93141.1 - 9.7e-20 70.7 1.5 9.7e-20 70.7 1.5 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 GAP93141.1 - 3e-10 40.0 0.9 8e-10 38.7 0.9 1.7 1 0 0 1 1 1 1 Berberine and berberine like TPR_12 PF13424.6 GAP93142.1 - 1.6e-95 313.5 27.1 7e-20 71.1 0.6 6.6 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 GAP93142.1 - 4.2e-73 239.5 8.6 1.2e-10 40.8 0.4 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 GAP93142.1 - 3.7e-38 127.8 21.7 3.1e-06 26.8 0.2 8.4 8 1 0 8 8 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 GAP93142.1 - 4.7e-25 85.7 6.4 0.00067 19.5 0.1 8.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 GAP93142.1 - 5.2e-24 82.4 21.1 0.00049 20.1 0.2 8.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_MalT PF17874.1 GAP93142.1 - 1.2e-22 80.7 1.9 5.5e-09 35.9 0.0 3.2 1 1 2 3 3 3 3 MalT-like TPR region TPR_2 PF07719.17 GAP93142.1 - 1.1e-21 75.1 23.0 0.0011 18.9 0.2 8.7 8 2 0 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 GAP93142.1 - 7.1e-18 63.8 2.9 0.51 11.3 0.1 8.4 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 GAP93142.1 - 1.5e-17 62.6 2.8 0.68 10.4 0.0 8.3 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAP93142.1 - 1.1e-16 61.2 3.0 0.0012 19.5 0.1 6.0 3 2 1 4 4 4 4 Tetratricopeptide repeat HET PF06985.11 GAP93142.1 - 1.6e-11 44.8 1.3 5.6e-08 33.2 0.1 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 GAP93142.1 - 4.3e-11 42.5 0.0 8.5e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 GAP93142.1 - 1.5e-08 35.0 8.1 0.081 13.4 0.4 5.1 3 1 1 4 4 4 3 Tetratricopeptide repeat 14-3-3 PF00244.20 GAP93142.1 - 4.2e-08 33.0 4.7 0.0075 15.8 0.0 4.9 1 1 4 5 5 5 2 14-3-3 protein DUF2225 PF09986.9 GAP93142.1 - 5.4e-08 32.8 2.6 0.15 11.8 0.0 3.5 1 1 2 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 GAP93142.1 - 1.1e-06 28.7 0.0 14 6.7 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5344 PF17279.2 GAP93142.1 - 3.7e-06 27.4 3.2 3.2 8.4 0.0 6.6 4 2 2 6 6 6 1 Family of unknown function (DUF5344) ATPase_2 PF01637.18 GAP93142.1 - 8.7e-06 25.8 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 GAP93142.1 - 1e-05 26.0 1.9 3.5e-05 24.3 1.9 2.1 1 1 0 1 1 1 1 AAA ATPase domain SNAP PF14938.6 GAP93142.1 - 1.2e-05 24.9 0.0 0.0038 16.7 0.0 2.4 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP PPR PF01535.20 GAP93142.1 - 0.00022 21.2 4.3 29 5.2 0.0 6.0 6 0 0 6 6 6 0 PPR repeat TPR_21 PF09976.9 GAP93142.1 - 0.00047 19.9 8.8 5.7 6.6 0.1 5.4 2 2 4 6 6 6 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 GAP93142.1 - 0.0021 18.6 18.2 5.3 7.9 0.1 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 GAP93142.1 - 0.0068 16.2 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RPN7 PF10602.9 GAP93142.1 - 0.0089 15.8 1.5 15 5.2 0.0 4.2 2 1 2 4 4 4 0 26S proteasome subunit RPN7 DUF2989 PF11207.8 GAP93142.1 - 0.012 15.4 3.9 0.32 10.7 0.1 3.8 2 1 3 5 5 5 0 Protein of unknown function (DUF2989) TPR_11 PF13414.6 GAP93142.1 - 0.035 13.8 29.0 0.35 10.6 0.2 7.6 8 1 0 8 8 8 0 TPR repeat AAA_22 PF13401.6 GAP93142.1 - 0.039 14.2 0.0 0.25 11.6 0.0 2.3 1 1 1 2 2 2 0 AAA domain Spatacsin_C PF14649.6 GAP93142.1 - 0.056 12.6 0.3 0.19 10.8 0.1 1.8 1 1 1 2 2 2 0 Spatacsin C-terminus Wzy_C_2 PF11846.8 GAP93142.1 - 0.094 12.6 1.4 11 5.9 0.1 3.6 3 2 1 4 4 3 0 Virulence factor membrane-bound polymerase, C-terminal Phage_T4_Ndd PF06591.11 GAP93142.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) AAA_14 PF13173.6 GAP93142.1 - 0.13 12.3 0.0 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain RPN6_N PF18055.1 GAP93142.1 - 0.41 11.0 4.3 18 5.7 0.3 3.8 2 1 3 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain Mad3_BUB1_I PF08311.12 GAP93142.1 - 0.5 10.4 2.4 85 3.2 0.0 4.2 5 0 0 5 5 4 0 Mad3/BUB1 homology region 1 Ank_2 PF12796.7 GAP93143.1 - 3.2e-91 300.0 0.2 1.7e-08 34.9 0.0 17.0 9 4 8 18 18 18 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP93143.1 - 2.1e-78 257.8 31.5 2e-06 28.2 0.0 29.0 20 9 10 30 30 30 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP93143.1 - 4e-57 183.4 17.1 0.00054 20.2 0.0 28.2 31 1 1 32 32 31 8 Ankyrin repeat Ank PF00023.30 GAP93143.1 - 1.1e-55 183.7 48.0 0.00018 21.8 0.0 26.5 29 1 1 30 30 30 12 Ankyrin repeat Ank_5 PF13857.6 GAP93143.1 - 4e-54 180.0 39.3 0.0001 22.5 0.0 23.0 19 7 6 25 25 25 17 Ankyrin repeats (many copies) NACHT PF05729.12 GAP93143.1 - 4.8e-09 36.3 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 GAP93143.1 - 7.7e-05 23.1 0.0 0.00048 20.6 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 GAP93143.1 - 0.031 14.8 0.0 3.4 8.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 GAP93143.1 - 0.036 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Slx4 PF09494.10 GAP93143.1 - 0.13 12.2 0.3 2.4 8.2 0.0 2.9 3 0 0 3 3 3 0 Slx4 endonuclease NB-ARC PF00931.22 GAP93143.1 - 0.23 10.6 0.0 0.48 9.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNase_H PF00075.24 GAP93144.1 - 6.1e-25 88.1 0.0 1e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 GAP93144.1 - 1.7e-05 24.6 0.4 0.00066 19.5 0.4 2.4 1 1 0 1 1 1 1 Reverse transcriptase-like Glyco_hydro_61 PF03443.14 GAP93146.1 - 1.4e-33 116.6 0.0 2.2e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ANAPC8 PF04049.13 GAP93147.1 - 1.4e-53 180.7 0.0 3.3e-53 179.5 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 GAP93147.1 - 5.3e-19 66.8 10.7 6.7e-05 22.8 0.0 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 GAP93147.1 - 2e-17 62.2 7.7 0.00063 19.5 0.0 6.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 GAP93147.1 - 7.7e-11 41.2 20.4 0.27 11.4 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 GAP93147.1 - 1.4e-10 41.1 12.9 0.0055 17.4 0.1 6.9 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 GAP93147.1 - 3.9e-10 40.2 6.6 5.3e-06 27.0 0.7 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 GAP93147.1 - 8.4e-08 31.8 0.3 2.3e-06 27.2 0.1 2.9 2 0 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 GAP93147.1 - 4.3e-07 30.1 7.6 0.18 12.0 0.6 5.8 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 GAP93147.1 - 2.2e-06 27.8 16.6 0.26 11.6 0.0 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 GAP93147.1 - 4.1e-05 23.3 10.6 0.12 12.4 0.1 5.8 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 GAP93147.1 - 8.9e-05 22.9 13.1 1.2 9.7 0.0 6.3 6 1 2 8 8 7 3 Tetratricopeptide repeat DUF3856 PF12968.7 GAP93147.1 - 0.00024 21.2 1.4 0.012 15.7 0.2 2.9 1 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) ChAPs PF09295.10 GAP93147.1 - 0.0097 14.9 0.0 2.2 7.2 0.0 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.6 GAP93147.1 - 0.02 15.2 0.3 9.1 6.9 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Say1_Mug180 PF10340.9 GAP93147.1 - 0.049 12.5 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPR_9 PF13371.6 GAP93147.1 - 0.093 12.9 15.9 0.15 12.2 0.1 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.12 GAP93147.1 - 0.16 12.7 9.7 12 6.8 0.2 4.8 4 0 0 4 4 4 0 Sel1 repeat TPR_10 PF13374.6 GAP93147.1 - 0.18 11.7 5.8 15 5.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat polyprenyl_synt PF00348.17 GAP93148.1 - 5.1e-91 304.3 0.0 6.3e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.22 GAP93149.1 - 4.9e-31 108.0 0.0 1.2e-24 86.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 PH PF00169.29 GAP93150.1 - 4.2e-05 24.0 1.0 0.00011 22.6 0.7 1.8 1 1 0 1 1 1 1 PH domain BatD PF13584.6 GAP93151.1 - 0.0051 15.7 0.2 0.024 13.4 0.1 1.8 1 1 1 2 2 2 2 Oxygen tolerance DUF2207 PF09972.9 GAP93151.1 - 0.011 14.6 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MGC-24 PF05283.11 GAP93151.1 - 0.029 14.8 4.8 0.029 14.8 4.8 2.4 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4690 PF15756.5 GAP93151.1 - 0.043 14.4 0.5 0.043 14.4 0.5 2.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage FeoB_associated PF12669.7 GAP93151.1 - 0.097 13.1 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4381 PF14316.6 GAP93151.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMEM154 PF15102.6 GAP93151.1 - 0.17 11.8 0.1 0.17 11.8 0.1 1.9 2 1 0 2 2 2 0 TMEM154 protein family Podoplanin PF05808.11 GAP93151.1 - 0.19 11.9 12.1 0.44 10.7 12.1 1.6 1 1 0 1 1 1 0 Podoplanin LapA_dom PF06305.11 GAP93151.1 - 0.23 11.3 0.7 0.43 10.4 0.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Amnionless PF14828.6 GAP93151.1 - 0.4 9.5 2.2 0.67 8.7 0.2 1.9 2 0 0 2 2 2 0 Amnionless MSP1_C PF07462.11 GAP93151.1 - 0.54 8.9 2.5 0.67 8.6 2.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RmlD_sub_bind PF04321.17 GAP93152.1 - 2.5e-53 181.0 0.0 3e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 GAP93152.1 - 6.7e-21 74.8 0.0 1.2e-20 74.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP93152.1 - 4.6e-10 39.4 0.0 1.9e-09 37.4 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 GAP93152.1 - 2.3e-07 30.2 0.7 3.8e-05 23.0 0.1 3.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 GAP93152.1 - 5.2e-07 29.1 0.0 0.00016 20.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 GAP93152.1 - 1.1e-06 27.9 0.0 3e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 GAP93152.1 - 0.062 12.9 0.0 0.78 9.2 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family B-block_TFIIIC PF04182.12 GAP93155.1 - 5.8e-13 48.8 0.0 1.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC zf-3CxxC_2 PF17180.4 GAP93155.1 - 0.075 13.8 0.4 0.19 12.5 0.4 1.7 1 0 0 1 1 1 0 Zinc-binding domain Amino_oxidase PF01593.24 GAP93156.1 - 2.8e-47 162.0 0.8 8.3e-47 160.5 0.8 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 GAP93156.1 - 1.6e-12 47.5 0.3 4.3e-12 46.1 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 GAP93156.1 - 3e-06 27.1 0.0 8.6e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP93156.1 - 9.2e-05 21.7 0.1 0.00025 20.3 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 GAP93156.1 - 0.00017 21.0 0.5 0.00041 19.7 0.1 1.9 2 1 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 GAP93156.1 - 0.0002 20.7 0.1 0.00034 20.0 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 GAP93156.1 - 0.0031 16.9 0.0 0.0064 15.9 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 GAP93156.1 - 0.0036 16.1 0.1 0.0075 15.0 0.1 1.6 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 GAP93156.1 - 0.0074 15.5 0.0 0.08 12.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 GAP93156.1 - 0.019 15.5 0.3 0.049 14.2 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 GAP93156.1 - 0.025 13.8 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 GAP93156.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HNH_2 PF13391.6 GAP93158.1 - 2.4e-15 56.4 0.1 1e-14 54.4 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease p450 PF00067.22 GAP93160.1 - 4.7e-45 154.2 0.0 5.8e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Monellin PF09200.10 GAP93160.1 - 0.12 12.3 0.4 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Monellin MFS_1 PF07690.16 GAP93162.1 - 3.1e-38 131.6 43.8 1.5e-37 129.4 43.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP93162.1 - 2e-14 53.3 12.2 2e-14 53.3 12.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter ketoacyl-synt PF00109.26 GAP93163.1 - 8.8e-63 212.2 0.0 1.7e-62 211.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 GAP93163.1 - 3.3e-56 190.0 0.6 6.3e-56 189.1 0.6 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 GAP93163.1 - 6.9e-47 160.5 0.9 1.8e-46 159.1 0.0 2.1 3 0 0 3 3 3 1 Acyl transferase domain PS-DH PF14765.6 GAP93163.1 - 1.3e-42 146.1 1.4 3.9e-42 144.5 0.3 2.2 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 GAP93163.1 - 7e-38 129.3 0.0 2e-37 127.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 GAP93163.1 - 7.1e-19 69.2 0.0 2.2e-17 64.4 0.0 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 GAP93163.1 - 8e-18 65.0 0.0 2.8e-17 63.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 GAP93163.1 - 1.2e-13 51.0 0.0 2.8e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 GAP93163.1 - 1.9e-13 50.5 1.3 2e-12 47.2 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 GAP93163.1 - 7.4e-13 48.9 0.0 7.2e-12 45.8 0.0 2.6 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 GAP93163.1 - 8.2e-12 45.3 0.0 1.9e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP93163.1 - 1.7e-11 44.6 0.0 6.6e-11 42.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP93163.1 - 2.5e-11 44.1 0.0 1.3e-09 38.6 0.0 3.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP93163.1 - 2.9e-11 43.4 0.0 6.7e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 GAP93163.1 - 1.8e-09 37.5 0.0 3.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 GAP93163.1 - 1.6e-08 34.7 0.0 7.4e-08 32.6 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 GAP93163.1 - 8.1e-06 25.7 0.6 2.4e-05 24.2 0.6 1.8 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 GAP93163.1 - 0.00016 21.4 0.2 0.00044 20.0 0.2 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sacchrp_dh_NADP PF03435.18 GAP93163.1 - 0.00038 20.7 0.1 0.0028 17.9 0.0 2.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Ubie_methyltran PF01209.18 GAP93163.1 - 0.00098 18.5 0.0 0.0087 15.4 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 GAP93163.1 - 0.0078 15.9 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Epimerase PF01370.21 GAP93163.1 - 0.032 13.7 0.0 0.074 12.5 0.0 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 GAP93163.1 - 0.033 14.1 0.1 0.074 12.9 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 GAP93163.1 - 0.092 12.1 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain tRNA-synt_1b PF00579.25 GAP93165.1 - 6e-32 111.1 0.0 6.9e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) adh_short_C2 PF13561.6 GAP93166.1 - 1e-36 126.7 5.7 2.5e-21 76.3 0.0 3.0 3 0 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 GAP93166.1 - 1.3e-32 112.9 8.3 1.6e-19 70.1 3.2 2.9 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAP93166.1 - 2.8e-10 40.4 2.3 2.8e-10 40.4 2.3 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 GAP93166.1 - 0.0068 15.6 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Dak1_2 PF13684.6 GAP93166.1 - 0.063 12.4 0.1 0.085 11.9 0.1 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Thymidylate_kin PF02223.17 GAP93167.1 - 5.7e-42 143.5 0.1 1.1e-40 139.3 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 GAP93167.1 - 0.0018 18.5 0.0 0.0038 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Pkinase PF00069.25 GAP93170.1 - 1e-32 113.6 0.0 1.4e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP93170.1 - 6.7e-12 45.2 0.0 1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 GAP93170.1 - 2.6e-05 24.3 0.0 4.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 GAP93170.1 - 0.00071 19.0 0.0 0.0018 17.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 GAP93170.1 - 0.035 13.7 0.1 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 GAP93170.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 GAP93170.1 - 0.11 11.2 0.1 0.2 10.4 0.1 1.5 1 1 0 1 1 1 0 Fungal protein kinase Lambda_Kil PF06301.11 GAP93170.1 - 0.16 11.6 0.6 0.44 10.2 0.6 1.7 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein DUF2497 PF10691.9 GAP93171.1 - 0.1 13.1 1.0 3.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) NACHT PF05729.12 GAP93172.1 - 2.7e-08 33.9 0.1 2.5e-06 27.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 GAP93172.1 - 2.6e-05 24.7 0.2 0.00014 22.2 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 GAP93172.1 - 0.0016 18.9 0.0 0.0082 16.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter Helo_like_N PF17111.5 GAP93172.1 - 0.0047 16.3 0.7 0.013 14.8 0.2 2.0 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_23 PF13476.6 GAP93172.1 - 0.014 15.9 2.5 2.4 8.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 GAP93172.1 - 0.03 13.5 0.0 0.073 12.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 GAP93172.1 - 0.032 14.2 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 GAP93172.1 - 0.035 13.8 0.1 0.078 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 GAP93172.1 - 0.051 13.9 0.0 0.22 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 GAP93172.1 - 0.054 13.4 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 GAP93172.1 - 0.062 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 GAP93172.1 - 0.3 11.6 2.7 2.5 8.6 0.0 3.1 3 0 0 3 3 3 0 Cell division protein ZapB Terpene_synth_C PF03936.16 GAP93173.1 - 4.7e-06 26.2 1.5 6.7e-06 25.7 1.5 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 GAP93173.1 - 0.022 13.6 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) CENP-P PF13096.6 GAP93173.1 - 0.087 12.5 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Methyltransf_23 PF13489.6 GAP93175.1 - 1.1e-16 61.1 0.0 1.8e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP93175.1 - 8.3e-10 39.3 0.0 1.9e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP93175.1 - 2.9e-07 31.0 0.0 5.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP93175.1 - 3.2e-07 31.0 0.0 6.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP93175.1 - 2.7e-05 24.0 0.0 0.00012 21.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 GAP93175.1 - 4e-05 23.0 0.0 0.00024 20.5 0.0 2.0 1 1 1 2 2 2 1 O-methyltransferase domain MTS PF05175.14 GAP93175.1 - 0.00068 19.2 0.0 0.0028 17.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 GAP93175.1 - 0.00097 18.6 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 GAP93175.1 - 0.0056 16.0 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 GAP93175.1 - 0.009 16.1 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 GAP93175.1 - 0.014 15.2 0.0 0.029 14.1 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase DUF938 PF06080.12 GAP93175.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) p450 PF00067.22 GAP93176.1 - 6.6e-47 160.3 0.0 9.2e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 GAP93177.1 - 4e-11 43.9 0.0 5.2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family GMC_oxred_N PF00732.19 GAP93178.1 - 4.8e-48 164.0 0.0 6.3e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP93178.1 - 7.3e-32 110.9 0.0 1.2e-31 110.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 GAP93178.1 - 9.1e-08 32.1 0.1 7e-07 29.2 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 GAP93178.1 - 1.5e-05 24.3 0.2 7.7e-05 22.1 0.2 1.9 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 GAP93178.1 - 3.1e-05 23.2 0.2 4.7e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 GAP93178.1 - 4e-05 22.9 0.2 0.0024 17.0 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 GAP93178.1 - 0.00018 21.6 0.2 0.00047 20.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP93178.1 - 0.00041 19.7 0.1 0.00075 18.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAP93178.1 - 0.014 14.3 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 GAP93178.1 - 0.022 14.0 0.0 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 GAP93178.1 - 0.058 13.4 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 GAP93178.1 - 0.12 11.0 0.4 0.17 10.5 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.25 GAP93179.1 - 2.7e-09 36.8 0.0 1.6e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAP93179.1 - 0.0002 21.3 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 GAP93179.1 - 0.00069 19.5 0.3 0.01 15.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 GAP93179.1 - 0.0018 17.5 0.0 0.0039 16.4 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 GAP93179.1 - 0.0043 16.5 0.0 0.025 14.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1490 PF07371.12 GAP93179.1 - 0.12 12.4 1.9 0.27 11.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1490) Cupin_2 PF07883.11 GAP93180.1 - 1.3e-07 31.2 0.5 3.6e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 Cupin domain FAD_binding_4 PF01565.23 GAP93181.1 - 5.7e-27 94.1 0.3 1.1e-26 93.2 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Ribosomal_L44 PF00935.19 GAP93181.1 - 0.51 10.9 3.7 0.92 10.0 3.7 1.3 1 0 0 1 1 1 0 Ribosomal protein L44 UbiA PF01040.18 GAP93182.1 - 2.6e-41 141.6 19.8 2.6e-41 141.6 19.8 2.0 1 1 1 2 2 2 2 UbiA prenyltransferase family adh_short PF00106.25 GAP93183.1 - 1.6e-47 161.5 1.8 2.1e-47 161.1 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP93183.1 - 4.2e-41 141.0 1.4 5.2e-41 140.7 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP93183.1 - 6.2e-12 45.8 0.3 9.2e-12 45.2 0.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 GAP93183.1 - 0.00013 21.9 0.1 0.00023 21.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 GAP93183.1 - 0.00029 20.4 0.3 0.00042 19.9 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 GAP93183.1 - 0.00051 19.5 0.0 0.00074 19.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 GAP93183.1 - 0.0045 16.3 0.5 0.007 15.7 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PglD_N PF17836.1 GAP93183.1 - 0.011 16.4 0.1 0.02 15.5 0.1 1.4 1 0 0 1 1 1 0 PglD N-terminal domain 3Beta_HSD PF01073.19 GAP93183.1 - 0.015 14.3 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Kelch_4 PF13418.6 GAP93183.1 - 0.035 14.1 0.3 0.096 12.7 0.3 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain TrkA_N PF02254.18 GAP93183.1 - 0.073 13.3 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 GAP93183.1 - 0.079 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 GAP93183.1 - 0.081 12.5 0.4 0.16 11.5 0.4 1.5 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 GAP93183.1 - 0.085 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_hydro_79C PF16862.5 GAP93184.1 - 1.8e-17 64.1 1.8 4.6e-17 62.8 1.8 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Lipase_GDSL_2 PF13472.6 GAP93185.1 - 4.7e-12 46.7 0.3 6.5e-12 46.2 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP93185.1 - 2.2e-06 27.8 0.0 3.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PRIMA1 PF16101.5 GAP93185.1 - 1.9 8.5 11.6 4.2 7.4 11.6 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 GAP93185.1 - 4.6 7.2 6.0 7.2 6.6 6.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Metallophos PF00149.28 GAP93186.1 - 1.3e-08 35.6 3.5 1.9e-08 35.0 2.9 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SET PF00856.28 GAP93187.1 - 1.2e-12 48.5 0.0 4.7e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 SET domain DUF295 PF03478.18 GAP93187.1 - 0.31 10.7 1.3 0.43 10.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF295) GTP_cyclohydroI PF01227.22 GAP93188.1 - 7.6e-75 250.3 0.5 1.1e-74 249.8 0.5 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 GAP93188.1 - 0.00033 20.7 0.1 0.0008 19.5 0.0 1.6 2 0 0 2 2 2 1 QueF-like protein DUF3638 PF12340.8 GAP93188.1 - 0.084 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) SRP-alpha_N PF04086.13 GAP93188.1 - 1.9 8.4 12.0 2.7 7.8 12.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TAFII28 PF04719.14 GAP93189.1 - 2.2e-28 98.2 0.0 4.5e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Caps_synth PF05704.12 GAP93190.1 - 1.9e-10 40.6 0.0 3.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 GAP93190.1 - 0.0001 22.8 0.0 0.0002 21.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Dioxygenase_C PF00775.21 GAP93192.1 - 3e-08 33.3 0.0 4.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Methyltransf_31 PF13847.6 GAP93193.1 - 1.1e-24 87.0 0.0 1.9e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP93193.1 - 3.9e-24 85.2 0.1 1.1e-23 83.8 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP93193.1 - 3.4e-23 82.1 0.1 8.2e-23 80.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP93193.1 - 5.7e-16 59.1 0.0 1.1e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP93193.1 - 8.2e-14 51.8 0.0 2.5e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP93193.1 - 2.1e-10 40.3 0.0 3.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 GAP93193.1 - 4.8e-08 32.8 0.0 1.2e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 GAP93193.1 - 5e-08 32.7 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 GAP93193.1 - 1.9e-06 27.0 0.0 2.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 GAP93193.1 - 1.2e-05 24.9 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 GAP93193.1 - 2.2e-05 24.3 0.0 3.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 GAP93193.1 - 6.4e-05 23.0 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 GAP93193.1 - 9.1e-05 22.0 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain CMAS PF02353.20 GAP93193.1 - 0.0027 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltr_RsmB-F PF01189.17 GAP93193.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 GAP93193.1 - 0.025 14.7 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 GAP93193.1 - 0.028 14.4 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 GAP93193.1 - 0.037 13.6 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Nodulation protein S (NodS) DREV PF05219.12 GAP93193.1 - 0.046 12.8 0.0 0.59 9.2 0.0 2.0 1 1 0 1 1 1 0 DREV methyltransferase DUF938 PF06080.12 GAP93193.1 - 0.052 13.3 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 GAP93193.1 - 0.1 12.0 0.1 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_hydro_16 PF00722.21 GAP93194.1 - 0.00011 21.7 0.5 0.0007 19.1 0.0 2.3 3 1 0 3 3 3 1 Glycosyl hydrolases family 16 SUIM_assoc PF16619.5 GAP93194.1 - 0.19 11.8 11.0 0.38 10.9 11.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 GAP93194.1 - 9.4 6.1 11.6 12 5.8 11.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Arm PF00514.23 GAP93195.1 - 3.1e-72 236.6 30.1 2.4e-11 43.3 0.2 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 GAP93195.1 - 6.3e-16 58.5 9.8 0.00025 21.4 0.1 6.8 5 2 0 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 GAP93195.1 - 1.2e-15 57.7 13.5 4.9e-05 23.7 0.4 7.2 5 2 2 7 7 7 3 HEAT-like repeat HEAT PF02985.22 GAP93195.1 - 3.4e-14 51.7 15.2 0.05 13.9 0.3 8.6 10 0 0 10 10 8 5 HEAT repeat Arm_2 PF04826.13 GAP93195.1 - 2.4e-10 40.3 5.0 1.3e-06 28.1 1.9 2.6 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 GAP93195.1 - 3e-08 33.4 1.9 0.00041 19.7 0.3 3.4 2 1 1 3 3 3 2 V-ATPase subunit H Adaptin_N PF01602.20 GAP93195.1 - 5.3e-08 31.9 9.3 1.2e-07 30.7 5.5 2.8 2 1 0 2 2 2 1 Adaptin N terminal region KAP PF05804.12 GAP93195.1 - 1.5e-07 30.0 0.8 2.6e-07 29.2 0.8 1.5 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Cnd1 PF12717.7 GAP93195.1 - 4.5e-05 23.5 4.5 0.019 15.0 0.1 4.6 1 1 4 6 6 6 1 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 GAP93195.1 - 0.0004 20.3 6.8 0.74 9.7 0.1 3.9 2 1 2 4 4 4 2 Domain of unknown function (DUF3361) DUF5578 PF17741.1 GAP93195.1 - 0.0019 17.7 6.2 2.7 7.3 0.2 4.9 2 2 3 5 5 5 2 Family of unknown function (DUF5578) Atx10homo_assoc PF09759.9 GAP93195.1 - 0.0033 17.4 3.2 8 6.6 0.2 4.3 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 GAP93195.1 - 0.0073 16.9 5.9 21 6.1 0.1 6.7 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 GAP93195.1 - 0.053 13.5 1.2 3.6 7.5 0.1 3.3 2 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Vpu PF00558.19 GAP93195.1 - 0.061 13.1 0.9 0.17 11.7 0.3 2.0 2 0 0 2 2 2 0 Vpu protein Peptidase_S26 PF10502.9 GAP93196.1 - 3.9e-07 29.9 0.0 5.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 GAP93196.1 - 6.7e-06 26.0 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like mIF3 PF14877.6 GAP93198.1 - 0.00055 19.6 0.0 0.00055 19.6 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial translation initiation factor IF3_C PF00707.22 GAP93198.1 - 0.00066 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain TraK PF06586.11 GAP93198.1 - 0.024 14.4 0.1 0.024 14.4 0.1 1.5 2 0 0 2 2 2 0 TraK protein DUF3499 PF12005.8 GAP93198.1 - 0.047 14.3 1.3 0.098 13.3 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3499) Transglut_core3 PF13471.6 GAP93198.1 - 0.078 12.9 0.3 0.078 12.9 0.3 2.5 3 0 0 3 3 3 0 Transglutaminase-like superfamily Glyco_hydro_76 PF03663.14 GAP93199.1 - 7.2e-144 479.8 13.0 2.3e-141 471.5 13.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 GAP93199.1 - 1.7e-05 24.1 7.5 0.013 14.6 0.5 3.1 2 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 NAP PF00956.18 GAP93200.1 - 8.4e-28 97.3 9.8 8.1e-26 90.8 4.5 2.4 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) BUD22 PF09073.10 GAP93200.1 - 0.0019 17.6 16.1 0.0027 17.1 16.1 1.1 1 0 0 1 1 1 1 BUD22 Cwf_Cwc_15 PF04889.12 GAP93200.1 - 0.0036 17.1 10.0 0.0036 17.1 10.0 2.2 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Adeno_terminal PF02459.15 GAP93200.1 - 0.49 8.7 2.4 0.87 7.9 2.4 1.4 1 0 0 1 1 1 0 Adenoviral DNA terminal protein CENP-B_dimeris PF09026.10 GAP93200.1 - 3.9 7.9 27.2 4.8 7.6 11.9 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Voldacs PF03517.13 GAP93200.1 - 6.6 6.9 16.7 16 5.6 16.7 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Tim17 PF02466.19 GAP93201.1 - 7.4e-39 132.6 8.8 8.8e-39 132.3 8.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_16 PF00722.21 GAP93202.1 - 7.6e-11 41.8 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 LPAM_2 PF13627.6 GAP93202.1 - 0.22 11.4 0.2 0.61 10.0 0.2 1.8 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site SCO1-SenC PF02630.14 GAP93203.1 - 3.7e-50 169.3 0.0 5e-50 168.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 GAP93203.1 - 2.3e-06 27.5 0.0 4.1e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAP93203.1 - 0.012 15.4 0.0 0.25 11.0 0.0 2.2 1 1 0 1 1 1 0 Redoxin DUF3343 PF11823.8 GAP93203.1 - 0.033 13.6 0.0 0.08 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Thioredoxin_8 PF13905.6 GAP93203.1 - 0.044 14.1 0.0 0.078 13.3 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Hydrolase_6 PF13344.6 GAP93204.1 - 6.7e-23 80.7 0.0 1.2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 GAP93204.1 - 3.5e-17 62.2 0.1 2.2e-16 59.7 0.0 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 GAP93204.1 - 0.00037 20.9 0.1 5.3 7.3 0.0 4.1 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 GAP93204.1 - 0.0048 17.0 0.0 0.87 9.6 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Choline_kinase PF01633.20 GAP93205.1 - 1.4e-61 207.8 0.0 2.8e-61 206.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 GAP93205.1 - 5.1e-20 70.9 0.0 1e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 GAP93205.1 - 3.2e-06 27.2 0.3 0.00019 21.5 0.0 3.3 3 1 0 3 3 3 1 Phosphotransferase enzyme family zf-C2H2 PF00096.26 GAP93208.1 - 7.1e-09 35.7 12.2 0.00045 20.5 2.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 GAP93208.1 - 8.7e-06 25.9 10.2 3.2e-05 24.1 2.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 GAP93208.1 - 8.6e-05 23.1 11.4 0.088 13.7 2.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 GAP93208.1 - 0.0099 15.9 0.9 0.0099 15.9 0.9 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger Rpr2 PF04032.16 GAP93208.1 - 0.011 16.0 0.2 0.072 13.4 0.0 2.2 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_jaz PF12171.8 GAP93208.1 - 0.047 14.0 4.5 0.074 13.4 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CCAP PF11105.8 GAP93208.1 - 0.058 13.4 0.8 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a zf-met PF12874.7 GAP93208.1 - 0.069 13.6 1.6 0.069 13.6 1.6 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 GAP93208.1 - 0.25 11.5 2.2 2 8.6 0.8 2.3 1 1 1 2 2 2 0 Zinc ribbon domain Lipase_GDSL_2 PF13472.6 GAP93209.1 - 4.6e-11 43.4 2.2 5.9e-11 43.1 0.7 2.0 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 GAP93209.1 - 1.3e-09 38.3 1.3 3.5e-09 36.9 1.3 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF327 PF03885.13 GAP93210.1 - 0.0018 18.2 1.2 1.6 8.7 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF327) Use1 PF09753.9 GAP93210.1 - 0.0072 16.1 0.1 0.043 13.5 0.0 2.0 2 0 0 2 2 2 1 Membrane fusion protein Use1 BORCS6 PF10157.9 GAP93210.1 - 0.011 16.0 0.5 0.014 15.6 0.5 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DUF2633 PF11119.8 GAP93210.1 - 0.025 14.5 1.8 0.051 13.5 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) BAR_2 PF10455.9 GAP93210.1 - 0.077 12.1 1.0 0.099 11.8 1.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking CMD PF02627.20 GAP93210.1 - 0.081 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family UreE_C PF05194.12 GAP93210.1 - 0.086 13.3 11.8 0.058 13.9 9.9 1.8 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain YscO PF07321.12 GAP93210.1 - 0.2 11.6 5.6 0.074 13.0 1.0 2.1 1 1 0 2 2 2 0 Type III secretion protein YscO Not3 PF04065.15 GAP93210.1 - 0.25 10.8 5.3 0.3 10.5 0.2 2.0 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component HSBP1 PF06825.12 GAP93210.1 - 2.7 7.9 6.5 12 5.9 0.3 2.9 3 0 0 3 3 3 0 Heat shock factor binding protein 1 PHD PF00628.29 GAP93211.1 - 2.6e-08 33.6 2.1 2.6e-08 33.6 2.1 2.2 2 0 0 2 2 2 1 PHD-finger PHD_4 PF16866.5 GAP93211.1 - 0.16 12.1 2.8 0.3 11.2 2.8 1.5 1 0 0 1 1 1 0 PHD-finger Carla_C4 PF01623.17 GAP93211.1 - 1.6 8.7 5.4 1.9 8.5 1.9 2.2 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein NACHT_N PF17100.5 GAP93212.1 - 0.028 14.3 0.1 0.082 12.8 0.1 1.9 1 1 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase DUF2680 PF10925.8 GAP93212.1 - 0.87 9.6 7.0 0.97 9.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Med9 PF07544.13 GAP93212.1 - 1 9.5 7.3 0.74 9.9 0.2 3.2 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.15 GAP93212.1 - 4.7 7.1 12.6 2.3 8.1 2.9 3.4 4 0 0 4 4 4 0 Septum formation initiator AAA PF00004.29 GAP93213.1 - 5e-17 62.6 0.0 1.1e-16 61.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP93213.1 - 0.00042 20.7 0.1 0.0011 19.3 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 GAP93213.1 - 0.0021 17.8 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 GAP93213.1 - 0.0071 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 GAP93213.1 - 0.0072 16.9 1.4 0.16 12.5 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 GAP93213.1 - 0.013 15.8 0.1 0.14 12.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 GAP93213.1 - 0.038 13.6 0.1 0.085 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAP93213.1 - 0.04 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 GAP93213.1 - 0.042 14.3 0.6 0.14 12.6 0.0 2.3 3 0 0 3 3 3 0 RNA helicase RuvB_N PF05496.12 GAP93213.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NAT PF04768.13 GAP93214.1 - 0.044 13.4 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase FA_desaturase PF00487.24 GAP93215.1 - 7.2e-09 35.9 30.5 7.2e-09 35.9 30.5 2.0 1 1 1 2 2 2 1 Fatty acid desaturase SF1-HH PF16275.5 GAP93216.1 - 2.6e-44 150.2 7.3 4.3e-44 149.5 1.0 2.5 1 1 1 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 GAP93216.1 - 7e-12 44.9 11.1 1.3e-05 25.0 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 GAP93216.1 - 2.7e-08 33.5 0.1 5.1e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 GAP93216.1 - 1.6e-06 28.0 6.7 0.0022 17.9 3.4 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 GAP93216.1 - 0.00039 20.2 8.1 0.085 12.7 0.6 2.8 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 GAP93216.1 - 0.0014 18.3 5.0 0.44 10.3 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 GAP93216.1 - 0.015 15.2 0.5 0.015 15.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 GAP93216.1 - 0.42 10.7 2.4 0.95 9.6 2.4 1.6 1 0 0 1 1 1 0 PHD-finger ANAPC3 PF12895.7 GAP93217.1 - 2e-27 95.2 19.2 5.4e-23 81.0 0.5 5.5 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAP93217.1 - 2.4e-27 92.8 26.1 0.00031 20.6 0.0 10.3 11 0 0 11 11 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 GAP93217.1 - 2.1e-26 90.6 14.9 3.7e-05 23.4 0.9 9.9 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 GAP93217.1 - 4.4e-24 84.8 16.9 0.0017 18.8 0.4 7.5 5 2 3 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 GAP93217.1 - 3.7e-19 68.8 19.9 7.9e-10 38.9 0.7 8.7 7 2 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 GAP93217.1 - 4.6e-18 65.6 19.2 3.7e-07 30.7 2.8 8.9 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 GAP93217.1 - 8.4e-18 63.5 22.2 0.0079 16.9 0.1 8.9 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAP93217.1 - 7.4e-15 53.8 10.1 0.0069 16.5 0.3 9.3 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAP93217.1 - 2.5e-12 46.2 10.3 0.00038 20.2 0.2 6.5 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 GAP93217.1 - 4.6e-12 45.4 12.6 0.019 14.6 0.6 7.6 7 1 1 8 8 8 4 TPR repeat TPR_6 PF13174.6 GAP93217.1 - 6.6e-12 45.3 12.5 0.43 11.3 0.2 8.6 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAP93217.1 - 1.6e-10 40.3 20.2 0.62 10.2 0.1 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 GAP93217.1 - 0.00011 22.3 12.0 0.027 14.6 1.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 GAP93217.1 - 0.0015 18.3 7.6 1.9 8.2 0.1 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat-like domain PPR PF01535.20 GAP93217.1 - 0.0023 18.1 0.1 2.5 8.6 0.0 4.6 4 0 0 4 4 4 1 PPR repeat Coatomer_E PF04733.14 GAP93217.1 - 0.0023 17.4 0.2 19 4.6 0.0 3.7 3 1 1 4 4 4 0 Coatomer epsilon subunit Cohesin_load PF10345.9 GAP93217.1 - 0.0024 16.4 0.1 2.1 6.7 0.0 3.2 3 0 0 3 3 3 1 Cohesin loading factor MIT PF04212.18 GAP93217.1 - 0.0074 16.3 2.2 23 5.1 0.0 5.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 GAP93217.1 - 0.016 15.8 12.3 1.6 9.6 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 GAP93217.1 - 0.025 14.9 9.2 0.1 12.9 1.0 4.7 4 2 2 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 GAP93217.1 - 0.52 10.8 12.3 30 5.3 0.4 6.8 8 1 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 GAP93217.1 - 0.53 10.4 10.5 19 5.5 0.2 5.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Rep_fac_C PF08542.11 GAP93218.1 - 8.7e-24 83.7 0.0 2e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 GAP93218.1 - 6.7e-12 45.5 0.0 2.6e-08 33.8 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 GAP93218.1 - 2.7e-11 44.0 0.0 5.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 GAP93218.1 - 3.1e-07 30.5 0.0 7.4e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 GAP93218.1 - 1.8e-06 28.4 0.0 9.5e-05 22.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 GAP93218.1 - 7.2e-05 22.6 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 GAP93218.1 - 8.2e-05 22.9 0.1 0.12 12.6 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 GAP93218.1 - 0.00015 21.6 0.0 0.00037 20.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 GAP93218.1 - 0.00015 21.6 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 GAP93218.1 - 0.0033 17.4 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 GAP93218.1 - 0.0034 16.8 0.0 0.023 14.1 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 GAP93218.1 - 0.0052 15.8 0.0 0.0097 14.9 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DNA_pol3_delta PF06144.13 GAP93218.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_11 PF13086.6 GAP93218.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 GAP93218.1 - 0.019 14.9 0.0 0.066 13.1 0.0 1.9 2 0 0 2 2 2 0 NTPase KTI12 PF08433.10 GAP93218.1 - 0.027 13.9 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TniB PF05621.11 GAP93218.1 - 0.029 13.8 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_assoc_2 PF16193.5 GAP93218.1 - 0.03 14.7 0.1 0.091 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA C-terminal domain DEAD PF00270.29 GAP93218.1 - 0.031 14.1 0.1 0.95 9.2 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 GAP93218.1 - 0.032 14.6 0.1 0.094 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 GAP93218.1 - 0.045 13.5 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 GAP93218.1 - 0.079 12.7 0.1 0.29 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 GAP93218.1 - 0.094 12.3 0.1 1 8.9 0.1 2.3 2 1 1 3 3 3 0 AAA domain DNA_pol3_gamma3 PF12169.8 GAP93218.1 - 0.15 12.0 0.3 1.6 8.6 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III ArgJ PF01960.18 GAP93219.1 - 2.9e-142 473.8 4.9 3.3e-142 473.7 4.9 1.0 1 0 0 1 1 1 1 ArgJ family NUDIX PF00293.28 GAP93220.1 - 1.1e-08 35.2 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 GAP93220.1 - 0.0022 17.9 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) DER1 PF04511.15 GAP93221.1 - 2.8e-23 82.9 7.0 3.2e-23 82.7 7.0 1.0 1 0 0 1 1 1 1 Der1-like family DAO PF01266.24 GAP93224.1 - 5.6e-46 157.7 3.3 6.5e-46 157.5 3.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 GAP93224.1 - 0.0002 20.8 0.2 0.00026 20.4 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 GAP93224.1 - 0.00035 19.8 4.1 0.00095 18.4 4.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 GAP93224.1 - 0.00038 19.8 2.2 0.00082 18.7 0.4 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 GAP93224.1 - 0.00048 19.5 0.5 0.00074 18.9 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 GAP93224.1 - 0.0008 18.7 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 GAP93224.1 - 0.0034 16.2 0.5 0.18 10.5 0.6 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 GAP93224.1 - 0.0069 16.6 0.1 0.016 15.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 GAP93224.1 - 0.034 14.2 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 GAP93224.1 - 0.039 13.2 0.1 0.061 12.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 GAP93224.1 - 0.069 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 GAP93224.1 - 0.28 10.2 0.7 0.38 9.8 0.7 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 GAP93224.1 - 0.28 11.8 1.1 0.99 10.0 0.6 2.1 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase CN_hydrolase PF00795.22 GAP93225.1 - 8.8e-15 54.7 0.0 2.5e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Ago_hook PF10427.9 GAP93226.1 - 0.052 14.1 0.1 0.073 13.6 0.1 1.2 1 0 0 1 1 1 0 Argonaute hook Protocadherin PF08374.11 GAP93226.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protocadherin DKCLD PF08068.12 GAP93227.1 - 2.7e-32 110.6 0.2 1.2e-30 105.3 0.2 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 GAP93227.1 - 1.8e-23 83.6 0.3 1.6e-20 74.0 0.3 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 GAP93227.1 - 3.4e-23 81.6 0.9 6.4e-23 80.7 0.9 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 GAP93227.1 - 5.6e-21 74.3 1.2 1.1e-20 73.3 1.2 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 GAP93227.1 - 0.0051 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain SKG6 PF08693.10 GAP93228.1 - 0.0032 16.8 2.0 0.0074 15.7 2.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Phage_Coat_B PF05356.11 GAP93228.1 - 0.049 13.5 0.5 0.12 12.3 0.5 1.6 1 0 0 1 1 1 0 Phage Coat protein B Adeno_E3_CR2 PF02439.15 GAP93228.1 - 0.12 12.2 0.7 0.23 11.3 0.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Tyrosinase PF00264.20 GAP93229.1 - 3.4e-49 168.1 2.4 6.6e-49 167.2 2.4 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF1996 PF09362.10 GAP93230.1 - 1.7e-77 260.6 3.8 2.2e-77 260.2 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NmrA PF05368.13 GAP93231.1 - 1.5e-26 93.4 0.1 2e-26 93.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP93231.1 - 7.6e-22 78.1 0.2 2.5e-20 73.1 0.0 2.1 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 GAP93231.1 - 0.00039 20.7 0.4 0.057 13.7 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 GAP93231.1 - 0.0011 18.5 0.0 0.04 13.4 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 GAP93231.1 - 0.0085 16.7 0.1 0.025 15.1 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pou PF00157.17 GAP93231.1 - 0.012 15.6 0.1 0.04 13.9 0.1 1.8 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain NAD_binding_2 PF03446.15 GAP93231.1 - 0.016 15.4 0.1 0.079 13.1 0.0 2.2 2 2 1 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase TTRAP PF14203.6 GAP93231.1 - 0.13 12.3 0.5 0.84 9.7 0.2 2.4 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein adh_short PF00106.25 GAP93232.1 - 5.4e-44 150.0 0.0 6.9e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 GAP93232.1 - 2.5e-30 105.8 0.0 3.1e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 GAP93232.1 - 2.1e-09 37.6 0.1 4.7e-09 36.4 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP93232.1 - 0.019 14.4 0.1 0.043 13.3 0.0 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Nuc_sug_transp PF04142.15 GAP93234.1 - 1.1e-07 31.3 0.3 1.7e-07 30.7 0.3 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAP93234.1 - 4.1e-07 30.2 26.4 0.00043 20.5 9.7 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 GAP93234.1 - 0.00037 19.9 2.3 0.00037 19.9 2.3 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family PDR_assoc PF08370.11 GAP93234.1 - 0.0028 17.3 5.3 2.4 7.9 0.2 3.6 3 0 0 3 3 3 3 Plant PDR ABC transporter associated UAA PF08449.11 GAP93234.1 - 0.0031 16.8 7.2 0.0055 16.0 7.2 1.3 1 0 0 1 1 1 1 UAA transporter family Yippee-Mis18 PF03226.14 GAP93235.1 - 9.7e-17 61.1 0.5 1.2e-16 60.8 0.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 GAP93235.1 - 0.0021 18.3 1.3 0.0034 17.6 1.3 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I zf-RRPl_C4 PF17026.5 GAP93235.1 - 0.031 14.4 1.8 0.043 13.9 1.2 1.5 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type HNH_5 PF14279.6 GAP93235.1 - 0.041 13.7 2.5 0.1 12.4 0.1 2.1 2 0 0 2 2 2 0 HNH endonuclease Ferric_reduct PF01794.19 GAP93236.1 - 6.2e-22 78.0 9.5 6.2e-22 78.0 9.5 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 GAP93236.1 - 3.1e-19 69.6 0.0 5e-11 43.0 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 GAP93236.1 - 1.2e-15 57.6 0.0 6.9e-14 51.9 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain DUF1206 PF06724.11 GAP93236.1 - 0.56 10.3 0.1 0.56 10.3 0.1 4.3 6 0 0 6 6 6 0 Domain of Unknown Function (DUF1206) CLU PF13236.6 GAP93238.1 - 3.4e-74 249.4 0.0 5.8e-74 248.6 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 GAP93238.1 - 1.2e-49 168.7 0.0 3.3e-49 167.3 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 GAP93238.1 - 1.1e-23 83.4 0.0 2.5e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 GAP93238.1 - 1.2e-23 83.2 18.0 6.6e-11 42.4 0.8 4.5 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 GAP93238.1 - 1.4e-21 75.7 1.3 5.9e-06 26.0 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 GAP93238.1 - 0.00013 21.9 4.4 0.025 14.8 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.12 GAP93238.1 - 0.00031 20.8 0.0 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 GAP93238.1 - 0.00089 19.2 7.7 0.068 13.3 0.1 4.2 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 GAP93238.1 - 0.0013 18.8 0.1 0.093 12.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 GAP93238.1 - 0.0019 18.0 2.1 0.084 12.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat CPSF100_C PF13299.6 GAP93238.1 - 0.0047 17.1 0.7 0.0047 17.1 0.7 3.0 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal TPR_7 PF13176.6 GAP93238.1 - 0.014 15.4 2.9 15 5.9 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Vfa1 PF08432.10 GAP93238.1 - 1.6 9.0 8.7 0.34 11.2 3.5 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Adaptin_binding PF10199.9 GAP93238.1 - 2.9 8.5 10.7 1.4 9.6 5.9 2.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 TPR_14 PF13428.6 GAP93238.1 - 5.4 8.1 7.8 7.1 7.7 0.3 4.1 3 1 1 4 4 3 0 Tetratricopeptide repeat Forkhead PF00250.18 GAP93239.1 - 3.8e-33 113.6 0.2 6.4e-33 112.9 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 GAP93239.1 - 2.1e-06 28.0 0.0 4.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain STE PF02200.16 GAP93241.1 - 2e-56 189.1 0.1 4.5e-56 188.0 0.1 1.6 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.26 GAP93241.1 - 2.6e-10 40.1 12.5 3.6e-06 27.1 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 GAP93241.1 - 6.4e-08 32.8 9.8 0.00025 21.6 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 GAP93241.1 - 9.9e-07 28.9 4.5 9.9e-07 28.9 4.5 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 GAP93241.1 - 0.0008 19.6 0.7 0.0085 16.4 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 GAP93241.1 - 0.0037 17.2 0.3 0.0037 17.2 0.3 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 GAP93241.1 - 0.023 14.9 0.2 0.058 13.7 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon zf-Di19 PF05605.12 GAP93241.1 - 0.3 11.4 3.3 0.56 10.5 3.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding AhpC-TSA_2 PF13911.6 GAP93242.1 - 8e-08 32.4 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 GAP93242.1 - 7.4e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 GAP93242.1 - 0.08 12.7 0.0 0.7 9.6 0.0 1.9 2 0 0 2 2 2 0 Redoxin Tubulin_3 PF14881.6 GAP93243.1 - 2.3e-76 255.5 1.2 4.5e-75 251.3 0.8 2.4 2 1 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 GAP93243.1 - 2.2e-42 144.1 0.0 5e-42 142.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 GAP93243.1 - 9e-05 22.8 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Glyco_hydro_35 PF01301.19 GAP93244.1 - 3.6e-87 293.0 0.1 5.5e-87 292.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 GAP93244.1 - 9.5e-53 177.6 1.5 1.8e-31 109.0 0.1 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 GAP93244.1 - 2.3e-34 118.8 0.0 1.2e-33 116.4 0.0 2.2 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 GAP93244.1 - 5.4e-16 57.9 0.1 2.6e-15 55.8 0.0 2.2 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 Chorismate_bind PF00425.18 GAP93245.1 - 7.3e-25 88.0 0.0 7.1e-20 71.6 0.0 2.6 3 0 0 3 3 3 2 chorismate binding enzyme GATase PF00117.28 GAP93245.1 - 6.9e-20 71.6 0.0 2.9e-19 69.6 0.0 2.0 2 1 0 2 2 2 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 GAP93245.1 - 4.5e-15 56.1 0.0 1.2e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 GAP93245.1 - 0.00079 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 DUF3397 PF11877.8 GAP93246.1 - 0.029 14.6 1.2 0.029 14.6 1.2 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3397) Yip1 PF04893.17 GAP93247.1 - 4.2e-12 46.1 21.3 1.2e-11 44.7 21.4 1.7 1 1 1 2 2 2 1 Yip1 domain DDDD PF10161.9 GAP93247.1 - 0.023 14.4 0.1 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Kelch_5 PF13854.6 GAP93248.1 - 1.4e-12 47.3 5.5 5.3e-12 45.4 0.3 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 GAP93248.1 - 4.2e-06 26.9 5.6 0.019 15.2 0.2 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 GAP93248.1 - 4.8e-06 26.5 3.9 0.16 12.0 0.1 5.4 7 1 0 7 7 7 2 Galactose oxidase, central domain Kelch_1 PF01344.25 GAP93248.1 - 6.2e-05 22.5 0.7 0.0063 16.1 0.0 4.5 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 GAP93248.1 - 6.3e-05 23.2 9.4 0.0032 17.7 0.1 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain SPX PF03105.19 GAP93249.1 - 1.9 8.3 5.0 4.4 7.1 5.0 1.5 1 0 0 1 1 1 0 SPX domain ThiF PF00899.21 GAP93250.1 - 1.2e-111 371.9 0.0 2e-75 253.3 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 GAP93250.1 - 3.6e-88 295.7 0.8 3.6e-88 295.7 0.8 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 GAP93250.1 - 5.6e-31 106.6 0.1 1.3e-30 105.3 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 GAP93250.1 - 1e-28 99.9 0.1 2.6e-28 98.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin fold domain E1_4HB PF16191.5 GAP93250.1 - 1.3e-19 70.1 0.1 5.4e-19 68.2 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle GST_N_2 PF13409.6 GAP93251.1 - 9.8e-21 73.8 0.0 1.9e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 GAP93251.1 - 6.9e-14 51.6 0.1 1.5e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 GAP93251.1 - 1.7e-05 25.1 0.0 0.058 13.8 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP93251.1 - 0.0016 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAP93251.1 - 0.19 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RIBIOP_C PF04950.12 GAP93252.1 - 4.2e-87 292.3 0.0 4.2e-87 292.3 0.0 2.1 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 GAP93252.1 - 1.4e-27 95.6 0.0 3.6e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 GAP93252.1 - 1.9e-05 25.1 0.4 0.00017 22.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP93252.1 - 2.4e-05 24.6 0.8 5.1e-05 23.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 GAP93252.1 - 3.2e-05 24.1 2.6 0.0001 22.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 GAP93252.1 - 0.00018 21.9 0.1 0.00041 20.8 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 GAP93252.1 - 0.001 18.7 0.0 0.37 10.3 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 GAP93252.1 - 0.0011 19.0 0.1 0.0032 17.5 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 GAP93252.1 - 0.0013 19.2 0.3 0.0051 17.3 0.0 2.1 2 0 0 2 2 1 1 ABC transporter NACHT PF05729.12 GAP93252.1 - 0.0027 17.7 0.1 0.0076 16.2 0.1 1.9 1 1 0 1 1 1 1 NACHT domain Roc PF08477.13 GAP93252.1 - 0.0032 17.7 0.2 0.053 13.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 GAP93252.1 - 0.0084 15.8 0.0 0.0084 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 GAP93252.1 - 0.0088 16.0 0.4 0.021 14.8 0.0 1.7 2 0 0 2 2 1 1 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 GAP93252.1 - 0.0094 16.3 0.1 0.021 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 GAP93252.1 - 0.012 16.1 0.1 0.012 16.1 0.1 3.6 4 1 0 4 4 2 0 AAA domain NB-ARC PF00931.22 GAP93252.1 - 0.015 14.5 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 GAP93252.1 - 0.018 15.0 0.1 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 GAP93252.1 - 0.035 14.2 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 GAP93252.1 - 0.036 13.6 0.1 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 GAP93252.1 - 0.038 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 GAP93252.1 - 0.045 13.6 0.1 0.16 11.8 0.0 1.9 1 1 1 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 GAP93252.1 - 0.053 13.8 0.1 0.053 13.8 0.1 2.1 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 GAP93252.1 - 0.059 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 GAP93252.1 - 0.062 13.7 0.1 0.062 13.7 0.1 2.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 GAP93252.1 - 0.071 13.1 0.0 0.45 10.5 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAP93252.1 - 0.082 12.4 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 GAP93252.1 - 0.09 12.7 0.4 0.17 11.8 0.4 1.4 1 0 0 1 1 1 0 NTPase Wzy_C_2 PF11846.8 GAP93252.1 - 0.37 10.7 1.5 0.6 10.0 0.6 1.7 2 0 0 2 2 1 0 Virulence factor membrane-bound polymerase, C-terminal AAA_11 PF13086.6 GAP93252.1 - 2.2 8.0 10.1 1.2 8.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain Inhibitor_I9 PF05922.16 GAP93253.1 - 1.3e-12 48.2 0.1 1.8e-12 47.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF5004 PF16395.5 GAP93253.1 - 0.051 13.6 0.0 0.059 13.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5004) BCDHK_Adom3 PF10436.9 GAP93254.1 - 2.2e-44 151.2 0.0 2.8e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 GAP93254.1 - 2.1e-11 44.3 0.0 1.5e-10 41.6 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 GAP93254.1 - 0.026 14.5 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Chitin_synth_2 PF03142.15 GAP93255.1 - 9.2e-227 753.8 0.1 1.3e-226 753.3 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 GAP93255.1 - 6.3e-16 58.0 1.8 4.9e-15 55.2 2.3 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 GAP93255.1 - 7.2e-14 52.2 0.0 2.6e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 GAP93255.1 - 7.7e-14 52.1 3.0 7.7e-14 52.1 3.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 GAP93255.1 - 1.3e-10 41.3 0.3 1.8e-08 34.4 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Myosin_head PF00063.21 GAP93255.1 - 1.9e-07 29.7 0.0 3.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 GAP93255.1 - 4.8e-05 22.9 0.0 0.0021 17.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 GAP93255.1 - 0.00059 19.7 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.15 GAP93256.1 - 8.4e-250 829.8 0.7 1.4e-249 829.1 0.6 1.4 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.21 GAP93256.1 - 1.1e-76 258.5 0.0 1.4e-75 254.8 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 GAP93256.1 - 7.5e-17 61.0 0.1 2.2e-16 59.5 0.1 1.9 1 0 0 1 1 1 1 DEK C terminal domain Cyt-b5 PF00173.28 GAP93256.1 - 1.4e-15 57.2 0.8 1.4e-11 44.3 0.1 3.5 3 1 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 GAP93256.1 - 3.2e-13 50.1 4.2 3.2e-13 50.1 4.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 GAP93256.1 - 7.6e-12 45.6 0.0 6.7e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 GAP93256.1 - 1.3e-06 28.3 0.0 0.0013 18.6 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 2 AAA_16 PF13191.6 GAP93256.1 - 0.0052 17.2 0.4 0.018 15.4 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_7 PF12775.7 GAP93256.1 - 0.014 14.9 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyco_transf_21 PF13506.6 GAP93256.1 - 0.014 14.8 0.1 0.043 13.3 0.1 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 21 AAA_29 PF13555.6 GAP93256.1 - 0.055 13.2 0.0 0.21 11.3 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 GAP93256.1 - 0.06 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SRPRB PF09439.10 GAP93256.1 - 0.072 12.5 0.5 0.32 10.4 0.5 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 GAP93256.1 - 0.072 12.7 0.0 0.54 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 GAP93256.1 - 0.14 12.6 0.1 0.35 11.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 GAP93256.1 - 0.24 11.7 0.4 0.76 10.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain Na_Ca_ex PF01699.24 GAP93257.1 - 2.9e-25 89.0 24.5 3e-15 56.5 5.5 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Otopetrin PF03189.13 GAP93257.1 - 8 5.2 7.9 2.4 6.9 4.8 1.6 2 0 0 2 2 2 0 Otopetrin GPI-anchored PF10342.9 GAP93258.1 - 0.0014 19.4 0.0 0.0022 18.7 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family F-box-like PF12937.7 GAP93259.1 - 0.00097 19.0 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 GAP93259.1 - 0.0064 16.3 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain TT_ORF2 PF02957.15 GAP93259.1 - 1.1 10.2 4.2 0.48 11.4 0.2 2.1 2 0 0 2 2 2 0 TT viral ORF2 Cupin_2 PF07883.11 GAP93260.1 - 9.2e-08 31.7 0.0 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 GAP93260.1 - 0.025 14.3 0.2 0.04 13.6 0.2 1.4 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 GAP93260.1 - 0.052 13.3 0.3 0.15 11.7 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF861) Amidase PF01425.21 GAP93261.1 - 2.4e-24 86.1 0.2 3.8e-23 82.2 0.5 2.0 2 0 0 2 2 2 2 Amidase CoA_transf_3 PF02515.17 GAP93263.1 - 8.8e-36 123.8 0.2 2.7e-32 112.3 0.2 2.5 2 1 0 2 2 2 2 CoA-transferase family III Glyco_hydro_12 PF01670.16 GAP93264.1 - 2.4e-37 129.0 9.1 1.9e-28 100.0 1.6 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 12 GFO_IDH_MocA PF01408.22 GAP93265.1 - 2.1e-12 47.9 0.0 5e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAP93265.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GST_N_3 PF13417.6 GAP93266.1 - 9.9e-14 51.5 0.0 1.8e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 GAP93266.1 - 2.1e-12 47.2 0.0 4.4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 GAP93266.1 - 3.5e-11 43.2 0.0 9.6e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 GAP93266.1 - 9.2e-09 35.4 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 GAP93266.1 - 1.2e-08 35.1 0.0 2.7e-08 33.9 0.0 1.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 GAP93266.1 - 0.0044 17.0 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 GAP93266.1 - 0.013 16.2 0.0 0.042 14.6 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain MutL_C PF08676.11 GAP93267.1 - 6.5e-23 81.1 0.2 2.5e-22 79.2 0.2 2.0 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 GAP93267.1 - 2.3e-18 66.0 0.0 5.5e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 GAP93267.1 - 2.1e-12 47.0 0.3 6.2e-11 42.3 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 GAP93267.1 - 1.4e-07 32.0 0.0 4.2e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGAP1 PF07819.13 GAP93268.1 - 5.8e-92 307.6 0.0 8.2e-92 307.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 GAP93268.1 - 3.5e-05 24.5 0.0 0.00013 22.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 GAP93268.1 - 0.00012 21.8 0.0 0.00038 20.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 GAP93268.1 - 0.0066 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 GAP93268.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 GAP93268.1 - 0.064 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Epiglycanin_C PF14654.6 GAP93268.1 - 3.4 7.8 6.2 5.6 7.1 0.1 2.8 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region MFS_1 PF07690.16 GAP93269.1 - 2e-15 56.6 45.3 7.8e-15 54.6 16.7 3.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 GAP93269.1 - 9.8e-11 41.6 3.0 9.8e-11 41.6 3.0 1.9 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.15 GAP93270.1 - 2.4e-162 540.8 8.1 2.7e-162 540.6 8.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF809 PF05663.11 GAP93270.1 - 0.12 12.5 0.4 0.34 11.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Cys_Met_Meta_PP PF01053.20 GAP93271.1 - 4.6e-138 459.9 0.1 5.3e-138 459.7 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 GAP93271.1 - 1.3e-06 27.8 0.0 2.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 GAP93271.1 - 8.8e-06 24.9 0.0 0.00014 20.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 GAP93271.1 - 3.9e-05 22.4 0.2 0.00011 20.8 0.2 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 GAP93271.1 - 0.0035 16.7 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 GAP93271.1 - 0.0042 16.0 0.1 0.0067 15.3 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 GAP93271.1 - 0.052 12.8 0.2 0.16 11.3 0.1 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase AAA PF00004.29 GAP93272.1 - 3.3e-38 131.1 0.0 6.3e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 GAP93272.1 - 1.9e-08 34.0 0.0 3.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 GAP93272.1 - 1.4e-06 28.8 0.2 0.00025 21.5 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 GAP93272.1 - 3e-06 27.3 0.0 7.6e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 GAP93272.1 - 9.3e-06 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 GAP93272.1 - 7.7e-05 22.9 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 GAP93272.1 - 8.1e-05 22.6 0.1 0.00082 19.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 GAP93272.1 - 9.3e-05 22.7 0.1 0.007 16.6 0.0 2.8 1 1 2 3 3 3 1 AAA domain TniB PF05621.11 GAP93272.1 - 0.00042 19.8 0.0 0.92 8.9 0.0 2.4 1 1 1 2 2 2 2 Bacterial TniB protein AAA_33 PF13671.6 GAP93272.1 - 0.00089 19.4 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 GAP93272.1 - 0.0013 18.1 0.1 0.0039 16.6 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 GAP93272.1 - 0.0032 17.8 0.0 0.0085 16.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 GAP93272.1 - 0.004 17.7 0.1 0.011 16.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 GAP93272.1 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 GAP93272.1 - 0.0081 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 GAP93272.1 - 0.011 15.4 0.1 0.086 12.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 GAP93272.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 GAP93272.1 - 0.017 15.0 0.0 0.045 13.7 0.0 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_17 PF13207.6 GAP93272.1 - 0.018 15.5 0.1 0.17 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 GAP93272.1 - 0.021 14.8 0.0 0.12 12.2 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 GAP93272.1 - 0.023 14.0 0.1 0.077 12.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 GAP93272.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 GAP93272.1 - 0.027 13.7 0.0 0.24 10.5 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.13 GAP93272.1 - 0.036 13.3 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain DUF815 PF05673.13 GAP93272.1 - 0.036 13.2 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 GAP93272.1 - 0.038 14.5 0.0 0.074 13.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 GAP93272.1 - 0.046 14.0 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 GAP93272.1 - 0.052 13.7 0.0 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 GAP93272.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 GAP93272.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Guanylate_kin PF00625.21 GAP93272.1 - 0.09 12.5 0.1 3.5 7.3 0.0 2.8 2 1 0 2 2 2 0 Guanylate kinase Viral_helicase1 PF01443.18 GAP93272.1 - 0.093 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 GAP93272.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein GMC_oxred_N PF00732.19 GAP93273.1 - 9.7e-55 186.0 0.0 1.3e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP93273.1 - 1.6e-31 109.7 0.1 3.3e-31 108.7 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 GAP93273.1 - 6.8e-06 25.4 0.0 0.018 14.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 GAP93273.1 - 4.8e-05 23.1 0.2 0.0046 16.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 GAP93273.1 - 7.8e-05 22.8 0.1 0.00022 21.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 GAP93273.1 - 0.031 13.5 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 GAP93273.1 - 0.035 13.2 0.1 0.054 12.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 GAP93273.1 - 0.084 11.6 0.1 0.4 9.3 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 GAP93273.1 - 0.19 10.9 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.23 GAP93275.1 - 3.8e-19 68.8 1.7 8.4e-19 67.7 1.7 1.6 1 1 0 1 1 1 1 FAD binding domain adh_short PF00106.25 GAP93276.1 - 9.8e-07 28.4 0.0 0.06 12.8 0.0 2.9 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 GAP93276.1 - 0.0037 17.2 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 GAP93276.1 - 0.04 13.4 0.0 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 GAP93276.1 - 0.2 10.8 0.0 0.56 9.3 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein p450 PF00067.22 GAP93277.1 - 1.8e-11 43.5 0.0 2.4e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ammonium_transp PF00909.21 GAP93278.1 - 1.4e-117 392.8 28.5 1.6e-117 392.6 28.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family C2 PF00168.30 GAP93279.1 - 7.5e-24 84.0 0.2 7.4e-12 45.5 0.0 2.9 3 0 0 3 3 3 2 C2 domain Methyltransf_25 PF13649.6 GAP93280.1 - 4e-07 30.6 0.1 6.4e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP93280.1 - 7e-06 26.6 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP93280.1 - 7.7e-06 25.8 0.0 1.1e-05 25.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP93280.1 - 7.8e-06 26.6 0.0 1.4e-05 25.7 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP93280.1 - 0.0079 16.0 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP93280.1 - 0.19 11.1 0.0 0.24 10.7 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Adap_comp_sub PF00928.21 GAP93281.1 - 2.4e-84 282.8 0.0 2.9e-84 282.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 GAP93281.1 - 0.00017 21.5 0.1 0.00031 20.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 GAP93281.1 - 0.08 12.4 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Glyco_hydro_6 PF01341.17 GAP93282.1 - 3.7e-107 358.6 1.6 4.8e-107 358.2 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 GAP93282.1 - 2.8e-13 49.6 15.7 1e-12 47.7 15.7 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain ABC_tran PF00005.27 GAP93283.1 - 2.6e-46 157.5 0.0 5.2e-22 78.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 GAP93283.1 - 2.7e-20 72.2 5.7 2.7e-20 72.2 5.7 2.8 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 GAP93283.1 - 2e-17 64.0 1.1 0.0014 18.5 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 GAP93283.1 - 4.2e-13 49.3 0.2 5e-05 22.8 0.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 GAP93283.1 - 1.4e-09 38.8 3.5 0.011 16.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 GAP93283.1 - 2.7e-08 33.4 0.0 0.0037 17.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 GAP93283.1 - 1.7e-07 31.3 0.3 0.0017 18.3 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 GAP93283.1 - 1.1e-06 28.7 0.0 0.041 13.6 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 GAP93283.1 - 1.1e-06 29.2 0.1 0.056 14.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 GAP93283.1 - 3.1e-06 27.7 0.0 0.04 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 GAP93283.1 - 3.6e-06 27.3 1.6 1.5 9.2 0.0 3.6 3 0 0 3 3 3 2 RNA helicase MMR_HSR1 PF01926.23 GAP93283.1 - 3.9e-06 26.9 0.0 0.018 15.1 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 GAP93283.1 - 9.7e-06 25.9 0.0 0.097 12.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 GAP93283.1 - 1.6e-05 25.3 0.1 0.25 11.7 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 GAP93283.1 - 3.4e-05 23.9 0.2 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 GAP93283.1 - 3.9e-05 23.6 0.1 0.17 11.8 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 GAP93283.1 - 4.3e-05 23.8 0.0 0.02 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 GAP93283.1 - 0.00066 19.7 0.0 1.6 8.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 GAP93283.1 - 0.001 18.3 0.1 2.7 7.1 0.0 3.1 3 0 0 3 3 3 2 NB-ARC domain AAA_33 PF13671.6 GAP93283.1 - 0.001 19.2 0.1 0.51 10.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 GAP93283.1 - 0.0019 18.2 0.3 1.2 8.9 0.0 3.1 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 GAP93283.1 - 0.0021 17.8 0.4 0.36 10.5 0.1 3.0 2 1 0 2 2 2 1 AAA domain DUF2813 PF11398.8 GAP93283.1 - 0.0035 16.7 0.2 1.1 8.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) AAA_24 PF13479.6 GAP93283.1 - 0.0038 17.0 0.8 2.1 8.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 GAP93283.1 - 0.004 16.8 0.0 1.1 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 GAP93283.1 - 0.0041 17.3 0.1 4.9 7.4 0.1 3.0 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 GAP93283.1 - 0.0055 17.1 0.5 1.4 9.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 GAP93283.1 - 0.01 16.0 0.1 4.8 7.2 0.0 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 GAP93283.1 - 0.012 15.5 0.3 2 8.3 0.3 2.8 2 0 0 2 2 2 0 NTPase GST_C_3 PF14497.6 GAP93283.1 - 0.013 15.7 0.2 0.034 14.4 0.2 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_25 PF13481.6 GAP93283.1 - 0.015 14.9 0.4 0.79 9.3 0.0 3.3 4 0 0 4 4 4 0 AAA domain Dynamin_N PF00350.23 GAP93283.1 - 0.033 14.3 1.0 18 5.4 0.0 3.7 3 1 1 4 4 4 0 Dynamin family AAA_7 PF12775.7 GAP93283.1 - 0.033 13.7 0.0 2.1 7.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 GAP93283.1 - 0.039 13.9 0.3 10 6.1 0.0 3.0 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 GAP93283.1 - 0.04 13.1 0.5 3.2 6.8 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF815) DAP3 PF10236.9 GAP93283.1 - 0.053 12.7 1.0 8.7 5.4 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 FeoB_N PF02421.18 GAP93283.1 - 0.07 12.6 0.0 6.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 GAP93283.1 - 0.085 12.6 0.7 9.5 6.0 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 GAP93283.1 - 0.25 10.3 2.5 17 4.2 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SNF2_N PF00176.23 GAP93284.1 - 5.5e-64 216.1 2.3 9.2e-64 215.4 0.2 2.3 2 1 0 3 3 3 1 SNF2 family N-terminal domain DBINO PF13892.6 GAP93284.1 - 1.3e-47 161.5 16.3 1.3e-47 161.5 16.3 4.8 3 1 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 GAP93284.1 - 6.3e-20 71.6 0.0 1.4e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 GAP93284.1 - 1.1e-05 25.5 0.1 5.9e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Fe_hyd_lg_C PF02906.14 GAP93284.1 - 0.14 11.8 2.7 0.14 11.8 0.8 2.0 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Hydrophobin PF01185.18 GAP93287.1 - 1.6e-12 47.9 6.5 1.9e-12 47.6 6.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.12 GAP93287.1 - 3.6 8.4 10.8 4.7 8.0 1.4 3.0 3 0 0 3 3 3 0 Ion channel inhibitory toxin Lipase_3 PF01764.25 GAP93289.1 - 1.4e-12 47.6 0.0 2.8e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Piwi PF02171.17 GAP93292.1 - 1.7e-64 218.0 0.0 3.1e-64 217.1 0.0 1.4 1 1 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 GAP93292.1 - 3.3e-15 55.5 0.4 8.6e-15 54.2 0.4 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 GAP93292.1 - 1.4e-13 51.6 0.2 2.7e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 GAP93292.1 - 6.1e-10 39.3 0.0 1.4e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 GAP93292.1 - 7.7e-08 32.2 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Vint PF14623.6 GAP93293.1 - 3.8e-56 189.5 0.0 7.6e-56 188.5 0.0 1.5 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.6 GAP93293.1 - 3.9e-25 87.8 0.1 6.9e-25 87.0 0.1 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 GAP93293.1 - 6.1e-15 55.9 0.0 1.3e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 GAP93293.1 - 7.5e-11 42.6 0.2 1.5e-10 41.7 0.2 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 GAP93293.1 - 1.2e-08 35.1 0.2 1.7e-06 28.1 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain PRKCSH-like PF12999.7 GAP93294.1 - 2.8e-39 134.7 12.1 6.7e-24 84.6 1.2 3.4 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 GAP93294.1 - 4.6e-31 107.6 0.5 4.6e-31 107.6 0.5 2.1 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 GAP93294.1 - 2.8e-11 44.3 3.1 1.1e-10 42.4 3.1 2.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein TolA PF06519.11 GAP93294.1 - 0.0019 18.4 0.0 0.0086 16.2 0.0 2.1 2 0 0 2 2 2 1 TolA C-terminal Phage_GP20 PF06810.11 GAP93294.1 - 0.0045 16.8 1.5 0.0045 16.8 1.5 2.7 3 0 0 3 3 3 1 Phage minor structural protein GP20 CdvA PF18822.1 GAP93294.1 - 0.0073 16.1 4.4 0.0073 16.1 4.4 2.9 3 0 0 3 3 3 1 CdvA-like coiled-coil domain ATG27 PF09451.10 GAP93294.1 - 0.015 15.2 0.3 0.031 14.1 0.3 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF5082 PF16888.5 GAP93294.1 - 0.022 15.1 9.1 1.2 9.4 1.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) ABATE PF07336.11 GAP93294.1 - 0.072 13.8 0.4 9.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Putative stress-induced transcription regulator GP41 PF00517.17 GAP93294.1 - 0.086 12.7 1.8 0.44 10.4 0.9 2.1 2 0 0 2 2 2 0 Retroviral envelope protein NuA4 PF09340.10 GAP93294.1 - 2.1 8.3 6.1 20 5.2 0.3 2.7 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Jnk-SapK_ap_N PF09744.9 GAP93294.1 - 2.2 8.5 23.3 0.073 13.3 7.7 3.3 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 Prefoldin_2 PF01920.20 GAP93294.1 - 4.4 7.3 16.8 0.6 10.1 4.8 3.6 3 0 0 3 3 3 0 Prefoldin subunit Mod_r PF07200.13 GAP93294.1 - 4.5 7.4 15.7 0.66 10.1 2.6 3.2 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Fzo_mitofusin PF04799.13 GAP93294.1 - 9.4 5.8 11.6 36 3.9 2.4 3.1 3 0 0 3 3 3 0 fzo-like conserved region Rtf2 PF04641.12 GAP93295.1 - 1.8e-42 145.5 2.4 2.4e-42 145.1 2.4 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.6 GAP93295.1 - 0.00064 19.7 0.0 0.086 12.9 0.0 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.8 GAP93295.1 - 0.0039 17.0 0.1 0.07 13.0 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 GAP93295.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 GAP93295.1 - 0.014 15.7 1.0 0.094 13.1 0.1 2.6 2 1 1 3 3 3 0 Ring finger domain DiS_P_DiS PF06750.13 GAP93295.1 - 0.03 14.4 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-C3HC4_2 PF13923.6 GAP93295.1 - 0.083 12.7 0.7 0.8 9.6 0.0 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 GAP93295.1 - 0.15 11.9 0.1 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 RING-like zinc finger Prok-RING_4 PF14447.6 GAP93295.1 - 0.25 11.2 2.0 16 5.4 0.2 3.5 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 PPL5 PF18168.1 GAP93295.1 - 0.53 9.5 4.7 0.76 9.0 4.7 1.2 1 0 0 1 1 1 0 Prim-pol family 5 IHABP4_N PF16174.5 GAP93295.1 - 3.7 8.1 13.3 13 6.3 10.7 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal MAJIN PF15077.6 GAP93295.1 - 7.5 6.3 8.1 11 5.7 8.1 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein FAT PF02259.23 GAP93296.1 - 1.1e-128 429.3 5.1 2.2e-128 428.3 5.1 1.6 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 GAP93296.1 - 2.3e-77 258.4 2.8 1.1e-73 246.5 0.5 4.7 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 GAP93296.1 - 2.8e-72 243.6 0.0 4.8e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 GAP93296.1 - 1.7e-42 143.9 3.1 4e-42 142.7 0.7 2.9 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT PF02985.22 GAP93296.1 - 1.4e-15 56.1 11.3 0.013 15.7 0.0 12.0 12 0 0 12 12 12 2 HEAT repeat FATC PF02260.20 GAP93296.1 - 1.7e-13 50.1 0.2 5.4e-13 48.5 0.2 2.0 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 GAP93296.1 - 9.7e-12 45.1 10.4 0.0057 17.0 0.0 7.8 10 0 0 10 10 8 3 HEAT repeats HEAT_EZ PF13513.6 GAP93296.1 - 5.1e-10 39.6 19.5 0.0061 17.0 0.0 10.9 9 3 3 12 12 12 2 HEAT-like repeat Cnd1 PF12717.7 GAP93296.1 - 3.2e-07 30.5 0.3 0.25 11.3 0.0 5.7 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAP93296.1 - 2e-06 26.6 2.3 0.02 13.4 2.6 4.8 3 1 0 3 3 3 1 Adaptin N terminal region ANAPC3 PF12895.7 GAP93296.1 - 0.054 13.7 5.0 3 8.2 0.1 3.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Sec7_N PF12783.7 GAP93296.1 - 0.11 12.4 3.6 21 5.0 0.0 4.7 4 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Cohesin_HEAT PF12765.7 GAP93296.1 - 0.13 12.6 0.8 16 5.9 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion VirDNA-topo-I_N PF09266.10 GAP93296.1 - 0.19 11.9 0.0 0.49 10.6 0.0 1.7 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal Pex24p PF06398.11 GAP93299.1 - 1.2e-93 314.0 0.0 1.5e-93 313.7 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Sugar_tr PF00083.24 GAP93300.1 - 4.1e-09 35.8 0.4 4.5e-09 35.7 0.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 GAP93301.1 - 5.8e-75 252.9 15.8 6.5e-75 252.7 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 GAP93301.1 - 1.6e-22 79.9 29.2 2.6e-22 79.3 29.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4481 PF14800.6 GAP93301.1 - 0.22 11.0 1.1 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) MFS_1 PF07690.16 GAP93302.1 - 1.8e-23 83.0 41.7 4.4e-18 65.3 11.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP93302.1 - 1.5e-08 33.9 0.4 1.5e-08 33.9 0.4 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 GAP93302.1 - 0.0018 17.2 4.3 0.75 8.6 0.0 2.1 2 0 0 2 2 2 2 MFS_1 like family TRI12 PF06609.13 GAP93302.1 - 0.0092 14.4 0.3 0.018 13.5 0.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_71 PF03659.14 GAP93303.1 - 6.1e-117 390.6 0.4 7.2e-117 390.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 GCIP PF13324.6 GAP93304.1 - 2.3e-24 86.4 0.0 3.9e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting BTB PF00651.31 GAP93305.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain Pribosyl_synth PF14572.6 GAP93306.1 - 1.5e-41 142.5 2.6 1.3e-35 123.1 1.2 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 GAP93306.1 - 4.7e-33 113.6 0.0 1.5e-32 112.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 GAP93306.1 - 6.1e-14 51.8 0.2 1.1e-13 51.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PEX11 PF05648.14 GAP93307.1 - 1.2e-64 217.8 0.2 1.4e-64 217.6 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Spherulin4 PF12138.8 GAP93308.1 - 4.9e-39 134.4 0.0 6.8e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Spherulation-specific family 4 Ras PF00071.22 GAP93309.1 - 3.8e-54 182.7 0.0 4.3e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP93309.1 - 1.9e-21 76.5 0.0 2.8e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP93309.1 - 2.5e-06 27.1 0.0 3.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 GAP93310.1 - 1.1e-11 44.3 0.0 3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.6 GAP93311.1 - 2.6e-71 239.9 0.0 3.1e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 GAP93311.1 - 0.00012 21.9 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cu-oxidase PF00394.22 GAP93313.1 - 6e-27 94.7 0.1 3.5e-26 92.2 0.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 GAP93313.1 - 1e-25 90.1 0.1 2e-25 89.1 0.1 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 GAP93313.1 - 2.3e-05 24.1 5.5 0.054 13.2 0.4 3.2 2 2 0 2 2 2 2 Multicopper oxidase CorA PF01544.18 GAP93314.1 - 1.6e-07 30.9 1.1 6.6e-05 22.4 0.7 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Ank_2 PF12796.7 GAP93315.1 - 2.2e-45 153.1 0.0 1.3e-11 45.0 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP93315.1 - 5.3e-35 119.3 1.1 9.6e-10 38.8 0.2 7.3 4 3 4 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP93315.1 - 6.2e-33 112.4 3.5 2e-08 34.3 0.1 7.5 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 GAP93315.1 - 7.4e-32 108.4 1.4 0.00017 21.9 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 GAP93315.1 - 2.3e-30 101.2 0.0 0.026 15.1 0.0 9.9 10 0 0 10 10 10 7 Ankyrin repeat PNP_UDP_1 PF01048.20 GAP93315.1 - 2e-16 60.0 0.0 3.6e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily EMC1_C PF07774.13 GAP93316.1 - 1.8e-70 236.9 0.0 3.1e-70 236.2 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 GAP93316.1 - 1.5e-18 67.3 10.4 2.9e-15 56.5 1.2 3.3 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 GAP93316.1 - 0.00019 21.2 7.3 0.0028 17.5 0.1 5.3 7 0 0 7 7 7 1 PQQ enzyme repeat zf-PARP PF00645.18 GAP93317.1 - 1e-21 77.6 0.3 4e-21 75.7 0.3 2.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DTHCT PF08070.11 GAP93317.1 - 0.015 16.0 21.9 0.015 16.0 21.9 4.0 2 2 1 3 3 3 0 DTHCT (NUC029) region PI3_PI4_kinase PF00454.27 GAP93318.1 - 1e-48 166.3 0.0 1.9e-48 165.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 GAP93318.1 - 3.9e-36 125.0 1.7 7.8e-36 124.0 1.7 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.13 GAP93318.1 - 8.2e-29 99.5 5.1 2.8e-27 94.6 0.5 4.4 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 GAP93318.1 - 7e-17 61.0 0.0 2.1e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 FATC domain IFRD PF05004.13 GAP93318.1 - 0.056 12.5 0.1 0.45 9.6 0.0 2.6 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) COX16 PF14138.6 GAP93319.1 - 4.9e-34 116.7 0.3 9.6e-34 115.7 0.1 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 HTH_17 PF12728.7 GAP93319.1 - 0.021 15.0 0.1 0.029 14.6 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Smim3 PF17307.2 GAP93319.1 - 0.19 11.2 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Small integral membrane protein 3 Amidase PF01425.21 GAP93321.1 - 1.9e-48 165.6 0.3 5.5e-44 150.9 0.5 2.4 1 1 1 2 2 2 2 Amidase p450 PF00067.22 GAP93322.1 - 1.2e-50 172.7 0.0 2.4e-50 171.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 GAP93323.1 - 4e-11 42.7 12.0 1.2e-08 34.6 6.2 2.5 1 1 2 3 3 3 2 UbiA prenyltransferase family AMP-binding PF00501.28 GAP93324.1 - 3.1e-24 85.3 0.0 8.6e-24 83.9 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAP93324.1 - 2.4e-20 72.8 0.0 4e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 GAP93324.1 - 7.4e-05 23.0 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 GAP93324.1 - 0.0017 18.8 0.0 0.0049 17.3 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 GAP93324.1 - 0.0073 15.8 0.1 0.056 12.9 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 GAP93325.1 - 6.8e-21 74.9 0.2 3e-20 72.8 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 GAP93325.1 - 9.1e-05 22.6 0.0 0.00025 21.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 GAP93325.1 - 0.0039 16.5 0.1 0.16 11.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 GAP93325.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 GAP93325.1 - 0.011 16.3 0.0 0.031 14.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 GAP93325.1 - 0.03 13.2 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DUF747 PF05346.11 GAP93326.1 - 2.9e-118 395.0 6.4 3.6e-118 394.7 6.4 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family NP1-WLL PF11733.8 GAP93326.1 - 0.2 11.4 3.2 0.35 10.6 3.2 1.3 1 0 0 1 1 1 0 Non-capsid protein NP1 HemY_N PF07219.13 GAP93326.1 - 2.3 8.4 9.8 2 8.6 1.3 3.4 3 0 0 3 3 3 0 HemY protein N-terminus Beta-lactamase PF00144.24 GAP93327.1 - 1.6e-36 126.2 0.0 2.7e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DAO PF01266.24 GAP93328.1 - 3.1e-52 178.3 2.1 3.7e-52 178.1 2.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 GAP93328.1 - 0.00028 20.3 0.3 0.0014 17.9 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP93328.1 - 0.003 16.8 0.3 0.16 11.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP93328.1 - 0.0056 16.9 3.6 0.043 14.1 2.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 GAP93328.1 - 0.024 13.7 3.8 0.29 10.2 2.5 2.2 2 0 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.24 GAP93328.1 - 0.033 13.5 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 GAP93328.1 - 0.12 11.1 2.0 0.13 10.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 GAP93328.1 - 0.32 11.0 1.3 29 4.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Etmic-2 PF06670.11 GAP93328.1 - 0.65 8.9 3.5 0.26 10.2 0.5 1.7 2 0 0 2 2 2 0 Microneme protein Etmic-2 Glyoxalase_4 PF13669.6 GAP93330.1 - 0.036 14.3 0.0 0.045 14.0 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 GAP93330.1 - 0.056 13.5 0.1 0.073 13.2 0.1 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase PF00903.25 GAP93330.1 - 0.058 13.6 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2046 PF09755.9 GAP93331.1 - 0.0049 16.2 1.2 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) CENP-F_leu_zip PF10473.9 GAP93331.1 - 0.012 15.6 0.5 0.012 15.6 0.5 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GreA_GreB_N PF03449.15 GAP93331.1 - 0.028 14.6 1.0 0.072 13.2 1.0 1.7 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal THOC7 PF05615.13 GAP93331.1 - 0.21 11.8 5.2 1 9.7 1.6 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 DivIC PF04977.15 GAP93331.1 - 0.45 10.3 0.1 0.45 10.3 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator DegS PF05384.11 GAP93331.1 - 0.58 9.6 3.3 1.2 8.6 3.3 1.4 1 0 0 1 1 1 0 Sensor protein DegS DUF1996 PF09362.10 GAP93332.1 - 2.1e-46 158.8 0.2 2.6e-46 158.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RRM_1 PF00076.22 GAP93333.1 - 2.4e-07 30.5 0.1 4.4e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 GAP93333.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Gln_amidase PF15644.6 GAP93333.1 - 0.055 14.5 0.5 0.27 12.3 0.1 2.2 2 1 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase ANTH PF07651.16 GAP93333.1 - 0.068 12.2 0.1 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 ANTH domain RRM_3 PF08777.11 GAP93333.1 - 0.086 12.9 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 RNA binding motif MFS_1 PF07690.16 GAP93334.1 - 5.9e-17 61.6 45.8 4.7e-16 58.7 45.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3176 PF11374.8 GAP93337.1 - 1.7e-31 108.6 0.3 1.7e-31 108.6 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) HET PF06985.11 GAP93338.1 - 1.8e-36 125.6 0.1 2.8e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ThuA PF06283.11 GAP93339.1 - 3e-30 106.0 0.0 3.4e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation DUF4159 PF13709.6 GAP93339.1 - 0.14 11.6 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Amidase PF01425.21 GAP93341.1 - 1.2e-90 304.7 0.3 1.5e-90 304.3 0.3 1.1 1 0 0 1 1 1 1 Amidase Aldo_ket_red PF00248.21 GAP93342.1 - 5.6e-66 222.7 0.0 6.8e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TrkH PF02386.16 GAP93344.1 - 3.1e-96 322.8 2.2 2.6e-93 313.2 0.3 2.1 2 0 0 2 2 2 2 Cation transport protein KR PF08659.10 GAP93345.1 - 2e-51 174.4 0.1 3.7e-51 173.6 0.1 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 GAP93345.1 - 3.9e-50 170.8 0.0 5.9e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 GAP93345.1 - 4.3e-50 170.7 0.0 9.4e-50 169.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 GAP93345.1 - 4.7e-40 138.0 0.0 7.5e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP93345.1 - 3.7e-34 117.3 0.0 8.5e-34 116.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 GAP93345.1 - 1.4e-12 48.8 0.0 4.6e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 GAP93345.1 - 2.3e-12 47.0 0.0 6.5e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 GAP93345.1 - 1.5e-11 44.7 0.0 4.3e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 GAP93345.1 - 3.3e-10 39.8 0.0 7.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 GAP93345.1 - 1.6e-06 27.9 0.1 4.1e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 GAP93345.1 - 3.1e-06 27.5 1.2 5.8e-06 26.6 0.1 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 GAP93345.1 - 2.2e-05 24.2 0.3 7.6e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 GAP93345.1 - 1.8 8.5 4.7 0.25 11.2 0.3 1.9 2 0 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ANAPC8 PF04049.13 GAP93346.1 - 4.4e-34 117.5 0.0 1.1e-33 116.3 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 GAP93346.1 - 1.1e-18 66.2 15.3 6.7e-07 28.9 0.1 7.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 GAP93346.1 - 4.9e-17 60.6 8.1 0.00013 21.9 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 GAP93346.1 - 8e-14 50.6 22.3 0.00023 21.0 0.1 9.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 GAP93346.1 - 8e-12 45.3 10.8 0.056 13.7 0.0 6.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 GAP93346.1 - 4.6e-11 42.2 3.4 0.0014 18.3 0.5 4.1 2 2 2 4 4 4 3 TPR repeat TPR_14 PF13428.6 GAP93346.1 - 2.8e-09 37.0 24.5 0.054 14.3 0.3 7.7 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 GAP93346.1 - 5.6e-08 32.3 14.2 0.0044 16.9 0.3 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP93346.1 - 5.9e-08 32.8 13.7 0.0013 18.9 0.1 6.3 5 1 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 GAP93346.1 - 9.1e-05 22.9 23.4 0.02 15.4 0.0 7.0 6 2 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAP93346.1 - 0.00032 21.3 16.1 0.017 15.7 1.4 5.3 4 1 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAP93346.1 - 0.0031 17.8 10.7 0.69 10.4 0.3 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 GAP93346.1 - 0.012 15.4 6.7 1 9.4 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 GAP93346.1 - 0.16 11.0 0.0 0.45 9.5 0.0 1.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 GAP93346.1 - 1.7 8.8 8.6 11 6.3 0.0 4.6 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 GAP93346.1 - 3.1 8.6 10.0 2.7e+02 2.5 0.4 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat DCP1 PF06058.13 GAP93347.1 - 3.5e-26 91.4 0.0 6.1e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family TERB2 PF15101.6 GAP93347.1 - 0.13 12.3 6.5 0.2 11.7 6.5 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TFIIA PF03153.13 GAP93347.1 - 0.62 10.0 17.5 0.98 9.3 17.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 GAP93347.1 - 2.1 7.9 21.1 3.8 7.1 21.1 1.3 1 0 0 1 1 1 0 Spt20 family Exo_endo_phos PF03372.23 GAP93348.1 - 3.2e-08 33.4 0.0 7.8e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 GAP93349.1 - 6.8e-08 32.2 0.0 3.7e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 GAP93349.1 - 4.2e-06 26.3 0.0 7.1e-05 22.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_transf_15 PF01793.16 GAP93351.1 - 5.5e-78 262.5 9.9 2.2e-76 257.2 9.9 2.1 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Gly_transf_sug PF04488.15 GAP93352.1 - 7.1e-09 36.2 0.0 1.6e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 GAP93352.1 - 2.1e-05 24.0 0.0 0.00026 20.4 0.0 2.0 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 GAP93352.1 - 0.0011 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein OppC_N PF12911.7 GAP93352.1 - 0.025 14.5 2.7 0.04 13.9 0.1 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C AA_permease PF00324.21 GAP93354.1 - 1.5e-116 389.9 35.5 1.8e-116 389.6 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 GAP93354.1 - 1.8e-23 83.0 34.0 2.6e-23 82.5 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.11 GAP93354.1 - 0.98 9.4 8.4 0.059 13.3 1.6 2.3 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 PLDc_2 PF13091.6 GAP93355.1 - 2.3e-19 69.6 0.0 2.7e-13 50.0 0.0 3.7 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 GAP93355.1 - 0.0095 16.1 0.0 0.1 12.9 0.0 2.3 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.8 GAP93355.1 - 0.017 14.3 0.4 0.9 8.7 0.0 3.1 4 0 0 4 4 4 0 Archaeal transcriptional regulator TrmB p450 PF00067.22 GAP93357.1 - 1.5e-23 83.3 0.0 3.5e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 GAP93358.1 - 7.3e-11 41.6 37.5 1.3e-10 40.8 33.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF872 PF05915.12 GAP93358.1 - 0.22 11.7 3.3 0.98 9.6 0.1 3.0 2 2 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4307 PF14155.6 GAP93358.1 - 0.78 9.6 3.6 23 4.8 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) FeoB_associated PF12669.7 GAP93358.1 - 1.2 9.5 4.0 1.2e+02 3.2 0.0 3.5 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein p450 PF00067.22 GAP93359.1 - 4.1e-31 108.2 0.0 1.9e-30 106.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 GAP93360.1 - 1.3e-12 47.8 0.0 2.8e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 GAP93360.1 - 3.7e-05 23.6 0.0 0.00011 22.0 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 GAP93360.1 - 0.00022 22.3 0.0 0.00047 21.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.26 GAP93361.1 - 1.4e-75 254.2 0.0 6.5e-75 252.0 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 GAP93361.1 - 1e-73 248.3 0.1 2.4e-73 247.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 GAP93361.1 - 1.5e-65 221.7 0.0 2.6e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 GAP93361.1 - 3.8e-52 176.8 0.1 4.4e-51 173.3 0.1 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 GAP93361.1 - 3.8e-49 167.5 0.0 6.8e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 GAP93361.1 - 9.9e-43 146.8 0.2 2e-42 145.8 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 GAP93361.1 - 1.8e-27 95.7 0.0 7.4e-27 93.7 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 GAP93361.1 - 2.6e-20 72.5 0.2 7.1e-10 39.1 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 GAP93361.1 - 4.4e-20 71.9 0.0 1.7e-18 66.7 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 GAP93361.1 - 3e-18 66.4 0.0 1.4e-17 64.3 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 GAP93361.1 - 5.5e-15 55.8 0.0 1.5e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 GAP93361.1 - 1.9e-12 47.4 0.0 4.3e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP93361.1 - 1.7e-11 44.7 0.0 7.9e-11 42.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP93361.1 - 6.6e-10 39.0 0.0 2.5e-09 37.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 GAP93361.1 - 1.4e-09 37.7 0.1 4.2e-09 36.1 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_11 PF08241.12 GAP93361.1 - 2.3e-09 37.8 0.0 7.4e-09 36.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 GAP93361.1 - 1.9e-07 30.8 0.0 0.0039 16.7 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 GAP93361.1 - 1.3e-06 27.7 0.0 0.0036 16.3 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 GAP93361.1 - 2.6e-05 23.7 0.0 6.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 GAP93361.1 - 8.9e-05 22.0 0.1 0.0002 20.8 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 GAP93361.1 - 0.00045 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 GAP93361.1 - 0.0035 16.8 0.0 0.061 12.7 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 GAP93361.1 - 0.034 14.0 0.1 4.4 7.2 0.0 3.0 3 0 0 3 3 2 0 NAD(P)H-binding AMP-binding_C PF13193.6 GAP93361.1 - 0.067 14.2 0.5 0.44 11.6 0.1 2.8 2 0 0 2 2 1 0 AMP-binding enzyme C-terminal domain Methyltransf_33 PF10017.9 GAP93361.1 - 0.094 11.9 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent GFO_IDH_MocA PF01408.22 GAP93362.1 - 1.8e-19 70.7 0.3 3.4e-19 69.8 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 GAP93362.1 - 0.00074 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Fungal_trans_2 PF11951.8 GAP93362.1 - 0.017 13.9 0.1 0.026 13.4 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.22 GAP93363.1 - 1.4e-15 58.2 0.2 2.1e-15 57.6 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 GAP93363.1 - 0.032 14.9 0.1 0.056 14.1 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CDH-cyt PF16010.5 GAP93364.1 - 1.5e-56 191.0 1.8 1.8e-56 190.7 1.8 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Actin PF00022.19 GAP93365.1 - 3.5e-98 328.9 0.0 2.8e-97 325.9 0.0 1.9 1 1 0 1 1 1 1 Actin SBBP PF06739.11 GAP93365.1 - 0.071 13.1 0.1 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 Beta-propeller repeat F-box-like PF12937.7 GAP93367.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 GAP93367.1 - 0.042 13.8 0.2 0.57 10.1 0.0 2.5 2 1 0 2 2 2 0 F-box domain UFD1 PF03152.14 GAP93368.1 - 3e-26 92.0 0.0 3.8e-20 72.1 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 Tyrosinase PF00264.20 GAP93369.1 - 1.2e-33 117.3 4.8 1.2e-33 117.3 4.8 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase Methyltransf_2 PF00891.18 GAP93370.1 - 1.2e-23 83.6 0.0 2.5e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 GAP93370.1 - 0.029 15.1 0.0 0.1 13.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DDE_1 PF03184.19 GAP93371.1 - 6.5e-31 107.3 1.3 6.5e-31 107.3 1.3 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 GAP93371.1 - 4.8e-12 45.4 1.8 4.8e-12 45.4 1.8 2.1 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 GAP93371.1 - 1.3e-08 34.7 0.3 8e-08 32.2 0.2 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Aldo_ket_red PF00248.21 GAP93372.1 - 1e-53 182.5 0.0 1.3e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Beta-lactamase PF00144.24 GAP93373.1 - 1.1e-28 100.4 0.1 1.8e-28 99.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase zf-C3HC4_3 PF13920.6 GAP93374.1 - 1.2 9.1 12.3 1.8 8.5 6.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_S49_N PF08496.10 GAP93374.1 - 9.4 6.3 9.4 0.57 10.2 2.4 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Cupin_2 PF07883.11 GAP93375.1 - 4.6e-07 29.4 0.0 8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 GAP93375.1 - 0.0087 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Arylsulfotran_2 PF14269.6 GAP93376.1 - 7.5e-50 170.0 1.7 9.7e-50 169.6 1.7 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 GAP93376.1 - 2.3e-15 56.4 1.1 6e-15 55.0 0.3 2.0 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) FlgD_ig PF13860.6 GAP93376.1 - 1 9.3 3.8 12 5.8 0.1 3.4 4 0 0 4 4 4 0 FlgD Ig-like domain Y_phosphatase3 PF13350.6 GAP93377.1 - 2.3e-50 171.8 0.0 2.7e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 GAP93377.1 - 0.00033 20.3 0.0 0.00087 18.9 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 GAP93377.1 - 0.0014 18.3 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 GAP93377.1 - 0.0032 16.5 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 GAP93377.1 - 0.004 17.0 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 GAP93377.1 - 0.036 14.4 0.1 0.094 13.0 0.1 1.7 1 1 1 2 2 2 0 Rit1 DUSP-like domain AnmK PF03702.14 GAP93377.1 - 0.14 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase Glyco_hydro_20 PF00728.22 GAP93378.1 - 4.7e-11 42.7 0.0 3.5e-08 33.2 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain WD40 PF00400.32 GAP93379.1 - 1.7e-55 183.7 12.0 6.2e-09 36.3 0.2 8.6 8 2 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP93379.1 - 2e-10 40.8 0.0 0.014 15.7 0.0 4.8 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 GAP93379.1 - 3.1e-08 32.7 0.1 0.00027 19.7 0.1 4.1 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 GAP93379.1 - 3.5e-05 22.7 0.0 0.016 14.0 0.0 3.1 3 0 0 3 3 3 1 Nup133 N terminal like LisH PF08513.11 GAP93379.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 LisH Pox_A_type_inc PF04508.12 GAP93379.1 - 0.17 11.8 0.2 0.37 10.7 0.2 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat CLASP_N PF12348.8 GAP93380.1 - 0.00032 20.3 0.0 0.0023 17.6 0.0 2.1 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 GAP93380.1 - 0.00092 19.3 3.2 3.6 8.1 0.1 4.9 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 GAP93380.1 - 0.0018 18.3 0.3 0.035 14.2 0.1 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAP93380.1 - 0.002 16.7 0.3 0.53 8.8 0.0 2.4 2 1 0 2 2 2 2 Adaptin N terminal region TAN PF11640.8 GAP93380.1 - 0.0096 16.1 0.1 0.041 14.0 0.1 2.1 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair Syntaxin PF00804.25 GAP93380.1 - 0.026 14.2 2.4 0.085 12.5 2.4 1.8 1 0 0 1 1 1 0 Syntaxin TMCO5 PF14992.6 GAP93380.1 - 0.081 12.5 5.3 0.14 11.7 5.3 1.2 1 0 0 1 1 1 0 TMCO5 family DCB PF16213.5 GAP93380.1 - 0.089 12.5 0.5 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 CENP-F_N PF10481.9 GAP93380.1 - 0.27 10.8 6.3 0.045 13.4 1.3 2.1 2 0 0 2 2 2 0 Cenp-F N-terminal domain CCDC144C PF14915.6 GAP93380.1 - 0.63 9.1 11.3 1.2 8.2 11.3 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Atg14 PF10186.9 GAP93380.1 - 0.88 8.6 3.6 1.9 7.5 3.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 GAP93380.1 - 1.3 9.1 12.3 3.3 7.8 12.3 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Pil1 PF13805.6 GAP93380.1 - 1.5 8.3 10.0 3 7.3 10.0 1.4 1 0 0 1 1 1 0 Eisosome component PIL1 Jnk-SapK_ap_N PF09744.9 GAP93380.1 - 1.5 9.0 12.4 4.7 7.4 12.4 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HALZ PF02183.18 GAP93380.1 - 2.6 8.3 12.6 2.2 8.6 3.4 3.1 3 0 0 3 3 2 0 Homeobox associated leucine zipper APC_N_CC PF16689.5 GAP93380.1 - 2.8 8.1 7.4 1.4 9.1 1.2 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Rootletin PF15035.6 GAP93380.1 - 3 7.8 17.3 2.8 7.9 6.0 2.9 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Cupin_8 PF13621.6 GAP93381.1 - 0.017 14.9 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Cupin-like domain Methyltransf_25 PF13649.6 GAP93382.1 - 1e-14 55.0 0.1 1.8e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP93382.1 - 5.9e-13 49.3 0.1 9.7e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 GAP93382.1 - 6e-10 39.2 0.0 7.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP93382.1 - 8.5e-10 39.3 0.0 1.3e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP93382.1 - 8.6e-10 38.6 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 GAP93382.1 - 6.6e-05 22.4 0.1 8.7e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 GAP93382.1 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 GAP93382.1 - 0.00038 19.9 0.0 0.0005 19.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 GAP93382.1 - 0.0072 15.3 0.0 0.0098 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.16 GAP93382.1 - 0.013 14.1 0.0 0.015 13.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 GAP93382.1 - 0.024 14.6 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.12 GAP93382.1 - 0.051 12.8 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein ADH_zinc_N PF00107.26 GAP93382.1 - 0.086 12.8 0.5 0.22 11.5 0.5 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DIOX_N PF14226.6 GAP93383.1 - 2.3e-21 76.7 0.1 3.3e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 GAP93383.1 - 2.8e-13 50.2 0.0 5e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BRX PF08381.11 GAP93383.1 - 0.037 13.4 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 HET PF06985.11 GAP93384.1 - 1.2e-12 48.4 6.6 1.6e-10 41.5 0.9 3.1 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 GAP93384.1 - 2.7e-07 31.2 0.0 1.1e-06 29.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 GAP93384.1 - 3.4e-07 30.3 0.0 7.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 GAP93384.1 - 0.00014 22.2 0.1 0.001 19.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 GAP93384.1 - 0.0055 16.0 0.1 1.1 8.4 0.0 2.6 2 0 0 2 2 2 2 KAP family P-loop domain AAA PF00004.29 GAP93384.1 - 0.013 16.0 0.0 0.049 14.1 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 GAP93384.1 - 0.015 15.7 0.1 0.13 12.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 GAP93384.1 - 0.091 13.3 0.0 0.43 11.1 0.0 2.2 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 GAP93384.1 - 0.24 11.5 1.1 1.6 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Glyco_hydro81C PF17652.1 GAP93386.1 - 1.3e-71 241.7 3.3 2.1e-71 241.0 3.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 GAP93386.1 - 1.7e-34 119.4 5.0 2.6e-34 118.9 5.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Fascin PF06268.13 GAP93386.1 - 0.00065 19.9 0.0 0.0032 17.7 0.0 2.1 1 1 1 2 2 2 1 Fascin domain RicinB_lectin_2 PF14200.6 GAP93386.1 - 0.001 19.8 3.1 0.072 13.8 1.5 3.2 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like MIG-14_Wnt-bd PF06664.12 GAP93387.1 - 0.82 8.8 6.4 1.5 8.0 0.1 2.3 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion FAD_binding_4 PF01565.23 GAP93388.1 - 1.4e-07 31.3 3.1 2.9e-07 30.3 3.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 GAP93388.1 - 0.00028 20.9 0.1 0.00058 19.9 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Porin_3 PF01459.22 GAP93391.1 - 3.2e-71 240.0 10.3 3.6e-71 239.8 10.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin PTS_EIIC PF02378.18 GAP93391.1 - 0.045 12.8 1.0 0.073 12.1 1.0 1.3 1 0 0 1 1 1 0 Phosphotransferase system, EIIC SHNi-TPR PF10516.9 GAP93394.1 - 3.4e-14 52.0 0.0 3.4e-14 52.0 0.0 2.3 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 GAP93394.1 - 7e-07 29.4 0.6 0.00044 20.5 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 GAP93394.1 - 0.00055 20.5 3.2 0.0036 17.9 0.1 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 GAP93394.1 - 0.0013 18.9 1.5 0.031 14.5 0.3 3.0 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 GAP93394.1 - 0.0013 18.7 8.2 0.46 10.7 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 GAP93394.1 - 0.0019 18.7 0.1 0.031 14.8 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 GAP93394.1 - 0.0056 17.0 0.0 0.23 11.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4618 PF15397.6 GAP93394.1 - 0.015 14.7 3.1 0.025 14.0 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF3856 PF12968.7 GAP93394.1 - 0.063 13.4 1.8 0.91 9.6 0.1 3.0 2 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 GAP93394.1 - 0.069 13.0 3.3 4.1 7.4 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 GAP93394.1 - 0.16 12.0 0.2 0.44 10.6 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat CDC50 PF03381.15 GAP93395.1 - 7.2e-79 265.2 0.0 9e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family zf-C2H2_2 PF12756.7 GAP93396.1 - 5.6e-26 90.8 0.5 8.8e-26 90.2 0.5 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) NOA36 PF06524.12 GAP93396.1 - 0.57 9.5 9.0 0.88 8.8 9.0 1.3 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 GAP93396.1 - 8.5 6.2 9.8 20 5.0 5.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region CorA PF01544.18 GAP93397.1 - 8e-05 22.1 0.1 0.00017 21.0 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein K-box PF01486.17 GAP93397.1 - 0.073 13.3 0.2 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 K-box region Thr_synth_N PF14821.6 GAP93398.1 - 4.9e-28 97.2 0.0 1.7e-27 95.4 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 GAP93398.1 - 2.9e-21 76.2 0.0 1.3e-20 74.0 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_4 PF07993.12 GAP93399.1 - 6.6e-34 117.2 0.0 9.7e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 GAP93399.1 - 7.5e-30 103.9 0.0 1.2e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 GAP93399.1 - 2.2e-09 37.1 0.0 4.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAP93399.1 - 2.1e-05 24.8 0.0 4.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 GAP93399.1 - 6.5e-05 22.9 0.0 0.00022 21.2 0.0 1.9 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 GAP93399.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 GAP93400.1 - 3.5e-34 118.3 23.6 3.5e-34 118.3 23.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 GAP93400.1 - 2.7e-10 39.7 15.3 5e-10 38.8 14.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter LapA_dom PF06305.11 GAP93400.1 - 0.41 10.5 0.1 0.41 10.5 0.1 3.4 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF4750 PF15938.5 GAP93400.1 - 1.1 8.9 4.9 5.5 6.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4750) Bromodomain PF00439.25 GAP93402.1 - 1.2e-35 121.4 5.6 1.2e-18 67.0 0.7 2.8 2 1 0 2 2 2 2 Bromodomain BAH PF01426.18 GAP93402.1 - 9.8e-20 70.6 2.1 1.6e-19 69.9 1.0 1.9 2 0 0 2 2 2 1 BAH domain CDC45 PF02724.14 GAP93402.1 - 0.0015 16.9 7.1 0.0015 16.9 7.1 2.7 3 0 0 3 3 3 1 CDC45-like protein YL1 PF05764.13 GAP93402.1 - 0.0027 17.9 12.0 0.0027 17.9 12.0 3.8 3 1 0 3 3 3 1 YL1 nuclear protein OTU PF02338.19 GAP93403.1 - 0.00013 22.4 0.0 0.00022 21.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease PAS_9 PF13426.7 GAP93404.1 - 6.8e-27 93.8 0.0 3.7e-17 62.5 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 GAP93404.1 - 5.6e-21 74.6 0.0 1.2e-11 44.7 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 GAP93404.1 - 9.6e-16 57.8 0.0 1.3e-05 25.1 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 GAP93404.1 - 4.9e-15 54.8 8.9 1e-14 53.9 8.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.6 GAP93404.1 - 1.5e-11 44.4 0.0 4e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 GAP93404.1 - 2.2e-08 34.3 0.0 0.0017 18.6 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 GAP93404.1 - 5.6e-06 27.0 0.0 0.14 12.8 0.0 3.9 3 1 1 4 4 4 1 PAS fold FmdA_AmdA PF03069.15 GAP93405.1 - 2.8e-179 595.8 0.0 3.2e-179 595.6 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.11 GAP93406.1 - 5.8e-16 59.2 0.6 3.7e-14 53.4 0.6 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Fructosamin_kin PF03881.14 GAP93407.1 - 6.2e-33 114.2 0.0 7.9e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 GAP93407.1 - 3.2e-06 27.3 0.0 4.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.16 GAP93408.1 - 1.2e-42 146.2 43.4 9.2e-40 136.6 41.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 GAP93408.1 - 1.2e-19 70.2 20.9 1.5e-19 69.8 20.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 GAP93408.1 - 2.7e-16 59.5 11.8 2.7e-16 59.5 11.8 3.0 3 1 1 4 4 4 1 Sugar (and other) transporter PALP PF00291.25 GAP93409.1 - 1.9e-30 106.3 0.0 3.9e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 GAP93409.1 - 4.7e-05 23.9 0.0 0.00013 22.5 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain FTA2 PF13095.6 GAP93410.1 - 1.2e-41 142.7 0.0 1.6e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Ifi-6-16 PF06140.13 GAP93411.1 - 1.5e-08 34.5 29.6 1.5e-08 34.5 29.6 2.2 1 1 0 1 1 1 1 Interferon-induced 6-16 family CPSF100_C PF13299.6 GAP93411.1 - 0.018 15.2 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ank_2 PF12796.7 GAP93412.1 - 1e-49 167.0 6.0 5.2e-17 62.2 0.1 3.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 GAP93412.1 - 3.3e-23 81.0 9.4 5.6e-05 23.4 0.2 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 GAP93412.1 - 1.1e-21 76.9 4.0 2.4e-07 31.2 0.0 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP93412.1 - 7.7e-21 73.9 7.4 6.8e-09 35.8 0.3 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP93412.1 - 4.8e-17 60.3 4.2 0.0026 18.1 0.1 5.9 5 0 0 5 5 5 4 Ankyrin repeat DUF724 PF05266.14 GAP93412.1 - 0.19 11.5 8.1 0.34 10.7 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FAM76 PF16046.5 GAP93412.1 - 0.2 11.0 3.7 0.29 10.4 3.7 1.2 1 0 0 1 1 1 0 FAM76 protein FUSC PF04632.12 GAP93412.1 - 1.2 7.6 3.3 1.7 7.1 3.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 GAP93412.1 - 4.7 7.7 11.9 8.8 6.9 11.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region GHMP_kinases_N PF00288.26 GAP93414.1 - 1.7e-17 63.4 1.5 3.9e-17 62.2 1.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 GAP93414.1 - 7e-07 29.5 0.0 1.7e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DUF2671 PF10877.8 GAP93414.1 - 0.16 11.7 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2671) HET PF06985.11 GAP93415.1 - 1.6e-21 77.2 0.0 3.7e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 GAP93416.1 - 1.5e-22 80.2 0.0 2.9e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP93416.1 - 1.5e-18 67.1 0.0 2.4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 GAP93417.1 - 2.6e-15 56.5 0.0 3.9e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 GAP93417.1 - 1.5e-07 31.0 0.1 5.3e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase FAD_binding_3 PF01494.19 GAP93418.1 - 2.3e-12 46.9 2.9 9.7e-05 21.8 0.3 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.27 GAP93418.1 - 0.034 14.7 0.1 0.069 13.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 GAP93418.1 - 0.1 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pectate_lyase_3 PF12708.7 GAP93420.1 - 1.3e-78 263.8 13.1 1.2e-66 224.6 6.8 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 GAP93420.1 - 0.072 12.8 0.2 0.34 10.6 0.2 2.2 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase PNTB PF02233.16 GAP93422.1 - 6.2e-174 579.2 27.8 6.2e-174 579.2 27.8 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 GAP93422.1 - 4.3e-73 245.1 0.9 7.2e-73 244.4 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 GAP93422.1 - 9.7e-49 165.2 0.5 4.5e-48 163.0 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 GAP93422.1 - 1e-30 106.0 2.8 1e-30 106.0 2.8 5.3 3 1 2 5 5 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 GAP93422.1 - 0.0021 17.5 0.3 0.7 9.2 0.1 2.9 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 GAP93422.1 - 0.016 14.4 0.1 0.038 13.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 GAP93422.1 - 0.018 15.1 0.4 0.14 12.1 0.1 2.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.22 GAP93422.1 - 0.019 14.7 0.6 0.1 12.3 0.6 2.4 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain NAD_binding_2 PF03446.15 GAP93422.1 - 0.039 14.1 1.7 0.51 10.5 0.1 2.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fumerase PF05681.14 GAP93422.1 - 0.043 13.2 0.2 0.078 12.4 0.2 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) PG_isomerase_N PF18353.1 GAP93422.1 - 0.055 13.9 2.8 0.11 12.9 0.1 2.9 3 0 0 3 3 3 0 Phosphoglucose isomerase N-terminal domain GIDA PF01134.22 GAP93422.1 - 0.099 11.7 1.1 0.16 11.0 1.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_31 PF13847.6 GAP93422.1 - 0.22 11.3 0.0 0.78 9.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_8 PF13450.6 GAP93422.1 - 2.7 8.3 6.6 0.29 11.4 0.5 2.7 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain CCSAP PF15748.5 GAP93423.1 - 1.1 9.4 16.4 1.3 9.1 16.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAM60A PF15396.6 GAP93423.1 - 4.9 7.1 7.7 6 6.8 7.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SAPS PF04499.15 GAP93423.1 - 9.1 4.9 10.8 9.7 4.8 10.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ras PF00071.22 GAP93424.1 - 1.9e-31 108.9 0.3 2.4e-31 108.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 GAP93424.1 - 9.2e-24 84.0 0.1 1.4e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 GAP93424.1 - 6.3e-07 29.0 0.1 8.7e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 GAP93424.1 - 0.00011 21.6 0.3 0.00016 21.1 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 GAP93424.1 - 0.00086 18.2 0.6 0.13 11.0 0.0 2.3 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) DUF1590 PF07629.11 GAP93424.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1590) TniB PF05621.11 GAP93424.1 - 0.049 13.0 0.0 9 5.7 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 GAP93424.1 - 0.32 10.1 2.6 0.57 9.3 0.1 2.3 1 1 2 3 3 3 0 G-protein alpha subunit AAA PF00004.29 GAP93427.1 - 4e-17 62.9 0.0 7.8e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 GAP93427.1 - 2.3e-05 24.9 1.0 8.3e-05 23.0 0.2 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 GAP93427.1 - 2.9e-05 24.4 0.5 0.00046 20.5 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 GAP93427.1 - 0.00023 21.2 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 GAP93427.1 - 0.0019 18.0 1.0 0.0038 17.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 GAP93427.1 - 0.0021 17.8 0.0 0.006 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 GAP93427.1 - 0.0037 17.6 0.1 0.0099 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 GAP93427.1 - 0.021 14.5 0.1 0.74 9.4 0.0 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Rad17 PF03215.15 GAP93427.1 - 0.038 13.9 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain FHA PF00498.26 GAP93427.1 - 0.047 14.0 0.0 0.67 10.4 0.0 2.5 2 0 0 2 2 2 0 FHA domain AAA_33 PF13671.6 GAP93427.1 - 0.07 13.3 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 GAP93427.1 - 0.1 12.3 0.1 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 GAP93427.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 GAP93427.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 GAP93427.1 - 0.17 12.1 0.8 1.3 9.2 0.0 2.6 2 2 1 3 3 3 0 AAA domain Cpn60_TCP1 PF00118.24 GAP93428.1 - 4.9e-160 533.4 0.1 5.5e-160 533.2 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 GAP93428.1 - 0.18 10.3 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like GCV_H PF01597.19 GAP93429.1 - 3.9e-31 107.5 0.1 4.9e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Porphobil_deam PF01379.20 GAP93430.1 - 8.5e-51 172.4 0.1 1.1e-50 172.0 0.1 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 GAP93430.1 - 2.1e-18 66.5 1.1 4e-18 65.6 1.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Acetyltransf_1 PF00583.25 GAP93431.1 - 1.3e-12 47.9 0.0 2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 GAP93431.1 - 1.2e-10 42.1 0.0 1.8e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 GAP93431.1 - 7.7e-05 23.0 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 GAP93431.1 - 0.00082 19.5 0.0 0.0015 18.7 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 GAP93431.1 - 0.0028 17.6 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 GAP93431.1 - 0.03 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PP2C PF00481.21 GAP93432.1 - 6.2e-23 81.8 0.0 1.8e-22 80.2 0.0 1.5 1 1 0 2 2 2 1 Protein phosphatase 2C p450 PF00067.22 GAP93433.1 - 1.4e-52 179.0 0.0 1.7e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 T3SS_basalb_I PF17001.5 GAP93433.1 - 0.23 12.1 0.0 0.5 11.0 0.0 1.5 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI Methyltransf_25 PF13649.6 GAP93434.1 - 2.2e-22 79.5 0.0 5.6e-22 78.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 GAP93434.1 - 2.6e-22 79.3 0.0 3.5e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 GAP93434.1 - 8.2e-22 77.7 0.0 1.6e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 GAP93434.1 - 3.8e-17 62.4 0.0 7.2e-16 58.2 0.0 2.1 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 GAP93434.1 - 1.6e-15 57.3 0.0 2.8e-15 56.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 GAP93434.1 - 9.4e-15 55.2 0.0 1.8e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 GAP93434.1 - 6.3e-10 39.2 0.0 8.9e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 GAP93434.1 - 1.8e-08 34.0 0.0 2.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 GAP93434.1 - 6.1e-08 32.5 0.0 8.2e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 GAP93434.1 - 9.6e-08 31.8 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 GAP93434.1 - 2.6e-06 27.2 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_24 PF13578.6 GAP93434.1 - 0.00016 22.7 0.0 0.00041 21.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 GAP93434.1 - 0.00018 21.6 0.0 0.00028 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase GCD14 PF08704.10 GAP93434.1 - 0.00019 21.2 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.20 GAP93434.1 - 0.00092 18.4 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 GAP93434.1 - 0.0034 17.0 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_3 PF01596.17 GAP93434.1 - 0.0057 15.9 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.17 GAP93434.1 - 0.0076 15.7 0.0 0.017 14.6 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 GAP93434.1 - 0.0077 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 GAP93434.1 - 0.0083 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 GAP93434.1 - 0.012 14.6 0.0 0.025 13.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_29 PF03141.16 GAP93434.1 - 0.027 13.1 0.0 0.034 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.11 GAP93434.1 - 0.053 13.2 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Fibrillarin PF01269.17 GAP93434.1 - 0.056 12.5 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin DOT1 PF08123.13 GAP93434.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Ferric_reduct PF01794.19 GAP93435.1 - 8e-19 68.0 10.6 8e-19 68.0 10.6 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 GAP93435.1 - 1.5e-08 34.7 0.0 2.8e-05 24.1 0.1 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 GAP93435.1 - 1.5e-07 31.7 0.0 0.0049 17.0 0.0 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Ctr PF04145.15 GAP93436.1 - 2.5e-11 44.4 0.0 2.9e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family FPN1 PF06963.12 GAP93437.1 - 3e-117 391.9 21.9 3.4e-117 391.7 21.9 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Ank_2 PF12796.7 GAP93438.1 - 4.8e-09 36.7 0.0 3.4e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP93438.1 - 2.2e-06 27.8 0.1 0.044 14.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP93438.1 - 7.1e-06 26.0 0.1 0.0022 18.4 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 GAP93438.1 - 2.5e-05 24.8 0.1 0.00015 22.3 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 GAP93438.1 - 0.00034 20.9 0.1 0.029 14.8 0.1 3.4 4 0 0 4 4 4 1 Ankyrin repeat Fig1 PF12351.8 GAP93439.1 - 3.6e-29 102.0 1.4 4.4e-29 101.8 1.4 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 Tlr3_TMD PF17968.1 GAP93439.1 - 0.061 13.5 5.1 0.88 9.8 1.8 2.5 2 0 0 2 2 2 0 Toll-like receptor 3 trans-membrane domain RRM_1 PF00076.22 GAP93440.1 - 1.1e-06 28.4 0.0 0.00012 21.9 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldedh PF00171.22 GAP93441.1 - 7.1e-133 443.5 0.0 7.9e-133 443.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 GAP93441.1 - 0.00027 20.1 0.0 0.00052 19.2 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) PBD PF00786.28 GAP93442.1 - 0.09 13.2 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 P21-Rho-binding domain Fungal_trans PF04082.18 GAP93443.1 - 4.2e-08 32.6 0.1 8.3e-08 31.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 GAP93443.1 - 0.78 9.9 3.4 1.8 8.8 3.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PP28 PF10252.9 GAP93445.1 - 1.9e-28 98.8 17.5 1.9e-28 98.8 17.5 3.3 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 YL1 PF05764.13 GAP93445.1 - 0.011 15.9 43.2 0.016 15.3 43.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein AMP-binding PF00501.28 GAP93446.1 - 7.7e-69 232.3 0.0 1.5e-68 231.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 GAP93446.1 - 1.6e-62 211.0 0.0 2.2e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 GAP93446.1 - 9.6e-09 35.0 0.0 1.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 GAP93446.1 - 5.9e-08 32.9 0.0 1.9e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 GAP93446.1 - 0.00079 18.5 0.0 0.0021 17.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 GAP93446.1 - 0.0077 17.2 0.0 0.049 14.6 0.0 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 GAP93446.1 - 0.0084 16.0 0.2 0.058 13.3 0.2 2.4 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 GAP93446.1 - 0.028 13.6 0.0 0.072 12.2 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.10 GAP93446.1 - 0.17 11.8 0.1 0.47 10.3 0.1 1.8 1 1 0 1 1 1 0 KR domain PP-binding PF00550.25 GAP93447.1 - 1.5e-11 44.5 0.1 2e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 GAP93447.1 - 3.3e-05 24.0 0.1 4.2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier Fer4 PF00037.27 GAP93448.1 - 1.5e-13 49.9 16.5 5.8e-08 32.2 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 GAP93448.1 - 9.2e-13 48.6 10.2 1.5e-12 47.9 10.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 GAP93448.1 - 2.3e-10 41.3 7.6 6.5e-05 23.8 0.4 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 GAP93448.1 - 1.1e-09 38.2 31.2 5.2e-06 26.5 12.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 GAP93448.1 - 1.3e-08 34.8 21.2 2.5e-06 27.5 12.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 GAP93448.1 - 4.2e-08 33.2 10.1 8.9e-08 32.2 10.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 GAP93448.1 - 3.3e-07 30.7 19.0 0.00011 22.5 11.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 GAP93448.1 - 1.4e-06 28.1 17.1 0.00038 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 GAP93448.1 - 4.4e-06 26.5 11.8 0.0094 16.0 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 GAP93448.1 - 8.5e-06 25.9 11.4 0.00028 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 GAP93448.1 - 0.00029 21.3 11.5 0.042 14.4 12.6 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 GAP93448.1 - 0.006 16.8 5.5 0.76 10.1 0.5 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain ETF_QO PF05187.13 GAP93448.1 - 0.039 14.1 5.1 0.19 11.9 0.4 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 GAP93448.1 - 0.067 13.7 15.1 0.71 10.5 4.3 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 GAP93448.1 - 0.068 13.4 8.8 1.2 9.4 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 GAP93448.1 - 0.23 12.5 15.5 0.41 11.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 GAP93448.1 - 0.71 10.8 11.8 3.4 8.6 1.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain PCMT PF01135.19 GAP93449.1 - 3.1e-36 125.1 0.0 6.2e-34 117.6 0.0 2.1 1 1 1 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 GAP93449.1 - 1.6e-05 24.8 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 GAP93449.1 - 0.0013 18.7 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 GAP93449.1 - 0.0031 18.2 0.0 0.0054 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 GAP93449.1 - 0.032 13.8 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 GAP93449.1 - 0.035 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 GAP93449.1 - 0.039 14.6 0.0 0.067 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 GAP93449.1 - 0.066 13.0 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 GAP93449.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Mito_carr PF00153.27 GAP93451.1 - 3.9e-52 174.1 3.5 1.4e-20 73.0 0.3 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2370 PF10176.9 GAP93453.1 - 2.6e-87 292.2 0.0 4.6e-87 291.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) MLANA PF14991.6 GAP93453.1 - 0.12 12.6 0.5 0.35 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein melan-A DUF1996 PF09362.10 GAP93454.1 - 2.1e-81 273.3 0.2 2.9e-81 272.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.11 GAP93455.1 - 3.2e-23 82.7 0.0 9.5e-23 81.2 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AltA1 PF16541.5 GAP93455.1 - 0.0014 19.5 0.2 0.21 12.4 0.0 2.4 2 0 0 2 2 2 1 Alternaria alternata allergen 1 PaRep2a PF07903.11 GAP93455.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 PaRep2a protein Baculo_PEP_C PF04513.12 GAP93457.1 - 0.0015 18.5 1.3 0.0051 16.9 1.3 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 GAP93457.1 - 0.004 17.1 6.1 0.0086 16.0 6.1 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4527 PF15030.6 GAP93457.1 - 0.0048 16.4 0.8 0.0067 15.9 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4527) Tmemb_cc2 PF10267.9 GAP93457.1 - 0.0063 15.7 0.2 0.008 15.4 0.2 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein DUF1664 PF07889.12 GAP93457.1 - 0.0091 16.0 0.1 0.014 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) FAM184 PF15665.5 GAP93457.1 - 0.021 14.6 0.6 0.032 14.0 0.6 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Prominin PF05478.11 GAP93457.1 - 0.13 10.2 0.1 0.16 9.9 0.1 1.1 1 0 0 1 1 1 0 Prominin T7SS_ESX_EspC PF10824.8 GAP93457.1 - 0.31 11.5 6.2 0.088 13.3 2.2 2.1 2 1 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Abhydrolase_3 PF07859.13 GAP93458.1 - 1.6e-34 119.7 0.0 1.3e-33 116.6 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 GAP93458.1 - 5.6e-07 28.8 0.0 8.1e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 GAP93458.1 - 0.011 14.6 0.0 0.53 9.1 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase GMC_oxred_N PF00732.19 GAP93460.1 - 3.1e-27 95.7 0.0 4.2e-21 75.6 0.0 3.2 2 1 1 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.13 GAP93460.1 - 7.9e-26 91.3 0.0 1.6e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 GAP93460.1 - 9.9e-06 25.0 0.0 0.00038 19.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 GAP93460.1 - 0.0025 18.0 0.0 0.0067 16.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 GAP93460.1 - 0.016 14.4 0.2 0.028 13.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 GAP93460.1 - 0.05 12.9 0.7 3.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 GAP93460.1 - 0.064 12.3 0.4 0.38 9.8 0.5 1.9 2 0 0 2 2 2 0 FAD binding domain CoatB PF10389.9 GAP93460.1 - 0.14 12.0 1.6 0.46 10.4 1.6 1.9 1 0 0 1 1 1 0 Bacteriophage coat protein B HI0933_like PF03486.14 GAP93460.1 - 0.22 10.2 0.2 0.35 9.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein ABC_tran PF00005.27 GAP93461.1 - 1e-25 90.9 0.0 1.8e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 GAP93461.1 - 7.4e-08 32.1 0.9 7.4e-08 32.1 0.9 3.5 3 1 1 4 4 4 2 ABC-2 type transporter RsgA_GTPase PF03193.16 GAP93461.1 - 0.00022 21.2 0.2 0.00049 20.0 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 GAP93461.1 - 0.0071 15.9 0.2 0.016 14.8 0.1 1.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 GAP93461.1 - 0.027 14.6 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 GAP93461.1 - 0.032 14.0 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 GAP93461.1 - 0.036 13.8 1.4 0.087 12.6 1.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 GAP93461.1 - 0.039 14.0 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Dynamin family Mntp PF02659.15 GAP93461.1 - 0.087 12.6 1.1 0.23 11.2 1.1 1.7 1 0 0 1 1 1 0 Putative manganese efflux pump IIGP PF05049.13 GAP93461.1 - 0.2 10.6 0.3 0.32 10.0 0.3 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 GAP93461.1 - 1.8 8.6 3.3 3.1 7.8 3.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain COX15-CtaA PF02628.15 GAP93462.1 - 3.1e-106 355.1 8.6 3.1e-106 355.1 8.6 2.0 2 1 0 2 2 2 1 Cytochrome oxidase assembly protein DUF3619 PF12279.8 GAP93462.1 - 5 7.5 7.7 14 6.0 7.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) FAM199X PF15814.5 GAP93462.1 - 5.5 5.9 6.0 8 5.4 6.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X Patatin PF01734.22 GAP93463.1 - 3.7e-24 86.1 0.0 9.8e-24 84.7 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.27 GAP93463.1 - 0.0017 18.9 0.0 0.0049 17.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 GAP93463.1 - 0.0038 17.2 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 GAP93463.1 - 0.0065 15.8 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin zf-C3HC4 PF00097.25 GAP93463.1 - 0.0077 16.1 3.8 0.0077 16.1 3.8 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 GAP93463.1 - 0.016 15.0 17.9 0.04 13.8 4.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MMR_HSR1 PF01926.23 GAP93463.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 GAP93463.1 - 0.025 14.9 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-RING_UBOX PF13445.6 GAP93463.1 - 0.083 12.9 10.4 0.02 14.9 5.7 2.6 2 1 0 2 2 2 0 RING-type zinc-finger TsaE PF02367.17 GAP93463.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 GAP93463.1 - 0.14 11.9 0.1 0.36 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 GAP93463.1 - 0.19 11.8 0.0 0.58 10.2 0.0 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain zf-RING_2 PF13639.6 GAP93463.1 - 0.6 10.5 20.3 0.071 13.4 5.3 2.9 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 GAP93463.1 - 7.9 6.4 19.8 0.22 11.4 4.9 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ank_2 PF12796.7 GAP93464.1 - 9.3e-61 202.4 5.9 1.3e-09 38.5 0.2 9.6 6 3 4 10 10 10 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 GAP93464.1 - 1.3e-40 136.9 18.6 4e-06 27.0 0.0 14.5 7 5 9 16 16 16 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 GAP93464.1 - 1e-35 121.6 19.6 0.00015 22.2 0.1 12.0 9 4 3 13 13 13 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP93464.1 - 4.9e-30 100.2 22.3 0.06 13.9 0.0 17.2 17 1 1 18 18 18 6 Ankyrin repeat Ank PF00023.30 GAP93464.1 - 5.3e-15 55.1 18.0 0.0024 18.2 0.0 13.3 15 0 0 15 15 15 3 Ankyrin repeat DUF3447 PF11929.8 GAP93464.1 - 0.028 14.4 2.9 16 5.5 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3447) APH PF01636.23 GAP93465.1 - 8.5e-07 29.1 1.5 0.00012 22.0 1.5 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP93465.1 - 0.0032 17.1 1.0 0.013 15.1 0.1 2.4 3 0 0 3 3 3 1 Choline/ethanolamine kinase Ank_2 PF12796.7 GAP93466.1 - 1.3e-77 256.5 0.3 3.1e-10 40.5 0.0 10.3 6 3 5 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 GAP93466.1 - 3.6e-46 154.9 12.5 8.9e-06 26.2 0.0 14.0 8 4 7 16 16 16 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 GAP93466.1 - 9e-43 143.8 18.1 6.1e-08 32.8 0.0 14.3 9 3 6 15 15 15 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 GAP93466.1 - 3.8e-39 128.2 7.9 0.16 12.6 0.0 19.8 21 0 0 21 21 21 8 Ankyrin repeat Ank PF00023.30 GAP93466.1 - 3.9e-29 99.8 24.9 0.0096 16.3 0.0 15.8 16 1 0 16 16 16 7 Ankyrin repeat FBD PF08387.10 GAP93466.1 - 0.099 12.5 0.1 17 5.4 0.0 2.8 2 0 0 2 2 2 0 FBD C1_2 PF03107.16 GAP93466.1 - 1.1 9.7 13.7 2.3 8.6 13.7 1.6 1 0 0 1 1 1 0 C1 domain DNA_topoisoIV PF00521.20 GAP93467.1 - 6.1e-121 404.3 0.7 6.1e-121 404.3 0.7 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 GAP93467.1 - 2.7e-46 157.0 4.1 1.5e-45 154.6 4.1 2.4 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 GAP93467.1 - 2.9e-22 79.0 0.1 7.5e-22 77.6 0.1 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 GAP93467.1 - 2e-12 47.6 0.0 5.3e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 GAP93467.1 - 4.2e-06 26.9 0.0 1.7e-05 24.9 0.0 2.1 1 0 0 1 1 1 1 Toprim domain Reticulon PF02453.17 GAP93468.1 - 6.3e-34 117.2 2.3 9e-34 116.7 2.3 1.2 1 0 0 1 1 1 1 Reticulon I-set PF07679.16 GAP93468.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Immunoglobulin I-set domain RabGAP-TBC PF00566.18 GAP93469.1 - 2.2e-48 164.7 0.0 2.6e-47 161.3 0.0 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Borrelia_orfA PF02414.15 GAP93469.1 - 1.5 8.4 5.0 2.7 7.6 5.0 1.3 1 0 0 1 1 1 0 Borrelia ORF-A DUF1664 PF07889.12 GAP93469.1 - 2.9 7.9 7.8 0.32 11.0 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 GAP93469.1 - 4 5.8 15.2 5.1 5.5 12.7 2.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family Peptidase_C10 PF01640.17 GAP93469.1 - 8.6 6.6 5.9 5.8 7.2 0.6 2.3 2 0 0 2 2 2 0 Peptidase C10 family FAM76 PF16046.5 GAP93470.1 - 0.029 13.7 17.3 0.046 13.1 17.3 1.2 1 0 0 1 1 1 0 FAM76 protein Zip PF02535.22 GAP93470.1 - 1.3 8.2 10.6 1.7 7.8 10.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S64 PF08192.11 GAP93470.1 - 1.4 7.3 20.4 2.4 6.6 20.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 MDM10 PF12519.8 GAP93470.1 - 1.5 7.6 11.2 2.2 7.1 11.2 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Otopetrin PF03189.13 GAP93470.1 - 1.7 7.4 6.8 2.1 7.1 6.8 1.2 1 0 0 1 1 1 0 Otopetrin Membralin PF09746.9 GAP93470.1 - 1.8 7.5 7.9 2.5 7.1 7.9 1.3 1 0 0 1 1 1 0 Tumour-associated protein Eapp_C PF10238.9 GAP93470.1 - 1.9 8.5 16.8 0.82 9.7 13.0 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein SID-1_RNA_chan PF13965.6 GAP93470.1 - 5.3 5.3 5.3 7.1 4.9 5.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EOS1 PF12326.8 GAP93470.1 - 6.8 6.6 7.2 12 5.8 7.2 1.5 1 0 0 1 1 1 0 N-glycosylation protein Macoilin PF09726.9 GAP93470.1 - 7.2 5.0 17.1 8.8 4.7 17.1 1.1 1 0 0 1 1 1 0 Macoilin family TatD_DNase PF01026.21 GAP93471.1 - 1.4e-31 109.8 0.0 2e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Ank_5 PF13857.6 GAP93473.1 - 2e-15 56.7 0.2 8.1e-13 48.3 0.1 4.1 5 0 0 5 5 5 1 Ankyrin repeats (many copies) VPS9 PF02204.18 GAP93473.1 - 2.9e-15 56.4 0.0 9.3e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 GAP93473.1 - 5.1e-10 39.8 0.0 0.0028 18.2 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 GAP93473.1 - 0.00026 21.2 0.1 0.27 11.9 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 GAP93473.1 - 0.0005 20.6 0.1 0.81 10.3 0.0 4.4 3 1 2 5 5 5 1 Ankyrin repeats (many copies) NCU-G1 PF15065.6 GAP93473.1 - 0.0076 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 PX PF00787.24 GAP93473.1 - 0.012 15.6 0.1 0.047 13.7 0.0 2.1 2 0 0 2 2 2 0 PX domain Ank PF00023.30 GAP93473.1 - 0.06 13.8 0.1 8.2 7.1 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat Chal_sti_synt_C PF02797.15 GAP93474.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.0 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Abhydrolase_6 PF12697.7 GAP93475.1 - 9.6e-14 52.5 0.1 1.2e-13 52.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 GAP93475.1 - 3.3e-05 23.3 0.0 0.00074 18.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Dyp_perox PF04261.12 GAP93476.1 - 4.8e-08 32.4 0.1 1.8e-06 27.2 0.0 2.7 3 1 0 3 3 3 2 Dyp-type peroxidase family CBM_20 PF00686.19 GAP93477.1 - 3.8e-26 90.8 0.0 6e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain Glyco_hydro_61 PF03443.14 GAP93477.1 - 0.038 13.9 0.2 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 61 TIP120 PF08623.10 GAP93478.1 - 4.8e-69 231.4 4.7 2.8e-67 225.7 0.0 4.7 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 GAP93478.1 - 6e-12 45.8 12.6 0.013 15.9 0.0 8.5 7 2 2 9 9 8 4 HEAT repeats HEAT PF02985.22 GAP93478.1 - 1.1e-08 34.6 18.4 0.19 12.1 0.1 9.4 10 0 0 10 10 9 3 HEAT repeat RTP1_C1 PF10363.9 GAP93478.1 - 0.00034 20.7 7.5 0.023 14.9 0.1 5.9 6 1 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 GAP93478.1 - 0.0024 18.5 2.5 13 6.5 0.0 7.3 8 3 2 10 10 10 1 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 GAP93478.1 - 0.0028 17.3 2.4 0.23 11.0 0.0 3.5 2 1 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.7 GAP93478.1 - 0.0086 16.1 9.9 1.5 8.8 0.1 6.0 6 1 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 GAP93478.1 - 0.016 13.8 17.8 0.67 8.4 0.2 6.1 6 2 0 6 6 6 0 Adaptin N terminal region NinF PF05810.12 GAP93478.1 - 0.047 13.6 0.1 0.59 10.0 0.0 2.4 2 0 0 2 2 2 0 NinF protein Sigma70_ner PF04546.13 GAP93478.1 - 0.11 12.4 3.9 4.4 7.1 2.2 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Cnd3 PF12719.7 GAP93478.1 - 0.15 11.3 0.7 35 3.5 0.0 4.4 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain Ecm29 PF13001.7 GAP93478.1 - 0.17 10.5 1.8 2.2 6.9 0.1 3.5 3 2 0 3 3 3 0 Proteasome stabiliser CENP-B_dimeris PF09026.10 GAP93478.1 - 6.3 7.3 12.4 15 6.1 12.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NmrA PF05368.13 GAP93479.1 - 4e-13 49.5 0.0 5.2e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 GAP93479.1 - 6e-06 26.3 0.8 8.9e-06 25.7 0.8 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF4232 PF14016.6 GAP93479.1 - 0.0018 18.4 0.1 0.004 17.3 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4232) MIP PF00230.20 GAP93480.1 - 2.4e-48 164.8 16.5 3e-48 164.5 16.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_43 PF04616.14 GAP93481.1 - 6.3e-13 48.7 4.4 1e-12 48.0 4.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 APH PF01636.23 GAP93482.1 - 4e-12 46.6 0.0 8.8e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 GAP93482.1 - 1.5e-05 24.7 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 GAP93482.1 - 0.0025 16.7 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Haspin_kinase PF12330.8 GAP93482.1 - 0.036 13.0 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 GAP93482.1 - 0.06 12.7 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 GAP93482.1 - 0.2 10.8 0.0 0.93 8.6 0.0 1.8 2 0 0 2 2 2 0 Fructosamine kinase UAA PF08449.11 GAP93483.1 - 4.6e-102 341.3 6.9 5.5e-102 341.0 6.9 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 GAP93483.1 - 0.00038 19.7 3.8 0.0007 18.9 3.8 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 GAP93483.1 - 0.04 14.1 25.9 0.94 9.7 1.4 4.0 2 1 2 4 4 4 0 EamA-like transporter family TssN PF17555.2 GAP93483.1 - 5.6 6.3 11.0 0.093 12.1 2.0 2.3 3 0 0 3 3 3 0 Type VI secretion system, TssN WD40 PF00400.32 GAP93484.1 - 2.5e-13 50.3 2.6 0.19 12.7 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 GAP93484.1 - 0.0087 16.3 0.1 2.6 8.4 0.0 3.8 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Dynamin_M PF01031.20 GAP93485.1 - 3.4e-111 371.0 0.0 6.1e-111 370.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 GAP93485.1 - 4e-56 189.7 0.5 1e-55 188.3 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 GAP93485.1 - 9.1e-31 105.9 0.9 9.1e-31 105.9 0.9 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 GAP93485.1 - 5.8e-05 23.2 0.2 0.0003 20.8 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase TAF4 PF05236.14 GAP93485.1 - 0.0037 17.1 0.8 0.0061 16.3 0.8 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family LRR_4 PF12799.7 GAP93486.1 - 2.3e-08 34.2 10.5 0.015 15.7 0.0 5.7 7 0 0 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 GAP93486.1 - 1.1e-06 28.2 9.9 0.079 13.1 0.0 5.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 GAP93486.1 - 3.5e-05 23.8 0.3 12 6.9 0.1 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 GAP93486.1 - 4.8e-05 23.0 10.0 0.87 9.4 0.0 5.1 4 1 0 4 4 4 2 Leucine rich repeat LKAAEAR PF15478.6 GAP93486.1 - 0.8 10.0 5.8 7.7 6.8 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function with LKAAEAR motif F-box PF00646.33 GAP93487.1 - 0.0021 17.9 0.1 0.005 16.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 GAP93487.1 - 0.097 12.6 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 F-box-like MTCP1 PF08991.10 GAP93488.1 - 3.8e-27 94.3 5.3 4.5e-27 94.0 5.3 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 GAP93488.1 - 0.018 15.2 4.3 0.03 14.5 4.3 1.4 1 0 0 1 1 1 0 CHCH domain Cmc1 PF08583.10 GAP93488.1 - 0.57 10.2 6.3 0.14 12.2 2.0 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Nup84_Nup100 PF04121.13 GAP93489.1 - 1.1e-184 615.5 0.0 1.4e-184 615.2 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 TetR_C_7 PF14246.6 GAP93489.1 - 0.098 12.7 0.1 0.83 9.7 0.0 2.5 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain RPN13_C PF16550.5 GAP93489.1 - 0.098 12.8 1.3 5.7 7.2 0.3 3.0 2 0 0 2 2 2 0 UCH-binding domain Mod_r PF07200.13 GAP93490.1 - 4.5e-34 117.7 1.8 5.5e-34 117.4 1.8 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF4360 PF14273.6 GAP93491.1 - 2.2e-35 122.1 0.2 2.7e-35 121.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) zf-C3HC4 PF00097.25 GAP93492.1 - 0.0003 20.6 6.6 0.0003 20.6 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 GAP93492.1 - 0.003 17.9 6.6 0.003 17.9 6.6 2.5 2 0 0 2 2 2 1 Ring finger domain Abhydrolase_4 PF08386.10 GAP93493.1 - 1.7e-17 63.4 0.0 4e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 GAP93493.1 - 1.1e-09 38.3 0.0 1.2e-06 28.4 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Rosellinia_necatrix-ASM144559v1/GCA_001445595.1_ASM144559v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Rosellinia_necatrix-ASM144559v1/GCA_001445595.1_ASM144559v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Rosellinia_necatrix-ASM144559v1/GCA_001445595.1_ASM144559v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Rosellinia_necatrix-ASM144559v1/GCA_001445595.1_ASM144559v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 05:06:57 2019 # [ok]